2714036:G6534 RS04535
gene id: 2714036:G6534_RS04535
uniprot id: A0A7L7KVU3
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.

2714036:G6534 RS06495
gene id: 2714036:G6534_RS06495
uniprot id: A0A7L7KYA0
names: Similarity
messages: Belongs to the SAICAR synthetase family.

2714036:G6534 RS07265
gene id: 2714036:G6534_RS07265
uniprot id: A0A7L7L042
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2714036:G6534 RS04215
gene id: 2714036:G6534_RS04215
uniprot id: A0A7L7KVN0
names: Subcellular Location Annotation
messages: Membrane

2714036:G6534 RS07905
gene id: 2714036:G6534_RS07905
uniprot id: A0A7L7KXL6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

2714036:G6534 RS05335
gene id: 2714036:G6534_RS05335
uniprot id: A0A7L7KZ77
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

2714036:G6534 RS08565
gene id: 2714036:G6534_RS08565
uniprot id: A0A7L7KYW8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DEAD box helicase family. CshA subfamily.
messages: Cytoplasm
messages: DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA-dependent ATPase activity.
messages: Oligomerizes, may be a member of the RNA degradosome.

2714036:G6534 RS07780
gene id: 2714036:G6534_RS07780
uniprot id: A0A7L7KXK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acyl-ACP thioesterase family.
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: chloroplast

2714036:G6534 RS08370
gene id: 2714036:G6534_RS08370
uniprot id: A0A7L7KXV4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

2714036:G6534 RS06505
gene id: 2714036:G6534_RS06505
uniprot id: A0A7L7KZQ7
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

2714036:G6534 RS03855
gene id: 2714036:G6534_RS03855
uniprot id: A0A7L7KVU7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

2714036:G6534 RS04730
gene id: 2714036:G6534_RS04730
uniprot id: A0A7L7KYX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0073 (Hly-III) family.
messages: Membrane

2714036:G6534 RS08390
gene id: 2714036:G6534_RS08390
uniprot id: A0A7L7KXY4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

2714036:G6534 RS09325
gene id: 2714036:G6534_RS09325
uniprot id: A0A7L7KYF3
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

2714036:G6534 RS01590
gene id: 2714036:G6534_RS01590
uniprot id: A0A7L7KUD3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

2714036:G6534 RS08430
gene id: 2714036:G6534_RS08430
uniprot id: A0A7L7L0I5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

2714036:G6534 RS03460
gene id: 2714036:G6534_RS03460
uniprot id: A0A7L7KXL4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

2714036:G6534 RS03830
gene id: 2714036:G6534_RS03830
uniprot id: A0A7L7KVG6
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

2714036:G6534 RS02195
gene id: 2714036:G6534_RS02195
uniprot id: A0A7L7KUN4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Could methylate the ribose at the nucleotide 34 wobble position in tRNA.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2714036:G6534 RS04330
gene id: 2714036:G6534_RS04330
uniprot id: A0A7L7KW33
names: Cofactor
messages: Binds 1 Mg(2+) ion per trimer.

2714036:G6534 RS06750
gene id: 2714036:G6534_RS06750
uniprot id: A0A7L7KX71
names: Similarity
messages: Belongs to the asp23 family.

2714036:G6534 RS04055
gene id: 2714036:G6534_RS04055
uniprot id: A0A7L7KVJ3
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

2714036:G6534 RS08350
gene id: 2714036:G6534_RS08350
uniprot id: A0A7L7KXX9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

2714036:G6534 RS08255
gene id: 2714036:G6534_RS08255
uniprot id: A0A7L7KXY2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the energy-coupling factor EcfT family.
messages: Cell membrane
messages: Forms a stable energy-coupling factor (ECF) transporter complex composed of 2 membrane-embedded substrate-binding proteins (S component), 2 ATP-binding proteins (A component) and 2 transmembrane proteins (T component).
messages: Membrane
messages: Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.

2714036:G6534 RS04750
gene id: 2714036:G6534_RS04750
uniprot id: A0A7L7KX96
names: Similarity
messages: Belongs to the UPF0346 family.

2714036:G6534 RS05760
gene id: 2714036:G6534_RS05760
uniprot id: A0A7L7KXH1
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane.

2714036:G6534 RS04890
gene id: 2714036:G6534_RS04890
uniprot id: A0A7L7KX10
names: Subcellular Location Annotation
messages: Membrane

2714036:G6534 RS08380
gene id: 2714036:G6534_RS08380
uniprot id: A0A7L7L1N5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

2714036:G6534 RS01350
gene id: 2714036:G6534_RS01350
uniprot id: A0A7L7KUC4
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

2714036:G6534 RS03245
gene id: 2714036:G6534_RS03245
uniprot id: A0A7L7KWJ2
names: Subcellular Location Annotation
messages: Membrane

2714036:G6534 RS06430
gene id: 2714036:G6534_RS06430
uniprot id: A0A7L7KZ38
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

2714036:G6534 RS06240
gene id: 2714036:G6534_RS06240
uniprot id: A0A7L7KWS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Cytoplasm

2714036:G6534 RS08790
gene id: 2714036:G6534_RS08790
uniprot id: A0A7L7KY59
names: Similarity
messages: Belongs to the DtxR/MntR family.

2714036:G6534 RS03720
gene id: 2714036:G6534_RS03720
uniprot id: A0A7L7KWB3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

2714036:G6534 RS06465
gene id: 2714036:G6534_RS06465
uniprot id: A0A7L7KWX2
names: Caution
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2714036:G6534 RS09050
gene id: 2714036:G6534_RS09050
uniprot id: A0A7L7L0P3
names: Subcellular Location Annotation
messages: Membrane

2714036:G6534 RS08015
gene id: 2714036:G6534_RS08015
uniprot id: A0A7L7L0E3
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Homodimer.
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II ManXYZ PTS system is involved in mannose transport.

2714036:G6534 RS04425
gene id: 2714036:G6534_RS04425
uniprot id: A0A7L7KX39
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

2714036:G6534 RS09335
gene id: 2714036:G6534_RS09335
uniprot id: A0A7L7KZM1
names: Similarity
messages: Belongs to the SIS family. AgaS subfamily.

2714036:G6534 RS03340
gene id: 2714036:G6534_RS03340
uniprot id: A0A7L7KV58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

2714036:G6534 RS06785
gene id: 2714036:G6534_RS06785
uniprot id: A0A7L7KYA9
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

2714036:G6534 RS04025
gene id: 2714036:G6534_RS04025
uniprot id: A0A7L7KYH5
names: Function
names: Similarity
names: Subunit
messages: A non-essential component of RNA polymerase (RNAP).
messages: Belongs to the RNA polymerase subunit epsilon family.
messages: RNAP is composed of a core of 2 alpha, a beta and a beta' subunit. The core is associated with a delta subunit, and at least one of epsilon or omega. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

2714036:G6534 RS07855
gene id: 2714036:G6534_RS07855
uniprot id: A0A7L7KXK8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

2714036:G6534 RS04405
gene id: 2714036:G6534_RS04405
uniprot id: A0A7L7L0S5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.
messages: Membrane

2714036:G6534 RS11730
gene id: 2714036:G6534_RS11730
uniprot id: A0A7L7KZN5
names: Similarity
messages: Belongs to the Nudix hydrolase family.

2714036:G6534 RS06690
gene id: 2714036:G6534_RS06690
uniprot id: A0A7L7KZ88
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

2714036:G6534 RS01500
gene id: 2714036:G6534_RS01500
uniprot id: A0A7L7KUC1
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

2714036:G6534 RS03105
gene id: 2714036:G6534_RS03105
uniprot id: A0A7L7KV40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LTA synthase family.
messages: Cell membrane
messages: Membrane

2714036:G6534 RS06235
gene id: 2714036:G6534_RS06235
uniprot id: A0A7L7KWT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family.
messages: Membrane

2714036:G6534 RS05075
gene id: 2714036:G6534_RS05075
uniprot id: A0A7L7KXG2
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

2714036:G6534 RS10300
gene id: 2714036:G6534_RS10300
uniprot id: A0A7L7KZV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

2714036:G6534 RS04840
gene id: 2714036:G6534_RS04840
uniprot id: A0A7L7KWZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GRP transporter (TC 2.A.7.5) family.
messages: Cell membrane
messages: Membrane

2714036:G6534 RS01450
gene id: 2714036:G6534_RS01450
uniprot id: A0A7L7KUQ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. Xpt subfamily.
messages: Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.
messages: Cytoplasm
messages: Homodimer.

2714036:G6534 RS01340
gene id: 2714036:G6534_RS01340
uniprot id: A0A7L7KUN8
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 26 family. TagA/TarA subfamily.
messages: Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid.

2714036:G6534 RS07065
gene id: 2714036:G6534_RS07065
uniprot id: A0A7L7KXC8
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.

2714036:G6534 RS02905
gene id: 2714036:G6534_RS02905
uniprot id: A0A7L7KXB6
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

2714036:G6534 RS04785
gene id: 2714036:G6534_RS04785
uniprot id: A0A7L7KYY1
names: Similarity
messages: Belongs to the ClpX chaperone family. HslU subfamily.

2714036:G6534 RS01545
gene id: 2714036:G6534_RS01545
uniprot id: A0A7L7KVR6
names: Similarity
messages: Belongs to the DEAD box helicase family.

2714036:G6534 RS08570
gene id: 2714036:G6534_RS08570
uniprot id: A0A7L7KY16
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

2714036:G6534 RS03555
gene id: 2714036:G6534_RS03555
uniprot id: A0A7L7KW79
names: Similarity
messages: Belongs to the peptidase C69 family.

2714036:G6534 RS00425
gene id: 2714036:G6534_RS00425
uniprot id: A0A7L7KUV1
names: Similarity
messages: Belongs to the universal stress protein A family.

2714036:G6534 RS03495
gene id: 2714036:G6534_RS03495
uniprot id: A0A7L7KW72
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

2714036:G6534 RS01785
gene id: 2714036:G6534_RS01785
uniprot id: A0A7L7KVX8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

2714036:G6534 RS05810
gene id: 2714036:G6534_RS05810
uniprot id: A0A7L7KXI0
names: Similarity
messages: Belongs to the glycosyl hydrolase 25 family.

2714036:G6534 RS04950
gene id: 2714036:G6534_RS04950
uniprot id: A0A7L7KW13
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

2714036:G6534 RS07570
gene id: 2714036:G6534_RS07570
uniprot id: A0A7L7L086
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

2714036:G6534 RS04335
gene id: 2714036:G6534_RS04335
uniprot id: A0A7L7KX58
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

2714036:G6534 RS00585
gene id: 2714036:G6534_RS00585
uniprot id: A0A7L7KUX6
names: Similarity
messages: Belongs to the TPP enzyme family.

2714036:G6534 RS00210
gene id: 2714036:G6534_RS00210
uniprot id: A0A7L7KTQ3
names: Subcellular Location Annotation
messages: Membrane

2714036:G6534 RS04120
gene id: 2714036:G6534_RS04120
uniprot id: A0A7L7KVZ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

2714036:G6534 RS11605
gene id: 2714036:G6534_RS11605
uniprot id: A0A7L7L0K9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2714036:G6534 RS07835
gene id: 2714036:G6534_RS07835
uniprot id: A0A7L7KXL8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

2714036:G6534 RS10945
gene id: 2714036:G6534_RS10945
uniprot id: A0A7L7L140
names: Similarity
messages: Belongs to the ABC transporter superfamily.

2714036:G6534 RS09255
gene id: 2714036:G6534_RS09255
uniprot id: A0A7L7KYD0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of a set of proteins in which some residues (ACT_SITE, NP_BIND, REGION and BINDING) are not conserved.

2714036:G6534 RS00590
gene id: 2714036:G6534_RS00590
uniprot id: A0A7L7KTW4
names: Similarity
messages: Belongs to the phD/YefM antitoxin family.

2714036:G6534 RS08700
gene id: 2714036:G6534_RS08700
uniprot id: A0A7L7KY46
names: Similarity
messages: Belongs to the peptidase C40 family.

2714036:G6534 RS05110
gene id: 2714036:G6534_RS05110
uniprot id: A0A7L7KX56
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

2714036:G6534 RS08490
gene id: 2714036:G6534_RS08490
uniprot id: A0A7L7L089
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSP33 family.
messages: Cytoplasm
messages: Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.
messages: Under oxidizing conditions two disulfide bonds are formed involving the reactive cysteines. Under reducing conditions zinc is bound to the reactive cysteines and the protein is inactive.

2714036:G6534 RS10345
gene id: 2714036:G6534_RS10345
uniprot id: A0A7L7L0Z0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

2714036:G6534 RS10870
gene id: 2714036:G6534_RS10870
uniprot id: A0A7L7KZ71
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
messages: Tetramer of two alpha and two beta subunits.

2714036:G6534 RS11465
gene id: 2714036:G6534_RS11465
uniprot id: A0A7L7L1A7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

2714036:G6534 RS06455
gene id: 2714036:G6534_RS06455
uniprot id: A0A7L7KXT8
names: Similarity
messages: Belongs to the GARS family.

