269798:CHU RS17935
gene id: 269798:CHU_RS17935
uniprot id: A0A6N4SX75
names: Similarity
messages: Belongs to the asparagine synthetase family.

269798:CHU RS00965
gene id: 269798:CHU_RS00965
uniprot id: Q11YP0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

269798:CHU RS05645
gene id: 269798:CHU_RS05645
uniprot id: A0A6N4SQ61
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

269798:CHU RS00960
gene id: 269798:CHU_RS00960
uniprot id: Q11YP1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

269798:CHU RS12770
gene id: 269798:CHU_RS12770
uniprot id: Q11RT7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

269798:CHU RS01825
gene id: 269798:CHU_RS01825
uniprot id: A0A6N4SN18
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

269798:CHU RS14655
gene id: 269798:CHU_RS14655
uniprot id: A0A6N4SV19
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

269798:CHU RS08070
gene id: 269798:CHU_RS08070
uniprot id: A0A6N4SRJ2
names: Similarity
messages: Belongs to the peptidase C40 family.

269798:CHU RS15585
gene id: 269798:CHU_RS15585
uniprot id: A0A6N4SVY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell membrane
messages: Membrane

269798:CHU RS14560
gene id: 269798:CHU_RS14560
uniprot id: A0A6N4SUT2
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

269798:CHU RS17325
gene id: 269798:CHU_RS17325
uniprot id: A0A6N4SW09
names: Subcellular Location Annotation
messages: Membrane

269798:CHU RS10565
gene id: 269798:CHU_RS10565
uniprot id: A0A6N4ST14
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

269798:CHU RS00370
gene id: 269798:CHU_RS00370
uniprot id: A0A6N4SM92
names: Similarity
names: Subunit
messages: Homotetramer.
messages: In the C-terminal section; belongs to the homoserine dehydrogenase family.
messages: In the N-terminal section; belongs to the aspartokinase family.

269798:CHU RS01660
gene id: 269798:CHU_RS01660
uniprot id: A0A6N4SMY7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MenA family. Type 1 subfamily.
messages: Cell inner membrane
messages: Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK).
messages: Membrane

269798:CHU RS10830
gene id: 269798:CHU_RS10830
uniprot id: A0A6N4ST45
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

269798:CHU RS11765
gene id: 269798:CHU_RS11765
uniprot id: A0A6N4STN3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell inner membrane

269798:CHU RS08075
gene id: 269798:CHU_RS08075
uniprot id: A0A6N4SRF8
names: Similarity
messages: Belongs to the DEAD box helicase family.

269798:CHU RS16035
gene id: 269798:CHU_RS16035
uniprot id: A0A6N4SW65
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

269798:CHU RS08480
gene id: 269798:CHU_RS08480
uniprot id: A0A6N4SRR4
names: Similarity
messages: Belongs to the glutamine synthetase family.

269798:CHU RS15565
gene id: 269798:CHU_RS15565
uniprot id: A0A6N4SV90
names: Similarity
messages: Belongs to the bacterial secretin family.

269798:CHU RS18130
gene id: 269798:CHU_RS18130
uniprot id: A0A6N4SWM5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

269798:CHU RS12985
gene id: 269798:CHU_RS12985
uniprot id: Q11RP5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

269798:CHU RS11865
gene id: 269798:CHU_RS11865
uniprot id: A0A6N4SU04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

269798:CHU RS16440
gene id: 269798:CHU_RS16440
uniprot id: A0A6N4SVM9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the 3-HAO family.
messages: Binds 2 Fe(2+) ions per subunit.
messages: Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate.

269798:CHU RS04500
gene id: 269798:CHU_RS04500
uniprot id: A0A6N4SPL4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

269798:CHU RS17880
gene id: 269798:CHU_RS17880
uniprot id: A0A6N4SXD7
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

269798:CHU RS15355
gene id: 269798:CHU_RS15355
uniprot id: Q11QB6
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

269798:CHU RS05110
gene id: 269798:CHU_RS05110
uniprot id: A0A6N4SPQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

269798:CHU RS05975
gene id: 269798:CHU_RS05975
uniprot id: A0A6N4SQ73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

269798:CHU RS09790
gene id: 269798:CHU_RS09790
uniprot id: Q11TJ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate.
messages: Homotrimer.

269798:CHU RS05590
gene id: 269798:CHU_RS05590
uniprot id: Q11VZ3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.

269798:CHU RS09390
gene id: 269798:CHU_RS09390
uniprot id: A0A6N4SS83
names: Subunit
messages: Homodimer.

269798:CHU RS08120
gene id: 269798:CHU_RS08120
uniprot id: A0A6N4SRE3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: In the N-terminal section; belongs to the FGAMS family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.

269798:CHU RS05230
gene id: 269798:CHU_RS05230
uniprot id: Q11W68
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TER reductase family.
messages: Involved in the final reduction of the elongation cycle of fatty acid synthesis (FAS II). Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP).
messages: Monomer.

269798:CHU RS13655
gene id: 269798:CHU_RS13655
uniprot id: A0A6N4SU88
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

269798:CHU RS02435
gene id: 269798:CHU_RS02435
uniprot id: A0A6N4SNB3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL31 family.

269798:CHU RS00605
gene id: 269798:CHU_RS00605
uniprot id: Q11YV4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

269798:CHU RS10735
gene id: 269798:CHU_RS10735
uniprot id: A0A6N4SSV5
names: Similarity
messages: Belongs to the SCO1/2 family.

269798:CHU RS02965
gene id: 269798:CHU_RS02965
uniprot id: Q11XI0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

269798:CHU RS06735
gene id: 269798:CHU_RS06735
uniprot id: A0A6N4SQN9
names: Subcellular Location Annotation
messages: Membrane

269798:CHU RS04025
gene id: 269798:CHU_RS04025
uniprot id: A0A6N4SPA1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

269798:CHU RS06380
gene id: 269798:CHU_RS06380
uniprot id: A0A6N4SQG9
names: Function
messages: Might have a role analogous to that of eukaryotic histone proteins.

269798:CHU RS02790
gene id: 269798:CHU_RS02790
uniprot id: A0A6N4SNJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0324 family.
messages: Membrane

269798:CHU RS00600
gene id: 269798:CHU_RS00600
uniprot id: Q11YV5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein S19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein S19.

269798:CHU RS04505
gene id: 269798:CHU_RS04505
uniprot id: A0A6N4SPF1
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

269798:CHU RS17730
gene id: 269798:CHU_RS17730
uniprot id: A0A6N4SX15
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

269798:CHU RS03210
gene id: 269798:CHU_RS03210
uniprot id: A0A6N4SNR8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell inner membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

269798:CHU RS08650
gene id: 269798:CHU_RS08650
uniprot id: A0A6N4SRL8
names: Subcellular Location Annotation
messages: Membrane

269798:CHU RS10040
gene id: 269798:CHU_RS10040
uniprot id: A0A6N4SSY0
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

269798:CHU RS18405
gene id: 269798:CHU_RS18405
uniprot id: A0A6N4SXV3
names: Similarity
messages: Belongs to the AHA1 family.

269798:CHU RS15305
gene id: 269798:CHU_RS15305
uniprot id: Q11QC6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

269798:CHU RS04580
gene id: 269798:CHU_RS04580
uniprot id: A0A6N4SPJ6
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

269798:CHU RS07355
gene id: 269798:CHU_RS07355
uniprot id: A0A6N4SR06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

269798:CHU RS18585
gene id: 269798:CHU_RS18585
uniprot id: A0A6N4SXF0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

269798:CHU RS18365
gene id: 269798:CHU_RS18365
uniprot id: A0A6N4SWK4
names: Similarity
messages: Belongs to the HipA Ser/Thr kinase family.

269798:CHU RS17425
gene id: 269798:CHU_RS17425
uniprot id: A0A6N4SW23
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

269798:CHU RS08860
gene id: 269798:CHU_RS08860
uniprot id: A0A6N4SRQ7
names: Similarity
messages: Belongs to the CvfB family.

269798:CHU RS12715
gene id: 269798:CHU_RS12715
uniprot id: A0A6N4STU2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell inner membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

269798:CHU RS01730
gene id: 269798:CHU_RS01730
uniprot id: A0A6N4SMY3
names: Similarity
messages: Belongs to the pirin family.

269798:CHU RS16340
gene id: 269798:CHU_RS16340
uniprot id: A0A6N4SVK8
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

269798:CHU RS15575
gene id: 269798:CHU_RS15575
uniprot id: A0A6N4SVN5
names: Similarity
messages: Belongs to the peptidase A24 family.

269798:CHU RS06375
gene id: 269798:CHU_RS06375
uniprot id: A0A6N4SQL6
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

269798:CHU RS12430
gene id: 269798:CHU_RS12430
uniprot id: A0A6N4SU23
names: Similarity
messages: Belongs to the AHA1 family.

269798:CHU RS04880
gene id: 269798:CHU_RS04880
uniprot id: A0A6N4SPP0
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

269798:CHU RS00590
gene id: 269798:CHU_RS00590
uniprot id: A0A6N4SMC6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

269798:CHU RS03755
gene id: 269798:CHU_RS03755
uniprot id: A0A6N4SP08
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

269798:CHU RS15490
gene id: 269798:CHU_RS15490
uniprot id: Q11Q93
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).

269798:CHU RS13905
gene id: 269798:CHU_RS13905
uniprot id: A0A6N4SV25
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

269798:CHU RS00485
gene id: 269798:CHU_RS00485
uniprot id: A0A6N4SMA6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

269798:CHU RS06520
gene id: 269798:CHU_RS06520
uniprot id: A0A6N4SQH4
names: Similarity
messages: Belongs to the YjdM family.

269798:CHU RS02805
gene id: 269798:CHU_RS02805
uniprot id: A0A6N4SNM7
names: Subcellular Location Annotation
messages: Membrane

269798:CHU RS17620
gene id: 269798:CHU_RS17620
uniprot id: Q11P01
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

269798:CHU RS03250
gene id: 269798:CHU_RS03250
uniprot id: A0A6N4SNR5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

269798:CHU RS04730
gene id: 269798:CHU_RS04730
uniprot id: Q11WG7
names: Similarity
messages: Belongs to the UPF0403 family.

269798:CHU RS15300
gene id: 269798:CHU_RS15300
uniprot id: Q11QC7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

269798:CHU RS09490
gene id: 269798:CHU_RS09490
uniprot id: A0A6N4SSA4
names: Similarity
messages: Belongs to the deoxyhypusine synthase family.

269798:CHU RS16400
gene id: 269798:CHU_RS16400
uniprot id: Q11PQ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Monomer.

269798:CHU RS16330
gene id: 269798:CHU_RS16330
uniprot id: A0A6N4SVY4
names: Subcellular Location Annotation
messages: Membrane

269798:CHU RS13530
gene id: 269798:CHU_RS13530
uniprot id: A0A6N4SUM7
names: Subcellular Location Annotation
messages: Cell inner membrane

269798:CHU RS07930
gene id: 269798:CHU_RS07930
uniprot id: A0A6N4SRJ3
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

269798:CHU RS15810
gene id: 269798:CHU_RS15810
uniprot id: A0A6N4SVC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmC/CycZ/HelC family.
messages: Membrane

269798:CHU RS14980
gene id: 269798:CHU_RS14980
uniprot id: A0A6N4SV85
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

269798:CHU RS12120
gene id: 269798:CHU_RS12120
uniprot id: A0A6N4STN5
names: Subcellular Location Annotation
messages: Membrane

269798:CHU RS07720
gene id: 269798:CHU_RS07720
uniprot id: Q11UQ9
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

269798:CHU RS07635
gene id: 269798:CHU_RS07635
uniprot id: A0A6N4SR77
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

269798:CHU RS13335
gene id: 269798:CHU_RS13335
uniprot id: Q11RH2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell inner membrane

269798:CHU RS16645
gene id: 269798:CHU_RS16645
uniprot id: A0A6N4SVN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

269798:CHU RS05250
gene id: 269798:CHU_RS05250
uniprot id: A0A6N4SPX0
names: Similarity
messages: Belongs to the glycosyl hydrolase 8 (cellulase D) family.

269798:CHU RS14245
gene id: 269798:CHU_RS14245
uniprot id: A0A6N4SVA3
names: Similarity
messages: Belongs to the HsdR family.

269798:CHU RS13740
gene id: 269798:CHU_RS13740
uniprot id: A0A6N4SUT0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

269798:CHU RS04760
gene id: 269798:CHU_RS04760
uniprot id: A0A6N4SPI8
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

269798:CHU RS15080
gene id: 269798:CHU_RS15080
uniprot id: Q11QH3
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

269798:CHU RS12295
gene id: 269798:CHU_RS12295
uniprot id: Q11S34
names: Similarity
messages: Belongs to the CinA family.

269798:CHU RS13925
gene id: 269798:CHU_RS13925
uniprot id: A0A6N4SUF3
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

269798:CHU RS02305
gene id: 269798:CHU_RS02305
uniprot id: A0A6N4SN95
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

269798:CHU RS16605
gene id: 269798:CHU_RS16605
uniprot id: A0A6N4SW25
names: Similarity
messages: Belongs to the Skp family.

269798:CHU RS14530
gene id: 269798:CHU_RS14530
uniprot id: Q11QT3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
messages: Belongs to the ClpX chaperone family. HslU subfamily.
messages: Cytoplasm

269798:CHU RS06750
gene id: 269798:CHU_RS06750
uniprot id: A0A6N4SQL2
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily.
messages: Binds 1 NADP(+) per subunit.
messages: Catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose.
messages: Contains a large N-terminal NADP-binding domain, and a smaller C-terminal substrate-binding domain.
messages: Homopentamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

269798:CHU RS07935
gene id: 269798:CHU_RS07935
uniprot id: A0A6N4SR86
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

269798:CHU RS07890
gene id: 269798:CHU_RS07890
uniprot id: A0A6N4SRG7
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

269798:CHU RS02865
gene id: 269798:CHU_RS02865
uniprot id: Q11XK1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

269798:CHU RS13770
gene id: 269798:CHU_RS13770
uniprot id: A0A6N4SUJ2
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

269798:CHU RS15710
gene id: 269798:CHU_RS15710
uniprot id: A0A6N4SVH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

269798:CHU RS07045
gene id: 269798:CHU_RS07045
uniprot id: A0A6N4SQW3
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

269798:CHU RS18615
gene id: 269798:CHU_RS18615
uniprot id: A0A6N4SX56
names: Subcellular Location Annotation
messages: Membrane

269798:CHU RS08510
gene id: 269798:CHU_RS08510
uniprot id: Q11UA6
names: Similarity
names: Subunit
messages: Belongs to the glutaminase family.
messages: Homotetramer.

269798:CHU RS11900
gene id: 269798:CHU_RS11900
uniprot id: A0A6N4STJ2
names: Similarity
messages: Belongs to the NusB family.

269798:CHU RS04605
gene id: 269798:CHU_RS04605
uniprot id: A0A6N4SPM0
names: Similarity
messages: Belongs to the ribF family.

269798:CHU RS03370
gene id: 269798:CHU_RS03370
uniprot id: A0A6N4SNY4
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

269798:CHU RS12310
gene id: 269798:CHU_RS12310
uniprot id: Q11S31
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 3B subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

269798:CHU RS06885
gene id: 269798:CHU_RS06885
uniprot id: A0A6N4SQW2
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

269798:CHU RS00645
gene id: 269798:CHU_RS00645
uniprot id: A0A6N4SMC7
names: Similarity
messages: Belongs to the AIR synthase family.

269798:CHU RS06180
gene id: 269798:CHU_RS06180
uniprot id: Q11VM5
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

269798:CHU RS08685
gene id: 269798:CHU_RS08685
uniprot id: A0A6N4SRS4
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Homodimer.

269798:CHU RS18645
gene id: 269798:CHU_RS18645
uniprot id: A0A6N4SXG9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Cell membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

269798:CHU RS15395
gene id: 269798:CHU_RS15395
uniprot id: Q11QA8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

269798:CHU RS07810
gene id: 269798:CHU_RS07810
uniprot id: A0A6N4SR98
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

269798:CHU RS15475
gene id: 269798:CHU_RS15475
uniprot id: A0A6N4SVW6
names: Similarity
messages: Belongs to the sigma-54 factor family.

269798:CHU RS06140
gene id: 269798:CHU_RS06140
uniprot id: Q11VN3
names: Cofactor
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
messages: Binds 2 nickel ions per subunit.
messages: Carboxylation allows a single lysine to coordinate two nickel ions.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

269798:CHU RS01715
gene id: 269798:CHU_RS01715
uniprot id: A0A6N4SMX5
names: Similarity
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.

