269799:GMET RS09965
gene id: 269799:GMET_RS09965
uniprot id: Q39U72
names: Similarity
messages: Belongs to the Nth/MutY family.

269799:GMET RS04035
gene id: 269799:GMET_RS04035
uniprot id: Q39XH6
names: Subcellular Location Annotation
messages: Membrane

269799:GMET RS14750
gene id: 269799:GMET_RS14750
uniprot id: Q39RG8
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

269799:GMET RS11920
gene id: 269799:GMET_RS11920
uniprot id: Q39T34
names: Similarity
messages: Belongs to the peptidase C40 family.

269799:GMET RS10725
gene id: 269799:GMET_RS10725
uniprot id: Q39TR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetokinase family.
messages: Cytoplasm

269799:GMET RS16525
gene id: 269799:GMET_RS16525
uniprot id: Q39QG4
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

269799:GMET RS16975
gene id: 269799:GMET_RS16975
uniprot id: Q39Q75
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

269799:GMET RS11110
gene id: 269799:GMET_RS11110
uniprot id: Q39TJ1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

269799:GMET RS14385
gene id: 269799:GMET_RS14385
uniprot id: Q39RP0
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

269799:GMET RS17120
gene id: 269799:GMET_RS17120
uniprot id: Q39Q47
names: Function
messages: Translation factor necessary for the incorporation of selenocysteine into proteins. It probably replaces EF-Tu for the insertion of selenocysteine directed by the UGA codon. SelB binds GTP and GDP.

269799:GMET RS04760
gene id: 269799:GMET_RS04760
uniprot id: Q39X31
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell inner membrane
messages: Cytoplasm
messages: May bind 1 zinc ion per subunit.
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

269799:GMET RS11885
gene id: 269799:GMET_RS11885
uniprot id: Q39T41
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3.A.1.125) family.
messages: Cell inner membrane
messages: Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.
messages: The complex is composed of two ATP-binding proteins (LolD) and two transmembrane proteins (LolC and LolE).

269799:GMET RS12785
gene id: 269799:GMET_RS12785
uniprot id: Q39SK9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase E/G family. RNase E subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per homotetramer.
messages: Cell inner membrane
messages: Cytoplasm
messages: Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs.
messages: Homotetramer formed by a dimer of dimers.

269799:GMET RS16210
gene id: 269799:GMET_RS16210
uniprot id: Q39QM6
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

269799:GMET RS14915
gene id: 269799:GMET_RS14915
uniprot id: Q39RD5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
messages: Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
messages: Homodimer.

269799:GMET RS10815
gene id: 269799:GMET_RS10815
uniprot id: Q39TP9
names: Subcellular Location Annotation
messages: Membrane

269799:GMET RS08590
gene id: 269799:GMET_RS08590
uniprot id: Q39UY6
names: Subcellular Location Annotation
messages: Cell inner membrane

269799:GMET RS16585
gene id: 269799:GMET_RS16585
uniprot id: Q39QF2
names: Similarity
messages: Belongs to the Nudix hydrolase family.

269799:GMET RS13525
gene id: 269799:GMET_RS13525
uniprot id: Q39S58
names: Subcellular Location Annotation
messages: Membrane

269799:GMET RS06235
gene id: 269799:GMET_RS06235
uniprot id: Q39WA0
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

269799:GMET RS06925
gene id: 269799:GMET_RS06925
uniprot id: Q39VW5
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

269799:GMET RS00770
gene id: 269799:GMET_RS00770
uniprot id: Q39ZC4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cell inner membrane
messages: In the C-terminal section; belongs to the complex I 49 kDa subunit family.
messages: In the N-terminal section; belongs to the complex I 20 kDa subunit family.
messages: In the central section; belongs to the complex I 30 kDa subunit family.
messages: NDH-1 is composed of about 13 different subunits. Subunits NuoBCD, E, F, and G constitute the peripheral sector of the complex (By similarity).
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

269799:GMET RS09775
gene id: 269799:GMET_RS09775
uniprot id: Q39UB0
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

269799:GMET RS12280
gene id: 269799:GMET_RS12280
uniprot id: Q39SW0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Part of an ABC transporter complex. Responsible for energy coupling to the transport system.

269799:GMET RS09290
gene id: 269799:GMET_RS09290
uniprot id: Q39UK0
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.

269799:GMET RS10360
gene id: 269799:GMET_RS10360
uniprot id: Q39TZ2
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

269799:GMET RS11595
gene id: 269799:GMET_RS11595
uniprot id: Q39T99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

269799:GMET RS12590
gene id: 269799:GMET_RS12590
uniprot id: Q39SP7
names: Similarity
messages: Belongs to the YkuD family.

269799:GMET RS02415
gene id: 269799:GMET_RS02415
uniprot id: Q39YE8
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

269799:GMET RS16770
gene id: 269799:GMET_RS16770
uniprot id: Q39QB6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

269799:GMET RS17150
gene id: 269799:GMET_RS17150
uniprot id: Q39Q41
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

269799:GMET RS08050
gene id: 269799:GMET_RS08050
uniprot id: Q39V91
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

269799:GMET RS15605
gene id: 269799:GMET_RS15605
uniprot id: Q39QZ7
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

269799:GMET RS01895
gene id: 269799:GMET_RS01895
uniprot id: Q39YQ1
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

269799:GMET RS02965
gene id: 269799:GMET_RS02965
uniprot id: Q39Y37
names: Subcellular Location Annotation
messages: Membrane

269799:GMET RS00520
gene id: 269799:GMET_RS00520
uniprot id: Q39ZH2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.

269799:GMET RS02255
gene id: 269799:GMET_RS02255
uniprot id: Q39YI0
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Uronate isomerase family.

269799:GMET RS11730
gene id: 269799:GMET_RS11730
uniprot id: Q39T72
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

269799:GMET RS14410
gene id: 269799:GMET_RS14410
uniprot id: Q39RN5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

269799:GMET RS02050
gene id: 269799:GMET_RS02050
uniprot id: Q39YM1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

269799:GMET RS16015
gene id: 269799:GMET_RS16015
uniprot id: Q39QR5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

269799:GMET RS10350
gene id: 269799:GMET_RS10350
uniprot id: Q39TZ4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

269799:GMET RS07810
gene id: 269799:GMET_RS07810
uniprot id: Q39VD7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

269799:GMET RS16485
gene id: 269799:GMET_RS16485
uniprot id: Q39QH2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

269799:GMET RS14400
gene id: 269799:GMET_RS14400
uniprot id: Q39RN7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein S19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein S19.

269799:GMET RS03245
gene id: 269799:GMET_RS03245
uniprot id: Q39XY7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

269799:GMET RS11380
gene id: 269799:GMET_RS11380
uniprot id: Q39TE0
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

269799:GMET RS01680
gene id: 269799:GMET_RS01680
uniprot id: Q39YU5
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

269799:GMET RS01925
gene id: 269799:GMET_RS01925
uniprot id: Q39YP5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

269799:GMET RS02335
gene id: 269799:GMET_RS02335
uniprot id: Q39YG4
names: Function
names: Similarity
messages: Belongs to the CobT family.
messages: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).

269799:GMET RS15420
gene id: 269799:GMET_RS15420
uniprot id: Q39R33
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

269799:GMET RS03025
gene id: 269799:GMET_RS03025
uniprot id: Q39Y26
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

269799:GMET RS12045
gene id: 269799:GMET_RS12045
uniprot id: Q39T08
names: Similarity
messages: Belongs to the disproportionating enzyme family.

269799:GMET RS02470
gene id: 269799:GMET_RS02470
uniprot id: Q39YD6
names: Function
names: Similarity
messages: Belongs to the HPPK family.
messages: Catalyzes the transfer of pyrophosphate from adenosine triphosphate (ATP) to 6-hydroxymethyl-7,8-dihydropterin, an enzymatic step in folate biosynthesis pathway.

269799:GMET RS15890
gene id: 269799:GMET_RS15890
uniprot id: Q39QU0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Binds 1 Fe(3+) ion per subunit.
messages: Rubredoxin is a small nonheme, iron protein lacking acid-labile sulfide. Its single Fe, chelated to 4 Cys, functions as an electron acceptor and may also stabilize the conformation of the molecule.

269799:GMET RS11870
gene id: 269799:GMET_RS11870
uniprot id: Q39T44
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

269799:GMET RS14630
gene id: 269799:GMET_RS14630
uniprot id: Q39RJ2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

269799:GMET RS16615
gene id: 269799:GMET_RS16615
uniprot id: Q39QE6
names: Similarity
messages: Belongs to the ClpA/ClpB family.

269799:GMET RS00845
gene id: 269799:GMET_RS00845
uniprot id: Q39ZA9
names: Subcellular Location Annotation
messages: Membrane

269799:GMET RS06355
gene id: 269799:GMET_RS06355
uniprot id: Q39W76
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.

269799:GMET RS07935
gene id: 269799:GMET_RS07935
uniprot id: Q39VB4
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

269799:GMET RS11135
gene id: 269799:GMET_RS11135
uniprot id: Q39TI6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

269799:GMET RS16560
gene id: 269799:GMET_RS16560
uniprot id: Q39QF7
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

269799:GMET RS02855
gene id: 269799:GMET_RS02855
uniprot id: Q39Y59
names: Subcellular Location Annotation
messages: Membrane

269799:GMET RS02085
gene id: 269799:GMET_RS02085
uniprot id: Q39YL4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

269799:GMET RS11280
gene id: 269799:GMET_RS11280
uniprot id: Q39WR5
names: Function
names: Similarity
messages: Belongs to the transposase 11 family.
messages: Involved in the transposition of the insertion sequence IS5.

269799:GMET RS07640
gene id: 269799:GMET_RS07640
uniprot id: Q39VH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

269799:GMET RS03255
gene id: 269799:GMET_RS03255
uniprot id: Q39XY5
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

269799:GMET RS03110
gene id: 269799:GMET_RS03110
uniprot id: Q39Y15
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

269799:GMET RS00890
gene id: 269799:GMET_RS00890
uniprot id: Q39ZA0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

269799:GMET RS00450
gene id: 269799:GMET_RS00450
uniprot id: Q39ZI5
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

269799:GMET RS13795
gene id: 269799:GMET_RS13795
uniprot id: Q39S04
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

269799:GMET RS03015
gene id: 269799:GMET_RS03015
uniprot id: Q39Y28
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

269799:GMET RS13485
gene id: 269799:GMET_RS13485
uniprot id: Q39S67
names: Similarity
messages: Belongs to the citrate synthase family.

269799:GMET RS01935
gene id: 269799:GMET_RS01935
uniprot id: Q39YP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

269799:GMET RS16150
gene id: 269799:GMET_RS16150
uniprot id: Q39QN8
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

269799:GMET RS04840
gene id: 269799:GMET_RS04840
uniprot id: Q39X15
names: Similarity
messages: Belongs to the PilY1 family.

269799:GMET RS01255
gene id: 269799:GMET_RS01255
uniprot id: Q39Z29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

269799:GMET RS04605
gene id: 269799:GMET_RS04605
uniprot id: Q39X62
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIS family. GmhA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
messages: Cytoplasm
messages: Homotetramer.
messages: The reaction produces a racemic mixture of D-glycero-alpha-D-manno-heptose 7-phosphate and D-glycero-beta-D-manno-heptose 7-phosphate.

269799:GMET RS12860
gene id: 269799:GMET_RS12860
uniprot id: Q39SJ4
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

269799:GMET RS17585
gene id: 269799:GMET_RS17585
uniprot id: Q39PW1
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

269799:GMET RS07140
gene id: 269799:GMET_RS07140
uniprot id: Q39VS3
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

269799:GMET RS10070
gene id: 269799:GMET_RS10070
uniprot id: Q39U51
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

269799:GMET RS02730
gene id: 269799:GMET_RS02730
uniprot id: Q39Y84
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

269799:GMET RS01030
gene id: 269799:GMET_RS01030
uniprot id: Q39Z73
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm
messages: Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.

269799:GMET RS00675
gene id: 269799:GMET_RS00675
uniprot id: Q39ZE1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mediates influx of magnesium ions.
messages: Membrane

269799:GMET RS14925
gene id: 269799:GMET_RS14925
uniprot id: Q39RD3
names: Similarity
messages: Belongs to the prokaryotic/mitochondrial release factor family.

269799:GMET RS15965
gene id: 269799:GMET_RS15965
uniprot id: Q39QS5
names: Similarity
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.

269799:GMET RS17155
gene id: 269799:GMET_RS17155
uniprot id: Q39Q40
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

269799:GMET RS08395
gene id: 269799:GMET_RS08395
uniprot id: Q39V24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

269799:GMET RS13875
gene id: 269799:GMET_RS13875
uniprot id: Q39RY8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
messages: Homotetramer.
messages: Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.

269799:GMET RS10470
gene id: 269799:GMET_RS10470
uniprot id: Q39TX0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

269799:GMET RS04650
gene id: 269799:GMET_RS04650
uniprot id: Q39X53
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. MrdB/RodA subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell wall elongation.

269799:GMET RS03325
gene id: 269799:GMET_RS03325
uniprot id: Q39XX0
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the NifH/BchL/ChlL family.
messages: Binds 1 [4Fe-4S] cluster per dimer.
messages: Homodimer.
messages: The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein.
messages: The reversible ADP-ribosylation of Arg inactivates the nitrogenase reductase and regulates nitrogenase activity.
messages: The reversible ADP-ribosylation of Arg-99 inactivates the nitrogenase reductase and regulates nitrogenase activity.

269799:GMET RS14690
gene id: 269799:GMET_RS14690
uniprot id: Q39RI0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

269799:GMET RS10890
gene id: 269799:GMET_RS10890
uniprot id: Q39TN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family.
messages: Membrane

269799:GMET RS17015
gene id: 269799:GMET_RS17015
uniprot id: Q39Q67
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

269799:GMET RS08940
gene id: 269799:GMET_RS08940
uniprot id: Q39UR6
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

269799:GMET RS16570
gene id: 269799:GMET_RS16570
uniprot id: Q39QF5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

269799:GMET RS01880
gene id: 269799:GMET_RS01880
uniprot id: Q39YQ4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

269799:GMET RS07995
gene id: 269799:GMET_RS07995
uniprot id: Q39VA2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

269799:GMET RS13155
gene id: 269799:GMET_RS13155
uniprot id: Q39SD4
names: Similarity
messages: Belongs to the LacAB/RpiB family.

269799:GMET RS07490
gene id: 269799:GMET_RS07490
uniprot id: Q39VK3
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

269799:GMET RS16840
gene id: 269799:GMET_RS16840
uniprot id: Q39QA2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase C chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.

269799:GMET RS00430
gene id: 269799:GMET_RS00430
uniprot id: Q39ZI9
names: Subcellular Location Annotation
messages: Membrane

269799:GMET RS05345
gene id: 269799:GMET_RS05345
uniprot id: Q39WR9
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated protein Cas5 family. Subtype I-C/Dvulg subfamily.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).

269799:GMET RS12465
gene id: 269799:GMET_RS12465
uniprot id: Q39SS3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

269799:GMET RS03205
gene id: 269799:GMET_RS03205
uniprot id: Q39XZ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

269799:GMET RS09435
gene id: 269799:GMET_RS09435
uniprot id: Q39UH4
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

269799:GMET RS10475
gene id: 269799:GMET_RS10475
uniprot id: Q39TW9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhD family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.

269799:GMET RS04310
gene id: 269799:GMET_RS04310
uniprot id: Q39XC1
names: Similarity
messages: Belongs to the GSP E family.

269799:GMET RS12725
gene id: 269799:GMET_RS12725
uniprot id: Q39SM1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Cx-SAM synthase family.
messages: Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM).
messages: Homodimer.

269799:GMET RS01345
gene id: 269799:GMET_RS01345
uniprot id: Q39Z11
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

269799:GMET RS01525
gene id: 269799:GMET_RS01525
uniprot id: Q39YX5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PEPCase type 1 family.
messages: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
messages: Homotetramer.

269799:GMET RS02355
gene id: 269799:GMET_RS02355
uniprot id: Q39YG0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ThiC family. 5-hydroxybenzimidazole synthase subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of aminoimidazole ribotide (AIR) to 5-hydroxybenzimidazole (5-HBI) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Is thus involved in the anaerobic biosynthesis of the benzimidazole lower axial ligand of the cobamide produced by G.metallireducens.
messages: Homodimer.

269799:GMET RS04270
gene id: 269799:GMET_RS04270
uniprot id: Q39XC9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YajC family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the SecDF-YidC-YajC translocase complex. The SecDF-YidC-YajC translocase forms a supercomplex with SecYEG, called the holo-translocon (HTL).
messages: The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions.

269799:GMET RS12410
gene id: 269799:GMET_RS12410
uniprot id: Q39ST4
names: Subcellular Location Annotation
messages: Membrane

269799:GMET RS06430
gene id: 269799:GMET_RS06430
uniprot id: Q39W61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

269799:GMET RS12495
gene id: 269799:GMET_RS12495
uniprot id: Q39SR7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

269799:GMET RS13655
gene id: 269799:GMET_RS13655
uniprot id: Q39S32
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

269799:GMET RS07790
gene id: 269799:GMET_RS07790
uniprot id: Q39VE2
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

269799:GMET RS03100
gene id: 269799:GMET_RS03100
uniprot id: Q39Y17
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

269799:GMET RS02810
gene id: 269799:GMET_RS02810
uniprot id: Q39Y68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

269799:GMET RS16685
gene id: 269799:GMET_RS16685
uniprot id: Q39QD2
names: Similarity
messages: Belongs to the peptidase A31 family.

269799:GMET RS09585
gene id: 269799:GMET_RS09585
uniprot id: Q39UE9
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

269799:GMET RS11375
gene id: 269799:GMET_RS11375
uniprot id: Q39TE1
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

269799:GMET RS08550
gene id: 269799:GMET_RS08550
uniprot id: Q39UZ4
names: Subcellular Location Annotation
messages: Membrane

269799:GMET RS05180
gene id: 269799:GMET_RS05180
uniprot id: Q39WU9
names: Similarity
messages: Belongs to the phosphate acetyltransferase and butyryltransferase family.

269799:GMET RS17770
gene id: 269799:GMET_RS17770
uniprot id: Q39PS7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CpoB family.
messages: Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division.
messages: Periplasm

269799:GMET RS11055
gene id: 269799:GMET_RS11055
uniprot id: Q39TK2
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

269799:GMET RS17395
gene id: 269799:GMET_RS17395
uniprot id: Q39PZ6
names: Similarity
messages: Belongs to the aminoglycoside phosphotransferase family.
messages: Belongs to the glycosyl hydrolase 13 family. TreS subfamily.

269799:GMET RS12285
gene id: 269799:GMET_RS12285
uniprot id: Q39SV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CbiQ family.
messages: Membrane

269799:GMET RS13620
gene id: 269799:GMET_RS13620
uniprot id: Q39S39
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

269799:GMET RS11065
gene id: 269799:GMET_RS11065
uniprot id: Q39TK0
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

269799:GMET RS06475
gene id: 269799:GMET_RS06475
uniprot id: Q39W52
names: Function
names: Similarity
messages: Belongs to the RapZ-like family.
messages: Displays ATPase and GTPase activities.

269799:GMET RS08145
gene id: 269799:GMET_RS08145
uniprot id: Q39V72
names: Similarity
messages: Belongs to the prokaryotic/mitochondrial release factor family.

269799:GMET RS17085
gene id: 269799:GMET_RS17085
uniprot id: Q39Q54
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

269799:GMET RS13635
gene id: 269799:GMET_RS13635
uniprot id: Q39S36
names: Similarity
messages: Belongs to the peptidase U62 family.

269799:GMET RS07250
gene id: 269799:GMET_RS07250
uniprot id: Q39VQ1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

269799:GMET RS00305
gene id: 269799:GMET_RS00305
uniprot id: Q39ZL4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SelA family.
messages: Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.
messages: Cytoplasm

269799:GMET RS06990
gene id: 269799:GMET_RS06990
uniprot id: Q39VV2
names: Function
names: Similarity
messages: Belongs to the ribF family.
messages: Catalyzes the phosphorylation of riboflavin to FMN followed by the adenylation of FMN to FAD.

269799:GMET RS00600
gene id: 269799:GMET_RS00600
uniprot id: Q39ZF6
names: Function
names: Similarity
messages: Belongs to the carbamoyltransferase HypF family.
messages: Involved in the maturation of [NiFe] hydrogenases. Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of [NiFe]-hydrogenases. HypF functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide.

269799:GMET RS15265
gene id: 269799:GMET_RS15265
uniprot id: Q39R65
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

269799:GMET RS08240
gene id: 269799:GMET_RS08240
uniprot id: Q39V53
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

269799:GMET RS01040
gene id: 269799:GMET_RS01040
uniprot id: Q39Z71
names: Similarity
messages: Belongs to the Nudix hydrolase family.

269799:GMET RS10440
gene id: 269799:GMET_RS10440
uniprot id: Q39TX6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

269799:GMET RS06815
gene id: 269799:GMET_RS06815
uniprot id: Q39VY5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the OMP decarboxylase family. Type 1 subfamily.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
messages: Homodimer.

269799:GMET RS16285
gene id: 269799:GMET_RS16285
uniprot id: Q39QL1
names: Caution
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

269799:GMET RS08070
gene id: 269799:GMET_RS08070
uniprot id: Q39V87
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.

269799:GMET RS16965
gene id: 269799:GMET_RS16965
uniprot id: Q39Q77
names: Similarity
messages: Belongs to the peptidase M20A family.

269799:GMET RS17140
gene id: 269799:GMET_RS17140
uniprot id: Q39Q43
names: Cofactor
names: Similarity
messages: Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.
messages: Binds 3 [4Fe-4S] clusters per subunit.

269799:GMET RS07670
gene id: 269799:GMET_RS07670
uniprot id: Q39VG7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

269799:GMET RS06340
gene id: 269799:GMET_RS06340
uniprot id: Q39W79
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.

269799:GMET RS16200
gene id: 269799:GMET_RS16200
uniprot id: Q39QM8
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

269799:GMET RS01475
gene id: 269799:GMET_RS01475
uniprot id: Q39YY5
names: Similarity
messages: Belongs to the cytochrome c-552 family.

269799:GMET RS06805
gene id: 269799:GMET_RS06805
uniprot id: Q39VY7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

269799:GMET RS08850
gene id: 269799:GMET_RS08850
uniprot id: Q39UT4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

269799:GMET RS04965
gene id: 269799:GMET_RS04965
uniprot id: Q39WZ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
messages: Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Seems to participate in the biosynthesis of the nitrogenase metalloclusters by providing the inorganic sulfur required for the Fe-S core formation.
messages: Homodimer.

269799:GMET RS08930
gene id: 269799:GMET_RS08930
uniprot id: Q39UR8
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

269799:GMET RS03725
gene id: 269799:GMET_RS03725
uniprot id: Q39XN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

269799:GMET RS03875
gene id: 269799:GMET_RS03875
uniprot id: Q39XK8
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.

269799:GMET RS04525
gene id: 269799:GMET_RS04525
uniprot id: Q39X78
names: Function
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily.
messages: Catalyzes the biosynthesis of agmatine from arginine.

269799:GMET RS17720
gene id: 269799:GMET_RS17720
uniprot id: Q39PT7
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

269799:GMET RS02300
gene id: 269799:GMET_RS02300
uniprot id: Q39YH1
names: Similarity
messages: Belongs to the MotB family.