2714036:G6534 RS00250
gene id: 2714036:G6534_RS00250
uniprot id: A0A7L7KV61
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

2714036:G6534 RS02560
gene id: 2714036:G6534_RS02560
uniprot id: A0A7L7KXT3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LPG synthase family.
messages: Catalyzes the transfer of a lysyl group from L-lysyl-tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms.
messages: Cell membrane
messages: Membrane

2714036:G6534 RS08270
gene id: 2714036:G6534_RS08270
uniprot id: A0A7L7L0H0
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

2714036:G6534 RS00475
gene id: 2714036:G6534_RS00475
uniprot id: A0A7L7KTZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

2714036:G6534 RS02840
gene id: 2714036:G6534_RS02840
uniprot id: A0A7L7L0P1
names: Function
messages: Required for transformation and DNA binding.

2714036:G6534 RS01650
gene id: 2714036:G6534_RS01650
uniprot id: A0A7L7KUE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

2714036:G6534 RS08815
gene id: 2714036:G6534_RS08815
uniprot id: A0A7L7KY87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

2714036:G6534 RS08245
gene id: 2714036:G6534_RS08245
uniprot id: A0A7L7KXV6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

2714036:G6534 RS03940
gene id: 2714036:G6534_RS03940
uniprot id: A0A7L7KVG8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SepF family.
messages: Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
messages: Cytoplasm
messages: Homodimer. Interacts with FtsZ.

2714036:G6534 RS04035
gene id: 2714036:G6534_RS04035
uniprot id: A0A7L7KVK5
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

2714036:G6534 RS06600
gene id: 2714036:G6534_RS06600
uniprot id: A0A7L7KWY5
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

2714036:G6534 RS08455
gene id: 2714036:G6534_RS08455
uniprot id: A0A7L7KZ49
names: Similarity
messages: Belongs to the ClpA/ClpB family.

2714036:G6534 RS00880
gene id: 2714036:G6534_RS00880
uniprot id: A0A7L7KU11
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chloramphenicol acetyltransferase family.
messages: Homotrimer.
messages: This enzyme is an effector of chloramphenicol resistance in bacteria.

2714036:G6534 RS03915
gene id: 2714036:G6534_RS03915
uniprot id: A0A7L7KVJ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

2714036:G6534 RS02540
gene id: 2714036:G6534_RS02540
uniprot id: A0A7L7KZQ1
names: Similarity
messages: Belongs to the DCK/DGK family.

2714036:G6534 RS01435
gene id: 2714036:G6534_RS01435
uniprot id: A0A7L7KVP7
names: Subcellular Location Annotation
messages: Cytoplasm

2714036:G6534 RS03130
gene id: 2714036:G6534_RS03130
uniprot id: A0A7L7KXF3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the branched chain amino acid transporter family.
messages: Cell membrane
messages: Component of the transport system for branched-chain amino acids.
messages: Membrane

2714036:G6534 RS02500
gene id: 2714036:G6534_RS02500
uniprot id: A0A7L7KUX1
names: Subcellular Location Annotation
messages: Membrane

2714036:G6534 RS06255
gene id: 2714036:G6534_RS06255
uniprot id: A0A7L7KZ16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

2714036:G6534 RS07805
gene id: 2714036:G6534_RS07805
uniprot id: A0A7L7L0B6
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

2714036:G6534 RS06635
gene id: 2714036:G6534_RS06635
uniprot id: A0A7L7KX09
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

2714036:G6534 RS04635
gene id: 2714036:G6534_RS04635
uniprot id: A0A7L7L034
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ScpB family.
messages: Cytoplasm
messages: Homodimer. Homodimerization may be required to stabilize the binding of ScpA to the Smc head domains. Component of a cohesin-like complex composed of ScpA, ScpB and the Smc homodimer, in which ScpA and ScpB bind to the head domain of Smc. The presence of the three proteins is required for the association of the complex with DNA.
messages: Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves.

2714036:G6534 RS10700
gene id: 2714036:G6534_RS10700
uniprot id: A0A7L7L0W1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

2714036:G6534 RS01965
gene id: 2714036:G6534_RS01965
uniprot id: A0A7L7KUK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

2714036:G6534 RS01325
gene id: 2714036:G6534_RS01325
uniprot id: A0A7L7KVN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family.
messages: Membrane

2714036:G6534 RS11670
gene id: 2714036:G6534_RS11670
uniprot id: A0A7L7KZQ9
names: Subcellular Location Annotation
messages: Membrane

2714036:G6534 RS07560
gene id: 2714036:G6534_RS07560
uniprot id: A0A7L7L1M5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

2714036:G6534 RS02810
gene id: 2714036:G6534_RS02810
uniprot id: A0A7L7KUZ8
names: Subcellular Location Annotation
messages: Membrane

2714036:G6534 RS08555
gene id: 2714036:G6534_RS08555
uniprot id: A0A7L7KXY9
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

2714036:G6534 RS07015
gene id: 2714036:G6534_RS07015
uniprot id: A0A7L7KXB9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

2714036:G6534 RS02160
gene id: 2714036:G6534_RS02160
uniprot id: A0A7L7KUR4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2714036:G6534 RS04665
gene id: 2714036:G6534_RS04665
uniprot id: A0A7L7KXC3
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

2714036:G6534 RS09145
gene id: 2714036:G6534_RS09145
uniprot id: A0A7L7KYE6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane

2714036:G6534 RS05450
gene id: 2714036:G6534_RS05450
uniprot id: A0A7L7KWE6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

2714036:G6534 RS03820
gene id: 2714036:G6534_RS03820
uniprot id: A0A7L7KYD8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

2714036:G6534 RS06360
gene id: 2714036:G6534_RS06360
uniprot id: A0A7L7KWV5
names: Similarity
messages: Belongs to the ribF family.

2714036:G6534 RS04620
gene id: 2714036:G6534_RS04620
uniprot id: A0A7L7L0K4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

2714036:G6534 RS07915
gene id: 2714036:G6534_RS07915
uniprot id: A0A7L7KYI9
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

2714036:G6534 RS04030
gene id: 2714036:G6534_RS04030
uniprot id: A0A7L7KWI1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

2714036:G6534 RS03800
gene id: 2714036:G6534_RS03800
uniprot id: A0A7L7KXS4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

2714036:G6534 RS02475
gene id: 2714036:G6534_RS02475
uniprot id: A0A7L7KW61
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

2714036:G6534 RS04765
gene id: 2714036:G6534_RS04765
uniprot id: A0A7L7KW76
names: Similarity
messages: Belongs to the DprA/Smf family.

2714036:G6534 RS01095
gene id: 2714036:G6534_RS01095
uniprot id: A0A7L7KVJ5
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

2714036:G6534 RS03165
gene id: 2714036:G6534_RS03165
uniprot id: A0A7L7KV49
names: Function
messages: Component of the dihydroxyacetone kinase complex, which is responsible for the phosphoenolpyruvate (PEP)-dependent phosphorylation of dihydroxyacetone. DhaM serves as the phosphoryl donor. Is phosphorylated by phosphoenolpyruvate in an EI- and HPr-dependent reaction, and a phosphorelay system on histidine residues finally leads to phosphoryl transfer to DhaL and dihydroxyacetone.

2714036:G6534 RS02185
gene id: 2714036:G6534_RS02185
uniprot id: A0A7L7KUN9
names: Similarity
messages: Belongs to the cycloisomerase 2 family.

2714036:G6534 RS07585
gene id: 2714036:G6534_RS07585
uniprot id: A0A7L7KXH2
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

2714036:G6534 RS08285
gene id: 2714036:G6534_RS08285
uniprot id: A0A7L7KXV9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

2714036:G6534 RS03205
gene id: 2714036:G6534_RS03205
uniprot id: A0A7L7KY20
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

2714036:G6534 RS03785
gene id: 2714036:G6534_RS03785
uniprot id: A0A7L7KVE0
names: Subcellular Location Annotation
messages: Membrane

2714036:G6534 RS09135
gene id: 2714036:G6534_RS09135
uniprot id: A0A7L7KYC3
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

2714036:G6534 RS06730
gene id: 2714036:G6534_RS06730
uniprot id: A0A7L7KX28
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

2714036:G6534 RS03695
gene id: 2714036:G6534_RS03695
uniprot id: A0A7L7KXQ4
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

2714036:G6534 RS02800
gene id: 2714036:G6534_RS02800
uniprot id: A0A7L7KVB1
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

2714036:G6534 RS08240
gene id: 2714036:G6534_RS08240
uniprot id: A0A7L7KZ09
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

2714036:G6534 RS01705
gene id: 2714036:G6534_RS01705
uniprot id: A0A7L7KVU6
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

2714036:G6534 RS02965
gene id: 2714036:G6534_RS02965
uniprot id: A0A7L7KXC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nlpA lipoprotein family.
messages: Membrane

2714036:G6534 RS00375
gene id: 2714036:G6534_RS00375
uniprot id: A0A7L7KTT3
names: Similarity
messages: Belongs to the universal stress protein A family.

2714036:G6534 RS02370
gene id: 2714036:G6534_RS02370
uniprot id: A0A7L7KX44
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

2714036:G6534 RS01950
gene id: 2714036:G6534_RS01950
uniprot id: A0A7L7KXG9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
messages: This function is generally fulfilled by the C-terminal part of HisG, which is missing in some bacteria such as this one.

2714036:G6534 RS04175
gene id: 2714036:G6534_RS04175
uniprot id: A0A7L7KZU7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

2714036:G6534 RS00180
gene id: 2714036:G6534_RS00180
uniprot id: A0A7L7KU49
names: Similarity
messages: Belongs to the Fur family.

2714036:G6534 RS03080
gene id: 2714036:G6534_RS03080
uniprot id: A0A7L7KVF7
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.

2714036:G6534 RS03705
gene id: 2714036:G6534_RS03705
uniprot id: A0A7L7KWS8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.

2714036:G6534 RS03725
gene id: 2714036:G6534_RS03725
uniprot id: A0A7L7L0J9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

2714036:G6534 RS00525
gene id: 2714036:G6534_RS00525
uniprot id: A0A7L7KTZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

2714036:G6534 RS05365
gene id: 2714036:G6534_RS05365
uniprot id: A0A7L7KYM7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

2714036:G6534 RS01055
gene id: 2714036:G6534_RS01055
uniprot id: A0A7L7KZP7
names: Function
names: Similarity
messages: Belongs to the CpsD/CapB family.
messages: Involved in the regulation of capsular polysaccharide biosynthesis. Autophosphorylation of CpsD attenuates its activity and reduces the level of encapsulation. May be part of a complex that directs the coordinated polymerization and export to the cell surface of the capsular polysaccharide.

2714036:G6534 RS09165
gene id: 2714036:G6534_RS09165
uniprot id: A0A7L7KZ72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0053 family.
messages: Membrane

2714036:G6534 RS03735
gene id: 2714036:G6534_RS03735
uniprot id: A0A7L7KVD1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

2714036:G6534 RS05465
gene id: 2714036:G6534_RS05465
uniprot id: A0A7L7KYP3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

2714036:G6534 RS08320
gene id: 2714036:G6534_RS08320
uniprot id: A0A7L7KXU4
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

2714036:G6534 RS06620
gene id: 2714036:G6534_RS06620
uniprot id: A0A7L7KX03
names: Similarity
messages: Belongs to the asp23 family.

2714036:G6534 RS06265
gene id: 2714036:G6534_RS06265
uniprot id: A0A7L7KY63
names: Function
names: Similarity
messages: Abolishes the inhibitory effect of tetracyclin on protein synthesis by a non-covalent modification of the ribosomes.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.

2714036:G6534 RS07530
gene id: 2714036:G6534_RS07530
uniprot id: A0A7L7KYN3
names: Similarity
messages: Belongs to the UPF0297 family.

2714036:G6534 RS01235
gene id: 2714036:G6534_RS01235
uniprot id: A0A7L7KV90
names: Subcellular Location Annotation
messages: Membrane

2714036:G6534 RS11220
gene id: 2714036:G6534_RS11220
uniprot id: A0A7L7KZM3
names: Similarity
messages: Belongs to the aldolase LacD family.

2714036:G6534 RS06440
gene id: 2714036:G6534_RS06440
uniprot id: A0A7L7KY90
names: Similarity
messages: Belongs to the UPF0213 family.

2714036:G6534 RS02005
gene id: 2714036:G6534_RS02005
uniprot id: A0A7L7KXH9
names: Similarity
messages: Belongs to the UPF0111 family.

