272568:GDIA RS04550
gene id: 272568:GDIA_RS04550
uniprot id: B5ZFG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

272568:GDIA RS02405
gene id: 272568:GDIA_RS02405
uniprot id: B5ZCK9
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.

272568:GDIA RS06890
gene id: 272568:GDIA_RS06890
uniprot id: A9H8R6
names: Subcellular Location Annotation
messages: Membrane

272568:GDIA RS10515
gene id: 272568:GDIA_RS10515
uniprot id: A9HF68
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane
messages: Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins.

272568:GDIA RS08155
gene id: 272568:GDIA_RS08155
uniprot id: A9GZV7
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

272568:GDIA RS07465
gene id: 272568:GDIA_RS07465
uniprot id: A9H6F4
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

272568:GDIA RS01315
gene id: 272568:GDIA_RS01315
uniprot id: A9HJZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase bacterial subunit 4 family.
messages: Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron.
messages: Heterooctamer of two A chains, two B chains, two C chains and two D chains.
messages: Membrane

272568:GDIA RS03085
gene id: 272568:GDIA_RS03085
uniprot id: B5ZDT6
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

272568:GDIA RS07665
gene id: 272568:GDIA_RS07665
uniprot id: B5ZIS3
names: Cofactor
messages: Binds 1 zinc ion per subunit.

272568:GDIA RS00440
gene id: 272568:GDIA_RS00440
uniprot id: A9HIQ8
names: Similarity
messages: Belongs to the TlyA family.

272568:GDIA RS07400
gene id: 272568:GDIA_RS07400
uniprot id: A9H7Z5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glutamine synthetase family.
messages: Catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia.
messages: Cytoplasm
messages: Oligomer of 12 subunits arranged in the form of two hexagons.
messages: Oligomer of 12 subunits arranged in the form of two hexameric ring.

272568:GDIA RS09995
gene id: 272568:GDIA_RS09995
uniprot id: A9HEC6
names: Function
names: Similarity
messages: Belongs to the PqqA family.
messages: Required for coenzyme pyrroloquinoline quinone (PQQ) biosynthesis. PQQ is probably formed by cross-linking a specific glutamate to a specific tyrosine residue and excising these residues from the peptide.

272568:GDIA RS15695
gene id: 272568:GDIA_RS15695
uniprot id: A9H0U2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

272568:GDIA RS14595
gene id: 272568:GDIA_RS14595
uniprot id: B5ZIA6
names: Similarity
messages: Belongs to the Nudix hydrolase family.

272568:GDIA RS11280
gene id: 272568:GDIA_RS11280
uniprot id: B5ZEK2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MobA family.
messages: Cytoplasm
messages: Monomer.
messages: The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.
messages: Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.

272568:GDIA RS06530
gene id: 272568:GDIA_RS06530
uniprot id: A9H9B4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
messages: Cytoplasm

272568:GDIA RS07025
gene id: 272568:GDIA_RS07025
uniprot id: B5ZI49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

272568:GDIA RS07770
gene id: 272568:GDIA_RS07770
uniprot id: A9H5Z1
names: Function
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.
messages: This protein is a Fe-Mo-cofactor biosynthetic component.

272568:GDIA RS17400
gene id: 272568:GDIA_RS17400
uniprot id: A9HHB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Membrane

272568:GDIA RS14095
gene id: 272568:GDIA_RS14095
uniprot id: B5ZHR6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

272568:GDIA RS06040
gene id: 272568:GDIA_RS06040
uniprot id: B5ZH32
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvB family.
messages: Forms a complex with RuvA.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.

272568:GDIA RS08885
gene id: 272568:GDIA_RS08885
uniprot id: B5ZL05
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK.

272568:GDIA RS17380
gene id: 272568:GDIA_RS17380
uniprot id: B5ZM75
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cytoplasm
messages: Probable catalytic subunit of a protein translocase for flagellum-specific export, or a proton translocase involved in local circuits at the flagellum.

272568:GDIA RS12000
gene id: 272568:GDIA_RS12000
uniprot id: B5ZF84
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

272568:GDIA RS00455
gene id: 272568:GDIA_RS00455
uniprot id: A9HIR6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

272568:GDIA RS15985
gene id: 272568:GDIA_RS15985
uniprot id: B5ZKE2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

272568:GDIA RS01005
gene id: 272568:GDIA_RS01005
uniprot id: B5ZKN4
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

272568:GDIA RS17505
gene id: 272568:GDIA_RS17505
uniprot id: B5ZCX5
names: Subcellular Location Annotation
messages: Periplasm

272568:GDIA RS17680
gene id: 272568:GDIA_RS17680
uniprot id: A9HHS1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

272568:GDIA RS02005
gene id: 272568:GDIA_RS02005
uniprot id: A9HL42
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YajC family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the SecDF-YidC-YajC translocase complex. The SecDF-YidC-YajC translocase forms a supercomplex with SecYEG, called the holo-translocon (HTL).
messages: The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions.

272568:GDIA RS10595
gene id: 272568:GDIA_RS10595
uniprot id: A9HFC8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell inner membrane
messages: Membrane

272568:GDIA RS02710
gene id: 272568:GDIA_RS02710
uniprot id: B5ZD98
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
messages: Heterotetramer of two alpha and two beta chains arranged as a dimer of alpha/beta heterodimers.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl group blocking the N-terminus of the alpha chain.

272568:GDIA RS04470
gene id: 272568:GDIA_RS04470
uniprot id: A9HPV3
names: Subcellular Location Annotation
messages: Membrane

272568:GDIA RS00340
gene id: 272568:GDIA_RS00340
uniprot id: A9HIL1
names: Subcellular Location Annotation
messages: Membrane

272568:GDIA RS15890
gene id: 272568:GDIA_RS15890
uniprot id: B5ZJU5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

272568:GDIA RS07365
gene id: 272568:GDIA_RS07365
uniprot id: A9H812
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

272568:GDIA RS09990
gene id: 272568:GDIA_RS09990
uniprot id: A9HEC4
names: Function
names: Similarity
messages: Belongs to the PqqB family.
messages: May be involved in the transport of PQQ or its precursor to the periplasm.

272568:GDIA RS08185
gene id: 272568:GDIA_RS08185
uniprot id: B5ZJL1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

272568:GDIA RS02900
gene id: 272568:GDIA_RS02900
uniprot id: A9HMB4
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

272568:GDIA RS05425
gene id: 272568:GDIA_RS05425
uniprot id: B5ZGG6
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

272568:GDIA RS04160
gene id: 272568:GDIA_RS04160
uniprot id: B5ZEZ1
names: Subcellular Location Annotation
messages: Membrane

272568:GDIA RS14525
gene id: 272568:GDIA_RS14525
uniprot id: B5ZI93
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

272568:GDIA RS01335
gene id: 272568:GDIA_RS01335
uniprot id: B5ZKU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

272568:GDIA RS00450
gene id: 272568:GDIA_RS00450
uniprot id: A9HIR3
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

272568:GDIA RS12040
gene id: 272568:GDIA_RS12040
uniprot id: B5ZF91
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIIB subfamily.
messages: Cell inner membrane
messages: Mediates magnesium influx to the cytosol.

272568:GDIA RS17580
gene id: 272568:GDIA_RS17580
uniprot id: A9HHM0
names: Similarity
messages: Belongs to the GSP E family.

272568:GDIA RS00630
gene id: 272568:GDIA_RS00630
uniprot id: B5ZJY2
names: Similarity
messages: Belongs to the UDPGP type 2 family.

272568:GDIA RS04580
gene id: 272568:GDIA_RS04580
uniprot id: A9HQ09
names: Similarity
messages: Belongs to the DapA family.

272568:GDIA RS10065
gene id: 272568:GDIA_RS10065
uniprot id: A9HEG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

272568:GDIA RS02200
gene id: 272568:GDIA_RS02200
uniprot id: B5ZCG7
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

272568:GDIA RS17965
gene id: 272568:GDIA_RS17965
uniprot id: B5ZMA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
messages: Cell inner membrane

272568:GDIA RS02215
gene id: 272568:GDIA_RS02215
uniprot id: A9HLG5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

272568:GDIA RS15170
gene id: 272568:GDIA_RS15170
uniprot id: A9H391
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

272568:GDIA RS03775
gene id: 272568:GDIA_RS03775
uniprot id: A9HNM8
names: Subcellular Location Annotation
messages: Membrane

272568:GDIA RS07640
gene id: 272568:GDIA_RS07640
uniprot id: A9H664
names: Similarity
messages: Belongs to the glycosyl hydrolase 68 family.

272568:GDIA RS16570
gene id: 272568:GDIA_RS16570
uniprot id: A9HS12
names: Subcellular Location Annotation
messages: Membrane

272568:GDIA RS06960
gene id: 272568:GDIA_RS06960
uniprot id: A9H8M1
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

272568:GDIA RS06615
gene id: 272568:GDIA_RS06615
uniprot id: A9H977
names: Subcellular Location Annotation
messages: Membrane

272568:GDIA RS14555
gene id: 272568:GDIA_RS14555
uniprot id: B5ZI98
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.

272568:GDIA RS02320
gene id: 272568:GDIA_RS02320
uniprot id: A9HLL7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

272568:GDIA RS08190
gene id: 272568:GDIA_RS08190
uniprot id: A9GZU0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

272568:GDIA RS02705
gene id: 272568:GDIA_RS02705
uniprot id: B5ZD97
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the spermidine/spermine synthase family.
messages: Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

272568:GDIA RS06545
gene id: 272568:GDIA_RS06545
uniprot id: A9H9A6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

272568:GDIA RS00015
gene id: 272568:GDIA_RS00015
uniprot id: A9HI34
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

272568:GDIA RS03055
gene id: 272568:GDIA_RS03055
uniprot id: B5ZDT0
names: Similarity
messages: Belongs to the peptidase M29 family.

272568:GDIA RS15240
gene id: 272568:GDIA_RS15240
uniprot id: A9H1M3
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

272568:GDIA RS07555
gene id: 272568:GDIA_RS07555
uniprot id: B5ZIQ1
names: Caution
names: Function
names: Similarity
messages: Belongs to the globin family. Two-domain flavohemoproteins subfamily.
messages: In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
messages: Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

272568:GDIA RS11820
gene id: 272568:GDIA_RS11820
uniprot id: B5ZF53
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

272568:GDIA RS09880
gene id: 272568:GDIA_RS09880
uniprot id: B5ZCR1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a global negative controlling element, employing Fe(2+) as a cofactor to bind the operator of the repressed genes.
messages: Belongs to the Fur family.
messages: Cytoplasm
messages: Homodimer.

272568:GDIA RS00635
gene id: 272568:GDIA_RS00635
uniprot id: B5ZJY3
names: Similarity
messages: Belongs to the phosphohexose mutase family.

272568:GDIA RS10490
gene id: 272568:GDIA_RS10490
uniprot id: B5ZDL2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

272568:GDIA RS15215
gene id: 272568:GDIA_RS15215
uniprot id: A9H1N8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

272568:GDIA RS07980
gene id: 272568:GDIA_RS07980
uniprot id: A9H5L8
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

272568:GDIA RS16835
gene id: 272568:GDIA_RS16835
uniprot id: B5ZLD5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.
messages: Cell membrane
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

272568:GDIA RS07030
gene id: 272568:GDIA_RS07030
uniprot id: B5ZI50
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

272568:GDIA RS12610
gene id: 272568:GDIA_RS12610
uniprot id: B5ZFU4
names: Similarity
messages: Belongs to the RecJ family.

272568:GDIA RS16645
gene id: 272568:GDIA_RS16645
uniprot id: A9HRX5
names: Similarity
messages: Belongs to the HesB/IscA family.

272568:GDIA RS01480
gene id: 272568:GDIA_RS01480
uniprot id: A9HK92
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecB family.
messages: Cytoplasm
messages: Homotetramer, a dimer of dimers. One homotetramer interacts with 1 SecA dimer.
messages: One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.

272568:GDIA RS03710
gene id: 272568:GDIA_RS03710
uniprot id: B5ZEF3
names: Subcellular Location Annotation
messages: Membrane

272568:GDIA RS08705
gene id: 272568:GDIA_RS08705
uniprot id: B5ZKX9
names: Similarity
messages: Belongs to the RelE toxin family.

272568:GDIA RS00935
gene id: 272568:GDIA_RS00935
uniprot id: A9HJF5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

272568:GDIA RS08970
gene id: 272568:GDIA_RS08970
uniprot id: A9GZI2
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

272568:GDIA RS04975
gene id: 272568:GDIA_RS04975
uniprot id: B5ZFY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TrbI/VirB10 family.
messages: Membrane

272568:GDIA RS16740
gene id: 272568:GDIA_RS16740
uniprot id: A9HRT9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

272568:GDIA RS17420
gene id: 272568:GDIA_RS17420
uniprot id: B5ZM83
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliF family.
messages: Membrane
messages: The M ring may be actively involved in energy transduction.

272568:GDIA RS17335
gene id: 272568:GDIA_RS17335
uniprot id: A9HH75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliR/MopE/SpaR family.
messages: Membrane

272568:GDIA RS00415
gene id: 272568:GDIA_RS00415
uniprot id: A9HIP5
names: Similarity
messages: Belongs to the UPF0047 family.

272568:GDIA RS01640
gene id: 272568:GDIA_RS01640
uniprot id: A9HKI7
names: Similarity
messages: Belongs to the prokaryotic GSH synthase family.

272568:GDIA RS06950
gene id: 272568:GDIA_RS06950
uniprot id: B5ZI35
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Cytoplasm
messages: Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.

272568:GDIA RS17760
gene id: 272568:GDIA_RS17760
uniprot id: B5ZD24
names: Subcellular Location Annotation
messages: Membrane

272568:GDIA RS14300
gene id: 272568:GDIA_RS14300
uniprot id: B5ZHV4
names: Subcellular Location Annotation
messages: Cell inner membrane

272568:GDIA RS14280
gene id: 272568:GDIA_RS14280
uniprot id: B5ZHV0
names: Similarity
messages: Belongs to the SCO1/2 family.

272568:GDIA RS10700
gene id: 272568:GDIA_RS10700
uniprot id: B5ZDZ9
names: Similarity
messages: Belongs to the virb1 family.

272568:GDIA RS15120
gene id: 272568:GDIA_RS15120
uniprot id: B5ZIV5
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

272568:GDIA RS13340
gene id: 272568:GDIA_RS13340
uniprot id: A9H9I9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
messages: Belongs to the azoreductase type 1 family.
messages: Binds 1 FMN per subunit.
messages: Homodimer.
messages: Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones.

272568:GDIA RS10025
gene id: 272568:GDIA_RS10025
uniprot id: A9HEE4
names: Cofactor
names: Function
messages: Accepts electrons from ETF and reduces ubiquinone.
messages: Binds 1 [4Fe-4S] cluster.

272568:GDIA RS00140
gene id: 272568:GDIA_RS00140
uniprot id: A9HI96
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

272568:GDIA RS11395
gene id: 272568:GDIA_RS11395
uniprot id: A9H2B7
names: Subcellular Location Annotation
messages: Membrane

272568:GDIA RS10910
gene id: 272568:GDIA_RS10910
uniprot id: B5ZE38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

272568:GDIA RS09510
gene id: 272568:GDIA_RS09510
uniprot id: A9HDL8
names: Subcellular Location Annotation
messages: Membrane

272568:GDIA RS14285
gene id: 272568:GDIA_RS14285
uniprot id: B5ZHV1
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

272568:GDIA RS06555
gene id: 272568:GDIA_RS06555
uniprot id: A9H9A1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase delta chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

272568:GDIA RS17385
gene id: 272568:GDIA_RS17385
uniprot id: A9HHA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliJ family.
messages: Cell membrane
messages: Membrane

272568:GDIA RS14405
gene id: 272568:GDIA_RS14405
uniprot id: B5ZHX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Cell inner membrane
messages: Membrane

272568:GDIA RS03495
gene id: 272568:GDIA_RS03495
uniprot id: B5ZEA9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

272568:GDIA RS09945
gene id: 272568:GDIA_RS09945
uniprot id: A9HEA1
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

272568:GDIA RS17130
gene id: 272568:GDIA_RS17130
uniprot id: B5ZM32
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

272568:GDIA RS15665
gene id: 272568:GDIA_RS15665
uniprot id: B5ZJQ4
names: Function
names: Similarity
names: Subunit
messages: APS kinase catalyzes the synthesis of activated sulfate.
messages: Belongs to the APS kinase family.
messages: Catalyzes the synthesis of activated sulfate.
messages: In the C-terminal section; belongs to the APS kinase family.
messages: In the N-terminal section; belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
messages: Proposed to provide activated sulfate for transfer to Nod factor. ATP sulfurylase may be the GTPase, regulating ATP sulfurylase activity.
messages: Sulfate-activating enzymes, NodP and NodQ, may be physically associated.

272568:GDIA RS00325
gene id: 272568:GDIA_RS00325
uniprot id: A9HIK2
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

272568:GDIA RS05820
gene id: 272568:GDIA_RS05820
uniprot id: A9HBA9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

272568:GDIA RS09240
gene id: 272568:GDIA_RS09240
uniprot id: A9HH12
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

272568:GDIA RS07620
gene id: 272568:GDIA_RS07620
uniprot id: A9H675
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A24 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Plays an essential role in type IV pili and type II pseudopili formation by proteolytically removing the leader sequence from substrate proteins and subsequently monomethylating the alpha-amino group of the newly exposed N-terminal phenylalanine.

272568:GDIA RS15750
gene id: 272568:GDIA_RS15750
uniprot id: A9H0R5
names: Function
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.

272568:GDIA RS00950
gene id: 272568:GDIA_RS00950
uniprot id: B5ZK44
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

272568:GDIA RS00835
gene id: 272568:GDIA_RS00835
uniprot id: B5ZK23
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.

272568:GDIA RS01280
gene id: 272568:GDIA_RS01280
uniprot id: A9HJX6
names: Subcellular Location Annotation
messages: Membrane

272568:GDIA RS02435
gene id: 272568:GDIA_RS02435
uniprot id: A9HLS1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

272568:GDIA RS10415
gene id: 272568:GDIA_RS10415
uniprot id: A9HF10
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

272568:GDIA RS00570
gene id: 272568:GDIA_RS00570
uniprot id: A9HIY5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

272568:GDIA RS10080
gene id: 272568:GDIA_RS10080
uniprot id: A9HEH3
names: Similarity
messages: Belongs to the pyruvate kinase family.

272568:GDIA RS15150
gene id: 272568:GDIA_RS15150
uniprot id: A9H3A3
names: Similarity
messages: Belongs to the peptidase S41A family.

272568:GDIA RS17065
gene id: 272568:GDIA_RS17065
uniprot id: B5ZM19
names: Function
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Catalyzes the conversion of 7,8-dihydroneopterin triphosphate (H2NTP) to 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) and acetaldehyde.

272568:GDIA RS17830
gene id: 272568:GDIA_RS17830
uniprot id: A9HI04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial glucokinase family.
messages: Cytoplasm

272568:GDIA RS16745
gene id: 272568:GDIA_RS16745
uniprot id: B5ZLB7
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

272568:GDIA RS00215
gene id: 272568:GDIA_RS00215
uniprot id: B5ZJ65
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

272568:GDIA RS15990
gene id: 272568:GDIA_RS15990
uniprot id: A9H0F1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

272568:GDIA RS07235
gene id: 272568:GDIA_RS07235
uniprot id: B5ZII6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the ABC transporter complex (TC 3.A.1.6.1) involved in sulfate/thiosulfate import.
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

272568:GDIA RS10635
gene id: 272568:GDIA_RS10635
uniprot id: A9HFE6
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

272568:GDIA RS09260
gene id: 272568:GDIA_RS09260
uniprot id: A9H1J2
names: Function
names: Similarity
messages: Belongs to the transposase 11 family.
messages: Involved in the transposition of the insertion sequence IS5.

272568:GDIA RS11850
gene id: 272568:GDIA_RS11850
uniprot id: B5ZF59
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Belongs to the transaldolase family. Type 2 subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

272568:GDIA RS04940
gene id: 272568:GDIA_RS04940
uniprot id: B5ZFX6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

272568:GDIA RS04105
gene id: 272568:GDIA_RS04105
uniprot id: A9HPA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

272568:GDIA RS16765
gene id: 272568:GDIA_RS16765
uniprot id: A9HRS9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

272568:GDIA RS07295
gene id: 272568:GDIA_RS07295
uniprot id: A9H855
names: Similarity
messages: Belongs to the disproportionating enzyme family.

272568:GDIA RS06000
gene id: 272568:GDIA_RS06000
uniprot id: B5ZH24
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

272568:GDIA RS00660
gene id: 272568:GDIA_RS00660
uniprot id: B5ZJY8
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.

272568:GDIA RS17365
gene id: 272568:GDIA_RS17365
uniprot id: A9HH92
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

272568:GDIA RS17740
gene id: 272568:GDIA_RS17740
uniprot id: A9HHV2
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

272568:GDIA RS00265
gene id: 272568:GDIA_RS00265
uniprot id: A9HIG5
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

272568:GDIA RS06090
gene id: 272568:GDIA_RS06090
uniprot id: A9HAT0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family.
messages: Membrane

272568:GDIA RS17105
gene id: 272568:GDIA_RS17105
uniprot id: B5ZM27
names: Similarity
messages: Belongs to the peptidase M13 family.

272568:GDIA RS14905
gene id: 272568:GDIA_RS14905
uniprot id: A9H3P5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

272568:GDIA RS01385
gene id: 272568:GDIA_RS01385
uniprot id: A9HK34
names: Subcellular Location Annotation
messages: Cytoplasm

272568:GDIA RS15730
gene id: 272568:GDIA_RS15730
uniprot id: A9H0S3
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

272568:GDIA RS09910
gene id: 272568:GDIA_RS09910
uniprot id: A9HE84
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

272568:GDIA RS06990
gene id: 272568:GDIA_RS06990
uniprot id: A9H8K2
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

272568:GDIA RS09535
gene id: 272568:GDIA_RS09535
uniprot id: A9HDN1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase A chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.

272568:GDIA RS15205
gene id: 272568:GDIA_RS15205
uniprot id: A9H1P4
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

272568:GDIA RS10010
gene id: 272568:GDIA_RS10010
uniprot id: A9HED6
names: Similarity
messages: Belongs to the OmpW/AlkL family.

272568:GDIA RS10995
gene id: 272568:GDIA_RS10995
uniprot id: A9HFY5
names: Cofactor
names: Similarity
messages: Belongs to the WrbA family.
messages: Binds 1 FMN per monomer.

272568:GDIA RS05770
gene id: 272568:GDIA_RS05770
uniprot id: A9HBE0
names: Cofactor
messages: Binds 3 heme c groups covalently per subunit.