269799:GMET RS17220
gene id: 269799:GMET_RS17220
uniprot id: Q39Q28
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

269799:GMET RS06305
gene id: 269799:GMET_RS06305
uniprot id: Q39W86
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by GTP. Inhibited by UTP.
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.

269799:GMET RS07180
gene id: 269799:GMET_RS07180
uniprot id: Q39VR6
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

269799:GMET RS05325
gene id: 269799:GMET_RS05325
uniprot id: Q39WS3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

269799:GMET RS03135
gene id: 269799:GMET_RS03135
uniprot id: Q39Y10
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

269799:GMET RS05570
gene id: 269799:GMET_RS05570
uniprot id: Q39WM4
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

269799:GMET RS03485
gene id: 269799:GMET_RS03485
uniprot id: Q39XT8
names: Similarity
messages: Belongs to the P(II) protein family.

269799:GMET RS08055
gene id: 269799:GMET_RS08055
uniprot id: Q39V90
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

269799:GMET RS15515
gene id: 269799:GMET_RS15515
uniprot id: Q39R15
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliR/MopE/SpaR family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Role in flagellar biosynthesis.

269799:GMET RS03265
gene id: 269799:GMET_RS03265
uniprot id: Q39XY2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

269799:GMET RS06300
gene id: 269799:GMET_RS06300
uniprot id: Q39W87
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

269799:GMET RS16020
gene id: 269799:GMET_RS16020
uniprot id: Q39QR4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

269799:GMET RS07945
gene id: 269799:GMET_RS07945
uniprot id: Q39VB2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
messages: Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

269799:GMET RS12135
gene id: 269799:GMET_RS12135
uniprot id: Q39SY9
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.

269799:GMET RS06080
gene id: 269799:GMET_RS06080
uniprot id: Q39WC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

269799:GMET RS02205
gene id: 269799:GMET_RS02205
uniprot id: Q39YJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin. Binds to flagellin and participates in the assembly of the flagellum.
messages: Belongs to the FliW family.
messages: Cytoplasm
messages: Interacts with translational regulator CsrA and flagellin(s).

269799:GMET RS04085
gene id: 269799:GMET_RS04085
uniprot id: Q39XG6
names: Function
messages: Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.

269799:GMET RS04345
gene id: 269799:GMET_RS04345
uniprot id: Q39XB4
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

269799:GMET RS16850
gene id: 269799:GMET_RS16850
uniprot id: Q39QA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1C family.
messages: Periplasm

269799:GMET RS07170
gene id: 269799:GMET_RS07170
uniprot id: Q39VR8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

269799:GMET RS00850
gene id: 269799:GMET_RS00850
uniprot id: Q39ZA8
names: Subcellular Location Annotation
messages: Membrane

269799:GMET RS11955
gene id: 269799:GMET_RS11955
uniprot id: Q39T27
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

269799:GMET RS05985
gene id: 269799:GMET_RS05985
uniprot id: Q39WE8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mediates influx of magnesium ions.
messages: Membrane

269799:GMET RS05410
gene id: 269799:GMET_RS05410
uniprot id: Q39WQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

269799:GMET RS13540
gene id: 269799:GMET_RS13540
uniprot id: Q39S55
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PstS family.
messages: Part of the ABC transporter complex PstSACB involved in phosphate import.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

269799:GMET RS05435
gene id: 269799:GMET_RS05435
uniprot id: Q39WQ1
names: Subcellular Location Annotation
messages: Membrane

269799:GMET RS10000
gene id: 269799:GMET_RS10000
uniprot id: Q39U65
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nurim family.
messages: Catalyzes the methylation of methanethiol (MeSH) to yield dimethylsulphide (DMS).
messages: Membrane

269799:GMET RS09810
gene id: 269799:GMET_RS09810
uniprot id: Q39UA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

269799:GMET RS00670
gene id: 269799:GMET_RS00670
uniprot id: Q39ZE2
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

269799:GMET RS15680
gene id: 269799:GMET_RS15680
uniprot id: Q39QY2
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

269799:GMET RS10595
gene id: 269799:GMET_RS10595
uniprot id: Q39TU4
names: Function
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

269799:GMET RS07120
gene id: 269799:GMET_RS07120
uniprot id: Q39VS7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

269799:GMET RS01875
gene id: 269799:GMET_RS01875
uniprot id: Q39YQ5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

269799:GMET RS01830
gene id: 269799:GMET_RS01830
uniprot id: Q39YR4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Essential cell division protein that coordinates cell division and chromosome segregation. The N-terminus is involved in assembly of the cell-division machinery. The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the dif recombination site, which is located within the replication terminus region. Translocation stops specifically at Xer-dif sites, where FtsK interacts with the Xer recombinase, allowing activation of chromosome unlinking by recombination. FtsK orienting polar sequences (KOPS) guide the direction of DNA translocation. FtsK can remove proteins from DNA as it translocates, but translocation stops specifically at XerCD-dif site, thereby preventing removal of XerC and XerD from dif.
messages: Homohexamer. Forms a ring that surrounds DNA.
messages: Membrane

269799:GMET RS08295
gene id: 269799:GMET_RS08295
uniprot id: Q39V44
names: Similarity
messages: Belongs to the Skp family.

269799:GMET RS01260
gene id: 269799:GMET_RS01260
uniprot id: Q39Z28
names: Subcellular Location Annotation
messages: Membrane

269799:GMET RS16575
gene id: 269799:GMET_RS16575
uniprot id: Q39QF4
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

269799:GMET RS06470
gene id: 269799:GMET_RS06470
uniprot id: Q39W53
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HPrK/P family.
messages: Both phosphorylation and phosphorolysis are carried out by the same active site and suggest a common mechanism for both reactions.
messages: Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr).
messages: Homohexamer.
messages: The Walker A ATP-binding motif also binds Pi and PPi.

269799:GMET RS06980
gene id: 269799:GMET_RS06980
uniprot id: Q39VV4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

269799:GMET RS02135
gene id: 269799:GMET_RS02135
uniprot id: Q39YK4
names: Function
names: Similarity
messages: Belongs to the GTP-binding SRP family.
messages: Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum.

269799:GMET RS08530
gene id: 269799:GMET_RS08530
uniprot id: Q39UZ8
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

269799:GMET RS15390
gene id: 269799:GMET_RS15390
uniprot id: Q39R39
names: Subcellular Location Annotation
messages: Membrane

269799:GMET RS06490
gene id: 269799:GMET_RS06490
uniprot id: Q39W49
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

269799:GMET RS16640
gene id: 269799:GMET_RS16640
uniprot id: Q39QE1
names: Similarity
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.

269799:GMET RS06935
gene id: 269799:GMET_RS06935
uniprot id: Q39VW3
names: Similarity
messages: Belongs to the transglycosylase Slt family.

269799:GMET RS06615
gene id: 269799:GMET_RS06615
uniprot id: Q39W26
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. Fucose synthase subfamily.
messages: Catalyzes the two-step NADP-dependent conversion of GDP-4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction.

269799:GMET RS08895
gene id: 269799:GMET_RS08895
uniprot id: Q39US5
names: Function
names: Similarity
messages: Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
messages: Regulates the transcription of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines.

269799:GMET RS03195
gene id: 269799:GMET_RS03195
uniprot id: Q39XZ8
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

269799:GMET RS13130
gene id: 269799:GMET_RS13130
uniprot id: Q39SD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ribonuclease N1/T1 family.
messages: Secreted

269799:GMET RS15645
gene id: 269799:GMET_RS15645
uniprot id: Q39QY9
names: Similarity
messages: Belongs to the hemerythrin family.

269799:GMET RS12770
gene id: 269799:GMET_RS12770
uniprot id: Q39SL2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MlaE permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

269799:GMET RS16040
gene id: 269799:GMET_RS16040
uniprot id: Q39QR0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein L14 (rplN).

269799:GMET RS12525
gene id: 269799:GMET_RS12525
uniprot id: Q39WR5
names: Function
names: Similarity
messages: Belongs to the transposase 11 family.
messages: Involved in the transposition of the insertion sequence IS5.

269799:GMET RS01665
gene id: 269799:GMET_RS01665
uniprot id: Q39YU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
messages: Membrane

269799:GMET RS00710
gene id: 269799:GMET_RS00710
uniprot id: Q39ZD4
names: Subcellular Location Annotation
messages: Membrane

269799:GMET RS16970
gene id: 269799:GMET_RS16970
uniprot id: Q39Q76
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

269799:GMET RS01685
gene id: 269799:GMET_RS01685
uniprot id: Q39YU4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

269799:GMET RS07010
gene id: 269799:GMET_RS07010
uniprot id: Q39VU8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).

269799:GMET RS07160
gene id: 269799:GMET_RS07160
uniprot id: Q39VS0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
messages: Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.
messages: Cytoplasm

269799:GMET RS11710
gene id: 269799:GMET_RS11710
uniprot id: Q39T76
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

269799:GMET RS15945
gene id: 269799:GMET_RS15945
uniprot id: Q39QS9
names: Function
names: Similarity
messages: Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control.
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

269799:GMET RS09645
gene id: 269799:GMET_RS09645
uniprot id: Q39UD7
names: Function
names: Similarity
messages: Belongs to the bacterioferritin family.
messages: Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex.

269799:GMET RS06220
gene id: 269799:GMET_RS06220
uniprot id: Q39WA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

269799:GMET RS10740
gene id: 269799:GMET_RS10740
uniprot id: Q39TR4
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

269799:GMET RS06440
gene id: 269799:GMET_RS06440
uniprot id: Q39W59
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Homotetramer.

269799:GMET RS00260
gene id: 269799:GMET_RS00260
uniprot id: Q39ZM3
names: Similarity
messages: Belongs to the peptidase M16 family.

269799:GMET RS13900
gene id: 269799:GMET_RS13900
uniprot id: Q39RY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

269799:GMET RS03405
gene id: 269799:GMET_RS03405
uniprot id: Q39XV4
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

269799:GMET RS04925
gene id: 269799:GMET_RS04925
uniprot id: Q39WZ8
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

269799:GMET RS17145
gene id: 269799:GMET_RS17145
uniprot id: Q39Q42
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

269799:GMET RS16830
gene id: 269799:GMET_RS16830
uniprot id: Q39QA4
names: Subcellular Location Annotation
messages: Membrane

269799:GMET RS00145
gene id: 269799:GMET_RS00145
uniprot id: Q39ZP5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

269799:GMET RS06370
gene id: 269799:GMET_RS06370
uniprot id: Q39W73
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homotetramer.

269799:GMET RS16995
gene id: 269799:GMET_RS16995
uniprot id: Q39Q71
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the radical SAM superfamily. MqnE family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3-[(1-carboxyvinyl)oxy]benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate.

269799:GMET RS04265
gene id: 269799:GMET_RS04265
uniprot id: Q39XD0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

269799:GMET RS12260
gene id: 269799:GMET_RS12260
uniprot id: Q39SW4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpC family.
messages: Cell inner membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

269799:GMET RS08475
gene id: 269799:GMET_RS08475
uniprot id: Q39V09
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

269799:GMET RS13725
gene id: 269799:GMET_RS13725
uniprot id: Q39S18
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

269799:GMET RS03930
gene id: 269799:GMET_RS03930
uniprot id: Q39XJ7
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

269799:GMET RS15525
gene id: 269799:GMET_RS15525
uniprot id: Q39R13
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliP/MopC/SpaP family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a role in the flagellum-specific transport system.

269799:GMET RS06950
gene id: 269799:GMET_RS06950
uniprot id: Q39VW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbA subfamily.
messages: Periplasm

269799:GMET RS15250
gene id: 269799:GMET_RS15250
uniprot id: Q39R68
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

269799:GMET RS04995
gene id: 269799:GMET_RS04995
uniprot id: Q39WY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

269799:GMET RS16110
gene id: 269799:GMET_RS16110
uniprot id: Q39QP6
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

269799:GMET RS03645
gene id: 269799:GMET_RS03645
uniprot id: Q39XQ5
names: Similarity
messages: Belongs to the UPF0047 family.

269799:GMET RS07495
gene id: 269799:GMET_RS07495
uniprot id: Q39VK2
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.
messages: Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

269799:GMET RS13140
gene id: 269799:GMET_RS13140
uniprot id: Q39SD7
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

269799:GMET RS08315
gene id: 269799:GMET_RS08315
uniprot id: Q39V40
names: Function
names: Similarity
names: Subunit
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Homodimer.

269799:GMET RS08370
gene id: 269799:GMET_RS08370
uniprot id: Q39V29
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

269799:GMET RS12775
gene id: 269799:GMET_RS12775
uniprot id: Q39SL1
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

269799:GMET RS03115
gene id: 269799:GMET_RS03115
uniprot id: Q39Y14
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

269799:GMET RS04920
gene id: 269799:GMET_RS04920
uniprot id: Q39WZ9
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

269799:GMET RS13590
gene id: 269799:GMET_RS13590
uniprot id: Q39S45
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

269799:GMET RS05330
gene id: 269799:GMET_RS05330
uniprot id: Q39WS2
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FdhD family.
messages: Belongs to the MobA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.
messages: The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.
messages: Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.

269799:GMET RS14970
gene id: 269799:GMET_RS14970
uniprot id: Q39RC3
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

269799:GMET RS04705
gene id: 269799:GMET_RS04705
uniprot id: Q39X42
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

269799:GMET RS06920
gene id: 269799:GMET_RS06920
uniprot id: Q39VW6
names: Subcellular Location Annotation
messages: Membrane

269799:GMET RS02305
gene id: 269799:GMET_RS02305
uniprot id: Q39YH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Membrane

269799:GMET RS09125
gene id: 269799:GMET_RS09125
uniprot id: Q39UN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

269799:GMET RS07685
gene id: 269799:GMET_RS07685
uniprot id: Q39VG4
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

269799:GMET RS06275
gene id: 269799:GMET_RS06275
uniprot id: Q39W92
names: Similarity
messages: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family.
messages: Belongs to the radical SAM superfamily. NifB family.

269799:GMET RS14405
gene id: 269799:GMET_RS14405
uniprot id: Q39RN6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A probable RNA chaperone. Forms a complex with KhpB which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm
messages: Forms a complex with KhpB.

269799:GMET RS13260
gene id: 269799:GMET_RS13260
uniprot id: Q39SB2
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

269799:GMET RS03280
gene id: 269799:GMET_RS03280
uniprot id: Q39XX9
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

269799:GMET RS00830
gene id: 269799:GMET_RS00830
uniprot id: Q39ZB2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

269799:GMET RS14800
gene id: 269799:GMET_RS14800
uniprot id: Q39RF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

269799:GMET RS06195
gene id: 269799:GMET_RS06195
uniprot id: Q39WA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

269799:GMET RS08340
gene id: 269799:GMET_RS08340
uniprot id: Q39V35
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

269799:GMET RS13665
gene id: 269799:GMET_RS13665
uniprot id: Q39S30
names: Subcellular Location Annotation
messages: Membrane

269799:GMET RS16765
gene id: 269799:GMET_RS16765
uniprot id: Q39QB7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

269799:GMET RS14960
gene id: 269799:GMET_RS14960
uniprot id: Q39RC6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
messages: Single-chain monomer with multiple functions.

269799:GMET RS04000
gene id: 269799:GMET_RS04000
uniprot id: Q39XI3
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

269799:GMET RS03020
gene id: 269799:GMET_RS03020
uniprot id: Q39Y27
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

269799:GMET RS09345
gene id: 269799:GMET_RS09345
uniprot id: Q39UI9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division. Important for assembly or stability of the septal ring.

269799:GMET RS17045
gene id: 269799:GMET_RS17045
uniprot id: Q39Q62
names: Similarity
messages: Belongs to the GSP E family.

269799:GMET RS01945
gene id: 269799:GMET_RS01945
uniprot id: Q39YP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA-PH family.
messages: Cytoplasm

269799:GMET RS05480
gene id: 269799:GMET_RS05480
uniprot id: Q39WP2
names: Similarity
messages: Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.

269799:GMET RS07965
gene id: 269799:GMET_RS07965
uniprot id: Q39VA8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

269799:GMET RS13560
gene id: 269799:GMET_RS13560
uniprot id: Q39S51
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

269799:GMET RS12200
gene id: 269799:GMET_RS12200
uniprot id: Q39SX6
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

269799:GMET RS04960
gene id: 269799:GMET_RS04960
uniprot id: Q39WZ1
names: Function
names: Similarity
messages: Belongs to the NifU family.
messages: May be involved in the formation or repair of [Fe-S] clusters present in iron-sulfur proteins.

269799:GMET RS17875
gene id: 269799:GMET_RS17875
uniprot id: Q39PQ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

269799:GMET RS15785
gene id: 269799:GMET_RS15785
uniprot id: Q39QW1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

269799:GMET RS13435
gene id: 269799:GMET_RS13435
uniprot id: Q39S78
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

269799:GMET RS14775
gene id: 269799:GMET_RS14775
uniprot id: Q39RG3
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

269799:GMET RS03975
gene id: 269799:GMET_RS03975
uniprot id: Q39XI8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

269799:GMET RS00930
gene id: 269799:GMET_RS00930
uniprot id: Q39Z93
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RdgC family.
messages: May be involved in recombination.
messages: nucleoid

269799:GMET RS15880
gene id: 269799:GMET_RS15880
uniprot id: Q39QU2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Cytoplasm
messages: Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.

269799:GMET RS15510
gene id: 269799:GMET_RS15510
uniprot id: Q39R16
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type III secretion exporter family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

269799:GMET RS09745
gene id: 269799:GMET_RS09745
uniprot id: Q39UB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

269799:GMET RS17735
gene id: 269799:GMET_RS17735
uniprot id: Q39PT4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

269799:GMET RS09705
gene id: 269799:GMET_RS09705
uniprot id: Q39UC4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FBPase class 1 family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.

269799:GMET RS02560
gene id: 269799:GMET_RS02560
uniprot id: Q39YB8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

269799:GMET RS14295
gene id: 269799:GMET_RS14295
uniprot id: Q39RQ3
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

269799:GMET RS04890
gene id: 269799:GMET_RS04890
uniprot id: Q39X05
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Monomer.

269799:GMET RS00445
gene id: 269799:GMET_RS00445
uniprot id: Q39ZI6
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

269799:GMET RS14270
gene id: 269799:GMET_RS14270
uniprot id: Q39RQ8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

269799:GMET RS07080
gene id: 269799:GMET_RS07080
uniprot id: Q39VT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

269799:GMET RS01750
gene id: 269799:GMET_RS01750
uniprot id: Q39YT0
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

269799:GMET RS04485
gene id: 269799:GMET_RS04485
uniprot id: Q39X87
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

269799:GMET RS14015
gene id: 269799:GMET_RS14015
uniprot id: Q39WL7
names: Similarity
messages: Belongs to the transposase IS21/IS408/IS1162 family.

269799:GMET RS02390
gene id: 269799:GMET_RS02390
uniprot id: Q39YF3
names: Function
names: Similarity
messages: Belongs to the CbiD family.
messages: Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.

269799:GMET RS14255
gene id: 269799:GMET_RS14255
uniprot id: Q39RR1
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

269799:GMET RS07130
gene id: 269799:GMET_RS07130
uniprot id: Q39VS5
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

269799:GMET RS04375
gene id: 269799:GMET_RS04375
uniprot id: Q39XA9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm

269799:GMET RS13675
gene id: 269799:GMET_RS13675
uniprot id: Q39S28
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

269799:GMET RS00580
gene id: 269799:GMET_RS00580
uniprot id: Q39ZG0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

269799:GMET RS02150
gene id: 269799:GMET_RS02150
uniprot id: Q39YK1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of five rings (E,L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

269799:GMET RS03330
gene id: 269799:GMET_RS03330
uniprot id: Q39XW9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NifD/NifK/NifE/NifN family.
messages: Tetramer of two alpha and two beta chains. Forms complex with the iron protein (nitrogenase component 2).
messages: This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation.

269799:GMET RS09445
gene id: 269799:GMET_RS09445
uniprot id: Q39UH2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

269799:GMET RS06295
gene id: 269799:GMET_RS06295
uniprot id: Q39W88
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

269799:GMET RS01840
gene id: 269799:GMET_RS01840
uniprot id: Q39YR2
names: Similarity
messages: Belongs to the FrhG family.

269799:GMET RS12960
gene id: 269799:GMET_RS12960
uniprot id: Q39SH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

269799:GMET RS08010
gene id: 269799:GMET_RS08010
uniprot id: Q39V99
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

269799:GMET RS02065
gene id: 269799:GMET_RS02065
uniprot id: Q39YL8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

269799:GMET RS02060
gene id: 269799:GMET_RS02060
uniprot id: Q39YL9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell inner membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).

269799:GMET RS04535
gene id: 269799:GMET_RS04535
uniprot id: Q39X76
names: Subcellular Location Annotation
messages: Membrane

269799:GMET RS12145
gene id: 269799:GMET_RS12145
uniprot id: Q39SY7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

269799:GMET RS11685
gene id: 269799:GMET_RS11685
uniprot id: Q39T81
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

269799:GMET RS09545
gene id: 269799:GMET_RS09545
uniprot id: Q39UF6
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

269799:GMET RS05640
gene id: 269799:GMET_RS05640
uniprot id: Q39WL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetate uptake transporter (AceTr) (TC 2.A.96) family.
messages: Membrane

269799:GMET RS07485
gene id: 269799:GMET_RS07485
uniprot id: Q39VK4
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

269799:GMET RS04275
gene id: 269799:GMET_RS04275
uniprot id: Q39XC8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

269799:GMET RS09660
gene id: 269799:GMET_RS09660
uniprot id: Q39UD3
names: Cofactor
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Binds 1 [4Fe-4S] cluster per subunit.

269799:GMET RS16050
gene id: 269799:GMET_RS16050
uniprot id: Q39QQ8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

269799:GMET RS09390
gene id: 269799:GMET_RS09390
uniprot id: Q39UI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

269799:GMET RS02555
gene id: 269799:GMET_RS02555
uniprot id: Q39YB9
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

269799:GMET RS06560
gene id: 269799:GMET_RS06560
uniprot id: Q39W35
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

269799:GMET RS05070
gene id: 269799:GMET_RS05070
uniprot id: Q39WW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1C family.
messages: Periplasm

269799:GMET RS09670
gene id: 269799:GMET_RS09670
uniprot id: Q39UD1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

269799:GMET RS09805
gene id: 269799:GMET_RS09805
uniprot id: Q39UA4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

269799:GMET RS05465
gene id: 269799:GMET_RS05465
uniprot id: Q39WP5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell inner membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

269799:GMET RS14190
gene id: 269799:GMET_RS14190
uniprot id: Q39RS4
names: Similarity
messages: Belongs to the UPF0751 family.

269799:GMET RS03250
gene id: 269799:GMET_RS03250
uniprot id: Q39XY6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell inner membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

269799:GMET RS06835
gene id: 269799:GMET_RS06835
uniprot id: Q39VY3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.

269799:GMET RS06375
gene id: 269799:GMET_RS06375
uniprot id: Q39W72
names: Subcellular Location Annotation
messages: Cytoplasm

269799:GMET RS06520
gene id: 269799:GMET_RS06520
uniprot id: Q39W43
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

269799:GMET RS02130
gene id: 269799:GMET_RS02130
uniprot id: Q39YK5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

269799:GMET RS03490
gene id: 269799:GMET_RS03490
uniprot id: Q39XT7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

269799:GMET RS06995
gene id: 269799:GMET_RS06995
uniprot id: Q39VV1
names: Subcellular Location Annotation
messages: Membrane

269799:GMET RS04740
gene id: 269799:GMET_RS04740
uniprot id: Q39X35
names: Similarity
messages: Belongs to the peptidase U62 family.

