266748:EL218 RS05350
gene id: 266748:EL218_RS05350
uniprot id: A0A448NQA6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 30 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

266748:EL218 RS05000
gene id: 266748:EL218_RS05000
uniprot id: A0A3S4VE79
names: Similarity
messages: Belongs to the thiolase-like superfamily. Chalcone/stilbene synthases family.

266748:EL218 RS00010
gene id: 266748:EL218_RS00010
uniprot id: A0A448NM28
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

266748:EL218 RS06215
gene id: 266748:EL218_RS06215
uniprot id: A0A3S4ULX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0394 family.
messages: Membrane

266748:EL218 RS14120
gene id: 266748:EL218_RS14120
uniprot id: A0A3S4W6G2
names: Similarity
messages: Belongs to the peptidase M1 family.

266748:EL218 RS05540
gene id: 266748:EL218_RS05540
uniprot id: A0A3S4USQ8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: In the C-terminal section; belongs to the OMP decarboxylase family.
messages: In the N-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

266748:EL218 RS05235
gene id: 266748:EL218_RS05235
uniprot id: A0A3S4YSG7
names: Similarity
messages: Belongs to the peptidase M17 family.

266748:EL218 RS12420
gene id: 266748:EL218_RS12420
uniprot id: A0A3S4YUP4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

266748:EL218 RS01130
gene id: 266748:EL218_RS01130
uniprot id: A0A448NMS5
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

266748:EL218 RS05315
gene id: 266748:EL218_RS05315
uniprot id: A0A3S4VEB8
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

266748:EL218 RS00350
gene id: 266748:EL218_RS00350
uniprot id: A0A3S4YP35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

266748:EL218 RS03035
gene id: 266748:EL218_RS03035
uniprot id: A0A448NNY9
names: Similarity
messages: Belongs to the band 7/mec-2 family. Flotillin subfamily.

266748:EL218 RS10915
gene id: 266748:EL218_RS10915
uniprot id: A0A448NTA6
names: Function
names: Similarity
messages: Belongs to the peptidase S46 family.
messages: Catalyzes the removal of dipeptides from the N-terminus of oligopeptides.

266748:EL218 RS04260
gene id: 266748:EL218_RS04260
uniprot id: A0A3S4UWR4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

266748:EL218 RS12360
gene id: 266748:EL218_RS12360
uniprot id: A0A3S4YLH8
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

266748:EL218 RS14255
gene id: 266748:EL218_RS14255
uniprot id: A0A3S4YM24
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

266748:EL218 RS01520
gene id: 266748:EL218_RS01520
uniprot id: A0A448NMY4
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

266748:EL218 RS07630
gene id: 266748:EL218_RS07630
uniprot id: A0A448NRF2
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

266748:EL218 RS07115
gene id: 266748:EL218_RS07115
uniprot id: A0A448NR11
names: Similarity
messages: Belongs to the Dps family.

266748:EL218 RS06295
gene id: 266748:EL218_RS06295
uniprot id: A0A448NQQ4
names: Similarity
messages: Belongs to the pirin family.

266748:EL218 RS03605
gene id: 266748:EL218_RS03605
uniprot id: A0A448NP33
names: Function
names: Similarity
messages: ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.
messages: Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.

266748:EL218 RS10985
gene id: 266748:EL218_RS10985
uniprot id: A0A448NTA3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L/F-transferase family.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.

266748:EL218 RS08255
gene id: 266748:EL218_RS08255
uniprot id: A0A448NRT5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

266748:EL218 RS02840
gene id: 266748:EL218_RS02840
uniprot id: A0A3S4UZU7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 51 family.
messages: Cell membrane
messages: Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors.

266748:EL218 RS07755
gene id: 266748:EL218_RS07755
uniprot id: A0A448NRM1
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

266748:EL218 RS14270
gene id: 266748:EL218_RS14270
uniprot id: A0A448NV61
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

266748:EL218 RS01440
gene id: 266748:EL218_RS01440
uniprot id: A0A3S4W111
names: Similarity
messages: Belongs to the peptidase C40 family.

266748:EL218 RS05015
gene id: 266748:EL218_RS05015
uniprot id: A0A3S5EUQ2
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

266748:EL218 RS11420
gene id: 266748:EL218_RS11420
uniprot id: A0A3S4W5J6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

266748:EL218 RS10860
gene id: 266748:EL218_RS10860
uniprot id: A0A448NTA4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

266748:EL218 RS07335
gene id: 266748:EL218_RS07335
uniprot id: A0A3S4UYC2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

266748:EL218 RS03260
gene id: 266748:EL218_RS03260
uniprot id: A0A3S4WQ22
names: Similarity
messages: Belongs to the LacAB/RpiB family.

266748:EL218 RS10845
gene id: 266748:EL218_RS10845
uniprot id: A0A448NTB0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

266748:EL218 RS03340
gene id: 266748:EL218_RS03340
uniprot id: A0A3S4V044
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

266748:EL218 RS03345
gene id: 266748:EL218_RS03345
uniprot id: A0A3S4UJW9
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

266748:EL218 RS10345
gene id: 266748:EL218_RS10345
uniprot id: A0A448NT07
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

266748:EL218 RS00235
gene id: 266748:EL218_RS00235
uniprot id: A0A448NM81
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

266748:EL218 RS09555
gene id: 266748:EL218_RS09555
uniprot id: A0A448NSL1
names: Subcellular Location Annotation
messages: Membrane

266748:EL218 RS00150
gene id: 266748:EL218_RS00150
uniprot id: A0A3S5EUC6
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

266748:EL218 RS01305
gene id: 266748:EL218_RS01305
uniprot id: A0A3S4YG89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DcuA/DcuB transporter (TC 2.A.13.1) family.
messages: Cell inner membrane
messages: Membrane

266748:EL218 RS08450
gene id: 266748:EL218_RS08450
uniprot id: A0A3S4V2U8
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

266748:EL218 RS02185
gene id: 266748:EL218_RS02185
uniprot id: A0A448NNH4
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

266748:EL218 RS05050
gene id: 266748:EL218_RS05050
uniprot id: A0A3S4W3S5
names: Similarity
messages: Belongs to the nitroreductase family.

266748:EL218 RS10590
gene id: 266748:EL218_RS10590
uniprot id: A0A448NT63
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

266748:EL218 RS00435
gene id: 266748:EL218_RS00435
uniprot id: A0A448NMC7
names: Similarity
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.

266748:EL218 RS00680
gene id: 266748:EL218_RS00680
uniprot id: A0A3S4W0I5
names: Subcellular Location Annotation
messages: Membrane

266748:EL218 RS02880
gene id: 266748:EL218_RS02880
uniprot id: A0A3S4UQL5
names: Similarity
messages: Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family. Bacterial alpha-2-macroglobulin subfamily.

266748:EL218 RS11150
gene id: 266748:EL218_RS11150
uniprot id: A0A3S4WTS8
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

266748:EL218 RS01430
gene id: 266748:EL218_RS01430
uniprot id: A0A3S4UPP4
names: Subcellular Location Annotation
messages: Membrane

266748:EL218 RS07200
gene id: 266748:EL218_RS07200
uniprot id: A0A3S4WSJ8
names: Subcellular Location Annotation
messages: Membrane

266748:EL218 RS01485
gene id: 266748:EL218_RS01485
uniprot id: A0A448NN32
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

266748:EL218 RS00510
gene id: 266748:EL218_RS00510
uniprot id: A0A3S4UUJ1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

266748:EL218 RS05345
gene id: 266748:EL218_RS05345
uniprot id: A0A3S4USN9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

266748:EL218 RS01505
gene id: 266748:EL218_RS01505
uniprot id: A0A3S5EUF6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

266748:EL218 RS11650
gene id: 266748:EL218_RS11650
uniprot id: A0A3S4VG90
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

266748:EL218 RS01035
gene id: 266748:EL218_RS01035
uniprot id: A0A3S4WNN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

266748:EL218 RS04465
gene id: 266748:EL218_RS04465
uniprot id: A0A448NPK9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

266748:EL218 RS10420
gene id: 266748:EL218_RS10420
uniprot id: A0A3S4UU77
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell inner membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

266748:EL218 RS03365
gene id: 266748:EL218_RS03365
uniprot id: A0A448NP04
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

266748:EL218 RS01285
gene id: 266748:EL218_RS01285
uniprot id: A0A448NMR4
names: Similarity
messages: Belongs to the peptidase M1 family.

266748:EL218 RS12860
gene id: 266748:EL218_RS12860
uniprot id: A0A448NUC9
names: Caution
names: Function
names: Similarity
messages: Belongs to the LpxK family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).

266748:EL218 RS04710
gene id: 266748:EL218_RS04710
uniprot id: A0A448NPP9
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

266748:EL218 RS01330
gene id: 266748:EL218_RS01330
uniprot id: A0A448NMT2
names: Subcellular Location Annotation
messages: Membrane

266748:EL218 RS12100
gene id: 266748:EL218_RS12100
uniprot id: A0A448NU02
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

266748:EL218 RS03235
gene id: 266748:EL218_RS03235
uniprot id: A0A3S4UQT1
names: Similarity
messages: Belongs to the UPF0246 family.

266748:EL218 RS04530
gene id: 266748:EL218_RS04530
uniprot id: A0A448NPS2
names: Similarity
messages: Belongs to the carotenoid/retinoid oxidoreductase family.

266748:EL218 RS05545
gene id: 266748:EL218_RS05545
uniprot id: A0A3S4YJC3
names: Subcellular Location Annotation
messages: Membrane

266748:EL218 RS03510
gene id: 266748:EL218_RS03510
uniprot id: A0A3S4UQZ3
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

266748:EL218 RS00735
gene id: 266748:EL218_RS00735
uniprot id: A0A448NMP7
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

266748:EL218 RS05080
gene id: 266748:EL218_RS05080
uniprot id: A0A3S4VE89
names: Function
names: Similarity
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

266748:EL218 RS13965
gene id: 266748:EL218_RS13965
uniprot id: A0A448NUZ3
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

266748:EL218 RS05405
gene id: 266748:EL218_RS05405
uniprot id: A0A448NQ80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

266748:EL218 RS05270
gene id: 266748:EL218_RS05270
uniprot id: A0A448NQ09
names: Subcellular Location Annotation
messages: Membrane

266748:EL218 RS10565
gene id: 266748:EL218_RS10565
uniprot id: A0A448NT20
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

266748:EL218 RS03545
gene id: 266748:EL218_RS03545
uniprot id: A0A448NP89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

266748:EL218 RS01585
gene id: 266748:EL218_RS01585
uniprot id: A0A448NN57
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

266748:EL218 RS05700
gene id: 266748:EL218_RS05700
uniprot id: A0A3S4ULS5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAK/KUP transporter (TC 2.A.72) family.
messages: Cell membrane
messages: Membrane
messages: Transport of potassium into the cell.

266748:EL218 RS09670
gene id: 266748:EL218_RS09670
uniprot id: A0A3S4YTT5
names: Subcellular Location Annotation
messages: Membrane

266748:EL218 RS01385
gene id: 266748:EL218_RS01385
uniprot id: A0A3S4UYY9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

266748:EL218 RS01935
gene id: 266748:EL218_RS01935
uniprot id: A0A3S4UZA1
names: Subcellular Location Annotation
messages: Membrane

266748:EL218 RS04595
gene id: 266748:EL218_RS04595
uniprot id: A0A448NPM0
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

266748:EL218 RS02190
gene id: 266748:EL218_RS02190
uniprot id: A0A3S4UZG0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

266748:EL218 RS14210
gene id: 266748:EL218_RS14210
uniprot id: A0A3S4V0G4
names: Similarity
messages: Belongs to the HSP15 family.

266748:EL218 RS02780
gene id: 266748:EL218_RS02780
uniprot id: A0A3S4W1R9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

266748:EL218 RS13215
gene id: 266748:EL218_RS13215
uniprot id: A0A3S4V4G3
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

266748:EL218 RS11000
gene id: 266748:EL218_RS11000
uniprot id: A0A448NTE8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

266748:EL218 RS00900
gene id: 266748:EL218_RS00900
uniprot id: A0A448NMK3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

266748:EL218 RS10745
gene id: 266748:EL218_RS10745
uniprot id: A0A3S4UZD1
names: Similarity
messages: Belongs to the SufE family.

266748:EL218 RS01015
gene id: 266748:EL218_RS01015
uniprot id: A0A3S5EUE4
names: Similarity
messages: Belongs to the DEAD box helicase family.

266748:EL218 RS04100
gene id: 266748:EL218_RS04100
uniprot id: A0A3S4YHZ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
messages: Belongs to the KdsB family.
messages: Cytoplasm

266748:EL218 RS00100
gene id: 266748:EL218_RS00100
uniprot id: A0A3S4UHV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

266748:EL218 RS10465
gene id: 266748:EL218_RS10465
uniprot id: A0A3S4VFV6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

266748:EL218 RS04475
gene id: 266748:EL218_RS04475
uniprot id: A0A448NPR2
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

266748:EL218 RS03760
gene id: 266748:EL218_RS03760
uniprot id: A0A448NP74
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic Ku family.
messages: Homodimer. Interacts with LigD.
messages: With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD.

266748:EL218 RS01475
gene id: 266748:EL218_RS01475
uniprot id: A0A448NMW2
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Feedback inhibited by histidine.

266748:EL218 RS08595
gene id: 266748:EL218_RS08595
uniprot id: A0A3S4UYP6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

266748:EL218 RS02430
gene id: 266748:EL218_RS02430
uniprot id: A0A3S4VC80
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

266748:EL218 RS06320
gene id: 266748:EL218_RS06320
uniprot id: A0A448NQM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

266748:EL218 RS10390
gene id: 266748:EL218_RS10390
uniprot id: A0A3S5EUW0
names: Function
names: Similarity
messages: Belongs to the SELO family.
messages: Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).

266748:EL218 RS00635
gene id: 266748:EL218_RS00635
uniprot id: A0A3S4VB59
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

266748:EL218 RS05975
gene id: 266748:EL218_RS05975
uniprot id: A0A448NQK0
names: Cofactor
names: Function
names: Similarity
messages: Adenine glycosylase active on G-A mispairs.
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.

266748:EL218 RS12925
gene id: 266748:EL218_RS12925
uniprot id: A0A3S4UV58
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

266748:EL218 RS07210
gene id: 266748:EL218_RS07210
uniprot id: A0A448NR31
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

266748:EL218 RS06430
gene id: 266748:EL218_RS06430
uniprot id: A0A3S4ULZ2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

266748:EL218 RS02010
gene id: 266748:EL218_RS02010
uniprot id: A0A448NN77
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

266748:EL218 RS12620
gene id: 266748:EL218_RS12620
uniprot id: A0A3S4W5Z7
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

266748:EL218 RS02935
gene id: 266748:EL218_RS02935
uniprot id: A0A448NNP5
names: Similarity
messages: Belongs to the AHA1 family.