269798:CHU RS04010
gene id: 269798:CHU_RS04010
uniprot id: A0A6N4SP82
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

269798:CHU RS07840
gene id: 269798:CHU_RS07840
uniprot id: Q11UN5
names: Similarity
messages: Belongs to the DNA glycosylase MPG family.

269798:CHU RS06855
gene id: 269798:CHU_RS06855
uniprot id: A0A6N4SQN3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

269798:CHU RS08310
gene id: 269798:CHU_RS08310
uniprot id: Q11UE6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

269798:CHU RS05970
gene id: 269798:CHU_RS05970
uniprot id: A0A6N4SQF7
names: Cofactor
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

269798:CHU RS09260
gene id: 269798:CHU_RS09260
uniprot id: A0A6N4SS61
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

269798:CHU RS10810
gene id: 269798:CHU_RS10810
uniprot id: A0A6N4SSX1
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

269798:CHU RS18015
gene id: 269798:CHU_RS18015
uniprot id: A0A6N4SWK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

269798:CHU RS10835
gene id: 269798:CHU_RS10835
uniprot id: A0A6N4SSS3
names: Subcellular Location Annotation
messages: Nucleus

269798:CHU RS07665
gene id: 269798:CHU_RS07665
uniprot id: A0A6N4SRC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gmhB family.
messages: Cytoplasm

269798:CHU RS05485
gene id: 269798:CHU_RS05485
uniprot id: Q11W14
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase Y family.
messages: Cell membrane
messages: Endoribonuclease that initiates mRNA decay.

269798:CHU RS07540
gene id: 269798:CHU_RS07540
uniprot id: A0A6N4SR58
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

269798:CHU RS13245
gene id: 269798:CHU_RS13245
uniprot id: A0A6N4SU19
names: Similarity
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.

269798:CHU RS18830
gene id: 269798:CHU_RS18830
uniprot id: A0A6N4SQ80
names: Similarity
messages: Belongs to the glycosyl hydrolase 8 (cellulase D) family.

269798:CHU RS14205
gene id: 269798:CHU_RS14205
uniprot id: A0A6N4SV15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

269798:CHU RS00850
gene id: 269798:CHU_RS00850
uniprot id: A0A6N4SMG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

269798:CHU RS03140
gene id: 269798:CHU_RS03140
uniprot id: A0A6N4SNP9
names: Similarity
messages: Belongs to the PAPS reductase family. CysD subfamily.

269798:CHU RS02960
gene id: 269798:CHU_RS02960
uniprot id: Q11XI1
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

269798:CHU RS09110
gene id: 269798:CHU_RS09110
uniprot id: A0A6N4SRW2
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

269798:CHU RS01550
gene id: 269798:CHU_RS01550
uniprot id: A0A6N4SMT9
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

269798:CHU RS09050
gene id: 269798:CHU_RS09050
uniprot id: Q11TZ6
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

269798:CHU RS13190
gene id: 269798:CHU_RS13190
uniprot id: A0A6N4SUQ4
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).

269798:CHU RS11420
gene id: 269798:CHU_RS11420
uniprot id: A0A6N4ST15
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 2 residues (Tyr-53 and Arg-56) present in a large hydrophobic pocket are probably involved in substrate specificity. They are important for desuccinylation activity, but dispensable for deacetylation activity.
messages: Belongs to the sirtuin family. Class III subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form.

269798:CHU RS01415
gene id: 269798:CHU_RS01415
uniprot id: A0A6N4SMR6
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

269798:CHU RS15290
gene id: 269798:CHU_RS15290
uniprot id: Q11QC9
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

269798:CHU RS06120
gene id: 269798:CHU_RS06120
uniprot id: A0A6N4SQA6
names: Subcellular Location Annotation
messages: Membrane

269798:CHU RS10505
gene id: 269798:CHU_RS10505
uniprot id: A0A6N4SSN4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

269798:CHU RS03025
gene id: 269798:CHU_RS03025
uniprot id: A0A6N4SNP5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein L14 (rplN).

269798:CHU RS03400
gene id: 269798:CHU_RS03400
uniprot id: A0A6N4SNT7
names: Subcellular Location Annotation
messages: Cytoplasm

269798:CHU RS06680
gene id: 269798:CHU_RS06680
uniprot id: Q11VC2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

269798:CHU RS15345
gene id: 269798:CHU_RS15345
uniprot id: Q11QB8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

269798:CHU RS09575
gene id: 269798:CHU_RS09575
uniprot id: A0A6N4SSC7
names: Subcellular Location Annotation
messages: Membrane

269798:CHU RS02410
gene id: 269798:CHU_RS02410
uniprot id: A0A6N4SNC0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

269798:CHU RS08930
gene id: 269798:CHU_RS08930
uniprot id: A0A6N4SRS2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

269798:CHU RS03220
gene id: 269798:CHU_RS03220
uniprot id: Q11XC6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
messages: Cytoplasm

269798:CHU RS06930
gene id: 269798:CHU_RS06930
uniprot id: A0A6N4SQW9
names: Similarity
messages: Belongs to the AHA1 family.

269798:CHU RS18185
gene id: 269798:CHU_RS18185
uniprot id: Q11NN8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

269798:CHU RS09795
gene id: 269798:CHU_RS09795
uniprot id: A0A6N4SSF3
names: Subcellular Location Annotation
messages: Membrane

269798:CHU RS15350
gene id: 269798:CHU_RS15350
uniprot id: Q11QB7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity).

269798:CHU RS13695
gene id: 269798:CHU_RS13695
uniprot id: Q11RA1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

269798:CHU RS17360
gene id: 269798:CHU_RS17360
uniprot id: A0A6N4SW88
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

269798:CHU RS06655
gene id: 269798:CHU_RS06655
uniprot id: A0A6N4SQP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

269798:CHU RS11880
gene id: 269798:CHU_RS11880
uniprot id: A0A6N4STK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

269798:CHU RS09105
gene id: 269798:CHU_RS09105
uniprot id: A0A6N4SS21
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 4 family.

269798:CHU RS08590
gene id: 269798:CHU_RS08590
uniprot id: Q11U88
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TPP enzyme family. MenD subfamily.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
messages: Homodimer.

269798:CHU RS05810
gene id: 269798:CHU_RS05810
uniprot id: Q11VU7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

269798:CHU RS03195
gene id: 269798:CHU_RS03195
uniprot id: A0A6N4SNS6
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

269798:CHU RS09920
gene id: 269798:CHU_RS09920
uniprot id: A0A6N4SS80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

269798:CHU RS08115
gene id: 269798:CHU_RS08115
uniprot id: A0A6N4SRJ9
names: Similarity
messages: Belongs to the pirin family.

269798:CHU RS16020
gene id: 269798:CHU_RS16020
uniprot id: A0A6N4SVS6
names: Similarity
messages: Belongs to the TrpC family.

269798:CHU RS07250
gene id: 269798:CHU_RS07250
uniprot id: A0A6N4SQV6
names: Similarity
messages: Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family.

269798:CHU RS10850
gene id: 269798:CHU_RS10850
uniprot id: A0A6N4SSZ9
names: Subcellular Location Annotation
messages: Mitochondrion

269798:CHU RS13885
gene id: 269798:CHU_RS13885
uniprot id: A0A6N4SUF9
names: Function
messages: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.

269798:CHU RS06185
gene id: 269798:CHU_RS06185
uniprot id: A0A6N4SQI6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: In the N-terminal section; belongs to the histidinol-phosphatase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

269798:CHU RS07925
gene id: 269798:CHU_RS07925
uniprot id: A0A6N4SRC0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

269798:CHU RS13315
gene id: 269798:CHU_RS13315
uniprot id: Q11RH6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

269798:CHU RS05195
gene id: 269798:CHU_RS05195
uniprot id: A0A6N4SPV3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

269798:CHU RS08320
gene id: 269798:CHU_RS08320
uniprot id: A0A6N4SRN5
names: Similarity
messages: Belongs to the Fur family.

269798:CHU RS03410
gene id: 269798:CHU_RS03410
uniprot id: Q11X86
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

269798:CHU RS07895
gene id: 269798:CHU_RS07895
uniprot id: A0A6N4SRD1
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

269798:CHU RS12780
gene id: 269798:CHU_RS12780
uniprot id: A0A6N4STV3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

269798:CHU RS01210
gene id: 269798:CHU_RS01210
uniprot id: A0A6N4SMQ1
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

269798:CHU RS17790
gene id: 269798:CHU_RS17790
uniprot id: A0A6N4SWC1
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

269798:CHU RS18320
gene id: 269798:CHU_RS18320
uniprot id: A0A6N4SWX5
names: Subcellular Location Annotation
messages: Membrane

269798:CHU RS09115
gene id: 269798:CHU_RS09115
uniprot id: A0A6N4SS31
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

269798:CHU RS16125
gene id: 269798:CHU_RS16125
uniprot id: A0A6N4SVZ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

269798:CHU RS13760
gene id: 269798:CHU_RS13760
uniprot id: Q11R87
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

269798:CHU RS15410
gene id: 269798:CHU_RS15410
uniprot id: Q11QA5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

269798:CHU RS09860
gene id: 269798:CHU_RS09860
uniprot id: A0A6N4SSD2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

269798:CHU RS04195
gene id: 269798:CHU_RS04195
uniprot id: A0A6N4SPD0
names: Subcellular Location Annotation
messages: Membrane

269798:CHU RS09855
gene id: 269798:CHU_RS09855
uniprot id: A0A6N4SSB1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane
messages: Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins.

269798:CHU RS17655
gene id: 269798:CHU_RS17655
uniprot id: A0A6N4SWQ6
names: Similarity
messages: Belongs to the arginase family.

269798:CHU RS00305
gene id: 269798:CHU_RS00305
uniprot id: A0A6N4SM75
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.
messages: Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

269798:CHU RS16060
gene id: 269798:CHU_RS16060
uniprot id: A0A6N4SVP4
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

269798:CHU RS09780
gene id: 269798:CHU_RS09780
uniprot id: A0A6N4SSE0
names: Subcellular Location Annotation
messages: Membrane

269798:CHU RS13045
gene id: 269798:CHU_RS13045
uniprot id: A0A6N4SU06
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.

269798:CHU RS13365
gene id: 269798:CHU_RS13365
uniprot id: Q11RG6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

269798:CHU RS09700
gene id: 269798:CHU_RS09700
uniprot id: A0A6N4SS87
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.
messages: Cell inner membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system and for the release of the potassium ions to the cytoplasm.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

269798:CHU RS13325
gene id: 269798:CHU_RS13325
uniprot id: A0A6N4SUC5
names: Subcellular Location Annotation
messages: Membrane

269798:CHU RS14940
gene id: 269798:CHU_RS14940
uniprot id: Q11QK1
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

269798:CHU RS01055
gene id: 269798:CHU_RS01055
uniprot id: A0A6N4SMK2
names: Function
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

269798:CHU RS01645
gene id: 269798:CHU_RS01645
uniprot id: A0A6N4SMW9
names: Similarity
messages: Belongs to the histone deacetylase family.

269798:CHU RS10440
gene id: 269798:CHU_RS10440
uniprot id: Q11T61
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the epimerization of D-Ala-D-Ala to D-Ala-L-Ala. Has broad substrate specificity and catalyzes the epimerization of a variety of dipeptides containing an N-terminal Ala followed by a hydrophobic or polar residue, such as Val, Ser and Met (in vitro).
messages: Part of a large, functionally divergent protein family. Protein modeling and substrate docking were used to predict the substrate specificity, prior to biochemical analysis.

269798:CHU RS15235
gene id: 269798:CHU_RS15235
uniprot id: A0A6N4SV09
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

269798:CHU RS06190
gene id: 269798:CHU_RS06190
uniprot id: A0A6N4SQB6
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

269798:CHU RS12735
gene id: 269798:CHU_RS12735
uniprot id: A0A6N4SU79
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

269798:CHU RS16430
gene id: 269798:CHU_RS16430
uniprot id: Q11PP7
names: Function
names: Similarity
messages: Belongs to the aromatic-ring hydroxylase family. KMO subfamily.
messages: Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid.

269798:CHU RS06570
gene id: 269798:CHU_RS06570
uniprot id: A0A6N4SQI2
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

269798:CHU RS10805
gene id: 269798:CHU_RS10805
uniprot id: A0A6N4SSU2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

269798:CHU RS00435
gene id: 269798:CHU_RS00435
uniprot id: Q11YY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

269798:CHU RS01525
gene id: 269798:CHU_RS01525
uniprot id: A0A6N4SMU1
names: Similarity
messages: Belongs to the SIS family. GutQ/KpsF subfamily.

269798:CHU RS16345
gene id: 269798:CHU_RS16345
uniprot id: A0A6N4SWC5
names: Function
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

269798:CHU RS00360
gene id: 269798:CHU_RS00360
uniprot id: A0A6N4SM85
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

269798:CHU RS05610
gene id: 269798:CHU_RS05610
uniprot id: A0A6N4SQ47
names: Similarity
messages: Belongs to the UPF0758 family.

269798:CHU RS06760
gene id: 269798:CHU_RS06760
uniprot id: A0A6N4SQV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

269798:CHU RS17895
gene id: 269798:CHU_RS17895
uniprot id: A0A6N4SWP3
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

269798:CHU RS13255
gene id: 269798:CHU_RS13255
uniprot id: A0A6N4SU43
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Cell inner membrane
messages: Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.

269798:CHU RS07365
gene id: 269798:CHU_RS07365
uniprot id: A0A6N4SQX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

269798:CHU RS15535
gene id: 269798:CHU_RS15535
uniprot id: Q11Q84
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

269798:CHU RS01865
gene id: 269798:CHU_RS01865
uniprot id: A0A6N4SN19
names: Subcellular Location Annotation
messages: Membrane

269798:CHU RS01305
gene id: 269798:CHU_RS01305
uniprot id: A0A6N4SMP8
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

269798:CHU RS03730
gene id: 269798:CHU_RS03730
uniprot id: A0A6N4SP75
names: Subcellular Location Annotation
messages: Cytoplasm

269798:CHU RS14920
gene id: 269798:CHU_RS14920
uniprot id: A0A6N4SUV5
names: Similarity
messages: Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.

269798:CHU RS15865
gene id: 269798:CHU_RS15865
uniprot id: A0A6N4SVK6
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

269798:CHU RS15180
gene id: 269798:CHU_RS15180
uniprot id: A0A6N4SVB5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

269798:CHU RS18545
gene id: 269798:CHU_RS18545
uniprot id: A0A6N4SY12
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

269798:CHU RS07460
gene id: 269798:CHU_RS07460
uniprot id: A0A6N4SR95
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

269798:CHU RS18250
gene id: 269798:CHU_RS18250
uniprot id: A0A6N4SX34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

269798:CHU RS12605
gene id: 269798:CHU_RS12605
uniprot id: A0A6N4STR5
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

269798:CHU RS10260
gene id: 269798:CHU_RS10260
uniprot id: A0A6N4ST27
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

269798:CHU RS09755
gene id: 269798:CHU_RS09755
uniprot id: A0A6N4SSH8
names: Similarity
messages: Belongs to the AlaDH/PNT family.

269798:CHU RS08570
gene id: 269798:CHU_RS08570
uniprot id: A0A6N4SRQ2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 2 lipoyl cofactors covalently.
messages: Forms a 24-polypeptide structural core with octahedral symmetry.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

269798:CHU RS01250
gene id: 269798:CHU_RS01250
uniprot id: A0A6N4SMN7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

269798:CHU RS09595
gene id: 269798:CHU_RS09595
uniprot id: Q11TN7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell inner membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.

269798:CHU RS12580
gene id: 269798:CHU_RS12580
uniprot id: A0A6N4STT0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

269798:CHU RS12225
gene id: 269798:CHU_RS12225
uniprot id: A0A6N4STK3
names: Similarity
messages: Belongs to the IMPACT family.

269798:CHU RS17945
gene id: 269798:CHU_RS17945
uniprot id: A0A6N4SWQ3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

269798:CHU RS07770
gene id: 269798:CHU_RS07770
uniprot id: A0A6N4SRE2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

269798:CHU RS10400
gene id: 269798:CHU_RS10400
uniprot id: A0A6N4SSX5
names: Subcellular Location Annotation
messages: Membrane

269798:CHU RS18995
gene id: 269798:CHU_RS18995
uniprot id: A0A6N4SUV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tonsoku family.
messages: Chromosome

269798:CHU RS17580
gene id: 269798:CHU_RS17580
uniprot id: A0A6N4SWJ3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

269798:CHU RS00565
gene id: 269798:CHU_RS00565
uniprot id: Q11YW2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
messages: Cytoplasm
messages: Homodimer.