269799:GMET RS05300
gene id: 269799:GMET_RS05300
uniprot id: Q39WS7
names: Subcellular Location Annotation
messages: Membrane

269799:GMET RS05770
gene id: 269799:GMET_RS05770
uniprot id: Q39WI5
names: Subcellular Location Annotation
messages: Membrane

269799:GMET RS11835
gene id: 269799:GMET_RS11835
uniprot id: Q39T51
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Cell inner membrane
messages: Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.

269799:GMET RS14280
gene id: 269799:GMET_RS14280
uniprot id: Q39RQ7
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

269799:GMET RS05175
gene id: 269799:GMET_RS05175
uniprot id: Q39WV0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

269799:GMET RS14200
gene id: 269799:GMET_RS14200
uniprot id: Q39RS2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HCP family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Binds 1 hybrid [4Fe-2O-2S] cluster.
messages: Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
messages: Cytoplasm

269799:GMET RS09305
gene id: 269799:GMET_RS09305
uniprot id: Q39UJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

269799:GMET RS02890
gene id: 269799:GMET_RS02890
uniprot id: Q39Y52
names: Subcellular Location Annotation
messages: Membrane

269799:GMET RS08170
gene id: 269799:GMET_RS08170
uniprot id: Q39V67
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

269799:GMET RS01240
gene id: 269799:GMET_RS01240
uniprot id: Q39Z32
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

269799:GMET RS15695
gene id: 269799:GMET_RS15695
uniprot id: Q39QX9
names: Subcellular Location Annotation
messages: Membrane

269799:GMET RS15910
gene id: 269799:GMET_RS15910
uniprot id: Q39QT6
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
messages: Synthesizes alpha-1,4-glucan chains using ADP-glucose.

269799:GMET RS16330
gene id: 269799:GMET_RS16330
uniprot id: Q39QK2
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
messages: This function is generally fulfilled by the C-terminal part of HisG, which is missing in some bacteria such as this one.

269799:GMET RS08270
gene id: 269799:GMET_RS08270
uniprot id: Q39V47
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

269799:GMET RS02615
gene id: 269799:GMET_RS02615
uniprot id: Q39YA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

269799:GMET RS03510
gene id: 269799:GMET_RS03510
uniprot id: Q39XT3
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

269799:GMET RS00375
gene id: 269799:GMET_RS00375
uniprot id: Q39ZK0
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

269799:GMET RS16325
gene id: 269799:GMET_RS16325
uniprot id: Q39QK3
names: Similarity
messages: Belongs to the HepT RNase toxin family.

269799:GMET RS15795
gene id: 269799:GMET_RS15795
uniprot id: Q39QV9
names: Function
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.

269799:GMET RS14600
gene id: 269799:GMET_RS14600
uniprot id: Q39RJ7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).

269799:GMET RS17760
gene id: 269799:GMET_RS17760
uniprot id: Q39PS9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TolB family.
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: Periplasm
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

269799:GMET RS01930
gene id: 269799:GMET_RS01930
uniprot id: Q39YP4
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

269799:GMET RS08630
gene id: 269799:GMET_RS08630
uniprot id: Q39UX8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

269799:GMET RS07835
gene id: 269799:GMET_RS07835
uniprot id: Q39VD2
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

269799:GMET RS01995
gene id: 269799:GMET_RS01995
uniprot id: Q39YN2
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

269799:GMET RS00920
gene id: 269799:GMET_RS00920
uniprot id: Q39Z95
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peroxiredoxin family. Tpx subfamily.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

269799:GMET RS09360
gene id: 269799:GMET_RS09360
uniprot id: Q39UI6
names: Similarity
messages: Belongs to the bacterial secretin family.

269799:GMET RS01545
gene id: 269799:GMET_RS01545
uniprot id: Q39YX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Cell inner membrane
messages: Membrane

269799:GMET RS03155
gene id: 269799:GMET_RS03155
uniprot id: Q39Y06
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

269799:GMET RS14325
gene id: 269799:GMET_RS14325
uniprot id: Q39RP7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PAPS reductase family. CysD subfamily.
messages: Heterodimer composed of CysD, the smaller subunit, and CysN.
messages: With CysN forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.

269799:GMET RS11930
gene id: 269799:GMET_RS11930
uniprot id: Q39T32
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell inner membrane

269799:GMET RS17100
gene id: 269799:GMET_RS17100
uniprot id: Q39Q51
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell inner membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

269799:GMET RS04325
gene id: 269799:GMET_RS04325
uniprot id: Q39XB8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Monomer.

269799:GMET RS14380
gene id: 269799:GMET_RS14380
uniprot id: Q39RP1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

269799:GMET RS15225
gene id: 269799:GMET_RS15225
uniprot id: Q39R73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

269799:GMET RS05845
gene id: 269799:GMET_RS05845
uniprot id: Q39WH0
names: Similarity
messages: Belongs to the YggT family.

269799:GMET RS02410
gene id: 269799:GMET_RS02410
uniprot id: Q39YE9
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

269799:GMET RS00745
gene id: 269799:GMET_RS00745
uniprot id: Q39ZC7
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

269799:GMET RS15410
gene id: 269799:GMET_RS15410
uniprot id: Q39R35
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).

269799:GMET RS17095
gene id: 269799:GMET_RS17095
uniprot id: Q39Q52
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell inner membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.

269799:GMET RS01130
gene id: 269799:GMET_RS01130
uniprot id: Q39Z54
names: Subcellular Location Annotation
messages: Membrane

269799:GMET RS14565
gene id: 269799:GMET_RS14565
uniprot id: P81894
names: Function
names: PTM
names: Similarity
messages: Belongs to the cytochrome c family.
messages: Binds 3 heme groups per subunit.
messages: May be involved in anaerobic iron respiration.

269799:GMET RS11620
gene id: 269799:GMET_RS11620
uniprot id: Q39T94
names: Function
messages: Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP.

269799:GMET RS18165
gene id: 269799:GMET_RS18165
uniprot id: Q39TL7
names: Similarity
messages: Belongs to the glycosyl hydrolase 32 family.

269799:GMET RS04465
gene id: 269799:GMET_RS04465
uniprot id: Q39X91
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

269799:GMET RS12290
gene id: 269799:GMET_RS12290
uniprot id: Q39SV8
names: Subcellular Location Annotation
messages: Membrane

269799:GMET RS07210
gene id: 269799:GMET_RS07210
uniprot id: Q39VR0
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

269799:GMET RS14735
gene id: 269799:GMET_RS14735
uniprot id: Q39RH1
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

269799:GMET RS08115
gene id: 269799:GMET_RS08115
uniprot id: Q39V78
names: Similarity
messages: Belongs to the archease family.

269799:GMET RS05970
gene id: 269799:GMET_RS05970
uniprot id: Q39WF1
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

269799:GMET RS00525
gene id: 269799:GMET_RS00525
uniprot id: Q39ZH1
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

269799:GMET RS00205
gene id: 269799:GMET_RS00205
uniprot id: Q39ZN3
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSP33 family.
messages: Cytoplasm
messages: Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.
messages: Under oxidizing conditions two disulfide bonds are formed involving the reactive cysteines. Under reducing conditions zinc is bound to the reactive cysteines and the protein is inactive.

269799:GMET RS17780
gene id: 269799:GMET_RS17780
uniprot id: Q39PS5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

269799:GMET RS08435
gene id: 269799:GMET_RS08435
uniprot id: Q39V17
names: Activity Regulation
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.

269799:GMET RS10435
gene id: 269799:GMET_RS10435
uniprot id: Q39TX7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

269799:GMET RS06670
gene id: 269799:GMET_RS06670
uniprot id: Q39W17
names: Similarity
messages: Belongs to the HicA mRNA interferase family.

269799:GMET RS02040
gene id: 269799:GMET_RS02040
uniprot id: Q39YM3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

269799:GMET RS00865
gene id: 269799:GMET_RS00865
uniprot id: Q39ZA5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

269799:GMET RS06795
gene id: 269799:GMET_RS06795
uniprot id: Q39VY9
names: Similarity
messages: Belongs to the P(II) protein family.

269799:GMET RS00080
gene id: 269799:GMET_RS00080
uniprot id: Q39ZQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.

269799:GMET RS07795
gene id: 269799:GMET_RS07795
uniprot id: Q39VE1
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

269799:GMET RS00070
gene id: 269799:GMET_RS00070
uniprot id: Q39ZR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

269799:GMET RS17850
gene id: 269799:GMET_RS17850
uniprot id: Q39PR1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.

269799:GMET RS15970
gene id: 269799:GMET_RS15970
uniprot id: Q39QS4
names: Similarity
messages: Belongs to the DNA polymerase type-B family.

269799:GMET RS13535
gene id: 269799:GMET_RS13535
uniprot id: Q39S56
names: Subcellular Location Annotation
messages: Membrane

269799:GMET RS04290
gene id: 269799:GMET_RS04290
uniprot id: Q39XC5
names: Similarity
messages: Belongs to the RecJ family.

269799:GMET RS04880
gene id: 269799:GMET_RS04880
uniprot id: Q39X07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial secretin family.
messages: Cell outer membrane

269799:GMET RS12265
gene id: 269799:GMET_RS12265
uniprot id: Q39SW3
names: Subcellular Location Annotation
messages: Membrane

269799:GMET RS08800
gene id: 269799:GMET_RS08800
uniprot id: Q39UU4
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

269799:GMET RS16725
gene id: 269799:GMET_RS16725
uniprot id: Q39QC4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

269799:GMET RS03105
gene id: 269799:GMET_RS03105
uniprot id: Q39Y16
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

269799:GMET RS16760
gene id: 269799:GMET_RS16760
uniprot id: Q39QB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 5 family.
messages: Membrane

269799:GMET RS02570
gene id: 269799:GMET_RS02570
uniprot id: Q39YB6
names: Subcellular Location Annotation
messages: Endosome membrane
messages: Membrane

269799:GMET RS03270
gene id: 269799:GMET_RS03270
uniprot id: Q39XY1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

269799:GMET RS12905
gene id: 269799:GMET_RS12905
uniprot id: Q39SI5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I fumarase family.
messages: Catalyzes the reversible hydration of fumarate to (S)-malate.
messages: Homodimer.

269799:GMET RS01485
gene id: 269799:GMET_RS01485
uniprot id: Q39YY3
names: Similarity
messages: Belongs to the cytochrome c-552 family.

269799:GMET RS17840
gene id: 269799:GMET_RS17840
uniprot id: Q39PR3
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

269799:GMET RS06685
gene id: 269799:GMET_RS06685
uniprot id: Q39W13
names: Subcellular Location Annotation
messages: Membrane

269799:GMET RS03765
gene id: 269799:GMET_RS03765
uniprot id: Q39XN1
names: Similarity
messages: Belongs to the peptidase S8 family.

269799:GMET RS09905
gene id: 269799:GMET_RS09905
uniprot id: Q39U84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Cell membrane
messages: Membrane

269799:GMET RS09255
gene id: 269799:GMET_RS09255
uniprot id: Q39UK7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

269799:GMET RS12315
gene id: 269799:GMET_RS12315
uniprot id: Q39SV3
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the carotenoid oxygenase family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Heterodimer of a large and a small subunit.

269799:GMET RS09210
gene id: 269799:GMET_RS09210
uniprot id: Q39UL6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

269799:GMET RS02190
gene id: 269799:GMET_RS02190
uniprot id: Q39YJ3
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

269799:GMET RS12720
gene id: 269799:GMET_RS12720
uniprot id: Q39SM2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. CmoB family.
messages: Catalyzes carboxymethyl transfer from carboxy-S-adenosyl-L-methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5-carboxymethoxyuridine (cmo5U) at position 34 in tRNAs.
messages: Homotetramer.

269799:GMET RS06465
gene id: 269799:GMET_RS06465
uniprot id: Q39W54
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

269799:GMET RS08905
gene id: 269799:GMET_RS08905
uniprot id: Q39US3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

269799:GMET RS16730
gene id: 269799:GMET_RS16730
uniprot id: Q39QC3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

269799:GMET RS05535
gene id: 269799:GMET_RS05535
uniprot id: Q39WN1
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family. GreB subfamily.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length.

269799:GMET RS07955
gene id: 269799:GMET_RS07955
uniprot id: Q39VB0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

269799:GMET RS03335
gene id: 269799:GMET_RS03335
uniprot id: Q39XW8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NifD/NifK/NifE/NifN family.
messages: Binds 1 [8Fe-7S] cluster per heterodimer.
messages: Tetramer of two alpha and two beta chains. Forms complex with the iron protein (nitrogenase component 2).
messages: This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation.

269799:GMET RS01035
gene id: 269799:GMET_RS01035
uniprot id: Q39Z72
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.

269799:GMET RS10530
gene id: 269799:GMET_RS10530
uniprot id: Q39TV7
names: Function
names: Induction
names: Similarity
names: Subunit
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: By benzoate.
messages: Homohexamer.
messages: Involved in the central benzoyl-CoA catabolism. Catalyzes the addition of one molecule of water to the double bond and the hydrolytic cleavage of C-C bond in the alicyclic ring, 6-oxocyclohex-1-ene-1-carbonyl-CoA (6-OCH-CoA) to yield 3-hydroxypimelyl-CoA.

269799:GMET RS12805
gene id: 269799:GMET_RS12805
uniprot id: Q39SK5
names: Similarity
messages: Belongs to the AAE transporter (TC 2.A.81) family.

269799:GMET RS10465
gene id: 269799:GMET_RS10465
uniprot id: Q39TX1
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

269799:GMET RS14320
gene id: 269799:GMET_RS14320
uniprot id: Q39RP8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.
messages: Cytoplasm

269799:GMET RS09865
gene id: 269799:GMET_RS09865
uniprot id: Q39U92
names: Similarity
messages: Belongs to the transglycosylase Slt family.

269799:GMET RS13465
gene id: 269799:GMET_RS13465
uniprot id: Q39S72
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
messages: Catalyzes the reversible phosphorylation of S-methyl-5'-thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.
messages: Homohexamer. Dimer of a homotrimer.

269799:GMET RS16230
gene id: 269799:GMET_RS16230
uniprot id: Q39QM2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-insensitive subfamily.
messages: Cell inner membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force.

269799:GMET RS09500
gene id: 269799:GMET_RS09500
uniprot id: Q39UG5
names: Similarity
messages: Belongs to the aspartokinase family.

269799:GMET RS09815
gene id: 269799:GMET_RS09815
uniprot id: Q39UA2
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

269799:GMET RS17235
gene id: 269799:GMET_RS17235
uniprot id: Q39Q25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1C family.
messages: Periplasm

269799:GMET RS09230
gene id: 269799:GMET_RS09230
uniprot id: Q39UL2
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

269799:GMET RS06345
gene id: 269799:GMET_RS06345
uniprot id: Q39W78
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

269799:GMET RS01865
gene id: 269799:GMET_RS01865
uniprot id: Q39YQ7
names: Subcellular Location Annotation
messages: Membrane

269799:GMET RS02225
gene id: 269799:GMET_RS02225
uniprot id: Q39YI6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliS family.
messages: cytosol

269799:GMET RS10345
gene id: 269799:GMET_RS10345
uniprot id: Q39TZ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

269799:GMET RS03370
gene id: 269799:GMET_RS03370
uniprot id: Q39XW1
names: Similarity
messages: Belongs to the NifX/NifY family.

269799:GMET RS15140
gene id: 269799:GMET_RS15140
uniprot id: Q39R90
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: May be specifically involved in the processing, transport, and/or maturation of the MADH beta-subunit.
messages: Membrane

269799:GMET RS15915
gene id: 269799:GMET_RS15915
uniprot id: Q39QT5
names: Cofactor
names: Similarity
messages: Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.
messages: Binds 1 zinc ion per subunit.

269799:GMET RS00885
gene id: 269799:GMET_RS00885
uniprot id: Q39ZA1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.
messages: Resistance to Hg(2+) in bacteria appears to be governed by a specialized system which includes mercuric reductase. MerA protein is responsible for volatilizing mercury as Hg(0).

269799:GMET RS01910
gene id: 269799:GMET_RS01910
uniprot id: Q39YP8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Lacks the C-terminal regulatory region which is replaced by HisZ.

269799:GMET RS05635
gene id: 269799:GMET_RS05635
uniprot id: Q39WL1
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

269799:GMET RS16035
gene id: 269799:GMET_RS16035
uniprot id: Q39QR1
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

269799:GMET RS03290
gene id: 269799:GMET_RS03290
uniprot id: Q39XX7
names: Subcellular Location Annotation
messages: Membrane

269799:GMET RS00015
gene id: 269799:GMET_RS00015
uniprot id: Q39ZS1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

269799:GMET RS06385
gene id: 269799:GMET_RS06385
uniprot id: Q39W70
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

269799:GMET RS13915
gene id: 269799:GMET_RS13915
uniprot id: Q39RY0
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

269799:GMET RS13150
gene id: 269799:GMET_RS13150
uniprot id: Q39SD5
names: Similarity
messages: Belongs to the 6-phosphogluconate dehydrogenase family.

269799:GMET RS11525
gene id: 269799:GMET_RS11525
uniprot id: Q39TB3
names: Function
names: Similarity
messages: Belongs to the FlgM family.
messages: Responsible for the coupling of flagellin expression to flagellar assembly by preventing expression of the flagellin genes when a component of the middle class of proteins is defective. It negatively regulates flagellar genes by inhibiting the activity of FliA by directly binding to FliA.

269799:GMET RS03520
gene id: 269799:GMET_RS03520
uniprot id: Q39XT1
names: Subcellular Location Annotation
messages: Membrane

269799:GMET RS14075
gene id: 269799:GMET_RS14075
uniprot id: Q39RU7
names: Subcellular Location Annotation
messages: Membrane

269799:GMET RS05340
gene id: 269799:GMET_RS05340
uniprot id: Q39WS0
names: Similarity
messages: In the N-terminal section; belongs to the CRISPR-associated nuclease Cas3-HD family.
messages: In the central section; belongs to the CRISPR-associated helicase Cas3 family.

269799:GMET RS00190
gene id: 269799:GMET_RS00190
uniprot id: Q39ZN6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAK/KUP transporter (TC 2.A.72) family.
messages: Cell inner membrane
messages: Transport of potassium into the cell. Likely operates as a K(+):H(+) symporter.

269799:GMET RS14555
gene id: 269799:GMET_RS14555
uniprot id: Q39RK6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmC/CycZ/HelC family.
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

269799:GMET RS01700
gene id: 269799:GMET_RS01700
uniprot id: Q39YU1
names: Subcellular Location Annotation
messages: Cytoplasm

269799:GMET RS03375
gene id: 269799:GMET_RS03375
uniprot id: Q39XW0
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

269799:GMET RS13645
gene id: 269799:GMET_RS13645
uniprot id: Q39S34
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

269799:GMET RS13880
gene id: 269799:GMET_RS13880
uniprot id: Q39RY7
names: Function
names: Similarity
messages: Belongs to the alpha-ketoglutarate dehydrogenase family.
messages: E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

269799:GMET RS06425
gene id: 269799:GMET_RS06425
uniprot id: Q39W62
names: Activity Regulation
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.

269799:GMET RS00790
gene id: 269799:GMET_RS00790
uniprot id: Q39ZC0
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

269799:GMET RS10850
gene id: 269799:GMET_RS10850
uniprot id: Q39TP2
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

269799:GMET RS01905
gene id: 269799:GMET_RS01905
uniprot id: Q39YP9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm

269799:GMET RS00020
gene id: 269799:GMET_RS00020
uniprot id: Q39ZS0
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

269799:GMET RS07135
gene id: 269799:GMET_RS07135
uniprot id: Q39VS4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

269799:GMET RS03435
gene id: 269799:GMET_RS03435
uniprot id: Q39XU8
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

269799:GMET RS08945
gene id: 269799:GMET_RS08945
uniprot id: Q39UR5
names: Function
names: Similarity
messages: Belongs to the nucleoside phosphorylase PpnP family.
messages: Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions.

269799:GMET RS13410
gene id: 269799:GMET_RS13410
uniprot id: Q39S83
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

269799:GMET RS03010
gene id: 269799:GMET_RS03010
uniprot id: Q39Y29
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

269799:GMET RS13610
gene id: 269799:GMET_RS13610
uniprot id: Q39S41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

269799:GMET RS16700
gene id: 269799:GMET_RS16700
uniprot id: Q39QC9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase small subunit family.
messages: Heterodimer of a large and a small subunit.
messages: Periplasm

269799:GMET RS16130
gene id: 269799:GMET_RS16130
uniprot id: Q39QP2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

269799:GMET RS05780
gene id: 269799:GMET_RS05780
uniprot id: Q39WI3
names: Subcellular Location Annotation
messages: Membrane

269799:GMET RS10495
gene id: 269799:GMET_RS10495
uniprot id: Q39TW5
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

269799:GMET RS05445
gene id: 269799:GMET_RS05445
uniprot id: Q39WP9
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

269799:GMET RS06895
gene id: 269799:GMET_RS06895
uniprot id: Q39VX1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA.
messages: Cytoplasm
messages: Homodimer.

269799:GMET RS07115
gene id: 269799:GMET_RS07115
uniprot id: Q39VS8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-3 family.
messages: Cytoplasm
messages: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
messages: Monomer.

269799:GMET RS14795
gene id: 269799:GMET_RS14795
uniprot id: Q39RF9
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

269799:GMET RS03475
gene id: 269799:GMET_RS03475
uniprot id: Q39XU0
names: Function
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.
messages: This protein is a Fe-Mo-cofactor biosynthetic component.

269799:GMET RS09780
gene id: 269799:GMET_RS09780
uniprot id: Q39UA9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

269799:GMET RS07125
gene id: 269799:GMET_RS07125
uniprot id: Q39VS6
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

269799:GMET RS09595
gene id: 269799:GMET_RS09595
uniprot id: Q39UE7
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Feedback inhibited by histidine.

269799:GMET RS11335
gene id: 269799:GMET_RS11335
uniprot id: Q39TE6
names: Subcellular Location Annotation
messages: Membrane

269799:GMET RS07350
gene id: 269799:GMET_RS07350
uniprot id: Q39VN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

269799:GMET RS09170
gene id: 269799:GMET_RS09170
uniprot id: Q39UM4
names: Subcellular Location Annotation
messages: Membrane

269799:GMET RS16355
gene id: 269799:GMET_RS16355
uniprot id: Q39QJ9
names: Similarity
messages: Belongs to the transglycosylase Slt family.

269799:GMET RS14575
gene id: 269799:GMET_RS14575
uniprot id: Q39RK2
names: Similarity
messages: Belongs to the GARS family.

269799:GMET RS07950
gene id: 269799:GMET_RS07950
uniprot id: Q39VB1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

269799:GMET RS17350
gene id: 269799:GMET_RS17350
uniprot id: Q39Q05
names: Subcellular Location Annotation
messages: Membrane

269799:GMET RS01870
gene id: 269799:GMET_RS01870
uniprot id: Q39YQ6
names: Subcellular Location Annotation
messages: Membrane

269799:GMET RS06625
gene id: 269799:GMET_RS06625
uniprot id: Q39W24
names: Similarity
messages: Belongs to the HepT RNase toxin family.