272568:GDIA RS15970
gene id: 272568:GDIA_RS15970
uniprot id: B5ZKD9
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

272568:GDIA RS10235
gene id: 272568:GDIA_RS10235
uniprot id: B5ZDG0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Cytoplasm

272568:GDIA RS14640
gene id: 272568:GDIA_RS14640
uniprot id: A9H459
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS1 family.
messages: Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.

272568:GDIA RS07045
gene id: 272568:GDIA_RS07045
uniprot id: B5ZI53
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

272568:GDIA RS11035
gene id: 272568:GDIA_RS11035
uniprot id: A9HG08
names: Subcellular Location Annotation
messages: Membrane

272568:GDIA RS00245
gene id: 272568:GDIA_RS00245
uniprot id: B5ZJ71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

272568:GDIA RS15740
gene id: 272568:GDIA_RS15740
uniprot id: B5ZJR8
names: Subcellular Location Annotation
messages: Membrane

272568:GDIA RS12290
gene id: 272568:GDIA_RS12290
uniprot id: B5ZFM8
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

272568:GDIA RS07815
gene id: 272568:GDIA_RS07815
uniprot id: A9H5X4
names: Function
names: Similarity
messages: Belongs to the NifD/NifK/NifE/NifN family.
messages: This protein may play a role in the biosynthesis of the prosthetic group of nitrogenase (FeMo cofactor).

272568:GDIA RS06015
gene id: 272568:GDIA_RS06015
uniprot id: B5ZH27
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TolB family.
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: Periplasm
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

272568:GDIA RS08240
gene id: 272568:GDIA_RS08240
uniprot id: B5ZK58
names: Similarity
messages: Belongs to the DprA/Smf family.

272568:GDIA RS09385
gene id: 272568:GDIA_RS09385
uniprot id: A9HDF3
names: Subcellular Location Annotation
messages: Membrane

272568:GDIA RS10260
gene id: 272568:GDIA_RS10260
uniprot id: B5ZDG6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the OMP decarboxylase family. Type 1 subfamily.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
messages: Homodimer.

272568:GDIA RS16030
gene id: 272568:GDIA_RS16030
uniprot id: B5ZKF0
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family.

272568:GDIA RS11875
gene id: 272568:GDIA_RS11875
uniprot id: A9H335
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

272568:GDIA RS15245
gene id: 272568:GDIA_RS15245
uniprot id: A9H1M0
names: Similarity
messages: Belongs to the CFA/CMAS family.

272568:GDIA RS13625
gene id: 272568:GDIA_RS13625
uniprot id: A9H1J2
names: Function
names: Similarity
messages: Belongs to the transposase 11 family.
messages: Involved in the transposition of the insertion sequence IS5.

272568:GDIA RS06400
gene id: 272568:GDIA_RS06400
uniprot id: B5ZHI8
names: Similarity
messages: Belongs to the virb1 family.

272568:GDIA RS00100
gene id: 272568:GDIA_RS00100
uniprot id: B5ZJ42
names: Subcellular Location Annotation
messages: Membrane

272568:GDIA RS16800
gene id: 272568:GDIA_RS16800
uniprot id: B5ZLC8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 2 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
messages: Cytoplasm
messages: Homodimer.

272568:GDIA RS02975
gene id: 272568:GDIA_RS02975
uniprot id: B5ZDR4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family.
messages: Membrane

272568:GDIA RS15255
gene id: 272568:GDIA_RS15255
uniprot id: B5ZIY3
names: Similarity
messages: Belongs to the PpiC/parvulin rotamase family.

272568:GDIA RS14305
gene id: 272568:GDIA_RS14305
uniprot id: B5ZHV5
names: Subcellular Location Annotation
messages: Cell inner membrane

272568:GDIA RS02895
gene id: 272568:GDIA_RS02895
uniprot id: B5ZDP7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase E/G family. RNase E subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per homotetramer.
messages: Cell inner membrane
messages: Cytoplasm
messages: Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs.
messages: Homotetramer formed by a dimer of dimers.

272568:GDIA RS07125
gene id: 272568:GDIA_RS07125
uniprot id: A9H8C8
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

272568:GDIA RS11880
gene id: 272568:GDIA_RS11880
uniprot id: A9H338
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose 5-phosphate isomerase family.
messages: Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
messages: Homodimer.

272568:GDIA RS17880
gene id: 272568:GDIA_RS17880
uniprot id: A9HI27
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).

272568:GDIA RS06055
gene id: 272568:GDIA_RS06055
uniprot id: B5ZH35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

272568:GDIA RS03655
gene id: 272568:GDIA_RS03655
uniprot id: A9HNG8
names: Subcellular Location Annotation
messages: Membrane

272568:GDIA RS09215
gene id: 272568:GDIA_RS09215
uniprot id: A9HGZ9
names: Subcellular Location Annotation
messages: Membrane

272568:GDIA RS01415
gene id: 272568:GDIA_RS01415
uniprot id: B5ZKW3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
messages: Catalyzes the reversible phosphorylation of S-methyl-5'-thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.
messages: Homohexamer. Dimer of a homotrimer.

272568:GDIA RS17520
gene id: 272568:GDIA_RS17520
uniprot id: B5ZCX8
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

272568:GDIA RS17870
gene id: 272568:GDIA_RS17870
uniprot id: B5ZD45
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

272568:GDIA RS14425
gene id: 272568:GDIA_RS14425
uniprot id: A9H4K8
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

272568:GDIA RS12860
gene id: 272568:GDIA_RS12860
uniprot id: B5ZG94
names: Similarity
messages: Belongs to the GroES chaperonin family.

272568:GDIA RS03360
gene id: 272568:GDIA_RS03360
uniprot id: A9HN04
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

272568:GDIA RS15900
gene id: 272568:GDIA_RS15900
uniprot id: A9H0J3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

272568:GDIA RS04510
gene id: 272568:GDIA_RS04510
uniprot id: B5ZFF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

272568:GDIA RS01500
gene id: 272568:GDIA_RS01500
uniprot id: A9HKA3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RlmJ family.
messages: Monomer.
messages: Specifically methylates the adenine in position 2030 of 23S rRNA.

272568:GDIA RS09985
gene id: 272568:GDIA_RS09985
uniprot id: A9HEC1
names: Function
names: Similarity
messages: Belongs to the PqqC family.
messages: Ring cyclization and eight-electron oxidation of 3a-(2-amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline-7,9-dicarboxylic-acid to PQQ.

272568:GDIA RS07335
gene id: 272568:GDIA_RS07335
uniprot id: B5ZIK6
names: Similarity
messages: Belongs to the bacterial PQQ dehydrogenase family.

272568:GDIA RS01920
gene id: 272568:GDIA_RS01920
uniprot id: A9HKY5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

272568:GDIA RS16760
gene id: 272568:GDIA_RS16760
uniprot id: A9HRT1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

272568:GDIA RS16755
gene id: 272568:GDIA_RS16755
uniprot id: A9HRT3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the complex I 75 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

272568:GDIA RS07105
gene id: 272568:GDIA_RS07105
uniprot id: A9H8D6
names: Subcellular Location Annotation
messages: Cytoplasm

272568:GDIA RS14965
gene id: 272568:GDIA_RS14965
uniprot id: A9H3K9
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

272568:GDIA RS13580
gene id: 272568:GDIA_RS13580
uniprot id: A9HA08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

272568:GDIA RS00700
gene id: 272568:GDIA_RS00700
uniprot id: A9HJ48
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

272568:GDIA RS09175
gene id: 272568:GDIA_RS09175
uniprot id: B5ZLQ6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

272568:GDIA RS06570
gene id: 272568:GDIA_RS06570
uniprot id: B5ZHM1
names: Subcellular Location Annotation
messages: Membrane

272568:GDIA RS11295
gene id: 272568:GDIA_RS11295
uniprot id: A9H271
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic Ku family.
messages: Homodimer. Interacts with LigD.
messages: With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD.

272568:GDIA RS03515
gene id: 272568:GDIA_RS03515
uniprot id: A9HN90
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

272568:GDIA RS16520
gene id: 272568:GDIA_RS16520
uniprot id: B5ZL76
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

272568:GDIA RS03490
gene id: 272568:GDIA_RS03490
uniprot id: A9HN78
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

272568:GDIA RS10485
gene id: 272568:GDIA_RS10485
uniprot id: A9HF52
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

272568:GDIA RS09850
gene id: 272568:GDIA_RS09850
uniprot id: A9HE52
names: Function
names: Similarity
messages: Belongs to the SELO family.
messages: Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).

272568:GDIA RS10220
gene id: 272568:GDIA_RS10220
uniprot id: A9HEP7
names: Function
names: Similarity
messages: Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PDRP subfamily.
messages: Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation.

272568:GDIA RS05985
gene id: 272568:GDIA_RS05985
uniprot id: A9HB20
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

272568:GDIA RS11085
gene id: 272568:GDIA_RS11085
uniprot id: B5ZE73
names: Similarity
messages: Belongs to the dihydropyrimidine dehydrogenase family.

272568:GDIA RS00085
gene id: 272568:GDIA_RS00085
uniprot id: B5ZJ40
names: Cofactor
messages: Binds 3 heme c groups covalently per subunit.

272568:GDIA RS17775
gene id: 272568:GDIA_RS17775
uniprot id: B5ZD27
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

272568:GDIA RS09600
gene id: 272568:GDIA_RS09600
uniprot id: B5ZLY9
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

272568:GDIA RS10805
gene id: 272568:GDIA_RS10805
uniprot id: B5ZE17
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Catalyzes the deamination of dCTP to dUTP.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

272568:GDIA RS14940
gene id: 272568:GDIA_RS14940
uniprot id: A9H3M4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

272568:GDIA RS09295
gene id: 272568:GDIA_RS09295
uniprot id: A9HDA8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

272568:GDIA RS02385
gene id: 272568:GDIA_RS02385
uniprot id: B5ZCK5
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

272568:GDIA RS14630
gene id: 272568:GDIA_RS14630
uniprot id: A9H466
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

272568:GDIA RS01575
gene id: 272568:GDIA_RS01575
uniprot id: B5ZLH6
names: Similarity
messages: Belongs to the threonine synthase family.

272568:GDIA RS09315
gene id: 272568:GDIA_RS09315
uniprot id: A9HDB8
names: Similarity
messages: Belongs to the IMPACT family.

272568:GDIA RS10130
gene id: 272568:GDIA_RS10130
uniprot id: A9HEJ7
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

272568:GDIA RS05200
gene id: 272568:GDIA_RS05200
uniprot id: B5ZG33
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

272568:GDIA RS15425
gene id: 272568:GDIA_RS15425
uniprot id: A9H1B6
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

272568:GDIA RS07625
gene id: 272568:GDIA_RS07625
uniprot id: B5ZIR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP G family.
messages: Cell inner membrane
messages: Membrane

272568:GDIA RS02625
gene id: 272568:GDIA_RS02625
uniprot id: A9HM30
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

272568:GDIA RS05470
gene id: 272568:GDIA_RS05470
uniprot id: A9HBW5
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

272568:GDIA RS04065
gene id: 272568:GDIA_RS04065
uniprot id: B5ZEX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

272568:GDIA RS03220
gene id: 272568:GDIA_RS03220
uniprot id: B5ZDW0
names: Similarity
messages: Belongs to the glycosyl hydrolase 66 family.

272568:GDIA RS02835
gene id: 272568:GDIA_RS02835
uniprot id: B5ZDD6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

272568:GDIA RS05045
gene id: 272568:GDIA_RS05045
uniprot id: B5ZG01
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

272568:GDIA RS08270
gene id: 272568:GDIA_RS08270
uniprot id: A9GZP1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

272568:GDIA RS11690
gene id: 272568:GDIA_RS11690
uniprot id: B5ZF29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

272568:GDIA RS08700
gene id: 272568:GDIA_RS08700
uniprot id: B5ZKX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VirD4/TraG family.
messages: Membrane

272568:GDIA RS01295
gene id: 272568:GDIA_RS01295
uniprot id: A9HJY3
names: Similarity
messages: Belongs to the peptidase M17 family.

272568:GDIA RS12140
gene id: 272568:GDIA_RS12140
uniprot id: B5ZFB0
names: Subcellular Location Annotation
messages: Membrane

272568:GDIA RS10120
gene id: 272568:GDIA_RS10120
uniprot id: A9HEJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Essential cell division protein that coordinates cell division and chromosome segregation. The N-terminus is involved in assembly of the cell-division machinery. The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the dif recombination site, which is located within the replication terminus region. Translocation stops specifically at Xer-dif sites, where FtsK interacts with the Xer recombinase, allowing activation of chromosome unlinking by recombination. FtsK orienting polar sequences (KOPS) guide the direction of DNA translocation. FtsK can remove proteins from DNA as it translocates, but translocation stops specifically at XerCD-dif site, thereby preventing removal of XerC and XerD from dif.
messages: Homohexamer. Forms a ring that surrounds DNA.
messages: Membrane

272568:GDIA RS01645
gene id: 272568:GDIA_RS01645
uniprot id: B5ZLJ0
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family. GreB subfamily.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length.

272568:GDIA RS16275
gene id: 272568:GDIA_RS16275
uniprot id: B5ZKJ7
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

272568:GDIA RS05415
gene id: 272568:GDIA_RS05415
uniprot id: A9HBZ3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

272568:GDIA RS16370
gene id: 272568:GDIA_RS16370
uniprot id: A9HSA2
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

272568:GDIA RS00565
gene id: 272568:GDIA_RS00565
uniprot id: B5ZJX0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

272568:GDIA RS07825
gene id: 272568:GDIA_RS07825
uniprot id: A9H5W8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NifD/NifK/NifE/NifN family.
messages: Binds 1 [8Fe-7S] cluster per heterodimer.
messages: Tetramer of two alpha and two beta chains. Forms complex with the iron protein (nitrogenase component 2).
messages: This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation.

272568:GDIA RS10045
gene id: 272568:GDIA_RS10045
uniprot id: A9HEF4
names: Function
messages: Multidrug efflux pump.

272568:GDIA RS06800
gene id: 272568:GDIA_RS06800
uniprot id: B5ZI05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

272568:GDIA RS14365
gene id: 272568:GDIA_RS14365
uniprot id: B5ZHW7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

272568:GDIA RS01805
gene id: 272568:GDIA_RS01805
uniprot id: A9HKS1
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

272568:GDIA RS00780
gene id: 272568:GDIA_RS00780
uniprot id: A9HJ79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

272568:GDIA RS16410
gene id: 272568:GDIA_RS16410
uniprot id: B5ZKM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

272568:GDIA RS03255
gene id: 272568:GDIA_RS03255
uniprot id: B5ZDW8
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

272568:GDIA RS02845
gene id: 272568:GDIA_RS02845
uniprot id: B5ZDD8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. MrdB/RodA subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell wall elongation.

272568:GDIA RS15085
gene id: 272568:GDIA_RS15085
uniprot id: A9H3D9
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

272568:GDIA RS05720
gene id: 272568:GDIA_RS05720
uniprot id: B5ZGM4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I fumarase family.
messages: Catalyzes the reversible hydration of fumarate to (S)-malate.
messages: Homodimer.

272568:GDIA RS01765
gene id: 272568:GDIA_RS01765
uniprot id: A9HKP7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

272568:GDIA RS13660
gene id: 272568:GDIA_RS13660
uniprot id: A9HA51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

272568:GDIA RS16470
gene id: 272568:GDIA_RS16470
uniprot id: A9HS54
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

272568:GDIA RS00975
gene id: 272568:GDIA_RS00975
uniprot id: B5ZK49
names: Function
names: Subcellular Location Annotation
messages: Could be a virulence factor.
messages: Membrane
messages: Secreted

272568:GDIA RS12425
gene id: 272568:GDIA_RS12425
uniprot id: B5ZFQ6
names: Similarity
messages: Belongs to the GroES chaperonin family.

272568:GDIA RS11755
gene id: 272568:GDIA_RS11755
uniprot id: A9H2W1
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.

272568:GDIA RS03730
gene id: 272568:GDIA_RS03730
uniprot id: B5ZEF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

272568:GDIA RS07745
gene id: 272568:GDIA_RS07745
uniprot id: A9H605
names: Function
names: Similarity
messages: Could be a 3Fe-4S cluster-containing protein.
messages: To ferredoxins from P.putida and C.tartarivorum, ferredoxin I from A.vinelandii, ferredoxin II from D.desulfuricans.

272568:GDIA RS13405
gene id: 272568:GDIA_RS13405
uniprot id: A9H9N2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

272568:GDIA RS01230
gene id: 272568:GDIA_RS01230
uniprot id: A9HJV7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell outer membrane
messages: CyaE is necessary for transport of calmodulin-sensitive adenylate cyclase-hemolysin (cyclolysin).

272568:GDIA RS06180
gene id: 272568:GDIA_RS06180
uniprot id: B5ZH60
names: Function
names: Similarity
messages: Belongs to the catalase family.
messages: Decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide.

272568:GDIA RS04225
gene id: 272568:GDIA_RS04225
uniprot id: B5ZF04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

272568:GDIA RS14955
gene id: 272568:GDIA_RS14955
uniprot id: A9H3L5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

272568:GDIA RS08520
gene id: 272568:GDIA_RS08520
uniprot id: B5ZKA7
names: Similarity
messages: Belongs to the pirin family.

272568:GDIA RS05730
gene id: 272568:GDIA_RS05730
uniprot id: A9HBG1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidylate synthase ThyX family.
messages: Binds 4 FAD per tetramer. Each FAD binding site is formed by three monomers.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

272568:GDIA RS01815
gene id: 272568:GDIA_RS01815
uniprot id: A9HKS8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

272568:GDIA RS01175
gene id: 272568:GDIA_RS01175
uniprot id: B5ZKR5
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20 family.
messages: Binds 2 Zn(2+) ions per subunit.

272568:GDIA RS15705
gene id: 272568:GDIA_RS15705
uniprot id: B5ZJR2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MetX family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

272568:GDIA RS11725
gene id: 272568:GDIA_RS11725
uniprot id: B5ZF34
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.

272568:GDIA RS04185
gene id: 272568:GDIA_RS04185
uniprot id: A9HPE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

272568:GDIA RS08575
gene id: 272568:GDIA_RS08575
uniprot id: B5ZKB9
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

272568:GDIA RS05965
gene id: 272568:GDIA_RS05965
uniprot id: A9HB30
names: Similarity
names: Subunit
messages: Belongs to the aldehyde dehydrogenase family.
messages: Homotetramer.

272568:GDIA RS00260
gene id: 272568:GDIA_RS00260
uniprot id: A9HIG3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaE family.
messages: Converts molybdopterin precursor Z into molybdopterin. This requires the incorporation of two sulfur atoms into precursor Z to generate a dithiolene group. The sulfur is provided by MoaD.
messages: Heterotetramer of 2 MoaD subunits and 2 MoaE subunits. Also stable as homodimer. The enzyme changes between these two forms during catalysis.

272568:GDIA RS02690
gene id: 272568:GDIA_RS02690
uniprot id: A9HM50
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

272568:GDIA RS14185
gene id: 272568:GDIA_RS14185
uniprot id: B5ZHT4
names: Similarity
messages: Belongs to the TrbL/VirB6 family.

272568:GDIA RS04125
gene id: 272568:GDIA_RS04125
uniprot id: A9HPB2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

272568:GDIA RS02510
gene id: 272568:GDIA_RS02510
uniprot id: A9HLW5
names: Function
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.
messages: DNA-dependent ATPase that plays important roles in cellular responses to stalled DNA replication processes.

272568:GDIA RS04295
gene id: 272568:GDIA_RS04295
uniprot id: B5ZF18
names: Subcellular Location Annotation
messages: Membrane

272568:GDIA RS14290
gene id: 272568:GDIA_RS14290
uniprot id: A9H4S8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

272568:GDIA RS17180
gene id: 272568:GDIA_RS17180
uniprot id: A9HRC8
names: Subcellular Location Annotation
messages: Membrane

272568:GDIA RS12115
gene id: 272568:GDIA_RS12115
uniprot id: A9H543
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PNT beta subunit family.
messages: Cell inner membrane
messages: Membrane
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

272568:GDIA RS13480
gene id: 272568:GDIA_RS13480
uniprot id: A5YJ14
names: Subcellular Location Annotation
messages: Cytoplasm

272568:GDIA RS15670
gene id: 272568:GDIA_RS15670
uniprot id: A9H0V9
names: Similarity
messages: Belongs to the PAPS reductase family. CysD subfamily.

272568:GDIA RS15135
gene id: 272568:GDIA_RS15135
uniprot id: B5ZIV8
names: Subcellular Location Annotation
messages: Membrane

272568:GDIA RS14535
gene id: 272568:GDIA_RS14535
uniprot id: B5ZI95
names: Similarity
messages: Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.

272568:GDIA RS01655
gene id: 272568:GDIA_RS01655
uniprot id: A9HKJ6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

272568:GDIA RS13160
gene id: 272568:GDIA_RS13160
uniprot id: B5ZGP2
names: Similarity
messages: Belongs to the glycosyl hydrolase 32 family.

272568:GDIA RS13800
gene id: 272568:GDIA_RS13800
uniprot id: A9H6Y0
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

272568:GDIA RS01855
gene id: 272568:GDIA_RS01855
uniprot id: B5ZLN1
names: Similarity
messages: Belongs to the Skp family.

272568:GDIA RS15860
gene id: 272568:GDIA_RS15860
uniprot id: B5ZJT9
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

272568:GDIA RS17500
gene id: 272568:GDIA_RS17500
uniprot id: A9HHH1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgH family.
messages: Cell outer membrane
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

272568:GDIA RS01725
gene id: 272568:GDIA_RS01725
uniprot id: B5ZLK5
names: Function
names: Similarity
messages: Belongs to the sigma-54 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

272568:GDIA RS07720
gene id: 272568:GDIA_RS07720
uniprot id: A9H619
names: Function
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. S-2-haloalkanoic acid dehalogenase family.
messages: Catalyzes the hydrolytic dehalogenation of small (S)-2-haloalkanoic acids to yield the corresponding (R)-2-hydroxyalkanoic acids.

272568:GDIA RS16770
gene id: 272568:GDIA_RS16770
uniprot id: A9HRS8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

272568:GDIA RS17585
gene id: 272568:GDIA_RS17585
uniprot id: B5ZCZ0
names: Subcellular Location Annotation
messages: Membrane

272568:GDIA RS15865
gene id: 272568:GDIA_RS15865
uniprot id: B5ZJU0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamD family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

272568:GDIA RS14440
gene id: 272568:GDIA_RS14440
uniprot id: A9H4J9
names: Subcellular Location Annotation
messages: Membrane

272568:GDIA RS11475
gene id: 272568:GDIA_RS11475
uniprot id: A9H2G4
names: Subcellular Location Annotation
messages: Membrane

272568:GDIA RS07870
gene id: 272568:GDIA_RS07870
uniprot id: B5ZJF6
names: Function
names: Subunit
messages: Interacts with sigma-54.
messages: Required for activation of most nif operons, which are directly involved in nitrogen fixation.