269798:CHU RS05190
gene id: 269798:CHU_RS05190
uniprot id: A0A6N4SPX3
names: Subcellular Location Annotation
messages: Membrane

269798:CHU RS13015
gene id: 269798:CHU_RS13015
uniprot id: Q11RN9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

269798:CHU RS04745
gene id: 269798:CHU_RS04745
uniprot id: A0A6N4SPJ0
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.

269798:CHU RS03375
gene id: 269798:CHU_RS03375
uniprot id: A0A6N4SNT9
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

269798:CHU RS07905
gene id: 269798:CHU_RS07905
uniprot id: Q11UM2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

269798:CHU RS06815
gene id: 269798:CHU_RS06815
uniprot id: A0A6N4SQW6
names: Similarity
messages: Belongs to the pyruvate kinase family.

269798:CHU RS00135
gene id: 269798:CHU_RS00135
uniprot id: A0A6N4SM44
names: Similarity
messages: Belongs to the transglycosylase Slt family.

269798:CHU RS01380
gene id: 269798:CHU_RS01380
uniprot id: A0A6N4SMQ5
names: Subcellular Location Annotation
messages: Membrane

269798:CHU RS07265
gene id: 269798:CHU_RS07265
uniprot id: A0A6N4SQV7
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.

269798:CHU RS13840
gene id: 269798:CHU_RS13840
uniprot id: Q11R71
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
messages: Belongs to the KdsB family.
messages: Cytoplasm

269798:CHU RS10140
gene id: 269798:CHU_RS10140
uniprot id: A0A6N4SSJ9
names: Similarity
messages: Belongs to the Dps family.

269798:CHU RS16025
gene id: 269798:CHU_RS16025
uniprot id: A0A6N4SVX4
names: Similarity
messages: Belongs to the TrpF family.

269798:CHU RS03380
gene id: 269798:CHU_RS03380
uniprot id: Q11X93
names: Similarity
messages: Belongs to the BshC family.

269798:CHU RS06730
gene id: 269798:CHU_RS06730
uniprot id: Q11VB2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

269798:CHU RS06670
gene id: 269798:CHU_RS06670
uniprot id: A0A6N4SQK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

269798:CHU RS17685
gene id: 269798:CHU_RS17685
uniprot id: Q11NY7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

269798:CHU RS05315
gene id: 269798:CHU_RS05315
uniprot id: A0A6N4SPV2
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

269798:CHU RS18910
gene id: 269798:CHU_RS18910
uniprot id: A0A6N4SSX8
names: Function
names: Similarity
messages: Belongs to the RlpA family.
messages: Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.

269798:CHU RS02255
gene id: 269798:CHU_RS02255
uniprot id: A0A6N4SN71
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

269798:CHU RS12460
gene id: 269798:CHU_RS12460
uniprot id: A0A6N4STN4
names: Similarity
messages: Belongs to the ParB family.

269798:CHU RS01520
gene id: 269798:CHU_RS01520
uniprot id: A0A6N4SMU2
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

269798:CHU RS15145
gene id: 269798:CHU_RS15145
uniprot id: A0A6N4SV54
names: Subcellular Location Annotation
messages: Membrane

269798:CHU RS16195
gene id: 269798:CHU_RS16195
uniprot id: Q11PU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0060 family.
messages: Cell inner membrane

269798:CHU RS04125
gene id: 269798:CHU_RS04125
uniprot id: A0A6N4SPC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

269798:CHU RS02260
gene id: 269798:CHU_RS02260
uniprot id: Q11XX4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

269798:CHU RS17720
gene id: 269798:CHU_RS17720
uniprot id: A0A6N4SWG0
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

269798:CHU RS17675
gene id: 269798:CHU_RS17675
uniprot id: A0A6N4SX04
names: Similarity
messages: Belongs to the DODA-type extradiol aromatic ring-opening dioxygenase family.

269798:CHU RS12775
gene id: 269798:CHU_RS12775
uniprot id: Q11RT6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

269798:CHU RS15240
gene id: 269798:CHU_RS15240
uniprot id: Q11QD9
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

269798:CHU RS13395
gene id: 269798:CHU_RS13395
uniprot id: A0A6N4SU65
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

269798:CHU RS15325
gene id: 269798:CHU_RS15325
uniprot id: Q11QC2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

269798:CHU RS18180
gene id: 269798:CHU_RS18180
uniprot id: A0A6N4SWN5
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

269798:CHU RS17485
gene id: 269798:CHU_RS17485
uniprot id: A0A6N4SW58
names: Similarity
messages: Belongs to the type IA topoisomerase family.

269798:CHU RS16570
gene id: 269798:CHU_RS16570
uniprot id: Q11PL9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.

269798:CHU RS16090
gene id: 269798:CHU_RS16090
uniprot id: A0A6N4SW41
names: Similarity
messages: Belongs to the MreC family.

269798:CHU RS00365
gene id: 269798:CHU_RS00365
uniprot id: A0A6N4SM86
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

269798:CHU RS06010
gene id: 269798:CHU_RS06010
uniprot id: A0A6N4SQF8
names: Similarity
messages: In the N-terminal section; belongs to the phytochrome family.

269798:CHU RS15415
gene id: 269798:CHU_RS15415
uniprot id: Q11QA4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

269798:CHU RS06280
gene id: 269798:CHU_RS06280
uniprot id: A0A6N4SQF2
names: Subcellular Location Annotation
messages: Membrane

269798:CHU RS16000
gene id: 269798:CHU_RS16000
uniprot id: A0A6N4SVG8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

269798:CHU RS03145
gene id: 269798:CHU_RS03145
uniprot id: A0A6N4SNR3
names: Function
names: Similarity
messages: Belongs to the APS kinase family.
messages: Catalyzes the synthesis of activated sulfate.

269798:CHU RS15280
gene id: 269798:CHU_RS15280
uniprot id: Q11QD1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

269798:CHU RS17010
gene id: 269798:CHU_RS17010
uniprot id: Q11PC9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

269798:CHU RS13320
gene id: 269798:CHU_RS13320
uniprot id: Q11RH5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell inner membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).

269798:CHU RS01025
gene id: 269798:CHU_RS01025
uniprot id: A0A6N4SMJ4
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

269798:CHU RS09100
gene id: 269798:CHU_RS09100
uniprot id: Q11TY6
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Feedback inhibited by histidine.

269798:CHU RS00380
gene id: 269798:CHU_RS00380
uniprot id: A0A6N4SM82
names: Similarity
messages: Belongs to the threonine synthase family.

269798:CHU RS11755
gene id: 269798:CHU_RS11755
uniprot id: A0A6N4STA8
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

269798:CHU RS18375
gene id: 269798:CHU_RS18375
uniprot id: A0A6N4SWN0
names: Similarity
messages: Belongs to the AHA1 family.

269798:CHU RS06065
gene id: 269798:CHU_RS06065
uniprot id: A0A6N4SQE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

269798:CHU RS18555
gene id: 269798:CHU_RS18555
uniprot id: Q11NG0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.
messages: Cell inner membrane
messages: Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

269798:CHU RS13735
gene id: 269798:CHU_RS13735
uniprot id: A0A6N4SUL0
names: Similarity
messages: Belongs to the ComB family.

269798:CHU RS08095
gene id: 269798:CHU_RS08095
uniprot id: Q11UI4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell inner membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.

269798:CHU RS07040
gene id: 269798:CHU_RS07040
uniprot id: Q11V49
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

269798:CHU RS16545
gene id: 269798:CHU_RS16545
uniprot id: Q11PM4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.

269798:CHU RS14260
gene id: 269798:CHU_RS14260
uniprot id: A0A6N4SUU7
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

269798:CHU RS04455
gene id: 269798:CHU_RS04455
uniprot id: A0A6N4SPH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

269798:CHU RS10880
gene id: 269798:CHU_RS10880
uniprot id: A0A6N4ST53
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

269798:CHU RS13910
gene id: 269798:CHU_RS13910
uniprot id: A0A6N4SUV3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

269798:CHU RS02460
gene id: 269798:CHU_RS02460
uniprot id: A0A6N4SNC8
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

269798:CHU RS15105
gene id: 269798:CHU_RS15105
uniprot id: A0A6N4SVD1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

269798:CHU RS17640
gene id: 269798:CHU_RS17640
uniprot id: Q11NZ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.

269798:CHU RS05655
gene id: 269798:CHU_RS05655
uniprot id: A0A6N4SQ18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polysaccharide lyase 1 family.
messages: Secreted

269798:CHU RS16385
gene id: 269798:CHU_RS16385
uniprot id: A0A6N4SVL8
names: Subcellular Location Annotation
messages: Membrane

269798:CHU RS06805
gene id: 269798:CHU_RS06805
uniprot id: Q11V97
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

269798:CHU RS08740
gene id: 269798:CHU_RS08740
uniprot id: A0A6N4SRR8
names: Subcellular Location Annotation
messages: Membrane

269798:CHU RS10900
gene id: 269798:CHU_RS10900
uniprot id: Q11SW8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3.A.1.125) family.
messages: Cell inner membrane
messages: Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.
messages: The complex is composed of two ATP-binding proteins (LolD) and two transmembrane proteins (LolC and LolE).

269798:CHU RS18670
gene id: 269798:CHU_RS18670
uniprot id: A0A6N4SXV5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

269798:CHU RS10285
gene id: 269798:CHU_RS10285
uniprot id: A0A6N4SSP3
names: Subcellular Location Annotation
messages: Membrane

269798:CHU RS14455
gene id: 269798:CHU_RS14455
uniprot id: Q11QU6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.

269798:CHU RS01900
gene id: 269798:CHU_RS01900
uniprot id: A0A6N4SN02
names: Subcellular Location Annotation
messages: Membrane

269798:CHU RS16825
gene id: 269798:CHU_RS16825
uniprot id: A0A6N4SVV1
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

269798:CHU RS02710
gene id: 269798:CHU_RS02710
uniprot id: A0A6N4SNG7
names: Similarity
messages: Belongs to the SusD family.

269798:CHU RS10520
gene id: 269798:CHU_RS10520
uniprot id: A0A6N4SSJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

269798:CHU RS09960
gene id: 269798:CHU_RS09960
uniprot id: A0A6N4SSH7
names: Similarity
messages: Belongs to the sterol desaturase family.

269798:CHU RS02535
gene id: 269798:CHU_RS02535
uniprot id: Q11XR8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

269798:CHU RS05240
gene id: 269798:CHU_RS05240
uniprot id: A0A6N4SPU3
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

269798:CHU RS01595
gene id: 269798:CHU_RS01595
uniprot id: A0A6N4SMV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

269798:CHU RS00145
gene id: 269798:CHU_RS00145
uniprot id: Q11Z44
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

269798:CHU RS13805
gene id: 269798:CHU_RS13805
uniprot id: A0A6N4SV06
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic Ku family.
messages: Homodimer. Interacts with LigD.
messages: With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD.

269798:CHU RS03205
gene id: 269798:CHU_RS03205
uniprot id: Q11XD0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

269798:CHU RS15425
gene id: 269798:CHU_RS15425
uniprot id: Q11QA2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

269798:CHU RS11870
gene id: 269798:CHU_RS11870
uniprot id: A0A6N4STQ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

269798:CHU RS01015
gene id: 269798:CHU_RS01015
uniprot id: A0A6N4SMI7
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

269798:CHU RS11790
gene id: 269798:CHU_RS11790
uniprot id: A0A6N4STH9
names: Similarity
messages: Belongs to the NAPRTase family.

269798:CHU RS07325
gene id: 269798:CHU_RS07325
uniprot id: A0A6N4SQX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

269798:CHU RS12240
gene id: 269798:CHU_RS12240
uniprot id: A0A6N4STI7
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

269798:CHU RS02670
gene id: 269798:CHU_RS02670
uniprot id: A0A6N4SNH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

269798:CHU RS04740
gene id: 269798:CHU_RS04740
uniprot id: A0A6N4SPQ6
names: Similarity
messages: Belongs to the SufE family.

269798:CHU RS07775
gene id: 269798:CHU_RS07775
uniprot id: A0A6N4SR79
names: Similarity
messages: Belongs to the DEAD box helicase family.

269798:CHU RS00490
gene id: 269798:CHU_RS00490
uniprot id: A0A6N4SMB3
names: Similarity
messages: Belongs to the peptidase S41A family.

269798:CHU RS00270
gene id: 269798:CHU_RS00270
uniprot id: A0A6N4SM69
names: Similarity
names: Subunit
messages: Belongs to the aldehyde dehydrogenase family.
messages: Homotetramer.

269798:CHU RS14045
gene id: 269798:CHU_RS14045
uniprot id: A0A6N4SUY8
names: Subcellular Location Annotation
messages: Membrane

269798:CHU RS06210
gene id: 269798:CHU_RS06210
uniprot id: A0A6N4SQJ7
names: Similarity
messages: Belongs to the citrate synthase family.

269798:CHU RS00955
gene id: 269798:CHU_RS00955
uniprot id: Q11YP2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase delta chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

269798:CHU RS03325
gene id: 269798:CHU_RS03325
uniprot id: A0A6N4SNX5
names: Similarity
messages: Belongs to the IPP isomerase type 1 family.

269798:CHU RS13250
gene id: 269798:CHU_RS13250
uniprot id: A0A6N4SU96
names: Subcellular Location Annotation
messages: Membrane

269798:CHU RS15110
gene id: 269798:CHU_RS15110
uniprot id: A0A6N4SVI6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

269798:CHU RS16105
gene id: 269798:CHU_RS16105
uniprot id: A0A6N4SVI7
names: Caution
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

269798:CHU RS15820
gene id: 269798:CHU_RS15820
uniprot id: Q11Q26
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

269798:CHU RS02740
gene id: 269798:CHU_RS02740
uniprot id: A0A6N4SNI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

269798:CHU RS00880
gene id: 269798:CHU_RS00880
uniprot id: A0A6N4SMH2
names: Subcellular Location Annotation
messages: Membrane

269798:CHU RS15260
gene id: 269798:CHU_RS15260
uniprot id: Q11QD5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

269798:CHU RS08225
gene id: 269798:CHU_RS08225
uniprot id: A0A6N4SRL9
names: Subcellular Location Annotation
messages: Membrane

269798:CHU RS04850
gene id: 269798:CHU_RS04850
uniprot id: A0A6N4SPP6
names: Function
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

269798:CHU RS12035
gene id: 269798:CHU_RS12035
uniprot id: A0A6N4STN6
names: Similarity
messages: Belongs to the YciI family.

269798:CHU RS01885
gene id: 269798:CHU_RS01885
uniprot id: A0A6N4SMZ9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueG family.
messages: Binds 2 [4Fe-4S] clusters per monomer.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

269798:CHU RS15795
gene id: 269798:CHU_RS15795
uniprot id: A0A6N4SVT4
names: Similarity
messages: Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.

269798:CHU RS15860
gene id: 269798:CHU_RS15860
uniprot id: A0A6N4SVD9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell inner membrane
messages: Membrane

269798:CHU RS16115
gene id: 269798:CHU_RS16115
uniprot id: A0A6N4SVL1
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Homotetramer.

269798:CHU RS17900
gene id: 269798:CHU_RS17900
uniprot id: A0A6N4SWE1
names: Cofactor
names: Function
names: Similarity
messages: Adenine glycosylase active on G-A mispairs.
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.

269798:CHU RS15985
gene id: 269798:CHU_RS15985
uniprot id: A0A6N4SW57
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I fumarase family.
messages: Catalyzes the reversible hydration of fumarate to (S)-malate.
messages: Homodimer.

269798:CHU RS14080
gene id: 269798:CHU_RS14080
uniprot id: Q11R22
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FBPase class 1 family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.