2714036:G6534 RS06920
gene id: 2714036:G6534_RS06920
uniprot id: A0A7L7KX46
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TmcAL family.
messages: Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of elongator tRNA(Met), using acetate and ATP as substrates. First activates an acetate ion to form acetyladenylate (Ac-AMP) and then transfers the acetyl group to tRNA to form ac(4)C34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2714036:G6534 RS04485
gene id: 2714036:G6534_RS04485
uniprot id: A0A7L7KY60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Membrane

2714036:G6534 RS00505
gene id: 2714036:G6534_RS00505
uniprot id: A0A7L7KTV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

2714036:G6534 RS06850
gene id: 2714036:G6534_RS06850
uniprot id: A0A7L7KX50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transpeptidase family.
messages: Cell membrane
messages: Membrane

2714036:G6534 RS02180
gene id: 2714036:G6534_RS02180
uniprot id: A0A7L7KUP7
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

2714036:G6534 RS09450
gene id: 2714036:G6534_RS09450
uniprot id: A0A7L7KYG8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase D family. Cardiolipin synthase subfamily.
messages: Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
messages: Cell membrane
messages: Membrane

2714036:G6534 RS01625
gene id: 2714036:G6534_RS01625
uniprot id: A0A7L7KUH5
names: Similarity
messages: Belongs to the acetyltransferase family.

2714036:G6534 RS00160
gene id: 2714036:G6534_RS00160
uniprot id: A0A7L7KTP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

2714036:G6534 RS00205
gene id: 2714036:G6534_RS00205
uniprot id: A0A7L7KUR3
names: Similarity
messages: Belongs to the Fur family.

2714036:G6534 RS07930
gene id: 2714036:G6534_RS07930
uniprot id: A0A7L7KYU7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose 5-phosphate isomerase family.
messages: Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
messages: Homodimer.

2714036:G6534 RS04115
gene id: 2714036:G6534_RS04115
uniprot id: A0A7L7KXY5
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

2714036:G6534 RS04040
gene id: 2714036:G6534_RS04040
uniprot id: A0A7L7KZT5
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

2714036:G6534 RS08485
gene id: 2714036:G6534_RS08485
uniprot id: A0A7L7KXZ8
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

2714036:G6534 RS05485
gene id: 2714036:G6534_RS05485
uniprot id: A0A7L7KZA7
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

2714036:G6534 RS07875
gene id: 2714036:G6534_RS07875
uniprot id: A0A7L7KXM5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

2714036:G6534 RS06910
gene id: 2714036:G6534_RS06910
uniprot id: A0A7L7KX99
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

2714036:G6534 RS04260
gene id: 2714036:G6534_RS04260
uniprot id: A0A7L7KX07
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane.

2714036:G6534 RS03420
gene id: 2714036:G6534_RS03420
uniprot id: A0A7L7KWM7
names: Subcellular Location Annotation
messages: Membrane

2714036:G6534 RS10685
gene id: 2714036:G6534_RS10685
uniprot id: A0A7L7KZ48
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2714036:G6534 RS02940
gene id: 2714036:G6534_RS02940
uniprot id: A0A7L7KV12
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

2714036:G6534 RS03740
gene id: 2714036:G6534_RS03740
uniprot id: A0A7L7KWQ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

2714036:G6534 RS06405
gene id: 2714036:G6534_RS06405
uniprot id: A0A7L7KWW0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

2714036:G6534 RS06840
gene id: 2714036:G6534_RS06840
uniprot id: A0A7L7KX47
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

2714036:G6534 RS05005
gene id: 2714036:G6534_RS05005
uniprot id: A0A7L7KX30
names: Similarity
messages: Belongs to the EamA transporter family.

2714036:G6534 RS04720
gene id: 2714036:G6534_RS04720
uniprot id: A0A7L7KXD6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2714036:G6534 RS03710
gene id: 2714036:G6534_RS03710
uniprot id: A0A7L7KVF1
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

2714036:G6534 RS07700
gene id: 2714036:G6534_RS07700
uniprot id: A0A7L7KXJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transcriptional regulatory Rex family.
messages: Cytoplasm
messages: Homodimer.
messages: Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.

2714036:G6534 RS02405
gene id: 2714036:G6534_RS02405
uniprot id: A0A7L7KUU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. EmrB family.
messages: Cell membrane
messages: Membrane

2714036:G6534 RS06605
gene id: 2714036:G6534_RS06605
uniprot id: A0A7L7KZS8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

2714036:G6534 RS04240
gene id: 2714036:G6534_RS04240
uniprot id: A0A7L7KYM5
names: Cofactor
messages: Binds 1 Mg(2+) ion per trimer.

2714036:G6534 RS05185
gene id: 2714036:G6534_RS05185
uniprot id: A0A7L7KXI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

2714036:G6534 RS04075
gene id: 2714036:G6534_RS04075
uniprot id: A0A7L7KVL8
names: Subcellular Location Annotation
messages: Membrane

2714036:G6534 RS07470
gene id: 2714036:G6534_RS07470
uniprot id: A0A7L7KXF2
names: Function
messages: Global transcriptional regulator of carbon catabolite repression (CCR) and carbon catabolite activation (CCA), which ensures optimal energy usage under diverse conditions.

2714036:G6534 RS10765
gene id: 2714036:G6534_RS10765
uniprot id: A0A7L7L0G2
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

2714036:G6534 RS08315
gene id: 2714036:G6534_RS08315
uniprot id: A0A7L7L007
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

2714036:G6534 RS01790
gene id: 2714036:G6534_RS01790
uniprot id: A0A7L7KUJ8
names: Similarity
messages: Belongs to the UPF0374 family.

2714036:G6534 RS06650
gene id: 2714036:G6534_RS06650
uniprot id: A0A7L7KYD1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LuxS family.
messages: Binds 1 Fe cation per subunit.
messages: Homodimer.
messages: Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).

2714036:G6534 RS02125
gene id: 2714036:G6534_RS02125
uniprot id: A0A7L7KUN1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArsC family. Spx subfamily.
messages: Cytoplasm
messages: Global transcriptional regulator that plays a key role in stress response and exerts either positive or negative regulation of genes. Acts by interacting with the C-terminal domain of the alpha subunit of the RNA polymerase (RNAP). This interaction can enhance binding of RNAP to the promoter region of target genes and stimulate their transcription, or block interaction of RNAP with activator.
messages: Interacts with the C-terminal domain of the alpha subunit of the RNAP.

2714036:G6534 RS00850
gene id: 2714036:G6534_RS00850
uniprot id: A0A7L7KU43
names: Similarity
messages: Belongs to the glutathione peroxidase family.

2714036:G6534 RS07140
gene id: 2714036:G6534_RS07140
uniprot id: A0A7L7KY62
names: Similarity
messages: Belongs to the carbamate kinase family.

2714036:G6534 RS08540
gene id: 2714036:G6534_RS08540
uniprot id: A0A7L7L0A0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LDH/MDH superfamily. LDH family.
messages: Catalyzes the conversion of lactate to pyruvate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2714036:G6534 RS04460
gene id: 2714036:G6534_RS04460
uniprot id: A0A7L7KWS0
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

2714036:G6534 RS01925
gene id: 2714036:G6534_RS01925
uniprot id: A0A7L7KUJ5
names: Similarity
messages: Belongs to the sigma-54 factor family.

2714036:G6534 RS01060
gene id: 2714036:G6534_RS01060
uniprot id: A0A7L7KVL0
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. CpsB/CapC family.

2714036:G6534 RS06700
gene id: 2714036:G6534_RS06700
uniprot id: A0A7L7KYE2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

2714036:G6534 RS09155
gene id: 2714036:G6534_RS09155
uniprot id: A0A7L7KYB2
names: Similarity
messages: Belongs to the 6-phosphogluconate dehydrogenase family.

2714036:G6534 RS04140
gene id: 2714036:G6534_RS04140
uniprot id: A0A7L7KWL0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

2714036:G6534 RS06520
gene id: 2714036:G6534_RS06520
uniprot id: A0A7L7KWY1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

2714036:G6534 RS03065
gene id: 2714036:G6534_RS03065
uniprot id: A0A7L7KWD2
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

2714036:G6534 RS01535
gene id: 2714036:G6534_RS01535
uniprot id: A0A7L7KUC5
names: Subcellular Location Annotation
messages: Membrane

2714036:G6534 RS04195
gene id: 2714036:G6534_RS04195
uniprot id: A0A7L7KWL9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lactate permease family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Uptake of L-lactate across the membrane. Can also transport D-lactate and glycolate.

2714036:G6534 RS01555
gene id: 2714036:G6534_RS01555
uniprot id: A0A7L7KUD2
names: Similarity
messages: Belongs to the thioester dehydratase family. FabZ subfamily.

2714036:G6534 RS05865
gene id: 2714036:G6534_RS05865
uniprot id: A0A7L7KWM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

2714036:G6534 RS06570
gene id: 2714036:G6534_RS06570
uniprot id: A0A7L7KWZ1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

2714036:G6534 RS03650
gene id: 2714036:G6534_RS03650
uniprot id: A0A7L7KWR9
names: Similarity
messages: Belongs to the flavin oxidoreductase frp family.

2714036:G6534 RS08300
gene id: 2714036:G6534_RS08300
uniprot id: A0A7L7L060
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

2714036:G6534 RS07975
gene id: 2714036:G6534_RS07975
uniprot id: A0A7L7KXP8
names: Subcellular Location Annotation
messages: Membrane

2714036:G6534 RS08040
gene id: 2714036:G6534_RS08040
uniprot id: A0A7L7KXQ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PstS family.
messages: Cell membrane
messages: Involved in the system for phosphate transport across the cytoplasmic membrane.
messages: Membrane
messages: Part of the ABC transporter complex PstSACB involved in phosphate import.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

2714036:G6534 RS05750
gene id: 2714036:G6534_RS05750
uniprot id: A0A7L7KWJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

2714036:G6534 RS00510
gene id: 2714036:G6534_RS00510
uniprot id: A0A7L7KW42
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

2714036:G6534 RS06965
gene id: 2714036:G6534_RS06965
uniprot id: A0A7L7KYJ2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

2714036:G6534 RS03910
gene id: 2714036:G6534_RS03910
uniprot id: A0A7L7KWX7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

2714036:G6534 RS01445
gene id: 2714036:G6534_RS01445
uniprot id: A0A7L7KWF6
names: Similarity
messages: Belongs to the glycosyl hydrolase 73 family.

2714036:G6534 RS07410
gene id: 2714036:G6534_RS07410
uniprot id: A0A7L7KYA2
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the ferredoxin--NADP reductase type 2 family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2714036:G6534 RS01490
gene id: 2714036:G6534_RS01490
uniprot id: A0A7L7KUC0
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

2714036:G6534 RS03750
gene id: 2714036:G6534_RS03750
uniprot id: A0A7L7KXR4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

2714036:G6534 RS03490
gene id: 2714036:G6534_RS03490
uniprot id: A0A7L7KY73
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

2714036:G6534 RS04630
gene id: 2714036:G6534_RS04630
uniprot id: A0A7L7KVW8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ScpA family.
messages: Component of a cohesin-like complex composed of ScpA, ScpB and the Smc homodimer, in which ScpA and ScpB bind to the head domain of Smc. The presence of the three proteins is required for the association of the complex with DNA.
messages: Cytoplasm
messages: Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves.

2714036:G6534 RS08310
gene id: 2714036:G6534_RS08310
uniprot id: A0A7L7KZ66
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

2714036:G6534 RS06315
gene id: 2714036:G6534_RS06315
uniprot id: A0A7L7KZ22
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

2714036:G6534 RS05150
gene id: 2714036:G6534_RS05150
uniprot id: A0A7L7KW99
names: Function
names: Similarity
names: Subunit
messages: Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
messages: Homodimer and homohexamer; in equilibrium.
messages: Regulates transcriptional attenuation of the pyrimidine nucleotide (pyr) operon by binding in a uridine-dependent manner to specific sites on pyr mRNA. This disrupts an antiterminator hairpin in the RNA and favors formation of a downstream transcription terminator, leading to a reduced expression of downstream genes.

2714036:G6534 RS07510
gene id: 2714036:G6534_RS07510
uniprot id: A0A7L7L076
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
messages: Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
messages: Homodimer.

2714036:G6534 RS08690
gene id: 2714036:G6534_RS08690
uniprot id: A0A7L7KY28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0014 family.
messages: Membrane

2714036:G6534 RS11255
gene id: 2714036:G6534_RS11255
uniprot id: A0A7L7KZE7
names: Subcellular Location Annotation
messages: Membrane

2714036:G6534 RS02165
gene id: 2714036:G6534_RS02165
uniprot id: A0A7L7KXK5
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

2714036:G6534 RS02520
gene id: 2714036:G6534_RS02520
uniprot id: A0A7L7KUU9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

2714036:G6534 RS10725
gene id: 2714036:G6534_RS10725
uniprot id: A0A7L7L105
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

2714036:G6534 RS00945
gene id: 2714036:G6534_RS00945
uniprot id: A0A7L7KVI9
names: Similarity
messages: Belongs to the EamA transporter family.

2714036:G6534 RS04940
gene id: 2714036:G6534_RS04940
uniprot id: A0A7L7KX19
names: Cofactor
messages: Binds 2 manganese ions per subunit.