272568:GDIA RS14995
gene id: 272568:GDIA_RS14995
uniprot id: A9H3I9
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

272568:GDIA RS00745
gene id: 272568:GDIA_RS00745
uniprot id: A9HJ62
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

272568:GDIA RS10575
gene id: 272568:GDIA_RS10575
uniprot id: A9HFB8
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

272568:GDIA RS16480
gene id: 272568:GDIA_RS16480
uniprot id: A9HS49
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

272568:GDIA RS06145
gene id: 272568:GDIA_RS06145
uniprot id: B5ZH52
names: Function
names: Similarity
names: Subunit
messages: Belongs to the trans-sulfuration enzymes family. MetZ subfamily.
messages: Catalyzes the formation of L-homocysteine from O-succinyl-L-homoserine (OSHS) and hydrogen sulfide.
messages: Homotetramer.

272568:GDIA RS06175
gene id: 272568:GDIA_RS06175
uniprot id: B5ZH59
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

272568:GDIA RS02730
gene id: 272568:GDIA_RS02730
uniprot id: A9HM68
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

272568:GDIA RS09715
gene id: 272568:GDIA_RS09715
uniprot id: B5ZCN0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

272568:GDIA RS02110
gene id: 272568:GDIA_RS02110
uniprot id: A9HLA2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

272568:GDIA RS06035
gene id: 272568:GDIA_RS06035
uniprot id: A9HAZ2
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

272568:GDIA RS09765
gene id: 272568:GDIA_RS09765
uniprot id: B5ZCN8
names: Function
names: Similarity
messages: Belongs to the ParB family.
messages: Involved in chromosome partition. Localize to both poles of the predivisional cell following completion of DNA replication. Binds to the DNA origin of replication.

272568:GDIA RS16070
gene id: 272568:GDIA_RS16070
uniprot id: B5ZKF8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

272568:GDIA RS09710
gene id: 272568:GDIA_RS09710
uniprot id: A9HDX7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.

272568:GDIA RS10345
gene id: 272568:GDIA_RS10345
uniprot id: B5ZDI3
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

272568:GDIA RS10365
gene id: 272568:GDIA_RS10365
uniprot id: B5ZDI7
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

272568:GDIA RS11940
gene id: 272568:GDIA_RS11940
uniprot id: A9H377
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial microcompartment
messages: Belongs to the EutC family.
messages: Binds between the large and small subunits.
messages: Catalyzes the deamination of various vicinal amino-alcohols to oxo compounds. Allows this organism to utilize ethanolamine as the sole source of nitrogen and carbon in the presence of external vitamin B12.
messages: The basic unit is a heterodimer which dimerizes to form tetramers. The heterotetramers trimerize; 6 large subunits form a core ring with 6 small subunits projecting outwards.

272568:GDIA RS17785
gene id: 272568:GDIA_RS17785
uniprot id: B5ZD29
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

272568:GDIA RS16530
gene id: 272568:GDIA_RS16530
uniprot id: B5ZL78
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

272568:GDIA RS09785
gene id: 272568:GDIA_RS09785
uniprot id: A9HE16
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.

272568:GDIA RS09975
gene id: 272568:GDIA_RS09975
uniprot id: A9HEB6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. PqqE family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the cross-linking of a glutamate residue and a tyrosine residue in the PqqA protein as part of the biosynthesis of pyrroloquinoline quinone (PQQ).
messages: Interacts with PqqD. The interaction is necessary for activity of PqqE.

272568:GDIA RS00445
gene id: 272568:GDIA_RS00445
uniprot id: A9HIR0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

272568:GDIA RS03575
gene id: 272568:GDIA_RS03575
uniprot id: B5ZEC5
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

272568:GDIA RS00060
gene id: 272568:GDIA_RS00060
uniprot id: A9HI56
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

272568:GDIA RS09340
gene id: 272568:GDIA_RS09340
uniprot id: B5ZLT7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell inner membrane
messages: Membrane

272568:GDIA RS16035
gene id: 272568:GDIA_RS16035
uniprot id: B5ZKF1
names: Similarity
messages: Belongs to the GST superfamily.

272568:GDIA RS00330
gene id: 272568:GDIA_RS00330
uniprot id: B5ZJ88
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

272568:GDIA RS09530
gene id: 272568:GDIA_RS09530
uniprot id: A9HDM8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase C chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.

272568:GDIA RS08115
gene id: 272568:GDIA_RS08115
uniprot id: A9GZY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

272568:GDIA RS17135
gene id: 272568:GDIA_RS17135
uniprot id: A9HRD8
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

272568:GDIA RS05510
gene id: 272568:GDIA_RS05510
uniprot id: B5ZGI2
names: Function
names: Similarity
messages: Belongs to the trehalose phosphatase family.
messages: Removes the phosphate from trehalose 6-phosphate to produce free trehalose.

272568:GDIA RS16400
gene id: 272568:GDIA_RS16400
uniprot id: A9HS88
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

272568:GDIA RS15295
gene id: 272568:GDIA_RS15295
uniprot id: B5ZIZ1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

272568:GDIA RS09555
gene id: 272568:GDIA_RS09555
uniprot id: B5ZLY0
names: Function
messages: Acts on leucine, isoleucine and valine.

272568:GDIA RS07910
gene id: 272568:GDIA_RS07910
uniprot id: B5ZJG4
names: Function
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Has multiple catalytic activities. Apart from catalyzing the oxidation of (+)-tartrate to oxaloglycolate, also converts meso-tartrate to D-glycerate and catalyzes the oxidative decarboxylation of D-malate to pyruvate.

272568:GDIA RS17085
gene id: 272568:GDIA_RS17085
uniprot id: A9HRF1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

272568:GDIA RS17810
gene id: 272568:GDIA_RS17810
uniprot id: A9HHZ2
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

272568:GDIA RS16985
gene id: 272568:GDIA_RS16985
uniprot id: A9HRI2
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

272568:GDIA RS03310
gene id: 272568:GDIA_RS03310
uniprot id: A9HMX6
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

272568:GDIA RS07430
gene id: 272568:GDIA_RS07430
uniprot id: B5ZIM5
names: Function
names: Similarity
messages: Belongs to the AMP nucleosidase family.
messages: Catalyzes the hydrolysis of the N-glycosidic bond of AMP to form adenine and ribose 5-phosphate. Involved in regulation of AMP concentrations.

272568:GDIA RS17745
gene id: 272568:GDIA_RS17745
uniprot id: A9HHV5
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

272568:GDIA RS02550
gene id: 272568:GDIA_RS02550
uniprot id: B5ZD67
names: Subcellular Location Annotation
messages: Membrane

272568:GDIA RS03390
gene id: 272568:GDIA_RS03390
uniprot id: A9HN22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

272568:GDIA RS11855
gene id: 272568:GDIA_RS11855
uniprot id: A9H324
names: Similarity
messages: Belongs to the 6-phosphogluconate dehydrogenase family.

272568:GDIA RS16020
gene id: 272568:GDIA_RS16020
uniprot id: B5ZKE8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia.

272568:GDIA RS15435
gene id: 272568:GDIA_RS15435
uniprot id: B5ZJ19
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

272568:GDIA RS13530
gene id: 272568:GDIA_RS13530
uniprot id: B5ZGW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane

272568:GDIA RS09525
gene id: 272568:GDIA_RS09525
uniprot id: A9HDM7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell inner membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

272568:GDIA RS14815
gene id: 272568:GDIA_RS14815
uniprot id: A9H3U0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

272568:GDIA RS00045
gene id: 272568:GDIA_RS00045
uniprot id: A9HI49
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

272568:GDIA RS00145
gene id: 272568:GDIA_RS00145
uniprot id: A9HI97
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

272568:GDIA RS17725
gene id: 272568:GDIA_RS17725
uniprot id: A9HHU1
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

272568:GDIA RS15565
gene id: 272568:GDIA_RS15565
uniprot id: B5ZJN4
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

272568:GDIA RS17350
gene id: 272568:GDIA_RS17350
uniprot id: B5ZM70
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

272568:GDIA RS00705
gene id: 272568:GDIA_RS00705
uniprot id: A9HJ49
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

272568:GDIA RS05875
gene id: 272568:GDIA_RS05875
uniprot id: B5ZGZ8
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 2 family.

272568:GDIA RS00750
gene id: 272568:GDIA_RS00750
uniprot id: A9HJ64
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

272568:GDIA RS04270
gene id: 272568:GDIA_RS04270
uniprot id: B5ZF13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nlpA lipoprotein family.
messages: Membrane

272568:GDIA RS15500
gene id: 272568:GDIA_RS15500
uniprot id: A9H170
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

272568:GDIA RS09725
gene id: 272568:GDIA_RS09725
uniprot id: B5ZCN1
names: Subcellular Location Annotation
messages: Membrane

272568:GDIA RS05905
gene id: 272568:GDIA_RS05905
uniprot id: A9HB61
names: Subcellular Location Annotation
messages: Membrane

272568:GDIA RS00985
gene id: 272568:GDIA_RS00985
uniprot id: A9HJI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

272568:GDIA RS16750
gene id: 272568:GDIA_RS16750
uniprot id: A9HRT4
names: Function
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

272568:GDIA RS16465
gene id: 272568:GDIA_RS16465
uniprot id: B5ZL65
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

272568:GDIA RS17825
gene id: 272568:GDIA_RS17825
uniprot id: B5ZD37
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

272568:GDIA RS03530
gene id: 272568:GDIA_RS03530
uniprot id: A9HN98
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

272568:GDIA RS02195
gene id: 272568:GDIA_RS02195
uniprot id: A9HLF3
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

272568:GDIA RS04755
gene id: 272568:GDIA_RS04755
uniprot id: B5ZFJ5
names: Subcellular Location Annotation
messages: Membrane

272568:GDIA RS13645
gene id: 272568:GDIA_RS13645
uniprot id: B5ZH82
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

272568:GDIA RS15010
gene id: 272568:GDIA_RS15010
uniprot id: A9H3I2
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

272568:GDIA RS06985
gene id: 272568:GDIA_RS06985
uniprot id: A9H8K5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

272568:GDIA RS02670
gene id: 272568:GDIA_RS02670
uniprot id: Q288C8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

272568:GDIA RS13425
gene id: 272568:GDIA_RS13425
uniprot id: A9H9P5
names: Subcellular Location Annotation
messages: Membrane

272568:GDIA RS01810
gene id: 272568:GDIA_RS01810
uniprot id: B5ZLM1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell inner membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

272568:GDIA RS07760
gene id: 272568:GDIA_RS07760
uniprot id: A9H5Z7
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

272568:GDIA RS03385
gene id: 272568:GDIA_RS03385
uniprot id: A9HN20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

272568:GDIA RS12765
gene id: 272568:GDIA_RS12765
uniprot id: A9H743
names: Similarity
messages: Belongs to the ArsC family.

272568:GDIA RS01355
gene id: 272568:GDIA_RS01355
uniprot id: B5ZKV1
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 2 residues (Tyr-65 and Arg-68) present in a large hydrophobic pocket are probably involved in substrate specificity. They are important for desuccinylation activity, but dispensable for deacetylation activity.
messages: Belongs to the sirtuin family. Class III subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form.

272568:GDIA RS10060
gene id: 272568:GDIA_RS10060
uniprot id: B5ZCU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

272568:GDIA RS18015
gene id: 272568:GDIA_RS18015
uniprot id: B5ZMB4
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

272568:GDIA RS14565
gene id: 272568:GDIA_RS14565
uniprot id: B5ZIA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

272568:GDIA RS03505
gene id: 272568:GDIA_RS03505
uniprot id: A9HN86
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

272568:GDIA RS09415
gene id: 272568:GDIA_RS09415
uniprot id: A9HDG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

272568:GDIA RS15995
gene id: 272568:GDIA_RS15995
uniprot id: A9H0E8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

272568:GDIA RS01515
gene id: 272568:GDIA_RS01515
uniprot id: A9HKB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.
messages: Membrane

272568:GDIA RS00485
gene id: 272568:GDIA_RS00485
uniprot id: A9HIT0
names: Subcellular Location Annotation
messages: Membrane

272568:GDIA RS04045
gene id: 272568:GDIA_RS04045
uniprot id: B5ZEW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 1 family.
messages: Periplasm

272568:GDIA RS16700
gene id: 272568:GDIA_RS16700
uniprot id: A9HRV3
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

272568:GDIA RS00460
gene id: 272568:GDIA_RS00460
uniprot id: A9HIR8
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

272568:GDIA RS02930
gene id: 272568:GDIA_RS02930
uniprot id: A9HMD4
names: Similarity
names: Subunit
messages: Belongs to the P(II) protein family.
messages: Homotrimer.

272568:GDIA RS07830
gene id: 272568:GDIA_RS07830
uniprot id: A9H5W5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NifD/NifK/NifE/NifN family.
messages: Tetramer of two alpha and two beta chains. Forms complex with the iron protein (nitrogenase component 2).
messages: This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation.

272568:GDIA RS01520
gene id: 272568:GDIA_RS01520
uniprot id: A9HKB6
names: Similarity
messages: Belongs to the glutathione peroxidase family.

272568:GDIA RS06645
gene id: 272568:GDIA_RS06645
uniprot id: A9H960
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-C family. DnaE2 subfamily.
messages: Cytoplasm
messages: DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase.

272568:GDIA RS13490
gene id: 272568:GDIA_RS13490
uniprot id: B5ZGV9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

272568:GDIA RS03340
gene id: 272568:GDIA_RS03340
uniprot id: A9HMZ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the threonine aldolase family.
messages: Catalyzes the cleavage of L-allo-threonine and L-threonine to glycine and acetaldehyde.
messages: Homotetramer.

272568:GDIA RS00050
gene id: 272568:GDIA_RS00050
uniprot id: B5ZJ33
names: Similarity
messages: Belongs to the DAMOX/DASOX family.

272568:GDIA RS17425
gene id: 272568:GDIA_RS17425
uniprot id: A9HHC5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: Cell inner membrane
messages: FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

272568:GDIA RS01535
gene id: 272568:GDIA_RS01535
uniprot id: A9HKC5
names: Activity Regulation
names: Caution
names: Domain
names: Function
names: Similarity
messages: Belongs to the GlnD family.
messages: Has four distinct domains: an N-terminal nucleotidyltransferase (NT) domain responsible for UTase activity, a central HD domain that encodes UR activity, and two C-terminal ACT domains that seem to have a role in glutamine sensing.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen fixation and metabolism.
messages: Uridylyltransferase (UTase) activity is inhibited by glutamine, while glutamine activates uridylyl-removing (UR) activity.

272568:GDIA RS05390
gene id: 272568:GDIA_RS05390
uniprot id: B5ZGF9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

272568:GDIA RS01670
gene id: 272568:GDIA_RS01670
uniprot id: A9HKK6
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

272568:GDIA RS01375
gene id: 272568:GDIA_RS01375
uniprot id: A9HK29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

272568:GDIA RS03365
gene id: 272568:GDIA_RS03365
uniprot id: A9HN07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

272568:GDIA RS04280
gene id: 272568:GDIA_RS04280
uniprot id: A9HPK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

272568:GDIA RS08830
gene id: 272568:GDIA_RS08830
uniprot id: A9HCY6
names: Similarity
messages: Belongs to the RelE toxin family.

272568:GDIA RS14135
gene id: 272568:GDIA_RS14135
uniprot id: B5ZHS4
names: Similarity
messages: Belongs to the class-A beta-lactamase family.

272568:GDIA RS08805
gene id: 272568:GDIA_RS08805
uniprot id: A9HCX4
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

272568:GDIA RS15945
gene id: 272568:GDIA_RS15945
uniprot id: A9H0G9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

272568:GDIA RS09300
gene id: 272568:GDIA_RS09300
uniprot id: A9HDB1
names: Function
names: Similarity
names: Subunit
messages: Catalyzes the ADP transfer from ATP to D-glycero-beta-D-manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose.
messages: Catalyzes the phosphorylation of D-glycero-D-manno-heptose 7-phosphate at the C-1 position to selectively form D-glycero-beta-D-manno-heptose-1,7-bisphosphate.
messages: Homodimer.
messages: In the C-terminal section; belongs to the cytidylyltransferase family.
messages: In the N-terminal section; belongs to the carbohydrate kinase PfkB family.

272568:GDIA RS04205
gene id: 272568:GDIA_RS04205
uniprot id: B5ZF00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OprB family.
messages: Cell outer membrane

272568:GDIA RS11945
gene id: 272568:GDIA_RS11945
uniprot id: A9H4U8
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

272568:GDIA RS17090
gene id: 272568:GDIA_RS17090
uniprot id: A9HRF0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

272568:GDIA RS09900
gene id: 272568:GDIA_RS09900
uniprot id: B5ZCR5
names: Function
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.
messages: Functions in two distinct reactions of the de novo folate biosynthetic pathway. Catalyzes the addition of a glutamate residue to dihydropteroate (7,8-dihydropteroate or H2Pte) to form dihydrofolate (7,8-dihydrofolate monoglutamate or H2Pte-Glu). Also catalyzes successive additions of L-glutamate to tetrahydrofolate or 10-formyltetrahydrofolate or 5,10-methylenetetrahydrofolate, leading to folylpolyglutamate derivatives.

272568:GDIA RS07215
gene id: 272568:GDIA_RS07215
uniprot id: B5ZI86
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

272568:GDIA RS01430
gene id: 272568:GDIA_RS01430
uniprot id: A9HK65
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the aerobic coproporphyrinogen-III oxidase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX.

272568:GDIA RS14750
gene id: 272568:GDIA_RS14750
uniprot id: A9H3Y4
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

272568:GDIA RS12655
gene id: 272568:GDIA_RS12655
uniprot id: B5ZFV3
names: Subcellular Location Annotation
messages: Membrane

272568:GDIA RS03485
gene id: 272568:GDIA_RS03485
uniprot id: A9HN75
names: Subcellular Location Annotation
messages: Membrane

272568:GDIA RS15510
gene id: 272568:GDIA_RS15510
uniprot id: B5ZJM2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

272568:GDIA RS17845
gene id: 272568:GDIA_RS17845
uniprot id: B5ZD40
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

272568:GDIA RS15220
gene id: 272568:GDIA_RS15220
uniprot id: B5ZIX6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

272568:GDIA RS11490
gene id: 272568:GDIA_RS11490
uniprot id: A9H2H3
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20 family.
messages: Binds 2 Zn(2+) ions per subunit.

272568:GDIA RS05835
gene id: 272568:GDIA_RS05835
uniprot id: A9HBA0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell inner membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

272568:GDIA RS00815
gene id: 272568:GDIA_RS00815
uniprot id: A9HJ97
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

272568:GDIA RS06125
gene id: 272568:GDIA_RS06125
uniprot id: B5ZH49
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.

272568:GDIA RS09330
gene id: 272568:GDIA_RS09330
uniprot id: A9HDC5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MlaE permease family.
messages: Cell inner membrane
messages: Could be part of an ABC transporter complex.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

272568:GDIA RS02695
gene id: 272568:GDIA_RS02695
uniprot id: B5ZD95
names: Similarity
messages: Belongs to the GcvT family.

272568:GDIA RS04750
gene id: 272568:GDIA_RS04750
uniprot id: B5ZFJ4
names: Similarity
messages: Belongs to the TrbG/VirB9 family.

272568:GDIA RS07305
gene id: 272568:GDIA_RS07305
uniprot id: B5ZIK0
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

272568:GDIA RS16825
gene id: 272568:GDIA_RS16825
uniprot id: B5ZLD3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

272568:GDIA RS00430
gene id: 272568:GDIA_RS00430
uniprot id: A9HIQ4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.

272568:GDIA RS17590
gene id: 272568:GDIA_RS17590
uniprot id: B5ZCZ1
names: Subcellular Location Annotation
messages: Membrane

272568:GDIA RS16585
gene id: 272568:GDIA_RS16585
uniprot id: B5ZL88
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

272568:GDIA RS04285
gene id: 272568:GDIA_RS04285
uniprot id: B5ZF16
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L-fucose isomerase family.
messages: Converts the aldose L-fucose into the corresponding ketose L-fuculose.
messages: Cytoplasm

272568:GDIA RS02950
gene id: 272568:GDIA_RS02950
uniprot id: A9HME5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S33 family.
messages: Cytoplasm

272568:GDIA RS10495
gene id: 272568:GDIA_RS10495
uniprot id: A9HF56
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

272568:GDIA RS00420
gene id: 272568:GDIA_RS00420
uniprot id: A9HIP8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

272568:GDIA RS04760
gene id: 272568:GDIA_RS04760
uniprot id: B5ZFJ6
names: Similarity
messages: Belongs to the TrbL/VirB6 family.

272568:GDIA RS14945
gene id: 272568:GDIA_RS14945
uniprot id: A9H3M1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

272568:GDIA RS07795
gene id: 272568:GDIA_RS07795
uniprot id: A9H5Y2
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

272568:GDIA RS17315
gene id: 272568:GDIA_RS17315
uniprot id: B5ZM63
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

272568:GDIA RS03180
gene id: 272568:GDIA_RS03180
uniprot id: B5ZDV5
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

272568:GDIA RS09905
gene id: 272568:GDIA_RS09905
uniprot id: A9HE81
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

272568:GDIA RS07275
gene id: 272568:GDIA_RS07275
uniprot id: A9H867
names: Similarity
messages: Belongs to the UPF0178 family.

272568:GDIA RS10790
gene id: 272568:GDIA_RS10790
uniprot id: A9HFM4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

272568:GDIA RS10530
gene id: 272568:GDIA_RS10530
uniprot id: A9HF93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

272568:GDIA RS03805
gene id: 272568:GDIA_RS03805
uniprot id: B5ZEH3
names: Subcellular Location Annotation
messages: Membrane

272568:GDIA RS02685
gene id: 272568:GDIA_RS02685
uniprot id: B5ZD93
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

272568:GDIA RS16725
gene id: 272568:GDIA_RS16725
uniprot id: A9HRU4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell inner membrane
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

272568:GDIA RS15880
gene id: 272568:GDIA_RS15880
uniprot id: B5ZJU3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell inner membrane
messages: Self-interacts. Interacts with FtsZ.

272568:GDIA RS02115
gene id: 272568:GDIA_RS02115
uniprot id: A9HLA5
names: Function
messages: Multidrug efflux pump.

272568:GDIA RS10285
gene id: 272568:GDIA_RS10285
uniprot id: A9HET5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.

272568:GDIA RS06725
gene id: 272568:GDIA_RS06725
uniprot id: B5ZHP9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

272568:GDIA RS04255
gene id: 272568:GDIA_RS04255
uniprot id: A9HPI6
names: Similarity
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Belongs to the peroxiredoxin family. Prx6 subfamily.

272568:GDIA RS07750
gene id: 272568:GDIA_RS07750
uniprot id: B5ZJD2
names: Function
names: Similarity
messages: Belongs to the ETF-QO/FixC family.
messages: Could be required for the formation of a functional nitrogenase Fe protein. Probably accepts electrons from FixA/FixB and reduces a quinone.
messages: Part of an electron transfer system.