269798:CHU RS09095
gene id: 269798:CHU_RS09095
uniprot id: A0A6N4SRV0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

269798:CHU RS05885
gene id: 269798:CHU_RS05885
uniprot id: A0A6N4SQ81
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

269798:CHU RS14515
gene id: 269798:CHU_RS14515
uniprot id: A0A6N4SUS6
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

269798:CHU RS10360
gene id: 269798:CHU_RS10360
uniprot id: A0A6N4ST48
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

269798:CHU RS00870
gene id: 269798:CHU_RS00870
uniprot id: A0A6N4SMG6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

269798:CHU RS13990
gene id: 269798:CHU_RS13990
uniprot id: A0A6N4SUR1
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

269798:CHU RS15340
gene id: 269798:CHU_RS15340
uniprot id: Q11QB9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

269798:CHU RS12975
gene id: 269798:CHU_RS12975
uniprot id: A0A6N4SUB5
names: Similarity
messages: Belongs to the Nudix hydrolase family.

269798:CHU RS02545
gene id: 269798:CHU_RS02545
uniprot id: Q11XR6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

269798:CHU RS01610
gene id: 269798:CHU_RS01610
uniprot id: A0A6N4SMX8
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

269798:CHU RS15895
gene id: 269798:CHU_RS15895
uniprot id: A0A6N4SVM5
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

269798:CHU RS15375
gene id: 269798:CHU_RS15375
uniprot id: Q11QB2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

269798:CHU RS14540
gene id: 269798:CHU_RS14540
uniprot id: Q11QT1
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

269798:CHU RS09565
gene id: 269798:CHU_RS09565
uniprot id: Q11TP3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

269798:CHU RS07275
gene id: 269798:CHU_RS07275
uniprot id: A0A6N4SQX0
names: Similarity
messages: Belongs to the UPF0758 family.

269798:CHU RS08475
gene id: 269798:CHU_RS08475
uniprot id: A0A6N4SRM8
names: Similarity
messages: Belongs to the glutamine synthetase family.

269798:CHU RS04375
gene id: 269798:CHU_RS04375
uniprot id: A0A6N4SPG6
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

269798:CHU RS09005
gene id: 269798:CHU_RS09005
uniprot id: A0A6N4SS09
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

269798:CHU RS17795
gene id: 269798:CHU_RS17795
uniprot id: A0A6N4SWM4
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

269798:CHU RS07850
gene id: 269798:CHU_RS07850
uniprot id: A0A6N4SRB8
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

269798:CHU RS15245
gene id: 269798:CHU_RS15245
uniprot id: Q11QD8
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

269798:CHU RS16075
gene id: 269798:CHU_RS16075
uniprot id: A0A6N4SVY7
names: Subcellular Location Annotation
messages: Membrane

269798:CHU RS11695
gene id: 269798:CHU_RS11695
uniprot id: A0A6N4STF9
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

269798:CHU RS05065
gene id: 269798:CHU_RS05065
uniprot id: Q11WA1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

269798:CHU RS13570
gene id: 269798:CHU_RS13570
uniprot id: A0A6N4SUP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase Slt family.
messages: Cell outer membrane
messages: Membrane

269798:CHU RS00070
gene id: 269798:CHU_RS00070
uniprot id: A0A6N4SM38
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

269798:CHU RS06610
gene id: 269798:CHU_RS06610
uniprot id: A0A6N4SQN7
names: Similarity
messages: Belongs to the band 7/mec-2 family.

269798:CHU RS15645
gene id: 269798:CHU_RS15645
uniprot id: A0A6N4SV50
names: Similarity
messages: Belongs to the Skp family.

269798:CHU RS10990
gene id: 269798:CHU_RS10990
uniprot id: Q11SV1
names: Function
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

269798:CHU RS08305
gene id: 269798:CHU_RS08305
uniprot id: A0A6N4SRK1
names: Subcellular Location Annotation
messages: Membrane

269798:CHU RS16435
gene id: 269798:CHU_RS16435
uniprot id: A0A6N4SW48
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the kynureninase family.
messages: Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

269798:CHU RS10790
gene id: 269798:CHU_RS10790
uniprot id: A0A6N4SSW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

269798:CHU RS01695
gene id: 269798:CHU_RS01695
uniprot id: Q11Y93
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

269798:CHU RS02540
gene id: 269798:CHU_RS02540
uniprot id: A0A6N4SND8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 30 kDa subunit family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

269798:CHU RS16530
gene id: 269798:CHU_RS16530
uniprot id: Q11PM7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

269798:CHU RS16425
gene id: 269798:CHU_RS16425
uniprot id: A0A6N4SW00
names: Similarity
messages: Belongs to the LOG family.

269798:CHU RS02830
gene id: 269798:CHU_RS02830
uniprot id: A0A6N4SNM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YejK family.
messages: nucleoid

269798:CHU RS00300
gene id: 269798:CHU_RS00300
uniprot id: A0A6N4SM78
names: Similarity
messages: Belongs to the asparagine synthetase family.

269798:CHU RS00595
gene id: 269798:CHU_RS00595
uniprot id: Q11YV6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

269798:CHU RS15000
gene id: 269798:CHU_RS15000
uniprot id: A0A6N4SVA0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. SOTCase family.
messages: Catalyzes the transfer of the carbamoyl group from carbamoyl phosphate to the delta-amino group of N(2)-succinyl-L-ornithine to produce N(2)-succinyl-L-citrulline. Is essential for arginine biosynthesis.
messages: Homotrimer.

269798:CHU RS01710
gene id: 269798:CHU_RS01710
uniprot id: Q11Y90
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

269798:CHU RS04835
gene id: 269798:CHU_RS04835
uniprot id: A0A6N4SPQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0187 family.
messages: Membrane

269798:CHU RS06625
gene id: 269798:CHU_RS06625
uniprot id: A0A6N4SQM9
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

269798:CHU RS10080
gene id: 269798:CHU_RS10080
uniprot id: A0A6N4SSY9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

269798:CHU RS12955
gene id: 269798:CHU_RS12955
uniprot id: A0A6N4SUC4
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

269798:CHU RS16930
gene id: 269798:CHU_RS16930
uniprot id: A0A6N4SWN3
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.

269798:CHU RS17080
gene id: 269798:CHU_RS17080
uniprot id: Q11PB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

269798:CHU RS00555
gene id: 269798:CHU_RS00555
uniprot id: A0A6N4SMC0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

269798:CHU RS00950
gene id: 269798:CHU_RS00950
uniprot id: Q11YP3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell inner membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.

269798:CHU RS17015
gene id: 269798:CHU_RS17015
uniprot id: Q11PC8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

269798:CHU RS02300
gene id: 269798:CHU_RS02300
uniprot id: A0A6N4SN87
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

269798:CHU RS00440
gene id: 269798:CHU_RS00440
uniprot id: Q11YY5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

269798:CHU RS03305
gene id: 269798:CHU_RS03305
uniprot id: Q11XA9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. METTL16/RlmF family.
messages: Cytoplasm
messages: Specifically methylates the adenine in position 1618 of 23S rRNA.

269798:CHU RS04410
gene id: 269798:CHU_RS04410
uniprot id: A0A6N4SPD2
names: Subcellular Location Annotation
messages: Membrane

269798:CHU RS16130
gene id: 269798:CHU_RS16130
uniprot id: A0A6N4SW87
names: Similarity
messages: Belongs to the XseB family.

269798:CHU RS13260
gene id: 269798:CHU_RS13260
uniprot id: Q11RI7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

269798:CHU RS06725
gene id: 269798:CHU_RS06725
uniprot id: Q11VB3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

269798:CHU RS02925
gene id: 269798:CHU_RS02925
uniprot id: A0A6N4SNM8
names: Similarity
messages: Belongs to the IucA/IucC family.

269798:CHU RS07795
gene id: 269798:CHU_RS07795
uniprot id: Q11UP4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm

269798:CHU RS14950
gene id: 269798:CHU_RS14950
uniprot id: A0A6N4SV92
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.

269798:CHU RS15435
gene id: 269798:CHU_RS15435
uniprot id: A0A6N4SV59
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

269798:CHU RS11995
gene id: 269798:CHU_RS11995
uniprot id: A0A6N4STM3
names: Similarity
messages: Belongs to the peptidase S49 family.

269798:CHU RS03660
gene id: 269798:CHU_RS03660
uniprot id: A0A6N4SNZ5
names: Function
names: Similarity
messages: Belongs to the PemK/MazF family.
messages: Toxic component of a type II toxin-antitoxin (TA) system.

269798:CHU RS16990
gene id: 269798:CHU_RS16990
uniprot id: A0A6N4SVV3
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

269798:CHU RS14150
gene id: 269798:CHU_RS14150
uniprot id: A0A6N4SV07
names: Subcellular Location Annotation
messages: Membrane

269798:CHU RS15735
gene id: 269798:CHU_RS15735
uniprot id: A0A6N4SVA7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the flotillin-like FloA family.
messages: Cell membrane
messages: Found in functional membrane microdomains (FMM) that may be equivalent to eukaryotic membrane rafts FMMs are highly dynamic and increase in number as cells age. Flotillins are thought to be important factors in membrane fluidity.
messages: Homooligomerizes.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane raft

269798:CHU RS12470
gene id: 269798:CHU_RS12470
uniprot id: A0A6N4STR0
names: Similarity
messages: Belongs to the DapB family.

269798:CHU RS10985
gene id: 269798:CHU_RS10985
uniprot id: A0A6N4STG2
names: Similarity
messages: Belongs to the TPP enzyme family.

269798:CHU RS17755
gene id: 269798:CHU_RS17755
uniprot id: A0A6N4SWF6
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.

269798:CHU RS12505
gene id: 269798:CHU_RS12505
uniprot id: A0A6N4STW5
names: Similarity
messages: Belongs to the DEAD box helicase family.

269798:CHU RS17545
gene id: 269798:CHU_RS17545
uniprot id: A0A6N4SWB9
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

269798:CHU RS01265
gene id: 269798:CHU_RS01265
uniprot id: Q11YI1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

269798:CHU RS16950
gene id: 269798:CHU_RS16950
uniprot id: A0A6N4SVX0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of glycine to tRNA(Gly).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

269798:CHU RS10085
gene id: 269798:CHU_RS10085
uniprot id: A0A6N4SSM4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

269798:CHU RS08010
gene id: 269798:CHU_RS08010
uniprot id: Q11UK0
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

269798:CHU RS17140
gene id: 269798:CHU_RS17140
uniprot id: A0A6N4SWS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

269798:CHU RS07560
gene id: 269798:CHU_RS07560
uniprot id: A0A6N4SR16
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

269798:CHU RS02705
gene id: 269798:CHU_RS02705
uniprot id: A0A6N4SNK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

269798:CHU RS14620
gene id: 269798:CHU_RS14620
uniprot id: A0A6N4SV94
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

269798:CHU RS00945
gene id: 269798:CHU_RS00945
uniprot id: A0A6N4SMH8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase C chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

269798:CHU RS00125
gene id: 269798:CHU_RS00125
uniprot id: A0A6N4SM46
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell inner membrane
messages: Forms a complex with TatC.
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.

269798:CHU RS15450
gene id: 269798:CHU_RS15450
uniprot id: Q11Q98
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

269798:CHU RS07640
gene id: 269798:CHU_RS07640
uniprot id: A0A6N4SRC6
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

269798:CHU RS16620
gene id: 269798:CHU_RS16620
uniprot id: Q11PK9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

269798:CHU RS06665
gene id: 269798:CHU_RS06665
uniprot id: Q11VC5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

269798:CHU RS12345
gene id: 269798:CHU_RS12345
uniprot id: Q11S24
names: Activity Regulation
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.

269798:CHU RS16150
gene id: 269798:CHU_RS16150
uniprot id: Q11PV4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 independent methionine synthase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.

269798:CHU RS11990
gene id: 269798:CHU_RS11990
uniprot id: Q11S94
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

269798:CHU RS17185
gene id: 269798:CHU_RS17185
uniprot id: A0A6N4SW52
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the peroxiredoxin family. Tpx subfamily.
messages: Homodimer.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. In this atypical 2-Cys peroxiredoxin, C(R) is present in the same subunit to form an intramolecular disulfide. The disulfide is subsequently reduced by thioredoxin.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

269798:CHU RS10540
gene id: 269798:CHU_RS10540
uniprot id: A0A6N4SSS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Membrane

269798:CHU RS15925
gene id: 269798:CHU_RS15925
uniprot id: Q11Q02
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

269798:CHU RS02855
gene id: 269798:CHU_RS02855
uniprot id: A0A6N4SNN8
names: Similarity
messages: Belongs to the peptidase M1 family.

269798:CHU RS14635
gene id: 269798:CHU_RS14635
uniprot id: A0A6N4SV96
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

269798:CHU RS04755
gene id: 269798:CHU_RS04755
uniprot id: A0A6N4SPR9
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

269798:CHU RS17990
gene id: 269798:CHU_RS17990
uniprot id: A0A6N4SWD4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

269798:CHU RS04555
gene id: 269798:CHU_RS04555
uniprot id: A0A6N4SPK0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

269798:CHU RS15275
gene id: 269798:CHU_RS15275
uniprot id: A0A6N4SV51
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell inner membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

269798:CHU RS03535
gene id: 269798:CHU_RS03535
uniprot id: A0A6N4SP14
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

269798:CHU RS10935
gene id: 269798:CHU_RS10935
uniprot id: A0A6N4ST63
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

269798:CHU RS05100
gene id: 269798:CHU_RS05100
uniprot id: Q11W94
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

269798:CHU RS09425
gene id: 269798:CHU_RS09425
uniprot id: A0A6N4SS07
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

269798:CHU RS12945
gene id: 269798:CHU_RS12945
uniprot id: A0A6N4STZ9
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

269798:CHU RS02975
gene id: 269798:CHU_RS02975
uniprot id: A0A6N4SNL3
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

269798:CHU RS08340
gene id: 269798:CHU_RS08340
uniprot id: A0A6N4SRR5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

269798:CHU RS10890
gene id: 269798:CHU_RS10890
uniprot id: A0A6N4SSZ1
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

269798:CHU RS16640
gene id: 269798:CHU_RS16640
uniprot id: Q11PK5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

269798:CHU RS01655
gene id: 269798:CHU_RS01655
uniprot id: A0A6N4SMW8
names: Subcellular Location Annotation
messages: Membrane

269798:CHU RS02265
gene id: 269798:CHU_RS02265
uniprot id: Q11XX3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

269798:CHU RS08440
gene id: 269798:CHU_RS08440
uniprot id: A0A6N4SRL4
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

269798:CHU RS12745
gene id: 269798:CHU_RS12745
uniprot id: Q11RU2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

269798:CHU RS10320
gene id: 269798:CHU_RS10320
uniprot id: A0A6N4SSI0
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

269798:CHU RS10340
gene id: 269798:CHU_RS10340
uniprot id: A0A6N4SSK2
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

269798:CHU RS12165
gene id: 269798:CHU_RS12165
uniprot id: A0A6N4STP5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

269798:CHU RS14775
gene id: 269798:CHU_RS14775
uniprot id: A0A6N4SV36
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

269798:CHU RS05540
gene id: 269798:CHU_RS05540
uniprot id: A0A6N4SQ22
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Binds 1 copper ion per subunit, denoted as copper B.
messages: Binds 2 heme groups per subunit, denoted as high- and low-spin.
messages: Membrane

269798:CHU RS10765
gene id: 269798:CHU_RS10765
uniprot id: A0A6N4ST50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Membrane

269798:CHU RS04645
gene id: 269798:CHU_RS04645
uniprot id: A0A6N4SPK6
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

269798:CHU RS16135
gene id: 269798:CHU_RS16135
uniprot id: A0A6N4SW53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XseA family.
messages: Cytoplasm

269798:CHU RS09375
gene id: 269798:CHU_RS09375
uniprot id: A0A6N4SRZ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.
messages: Cell inner membrane
messages: Involved in the import of queuosine (Q) precursors, required for Q precursor salvage.

269798:CHU RS07660
gene id: 269798:CHU_RS07660
uniprot id: A0A6N4SR35
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protoporphyrinogen/coproporphyrinogen oxidase family. Coproporphyrinogen III oxidase subfamily.
messages: Cytoplasm
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the oxidation of coproporphyrinogen III to coproporphyrin III.

269798:CHU RS13025
gene id: 269798:CHU_RS13025
uniprot id: A0A6N4SU10
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

269798:CHU RS18000
gene id: 269798:CHU_RS18000
uniprot id: Q11NS4
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

269798:CHU RS15430
gene id: 269798:CHU_RS15430
uniprot id: Q11QA1
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

269798:CHU RS13300
gene id: 269798:CHU_RS13300
uniprot id: A0A6N4SU29
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

269798:CHU RS12935
gene id: 269798:CHU_RS12935
uniprot id: A0A6N4STY6
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

269798:CHU RS16095
gene id: 269798:CHU_RS16095
uniprot id: A0A6N4SVD8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

269798:CHU RS11680
gene id: 269798:CHU_RS11680
uniprot id: A0A6N4ST92
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

269798:CHU RS13170
gene id: 269798:CHU_RS13170
uniprot id: A0A6N4SU30
names: Similarity
names: Subunit
messages: Belongs to the RNase H family.
messages: Monomer.