2714036:G6534 RS01495
gene id: 2714036:G6534_RS01495
uniprot id: A0A7L7KVQ7
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

2714036:G6534 RS07225
gene id: 2714036:G6534_RS07225
uniprot id: A0A7L7KXC0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

2714036:G6534 RS03470
gene id: 2714036:G6534_RS03470
uniprot id: A0A7L7KVM9
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

2714036:G6534 RS02345
gene id: 2714036:G6534_RS02345
uniprot id: A0A7L7KVS4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

2714036:G6534 RS06640
gene id: 2714036:G6534_RS06640
uniprot id: A0A7L7KZ80
names: Similarity
messages: Belongs to the peptidase C56 family.

2714036:G6534 RS07490
gene id: 2714036:G6534_RS07490
uniprot id: A0A7L7KZR2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

2714036:G6534 RS04225
gene id: 2714036:G6534_RS04225
uniprot id: A0A7L7KW14
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

2714036:G6534 RS07435
gene id: 2714036:G6534_RS07435
uniprot id: A0A7L7KXE6
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

2714036:G6534 RS01760
gene id: 2714036:G6534_RS01760
uniprot id: A0A7L7KVV5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 32 family.
messages: Cytoplasm
messages: Enables the bacterium to metabolize sucrose as a sole carbon source.

2714036:G6534 RS00280
gene id: 2714036:G6534_RS00280
uniprot id: A0A7L7KTR8
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

2714036:G6534 RS04820
gene id: 2714036:G6534_RS04820
uniprot id: A0A7L7KW92
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type II topoisomerase family. ParE type 2 subfamily.
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

2714036:G6534 RS02310
gene id: 2714036:G6534_RS02310
uniprot id: A0A7L7L1H0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

2714036:G6534 RS04815
gene id: 2714036:G6534_RS04815
uniprot id: A0A7L7KYC5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably interacts with PlsX.

2714036:G6534 RS09400
gene id: 2714036:G6534_RS09400
uniprot id: A0A7L7KZM8
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.

2714036:G6534 RS03390
gene id: 2714036:G6534_RS03390
uniprot id: A0A7L7KV84
names: Similarity
names: Subunit
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.
messages: Homotetramer.

2714036:G6534 RS11640
gene id: 2714036:G6534_RS11640
uniprot id: A0A7L7L0F8
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.

2714036:G6534 RS05105
gene id: 2714036:G6534_RS05105
uniprot id: A0A7L7KZ42
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2714036:G6534 RS08090
gene id: 2714036:G6534_RS08090
uniprot id: A0A7L7KXR8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAD-like hydrolase superfamily. PhnX family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Involved in phosphonate degradation.

2714036:G6534 RS00285
gene id: 2714036:G6534_RS00285
uniprot id: A0A7L7KV57
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

2714036:G6534 RS04640
gene id: 2714036:G6534_RS04640
uniprot id: A0A7L7KVV2
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

2714036:G6534 RS06760
gene id: 2714036:G6534_RS06760
uniprot id: A0A7L7KX18
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

2714036:G6534 RS04245
gene id: 2714036:G6534_RS04245
uniprot id: A0A7L7KWN1
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

2714036:G6534 RS04595
gene id: 2714036:G6534_RS04595
uniprot id: A0A7L7KW59
names: Similarity
messages: Belongs to the pyruvate kinase family.
messages: In the C-terminal section; belongs to the PEP-utilizing enzyme family.

2714036:G6534 RS01735
gene id: 2714036:G6534_RS01735
uniprot id: A0A7L7KUI6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. GalK subfamily.
messages: Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P).
messages: Cytoplasm

2714036:G6534 RS02780
gene id: 2714036:G6534_RS02780
uniprot id: A0A7L7KUX2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

2714036:G6534 RS02340
gene id: 2714036:G6534_RS02340
uniprot id: A0A7L7KXN9
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HPrK/P family.
messages: Both phosphorylation and phosphorolysis are carried out by the same active site and suggest a common mechanism for both reactions.
messages: Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr). The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK/P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport: it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion.
messages: Homohexamer.
messages: The Walker A ATP-binding motif also binds Pi and PPi.

2714036:G6534 RS07525
gene id: 2714036:G6534_RS07525
uniprot id: A0A7L7KXG8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

2714036:G6534 RS07820
gene id: 2714036:G6534_RS07820
uniprot id: A0A7L7KXL5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

2714036:G6534 RS00075
gene id: 2714036:G6534_RS00075
uniprot id: A0A7L7KVW9
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

2714036:G6534 RS10570
gene id: 2714036:G6534_RS10570
uniprot id: A0A7L7KZ32
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

2714036:G6534 RS08260
gene id: 2714036:G6534_RS08260
uniprot id: A0A7L7KZ53
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex.
messages: Belongs to the ABC transporter superfamily. Energy-coupling factor EcfA family.
messages: Cell membrane
messages: Forms a stable energy-coupling factor (ECF) transporter complex composed of 2 membrane-embedded substrate-binding proteins (S component), 2 ATP-binding proteins (A component) and 2 transmembrane proteins (T component).
messages: Membrane

2714036:G6534 RS02390
gene id: 2714036:G6534_RS02390
uniprot id: A0A7L7KUV0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gluconeogenesis factor family.
messages: Cytoplasm
messages: Required for morphogenesis under gluconeogenic growth conditions.

2714036:G6534 RS06375
gene id: 2714036:G6534_RS06375
uniprot id: A0A7L7KY79
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

2714036:G6534 RS08400
gene id: 2714036:G6534_RS08400
uniprot id: A0A7L7KZ39
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

2714036:G6534 RS08385
gene id: 2714036:G6534_RS08385
uniprot id: A0A7L7KYT4
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

2714036:G6534 RS00965
gene id: 2714036:G6534_RS00965
uniprot id: A0A7L7KU28
names: Similarity
messages: Belongs to the TPP enzyme family.

2714036:G6534 RS02875
gene id: 2714036:G6534_RS02875
uniprot id: A0A7L7KVY8
names: Similarity
messages: In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
messages: In the N-terminal section; belongs to the aldehyde dehydrogenase family.

2714036:G6534 RS06365
gene id: 2714036:G6534_RS06365
uniprot id: A0A7L7KZ29
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

2714036:G6534 RS05845
gene id: 2714036:G6534_RS05845
uniprot id: A0A7L7KXZ3
names: Cofactor
messages: Binds 2 magnesium ions per subunit.

2714036:G6534 RS03850
gene id: 2714036:G6534_RS03850
uniprot id: A0A7L7KXT6
names: Similarity
messages: Belongs to the UPF0758 family.

2714036:G6534 RS08345
gene id: 2714036:G6534_RS08345
uniprot id: A0A7L7KZ30
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

2714036:G6534 RS01915
gene id: 2714036:G6534_RS01915
uniprot id: A0A7L7KUJ6
names: Subcellular Location Annotation
messages: cell wall

2714036:G6534 RS05705
gene id: 2714036:G6534_RS05705
uniprot id: A0A7L7KXG1
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

2714036:G6534 RS05095
gene id: 2714036:G6534_RS05095
uniprot id: A0A7L7KXM0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

2714036:G6534 RS11455
gene id: 2714036:G6534_RS11455
uniprot id: A0A7L7L0M3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2714036:G6534 RS01660
gene id: 2714036:G6534_RS01660
uniprot id: A0A7L7KUE9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

2714036:G6534 RS03000
gene id: 2714036:G6534_RS03000
uniprot id: A0A7L7KV19
names: Subcellular Location Annotation
messages: Membrane

2714036:G6534 RS03890
gene id: 2714036:G6534_RS03890
uniprot id: A0A7L7KWT5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

2714036:G6534 RS03045
gene id: 2714036:G6534_RS03045
uniprot id: A0A7L7KXZ1
names: Caution
names: Function
names: Similarity
messages: Belongs to the UbiX/PAD1 family.
messages: Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2714036:G6534 RS00015
gene id: 2714036:G6534_RS00015
uniprot id: A0A7L7KWK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0324 family.
messages: Cell membrane
messages: Membrane

2714036:G6534 RS07285
gene id: 2714036:G6534_RS07285
uniprot id: A0A7L7KYJ5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

2714036:G6534 RS08590
gene id: 2714036:G6534_RS08590
uniprot id: A0A7L7L0B3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2714036:G6534 RS08695
gene id: 2714036:G6534_RS08695
uniprot id: A0A7L7KZA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane

2714036:G6534 RS06745
gene id: 2714036:G6534_RS06745
uniprot id: A0A7L7KZA0
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

2714036:G6534 RS02240
gene id: 2714036:G6534_RS02240
uniprot id: A0A7L7KW35
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

2714036:G6534 RS04375
gene id: 2714036:G6534_RS04375
uniprot id: A0A7L7KVR1
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

2714036:G6534 RS05790
gene id: 2714036:G6534_RS05790
uniprot id: A0A7L7KWQ8
names: Similarity
messages: Belongs to the glycosyl hydrolase 25 family.

2714036:G6534 RS04135
gene id: 2714036:G6534_RS04135
uniprot id: A0A7L7KYJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

2714036:G6534 RS00300
gene id: 2714036:G6534_RS00300
uniprot id: A0A7L7KU67
names: Subcellular Location Annotation
messages: Membrane

2714036:G6534 RS08580
gene id: 2714036:G6534_RS08580
uniprot id: A0A7L7KZ74
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
messages: Part of the 50S ribosomal subunit.

2714036:G6534 RS00125
gene id: 2714036:G6534_RS00125
uniprot id: A0A7L7KVY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

2714036:G6534 RS05060
gene id: 2714036:G6534_RS05060
uniprot id: A0A7L7KW83
names: Similarity
messages: Belongs to the PemK/MazF family.

2714036:G6534 RS01260
gene id: 2714036:G6534_RS01260
uniprot id: A0A7L7KVM3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ApbE family.
messages: Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.
messages: Magnesium. Can also use manganese.

2714036:G6534 RS04865
gene id: 2714036:G6534_RS04865
uniprot id: A0A7L7KYD5
names: Subcellular Location Annotation
messages: Membrane

2714036:G6534 RS05045
gene id: 2714036:G6534_RS05045
uniprot id: A0A7L7KW81
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2714036:G6534 RS03955
gene id: 2714036:G6534_RS03955
uniprot id: A0A7L7KXV5
names: Subcellular Location Annotation
messages: Cytoplasm

2714036:G6534 RS05545
gene id: 2714036:G6534_RS05545
uniprot id: A0A7L7KXD3
names: Function
names: Subunit
messages: Catalyzes the conversion of a range of fructosamine 6-phosphates to glucose 6-phosphate and a free amino acid.
messages: Homooctamer.

2714036:G6534 RS02790
gene id: 2714036:G6534_RS02790
uniprot id: A0A7L7KUW8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the adenylate cyclase family. DacA/CdaA subfamily.
messages: Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably a homodimer.

2714036:G6534 RS00555
gene id: 2714036:G6534_RS00555
uniprot id: A0A7L7KTW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. EmrB family.
messages: Cell membrane
messages: Membrane

2714036:G6534 RS07815
gene id: 2714036:G6534_RS07815
uniprot id: A0A7L7KXL7
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

2714036:G6534 RS05640
gene id: 2714036:G6534_RS05640
uniprot id: A0A7L7KXV7
names: Similarity
messages: Belongs to the universal stress protein A family.

2714036:G6534 RS01160
gene id: 2714036:G6534_RS01160
uniprot id: A0A7L7KWB1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2714036:G6534 RS10495
gene id: 2714036:G6534_RS10495
uniprot id: A0A7L7L1B7
names: Similarity
messages: Belongs to the ThiD family.

2714036:G6534 RS07675
gene id: 2714036:G6534_RS07675
uniprot id: A0A7L7KYV5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

2714036:G6534 RS07850
gene id: 2714036:G6534_RS07850
uniprot id: A0A7L7KYY3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

2714036:G6534 RS06980
gene id: 2714036:G6534_RS06980
uniprot id: A0A7L7KZZ0
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2714036:G6534 RS03195
gene id: 2714036:G6534_RS03195
uniprot id: A0A7L7KWI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

2714036:G6534 RS08100
gene id: 2714036:G6534_RS08100
uniprot id: A0A7L7KXV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

2714036:G6534 RS05375
gene id: 2714036:G6534_RS05375
uniprot id: A0A7L7KXR5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

2714036:G6534 RS08915
gene id: 2714036:G6534_RS08915
uniprot id: A0A7L7KY84
names: Similarity
messages: Belongs to the DltD family.

2714036:G6534 RS04870
gene id: 2714036:G6534_RS04870
uniprot id: A0A7L7KWA5
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A lyase-type mechanism (elimination/hydration) is suggested for the cleavage of the lactyl ether bond of MurNAc 6-phosphate, with the formation of an alpha,beta-unsaturated aldehyde intermediate with (E)-stereochemistry, followed by the syn addition of water to give product.
messages: Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.
messages: Homodimer.
messages: Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate.