266748:EL218 RS12205
gene id: 266748:EL218_RS12205
uniprot id: A0A3S4UUV4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0382 family.
messages: Membrane

266748:EL218 RS03960
gene id: 266748:EL218_RS03960
uniprot id: A0A3S4V0J3
names: Similarity
messages: Belongs to the UPF0758 family.

266748:EL218 RS06210
gene id: 266748:EL218_RS06210
uniprot id: A0A448NQR8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0394 family.
messages: Membrane

266748:EL218 RS09910
gene id: 266748:EL218_RS09910
uniprot id: A0A448NSQ6
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

266748:EL218 RS07290
gene id: 266748:EL218_RS07290
uniprot id: A0A3S4UM74
names: Subcellular Location Annotation
messages: Membrane

266748:EL218 RS10865
gene id: 266748:EL218_RS10865
uniprot id: A0A448NT94
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

266748:EL218 RS02790
gene id: 266748:EL218_RS02790
uniprot id: A0A3S4WPT2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
messages: Consists of three domains: the N-terminal catalytic domain, the anticodon-binding domain and the C-terminal extension.
messages: Cytoplasm
messages: Homodimer.

266748:EL218 RS05400
gene id: 266748:EL218_RS05400
uniprot id: A0A448NQB7
names: Subcellular Location Annotation
messages: Membrane

266748:EL218 RS12425
gene id: 266748:EL218_RS12425
uniprot id: A0A3S5EUY3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

266748:EL218 RS12810
gene id: 266748:EL218_RS12810
uniprot id: A0A3S5EUY8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

266748:EL218 RS02845
gene id: 266748:EL218_RS02845
uniprot id: A0A3S4WPU2
names: Subcellular Location Annotation
messages: Membrane

266748:EL218 RS07400
gene id: 266748:EL218_RS07400
uniprot id: A0A448NRB1
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

266748:EL218 RS04120
gene id: 266748:EL218_RS04120
uniprot id: A0A3S4W2K9
names: Similarity
messages: Belongs to the phosphohexose mutase family.

266748:EL218 RS00040
gene id: 266748:EL218_RS00040
uniprot id: A0A3S4UNR4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

266748:EL218 RS12410
gene id: 266748:EL218_RS12410
uniprot id: A0A3S4UNP5
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

266748:EL218 RS12690
gene id: 266748:EL218_RS12690
uniprot id: A0A3S4V499
names: Similarity
messages: Belongs to the SCO1/2 family.

266748:EL218 RS00915
gene id: 266748:EL218_RS00915
uniprot id: A0A448NMJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. TCR/Tet family.
messages: Membrane

266748:EL218 RS04435
gene id: 266748:EL218_RS04435
uniprot id: A0A3S4YRI1
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

266748:EL218 RS02475
gene id: 266748:EL218_RS02475
uniprot id: A0A448NNI2
names: Function
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family.
messages: Specifically catalyzes the dephosphorylation of 2-phosphoglycolate.

266748:EL218 RS01865
gene id: 266748:EL218_RS01865
uniprot id: A0A448NN64
names: Similarity
messages: Belongs to the UDP-galactopyranose/dTDP-fucopyranose mutase family.

266748:EL218 RS07285
gene id: 266748:EL218_RS07285
uniprot id: A0A3S4WSK8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

266748:EL218 RS03910
gene id: 266748:EL218_RS03910
uniprot id: A0A3S4W2G7
names: Function
names: Similarity
names: Subunit
messages: Catalyzes the ATP-dependent polymerization of arginine and aspartate to multi-L-arginyl-poly-L-aspartic acid (cyanophycin; a water-insoluble reserve polymer).
messages: Homodimer.
messages: In the C-terminal section; belongs to the MurCDEF family.

266748:EL218 RS04075
gene id: 266748:EL218_RS04075
uniprot id: A0A3S4UKC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Membrane

266748:EL218 RS04240
gene id: 266748:EL218_RS04240
uniprot id: A0A3S4W2N6
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

266748:EL218 RS03525
gene id: 266748:EL218_RS03525
uniprot id: A0A3S4WQ80
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenine deaminase type 2 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism.

266748:EL218 RS14070
gene id: 266748:EL218_RS14070
uniprot id: A0A448NV26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ribonuclease N1/T1 family.
messages: Secreted

266748:EL218 RS01970
gene id: 266748:EL218_RS01970
uniprot id: A0A3S4YGN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

266748:EL218 RS12295
gene id: 266748:EL218_RS12295
uniprot id: A0A3S4V443
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

266748:EL218 RS02690
gene id: 266748:EL218_RS02690
uniprot id: A0A3S5EUI3
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

266748:EL218 RS09630
gene id: 266748:EL218_RS09630
uniprot id: A0A3S4WTB3
names: Similarity
messages: Belongs to the AHA1 family.

266748:EL218 RS09220
gene id: 266748:EL218_RS09220
uniprot id: A0A3S4VFH2
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

266748:EL218 RS03730
gene id: 266748:EL218_RS03730
uniprot id: A0A3S4YHQ8
names: Cofactor
names: Similarity
messages: Belongs to the fatty acid desaturase type 2 family.
messages: Binds 2 iron ions per subunit.

266748:EL218 RS03625
gene id: 266748:EL218_RS03625
uniprot id: A0A448NP78
names: Similarity
messages: Belongs to the peptidase M17 family.

266748:EL218 RS02530
gene id: 266748:EL218_RS02530
uniprot id: A0A448NNI4
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

266748:EL218 RS09295
gene id: 266748:EL218_RS09295
uniprot id: A0A3S4WT66
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

266748:EL218 RS05830
gene id: 266748:EL218_RS05830
uniprot id: A0A3S4USU0
names: Cofactor
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.

266748:EL218 RS05840
gene id: 266748:EL218_RS05840
uniprot id: A0A3S4W402
names: Similarity
messages: Belongs to the malate synthase family.

266748:EL218 RS08590
gene id: 266748:EL218_RS08590
uniprot id: A0A3S5EUU1
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

266748:EL218 RS05150
gene id: 266748:EL218_RS05150
uniprot id: A0A448NQ61
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

266748:EL218 RS03475
gene id: 266748:EL218_RS03475
uniprot id: A0A3S4UQY2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

266748:EL218 RS06980
gene id: 266748:EL218_RS06980
uniprot id: A0A448NR23
names: Similarity
messages: Belongs to the homogentisate dioxygenase family.

266748:EL218 RS02885
gene id: 266748:EL218_RS02885
uniprot id: A0A448NNN2
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

266748:EL218 RS01635
gene id: 266748:EL218_RS01635
uniprot id: A0A3S4UV88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

266748:EL218 RS11835
gene id: 266748:EL218_RS11835
uniprot id: A0A448NTU2
names: Similarity
messages: Belongs to the NusB family.

266748:EL218 RS13390
gene id: 266748:EL218_RS13390
uniprot id: A0A448NUN8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

266748:EL218 RS09745
gene id: 266748:EL218_RS09745
uniprot id: A0A448NSN4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TPP enzyme family. MenD subfamily.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
messages: Homodimer.

266748:EL218 RS08310
gene id: 266748:EL218_RS08310
uniprot id: A0A448NRU5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

266748:EL218 RS10785
gene id: 266748:EL218_RS10785
uniprot id: A0A448NTA5
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

266748:EL218 RS05480
gene id: 266748:EL218_RS05480
uniprot id: A0A448NQB5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

266748:EL218 RS14190
gene id: 266748:EL218_RS14190
uniprot id: A0A3S4VH59
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

266748:EL218 RS08545
gene id: 266748:EL218_RS08545
uniprot id: A0A3S4YK86
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

266748:EL218 RS03075
gene id: 266748:EL218_RS03075
uniprot id: A0A3S4YQP3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

266748:EL218 RS01450
gene id: 266748:EL218_RS01450
uniprot id: A0A448NMW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 87 family.
messages: Membrane

266748:EL218 RS00610
gene id: 266748:EL218_RS00610
uniprot id: A0A3S5EUD6
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

266748:EL218 RS03230
gene id: 266748:EL218_RS03230
uniprot id: A0A448NNV5
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

266748:EL218 RS04395
gene id: 266748:EL218_RS04395
uniprot id: A0A3S5EUL9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

266748:EL218 RS10075
gene id: 266748:EL218_RS10075
uniprot id: A0A448NSS8
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

266748:EL218 RS04645
gene id: 266748:EL218_RS04645
uniprot id: A0A3S4WRP5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

266748:EL218 RS10065
gene id: 266748:EL218_RS10065
uniprot id: A0A448NSS2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

266748:EL218 RS12450
gene id: 266748:EL218_RS12450
uniprot id: A0A3S4YLJ0
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

266748:EL218 RS07980
gene id: 266748:EL218_RS07980
uniprot id: A0A3S4UME5
names: Subcellular Location Annotation
messages: Membrane

266748:EL218 RS07930
gene id: 266748:EL218_RS07930
uniprot id: A0A448NRL6
names: Subcellular Location Annotation
messages: Membrane

266748:EL218 RS12330
gene id: 266748:EL218_RS12330
uniprot id: A0A448NU56
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

266748:EL218 RS00620
gene id: 266748:EL218_RS00620
uniprot id: A0A448NMD9
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

266748:EL218 RS07190
gene id: 266748:EL218_RS07190
uniprot id: A0A3S4W4C1
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.

266748:EL218 RS12355
gene id: 266748:EL218_RS12355
uniprot id: A0A3S4UUX5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

266748:EL218 RS02390
gene id: 266748:EL218_RS02390
uniprot id: A0A448NNL6
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

266748:EL218 RS05870
gene id: 266748:EL218_RS05870
uniprot id: A0A3S4WS66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

266748:EL218 RS04165
gene id: 266748:EL218_RS04165
uniprot id: A0A448NPF1
names: Subcellular Location Annotation
messages: Membrane

266748:EL218 RS09300
gene id: 266748:EL218_RS09300
uniprot id: A0A3S4UMR0
names: Similarity
messages: Belongs to the nitroreductase family.

266748:EL218 RS07380
gene id: 266748:EL218_RS07380
uniprot id: A0A3S4VEX4
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

266748:EL218 RS13025
gene id: 266748:EL218_RS13025
uniprot id: A0A448NUG2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

266748:EL218 RS03695
gene id: 266748:EL218_RS03695
uniprot id: A0A3S4V0C6
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

266748:EL218 RS09235
gene id: 266748:EL218_RS09235
uniprot id: A0A3S5EUU7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

266748:EL218 RS04215
gene id: 266748:EL218_RS04215
uniprot id: A0A3S4YRD6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Membrane

266748:EL218 RS00730
gene id: 266748:EL218_RS00730
uniprot id: A0A448NMF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

266748:EL218 RS11730
gene id: 266748:EL218_RS11730
uniprot id: A0A448NTR9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

266748:EL218 RS02085
gene id: 266748:EL218_RS02085
uniprot id: A0A448NN88
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the DNA photolyase class-1 family.
messages: Binds 1 5,10-methenyltetrahydrofolate (MTHF) per subunit.
messages: Binds 1 FAD per subunit.
messages: May have a photoreceptor function.

266748:EL218 RS05320
gene id: 266748:EL218_RS05320
uniprot id: A0A448NQ30
names: Similarity
messages: Belongs to the IMPACT family.

266748:EL218 RS11055
gene id: 266748:EL218_RS11055
uniprot id: A0A448NTL9
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

266748:EL218 RS10325
gene id: 266748:EL218_RS10325
uniprot id: A0A448NSY6
names: Similarity
messages: Belongs to the glutamine synthetase family.

266748:EL218 RS04900
gene id: 266748:EL218_RS04900
uniprot id: A0A448NPX7
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

266748:EL218 RS08410
gene id: 266748:EL218_RS08410
uniprot id: A0A3S5EUT9
names: Subcellular Location Annotation
messages: Membrane

266748:EL218 RS08930
gene id: 266748:EL218_RS08930
uniprot id: A0A3S4UMM6
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

266748:EL218 RS11660
gene id: 266748:EL218_RS11660
uniprot id: A0A3S4YUF1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

266748:EL218 RS08515
gene id: 266748:EL218_RS08515
uniprot id: A0A448NS58
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

266748:EL218 RS14150
gene id: 266748:EL218_RS14150
uniprot id: A0A448NV22
names: Subcellular Location Annotation
messages: Membrane

266748:EL218 RS04720
gene id: 266748:EL218_RS04720
uniprot id: A0A448NPQ4
names: Subcellular Location Annotation
messages: Membrane

266748:EL218 RS05410
gene id: 266748:EL218_RS05410
uniprot id: A0A448NQ40
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

266748:EL218 RS01375
gene id: 266748:EL218_RS01375
uniprot id: A0A3S5EUF3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

266748:EL218 RS10870
gene id: 266748:EL218_RS10870
uniprot id: A0A3S4W5E4
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

266748:EL218 RS08165
gene id: 266748:EL218_RS08165
uniprot id: A0A3S4V2S0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

266748:EL218 RS12785
gene id: 266748:EL218_RS12785
uniprot id: A0A3S4UNT8
names: Subcellular Location Annotation
messages: Membrane

266748:EL218 RS10835
gene id: 266748:EL218_RS10835
uniprot id: A0A448NTB7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell membrane
messages: Self-interacts. Interacts with FtsZ.

266748:EL218 RS01555
gene id: 266748:EL218_RS01555
uniprot id: A0A448NN16
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

266748:EL218 RS12465
gene id: 266748:EL218_RS12465
uniprot id: A0A3S4W5X4
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

266748:EL218 RS13125
gene id: 266748:EL218_RS13125
uniprot id: A0A448NUI4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

266748:EL218 RS01390
gene id: 266748:EL218_RS01390
uniprot id: A0A448NMY0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

266748:EL218 RS07985
gene id: 266748:EL218_RS07985
uniprot id: A0A448NRM6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

266748:EL218 RS01320
gene id: 266748:EL218_RS01320
uniprot id: A0A3S4UIM6
names: Similarity
messages: Belongs to the class-II fumarase/aspartase family. Aspartase subfamily.

266748:EL218 RS04605
gene id: 266748:EL218_RS04605
uniprot id: A0A448NPR3
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

266748:EL218 RS02925
gene id: 266748:EL218_RS02925
uniprot id: A0A448NNS8
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

266748:EL218 RS08720
gene id: 266748:EL218_RS08720
uniprot id: A0A3S4W4S7
names: Similarity
messages: Belongs to the YoeB family.

266748:EL218 RS01925
gene id: 266748:EL218_RS01925
uniprot id: A0A3S4YGM2
names: Similarity
messages: Belongs to the iron-containing alcohol dehydrogenase family.

266748:EL218 RS06825
gene id: 266748:EL218_RS06825
uniprot id: A0A3S4UT43
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

266748:EL218 RS03255
gene id: 266748:EL218_RS03255
uniprot id: A0A448NNX7
names: Similarity
messages: Belongs to the transketolase family.