269798:CHU RS19350
gene id: 269798:CHU_RS19350
uniprot id: Q11T75
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

269798:CHU RS15365
gene id: 269798:CHU_RS15365
uniprot id: A0A6N4SVG7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

269798:CHU RS15385
gene id: 269798:CHU_RS15385
uniprot id: Q11QB0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

269798:CHU RS15370
gene id: 269798:CHU_RS15370
uniprot id: Q11QB3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

269798:CHU RS00610
gene id: 269798:CHU_RS00610
uniprot id: Q11YV3
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

269798:CHU RS09915
gene id: 269798:CHU_RS09915
uniprot id: A0A6N4SSL1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

269798:CHU RS18060
gene id: 269798:CHU_RS18060
uniprot id: A0A6N4SWG9
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

269798:CHU RS10625
gene id: 269798:CHU_RS10625
uniprot id: A0A6N4SSY6
names: Subcellular Location Annotation
messages: Membrane

269798:CHU RS01080
gene id: 269798:CHU_RS01080
uniprot id: A0A6N4SMK0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the serine/threonine dehydratase family.
messages: Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
messages: Homotetramer.

269798:CHU RS06150
gene id: 269798:CHU_RS06150
uniprot id: Q11VN1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
messages: Cytoplasm
messages: Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
messages: Homodimer. UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

269798:CHU RS08050
gene id: 269798:CHU_RS08050
uniprot id: A0A6N4SRL5
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

269798:CHU RS11615
gene id: 269798:CHU_RS11615
uniprot id: A0A6N4STU5
names: Similarity
messages: Belongs to the peptidase C59 family.

269798:CHU RS04575
gene id: 269798:CHU_RS04575
uniprot id: A0A6N4SPG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

269798:CHU RS15420
gene id: 269798:CHU_RS15420
uniprot id: Q11QA3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

269798:CHU RS16490
gene id: 269798:CHU_RS16490
uniprot id: A0A6N4SW60
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

269798:CHU RS13795
gene id: 269798:CHU_RS13795
uniprot id: A0A6N4SUU2
names: Function
names: Similarity
messages: Belongs to the catalase family. HPII subfamily.
messages: Serves to protect cells from the toxic effects of hydrogen peroxide.

269798:CHU RS07510
gene id: 269798:CHU_RS07510
uniprot id: Q11UV2
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.

269798:CHU RS18620
gene id: 269798:CHU_RS18620
uniprot id: Q11NE7
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

269798:CHU RS15215
gene id: 269798:CHU_RS15215
uniprot id: A0A6N4SV47
names: Similarity
messages: Belongs to the pirin family.

269798:CHU RS10700
gene id: 269798:CHU_RS10700
uniprot id: A0A6N4SSS0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

269798:CHU RS12850
gene id: 269798:CHU_RS12850
uniprot id: A0A6N4SU16
names: Subcellular Location Annotation
messages: Membrane

269798:CHU RS12140
gene id: 269798:CHU_RS12140
uniprot id: A0A6N4STG7
names: Similarity
messages: Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family. Bacterial alpha-2-macroglobulin subfamily.

269798:CHU RS18055
gene id: 269798:CHU_RS18055
uniprot id: Q11NR3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

269798:CHU RS00355
gene id: 269798:CHU_RS00355
uniprot id: Q11Z03
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

269798:CHU RS17810
gene id: 269798:CHU_RS17810
uniprot id: A0A6N4SWU0
names: Similarity
messages: Belongs to the RecJ family.

269798:CHU RS02530
gene id: 269798:CHU_RS02530
uniprot id: A0A6N4SND6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell inner membrane
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

269798:CHU RS09580
gene id: 269798:CHU_RS09580
uniprot id: A0A6N4SS38
names: Similarity
messages: Belongs to the DNA photolyase family.

269798:CHU RS07395
gene id: 269798:CHU_RS07395
uniprot id: A0A6N4SR31
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

269798:CHU RS04130
gene id: 269798:CHU_RS04130
uniprot id: A0A6N4SP83
names: Similarity
messages: Belongs to the ABC transporter superfamily.

269798:CHU RS03405
gene id: 269798:CHU_RS03405
uniprot id: Q11X87
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF nuclease family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

269798:CHU RS00710
gene id: 269798:CHU_RS00710
uniprot id: A0A6N4SME2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

269798:CHU RS02930
gene id: 269798:CHU_RS02930
uniprot id: A0A6N4SNJ5
names: Similarity
messages: Belongs to the lysine N(6)-hydroxylase/L-ornithine N(5)-oxygenase family.

269798:CHU RS06990
gene id: 269798:CHU_RS06990
uniprot id: A0A6N4SQV4
names: Similarity
messages: Belongs to the HMG-CoA lyase family.

269798:CHU RS07715
gene id: 269798:CHU_RS07715
uniprot id: A0A6N4SRD3
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

269798:CHU RS13010
gene id: 269798:CHU_RS13010
uniprot id: A0A6N4SU82
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

269798:CHU RS01260
gene id: 269798:CHU_RS01260
uniprot id: A0A6N4SMP1
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

269798:CHU RS15950
gene id: 269798:CHU_RS15950
uniprot id: Q11PZ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

269798:CHU RS12730
gene id: 269798:CHU_RS12730
uniprot id: A0A6N4STZ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell inner membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

269798:CHU RS15440
gene id: 269798:CHU_RS15440
uniprot id: A0A6N4SX69
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell inner membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

269798:CHU RS01575
gene id: 269798:CHU_RS01575
uniprot id: A0A6N4SMV1
names: Function
names: Similarity
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

269798:CHU RS17535
gene id: 269798:CHU_RS17535
uniprot id: A0A6N4SW71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Membrane

269798:CHU RS16925
gene id: 269798:CHU_RS16925
uniprot id: A0A6N4SW06
names: Similarity
messages: Belongs to the phosphohexose mutase family.

269798:CHU RS14440
gene id: 269798:CHU_RS14440
uniprot id: A0A6N4SUZ6
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

269798:CHU RS15250
gene id: 269798:CHU_RS15250
uniprot id: Q11QD7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

269798:CHU RS14855
gene id: 269798:CHU_RS14855
uniprot id: Q11QL8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

269798:CHU RS09535
gene id: 269798:CHU_RS09535
uniprot id: A0A6N4SSB4
names: Similarity
messages: Belongs to the thioesterase PaaI family.

269798:CHU RS09360
gene id: 269798:CHU_RS09360
uniprot id: Q11TT6
names: Similarity
messages: Belongs to the SAICAR synthetase family.

269798:CHU RS00090
gene id: 269798:CHU_RS00090
uniprot id: A0A6N4SM40
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

269798:CHU RS00425
gene id: 269798:CHU_RS00425
uniprot id: Q11YY8
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

269798:CHU RS11380
gene id: 269798:CHU_RS11380
uniprot id: A0A6N4STF3
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the PRA-PH family.
messages: In the N-terminal section; belongs to the PRA-CH family.

269798:CHU RS08730
gene id: 269798:CHU_RS08730
uniprot id: Q11U60
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

269798:CHU RS15285
gene id: 269798:CHU_RS15285
uniprot id: Q11QD0
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

269798:CHU RS13660
gene id: 269798:CHU_RS13660
uniprot id: A0A6N4SUH4
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

269798:CHU RS09865
gene id: 269798:CHU_RS09865
uniprot id: A0A6N4SSJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

269798:CHU RS16255
gene id: 269798:CHU_RS16255
uniprot id: A0A6N4SVG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

269798:CHU RS15765
gene id: 269798:CHU_RS15765
uniprot id: A0A6N4SVI0
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

269798:CHU RS04060
gene id: 269798:CHU_RS04060
uniprot id: A0A6N4SP91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

269798:CHU RS06145
gene id: 269798:CHU_RS06145
uniprot id: A0A6N4SQH2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UreF family.
messages: Cytoplasm
messages: Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
messages: UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

269798:CHU RS00860
gene id: 269798:CHU_RS00860
uniprot id: A0A6N4SMG2
names: Cofactor
messages: Binds 1 zinc ion per subunit.

269798:CHU RS15060
gene id: 269798:CHU_RS15060
uniprot id: A0A6N4SVH7
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

269798:CHU RS03640
gene id: 269798:CHU_RS03640
uniprot id: A0A6N4SNY1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

269798:CHU RS09995
gene id: 269798:CHU_RS09995
uniprot id: A0A6N4SSK4
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

269798:CHU RS08600
gene id: 269798:CHU_RS08600
uniprot id: A0A6N4SRK5
names: Subcellular Location Annotation
messages: Membrane

269798:CHU RS18075
gene id: 269798:CHU_RS18075
uniprot id: A0A6N4SWL4
names: Similarity
messages: Belongs to the aspartokinase family.

269798:CHU RS12890
gene id: 269798:CHU_RS12890
uniprot id: A0A6N4SU50
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
messages: Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
messages: Homodimer.

269798:CHU RS13210
gene id: 269798:CHU_RS13210
uniprot id: Q11RJ8
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

269798:CHU RS16660
gene id: 269798:CHU_RS16660
uniprot id: Q11PK1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAK/KUP transporter (TC 2.A.72) family.
messages: Cell inner membrane
messages: Transport of potassium into the cell. Likely operates as a K(+):H(+) symporter.

269798:CHU RS00025
gene id: 269798:CHU_RS00025
uniprot id: A0A6N4SM28
names: Similarity
messages: Belongs to the phosphosulfolactate synthase family.

269798:CHU RS14580
gene id: 269798:CHU_RS14580
uniprot id: A0A6N4SVG4
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

269798:CHU RS05085
gene id: 269798:CHU_RS05085
uniprot id: A0A6N4SPV5
names: Subcellular Location Annotation
messages: Membrane

269798:CHU RS08820
gene id: 269798:CHU_RS08820
uniprot id: A0A6N4SS05
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

269798:CHU RS15310
gene id: 269798:CHU_RS15310
uniprot id: Q11QC5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

269798:CHU RS05880
gene id: 269798:CHU_RS05880
uniprot id: Q11VT3
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

269798:CHU RS12245
gene id: 269798:CHU_RS12245
uniprot id: A0A6N4STS5
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

269798:CHU RS04255
gene id: 269798:CHU_RS04255
uniprot id: A0A6N4SPD4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

269798:CHU RS15725
gene id: 269798:CHU_RS15725
uniprot id: Q11Q45
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
messages: Consists of three domains: the N-terminal catalytic domain, the anticodon-binding domain and the C-terminal extension.
messages: Cytoplasm
messages: Homodimer.

269798:CHU RS05140
gene id: 269798:CHU_RS05140
uniprot id: A0A6N4SPW2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the DNA photolyase class-1 family.
messages: Binds 1 5,10-methenyltetrahydrofolate (MTHF) per subunit.
messages: Binds 1 FAD per subunit.
messages: May have a photoreceptor function.

269798:CHU RS13235
gene id: 269798:CHU_RS13235
uniprot id: A0A6N4SU51
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

269798:CHU RS07760
gene id: 269798:CHU_RS07760
uniprot id: A0A6N4SRG0
names: Subcellular Location Annotation
messages: Membrane

269798:CHU RS14770
gene id: 269798:CHU_RS14770
uniprot id: Q11QN5
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

269798:CHU RS06820
gene id: 269798:CHU_RS06820
uniprot id: A0A6N4SQL3
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

269798:CHU RS04890
gene id: 269798:CHU_RS04890
uniprot id: A0A6N4SPT2
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

269798:CHU RS16175
gene id: 269798:CHU_RS16175
uniprot id: A0A6N4SW04
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

269798:CHU RS16610
gene id: 269798:CHU_RS16610
uniprot id: A0A6N4SW79
names: Similarity
messages: Belongs to the peptidase S66 family.

269798:CHU RS05060
gene id: 269798:CHU_RS05060
uniprot id: A0A6N4SPX4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxC family.
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

269798:CHU RS15360
gene id: 269798:CHU_RS15360
uniprot id: Q11QB5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

269798:CHU RS09870
gene id: 269798:CHU_RS09870
uniprot id: A0A6N4SS77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

269798:CHU RS09560
gene id: 269798:CHU_RS09560
uniprot id: A0A6N4SSN2
names: Similarity
messages: Belongs to the peptidase C40 family.

269798:CHU RS06850
gene id: 269798:CHU_RS06850
uniprot id: A0A6N4SQX1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

269798:CHU RS08880
gene id: 269798:CHU_RS08880
uniprot id: A0A6N4SRY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0187 family.
messages: Membrane

269798:CHU RS14420
gene id: 269798:CHU_RS14420
uniprot id: A0A6N4SUY0
names: Similarity
messages: Belongs to the SAM hydrolase / SAM-dependent halogenase family.

269798:CHU RS10745
gene id: 269798:CHU_RS10745
uniprot id: A0A6N4SSY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

269798:CHU RS14675
gene id: 269798:CHU_RS14675
uniprot id: A0A6N4SVA5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

269798:CHU RS00295
gene id: 269798:CHU_RS00295
uniprot id: A0A6N4SM79
names: Similarity
messages: Belongs to the peptidase C40 family.

269798:CHU RS11725
gene id: 269798:CHU_RS11725
uniprot id: A0A6N4STH4
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

269798:CHU RS09370
gene id: 269798:CHU_RS09370
uniprot id: Q11TT4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase Z family.
messages: Binds 2 Zn(2+) ions.
messages: Homodimer.
messages: Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.

269798:CHU RS14460
gene id: 269798:CHU_RS14460
uniprot id: A0A6N4SVE1
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

269798:CHU RS14680
gene id: 269798:CHU_RS14680
uniprot id: Q11QQ3
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 3 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

269798:CHU RS14965
gene id: 269798:CHU_RS14965
uniprot id: A0A6N4SVN1
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

269798:CHU RS11770
gene id: 269798:CHU_RS11770
uniprot id: Q11SD8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell inner membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

269798:CHU RS00575
gene id: 269798:CHU_RS00575
uniprot id: A0A6N4SMB1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

269798:CHU RS19295
gene id: 269798:CHU_RS19295
uniprot id: A0A6N4STQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Membrane

269798:CHU RS13880
gene id: 269798:CHU_RS13880
uniprot id: A0A6N4SUM5
names: Similarity
messages: Belongs to the SUI1 family.

269798:CHU RS07900
gene id: 269798:CHU_RS07900
uniprot id: A0A6N4SRC7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

269798:CHU RS15695
gene id: 269798:CHU_RS15695
uniprot id: A0A6N4SV60
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the adenylate cyclase family. DacA/CdaA subfamily.
messages: Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably a homodimer.

269798:CHU RS17630
gene id: 269798:CHU_RS17630
uniprot id: A0A6N4SW64
names: Similarity
messages: Belongs to the LacAB/RpiB family.

269798:CHU RS19070
gene id: 269798:CHU_RS19070
uniprot id: Q11YX6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

269798:CHU RS15405
gene id: 269798:CHU_RS15405
uniprot id: Q11QA6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

269798:CHU RS14450
gene id: 269798:CHU_RS14450
uniprot id: A0A6N4SUR2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
messages: Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

269798:CHU RS15955
gene id: 269798:CHU_RS15955
uniprot id: A0A6N4SVP1
names: Similarity
messages: Belongs to the CarB family.

269798:CHU RS02690
gene id: 269798:CHU_RS02690
uniprot id: A0A6N4SNG9
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

269798:CHU RS06060
gene id: 269798:CHU_RS06060
uniprot id: A0A6N4SQC0
names: Subcellular Location Annotation
messages: Membrane

269798:CHU RS09445
gene id: 269798:CHU_RS09445
uniprot id: A0A6N4SS93
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

269798:CHU RS17510
gene id: 269798:CHU_RS17510
uniprot id: A0A6N4SWB8
names: Similarity
messages: Belongs to the asparagine synthetase family.