2714036:G6534 RS08405
gene id: 2714036:G6534_RS08405
uniprot id: A0A7L7KXY8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

2714036:G6534 RS07860
gene id: 2714036:G6534_RS07860
uniprot id: A0A7L7L0C3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

2714036:G6534 RS06885
gene id: 2714036:G6534_RS06885
uniprot id: A0A7L7KX54
names: Similarity
messages: Belongs to the acylphosphatase family.

2714036:G6534 RS01780
gene id: 2714036:G6534_RS01780
uniprot id: A0A7L7KUW5
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

2714036:G6534 RS07730
gene id: 2714036:G6534_RS07730
uniprot id: A0A7L7KXN1
names: Similarity
messages: Belongs to the UPF0237 family.

2714036:G6534 RS08750
gene id: 2714036:G6534_RS08750
uniprot id: A0A7L7KY57
names: Subcellular Location Annotation
messages: Membrane

2714036:G6534 RS08365
gene id: 2714036:G6534_RS08365
uniprot id: A0A7L7KZ75
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

2714036:G6534 RS06655
gene id: 2714036:G6534_RS06655
uniprot id: A0A7L7KWZ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nlpA lipoprotein family.
messages: Membrane

2714036:G6534 RS03435
gene id: 2714036:G6534_RS03435
uniprot id: A0A7L7KW67
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

2714036:G6534 RS03055
gene id: 2714036:G6534_RS03055
uniprot id: A0A7L7KV28
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2714036:G6534 RS02080
gene id: 2714036:G6534_RS02080
uniprot id: A0A7L7KW12
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

2714036:G6534 RS03120
gene id: 2714036:G6534_RS03120
uniprot id: A0A7L7KWE3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2714036:G6534 RS00775
gene id: 2714036:G6534_RS00775
uniprot id: A0A7L7KUE7
names: Function
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

2714036:G6534 RS07315
gene id: 2714036:G6534_RS07315
uniprot id: A0A7L7KYQ2
names: Function
names: Similarity
messages: Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Belongs to the organic radical-activating enzymes family.

2714036:G6534 RS05320
gene id: 2714036:G6534_RS05320
uniprot id: A0A7L7KWI0
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.
messages: Homohexamer.

2714036:G6534 RS06580
gene id: 2714036:G6534_RS06580
uniprot id: A0A7L7KWZ8
names: Function
names: Similarity
messages: Belongs to the UPF0122 family.
messages: Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein.

2714036:G6534 RS02825
gene id: 2714036:G6534_RS02825
uniprot id: A0A7L7KUZ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

2714036:G6534 RS02865
gene id: 2714036:G6534_RS02865
uniprot id: A0A7L7KV08
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mg(2+). Can also accept Mn(2+).

2714036:G6534 RS02980
gene id: 2714036:G6534_RS02980
uniprot id: A0A7L7KV26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

2714036:G6534 RS07900
gene id: 2714036:G6534_RS07900
uniprot id: A0A7L7KYZ3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

2714036:G6534 RS07970
gene id: 2714036:G6534_RS07970
uniprot id: A0A7L7KXQ1
names: Caution
names: Function
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2714036:G6534 RS03875
gene id: 2714036:G6534_RS03875
uniprot id: A0A7L7KWE7
names: Function
names: Similarity
messages: ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.
messages: Belongs to the ParA family. MinD subfamily.

2714036:G6534 RS08625
gene id: 2714036:G6534_RS08625
uniprot id: A0A7L7KY27
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

2714036:G6534 RS05390
gene id: 2714036:G6534_RS05390
uniprot id: A0A7L7KXA4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

2714036:G6534 RS08665
gene id: 2714036:G6534_RS08665
uniprot id: A0A7L7KY12
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2714036:G6534 RS07785
gene id: 2714036:G6534_RS07785
uniprot id: A0A7L7KZW3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

2714036:G6534 RS07895
gene id: 2714036:G6534_RS07895
uniprot id: A0A7L7KXR0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MrnC RNase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc); Rnc processes 30S rRNA into smaller rRNA precursors.

2714036:G6534 RS05565
gene id: 2714036:G6534_RS05565
uniprot id: A0A7L7KWH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

2714036:G6534 RS03270
gene id: 2714036:G6534_RS03270
uniprot id: A0A7L7KV48
names: Similarity
messages: Belongs to the UPF0735 family.

2714036:G6534 RS00410
gene id: 2714036:G6534_RS00410
uniprot id: A0A7L7KTY3
names: Similarity
messages: Belongs to the asparagine synthetase family.

2714036:G6534 RS11070
gene id: 2714036:G6534_RS11070
uniprot id: A0A7L7L0G1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

2714036:G6534 RS03025
gene id: 2714036:G6534_RS03025
uniprot id: A0A7L7KVE8
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

2714036:G6534 RS10800
gene id: 2714036:G6534_RS10800
uniprot id: A0A7L7KZ65
names: Subcellular Location Annotation
messages: Membrane

2714036:G6534 RS05405
gene id: 2714036:G6534_RS05405
uniprot id: A0A7L7KXM1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

2714036:G6534 RS06510
gene id: 2714036:G6534_RS06510
uniprot id: A0A7L7KXU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0154 family.
messages: Membrane

2714036:G6534 RS03235
gene id: 2714036:G6534_RS03235
uniprot id: A0A7L7KXH5
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

2714036:G6534 RS01975
gene id: 2714036:G6534_RS01975
uniprot id: A0A7L7KUK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

2714036:G6534 RS07340
gene id: 2714036:G6534_RS07340
uniprot id: A0A7L7KXD7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

2714036:G6534 RS06480
gene id: 2714036:G6534_RS06480
uniprot id: A0A7L7KWX9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

2714036:G6534 RS07940
gene id: 2714036:G6534_RS07940
uniprot id: A0A7L7KZZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S15 family.
messages: Cytoplasm
messages: Homodimer.
messages: Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline.

2714036:G6534 RS07565
gene id: 2714036:G6534_RS07565
uniprot id: A0A7L7KXF6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

2714036:G6534 RS06565
gene id: 2714036:G6534_RS06565
uniprot id: A0A7L7KWZ2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein S19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein S19.

2714036:G6534 RS10430
gene id: 2714036:G6534_RS10430
uniprot id: A0A7L7KZ31
names: Similarity
messages: Belongs to the ParB family.

2714036:G6534 RS06370
gene id: 2714036:G6534_RS06370
uniprot id: A0A7L7KX04
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

2714036:G6534 RS01300
gene id: 2714036:G6534_RS01300
uniprot id: A0A7L7KVA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Cell membrane
messages: Membrane

2714036:G6534 RS07690
gene id: 2714036:G6534_RS07690
uniprot id: A0A7L7L0A5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

2714036:G6534 RS03005
gene id: 2714036:G6534_RS03005
uniprot id: A0A7L7KV00
names: Subcellular Location Annotation
messages: Membrane

2714036:G6534 RS08095
gene id: 2714036:G6534_RS08095
uniprot id: A0A7L7L023
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

2714036:G6534 RS08125
gene id: 2714036:G6534_RS08125
uniprot id: A0A7L7KXT1
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

2714036:G6534 RS11040
gene id: 2714036:G6534_RS11040
uniprot id: A0A7L7L0P9
names: Subcellular Location Annotation
messages: Membrane

2714036:G6534 RS06420
gene id: 2714036:G6534_RS06420
uniprot id: A0A7L7L0T4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

2714036:G6534 RS01290
gene id: 2714036:G6534_RS01290
uniprot id: A0A7L7KUB4
names: Activity Regulation
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Activated by phosphorylation and inhibited by fructose 1,6-bisphosphate (FBP).
messages: Belongs to the FGGY kinase family.
messages: Homotetramer and homodimer (in equilibrium).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), including enzyme I, and histidine-containing protein (HPr) are required for the phosphorylation, which leads to the activation of the enzyme.

2714036:G6534 RS03250
gene id: 2714036:G6534_RS03250
uniprot id: A0A7L7KV77
names: Similarity
messages: Belongs to the FGGY kinase family.

2714036:G6534 RS09360
gene id: 2714036:G6534_RS09360
uniprot id: A0A7L7KYF1
names: Subcellular Location Annotation
messages: Cytoplasm

2714036:G6534 RS08595
gene id: 2714036:G6534_RS08595
uniprot id: A0A7L7KY44
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2714036:G6534 RS10745
gene id: 2714036:G6534_RS10745
uniprot id: A0A7L7L0C7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

2714036:G6534 RS07135
gene id: 2714036:G6534_RS07135
uniprot id: A0A7L7L020
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

2714036:G6534 RS09405
gene id: 2714036:G6534_RS09405
uniprot id: A0A7L7KYH4
names: Similarity
messages: Belongs to the LDH/MDH superfamily. LDH family.

2714036:G6534 RS08180
gene id: 2714036:G6534_RS08180
uniprot id: A0A7L7KXU3
names: Subcellular Location Annotation
messages: Membrane

2714036:G6534 RS08355
gene id: 2714036:G6534_RS08355
uniprot id: A0A7L7L071
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

2714036:G6534 RS05420
gene id: 2714036:G6534_RS05420
uniprot id: A0A7L7KWJ9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2714036:G6534 RS07990
gene id: 2714036:G6534_RS07990
uniprot id: A0A7L7KXP7
names: Similarity
messages: Belongs to the UPF0177 family.

2714036:G6534 RS03715
gene id: 2714036:G6534_RS03715
uniprot id: A0A7L7KYB6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

2714036:G6534 RS04755
gene id: 2714036:G6534_RS04755
uniprot id: A0A7L7KVY5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.
messages: Cytoplasm
messages: Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity.

2714036:G6534 RS04530
gene id: 2714036:G6534_RS04530
uniprot id: A0A7L7KX59
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

2714036:G6534 RS02330
gene id: 2714036:G6534_RS02330
uniprot id: A0A7L7KW60
names: Subcellular Location Annotation
messages: Membrane

2714036:G6534 RS07760
gene id: 2714036:G6534_RS07760
uniprot id: A0A7L7L194
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

2714036:G6534 RS03610
gene id: 2714036:G6534_RS03610
uniprot id: A0A7L7KVC2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

2714036:G6534 RS01980
gene id: 2714036:G6534_RS01980
uniprot id: A0A7L7KWX8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

2714036:G6534 RS06435
gene id: 2714036:G6534_RS06435
uniprot id: A0A7L7KX12
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

2714036:G6534 RS00355
gene id: 2714036:G6534_RS00355
uniprot id: A0A7L7KV82
names: Subcellular Location Annotation
messages: Membrane

2714036:G6534 RS08640
gene id: 2714036:G6534_RS08640
uniprot id: A0A7L7KY34
names: Similarity
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.

2714036:G6534 RS02830
gene id: 2714036:G6534_RS02830
uniprot id: A0A7L7KUY1
names: Similarity
messages: Belongs to the GSP E family.

2714036:G6534 RS03900
gene id: 2714036:G6534_RS03900
uniprot id: A0A7L7KXU5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsL family.
messages: Cell membrane
messages: Essential cell division protein.
messages: Membrane

2714036:G6534 RS04845
gene id: 2714036:G6534_RS04845
uniprot id: A0A7L7KW06
names: Similarity
messages: Belongs to the LOG family.

2714036:G6534 RS06755
gene id: 2714036:G6534_RS06755
uniprot id: A0A7L7KYF2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

2714036:G6534 RS01050
gene id: 2714036:G6534_RS01050
uniprot id: A0A7L7KUJ2
names: Subcellular Location Annotation
messages: Membrane

2714036:G6534 RS04310
gene id: 2714036:G6534_RS04310
uniprot id: A0A7L7KVP1
names: Cofactor
messages: Binds 1 Mg(2+) ion per trimer.

2714036:G6534 RS10760
gene id: 2714036:G6534_RS10760
uniprot id: A0A7L7KZ95
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

2714036:G6534 RS08275
gene id: 2714036:G6534_RS08275
uniprot id: A0A7L7KYR3
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

2714036:G6534 RS05380
gene id: 2714036:G6534_RS05380
uniprot id: A0A7L7KWD7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

2714036:G6534 RS05210
gene id: 2714036:G6534_RS05210
uniprot id: A0A7L7KYJ6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecU family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation.

2714036:G6534 RS08265
gene id: 2714036:G6534_RS08265
uniprot id: A0A7L7KXT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane

2714036:G6534 RS07750
gene id: 2714036:G6534_RS07750
uniprot id: A0A7L7L0B0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

2714036:G6534 RS02505
gene id: 2714036:G6534_RS02505
uniprot id: A0A7L7KXR9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Membrane

2714036:G6534 RS02395
gene id: 2714036:G6534_RS02395
uniprot id: A0A7L7KXP6
names: Function
names: Similarity
messages: Belongs to the WhiA family.
messages: Involved in cell division and chromosome segregation.

2714036:G6534 RS08295
gene id: 2714036:G6534_RS08295
uniprot id: A0A7L7KXW7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

2714036:G6534 RS08175
gene id: 2714036:G6534_RS08175
uniprot id: A0A7L7KXU2
names: Similarity
messages: Belongs to the glycosyl hydrolase 65 family.