272568:GDIA RS07685
gene id: 272568:GDIA_RS07685
uniprot id: B5ZJB9
names: Subcellular Location Annotation
messages: Cell inner membrane

272568:GDIA RS06955
gene id: 272568:GDIA_RS06955
uniprot id: A9H8M4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

272568:GDIA RS11525
gene id: 272568:GDIA_RS11525
uniprot id: B5ZEQ0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

272568:GDIA RS00270
gene id: 272568:GDIA_RS00270
uniprot id: A9HIG8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

272568:GDIA RS04590
gene id: 272568:GDIA_RS04590
uniprot id: A9HQ14
names: PTM
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.
messages: Carbamylation allows a single lysine to coordinate two divalent metal cations.

272568:GDIA RS13125
gene id: 272568:GDIA_RS13125
uniprot id: B5ZGE4
names: Subcellular Location Annotation
messages: Membrane

272568:GDIA RS15885
gene id: 272568:GDIA_RS15885
uniprot id: B5ZJU4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsQ/DivIB family. FtsQ subfamily.
messages: Cell inner membrane
messages: Essential cell division protein.

272568:GDIA RS09310
gene id: 272568:GDIA_RS09310
uniprot id: A9HDB5
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins.

272568:GDIA RS11845
gene id: 272568:GDIA_RS11845
uniprot id: B5ZF58
names: Similarity
messages: Belongs to the transketolase family.

272568:GDIA RS02830
gene id: 272568:GDIA_RS02830
uniprot id: B5ZDD5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

272568:GDIA RS08380
gene id: 272568:GDIA_RS08380
uniprot id: B5ZK80
names: Similarity
messages: Belongs to the OsmC/Ohr family.

272568:GDIA RS02205
gene id: 272568:GDIA_RS02205
uniprot id: B5ZCG8
names: Subcellular Location Annotation
messages: Mitochondrion matrix

272568:GDIA RS14960
gene id: 272568:GDIA_RS14960
uniprot id: A9H3L2
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

272568:GDIA RS15160
gene id: 272568:GDIA_RS15160
uniprot id: A9H397
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

272568:GDIA RS09840
gene id: 272568:GDIA_RS09840
uniprot id: B5ZCQ3
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

272568:GDIA RS15005
gene id: 272568:GDIA_RS15005
uniprot id: B5ZIT2
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

272568:GDIA RS15545
gene id: 272568:GDIA_RS15545
uniprot id: B5ZJN0
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

272568:GDIA RS14275
gene id: 272568:GDIA_RS14275
uniprot id: A9H4T5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
messages: Single-chain monomer with multiple functions.

272568:GDIA RS00995
gene id: 272568:GDIA_RS00995
uniprot id: A9HJI8
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

272568:GDIA RS11980
gene id: 272568:GDIA_RS11980
uniprot id: B5ZF81
names: Similarity
messages: Belongs to the band 7/mec-2 family. HflC subfamily.

272568:GDIA RS15230
gene id: 272568:GDIA_RS15230
uniprot id: A9H1N0
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

272568:GDIA RS01615
gene id: 272568:GDIA_RS01615
uniprot id: A9HPY4
names: Similarity
messages: Belongs to the transposase IS21/IS408/IS1162 family.

272568:GDIA RS08525
gene id: 272568:GDIA_RS08525
uniprot id: B5ZKA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

272568:GDIA RS11965
gene id: 272568:GDIA_RS11965
uniprot id: A9H4V7
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

272568:GDIA RS02630
gene id: 272568:GDIA_RS02630
uniprot id: A9HM31
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell inner membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

272568:GDIA RS07355
gene id: 272568:GDIA_RS07355
uniprot id: A9H821
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

272568:GDIA RS10680
gene id: 272568:GDIA_RS10680
uniprot id: A9HFH1
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

272568:GDIA RS03315
gene id: 272568:GDIA_RS03315
uniprot id: B5ZDY0
names: Function
names: Similarity
messages: Belongs to the DadA oxidoreductase family.
messages: Oxidative deamination of D-amino acids.

272568:GDIA RS04685
gene id: 272568:GDIA_RS04685
uniprot id: B5ZFI1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

272568:GDIA RS02565
gene id: 272568:GDIA_RS02565
uniprot id: B5ZD69
names: Function
names: Similarity
messages: Belongs to the anhydro-N-acetylmuramic acid kinase family.
messages: Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.

272568:GDIA RS16305
gene id: 272568:GDIA_RS16305
uniprot id: B5ZKK1
names: Similarity
names: Subunit
messages: Belongs to the methylthioribose kinase family.
messages: Homodimer.

272568:GDIA RS16245
gene id: 272568:GDIA_RS16245
uniprot id: B5ZKJ1
names: Subcellular Location Annotation
messages: Cell membrane

272568:GDIA RS15685
gene id: 272568:GDIA_RS15685
uniprot id: B5ZJQ8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
messages: Homodimer.

272568:GDIA RS17850
gene id: 272568:GDIA_RS17850
uniprot id: A9HI12
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

272568:GDIA RS02485
gene id: 272568:GDIA_RS02485
uniprot id: A9HLV5
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

272568:GDIA RS00400
gene id: 272568:GDIA_RS00400
uniprot id: A9HIN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0187 family.
messages: Membrane

272568:GDIA RS16730
gene id: 272568:GDIA_RS16730
uniprot id: A9HRU3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity).

272568:GDIA RS07570
gene id: 272568:GDIA_RS07570
uniprot id: B5ZIQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP K family.
messages: Cell inner membrane
messages: Membrane

272568:GDIA RS14975
gene id: 272568:GDIA_RS14975
uniprot id: A9H3K2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell inner membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

272568:GDIA RS08040
gene id: 272568:GDIA_RS08040
uniprot id: B5ZJI9
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

272568:GDIA RS02620
gene id: 272568:GDIA_RS02620
uniprot id: A9HM29
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

272568:GDIA RS01310
gene id: 272568:GDIA_RS01310
uniprot id: A9HJZ0
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

272568:GDIA RS16445
gene id: 272568:GDIA_RS16445
uniprot id: A9HS66
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

272568:GDIA RS05060
gene id: 272568:GDIA_RS05060
uniprot id: B5ZG04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VirD4/TraG family.
messages: Membrane

272568:GDIA RS05395
gene id: 272568:GDIA_RS05395
uniprot id: A9HC06
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

272568:GDIA RS13505
gene id: 272568:GDIA_RS13505
uniprot id: A9H9W4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

272568:GDIA RS12615
gene id: 272568:GDIA_RS12615
uniprot id: B5ZFU5
names: Similarity
messages: Belongs to the FBPase class 2 family.

272568:GDIA RS02450
gene id: 272568:GDIA_RS02450
uniprot id: B5ZCL7
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes.

272568:GDIA RS04245
gene id: 272568:GDIA_RS04245
uniprot id: A9HPH9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

272568:GDIA RS10295
gene id: 272568:GDIA_RS10295
uniprot id: B5ZDH3
names: Similarity
messages: Belongs to the peptidase U62 family.

272568:GDIA RS04810
gene id: 272568:GDIA_RS04810
uniprot id: B5ZFV4
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.

272568:GDIA RS05600
gene id: 272568:GDIA_RS05600
uniprot id: B5ZGK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ivy family.
messages: Periplasm

272568:GDIA RS00590
gene id: 272568:GDIA_RS00590
uniprot id: B5ZJX5
names: Similarity
messages: Belongs to the group II decarboxylase family.

272568:GDIA RS09930
gene id: 272568:GDIA_RS09930
uniprot id: A9HE96
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

272568:GDIA RS04690
gene id: 272568:GDIA_RS04690
uniprot id: B5ZFI2
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.

272568:GDIA RS03090
gene id: 272568:GDIA_RS03090
uniprot id: B5ZDT7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAK/KUP transporter (TC 2.A.72) family.
messages: Cell inner membrane
messages: Membrane
messages: Transport of potassium into the cell.

272568:GDIA RS04030
gene id: 272568:GDIA_RS04030
uniprot id: A9HP12
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

272568:GDIA RS01395
gene id: 272568:GDIA_RS01395
uniprot id: A9HK46
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

272568:GDIA RS09645
gene id: 272568:GDIA_RS09645
uniprot id: B5ZLZ8
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

272568:GDIA RS08225
gene id: 272568:GDIA_RS08225
uniprot id: A9GZR7
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

272568:GDIA RS15365
gene id: 272568:GDIA_RS15365
uniprot id: B5ZJ05
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

272568:GDIA RS03520
gene id: 272568:GDIA_RS03520
uniprot id: A9HN93
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

272568:GDIA RS03025
gene id: 272568:GDIA_RS03025
uniprot id: B5ZDS4
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
messages: Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Seems to participate in the biosynthesis of the nitrogenase metalloclusters by providing the inorganic sulfur required for the Fe-S core formation.

272568:GDIA RS17660
gene id: 272568:GDIA_RS17660
uniprot id: A9HHQ7
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

272568:GDIA RS01370
gene id: 272568:GDIA_RS01370
uniprot id: B5ZKV4
names: Subcellular Location Annotation
messages: Membrane

272568:GDIA RS12980
gene id: 272568:GDIA_RS12980
uniprot id: A9H7G6
names: Similarity
messages: Belongs to the bacterioferritin family.

272568:GDIA RS17655
gene id: 272568:GDIA_RS17655
uniprot id: A9HHQ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.

272568:GDIA RS06750
gene id: 272568:GDIA_RS06750
uniprot id: A9H902
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NRAMP family.
messages: Cell inner membrane
messages: H(+)-stimulated, divalent metal cation uptake system.

272568:GDIA RS06045
gene id: 272568:GDIA_RS06045
uniprot id: A9HAV7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

272568:GDIA RS04075
gene id: 272568:GDIA_RS04075
uniprot id: B5ZEX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Membrane

272568:GDIA RS07050
gene id: 272568:GDIA_RS07050
uniprot id: A9H8G8
names: Function
names: Similarity
messages: Belongs to the ribF family.
messages: Catalyzes the phosphorylation of riboflavin to FMN followed by the adenylation of FMN to FAD.

272568:GDIA RS17875
gene id: 272568:GDIA_RS17875
uniprot id: B5ZD46
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

272568:GDIA RS17885
gene id: 272568:GDIA_RS17885
uniprot id: A9HI30
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

272568:GDIA RS15905
gene id: 272568:GDIA_RS15905
uniprot id: B5ZJU8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell inner membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

272568:GDIA RS09740
gene id: 272568:GDIA_RS09740
uniprot id: B5ZCN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

272568:GDIA RS16675
gene id: 272568:GDIA_RS16675
uniprot id: A9HRW1
names: Subcellular Location Annotation
messages: Membrane

272568:GDIA RS05915
gene id: 272568:GDIA_RS05915
uniprot id: A9HB55
names: Similarity
messages: Belongs to the Dps family.

272568:GDIA RS15515
gene id: 272568:GDIA_RS15515
uniprot id: A9H162
names: Function
names: Similarity
messages: Belongs to the LpxB family.
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

272568:GDIA RS15200
gene id: 272568:GDIA_RS15200
uniprot id: A9H1P7
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

272568:GDIA RS09565
gene id: 272568:GDIA_RS09565
uniprot id: A9HDP9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

272568:GDIA RS08550
gene id: 272568:GDIA_RS08550
uniprot id: B5ZKB4
names: Similarity
messages: Belongs to the GST superfamily.

272568:GDIA RS09750
gene id: 272568:GDIA_RS09750
uniprot id: A9HDZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

272568:GDIA RS10795
gene id: 272568:GDIA_RS10795
uniprot id: A9HFM7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Lacks the C-terminal regulatory region which is replaced by HisZ.

272568:GDIA RS08250
gene id: 272568:GDIA_RS08250
uniprot id: A9GZQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

272568:GDIA RS08355
gene id: 272568:GDIA_RS08355
uniprot id: B5ZK76
names: Function
names: Similarity
messages: Belongs to the transposase 11 family.
messages: Involved in the transposition of the insertion sequence IS5.

272568:GDIA RS04900
gene id: 272568:GDIA_RS04900
uniprot id: B5ZFW9
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

272568:GDIA RS15350
gene id: 272568:GDIA_RS15350
uniprot id: A9H1G5
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain.

272568:GDIA RS06685
gene id: 272568:GDIA_RS06685
uniprot id: B5ZHP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

272568:GDIA RS07765
gene id: 272568:GDIA_RS07765
uniprot id: Q9FA11
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NifW family.
messages: Homotrimer; associates with NifD.
messages: May protect the nitrogenase Fe-Mo protein from oxidative damage.

272568:GDIA RS03545
gene id: 272568:GDIA_RS03545
uniprot id: B5ZEB9
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

272568:GDIA RS07920
gene id: 272568:GDIA_RS07920
uniprot id: B5ZJG6
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

272568:GDIA RS02445
gene id: 272568:GDIA_RS02445
uniprot id: A9HLS6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

272568:GDIA RS13550
gene id: 272568:GDIA_RS13550
uniprot id: A9H9Z3
names: Similarity
messages: Belongs to the ABC transporter superfamily.

272568:GDIA RS02185
gene id: 272568:GDIA_RS02185
uniprot id: A9HLE8
names: Similarity
messages: Belongs to the class-II DAHP synthase family.

272568:GDIA RS02880
gene id: 272568:GDIA_RS02880
uniprot id: A9HMA2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homotetramer.

272568:GDIA RS13780
gene id: 272568:GDIA_RS13780
uniprot id: B5ZHA8
names: Function
messages: Involved in the transposition of the insertion sequence.

272568:GDIA RS13785
gene id: 272568:GDIA_RS13785
uniprot id: B5ZEJ1
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

272568:GDIA RS14200
gene id: 272568:GDIA_RS14200
uniprot id: B5ZHT7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TrbI/VirB10 family.
messages: Membrane

272568:GDIA RS14170
gene id: 272568:GDIA_RS14170
uniprot id: B5ZHT1
names: Similarity
messages: Belongs to the TrbE/VirB4 family.

272568:GDIA RS03795
gene id: 272568:GDIA_RS03795
uniprot id: A9HNN4
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

272568:GDIA RS08210
gene id: 272568:GDIA_RS08210
uniprot id: B5ZK52
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

272568:GDIA RS16880
gene id: 272568:GDIA_RS16880
uniprot id: B5ZLE2
names: Similarity
messages: Belongs to the DEAD box helicase family.

272568:GDIA RS16690
gene id: 272568:GDIA_RS16690
uniprot id: A9HRV7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

272568:GDIA RS01180
gene id: 272568:GDIA_RS01180
uniprot id: A9HJT9
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

272568:GDIA RS07775
gene id: 272568:GDIA_RS07775
uniprot id: P57794
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
messages: Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Seems to participate in the biosynthesis of the nitrogenase metalloclusters by providing the inorganic sulfur required for the Fe-S core formation.
messages: Homodimer.

272568:GDIA RS11455
gene id: 272568:GDIA_RS11455
uniprot id: B5ZEN6
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

272568:GDIA RS14585
gene id: 272568:GDIA_RS14585
uniprot id: A9H4B0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

272568:GDIA RS07130
gene id: 272568:GDIA_RS07130
uniprot id: A9H8C5
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

272568:GDIA RS09935
gene id: 272568:GDIA_RS09935
uniprot id: A9HE98
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

272568:GDIA RS08945
gene id: 272568:GDIA_RS08945
uniprot id: A9GZG8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

272568:GDIA RS14225
gene id: 272568:GDIA_RS14225
uniprot id: B5ZHU0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An FAD-requiring monooxygenase active on some tetracycline antibiotic derivatives, which leads to their inactivation. Hydroxylates carbon 11a of tetracycline and some analogs.
messages: Belongs to the aromatic-ring hydroxylase family. TetX subfamily.
messages: Consists of an N-terminal FAD-binding domain with a Rossman fold and a C-terminal substrate-binding domain.
messages: Cytoplasm
messages: Monomer.

272568:GDIA RS05805
gene id: 272568:GDIA_RS05805
uniprot id: A9HBC0
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

272568:GDIA RS02055
gene id: 272568:GDIA_RS02055
uniprot id: B5ZCD7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

272568:GDIA RS15595
gene id: 272568:GDIA_RS15595
uniprot id: B5ZJP0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family.
messages: Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.
messages: Cell inner membrane

272568:GDIA RS13835
gene id: 272568:GDIA_RS13835
uniprot id: B5ZHB8
names: Similarity
messages: Belongs to the Gfa family.

272568:GDIA RS00720
gene id: 272568:GDIA_RS00720
uniprot id: A9HJ52
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

272568:GDIA RS01075
gene id: 272568:GDIA_RS01075
uniprot id: A9HJN5
names: Similarity
messages: Belongs to the UPF0758 family.

272568:GDIA RS05375
gene id: 272568:GDIA_RS05375
uniprot id: A9HC19
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

272568:GDIA RS09550
gene id: 272568:GDIA_RS09550
uniprot id: A9HDN9
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

272568:GDIA RS17435
gene id: 272568:GDIA_RS17435
uniprot id: A9HHD1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliN/MopA/SpaO family.
messages: Cell membrane
messages: FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

272568:GDIA RS06030
gene id: 272568:GDIA_RS06030
uniprot id: A9HAZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbB/TolQ family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

272568:GDIA RS14610
gene id: 272568:GDIA_RS14610
uniprot id: A9H477
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

272568:GDIA RS05665
gene id: 272568:GDIA_RS05665
uniprot id: B5ZGL3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.
messages: In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: In the N-terminal section; belongs to the MIP18 family.

272568:GDIA RS07785
gene id: 272568:GDIA_RS07785
uniprot id: A9H5Y5
names: Similarity
messages: Belongs to the HesB/IscA family.

272568:GDIA RS10325
gene id: 272568:GDIA_RS10325
uniprot id: B5ZDH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell inner membrane
messages: Membrane

272568:GDIA RS11385
gene id: 272568:GDIA_RS11385
uniprot id: B5ZEM2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

272568:GDIA RS00210
gene id: 272568:GDIA_RS00210
uniprot id: A9HID1
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

272568:GDIA RS12045
gene id: 272568:GDIA_RS12045
uniprot id: A9H502
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

272568:GDIA RS06795
gene id: 272568:GDIA_RS06795
uniprot id: B5ZI04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

272568:GDIA RS06075
gene id: 272568:GDIA_RS06075
uniprot id: A9HAT8
names: Subcellular Location Annotation
messages: Membrane

272568:GDIA RS07425
gene id: 272568:GDIA_RS07425
uniprot id: A9H7Y3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

272568:GDIA RS13120
gene id: 272568:GDIA_RS13120
uniprot id: B5ZGE3
names: Subcellular Location Annotation
messages: Membrane

272568:GDIA RS12035
gene id: 272568:GDIA_RS12035
uniprot id: B5ZF90
names: Similarity
messages: Belongs to the OprB family.

272568:GDIA RS15290
gene id: 272568:GDIA_RS15290
uniprot id: A9H1J6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inositol monophosphatase superfamily. CysQ family.
messages: Cell inner membrane
messages: Converts adenosine-3',5'-bisphosphate (PAP) to AMP.

272568:GDIA RS15015
gene id: 272568:GDIA_RS15015
uniprot id: A9H3H9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

272568:GDIA RS10630
gene id: 272568:GDIA_RS10630
uniprot id: B5ZDN9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

272568:GDIA RS11150
gene id: 272568:GDIA_RS11150
uniprot id: A9HG78
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell inner membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

272568:GDIA RS07780
gene id: 272568:GDIA_RS07780
uniprot id: A9H5Y7
names: Function
names: Similarity
messages: Belongs to the NifU family.
messages: May be involved in the formation or repair of [Fe-S] clusters present in iron-sulfur proteins.

272568:GDIA RS14620
gene id: 272568:GDIA_RS14620
uniprot id: A9H473
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

272568:GDIA RS16695
gene id: 272568:GDIA_RS16695
uniprot id: A9HRV4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

272568:GDIA RS01255
gene id: 272568:GDIA_RS01255
uniprot id: B5ZKT1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

272568:GDIA RS09865
gene id: 272568:GDIA_RS09865
uniprot id: A9HE60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

272568:GDIA RS16990
gene id: 272568:GDIA_RS16990
uniprot id: B5ZM03
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

272568:GDIA RS15765
gene id: 272568:GDIA_RS15765
uniprot id: B5ZJS1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily.
messages: Cell inner membrane
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Purine salvage pathway enzyme that catalyzes the transfer of the ribosyl-5-phosphate group from 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to the N9 position of the 6-oxopurines guanine and xanthine to form the corresponding ribonucleotides GMP (guanosine 5'-monophosphate) and XMP (xanthosine 5'-monophosphate), with the release of PPi. To a lesser extent, also acts on hypoxanthine.

272568:GDIA RS15075
gene id: 272568:GDIA_RS15075
uniprot id: A9H3E6
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

272568:GDIA RS13665
gene id: 272568:GDIA_RS13665
uniprot id: B5ZH86
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

272568:GDIA RS00825
gene id: 272568:GDIA_RS00825
uniprot id: A9HJA3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

272568:GDIA RS10395
gene id: 272568:GDIA_RS10395
uniprot id: A9HF00
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

272568:GDIA RS01445
gene id: 272568:GDIA_RS01445
uniprot id: A9HK73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

272568:GDIA RS14790
gene id: 272568:GDIA_RS14790
uniprot id: B5ZIE7
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

272568:GDIA RS17205
gene id: 272568:GDIA_RS17205
uniprot id: B5ZM47
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

272568:GDIA RS01970
gene id: 272568:GDIA_RS01970
uniprot id: B5ZLQ4
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

272568:GDIA RS05025
gene id: 272568:GDIA_RS05025
uniprot id: B5ZFZ5
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

272568:GDIA RS10770
gene id: 272568:GDIA_RS10770
uniprot id: B5ZE10
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA gyrase inhibitor YacG family.
messages: Binds 1 zinc ion.
messages: Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.
messages: Interacts with GyrB.

272568:GDIA RS05710
gene id: 272568:GDIA_RS05710
uniprot id: A9HBH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

272568:GDIA RS17795
gene id: 272568:GDIA_RS17795
uniprot id: A9HHY3
names: Activity Regulation
names: Caution
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

272568:GDIA RS11970
gene id: 272568:GDIA_RS11970
uniprot id: A9H4W0
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

272568:GDIA RS01145
gene id: 272568:GDIA_RS01145
uniprot id: A9HJS1
names: Similarity
messages: Belongs to the lysine N(6)-hydroxylase/L-ornithine N(5)-oxygenase family.

272568:GDIA RS03755
gene id: 272568:GDIA_RS03755
uniprot id: B5ZEG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

272568:GDIA RS06860
gene id: 272568:GDIA_RS06860
uniprot id: A9H8T6
names: Subcellular Location Annotation
messages: Membrane

272568:GDIA RS15845
gene id: 272568:GDIA_RS15845
uniprot id: B5ZJT6
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.