266748:EL218 RS08090
gene id: 266748:EL218_RS08090
uniprot id: A0A448NRQ4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

266748:EL218 RS05425
gene id: 266748:EL218_RS05425
uniprot id: A0A3S5EUQ7
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

266748:EL218 RS14235
gene id: 266748:EL218_RS14235
uniprot id: A0A3S4UVL6
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

266748:EL218 RS12795
gene id: 266748:EL218_RS12795
uniprot id: A0A3S4YUU0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvB family.
messages: Forms a complex with RuvA.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.

266748:EL218 RS03360
gene id: 266748:EL218_RS03360
uniprot id: A0A3S4UW72
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

266748:EL218 RS04280
gene id: 266748:EL218_RS04280
uniprot id: A0A448NPH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

266748:EL218 RS10490
gene id: 266748:EL218_RS10490
uniprot id: A0A448NT39
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Homotetramer.

266748:EL218 RS08140
gene id: 266748:EL218_RS08140
uniprot id: A0A3S4UYK0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

266748:EL218 RS12445
gene id: 266748:EL218_RS12445
uniprot id: A0A448NUD8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

266748:EL218 RS08275
gene id: 266748:EL218_RS08275
uniprot id: A0A3S4UMH2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

266748:EL218 RS00990
gene id: 266748:EL218_RS00990
uniprot id: A0A3S4UYL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane

266748:EL218 RS05720
gene id: 266748:EL218_RS05720
uniprot id: A0A3S5EUR0
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

266748:EL218 RS11985
gene id: 266748:EL218_RS11985
uniprot id: A0A448NTV1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

266748:EL218 RS14065
gene id: 266748:EL218_RS14065
uniprot id: A0A448NV15
names: Similarity
messages: Belongs to the NAD synthetase family.

266748:EL218 RS01230
gene id: 266748:EL218_RS01230
uniprot id: A0A3S4WNU8
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

266748:EL218 RS00480
gene id: 266748:EL218_RS00480
uniprot id: A0A3S4YFQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

266748:EL218 RS12125
gene id: 266748:EL218_RS12125
uniprot id: A0A3S4UZT1
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

266748:EL218 RS12545
gene id: 266748:EL218_RS12545
uniprot id: A0A3S4V476
names: Function
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

266748:EL218 RS05225
gene id: 266748:EL218_RS05225
uniprot id: A0A448NQ07
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

266748:EL218 RS05735
gene id: 266748:EL218_RS05735
uniprot id: A0A3S4USS8
names: Similarity
messages: Belongs to the universal stress protein A family.

266748:EL218 RS05695
gene id: 266748:EL218_RS05695
uniprot id: A0A448NQI1
names: Similarity
messages: Belongs to the Fur family.

266748:EL218 RS10320
gene id: 266748:EL218_RS10320
uniprot id: A0A448NSX1
names: Similarity
messages: Belongs to the peptidase C40 family.

266748:EL218 RS12195
gene id: 266748:EL218_RS12195
uniprot id: A0A448NU25
names: Similarity
messages: Belongs to the HMG-CoA reductase family.

266748:EL218 RS02855
gene id: 266748:EL218_RS02855
uniprot id: A0A3S4VCF7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

266748:EL218 RS14110
gene id: 266748:EL218_RS14110
uniprot id: A0A3S4YM14
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

266748:EL218 RS10690
gene id: 266748:EL218_RS10690
uniprot id: A0A3S4YKY3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

266748:EL218 RS13595
gene id: 266748:EL218_RS13595
uniprot id: A0A3S4UVF0
names: Similarity
messages: Belongs to the aspartokinase family.

266748:EL218 RS04715
gene id: 266748:EL218_RS04715
uniprot id: A0A3S4USD5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

266748:EL218 RS02980
gene id: 266748:EL218_RS02980
uniprot id: A0A3S4YQM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

266748:EL218 RS09070
gene id: 266748:EL218_RS09070
uniprot id: A0A448NS98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

266748:EL218 RS13305
gene id: 266748:EL218_RS13305
uniprot id: A0A448NUR1
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

266748:EL218 RS05910
gene id: 266748:EL218_RS05910
uniprot id: A0A448NQH3
names: Similarity
messages: Belongs to the cytochrome P450 family.

266748:EL218 RS12285
gene id: 266748:EL218_RS12285
uniprot id: A0A448NU71
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

266748:EL218 RS07850
gene id: 266748:EL218_RS07850
uniprot id: A0A3S4YK19
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

266748:EL218 RS08095
gene id: 266748:EL218_RS08095
uniprot id: A0A448NRQ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

266748:EL218 RS04210
gene id: 266748:EL218_RS04210
uniprot id: A0A3S4UKF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Membrane

266748:EL218 RS11405
gene id: 266748:EL218_RS11405
uniprot id: A0A448NTT0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

266748:EL218 RS06830
gene id: 266748:EL218_RS06830
uniprot id: A0A3S4YJQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase Y family.
messages: Cell membrane
messages: Endoribonuclease that initiates mRNA decay.

266748:EL218 RS07065
gene id: 266748:EL218_RS07065
uniprot id: A0A3S4V2E5
names: Similarity
messages: Belongs to the peptidase M13 family.

266748:EL218 RS11850
gene id: 266748:EL218_RS11850
uniprot id: A0A3S5EUX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAE transporter (TC 2.A.81) family.
messages: Cell membrane
messages: Membrane

266748:EL218 RS04270
gene id: 266748:EL218_RS04270
uniprot id: A0A448NPI3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

266748:EL218 RS04660
gene id: 266748:EL218_RS04660
uniprot id: A0A448NPN7
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

266748:EL218 RS07385
gene id: 266748:EL218_RS07385
uniprot id: A0A3S4YT51
names: Function
names: Similarity
messages: Belongs to the RlpA family.
messages: Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.

266748:EL218 RS06325
gene id: 266748:EL218_RS06325
uniprot id: A0A3S4VEL9
names: Similarity
messages: Belongs to the HicA mRNA interferase family.

266748:EL218 RS08560
gene id: 266748:EL218_RS08560
uniprot id: A0A3S4WSY5
names: Subcellular Location Annotation
messages: Membrane

266748:EL218 RS04320
gene id: 266748:EL218_RS04320
uniprot id: A0A3S4URH8
names: Similarity
messages: Belongs to the bacterial glucokinase family.

266748:EL218 RS12110
gene id: 266748:EL218_RS12110
uniprot id: A0A3S5EUX9
names: Similarity
messages: Belongs to the pyruvate kinase family.

266748:EL218 RS03440
gene id: 266748:EL218_RS03440
uniprot id: A0A3S4W248
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

266748:EL218 RS11370
gene id: 266748:EL218_RS11370
uniprot id: A0A448NTH9
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

266748:EL218 RS04490
gene id: 266748:EL218_RS04490
uniprot id: A0A3S4VDB1
names: Similarity
messages: Belongs to the DNA photolyase family.

266748:EL218 RS07860
gene id: 266748:EL218_RS07860
uniprot id: A0A448NRL5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell membrane
messages: Membrane

266748:EL218 RS06390
gene id: 266748:EL218_RS06390
uniprot id: A0A448NQP7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

266748:EL218 RS12955
gene id: 266748:EL218_RS12955
uniprot id: A0A448NUI7
names: Similarity
messages: Belongs to the peptidase S49 family.

266748:EL218 RS09890
gene id: 266748:EL218_RS09890
uniprot id: A0A3S4W538
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

266748:EL218 RS04155
gene id: 266748:EL218_RS04155
uniprot id: A0A3S4URE1
names: Caution
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
messages: Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

266748:EL218 RS10510
gene id: 266748:EL218_RS10510
uniprot id: A0A448NT25
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

266748:EL218 RS07725
gene id: 266748:EL218_RS07725
uniprot id: A0A3S4WSQ4
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

266748:EL218 RS13590
gene id: 266748:EL218_RS13590
uniprot id: A0A3S4V0B2
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FBPase class 1 family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

266748:EL218 RS05355
gene id: 266748:EL218_RS05355
uniprot id: A0A448NQ68
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

266748:EL218 RS11210
gene id: 266748:EL218_RS11210
uniprot id: A0A448NTG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

266748:EL218 RS00540
gene id: 266748:EL218_RS00540
uniprot id: A0A3S4UYA5
names: Similarity
messages: Belongs to the class-II fumarase/aspartase family. Aspartase subfamily.

266748:EL218 RS05775
gene id: 266748:EL218_RS05775
uniprot id: A0A3S4ULT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

266748:EL218 RS02220
gene id: 266748:EL218_RS02220
uniprot id: A0A448NNC9
names: Similarity
messages: Belongs to the peptidase M24B family.

266748:EL218 RS01400
gene id: 266748:EL218_RS01400
uniprot id: A0A3S4VBN3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

266748:EL218 RS12035
gene id: 266748:EL218_RS12035
uniprot id: A0A3S4YUJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

266748:EL218 RS13940
gene id: 266748:EL218_RS13940
uniprot id: A0A448NV67
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

266748:EL218 RS11570
gene id: 266748:EL218_RS11570
uniprot id: A0A448NTM1
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

266748:EL218 RS08640
gene id: 266748:EL218_RS08640
uniprot id: A0A448NS13
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

266748:EL218 RS13385
gene id: 266748:EL218_RS13385
uniprot id: A0A3S4YLU5
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

266748:EL218 RS12345
gene id: 266748:EL218_RS12345
uniprot id: A0A448NU53
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

266748:EL218 RS11090
gene id: 266748:EL218_RS11090
uniprot id: A0A448NTD6
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

266748:EL218 RS08305
gene id: 266748:EL218_RS08305
uniprot id: A0A3S4UTK8
names: Similarity
messages: Belongs to the EPSP synthase family.

266748:EL218 RS02825
gene id: 266748:EL218_RS02825
uniprot id: A0A448NNP7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

266748:EL218 RS01080
gene id: 266748:EL218_RS01080
uniprot id: A0A448NMQ8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

266748:EL218 RS14260
gene id: 266748:EL218_RS14260
uniprot id: A0A3S4W6H2
names: Similarity
messages: Belongs to the IPP isomerase type 1 family.

266748:EL218 RS04150
gene id: 266748:EL218_RS04150
uniprot id: A0A448NPH4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MenA family. Type 1 subfamily.
messages: Cell membrane
messages: Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK).
messages: Membrane

266748:EL218 RS08735
gene id: 266748:EL218_RS08735
uniprot id: A0A448NS24
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

266748:EL218 RS05185
gene id: 266748:EL218_RS05185
uniprot id: A0A3S4W3U5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system and for the release of the potassium ions to the cytoplasm.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

266748:EL218 RS09495
gene id: 266748:EL218_RS09495
uniprot id: A0A448NSG2
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

266748:EL218 RS13350
gene id: 266748:EL218_RS13350
uniprot id: A0A448NUT2
names: Similarity
messages: Belongs to the ACC deaminase/D-cysteine desulfhydrase family.

266748:EL218 RS09060
gene id: 266748:EL218_RS09060
uniprot id: A0A448NSF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

266748:EL218 RS00330
gene id: 266748:EL218_RS00330
uniprot id: A0A448NMH9
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

266748:EL218 RS13860
gene id: 266748:EL218_RS13860
uniprot id: A0A448NUY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Membrane

266748:EL218 RS00700
gene id: 266748:EL218_RS00700
uniprot id: A0A3S4YPB3
names: Subcellular Location Annotation
messages: Membrane

266748:EL218 RS12095
gene id: 266748:EL218_RS12095
uniprot id: A0A3S4YUK6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

266748:EL218 RS02095
gene id: 266748:EL218_RS02095
uniprot id: A0A3S4UVG6
names: Similarity
names: Subunit
messages: Belongs to the aldehyde dehydrogenase family.
messages: Homotetramer.

266748:EL218 RS12470
gene id: 266748:EL218_RS12470
uniprot id: A0A3S4V462
names: Similarity
messages: Belongs to the citrate synthase family.

266748:EL218 RS10830
gene id: 266748:EL218_RS10830
uniprot id: A0A448NTA8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

266748:EL218 RS08335
gene id: 266748:EL218_RS08335
uniprot id: A0A448NRT6
names: Domain
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
messages: Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.

266748:EL218 RS08245
gene id: 266748:EL218_RS08245
uniprot id: A0A448NRT3
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

266748:EL218 RS12220
gene id: 266748:EL218_RS12220
uniprot id: A0A3S4V436
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

266748:EL218 RS03915
gene id: 266748:EL218_RS03915
uniprot id: A0A448NPB4
names: Function
names: Similarity
messages: Belongs to the peptidase S51 family.
messages: Exopeptidase that catalyzes the hydrolytic cleavage of multi-L-arginyl-poly-L-aspartic acid (cyanophycin; a water-insoluble reserve polymer) into aspartate-arginine dipeptides.

266748:EL218 RS03725
gene id: 266748:EL218_RS03725
uniprot id: A0A448NP96
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

266748:EL218 RS03815
gene id: 266748:EL218_RS03815
uniprot id: A0A3S4UR66
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

266748:EL218 RS04985
gene id: 266748:EL218_RS04985
uniprot id: A0A3S4V1V4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

266748:EL218 RS00160
gene id: 266748:EL218_RS00160
uniprot id: A0A3S4UUA3
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

266748:EL218 RS12155
gene id: 266748:EL218_RS12155
uniprot id: A0A3S4W5T3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

266748:EL218 RS04565
gene id: 266748:EL218_RS04565
uniprot id: A0A448NPP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

266748:EL218 RS06440
gene id: 266748:EL218_RS06440
uniprot id: A0A448NQQ7
names: Subcellular Location Annotation
messages: Membrane

266748:EL218 RS11330
gene id: 266748:EL218_RS11330
uniprot id: A0A448NTJ3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M20B family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Cleaves the N-terminal amino acid of tripeptides.
messages: Cytoplasm

266748:EL218 RS01335
gene id: 266748:EL218_RS01335
uniprot id: A0A3S4UV26
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HemJ family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Catalyzes the oxidation of protoporphyrinogen IX to protoporphyrin IX.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

266748:EL218 RS06620
gene id: 266748:EL218_RS06620
uniprot id: A0A448NQT7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

266748:EL218 RS01195
gene id: 266748:EL218_RS01195
uniprot id: A0A448NMT5
names: Subcellular Location Annotation
messages: Membrane

266748:EL218 RS10615
gene id: 266748:EL218_RS10615
uniprot id: A0A3S4W5B5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

266748:EL218 RS02950
gene id: 266748:EL218_RS02950
uniprot id: A0A3S4W1V5
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

266748:EL218 RS01510
gene id: 266748:EL218_RS01510
uniprot id: A0A3S4UV63
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the PRA-PH family.
messages: In the N-terminal section; belongs to the PRA-CH family.