269798:CHU RS06385
gene id: 269798:CHU_RS06385
uniprot id: Q11VI2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

269798:CHU RS12300
gene id: 269798:CHU_RS12300
uniprot id: A0A6N4STK4
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

269798:CHU RS00695
gene id: 269798:CHU_RS00695
uniprot id: A0A6N4SMF0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MetX family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

269798:CHU RS06780
gene id: 269798:CHU_RS06780
uniprot id: A0A6N4SQU3
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

269798:CHU RS15270
gene id: 269798:CHU_RS15270
uniprot id: A0A6N4SVC6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

269798:CHU RS15315
gene id: 269798:CHU_RS15315
uniprot id: A0A6N4SV75
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

269798:CHU RS02450
gene id: 269798:CHU_RS02450
uniprot id: Q11XT5
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

269798:CHU RS06880
gene id: 269798:CHU_RS06880
uniprot id: A0A6N4SQQ5
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

269798:CHU RS03030
gene id: 269798:CHU_RS03030
uniprot id: A0A6N4SNQ4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell inner membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

269798:CHU RS10265
gene id: 269798:CHU_RS10265
uniprot id: A0A6N4SSR5
names: Similarity
messages: Belongs to the AHA1 family.

269798:CHU RS03190
gene id: 269798:CHU_RS03190
uniprot id: A0A6N4SNQ8
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

269798:CHU RS00825
gene id: 269798:CHU_RS00825
uniprot id: A0A6N4SMF6
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

269798:CHU RS15265
gene id: 269798:CHU_RS15265
uniprot id: Q11QD4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

269798:CHU RS11715
gene id: 269798:CHU_RS11715
uniprot id: A0A6N4STL9
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

269798:CHU RS06710
gene id: 269798:CHU_RS06710
uniprot id: A0A6N4SQN0
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

269798:CHU RS09435
gene id: 269798:CHU_RS09435
uniprot id: A0A6N4SS25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

269798:CHU RS18205
gene id: 269798:CHU_RS18205
uniprot id: A0A6N4SX78
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

269798:CHU RS10760
gene id: 269798:CHU_RS10760
uniprot id: A0A6N4SSW2
names: Subcellular Location Annotation
messages: Membrane

269798:CHU RS03015
gene id: 269798:CHU_RS03015
uniprot id: A0A6N4SNR7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

269798:CHU RS04950
gene id: 269798:CHU_RS04950
uniprot id: A0A6N4SPM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

269798:CHU RS08670
gene id: 269798:CHU_RS08670
uniprot id: Q11U72
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
messages: Homodimer.

269798:CHU RS08390
gene id: 269798:CHU_RS08390
uniprot id: Q11UD0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell inner membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

269798:CHU RS18625
gene id: 269798:CHU_RS18625
uniprot id: Q11NE6
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

269798:CHU RS17470
gene id: 269798:CHU_RS17470
uniprot id: A0A6N4SWV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

269798:CHU RS15070
gene id: 269798:CHU_RS15070
uniprot id: A0A6N4SVS5
names: Similarity
messages: Belongs to the Nudix hydrolase family.

269798:CHU RS15320
gene id: 269798:CHU_RS15320
uniprot id: Q11QC3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

269798:CHU RS03735
gene id: 269798:CHU_RS03735
uniprot id: A0A6N4SNZ9
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

269798:CHU RS00550
gene id: 269798:CHU_RS00550
uniprot id: A0A6N4SMB9
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

269798:CHU RS01940
gene id: 269798:CHU_RS01940
uniprot id: A0A6N4SN17
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

269798:CHU RS06835
gene id: 269798:CHU_RS06835
uniprot id: A0A6N4SQV3
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Belongs to the gluconokinase GntK/GntV family.
messages: Homodimer.

269798:CHU RS01470
gene id: 269798:CHU_RS01470
uniprot id: A0A6N4SMV3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

269798:CHU RS10660
gene id: 269798:CHU_RS10660
uniprot id: Q11T17
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RuvC family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.

269798:CHU RS06800
gene id: 269798:CHU_RS06800
uniprot id: A0A6N4SQM1
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

269798:CHU RS01870
gene id: 269798:CHU_RS01870
uniprot id: Q11Y57
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

269798:CHU RS12885
gene id: 269798:CHU_RS12885
uniprot id: A0A6N4STX6
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

269798:CHU RS07475
gene id: 269798:CHU_RS07475
uniprot id: Q11UV9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

269798:CHU RS17855
gene id: 269798:CHU_RS17855
uniprot id: A0A6N4SWQ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell inner membrane
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

269798:CHU RS07785
gene id: 269798:CHU_RS07785
uniprot id: A0A6N4SRB4
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

269798:CHU RS06275
gene id: 269798:CHU_RS06275
uniprot id: Q11VK5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

269798:CHU RS18145
gene id: 269798:CHU_RS18145
uniprot id: A0A6N4SWN8
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

269798:CHU RS13150
gene id: 269798:CHU_RS13150
uniprot id: A0A6N4SU76
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

269798:CHU RS15200
gene id: 269798:CHU_RS15200
uniprot id: A0A6N4SV66
names: Subcellular Location Annotation
messages: Membrane

269798:CHU RS06070
gene id: 269798:CHU_RS06070
uniprot id: A0A6N4SQG7
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

269798:CHU RS02860
gene id: 269798:CHU_RS02860
uniprot id: Q11XK2
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.

269798:CHU RS15330
gene id: 269798:CHU_RS15330
uniprot id: Q11QC1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

269798:CHU RS12960
gene id: 269798:CHU_RS12960
uniprot id: A0A6N4STZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0382 family.
messages: Membrane

269798:CHU RS04665
gene id: 269798:CHU_RS04665
uniprot id: A0A6N4SPI3
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

269798:CHU RS06675
gene id: 269798:CHU_RS06675
uniprot id: A0A6N4SQN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 5 family.
messages: Membrane

269798:CHU RS14640
gene id: 269798:CHU_RS14640
uniprot id: A0A6N4SUQ6
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

269798:CHU RS13085
gene id: 269798:CHU_RS13085
uniprot id: A0A6N4STZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

269798:CHU RS18275
gene id: 269798:CHU_RS18275
uniprot id: A0A6N4SWI0
names: Subcellular Location Annotation
messages: Cytoplasm

269798:CHU RS06980
gene id: 269798:CHU_RS06980
uniprot id: A0A6N4SQY3
names: Domain
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
messages: Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.

269798:CHU RS02475
gene id: 269798:CHU_RS02475
uniprot id: A0A6N4SNE7
names: Similarity
messages: Belongs to the barstar family.

269798:CHU RS13465
gene id: 269798:CHU_RS13465
uniprot id: A0A6N4SUM1
names: Subcellular Location Annotation
messages: Membrane

269798:CHU RS04750
gene id: 269798:CHU_RS04750
uniprot id: A0A6N4SPM6
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

269798:CHU RS12275
gene id: 269798:CHU_RS12275
uniprot id: A0A6N4STL4
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

269798:CHU RS08325
gene id: 269798:CHU_RS08325
uniprot id: A0A6N4SRF3
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

269798:CHU RS00730
gene id: 269798:CHU_RS00730
uniprot id: A0A6N4SME7
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

269798:CHU RS13495
gene id: 269798:CHU_RS13495
uniprot id: A0A6N4SU83
names: Subcellular Location Annotation
messages: Membrane

269798:CHU RS16500
gene id: 269798:CHU_RS16500
uniprot id: A0A6N4SPG6
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

269798:CHU RS06000
gene id: 269798:CHU_RS06000
uniprot id: A0A6N4SQB2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

269798:CHU RS01795
gene id: 269798:CHU_RS01795
uniprot id: A0A6N4SMY6
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

269798:CHU RS12880
gene id: 269798:CHU_RS12880
uniprot id: A0A6N4SU32
names: Subcellular Location Annotation
messages: Membrane

269798:CHU RS13330
gene id: 269798:CHU_RS13330
uniprot id: Q11RH3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

269798:CHU RS16775
gene id: 269798:CHU_RS16775
uniprot id: A0A6N4SVU0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

269798:CHU RS16480
gene id: 269798:CHU_RS16480
uniprot id: A0A6N4SVS1
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

269798:CHU RS07385
gene id: 269798:CHU_RS07385
uniprot id: A0A6N4SR32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Cell membrane
messages: Membrane

269798:CHU RS15680
gene id: 269798:CHU_RS15680
uniprot id: Q11Q55
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

269798:CHU RS05500
gene id: 269798:CHU_RS05500
uniprot id: A0A6N4SQ44
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

269798:CHU RS15570
gene id: 269798:CHU_RS15570
uniprot id: A0A6N4SVI4
names: Similarity
messages: Belongs to the GSP E family.

269798:CHU RS07550
gene id: 269798:CHU_RS07550
uniprot id: A0A6N4SR52
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

269798:CHU RS03800
gene id: 269798:CHU_RS03800
uniprot id: Q11X05
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.

269798:CHU RS14945
gene id: 269798:CHU_RS14945
uniprot id: A0A6N4SV13
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell inner membrane
messages: Cytoplasm
messages: Monomer.

269798:CHU RS13215
gene id: 269798:CHU_RS13215
uniprot id: A0A6N4SUA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

269798:CHU RS12445
gene id: 269798:CHU_RS12445
uniprot id: Q11S04
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell inner membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

269798:CHU RS16040
gene id: 269798:CHU_RS16040
uniprot id: A0A6N4SW38
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

269798:CHU RS08005
gene id: 269798:CHU_RS08005
uniprot id: Q11UK1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

269798:CHU RS17905
gene id: 269798:CHU_RS17905
uniprot id: A0A6N4SWR4
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

269798:CHU RS14765
gene id: 269798:CHU_RS14765
uniprot id: Q11QN6
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

269798:CHU RS07860
gene id: 269798:CHU_RS07860
uniprot id: A0A6N4SR69
names: Subcellular Location Annotation
messages: Membrane

269798:CHU RS16485
gene id: 269798:CHU_RS16485
uniprot id: A0A6N4SW10
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

269798:CHU RS05170
gene id: 269798:CHU_RS05170
uniprot id: A0A6N4SPZ5
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

269798:CHU RS00400
gene id: 269798:CHU_RS00400
uniprot id: A0A6N4SM99
names: Subcellular Location Annotation
messages: Cytoplasm

269798:CHU RS13125
gene id: 269798:CHU_RS13125
uniprot id: A0A6N4SUF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

269798:CHU RS11110
gene id: 269798:CHU_RS11110
uniprot id: A0A6N4ST46
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

269798:CHU RS05015
gene id: 269798:CHU_RS05015
uniprot id: A0A6N4SPP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0394 family.
messages: Membrane

269798:CHU RS11410
gene id: 269798:CHU_RS11410
uniprot id: A0A6N4ST95
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

269798:CHU RS11430
gene id: 269798:CHU_RS11430
uniprot id: A0A6N4STG3
names: Similarity
messages: Belongs to the iron-containing alcohol dehydrogenase family.

269798:CHU RS08345
gene id: 269798:CHU_RS08345
uniprot id: A0A6N4SRF4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

269798:CHU RS02295
gene id: 269798:CHU_RS02295
uniprot id: A0A6N4SNB7
names: Subcellular Location Annotation
messages: Membrane

269798:CHU RS10550
gene id: 269798:CHU_RS10550
uniprot id: A0A6N4SSU4
names: Subcellular Location Annotation
messages: Membrane

269798:CHU RS16960
gene id: 269798:CHU_RS16960
uniprot id: A0A6N4SW08
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

269798:CHU RS13165
gene id: 269798:CHU_RS13165
uniprot id: Q11RK8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. tRNA (adenine-N(6)-)-methyltransferase family.
messages: Cytoplasm
messages: Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC).

269798:CHU RS16905
gene id: 269798:CHU_RS16905
uniprot id: A0A6N4SW72
names: Similarity
messages: Belongs to the ACC deaminase/D-cysteine desulfhydrase family.

269798:CHU RS09480
gene id: 269798:CHU_RS09480
uniprot id: A0A6N4SS85
names: Subcellular Location Annotation
messages: Membrane

269798:CHU RS09420
gene id: 269798:CHU_RS09420
uniprot id: A0A6N4SSA5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An FAD-requiring monooxygenase active on some tetracycline antibiotic derivatives, which leads to their inactivation. Hydroxylates carbon 11a of tetracycline and some analogs.
messages: Belongs to the aromatic-ring hydroxylase family. TetX subfamily.
messages: Consists of an N-terminal FAD-binding domain with a Rossman fold and a C-terminal substrate-binding domain.
messages: Cytoplasm
messages: Monomer.

269798:CHU RS15715
gene id: 269798:CHU_RS15715
uniprot id: A0A6N4SVB9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

269798:CHU RS06365
gene id: 269798:CHU_RS06365
uniprot id: Q11VI6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

269798:CHU RS16100
gene id: 269798:CHU_RS16100
uniprot id: A0A6N4SVS0
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

269798:CHU RS13685
gene id: 269798:CHU_RS13685
uniprot id: A0A6N4SUS1
names: Similarity
messages: Belongs to the glycosyl hydrolase 63 family.

269798:CHU RS14625
gene id: 269798:CHU_RS14625
uniprot id: A0A6N4SUU5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

269798:CHU RS10335
gene id: 269798:CHU_RS10335
uniprot id: A0A6N4SSQ3
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

269798:CHU RS12995
gene id: 269798:CHU_RS12995
uniprot id: Q11RP3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.

269798:CHU RS03850
gene id: 269798:CHU_RS03850
uniprot id: A0A6N4SP30
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

269798:CHU RS03340
gene id: 269798:CHU_RS03340
uniprot id: A0A6N4SNX3
names: Similarity
messages: Belongs to the pirin family.

269798:CHU RS01480
gene id: 269798:CHU_RS01480
uniprot id: A0A6N4SMT4
names: Subcellular Location Annotation
messages: Membrane

269798:CHU RS09000
gene id: 269798:CHU_RS09000
uniprot id: A0A6N4SRU3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

269798:CHU RS04610
gene id: 269798:CHU_RS04610
uniprot id: A0A6N4SPH1
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

269798:CHU RS03300
gene id: 269798:CHU_RS03300
uniprot id: A0A6N4SNS3
names: Subcellular Location Annotation
messages: Membrane

269798:CHU RS12805
gene id: 269798:CHU_RS12805
uniprot id: A0A6N4SU89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Membrane

269798:CHU RS06690
gene id: 269798:CHU_RS06690
uniprot id: Q11VC0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

269798:CHU RS15935
gene id: 269798:CHU_RS15935
uniprot id: A0A6N4SW47
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell inner membrane
messages: Probably interacts with PlsX.

269798:CHU RS10740
gene id: 269798:CHU_RS10740
uniprot id: A0A6N4SSR9
names: Subcellular Location Annotation
messages: Membrane

269798:CHU RS16495
gene id: 269798:CHU_RS16495
uniprot id: A0A6N4SVN8
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily.

269798:CHU RS06505
gene id: 269798:CHU_RS06505
uniprot id: A0A6N4SQK1
names: Similarity
messages: Belongs to the glycosyl hydrolase 9 (cellulase E) family.

269798:CHU RS07505
gene id: 269798:CHU_RS07505
uniprot id: A0A6N4SRA5
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

269798:CHU RS16840
gene id: 269798:CHU_RS16840
uniprot id: A0A6N4SVR8
names: Similarity
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Belongs to the peroxiredoxin family. Prx6 subfamily.

269798:CHU RS19175
gene id: 269798:CHU_RS19175
uniprot id: Q11UM1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

269798:CHU RS02665
gene id: 269798:CHU_RS02665
uniprot id: A0A6N4SNH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

269798:CHU RS16405
gene id: 269798:CHU_RS16405
uniprot id: A0A6N4SVJ4
names: Similarity
messages: Belongs to the RutC family.

269798:CHU RS08660
gene id: 269798:CHU_RS08660
uniprot id: Q11U74
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

269798:CHU RS05270
gene id: 269798:CHU_RS05270
uniprot id: A0A6N4SPX8
names: Similarity
messages: Belongs to the ClpA/ClpB family.

269798:CHU RS06450
gene id: 269798:CHU_RS06450
uniprot id: A0A6N4SQM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

269798:CHU RS07300
gene id: 269798:CHU_RS07300
uniprot id: A0A6N4SQW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

269798:CHU RS13100
gene id: 269798:CHU_RS13100
uniprot id: Q11RM1
names: Function
names: Similarity
messages: Belongs to the TrhO family.
messages: Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.

269798:CHU RS18725
gene id: 269798:CHU_RS18725
uniprot id: A0A6N4SN21
names: Similarity
messages: Belongs to the glycosyl hydrolase 26 family.

269798:CHU RS01810
gene id: 269798:CHU_RS01810
uniprot id: Q11Y69
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain.