272568:GDIA RS00710
gene id: 272568:GDIA_RS00710
uniprot id: A9HJ50
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

272568:GDIA RS09490
gene id: 272568:GDIA_RS09490
uniprot id: B5ZLW6
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

272568:GDIA RS00680
gene id: 272568:GDIA_RS00680
uniprot id: A9HJ43
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
messages: O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.

272568:GDIA RS09115
gene id: 272568:GDIA_RS09115
uniprot id: B5ZL50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

272568:GDIA RS07095
gene id: 272568:GDIA_RS07095
uniprot id: A9H8E4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

272568:GDIA RS16780
gene id: 272568:GDIA_RS16780
uniprot id: B5ZLC4
names: Subcellular Location Annotation
messages: Membrane

272568:GDIA RS02250
gene id: 272568:GDIA_RS02250
uniprot id: B5ZCH7
names: Similarity
messages: Belongs to the HesB/IscA family.

272568:GDIA RS17805
gene id: 272568:GDIA_RS17805
uniprot id: A9HHY9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

272568:GDIA RS05400
gene id: 272568:GDIA_RS05400
uniprot id: B5ZGG1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

272568:GDIA RS03350
gene id: 272568:GDIA_RS03350
uniprot id: B5ZDY6
names: Similarity
messages: Belongs to the PhzF family.

272568:GDIA RS10420
gene id: 272568:GDIA_RS10420
uniprot id: A9HF12
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

272568:GDIA RS10525
gene id: 272568:GDIA_RS10525
uniprot id: A9HF92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

272568:GDIA RS09225
gene id: 272568:GDIA_RS09225
uniprot id: A9HH05
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

272568:GDIA RS09405
gene id: 272568:GDIA_RS09405
uniprot id: B5ZLV0
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

272568:GDIA RS05005
gene id: 272568:GDIA_RS05005
uniprot id: B5ZFZ1
names: Similarity
messages: Belongs to the TrbE/VirB4 family.

272568:GDIA RS06815
gene id: 272568:GDIA_RS06815
uniprot id: A9H8W8
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

272568:GDIA RS09825
gene id: 272568:GDIA_RS09825
uniprot id: A9HE38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

272568:GDIA RS08110
gene id: 272568:GDIA_RS08110
uniprot id: B5ZJJ6
names: Cofactor
names: Similarity
messages: Belongs to the nitroreductase family.
messages: Binds 1 FMN per subunit.

272568:GDIA RS16965
gene id: 272568:GDIA_RS16965
uniprot id: B5ZLF7
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

272568:GDIA RS08790
gene id: 272568:GDIA_RS08790
uniprot id: A9HCW3
names: Subcellular Location Annotation
messages: Membrane

272568:GDIA RS08965
gene id: 272568:GDIA_RS08965
uniprot id: B5ZL18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family.
messages: Membrane

272568:GDIA RS16950
gene id: 272568:GDIA_RS16950
uniprot id: A9HRJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF nuclease family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

272568:GDIA RS01850
gene id: 272568:GDIA_RS01850
uniprot id: A9HKU5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

272568:GDIA RS15800
gene id: 272568:GDIA_RS15800
uniprot id: B5ZJS7
names: Subcellular Location Annotation
messages: Membrane

272568:GDIA RS00185
gene id: 272568:GDIA_RS00185
uniprot id: B5ZJ59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aromatic amine dehydrogenase heavy chain family.
messages: Periplasm

272568:GDIA RS06300
gene id: 272568:GDIA_RS06300
uniprot id: A9HAG7
names: Cofactor
names: Function
messages: Binds 2 [4Fe-4S] clusters.
messages: Component of a complex that catalyzes the oxidation of glycolate to glyoxylate.

272568:GDIA RS08580
gene id: 272568:GDIA_RS08580
uniprot id: B5ZKC0
names: Subcellular Location Annotation
messages: Membrane

272568:GDIA RS07690
gene id: 272568:GDIA_RS07690
uniprot id: A9H635
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

272568:GDIA RS10255
gene id: 272568:GDIA_RS10255
uniprot id: B5ZDG5
names: Similarity
messages: Belongs to the TrpF family.

272568:GDIA RS07610
gene id: 272568:GDIA_RS07610
uniprot id: A9H681
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

272568:GDIA RS08220
gene id: 272568:GDIA_RS08220
uniprot id: A9GZS1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Monomer.

272568:GDIA RS07670
gene id: 272568:GDIA_RS07670
uniprot id: B5ZIS4
names: Similarity
messages: Belongs to the pirin family.

272568:GDIA RS16785
gene id: 272568:GDIA_RS16785
uniprot id: A9HRS3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

272568:GDIA RS09305
gene id: 272568:GDIA_RS09305
uniprot id: B5ZLT0
names: Similarity
messages: Belongs to the N-acylglucosamine 2-epimerase family.

272568:GDIA RS13390
gene id: 272568:GDIA_RS13390
uniprot id: A9H9M3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

272568:GDIA RS13335
gene id: 272568:GDIA_RS13335
uniprot id: B5ZGS6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell inner membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane

272568:GDIA RS07880
gene id: 272568:GDIA_RS07880
uniprot id: B5ZJF8
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

272568:GDIA RS15285
gene id: 272568:GDIA_RS15285
uniprot id: B5ZIY9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.

272568:GDIA RS03120
gene id: 272568:GDIA_RS03120
uniprot id: B5ZDU3
names: Subcellular Location Annotation
messages: Membrane

272568:GDIA RS14925
gene id: 272568:GDIA_RS14925
uniprot id: A9H3N4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

272568:GDIA RS03080
gene id: 272568:GDIA_RS03080
uniprot id: B5ZDT5
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

272568:GDIA RS03075
gene id: 272568:GDIA_RS03075
uniprot id: B5ZDT4
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

272568:GDIA RS09915
gene id: 272568:GDIA_RS09915
uniprot id: A9HE87
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

272568:GDIA RS09075
gene id: 272568:GDIA_RS09075
uniprot id: A9HGR9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 1 family.
messages: Periplasm

272568:GDIA RS02305
gene id: 272568:GDIA_RS02305
uniprot id: A9HLK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Membrane

272568:GDIA RS07395
gene id: 272568:GDIA_RS07395
uniprot id: B5ZIL8
names: Similarity
names: Subunit
messages: Belongs to the P(II) protein family.
messages: Homotrimer.

272568:GDIA RS11565
gene id: 272568:GDIA_RS11565
uniprot id: A9H2L4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell inner membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

272568:GDIA RS07885
gene id: 272568:GDIA_RS07885
uniprot id: A9H5S2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

272568:GDIA RS12635
gene id: 272568:GDIA_RS12635
uniprot id: A9HCR1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

272568:GDIA RS00920
gene id: 272568:GDIA_RS00920
uniprot id: B5ZK38
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

272568:GDIA RS13045
gene id: 272568:GDIA_RS13045
uniprot id: B5ZGD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

272568:GDIA RS15725
gene id: 272568:GDIA_RS15725
uniprot id: B5ZJR6
names: Similarity
messages: Belongs to the ABC transporter superfamily.

272568:GDIA RS04830
gene id: 272568:GDIA_RS04830
uniprot id: B5ZFV8
names: Similarity
messages: Belongs to the virb1 family.

272568:GDIA RS08140
gene id: 272568:GDIA_RS08140
uniprot id: A9GZW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA-PH family.
messages: Cytoplasm

272568:GDIA RS06405
gene id: 272568:GDIA_RS06405
uniprot id: A9HAA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0053 family. Hemolysin C subfamily.
messages: Membrane

272568:GDIA RS11185
gene id: 272568:GDIA_RS11185
uniprot id: A9HG97
names: Similarity
messages: Belongs to the peptidase C56 family.

272568:GDIA RS17345
gene id: 272568:GDIA_RS17345
uniprot id: A9HH80
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

272568:GDIA RS17340
gene id: 272568:GDIA_RS17340
uniprot id: A9HH78
names: Similarity
messages: Belongs to the type III secretion exporter family.

272568:GDIA RS04730
gene id: 272568:GDIA_RS04730
uniprot id: B5ZFJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

272568:GDIA RS11210
gene id: 272568:GDIA_RS11210
uniprot id: A9HGB4
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

272568:GDIA RS15020
gene id: 272568:GDIA_RS15020
uniprot id: A9H3H6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

272568:GDIA RS00960
gene id: 272568:GDIA_RS00960
uniprot id: B5ZK46
names: Similarity
messages: Belongs to the glutaredoxin family. Monothiol subfamily.

272568:GDIA RS01890
gene id: 272568:GDIA_RS01890
uniprot id: A9HKW8
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

272568:GDIA RS00155
gene id: 272568:GDIA_RS00155
uniprot id: A9HIA3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily.
messages: Cytoplasm
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

272568:GDIA RS02515
gene id: 272568:GDIA_RS02515
uniprot id: B5ZD60
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

272568:GDIA RS17025
gene id: 272568:GDIA_RS17025
uniprot id: A9HRH0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

272568:GDIA RS10675
gene id: 272568:GDIA_RS10675
uniprot id: B5ZDZ4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

272568:GDIA RS16535
gene id: 272568:GDIA_RS16535
uniprot id: A9HS25
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

272568:GDIA RS01940
gene id: 272568:GDIA_RS01940
uniprot id: A9HKZ6
names: Similarity
messages: Belongs to the MQO family.

272568:GDIA RS02955
gene id: 272568:GDIA_RS02955
uniprot id: B5ZDR0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

272568:GDIA RS08570
gene id: 272568:GDIA_RS08570
uniprot id: B5ZKB8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

272568:GDIA RS16100
gene id: 272568:GDIA_RS16100
uniprot id: A9H092
names: Similarity
messages: Belongs to the Nudix hydrolase family.

272568:GDIA RS16330
gene id: 272568:GDIA_RS16330
uniprot id: B5ZKK6
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

272568:GDIA RS02065
gene id: 272568:GDIA_RS02065
uniprot id: A9HL73
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

272568:GDIA RS11545
gene id: 272568:GDIA_RS11545
uniprot id: B5ZEQ4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

272568:GDIA RS06885
gene id: 272568:GDIA_RS06885
uniprot id: B5ZI23
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

272568:GDIA RS01580
gene id: 272568:GDIA_RS01580
uniprot id: A9HKF0
names: Similarity
messages: Belongs to the peptidase M16 family.

272568:GDIA RS01955
gene id: 272568:GDIA_RS01955
uniprot id: A9HL07
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MsrP family.
messages: Binds 1 Mo-molybdopterin (Mo-MPT) cofactor per subunit.
messages: Heterodimer of a catalytic subunit (MsrP) and a heme-binding subunit (MsrQ).
messages: Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide.
messages: Periplasm
messages: Predicted to be exported by the Tat system. The position of the signal peptide cleavage has not been experimentally proven.

272568:GDIA RS04720
gene id: 272568:GDIA_RS04720
uniprot id: B5ZFI8
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

272568:GDIA RS10800
gene id: 272568:GDIA_RS10800
uniprot id: A9HFN0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm

272568:GDIA RS04955
gene id: 272568:GDIA_RS04955
uniprot id: B5ZFY0
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

272568:GDIA RS02210
gene id: 272568:GDIA_RS02210
uniprot id: A9HLG2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.

272568:GDIA RS09390
gene id: 272568:GDIA_RS09390
uniprot id: A9HDF5
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

272568:GDIA RS10670
gene id: 272568:GDIA_RS10670
uniprot id: B5ZDZ3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-ketoglutarate dehydrogenase family.
messages: E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).
messages: Homodimer. Part of the 2-oxoglutarate dehydrogenase (OGDH) complex composed of E1 (2-oxoglutarate dehydrogenase), E2 (dihydrolipoamide succinyltransferase) and E3 (dihydrolipoamide dehydrogenase); the complex contains multiple copies of the three enzymatic components (E1, E2 and E3).

272568:GDIA RS02475
gene id: 272568:GDIA_RS02475
uniprot id: B5ZD53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP12 family.
messages: Mitochondrion

272568:GDIA RS01490
gene id: 272568:GDIA_RS01490
uniprot id: A9HK97
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

272568:GDIA RS16090
gene id: 272568:GDIA_RS16090
uniprot id: B5ZKG2
names: Subcellular Location Annotation
messages: Membrane

272568:GDIA RS05815
gene id: 272568:GDIA_RS05815
uniprot id: A9HBB1
names: Similarity
messages: Belongs to the pirin family.

272568:GDIA RS17540
gene id: 272568:GDIA_RS17540
uniprot id: A9HHK3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: Cell inner membrane
messages: FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

272568:GDIA RS02860
gene id: 272568:GDIA_RS02860
uniprot id: A9HM95
names: Function
names: Similarity
messages: Belongs to the MreC family.
messages: Involved in formation and maintenance of cell shape.

272568:GDIA RS11040
gene id: 272568:GDIA_RS11040
uniprot id: A9HG11
names: Subcellular Location Annotation
messages: Membrane

272568:GDIA RS15680
gene id: 272568:GDIA_RS15680
uniprot id: A9H0V0
names: Similarity
messages: Belongs to the universal stress protein A family.

272568:GDIA RS17840
gene id: 272568:GDIA_RS17840
uniprot id: B5ZD39
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

272568:GDIA RS11500
gene id: 272568:GDIA_RS11500
uniprot id: A9H2H9
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

272568:GDIA RS02400
gene id: 272568:GDIA_RS02400
uniprot id: B5ZCK8
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
messages: This function is generally fulfilled by the C-terminal part of HisG, which is missing in some bacteria such as this one.

272568:GDIA RS09025
gene id: 272568:GDIA_RS09025
uniprot id: A9HPY4
names: Similarity
messages: Belongs to the transposase IS21/IS408/IS1162 family.

272568:GDIA RS14950
gene id: 272568:GDIA_RS14950
uniprot id: A9H3L8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

272568:GDIA RS02720
gene id: 272568:GDIA_RS02720
uniprot id: B5ZDA0
names: Function
names: Subunit
messages: Homotetramer.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

272568:GDIA RS02315
gene id: 272568:GDIA_RS02315
uniprot id: B5ZCJ0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

272568:GDIA RS02395
gene id: 272568:GDIA_RS02395
uniprot id: A9HLQ1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

272568:GDIA RS01795
gene id: 272568:GDIA_RS01795
uniprot id: B5ZLL8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family.
messages: Cytoplasm
messages: Homotrimer.

272568:GDIA RS05065
gene id: 272568:GDIA_RS05065
uniprot id: B5ZG05
names: Similarity
messages: Belongs to the RelE toxin family.

272568:GDIA RS09380
gene id: 272568:GDIA_RS09380
uniprot id: B5ZLU5
names: Subcellular Location Annotation
messages: Membrane

272568:GDIA RS05215
gene id: 272568:GDIA_RS05215
uniprot id: B5ZG36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CitM (TC 2.A.11) transporter family.
messages: Cell membrane
messages: Membrane

272568:GDIA RS08985
gene id: 272568:GDIA_RS08985
uniprot id: A9GZJ1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

272568:GDIA RS14810
gene id: 272568:GDIA_RS14810
uniprot id: B5ZIF1
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

272568:GDIA RS17865
gene id: 272568:GDIA_RS17865
uniprot id: A9HI21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

272568:GDIA RS00730
gene id: 272568:GDIA_RS00730
uniprot id: A9HJ55
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
messages: Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.
messages: Cytoplasm
messages: Homodimer.

272568:GDIA RS00470
gene id: 272568:GDIA_RS00470
uniprot id: A9HIS5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
messages: Cytoplasm
messages: Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.

272568:GDIA RS03445
gene id: 272568:GDIA_RS03445
uniprot id: A9HN51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0014 family.
messages: Membrane

272568:GDIA RS15875
gene id: 272568:GDIA_RS15875
uniprot id: B5ZJU2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

272568:GDIA RS10615
gene id: 272568:GDIA_RS10615
uniprot id: A9HFD7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Cell inner membrane
messages: Membrane

272568:GDIA RS10730
gene id: 272568:GDIA_RS10730
uniprot id: B5ZE05
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

272568:GDIA RS01345
gene id: 272568:GDIA_RS01345
uniprot id: B5ZKU9
names: Similarity
messages: Belongs to the bacterial PQQ dehydrogenase family.

272568:GDIA RS10645
gene id: 272568:GDIA_RS10645
uniprot id: A9HFF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CpxP/Spy family.
messages: Periplasm

272568:GDIA RS14105
gene id: 272568:GDIA_RS14105
uniprot id: B5ZHR8
names: Subcellular Location Annotation
messages: Membrane

272568:GDIA RS14360
gene id: 272568:GDIA_RS14360
uniprot id: B5ZHW6
names: Similarity
messages: Belongs to the GARS family.

272568:GDIA RS02070
gene id: 272568:GDIA_RS02070
uniprot id: A9HL77
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

272568:GDIA RS01365
gene id: 272568:GDIA_RS01365
uniprot id: A9HK24
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

272568:GDIA RS07280
gene id: 272568:GDIA_RS07280
uniprot id: A9H863
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAL/histidase family.
messages: Contains an active site 4-methylidene-imidazol-5-one (MIO), which is formed autocatalytically by cyclization and dehydration of residues Ala-Ser-Gly.
messages: Cytoplasm

272568:GDIA RS05625
gene id: 272568:GDIA_RS05625
uniprot id: B5ZGK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OpgD/OpgG family.
messages: Periplasm

272568:GDIA RS00875
gene id: 272568:GDIA_RS00875
uniprot id: A9HQE1
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

272568:GDIA RS06590
gene id: 272568:GDIA_RS06590
uniprot id: A9H988
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

272568:GDIA RS01730
gene id: 272568:GDIA_RS01730
uniprot id: A9HKN3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

272568:GDIA RS02135
gene id: 272568:GDIA_RS02135
uniprot id: B5ZCF4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

272568:GDIA RS11075
gene id: 272568:GDIA_RS11075
uniprot id: A9HG35
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

272568:GDIA RS04170
gene id: 272568:GDIA_RS04170
uniprot id: B5ZEZ3
names: Similarity
messages: Belongs to the FGGY kinase family.

272568:GDIA RS04210
gene id: 272568:GDIA_RS04210
uniprot id: B5ZF01
names: Subcellular Location Annotation
messages: Membrane

272568:GDIA RS16210
gene id: 272568:GDIA_RS16210
uniprot id: A9H073
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

272568:GDIA RS14725
gene id: 272568:GDIA_RS14725
uniprot id: B5ZID3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmC/CycZ/HelC family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

272568:GDIA RS07895
gene id: 272568:GDIA_RS07895
uniprot id: B5ZJG1
names: Function
names: Similarity
messages: Belongs to the sigma-54 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

272568:GDIA RS09925
gene id: 272568:GDIA_RS09925
uniprot id: A9HE94
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

272568:GDIA RS10835
gene id: 272568:GDIA_RS10835
uniprot id: A9HFP5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also edits incorrectly charged L-seryl-tRNA(Thr).
messages: Cytoplasm
messages: Homodimer.

272568:GDIA RS00020
gene id: 272568:GDIA_RS00020
uniprot id: B5ZJ27
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

272568:GDIA RS04190
gene id: 272568:GDIA_RS04190
uniprot id: A9HPE7
names: Similarity
messages: Belongs to the ABC transporter superfamily.

272568:GDIA RS11270
gene id: 272568:GDIA_RS11270
uniprot id: A9H259
names: Function
names: Similarity
messages: In the C-terminal section; belongs to the precorrin methyltransferase family.
messages: In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family.
messages: Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme.

272568:GDIA RS01560
gene id: 272568:GDIA_RS01560
uniprot id: A9HKD9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M32 family.
messages: Binds 1 zinc ion per subunit.
messages: Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues.

272568:GDIA RS02465
gene id: 272568:GDIA_RS02465
uniprot id: A9HLU2
names: Caution
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Belongs to the IspF family.
messages: Bifunctional enzyme that catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF).
messages: In the C-terminal section; belongs to the IspF family.
messages: In the N-terminal section; belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

272568:GDIA RS06010
gene id: 272568:GDIA_RS06010
uniprot id: A9HB05
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Pal lipoprotein family.
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

272568:GDIA RS13085
gene id: 272568:GDIA_RS13085
uniprot id: B5ZGD6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

272568:GDIA RS04530
gene id: 272568:GDIA_RS04530
uniprot id: B5ZFF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

272568:GDIA RS09920
gene id: 272568:GDIA_RS09920
uniprot id: B5ZCR9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

272568:GDIA RS05620
gene id: 272568:GDIA_RS05620
uniprot id: B5ZGK4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. OpgH subfamily.
messages: Cell inner membrane
messages: Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs).
messages: Membrane

272568:GDIA RS17075
gene id: 272568:GDIA_RS17075
uniprot id: A9HRF4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.

272568:GDIA RS07710
gene id: 272568:GDIA_RS07710
uniprot id: A9H624
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

272568:GDIA RS00175
gene id: 272568:GDIA_RS00175
uniprot id: A9HIB4
names: Similarity
messages: Belongs to the UPF0229 family.

272568:GDIA RS11860
gene id: 272568:GDIA_RS11860
uniprot id: A9H326
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

272568:GDIA RS13190
gene id: 272568:GDIA_RS13190
uniprot id: B5ZGP8
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. Nitrilase family.

272568:GDIA RS06170
gene id: 272568:GDIA_RS06170
uniprot id: B5ZH58
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

272568:GDIA RS07810
gene id: 272568:GDIA_RS07810
uniprot id: A9H5X7
names: Similarity
messages: Belongs to the NifX/NifY family.

272568:GDIA RS10840
gene id: 272568:GDIA_RS10840
uniprot id: A9HFP7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-3 family.
messages: Cytoplasm
messages: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
messages: Monomer.

272568:GDIA RS05570
gene id: 272568:GDIA_RS05570
uniprot id: B5ZGJ4
names: Similarity
messages: Belongs to the DEAD box helicase family.

272568:GDIA RS04080
gene id: 272568:GDIA_RS04080
uniprot id: B5ZEX5
names: Similarity
messages: Belongs to the SCO1/2 family.

272568:GDIA RS14825
gene id: 272568:GDIA_RS14825
uniprot id: A9H3T4
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

272568:GDIA RS07680
gene id: 272568:GDIA_RS07680
uniprot id: B5ZJB8
names: Function
names: Similarity
messages: Belongs to the catalase family.
messages: Has an organic peroxide-dependent peroxidase activity.

272568:GDIA RS16395
gene id: 272568:GDIA_RS16395
uniprot id: A9HS91
names: Similarity
messages: Belongs to the pseudomonas-type ThrB family.

272568:GDIA RS07445
gene id: 272568:GDIA_RS07445
uniprot id: B5ZIM8
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

272568:GDIA RS06050
gene id: 272568:GDIA_RS06050
uniprot id: A9HAV5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RuvC family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.

272568:GDIA RS03325
gene id: 272568:GDIA_RS03325
uniprot id: A9HPY4
names: Similarity
messages: Belongs to the transposase IS21/IS408/IS1162 family.