266748:EL218 RS12280
gene id: 266748:EL218_RS12280
uniprot id: A0A448NU45
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

266748:EL218 RS09225
gene id: 266748:EL218_RS09225
uniprot id: A0A448NSB3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

266748:EL218 RS05130
gene id: 266748:EL218_RS05130
uniprot id: A0A448NQ49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0073 (Hly-III) family.
messages: Membrane

266748:EL218 RS01735
gene id: 266748:EL218_RS01735
uniprot id: A0A448NN49
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Homodimer.

266748:EL218 RS05385
gene id: 266748:EL218_RS05385
uniprot id: A0A3S4WS19
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

266748:EL218 RS04665
gene id: 266748:EL218_RS04665
uniprot id: A0A448NPS1
names: Similarity
messages: Belongs to the ArsC family.

266748:EL218 RS04055
gene id: 266748:EL218_RS04055
uniprot id: A0A448NPE4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urocanase family.
messages: Binds 1 NAD(+) per subunit.
messages: Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

266748:EL218 RS12935
gene id: 266748:EL218_RS12935
uniprot id: A0A448NUJ3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

266748:EL218 RS02450
gene id: 266748:EL218_RS02450
uniprot id: A0A448NNG0
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

266748:EL218 RS10530
gene id: 266748:EL218_RS10530
uniprot id: A0A3S4WTL9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

266748:EL218 RS01135
gene id: 266748:EL218_RS01135
uniprot id: A0A3S4UYT0
names: Similarity
messages: Belongs to the thioredoxin family.

266748:EL218 RS04375
gene id: 266748:EL218_RS04375
uniprot id: A0A448NPP0
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

266748:EL218 RS06445
gene id: 266748:EL218_RS06445
uniprot id: A0A3S4VEM9
names: Subcellular Location Annotation
messages: Cytoplasm

266748:EL218 RS09050
gene id: 266748:EL218_RS09050
uniprot id: A0A3S4YKD6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

266748:EL218 RS10540
gene id: 266748:EL218_RS10540
uniprot id: A0A3S4VFX1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

266748:EL218 RS13085
gene id: 266748:EL218_RS13085
uniprot id: A0A3S4V051
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

266748:EL218 RS07250
gene id: 266748:EL218_RS07250
uniprot id: A0A448NR78
names: Similarity
messages: Belongs to the sigma-54 factor family.

266748:EL218 RS01380
gene id: 266748:EL218_RS01380
uniprot id: A0A448NMT1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

266748:EL218 RS11805
gene id: 266748:EL218_RS11805
uniprot id: A0A448NTV3
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

266748:EL218 RS07315
gene id: 266748:EL218_RS07315
uniprot id: A0A448NRG6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

266748:EL218 RS05450
gene id: 266748:EL218_RS05450
uniprot id: A0A448NQC9
names: Subcellular Location Annotation
messages: Membrane

266748:EL218 RS01220
gene id: 266748:EL218_RS01220
uniprot id: A0A3S4UYU9
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

266748:EL218 RS08905
gene id: 266748:EL218_RS08905
uniprot id: A0A448NS63
names: Similarity
messages: Belongs to the peptidase C40 family.

266748:EL218 RS00085
gene id: 266748:EL218_RS00085
uniprot id: A0A3S4YFE0
names: Subcellular Location Annotation
messages: Membrane

266748:EL218 RS05040
gene id: 266748:EL218_RS05040
uniprot id: A0A3S4YJ80
names: Similarity
messages: Belongs to the OsmC/Ohr family.

266748:EL218 RS11575
gene id: 266748:EL218_RS11575
uniprot id: A0A3S5EUX2
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

266748:EL218 RS02105
gene id: 266748:EL218_RS02105
uniprot id: A0A3S4YGR3
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

266748:EL218 RS06985
gene id: 266748:EL218_RS06985
uniprot id: A0A448NR39
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

266748:EL218 RS08870
gene id: 266748:EL218_RS08870
uniprot id: A0A3S5EUU3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

266748:EL218 RS10060
gene id: 266748:EL218_RS10060
uniprot id: A0A3S4UU39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

266748:EL218 RS04445
gene id: 266748:EL218_RS04445
uniprot id: A0A448NPR8
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

266748:EL218 RS11640
gene id: 266748:EL218_RS11640
uniprot id: A0A3S4UNF1
names: Similarity
messages: Belongs to the catalase family.

266748:EL218 RS11410
gene id: 266748:EL218_RS11410
uniprot id: A0A448NTM0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

266748:EL218 RS00155
gene id: 266748:EL218_RS00155
uniprot id: A0A448NM57
names: Similarity
messages: Belongs to the GARS family.

266748:EL218 RS00140
gene id: 266748:EL218_RS00140
uniprot id: A0A448NM61
names: Caution
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

266748:EL218 RS13755
gene id: 266748:EL218_RS13755
uniprot id: A0A448NUU9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MlaE permease family.
messages: Membrane

266748:EL218 RS12340
gene id: 266748:EL218_RS12340
uniprot id: A0A3S4UZW1
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

266748:EL218 RS03205
gene id: 266748:EL218_RS03205
uniprot id: A0A448NNW4
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

266748:EL218 RS09080
gene id: 266748:EL218_RS09080
uniprot id: A0A3S4UMP1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

266748:EL218 RS01175
gene id: 266748:EL218_RS01175
uniprot id: A0A3S4UPI2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

266748:EL218 RS05625
gene id: 266748:EL218_RS05625
uniprot id: A0A448NQ98
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

266748:EL218 RS10285
gene id: 266748:EL218_RS10285
uniprot id: A0A3S4UZ80
names: Function
names: Similarity
messages: Belongs to the HMBS family.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.

266748:EL218 RS01495
gene id: 266748:EL218_RS01495
uniprot id: A0A3S4UZ09
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

266748:EL218 RS07100
gene id: 266748:EL218_RS07100
uniprot id: A0A448NR75
names: Similarity
messages: Belongs to the CinA family.

266748:EL218 RS01030
gene id: 266748:EL218_RS01030
uniprot id: A0A3S4W0R0
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

266748:EL218 RS04560
gene id: 266748:EL218_RS04560
uniprot id: A0A3S5EUM2
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaved by autocatalysis into a large and a small subunit.
messages: This enzyme consists of two polypeptide chains, which are synthesized in precursor form from a single polypeptide.

266748:EL218 RS12890
gene id: 266748:EL218_RS12890
uniprot id: A0A3S4VGQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

266748:EL218 RS08865
gene id: 266748:EL218_RS08865
uniprot id: A0A448NS47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

266748:EL218 RS13825
gene id: 266748:EL218_RS13825
uniprot id: A0A3S4V4N8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

266748:EL218 RS12950
gene id: 266748:EL218_RS12950
uniprot id: A0A3S4WUF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

266748:EL218 RS10025
gene id: 266748:EL218_RS10025
uniprot id: A0A3S4VFQ4
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
messages: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.

266748:EL218 RS12000
gene id: 266748:EL218_RS12000
uniprot id: A0A3S4W5R5
names: Similarity
messages: Belongs to the deoxyhypusine synthase family.

266748:EL218 RS10355
gene id: 266748:EL218_RS10355
uniprot id: A0A3S4WTJ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

266748:EL218 RS09035
gene id: 266748:EL218_RS09035
uniprot id: A0A3S5EUU5
names: Similarity
messages: Belongs to the BshC family.

266748:EL218 RS14025
gene id: 266748:EL218_RS14025
uniprot id: A0A448NV05
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

266748:EL218 RS12510
gene id: 266748:EL218_RS12510
uniprot id: A0A448NU57
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

266748:EL218 RS05895
gene id: 266748:EL218_RS05895
uniprot id: A0A448NQL9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

266748:EL218 RS08665
gene id: 266748:EL218_RS08665
uniprot id: A0A448NS87
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

266748:EL218 RS01070
gene id: 266748:EL218_RS01070
uniprot id: A0A3S4VBF6
names: Similarity
messages: Belongs to the ParB family.

266748:EL218 RS11825
gene id: 266748:EL218_RS11825
uniprot id: A0A448NTU8
names: Subcellular Location Annotation
messages: Nucleus

266748:EL218 RS05820
gene id: 266748:EL218_RS05820
uniprot id: A0A3S4UXZ3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.
messages: Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU).
messages: Homotetramer.

266748:EL218 RS00405
gene id: 266748:EL218_RS00405
uniprot id: A0A448NMC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

266748:EL218 RS11140
gene id: 266748:EL218_RS11140
uniprot id: A0A448NTG9
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

266748:EL218 RS05640
gene id: 266748:EL218_RS05640
uniprot id: A0A3S4USS0
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

266748:EL218 RS10555
gene id: 266748:EL218_RS10555
uniprot id: A0A448NT53
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

266748:EL218 RS05560
gene id: 266748:EL218_RS05560
uniprot id: A0A448NQ75
names: Subcellular Location Annotation
messages: Membrane

266748:EL218 RS03265
gene id: 266748:EL218_RS03265
uniprot id: A0A448NNY2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 2 subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

266748:EL218 RS12325
gene id: 266748:EL218_RS12325
uniprot id: A0A3S4YUN5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

266748:EL218 RS10235
gene id: 266748:EL218_RS10235
uniprot id: A0A3S4V3E7
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

266748:EL218 RS11930
gene id: 266748:EL218_RS11930
uniprot id: A0A3S4W5Q5
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

266748:EL218 RS09135
gene id: 266748:EL218_RS09135
uniprot id: A0A448NS93
names: Similarity
messages: Belongs to the asparagine synthetase family.

266748:EL218 RS05395
gene id: 266748:EL218_RS05395
uniprot id: A0A3S4ULP9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

266748:EL218 RS08350
gene id: 266748:EL218_RS08350
uniprot id: A0A3S4V2T7
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

266748:EL218 RS00970
gene id: 266748:EL218_RS00970
uniprot id: A0A3S4UPC2
names: Similarity
messages: Belongs to the DEAD box helicase family.

266748:EL218 RS14280
gene id: 266748:EL218_RS14280
uniprot id: A0A448NV69
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

266748:EL218 RS10890
gene id: 266748:EL218_RS10890
uniprot id: A0A3S4V3M7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

266748:EL218 RS12870
gene id: 266748:EL218_RS12870
uniprot id: A0A3S4WUE8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

266748:EL218 RS03885
gene id: 266748:EL218_RS03885
uniprot id: A0A3S4WQH1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

266748:EL218 RS05260
gene id: 266748:EL218_RS05260
uniprot id: A0A3S5EUQ5
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

266748:EL218 RS00630
gene id: 266748:EL218_RS00630
uniprot id: A0A3S4UI65
names: Function
names: Similarity
messages: Belongs to the transglycosylase MltG family.
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

266748:EL218 RS08160
gene id: 266748:EL218_RS08160
uniprot id: A0A3S4W4M1
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

266748:EL218 RS00560
gene id: 266748:EL218_RS00560
uniprot id: A0A448NMG2
names: Function
names: Similarity
messages: Belongs to the peptidase S46 family.
messages: Catalyzes the removal of dipeptides from the N-terminus of oligopeptides.

266748:EL218 RS05145
gene id: 266748:EL218_RS05145
uniprot id: A0A3S4YSF9
names: Similarity
messages: Belongs to the type IA topoisomerase family.

266748:EL218 RS14275
gene id: 266748:EL218_RS14275
uniprot id: A0A3S4WUV5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

266748:EL218 RS01655
gene id: 266748:EL218_RS01655
uniprot id: A0A3S4UZ47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

266748:EL218 RS04875
gene id: 266748:EL218_RS04875
uniprot id: A0A448NQ04
names: Subcellular Location Annotation
messages: Membrane

266748:EL218 RS08145
gene id: 266748:EL218_RS08145
uniprot id: A0A448NRR7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

266748:EL218 RS14375
gene id: 266748:EL218_RS14375
uniprot id: A0A448NRC5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

266748:EL218 RS08890
gene id: 266748:EL218_RS08890
uniprot id: A0A3S4W4T6
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

266748:EL218 RS03830
gene id: 266748:EL218_RS03830
uniprot id: A0A3S4YHT0
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

266748:EL218 RS12390
gene id: 266748:EL218_RS12390
uniprot id: A0A3S4V452
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

266748:EL218 RS02750
gene id: 266748:EL218_RS02750
uniprot id: A0A448NNN1
names: Cofactor
names: Similarity
messages: Belongs to the monomeric-type IDH family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

266748:EL218 RS04105
gene id: 266748:EL218_RS04105
uniprot id: A0A448NPF6
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

266748:EL218 RS06225
gene id: 266748:EL218_RS06225
uniprot id: A0A448NQI6
names: Subcellular Location Annotation
messages: Membrane

266748:EL218 RS10570
gene id: 266748:EL218_RS10570
uniprot id: A0A3S4UZA9
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

266748:EL218 RS08540
gene id: 266748:EL218_RS08540
uniprot id: A0A3S4UTN1
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

266748:EL218 RS09925
gene id: 266748:EL218_RS09925
uniprot id: A0A448NSQ3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

266748:EL218 RS03130
gene id: 266748:EL218_RS03130
uniprot id: A0A3S4UW33
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the ferredoxin--NADP reductase type 2 family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

266748:EL218 RS02340
gene id: 266748:EL218_RS02340
uniprot id: A0A3S4UZJ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

266748:EL218 RS03975
gene id: 266748:EL218_RS03975
uniprot id: A0A448NPE8
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

266748:EL218 RS10370
gene id: 266748:EL218_RS10370
uniprot id: A0A3S4VFU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OmpP1/FadL family.
messages: Cell outer membrane
messages: Membrane

266748:EL218 RS11335
gene id: 266748:EL218_RS11335
uniprot id: A0A3S4UNC8
names: Similarity
messages: Belongs to the HMG-CoA lyase family.

266748:EL218 RS03455
gene id: 266748:EL218_RS03455
uniprot id: A0A3S4UJY6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

266748:EL218 RS00850
gene id: 266748:EL218_RS00850
uniprot id: A0A3S4YPE5
names: Function
names: Similarity
messages: Belongs to the PemK/MazF family.
messages: Toxic component of a type II toxin-antitoxin (TA) system.

266748:EL218 RS08860
gene id: 266748:EL218_RS08860
uniprot id: A0A448NS53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

266748:EL218 RS02135
gene id: 266748:EL218_RS02135
uniprot id: A0A3S4YGS4
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

266748:EL218 RS03140
gene id: 266748:EL218_RS03140
uniprot id: A0A3S4YHD2
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

266748:EL218 RS10010
gene id: 266748:EL218_RS10010
uniprot id: A0A3S4WTF7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of glycine to tRNA(Gly).
messages: Cytoplasm
messages: Homodimer.

266748:EL218 RS02435
gene id: 266748:EL218_RS02435
uniprot id: A0A3S5EUH7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Required for cell division and gliding motility.