269799:GMET RS17580
gene id: 269799:GMET_RS17580
uniprot id: Q39PW2
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

269799:GMET RS12180
gene id: 269799:GMET_RS12180
uniprot id: Q39SY0
names: Function
names: Similarity
messages: Belongs to the CheD family.
messages: Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.

269799:GMET RS11740
gene id: 269799:GMET_RS11740
uniprot id: Q39T70
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

269799:GMET RS12075
gene id: 269799:GMET_RS12075
uniprot id: Q39T01
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

269799:GMET RS07975
gene id: 269799:GMET_RS07975
uniprot id: Q39VA6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

269799:GMET RS09540
gene id: 269799:GMET_RS09540
uniprot id: Q39UF7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the adenylate cyclase family. DacA/CdaA subfamily.
messages: Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably a homodimer.

269799:GMET RS04175
gene id: 269799:GMET_RS04175
uniprot id: Q39XE8
names: Similarity
messages: Belongs to the hemerythrin family.

269799:GMET RS14755
gene id: 269799:GMET_RS14755
uniprot id: Q39RG7
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

269799:GMET RS15385
gene id: 269799:GMET_RS15385
uniprot id: Q39R40
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Homodimer.

269799:GMET RS08175
gene id: 269799:GMET_RS08175
uniprot id: Q39V66
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

269799:GMET RS04315
gene id: 269799:GMET_RS04315
uniprot id: Q39XC0
names: Function
names: Subcellular Location Annotation
messages: Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.
messages: Cytoplasm

269799:GMET RS12085
gene id: 269799:GMET_RS12085
uniprot id: Q39SZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell inner membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Membrane

269799:GMET RS11540
gene id: 269799:GMET_RS11540
uniprot id: Q39TB0
names: Similarity
messages: Belongs to the AOR/FOR family.

269799:GMET RS16195
gene id: 269799:GMET_RS16195
uniprot id: Q39QM9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmC/CycZ/HelC family.
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

269799:GMET RS15405
gene id: 269799:GMET_RS15405
uniprot id: Q39R36
names: Function
names: Similarity
messages: Belongs to the GTP cyclohydrolase IV family.
messages: Converts GTP to 7,8-dihydroneopterin triphosphate.

269799:GMET RS11725
gene id: 269799:GMET_RS11725
uniprot id: Q39T73
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

269799:GMET RS05030
gene id: 269799:GMET_RS05030
uniprot id: Q39WX6
names: Cofactor
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

269799:GMET RS05825
gene id: 269799:GMET_RS05825
uniprot id: Q39WH4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

269799:GMET RS05505
gene id: 269799:GMET_RS05505
uniprot id: Q39WN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

269799:GMET RS05610
gene id: 269799:GMET_RS05610
uniprot id: Q39WL7
names: Similarity
messages: Belongs to the transposase IS21/IS408/IS1162 family.

269799:GMET RS17710
gene id: 269799:GMET_RS17710
uniprot id: Q39PT9
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

269799:GMET RS08650
gene id: 269799:GMET_RS08650
uniprot id: Q39UX4
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

269799:GMET RS05895
gene id: 269799:GMET_RS05895
uniprot id: Q39WG0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell inner membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

269799:GMET RS12000
gene id: 269799:GMET_RS12000
uniprot id: Q39T18
names: Subcellular Location Annotation
messages: Membrane

269799:GMET RS07020
gene id: 269799:GMET_RS07020
uniprot id: Q39VU6
names: Similarity
messages: Belongs to the GSP E family.

269799:GMET RS02070
gene id: 269799:GMET_RS02070
uniprot id: Q39YL7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

269799:GMET RS17090
gene id: 269799:GMET_RS17090
uniprot id: Q39Q53
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase delta chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

269799:GMET RS02285
gene id: 269799:GMET_RS02285
uniprot id: Q39YH4
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

269799:GMET RS16935
gene id: 269799:GMET_RS16935
uniprot id: Q39Q83
names: Function
names: Similarity
messages: Belongs to the RlpA family.
messages: Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.

269799:GMET RS01950
gene id: 269799:GMET_RS01950
uniprot id: Q39YP0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

269799:GMET RS06270
gene id: 269799:GMET_RS06270
uniprot id: Q39W93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

269799:GMET RS03320
gene id: 269799:GMET_RS03320
uniprot id: Q39XX1
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

269799:GMET RS09385
gene id: 269799:GMET_RS09385
uniprot id: Q39UI1
names: Similarity
messages: Belongs to the GSP E family.

269799:GMET RS01160
gene id: 269799:GMET_RS01160
uniprot id: Q39Z49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

269799:GMET RS16750
gene id: 269799:GMET_RS16750
uniprot id: Q39QC0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell inner membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

269799:GMET RS11670
gene id: 269799:GMET_RS11670
uniprot id: Q39T84
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell inner membrane
messages: Cytoplasm
messages: Monomer.

269799:GMET RS02015
gene id: 269799:GMET_RS02015
uniprot id: Q39YM8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

269799:GMET RS10030
gene id: 269799:GMET_RS10030
uniprot id: Q39U59
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

269799:GMET RS08180
gene id: 269799:GMET_RS08180
uniprot id: Q39V65
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

269799:GMET RS10430
gene id: 269799:GMET_RS10430
uniprot id: Q39TX8
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

269799:GMET RS07870
gene id: 269799:GMET_RS07870
uniprot id: Q39VC6
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

269799:GMET RS09750
gene id: 269799:GMET_RS09750
uniprot id: Q39UB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell inner membrane
messages: Membrane

269799:GMET RS10840
gene id: 269799:GMET_RS10840
uniprot id: Q39TP4
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

269799:GMET RS16950
gene id: 269799:GMET_RS16950
uniprot id: Q39Q80
names: Subcellular Location Annotation
messages: Membrane

269799:GMET RS14820
gene id: 269799:GMET_RS14820
uniprot id: Q39RF4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HemG family.
messages: Binds 1 FMN non-covalently per subunit.
messages: Catalyzes the 6-electron oxidation of protoporphyrinogen IX to form protoporphyrin IX; under anaerobic conditions uses menaquinone as an electron acceptor, under aerobic conditions uses ubiquinone as an electron acceptor.
messages: Cell inner membrane

269799:GMET RS11075
gene id: 269799:GMET_RS11075
uniprot id: Q39TJ8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

269799:GMET RS16775
gene id: 269799:GMET_RS16775
uniprot id: Q39QB5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

269799:GMET RS02860
gene id: 269799:GMET_RS02860
uniprot id: Q39Y58
names: Subcellular Location Annotation
messages: Membrane

269799:GMET RS06350
gene id: 269799:GMET_RS06350
uniprot id: Q39W77
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

269799:GMET RS13695
gene id: 269799:GMET_RS13695
uniprot id: Q39S24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

269799:GMET RS02325
gene id: 269799:GMET_RS02325
uniprot id: Q39YG6
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

269799:GMET RS01235
gene id: 269799:GMET_RS01235
uniprot id: Q39Z33
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response.
messages: Belongs to the SrkA/RdoA protein kinase family.
messages: Cytoplasm
messages: Monomer.

269799:GMET RS04075
gene id: 269799:GMET_RS04075
uniprot id: Q39XG8
names: Similarity
messages: Belongs to the band 7/mec-2 family.

269799:GMET RS16860
gene id: 269799:GMET_RS16860
uniprot id: Q39Q98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial secretin family. GSP D subfamily.
messages: Cell outer membrane

269799:GMET RS15840
gene id: 269799:GMET_RS15840
uniprot id: Q39QV0
names: Similarity
messages: Belongs to the type III secretion exporter family.

269799:GMET RS08355
gene id: 269799:GMET_RS08355
uniprot id: Q39V32
names: Similarity
messages: Belongs to the MbcT/ParT/Res family.

269799:GMET RS02645
gene id: 269799:GMET_RS02645
uniprot id: Q39YA1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

269799:GMET RS16805
gene id: 269799:GMET_RS16805
uniprot id: Q39QA9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 30 kDa subunit family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

269799:GMET RS00810
gene id: 269799:GMET_RS00810
uniprot id: Q39ZB6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

269799:GMET RS08000
gene id: 269799:GMET_RS08000
uniprot id: Q39VA1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

269799:GMET RS13855
gene id: 269799:GMET_RS13855
uniprot id: Q39RZ2
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

269799:GMET RS17205
gene id: 269799:GMET_RS17205
uniprot id: Q39Q31
names: Cofactor
names: Similarity
messages: Belongs to the PyrK family.
messages: Binds 1 [2Fe-2S] cluster per subunit.

269799:GMET RS15685
gene id: 269799:GMET_RS15685
uniprot id: Q39QY1
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

269799:GMET RS07015
gene id: 269799:GMET_RS07015
uniprot id: Q39VU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP E family.
messages: Cytoplasm

269799:GMET RS13475
gene id: 269799:GMET_RS13475
uniprot id: Q39S70
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

269799:GMET RS00820
gene id: 269799:GMET_RS00820
uniprot id: Q39ZB4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

269799:GMET RS06420
gene id: 269799:GMET_RS06420
uniprot id: Q39W63
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
messages: Belongs to the KdsB family.
messages: Cytoplasm

269799:GMET RS07680
gene id: 269799:GMET_RS07680
uniprot id: Q39VG5
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

269799:GMET RS05440
gene id: 269799:GMET_RS05440
uniprot id: Q39WQ0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

269799:GMET RS08135
gene id: 269799:GMET_RS08135
uniprot id: Q39V74
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.
messages: Monomer.

269799:GMET RS00040
gene id: 269799:GMET_RS00040
uniprot id: Q39ZR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

269799:GMET RS11140
gene id: 269799:GMET_RS11140
uniprot id: Q39TI5
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

269799:GMET RS14470
gene id: 269799:GMET_RS14470
uniprot id: Q39WR5
names: Function
names: Similarity
messages: Belongs to the transposase 11 family.
messages: Involved in the transposition of the insertion sequence IS5.

269799:GMET RS15920
gene id: 269799:GMET_RS15920
uniprot id: Q39QT4
names: Similarity
messages: Belongs to the glycosyl hydrolase 57 family.

269799:GMET RS14235
gene id: 269799:GMET_RS14235
uniprot id: Q39RR5
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

269799:GMET RS16660
gene id: 269799:GMET_RS16660
uniprot id: Q39QD7
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

269799:GMET RS01645
gene id: 269799:GMET_RS01645
uniprot id: Q39YV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
messages: Cell membrane
messages: Membrane

269799:GMET RS07730
gene id: 269799:GMET_RS07730
uniprot id: Q39VF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OmpP1/FadL family.
messages: Cell outer membrane
messages: Membrane

269799:GMET RS13705
gene id: 269799:GMET_RS13705
uniprot id: Q39S22
names: Similarity
messages: Belongs to the radical SAM superfamily. NifB family.

269799:GMET RS06515
gene id: 269799:GMET_RS06515
uniprot id: Q39W44
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

269799:GMET RS16540
gene id: 269799:GMET_RS16540
uniprot id: Q39QG1
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

269799:GMET RS16550
gene id: 269799:GMET_RS16550
uniprot id: Q39QF9
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

269799:GMET RS00550
gene id: 269799:GMET_RS00550
uniprot id: Q39ZG6
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

269799:GMET RS11680
gene id: 269799:GMET_RS11680
uniprot id: Q39T82
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

269799:GMET RS17520
gene id: 269799:GMET_RS17520
uniprot id: Q39PX5
names: Subcellular Location Annotation
messages: Cytoplasm

269799:GMET RS13400
gene id: 269799:GMET_RS13400
uniprot id: Q39S85
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family.

269799:GMET RS00935
gene id: 269799:GMET_RS00935
uniprot id: Q39Z92
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

269799:GMET RS00690
gene id: 269799:GMET_RS00690
uniprot id: Q39ZD8
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

269799:GMET RS00025
gene id: 269799:GMET_RS00025
uniprot id: Q39ZR9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

269799:GMET RS00595
gene id: 269799:GMET_RS00595
uniprot id: Q39ZF7
names: Similarity
messages: Belongs to the HupF/HypC family.

269799:GMET RS14245
gene id: 269799:GMET_RS14245
uniprot id: Q39RR3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

269799:GMET RS03745
gene id: 269799:GMET_RS03745
uniprot id: Q39XN5
names: Similarity
messages: Belongs to the DnaA family.

269799:GMET RS16735
gene id: 269799:GMET_RS16735
uniprot id: Q39QC2
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

269799:GMET RS02290
gene id: 269799:GMET_RS02290
uniprot id: Q39YH3
names: Similarity
messages: Belongs to the polysaccharide synthase family.

269799:GMET RS16375
gene id: 269799:GMET_RS16375
uniprot id: Q39QJ4
names: Function
messages: Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP.

269799:GMET RS06065
gene id: 269799:GMET_RS06065
uniprot id: Q39WD2
names: Subcellular Location Annotation
messages: Membrane

269799:GMET RS11850
gene id: 269799:GMET_RS11850
uniprot id: Q39T48
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

269799:GMET RS02845
gene id: 269799:GMET_RS02845
uniprot id: Q39Y61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0394 family.
messages: Membrane

269799:GMET RS01765
gene id: 269799:GMET_RS01765
uniprot id: Q39YS7
names: Similarity
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.
messages: Membrane

269799:GMET RS01290
gene id: 269799:GMET_RS01290
uniprot id: Q39Z22
names: Subcellular Location Annotation
messages: Membrane

269799:GMET RS15555
gene id: 269799:GMET_RS15555
uniprot id: Q39R07
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

269799:GMET RS15600
gene id: 269799:GMET_RS15600
uniprot id: Q39QZ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliF family.
messages: Membrane
messages: The M ring may be actively involved in energy transduction.

269799:GMET RS02480
gene id: 269799:GMET_RS02480
uniprot id: Q39YD4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 3B subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

269799:GMET RS12750
gene id: 269799:GMET_RS12750
uniprot id: Q39WL7
names: Similarity
messages: Belongs to the transposase IS21/IS408/IS1162 family.

269799:GMET RS05840
gene id: 269799:GMET_RS05840
uniprot id: Q39WH1
names: Subcellular Location Annotation
messages: Cytoplasm

269799:GMET RS04010
gene id: 269799:GMET_RS04010
uniprot id: Q39XI1
names: Similarity
messages: Belongs to the YjdM family.

269799:GMET RS02035
gene id: 269799:GMET_RS02035
uniprot id: Q39YM4
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm

269799:GMET RS06095
gene id: 269799:GMET_RS06095
uniprot id: Q39WC6
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

269799:GMET RS10255
gene id: 269799:GMET_RS10255
uniprot id: Q39U14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

269799:GMET RS08250
gene id: 269799:GMET_RS08250
uniprot id: Q39V51
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

269799:GMET RS03285
gene id: 269799:GMET_RS03285
uniprot id: Q39XX8
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

269799:GMET RS15545
gene id: 269799:GMET_RS15545
uniprot id: Q39R09
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell inner membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

269799:GMET RS09190
gene id: 269799:GMET_RS09190
uniprot id: Q39UM0
names: Function
names: Similarity
messages: Belongs to the phenylacetyl-CoA ligase family.
messages: Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).

269799:GMET RS09075
gene id: 269799:GMET_RS09075
uniprot id: Q39UP3
names: Similarity
messages: Belongs to the AOR/FOR family.

269799:GMET RS06360
gene id: 269799:GMET_RS06360
uniprot id: Q39W75
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain.

269799:GMET RS00095
gene id: 269799:GMET_RS00095
uniprot id: Q39ZQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Cytoplasm

269799:GMET RS06905
gene id: 269799:GMET_RS06905
uniprot id: Q39VW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

269799:GMET RS00680
gene id: 269799:GMET_RS00680
uniprot id: Q39ZE0
names: Similarity
messages: Belongs to the phosphohexose mutase family.

269799:GMET RS16795
gene id: 269799:GMET_RS16795
uniprot id: Q39QB1
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

269799:GMET RS03740
gene id: 269799:GMET_RS03740
uniprot id: Q39XN6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvB family.
messages: Forms a complex with RuvA.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.

269799:GMET RS02450
gene id: 269799:GMET_RS02450
uniprot id: Q39YE0
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

269799:GMET RS01065
gene id: 269799:GMET_RS01065
uniprot id: Q39Z66
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

269799:GMET RS11960
gene id: 269799:GMET_RS11960
uniprot id: Q39T26
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

269799:GMET RS06120
gene id: 269799:GMET_RS06120
uniprot id: Q39WC1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

269799:GMET RS14580
gene id: 269799:GMET_RS14580
uniprot id: Q39RK1
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

269799:GMET RS06955
gene id: 269799:GMET_RS06955
uniprot id: Q39VV9
names: Subcellular Location Annotation
messages: Membrane

269799:GMET RS00325
gene id: 269799:GMET_RS00325
uniprot id: Q39ZL0
names: Subcellular Location Annotation
messages: Membrane

269799:GMET RS06225
gene id: 269799:GMET_RS06225
uniprot id: Q39WA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

269799:GMET RS15200
gene id: 269799:GMET_RS15200
uniprot id: Q39R78
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

269799:GMET RS14375
gene id: 269799:GMET_RS14375
uniprot id: Q39RP2
names: Similarity
messages: Belongs to the UPF0102 family.

269799:GMET RS16045
gene id: 269799:GMET_RS16045
uniprot id: Q39QQ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

269799:GMET RS16450
gene id: 269799:GMET_RS16450
uniprot id: Q39WL7
names: Similarity
messages: Belongs to the transposase IS21/IS408/IS1162 family.

269799:GMET RS13870
gene id: 269799:GMET_RS13870
uniprot id: Q39RY9
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

269799:GMET RS15260
gene id: 269799:GMET_RS15260
uniprot id: Q39R66
names: Similarity
messages: Belongs to the DEAD box helicase family.

269799:GMET RS10365
gene id: 269799:GMET_RS10365
uniprot id: Q39TZ1
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

269799:GMET RS10195
gene id: 269799:GMET_RS10195
uniprot id: Q39U26
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

269799:GMET RS00365
gene id: 269799:GMET_RS00365
uniprot id: Q39ZK2
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

269799:GMET RS16520
gene id: 269799:GMET_RS16520
uniprot id: Q39QG5
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit A family.

269799:GMET RS16105
gene id: 269799:GMET_RS16105
uniprot id: Q39QP7
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

269799:GMET RS07580
gene id: 269799:GMET_RS07580
uniprot id: Q39VI5
names: Subcellular Location Annotation
messages: Membrane

269799:GMET RS01115
gene id: 269799:GMET_RS01115
uniprot id: Q39Z56
names: Caution
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

269799:GMET RS17545
gene id: 269799:GMET_RS17545
uniprot id: Q39PX0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Pal lipoprotein family.
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

269799:GMET RS05805
gene id: 269799:GMET_RS05805
uniprot id: Q39WH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

269799:GMET RS01970
gene id: 269799:GMET_RS01970
uniprot id: Q39YN6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

269799:GMET RS03035
gene id: 269799:GMET_RS03035
uniprot id: Q39Y24
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

269799:GMET RS02155
gene id: 269799:GMET_RS02155
uniprot id: Q39YK0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

269799:GMET RS16800
gene id: 269799:GMET_RS16800
uniprot id: Q39QB0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

269799:GMET RS12895
gene id: 269799:GMET_RS12895
uniprot id: Q39SI7
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins.

269799:GMET RS10220
gene id: 269799:GMET_RS10220
uniprot id: Q39U21
names: Similarity
messages: Belongs to the asparagine synthetase family.

269799:GMET RS10995
gene id: 269799:GMET_RS10995
uniprot id: Q39TL4
names: Subcellular Location Annotation
messages: Membrane

269799:GMET RS06680
gene id: 269799:GMET_RS06680
uniprot id: Q39W14
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

269799:GMET RS13135
gene id: 269799:GMET_RS13135
uniprot id: Q39SD8
names: Similarity
messages: Belongs to the barstar family.

269799:GMET RS05405
gene id: 269799:GMET_RS05405
uniprot id: Q39WQ7
names: Function
messages: Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP.

269799:GMET RS08085
gene id: 269799:GMET_RS08085
uniprot id: Q39V84
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

269799:GMET RS12460
gene id: 269799:GMET_RS12460
uniprot id: Q39SS4
names: Function
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.
messages: Functions in two distinct reactions of the de novo folate biosynthetic pathway. Catalyzes the addition of a glutamate residue to dihydropteroate (7,8-dihydropteroate or H2Pte) to form dihydrofolate (7,8-dihydrofolate monoglutamate or H2Pte-Glu). Also catalyzes successive additions of L-glutamate to tetrahydrofolate or 10-formyltetrahydrofolate or 5,10-methylenetetrahydrofolate, leading to folylpolyglutamate derivatives.

269799:GMET RS01610
gene id: 269799:GMET_RS01610
uniprot id: Q39WL7
names: Similarity
messages: Belongs to the transposase IS21/IS408/IS1162 family.

269799:GMET RS12680
gene id: 269799:GMET_RS12680
uniprot id: Q39SN0
names: Function
names: Subunit
messages: Binds the second messenger bis-(3'-5') cyclic dimeric guanosine monophosphate (c-di-GMP). Can bind two c-di-GMP molecules per monomer. May play a role in bacterial second-messenger regulated processes. Binding to c-di-GMP induces a conformational change of the C- and N-termini resulting in the exposure of a highly negative surface on one side of the protein to a possible effector protein.
messages: Monomer in both c-di-GMP-bound and free forms.

269799:GMET RS01355
gene id: 269799:GMET_RS01355
uniprot id: Q39Z09
names: Similarity
names: Subunit
messages: Belongs to the threonine aldolase family.
messages: Homotetramer.

269799:GMET RS10565
gene id: 269799:GMET_RS10565
uniprot id: Q39TV0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

269799:GMET RS03550
gene id: 269799:GMET_RS03550
uniprot id: Q39XS5
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
messages: Synthesizes alpha-1,4-glucan chains using ADP-glucose.

269799:GMET RS15495
gene id: 269799:GMET_RS15495
uniprot id: Q39R19
names: Cofactor
names: PTM
names: Subcellular Location Annotation
messages: Binds 2 heme groups per subunit.
messages: Binds 2 heme groups.
messages: Periplasm

269799:GMET RS14050
gene id: 269799:GMET_RS14050
uniprot id: Q39RV2
names: Similarity
messages: Belongs to the LOG family.

269799:GMET RS13510
gene id: 269799:GMET_RS13510
uniprot id: Q39S61
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

269799:GMET RS10795
gene id: 269799:GMET_RS10795
uniprot id: Q39TQ3
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

269799:GMET RS03075
gene id: 269799:GMET_RS03075
uniprot id: Q39Y08
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

269799:GMET RS04935
gene id: 269799:GMET_RS04935
uniprot id: Q39WZ6
names: Function
names: Similarity
messages: Belongs to the MqnA/MqnD family. MqnA subfamily.
messages: Catalyzes the dehydration of chorismate into 3-[(1-carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2).

269799:GMET RS16505
gene id: 269799:GMET_RS16505
uniprot id: Q39QG8
names: Similarity
messages: Belongs to the HMG-CoA lyase family.