269798:CHU RS12480
gene id: 269798:CHU_RS12480
uniprot id: A0A6N4SU31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

269798:CHU RS01515
gene id: 269798:CHU_RS01515
uniprot id: A0A6N4SMS5
names: Similarity
messages: Belongs to the GARS family.

269798:CHU RS14760
gene id: 269798:CHU_RS14760
uniprot id: Q11QN7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

269798:CHU RS15035
gene id: 269798:CHU_RS15035
uniprot id: A0A6N4SV93
names: Subcellular Location Annotation
messages: Membrane

269798:CHU RS15005
gene id: 269798:CHU_RS15005
uniprot id: Q11QI8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

269798:CHU RS13140
gene id: 269798:CHU_RS13140
uniprot id: A0A6N4SUE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Membrane

269798:CHU RS06200
gene id: 269798:CHU_RS06200
uniprot id: Q11VM1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

269798:CHU RS11845
gene id: 269798:CHU_RS11845
uniprot id: A0A6N4STE2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

269798:CHU RS11205
gene id: 269798:CHU_RS11205
uniprot id: A0A6N4ST62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

269798:CHU RS02095
gene id: 269798:CHU_RS02095
uniprot id: A0A6N4SN42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

269798:CHU RS14905
gene id: 269798:CHU_RS14905
uniprot id: A0A6N4SUZ3
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A lyase-type mechanism (elimination/hydration) is suggested for the cleavage of the lactyl ether bond of MurNAc 6-phosphate, with the formation of an alpha,beta-unsaturated aldehyde intermediate with (E)-stereochemistry, followed by the syn addition of water to give product.
messages: Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.
messages: Homodimer.
messages: Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate.

269798:CHU RS09830
gene id: 269798:CHU_RS09830
uniprot id: A0A6N4SSH2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

269798:CHU RS18080
gene id: 269798:CHU_RS18080
uniprot id: A0A6N4SX00
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

269798:CHU RS09265
gene id: 269798:CHU_RS09265
uniprot id: A0A6N4SS17
names: Caution
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
messages: Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

269798:CHU RS12845
gene id: 269798:CHU_RS12845
uniprot id: A0A6N4STX8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the trans-sulfuration enzymes family. MetZ subfamily.
messages: Catalyzes the formation of L-homocysteine from O-succinyl-L-homoserine (OSHS) and hydrogen sulfide.
messages: Homotetramer.

269798:CHU RS15965
gene id: 269798:CHU_RS15965
uniprot id: A0A6N4SVI3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

269798:CHU RS04245
gene id: 269798:CHU_RS04245
uniprot id: A0A6N4SPE0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

269798:CHU RS09020
gene id: 269798:CHU_RS09020
uniprot id: A0A6N4SS53
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

269798:CHU RS16015
gene id: 269798:CHU_RS16015
uniprot id: Q11PY2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.

269798:CHU RS06270
gene id: 269798:CHU_RS06270
uniprot id: Q11VK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

269798:CHU RS17380
gene id: 269798:CHU_RS17380
uniprot id: A0A6N4SWF1
names: Subcellular Location Annotation
messages: Membrane

269798:CHU RS13455
gene id: 269798:CHU_RS13455
uniprot id: A0A6N4SU71
names: Similarity
messages: Belongs to the polysaccharide synthase family.

269798:CHU RS07995
gene id: 269798:CHU_RS07995
uniprot id: Q11UK3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also edits incorrectly charged L-seryl-tRNA(Thr).
messages: Cytoplasm
messages: Homodimer.

269798:CHU RS06640
gene id: 269798:CHU_RS06640
uniprot id: A0A6N4SQM0
names: Similarity
messages: Belongs to the peptidase S13 family.

269798:CHU RS12725
gene id: 269798:CHU_RS12725
uniprot id: A0A6N4STV9
names: Subcellular Location Annotation
messages: Membrane

269798:CHU RS18195
gene id: 269798:CHU_RS18195
uniprot id: A0A6N4SX23
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

269798:CHU RS17490
gene id: 269798:CHU_RS17490
uniprot id: A0A6N4SWI9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

269798:CHU RS17725
gene id: 269798:CHU_RS17725
uniprot id: A0A6N4SX87
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

269798:CHU RS05305
gene id: 269798:CHU_RS05305
uniprot id: A0A6N4SPY5
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

269798:CHU RS07745
gene id: 269798:CHU_RS07745
uniprot id: A0A6N4SRE5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

269798:CHU RS17370
gene id: 269798:CHU_RS17370
uniprot id: A0A6N4SWT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

269798:CHU RS07705
gene id: 269798:CHU_RS07705
uniprot id: A0A6N4SRE8
names: Similarity
messages: Belongs to the 4-oxalocrotonate tautomerase family.

269798:CHU RS16600
gene id: 269798:CHU_RS16600
uniprot id: A0A6N4SVT8
names: Similarity
messages: Belongs to the Skp family.

269798:CHU RS07725
gene id: 269798:CHU_RS07725
uniprot id: A0A6N4SR67
names: Similarity
messages: Belongs to the ArsC family.

269798:CHU RS00080
gene id: 269798:CHU_RS00080
uniprot id: A0A6N4SM39
names: Subcellular Location Annotation
messages: Membrane

269798:CHU RS08900
gene id: 269798:CHU_RS08900
uniprot id: Q11U26
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

269798:CHU RS06195
gene id: 269798:CHU_RS06195
uniprot id: Q11VM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

269798:CHU RS10005
gene id: 269798:CHU_RS10005
uniprot id: A0A6N4SSH5
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

269798:CHU RS04635
gene id: 269798:CHU_RS04635
uniprot id: A0A6N4SPN4
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

269798:CHU RS04525
gene id: 269798:CHU_RS04525
uniprot id: Q11WK6
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

269798:CHU RS09930
gene id: 269798:CHU_RS09930
uniprot id: Q11TG8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.

269798:CHU RS13705
gene id: 269798:CHU_RS13705
uniprot id: A0A6N4SUR3
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

269798:CHU RS08935
gene id: 269798:CHU_RS08935
uniprot id: Q11U19
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

269798:CHU RS04530
gene id: 269798:CHU_RS04530
uniprot id: Q11WK5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

269798:CHU RS04035
gene id: 269798:CHU_RS04035
uniprot id: A0A6N4SP97
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

269798:CHU RS18070
gene id: 269798:CHU_RS18070
uniprot id: Q11NR0
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

269798:CHU RS06135
gene id: 269798:CHU_RS06135
uniprot id: A0A6N4SQA2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease beta subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

269798:CHU RS12180
gene id: 269798:CHU_RS12180
uniprot id: A0A6N4SU61
names: Similarity
messages: Belongs to the glutamine synthetase family.

269798:CHU RS11215
gene id: 269798:CHU_RS11215
uniprot id: A0A6N4ST54
names: Similarity
messages: Belongs to the AHA1 family.

269798:CHU RS13775
gene id: 269798:CHU_RS13775
uniprot id: A0A6N4SUC6
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF2.
messages: Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.

269798:CHU RS12615
gene id: 269798:CHU_RS12615
uniprot id: Q11RW8
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

269798:CHU RS04615
gene id: 269798:CHU_RS04615
uniprot id: Q11WJ0
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell inner membrane

269798:CHU RS09985
gene id: 269798:CHU_RS09985
uniprot id: A0A6N4SS90
names: Similarity
messages: Belongs to the glycosyl hydrolase 30 family.

269798:CHU RS05825
gene id: 269798:CHU_RS05825
uniprot id: A0A6N4SQA8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

269798:CHU RS00375
gene id: 269798:CHU_RS00375
uniprot id: A0A6N4SM98
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

269798:CHU RS13350
gene id: 269798:CHU_RS13350
uniprot id: Q11RG9
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm

269798:CHU RS10270
gene id: 269798:CHU_RS10270
uniprot id: A0A6N4SSH1
names: Similarity
messages: Belongs to the glycosyl hydrolase 10 (cellulase F) family.

269798:CHU RS08725
gene id: 269798:CHU_RS08725
uniprot id: Q11U61
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

269798:CHU RS06645
gene id: 269798:CHU_RS06645
uniprot id: A0A6N4SQS0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DtxR/MntR family.
messages: Cytoplasm
messages: Homodimer.

269798:CHU RS14470
gene id: 269798:CHU_RS14470
uniprot id: A0A6N4SUN6
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

269798:CHU RS05530
gene id: 269798:CHU_RS05530
uniprot id: A0A6N4SQ08
names: Subcellular Location Annotation
messages: Membrane

269798:CHU RS05220
gene id: 269798:CHU_RS05220
uniprot id: A0A6N4SPW5
names: Subcellular Location Annotation
messages: Membrane

269798:CHU RS08735
gene id: 269798:CHU_RS08735
uniprot id: A0A6N4SRV9
names: Subcellular Location Annotation
messages: Membrane

269798:CHU RS06360
gene id: 269798:CHU_RS06360
uniprot id: A0A6N4SQN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

269798:CHU RS06550
gene id: 269798:CHU_RS06550
uniprot id: A0A6N4SQP9
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.

269798:CHU RS04655
gene id: 269798:CHU_RS04655
uniprot id: A0A6N4SPG7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.
messages: Cytoplasm

269798:CHU RS03900
gene id: 269798:CHU_RS03900
uniprot id: A0A6N4SP38
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

269798:CHU RS13485
gene id: 269798:CHU_RS13485
uniprot id: Q11RE0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Monomer.

269798:CHU RS15470
gene id: 269798:CHU_RS15470
uniprot id: Q11Q97
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

269798:CHU RS03600
gene id: 269798:CHU_RS03600
uniprot id: A0A6N4SNY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

269798:CHU RS06770
gene id: 269798:CHU_RS06770
uniprot id: A0A6N4SQU0
names: Function
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

269798:CHU RS01815
gene id: 269798:CHU_RS01815
uniprot id: A0A6N4SN09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

269798:CHU RS17710
gene id: 269798:CHU_RS17710
uniprot id: A0A6N4SWR6
names: Similarity
messages: Belongs to the NDK family.

269798:CHU RS11825
gene id: 269798:CHU_RS11825
uniprot id: A0A6N4STA2
names: Function
names: Similarity
messages: Belongs to the peptidase S46 family.
messages: Catalyzes the removal of dipeptides from the N-terminus of oligopeptides.

269798:CHU RS04540
gene id: 269798:CHU_RS04540
uniprot id: Q11WK3
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

269798:CHU RS01640
gene id: 269798:CHU_RS01640
uniprot id: A0A6N4SMW4
names: Function
names: Similarity
messages: Belongs to the transglycosylase MltG family.
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

269798:CHU RS08875
gene id: 269798:CHU_RS08875
uniprot id: A0A6N4SRR2
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

269798:CHU RS04980
gene id: 269798:CHU_RS04980
uniprot id: A0A6N4SPT4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

269798:CHU RS03360
gene id: 269798:CHU_RS03360
uniprot id: A0A6N4SNV5
names: Similarity
messages: Belongs to the DinB family.

269798:CHU RS16680
gene id: 269798:CHU_RS16680
uniprot id: A0A6N4SW90
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

269798:CHU RS05870
gene id: 269798:CHU_RS05870
uniprot id: A0A6N4SQ56
names: Similarity
messages: Belongs to the peptidase M4 family.

269798:CHU RS07030
gene id: 269798:CHU_RS07030
uniprot id: A0A6N4SQZ2
names: Similarity
messages: Belongs to the DprA/Smf family.

269798:CHU RS09145
gene id: 269798:CHU_RS09145
uniprot id: A0A6N4SS63
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

269798:CHU RS03985
gene id: 269798:CHU_RS03985
uniprot id: A0A6N4SP85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YejK family.
messages: nucleoid

269798:CHU RS09900
gene id: 269798:CHU_RS09900
uniprot id: A0A6N4SSG8
names: Similarity
messages: Belongs to the DtxR/MntR family.

269798:CHU RS09885
gene id: 269798:CHU_RS09885
uniprot id: A0A6N4SS92
names: Similarity
messages: Belongs to the Dps family.

269798:CHU RS01800
gene id: 269798:CHU_RS01800
uniprot id: Q11Y71
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SIS family. GmhA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
messages: Cytoplasm
messages: The reaction produces a racemic mixture of D-glycero-alpha-D-manno-heptose 7-phosphate and D-glycero-beta-D-manno-heptose 7-phosphate.

269798:CHU RS02840
gene id: 269798:CHU_RS02840
uniprot id: A0A6N4SNK2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.

269798:CHU RS00140
gene id: 269798:CHU_RS00140
uniprot id: A0A6N4SM47
names: Similarity
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the malic enzymes family.

269798:CHU RS03200
gene id: 269798:CHU_RS03200
uniprot id: Q11XD1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

269798:CHU RS03240
gene id: 269798:CHU_RS03240
uniprot id: A0A6N4SNQ1
names: Similarity
messages: Belongs to the GHMP kinase family. GalK subfamily.

269798:CHU RS12105
gene id: 269798:CHU_RS12105
uniprot id: A0A6N4STP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family.
messages: Membrane

269798:CHU RS06935
gene id: 269798:CHU_RS06935
uniprot id: A0A6N4SQT1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

269798:CHU RS04490
gene id: 269798:CHU_RS04490
uniprot id: A0A6N4SPG5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Cell wall formation.
messages: Cytoplasm

269798:CHU RS00060
gene id: 269798:CHU_RS00060
uniprot id: A0A6N4SM24
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

269798:CHU RS06390
gene id: 269798:CHU_RS06390
uniprot id: Q11VI1
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

269798:CHU RS11015
gene id: 269798:CHU_RS11015
uniprot id: A0A6N4ST24
names: Similarity
messages: Belongs to the band 7/mec-2 family. Flotillin subfamily.

269798:CHU RS15740
gene id: 269798:CHU_RS15740
uniprot id: A0A6N4SW07
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

269798:CHU RS17615
gene id: 269798:CHU_RS17615
uniprot id: A0A6N4SX57
names: Subcellular Location Annotation
messages: Membrane

269798:CHU RS14990
gene id: 269798:CHU_RS14990
uniprot id: A0A6N4SV80
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

269798:CHU RS13370
gene id: 269798:CHU_RS13370
uniprot id: Q11RG5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

269798:CHU RS16465
gene id: 269798:CHU_RS16465
uniprot id: A0A6N4SVP7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

269798:CHU RS06155
gene id: 269798:CHU_RS06155
uniprot id: Q11VN0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UreD family.
messages: Cytoplasm
messages: Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
messages: UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

269798:CHU RS04905
gene id: 269798:CHU_RS04905
uniprot id: A0A6N4SPU7
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

269798:CHU RS17955
gene id: 269798:CHU_RS17955
uniprot id: A0A6N4SWS4
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

269798:CHU RS08385
gene id: 269798:CHU_RS08385
uniprot id: Q11UD1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

269798:CHU RS16635
gene id: 269798:CHU_RS16635
uniprot id: A0A6N4SWF4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

269798:CHU RS09230
gene id: 269798:CHU_RS09230
uniprot id: A0A6N4SRX1
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

269798:CHU RS07755
gene id: 269798:CHU_RS07755
uniprot id: A0A6N4SR92
names: Subcellular Location Annotation
messages: Membrane

269798:CHU RS04050
gene id: 269798:CHU_RS04050
uniprot id: A0A6N4SPD1
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

269798:CHU RS15295
gene id: 269798:CHU_RS15295
uniprot id: A0A6N4SVC7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

269798:CHU RS06985
gene id: 269798:CHU_RS06985
uniprot id: A0A6N4SQU6
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

269798:CHU RS13620
gene id: 269798:CHU_RS13620
uniprot id: A0A6N4SUI8
names: Similarity
messages: Belongs to the glycosyl hydrolase 16 family.

269798:CHU RS09905
gene id: 269798:CHU_RS09905
uniprot id: A0A6N4SSB9
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

269798:CHU RS04670
gene id: 269798:CHU_RS04670
uniprot id: A0A6N4SPL5
names: Subcellular Location Annotation
messages: Membrane

269798:CHU RS06470
gene id: 269798:CHU_RS06470
uniprot id: A0A6N4SQG3
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

269798:CHU RS18085
gene id: 269798:CHU_RS18085
uniprot id: A0A6N4SX40
names: Subcellular Location Annotation
messages: Membrane

269798:CHU RS07865
gene id: 269798:CHU_RS07865
uniprot id: A0A6N4SRA9
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

269798:CHU RS15255
gene id: 269798:CHU_RS15255
uniprot id: Q11QD6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

269798:CHU RS12290
gene id: 269798:CHU_RS12290
uniprot id: A0A6N4STJ7
names: Similarity
messages: Belongs to the peptidase S8 family.