266748:EL218 RS02025
gene id: 266748:EL218_RS02025
uniprot id: A0A448NN95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

266748:EL218 RS03970
gene id: 266748:EL218_RS03970
uniprot id: A0A448NPF4
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

266748:EL218 RS06235
gene id: 266748:EL218_RS06235
uniprot id: A0A448NQQ2
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.
messages: In the N-terminal section; belongs to the DHNA family.

266748:EL218 RS13095
gene id: 266748:EL218_RS13095
uniprot id: A0A448NUQ4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

266748:EL218 RS11990
gene id: 266748:EL218_RS11990
uniprot id: A0A3S4UUS1
names: Similarity
messages: Belongs to the heat shock protein 90 family.

266748:EL218 RS00670
gene id: 266748:EL218_RS00670
uniprot id: A0A448NME9
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

266748:EL218 RS02210
gene id: 266748:EL218_RS02210
uniprot id: A0A3S5EUH2
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

266748:EL218 RS13080
gene id: 266748:EL218_RS13080
uniprot id: A0A448NUH9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

266748:EL218 RS00930
gene id: 266748:EL218_RS00930
uniprot id: A0A3S4UYK2
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.

266748:EL218 RS05865
gene id: 266748:EL218_RS05865
uniprot id: A0A3S4V236
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

266748:EL218 RS12455
gene id: 266748:EL218_RS12455
uniprot id: A0A448NU81
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

266748:EL218 RS00125
gene id: 266748:EL218_RS00125
uniprot id: A0A448NM30
names: Similarity
messages: Belongs to the pirin family.

266748:EL218 RS08925
gene id: 266748:EL218_RS08925
uniprot id: A0A3S4WT18
names: Subcellular Location Annotation
messages: Membrane

266748:EL218 RS09445
gene id: 266748:EL218_RS09445
uniprot id: A0A448NSF0
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

266748:EL218 RS09870
gene id: 266748:EL218_RS09870
uniprot id: A0A3S4UU17
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.

266748:EL218 RS05650
gene id: 266748:EL218_RS05650
uniprot id: A0A448NQD4
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

266748:EL218 RS07430
gene id: 266748:EL218_RS07430
uniprot id: A0A448NRB3
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

266748:EL218 RS08150
gene id: 266748:EL218_RS08150
uniprot id: A0A3S4UTI5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

266748:EL218 RS11050
gene id: 266748:EL218_RS11050
uniprot id: A0A3S4YUA2
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

266748:EL218 RS02005
gene id: 266748:EL218_RS02005
uniprot id: A0A3S4UVE8
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

266748:EL218 RS02090
gene id: 266748:EL218_RS02090
uniprot id: A0A3S4YQ48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

266748:EL218 RS09100
gene id: 266748:EL218_RS09100
uniprot id: A0A3S4YTM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

266748:EL218 RS00995
gene id: 266748:EL218_RS00995
uniprot id: A0A3S4WNM4
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

266748:EL218 RS07160
gene id: 266748:EL218_RS07160
uniprot id: A0A3S4UT77
names: Cofactor
messages: Binds 1 copper ion per subunit, denoted as copper B.
messages: Binds 2 heme groups per subunit, denoted as high- and low-spin.

266748:EL218 RS09525
gene id: 266748:EL218_RS09525
uniprot id: A0A448NSI0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

266748:EL218 RS01280
gene id: 266748:EL218_RS01280
uniprot id: A0A448NMS3
names: Similarity
messages: Belongs to the peptidase S13 family.

266748:EL218 RS11925
gene id: 266748:EL218_RS11925
uniprot id: A0A3S4YLC5
names: Subcellular Location Annotation
messages: Membrane

266748:EL218 RS11625
gene id: 266748:EL218_RS11625
uniprot id: A0A448NTN1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

266748:EL218 RS14310
gene id: 266748:EL218_RS14310
uniprot id: A0A3S5EV03
names: Similarity
messages: Belongs to the peptidase S51 family.

266748:EL218 RS02345
gene id: 266748:EL218_RS02345
uniprot id: A0A3S4UJ98
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

266748:EL218 RS00250
gene id: 266748:EL218_RS00250
uniprot id: A0A3S4W075
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

266748:EL218 RS09990
gene id: 266748:EL218_RS09990
uniprot id: A0A3S4UU29
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

266748:EL218 RS09720
gene id: 266748:EL218_RS09720
uniprot id: A0A3S4UMW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

266748:EL218 RS03025
gene id: 266748:EL218_RS03025
uniprot id: A0A448NNT9
names: Similarity
messages: Belongs to the CvfB family.

266748:EL218 RS03115
gene id: 266748:EL218_RS03115
uniprot id: A0A448NNY0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

266748:EL218 RS06195
gene id: 266748:EL218_RS06195
uniprot id: A0A3S4V273
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

266748:EL218 RS04610
gene id: 266748:EL218_RS04610
uniprot id: A0A3S4VDZ0
names: Similarity
messages: Belongs to the glutamate synthase family.

266748:EL218 RS12885
gene id: 266748:EL218_RS12885
uniprot id: A0A448NUI1
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

266748:EL218 RS09490
gene id: 266748:EL218_RS09490
uniprot id: A0A448NSG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

266748:EL218 RS09025
gene id: 266748:EL218_RS09025
uniprot id: A0A448NS73
names: Similarity
messages: Belongs to the fabD family.

266748:EL218 RS02545
gene id: 266748:EL218_RS02545
uniprot id: A0A448NNK9
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

266748:EL218 RS02445
gene id: 266748:EL218_RS02445
uniprot id: A0A448NNI7
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

266748:EL218 RS12580
gene id: 266748:EL218_RS12580
uniprot id: A0A3S4YUR0
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

266748:EL218 RS04580
gene id: 266748:EL218_RS04580
uniprot id: A0A448NPT4
names: Subcellular Location Annotation
messages: Membrane

266748:EL218 RS12015
gene id: 266748:EL218_RS12015
uniprot id: A0A3S4WU35
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

266748:EL218 RS10515
gene id: 266748:EL218_RS10515
uniprot id: A0A3S4YKW1
names: Similarity
messages: Belongs to the UPF0102 family.

266748:EL218 RS08920
gene id: 266748:EL218_RS08920
uniprot id: A0A448NS79
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

266748:EL218 RS11760
gene id: 266748:EL218_RS11760
uniprot id: A0A448NTZ2
names: Subcellular Location Annotation
messages: Membrane

266748:EL218 RS13275
gene id: 266748:EL218_RS13275
uniprot id: A0A3S4V4H6
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

266748:EL218 RS05755
gene id: 266748:EL218_RS05755
uniprot id: A0A3S4W3Z6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Membrane

266748:EL218 RS11635
gene id: 266748:EL218_RS11635
uniprot id: A0A3S4WTX4
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

266748:EL218 RS04225
gene id: 266748:EL218_RS04225
uniprot id: A0A448NPK8
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

266748:EL218 RS13410
gene id: 266748:EL218_RS13410
uniprot id: A0A448NUW7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

266748:EL218 RS12930
gene id: 266748:EL218_RS12930
uniprot id: A0A3S4YLQ3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

266748:EL218 RS07555
gene id: 266748:EL218_RS07555
uniprot id: A0A448NRL9
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

266748:EL218 RS06305
gene id: 266748:EL218_RS06305
uniprot id: A0A3S4WSB2
names: Subcellular Location Annotation
messages: Membrane

266748:EL218 RS03110
gene id: 266748:EL218_RS03110
uniprot id: A0A3S4WPY7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

266748:EL218 RS12835
gene id: 266748:EL218_RS12835
uniprot id: A0A448NUH7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

266748:EL218 RS05635
gene id: 266748:EL218_RS05635
uniprot id: A0A448NQ79
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

266748:EL218 RS00725
gene id: 266748:EL218_RS00725
uniprot id: A0A448NMF7
names: Subcellular Location Annotation
messages: Membrane

266748:EL218 RS03850
gene id: 266748:EL218_RS03850
uniprot id: A0A3S4UK74
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

266748:EL218 RS10760
gene id: 266748:EL218_RS10760
uniprot id: A0A448NT81
names: Similarity
messages: Belongs to the ClpA/ClpB family.

266748:EL218 RS14175
gene id: 266748:EL218_RS14175
uniprot id: A0A448NV87
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

266748:EL218 RS00395
gene id: 266748:EL218_RS00395
uniprot id: A0A3S4YFN3
names: Similarity
messages: Belongs to the formate--tetrahydrofolate ligase family.

266748:EL218 RS11695
gene id: 266748:EL218_RS11695
uniprot id: A0A448NTQ7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

266748:EL218 RS00545
gene id: 266748:EL218_RS00545
uniprot id: A0A448NME2
names: Similarity
messages: Belongs to the peptidase M16 family.

266748:EL218 RS03145
gene id: 266748:EL218_RS03145
uniprot id: A0A448NNU5
names: Similarity
messages: Belongs to the FPG family.

266748:EL218 RS07305
gene id: 266748:EL218_RS07305
uniprot id: A0A3S4YT41
names: Similarity
messages: Belongs to the glycosyl hydrolase 25 family.

266748:EL218 RS05790
gene id: 266748:EL218_RS05790
uniprot id: A0A448NQA0
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

266748:EL218 RS12395
gene id: 266748:EL218_RS12395
uniprot id: A0A448NU63
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

266748:EL218 RS04045
gene id: 266748:EL218_RS04045
uniprot id: A0A448NPF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

266748:EL218 RS11780
gene id: 266748:EL218_RS11780
uniprot id: A0A3S4UZN5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

266748:EL218 RS03930
gene id: 266748:EL218_RS03930
uniprot id: A0A3S4YR75
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

266748:EL218 RS03330
gene id: 266748:EL218_RS03330
uniprot id: A0A448NNZ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

266748:EL218 RS11435
gene id: 266748:EL218_RS11435
uniprot id: A0A3S4WTV3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane

266748:EL218 RS06280
gene id: 266748:EL218_RS06280
uniprot id: A0A448NQV9
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

266748:EL218 RS08260
gene id: 266748:EL218_RS08260
uniprot id: A0A3S4V2S9
names: Similarity
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the malic enzymes family.

266748:EL218 RS01525
gene id: 266748:EL218_RS01525
uniprot id: A0A3S4UZ19
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

266748:EL218 RS12730
gene id: 266748:EL218_RS12730
uniprot id: A0A3S4YUT2
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

266748:EL218 RS09315
gene id: 266748:EL218_RS09315
uniprot id: A0A3S4YTP5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate.
messages: Cytoplasm

266748:EL218 RS08420
gene id: 266748:EL218_RS08420
uniprot id: A0A448NRX5
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.

266748:EL218 RS01095
gene id: 266748:EL218_RS01095
uniprot id: A0A3S4YG36
names: Similarity
messages: Belongs to the peptidase S8 family.

266748:EL218 RS08685
gene id: 266748:EL218_RS08685
uniprot id: A0A448NS15
names: Similarity
messages: Belongs to the RutC family.

266748:EL218 RS12400
gene id: 266748:EL218_RS12400
uniprot id: A0A448NU67
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

266748:EL218 RS14075
gene id: 266748:EL218_RS14075
uniprot id: A0A3S4UP62
names: Similarity
messages: Belongs to the barstar family.

266748:EL218 RS05125
gene id: 266748:EL218_RS05125
uniprot id: A0A3S4WRZ0
names: Similarity
messages: Belongs to the MQO family.

266748:EL218 RS01290
gene id: 266748:EL218_RS01290
uniprot id: A0A448NMZ5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA.
messages: Homodimer.

266748:EL218 RS01670
gene id: 266748:EL218_RS01670
uniprot id: A0A448NN19
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit A family.

266748:EL218 RS05090
gene id: 266748:EL218_RS05090
uniprot id: A0A3S5EUQ3
names: Similarity
messages: Belongs to the cysteine dioxygenase family.

266748:EL218 RS00600
gene id: 266748:EL218_RS00600
uniprot id: A0A3S4UI56
names: Function
messages: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.

266748:EL218 RS10900
gene id: 266748:EL218_RS10900
uniprot id: A0A3S4UN83
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

266748:EL218 RS00035
gene id: 266748:EL218_RS00035
uniprot id: A0A448NMB9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.

266748:EL218 RS06370
gene id: 266748:EL218_RS06370
uniprot id: A0A448NQM9
names: Similarity
messages: Belongs to the CIA30 family.

266748:EL218 RS06260
gene id: 266748:EL218_RS06260
uniprot id: A0A3S4UY31
names: Similarity
messages: Belongs to the asparagine synthetase family.

266748:EL218 RS00710
gene id: 266748:EL218_RS00710
uniprot id: A0A3S4UUN4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Monomer.

266748:EL218 RS03940
gene id: 266748:EL218_RS03940
uniprot id: A0A3S5EUK9
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-stimulated subfamily.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Requires K(+) for maximal activity.
messages: Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na(+) movement across the membrane.

266748:EL218 RS03100
gene id: 266748:EL218_RS03100
uniprot id: A0A448NNU6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

266748:EL218 RS01225
gene id: 266748:EL218_RS01225
uniprot id: A0A448NMR9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

266748:EL218 RS04410
gene id: 266748:EL218_RS04410
uniprot id: A0A3S4W2S9
names: Similarity
messages: Belongs to the TrpC family.

266748:EL218 RS00455
gene id: 266748:EL218_RS00455
uniprot id: A0A448NMD7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

266748:EL218 RS12675
gene id: 266748:EL218_RS12675
uniprot id: A0A3S4UV27
names: Similarity
messages: Belongs to the peptidase M16 family.

266748:EL218 RS04085
gene id: 266748:EL218_RS04085
uniprot id: A0A448NPD0
names: Subcellular Location Annotation
messages: Membrane

266748:EL218 RS12290
gene id: 266748:EL218_RS12290
uniprot id: A0A448NUA8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

266748:EL218 RS02970
gene id: 266748:EL218_RS02970
uniprot id: A0A448NNU9
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

266748:EL218 RS10295
gene id: 266748:EL218_RS10295
uniprot id: A0A448NSZ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

266748:EL218 RS09600
gene id: 266748:EL218_RS09600
uniprot id: A0A448NSR8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

266748:EL218 RS08730
gene id: 266748:EL218_RS08730
uniprot id: A0A448NS38
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

266748:EL218 RS04600
gene id: 266748:EL218_RS04600
uniprot id: A0A448NPU4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

266748:EL218 RS10885
gene id: 266748:EL218_RS10885
uniprot id: A0A448NTC6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

266748:EL218 RS13805
gene id: 266748:EL218_RS13805
uniprot id: A0A3S4YLZ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

266748:EL218 RS11205
gene id: 266748:EL218_RS11205
uniprot id: A0A3S4UUH3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

266748:EL218 RS06220
gene id: 266748:EL218_RS06220
uniprot id: A0A3S4VEK8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

266748:EL218 RS12380
gene id: 266748:EL218_RS12380
uniprot id: A0A448NU66
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

266748:EL218 RS03935
gene id: 266748:EL218_RS03935
uniprot id: A0A448NP98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

266748:EL218 RS05365
gene id: 266748:EL218_RS05365
uniprot id: A0A448NQ63
names: Function
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

266748:EL218 RS09680
gene id: 266748:EL218_RS09680
uniprot id: A0A3S5EUV2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein L14 (rplN).