269799:GMET RS03855
gene id: 269799:GMET_RS03855
uniprot id: Q39XL2
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

269799:GMET RS08745
gene id: 269799:GMET_RS08745
uniprot id: Q39UV5
names: Subcellular Location Annotation
messages: Membrane

269799:GMET RS17630
gene id: 269799:GMET_RS17630
uniprot id: Q39PV2
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.

269799:GMET RS09900
gene id: 269799:GMET_RS09900
uniprot id: Q39U85
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

269799:GMET RS13550
gene id: 269799:GMET_RS13550
uniprot id: Q39S53
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

269799:GMET RS14140
gene id: 269799:GMET_RS14140
uniprot id: Q39RT4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

269799:GMET RS15220
gene id: 269799:GMET_RS15220
uniprot id: Q39R74
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. RhlB subfamily.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in RNA degradation. Has RNA-dependent ATPase activity and unwinds double-stranded RNA.

269799:GMET RS03190
gene id: 269799:GMET_RS03190
uniprot id: Q39XZ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

269799:GMET RS16510
gene id: 269799:GMET_RS16510
uniprot id: Q39QG7
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

269799:GMET RS11580
gene id: 269799:GMET_RS11580
uniprot id: Q39TA2
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

269799:GMET RS07910
gene id: 269799:GMET_RS07910
uniprot id: Q39VB9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Cob(I)alamin adenosyltransferase family.
messages: Cytoplasm
messages: Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids.

269799:GMET RS16000
gene id: 269799:GMET_RS16000
uniprot id: Q39QR8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Homodimer.
messages: Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate.

269799:GMET RS08625
gene id: 269799:GMET_RS08625
uniprot id: Q39UX9
names: Subcellular Location Annotation
messages: Membrane

269799:GMET RS08440
gene id: 269799:GMET_RS08440
uniprot id: Q39V16
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

269799:GMET RS08730
gene id: 269799:GMET_RS08730
uniprot id: Q39UV8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA gyrase inhibitor YacG family.
messages: Binds 1 zinc ion.
messages: Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.
messages: Interacts with GyrB.

269799:GMET RS06310
gene id: 269799:GMET_RS06310
uniprot id: Q39W85
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

269799:GMET RS08150
gene id: 269799:GMET_RS08150
uniprot id: Q39V71
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

269799:GMET RS05320
gene id: 269799:GMET_RS05320
uniprot id: Q39WS4
names: Cofactor
messages: Binds 4 [4Fe-4S] clusters per subunit.

269799:GMET RS12405
gene id: 269799:GMET_RS12405
uniprot id: Q39ST5
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.

269799:GMET RS10620
gene id: 269799:GMET_RS10620
uniprot id: Q39TT9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetokinase family.
messages: Cytoplasm

269799:GMET RS05910
gene id: 269799:GMET_RS05910
uniprot id: Q39WF7
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

269799:GMET RS02360
gene id: 269799:GMET_RS02360
uniprot id: Q39YF9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CbiM family.
messages: Cell inner membrane
messages: Forms an energy-coupling factor (ECF) transporter complex composed of an ATP-binding protein (A component, CbiO), a transmembrane protein (T component, CbiQ) and 2 possible substrate-capture proteins (S components, CbiM and CbiN) of unknown stoichimetry.
messages: Membrane
messages: Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import.

269799:GMET RS14705
gene id: 269799:GMET_RS14705
uniprot id: Q39RH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HupC/HyaC/HydC family.
messages: Membrane

269799:GMET RS11390
gene id: 269799:GMET_RS11390
uniprot id: Q39TD8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

269799:GMET RS05185
gene id: 269799:GMET_RS05185
uniprot id: Q39WU8
names: Function
names: Similarity
messages: Belongs to the MoaB/Mog family.
messages: May be involved in the biosynthesis of molybdopterin.

269799:GMET RS15625
gene id: 269799:GMET_RS15625
uniprot id: Q39QZ3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

269799:GMET RS17105
gene id: 269799:GMET_RS17105
uniprot id: Q39Q50
names: Function
names: Similarity
messages: Belongs to the ParB family.
messages: Involved in chromosome partition. Localize to both poles of the predivisional cell following completion of DNA replication. Binds to the DNA origin of replication.

269799:GMET RS16845
gene id: 269799:GMET_RS16845
uniprot id: Q39QA1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

269799:GMET RS15700
gene id: 269799:GMET_RS15700
uniprot id: Q39QX8
names: Similarity
messages: Belongs to the UPF0111 family.

269799:GMET RS12555
gene id: 269799:GMET_RS12555
uniprot id: Q39SQ6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.

269799:GMET RS03360
gene id: 269799:GMET_RS03360
uniprot id: Q39XW3
names: Function
names: Similarity
messages: Belongs to the NifD/NifK/NifE/NifN family.
messages: This protein may play a role in the biosynthesis of the prosthetic group of nitrogenase (FeMo cofactor).

269799:GMET RS11555
gene id: 269799:GMET_RS11555
uniprot id: Q39TA7
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

269799:GMET RS00195
gene id: 269799:GMET_RS00195
uniprot id: Q39ZN5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAK/KUP transporter (TC 2.A.72) family.
messages: Cell inner membrane
messages: Transport of potassium into the cell. Likely operates as a K(+):H(+) symporter.

269799:GMET RS08335
gene id: 269799:GMET_RS08335
uniprot id: Q39V36
names: Cofactor
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.

269799:GMET RS12125
gene id: 269799:GMET_RS12125
uniprot id: Q39SZ1
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

269799:GMET RS15130
gene id: 269799:GMET_RS15130
uniprot id: Q39R92
names: Similarity
messages: Belongs to the UPF0166 family.

269799:GMET RS13905
gene id: 269799:GMET_RS13905
uniprot id: Q39RY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

269799:GMET RS10390
gene id: 269799:GMET_RS10390
uniprot id: Q39TY6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

269799:GMET RS17385
gene id: 269799:GMET_RS17385
uniprot id: Q39PZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 13 family.
messages: Cytoplasm

269799:GMET RS09505
gene id: 269799:GMET_RS09505
uniprot id: Q39UG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

269799:GMET RS02375
gene id: 269799:GMET_RS02375
uniprot id: Q39YF6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Part of an ABC transporter complex. Responsible for energy coupling to the transport system.

269799:GMET RS11255
gene id: 269799:GMET_RS11255
uniprot id: Q39TG2
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

269799:GMET RS03180
gene id: 269799:GMET_RS03180
uniprot id: Q39Y01
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity).

269799:GMET RS14250
gene id: 269799:GMET_RS14250
uniprot id: Q39RR2
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

269799:GMET RS01070
gene id: 269799:GMET_RS01070
uniprot id: Q39Z65
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. LL-diaminopimelate aminotransferase subfamily.
messages: Homodimer.
messages: Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate.

269799:GMET RS02025
gene id: 269799:GMET_RS02025
uniprot id: Q39YM6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsL family.
messages: Cell inner membrane
messages: Essential cell division protein.
messages: Membrane

269799:GMET RS04820
gene id: 269799:GMET_RS04820
uniprot id: Q39X19
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

269799:GMET RS17125
gene id: 269799:GMET_RS17125
uniprot id: Q39Q46
names: Subcellular Location Annotation
messages: Membrane

269799:GMET RS03275
gene id: 269799:GMET_RS03275
uniprot id: Q39XY0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

269799:GMET RS14290
gene id: 269799:GMET_RS14290
uniprot id: Q39RQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

269799:GMET RS09730
gene id: 269799:GMET_RS09730
uniprot id: Q39UB9
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

269799:GMET RS14595
gene id: 269799:GMET_RS14595
uniprot id: Q39RJ8
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

269799:GMET RS00380
gene id: 269799:GMET_RS00380
uniprot id: Q39ZJ9
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

269799:GMET RS12185
gene id: 269799:GMET_RS12185
uniprot id: Q39SX9
names: Function
messages: Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP.

269799:GMET RS04520
gene id: 269799:GMET_RS04520
uniprot id: Q39X79
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. NspC subfamily.
messages: Catalyzes the decarboxylation of carboxynorspermidine and carboxyspermidine.
messages: Cytoplasm
messages: Homodimer.

269799:GMET RS10615
gene id: 269799:GMET_RS10615
uniprot id: Q39TU0
names: Caution
names: Function
names: Similarity
messages: Belongs to the UbiX/PAD1 family.
messages: Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

269799:GMET RS04710
gene id: 269799:GMET_RS04710
uniprot id: Q39X41
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.

269799:GMET RS16895
gene id: 269799:GMET_RS16895
uniprot id: Q39Q91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP K family.
messages: Cell inner membrane
messages: Membrane

269799:GMET RS00355
gene id: 269799:GMET_RS00355
uniprot id: Q39ZK4
names: Function
names: Similarity
messages: Belongs to the GlnE family.
messages: Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell.

269799:GMET RS08035
gene id: 269799:GMET_RS08035
uniprot id: Q39V94
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

269799:GMET RS13895
gene id: 269799:GMET_RS13895
uniprot id: Q39RY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

269799:GMET RS16790
gene id: 269799:GMET_RS16790
uniprot id: Q39QB2
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

269799:GMET RS16835
gene id: 269799:GMET_RS16835
uniprot id: Q39QA3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase A chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.

269799:GMET RS02165
gene id: 269799:GMET_RS02165
uniprot id: Q39YJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgH family.
messages: Cell outer membrane
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

269799:GMET RS12255
gene id: 269799:GMET_RS12255
uniprot id: Q39SW5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.
messages: Cell inner membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system and for the release of the potassium ions to the cytoplasm.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

269799:GMET RS04475
gene id: 269799:GMET_RS04475
uniprot id: Q39X89
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmG family. TrmFO subfamily.
messages: Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
messages: Cytoplasm

269799:GMET RS01940
gene id: 269799:GMET_RS01940
uniprot id: Q39YP2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

269799:GMET RS09155
gene id: 269799:GMET_RS09155
uniprot id: Q39UM7
names: Function
names: Similarity
messages: Belongs to the phenylacetyl-CoA ligase family.
messages: Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).

269799:GMET RS10385
gene id: 269799:GMET_RS10385
uniprot id: Q39TY7
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

269799:GMET RS16720
gene id: 269799:GMET_RS16720
uniprot id: Q39QC5
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TtcA family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is chelated by three Cys residues, the fourth Fe has a free coordination site that may bind a sulfur atom transferred from the persulfide of IscS.
messages: Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.
messages: Cytoplasm
messages: Homodimer.
messages: The thiolation reaction likely consists of two steps: a first activation step by ATP to form an adenylated intermediate of the target base of tRNA, and a second nucleophilic substitution step of the sulfur (S) atom supplied by the hydrosulfide attached to the Fe-S cluster.

269799:GMET RS05580
gene id: 269799:GMET_RS05580
uniprot id: Q39WM2
names: Subcellular Location Annotation
messages: Periplasm

269799:GMET RS17435
gene id: 269799:GMET_RS17435
uniprot id: Q39PY8
names: Subcellular Location Annotation
messages: Membrane

269799:GMET RS01270
gene id: 269799:GMET_RS01270
uniprot id: Q39Z26
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell inner membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.

269799:GMET RS01975
gene id: 269799:GMET_RS01975
uniprot id: Q39YN5
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

269799:GMET RS08185
gene id: 269799:GMET_RS08185
uniprot id: Q39V64
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

269799:GMET RS16185
gene id: 269799:GMET_RS16185
uniprot id: Q39QN1
names: Similarity
messages: Belongs to the thioredoxin family.

269799:GMET RS00605
gene id: 269799:GMET_RS00605
uniprot id: Q39ZF5
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. HypB/HupM subfamily.

269799:GMET RS06985
gene id: 269799:GMET_RS06985
uniprot id: Q39VV3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

269799:GMET RS01805
gene id: 269799:GMET_RS01805
uniprot id: Q39YR9
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

269799:GMET RS16495
gene id: 269799:GMET_RS16495
uniprot id: Q39QH0
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

269799:GMET RS09480
gene id: 269799:GMET_RS09480
uniprot id: Q39UG9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

269799:GMET RS11450
gene id: 269799:GMET_RS11450
uniprot id: Q39WL7
names: Similarity
messages: Belongs to the transposase IS21/IS408/IS1162 family.

269799:GMET RS00215
gene id: 269799:GMET_RS00215
uniprot id: Q39ZN1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

269799:GMET RS03095
gene id: 269799:GMET_RS03095
uniprot id: Q39Y18
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

269799:GMET RS13800
gene id: 269799:GMET_RS13800
uniprot id: Q39S03
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.

269799:GMET RS10035
gene id: 269799:GMET_RS10035
uniprot id: Q39U58
names: Function
names: Similarity
messages: Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor.
messages: Belongs to the biotin--protein ligase family.

269799:GMET RS11840
gene id: 269799:GMET_RS11840
uniprot id: Q39T50
names: Subcellular Location Annotation
messages: Membrane

269799:GMET RS05915
gene id: 269799:GMET_RS05915
uniprot id: Q39WF6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase Y family.
messages: Cell membrane
messages: Endoribonuclease that initiates mRNA decay.

269799:GMET RS01315
gene id: 269799:GMET_RS01315
uniprot id: Q39Z17
names: Similarity
messages: Belongs to the UPF0502 family.

269799:GMET RS03240
gene id: 269799:GMET_RS03240
uniprot id: Q39XY8
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

269799:GMET RS13515
gene id: 269799:GMET_RS13515
uniprot id: Q39S60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

269799:GMET RS16140
gene id: 269799:GMET_RS16140
uniprot id: Q39QP0
names: Subcellular Location Annotation
messages: Membrane

269799:GMET RS10025
gene id: 269799:GMET_RS10025
uniprot id: Q39U60
names: Function
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.

269799:GMET RS03130
gene id: 269799:GMET_RS03130
uniprot id: Q39Y11
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

269799:GMET RS00965
gene id: 269799:GMET_RS00965
uniprot id: Q39Z86
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

269799:GMET RS15000
gene id: 269799:GMET_RS15000
uniprot id: Q39RB7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

269799:GMET RS16870
gene id: 269799:GMET_RS16870
uniprot id: Q39Q96
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell inner membrane
messages: Component of the type II secretion system inner membrane complex required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm.
messages: Membrane

269799:GMET RS08015
gene id: 269799:GMET_RS08015
uniprot id: Q39V98
names: Similarity
messages: Belongs to the peptidase M29 family.

269799:GMET RS01050
gene id: 269799:GMET_RS01050
uniprot id: Q39Z69
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

269799:GMET RS07925
gene id: 269799:GMET_RS07925
uniprot id: Q39VB6
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

269799:GMET RS17000
gene id: 269799:GMET_RS17000
uniprot id: Q39Q70
names: Caution
names: Function
names: Similarity
messages: Belongs to the UbiX/PAD1 family.
messages: Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

269799:GMET RS04295
gene id: 269799:GMET_RS04295
uniprot id: Q39XC4
names: Subcellular Location Annotation
messages: Membrane

269799:GMET RS16030
gene id: 269799:GMET_RS16030
uniprot id: Q39QR2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

269799:GMET RS04500
gene id: 269799:GMET_RS04500
uniprot id: Q39X83
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

269799:GMET RS02370
gene id: 269799:GMET_RS02370
uniprot id: Q39YF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CbiQ family.
messages: Membrane

269799:GMET RS03030
gene id: 269799:GMET_RS03030
uniprot id: Q39Y25
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

269799:GMET RS10685
gene id: 269799:GMET_RS10685
uniprot id: Q39TS5
names: Subcellular Location Annotation
messages: Membrane

269799:GMET RS00645
gene id: 269799:GMET_RS00645
uniprot id: Q39ZE7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

269799:GMET RS17400
gene id: 269799:GMET_RS17400
uniprot id: Q39PZ5
names: Subcellular Location Annotation
messages: Membrane

269799:GMET RS16385
gene id: 269799:GMET_RS16385
uniprot id: Q39QJ2
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

269799:GMET RS06555
gene id: 269799:GMET_RS06555
uniprot id: Q39W36
names: Similarity
messages: Belongs to the PhoH family.

269799:GMET RS14085
gene id: 269799:GMET_RS14085
uniprot id: Q39RU5
names: Subcellular Location Annotation
messages: Membrane

269799:GMET RS09285
gene id: 269799:GMET_RS09285
uniprot id: Q39UK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

269799:GMET RS06330
gene id: 269799:GMET_RS06330
uniprot id: Q39W81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

269799:GMET RS03735
gene id: 269799:GMET_RS03735
uniprot id: Q39XN7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

269799:GMET RS15540
gene id: 269799:GMET_RS15540
uniprot id: Q39R10
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: Cell inner membrane
messages: FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

269799:GMET RS06845
gene id: 269799:GMET_RS06845
uniprot id: Q39VY1
names: Cofactor
names: Similarity
messages: Belongs to the monomeric-type IDH family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

269799:GMET RS16780
gene id: 269799:GMET_RS16780
uniprot id: Q39QB4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

269799:GMET RS01755
gene id: 269799:GMET_RS01755
uniprot id: Q39YS9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell inner membrane
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

269799:GMET RS15330
gene id: 269799:GMET_RS15330
uniprot id: Q39R52
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

269799:GMET RS17375
gene id: 269799:GMET_RS17375
uniprot id: Q39Q00
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

269799:GMET RS17225
gene id: 269799:GMET_RS17225
uniprot id: Q39Q27
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

269799:GMET RS03430
gene id: 269799:GMET_RS03430
uniprot id: Q39XU9
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

269799:GMET RS01100
gene id: 269799:GMET_RS01100
uniprot id: Q39Z59
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

269799:GMET RS08750
gene id: 269799:GMET_RS08750
uniprot id: Q39UV4
names: Similarity
messages: Belongs to the histone deacetylase family.

269799:GMET RS07725
gene id: 269799:GMET_RS07725
uniprot id: Q39VF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

269799:GMET RS15595
gene id: 269799:GMET_RS15595
uniprot id: Q39QZ9
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: Membrane

269799:GMET RS17855
gene id: 269799:GMET_RS17855
uniprot id: Q39PR0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

269799:GMET RS04785
gene id: 269799:GMET_RS04785
uniprot id: Q39X26
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

269799:GMET RS15535
gene id: 269799:GMET_RS15535
uniprot id: Q39R11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliN/MopA/SpaO family.
messages: Membrane

269799:GMET RS00615
gene id: 269799:GMET_RS00615
uniprot id: Q39ZF3
names: Similarity
messages: Belongs to the pyruvate kinase family.

269799:GMET RS00985
gene id: 269799:GMET_RS00985
uniprot id: Q39Z82
names: Similarity
messages: Belongs to the CinA family.

269799:GMET RS10180
gene id: 269799:GMET_RS10180
uniprot id: Q39U29
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

269799:GMET RS02170
gene id: 269799:GMET_RS02170
uniprot id: Q39YJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgI family.
messages: Periplasm
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

269799:GMET RS17065
gene id: 269799:GMET_RS17065
uniprot id: Q39Q58
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PdxA family.
messages: Binds 1 divalent metal cation per subunit. Can use ions such as Zn(2+), Mg(2+) or Co(2+).
messages: Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L-threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).
messages: Cytoplasm
messages: Homodimer.
messages: The active site is located at the dimer interface.

269799:GMET RS01635
gene id: 269799:GMET_RS01635
uniprot id: Q39YV4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

269799:GMET RS03185
gene id: 269799:GMET_RS03185
uniprot id: Q39Y00
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

269799:GMET RS09175
gene id: 269799:GMET_RS09175
uniprot id: Q39UM3
names: Subcellular Location Annotation
messages: Membrane

269799:GMET RS00750
gene id: 269799:GMET_RS00750
uniprot id: Q39ZC6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mg(2+). Can also accept Mn(2+).

269799:GMET RS02630
gene id: 269799:GMET_RS02630
uniprot id: Q39YA4
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Member of a two-component regulatory system.

269799:GMET RS14360
gene id: 269799:GMET_RS14360
uniprot id: Q39RP5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

269799:GMET RS08900
gene id: 269799:GMET_RS08900
uniprot id: Q39US4
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

269799:GMET RS04615
gene id: 269799:GMET_RS04615
uniprot id: Q39X60
names: Function
names: Similarity
names: Subunit
messages: Catalyzes the ADP transfer from ATP to D-glycero-beta-D-manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose.
messages: Catalyzes the phosphorylation of D-glycero-D-manno-heptose 7-phosphate at the C-1 position to selectively form D-glycero-beta-D-manno-heptose-1,7-bisphosphate.
messages: Homodimer.
messages: In the C-terminal section; belongs to the cytidylyltransferase family.
messages: In the N-terminal section; belongs to the carbohydrate kinase PfkB family.

269799:GMET RS03890
gene id: 269799:GMET_RS03890
uniprot id: Q39XK5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

269799:GMET RS15845
gene id: 269799:GMET_RS15845
uniprot id: Q39QU9
names: Subcellular Location Annotation
messages: Cell outer membrane

269799:GMET RS09870
gene id: 269799:GMET_RS09870
uniprot id: Q39U91
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate.
messages: Cytoplasm

269799:GMET RS09840
gene id: 269799:GMET_RS09840
uniprot id: Q39U97
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

269799:GMET RS12040
gene id: 269799:GMET_RS12040
uniprot id: Q39T09
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

269799:GMET RS04055
gene id: 269799:GMET_RS04055
uniprot id: Q39XH2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

269799:GMET RS09180
gene id: 269799:GMET_RS09180
uniprot id: Q39UM2
names: Similarity
messages: Belongs to the leucine-binding protein family.

269799:GMET RS15885
gene id: 269799:GMET_RS15885
uniprot id: Q39QU1
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

269799:GMET RS02385
gene id: 269799:GMET_RS02385
uniprot id: Q39YF4
names: Similarity
messages: Belongs to the CobH/CbiC family.

269799:GMET RS15110
gene id: 269799:GMET_RS15110
uniprot id: Q39R96
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

269799:GMET RS01855
gene id: 269799:GMET_RS01855
uniprot id: Q39YQ9
names: Subcellular Location Annotation
messages: Membrane

269799:GMET RS14765
gene id: 269799:GMET_RS14765
uniprot id: Q39RG5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

269799:GMET RS03230
gene id: 269799:GMET_RS03230
uniprot id: Q39XZ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

269799:GMET RS13690
gene id: 269799:GMET_RS13690
uniprot id: Q39S25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

269799:GMET RS03420
gene id: 269799:GMET_RS03420
uniprot id: Q39XV1
names: Similarity
messages: Belongs to the radical SAM superfamily. NifB family.

269799:GMET RS16010
gene id: 269799:GMET_RS16010
uniprot id: Q39QR6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

269799:GMET RS15615
gene id: 269799:GMET_RS15615
uniprot id: Q39QZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod.

269799:GMET RS01915
gene id: 269799:GMET_RS01915
uniprot id: Q39YP7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

269799:GMET RS08865
gene id: 269799:GMET_RS08865
uniprot id: Q39UT1
names: Similarity
messages: Belongs to the dGTPase family. Type 2 subfamily.

269799:GMET RS03040
gene id: 269799:GMET_RS03040
uniprot id: Q39Y23
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

269799:GMET RS06255
gene id: 269799:GMET_RS06255
uniprot id: Q39W96
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.

269799:GMET RS04885
gene id: 269799:GMET_RS04885
uniprot id: Q39X06
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

269799:GMET RS03150
gene id: 269799:GMET_RS03150
uniprot id: Q39Y07
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

269799:GMET RS08260
gene id: 269799:GMET_RS08260
uniprot id: Q39V49
names: Similarity
messages: Belongs to the group II decarboxylase family.