272568:GDIA RS16850
gene id: 272568:GDIA_RS16850
uniprot id: B5ZLD8
names: Subcellular Location Annotation
messages: Membrane

272568:GDIA RS14530
gene id: 272568:GDIA_RS14530
uniprot id: B5ZI94
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

272568:GDIA RS06065
gene id: 272568:GDIA_RS06065
uniprot id: B5ZH37
names: Similarity
messages: Belongs to the PpiC/parvulin rotamase family.

272568:GDIA RS08125
gene id: 272568:GDIA_RS08125
uniprot id: B5ZJJ9
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

272568:GDIA RS09620
gene id: 272568:GDIA_RS09620
uniprot id: A9HDT4
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

272568:GDIA RS00880
gene id: 272568:GDIA_RS00880
uniprot id: A9H1J2
names: Function
names: Similarity
messages: Belongs to the transposase 11 family.
messages: Involved in the transposition of the insertion sequence IS5.

272568:GDIA RS16735
gene id: 272568:GDIA_RS16735
uniprot id: A9HRU1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 30 kDa subunit family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

272568:GDIA RS11060
gene id: 272568:GDIA_RS11060
uniprot id: A9HG23
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

272568:GDIA RS14125
gene id: 272568:GDIA_RS14125
uniprot id: B5ZHS2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VirD4/TraG family.
messages: Membrane

272568:GDIA RS10785
gene id: 272568:GDIA_RS10785
uniprot id: A9HFM1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

272568:GDIA RS15950
gene id: 272568:GDIA_RS15950
uniprot id: A9H0G8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

272568:GDIA RS07630
gene id: 272568:GDIA_RS07630
uniprot id: A9H670
names: Similarity
messages: Belongs to the virb1 family.

272568:GDIA RS00805
gene id: 272568:GDIA_RS00805
uniprot id: A9HJ91
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

272568:GDIA RS15850
gene id: 272568:GDIA_RS15850
uniprot id: A9H0M0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0053 family. Hemolysin C subfamily.
messages: Membrane

272568:GDIA RS17185
gene id: 272568:GDIA_RS17185
uniprot id: B5ZM43
names: Subcellular Location Annotation
messages: Membrane

272568:GDIA RS03040
gene id: 272568:GDIA_RS03040
uniprot id: B5ZDS7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

272568:GDIA RS08305
gene id: 272568:GDIA_RS08305
uniprot id: A9GZM2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Cob(I)alamin adenosyltransferase family.
messages: Cytoplasm
messages: Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids.

272568:GDIA RS08825
gene id: 272568:GDIA_RS08825
uniprot id: A9HCY3
names: Similarity
messages: Belongs to the RelB/DinJ antitoxin family.

272568:GDIA RS14635
gene id: 272568:GDIA_RS14635
uniprot id: A9H463
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

272568:GDIA RS01325
gene id: 272568:GDIA_RS01325
uniprot id: B5ZKU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Membrane

272568:GDIA RS16485
gene id: 272568:GDIA_RS16485
uniprot id: A9HS47
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

272568:GDIA RS16845
gene id: 272568:GDIA_RS16845
uniprot id: A9HRP9
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

272568:GDIA RS10215
gene id: 272568:GDIA_RS10215
uniprot id: B5ZDF6
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Catalyzes the reversible phosphorylation of pyruvate and phosphate.

272568:GDIA RS15480
gene id: 272568:GDIA_RS15480
uniprot id: A9H186
names: Cofactor
messages: Binds 3 heme c groups covalently per subunit.

272568:GDIA RS15485
gene id: 272568:GDIA_RS15485
uniprot id: B5ZJL7
names: Similarity
messages: Belongs to the bacterial PQQ dehydrogenase family.

272568:GDIA RS10915
gene id: 272568:GDIA_RS10915
uniprot id: B5ZE39
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

272568:GDIA RS00955
gene id: 272568:GDIA_RS00955
uniprot id: A9HJG6
names: Similarity
messages: Belongs to the BolA/IbaG family.

272568:GDIA RS01885
gene id: 272568:GDIA_RS01885
uniprot id: A9HKW6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

272568:GDIA RS00645
gene id: 272568:GDIA_RS00645
uniprot id: B5ZJY5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer and homodimer.

272568:GDIA RS16115
gene id: 272568:GDIA_RS16115
uniprot id: B5ZKG7
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

272568:GDIA RS00240
gene id: 272568:GDIA_RS00240
uniprot id: B5ZJ70
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

272568:GDIA RS07835
gene id: 272568:GDIA_RS07835
uniprot id: Q9ZIE4
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the NifH/BchL/ChlL family.
messages: Binds 1 [4Fe-4S] cluster per dimer.
messages: Homodimer.
messages: The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein.
messages: The reversible ADP-ribosylation of Arg-102 inactivates the nitrogenase reductase and regulates nitrogenase activity.

272568:GDIA RS11305
gene id: 272568:GDIA_RS11305
uniprot id: B5ZEK7
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) per subunit.

272568:GDIA RS00410
gene id: 272568:GDIA_RS00410
uniprot id: A9HIP3
names: Function
names: Similarity
messages: Belongs to the esterase D family.
messages: Serine hydrolase involved in the detoxification of formaldehyde.

272568:GDIA RS00800
gene id: 272568:GDIA_RS00800
uniprot id: B5ZK16
names: Similarity
messages: Belongs to the PpiC/parvulin rotamase family.

272568:GDIA RS11485
gene id: 272568:GDIA_RS11485
uniprot id: A9H2H0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

272568:GDIA RS05290
gene id: 272568:GDIA_RS05290
uniprot id: B5ZGE7
names: Similarity
messages: Belongs to the RelB/DinJ antitoxin family.

272568:GDIA RS02640
gene id: 272568:GDIA_RS02640
uniprot id: B5ZD84
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.

272568:GDIA RS08980
gene id: 272568:GDIA_RS08980
uniprot id: B5ZL21
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

272568:GDIA RS01865
gene id: 272568:GDIA_RS01865
uniprot id: A9HKV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

272568:GDIA RS07110
gene id: 272568:GDIA_RS07110
uniprot id: A9H8D2
names: Function
names: Similarity
messages: Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity.
messages: Belongs to the AhpD family.

272568:GDIA RS04795
gene id: 272568:GDIA_RS04795
uniprot id: B5ZFK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VirD4/TraG family.
messages: Membrane

272568:GDIA RS09360
gene id: 272568:GDIA_RS09360
uniprot id: B5ZLU1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhD family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.

272568:GDIA RS15925
gene id: 272568:GDIA_RS15925
uniprot id: B5ZJV2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

272568:GDIA RS00620
gene id: 272568:GDIA_RS00620
uniprot id: A9HJ12
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

272568:GDIA RS15235
gene id: 272568:GDIA_RS15235
uniprot id: A9H1M6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

272568:GDIA RS06165
gene id: 272568:GDIA_RS06165
uniprot id: A9HAN8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

272568:GDIA RS05830
gene id: 272568:GDIA_RS05830
uniprot id: B5ZGY7
names: Function
names: Similarity
messages: Belongs to the CobT family.
messages: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).

272568:GDIA RS17675
gene id: 272568:GDIA_RS17675
uniprot id: A9HHR8
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

272568:GDIA RS16680
gene id: 272568:GDIA_RS16680
uniprot id: A9HRW0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

272568:GDIA RS05440
gene id: 272568:GDIA_RS05440
uniprot id: B5ZGG9
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily.
messages: Binds 1 NADP(+) per subunit.
messages: Catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose.
messages: Contains a large N-terminal NADP-binding domain, and a smaller C-terminal substrate-binding domain.
messages: Homopentamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

272568:GDIA RS06480
gene id: 272568:GDIA_RS06480
uniprot id: A9H9C7
names: Function
names: Similarity
messages: Belongs to the DadA oxidoreductase family.
messages: Oxidative deamination of D-amino acids.

272568:GDIA RS01830
gene id: 272568:GDIA_RS01830
uniprot id: A9HKT4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the glyoxalase I family.
messages: Binds 1 nickel ion per subunit.
messages: Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione.

272568:GDIA RS10155
gene id: 272568:GDIA_RS10155
uniprot id: A9HEL1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

272568:GDIA RS09320
gene id: 272568:GDIA_RS09320
uniprot id: A9HDC1
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

272568:GDIA RS07850
gene id: 272568:GDIA_RS07850
uniprot id: A9H5U1
names: Similarity
messages: Belongs to the NifZ family.

272568:GDIA RS07310
gene id: 272568:GDIA_RS07310
uniprot id: A9H846
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
messages: Monomer.

272568:GDIA RS04555
gene id: 272568:GDIA_RS04555
uniprot id: B5ZFG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

272568:GDIA RS07135
gene id: 272568:GDIA_RS07135
uniprot id: B5ZI70
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.

272568:GDIA RS17020
gene id: 272568:GDIA_RS17020
uniprot id: B5ZM10
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

272568:GDIA RS06695
gene id: 272568:GDIA_RS06695
uniprot id: A9H927
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

272568:GDIA RS15805
gene id: 272568:GDIA_RS15805
uniprot id: A9H0P2
names: Subcellular Location Annotation
messages: Membrane

272568:GDIA RS10330
gene id: 272568:GDIA_RS10330
uniprot id: A9HEW1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

272568:GDIA RS06855
gene id: 272568:GDIA_RS06855
uniprot id: A9H8U7
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

272568:GDIA RS02590
gene id: 272568:GDIA_RS02590
uniprot id: B5ZD74
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

272568:GDIA RS01705
gene id: 272568:GDIA_RS01705
uniprot id: B5ZLK1
names: Similarity
messages: Belongs to the SIS family. GutQ/KpsF subfamily.

272568:GDIA RS18100
gene id: 272568:GDIA_RS18100
uniprot id: B5ZFS7
names: Function
names: Similarity
messages: Belongs to the bacterial ice nucleation protein family.
messages: Ice nucleation proteins enable bacteria to nucleate crystallization in supercooled water.

272568:GDIA RS04735
gene id: 272568:GDIA_RS04735
uniprot id: B5ZFJ1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

272568:GDIA RS03440
gene id: 272568:GDIA_RS03440
uniprot id: B5ZE98
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the malate synthase family. GlcB subfamily.
messages: Cytoplasm
messages: Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

272568:GDIA RS09570
gene id: 272568:GDIA_RS09570
uniprot id: A9HDQ2
names: Subcellular Location Annotation
messages: Cytoplasm

272568:GDIA RS05505
gene id: 272568:GDIA_RS05505
uniprot id: A9HBU6
names: Similarity
messages: Belongs to the glycosyltransferase 20 family.

272568:GDIA RS14730
gene id: 272568:GDIA_RS14730
uniprot id: B5ZID4
names: Similarity
messages: Belongs to the YciI family.

272568:GDIA RS06935
gene id: 272568:GDIA_RS06935
uniprot id: A9H8N9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
messages: Homodimer.

272568:GDIA RS11760
gene id: 272568:GDIA_RS11760
uniprot id: A9H2W4
names: Activity Regulation
names: Caution
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

272568:GDIA RS15525
gene id: 272568:GDIA_RS15525
uniprot id: B5ZJM6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRA-CH family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
messages: Cytoplasm
messages: Homodimer.

272568:GDIA RS00850
gene id: 272568:GDIA_RS00850
uniprot id: B5ZK26
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

272568:GDIA RS17980
gene id: 272568:GDIA_RS17980
uniprot id: B5ZMA8
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

272568:GDIA RS00510
gene id: 272568:GDIA_RS00510
uniprot id: B5ZJV9
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

272568:GDIA RS17450
gene id: 272568:GDIA_RS17450
uniprot id: A9HHE0
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

272568:GDIA RS00560
gene id: 272568:GDIA_RS00560
uniprot id: A9HIX9
names: Similarity
messages: Belongs to the SdhE FAD assembly factor family.

272568:GDIA RS01910
gene id: 272568:GDIA_RS01910
uniprot id: A9HKX9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

272568:GDIA RS16055
gene id: 272568:GDIA_RS16055
uniprot id: A9H0B5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

272568:GDIA RS01770
gene id: 272568:GDIA_RS01770
uniprot id: A9HKQ2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

272568:GDIA RS08425
gene id: 272568:GDIA_RS08425
uniprot id: B5ZK88
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

272568:GDIA RS00770
gene id: 272568:GDIA_RS00770
uniprot id: A9HJ75
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

272568:GDIA RS11450
gene id: 272568:GDIA_RS11450
uniprot id: A9H2F0
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

272568:GDIA RS10350
gene id: 272568:GDIA_RS10350
uniprot id: B5ZDI4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

272568:GDIA RS02285
gene id: 272568:GDIA_RS02285
uniprot id: B5ZCI4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 90 family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Molecular chaperone. Has ATPase activity.

272568:GDIA RS11955
gene id: 272568:GDIA_RS11955
uniprot id: A9H4V1
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

272568:GDIA RS05295
gene id: 272568:GDIA_RS05295
uniprot id: B5ZGE8
names: Similarity
messages: Belongs to the RelE toxin family.

272568:GDIA RS15675
gene id: 272568:GDIA_RS15675
uniprot id: B5ZJQ6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.
messages: Cytoplasm

272568:GDIA RS06905
gene id: 272568:GDIA_RS06905
uniprot id: A9H8Q7
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

272568:GDIA RS01095
gene id: 272568:GDIA_RS01095
uniprot id: A9HJP6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

272568:GDIA RS00930
gene id: 272568:GDIA_RS00930
uniprot id: A9HJF3
names: Similarity
messages: Belongs to the SAICAR synthetase family.

272568:GDIA RS01465
gene id: 272568:GDIA_RS01465
uniprot id: A9HK84
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family. N(4) subfamily.

272568:GDIA RS16550
gene id: 272568:GDIA_RS16550
uniprot id: A9HS21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

272568:GDIA RS16380
gene id: 272568:GDIA_RS16380
uniprot id: A9HS98
names: Subcellular Location Annotation
messages: Membrane

272568:GDIA RS05970
gene id: 272568:GDIA_RS05970
uniprot id: B5ZH18
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

272568:GDIA RS00945
gene id: 272568:GDIA_RS00945
uniprot id: B5ZK43
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

272568:GDIA RS14855
gene id: 272568:GDIA_RS14855
uniprot id: A9H3R9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

272568:GDIA RS07700
gene id: 272568:GDIA_RS07700
uniprot id: B5ZJC2
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

272568:GDIA RS17890
gene id: 272568:GDIA_RS17890
uniprot id: A9HI31
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

272568:GDIA RS16805
gene id: 272568:GDIA_RS16805
uniprot id: A9HRR4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

272568:GDIA RS15645
gene id: 272568:GDIA_RS15645
uniprot id: B5ZJQ0
names: Function
messages: Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.

272568:GDIA RS06485
gene id: 272568:GDIA_RS06485
uniprot id: A9H9C5
names: Subunit
messages: Homotrimer.

272568:GDIA RS04175
gene id: 272568:GDIA_RS04175
uniprot id: A9HPE1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 1 family.
messages: Periplasm

272568:GDIA RS01125
gene id: 272568:GDIA_RS01125
uniprot id: B5ZKQ5
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20 family.
messages: Binds 2 Zn(2+) ions per subunit.

272568:GDIA RS10360
gene id: 272568:GDIA_RS10360
uniprot id: B5ZDI6
names: Subcellular Location Annotation
messages: Membrane

272568:GDIA RS00755
gene id: 272568:GDIA_RS00755
uniprot id: B5ZK07
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

272568:GDIA RS17330
gene id: 272568:GDIA_RS17330
uniprot id: A9HH72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Membrane

272568:GDIA RS07175
gene id: 272568:GDIA_RS07175
uniprot id: A9H8A2
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

272568:GDIA RS08990
gene id: 272568:GDIA_RS08990
uniprot id: A9GZJ4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.

272568:GDIA RS15055
gene id: 272568:GDIA_RS15055
uniprot id: A9H3F7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

272568:GDIA RS01270
gene id: 272568:GDIA_RS01270
uniprot id: B5ZKT4
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

272568:GDIA RS14450
gene id: 272568:GDIA_RS14450
uniprot id: A9H4J4
names: Domain
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
messages: Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.

272568:GDIA RS13730
gene id: 272568:GDIA_RS13730
uniprot id: A9H1J2
names: Function
names: Similarity
messages: Belongs to the transposase 11 family.
messages: Involved in the transposition of the insertion sequence IS5.

272568:GDIA RS16710
gene id: 272568:GDIA_RS16710
uniprot id: A9HRU7
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

272568:GDIA RS00790
gene id: 272568:GDIA_RS00790
uniprot id: A9HJ83
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

272568:GDIA RS00855
gene id: 272568:GDIA_RS00855
uniprot id: A9HJC0
names: Similarity
messages: Belongs to the ribosome association toxin RatA family.

272568:GDIA RS16045
gene id: 272568:GDIA_RS16045
uniprot id: A9H0C0
names: Similarity
messages: Belongs to the ros/MucR family.

272568:GDIA RS02990
gene id: 272568:GDIA_RS02990
uniprot id: B5ZDR7
names: Similarity
messages: Belongs to the cytochrome P450 family.

272568:GDIA RS02280
gene id: 272568:GDIA_RS02280
uniprot id: A9HLJ6
names: Function
names: Similarity
messages: Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).

272568:GDIA RS02240
gene id: 272568:GDIA_RS02240
uniprot id: B5ZCH5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

272568:GDIA RS15450
gene id: 272568:GDIA_RS15450
uniprot id: B5ZJ22
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

272568:GDIA RS14495
gene id: 272568:GDIA_RS14495
uniprot id: B5ZI88
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

272568:GDIA RS14870
gene id: 272568:GDIA_RS14870
uniprot id: A9H3R6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

272568:GDIA RS06470
gene id: 272568:GDIA_RS06470
uniprot id: A9H9C9
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the ferredoxin--NADP reductase type 2 family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

272568:GDIA RS15455
gene id: 272568:GDIA_RS15455
uniprot id: B5ZJ23
names: Similarity
messages: Belongs to the ClpX chaperone family. HslU subfamily.

272568:GDIA RS13240
gene id: 272568:GDIA_RS13240
uniprot id: B5ZGQ8
names: Similarity
messages: Belongs to the N-acylglucosamine 2-epimerase family.

272568:GDIA RS17565
gene id: 272568:GDIA_RS17565
uniprot id: A9HHL5
names: Similarity
messages: Belongs to the bacterial secretin family.

272568:GDIA RS06660
gene id: 272568:GDIA_RS06660
uniprot id: A9H954
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

272568:GDIA RS15270
gene id: 272568:GDIA_RS15270
uniprot id: A9H1K5
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

272568:GDIA RS09540
gene id: 272568:GDIA_RS09540
uniprot id: A9HDN4
names: Function
names: Similarity
messages: A possible function for this protein is to guide the assembly of the membrane sector of the ATPase enzyme complex.
messages: Belongs to the bacterial AtpI family.

272568:GDIA RS14345
gene id: 272568:GDIA_RS14345
uniprot id: B5ZHW3
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

272568:GDIA RS00760
gene id: 272568:GDIA_RS00760
uniprot id: A9HJ69
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

272568:GDIA RS08900
gene id: 272568:GDIA_RS08900
uniprot id: B5ZL08
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

272568:GDIA RS14550
gene id: 272568:GDIA_RS14550
uniprot id: A9H4D4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

272568:GDIA RS01585
gene id: 272568:GDIA_RS01585
uniprot id: A9HKF2
names: Similarity
messages: Belongs to the peptidase U62 family.

272568:GDIA RS03510
gene id: 272568:GDIA_RS03510
uniprot id: A9HN87
names: Similarity
messages: Belongs to the complex I 75 kDa subunit family.

272568:GDIA RS10340
gene id: 272568:GDIA_RS10340
uniprot id: B5ZDI2
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

272568:GDIA RS04745
gene id: 272568:GDIA_RS04745
uniprot id: B5ZFJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TrbI/VirB10 family.
messages: Membrane

272568:GDIA RS00010
gene id: 272568:GDIA_RS00010
uniprot id: B5ZJ25
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

272568:GDIA RS04200
gene id: 272568:GDIA_RS04200
uniprot id: B5ZEZ9
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Catalyzes the phosphorylation of D-xylulose to D-xylulose 5-phosphate.

272568:GDIA RS14970
gene id: 272568:GDIA_RS14970
uniprot id: A9H3K5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

272568:GDIA RS00290
gene id: 272568:GDIA_RS00290
uniprot id: A9HII0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

272568:GDIA RS11740
gene id: 272568:GDIA_RS11740
uniprot id: B5ZF37
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

272568:GDIA RS02535
gene id: 272568:GDIA_RS02535
uniprot id: A9HLY3
names: Function
names: Similarity
names: Subunit
messages: ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.
messages: Belongs to the ParA family. MinD subfamily.
messages: Interacts with MinC and FtsZ.

272568:GDIA RS05255
gene id: 272568:GDIA_RS05255
uniprot id: B5ZG46
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

272568:GDIA RS01935
gene id: 272568:GDIA_RS01935
uniprot id: B5ZLP7
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 5 (UDGb) family.

272568:GDIA RS14310
gene id: 272568:GDIA_RS14310
uniprot id: B5ZHV6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AcsB/BcsB family.
messages: Binds the cellulose synthase activator, bis-(3'-5') cyclic diguanylic acid (c-di-GMP).
messages: Cell inner membrane
messages: Tightly associated with the cellulose synthase catalytic subunit.

272568:GDIA RS01675
gene id: 272568:GDIA_RS01675
uniprot id: B5ZLJ7
names: Similarity
messages: Belongs to the glutamate synthase family.

272568:GDIA RS17515
gene id: 272568:GDIA_RS17515
uniprot id: B5ZCX7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of five rings (E,L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

272568:GDIA RS14980
gene id: 272568:GDIA_RS14980
uniprot id: A9H3J9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.
messages: Cytoplasm
messages: Monomer.

272568:GDIA RS05740
gene id: 272568:GDIA_RS05740
uniprot id: A9HBF6
names: Similarity
messages: Belongs to the aldose epimerase family.

272568:GDIA RS14600
gene id: 272568:GDIA_RS14600
uniprot id: B5ZIA7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

272568:GDIA RS03020
gene id: 272568:GDIA_RS03020
uniprot id: B5ZDS3
names: Similarity
messages: Belongs to the adrenodoxin/putidaredoxin family.

272568:GDIA RS11810
gene id: 272568:GDIA_RS11810
uniprot id: B5ZF51
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

272568:GDIA RS00905
gene id: 272568:GDIA_RS00905
uniprot id: B5ZK36
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG).

272568:GDIA RS01685
gene id: 272568:GDIA_RS01685
uniprot id: A9HKL6
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.