2714036:G6534 RS04095
gene id: 2714036:G6534_RS04095
uniprot id: A0A7L7KVL7
names: Similarity
messages: Belongs to the peptidase S16 family.

2714036:G6534 RS02190
gene id: 2714036:G6534_RS02190
uniprot id: A0A7L7KW29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

2714036:G6534 RS02480
gene id: 2714036:G6534_RS02480
uniprot id: A0A7L7KUU2
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

2714036:G6534 RS10510
gene id: 2714036:G6534_RS10510
uniprot id: A0A7L7L009
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell membrane
messages: Membrane

2714036:G6534 RS08305
gene id: 2714036:G6534_RS08305
uniprot id: A0A7L7KXZ2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

2714036:G6534 RS07160
gene id: 2714036:G6534_RS07160
uniprot id: A0A7L7KXB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arginine deiminase family.
messages: Cytoplasm

2714036:G6534 RS00275
gene id: 2714036:G6534_RS00275
uniprot id: A0A7L7KTR3
names: Similarity
messages: Belongs to the peptidase C69 family.

2714036:G6534 RS04440
gene id: 2714036:G6534_RS04440
uniprot id: A0A7L7KW46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

2714036:G6534 RS01425
gene id: 2714036:G6534_RS01425
uniprot id: A0A7L7KUA6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbsD / FucU family. RbsD subfamily.
messages: Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose.
messages: Cytoplasm
messages: Homodecamer.

2714036:G6534 RS10690
gene id: 2714036:G6534_RS10690
uniprot id: A0A7L7L0C1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OXA1/ALB3/YidC family. Type 2 subfamily.
messages: Cell membrane
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins.

2714036:G6534 RS05530
gene id: 2714036:G6534_RS05530
uniprot id: A0A7L7L0L2
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

2714036:G6534 RS06340
gene id: 2714036:G6534_RS06340
uniprot id: A0A7L7KXS3
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

2714036:G6534 RS08525
gene id: 2714036:G6534_RS08525
uniprot id: A0A7L7KY02
names: Subcellular Location Annotation
messages: Membrane

2714036:G6534 RS10755
gene id: 2714036:G6534_RS10755
uniprot id: A0A7L7L0W3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GdpP/PdeA phosphodiesterase family.
messages: Cell membrane
messages: For phosphodiesterase activity, probably binds 2 Mn(2+) per subunit.
messages: Has phosphodiesterase (PDE) activity against cyclic-di-AMP (c-di-AMP).

2714036:G6534 RS06490
gene id: 2714036:G6534_RS06490
uniprot id: A0A7L7KX23
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

2714036:G6534 RS08985
gene id: 2714036:G6534_RS08985
uniprot id: A0A7L7KZJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

2714036:G6534 RS10910
gene id: 2714036:G6534_RS10910
uniprot id: A0A7L7KZ84
names: Similarity
messages: Belongs to the peptidase C40 family.

2714036:G6534 RS08190
gene id: 2714036:G6534_RS08190
uniprot id: A0A7L7KXU6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

2714036:G6534 RS09100
gene id: 2714036:G6534_RS09100
uniprot id: A0A7L7L0P7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

2714036:G6534 RS08740
gene id: 2714036:G6534_RS08740
uniprot id: A0A7L7KY38
names: Subcellular Location Annotation
messages: Membrane

2714036:G6534 RS06725
gene id: 2714036:G6534_RS06725
uniprot id: A0A7L7KX24
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

2714036:G6534 RS10350
gene id: 2714036:G6534_RS10350
uniprot id: A0A7L7KZW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

2714036:G6534 RS00345
gene id: 2714036:G6534_RS00345
uniprot id: A0A7L7KW15
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

2714036:G6534 RS00255
gene id: 2714036:G6534_RS00255
uniprot id: A0A7L7KTV5
names: Cofactor
names: Similarity
messages: Belongs to the AlaDH/PNT family.
messages: Binds 1 Mg(2+) ion per subunit.

2714036:G6534 RS05300
gene id: 2714036:G6534_RS05300
uniprot id: A0A7L7KXK1
names: Similarity
messages: Belongs to the 4-oxalocrotonate tautomerase family.

2714036:G6534 RS03825
gene id: 2714036:G6534_RS03825
uniprot id: A0A7L7KWD4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

2714036:G6534 RS02280
gene id: 2714036:G6534_RS02280
uniprot id: A0A7L7KVR3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

2714036:G6534 RS06770
gene id: 2714036:G6534_RS06770
uniprot id: A0A7L7KXZ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

2714036:G6534 RS07010
gene id: 2714036:G6534_RS07010
uniprot id: A0A7L7KZE9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
messages: Single-chain monomer with multiple functions.

2714036:G6534 RS02415
gene id: 2714036:G6534_RS02415
uniprot id: A0A7L7KW55
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

2714036:G6534 RS05285
gene id: 2714036:G6534_RS05285
uniprot id: A0A7L7KX85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Cell membrane
messages: Membrane

2714036:G6534 RS08120
gene id: 2714036:G6534_RS08120
uniprot id: A0A7L7KYM8
names: Function
names: Similarity
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids threonine, isoleucine and methionine.

2714036:G6534 RS03765
gene id: 2714036:G6534_RS03765
uniprot id: A0A7L7KVG1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

2714036:G6534 RS08330
gene id: 2714036:G6534_RS08330
uniprot id: A0A7L7KYS4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

2714036:G6534 RS05425
gene id: 2714036:G6534_RS05425
uniprot id: A0A7L7KXS5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

2714036:G6534 RS07090
gene id: 2714036:G6534_RS07090
uniprot id: A0A7L7KX93
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PrsA family.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins.

2714036:G6534 RS05255
gene id: 2714036:G6534_RS05255
uniprot id: A0A7L7KWB6
names: Similarity
messages: Belongs to the diphosphomevalonate decarboxylase family.

2714036:G6534 RS05370
gene id: 2714036:G6534_RS05370
uniprot id: A0A7L7KWI8
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

2714036:G6534 RS08885
gene id: 2714036:G6534_RS08885
uniprot id: A0A7L7L0M8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

2714036:G6534 RS07965
gene id: 2714036:G6534_RS07965
uniprot id: A0A7L7KYJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GRP transporter (TC 2.A.7.5) family.
messages: Cell membrane
messages: Membrane

2714036:G6534 RS10610
gene id: 2714036:G6534_RS10610
uniprot id: A0A7L7KZ41
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
messages: Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2714036:G6534 RS06825
gene id: 2714036:G6534_RS06825
uniprot id: A0A7L7KZW2
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

2714036:G6534 RS08410
gene id: 2714036:G6534_RS08410
uniprot id: A0A7L7L080
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

2714036:G6534 RS01105
gene id: 2714036:G6534_RS01105
uniprot id: A0A7L7KWA4
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.

2714036:G6534 RS01670
gene id: 2714036:G6534_RS01670
uniprot id: A0A7L7KUU7
names: Similarity
messages: Belongs to the UDPGP type 2 family.

2714036:G6534 RS06835
gene id: 2714036:G6534_RS06835
uniprot id: A0A7L7KX45
names: Subcellular Location Annotation
messages: Membrane

2714036:G6534 RS01065
gene id: 2714036:G6534_RS01065
uniprot id: A0A7L7KU80
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

2714036:G6534 RS08340
gene id: 2714036:G6534_RS08340
uniprot id: A0A7L7KXX0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

2714036:G6534 RS09630
gene id: 2714036:G6534_RS09630
uniprot id: A0A7L7L0L5
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

2714036:G6534 RS04780
gene id: 2714036:G6534_RS04780
uniprot id: A0A7L7KVZ9
names: Similarity
messages: Belongs to the peptidase T1B family. HslV subfamily.

2714036:G6534 RS03995
gene id: 2714036:G6534_RS03995
uniprot id: A0A7L7KWV0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm

2714036:G6534 RS01640
gene id: 2714036:G6534_RS01640
uniprot id: A0A7L7KUE0
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

2714036:G6534 RS05870
gene id: 2714036:G6534_RS05870
uniprot id: A0A7L7KWM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

2714036:G6534 RS03845
gene id: 2714036:G6534_RS03845
uniprot id: A0A7L7KVF2
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

2714036:G6534 RS02205
gene id: 2714036:G6534_RS02205
uniprot id: A0A7L7KV36
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Homohexamer. Forms a ring that surrounds DNA.
messages: Membrane

2714036:G6534 RS08165
gene id: 2714036:G6534_RS08165
uniprot id: A0A7L7L0G0
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.

2714036:G6534 RS01525
gene id: 2714036:G6534_RS01525
uniprot id: A0A7L7KX92
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane.

2714036:G6534 RS09215
gene id: 2714036:G6534_RS09215
uniprot id: A0A7L7KZ81
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

2714036:G6534 RS07575
gene id: 2714036:G6534_RS07575
uniprot id: A0A7L7L0M2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvB family.
messages: Forms a complex with RuvA.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.

2714036:G6534 RS04320
gene id: 2714036:G6534_RS04320
uniprot id: A0A7L7KVQ2
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

2714036:G6534 RS07505
gene id: 2714036:G6534_RS07505
uniprot id: A0A7L7KXE7
names: Similarity
messages: Belongs to the thioredoxin family.

2714036:G6534 RS04645
gene id: 2714036:G6534_RS04645
uniprot id: A0A7L7KX76
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic riboflavin transporter (P-RFT) (TC 2.A.87) family.
messages: Cell membrane
messages: Membrane
messages: Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex.

2714036:G6534 RS07190
gene id: 2714036:G6534_RS07190
uniprot id: A0A7L7KX94
names: Function
names: Similarity
messages: Belongs to the IMPDH/GMPR family. GuaC type 2 subfamily.
messages: Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.

2714036:G6534 RS08395
gene id: 2714036:G6534_RS08395
uniprot id: A0A7L7KXY0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

2714036:G6534 RS08715
gene id: 2714036:G6534_RS08715
uniprot id: A0A7L7KZE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. EmrB family.
messages: Cell membrane
messages: Membrane

2714036:G6534 RS09150
gene id: 2714036:G6534_RS09150
uniprot id: A0A7L7KZP2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane

2714036:G6534 RS05340
gene id: 2714036:G6534_RS05340
uniprot id: A0A7L7KX95
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

2714036:G6534 RS06390
gene id: 2714036:G6534_RS06390
uniprot id: A0A7L7KZP5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

2714036:G6534 RS06595
gene id: 2714036:G6534_RS06595
uniprot id: A0A7L7KYC0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

2714036:G6534 RS06515
gene id: 2714036:G6534_RS06515
uniprot id: A0A7L7KWY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0291 family.
messages: Cytoplasm

2714036:G6534 RS03835
gene id: 2714036:G6534_RS03835
uniprot id: A0A7L7KVE9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThiI family.
messages: Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
messages: Cytoplasm

2714036:G6534 RS00615
gene id: 2714036:G6534_RS00615
uniprot id: A0A7L7KUB9
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.

2714036:G6534 RS07680
gene id: 2714036:G6534_RS07680
uniprot id: A0A7L7KXH7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

2714036:G6534 RS11125
gene id: 2714036:G6534_RS11125
uniprot id: A0A7L7L0G6
names: Cofactor
messages: Binds 1 Mg(2+) ion per trimer.

2714036:G6534 RS08025
gene id: 2714036:G6534_RS08025
uniprot id: A0A7L7KXR1
names: Subcellular Location Annotation
messages: Membrane

2714036:G6534 RS02380
gene id: 2714036:G6534_RS02380
uniprot id: A0A7L7KW64
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

2714036:G6534 RS06735
gene id: 2714036:G6534_RS06735
uniprot id: A0A7L7KY99
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

2714036:G6534 RS07935
gene id: 2714036:G6534_RS07935
uniprot id: A0A7L7KXN8
names: Similarity
messages: Belongs to the peptidase C1 family.

2714036:G6534 RS03920
gene id: 2714036:G6534_RS03920
uniprot id: A0A7L7L024
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2714036:G6534 RS01170
gene id: 2714036:G6534_RS01170
uniprot id: A0A7L7KVM5
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

2714036:G6534 RS07415
gene id: 2714036:G6534_RS07415
uniprot id: A0A7L7L0T7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

2714036:G6534 RS01430
gene id: 2714036:G6534_RS01430
uniprot id: A0A7L7KUB0
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

2714036:G6534 RS06485
gene id: 2714036:G6534_RS06485
uniprot id: A0A7L7KZ47
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

2714036:G6534 RS05715
gene id: 2714036:G6534_RS05715
uniprot id: A0A7L7KWJ5
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

2714036:G6534 RS09120
gene id: 2714036:G6534_RS09120
uniprot id: A0A7L7KYA8
names: Similarity
messages: Belongs to the helicase family. RAD3/XPD subfamily.