269799:GMET RS05230
gene id: 269799:GMET_RS05230
uniprot id: Q39WT9
names: Similarity
messages: Belongs to the AOR/FOR family.

269799:GMET RS11895
gene id: 269799:GMET_RS11895
uniprot id: Q39T39
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

269799:GMET RS00765
gene id: 269799:GMET_RS00765
uniprot id: Q39ZC5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

269799:GMET RS02640
gene id: 269799:GMET_RS02640
uniprot id: Q39YA2
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

269799:GMET RS13040
gene id: 269799:GMET_RS13040
uniprot id: Q39SF7
names: Subcellular Location Annotation
messages: Membrane

269799:GMET RS08040
gene id: 269799:GMET_RS08040
uniprot id: Q39V93
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

269799:GMET RS04625
gene id: 269799:GMET_RS04625
uniprot id: Q39X58
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

269799:GMET RS05585
gene id: 269799:GMET_RS05585
uniprot id: Q39WM1
names: Similarity
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.

269799:GMET RS10835
gene id: 269799:GMET_RS10835
uniprot id: Q39TP5
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

269799:GMET RS13835
gene id: 269799:GMET_RS13835
uniprot id: Q39RZ6
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

269799:GMET RS09495
gene id: 269799:GMET_RS09495
uniprot id: Q39UG6
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

269799:GMET RS00140
gene id: 269799:GMET_RS00140
uniprot id: Q39ZP6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

269799:GMET RS03175
gene id: 269799:GMET_RS03175
uniprot id: Q39Y02
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

269799:GMET RS07190
gene id: 269799:GMET_RS07190
uniprot id: Q39VR4
names: Activity Regulation
names: Caution
names: Domain
names: Function
names: Similarity
messages: Belongs to the GlnD family.
messages: Has four distinct domains: an N-terminal nucleotidyltransferase (NT) domain responsible for UTase activity, a central HD domain that encodes UR activity, and two C-terminal ACT domains that seem to have a role in glutamine sensing.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism.
messages: Uridylyltransferase (UTase) activity is inhibited by glutamine, while glutamine activates uridylyl-removing (UR) activity.

269799:GMET RS07960
gene id: 269799:GMET_RS07960
uniprot id: Q39VA9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

269799:GMET RS17070
gene id: 269799:GMET_RS17070
uniprot id: Q39Q57
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

269799:GMET RS12570
gene id: 269799:GMET_RS12570
uniprot id: Q39SQ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 90 family.
messages: Cytoplasm
messages: Homodimer.
messages: Molecular chaperone. Has ATPase activity.

269799:GMET RS05365
gene id: 269799:GMET_RS05365
uniprot id: Q39WR5
names: Function
names: Similarity
messages: Belongs to the transposase 11 family.
messages: Involved in the transposition of the insertion sequence IS5.

269799:GMET RS17740
gene id: 269799:GMET_RS17740
uniprot id: Q39PT3
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

269799:GMET RS10380
gene id: 269799:GMET_RS10380
uniprot id: Q39TY8
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

269799:GMET RS03090
gene id: 269799:GMET_RS03090
uniprot id: Q39Y19
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell inner membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

269799:GMET RS02080
gene id: 269799:GMET_RS02080
uniprot id: Q39YL5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell inner membrane
messages: Self-interacts. Interacts with FtsZ.

269799:GMET RS09240
gene id: 269799:GMET_RS09240
uniprot id: Q39UL0
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

269799:GMET RS13680
gene id: 269799:GMET_RS13680
uniprot id: Q39S27
names: Similarity
messages: Belongs to the acylphosphatase family.

269799:GMET RS07990
gene id: 269799:GMET_RS07990
uniprot id: Q39VA3
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

269799:GMET RS04595
gene id: 269799:GMET_RS04595
uniprot id: Q39X64
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

269799:GMET RS00775
gene id: 269799:GMET_RS00775
uniprot id: Q39ZC3
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

269799:GMET RS14265
gene id: 269799:GMET_RS14265
uniprot id: Q39RQ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

269799:GMET RS11845
gene id: 269799:GMET_RS11845
uniprot id: Q39T49
names: Function
names: Similarity
messages: Belongs to the LpxB family.
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

269799:GMET RS04070
gene id: 269799:GMET_RS04070
uniprot id: Q39XG9
names: Subcellular Location Annotation
messages: Membrane

269799:GMET RS03200
gene id: 269799:GMET_RS03200
uniprot id: Q39XZ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

269799:GMET RS07195
gene id: 269799:GMET_RS07195
uniprot id: Q39VR3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

269799:GMET RS08890
gene id: 269799:GMET_RS08890
uniprot id: Q39US6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

269799:GMET RS05925
gene id: 269799:GMET_RS05925
uniprot id: Q39WF4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

269799:GMET RS04445
gene id: 269799:GMET_RS04445
uniprot id: Q39X95
names: Subcellular Location Annotation
messages: Membrane

269799:GMET RS10130
gene id: 269799:GMET_RS10130
uniprot id: Q39U39
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
messages: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.

269799:GMET RS16990
gene id: 269799:GMET_RS16990
uniprot id: Q39Q72
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the radical SAM superfamily. MqnC family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2).

269799:GMET RS03080
gene id: 269799:GMET_RS03080
uniprot id: Q39Y20
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

269799:GMET RS11415
gene id: 269799:GMET_RS11415
uniprot id: Q39TD3
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

269799:GMET RS03295
gene id: 269799:GMET_RS03295
uniprot id: Q39XX6
names: Subcellular Location Annotation
messages: Membrane

269799:GMET RS03260
gene id: 269799:GMET_RS03260
uniprot id: Q39XY4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

269799:GMET RS16810
gene id: 269799:GMET_RS16810
uniprot id: Q39QA8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

269799:GMET RS08670
gene id: 269799:GMET_RS08670
uniprot id: Q39UX1
names: Caution
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IcmF family.
messages: Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly.
messages: Homodimer.
messages: Is composed of four functional domains: the N-terminal 5'-deoxyadenosylcobalamin binding region that is homologous to the small subunit of ICM (IcmB), a middle P-loop GTPase domain (MeaI) that likely acts as a chaperone for ICM, a structured linker region involved in dimer formation, and a C-terminal part that is homologous to the large substrate-binding subunit of ICM (IcmA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

269799:GMET RS05080
gene id: 269799:GMET_RS05080
uniprot id: Q39WW6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.

269799:GMET RS15810
gene id: 269799:GMET_RS15810
uniprot id: Q39QV6
names: Similarity
messages: Belongs to the GcvT family.

269799:GMET RS09715
gene id: 269799:GMET_RS09715
uniprot id: Q39UC2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b family.
messages: Binds 2 heme groups non-covalently.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
messages: Membrane
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

269799:GMET RS05855
gene id: 269799:GMET_RS05855
uniprot id: Q39WG8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the adenylate cyclase family. DacA/CdaA subfamily.
messages: Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably a homodimer.

269799:GMET RS04980
gene id: 269799:GMET_RS04980
uniprot id: Q39WY7
names: Similarity
messages: Belongs to the MlaA family.

269799:GMET RS08515
gene id: 269799:GMET_RS08515
uniprot id: Q39V01
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

269799:GMET RS03880
gene id: 269799:GMET_RS03880
uniprot id: Q39XK7
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

269799:GMET RS07740
gene id: 269799:GMET_RS07740
uniprot id: Q39VF3
names: Similarity
messages: Belongs to the CbbQ/NirQ/NorQ/GpvN family.

269799:GMET RS17700
gene id: 269799:GMET_RS17700
uniprot id: Q39PU1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.

269799:GMET RS01005
gene id: 269799:GMET_RS01005
uniprot id: Q39Z78
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

269799:GMET RS03755
gene id: 269799:GMET_RS03755
uniprot id: Q39XN3
names: Similarity
messages: Belongs to the peptidase S8 family.

269799:GMET RS05625
gene id: 269799:GMET_RS05625
uniprot id: Q39WL3
names: Similarity
messages: Belongs to the PrpD family.

269799:GMET RS02195
gene id: 269799:GMET_RS02195
uniprot id: Q39YJ2
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Secreted

269799:GMET RS00495
gene id: 269799:GMET_RS00495
uniprot id: Q39ZH6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

269799:GMET RS03850
gene id: 269799:GMET_RS03850
uniprot id: Q39XL3
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

269799:GMET RS10510
gene id: 269799:GMET_RS10510
uniprot id: Q39TW1
names: Similarity
messages: Belongs to the HdrA family.

269799:GMET RS09770
gene id: 269799:GMET_RS09770
uniprot id: Q39UB1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

269799:GMET RS03860
gene id: 269799:GMET_RS03860
uniprot id: Q39XL1
names: Cofactor
names: Similarity
messages: Belongs to the WrbA family.
messages: Binds 1 FMN per monomer.

269799:GMET RS07895
gene id: 269799:GMET_RS07895
uniprot id: Q39VC1
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

269799:GMET RS06930
gene id: 269799:GMET_RS06930
uniprot id: Q39VW4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell outer membrane
messages: CyaE is necessary for transport of calmodulin-sensitive adenylate cyclase-hemolysin (cyclolysin).

269799:GMET RS03660
gene id: 269799:GMET_RS03660
uniprot id: Q39XQ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

269799:GMET RS08720
gene id: 269799:GMET_RS08720
uniprot id: Q39UW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acyl-ACP thioesterase family.
messages: chloroplast

269799:GMET RS16695
gene id: 269799:GMET_RS16695
uniprot id: Q39QD0
names: Similarity
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.

269799:GMET RS17180
gene id: 269799:GMET_RS17180
uniprot id: Q39Q36
names: Similarity
messages: Belongs to the HdrA family.

269799:GMET RS11665
gene id: 269799:GMET_RS11665
uniprot id: Q39T85
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

269799:GMET RS01275
gene id: 269799:GMET_RS01275
uniprot id: Q39Z25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

269799:GMET RS11520
gene id: 269799:GMET_RS11520
uniprot id: Q39TB4
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

269799:GMET RS15115
gene id: 269799:GMET_RS15115
uniprot id: Q39R95
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamD family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

269799:GMET RS11905
gene id: 269799:GMET_RS11905
uniprot id: Q39T37
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

269799:GMET RS08225
gene id: 269799:GMET_RS08225
uniprot id: Q39V56
names: Similarity
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the malic enzymes family.

269799:GMET RS04910
gene id: 269799:GMET_RS04910
uniprot id: Q39X01
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

269799:GMET RS05790
gene id: 269799:GMET_RS05790
uniprot id: Q39WI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

269799:GMET RS07930
gene id: 269799:GMET_RS07930
uniprot id: Q39VB5
names: Similarity
messages: Belongs to the YkuD family.

269799:GMET RS00975
gene id: 269799:GMET_RS00975
uniprot id: Q39Z84
names: Similarity
messages: Belongs to the LarC family.

269799:GMET RS16865
gene id: 269799:GMET_RS16865
uniprot id: Q39Q97
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: ATPase component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm. Acts as a molecular motor to provide the energy that is required for assembly of the pseudopilus and the extrusion of substrates generated in the cytoplasm.
messages: Belongs to the GSP E family.
messages: Cell inner membrane

269799:GMET RS07295
gene id: 269799:GMET_RS07295
uniprot id: Q39VP2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

269799:GMET RS17795
gene id: 269799:GMET_RS17795
uniprot id: Q39PS2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

269799:GMET RS14315
gene id: 269799:GMET_RS14315
uniprot id: Q39RP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. DIT1 subfamily.
messages: Membrane

269799:GMET RS06215
gene id: 269799:GMET_RS06215
uniprot id: Q39WA4
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

269799:GMET RS09450
gene id: 269799:GMET_RS09450
uniprot id: Q39UH1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

269799:GMET RS00300
gene id: 269799:GMET_RS00300
uniprot id: Q39ZL5
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

269799:GMET RS12020
gene id: 269799:GMET_RS12020
uniprot id: Q39T14
names: Subcellular Location Annotation
messages: Membrane

269799:GMET RS16175
gene id: 269799:GMET_RS16175
uniprot id: Q39QN3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

269799:GMET RS16215
gene id: 269799:GMET_RS16215
uniprot id: Q39QM5
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.

269799:GMET RS10580
gene id: 269799:GMET_RS10580
uniprot id: Q39TU7
names: Similarity
messages: Belongs to the phosphate acetyltransferase and butyryltransferase family.

269799:GMET RS14560
gene id: 269799:GMET_RS14560
uniprot id: Q39RK5
names: Subcellular Location Annotation
messages: Membrane

269799:GMET RS14060
gene id: 269799:GMET_RS14060
uniprot id: Q39RV0
names: Similarity
messages: Belongs to the SUI1 family.

269799:GMET RS07920
gene id: 269799:GMET_RS07920
uniprot id: Q39VB7
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

269799:GMET RS09625
gene id: 269799:GMET_RS09625
uniprot id: Q39UE1
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

269799:GMET RS16940
gene id: 269799:GMET_RS16940
uniprot id: Q39Q82
names: Function
names: Similarity
messages: Belongs to the MqnA/MqnD family. MqnD subfamily.
messages: Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2).

269799:GMET RS04800
gene id: 269799:GMET_RS04800
uniprot id: Q39X23
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A24 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Plays an essential role in type IV pili and type II pseudopili formation by proteolytically removing the leader sequence from substrate proteins and subsequently monomethylating the alpha-amino group of the newly exposed N-terminal phenylalanine.

269799:GMET RS04895
gene id: 269799:GMET_RS04895
uniprot id: Q39X04
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm

269799:GMET RS16960
gene id: 269799:GMET_RS16960
uniprot id: Q39Q78
names: Function
names: Similarity
messages: Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PDRP subfamily.
messages: Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation.

269799:GMET RS07200
gene id: 269799:GMET_RS07200
uniprot id: Q39VR2
names: Function
names: Similarity
messages: Belongs to the BPG-independent phosphoglycerate mutase family. A-PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

269799:GMET RS17355
gene id: 269799:GMET_RS17355
uniprot id: Q39Q04
names: Subcellular Location Annotation
messages: Membrane

269799:GMET RS11890
gene id: 269799:GMET_RS11890
uniprot id: Q39T40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

269799:GMET RS08885
gene id: 269799:GMET_RS08885
uniprot id: Q39US7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell inner membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

269799:GMET RS06115
gene id: 269799:GMET_RS06115
uniprot id: Q39WC2
names: Subcellular Location Annotation
messages: Cytoplasm

269799:GMET RS08620
gene id: 269799:GMET_RS08620
uniprot id: Q39UY0
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

269799:GMET RS15815
gene id: 269799:GMET_RS15815
uniprot id: Q39QV5
names: Function
names: Similarity
messages: Belongs to the HypA/HybF family.
messages: Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.

269799:GMET RS12445
gene id: 269799:GMET_RS12445
uniprot id: Q39SS7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

269799:GMET RS05835
gene id: 269799:GMET_RS05835
uniprot id: Q39WH2
names: Similarity
messages: Belongs to the UPF0235 family.

269799:GMET RS11090
gene id: 269799:GMET_RS11090
uniprot id: Q39TJ5
names: Similarity
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

269799:GMET RS10450
gene id: 269799:GMET_RS10450
uniprot id: Q39TX4
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

269799:GMET RS14730
gene id: 269799:GMET_RS14730
uniprot id: Q39RH2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

269799:GMET RS11250
gene id: 269799:GMET_RS11250
uniprot id: Q39TG3
names: Similarity
messages: Belongs to the thioesterase PaaI family.

269799:GMET RS08465
gene id: 269799:GMET_RS08465
uniprot id: Q39V11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell inner membrane
messages: Membrane

269799:GMET RS10040
gene id: 269799:GMET_RS10040
uniprot id: Q39U57
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

269799:GMET RS12205
gene id: 269799:GMET_RS12205
uniprot id: Q39SX5
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

269799:GMET RS05885
gene id: 269799:GMET_RS05885
uniprot id: Q39WG2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

269799:GMET RS05335
gene id: 269799:GMET_RS05335
uniprot id: Q39WS1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell inner membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

269799:GMET RS09570
gene id: 269799:GMET_RS09570
uniprot id: Q39UF2
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA.
messages: Belongs to the helicase family. UvrD subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding. Interacts with RecA.
messages: The C-terminal domain has nuclease activity and interacts with RecD. It interacts with RecA, facilitating its loading onto ssDNA.
messages: The N-terminal DNA-binding domain is a ssDNA-dependent ATPase and has ATP-dependent 3'-5' helicase function. This domain interacts with RecC.

269799:GMET RS03145
gene id: 269799:GMET_RS03145
uniprot id: Q39Y08
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

269799:GMET RS11715
gene id: 269799:GMET_RS11715
uniprot id: Q39T75
names: Similarity
messages: Belongs to the RutC family.

269799:GMET RS01105
gene id: 269799:GMET_RS01105
uniprot id: Q39Z58
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

269799:GMET RS12475
gene id: 269799:GMET_RS12475
uniprot id: Q39SS1
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

269799:GMET RS02740
gene id: 269799:GMET_RS02740
uniprot id: Q39Y82
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.

269799:GMET RS11860
gene id: 269799:GMET_RS11860
uniprot id: Q39T46
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
messages: Cytoplasm
messages: Homotrimer.
messages: Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

269799:GMET RS11025
gene id: 269799:GMET_RS11025
uniprot id: Q39TK9
names: Similarity
messages: Belongs to the CFA/CMAS family.

269799:GMET RS13960
gene id: 269799:GMET_RS13960
uniprot id: Q39RX0
names: Similarity
messages: Belongs to the carbamate kinase family.

269799:GMET RS11400
gene id: 269799:GMET_RS11400
uniprot id: Q39TD6
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

269799:GMET RS08735
gene id: 269799:GMET_RS08735
uniprot id: Q39UV7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Monomer.

269799:GMET RS17715
gene id: 269799:GMET_RS17715
uniprot id: Q39PT8
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

269799:GMET RS09475
gene id: 269799:GMET_RS09475
uniprot id: Q39UH0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

269799:GMET RS14395
gene id: 269799:GMET_RS14395
uniprot id: Q39RN8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

269799:GMET RS06800
gene id: 269799:GMET_RS06800
uniprot id: Q39VY8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glutamine synthetase family.
messages: Cytoplasm
messages: Oligomer of 12 subunits arranged in the form of two hexagons.

269799:GMET RS06155
gene id: 269799:GMET_RS06155
uniprot id: Q39WB5
names: Similarity
messages: Belongs to the TlyA family.

269799:GMET RS12050
gene id: 269799:GMET_RS12050
uniprot id: Q39T06
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell inner membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

269799:GMET RS09835
gene id: 269799:GMET_RS09835
uniprot id: Q39U98
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

269799:GMET RS01965
gene id: 269799:GMET_RS01965
uniprot id: Q39YN7
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

269799:GMET RS11395
gene id: 269799:GMET_RS11395
uniprot id: Q39TD7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

269799:GMET RS16060
gene id: 269799:GMET_RS16060
uniprot id: Q39QQ6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
messages: Cytoplasm

269799:GMET RS08195
gene id: 269799:GMET_RS08195
uniprot id: Q39V62
names: Similarity
messages: Belongs to the threonine synthase family.

269799:GMET RS09790
gene id: 269799:GMET_RS09790
uniprot id: Q39UA7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

269799:GMET RS12115
gene id: 269799:GMET_RS12115
uniprot id: Q39SZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

269799:GMET RS06495
gene id: 269799:GMET_RS06495
uniprot id: Q39W48
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

269799:GMET RS05990
gene id: 269799:GMET_RS05990
uniprot id: Q39WE7
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

269799:GMET RS01060
gene id: 269799:GMET_RS01060
uniprot id: Q39Z67
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

269799:GMET RS17645
gene id: 269799:GMET_RS17645
uniprot id: Q39PU9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

269799:GMET RS07755
gene id: 269799:GMET_RS07755
uniprot id: Q39VE9
names: Similarity
names: Subunit
messages: Belongs to the organic radical-activating enzymes family.
messages: Monomer.

269799:GMET RS01920
gene id: 269799:GMET_RS01920
uniprot id: Q39YP6
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

269799:GMET RS06435
gene id: 269799:GMET_RS06435
uniprot id: Q39W60
names: Similarity
messages: Belongs to the SIS family. GutQ/KpsF subfamily.

269799:GMET RS14615
gene id: 269799:GMET_RS14615
uniprot id: Q39RJ5
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.

269799:GMET RS08605
gene id: 269799:GMET_RS08605
uniprot id: Q39UY3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

269799:GMET RS08710
gene id: 269799:GMET_RS08710
uniprot id: Q39UW3
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

269799:GMET RS06060
gene id: 269799:GMET_RS06060
uniprot id: Q39WD3
names: Subcellular Location Annotation
messages: Membrane

269799:GMET RS08045
gene id: 269799:GMET_RS08045
uniprot id: Q39V92
names: Similarity
messages: Belongs to the fabD family.

269799:GMET RS00840
gene id: 269799:GMET_RS00840
uniprot id: Q39ZB0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

269799:GMET RS16400
gene id: 269799:GMET_RS16400
uniprot id: Q39QI9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

269799:GMET RS17410
gene id: 269799:GMET_RS17410
uniprot id: Q39PZ3
names: Similarity
messages: Belongs to the GSP E family.

269799:GMET RS00335
gene id: 269799:GMET_RS00335
uniprot id: Q39ZK8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

269799:GMET RS11115
gene id: 269799:GMET_RS11115
uniprot id: Q39TJ0
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

269799:GMET RS02460
gene id: 269799:GMET_RS02460
uniprot id: Q39YD8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

269799:GMET RS02720
gene id: 269799:GMET_RS02720
uniprot id: Q39Y86
names: Similarity
messages: Belongs to the FldB/FldC dehydratase alpha/beta subunit family.

269799:GMET RS11875
gene id: 269799:GMET_RS11875
uniprot id: Q39T43
names: Similarity
messages: Belongs to the Skp family.

269799:GMET RS04715
gene id: 269799:GMET_RS04715
uniprot id: Q39X40
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

269799:GMET RS00705
gene id: 269799:GMET_RS00705
uniprot id: Q39ZD5
names: Subcellular Location Annotation
messages: Membrane

269799:GMET RS17825
gene id: 269799:GMET_RS17825
uniprot id: Q39PR6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

269799:GMET RS15155
gene id: 269799:GMET_RS15155
uniprot id: Q39R87
names: Similarity
messages: Belongs to the complex I 75 kDa subunit family.

269799:GMET RS02955
gene id: 269799:GMET_RS02955
uniprot id: Q39Y39
names: Subcellular Location Annotation
messages: Membrane

269799:GMET RS13600
gene id: 269799:GMET_RS13600
uniprot id: Q39S43
names: Similarity
messages: Belongs to the peptidase S41A family.

269799:GMET RS07785
gene id: 269799:GMET_RS07785
uniprot id: Q39VE3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

269799:GMET RS11070
gene id: 269799:GMET_RS11070
uniprot id: Q39TJ9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

269799:GMET RS16205
gene id: 269799:GMET_RS16205
uniprot id: Q39QM7
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

269799:GMET RS12620
gene id: 269799:GMET_RS12620
uniprot id: Q39SP1
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

269799:GMET RS00950
gene id: 269799:GMET_RS00950
uniprot id: Q39Z89
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

269799:GMET RS06545
gene id: 269799:GMET_RS06545
uniprot id: Q39W38
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.