272568:GDIA RS02980
gene id: 272568:GDIA_RS02980
uniprot id: A9HMG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family.
messages: Membrane

272568:GDIA RS15585
gene id: 272568:GDIA_RS15585
uniprot id: A9H118
names: Subcellular Location Annotation
messages: Membrane

272568:GDIA RS11480
gene id: 272568:GDIA_RS11480
uniprot id: B5ZEP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

272568:GDIA RS07695
gene id: 272568:GDIA_RS07695
uniprot id: B5ZJC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

272568:GDIA RS03400
gene id: 272568:GDIA_RS03400
uniprot id: A9HN27
names: Subcellular Location Annotation
messages: Membrane

272568:GDIA RS10280
gene id: 272568:GDIA_RS10280
uniprot id: B5ZDH0
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PdxA family.
messages: Binds 1 divalent metal cation per subunit. Can use ions such as Zn(2+), Mg(2+) or Co(2+).
messages: Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L-threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).
messages: Cytoplasm
messages: Homodimer.
messages: The active site is located at the dimer interface.

272568:GDIA RS02415
gene id: 272568:GDIA_RS02415
uniprot id: B5ZCL0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 2 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

272568:GDIA RS04970
gene id: 272568:GDIA_RS04970
uniprot id: B5ZFY3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

272568:GDIA RS17815
gene id: 272568:GDIA_RS17815
uniprot id: A9HHZ5
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

272568:GDIA RS14195
gene id: 272568:GDIA_RS14195
uniprot id: B5ZHT6
names: Similarity
messages: Belongs to the TrbG/VirB9 family.

272568:GDIA RS14865
gene id: 272568:GDIA_RS14865
uniprot id: A9H3R7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

272568:GDIA RS15915
gene id: 272568:GDIA_RS15915
uniprot id: A9H0I3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

272568:GDIA RS01975
gene id: 272568:GDIA_RS01975
uniprot id: B5ZCC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

272568:GDIA RS10180
gene id: 272568:GDIA_RS10180
uniprot id: A9HEM3
names: Similarity
messages: Belongs to the LOG family.

272568:GDIA RS11380
gene id: 272568:GDIA_RS11380
uniprot id: B5ZEM1
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.

272568:GDIA RS07240
gene id: 272568:GDIA_RS07240
uniprot id: A9H890
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic sulfate-binding protein family.
messages: Periplasm

272568:GDIA RS00795
gene id: 272568:GDIA_RS00795
uniprot id: A9HJ86
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

272568:GDIA RS10610
gene id: 272568:GDIA_RS10610
uniprot id: A9HFD5
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur, cytochrome b-556, and a hydrophobic anchor protein.

272568:GDIA RS10445
gene id: 272568:GDIA_RS10445
uniprot id: A9HF26
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

272568:GDIA RS08770
gene id: 272568:GDIA_RS08770
uniprot id: A9HGC9
names: Function
names: Similarity
messages: Belongs to the transposase 11 family.
messages: Involved in the transposition of the insertion sequence IS5.

272568:GDIA RS08485
gene id: 272568:GDIA_RS08485
uniprot id: B5ZKA1
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

272568:GDIA RS02265
gene id: 272568:GDIA_RS02265
uniprot id: B5ZCI0
names: Subcellular Location Annotation
messages: Membrane

272568:GDIA RS10450
gene id: 272568:GDIA_RS10450
uniprot id: A9HF29
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

272568:GDIA RS11220
gene id: 272568:GDIA_RS11220
uniprot id: B5ZEJ1
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

272568:GDIA RS14985
gene id: 272568:GDIA_RS14985
uniprot id: A9H3J7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

272568:GDIA RS02735
gene id: 272568:GDIA_RS02735
uniprot id: A9HM70
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

272568:GDIA RS11215
gene id: 272568:GDIA_RS11215
uniprot id: A9HGB7
names: Function
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase family.
messages: CoA transferase having broad substrate specificity for short-chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons.

272568:GDIA RS07900
gene id: 272568:GDIA_RS07900
uniprot id: B5ZJG2
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

272568:GDIA RS14860
gene id: 272568:GDIA_RS14860
uniprot id: A9H3R8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

272568:GDIA RS14715
gene id: 272568:GDIA_RS14715
uniprot id: Q69AY8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmE/CycJ family.
messages: Cell inner membrane
messages: Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity). Also required for indole-3-acetic acid (IAA) biosynthesis.

272568:GDIA RS08995
gene id: 272568:GDIA_RS08995
uniprot id: A9H1J2
names: Function
names: Similarity
messages: Belongs to the transposase 11 family.
messages: Involved in the transposition of the insertion sequence IS5.

272568:GDIA RS16340
gene id: 272568:GDIA_RS16340
uniprot id: B5ZKK8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S33 family.
messages: Cytoplasm

272568:GDIA RS15910
gene id: 272568:GDIA_RS15910
uniprot id: A9H0I7
names: Subcellular Location Annotation
messages: Membrane

272568:GDIA RS01780
gene id: 272568:GDIA_RS01780
uniprot id: A9HKQ8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

272568:GDIA RS04770
gene id: 272568:GDIA_RS04770
uniprot id: B5ZFJ8
names: Similarity
messages: Belongs to the TrbE/VirB4 family.

272568:GDIA RS08130
gene id: 272568:GDIA_RS08130
uniprot id: B5ZJK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

272568:GDIA RS00685
gene id: 272568:GDIA_RS00685
uniprot id: B5ZJZ3
names: Similarity
messages: Belongs to the aspartokinase family.

272568:GDIA RS04240
gene id: 272568:GDIA_RS04240
uniprot id: A9HPH6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

272568:GDIA RS14910
gene id: 272568:GDIA_RS14910
uniprot id: A9H3P2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

272568:GDIA RS02275
gene id: 272568:GDIA_RS02275
uniprot id: B5ZCI2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

272568:GDIA RS01760
gene id: 272568:GDIA_RS01760
uniprot id: B5ZLL1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

272568:GDIA RS06070
gene id: 272568:GDIA_RS06070
uniprot id: B5ZH38
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

272568:GDIA RS04700
gene id: 272568:GDIA_RS04700
uniprot id: B5ZFI4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

272568:GDIA RS01530
gene id: 272568:GDIA_RS01530
uniprot id: B5ZLG7
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

272568:GDIA RS01185
gene id: 272568:GDIA_RS01185
uniprot id: B5ZKR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

272568:GDIA RS14830
gene id: 272568:GDIA_RS14830
uniprot id: A9H3T0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

272568:GDIA RS01330
gene id: 272568:GDIA_RS01330
uniprot id: B5ZKU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Cell membrane
messages: Membrane

272568:GDIA RS07100
gene id: 272568:GDIA_RS07100
uniprot id: A9H8E1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

272568:GDIA RS07230
gene id: 272568:GDIA_RS07230
uniprot id: B5ZII5
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cell inner membrane
messages: Membrane
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

272568:GDIA RS02050
gene id: 272568:GDIA_RS02050
uniprot id: P84838
names: Function
names: Induction
names: Subcellular Location Annotation
messages: By cellobiose.
messages: Cell outer membrane
messages: Growth enhancer.

272568:GDIA RS00840
gene id: 272568:GDIA_RS00840
uniprot id: A9HJB2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: Forms a 24-polypeptide structural core with octahedral symmetry.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

272568:GDIA RS12620
gene id: 272568:GDIA_RS12620
uniprot id: B5ZFU6
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

272568:GDIA RS10780
gene id: 272568:GDIA_RS10780
uniprot id: B5ZE12
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

272568:GDIA RS13040
gene id: 272568:GDIA_RS13040
uniprot id: B5ZGD0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

272568:GDIA RS01170
gene id: 272568:GDIA_RS01170
uniprot id: B5ZKR4
names: PTM
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.
messages: Carbamylation allows a single lysine to coordinate two divalent metal cations.

272568:GDIA RS01925
gene id: 272568:GDIA_RS01925
uniprot id: B5ZLP5
names: Function
names: Similarity
messages: Belongs to the HPPK family.
messages: Catalyzes the transfer of pyrophosphate from adenosine triphosphate (ATP) to 6-hydroxymethyl-7,8-dihydropterin, an enzymatic step in folate biosynthesis pathway.

272568:GDIA RS04350
gene id: 272568:GDIA_RS04350
uniprot id: B5ZFC4
names: Function
names: Similarity
messages: In the C-terminal section; belongs to the aldehyde dehydrogenase family.
messages: In the N-terminal section; belongs to the proline dehydrogenase family.
messages: Oxidizes proline to glutamate for use as a carbon and nitrogen source.

272568:GDIA RS15780
gene id: 272568:GDIA_RS15780
uniprot id: B5ZJS4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 87 family.
messages: Membrane

272568:GDIA RS07705
gene id: 272568:GDIA_RS07705
uniprot id: B5ZJC3
names: Similarity
messages: Belongs to the peptidase M20A family. ArgE subfamily.

272568:GDIA RS03435
gene id: 272568:GDIA_RS03435
uniprot id: B5ZE97
names: Cofactor
messages: Can also use Mn(2+) ion.

272568:GDIA RS14295
gene id: 272568:GDIA_RS14295
uniprot id: A9H4S5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

272568:GDIA RS05455
gene id: 272568:GDIA_RS05455
uniprot id: B5ZGH2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

272568:GDIA RS07140
gene id: 272568:GDIA_RS07140
uniprot id: A9H8C0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

272568:GDIA RS16820
gene id: 272568:GDIA_RS16820
uniprot id: A9HRQ9
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

272568:GDIA RS11665
gene id: 272568:GDIA_RS11665
uniprot id: A9H2R8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

272568:GDIA RS11765
gene id: 272568:GDIA_RS11765
uniprot id: A9H2W7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

272568:GDIA RS15265
gene id: 272568:GDIA_RS15265
uniprot id: A9H1K8
names: Subcellular Location Annotation
messages: Membrane

272568:GDIA RS14400
gene id: 272568:GDIA_RS14400
uniprot id: A9H4M0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

272568:GDIA RS01390
gene id: 272568:GDIA_RS01390
uniprot id: A9HK37
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

272568:GDIA RS14840
gene id: 272568:GDIA_RS14840
uniprot id: A9H3S4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

272568:GDIA RS16375
gene id: 272568:GDIA_RS16375
uniprot id: A9HSA0
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

272568:GDIA RS15000
gene id: 272568:GDIA_RS15000
uniprot id: A9H3I6
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

272568:GDIA RS01115
gene id: 272568:GDIA_RS01115
uniprot id: B5ZKQ3
names: Function
names: Similarity
messages: Belongs to the polysaccharide deacetylase family.
messages: Is involved in generating a small heat-stable compound (Nod), an acylated oligomer of N-acetylglucosamine, that stimulates mitosis in various plant protoplasts.

272568:GDIA RS09065
gene id: 272568:GDIA_RS09065
uniprot id: A9HGR3
names: Similarity
messages: Belongs to the UPF0260 family.

272568:GDIA RS15250
gene id: 272568:GDIA_RS15250
uniprot id: A9H1L7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

272568:GDIA RS14055
gene id: 272568:GDIA_RS14055
uniprot id: B5ZHQ8
names: Similarity
messages: Belongs to the virb1 family.

272568:GDIA RS10430
gene id: 272568:GDIA_RS10430
uniprot id: A9HF18
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

272568:GDIA RS07490
gene id: 272568:GDIA_RS07490
uniprot id: A9H6E1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

272568:GDIA RS01900
gene id: 272568:GDIA_RS01900
uniprot id: A9HKX5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

272568:GDIA RS11460
gene id: 272568:GDIA_RS11460
uniprot id: A9H2F5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LamB/PxpA family.
messages: Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
messages: Forms a complex composed of PxpA, PxpB and PxpC.

272568:GDIA RS15870
gene id: 272568:GDIA_RS15870
uniprot id: A9H0K8
names: Function
names: Similarity
messages: Belongs to the LpxC family.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.

272568:GDIA RS14570
gene id: 272568:GDIA_RS14570
uniprot id: B5ZIA1
names: Similarity
messages: Belongs to the ClpA/ClpB family.

272568:GDIA RS01320
gene id: 272568:GDIA_RS01320
uniprot id: A9HJZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron.
messages: Heterooctamer of two A chains, two B chains, two C chains and two D chains.
messages: Membrane

272568:GDIA RS14895
gene id: 272568:GDIA_RS14895
uniprot id: A9H3Q2
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

272568:GDIA RS01200
gene id: 272568:GDIA_RS01200
uniprot id: A9HJU7
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

272568:GDIA RS05880
gene id: 272568:GDIA_RS05880
uniprot id: A9HB75
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

272568:GDIA RS02965
gene id: 272568:GDIA_RS02965
uniprot id: A9HMF6
names: Function
names: Similarity
messages: Belongs to the catalase family. HPII subfamily.
messages: Serves to protect cells from the toxic effects of hydrogen peroxide.

272568:GDIA RS02715
gene id: 272568:GDIA_RS02715
uniprot id: B5ZD99
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

272568:GDIA RS17035
gene id: 272568:GDIA_RS17035
uniprot id: B5ZM13
names: Subcellular Location Annotation
messages: Membrane

272568:GDIA RS17790
gene id: 272568:GDIA_RS17790
uniprot id: A9HHY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

272568:GDIA RS14900
gene id: 272568:GDIA_RS14900
uniprot id: A9H3P8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity).

272568:GDIA RS05280
gene id: 272568:GDIA_RS05280
uniprot id: B5ZG51
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

272568:GDIA RS10150
gene id: 272568:GDIA_RS10150
uniprot id: B5ZCW6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the threonine aldolase family.
messages: Catalyzes the cleavage of L-allo-threonine and L-threonine to glycine and acetaldehyde.
messages: Homotetramer.

272568:GDIA RS06155
gene id: 272568:GDIA_RS06155
uniprot id: A9HAP7
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.
messages: Toroid-shaped homodecamer, composed of two pentamers of five dimers.

272568:GDIA RS09845
gene id: 272568:GDIA_RS09845
uniprot id: A9HE49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

272568:GDIA RS01845
gene id: 272568:GDIA_RS01845
uniprot id: A9HKU2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

272568:GDIA RS11960
gene id: 272568:GDIA_RS11960
uniprot id: B5ZF77
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial microcompartment
messages: Belongs to the EutB family.
messages: Binds between the large and small subunits.
messages: Catalyzes the deamination of various vicinal amino-alcohols to oxo compounds. Allows this organism to utilize ethanolamine as the sole source of nitrogen and carbon in the presence of vitamin B12.
messages: The basic unit is a heterodimer which dimerizes to form tetramers. The heterotetramers trimerize; 6 large subunits form a core ring with 6 small subunits projecting outwards.

272568:GDIA RS02220
gene id: 272568:GDIA_RS02220
uniprot id: B5ZCH1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatB family.
messages: Cell inner membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

272568:GDIA RS07820
gene id: 272568:GDIA_RS07820
uniprot id: B5ZJE6
names: Function
names: Similarity
messages: Belongs to the NifD/NifK/NifE/NifN family.
messages: This protein may play a role in the biosynthesis of the prosthetic group of nitrogenase (FeMo cofactor).

272568:GDIA RS00425
gene id: 272568:GDIA_RS00425
uniprot id: A9HIQ1
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

272568:GDIA RS14875
gene id: 272568:GDIA_RS14875
uniprot id: A9H3R5
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: Methylated by PrmB.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

272568:GDIA RS10925
gene id: 272568:GDIA_RS10925
uniprot id: B5ZE41
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.

272568:GDIA RS15130
gene id: 272568:GDIA_RS15130
uniprot id: A9H3B5
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

272568:GDIA RS07755
gene id: 272568:GDIA_RS07755
uniprot id: B5ZJD3
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

272568:GDIA RS01870
gene id: 272568:GDIA_RS01870
uniprot id: A9HKV5
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

272568:GDIA RS06025
gene id: 272568:GDIA_RS06025
uniprot id: A9HAZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

272568:GDIA RS05680
gene id: 272568:GDIA_RS05680
uniprot id: B5ZGL6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueG family.
messages: Binds 2 [4Fe-4S] clusters per monomer.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

272568:GDIA RS15600
gene id: 272568:GDIA_RS15600
uniprot id: B5ZJP1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

272568:GDIA RS14710
gene id: 272568:GDIA_RS14710
uniprot id: A9H409
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.
messages: Cell inner membrane
messages: Membrane

272568:GDIA RS06540
gene id: 272568:GDIA_RS06540
uniprot id: A9H9A8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

272568:GDIA RS14465
gene id: 272568:GDIA_RS14465
uniprot id: B5ZHY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
messages: Cell inner membrane

272568:GDIA RS16660
gene id: 272568:GDIA_RS16660
uniprot id: A9HRW8
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

272568:GDIA RS09150
gene id: 272568:GDIA_RS09150
uniprot id: B5ZL57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

272568:GDIA RS12735
gene id: 272568:GDIA_RS12735
uniprot id: B5ZG68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OprB family.
messages: Cell outer membrane

272568:GDIA RS09655
gene id: 272568:GDIA_RS09655
uniprot id: B5ZCL9
names: Similarity
messages: Belongs to the YggT family.

272568:GDIA RS17410
gene id: 272568:GDIA_RS17410
uniprot id: A9HHB6
names: Function
names: Similarity
messages: Belongs to the FlgD family.
messages: Required for flagellar hook formation. May act as a scaffolding protein.

272568:GDIA RS01210
gene id: 272568:GDIA_RS01210
uniprot id: B5ZKS2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

272568:GDIA RS13445
gene id: 272568:GDIA_RS13445
uniprot id: A9H9Q9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DksA family.
messages: Cytoplasm
messages: Interacts directly with the RNA polymerase.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters.

272568:GDIA RS07420
gene id: 272568:GDIA_RS07420
uniprot id: A9H7Y4
names: Similarity
messages: Belongs to the alkylbase DNA glycosidase AlkA family.

272568:GDIA RS08005
gene id: 272568:GDIA_RS08005
uniprot id: B5ZJI1
names: Similarity
messages: Belongs to the virb1 family.

272568:GDIA RS01625
gene id: 272568:GDIA_RS01625
uniprot id: A9HKH7
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell inner membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.

272568:GDIA RS13470
gene id: 272568:GDIA_RS13470
uniprot id: A9HPY4
names: Similarity
messages: Belongs to the transposase IS21/IS408/IS1162 family.

272568:GDIA RS07300
gene id: 272568:GDIA_RS07300
uniprot id: A9H852
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 13 family.
messages: Cytoplasm

272568:GDIA RS11520
gene id: 272568:GDIA_RS11520
uniprot id: A9H2J4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

272568:GDIA RS02530
gene id: 272568:GDIA_RS02530
uniprot id: B5ZD63
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MinC family.
messages: Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization.
messages: Interacts with MinD and FtsZ.

272568:GDIA RS03130
gene id: 272568:GDIA_RS03130
uniprot id: B5ZDU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

272568:GDIA RS14085
gene id: 272568:GDIA_RS14085
uniprot id: B5ZHR4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

272568:GDIA RS07270
gene id: 272568:GDIA_RS07270
uniprot id: A9H869
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

272568:GDIA RS15180
gene id: 272568:GDIA_RS15180
uniprot id: A9H385
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

272568:GDIA RS15930
gene id: 272568:GDIA_RS15930
uniprot id: A9H0H5
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

272568:GDIA RS04990
gene id: 272568:GDIA_RS04990
uniprot id: B5ZFY8
names: Similarity
messages: Belongs to the TrbL/VirB6 family.

272568:GDIA RS16040
gene id: 272568:GDIA_RS16040
uniprot id: A9H0C5
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

272568:GDIA RS10300
gene id: 272568:GDIA_RS10300
uniprot id: B5ZDH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

272568:GDIA RS10455
gene id: 272568:GDIA_RS10455
uniprot id: A9HF35
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

272568:GDIA RS08540
gene id: 272568:GDIA_RS08540
uniprot id: B5ZKB2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

272568:GDIA RS16775
gene id: 272568:GDIA_RS16775
uniprot id: A9HRS6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell inner membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

272568:GDIA RS13655
gene id: 272568:GDIA_RS13655
uniprot id: B5ZH84
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

272568:GDIA RS14605
gene id: 272568:GDIA_RS14605
uniprot id: A9H481
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

272568:GDIA RS11790
gene id: 272568:GDIA_RS11790
uniprot id: B5ZF47
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the aromatic amine dehydrogenase light chain family.
messages: Heterotetramer of two light and two heavy chains.
messages: Methylamine dehydrogenase carries out the oxidation of methylamine. Electrons are passed from methylamine dehydrogenase to amicyanin.
messages: Periplasm

272568:GDIA RS11135
gene id: 272568:GDIA_RS11135
uniprot id: A9HG69
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

272568:GDIA RS01505
gene id: 272568:GDIA_RS01505
uniprot id: A9HKA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

272568:GDIA RS09355
gene id: 272568:GDIA_RS09355
uniprot id: B5ZLU0
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

272568:GDIA RS07915
gene id: 272568:GDIA_RS07915
uniprot id: B5ZJG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

272568:GDIA RS14505
gene id: 272568:GDIA_RS14505
uniprot id: B5ZI89
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

272568:GDIA RS07935
gene id: 272568:GDIA_RS07935
uniprot id: A9H5P1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the encapsulin family. Family 1 subfamily.
messages: Encapsulin nanocompartment

272568:GDIA RS04980
gene id: 272568:GDIA_RS04980
uniprot id: B5ZFY6
names: Similarity
messages: Belongs to the TrbG/VirB9 family.

272568:GDIA RS05650
gene id: 272568:GDIA_RS05650
uniprot id: A9HBK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1C family.
messages: Periplasm

272568:GDIA RS08180
gene id: 272568:GDIA_RS08180
uniprot id: A9GZU5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated exonuclease Cas4 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).
messages: Mg(2+) or Mn(2+) required for ssDNA cleavage activity.

272568:GDIA RS16240
gene id: 272568:GDIA_RS16240
uniprot id: B5ZKJ0
names: Similarity
messages: Belongs to the ArsC family.

272568:GDIA RS10385
gene id: 272568:GDIA_RS10385
uniprot id: A9HEZ5
names: Similarity
messages: Belongs to the ABC transporter superfamily.

272568:GDIA RS10580
gene id: 272568:GDIA_RS10580
uniprot id: A9HFC1
names: Similarity
messages: Belongs to the ros/MucR family.

272568:GDIA RS16000
gene id: 272568:GDIA_RS16000
uniprot id: A9H0E5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

272568:GDIA RS03525
gene id: 272568:GDIA_RS03525
uniprot id: A9HN95
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cell inner membrane
messages: In the C-terminal section; belongs to the complex I 49 kDa subunit family.
messages: In the N-terminal section; belongs to the complex I 30 kDa subunit family.
messages: NDH-1 is composed of 13 different subunits. Subunits NuoB, CD, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

272568:GDIA RS09830
gene id: 272568:GDIA_RS09830
uniprot id: A9HE41
names: Cofactor
messages: Binds 1 Fe(2+) ion per subunit.