2714036:G6534 RS07580
gene id: 2714036:G6534_RS07580
uniprot id: A0A7L7KYC6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

2714036:G6534 RS08150
gene id: 2714036:G6534_RS08150
uniprot id: A0A7L7KXW1
names: Subcellular Location Annotation
messages: Membrane

2714036:G6534 RS05670
gene id: 2714036:G6534_RS05670
uniprot id: A0A7L7KXS2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

2714036:G6534 RS00140
gene id: 2714036:G6534_RS00140
uniprot id: A0A7L7KTU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein SsuA/TauA family.
messages: Periplasm

2714036:G6534 RS02250
gene id: 2714036:G6534_RS02250
uniprot id: A0A7L7L0R2
names: Subcellular Location Annotation
messages: Membrane

2714036:G6534 RS02760
gene id: 2714036:G6534_RS02760
uniprot id: A0A7L7KUZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

2714036:G6534 RS06960
gene id: 2714036:G6534_RS06960
uniprot id: A0A7L7KXA9
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

2714036:G6534 RS09370
gene id: 2714036:G6534_RS09370
uniprot id: A0A7L7KZB5
names: Similarity
messages: Belongs to the RutC family.

2714036:G6534 RS03730
gene id: 2714036:G6534_RS03730
uniprot id: A0A7L7KVE7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

2714036:G6534 RS03200
gene id: 2714036:G6534_RS03200
uniprot id: A0A7L7KV65
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

2714036:G6534 RS02535
gene id: 2714036:G6534_RS02535
uniprot id: A0A7L7KX78
names: Subcellular Location Annotation
messages: cell wall

2714036:G6534 RS07360
gene id: 2714036:G6534_RS07360
uniprot id: A0A7L7KXH3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

2714036:G6534 RS08335
gene id: 2714036:G6534_RS08335
uniprot id: A0A7L7KXX3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

2714036:G6534 RS07280
gene id: 2714036:G6534_RS07280
uniprot id: A0A7L7KXC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. EmrB family.
messages: Cell membrane
messages: Membrane

2714036:G6534 RS07725
gene id: 2714036:G6534_RS07725
uniprot id: A0A7L7KZV4
names: Similarity
names: Subunit
messages: Belongs to the UPF0210 family.
messages: Homodimer.

2714036:G6534 RS11700
gene id: 2714036:G6534_RS11700
uniprot id: A0A7L7KZL2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. AsnA subfamily.
messages: Cytoplasm

2714036:G6534 RS00840
gene id: 2714036:G6534_RS00840
uniprot id: A0A7L7KUF6
names: Similarity
messages: Belongs to the HicA mRNA interferase family.

2714036:G6534 RS01945
gene id: 2714036:G6534_RS01945
uniprot id: A0A7L7KUL8
names: Similarity
messages: Belongs to the PHP hydrolase family. HisK subfamily.

2714036:G6534 RS02085
gene id: 2714036:G6534_RS02085
uniprot id: A0A7L7KUL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

2714036:G6534 RS06860
gene id: 2714036:G6534_RS06860
uniprot id: A0A7L7KX90
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

2714036:G6534 RS08445
gene id: 2714036:G6534_RS08445
uniprot id: A0A7L7KXY7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

2714036:G6534 RS11235
gene id: 2714036:G6534_RS11235
uniprot id: A0A7L7KZE4
names: Similarity
messages: Belongs to the LacAB/RpiB family.

2714036:G6534 RS07495
gene id: 2714036:G6534_RS07495
uniprot id: A0A7L7KXJ2
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

2714036:G6534 RS08450
gene id: 2714036:G6534_RS08450
uniprot id: A0A7L7L0N0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

2714036:G6534 RS07870
gene id: 2714036:G6534_RS07870
uniprot id: A0A7L7KXN0
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

2714036:G6534 RS03865
gene id: 2714036:G6534_RS03865
uniprot id: A0A7L7KVH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Membrane

2714036:G6534 RS05165
gene id: 2714036:G6534_RS05165
uniprot id: A0A7L7KZ50
names: Similarity
messages: Belongs to the formate--tetrahydrofolate ligase family.

2714036:G6534 RS08290
gene id: 2714036:G6534_RS08290
uniprot id: A0A7L7KZ20
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

2714036:G6534 RS08050
gene id: 2714036:G6534_RS08050
uniprot id: A0A7L7KXT9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane

2714036:G6534 RS06335
gene id: 2714036:G6534_RS06335
uniprot id: A0A7L7KZP1
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

2714036:G6534 RS04185
gene id: 2714036:G6534_RS04185
uniprot id: A0A7L7KVP0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2714036:G6534 RS08280
gene id: 2714036:G6534_RS08280
uniprot id: A0A7L7KXW3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

2714036:G6534 RS04570
gene id: 2714036:G6534_RS04570
uniprot id: A0A7L7KVV8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

2714036:G6534 RS03895
gene id: 2714036:G6534_RS03895
uniprot id: A0A7L7KVG2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

2714036:G6534 RS07345
gene id: 2714036:G6534_RS07345
uniprot id: A0A7L7KYK6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

2714036:G6534 RS06720
gene id: 2714036:G6534_RS06720
uniprot id: A0A7L7KXZ0
names: Similarity
messages: Belongs to the TlyA family.

2714036:G6534 RS03745
gene id: 2714036:G6534_RS03745
uniprot id: A0A7L7KVD3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

2714036:G6534 RS04560
gene id: 2714036:G6534_RS04560
uniprot id: A0A7L7KYT9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

2714036:G6534 RS04090
gene id: 2714036:G6534_RS04090
uniprot id: A0A7L7KWJ4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

2714036:G6534 RS04760
gene id: 2714036:G6534_RS04760
uniprot id: A0A7L7KYB4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

2714036:G6534 RS10630
gene id: 2714036:G6534_RS10630
uniprot id: A0A7L7KZ40
names: Similarity
messages: Belongs to the LacAB/RpiB family.

2714036:G6534 RS03760
gene id: 2714036:G6534_RS03760
uniprot id: A0A7L7KWT9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2714036:G6534 RS02360
gene id: 2714036:G6534_RS02360
uniprot id: A0A7L7KW50
names: Similarity
messages: Belongs to the phosphohexose mutase family.

2714036:G6534 RS04155
gene id: 2714036:G6534_RS04155
uniprot id: A0A7L7KWY4
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

2714036:G6534 RS07440
gene id: 2714036:G6534_RS07440
uniprot id: A0A7L7KZN2
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

2714036:G6534 RS02275
gene id: 2714036:G6534_RS02275
uniprot id: A0A7L7KXM9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

2714036:G6534 RS02170
gene id: 2714036:G6534_RS02170
uniprot id: A0A7L7KVP6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

2714036:G6534 RS02565
gene id: 2714036:G6534_RS02565
uniprot id: A0A7L7KVW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LTA synthase family.
messages: Cell membrane
messages: Membrane

2714036:G6534 RS08325
gene id: 2714036:G6534_RS08325
uniprot id: A0A7L7L0H5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

2714036:G6534 RS08010
gene id: 2714036:G6534_RS08010
uniprot id: A0A7L7KXN7
names: Subcellular Location Annotation
messages: Membrane

2714036:G6534 RS05850
gene id: 2714036:G6534_RS05850
uniprot id: A0A7L7KWL3
names: Similarity
messages: Belongs to the glycosyl hydrolase 65 family.

2714036:G6534 RS03240
gene id: 2714036:G6534_RS03240
uniprot id: A0A7L7KVI8
names: Similarity
messages: Belongs to the glycosyl hydrolase 65 family.

2714036:G6534 RS00120
gene id: 2714036:G6534_RS00120
uniprot id: A0A7L7KTP2
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2714036:G6534 RS03935
gene id: 2714036:G6534_RS03935
uniprot id: A0A7L7KVI7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

2714036:G6534 RS03150
gene id: 2714036:G6534_RS03150
uniprot id: A0A7L7L1H9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

2714036:G6534 RS08895
gene id: 2714036:G6534_RS08895
uniprot id: A0A7L7KY78
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

2714036:G6534 RS08535
gene id: 2714036:G6534_RS08535
uniprot id: A0A7L7KY08
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

2714036:G6534 RS06625
gene id: 2714036:G6534_RS06625
uniprot id: A0A7L7KX02
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

2714036:G6534 RS07520
gene id: 2714036:G6534_RS07520
uniprot id: A0A7L7KXG4
names: Similarity
messages: Belongs to the UPF0473 family.

2714036:G6534 RS09330
gene id: 2714036:G6534_RS09330
uniprot id: A0A7L7KYE7
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

2714036:G6534 RS05240
gene id: 2714036:G6534_RS05240
uniprot id: A0A7L7KWB0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. AddA subfamily.
messages: Heterodimer of AddA and AddB/RexB.
messages: The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation; this subunit has the helicase and 3' -> 5' nuclease activities.

2714036:G6534 RS05820
gene id: 2714036:G6534_RS05820
uniprot id: A0A7L7KWL2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

2714036:G6534 RS04165
gene id: 2714036:G6534_RS04165
uniprot id: A0A7L7KXZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

2714036:G6534 RS08650
gene id: 2714036:G6534_RS08650
uniprot id: A0A7L7KY56
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

2714036:G6534 RS07310
gene id: 2714036:G6534_RS07310
uniprot id: A0A7L7KXG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

2714036:G6534 RS07590
gene id: 2714036:G6534_RS07590
uniprot id: A0A7L7KXH6
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

2714036:G6534 RS03985
gene id: 2714036:G6534_RS03985
uniprot id: A0A7L7KVJ6
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.

2714036:G6534 RS00115
gene id: 2714036:G6534_RS00115
uniprot id: A0A7L7KV30
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

2714036:G6534 RS00630
gene id: 2714036:G6534_RS00630
uniprot id: A0A7L7KWU7
names: Subcellular Location Annotation
messages: Membrane

2714036:G6534 RS08425
gene id: 2714036:G6534_RS08425
uniprot id: A0A7L7KXW5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

2714036:G6534 RS00990
gene id: 2714036:G6534_RS00990
uniprot id: A0A7L7KUI4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NRAMP family.
messages: Cell membrane
messages: H(+)-stimulated, divalent metal cation uptake system.

2714036:G6534 RS06425
gene id: 2714036:G6534_RS06425
uniprot id: A0A7L7KWW8
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by GTP. Inhibited by UTP.
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2714036:G6534 RS00150
gene id: 2714036:G6534_RS00150
uniprot id: A0A7L7KUQ5
names: Similarity
messages: Belongs to the SecB family.

2714036:G6534 RS02895
gene id: 2714036:G6534_RS02895
uniprot id: A0A7L7KWA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

2714036:G6534 RS02110
gene id: 2714036:G6534_RS02110
uniprot id: A0A7L7KXJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family.
messages: Cell membrane

2714036:G6534 RS03615
gene id: 2714036:G6534_RS03615
uniprot id: A0A7L7KVA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

2714036:G6534 RS06475
gene id: 2714036:G6534_RS06475
uniprot id: A0A7L7KY54
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2714036:G6534 RS05735
gene id: 2714036:G6534_RS05735
uniprot id: A0A7L7KWQ1
names: Subcellular Location Annotation
messages: Membrane

2714036:G6534 RS11675
gene id: 2714036:G6534_RS11675
uniprot id: A0A7L7L0P0
names: Similarity
messages: Belongs to the glycosyl hydrolase.

2714036:G6534 RS02245
gene id: 2714036:G6534_RS02245
uniprot id: A0A7L7KUP5
names: Function
names: Similarity
messages: Belongs to the RNase Y family.
messages: Endoribonuclease that initiates mRNA decay.

2714036:G6534 RS06995
gene id: 2714036:G6534_RS06995
uniprot id: A0A7L7KX77
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

2714036:G6534 RS09355
gene id: 2714036:G6534_RS09355
uniprot id: A0A7L7KZR9
names: Subcellular Location Annotation
messages: Membrane

2714036:G6534 RS07115
gene id: 2714036:G6534_RS07115
uniprot id: A0A7L7KZH3
names: Similarity
messages: Belongs to the UPF0342 family.

2714036:G6534 RS04020
gene id: 2714036:G6534_RS04020
uniprot id: A0A7L7KVL2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

2714036:G6534 RS04125
gene id: 2714036:G6534_RS04125
uniprot id: A0A7L7KX16
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2714036:G6534 RS04830
gene id: 2714036:G6534_RS04830
uniprot id: A0A7L7KW11
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2714036:G6534 RS02485
gene id: 2714036:G6534_RS02485
uniprot id: A0A7L7KX65
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

2714036:G6534 RS07555
gene id: 2714036:G6534_RS07555
uniprot id: A0A7L7KYT5
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2714036:G6534 RS01355
gene id: 2714036:G6534_RS01355
uniprot id: A0A7L7KX61
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
messages: Homodimer.