269798:CHU RS16845
gene id: 269798:CHU_RS16845
uniprot id: A0A6N4SW37
names: Similarity
messages: Belongs to the Skp family.

269798:CHU RS00175
gene id: 269798:CHU_RS00175
uniprot id: A0A6N4SM43
names: Similarity
messages: Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family.

269798:CHU RS05455
gene id: 269798:CHU_RS05455
uniprot id: A0A6N4SQ17
names: Similarity
messages: Belongs to the AHA1 family.

269798:CHU RS02090
gene id: 269798:CHU_RS02090
uniprot id: A0A6N4SN53
names: Similarity
messages: Belongs to the calycin superfamily. Lipocalin family.

269798:CHU RS17420
gene id: 269798:CHU_RS17420
uniprot id: A0A6N4SWU5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

269798:CHU RS07920
gene id: 269798:CHU_RS07920
uniprot id: Q11UL8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

269798:CHU RS16515
gene id: 269798:CHU_RS16515
uniprot id: Q11PN0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

269798:CHU RS18200
gene id: 269798:CHU_RS18200
uniprot id: Q11NN5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.

269798:CHU RS09350
gene id: 269798:CHU_RS09350
uniprot id: A0A6N4SRY7
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

269798:CHU RS16380
gene id: 269798:CHU_RS16380
uniprot id: A0A6N4SW35
names: Subunit
messages: Monomer.

269798:CHU RS05815
gene id: 269798:CHU_RS05815
uniprot id: A0A6N4SQD1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

269798:CHU RS01890
gene id: 269798:CHU_RS01890
uniprot id: Q11Y53
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvB family.
messages: Forms a complex with RuvA.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.

269798:CHU RS11760
gene id: 269798:CHU_RS11760
uniprot id: A0A6N4STY3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.

269798:CHU RS00655
gene id: 269798:CHU_RS00655
uniprot id: Q11YU5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell inner membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

269798:CHU RS16630
gene id: 269798:CHU_RS16630
uniprot id: Q11PK7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

269798:CHU RS17235
gene id: 269798:CHU_RS17235
uniprot id: A0A6N4SWU9
names: Subcellular Location Annotation
messages: Membrane

269798:CHU RS00310
gene id: 269798:CHU_RS00310
uniprot id: A0A6N4SM76
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. Fucose synthase subfamily.
messages: Catalyzes the two-step NADP-dependent conversion of GDP-4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction.

269798:CHU RS12005
gene id: 269798:CHU_RS12005
uniprot id: A0A6N4STL6
names: Similarity
messages: Belongs to the fabD family.

269798:CHU RS06530
gene id: 269798:CHU_RS06530
uniprot id: A0A6N4SQR2
names: Similarity
messages: Belongs to the class I fructose-bisphosphate aldolase family.

269798:CHU RS07360
gene id: 269798:CHU_RS07360
uniprot id: A0A6N4SR75
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

269798:CHU RS00130
gene id: 269798:CHU_RS00130
uniprot id: A0A6N4SM49
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

269798:CHU RS16955
gene id: 269798:CHU_RS16955
uniprot id: A0A6N4SW81
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Cytoplasm

269798:CHU RS08000
gene id: 269798:CHU_RS08000
uniprot id: A0A6N4SRC2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-3 family.
messages: Cytoplasm
messages: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
messages: Monomer.

269798:CHU RS12610
gene id: 269798:CHU_RS12610
uniprot id: Q11RW9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

269798:CHU RS14875
gene id: 269798:CHU_RS14875
uniprot id: A0A6N4SUX7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.

269798:CHU RS18100
gene id: 269798:CHU_RS18100
uniprot id: A0A6N4SXB5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell inner membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

269798:CHU RS03385
gene id: 269798:CHU_RS03385
uniprot id: A0A6N4SNV8
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

269798:CHU RS00075
gene id: 269798:CHU_RS00075
uniprot id: Q11Z58
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

269798:CHU RS12765
gene id: 269798:CHU_RS12765
uniprot id: A0A6N4SU13
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

269798:CHU RS15815
gene id: 269798:CHU_RS15815
uniprot id: A0A6N4SVJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmB/CycW/HelB family.
messages: Membrane

269798:CHU RS01860
gene id: 269798:CHU_RS01860
uniprot id: A0A6N4SN07
names: Subcellular Location Annotation
messages: Membrane

269798:CHU RS18430
gene id: 269798:CHU_RS18430
uniprot id: A0A6N4SX39
names: Similarity
messages: Belongs to the thiolase-like superfamily. Chalcone/stilbene synthases family.

269798:CHU RS15380
gene id: 269798:CHU_RS15380
uniprot id: Q11QB1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

269798:CHU RS00045
gene id: 269798:CHU_RS00045
uniprot id: Q11Z64
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

269798:CHU RS17600
gene id: 269798:CHU_RS17600
uniprot id: A0A6N4SWP7
names: Subcellular Location Annotation
messages: Membrane

269798:CHU RS17445
gene id: 269798:CHU_RS17445
uniprot id: A0A6N4SWA1
names: Similarity
messages: Belongs to the ArsC family.

269798:CHU RS12260
gene id: 269798:CHU_RS12260
uniprot id: A0A6N4STM4
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

269798:CHU RS02330
gene id: 269798:CHU_RS02330
uniprot id: A0A6N4SN93
names: Cofactor
messages: Binds 1 zinc ion per subunit.

269798:CHU RS15140
gene id: 269798:CHU_RS15140
uniprot id: A0A6N4SVA8
names: Similarity
messages: Belongs to the DEAD box helicase family.

269798:CHU RS01060
gene id: 269798:CHU_RS01060
uniprot id: A0A6N4SML3
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

269798:CHU RS06500
gene id: 269798:CHU_RS06500
uniprot id: A0A6N4SQN4
names: Similarity
messages: Belongs to the glycosyl hydrolase 9 (cellulase E) family.

269798:CHU RS15390
gene id: 269798:CHU_RS15390
uniprot id: Q11QA9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

269798:CHU RS16725
gene id: 269798:CHU_RS16725
uniprot id: A0A6N4SW40
names: Similarity
messages: Belongs to the glycosyl hydrolase 8 (cellulase D) family.

269798:CHU RS18655
gene id: 269798:CHU_RS18655
uniprot id: A0A6N4SXN5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

269798:CHU RS06685
gene id: 269798:CHU_RS06685
uniprot id: A0A6N4SQU4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

269798:CHU RS08315
gene id: 269798:CHU_RS08315
uniprot id: A0A6N4SRK0
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

269798:CHU RS17850
gene id: 269798:CHU_RS17850
uniprot id: Q11NV4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

269798:CHU RS02250
gene id: 269798:CHU_RS02250
uniprot id: A0A6N4SN99
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

269798:CHU RS17780
gene id: 269798:CHU_RS17780
uniprot id: A0A6N4SX33
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mediates influx of magnesium ions.
messages: Membrane

269798:CHU RS02020
gene id: 269798:CHU_RS02020
uniprot id: A0A6N4SN46
names: Similarity
messages: Belongs to the glycosyltransferase 20 family.
messages: In the C-terminal section; belongs to the trehalose phosphatase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 20 family.

269798:CHU RS05300
gene id: 269798:CHU_RS05300
uniprot id: A0A6N4SPY1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

269798:CHU RS02595
gene id: 269798:CHU_RS02595
uniprot id: A0A6N4SNE8
names: Cofactor
names: PTM
names: Subcellular Location Annotation
messages: Binds 2 heme groups per subunit.
messages: Binds 2 heme groups.
messages: Periplasm

269798:CHU RS13480
gene id: 269798:CHU_RS13480
uniprot id: Q11RE2
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homotetramer.

269798:CHU RS14700
gene id: 269798:CHU_RS14700
uniprot id: A0A6N4SV32
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

269798:CHU RS09805
gene id: 269798:CHU_RS09805
uniprot id: Q11TJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

269798:CHU RS15335
gene id: 269798:CHU_RS15335
uniprot id: Q11QC0
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

269798:CHU RS02320
gene id: 269798:CHU_RS02320
uniprot id: Q11XW2
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

269798:CHU RS04845
gene id: 269798:CHU_RS04845
uniprot id: A0A6N4SPK8
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.

269798:CHU RS05410
gene id: 269798:CHU_RS05410
uniprot id: A0A6N4SQ07
names: Similarity
messages: Belongs to the AHA1 family.

269798:CHU RS17375
gene id: 269798:CHU_RS17375
uniprot id: A0A6N4SW17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

269798:CHU RS18640
gene id: 269798:CHU_RS18640
uniprot id: A0A6N4SWY2
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

269798:CHU RS15230
gene id: 269798:CHU_RS15230
uniprot id: Q11QE1
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

269798:CHU RS13550
gene id: 269798:CHU_RS13550
uniprot id: Q11RC7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

269798:CHU RS06705
gene id: 269798:CHU_RS06705
uniprot id: A0A6N4SQS8
names: Function
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

269798:CHU RS06420
gene id: 269798:CHU_RS06420
uniprot id: A0A6N4SQF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
messages: Cell membrane
messages: Membrane

269798:CHU RS10475
gene id: 269798:CHU_RS10475
uniprot id: Q11T54
names: Function
names: Similarity
messages: Belongs to the SELO family.
messages: Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).

269798:CHU RS17105
gene id: 269798:CHU_RS17105
uniprot id: A0A6N4SW89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OmpP1/FadL family.
messages: Cell outer membrane
messages: Membrane

269798:CHU RS13375
gene id: 269798:CHU_RS13375
uniprot id: A0A6N4SUT5
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

269798:CHU RS09705
gene id: 269798:CHU_RS09705
uniprot id: A0A6N4SSA6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpC family.
messages: Cell inner membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

269798:CHU RS04550
gene id: 269798:CHU_RS04550
uniprot id: Q11WK1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

269798:CHU RS11165
gene id: 269798:CHU_RS11165
uniprot id: A0A6N4ST44
names: Similarity
messages: Belongs to the disproportionating enzyme family.

269798:CHU RS02325
gene id: 269798:CHU_RS02325
uniprot id: Q11XW1
names: Similarity
messages: Belongs to the UPF0102 family.

269798:CHU RS03425
gene id: 269798:CHU_RS03425
uniprot id: A0A6N4SNV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0187 family.
messages: Membrane

269798:CHU RS16910
gene id: 269798:CHU_RS16910
uniprot id: A0A6N4SVZ8
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

269798:CHU RS14955
gene id: 269798:CHU_RS14955
uniprot id: A0A6N4SVF3
names: Similarity
messages: Belongs to the peptidase S24 family.

269798:CHU RS12595
gene id: 269798:CHU_RS12595
uniprot id: A0A6N4STQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

269798:CHU RS03440
gene id: 269798:CHU_RS03440
uniprot id: A0A6N4SNW8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

269798:CHU RS02375
gene id: 269798:CHU_RS02375
uniprot id: A0A6N4SNA4
names: Similarity
messages: Belongs to the heat shock protein 90 family.

269798:CHU RS18875
gene id: 269798:CHU_RS18875
uniprot id: A0A6N4SRV6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

269798:CHU RS07110
gene id: 269798:CHU_RS07110
uniprot id: A0A6N4SQT2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell inner membrane
messages: Forms a complex with TatC.
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.

269798:CHU RS10075
gene id: 269798:CHU_RS10075
uniprot id: A0A6N4SSN9
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

269798:CHU RS08855
gene id: 269798:CHU_RS08855
uniprot id: A0A6N4SS20
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

269798:CHU RS05040
gene id: 269798:CHU_RS05040
uniprot id: A0A6N4SPT6
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.

269798:CHU RS16555
gene id: 269798:CHU_RS16555
uniprot id: A0A6N4SW69
names: Subcellular Location Annotation
messages: Membrane

269798:CHU RS12720
gene id: 269798:CHU_RS12720
uniprot id: A0A6N4SU14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

269798:CHU RS06425
gene id: 269798:CHU_RS06425
uniprot id: A0A6N4SQJ1
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.

269798:CHU RS05830
gene id: 269798:CHU_RS05830
uniprot id: A0A6N4SQ68
names: Subcellular Location Annotation
messages: Membrane

269798:CHU RS00095
gene id: 269798:CHU_RS00095
uniprot id: A0A6N4SM37
names: Subcellular Location Annotation
messages: Membrane

269798:CHU RS11475
gene id: 269798:CHU_RS11475
uniprot id: A0A6N4ST43
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

269798:CHU RS08135
gene id: 269798:CHU_RS08135
uniprot id: A0A6N4SRG6
names: Cofactor
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.

269798:CHU RS05805
gene id: 269798:CHU_RS05805
uniprot id: A0A6N4SQ77
names: Similarity
messages: Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family. Bacterial alpha-2-macroglobulin subfamily.

269798:CHU RS13090
gene id: 269798:CHU_RS13090
uniprot id: Q11RM3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.

269798:CHU RS18340
gene id: 269798:CHU_RS18340
uniprot id: A0A6N4SX61
names: Similarity
messages: Belongs to the glutamate synthase family.

269798:CHU RS00920
gene id: 269798:CHU_RS00920
uniprot id: Q11YP9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

269798:CHU RS00775
gene id: 269798:CHU_RS00775
uniprot id: A0A6N4SME9
names: Similarity
messages: In the N-terminal section; belongs to the phytochrome family.

269798:CHU RS14840
gene id: 269798:CHU_RS14840
uniprot id: A0A6N4SV69
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial microcompartment
messages: Belongs to the EutC family.
messages: Binds between the large and small subunits.
messages: Catalyzes the deamination of various vicinal amino-alcohols to oxo compounds. Allows this organism to utilize ethanolamine as the sole source of nitrogen and carbon in the presence of external vitamin B12.
messages: The basic unit is a heterodimer which dimerizes to form tetramers. The heterotetramers trimerize; 6 large subunits form a core ring with 6 small subunits projecting outwards.

269798:CHU RS10555
gene id: 269798:CHU_RS10555
uniprot id: A0A6N4SSP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

269798:CHU RS07615
gene id: 269798:CHU_RS07615
uniprot id: A0A6N4SRB3
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

269798:CHU RS08180
gene id: 269798:CHU_RS08180
uniprot id: A0A6N4SRH8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

269798:CHU RS05080
gene id: 269798:CHU_RS05080
uniprot id: A0A6N4SPR6
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

269798:CHU RS18560
gene id: 269798:CHU_RS18560
uniprot id: A0A6N4SWP2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

269798:CHU RS14805
gene id: 269798:CHU_RS14805
uniprot id: Q11QM8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

269798:CHU RS09170
gene id: 269798:CHU_RS09170
uniprot id: Q11TX2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell inner membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

269798:CHU RS18190
gene id: 269798:CHU_RS18190
uniprot id: Q11NN7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

269798:CHU RS18540
gene id: 269798:CHU_RS18540
uniprot id: A0A6N4SX14
names: Function
names: Similarity
messages: Belongs to the PstS family.
messages: Involved in the system for phosphate transport across the cytoplasmic membrane.

269798:CHU RS11115
gene id: 269798:CHU_RS11115
uniprot id: Q11SS5
names: Similarity
messages: Belongs to the UPF0234 family.

269798:CHU RS00470
gene id: 269798:CHU_RS00470
uniprot id: A0A6N4SMA9
names: Similarity
messages: Belongs to the thioredoxin family.

269798:CHU RS04450
gene id: 269798:CHU_RS04450
uniprot id: A0A6N4SPD6
names: Similarity
messages: Belongs to the P(II) protein family.

269798:CHU RS06660
gene id: 269798:CHU_RS06660
uniprot id: A0A6N4SQT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

269798:CHU RS04370
gene id: 269798:CHU_RS04370
uniprot id: A0A6N4SPD3
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily.

269798:CHU RS00155
gene id: 269798:CHU_RS00155
uniprot id: Q11Z42
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

269798:CHU RS00650
gene id: 269798:CHU_RS00650
uniprot id: A0A6N4SMC2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

269798:CHU RS04650
gene id: 269798:CHU_RS04650
uniprot id: A0A6N4SPP8
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.

269798:CHU RS10640
gene id: 269798:CHU_RS10640
uniprot id: A0A6N4SSQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

269798:CHU RS14745
gene id: 269798:CHU_RS14745
uniprot id: A0A6N4SUS4
names: Similarity
messages: Belongs to the peptidase S8 family.