272568:GDIA RS07350
gene id: 272568:GDIA_RS07350
uniprot id: B5ZIK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell inner membrane
messages: Membrane

272568:GDIA RS15690
gene id: 272568:GDIA_RS15690
uniprot id: B5ZJQ9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

272568:GDIA RS09520
gene id: 272568:GDIA_RS09520
uniprot id: A9HDM4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell inner membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.

272568:GDIA RS08715
gene id: 272568:GDIA_RS08715
uniprot id: B5ZKY1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

272568:GDIA RS04355
gene id: 272568:GDIA_RS04355
uniprot id: A9HPP2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

272568:GDIA RS14890
gene id: 272568:GDIA_RS14890
uniprot id: A9H3Q5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

272568:GDIA RS16615
gene id: 272568:GDIA_RS16615
uniprot id: B5ZL94
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

272568:GDIA RS06745
gene id: 272568:GDIA_RS06745
uniprot id: B5ZHZ5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobD/CbiB family.
messages: Cell membrane
messages: Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

272568:GDIA RS05085
gene id: 272568:GDIA_RS05085
uniprot id: B5ZG09
names: Similarity
messages: Belongs to the virb1 family.

272568:GDIA RS14880
gene id: 272568:GDIA_RS14880
uniprot id: A9H3R2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

272568:GDIA RS06770
gene id: 272568:GDIA_RS06770
uniprot id: B5ZI00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oxidase-dependent Fe transporter (OFeT) (TC 9.A.10.1) family.
messages: Membrane

272568:GDIA RS08955
gene id: 272568:GDIA_RS08955
uniprot id: A9GZH4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

272568:GDIA RS02725
gene id: 272568:GDIA_RS02725
uniprot id: A9HM65
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

272568:GDIA RS08600
gene id: 272568:GDIA_RS08600
uniprot id: B5ZKC4
names: Subcellular Location Annotation
messages: Membrane

272568:GDIA RS03430
gene id: 272568:GDIA_RS03430
uniprot id: B5ZE96
names: Similarity
messages: Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family.

272568:GDIA RS04145
gene id: 272568:GDIA_RS04145
uniprot id: A9HPC0
names: Subcellular Location Annotation
messages: Membrane

272568:GDIA RS17030
gene id: 272568:GDIA_RS17030
uniprot id: A9HRG7
names: Function
names: Subunit
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease.

272568:GDIA RS16430
gene id: 272568:GDIA_RS16430
uniprot id: A9HS74
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

272568:GDIA RS08840
gene id: 272568:GDIA_RS08840
uniprot id: B5ZEJ1
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

272568:GDIA RS02430
gene id: 272568:GDIA_RS02430
uniprot id: B5ZCL3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

272568:GDIA RS02390
gene id: 272568:GDIA_RS02390
uniprot id: B5ZCK6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoH subfamily.
messages: Cytoplasm
messages: Interacts with the RNA polymerase core enzyme.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes.

272568:GDIA RS12685
gene id: 272568:GDIA_RS12685
uniprot id: B5ZG57
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

272568:GDIA RS01905
gene id: 272568:GDIA_RS01905
uniprot id: B5ZLP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

272568:GDIA RS08105
gene id: 272568:GDIA_RS08105
uniprot id: B5ZJJ5
names: Similarity
messages: Belongs to the UbiH/COQ6 family.

272568:GDIA RS10035
gene id: 272568:GDIA_RS10035
uniprot id: A9HEE9
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

272568:GDIA RS15195
gene id: 272568:GDIA_RS15195
uniprot id: A9H1Q0
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

272568:GDIA RS17685
gene id: 272568:GDIA_RS17685
uniprot id: A9HHS4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell inner membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

272568:GDIA RS17325
gene id: 272568:GDIA_RS17325
uniprot id: A9HH69
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

272568:GDIA RS16960
gene id: 272568:GDIA_RS16960
uniprot id: B5ZLF6
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

272568:GDIA RS05790
gene id: 272568:GDIA_RS05790
uniprot id: B5ZGX9
names: Cofactor
messages: Binds 3 heme c groups covalently per subunit.

272568:GDIA RS06475
gene id: 272568:GDIA_RS06475
uniprot id: B5ZHK2
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

272568:GDIA RS14090
gene id: 272568:GDIA_RS14090
uniprot id: B5ZHR5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

272568:GDIA RS04070
gene id: 272568:GDIA_RS04070
uniprot id: B5ZEX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Membrane

272568:GDIA RS03980
gene id: 272568:GDIA_RS03980
uniprot id: B5ZEV5
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

272568:GDIA RS14660
gene id: 272568:GDIA_RS14660
uniprot id: B5ZIB9
names: Similarity
messages: Belongs to the shaker potassium channel beta subunit family.

272568:GDIA RS16580
gene id: 272568:GDIA_RS16580
uniprot id: A9HS05
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

272568:GDIA RS01950
gene id: 272568:GDIA_RS01950
uniprot id: B5ZLQ0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MsrQ family.
messages: Binds 1 FMN per subunit.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Cell inner membrane
messages: Heterodimer of a catalytic subunit (MsrP) and a heme-binding subunit (MsrQ).
messages: Membrane
messages: Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain.

272568:GDIA RS16290
gene id: 272568:GDIA_RS16290
uniprot id: B5ZEJ1
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

272568:GDIA RS11190
gene id: 272568:GDIA_RS11190
uniprot id: A9HGA4
names: Subcellular Location Annotation
messages: Membrane

272568:GDIA RS11285
gene id: 272568:GDIA_RS11285
uniprot id: B5ZEK3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic Ku family.
messages: Homodimer. Interacts with LigD.
messages: With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD.

272568:GDIA RS05405
gene id: 272568:GDIA_RS05405
uniprot id: A9HC01
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

272568:GDIA RS16475
gene id: 272568:GDIA_RS16475
uniprot id: A9HS52
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

272568:GDIA RS16390
gene id: 272568:GDIA_RS16390
uniprot id: B5ZKL8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

272568:GDIA RS14935
gene id: 272568:GDIA_RS14935
uniprot id: A9H3M8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

272568:GDIA RS16460
gene id: 272568:GDIA_RS16460
uniprot id: A9HS58
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

272568:GDIA RS15720
gene id: 272568:GDIA_RS15720
uniprot id: A9H0S9
names: Similarity
messages: Belongs to the DEAD box helicase family.

272568:GDIA RS10240
gene id: 272568:GDIA_RS10240
uniprot id: B5ZDG2
names: Cofactor
names: Function
names: Similarity
messages: Adenine glycosylase active on G-A mispairs. MutY also corrects error-prone DNA synthesis past GO lesions which are due to the oxidatively damaged form of guanine: 7,8-dihydro-8-oxoguanine (8-oxo-dGTP).
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.

272568:GDIA RS07565
gene id: 272568:GDIA_RS07565
uniprot id: B5ZIQ3
names: Similarity
messages: Belongs to the class I fructose-bisphosphate aldolase family.

272568:GDIA RS09630
gene id: 272568:GDIA_RS09630
uniprot id: B5ZLZ5
names: Subcellular Location Annotation
messages: Membrane

272568:GDIA RS16455
gene id: 272568:GDIA_RS16455
uniprot id: A9HS61
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

272568:GDIA RS00910
gene id: 272568:GDIA_RS00910
uniprot id: B5ZK37
names: Similarity
messages: Belongs to the transglycosylase Slt family.
messages: Belongs to the virb1 family.

272568:GDIA RS03000
gene id: 272568:GDIA_RS03000
uniprot id: B5ZDR9
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

272568:GDIA RS07265
gene id: 272568:GDIA_RS07265
uniprot id: A9H872
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

272568:GDIA RS10380
gene id: 272568:GDIA_RS10380
uniprot id: B5ZDJ0
names: Function
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.

272568:GDIA RS10015
gene id: 272568:GDIA_RS10015
uniprot id: A9HED8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Involved in the heme biosynthesis. Catalyzes the anaerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen III to yield the vinyl groups in protoporphyrinogen IX.
messages: Monomer.

272568:GDIA RS09690
gene id: 272568:GDIA_RS09690
uniprot id: A9HDW7
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

272568:GDIA RS12625
gene id: 272568:GDIA_RS12625
uniprot id: A9HCQ6
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

272568:GDIA RS02865
gene id: 272568:GDIA_RS02865
uniprot id: B5ZDE2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

272568:GDIA RS09940
gene id: 272568:GDIA_RS09940
uniprot id: A9HE99
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

272568:GDIA RS16440
gene id: 272568:GDIA_RS16440
uniprot id: A9HS68
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Cell inner membrane
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

272568:GDIA RS07605
gene id: 272568:GDIA_RS07605
uniprot id: A9H684
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

272568:GDIA RS03565
gene id: 272568:GDIA_RS03565
uniprot id: A9HNB4
names: Similarity
messages: Belongs to the bacterial phospholipase C family.

272568:GDIA RS07060
gene id: 272568:GDIA_RS07060
uniprot id: A9H8G4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acireductone dioxygenase (ARD) family.
messages: Binds 1 Fe(2+) cation per monomer.
messages: Binds 1 nickel ion per monomer.
messages: Catalyzes 2 different reactions between oxygen and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
messages: Monomer.

272568:GDIA RS10920
gene id: 272568:GDIA_RS10920
uniprot id: B5ZE40
names: Similarity
messages: Belongs to the band 7/mec-2 family.

272568:GDIA RS15640
gene id: 272568:GDIA_RS15640
uniprot id: A9H0Y0
names: Function
names: Similarity
messages: Belongs to the LpxK family.
messages: Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).

272568:GDIA RS07170
gene id: 272568:GDIA_RS07170
uniprot id: B5ZI77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

272568:GDIA RS08560
gene id: 272568:GDIA_RS08560
uniprot id: B5ZKB6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

272568:GDIA RS08245
gene id: 272568:GDIA_RS08245
uniprot id: B5ZK59
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

272568:GDIA RS05560
gene id: 272568:GDIA_RS05560
uniprot id: B5ZGJ2
names: Cofactor
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

272568:GDIA RS06420
gene id: 272568:GDIA_RS06420
uniprot id: B5ZHJ1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

272568:GDIA RS06080
gene id: 272568:GDIA_RS06080
uniprot id: B5ZH40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

272568:GDIA RS11355
gene id: 272568:GDIA_RS11355
uniprot id: A9H298
names: Similarity
messages: Belongs to the UPF0434 family.

272568:GDIA RS13970
gene id: 272568:GDIA_RS13970
uniprot id: B5ZHE7
names: Similarity
messages: Belongs to the SBNO family.

272568:GDIA RS17320
gene id: 272568:GDIA_RS17320
uniprot id: B5ZM64
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

272568:GDIA RS06525
gene id: 272568:GDIA_RS06525
uniprot id: A9H9B7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase D family.
messages: Cytoplasm
messages: Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides.

272568:GDIA RS11195
gene id: 272568:GDIA_RS11195
uniprot id: B5ZEI7
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

272568:GDIA RS15360
gene id: 272568:GDIA_RS15360
uniprot id: B5ZJ04
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Monomer.
messages: Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.

272568:GDIA RS06445
gene id: 272568:GDIA_RS06445
uniprot id: A9HA92
names: Similarity
messages: Belongs to the thioredoxin family.

272568:GDIA RS14920
gene id: 272568:GDIA_RS14920
uniprot id: B5ZIH2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

272568:GDIA RS17145
gene id: 272568:GDIA_RS17145
uniprot id: B5ZM35
names: Function
names: Similarity
messages: Belongs to the transglycosylase MltG family.
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

272568:GDIA RS01340
gene id: 272568:GDIA_RS01340
uniprot id: A9HK09
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

272568:GDIA RS00405
gene id: 272568:GDIA_RS00405
uniprot id: A9HIP1
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.

272568:GDIA RS01820
gene id: 272568:GDIA_RS01820
uniprot id: B5ZLM4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

272568:GDIA RS14700
gene id: 272568:GDIA_RS14700
uniprot id: B5ZIC8
names: Function
names: Similarity
messages: Belongs to the CcmH/CycL/Ccl2/NrfF family.
messages: Possible subunit of a heme lyase.

272568:GDIA RS08300
gene id: 272568:GDIA_RS08300
uniprot id: A9GZM4
names: Function
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.

272568:GDIA RS01100
gene id: 272568:GDIA_RS01100
uniprot id: B5ZKQ0
names: Similarity
messages: Belongs to the peptidase M24B family.

272568:GDIA RS00285
gene id: 272568:GDIA_RS00285
uniprot id: B5ZJ79
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

272568:GDIA RS00300
gene id: 272568:GDIA_RS00300
uniprot id: B5ZJ82
names: Similarity
messages: Belongs to the citrate synthase family.

272568:GDIA RS07370
gene id: 272568:GDIA_RS07370
uniprot id: A9H809
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

272568:GDIA RS01190
gene id: 272568:GDIA_RS01190
uniprot id: B5ZKR8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Cdh family.
messages: Membrane

272568:GDIA RS06875
gene id: 272568:GDIA_RS06875
uniprot id: A9H8S7
names: Similarity
messages: Belongs to the myo-inositol 1-phosphate synthase family.

272568:GDIA RS15495
gene id: 272568:GDIA_RS15495
uniprot id: B5ZJL9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

272568:GDIA RS01425
gene id: 272568:GDIA_RS01425
uniprot id: A9HK62
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b family.
messages: Binds 2 heme groups non-covalently.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
messages: Membrane
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

272568:GDIA RS03030
gene id: 272568:GDIA_RS03030
uniprot id: B5ZDS5
names: Function
messages: Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Seems to participate in the biosynthesis of the nitrogenase metalloclusters by providing the inorganic sulfur required for the Fe-S core formation.

272568:GDIA RS13375
gene id: 272568:GDIA_RS13375
uniprot id: A9H1J2
names: Function
names: Similarity
messages: Belongs to the transposase 11 family.
messages: Involved in the transposition of the insertion sequence IS5.

272568:GDIA RS17545
gene id: 272568:GDIA_RS17545
uniprot id: B5ZCY3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell inner membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

272568:GDIA RS00785
gene id: 272568:GDIA_RS00785
uniprot id: A9HJ81
names: Activity Regulation
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.

272568:GDIA RS04520
gene id: 272568:GDIA_RS04520
uniprot id: B5ZFF4
names: Similarity
messages: Belongs to the ABC transporter superfamily.

272568:GDIA RS00845
gene id: 272568:GDIA_RS00845
uniprot id: A9HJB6
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

272568:GDIA RS02245
gene id: 272568:GDIA_RS02245
uniprot id: B5ZCH6
names: Similarity
messages: Belongs to the dGTPase family. Type 2 subfamily.

272568:GDIA RS09580
gene id: 272568:GDIA_RS09580
uniprot id: A9HDQ7
names: Function
names: Similarity
messages: Belongs to the RapZ-like family.
messages: Displays ATPase and GTPase activities.

272568:GDIA RS04920
gene id: 272568:GDIA_RS04920
uniprot id: B5ZFX3
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.

272568:GDIA RS10620
gene id: 272568:GDIA_RS10620
uniprot id: A9HFD9
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD.

272568:GDIA RS08255
gene id: 272568:GDIA_RS08255
uniprot id: B5ZK61
names: Similarity
messages: Belongs to the peptidase S41A family.

272568:GDIA RS06185
gene id: 272568:GDIA_RS06185
uniprot id: B5ZH61
names: Similarity
messages: Belongs to the peptidase C56 family.

272568:GDIA RS10585
gene id: 272568:GDIA_RS10585
uniprot id: A9HFC2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a global negative controlling element, employing Fe(2+) as a cofactor to bind the operator of the repressed genes.
messages: Belongs to the Fur family.
messages: Cytoplasm
messages: Homodimer.

272568:GDIA RS07040
gene id: 272568:GDIA_RS07040
uniprot id: B5ZI52
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell inner membrane
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

272568:GDIA RS17395
gene id: 272568:GDIA_RS17395
uniprot id: A9HHA7
names: Similarity
messages: Belongs to the MotB family.

272568:GDIA RS11625
gene id: 272568:GDIA_RS11625
uniprot id: A9H2P2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

272568:GDIA RS11885
gene id: 272568:GDIA_RS11885
uniprot id: A9H341
names: Similarity
messages: Belongs to the gluconokinase GntK/GntV family.

272568:GDIA RS04465
gene id: 272568:GDIA_RS04465
uniprot id: A9HPV0
names: Subcellular Location Annotation
messages: Membrane

272568:GDIA RS14390
gene id: 272568:GDIA_RS14390
uniprot id: B5ZHX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OprB family.
messages: Cell outer membrane

272568:GDIA RS01525
gene id: 272568:GDIA_RS01525
uniprot id: B5ZLG6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell inner membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Membrane

272568:GDIA RS02105
gene id: 272568:GDIA_RS02105
uniprot id: A9HL98
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

272568:GDIA RS17480
gene id: 272568:GDIA_RS17480
uniprot id: B5ZCX0
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

272568:GDIA RS02120
gene id: 272568:GDIA_RS02120
uniprot id: B5ZCF1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

272568:GDIA RS05500
gene id: 272568:GDIA_RS05500
uniprot id: B5ZGI0
names: Subcellular Location Annotation
messages: Membrane

272568:GDIA RS15605
gene id: 272568:GDIA_RS15605
uniprot id: B5ZJP2
names: Function
names: Similarity
messages: Belongs to the glutamate--cysteine ligase type 2 family. EgtA subfamily.
messages: Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC).

272568:GDIA RS06280
gene id: 272568:GDIA_RS06280
uniprot id: B5ZHG4
names: Similarity
messages: Belongs to the DNA photolyase family.

272568:GDIA RS04985
gene id: 272568:GDIA_RS04985
uniprot id: B5ZFY7
names: Subcellular Location Annotation
messages: Membrane

272568:GDIA RS13520
gene id: 272568:GDIA_RS13520
uniprot id: A9H9X2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PstS family.
messages: Part of the ABC transporter complex PstSACB involved in phosphate import.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

272568:GDIA RS14575
gene id: 272568:GDIA_RS14575
uniprot id: B5ZIA2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ClpS family.
messages: Binds to the N-terminal domain of the chaperone ClpA.
messages: Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.

272568:GDIA RS16270
gene id: 272568:GDIA_RS16270
uniprot id: B5ZKJ6
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

272568:GDIA RS05380
gene id: 272568:GDIA_RS05380
uniprot id: A9HC17
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein L14 (rplN).

272568:GDIA RS16415
gene id: 272568:GDIA_RS16415
uniprot id: B5ZKM3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

272568:GDIA RS14655
gene id: 272568:GDIA_RS14655
uniprot id: B5ZIB8
names: Subcellular Location Annotation
messages: Membrane

272568:GDIA RS11065
gene id: 272568:GDIA_RS11065
uniprot id: B5ZE69
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

272568:GDIA RS14845
gene id: 272568:GDIA_RS14845
uniprot id: B5ZIF7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

272568:GDIA RS15460
gene id: 272568:GDIA_RS15460
uniprot id: B5ZJ24
names: Similarity
messages: Belongs to the SufE family.

272568:GDIA RS06895
gene id: 272568:GDIA_RS06895
uniprot id: B5ZI25
names: Similarity
messages: Belongs to the CdaR family.

272568:GDIA RS07865
gene id: 272568:GDIA_RS07865
uniprot id: A9H5T3
names: Function
names: Similarity
messages: Belongs to the radical SAM superfamily. NifB family.
messages: Involved in the biosynthesis of the iron-molybdenum cofactor (FeMo-co or M-cluster) found in the dinitrogenase enzyme of the nitrogenase complex in nitrogen-fixing microorganisms. NifB catalyzes the crucial step of radical SAM-dependent carbide insertion that occurs concomitant with the insertion of a 9th sulfur and the rearrangement/coupling of two [4Fe-4S] clusters into a [8Fe-9S-C] cluster, the precursor to the M-cluster.

272568:GDIA RS16050
gene id: 272568:GDIA_RS16050
uniprot id: A9H0B8
names: Similarity
messages: Belongs to the peptidase S49 family.

272568:GDIA RS04925
gene id: 272568:GDIA_RS04925
uniprot id: B5ZFX4
names: Function
names: Similarity
messages: Belongs to the RecD family. RecD-like subfamily.
messages: DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity.

272568:GDIA RS15300
gene id: 272568:GDIA_RS15300
uniprot id: A9H1J2
names: Function
names: Similarity
messages: Belongs to the transposase 11 family.
messages: Involved in the transposition of the insertion sequence IS5.

272568:GDIA RS13180
gene id: 272568:GDIA_RS13180
uniprot id: B5ZGP6
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

272568:GDIA RS10955
gene id: 272568:GDIA_RS10955
uniprot id: B5ZE47
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family. ParE type 1 subfamily.
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

272568:GDIA RS00610
gene id: 272568:GDIA_RS00610
uniprot id: A9HJ07
names: Similarity
messages: Belongs to the BolA/IbaG family.

272568:GDIA RS16600
gene id: 272568:GDIA_RS16600
uniprot id: B5ZL91
names: Function
messages: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.

272568:GDIA RS15975
gene id: 272568:GDIA_RS15975
uniprot id: A9H0F8
names: Similarity
messages: Belongs to the UPF0335 family.

272568:GDIA RS13420
gene id: 272568:GDIA_RS13420
uniprot id: B5ZGU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

272568:GDIA RS06505
gene id: 272568:GDIA_RS06505
uniprot id: A9H9C1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

272568:GDIA RS10935
gene id: 272568:GDIA_RS10935
uniprot id: B5ZE43
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

272568:GDIA RS08285
gene id: 272568:GDIA_RS08285
uniprot id: A9GZN3
names: Subcellular Location Annotation
messages: Membrane

272568:GDIA RS00830
gene id: 272568:GDIA_RS00830
uniprot id: B5ZK22
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

272568:GDIA RS00890
gene id: 272568:GDIA_RS00890
uniprot id: B5ZK33
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

272568:GDIA RS09165
gene id: 272568:GDIA_RS09165
uniprot id: B5ZL60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OprB family.
messages: Cell outer membrane

272568:GDIA RS16230
gene id: 272568:GDIA_RS16230
uniprot id: B5ZKI8
names: Similarity
messages: Belongs to the phosphohexose mutase family.

272568:GDIA RS03380
gene id: 272568:GDIA_RS03380
uniprot id: A9HN17
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

272568:GDIA RS08235
gene id: 272568:GDIA_RS08235
uniprot id: B5ZK57
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell inner membrane
messages: Probably interacts with PlsX.

272568:GDIA RS00160
gene id: 272568:GDIA_RS00160
uniprot id: A9HIA6
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.

272568:GDIA RS16625
gene id: 272568:GDIA_RS16625
uniprot id: B5ZL96
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

272568:GDIA RS03095
gene id: 272568:GDIA_RS03095
uniprot id: B5ZDT8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

272568:GDIA RS09410
gene id: 272568:GDIA_RS09410
uniprot id: B5ZLV1
names: Similarity
messages: Belongs to the EcnA/EcnB lipoprotein family.