266748:EL218 RS06900
gene id: 266748:EL218_RS06900
uniprot id: A0A3S4UY92
names: Similarity
messages: Belongs to the YjdM family.

266748:EL218 RS09105
gene id: 266748:EL218_RS09105
uniprot id: A0A448NSA6
names: Similarity
messages: Belongs to the ABC transporter superfamily.

266748:EL218 RS12130
gene id: 266748:EL218_RS12130
uniprot id: A0A448NU04
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

266748:EL218 RS07350
gene id: 266748:EL218_RS07350
uniprot id: A0A3S4W4D9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

266748:EL218 RS10665
gene id: 266748:EL218_RS10665
uniprot id: A0A3S4UZC2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase D family. Cardiolipin synthase subfamily.
messages: Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
messages: Cell membrane
messages: Membrane

266748:EL218 RS13030
gene id: 266748:EL218_RS13030
uniprot id: A0A3S4WUH2
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

266748:EL218 RS06190
gene id: 266748:EL218_RS06190
uniprot id: A0A3S4W435
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

266748:EL218 RS08645
gene id: 266748:EL218_RS08645
uniprot id: A0A3S4V2X1
names: Subcellular Location Annotation
messages: Membrane

266748:EL218 RS12135
gene id: 266748:EL218_RS12135
uniprot id: A0A448NU00
names: Similarity
messages: Belongs to the arginase family.

266748:EL218 RS10315
gene id: 266748:EL218_RS10315
uniprot id: A0A448NSY7
names: Subcellular Location Annotation
messages: Membrane

266748:EL218 RS09350
gene id: 266748:EL218_RS09350
uniprot id: A0A3S4WT80
names: Subcellular Location Annotation
messages: Membrane

266748:EL218 RS10225
gene id: 266748:EL218_RS10225
uniprot id: A0A3S4UU59
names: Subcellular Location Annotation
messages: Membrane

266748:EL218 RS05340
gene id: 266748:EL218_RS05340
uniprot id: A0A3S4UXU7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

266748:EL218 RS10340
gene id: 266748:EL218_RS10340
uniprot id: A0A3S4V3G2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

266748:EL218 RS12440
gene id: 266748:EL218_RS12440
uniprot id: A0A3S4UUY9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

266748:EL218 RS00815
gene id: 266748:EL218_RS00815
uniprot id: A0A3S4VB92
names: Similarity
messages: Belongs to the AHA1 family.

266748:EL218 RS01730
gene id: 266748:EL218_RS01730
uniprot id: A0A448NN87
names: Similarity
messages: Belongs to the AB hydrolase superfamily.

266748:EL218 RS01435
gene id: 266748:EL218_RS01435
uniprot id: A0A3S4YGB3
names: Function
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

266748:EL218 RS12260
gene id: 266748:EL218_RS12260
uniprot id: A0A3S4UUW1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

266748:EL218 RS00640
gene id: 266748:EL218_RS00640
uniprot id: A0A448NMG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family.
messages: Membrane

266748:EL218 RS04405
gene id: 266748:EL218_RS04405
uniprot id: A0A3S4YI68
names: Similarity
messages: Belongs to the TrpF family.

266748:EL218 RS10610
gene id: 266748:EL218_RS10610
uniprot id: A0A448NT48
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family. GuaC type 1 subfamily.
messages: Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.
messages: Homotetramer.

266748:EL218 RS11480
gene id: 266748:EL218_RS11480
uniprot id: A0A3S4UZK3
names: Subcellular Location Annotation
messages: Membrane

266748:EL218 RS13235
gene id: 266748:EL218_RS13235
uniprot id: A0A3S4UNY7
names: Subcellular Location Annotation
messages: Membrane

266748:EL218 RS10520
gene id: 266748:EL218_RS10520
uniprot id: A0A3S4W5A4
names: Similarity
messages: Belongs to the peptidase S66 family.

266748:EL218 RS06435
gene id: 266748:EL218_RS06435
uniprot id: A0A448NQU9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0324 family.
messages: Membrane

266748:EL218 RS04700
gene id: 266748:EL218_RS04700
uniprot id: A0A3S4VE12
names: Similarity
messages: Belongs to the peptidase S13 family.

266748:EL218 RS05705
gene id: 266748:EL218_RS05705
uniprot id: A0A3S4VEF4
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.

266748:EL218 RS11950
gene id: 266748:EL218_RS11950
uniprot id: A0A448NTV5
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

266748:EL218 RS04925
gene id: 266748:EL218_RS04925
uniprot id: A0A3S4VE70
names: Function
names: Similarity
messages: Belongs to the RlpA family.
messages: Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.

266748:EL218 RS04305
gene id: 266748:EL218_RS04305
uniprot id: A0A3S5EUL7
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

266748:EL218 RS12970
gene id: 266748:EL218_RS12970
uniprot id: A0A448NUF9
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

266748:EL218 RS07610
gene id: 266748:EL218_RS07610
uniprot id: A0A448NRI7
names: Similarity
messages: Belongs to the peptidase M4 family.

266748:EL218 RS13930
gene id: 266748:EL218_RS13930
uniprot id: A0A3S4YLZ9
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

266748:EL218 RS11125
gene id: 266748:EL218_RS11125
uniprot id: A0A448NTF2
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

266748:EL218 RS13770
gene id: 266748:EL218_RS13770
uniprot id: A0A448NUW0
names: Subcellular Location Annotation
messages: Membrane

266748:EL218 RS12120
gene id: 266748:EL218_RS12120
uniprot id: A0A448NU07
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

266748:EL218 RS02365
gene id: 266748:EL218_RS02365
uniprot id: A0A3S4UQA5
names: Similarity
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

266748:EL218 RS07920
gene id: 266748:EL218_RS07920
uniprot id: A0A448NRK8
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

266748:EL218 RS00475
gene id: 266748:EL218_RS00475
uniprot id: A0A3S4UUI4
names: Similarity
messages: Belongs to the Nudix hydrolase family.

266748:EL218 RS09545
gene id: 266748:EL218_RS09545
uniprot id: A0A3S4UMU0
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

266748:EL218 RS09685
gene id: 266748:EL218_RS09685
uniprot id: A0A3S4UZ10
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

266748:EL218 RS04265
gene id: 266748:EL218_RS04265
uniprot id: A0A3S4URG6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

266748:EL218 RS01160
gene id: 266748:EL218_RS01160
uniprot id: A0A3S4YPM2
names: Similarity
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.

266748:EL218 RS12830
gene id: 266748:EL218_RS12830
uniprot id: A0A448NUG7
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

266748:EL218 RS12865
gene id: 266748:EL218_RS12865
uniprot id: A0A3S4V4B8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

266748:EL218 RS06290
gene id: 266748:EL218_RS06290
uniprot id: A0A3S4W443
names: Subcellular Location Annotation
messages: Membrane

266748:EL218 RS08240
gene id: 266748:EL218_RS08240
uniprot id: A0A448NRR4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

266748:EL218 RS05390
gene id: 266748:EL218_RS05390
uniprot id: A0A448NQ33
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

266748:EL218 RS01665
gene id: 266748:EL218_RS01665
uniprot id: A0A448NN21
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

266748:EL218 RS02170
gene id: 266748:EL218_RS02170
uniprot id: A0A448NNB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Membrane

266748:EL218 RS00985
gene id: 266748:EL218_RS00985
uniprot id: A0A448NMN4
names: Similarity
messages: Belongs to the UPF0111 family.

266748:EL218 RS12370
gene id: 266748:EL218_RS12370
uniprot id: A0A448NU28
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

266748:EL218 RS01500
gene id: 266748:EL218_RS01500
uniprot id: A0A3S4UIR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

266748:EL218 RS00755
gene id: 266748:EL218_RS00755
uniprot id: A0A3S4VB77
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. METTL16/RlmF family.
messages: Cytoplasm
messages: Specifically methylates the adenine in position 1618 of 23S rRNA.

266748:EL218 RS09450
gene id: 266748:EL218_RS09450
uniprot id: A0A3S4VFJ7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

266748:EL218 RS11065
gene id: 266748:EL218_RS11065
uniprot id: A0A448NTD5
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

266748:EL218 RS07840
gene id: 266748:EL218_RS07840
uniprot id: A0A3S4UYH2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

266748:EL218 RS05845
gene id: 266748:EL218_RS05845
uniprot id: A0A448NQK9
names: Similarity
messages: Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family.

266748:EL218 RS10300
gene id: 266748:EL218_RS10300
uniprot id: A0A3S4UU69
names: Similarity
messages: Belongs to the MreC family.

266748:EL218 RS05685
gene id: 266748:EL218_RS05685
uniprot id: A0A448NQ91
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

266748:EL218 RS07825
gene id: 266748:EL218_RS07825
uniprot id: A0A3S4VF26
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

266748:EL218 RS07070
gene id: 266748:EL218_RS07070
uniprot id: A0A3S4WSJ0
names: Similarity
messages: Belongs to the peptidase M13 family.

266748:EL218 RS04390
gene id: 266748:EL218_RS04390
uniprot id: A0A3S4VD97
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

266748:EL218 RS11900
gene id: 266748:EL218_RS11900
uniprot id: A0A3S4VGB4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Forms a complex with TatC.
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.

266748:EL218 RS12755
gene id: 266748:EL218_RS12755
uniprot id: A0A448NUE5
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

266748:EL218 RS04725
gene id: 266748:EL218_RS04725
uniprot id: A0A3S4YJ13
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

266748:EL218 RS12350
gene id: 266748:EL218_RS12350
uniprot id: A0A448NU58
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

266748:EL218 RS02775
gene id: 266748:EL218_RS02775
uniprot id: A0A448NNN6
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

266748:EL218 RS13475
gene id: 266748:EL218_RS13475
uniprot id: A0A448NUV3
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

266748:EL218 RS04400
gene id: 266748:EL218_RS04400
uniprot id: A0A3S4UWU1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

266748:EL218 RS14180
gene id: 266748:EL218_RS14180
uniprot id: A0A448NV94
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

266748:EL218 RS13210
gene id: 266748:EL218_RS13210
uniprot id: A0A3S4W675
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

266748:EL218 RS09015
gene id: 266748:EL218_RS09015
uniprot id: A0A3S4YTL7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Cytoplasm
messages: Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.

266748:EL218 RS13135
gene id: 266748:EL218_RS13135
uniprot id: A0A3S4VGU3
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

266748:EL218 RS11670
gene id: 266748:EL218_RS11670
uniprot id: A0A448NTR0
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

266748:EL218 RS12615
gene id: 266748:EL218_RS12615
uniprot id: A0A448NU93
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

266748:EL218 RS12435
gene id: 266748:EL218_RS12435
uniprot id: A0A3S4UZX1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

266748:EL218 RS08290
gene id: 266748:EL218_RS08290
uniprot id: A0A3S4YTE7
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
messages: Part of the 50S ribosomal subunit.

266748:EL218 RS10790
gene id: 266748:EL218_RS10790
uniprot id: A0A3S4V3L8
names: Subcellular Location Annotation
messages: Membrane

266748:EL218 RS11010
gene id: 266748:EL218_RS11010
uniprot id: A0A3S4W5F4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

266748:EL218 RS13515
gene id: 266748:EL218_RS13515
uniprot id: A0A448NUQ9
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

266748:EL218 RS01395
gene id: 266748:EL218_RS01395
uniprot id: A0A448NMV5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

266748:EL218 RS00920
gene id: 266748:EL218_RS00920
uniprot id: A0A3S4UPB0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Forms a complex with TatC.
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.

266748:EL218 RS12565
gene id: 266748:EL218_RS12565
uniprot id: A0A448NU82
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

266748:EL218 RS10480
gene id: 266748:EL218_RS10480
uniprot id: A0A448NT00
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

266748:EL218 RS10275
gene id: 266748:EL218_RS10275
uniprot id: A0A448NSX6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.

266748:EL218 RS01695
gene id: 266748:EL218_RS01695
uniprot id: A0A3S4W158
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

266748:EL218 RS00870
gene id: 266748:EL218_RS00870
uniprot id: A0A448NMI6
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF2.
messages: Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.

266748:EL218 RS10230
gene id: 266748:EL218_RS10230
uniprot id: A0A3S4YKS6
names: Similarity
messages: Belongs to the DprA/Smf family.

266748:EL218 RS00875
gene id: 266748:EL218_RS00875
uniprot id: A0A3S4W0M7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

266748:EL218 RS12025
gene id: 266748:EL218_RS12025
uniprot id: A0A3S4UNJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

266748:EL218 RS02400
gene id: 266748:EL218_RS02400
uniprot id: A0A3S4UQB5
names: Subcellular Location Annotation
messages: Membrane

266748:EL218 RS08155
gene id: 266748:EL218_RS08155
uniprot id: A0A3S4YK47
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

266748:EL218 RS05360
gene id: 266748:EL218_RS05360
uniprot id: A0A3S4YJA9
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

266748:EL218 RS05180
gene id: 266748:EL218_RS05180
uniprot id: A0A3S4YJ97
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpC family.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

266748:EL218 RS00115
gene id: 266748:EL218_RS00115
uniprot id: A0A3S4UNT5
names: Subcellular Location Annotation
messages: Membrane

266748:EL218 RS10550
gene id: 266748:EL218_RS10550
uniprot id: A0A448NTC1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

266748:EL218 RS10495
gene id: 266748:EL218_RS10495
uniprot id: A0A3S4UU87
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

266748:EL218 RS03655
gene id: 266748:EL218_RS03655
uniprot id: A0A3S4UK36
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

266748:EL218 RS03820
gene id: 266748:EL218_RS03820
uniprot id: A0A448NPC1
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

266748:EL218 RS01255
gene id: 266748:EL218_RS01255
uniprot id: A0A3S4UPK4
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

266748:EL218 RS12415
gene id: 266748:EL218_RS12415
uniprot id: A0A3S4VGJ1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

266748:EL218 RS05880
gene id: 266748:EL218_RS05880
uniprot id: A0A3S4VEH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

266748:EL218 RS10855
gene id: 266748:EL218_RS10855
uniprot id: A0A448NT77
names: Subcellular Location Annotation
messages: Membrane

266748:EL218 RS08555
gene id: 266748:EL218_RS08555
uniprot id: A0A3S4V2W2
names: Function
names: Similarity
messages: Belongs to the TrhO family.
messages: Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.

266748:EL218 RS07390
gene id: 266748:EL218_RS07390
uniprot id: A0A3S5EUS8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
messages: Cytoplasm

266748:EL218 RS00825
gene id: 266748:EL218_RS00825
uniprot id: A0A448NMH6
names: Similarity
messages: Belongs to the AHA1 family.