269799:GMET RS12110
gene id: 269799:GMET_RS12110
uniprot id: Q39SZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

269799:GMET RS01885
gene id: 269799:GMET_RS01885
uniprot id: Q39YQ3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidylate synthase ThyX family.
messages: Binds 4 FAD per tetramer. Each FAD binding site is formed by three monomers.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
messages: Homotetramer.

269799:GMET RS05400
gene id: 269799:GMET_RS05400
uniprot id: Q39WQ8
names: Function
names: Similarity
messages: Belongs to the CheD family.
messages: Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.

269799:GMET RS13770
gene id: 269799:GMET_RS13770
uniprot id: Q39S09
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

269799:GMET RS06810
gene id: 269799:GMET_RS06810
uniprot id: Q39VY6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

269799:GMET RS00980
gene id: 269799:GMET_RS00980
uniprot id: Q39Z83
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG).

269799:GMET RS12105
gene id: 269799:GMET_RS12105
uniprot id: Q39SZ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm

269799:GMET RS02465
gene id: 269799:GMET_RS02465
uniprot id: Q39YD7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the transcriptional regulatory CopG/NikR family.
messages: Binds 1 nickel ion per subunit.
messages: Transcriptional regulator.

269799:GMET RS09520
gene id: 269799:GMET_RS09520
uniprot id: Q39UG1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

269799:GMET RS03945
gene id: 269799:GMET_RS03945
uniprot id: Q39XJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MlaE permease family.
messages: Cell inner membrane
messages: Membrane

269799:GMET RS17475
gene id: 269799:GMET_RS17475
uniprot id: Q39PY4
names: Similarity
messages: Belongs to the YkuD family.

269799:GMET RS02590
gene id: 269799:GMET_RS02590
uniprot id: Q39YB2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

269799:GMET RS17705
gene id: 269799:GMET_RS17705
uniprot id: Q39PU0
names: Similarity
messages: Belongs to the CapA family.

269799:GMET RS03045
gene id: 269799:GMET_RS03045
uniprot id: Q39Y22
names: Cofactor
names: Similarity
messages: Belongs to the UPF0313 family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

269799:GMET RS12565
gene id: 269799:GMET_RS12565
uniprot id: Q39SQ4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

269799:GMET RS15765
gene id: 269799:GMET_RS15765
uniprot id: Q39QW5
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

269799:GMET RS17880
gene id: 269799:GMET_RS17880
uniprot id: Q39PQ5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

269799:GMET RS01265
gene id: 269799:GMET_RS01265
uniprot id: Q39Z27
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Binds a copper A center.
messages: Cell membrane
messages: Membrane
messages: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).

269799:GMET RS12550
gene id: 269799:GMET_RS12550
uniprot id: Q39SQ7
names: Similarity
messages: Belongs to the TrpC family.

269799:GMET RS00005
gene id: 269799:GMET_RS00005
uniprot id: Q39ZS3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

269799:GMET RS12660
gene id: 269799:GMET_RS12660
uniprot id: Q39SN4
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

269799:GMET RS12305
gene id: 269799:GMET_RS12305
uniprot id: Q39SV5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell inner membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

269799:GMET RS12375
gene id: 269799:GMET_RS12375
uniprot id: Q39SU1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

269799:GMET RS00290
gene id: 269799:GMET_RS00290
uniprot id: Q39ZL7
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

269799:GMET RS04110
gene id: 269799:GMET_RS04110
uniprot id: Q39XG1
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

269799:GMET RS12470
gene id: 269799:GMET_RS12470
uniprot id: Q39SS2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

269799:GMET RS03120
gene id: 269799:GMET_RS03120
uniprot id: Q39Y13
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

269799:GMET RS09250
gene id: 269799:GMET_RS09250
uniprot id: Q39UK8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

269799:GMET RS03220
gene id: 269799:GMET_RS03220
uniprot id: Q39XZ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

269799:GMET RS03215
gene id: 269799:GMET_RS03215
uniprot id: Q39XZ4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

269799:GMET RS09665
gene id: 269799:GMET_RS09665
uniprot id: Q39UD2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

269799:GMET RS07675
gene id: 269799:GMET_RS07675
uniprot id: Q39VG6
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

269799:GMET RS01000
gene id: 269799:GMET_RS01000
uniprot id: Q39Z79
names: Similarity
messages: Belongs to the GSP E family.

269799:GMET RS07345
gene id: 269799:GMET_RS07345
uniprot id: Q39VN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

269799:GMET RS09530
gene id: 269799:GMET_RS09530
uniprot id: Q39UF9
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

269799:GMET RS17590
gene id: 269799:GMET_RS17590
uniprot id: Q39PW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

269799:GMET RS14570
gene id: 269799:GMET_RS14570
uniprot id: Q39RK3
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

269799:GMET RS01195
gene id: 269799:GMET_RS01195
uniprot id: Q39Z42
names: Subcellular Location Annotation
messages: Cytoplasm

269799:GMET RS10005
gene id: 269799:GMET_RS10005
uniprot id: Q39U64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Cell inner membrane
messages: Membrane

269799:GMET RS11780
gene id: 269799:GMET_RS11780
uniprot id: Q39T62
names: Subcellular Location Annotation
messages: Periplasm

269799:GMET RS03575
gene id: 269799:GMET_RS03575
uniprot id: Q39XS0
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

269799:GMET RS00010
gene id: 269799:GMET_RS00010
uniprot id: Q39ZS2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

269799:GMET RS17775
gene id: 269799:GMET_RS17775
uniprot id: Q39PS6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell inner membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

269799:GMET RS08345
gene id: 269799:GMET_RS08345
uniprot id: Q39V34
names: Similarity
messages: Belongs to the creatininase superfamily.

269799:GMET RS16235
gene id: 269799:GMET_RS16235
uniprot id: Q39QM1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Fur family.
messages: Cytoplasm
messages: Homodimer.

269799:GMET RS12155
gene id: 269799:GMET_RS12155
uniprot id: Q39SY5
names: Subcellular Location Annotation
messages: Membrane

269799:GMET RS05620
gene id: 269799:GMET_RS05620
uniprot id: Q39WL4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family.
messages: Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate.
messages: Homotetramer; dimer of dimers.
messages: Involved in the catabolism of short chain fatty acids (SCFA) via the 2-methylcitrate cycle (propionate degradation route). Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate via an alpha-carboxy-carbanion intermediate.

269799:GMET RS12985
gene id: 269799:GMET_RS12985
uniprot id: Q39WL7
names: Similarity
messages: Belongs to the transposase IS21/IS408/IS1162 family.

269799:GMET RS05205
gene id: 269799:GMET_RS05205
uniprot id: Q39WU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

269799:GMET RS15010
gene id: 269799:GMET_RS15010
uniprot id: Q39RB5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AP endonuclease 2 family.
messages: Binds 3 Zn(2+) ions.
messages: Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.

269799:GMET RS08910
gene id: 269799:GMET_RS08910
uniprot id: Q39US2
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

269799:GMET RS16815
gene id: 269799:GMET_RS16815
uniprot id: Q39QA7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

269799:GMET RS14415
gene id: 269799:GMET_RS14415
uniprot id: Q39RN4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

269799:GMET RS03655
gene id: 269799:GMET_RS03655
uniprot id: Q39XQ3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

269799:GMET RS13045
gene id: 269799:GMET_RS13045
uniprot id: Q39SF6
names: Subcellular Location Annotation
messages: Membrane

269799:GMET RS15175
gene id: 269799:GMET_RS15175
uniprot id: Q39R83
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

269799:GMET RS14260
gene id: 269799:GMET_RS14260
uniprot id: Q39RR0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

269799:GMET RS15610
gene id: 269799:GMET_RS15610
uniprot id: Q39QZ6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

269799:GMET RS15520
gene id: 269799:GMET_RS15520
uniprot id: Q39R14
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

269799:GMET RS08835
gene id: 269799:GMET_RS08835
uniprot id: Q39UT7
names: Similarity
messages: Belongs to the glutamate synthase family.

269799:GMET RS14760
gene id: 269799:GMET_RS14760
uniprot id: Q39RG6
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.

269799:GMET RS09860
gene id: 269799:GMET_RS09860
uniprot id: Q39U93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

269799:GMET RS05650
gene id: 269799:GMET_RS05650
uniprot id: Q39WK8
names: Similarity
messages: Belongs to the myoviridae tail sheath protein family.

269799:GMET RS17730
gene id: 269799:GMET_RS17730
uniprot id: Q39PT5
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

269799:GMET RS15705
gene id: 269799:GMET_RS15705
uniprot id: Q39QX7
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell inner membrane

269799:GMET RS12195
gene id: 269799:GMET_RS12195
uniprot id: Q39SX7
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

269799:GMET RS08065
gene id: 269799:GMET_RS08065
uniprot id: Q39V88
names: Similarity
messages: Belongs to the LacAB/RpiB family.

269799:GMET RS03770
gene id: 269799:GMET_RS03770
uniprot id: Q39XN0
names: Function
names: Similarity
messages: Belongs to the QueH family.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).

269799:GMET RS05800
gene id: 269799:GMET_RS05800
uniprot id: Q39WH9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GDT1 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

269799:GMET RS15215
gene id: 269799:GMET_RS15215
uniprot id: Q39R75
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.

269799:GMET RS06365
gene id: 269799:GMET_RS06365
uniprot id: Q39W74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

269799:GMET RS07700
gene id: 269799:GMET_RS07700
uniprot id: Q39VG1
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

269799:GMET RS14300
gene id: 269799:GMET_RS14300
uniprot id: Q39RQ2
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

269799:GMET RS12360
gene id: 269799:GMET_RS12360
uniprot id: Q39SU4
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

269799:GMET RS01420
gene id: 269799:GMET_RS01420
uniprot id: Q39WR5
names: Function
names: Similarity
messages: Belongs to the transposase 11 family.
messages: Involved in the transposition of the insertion sequence IS5.

269799:GMET RS14330
gene id: 269799:GMET_RS14330
uniprot id: Q39RP6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
messages: Heterodimer composed of CysD, the smaller subunit, and CysN.
messages: With CysD forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.

269799:GMET RS04260
gene id: 269799:GMET_RS04260
uniprot id: Q39XD1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

269799:GMET RS00295
gene id: 269799:GMET_RS00295
uniprot id: Q39ZL6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).

269799:GMET RS01900
gene id: 269799:GMET_RS01900
uniprot id: Q39YQ0
names: Caution
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

269799:GMET RS04440
gene id: 269799:GMET_RS04440
uniprot id: Q39X96
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

269799:GMET RS12295
gene id: 269799:GMET_RS12295
uniprot id: Q39SV7
names: Similarity
messages: Belongs to the FeoA family.

269799:GMET RS09830
gene id: 269799:GMET_RS09830
uniprot id: Q39U99
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

269799:GMET RS10425
gene id: 269799:GMET_RS10425
uniprot id: Q39TX9
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

269799:GMET RS15830
gene id: 269799:GMET_RS15830
uniprot id: Q39QV2
names: Function
names: Similarity
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

269799:GMET RS06325
gene id: 269799:GMET_RS06325
uniprot id: Q39W82
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).

269799:GMET RS09610
gene id: 269799:GMET_RS09610
uniprot id: Q39UE4
names: Similarity
names: Subunit
messages: Belongs to the CmpA/NrtA family.
messages: Heterodimer of a large and a small subunit.

269799:GMET RS00585
gene id: 269799:GMET_RS00585
uniprot id: Q39ZF9
names: Similarity
messages: Belongs to the HypE family.

269799:GMET RS12130
gene id: 269799:GMET_RS12130
uniprot id: Q39SZ0
names: Similarity
messages: Belongs to the peptidase C56 family.

269799:GMET RS01770
gene id: 269799:GMET_RS01770
uniprot id: Q39YS6
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

269799:GMET RS12250
gene id: 269799:GMET_RS12250
uniprot id: Q39SW6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpA family.
messages: Cell inner membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds the periplasmic potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

269799:GMET RS05195
gene id: 269799:GMET_RS05195
uniprot id: Q39WU6
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

269799:GMET RS17315
gene id: 269799:GMET_RS17315
uniprot id: Q39Q12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0394 family.
messages: Membrane

269799:GMET RS08030
gene id: 269799:GMET_RS08030
uniprot id: Q39V95
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

269799:GMET RS05190
gene id: 269799:GMET_RS05190
uniprot id: Q39WU7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

269799:GMET RS04955
gene id: 269799:GMET_RS04955
uniprot id: Q39WZ2
names: Similarity
messages: Belongs to the phosphohexose mutase family.

269799:GMET RS16820
gene id: 269799:GMET_RS16820
uniprot id: Q39QA6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

269799:GMET RS15925
gene id: 269799:GMET_RS15925
uniprot id: Q39QT3
names: Similarity
messages: Belongs to the phosphohexose mutase family.

269799:GMET RS04680
gene id: 269799:GMET_RS04680
uniprot id: Q39X47
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

269799:GMET RS11575
gene id: 269799:GMET_RS11575
uniprot id: Q39TA3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

269799:GMET RS09885
gene id: 269799:GMET_RS09885
uniprot id: Q39U88
names: Similarity
messages: Belongs to the MEMO1 family.

269799:GMET RS07575
gene id: 269799:GMET_RS07575
uniprot id: Q39VI6
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

269799:GMET RS02160
gene id: 269799:GMET_RS02160
uniprot id: Q39YJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FlgA family.
messages: Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly.
messages: Periplasm

269799:GMET RS01960
gene id: 269799:GMET_RS01960
uniprot id: Q39YN8
names: Subcellular Location Annotation
messages: Membrane

269799:GMET RS08685
gene id: 269799:GMET_RS08685
uniprot id: Q39UW8
names: Similarity
messages: Belongs to the UPF0178 family.

269799:GMET RS11405
gene id: 269799:GMET_RS11405
uniprot id: Q39TD5
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

269799:GMET RS11700
gene id: 269799:GMET_RS11700
uniprot id: Q39T78
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

269799:GMET RS04695
gene id: 269799:GMET_RS04695
uniprot id: Q39X44
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

269799:GMET RS00360
gene id: 269799:GMET_RS00360
uniprot id: Q39ZK3
names: Function
names: Similarity
messages: Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).

269799:GMET RS10355
gene id: 269799:GMET_RS10355
uniprot id: Q39TZ3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Monomer.

269799:GMET RS00475
gene id: 269799:GMET_RS00475
uniprot id: Q39ZI0
names: Subcellular Location Annotation
messages: Nucleus

269799:GMET RS12710
gene id: 269799:GMET_RS12710
uniprot id: Q39SM4
names: Similarity
messages: Belongs to the peptidase M16 family.

269799:GMET RS04640
gene id: 269799:GMET_RS04640
uniprot id: Q39X55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Membrane

269799:GMET RS09200
gene id: 269799:GMET_RS09200
uniprot id: Q39UL8
names: Cofactor
names: Function
names: Subunit
messages: Binds 2 [4Fe-4S] clusters. In this family the first cluster has a non-standard and varying [4Fe-4S] binding motif CX(2)CX(2)CX(4-5)CP.
messages: Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates.
messages: Heterodimer of the IorA and IorB subunits.

269799:GMET RS16265
gene id: 269799:GMET_RS16265
uniprot id: Q39QL5
names: Cofactor
names: Function
messages: Binds 2 [4Fe-4S] clusters.
messages: Component of a complex that catalyzes the oxidation of glycolate to glyoxylate.

269799:GMET RS09525
gene id: 269799:GMET_RS09525
uniprot id: Q39UG0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.

269799:GMET RS11945
gene id: 269799:GMET_RS11945
uniprot id: Q39T29
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

269799:GMET RS16480
gene id: 269799:GMET_RS16480
uniprot id: Q39QH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

269799:GMET RS11825
gene id: 269799:GMET_RS11825
uniprot id: Q39T53
names: Similarity
messages: Belongs to the UPF0434 family.

269799:GMET RS16930
gene id: 269799:GMET_RS16930
uniprot id: Q39Q84
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LolB family.
messages: Cell outer membrane
messages: Membrane
messages: Monomer.

269799:GMET RS07260
gene id: 269799:GMET_RS07260
uniprot id: Q39VP9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

269799:GMET RS12310
gene id: 269799:GMET_RS12310
uniprot id: Q39SV4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Fur family.
messages: Cytoplasm
messages: Homodimer.

269799:GMET RS16100
gene id: 269799:GMET_RS16100
uniprot id: Q39QP8
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

269799:GMET RS08305
gene id: 269799:GMET_RS08305
uniprot id: Q39V42
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

269799:GMET RS13085
gene id: 269799:GMET_RS13085
uniprot id: Q39SE8
names: Function
names: Similarity
messages: Belongs to the LpxC family.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.

269799:GMET RS08060
gene id: 269799:GMET_RS08060
uniprot id: Q39V89
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

269799:GMET RS15080
gene id: 269799:GMET_RS15080
uniprot id: Q39RA1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

269799:GMET RS01660
gene id: 269799:GMET_RS01660
uniprot id: Q39YU9
names: Subcellular Location Annotation
messages: Membrane

269799:GMET RS09270
gene id: 269799:GMET_RS09270
uniprot id: Q39UK4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with NAD(+) as electron acceptor.
messages: Cytoplasm
messages: Heterotetramer of 2 PyrK and 2 PyrD type B subunits.

269799:GMET RS11720
gene id: 269799:GMET_RS11720
uniprot id: Q39T74
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

269799:GMET RS05395
gene id: 269799:GMET_RS05395
uniprot id: Q39WQ9
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

269799:GMET RS09010
gene id: 269799:GMET_RS09010
uniprot id: Q39WL7
names: Similarity
messages: Belongs to the transposase IS21/IS408/IS1162 family.

269799:GMET RS16755
gene id: 269799:GMET_RS16755
uniprot id: Q39QB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

269799:GMET RS02200
gene id: 269799:GMET_RS02200
uniprot id: Q39YJ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'-UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

269799:GMET RS05100
gene id: 269799:GMET_RS05100
uniprot id: Q39WW2
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

269799:GMET RS08300
gene id: 269799:GMET_RS08300
uniprot id: Q39V43
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

269799:GMET RS04100
gene id: 269799:GMET_RS04100
uniprot id: Q39XG3
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

269799:GMET RS08925
gene id: 269799:GMET_RS08925
uniprot id: Q39UR9
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

269799:GMET RS01690
gene id: 269799:GMET_RS01690
uniprot id: Q39YU3
names: Subcellular Location Annotation
messages: Membrane

269799:GMET RS16875
gene id: 269799:GMET_RS16875
uniprot id: Q39Q95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP G family.
messages: Cell inner membrane
messages: Membrane

269799:GMET RS00860
gene id: 269799:GMET_RS00860
uniprot id: Q39ZA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

269799:GMET RS05645
gene id: 269799:GMET_RS05645
uniprot id: Q39WK9
names: Similarity
messages: Belongs to the SfsA family.

269799:GMET RS03705
gene id: 269799:GMET_RS03705
uniprot id: Q39XP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

269799:GMET RS15800
gene id: 269799:GMET_RS15800
uniprot id: Q39QV8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. N-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

269799:GMET RS16300
gene id: 269799:GMET_RS16300
uniprot id: Q39QK8
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

269799:GMET RS03225
gene id: 269799:GMET_RS03225
uniprot id: Q39XZ1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

269799:GMET RS15255
gene id: 269799:GMET_RS15255
uniprot id: Q39R67
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

269799:GMET RS12610
gene id: 269799:GMET_RS12610
uniprot id: Q39SP3
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

269799:GMET RS01185
gene id: 269799:GMET_RS01185
uniprot id: Q39Z44
names: Similarity
messages: Belongs to the CvfB family.

269799:GMET RS04335
gene id: 269799:GMET_RS04335
uniprot id: Q39XB6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

269799:GMET RS03395
gene id: 269799:GMET_RS03395
uniprot id: Q39XV6
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

269799:GMET RS13235
gene id: 269799:GMET_RS13235
uniprot id: Q39SB7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.
messages: Cytoplasm
messages: Monomer.

269799:GMET RS07155
gene id: 269799:GMET_RS07155
uniprot id: Q39VS1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

269799:GMET RS02425
gene id: 269799:GMET_RS02425
uniprot id: Q39YE6
names: Function
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.

269799:GMET RS04765
gene id: 269799:GMET_RS04765
uniprot id: Q39X30
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

269799:GMET RS05385
gene id: 269799:GMET_RS05385
uniprot id: Q39WR1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

269799:GMET RS15395
gene id: 269799:GMET_RS15395
uniprot id: Q39R38
names: Similarity
messages: Belongs to the serine/threonine dehydratase family.

269799:GMET RS14070
gene id: 269799:GMET_RS14070
uniprot id: Q39RU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TamA family.
messages: Cell outer membrane
messages: Membrane

269799:GMET RS15805
gene id: 269799:GMET_RS15805
uniprot id: Q39QV7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

269799:GMET RS16080
gene id: 269799:GMET_RS16080
uniprot id: Q39QQ2
names: Function
names: Similarity
messages: Belongs to the CheD family.
messages: Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.

269799:GMET RS15210
gene id: 269799:GMET_RS15210
uniprot id: Q39R76
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruD family.
messages: Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.

269799:GMET RS10500
gene id: 269799:GMET_RS10500
uniprot id: Q39TW4
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

269799:GMET RS00800
gene id: 269799:GMET_RS00800
uniprot id: Q39ZB8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the complex I 75 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

269799:GMET RS05630
gene id: 269799:GMET_RS05630
uniprot id: Q39WL2
names: Similarity
messages: Belongs to the citrate synthase family.

269799:GMET RS05380
gene id: 269799:GMET_RS05380
uniprot id: Q39WR2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

269799:GMET RS17080
gene id: 269799:GMET_RS17080
uniprot id: Q39Q55
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

269799:GMET RS06900
gene id: 269799:GMET_RS06900
uniprot id: Q39VX0
names: Subcellular Location Annotation
messages: Membrane

269799:GMET RS04660
gene id: 269799:GMET_RS04660
uniprot id: Q39X51
names: Similarity
messages: Belongs to the peptidase S8 family.

269799:GMET RS17605
gene id: 269799:GMET_RS17605
uniprot id: Q39PV7
names: Function
names: Similarity
messages: In the C-terminal section; belongs to the aldehyde dehydrogenase family.
messages: In the N-terminal section; belongs to the proline dehydrogenase family.
messages: Oxidizes proline to glutamate for use as a carbon and nitrogen source.

269799:GMET RS06070
gene id: 269799:GMET_RS06070
uniprot id: Q39WD1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

269799:GMET RS10845
gene id: 269799:GMET_RS10845
uniprot id: Q39TP3
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

269799:GMET RS00955
gene id: 269799:GMET_RS00955
uniprot id: Q39Z88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

269799:GMET RS11420
gene id: 269799:GMET_RS11420
uniprot id: Q39TD2
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

269799:GMET RS06530
gene id: 269799:GMET_RS06530
uniprot id: Q39W41
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

269799:GMET RS00590
gene id: 269799:GMET_RS00590
uniprot id: Q39ZF8
names: Similarity
messages: Belongs to the HypD family.