2714036:G6534 RS00010
gene id: 2714036:G6534_RS00010
uniprot id: A0A7L7KTS5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2714036:G6534 RS08635
gene id: 2714036:G6534_RS08635
uniprot id: A0A7L7KZ87
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2714036:G6534 RS06810
gene id: 2714036:G6534_RS06810
uniprot id: A0A7L7KX81
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

2714036:G6534 RS02135
gene id: 2714036:G6534_RS02135
uniprot id: A0A7L7L132
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MecA family.
messages: Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis.
messages: Homodimer.
messages: The N-terminal domain probably binds unfolded/aggregated proteins; the C-terminal domain interacts with ClpC.

2714036:G6534 RS08375
gene id: 2714036:G6534_RS08375
uniprot id: A0A7L7L0I0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

2714036:G6534 RS09395
gene id: 2714036:G6534_RS09395
uniprot id: A0A7L7L0T1
names: Similarity
messages: Belongs to the LDH/MDH superfamily. LDH family.

2714036:G6534 RS02490
gene id: 2714036:G6534_RS02490
uniprot id: A0A7L7KV83
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

2714036:G6534 RS08085
gene id: 2714036:G6534_RS08085
uniprot id: A0A7L7KYX9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily.
messages: Homodimer.
messages: Involved in phosphonate degradation.

2714036:G6534 RS04520
gene id: 2714036:G6534_RS04520
uniprot id: A0A7L7KZW6
names: Subcellular Location Annotation
messages: Membrane

2714036:G6534 RS08560
gene id: 2714036:G6534_RS08560
uniprot id: A0A7L7L0J5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Belongs to the P-Pant transferase superfamily. Gsp/Sfp/HetI/AcpT family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

2714036:G6534 RS08420
gene id: 2714036:G6534_RS08420
uniprot id: A0A7L7KZ86
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

2714036:G6534 RS00290
gene id: 2714036:G6534_RS00290
uniprot id: A0A7L7KTR9
names: Similarity
messages: Belongs to the peptidase C69 family.

2714036:G6534 RS08870
gene id: 2714036:G6534_RS08870
uniprot id: A0A7L7KY97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

2714036:G6534 RS06555
gene id: 2714036:G6534_RS06555
uniprot id: A0A7L7KZR5
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

2714036:G6534 RS07000
gene id: 2714036:G6534_RS07000
uniprot id: A0A7L7KYE9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

2714036:G6534 RS05070
gene id: 2714036:G6534_RS05070
uniprot id: A0A7L7L170
names: Similarity
messages: Belongs to the YoeB family.

2714036:G6534 RS08550
gene id: 2714036:G6534_RS08550
uniprot id: A0A7L7KZA9
names: Cofactor
names: Similarity
messages: Belongs to the AlaDH/PNT family.
messages: Binds 1 Mg(2+) ion per subunit.

2714036:G6534 RS05470
gene id: 2714036:G6534_RS05470
uniprot id: A0A7L7KWK9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

2714036:G6534 RS05220
gene id: 2714036:G6534_RS05220
uniprot id: A0A7L7KXN6
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2714036:G6534 RS03365
gene id: 2714036:G6534_RS03365
uniprot id: A0A7L7KWL4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

2714036:G6534 RS10770
gene id: 2714036:G6534_RS10770
uniprot id: A0A7L7KZ68
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

2714036:G6534 RS02260
gene id: 2714036:G6534_RS02260
uniprot id: A0A7L7KV45
names: Similarity
messages: Belongs to the IMPACT family.

2714036:G6534 RS11930
gene id: 2714036:G6534_RS11930
uniprot id: A0A7L7L1E2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

2714036:G6534 RS10250
gene id: 2714036:G6534_RS10250
uniprot id: A0A7L7KZU1
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

2714036:G6534 RS09410
gene id: 2714036:G6534_RS09410
uniprot id: A0A7L7L0J7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

2714036:G6534 RS04510
gene id: 2714036:G6534_RS04510
uniprot id: A0A7L7KWT2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

2714036:G6534 RS00960
gene id: 2714036:G6534_RS00960
uniprot id: A0A7L7KV44
names: Similarity
messages: Belongs to the alpha-acetolactate decarboxylase family.

2714036:G6534 RS04700
gene id: 2714036:G6534_RS04700
uniprot id: A0A7L7KVX5
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A single active site specifically recognizes both ATP and CTP and is responsible for their addition.
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 3 subfamily.
messages: Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate.
messages: Homodimer.

2714036:G6534 RS10955
gene id: 2714036:G6534_RS10955
uniprot id: A0A7L7KZH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

2714036:G6534 RS07945
gene id: 2714036:G6534_RS07945
uniprot id: A0A7L7KXS0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAK/KUP transporter (TC 2.A.72) family.
messages: Cell membrane
messages: Membrane
messages: Transport of potassium into the cell.

2714036:G6534 RS08500
gene id: 2714036:G6534_RS08500
uniprot id: A0A7L7KZ96
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm
messages: Purine salvage pathway enzyme that catalyzes the transfer of the ribosyl-5-phosphate group from 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to the N9 position of the 6-oxopurines hypoxanthine and guanine to form the corresponding ribonucleotides IMP (inosine 5'-monophosphate) and GMP (guanosine 5'-monophosphate), with the release of PPi.

2714036:G6534 RS00490
gene id: 2714036:G6534_RS00490
uniprot id: A0A7L7KTV2
names: Similarity
messages: Belongs to the EamA transporter family.

2714036:G6534 RS01015
gene id: 2714036:G6534_RS01015
uniprot id: A0A7L7KX05
names: Similarity
messages: Belongs to the polypeptide deformylase family.

2714036:G6534 RS02230
gene id: 2714036:G6534_RS02230
uniprot id: A0A7L7KUQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane
messages: This protein catalyzes the committed step to the synthesis of the acidic phospholipids.

2714036:G6534 RS02030
gene id: 2714036:G6534_RS02030
uniprot id: A0A7L7KUL3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HPr family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The phosphoryl group from phosphoenolpyruvate (PEP) is transferred to the phosphoryl carrier protein HPr by enzyme I. Phospho-HPr then transfers it to the PTS EIIA domain.
messages: P-Ser-HPr interacts with the catabolite control protein A (CcpA), forming a complex that binds to DNA at the catabolite response elements cre, operator sites preceding a large number of catabolite-regulated genes. Thus, P-Ser-HPr is a corepressor in carbon catabolite repression (CCR), a mechanism that allows bacteria to coordinate and optimize the utilization of available carbon sources. P-Ser-HPr also plays a role in inducer exclusion, in which it probably interacts with several non-PTS permeases and inhibits their transport activity.

2714036:G6534 RS05690
gene id: 2714036:G6534_RS05690
uniprot id: A0A7L7KXW6
names: Similarity
messages: Belongs to the polysaccharide lyase 8 family.

2714036:G6534 RS07425
gene id: 2714036:G6534_RS07425
uniprot id: A0A7L7KXE9
names: Function
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. NagD family.
messages: Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro.

2714036:G6534 RS00330
gene id: 2714036:G6534_RS00330
uniprot id: A0A7L7KTS9
names: Similarity
messages: Belongs to the XFP family.

2714036:G6534 RS04585
gene id: 2714036:G6534_RS04585
uniprot id: A0A7L7KVV3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-C family. DnaE subfamily.
messages: Cytoplasm
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The alpha chain is the DNA polymerase.

2714036:G6534 RS09900
gene id: 2714036:G6534_RS09900
uniprot id: A0A7L7KYQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

2714036:G6534 RS01680
gene id: 2714036:G6534_RS01680
uniprot id: A0A7L7KUI2
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

2714036:G6534 RS07245
gene id: 2714036:G6534_RS07245
uniprot id: A0A7L7KYP1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Homotetramer.

2714036:G6534 RS04180
gene id: 2714036:G6534_RS04180
uniprot id: A0A7L7KX27
names: Function
names: Similarity
names: Subunit
messages: Belongs to the OMP decarboxylase family. Type 1 subfamily.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
messages: Homodimer.

2714036:G6534 RS02375
gene id: 2714036:G6534_RS02375
uniprot id: A0A7L7KV64
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

2714036:G6534 RS06970
gene id: 2714036:G6534_RS06970
uniprot id: A0A7L7L055
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-3 family.
messages: Cytoplasm
messages: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
messages: Monomer.

2714036:G6534 RS02750
gene id: 2714036:G6534_RS02750
uniprot id: A0A7L7KVA0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

2714036:G6534 RS01460
gene id: 2714036:G6534_RS01460
uniprot id: A0A7L7KUE6
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

2714036:G6534 RS02445
gene id: 2714036:G6534_RS02445
uniprot id: A0A7L7KUW2
names: PTM
names: Subcellular Location Annotation
messages: Covalently binds the prosthetic group of malonate decarboxylase.
messages: Cytoplasm

2714036:G6534 RS00575
gene id: 2714036:G6534_RS00575
uniprot id: A0A7L7KU07
names: Similarity
messages: Belongs to the thioester dehydratase family. FabZ subfamily.

2714036:G6534 RS08940
gene id: 2714036:G6534_RS08940
uniprot id: A0A7L7KY64
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

2714036:G6534 RS04205
gene id: 2714036:G6534_RS04205
uniprot id: A0A7L7KVM4
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.
messages: Belongs to the thioester dehydratase family. FabZ subfamily.

2714036:G6534 RS05400
gene id: 2714036:G6534_RS05400
uniprot id: A0A7L7KWD6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AP endonuclease 2 family.
messages: Binds 3 Zn(2+) ions.
messages: Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.

2714036:G6534 RS02305
gene id: 2714036:G6534_RS02305
uniprot id: A0A7L7KW43
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

2714036:G6534 RS05020
gene id: 2714036:G6534_RS05020
uniprot id: A0A7L7KXF5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

2714036:G6534 RS08495
gene id: 2714036:G6534_RS08495
uniprot id: A0A7L7KY23
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

2714036:G6534 RS01990
gene id: 2714036:G6534_RS01990
uniprot id: A0A7L7KV01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA-PH family.
messages: Cytoplasm

2714036:G6534 RS08415
gene id: 2714036:G6534_RS08415
uniprot id: A0A7L7KY13
names: Similarity
messages: Belongs to the UPF0177 family.

2714036:G6534 RS07355
gene id: 2714036:G6534_RS07355
uniprot id: A0A7L7KZL5
names: Function
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family. DapH subfamily.
messages: Catalyzes the transfer of an acetyl group from acetyl-CoA to tetrahydrodipicolinate.

2714036:G6534 RS06890
gene id: 2714036:G6534_RS06890
uniprot id: A0A7L7KX57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OXA1/ALB3/YidC family.
messages: Membrane

2714036:G6534 RS10735
gene id: 2714036:G6534_RS10735
uniprot id: A0A7L7KZC8
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

2714036:G6534 RS04555
gene id: 2714036:G6534_RS04555
uniprot id: A0A7L7KVW0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase Z family.
messages: Binds 2 Zn(2+) ions.
messages: Homodimer.
messages: Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.

2714036:G6534 RS04925
gene id: 2714036:G6534_RS04925
uniprot id: A0A7L7KXI5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2714036:G6534 RS04050
gene id: 2714036:G6534_RS04050
uniprot id: A0A7L7KWW3
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

2714036:G6534 RS00985
gene id: 2714036:G6534_RS00985
uniprot id: A0A7L7KW86
names: Similarity
messages: Belongs to the universal stress protein A family.

2714036:G6534 RS03775
gene id: 2714036:G6534_RS03775
uniprot id: A0A7L7KWC5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

2714036:G6534 RS06300
gene id: 2714036:G6534_RS06300
uniprot id: A0A7L7KWU0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

2714036:G6534 RS01850
gene id: 2714036:G6534_RS01850
uniprot id: A0A7L7KXF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

2714036:G6534 RS11285
gene id: 2714036:G6534_RS11285
uniprot id: A0A7L7KZF5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S33 family.
messages: Cell envelope
messages: Releases the N-terminal proline from various substrates.

2714036:G6534 RS09060
gene id: 2714036:G6534_RS09060
uniprot id: A0A7L7KYA5
names: Subcellular Location Annotation
messages: Membrane

2714036:G6534 RS02525
gene id: 2714036:G6534_RS02525
uniprot id: A0A7L7KW65
names: Similarity
messages: Belongs to the peptidase S66 family.

2714036:G6534 RS10215
gene id: 2714036:G6534_RS10215
uniprot id: A0A7L7KYW5
names: Subcellular Location Annotation
messages: Membrane

2714036:G6534 RS02775
gene id: 2714036:G6534_RS02775
uniprot id: A0A7L7KUY5
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

2714036:G6534 RS07825
gene id: 2714036:G6534_RS07825
uniprot id: A0A7L7KYS5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

2714036:G6534 RS04015
gene id: 2714036:G6534_RS04015
uniprot id: A0A7L7KWZ9
names: Similarity
messages: Belongs to the diacylglycerol/lipid kinase family.

2714036:G6534 RS00485
gene id: 2714036:G6534_RS00485
uniprot id: A0A7L7KUV5
names: Similarity
messages: Belongs to the bacterial solute-binding protein 1 family.

2714036:G6534 RS07745
gene id: 2714036:G6534_RS07745
uniprot id: A0A7L7KZY6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.