266748:EL218 RS11845
gene id: 266748:EL218_RS11845
uniprot id: A0A3S4YUH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

266748:EL218 RS04775
gene id: 266748:EL218_RS04775
uniprot id: A0A448NPS6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Membrane

266748:EL218 RS00340
gene id: 266748:EL218_RS00340
uniprot id: A0A448NMA0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

266748:EL218 RS06205
gene id: 266748:EL218_RS06205
uniprot id: A0A3S4WSA3
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

266748:EL218 RS00120
gene id: 266748:EL218_RS00120
uniprot id: A0A3S4YFF2
names: Similarity
messages: Belongs to the peptidase M16 family.

266748:EL218 RS12405
gene id: 266748:EL218_RS12405
uniprot id: A0A3S4WU90
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

266748:EL218 RS07270
gene id: 266748:EL218_RS07270
uniprot id: A0A3S4YJU4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein S19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein S19.

266748:EL218 RS09995
gene id: 266748:EL218_RS09995
uniprot id: A0A3S4YKP8
names: Subcellular Location Annotation
messages: Membrane

266748:EL218 RS13000
gene id: 266748:EL218_RS13000
uniprot id: A0A3S4YLR1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. tRNA (adenine-N(6)-)-methyltransferase family.
messages: Cytoplasm
messages: Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC).

266748:EL218 RS07365
gene id: 266748:EL218_RS07365
uniprot id: A0A448NRH8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

266748:EL218 RS01630
gene id: 266748:EL218_RS01630
uniprot id: A0A448NMY3
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

266748:EL218 RS13310
gene id: 266748:EL218_RS13310
uniprot id: A0A448NUU7
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 3 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

266748:EL218 RS04065
gene id: 266748:EL218_RS04065
uniprot id: A0A3S4W2K0
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

266748:EL218 RS04090
gene id: 266748:EL218_RS04090
uniprot id: A0A448NPK2
names: Similarity
messages: Belongs to the glutathione peroxidase family.

266748:EL218 RS12875
gene id: 266748:EL218_RS12875
uniprot id: A0A448NUC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

266748:EL218 RS09065
gene id: 266748:EL218_RS09065
uniprot id: A0A3S4V310
names: Similarity
messages: Belongs to the SusD family.

266748:EL218 RS03875
gene id: 266748:EL218_RS03875
uniprot id: A0A448NPC8
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

266748:EL218 RS02705
gene id: 266748:EL218_RS02705
uniprot id: A0A448NNL7
names: Subcellular Location Annotation
messages: Membrane

266748:EL218 RS00685
gene id: 266748:EL218_RS00685
uniprot id: A0A448NMN8
names: Subcellular Location Annotation
messages: Membrane

266748:EL218 RS12910
gene id: 266748:EL218_RS12910
uniprot id: A0A3S5EUY9
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

266748:EL218 RS12640
gene id: 266748:EL218_RS12640
uniprot id: A0A3S4UNR9
names: Caution
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IcmF family.
messages: Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly.
messages: Homodimer.
messages: Is composed of four functional domains: the N-terminal 5'-deoxyadenosylcobalamin binding region that is homologous to the small subunit of ICM (IcmB), a middle P-loop GTPase domain (MeaI) that likely acts as a chaperone for ICM, a structured linker region involved in dimer formation, and a C-terminal part that is homologous to the large substrate-binding subunit of ICM (IcmA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

266748:EL218 RS08750
gene id: 266748:EL218_RS08750
uniprot id: A0A448NS21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

266748:EL218 RS11100
gene id: 266748:EL218_RS11100
uniprot id: A0A3S4UZG3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I fumarase family.
messages: Catalyzes the reversible hydration of fumarate to (S)-malate.
messages: Homodimer.

266748:EL218 RS03985
gene id: 266748:EL218_RS03985
uniprot id: A0A448NPA6
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

266748:EL218 RS00910
gene id: 266748:EL218_RS00910
uniprot id: A0A448NMK9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

266748:EL218 RS00090
gene id: 266748:EL218_RS00090
uniprot id: A0A448NM47
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

266748:EL218 RS09330
gene id: 266748:EL218_RS09330
uniprot id: A0A3S4UTV9
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

266748:EL218 RS02600
gene id: 266748:EL218_RS02600
uniprot id: A0A448NNJ9
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

266748:EL218 RS07415
gene id: 266748:EL218_RS07415
uniprot id: A0A3S4YJW8
names: Subcellular Location Annotation
messages: Membrane

266748:EL218 RS03890
gene id: 266748:EL218_RS03890
uniprot id: A0A448NPF7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

266748:EL218 RS00805
gene id: 266748:EL218_RS00805
uniprot id: A0A3S4WNI2
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the peroxiredoxin family. Tpx subfamily.
messages: Homodimer.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. In this atypical 2-Cys peroxiredoxin, C(R) is present in the same subunit to form an intramolecular disulfide. The disulfide is subsequently reduced by thioredoxin.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

266748:EL218 RS02405
gene id: 266748:EL218_RS02405
uniprot id: A0A448NNF7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase Z family.
messages: Binds 2 Zn(2+) ions.
messages: Homodimer.
messages: Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.

266748:EL218 RS07125
gene id: 266748:EL218_RS07125
uniprot id: A0A448NR83
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

266748:EL218 RS10290
gene id: 266748:EL218_RS10290
uniprot id: A0A448NSX9
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

266748:EL218 RS00675
gene id: 266748:EL218_RS00675
uniprot id: A0A448NME4
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

266748:EL218 RS01490
gene id: 266748:EL218_RS01490
uniprot id: A0A3S4W119
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: In the N-terminal section; belongs to the histidinol-phosphatase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

266748:EL218 RS05595
gene id: 266748:EL218_RS05595
uniprot id: A0A448NQ65
names: Subcellular Location Annotation
messages: Membrane

266748:EL218 RS07175
gene id: 266748:EL218_RS07175
uniprot id: A0A448NR82
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.

266748:EL218 RS11315
gene id: 266748:EL218_RS11315
uniprot id: A0A3S4V3R0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

266748:EL218 RS12040
gene id: 266748:EL218_RS12040
uniprot id: A0A3S5EUX8
names: Activity Regulation
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.

266748:EL218 RS14295
gene id: 266748:EL218_RS14295
uniprot id: A0A3S4VH71
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

266748:EL218 RS09280
gene id: 266748:EL218_RS09280
uniprot id: A0A448NSC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

266748:EL218 RS03450
gene id: 266748:EL218_RS03450
uniprot id: A0A3S4V066
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

266748:EL218 RS06490
gene id: 266748:EL218_RS06490
uniprot id: A0A3S4YJL8
names: Caution
names: Function
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the 2'-O methylation of guanosine at position 18 in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

266748:EL218 RS03225
gene id: 266748:EL218_RS03225
uniprot id: A0A3S5EUJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

266748:EL218 RS13040
gene id: 266748:EL218_RS13040
uniprot id: A0A3S4UNW7
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

266748:EL218 RS14380
gene id: 266748:EL218_RS14380
uniprot id: A0A448NRD4
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

266748:EL218 RS03165
gene id: 266748:EL218_RS03165
uniprot id: A0A3S4V005
names: Subcellular Location Annotation
messages: Endoplasmic reticulum
messages: Golgi apparatus
messages: Lysosome
messages: Secreted

266748:EL218 RS12375
gene id: 266748:EL218_RS12375
uniprot id: A0A448NU52
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

266748:EL218 RS06480
gene id: 266748:EL218_RS06480
uniprot id: A0A3S4UT06
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

266748:EL218 RS03480
gene id: 266748:EL218_RS03480
uniprot id: A0A448NP43
names: Similarity
messages: Belongs to the ATPase epsilon chain family.

266748:EL218 RS01085
gene id: 266748:EL218_RS01085
uniprot id: A0A448NMQ3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

266748:EL218 RS14045
gene id: 266748:EL218_RS14045
uniprot id: A0A3S4W6F6
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

266748:EL218 RS11885
gene id: 266748:EL218_RS11885
uniprot id: A0A3S4V3X5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the GTP cyclohydrolase II family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.

266748:EL218 RS05135
gene id: 266748:EL218_RS05135
uniprot id: A0A3S4ULM2
names: Similarity
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.

266748:EL218 RS07240
gene id: 266748:EL218_RS07240
uniprot id: A0A3S5EUS6
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

266748:EL218 RS05835
gene id: 266748:EL218_RS05835
uniprot id: A0A3S4YJF0
names: Cofactor
messages: Can also use Mn(2+) ion.

266748:EL218 RS06470
gene id: 266748:EL218_RS06470
uniprot id: A0A448NQQ6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

266748:EL218 RS04800
gene id: 266748:EL218_RS04800
uniprot id: A0A3S4W3P2
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

266748:EL218 RS03880
gene id: 266748:EL218_RS03880
uniprot id: A0A3S4V0H1
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

266748:EL218 RS11605
gene id: 266748:EL218_RS11605
uniprot id: A0A3S4YL80
names: Subcellular Location Annotation
messages: Mitochondrion

266748:EL218 RS02590
gene id: 266748:EL218_RS02590
uniprot id: A0A448NNM2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

266748:EL218 RS08705
gene id: 266748:EL218_RS08705
uniprot id: A0A448NS10
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CutC family.
messages: Cytoplasm
messages: Once thought to be involved in copper homeostasis, experiments in E.coli have shown this is not the case.

266748:EL218 RS07750
gene id: 266748:EL218_RS07750
uniprot id: A0A3S4YT88
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

266748:EL218 RS03905
gene id: 266748:EL218_RS03905
uniprot id: A0A448NPB3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

266748:EL218 RS08615
gene id: 266748:EL218_RS08615
uniprot id: A0A3S4W4R6
names: Similarity
messages: Belongs to the RecJ family.

266748:EL218 RS03005
gene id: 266748:EL218_RS03005
uniprot id: A0A3S4UZX9
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

266748:EL218 RS05265
gene id: 266748:EL218_RS05265
uniprot id: A0A3S4UXT8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

266748:EL218 RS07105
gene id: 266748:EL218_RS07105
uniprot id: A0A448NR55
names: Similarity
messages: Belongs to the calycin superfamily. Lipocalin family.

266748:EL218 RS10700
gene id: 266748:EL218_RS10700
uniprot id: A0A448NT82
names: Similarity
messages: Belongs to the peptidase S9A family.

266748:EL218 RS12990
gene id: 266748:EL218_RS12990
uniprot id: A0A3S4V042
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

266748:EL218 RS08210
gene id: 266748:EL218_RS08210
uniprot id: A0A448NRS5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

266748:EL218 RS05190
gene id: 266748:EL218_RS05190
uniprot id: A0A3S4V1X8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpA family.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds the extracellular potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

266748:EL218 RS05380
gene id: 266748:EL218_RS05380
uniprot id: A0A448NQ96
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

266748:EL218 RS11005
gene id: 266748:EL218_RS11005
uniprot id: A0A3S4YL17
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.

266748:EL218 RS00105
gene id: 266748:EL218_RS00105
uniprot id: A0A3S4YNY4
names: Similarity
messages: Belongs to the SusD family.

266748:EL218 RS01405
gene id: 266748:EL218_RS01405
uniprot id: A0A448NMY9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

266748:EL218 RS09075
gene id: 266748:EL218_RS09075
uniprot id: A0A3S4WT42
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

266748:EL218 RS02230
gene id: 266748:EL218_RS02230
uniprot id: A0A3S4WPG2
names: Similarity
messages: Belongs to the histone deacetylase family.

266748:EL218 RS02325
gene id: 266748:EL218_RS02325
uniprot id: A0A448NNF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

266748:EL218 RS00580
gene id: 266748:EL218_RS00580
uniprot id: A0A3S4YFS6
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
messages: Synthesizes alpha-1,4-glucan chains using ADP-glucose.

266748:EL218 RS11260
gene id: 266748:EL218_RS11260
uniprot id: A0A3S4VG46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

266748:EL218 RS09530
gene id: 266748:EL218_RS09530
uniprot id: A0A3S4V360
names: Subcellular Location Annotation
messages: Secreted

266748:EL218 RS07965
gene id: 266748:EL218_RS07965
uniprot id: A0A3S4W4K7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reduced FMN (FMNH(2)).

266748:EL218 RS03765
gene id: 266748:EL218_RS03765
uniprot id: A0A3S4VCW5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

266748:EL218 RS09475
gene id: 266748:EL218_RS09475
uniprot id: A0A3S4UYZ0
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

266748:EL218 RS03195
gene id: 266748:EL218_RS03195
uniprot id: A0A3S4W206
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

266748:EL218 RS14550
gene id: 266748:EL218_RS14550
uniprot id: A0A3S4W4V3
names: Similarity
messages: Belongs to the SusD family.

266748:EL218 RS03275
gene id: 266748:EL218_RS03275
uniprot id: A0A3S4VCM5
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

266748:EL218 RS07265
gene id: 266748:EL218_RS07265
uniprot id: A0A3S4UT86
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

266748:EL218 RS03800
gene id: 266748:EL218_RS03800
uniprot id: A0A3S4VCX4
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

266748:EL218 RS07205
gene id: 266748:EL218_RS07205
uniprot id: A0A3S4UM62
names: Subcellular Location Annotation
messages: Membrane

266748:EL218 RS01040
gene id: 266748:EL218_RS01040
uniprot id: A0A448NMN7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

266748:EL218 RS07410
gene id: 266748:EL218_RS07410
uniprot id: A0A3S4UTA5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

266748:EL218 RS10585
gene id: 266748:EL218_RS10585
uniprot id: A0A3S4YKW9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

266748:EL218 RS13285
gene id: 266748:EL218_RS13285
uniprot id: A0A3S4WUK8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YejK family.
messages: nucleoid

266748:EL218 RS11415
gene id: 266748:EL218_RS11415
uniprot id: A0A448NTK6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

266748:EL218 RS12525
gene id: 266748:EL218_RS12525
uniprot id: A0A3S4UZY0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

266748:EL218 RS11380
gene id: 266748:EL218_RS11380
uniprot id: A0A3S4UZJ1
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

266748:EL218 RS03280
gene id: 266748:EL218_RS03280
uniprot id: A0A3S5EUJ4
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

266748:EL218 RS04945
gene id: 266748:EL218_RS04945
uniprot id: A0A3S4USI7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

266748:EL218 RS02710
gene id: 266748:EL218_RS02710
uniprot id: A0A448NNM8
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

266748:EL218 RS08325
gene id: 266748:EL218_RS08325
uniprot id: A0A448NRT8
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

266748:EL218 RS14215
gene id: 266748:EL218_RS14215
uniprot id: A0A448NV59
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

266748:EL218 RS11795
gene id: 266748:EL218_RS11795
uniprot id: A0A3S4W5N7
names: Similarity
messages: Belongs to the Skp family.