269799:GMET RS11865
gene id: 269799:GMET_RS11865
uniprot id: Q39T45
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

269799:GMET RS17725
gene id: 269799:GMET_RS17725
uniprot id: Q39PT6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

269799:GMET RS17215
gene id: 269799:GMET_RS17215
uniprot id: Q39Q29
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

269799:GMET RS02185
gene id: 269799:GMET_RS02185
uniprot id: Q39YJ4
names: Function
names: Similarity
messages: Belongs to the FlgN family.
messages: Required for the efficient initiation of filament assembly.

269799:GMET RS02350
gene id: 269799:GMET_RS02350
uniprot id: Q39YG1
names: Domain
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the CobB/CbiA family.
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source.
messages: Comprises of two domains. The C-terminal domain contains the binding site for glutamine and catalyzes the hydrolysis of this substrate to glutamate and ammonia. The N-terminal domain is anticipated to bind ATP and cobyrinate and catalyzes the ultimate synthesis of the diamide product. The ammonia produced via the glutaminase domain is probably translocated to the adjacent domain via a molecular tunnel, where it reacts with an activated intermediate.
messages: The a and c carboxylates of cobyrinate are activated for nucleophilic attack via formation of a phosphorylated intermediate by ATP. CbiA catalyzes first the amidation of the c-carboxylate, and then that of the a-carboxylate.

269799:GMET RS02595
gene id: 269799:GMET_RS02595
uniprot id: Q39YB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Cell membrane
messages: Membrane

269799:GMET RS11560
gene id: 269799:GMET_RS11560
uniprot id: Q39TA6
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

269799:GMET RS09340
gene id: 269799:GMET_RS09340
uniprot id: Q39UJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell inner membrane
messages: Forms a membrane-associated complex with FtsE.
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in cellular division.

269799:GMET RS03125
gene id: 269799:GMET_RS03125
uniprot id: Q39Y12
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

269799:GMET RS06180
gene id: 269799:GMET_RS06180
uniprot id: Q39WB0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell inner membrane

269799:GMET RS13065
gene id: 269799:GMET_RS13065
uniprot id: Q39SF2
names: Function
names: Similarity
messages: Belongs to the PemK/MazF family.
messages: Toxic component of a type II toxin-antitoxin (TA) system.

269799:GMET RS15145
gene id: 269799:GMET_RS15145
uniprot id: Q39R89
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell inner membrane
messages: Probably interacts with PlsX.

269799:GMET RS08160
gene id: 269799:GMET_RS08160
uniprot id: Q39V69
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

269799:GMET RS10545
gene id: 269799:GMET_RS10545
uniprot id: Q39WR5
names: Function
names: Similarity
messages: Belongs to the transposase 11 family.
messages: Involved in the transposition of the insertion sequence IS5.

269799:GMET RS15185
gene id: 269799:GMET_RS15185
uniprot id: Q39R81
names: Similarity
messages: Belongs to the universal stress protein A family.

269799:GMET RS01825
gene id: 269799:GMET_RS01825
uniprot id: Q39YR5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

269799:GMET RS04490
gene id: 269799:GMET_RS04490
uniprot id: Q39X86
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

269799:GMET RS02180
gene id: 269799:GMET_RS02180
uniprot id: Q39YJ5
names: Function
names: Similarity
messages: Belongs to the FlgM family.
messages: Responsible for the coupling of flagellin expression to flagellar assembly by preventing expression of the flagellin genes when a component of the middle class of proteins is defective. It negatively regulates flagellar genes by inhibiting the activity of FliA by directly binding to FliA.

269799:GMET RS06450
gene id: 269799:GMET_RS06450
uniprot id: Q39W57
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptA family.
messages: Component of the lipopolysaccharide transport and assembly complex.
messages: Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane.
messages: Periplasm

269799:GMET RS11755
gene id: 269799:GMET_RS11755
uniprot id: Q39T67
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

269799:GMET RS04620
gene id: 269799:GMET_RS04620
uniprot id: Q39X59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gmhB family.
messages: Cytoplasm

269799:GMET RS06850
gene id: 269799:GMET_RS06850
uniprot id: Q39VY0
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 3 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

269799:GMET RS04630
gene id: 269799:GMET_RS04630
uniprot id: Q39X57
names: Function
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.

269799:GMET RS01800
gene id: 269799:GMET_RS01800
uniprot id: Q39YS0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

269799:GMET RS15455
gene id: 269799:GMET_RS15455
uniprot id: Q39R26
names: Subcellular Location Annotation
messages: Mitochondrion

269799:GMET RS16335
gene id: 269799:GMET_RS16335
uniprot id: Q39QK1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

269799:GMET RS14170
gene id: 269799:GMET_RS14170
uniprot id: Q39RS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Cell inner membrane

269799:GMET RS09575
gene id: 269799:GMET_RS09575
uniprot id: Q39UF1
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild-type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity.
messages: Belongs to the RecC family.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding.

269799:GMET RS02220
gene id: 269799:GMET_RS02220
uniprot id: Q39YI7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum
messages: Belongs to the FliD family.
messages: Homopentamer.
messages: Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
messages: Secreted

269799:GMET RS11785
gene id: 269799:GMET_RS11785
uniprot id: Q39T61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family.
messages: Membrane

269799:GMET RS02020
gene id: 269799:GMET_RS02020
uniprot id: Q39YM7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

269799:GMET RS12455
gene id: 269799:GMET_RS12455
uniprot id: Q39SS5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptD family.
messages: Cell outer membrane
messages: Component of the lipopolysaccharide transport and assembly complex.
messages: Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

269799:GMET RS13555
gene id: 269799:GMET_RS13555
uniprot id: Q39S52
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.
messages: Cell inner membrane
messages: Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

269799:GMET RS17745
gene id: 269799:GMET_RS17745
uniprot id: Q39PT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

269799:GMET RS15565
gene id: 269799:GMET_RS15565
uniprot id: Q39R05
names: Function
names: Similarity
messages: Belongs to the FlgD family.
messages: Required for flagellar hook formation. May act as a scaffolding protein.

269799:GMET RS00740
gene id: 269799:GMET_RS00740
uniprot id: Q39ZC8
names: Similarity
messages: Belongs to the glutamate synthase family.

269799:GMET RS06485
gene id: 269799:GMET_RS06485
uniprot id: Q39W50
names: Subcellular Location Annotation
messages: Cytoplasm

269799:GMET RS08805
gene id: 269799:GMET_RS08805
uniprot id: Q39UU3
names: Similarity
messages: Belongs to the peptidase S49 family.

269799:GMET RS03160
gene id: 269799:GMET_RS03160
uniprot id: Q39Y05
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

269799:GMET RS16120
gene id: 269799:GMET_RS16120
uniprot id: Q39QP4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell inner membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

269799:GMET RS01670
gene id: 269799:GMET_RS01670
uniprot id: Q39YU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
messages: Cell membrane
messages: Membrane

269799:GMET RS07570
gene id: 269799:GMET_RS07570
uniprot id: Q39VI7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

269799:GMET RS14770
gene id: 269799:GMET_RS14770
uniprot id: Q39RG4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

269799:GMET RS07085
gene id: 269799:GMET_RS07085
uniprot id: Q39VT3
names: Similarity
messages: Belongs to the ABC transporter superfamily.

269799:GMET RS07460
gene id: 269799:GMET_RS07460
uniprot id: Q39VK8
names: Similarity
messages: Belongs to the Lgt family.

269799:GMET RS06730
gene id: 269799:GMET_RS06730
uniprot id: Q39W02
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

269799:GMET RS04635
gene id: 269799:GMET_RS04635
uniprot id: Q39X56
names: Function
names: Similarity
messages: Belongs to the MreC family.
messages: Involved in formation and maintenance of cell shape.

269799:GMET RS15415
gene id: 269799:GMET_RS15415
uniprot id: Q39R34
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

269799:GMET RS11565
gene id: 269799:GMET_RS11565
uniprot id: Q39TA5
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

269799:GMET RS09275
gene id: 269799:GMET_RS09275
uniprot id: Q39UK3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PyrK family.
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Heterotetramer of 2 PyrK and 2 PyrD type B subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(+).

269799:GMET RS07025
gene id: 269799:GMET_RS07025
uniprot id: Q39VU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

269799:GMET RS12670
gene id: 269799:GMET_RS12670
uniprot id: Q39SN2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

269799:GMET RS11970
gene id: 269799:GMET_RS11970
uniprot id: Q39T24
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

269799:GMET RS05515
gene id: 269799:GMET_RS05515
uniprot id: Q39WN5
names: Similarity
messages: Belongs to the AlaDH/PNT family.

269799:GMET RS06565
gene id: 269799:GMET_RS06565
uniprot id: Q39W34
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

269799:GMET RS00940
gene id: 269799:GMET_RS00940
uniprot id: Q39Z91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0324 family.
messages: Membrane

269799:GMET RS02045
gene id: 269799:GMET_RS02045
uniprot id: Q39YM2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell inner membrane

269799:GMET RS15580
gene id: 269799:GMET_RS15580
uniprot id: Q39R02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliJ family.
messages: Cell membrane
messages: Membrane

269799:GMET RS02625
gene id: 269799:GMET_RS02625
uniprot id: Q39YA5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

269799:GMET RS13945
gene id: 269799:GMET_RS13945
uniprot id: Q39RX3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MetX family.
messages: Cytoplasm
messages: Homodimer.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

269799:GMET RS15470
gene id: 269799:GMET_RS15470
uniprot id: Q39R23
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

269799:GMET RS11880
gene id: 269799:GMET_RS11880
uniprot id: Q39T42
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamA family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

269799:GMET RS17865
gene id: 269799:GMET_RS17865
uniprot id: Q39PQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell inner membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

269799:GMET RS06315
gene id: 269799:GMET_RS06315
uniprot id: Q39W84
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

269799:GMET RS06285
gene id: 269799:GMET_RS06285
uniprot id: Q39W90
names: Subcellular Location Annotation
messages: Membrane

269799:GMET RS07215
gene id: 269799:GMET_RS07215
uniprot id: Q39VQ9
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily.

269799:GMET RS04700
gene id: 269799:GMET_RS04700
uniprot id: Q39X43
names: Function
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.
messages: DNA-dependent ATPase that plays important roles in cellular responses to stalled DNA replication processes.

269799:GMET RS01305
gene id: 269799:GMET_RS01305
uniprot id: Q39Z19
names: Similarity
messages: Belongs to the GSP E family.

269799:GMET RS01550
gene id: 269799:GMET_RS01550
uniprot id: Q39YX0
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

269799:GMET RS10160
gene id: 269799:GMET_RS10160
uniprot id: Q39U33
names: Subcellular Location Annotation
messages: Membrane

269799:GMET RS15235
gene id: 269799:GMET_RS15235
uniprot id: Q39R71
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

269799:GMET RS11985
gene id: 269799:GMET_RS11985
uniprot id: Q39T21
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

269799:GMET RS03505
gene id: 269799:GMET_RS03505
uniprot id: Q39XT4
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

269799:GMET RS12540
gene id: 269799:GMET_RS12540
uniprot id: Q39SQ9
names: Similarity
messages: Belongs to the TrpF family.

269799:GMET RS09440
gene id: 269799:GMET_RS09440
uniprot id: Q39UH3
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

269799:GMET RS03730
gene id: 269799:GMET_RS03730
uniprot id: Q39XN8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RuvC family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.

269799:GMET RS16885
gene id: 269799:GMET_RS16885
uniprot id: Q39Q93
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GSP I family.
messages: Cell inner membrane
messages: Cleaved by prepilin peptidase.
messages: Component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm.
messages: Type II secretion is composed of four main components: the outer membrane complex, the inner membrane complex, the cytoplasmic secretion ATPase and the periplasm-spanning pseudopilus.

269799:GMET RS17320
gene id: 269799:GMET_RS17320
uniprot id: Q39Q11
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

269799:GMET RS01300
gene id: 269799:GMET_RS01300
uniprot id: Q39Z20
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

269799:GMET RS10525
gene id: 269799:GMET_RS10525
uniprot id: Q39TV8
names: Similarity
messages: Belongs to the AOR/FOR family.

269799:GMET RS00285
gene id: 269799:GMET_RS00285
uniprot id: Q39ZL8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

269799:GMET RS00995
gene id: 269799:GMET_RS00995
uniprot id: Q39Z80
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

269799:GMET RS10745
gene id: 269799:GMET_RS10745
uniprot id: Q39TR3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell inner membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

269799:GMET RS00330
gene id: 269799:GMET_RS00330
uniprot id: Q39ZK9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Cytoplasm
messages: Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.

269799:GMET RS05785
gene id: 269799:GMET_RS05785
uniprot id: Q39WI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

269799:GMET RS07980
gene id: 269799:GMET_RS07980
uniprot id: Q39VA5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

269799:GMET RS04930
gene id: 269799:GMET_RS04930
uniprot id: Q39WZ7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

269799:GMET RS09635
gene id: 269799:GMET_RS09635
uniprot id: Q39UD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic sulfate-binding protein family.
messages: Periplasm

269799:GMET RS02210
gene id: 269799:GMET_RS02210
uniprot id: Q39YI9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

269799:GMET RS15125
gene id: 269799:GMET_RS15125
uniprot id: Q39R93
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell inner membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.

269799:GMET RS11430
gene id: 269799:GMET_RS11430
uniprot id: Q39TD0
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

269799:GMET RS16430
gene id: 269799:GMET_RS16430
uniprot id: Q39QI3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DksA family.
messages: Cytoplasm
messages: Interacts directly with the RNA polymerase.
messages: Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters.

269799:GMET RS05370
gene id: 269799:GMET_RS05370
uniprot id: Q39WR4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated exonuclease Cas4 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).
messages: Mg(2+) or Mn(2+) required for ssDNA cleavage activity.

269799:GMET RS13115
gene id: 269799:GMET_RS13115
uniprot id: Q39SE2
names: Similarity
names: Subunit
messages: Belongs to the desulfoferrodoxin family.
messages: Heterodimer of a large and a small subunit.

269799:GMET RS03310
gene id: 269799:GMET_RS03310
uniprot id: Q39XX3
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

269799:GMET RS02330
gene id: 269799:GMET_RS02330
uniprot id: Q39YG5
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

269799:GMET RS13545
gene id: 269799:GMET_RS13545
uniprot id: Q39S54
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

269799:GMET RS14945
gene id: 269799:GMET_RS14945
uniprot id: Q39RC9
names: Similarity
messages: Belongs to the YkuD family.

269799:GMET RS11615
gene id: 269799:GMET_RS11615
uniprot id: Q39T95
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

269799:GMET RS04460
gene id: 269799:GMET_RS04460
uniprot id: Q39X92
names: Similarity
messages: Belongs to the DprA/Smf family.

269799:GMET RS01025
gene id: 269799:GMET_RS01025
uniprot id: Q39Z74
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

269799:GMET RS06290
gene id: 269799:GMET_RS06290
uniprot id: Q39W89
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

269799:GMET RS17750
gene id: 269799:GMET_RS17750
uniprot id: Q39PT1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

269799:GMET RS01010
gene id: 269799:GMET_RS01010
uniprot id: Q39Z77
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

269799:GMET RS06610
gene id: 269799:GMET_RS06610
uniprot id: Q39W27
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.
messages: Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

269799:GMET RS03210
gene id: 269799:GMET_RS03210
uniprot id: Q39XZ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

269799:GMET RS09795
gene id: 269799:GMET_RS09795
uniprot id: Q39UA6
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

269799:GMET RS03140
gene id: 269799:GMET_RS03140
uniprot id: Q39Y09
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

269799:GMET RS12175
gene id: 269799:GMET_RS12175
uniprot id: Q39SY1
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

269799:GMET RS11990
gene id: 269799:GMET_RS11990
uniprot id: Q39T20
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide.

269799:GMET RS09515
gene id: 269799:GMET_RS09515
uniprot id: Q39UG2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

269799:GMET RS16025
gene id: 269799:GMET_RS16025
uniprot id: Q39QR3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

269799:GMET RS04585
gene id: 269799:GMET_RS04585
uniprot id: Q39X66
names: Similarity
messages: Belongs to the SAICAR synthetase family.

269799:GMET RS04225
gene id: 269799:GMET_RS04225
uniprot id: Q39XD8
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily.
messages: Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway.

269799:GMET RS05860
gene id: 269799:GMET_RS05860
uniprot id: Q39WG7
names: Similarity
messages: Belongs to the peptidase C40 family.

269799:GMET RS11045
gene id: 269799:GMET_RS11045
uniprot id: Q39TK4
names: Similarity
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

269799:GMET RS16065
gene id: 269799:GMET_RS16065
uniprot id: Q39QQ5
names: Similarity
messages: Belongs to the UPF0234 family.

269799:GMET RS16785
gene id: 269799:GMET_RS16785
uniprot id: Q39QB3
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

269799:GMET RS05810
gene id: 269799:GMET_RS05810
uniprot id: Q39WH7
names: Similarity
messages: Belongs to the UDPGP type 2 family.

269799:GMET RS04280
gene id: 269799:GMET_RS04280
uniprot id: Q39XC7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

269799:GMET RS13470
gene id: 269799:GMET_RS13470
uniprot id: Q39S71
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.

269799:GMET RS08155
gene id: 269799:GMET_RS08155
uniprot id: Q39V70
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

269799:GMET RS13765
gene id: 269799:GMET_RS13765
uniprot id: Q39S10
names: Similarity
messages: Belongs to the peptidase S16 family.

269799:GMET RS12450
gene id: 269799:GMET_RS12450
uniprot id: Q39SS6
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

269799:GMET RS01810
gene id: 269799:GMET_RS01810
uniprot id: Q39YR8
names: Domain
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

269799:GMET RS02430
gene id: 269799:GMET_RS02430
uniprot id: Q39YE5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobD/CbiB family.
messages: Cell membrane
messages: Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.

269799:GMET RS17665
gene id: 269799:GMET_RS17665
uniprot id: Q39PU5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

269799:GMET RS17870
gene id: 269799:GMET_RS17870
uniprot id: Q39PQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell inner membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

269799:GMET RS12545
gene id: 269799:GMET_RS12545
uniprot id: Q39SQ8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

269799:GMET RS06460
gene id: 269799:GMET_RS06460
uniprot id: Q39W55
names: Function
names: Similarity
messages: Belongs to the sigma-54 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

269799:GMET RS03165
gene id: 269799:GMET_RS03165
uniprot id: Q39Y04
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

269799:GMET RS12595
gene id: 269799:GMET_RS12595
uniprot id: Q39SP6
names: Subcellular Location Annotation
messages: Membrane

269799:GMET RS11410
gene id: 269799:GMET_RS11410
uniprot id: Q39TD4
names: Subcellular Location Annotation
messages: Membrane

269799:GMET RS01020
gene id: 269799:GMET_RS01020
uniprot id: Q39Z75
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

269799:GMET RS13215
gene id: 269799:GMET_RS13215
uniprot id: Q39SC1
names: Subcellular Location Annotation
messages: Membrane

269799:GMET RS06125
gene id: 269799:GMET_RS06125
uniprot id: Q39WC0
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

269799:GMET RS16945
gene id: 269799:GMET_RS16945
uniprot id: Q39Q81
names: Function
names: Similarity
messages: Belongs to the PNP/UDP phosphorylase family. Futalosine hydrolase subfamily.
messages: Catalyzes the hydrolysis of futalosine (FL) to dehypoxanthine futalosine (DHFL) and hypoxanthine, a step in the biosynthesis of menaquinone (MK, vitamin K2).

269799:GMET RS09590
gene id: 269799:GMET_RS09590
uniprot id: Q39UE8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRA-CH family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
messages: Cytoplasm
messages: Homodimer.

269799:GMET RS09085
gene id: 269799:GMET_RS09085
uniprot id: Q39UP1
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

269799:GMET RS01510
gene id: 269799:GMET_RS01510
uniprot id: Q39YX8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

269799:GMET RS13050
gene id: 269799:GMET_RS13050
uniprot id: Q39SF5
names: Subcellular Location Annotation
messages: Membrane

269799:GMET RS01250
gene id: 269799:GMET_RS01250
uniprot id: Q39Z30
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
messages: Membrane

269799:GMET RS08255
gene id: 269799:GMET_RS08255
uniprot id: Q39V50
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

269799:GMET RS16690
gene id: 269799:GMET_RS16690
uniprot id: Q39QD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HupC/HyaC/HydC family.
messages: Membrane

269799:GMET RS08005
gene id: 269799:GMET_RS08005
uniprot id: Q39VA0
names: Similarity
messages: Belongs to the peptidase M16 family.

269799:GMET RS17510
gene id: 269799:GMET_RS17510
uniprot id: Q39PX7
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

269799:GMET RS12845
gene id: 269799:GMET_RS12845
uniprot id: Q39SJ7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

269799:GMET RS01705
gene id: 269799:GMET_RS01705
uniprot id: Q39YT9
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

269799:GMET RS17075
gene id: 269799:GMET_RS17075
uniprot id: Q39Q56
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

269799:GMET RS12800
gene id: 269799:GMET_RS12800
uniprot id: Q39SK6
names: Similarity
messages: Belongs to the AdoMet synthetase 2 family.

269799:GMET RS01860
gene id: 269799:GMET_RS01860
uniprot id: Q39YQ8
names: Subcellular Location Annotation
messages: Membrane

269799:GMET RS04360
gene id: 269799:GMET_RS04360
uniprot id: Q39XB2
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

269799:GMET RS05765
gene id: 269799:GMET_RS05765
uniprot id: Q39WI6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbC subfamily.
messages: Periplasm
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process.

269799:GMET RS17860
gene id: 269799:GMET_RS17860
uniprot id: Q39PQ9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.

269799:GMET RS17560
gene id: 269799:GMET_RS17560
uniprot id: Q39PW6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the threonine aldolase family.
messages: Catalyzes the cleavage of L-allo-threonine and L-threonine to glycine and acetaldehyde.
messages: Homotetramer.

269799:GMET RS14605
gene id: 269799:GMET_RS14605
uniprot id: Q39RJ6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
messages: Homodimer.

269799:GMET RS00780
gene id: 269799:GMET_RS00780
uniprot id: Q39ZC2
names: Similarity
messages: Belongs to the cytochrome c family. PetJ subfamily.

269799:GMET RS13865
gene id: 269799:GMET_RS13865
uniprot id: Q39RZ0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

269799:GMET RS16635
gene id: 269799:GMET_RS16635
uniprot id: Q39QE2
names: Subcellular Location Annotation
messages: Periplasm

269799:GMET RS08615
gene id: 269799:GMET_RS08615
uniprot id: Q39UY1
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

269799:GMET RS17765
gene id: 269799:GMET_RS17765
uniprot id: Q39PS8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Pal lipoprotein family.
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

269799:GMET RS03235
gene id: 269799:GMET_RS03235
uniprot id: Q39XY9
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

269799:GMET RS14365
gene id: 269799:GMET_RS14365
uniprot id: Q39RP4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

269799:GMET RS09330
gene id: 269799:GMET_RS09330
uniprot id: Q39UJ2
names: Similarity
messages: Belongs to the peptidase S41A family.

269799:GMET RS06570
gene id: 269799:GMET_RS06570
uniprot id: Q39W33
names: Similarity
messages: Belongs to the ros/MucR family.

269799:GMET RS08635
gene id: 269799:GMET_RS08635
uniprot id: Q39UX7
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

269799:GMET RS05565
gene id: 269799:GMET_RS05565
uniprot id: Q39WM5
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.