266748:EL218 RS08175
gene id: 266748:EL218_RS08175
uniprot id: A0A3S4WSU6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

266748:EL218 RS13360
gene id: 266748:EL218_RS13360
uniprot id: A0A448NUV6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

266748:EL218 RS02805
gene id: 266748:EL218_RS02805
uniprot id: A0A448NNN8
names: Subcellular Location Annotation
messages: Membrane

266748:EL218 RS05645
gene id: 266748:EL218_RS05645
uniprot id: A0A3S4YJD1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
messages: Homodimer.

266748:EL218 RS03715
gene id: 266748:EL218_RS03715
uniprot id: A0A3S5EUK4
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 2 residues (Tyr-54 and Arg-57) present in a large hydrophobic pocket are probably involved in substrate specificity. They are important for desuccinylation activity, but dispensable for deacetylation activity.
messages: Belongs to the sirtuin family. Class III subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form.

266748:EL218 RS09950
gene id: 266748:EL218_RS09950
uniprot id: A0A3S4YTV9
names: Similarity
messages: Belongs to the beta-eliminating lyase family.

266748:EL218 RS13460
gene id: 266748:EL218_RS13460
uniprot id: A0A448NUP1
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

266748:EL218 RS05980
gene id: 266748:EL218_RS05980
uniprot id: A0A3S4WS76
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

266748:EL218 RS02000
gene id: 266748:EL218_RS02000
uniprot id: A0A3S4YQ30
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

266748:EL218 RS03180
gene id: 266748:EL218_RS03180
uniprot id: A0A3S4YQR4
names: Similarity
messages: Belongs to the peptidase S9C family.

266748:EL218 RS03565
gene id: 266748:EL218_RS03565
uniprot id: A0A3S4WQ93
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

266748:EL218 RS05715
gene id: 266748:EL218_RS05715
uniprot id: A0A448NQA7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

266748:EL218 RS12710
gene id: 266748:EL218_RS12710
uniprot id: A0A3S4VGN4
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

266748:EL218 RS10260
gene id: 266748:EL218_RS10260
uniprot id: A0A3S4VFT3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

266748:EL218 RS02715
gene id: 266748:EL218_RS02715
uniprot id: A0A3S4UZS6
names: Subcellular Location Annotation
messages: Membrane

266748:EL218 RS09345
gene id: 266748:EL218_RS09345
uniprot id: A0A3S4V337
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

266748:EL218 RS00605
gene id: 266748:EL218_RS00605
uniprot id: A0A448NMF1
names: Similarity
messages: Belongs to the peptidase S8 family.

266748:EL218 RS07405
gene id: 266748:EL218_RS07405
uniprot id: A0A448NRB4
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

266748:EL218 RS09640
gene id: 266748:EL218_RS09640
uniprot id: A0A448NSL8
names: Similarity
messages: Belongs to the peptidase S9A family.

266748:EL218 RS02645
gene id: 266748:EL218_RS02645
uniprot id: A0A3S4WPQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uridine kinase family.
messages: Cytoplasm

266748:EL218 RS13035
gene id: 266748:EL218_RS13035
uniprot id: A0A448NUM1
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

266748:EL218 RS02945
gene id: 266748:EL218_RS02945
uniprot id: A0A3S4YH95
names: Similarity
messages: Belongs to the SIS family. GutQ/KpsF subfamily.

266748:EL218 RS01850
gene id: 266748:EL218_RS01850
uniprot id: A0A448NN48
names: Function
names: Similarity
messages: Belongs to the catalase family. HPII subfamily.
messages: Serves to protect cells from the toxic effects of hydrogen peroxide.

266748:EL218 RS11180
gene id: 266748:EL218_RS11180
uniprot id: A0A3S4YUB0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

266748:EL218 RS11225
gene id: 266748:EL218_RS11225
uniprot id: A0A448NTH0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

266748:EL218 RS05060
gene id: 266748:EL218_RS05060
uniprot id: A0A3S4V1W3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 3B subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

266748:EL218 RS07915
gene id: 266748:EL218_RS07915
uniprot id: A0A448NRL2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.
messages: In the N-terminal section; belongs to the DHBP synthase family.

266748:EL218 RS13200
gene id: 266748:EL218_RS13200
uniprot id: A0A448NUQ0
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

266748:EL218 RS08360
gene id: 266748:EL218_RS08360
uniprot id: A0A448NS27
names: Similarity
messages: Belongs to the glycosyl hydrolase 63 family.

266748:EL218 RS08505
gene id: 266748:EL218_RS08505
uniprot id: A0A448NRZ1
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

266748:EL218 RS01895
gene id: 266748:EL218_RS01895
uniprot id: A0A3S4WP88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

266748:EL218 RS13945
gene id: 266748:EL218_RS13945
uniprot id: A0A3S4V4P9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

266748:EL218 RS12945
gene id: 266748:EL218_RS12945
uniprot id: A0A3S4V4C7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

266748:EL218 RS07005
gene id: 266748:EL218_RS07005
uniprot id: A0A3S5EUS4
names: Cofactor
names: Similarity
messages: Belongs to the 4HPPD family.
messages: Binds 1 Fe cation per subunit.

266748:EL218 RS05630
gene id: 266748:EL218_RS05630
uniprot id: A0A448NQD1
names: Subcellular Location Annotation
messages: Membrane

266748:EL218 RS06300
gene id: 266748:EL218_RS06300
uniprot id: A0A3S4V282
names: Similarity
messages: Belongs to the catalase family.

266748:EL218 RS08895
gene id: 266748:EL218_RS08895
uniprot id: A0A448NS50
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Cell inner membrane
messages: Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.

266748:EL218 RS07135
gene id: 266748:EL218_RS07135
uniprot id: A0A3S5EUS5
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

266748:EL218 RS09085
gene id: 266748:EL218_RS09085
uniprot id: A0A3S4VFG2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

266748:EL218 RS00045
gene id: 266748:EL218_RS00045
uniprot id: A0A448NM45
names: Similarity
messages: Belongs to the SusD family.

266748:EL218 RS07785
gene id: 266748:EL218_RS07785
uniprot id: A0A3S4YK06
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

266748:EL218 RS14285
gene id: 266748:EL218_RS14285
uniprot id: A0A3S4UP85
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

266748:EL218 RS07275
gene id: 266748:EL218_RS07275
uniprot id: A0A3S4W4D3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

266748:EL218 RS04180
gene id: 266748:EL218_RS04180
uniprot id: A0A448NPJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

266748:EL218 RS12855
gene id: 266748:EL218_RS12855
uniprot id: A0A3S4W626
names: Function
names: Similarity
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.

266748:EL218 RS02695
gene id: 266748:EL218_RS02695
uniprot id: A0A3S4UQI2
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

266748:EL218 RS10925
gene id: 266748:EL218_RS10925
uniprot id: A0A3S4YU88
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

266748:EL218 RS08655
gene id: 266748:EL218_RS08655
uniprot id: A0A448NS20
names: Subcellular Location Annotation
messages: Membrane

266748:EL218 RS11920
gene id: 266748:EL218_RS11920
uniprot id: A0A3S4UUQ8
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

266748:EL218 RS01445
gene id: 266748:EL218_RS01445
uniprot id: A0A3S4UYZ9
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

266748:EL218 RS11715
gene id: 266748:EL218_RS11715
uniprot id: A0A3S4UNF9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

266748:EL218 RS01345
gene id: 266748:EL218_RS01345
uniprot id: A0A448NMX0
names: Similarity
messages: Belongs to the SAM hydrolase / SAM-dependent halogenase family.

266748:EL218 RS03220
gene id: 266748:EL218_RS03220
uniprot id: A0A3S4UJT9
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

266748:EL218 RS02510
gene id: 266748:EL218_RS02510
uniprot id: A0A3S4UJE3
names: Similarity
messages: Belongs to the ice-binding protein family.

266748:EL218 RS09215
gene id: 266748:EL218_RS09215
uniprot id: A0A448NSD8
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

266748:EL218 RS09360
gene id: 266748:EL218_RS09360
uniprot id: A0A3S4UMS0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

266748:EL218 RS08220
gene id: 266748:EL218_RS08220
uniprot id: A0A3S4YTD8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

266748:EL218 RS03660
gene id: 266748:EL218_RS03660
uniprot id: A0A448NP58
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

266748:EL218 RS13785
gene id: 266748:EL218_RS13785
uniprot id: A0A3S5EUZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

266748:EL218 RS04285
gene id: 266748:EL218_RS04285
uniprot id: A0A3S4V0R4
names: Similarity
messages: Belongs to the AlaDH/PNT family.

266748:EL218 RS03315
gene id: 266748:EL218_RS03315
uniprot id: A0A3S5EUJ5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

266748:EL218 RS07855
gene id: 266748:EL218_RS07855
uniprot id: A0A448NRP3
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

266748:EL218 RS00840
gene id: 266748:EL218_RS00840
uniprot id: A0A3S4W0L6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

266748:EL218 RS11305
gene id: 266748:EL218_RS11305
uniprot id: A0A3S4W5I5
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

266748:EL218 RS01420
gene id: 266748:EL218_RS01420
uniprot id: A0A3S5EUF4
names: Subcellular Location Annotation
messages: Membrane

266748:EL218 RS00795
gene id: 266748:EL218_RS00795
uniprot id: A0A448NMJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

266748:EL218 RS10535
gene id: 266748:EL218_RS10535
uniprot id: A0A3S4UN46
names: Similarity
messages: Belongs to the LacAB/RpiB family.

266748:EL218 RS09565
gene id: 266748:EL218_RS09565
uniprot id: A0A448NSI1
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

266748:EL218 RS05485
gene id: 266748:EL218_RS05485
uniprot id: A0A3S4WS29
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

266748:EL218 RS09575
gene id: 266748:EL218_RS09575
uniprot id: A0A448NSI6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

266748:EL218 RS09505
gene id: 266748:EL218_RS09505
uniprot id: A0A3S4UTX7
names: Similarity
messages: Belongs to the SUI1 family.

266748:EL218 RS08500
gene id: 266748:EL218_RS08500
uniprot id: A0A3S4YTG7
names: Similarity
messages: Belongs to the Dps family.

266748:EL218 RS11645
gene id: 266748:EL218_RS11645
uniprot id: A0A448NTP7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

266748:EL218 RS00950
gene id: 266748:EL218_RS00950
uniprot id: A0A448NML5
names: Subcellular Location Annotation
messages: Membrane

266748:EL218 RS00750
gene id: 266748:EL218_RS00750
uniprot id: A0A3S4UI86
names: Subcellular Location Annotation
messages: Membrane

266748:EL218 RS06410
gene id: 266748:EL218_RS06410
uniprot id: A0A448NQV2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

266748:EL218 RS08470
gene id: 266748:EL218_RS08470
uniprot id: A0A448NRY6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

266748:EL218 RS08585
gene id: 266748:EL218_RS08585
uniprot id: A0A3S4YTH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

266748:EL218 RS00810
gene id: 266748:EL218_RS00810
uniprot id: A0A448NMK2
names: Similarity
messages: Belongs to the AHA1 family.

266748:EL218 RS04385
gene id: 266748:EL218_RS04385
uniprot id: A0A448NPJ9
names: Caution
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

266748:EL218 RS13450
gene id: 266748:EL218_RS13450
uniprot id: A0A448NUP3
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

266748:EL218 RS00180
gene id: 266748:EL218_RS00180
uniprot id: A0A3S4UHX2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

266748:EL218 RS00135
gene id: 266748:EL218_RS00135
uniprot id: A0A3S4WN39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

266748:EL218 RS11525
gene id: 266748:EL218_RS11525
uniprot id: A0A3S4V3T5
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Binds 1 copper ion per subunit, denoted as copper B.
messages: Binds 2 heme groups per subunit, denoted as high- and low-spin.
messages: Membrane

266748:EL218 RS03770
gene id: 266748:EL218_RS03770
uniprot id: A0A448NPB0
names: Subcellular Location Annotation
messages: Membrane

266748:EL218 RS02165
gene id: 266748:EL218_RS02165
uniprot id: A0A448NND2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

266748:EL218 RS02685
gene id: 266748:EL218_RS02685
uniprot id: A0A3S4VCD1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

266748:EL218 RS09920
gene id: 266748:EL218_RS09920
uniprot id: A0A448NSQ9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

266748:EL218 RS03635
gene id: 266748:EL218_RS03635
uniprot id: A0A3S4UWD0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.
messages: Ca(+)/H(+) antiporter that extrudes calcium in exchange for external protons.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

266748:EL218 RS04205
gene id: 266748:EL218_RS04205
uniprot id: A0A3S4V0P8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Membrane

266748:EL218 RS11110
gene id: 266748:EL218_RS11110
uniprot id: A0A448NTG2
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

266748:EL218 RS06495
gene id: 266748:EL218_RS06495
uniprot id: A0A3S4W467
names: Similarity
messages: Belongs to the asparaginase 1 family.

266748:EL218 RS07325
gene id: 266748:EL218_RS07325
uniprot id: A0A448NRA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAL/histidase family.
messages: Cytoplasm

266748:EL218 RS12335
gene id: 266748:EL218_RS12335
uniprot id: A0A3S5EUY2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

266748:EL218 RS11155
gene id: 266748:EL218_RS11155
uniprot id: A0A3S4UNA0
names: Similarity
messages: Belongs to the RNA polymerase subunit omega family.

266748:EL218 RS10725
gene id: 266748:EL218_RS10725
uniprot id: A0A3S4YU64
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

266748:EL218 RS12980
gene id: 266748:EL218_RS12980
uniprot id: A0A3S4YUW2
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

266748:EL218 RS08855
gene id: 266748:EL218_RS08855
uniprot id: A0A448NS34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

266748:EL218 RS01250
gene id: 266748:EL218_RS01250
uniprot id: A0A3S5EUF0
names: Similarity
messages: Belongs to the SAICAR synthetase family.

266748:EL218 RS06060
gene id: 266748:EL218_RS06060
uniprot id: A0A448NQN6
names: Similarity
messages: Belongs to the DEAD box helicase family.

266748:EL218 RS01025
gene id: 266748:EL218_RS01025
uniprot id: A0A3S4YG10
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

266748:EL218 RS10415
gene id: 266748:EL218_RS10415
uniprot id: A0A3S4UZ90
names: Similarity
messages: Belongs to the phosphohexose mutase family.

266748:EL218 RS08460
gene id: 266748:EL218_RS08460
uniprot id: A0A448NS44
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

266748:EL218 RS13920
gene id: 266748:EL218_RS13920
uniprot id: A0A448NUZ4
names: Similarity
messages: Belongs to the nitroreductase family.

266748:EL218 RS06380
gene id: 266748:EL218_RS06380
uniprot id: A0A3S4W457
names: Subcellular Location Annotation
messages: Membrane

266748:EL218 RS09665
gene id: 266748:EL218_RS09665
uniprot id: A0A448NSK2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

266748:EL218 RS13190
gene id: 266748:EL218_RS13190
uniprot id: A0A3S4UV97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane