265072:MFLA RS00755
gene id: 265072:MFLA_RS00755
uniprot id: Q1H522
names: Caution
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HPrK/P family.
messages: Both phosphorylation and phosphorolysis are carried out by the same active site and suggest a common mechanism for both reactions.
messages: Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr).
messages: Homohexamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The Walker A ATP-binding motif also binds Pi and PPi.

265072:MFLA RS07985
gene id: 265072:MFLA_RS07985
uniprot id: Q1H112
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

265072:MFLA RS09795
gene id: 265072:MFLA_RS09795
uniprot id: Q1H003
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.

265072:MFLA RS10080
gene id: 265072:MFLA_RS10080
uniprot id: Q1GZU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliJ family.
messages: Cell membrane
messages: Membrane

265072:MFLA RS09950
gene id: 265072:MFLA_RS09950
uniprot id: Q1GZX2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sigma-70 factor family. FliA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes.

265072:MFLA RS02345
gene id: 265072:MFLA_RS02345
uniprot id: Q1H461
names: Similarity
messages: Belongs to the glutamine synthetase family.

265072:MFLA RS00385
gene id: 265072:MFLA_RS00385
uniprot id: Q1GXE6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

265072:MFLA RS07710
gene id: 265072:MFLA_RS07710
uniprot id: Q1H165
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

265072:MFLA RS10320
gene id: 265072:MFLA_RS10320
uniprot id: Q1GZP9
names: Subcellular Location Annotation
messages: Membrane

265072:MFLA RS09135
gene id: 265072:MFLA_RS09135
uniprot id: Q1H0D3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Cell inner membrane
messages: Homoheptamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.

265072:MFLA RS08480
gene id: 265072:MFLA_RS08480
uniprot id: Q1H0R4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transaldolase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

265072:MFLA RS00370
gene id: 265072:MFLA_RS00370
uniprot id: Q1GXD3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

265072:MFLA RS03125
gene id: 265072:MFLA_RS03125
uniprot id: Q1H3Q7
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

265072:MFLA RS12490
gene id: 265072:MFLA_RS12490
uniprot id: Q1GYH5
names: Similarity
messages: Belongs to the glutamine synthetase family.

265072:MFLA RS10045
gene id: 265072:MFLA_RS10045
uniprot id: Q1GZV3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

265072:MFLA RS10500
gene id: 265072:MFLA_RS10500
uniprot id: Q1GZL3
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

265072:MFLA RS03075
gene id: 265072:MFLA_RS03075
uniprot id: Q1H3R7
names: Function
names: Similarity
messages: Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control.
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

265072:MFLA RS03940
gene id: 265072:MFLA_RS03940
uniprot id: Q1H398
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily.
messages: Binds 1 NADP(+) per subunit.
messages: Catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose.
messages: Contains a large N-terminal NADP-binding domain, and a smaller C-terminal substrate-binding domain.
messages: Homopentamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

265072:MFLA RS11805
gene id: 265072:MFLA_RS11805
uniprot id: Q1GYV9
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

265072:MFLA RS05000
gene id: 265072:MFLA_RS05000
uniprot id: Q1H2P4
names: Function
names: Similarity
messages: Belongs to the phage GPA family.
messages: Possible endonuclease which induces a single-strand cut and initiates DNA replication.

265072:MFLA RS05170
gene id: 265072:MFLA_RS05170
uniprot id: Q1H2L0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the lipid A palmitoyltransferase family.
messages: Cell outer membrane
messages: Homodimer.
messages: Transfers a fatty acid residue from the sn-1 position of a phospholipid to the N-linked hydroxyfatty acid chain on the proximal unit of lipid A or its precursors.

265072:MFLA RS08580
gene id: 265072:MFLA_RS08580
uniprot id: Q1H0P4
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

265072:MFLA RS01480
gene id: 265072:MFLA_RS01480
uniprot id: Q1H4N2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity).

265072:MFLA RS03690
gene id: 265072:MFLA_RS03690
uniprot id: Q1H3E9
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
messages: In the C-terminal section; belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

265072:MFLA RS01775
gene id: 265072:MFLA_RS01775
uniprot id: Q1H4H1
names: Subcellular Location Annotation
messages: Membrane

265072:MFLA RS08950
gene id: 265072:MFLA_RS08950
uniprot id: Q1H0H1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

265072:MFLA RS13415
gene id: 265072:MFLA_RS13415
uniprot id: Q1GXZ0
names: Similarity
messages: Belongs to the DODA-type extradiol aromatic ring-opening dioxygenase family.

265072:MFLA RS10220
gene id: 265072:MFLA_RS10220
uniprot id: Q1GZR9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

265072:MFLA RS06305
gene id: 265072:MFLA_RS06305
uniprot id: Q1H1Y7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DksA family.
messages: Cytoplasm
messages: Interacts directly with the RNA polymerase.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters.

265072:MFLA RS12505
gene id: 265072:MFLA_RS12505
uniprot id: Q1GYH2
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes.

265072:MFLA RS08605
gene id: 265072:MFLA_RS08605
uniprot id: Q1H0N9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. PqqE family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the cross-linking of a glutamate residue and a tyrosine residue in the PqqA protein as part of the biosynthesis of pyrroloquinoline quinone (PQQ).
messages: Interacts with PqqD. The interaction is necessary for activity of PqqE.

265072:MFLA RS12070
gene id: 265072:MFLA_RS12070
uniprot id: Q1GYQ7
names: Similarity
messages: Belongs to the UPF0047 family.

265072:MFLA RS04705
gene id: 265072:MFLA_RS04705
uniprot id: Q1H2F7
names: Similarity
messages: Belongs to the 6-phosphogluconate dehydrogenase family.

265072:MFLA RS09775
gene id: 265072:MFLA_RS09775
uniprot id: Q1H007
names: Function
names: Similarity
messages: Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).

265072:MFLA RS05500
gene id: 265072:MFLA_RS05500
uniprot id: Q1H2E4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the R-transferase family. Bpt subfamily.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate.

265072:MFLA RS05770
gene id: 265072:MFLA_RS05770
uniprot id: Q1H291
names: Function
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.
messages: DNA-dependent ATPase that plays important roles in cellular responses to stalled DNA replication processes.

265072:MFLA RS12715
gene id: 265072:MFLA_RS12715
uniprot id: Q1GYD0
names: Function
names: Similarity
messages: Belongs to the MreC family.
messages: Involved in formation and maintenance of cell shape.

265072:MFLA RS06810
gene id: 265072:MFLA_RS06810
uniprot id: Q1H1N7
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

265072:MFLA RS11300
gene id: 265072:MFLA_RS11300
uniprot id: Q1GZ60
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell inner membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Membrane

265072:MFLA RS07815
gene id: 265072:MFLA_RS07815
uniprot id: Q1H144
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

265072:MFLA RS01535
gene id: 265072:MFLA_RS01535
uniprot id: Q1H4M1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

265072:MFLA RS12135
gene id: 265072:MFLA_RS12135
uniprot id: Q1GYP5
names: Function
names: Similarity
messages: Belongs to the catalase family. HPII subfamily.
messages: Serves to protect cells from the toxic effects of hydrogen peroxide.

265072:MFLA RS03035
gene id: 265072:MFLA_RS03035
uniprot id: Q1H3S5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

265072:MFLA RS10110
gene id: 265072:MFLA_RS10110
uniprot id: Q1GZU0
names: Similarity
messages: Belongs to the type III secretion exporter family.

265072:MFLA RS01920
gene id: 265072:MFLA_RS01920
uniprot id: Q1H4E3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

265072:MFLA RS12350
gene id: 265072:MFLA_RS12350
uniprot id: Q1GYK3
names: Similarity
messages: Belongs to the GSP E family.

265072:MFLA RS01390
gene id: 265072:MFLA_RS01390
uniprot id: Q1H4Q0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

265072:MFLA RS11945
gene id: 265072:MFLA_RS11945
uniprot id: Q1GYT2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Pal lipoprotein family.
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

265072:MFLA RS01565
gene id: 265072:MFLA_RS01565
uniprot id: Q1H4L4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

265072:MFLA RS11830
gene id: 265072:MFLA_RS11830
uniprot id: Q1GYV4
names: Subcellular Location Annotation
messages: Membrane

265072:MFLA RS12625
gene id: 265072:MFLA_RS12625
uniprot id: Q1GYE8
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

265072:MFLA RS07160
gene id: 265072:MFLA_RS07160
uniprot id: Q1H1H0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

265072:MFLA RS10835
gene id: 265072:MFLA_RS10835
uniprot id: Q1GZF3
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

265072:MFLA RS09550
gene id: 265072:MFLA_RS09550
uniprot id: Q1H052
names: Similarity
messages: Belongs to the ArsC family.

265072:MFLA RS07915
gene id: 265072:MFLA_RS07915
uniprot id: Q1H125
names: Similarity
messages: Belongs to the NtaA/SnaA/DszA monooxygenase family.

265072:MFLA RS08735
gene id: 265072:MFLA_RS08735
uniprot id: Q1H0L3
names: Similarity
messages: Belongs to the UPF0234 family.

265072:MFLA RS13060
gene id: 265072:MFLA_RS13060
uniprot id: Q1GY60
names: Similarity
messages: Belongs to the glutamine synthetase family.

265072:MFLA RS05370
gene id: 265072:MFLA_RS05370
uniprot id: Q1H2H0
names: Similarity
messages: Belongs to the threonine synthase family.

265072:MFLA RS07790
gene id: 265072:MFLA_RS07790
uniprot id: Q1H149
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

265072:MFLA RS11560
gene id: 265072:MFLA_RS11560
uniprot id: Q1GZ07
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

265072:MFLA RS02965
gene id: 265072:MFLA_RS02965
uniprot id: Q1H3T9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

265072:MFLA RS01170
gene id: 265072:MFLA_RS01170
uniprot id: Q1H4T9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

265072:MFLA RS10690
gene id: 265072:MFLA_RS10690
uniprot id: Q1GZI2
names: Similarity
messages: Belongs to the UPF0434 family.

265072:MFLA RS05365
gene id: 265072:MFLA_RS05365
uniprot id: Q1H2H1
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

265072:MFLA RS09165
gene id: 265072:MFLA_RS09165
uniprot id: Q1H0C7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

265072:MFLA RS09490
gene id: 265072:MFLA_RS09490
uniprot id: Q1H064
names: Similarity
messages: Belongs to the glutamine synthetase family.

265072:MFLA RS06470
gene id: 265072:MFLA_RS06470
uniprot id: Q1H1V5
names: Similarity
messages: Belongs to the peptidase S16 family.

265072:MFLA RS05460
gene id: 265072:MFLA_RS05460
uniprot id: Q1H2F2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the OMP decarboxylase family. Type 1 subfamily.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
messages: Homodimer.

265072:MFLA RS08320
gene id: 265072:MFLA_RS08320
uniprot id: Q1H0U5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

265072:MFLA RS10685
gene id: 265072:MFLA_RS10685
uniprot id: Q1GZI3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
messages: Belongs to the KdsB family.
messages: Cytoplasm

265072:MFLA RS11275
gene id: 265072:MFLA_RS11275
uniprot id: Q1GZ65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

265072:MFLA RS05605
gene id: 265072:MFLA_RS05605
uniprot id: Q1H2C3
names: Similarity
messages: Belongs to the UPF0178 family.

265072:MFLA RS12270
gene id: 265072:MFLA_RS12270
uniprot id: Q1GYL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

265072:MFLA RS06795
gene id: 265072:MFLA_RS06795
uniprot id: Q1H1P0
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

265072:MFLA RS05425
gene id: 265072:MFLA_RS05425
uniprot id: Q1H2F9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Catalyzes the deamination of dCTP to dUTP.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

265072:MFLA RS00090
gene id: 265072:MFLA_RS00090
uniprot id: Q1GX83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

265072:MFLA RS05825
gene id: 265072:MFLA_RS05825
uniprot id: Q1H281
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

265072:MFLA RS01195
gene id: 265072:MFLA_RS01195
uniprot id: Q1H4T4
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

265072:MFLA RS01140
gene id: 265072:MFLA_RS01140
uniprot id: Q1H4U5
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

265072:MFLA RS09650
gene id: 265072:MFLA_RS09650
uniprot id: Q1H032
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

265072:MFLA RS10700
gene id: 265072:MFLA_RS10700
uniprot id: Q1GZI0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Lipid exporter (TC 3.A.1.106) family.
messages: Cell inner membrane
messages: Homodimer.
messages: In MsbA the ATP-binding domain (NBD) and the transmembrane domain (TMD) are fused.
messages: Involved in lipopolysaccharide (LPS) biosynthesis. Translocates lipid A-core from the inner to the outer leaflet of the inner membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation.

265072:MFLA RS12805
gene id: 265072:MFLA_RS12805
uniprot id: Q1GYB2
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

265072:MFLA RS01420
gene id: 265072:MFLA_RS01420
uniprot id: Q1H4P4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

265072:MFLA RS06420
gene id: 265072:MFLA_RS06420
uniprot id: Q1H1W4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Homodimer.
messages: Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate.

265072:MFLA RS07315
gene id: 265072:MFLA_RS07315
uniprot id: Q1H1E0
names: Similarity
messages: Belongs to the CopC family.

265072:MFLA RS02935
gene id: 265072:MFLA_RS02935
uniprot id: Q1H3U5
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG).

265072:MFLA RS02770
gene id: 265072:MFLA_RS02770
uniprot id: Q1H3X8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

265072:MFLA RS04085
gene id: 265072:MFLA_RS04085
uniprot id: Q1H370
names: Subcellular Location Annotation
messages: Membrane

265072:MFLA RS06755
gene id: 265072:MFLA_RS06755
uniprot id: Q1H1P8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase E/G family. RNase E subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per homotetramer.
messages: Cell inner membrane
messages: Cytoplasm
messages: Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs.
messages: Homotetramer formed by a dimer of dimers.

265072:MFLA RS09520
gene id: 265072:MFLA_RS09520
uniprot id: Q1H058
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsbB family.
messages: Cell inner membrane
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein.

265072:MFLA RS10250
gene id: 265072:MFLA_RS10250
uniprot id: Q1GZR3
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

265072:MFLA RS08235
gene id: 265072:MFLA_RS08235
uniprot id: Q1H0W3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

265072:MFLA RS04640
gene id: 265072:MFLA_RS04640
uniprot id: Q1H2H0
names: Similarity
messages: Belongs to the threonine synthase family.

265072:MFLA RS06120
gene id: 265072:MFLA_RS06120
uniprot id: Q1H223
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

265072:MFLA RS01500
gene id: 265072:MFLA_RS01500
uniprot id: Q1H4M8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

265072:MFLA RS03785
gene id: 265072:MFLA_RS03785
uniprot id: Q1H3D0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the glyoxalase I family.
messages: Binds 1 nickel ion per subunit.
messages: Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione.

265072:MFLA RS00275
gene id: 265072:MFLA_RS00275
uniprot id: Q1GXC2
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

265072:MFLA RS04370
gene id: 265072:MFLA_RS04370
uniprot id: Q1H2M4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

265072:MFLA RS02490
gene id: 265072:MFLA_RS02490
uniprot id: Q1H429
names: Function
messages: Member of the two-component regulatory system PhoR/PhoB involved in the phosphate regulon genes expression. PhoR may function as a membrane-associated protein kinase that phosphorylates PhoB in response to environmental signals.

265072:MFLA RS08315
gene id: 265072:MFLA_RS08315
uniprot id: Q1H0U6
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.

265072:MFLA RS03730
gene id: 265072:MFLA_RS03730
uniprot id: Q1H3E1
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

265072:MFLA RS09570
gene id: 265072:MFLA_RS09570
uniprot id: Q1H048
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

265072:MFLA RS03685
gene id: 265072:MFLA_RS03685
uniprot id: Q1H3F0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhD family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.

265072:MFLA RS09975
gene id: 265072:MFLA_RS09975
uniprot id: Q1GZW7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FlgA family.
messages: Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly.
messages: Periplasm

265072:MFLA RS14040
gene id: 265072:MFLA_RS14040
uniprot id: Q1GXM4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase A chain family.
messages: Cell inner membrane
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

265072:MFLA RS06490
gene id: 265072:MFLA_RS06490
uniprot id: Q1H1V1
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 2 family.

265072:MFLA RS04480
gene id: 265072:MFLA_RS04480
uniprot id: Q1H2K2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 90 family.
messages: Cytoplasm
messages: Homodimer.
messages: Molecular chaperone. Has ATPase activity.

265072:MFLA RS01630
gene id: 265072:MFLA_RS01630
uniprot id: Q1H4K1
names: Similarity
messages: Belongs to the UPF0758 family.

265072:MFLA RS07735
gene id: 265072:MFLA_RS07735
uniprot id: Q1H160
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

265072:MFLA RS07090
gene id: 265072:MFLA_RS07090
uniprot id: Q1H1I2
names: Similarity
messages: Belongs to the GSP E family.

265072:MFLA RS10455
gene id: 265072:MFLA_RS10455
uniprot id: Q1GZM2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell inner membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

265072:MFLA RS01585
gene id: 265072:MFLA_RS01585
uniprot id: Q1H4L0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

265072:MFLA RS08725
gene id: 265072:MFLA_RS08725
uniprot id: Q1H0L5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

265072:MFLA RS14145
gene id: 265072:MFLA_RS14145
uniprot id: Q1GZU7
names: Function
names: Similarity
messages: Belongs to the FliK family.
messages: Controls the length of the flagellar hook.

265072:MFLA RS10015
gene id: 265072:MFLA_RS10015
uniprot id: Q1GZV9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgI family.
messages: Periplasm
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

265072:MFLA RS10515
gene id: 265072:MFLA_RS10515
uniprot id: Q1GZL0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity).

265072:MFLA RS00300
gene id: 265072:MFLA_RS00300
uniprot id: Q1GXC6
names: Similarity
messages: Belongs to the citrate synthase family.

265072:MFLA RS11810
gene id: 265072:MFLA_RS11810
uniprot id: Q1GYV8
names: PTM
messages: Binds 1 heme c group covalently per subunit.

265072:MFLA RS08685
gene id: 265072:MFLA_RS08685
uniprot id: Q1H0M3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

265072:MFLA RS02860
gene id: 265072:MFLA_RS02860
uniprot id: Q1H3V9
names: Similarity
messages: Belongs to the type IB topoisomerase family.

265072:MFLA RS00950
gene id: 265072:MFLA_RS00950
uniprot id: Q1H4Y4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

265072:MFLA RS10855
gene id: 265072:MFLA_RS10855
uniprot id: Q1GZE9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.

265072:MFLA RS04000
gene id: 265072:MFLA_RS04000
uniprot id: Q1H387
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
messages: Cytoplasm
messages: Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.

265072:MFLA RS07835
gene id: 265072:MFLA_RS07835
uniprot id: Q1H140
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

265072:MFLA RS11630
gene id: 265072:MFLA_RS11630
uniprot id: Q1GYZ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsL family.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
messages: Membrane
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

265072:MFLA RS09440
gene id: 265072:MFLA_RS09440
uniprot id: Q1H074
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.
messages: Cell inner membrane
messages: Involved in the import of queuosine (Q) precursors, required for Q precursor salvage.

265072:MFLA RS11240
gene id: 265072:MFLA_RS11240
uniprot id: Q1GZ72
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK.

265072:MFLA RS05375
gene id: 265072:MFLA_RS05375
uniprot id: Q9RAM7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

265072:MFLA RS10125
gene id: 265072:MFLA_RS10125
uniprot id: Q1GZT7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliS family.
messages: cytosol

265072:MFLA RS10350
gene id: 265072:MFLA_RS10350
uniprot id: Q1GZP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

265072:MFLA RS03465
gene id: 265072:MFLA_RS03465
uniprot id: Q1H3J1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

265072:MFLA RS13650
gene id: 265072:MFLA_RS13650
uniprot id: Q1GXU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

265072:MFLA RS11335
gene id: 265072:MFLA_RS11335
uniprot id: Q1GZ53
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

265072:MFLA RS01465
gene id: 265072:MFLA_RS01465
uniprot id: Q1H4N5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

265072:MFLA RS04455
gene id: 265072:MFLA_RS04455
uniprot id: Q1H2K7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

265072:MFLA RS09315
gene id: 265072:MFLA_RS09315
uniprot id: Q1H099
names: Subcellular Location Annotation
messages: Membrane

265072:MFLA RS13125
gene id: 265072:MFLA_RS13125
uniprot id: Q1GY47
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

265072:MFLA RS09105
gene id: 265072:MFLA_RS09105
uniprot id: Q1H0D8
names: Similarity
messages: Belongs to the peptidase S24 family.

265072:MFLA RS13100
gene id: 265072:MFLA_RS13100
uniprot id: Q1GY52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LysR transcriptional regulatory family.
messages: Cytoplasm

265072:MFLA RS13010
gene id: 265072:MFLA_RS13010
uniprot id: Q1GY70
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

265072:MFLA RS09250
gene id: 265072:MFLA_RS09250
uniprot id: Q1H0B3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RlmJ family.
messages: Monomer.
messages: Specifically methylates the adenine in position 2030 of 23S rRNA.

265072:MFLA RS05555
gene id: 265072:MFLA_RS05555
uniprot id: Q1H2D3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

265072:MFLA RS02545
gene id: 265072:MFLA_RS02545
uniprot id: Q1H419
names: Similarity
messages: Belongs to the YkuD family.

265072:MFLA RS07780
gene id: 265072:MFLA_RS07780
uniprot id: Q1H151
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
messages: Cytoplasm
messages: Homotrimer.
messages: Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

265072:MFLA RS09500
gene id: 265072:MFLA_RS09500
uniprot id: Q1H062
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

265072:MFLA RS07215
gene id: 265072:MFLA_RS07215
uniprot id: Q1H1F9
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

265072:MFLA RS00645
gene id: 265072:MFLA_RS00645
uniprot id: Q1GXJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

265072:MFLA RS01450
gene id: 265072:MFLA_RS01450
uniprot id: Q1H4N8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

265072:MFLA RS00485
gene id: 265072:MFLA_RS00485
uniprot id: Q1GXF7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

265072:MFLA RS09790
gene id: 265072:MFLA_RS09790
uniprot id: Q1H004
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

265072:MFLA RS10485
gene id: 265072:MFLA_RS10485
uniprot id: Q1GZL6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

265072:MFLA RS13025
gene id: 265072:MFLA_RS13025
uniprot id: Q1GY68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0060 family.
messages: Cell inner membrane

265072:MFLA RS03170
gene id: 265072:MFLA_RS03170
uniprot id: Q1H3P7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic sulfate-binding protein family.
messages: Periplasm

265072:MFLA RS03020
gene id: 265072:MFLA_RS03020
uniprot id: Q1H3S8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

265072:MFLA RS09670
gene id: 265072:MFLA_RS09670
uniprot id: Q1H028
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

265072:MFLA RS07825
gene id: 265072:MFLA_RS07825
uniprot id: Q1H142
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

265072:MFLA RS05980
gene id: 265072:MFLA_RS05980
uniprot id: Q1H248
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

265072:MFLA RS03620
gene id: 265072:MFLA_RS03620
uniprot id: Q1H3G2
names: Subcellular Location Annotation
messages: Membrane

265072:MFLA RS12010
gene id: 265072:MFLA_RS12010
uniprot id: Q1GYR9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

265072:MFLA RS07170
gene id: 265072:MFLA_RS07170
uniprot id: Q1H1G8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

265072:MFLA RS11175
gene id: 265072:MFLA_RS11175
uniprot id: Q1GZ84
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.

265072:MFLA RS11590
gene id: 265072:MFLA_RS11590
uniprot id: Q1GZ01
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell inner membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).

265072:MFLA RS01755
gene id: 265072:MFLA_RS01755
uniprot id: Q1H4H5
names: Similarity
messages: Belongs to the glucose-6-phosphate 1-epimerase family.

265072:MFLA RS09050
gene id: 265072:MFLA_RS09050
uniprot id: Q1H0F1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease beta subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

265072:MFLA RS03605
gene id: 265072:MFLA_RS03605
uniprot id: Q1H3G5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

265072:MFLA RS12620
gene id: 265072:MFLA_RS12620
uniprot id: Q1GYE9
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

265072:MFLA RS13615
gene id: 265072:MFLA_RS13615
uniprot id: Q1GXV2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

265072:MFLA RS10800
gene id: 265072:MFLA_RS10800
uniprot id: Q1GZG0
names: Similarity
messages: Belongs to the YggT family.

265072:MFLA RS08390
gene id: 265072:MFLA_RS08390
uniprot id: Q1H0T1
names: Subcellular Location Annotation
messages: Membrane

265072:MFLA RS11940
gene id: 265072:MFLA_RS11940
uniprot id: Q1GYT3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CpoB family.
messages: Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division.
messages: Periplasm

265072:MFLA RS03500
gene id: 265072:MFLA_RS03500
uniprot id: Q1H3I6
names: Subcellular Location Annotation
messages: Membrane

265072:MFLA RS11385
gene id: 265072:MFLA_RS11385
uniprot id: Q1GZ43
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ZapD family.
messages: Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity.
messages: Cytoplasm
messages: Interacts with FtsZ.

265072:MFLA RS02915
gene id: 265072:MFLA_RS02915
uniprot id: Q1H3U9
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

265072:MFLA RS11020
gene id: 265072:MFLA_RS11020
uniprot id: Q1GZB6
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

265072:MFLA RS02685
gene id: 265072:MFLA_RS02685
uniprot id: Q1H3Z2
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

265072:MFLA RS01740
gene id: 265072:MFLA_RS01740
uniprot id: Q1H4H8
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

265072:MFLA RS00015
gene id: 265072:MFLA_RS00015
uniprot id: Q1GXJ9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

265072:MFLA RS07675
gene id: 265072:MFLA_RS07675
uniprot id: Q1H172
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.

265072:MFLA RS12275
gene id: 265072:MFLA_RS12275
uniprot id: Q1GYL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

265072:MFLA RS10710
gene id: 265072:MFLA_RS10710
uniprot id: Q1GZH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

265072:MFLA RS09080
gene id: 265072:MFLA_RS09080
uniprot id: Q1H0E5
names: Subcellular Location Annotation
messages: Membrane

265072:MFLA RS08640
gene id: 265072:MFLA_RS08640
uniprot id: Q1H0N2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

265072:MFLA RS01445
gene id: 265072:MFLA_RS01445
uniprot id: Q1H4N9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

265072:MFLA RS03225
gene id: 265072:MFLA_RS03225
uniprot id: Q1H3N5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CcoP / FixP family.
messages: Binds 2 heme C groups per subunit.
messages: C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex.
messages: Cell inner membrane
messages: Component of the cbb3-type cytochrome c oxidase.

265072:MFLA RS04015
gene id: 265072:MFLA_RS04015
uniprot id: Q1H384
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

265072:MFLA RS02795
gene id: 265072:MFLA_RS02795
uniprot id: Q1H3X3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

265072:MFLA RS10820
gene id: 265072:MFLA_RS10820
uniprot id: Q1GZF6
names: Similarity
names: Subunit
messages: Belongs to the Nudix hydrolase family. NudJ subfamily.
messages: Monomer.

265072:MFLA RS02825
gene id: 265072:MFLA_RS02825
uniprot id: Q50416
names: Function
names: Subcellular Location Annotation
messages: May be specifically involved in the processing, transport, and/or maturation of the MADH beta-subunit.
messages: Membrane

265072:MFLA RS12205
gene id: 265072:MFLA_RS12205
uniprot id: Q1GYN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

265072:MFLA RS01455
gene id: 265072:MFLA_RS01455
uniprot id: Q1H4N7
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: Methylated by PrmB.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

265072:MFLA RS01280
gene id: 265072:MFLA_RS01280
uniprot id: Q1H4R7
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

265072:MFLA RS09935
gene id: 265072:MFLA_RS09935
uniprot id: Q1GZX5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

265072:MFLA RS13410
gene id: 265072:MFLA_RS13410
uniprot id: Q1GXZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

265072:MFLA RS01530
gene id: 265072:MFLA_RS01530
uniprot id: Q1H4M2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

265072:MFLA RS01250
gene id: 265072:MFLA_RS01250
uniprot id: Q1H4S3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

265072:MFLA RS12615
gene id: 265072:MFLA_RS12615
uniprot id: Q1GYF0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

265072:MFLA RS01795
gene id: 265072:MFLA_RS01795
uniprot id: Q1H4G7
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

265072:MFLA RS02290
gene id: 265072:MFLA_RS02290
uniprot id: Q1H471
names: Subcellular Location Annotation
messages: Membrane

265072:MFLA RS08295
gene id: 265072:MFLA_RS08295
uniprot id: Q1H0V0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

265072:MFLA RS08095
gene id: 265072:MFLA_RS08095
uniprot id: Q1H0Z0
names: Function
messages: Catalyzes the formation of 4-(hydroxymethyl)-2-furancarboxaldehyde phosphate (4-HFC-P) from two molecules of glyceraldehyde-3-P (GA-3-P).

265072:MFLA RS09425
gene id: 265072:MFLA_RS09425
uniprot id: Q1H077
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

265072:MFLA RS04420
gene id: 265072:MFLA_RS04420
uniprot id: Q1H2L4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

265072:MFLA RS06680
gene id: 265072:MFLA_RS06680
uniprot id: Q1H1R3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

265072:MFLA RS07660
gene id: 265072:MFLA_RS07660
uniprot id: Q1H175
names: Similarity
messages: Belongs to the site-specific recombinase resolvase family.

265072:MFLA RS03735
gene id: 265072:MFLA_RS03735
uniprot id: Q1H3E0
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

265072:MFLA RS09435
gene id: 265072:MFLA_RS09435
uniprot id: Q1H075
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 3 family. NagZ subfamily.
messages: Cytoplasm
messages: Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides.

265072:MFLA RS11515
gene id: 265072:MFLA_RS11515
uniprot id: Q1GZ15
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

265072:MFLA RS11510
gene id: 265072:MFLA_RS11510
uniprot id: Q1GZ16
names: Similarity
messages: Belongs to the formate--tetrahydrofolate ligase family.

265072:MFLA RS09640
gene id: 265072:MFLA_RS09640
uniprot id: Q1H034
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

265072:MFLA RS11345
gene id: 265072:MFLA_RS11345
uniprot id: Q1GZ51
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

265072:MFLA RS00775
gene id: 265072:MFLA_RS00775
uniprot id: Q1H518
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

265072:MFLA RS08740
gene id: 265072:MFLA_RS08740
uniprot id: Q1H0L2
names: Function
names: Similarity
messages: Belongs to the nucleoside phosphorylase PpnP family.
messages: Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions.

265072:MFLA RS05750
gene id: 265072:MFLA_RS05750
uniprot id: Q1H295
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Essential cell division protein that coordinates cell division and chromosome segregation. The N-terminus is involved in assembly of the cell-division machinery. The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the dif recombination site, which is located within the replication terminus region. Translocation stops specifically at Xer-dif sites, where FtsK interacts with the Xer recombinase, allowing activation of chromosome unlinking by recombination. FtsK orienting polar sequences (KOPS) guide the direction of DNA translocation. FtsK can remove proteins from DNA as it translocates, but translocation stops specifically at XerCD-dif site, thereby preventing removal of XerC and XerD from dif.
messages: Homohexamer. Forms a ring that surrounds DNA.
messages: Membrane

265072:MFLA RS11340
gene id: 265072:MFLA_RS11340
uniprot id: Q1GZ52
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

265072:MFLA RS12935
gene id: 265072:MFLA_RS12935
uniprot id: Q1GY86
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Cell inner membrane
messages: Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.

265072:MFLA RS10750
gene id: 265072:MFLA_RS10750
uniprot id: Q1GZH0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF nuclease family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

265072:MFLA RS13015
gene id: 265072:MFLA_RS13015
uniprot id: Q1GY69
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

265072:MFLA RS09535
gene id: 265072:MFLA_RS09535
uniprot id: Q1H055
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

265072:MFLA RS05560
gene id: 265072:MFLA_RS05560
uniprot id: Q1H2D2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell inner membrane
messages: Membrane

265072:MFLA RS10270
gene id: 265072:MFLA_RS10270
uniprot id: Q1GZQ9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

265072:MFLA RS07140
gene id: 265072:MFLA_RS07140
uniprot id: Q1H1H2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phospholipase A1 family.
messages: Binds 1 Ca(2+) ion per monomer. In the dimeric form the Ca(2+) is bound by different amino acids with binding of each Ca(2+) shared with ligands coming from each monomer. The Ca(2+) ion may have a role in catalysis.
messages: Cell outer membrane
messages: Homodimer; dimerization is reversible, and the dimeric form is the active one.
messages: Hydrolysis of phosphatidylcholine with phospholipase A2 (EC 3.1.1.4) and phospholipase A1 (EC 3.1.1.32) activities.
messages: Membrane

265072:MFLA RS07320
gene id: 265072:MFLA_RS07320
uniprot id: Q1H1D9
names: Subcellular Location Annotation
messages: Membrane

265072:MFLA RS08995
gene id: 265072:MFLA_RS08995
uniprot id: Q1H0G2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

265072:MFLA RS10725
gene id: 265072:MFLA_RS10725
uniprot id: Q1GZH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

265072:MFLA RS12015
gene id: 265072:MFLA_RS12015
uniprot id: Q1GYR8
names: Similarity
messages: Belongs to the NtaA/SnaA/DszA monooxygenase family.

265072:MFLA RS03480
gene id: 265072:MFLA_RS03480
uniprot id: Q1H3I9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LolB family.
messages: Cell outer membrane
messages: Membrane
messages: Monomer.
messages: Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein.

265072:MFLA RS09410
gene id: 265072:MFLA_RS09410
uniprot id: Q1H080
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

265072:MFLA RS11010
gene id: 265072:MFLA_RS11010
uniprot id: Q1GZB8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

265072:MFLA RS08065
gene id: 265072:MFLA_RS08065
uniprot id: Q1H0Z6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

265072:MFLA RS03245
gene id: 265072:MFLA_RS03245
uniprot id: Q1H3N1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterioferritin family.
messages: Iron-storage protein.
messages: Oligomer of 24 subunits, arranged as 12 dimers, that are packed together to form an approximately spherical molecule with a central cavity, in which large amounts of iron can be deposited.

265072:MFLA RS08695
gene id: 265072:MFLA_RS08695
uniprot id: Q1H0M1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

265072:MFLA RS02865
gene id: 265072:MFLA_RS02865
uniprot id: Q1H3V8
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

265072:MFLA RS07635
gene id: 265072:MFLA_RS07635
uniprot id: Q1H180
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArsB family.
messages: Cell membrane
messages: Involved in arsenical resistance. Thought to form the channel of an arsenite pump.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

265072:MFLA RS01380
gene id: 265072:MFLA_RS01380
uniprot id: Q1H4Q1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

265072:MFLA RS01165
gene id: 265072:MFLA_RS01165
uniprot id: Q1H4U0
names: Similarity
messages: Belongs to the peptidase S11 family.

265072:MFLA RS00010
gene id: 265072:MFLA_RS00010
uniprot id: Q1GXK0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

265072:MFLA RS10255
gene id: 265072:MFLA_RS10255
uniprot id: Q1GZR2
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

265072:MFLA RS10420
gene id: 265072:MFLA_RS10420
uniprot id: Q1GZM9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the methanol dehydrogenase subunit 2 family.
messages: Catalyzes the oxidation of primary alcohols including methanol.
messages: Heterotetramer composed of 2 alpha and 2 beta subunits.

265072:MFLA RS08090
gene id: 265072:MFLA_RS08090
uniprot id: Q1H0Z1
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

265072:MFLA RS14085
gene id: 265072:MFLA_RS14085
uniprot id: Q1GXL4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

265072:MFLA RS10705
gene id: 265072:MFLA_RS10705
uniprot id: Q1GZH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

265072:MFLA RS07050
gene id: 265072:MFLA_RS07050
uniprot id: Q1H1J0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueG family.
messages: Binds 2 [4Fe-4S] clusters per monomer.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

265072:MFLA RS06625
gene id: 265072:MFLA_RS06625
uniprot id: Q1H1S5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Membrane

265072:MFLA RS03515
gene id: 265072:MFLA_RS03515
uniprot id: Q1H3I3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

265072:MFLA RS00690
gene id: 265072:MFLA_RS00690
uniprot id: Q1GXJ3
names: Similarity
messages: Belongs to the GppA/Ppx family.

265072:MFLA RS05255
gene id: 265072:MFLA_RS05255
uniprot id: Q1H2J3
names: Similarity
messages: Belongs to the bleomycin resistance protein family.

265072:MFLA RS01485
gene id: 265072:MFLA_RS01485
uniprot id: Q1H4N1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

265072:MFLA RS11325
gene id: 265072:MFLA_RS11325
uniprot id: Q1GZ55
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

265072:MFLA RS09385
gene id: 265072:MFLA_RS09385
uniprot id: Q1H085
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

265072:MFLA RS06520
gene id: 265072:MFLA_RS06520
uniprot id: Q1H1U5
names: Subcellular Location Annotation
messages: Membrane

265072:MFLA RS10070
gene id: 265072:MFLA_RS10070
uniprot id: Q1GZU8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell inner membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

265072:MFLA RS10055
gene id: 265072:MFLA_RS10055
uniprot id: Q1GZV1
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliO/MopB family.
messages: Cell membrane

265072:MFLA RS06055
gene id: 265072:MFLA_RS06055
uniprot id: Q1H234
names: Similarity
messages: Belongs to the thioredoxin family.

265072:MFLA RS02615
gene id: 265072:MFLA_RS02615
uniprot id: Q1H405
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

265072:MFLA RS02940
gene id: 265072:MFLA_RS02940
uniprot id: Q1H3U4
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

265072:MFLA RS05475
gene id: 265072:MFLA_RS05475
uniprot id: Q1H2E9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

265072:MFLA RS03460
gene id: 265072:MFLA_RS03460
uniprot id: Q1H3J2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

265072:MFLA RS11085
gene id: 265072:MFLA_RS11085
uniprot id: Q1GZA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

265072:MFLA RS05610
gene id: 265072:MFLA_RS05610
uniprot id: Q1H2C2
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

265072:MFLA RS07775
gene id: 265072:MFLA_RS07775
uniprot id: Q1H152
names: Function
names: Similarity
messages: Belongs to the LpxB family.
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

265072:MFLA RS02870
gene id: 265072:MFLA_RS02870
uniprot id: Q1H3V7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

265072:MFLA RS11285
gene id: 265072:MFLA_RS11285
uniprot id: Q1GZ63
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

265072:MFLA RS13270
gene id: 265072:MFLA_RS13270
uniprot id: Q1GY18
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

265072:MFLA RS09120
gene id: 265072:MFLA_RS09120
uniprot id: Q1H0D6
names: Similarity
messages: Belongs to the NtaA/SnaA/DszA monooxygenase family.

265072:MFLA RS04760
gene id: 265072:MFLA_RS04760
uniprot id: Q1H2E6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

265072:MFLA RS05140
gene id: 265072:MFLA_RS05140
uniprot id: Q1H2L6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1C family.
messages: Periplasm

265072:MFLA RS04065
gene id: 265072:MFLA_RS04065
uniprot id: Q1H374
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PstS family.
messages: Involved in the system for phosphate transport across the cytoplasmic membrane.
messages: Periplasm
messages: Secreted

265072:MFLA RS10335
gene id: 265072:MFLA_RS10335
uniprot id: Q1GZP5
names: Subcellular Location Annotation
messages: Membrane

265072:MFLA RS07940
gene id: 265072:MFLA_RS07940
uniprot id: Q1H120
names: Subcellular Location Annotation
messages: Membrane

265072:MFLA RS01625
gene id: 265072:MFLA_RS01625
uniprot id: Q1H4K2
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

265072:MFLA RS11025
gene id: 265072:MFLA_RS11025
uniprot id: Q1GZB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

265072:MFLA RS05935
gene id: 265072:MFLA_RS05935
uniprot id: Q1H258
names: Similarity
messages: Belongs to the thioredoxin family.

265072:MFLA RS10435
gene id: 265072:MFLA_RS10435
uniprot id: Q1GZM6
names: Similarity
messages: Belongs to the bacterial PQQ dehydrogenase family.

265072:MFLA RS11735
gene id: 265072:MFLA_RS11735
uniprot id: Q1GYX3
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

265072:MFLA RS03165
gene id: 265072:MFLA_RS03165
uniprot id: Q1H3P8
names: Similarity
messages: Belongs to the UPF0751 family.

265072:MFLA RS09860
gene id: 265072:MFLA_RS09860
uniprot id: Q1GZZ0
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

265072:MFLA RS11725
gene id: 265072:MFLA_RS11725
uniprot id: Q1GYX5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MobA family.
messages: Cytoplasm
messages: Monomer.
messages: The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.
messages: Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.

265072:MFLA RS05150
gene id: 265072:MFLA_RS05150
uniprot id: Q1H2L4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

265072:MFLA RS00970
gene id: 265072:MFLA_RS00970
uniprot id: Q1H4Y0
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

265072:MFLA RS11825
gene id: 265072:MFLA_RS11825
uniprot id: Q1GYV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S33 family.
messages: Cytoplasm

265072:MFLA RS01005
gene id: 265072:MFLA_RS01005
uniprot id: Q1H4X3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

265072:MFLA RS06160
gene id: 265072:MFLA_RS06160
uniprot id: Q1H215
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.
messages: Cytoplasm
messages: Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity.

265072:MFLA RS10540
gene id: 265072:MFLA_RS10540
uniprot id: Q1GZK6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

265072:MFLA RS03880
gene id: 265072:MFLA_RS03880
uniprot id: Q1H3B1
names: Similarity
messages: Belongs to the NodU/CmcH family.

265072:MFLA RS00255
gene id: 265072:MFLA_RS00255
uniprot id: Q1GXB5
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

265072:MFLA RS12655
gene id: 265072:MFLA_RS12655
uniprot id: Q1GYE2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MetX family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine.

265072:MFLA RS03060
gene id: 265072:MFLA_RS03060
uniprot id: Q1H3S0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

265072:MFLA RS10595
gene id: 265072:MFLA_RS10595
uniprot id: Q1GZJ5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: Forms a 24-polypeptide structural core with octahedral symmetry.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

265072:MFLA RS12475
gene id: 265072:MFLA_RS12475
uniprot id: Q1GYH8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 51 family.
messages: Cell inner membrane
messages: Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors.

265072:MFLA RS03040
gene id: 265072:MFLA_RS03040
uniprot id: Q1H3S4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein L14 (rplN).

265072:MFLA RS01175
gene id: 265072:MFLA_RS01175
uniprot id: Q1H4T8
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TtcA family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is chelated by three Cys residues, the fourth Fe has a free coordination site that may bind a sulfur atom transferred from the persulfide of IscS.
messages: Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.
messages: Cytoplasm
messages: Homodimer.
messages: The thiolation reaction likely consists of two steps: a first activation step by ATP to form an adenylated intermediate of the target base of tRNA, and a second nucleophilic substitution step of the sulfur (S) atom supplied by the hydrosulfide attached to the Fe-S cluster.

265072:MFLA RS02405
gene id: 265072:MFLA_RS02405
uniprot id: Q1H450
names: Function
names: Similarity
messages: Belongs to the Ap4A hydrolase family.
messages: Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP.

265072:MFLA RS07410
gene id: 265072:MFLA_RS07410
uniprot id: Q1H1C2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

265072:MFLA RS02720
gene id: 265072:MFLA_RS02720
uniprot id: Q1H3Y6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

265072:MFLA RS05210
gene id: 265072:MFLA_RS05210
uniprot id: Q1H2K2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 90 family.
messages: Cytoplasm
messages: Homodimer.
messages: Molecular chaperone. Has ATPase activity.

265072:MFLA RS01185
gene id: 265072:MFLA_RS01185
uniprot id: Q1H4T6
names: Subcellular Location Annotation
messages: Mitochondrion

265072:MFLA RS04695
gene id: 265072:MFLA_RS04695
uniprot id: Q1H2F9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Catalyzes the deamination of dCTP to dUTP.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

265072:MFLA RS03320
gene id: 265072:MFLA_RS03320
uniprot id: Q1H3L6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

265072:MFLA RS12760
gene id: 265072:MFLA_RS12760
uniprot id: Q1GYC1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

265072:MFLA RS04790
gene id: 265072:MFLA_RS04790
uniprot id: Q1H2E0
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

265072:MFLA RS09300
gene id: 265072:MFLA_RS09300
uniprot id: Q1H0A3
names: Cofactor
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Binds 1 [4Fe-4S] cluster per subunit.

265072:MFLA RS04530
gene id: 265072:MFLA_RS04530
uniprot id: Q1H2J2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

265072:MFLA RS11460
gene id: 265072:MFLA_RS11460
uniprot id: Q1GZ27
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.
messages: One is catalytic and the other provides a structural contribution.

265072:MFLA RS04890
gene id: 265072:MFLA_RS04890
uniprot id: Q1H2C0
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

265072:MFLA RS13305
gene id: 265072:MFLA_RS13305
uniprot id: Q1GY11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

265072:MFLA RS04905
gene id: 265072:MFLA_RS04905
uniprot id: Q1H2B7
names: Similarity
messages: Belongs to the YjdM family.

265072:MFLA RS05880
gene id: 265072:MFLA_RS05880
uniprot id: Q1H270
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

265072:MFLA RS10795
gene id: 265072:MFLA_RS10795
uniprot id: Q1GZG1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

265072:MFLA RS05310
gene id: 265072:MFLA_RS05310
uniprot id: Q1H2I2
names: Similarity
messages: Belongs to the XFP family.

265072:MFLA RS07690
gene id: 265072:MFLA_RS07690
uniprot id: Q1H169
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

265072:MFLA RS10780
gene id: 265072:MFLA_RS10780
uniprot id: Q1GZG4
names: Similarity
messages: Belongs to the GSP E family.

265072:MFLA RS03280
gene id: 265072:MFLA_RS03280
uniprot id: Q1H3M4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gmhB family.
messages: Cytoplasm

265072:MFLA RS03325
gene id: 265072:MFLA_RS03325
uniprot id: Q1H3L5
names: Function
names: Similarity
messages: In the C-terminal section; belongs to the precorrin methyltransferase family.
messages: In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family.
messages: Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme.

265072:MFLA RS01205
gene id: 265072:MFLA_RS01205
uniprot id: Q1H4T2
names: Subcellular Location Annotation
messages: Membrane

265072:MFLA RS03975
gene id: 265072:MFLA_RS03975
uniprot id: Q1H391
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

265072:MFLA RS04525
gene id: 265072:MFLA_RS04525
uniprot id: Q1H2J3
names: Similarity
messages: Belongs to the bleomycin resistance protein family.

265072:MFLA RS07820
gene id: 265072:MFLA_RS07820
uniprot id: Q1H143
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

265072:MFLA RS09930
gene id: 265072:MFLA_RS09930
uniprot id: Q1GZX6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type III secretion exporter family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

265072:MFLA RS11585
gene id: 265072:MFLA_RS11585
uniprot id: Q1GZ02
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

265072:MFLA RS10475
gene id: 265072:MFLA_RS10475
uniprot id: Q1GZL8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

265072:MFLA RS10815
gene id: 265072:MFLA_RS10815
uniprot id: Q1GZF7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

265072:MFLA RS10465
gene id: 265072:MFLA_RS10465
uniprot id: Q1GZM0
names: Subcellular Location Annotation
messages: Membrane

265072:MFLA RS10620
gene id: 265072:MFLA_RS10620
uniprot id: Q1GZJ0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

265072:MFLA RS03710
gene id: 265072:MFLA_RS03710
uniprot id: Q1H3E5
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

265072:MFLA RS03980
gene id: 265072:MFLA_RS03980
uniprot id: Q1H390
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

265072:MFLA RS03210
gene id: 265072:MFLA_RS03210
uniprot id: Q1H3N9
names: Similarity
messages: Belongs to the SCO1/2 family.

265072:MFLA RS09465
gene id: 265072:MFLA_RS09465
uniprot id: Q1H069
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily.
messages: Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA.

265072:MFLA RS03840
gene id: 265072:MFLA_RS03840
uniprot id: Q1H3B9
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

265072:MFLA RS01575
gene id: 265072:MFLA_RS01575
uniprot id: Q1H4L2
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

265072:MFLA RS08800
gene id: 265072:MFLA_RS08800
uniprot id: Q1H0K2
names: Similarity
messages: Belongs to the bacterial PQQ dehydrogenase family.

265072:MFLA RS02495
gene id: 265072:MFLA_RS02495
uniprot id: Q1H428
names: Function
messages: This protein is a positive regulator for the phosphate regulon. Transcription of this operon is positively regulated by PhoB and PhoR when phosphate is limited.

265072:MFLA RS00380
gene id: 265072:MFLA_RS00380
uniprot id: Q1GXD1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DksA family.
messages: Cytoplasm
messages: Interacts directly with the RNA polymerase.
messages: Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters.

265072:MFLA RS08900
gene id: 265072:MFLA_RS08900
uniprot id: Q1H0I2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

265072:MFLA RS05975
gene id: 265072:MFLA_RS05975
uniprot id: Q1H249
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK.

265072:MFLA RS04135
gene id: 265072:MFLA_RS04135
uniprot id: Q1H360
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.

265072:MFLA RS01225
gene id: 265072:MFLA_RS01225
uniprot id: Q1H4S8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MlaE permease family.
messages: Cell inner membrane
messages: Membrane

265072:MFLA RS11610
gene id: 265072:MFLA_RS11610
uniprot id: Q1GYZ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell inner membrane

265072:MFLA RS09140
gene id: 265072:MFLA_RS09140
uniprot id: Q1H0D2
names: Function
names: Similarity
messages: Belongs to the SELO family.
messages: Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).

265072:MFLA RS06725
gene id: 265072:MFLA_RS06725
uniprot id: Q1H1Q4
names: Similarity
messages: Belongs to the MipA/OmpV family.

265072:MFLA RS05125
gene id: 265072:MFLA_RS05125
uniprot id: Q1H2L9
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

265072:MFLA RS12535
gene id: 265072:MFLA_RS12535
uniprot id: Q1GYG6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Monomer.

265072:MFLA RS00975
gene id: 265072:MFLA_RS00975
uniprot id: Q1H4X9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

265072:MFLA RS01745
gene id: 265072:MFLA_RS01745
uniprot id: Q1H4H7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell inner membrane

265072:MFLA RS06690
gene id: 265072:MFLA_RS06690
uniprot id: Q1H1R1
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

265072:MFLA RS09995
gene id: 265072:MFLA_RS09995
uniprot id: Q1GZW3
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

265072:MFLA RS11055
gene id: 265072:MFLA_RS11055
uniprot id: Q1GZA9
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily.
messages: Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway.

265072:MFLA RS12810
gene id: 265072:MFLA_RS12810
uniprot id: Q1GYB1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiK family.
messages: Cytoplasm
messages: Required for efficient ubiquinone (coenzyme Q) biosynthesis. UbiK is probably an accessory factor of Ubi enzymes and facilitates ubiquinone biosynthesis by acting as an assembly factor, a targeting factor, or both.

265072:MFLA RS02155
gene id: 265072:MFLA_RS02155
uniprot id: Q1H497
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

265072:MFLA RS04415
gene id: 265072:MFLA_RS04415
uniprot id: Q1H2L5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell inner membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

265072:MFLA RS01520
gene id: 265072:MFLA_RS01520
uniprot id: Q1H4M4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

265072:MFLA RS10695
gene id: 265072:MFLA_RS10695
uniprot id: Q1GZI1
names: Function
names: Similarity
messages: Belongs to the LpxK family.
messages: Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).

265072:MFLA RS13640
gene id: 265072:MFLA_RS13640
uniprot id: Q1GXU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Slam family.
messages: Cell outer membrane
messages: Membrane

265072:MFLA RS08660
gene id: 265072:MFLA_RS08660
uniprot id: Q1H0M8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the trans-sulfuration enzymes family. MetZ subfamily.
messages: Catalyzes the formation of L-homocysteine from O-succinyl-L-homoserine (OSHS) and hydrogen sulfide.
messages: Homotetramer.

265072:MFLA RS12710
gene id: 265072:MFLA_RS12710
uniprot id: Q1GYD1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

265072:MFLA RS00120
gene id: 265072:MFLA_RS00120
uniprot id: Q1GXA0
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

265072:MFLA RS12865
gene id: 265072:MFLA_RS12865
uniprot id: Q1GYA0
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

265072:MFLA RS03945
gene id: 265072:MFLA_RS03945
uniprot id: Q1H397
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Cytoplasm

265072:MFLA RS05060
gene id: 265072:MFLA_RS05060
uniprot id: Q1H2N2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

265072:MFLA RS10200
gene id: 265072:MFLA_RS10200
uniprot id: Q1GZS3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

265072:MFLA RS04750
gene id: 265072:MFLA_RS04750
uniprot id: Q1H2E8
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS1 family.
messages: Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.

265072:MFLA RS00600
gene id: 265072:MFLA_RS00600
uniprot id: Q1GXI3
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

265072:MFLA RS05435
gene id: 265072:MFLA_RS05435
uniprot id: Q1H2F7
names: Similarity
messages: Belongs to the 6-phosphogluconate dehydrogenase family.

265072:MFLA RS06990
gene id: 265072:MFLA_RS06990
uniprot id: Q1H1K2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
messages: Monomer.

265072:MFLA RS05145
gene id: 265072:MFLA_RS05145
uniprot id: Q1H2L5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell inner membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

265072:MFLA RS04090
gene id: 265072:MFLA_RS04090
uniprot id: Q1H369
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.

265072:MFLA RS08165
gene id: 265072:MFLA_RS08165
uniprot id: Q1H0X6
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

265072:MFLA RS03935
gene id: 265072:MFLA_RS03935
uniprot id: Q1H399
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIS family. GmhA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
messages: Cytoplasm
messages: Homotetramer.
messages: The reaction produces a racemic mixture of D-glycero-alpha-D-manno-heptose 7-phosphate and D-glycero-beta-D-manno-heptose 7-phosphate.

265072:MFLA RS12375
gene id: 265072:MFLA_RS12375
uniprot id: Q1GYJ8
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

265072:MFLA RS12005
gene id: 265072:MFLA_RS12005
uniprot id: Q1GYS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

265072:MFLA RS07045
gene id: 265072:MFLA_RS07045
uniprot id: Q1H1J1
names: Subcellular Location Annotation
messages: Membrane

265072:MFLA RS05775
gene id: 265072:MFLA_RS05775
uniprot id: Q1H290
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.

265072:MFLA RS02510
gene id: 265072:MFLA_RS02510
uniprot id: Q1H425
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

265072:MFLA RS11405
gene id: 265072:MFLA_RS11405
uniprot id: Q1GZ38
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

265072:MFLA RS08370
gene id: 265072:MFLA_RS08370
uniprot id: Q1H0T5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

265072:MFLA RS09555
gene id: 265072:MFLA_RS09555
uniprot id: Q1H051
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M20A family. DapE subfamily.
messages: Binds 2 Zn(2+) or Co(2+) ions per subunit.
messages: Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
messages: Homodimer.

265072:MFLA RS09170
gene id: 265072:MFLA_RS09170
uniprot id: Q1H0C6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

265072:MFLA RS10010
gene id: 265072:MFLA_RS10010
uniprot id: Q1GZW0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgH family.
messages: Cell outer membrane
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

265072:MFLA RS02845
gene id: 265072:MFLA_RS02845
uniprot id: Q50428
names: Function
messages: Involved in electron transfer.

265072:MFLA RS10930
gene id: 265072:MFLA_RS10930
uniprot id: Q1GZD4
names: Subcellular Location Annotation
messages: Membrane

265072:MFLA RS05520
gene id: 265072:MFLA_RS05520
uniprot id: Q1H2E0
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

265072:MFLA RS07715
gene id: 265072:MFLA_RS07715
uniprot id: Q1H164
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

265072:MFLA RS06380
gene id: 265072:MFLA_RS06380
uniprot id: Q1H1X2
names: Subcellular Location Annotation
messages: Cytoplasm

265072:MFLA RS05260
gene id: 265072:MFLA_RS05260
uniprot id: Q1H2J2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

265072:MFLA RS04440
gene id: 265072:MFLA_RS04440
uniprot id: Q1H2L0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the lipid A palmitoyltransferase family.
messages: Cell outer membrane
messages: Homodimer.
messages: Transfers a fatty acid residue from the sn-1 position of a phospholipid to the N-linked hydroxyfatty acid chain on the proximal unit of lipid A or its precursors.

265072:MFLA RS10480
gene id: 265072:MFLA_RS10480
uniprot id: Q1GZL7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

265072:MFLA RS03850
gene id: 265072:MFLA_RS03850
uniprot id: Q1H3B7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

265072:MFLA RS10230
gene id: 265072:MFLA_RS10230
uniprot id: Q1GZR7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also edits incorrectly charged L-seryl-tRNA(Thr).
messages: Cytoplasm
messages: Homodimer.

265072:MFLA RS05615
gene id: 265072:MFLA_RS05615
uniprot id: Q1H2C1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. RhlE subfamily.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in ribosome assembly. Has RNA-dependent ATPase activity and unwinds double-stranded RNA.

265072:MFLA RS01640
gene id: 265072:MFLA_RS01640
uniprot id: Q1H4J9
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.

265072:MFLA RS03240
gene id: 265072:MFLA_RS03240
uniprot id: Q1H3N2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

265072:MFLA RS03140
gene id: 265072:MFLA_RS03140
uniprot id: Q1H3Q3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic sulfate-binding protein family.
messages: Periplasm

265072:MFLA RS02475
gene id: 265072:MFLA_RS02475
uniprot id: Q1H432
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0060 family.
messages: Cell inner membrane

265072:MFLA RS01085
gene id: 265072:MFLA_RS01085
uniprot id: Q1H4V6
names: Function
names: Subcellular Location Annotation
messages: Periplasm
messages: Transfers electrons from cytochrome c551 to cytochrome oxidase.

265072:MFLA RS11465
gene id: 265072:MFLA_RS11465
uniprot id: Q1GZ26
names: Similarity
messages: Belongs to the pyruvate kinase family.

265072:MFLA RS10585
gene id: 265072:MFLA_RS10585
uniprot id: Q1GZJ7
names: Similarity
messages: Belongs to the peptidase M17 family.

265072:MFLA RS01340
gene id: 265072:MFLA_RS01340
uniprot id: Q1H4Q5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1C family.
messages: Periplasm

265072:MFLA RS07205
gene id: 265072:MFLA_RS07205
uniprot id: Q1H1G1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

265072:MFLA RS00905
gene id: 265072:MFLA_RS00905
uniprot id: Q1H4Z3
names: Cofactor
names: Similarity
messages: Belongs to the nitroreductase family.
messages: Binds 1 FMN per subunit.

265072:MFLA RS04500
gene id: 265072:MFLA_RS04500
uniprot id: Q1H2J8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

265072:MFLA RS03295
gene id: 265072:MFLA_RS03295
uniprot id: Q1H3M1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell inner membrane
messages: Membrane

265072:MFLA RS01135
gene id: 265072:MFLA_RS01135
uniprot id: Q1H4U6
names: Subcellular Location Annotation
messages: Membrane

265072:MFLA RS10600
gene id: 265072:MFLA_RS10600
uniprot id: Q1GZJ4
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

265072:MFLA RS10955
gene id: 265072:MFLA_RS10955
uniprot id: Q1GZC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP E family.
messages: Cytoplasm

265072:MFLA RS09075
gene id: 265072:MFLA_RS09075
uniprot id: Q1H0E6
names: Subcellular Location Annotation
messages: Membrane

265072:MFLA RS11835
gene id: 265072:MFLA_RS11835
uniprot id: Q1GYV3
names: Cofactor
messages: Binds 1 Fe(2+) ion per subunit.

265072:MFLA RS13325
gene id: 265072:MFLA_RS13325
uniprot id: Q1GY07
names: Similarity
messages: Belongs to the Nudix hydrolase family.

265072:MFLA RS05805
gene id: 265072:MFLA_RS05805
uniprot id: Q1H285
names: Similarity
messages: Belongs to the heat shock protein 70 family.

265072:MFLA RS04050
gene id: 265072:MFLA_RS04050
uniprot id: Q1H377
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.
messages: Cell inner membrane
messages: Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

265072:MFLA RS08620
gene id: 265072:MFLA_RS08620
uniprot id: Q1H0N6
names: Function
names: Similarity
messages: Belongs to the PqqB family.
messages: May be involved in the transport of PQQ or its precursor to the periplasm.

265072:MFLA RS13550
gene id: 265072:MFLA_RS13550
uniprot id: Q1GXW4
names: Similarity
messages: Belongs to the universal stress protein A family.

265072:MFLA RS10425
gene id: 265072:MFLA_RS10425
uniprot id: Q1GZM8
names: PTM
messages: Binds 1 heme c group covalently per subunit.

265072:MFLA RS11380
gene id: 265072:MFLA_RS11380
uniprot id: Q1GZ44
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

265072:MFLA RS12415
gene id: 265072:MFLA_RS12415
uniprot id: Q1GYJ0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobD/CbiB family.
messages: Cell membrane
messages: Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

265072:MFLA RS13120
gene id: 265072:MFLA_RS13120
uniprot id: Q1GY48
names: Similarity
messages: Belongs to the pirin family.

265072:MFLA RS02535
gene id: 265072:MFLA_RS02535
uniprot id: Q1H421
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

265072:MFLA RS11355
gene id: 265072:MFLA_RS11355
uniprot id: Q1GZ49
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

265072:MFLA RS06170
gene id: 265072:MFLA_RS06170
uniprot id: Q1H213
names: Similarity
messages: Belongs to the alkaline phosphatase family.

265072:MFLA RS03970
gene id: 265072:MFLA_RS03970
uniprot id: Q1H392
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

265072:MFLA RS08975
gene id: 265072:MFLA_RS08975
uniprot id: Q1H0G6
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family. GreB subfamily.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length.

265072:MFLA RS10095
gene id: 265072:MFLA_RS10095
uniprot id: Q1GZU3
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: Membrane

265072:MFLA RS10520
gene id: 265072:MFLA_RS10520
uniprot id: Q1GZK9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell inner membrane
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

265072:MFLA RS05135
gene id: 265072:MFLA_RS05135
uniprot id: Q1H2L7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RseB family.
messages: Periplasm

265072:MFLA RS01305
gene id: 265072:MFLA_RS01305
uniprot id: Q1H4R2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

265072:MFLA RS04685
gene id: 265072:MFLA_RS04685
uniprot id: Q1H2G1
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

265072:MFLA RS08150
gene id: 265072:MFLA_RS08150
uniprot id: Q1H0X9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Monomer.

265072:MFLA RS11095
gene id: 265072:MFLA_RS11095
uniprot id: Q1GZA1
names: Function
names: Similarity
messages: Belongs to the cyanase family.
messages: Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide.

265072:MFLA RS04055
gene id: 265072:MFLA_RS04055
uniprot id: Q1H376
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

265072:MFLA RS08410
gene id: 265072:MFLA_RS08410
uniprot id: Q1H0S7
names: Similarity
messages: Belongs to the bacterial secretin family.

265072:MFLA RS10105
gene id: 265072:MFLA_RS10105
uniprot id: Q1GZU1
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

265072:MFLA RS02230
gene id: 265072:MFLA_RS02230
uniprot id: Q1H483
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

265072:MFLA RS12020
gene id: 265072:MFLA_RS12020
uniprot id: Q1GYR7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

265072:MFLA RS13995
gene id: 265072:MFLA_RS13995
uniprot id: Q1GXN3
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

265072:MFLA RS00915
gene id: 265072:MFLA_RS00915
uniprot id: Q1H4Z1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Cell inner membrane
messages: Membrane

265072:MFLA RS08140
gene id: 265072:MFLA_RS08140
uniprot id: Q1H0Y1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

265072:MFLA RS10920
gene id: 265072:MFLA_RS10920
uniprot id: Q1GZD6
names: Function
names: Similarity
messages: Belongs to the GTP cyclohydrolase IV family.
messages: Converts GTP to 7,8-dihydroneopterin triphosphate.

265072:MFLA RS03870
gene id: 265072:MFLA_RS03870
uniprot id: Q1H3B3
names: Subcellular Location Annotation
messages: Membrane

265072:MFLA RS04485
gene id: 265072:MFLA_RS04485
uniprot id: Q1H2K1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

265072:MFLA RS06300
gene id: 265072:MFLA_RS06300
uniprot id: Q1H1Y8
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

265072:MFLA RS01260
gene id: 265072:MFLA_RS01260
uniprot id: Q1H4S1
names: Similarity
messages: Belongs to the glutaredoxin family. Monothiol subfamily.

265072:MFLA RS09750
gene id: 265072:MFLA_RS09750
uniprot id: Q1H012
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsB family.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

265072:MFLA RS05215
gene id: 265072:MFLA_RS05215
uniprot id: Q1H2K1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

265072:MFLA RS09955
gene id: 265072:MFLA_RS09955
uniprot id: Q1GZX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

265072:MFLA RS12910
gene id: 265072:MFLA_RS12910
uniprot id: Q1GY91
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

265072:MFLA RS09755
gene id: 265072:MFLA_RS09755
uniprot id: Q1H011
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

265072:MFLA RS05185
gene id: 265072:MFLA_RS05185
uniprot id: Q1H2K7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

265072:MFLA RS02445
gene id: 265072:MFLA_RS02445
uniprot id: Q1H443
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HemJ family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Catalyzes the oxidation of protoporphyrinogen IX to protoporphyrin IX.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

265072:MFLA RS02280
gene id: 265072:MFLA_RS02280
uniprot id: Q1H473
names: Subcellular Location Annotation
messages: Cell inner membrane

265072:MFLA RS03100
gene id: 265072:MFLA_RS03100
uniprot id: Q1H3R2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated exonuclease Cas4 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).
messages: Mg(2+) or Mn(2+) required for ssDNA cleavage activity.

265072:MFLA RS02100
gene id: 265072:MFLA_RS02100
uniprot id: Q1H4A8
names: Subcellular Location Annotation
messages: Membrane

265072:MFLA RS01430
gene id: 265072:MFLA_RS01430
uniprot id: Q1H4P2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

265072:MFLA RS13110
gene id: 265072:MFLA_RS13110
uniprot id: Q1GY50
names: Function
names: Similarity
messages: Belongs to the catalase family.
messages: Has an organic peroxide-dependent peroxidase activity.

265072:MFLA RS08905
gene id: 265072:MFLA_RS08905
uniprot id: Q1H0I1
names: Similarity
messages: Belongs to the UPF0225 family.

265072:MFLA RS03215
gene id: 265072:MFLA_RS03215
uniprot id: Q1H3N8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Binds 1 copper ion per subunit, denoted as copper B.
messages: Binds 2 heme groups per subunit, denoted as high- and low-spin.
messages: Membrane

265072:MFLA RS07110
gene id: 265072:MFLA_RS07110
uniprot id: Q1H1H8
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

265072:MFLA RS10460
gene id: 265072:MFLA_RS10460
uniprot id: Q1GZM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

265072:MFLA RS09970
gene id: 265072:MFLA_RS09970
uniprot id: Q1GZW8
names: Function
names: Similarity
messages: Belongs to the FlgM family.
messages: Responsible for the coupling of flagellin expression to flagellar assembly by preventing expression of the flagellin genes when a component of the middle class of proteins is defective. It negatively regulates flagellar genes by inhibiting the activity of FliA by directly binding to FliA.

265072:MFLA RS06370
gene id: 265072:MFLA_RS06370
uniprot id: Q1H1X4
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

265072:MFLA RS02895
gene id: 265072:MFLA_RS02895
uniprot id: Q1H3V2
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

265072:MFLA RS07210
gene id: 265072:MFLA_RS07210
uniprot id: Q1H1G0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

265072:MFLA RS08585
gene id: 265072:MFLA_RS08585
uniprot id: Q1H0P3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TER reductase family.
messages: Involved in the final reduction of the elongation cycle of fatty acid synthesis (FAS II). Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP).
messages: Monomer.

265072:MFLA RS05100
gene id: 265072:MFLA_RS05100
uniprot id: Q1H2M4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

265072:MFLA RS00540
gene id: 265072:MFLA_RS00540
uniprot id: Q1GXH5
names: Function
messages: Decarboxylates L-threonine-O-3-phosphate to yield (R)-1-amino-2-propanol O-2-phosphate, the precursor for the linkage between the nucleotide loop and the corrin ring in cobalamin.

265072:MFLA RS11695
gene id: 265072:MFLA_RS11695
uniprot id: Q1GYY1
names: Similarity
messages: Belongs to the thioredoxin family.

265072:MFLA RS01080
gene id: 265072:MFLA_RS01080
uniprot id: Q1H4V7
names: Subcellular Location Annotation
messages: Membrane

265072:MFLA RS06645
gene id: 265072:MFLA_RS06645
uniprot id: Q1H1S1
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

265072:MFLA RS08000
gene id: 265072:MFLA_RS08000
uniprot id: Q1H109
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

265072:MFLA RS01330
gene id: 265072:MFLA_RS01330
uniprot id: Q1H4Q7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatB family.
messages: Cell inner membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

265072:MFLA RS02360
gene id: 265072:MFLA_RS02360
uniprot id: Q1H458
names: Similarity
messages: Belongs to the glutamate synthase family.

265072:MFLA RS06800
gene id: 265072:MFLA_RS06800
uniprot id: Q1H1N9
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins.

265072:MFLA RS10845
gene id: 265072:MFLA_RS10845
uniprot id: Q1GZF1
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

265072:MFLA RS07175
gene id: 265072:MFLA_RS07175
uniprot id: Q1H1G7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZipA family.
messages: Cell inner membrane
messages: Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins.

265072:MFLA RS00235
gene id: 265072:MFLA_RS00235
uniprot id: Q1GXB9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

265072:MFLA RS00280
gene id: 265072:MFLA_RS00280
uniprot id: Q1GXD0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

265072:MFLA RS00365
gene id: 265072:MFLA_RS00365
uniprot id: Q1GXD4
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

265072:MFLA RS14075
gene id: 265072:MFLA_RS14075
uniprot id: Q1GXL7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.

265072:MFLA RS08185
gene id: 265072:MFLA_RS08185
uniprot id: Q1H0X2
names: Subcellular Location Annotation
messages: Membrane

265072:MFLA RS12190
gene id: 265072:MFLA_RS12190
uniprot id: Q1GYN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

265072:MFLA RS04005
gene id: 265072:MFLA_RS04005
uniprot id: Q1H386
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell inner membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

265072:MFLA RS13080
gene id: 265072:MFLA_RS13080
uniprot id: Q1GY56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

265072:MFLA RS00490
gene id: 265072:MFLA_RS00490
uniprot id: Q1GXG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0187 family.
messages: Membrane

265072:MFLA RS00685
gene id: 265072:MFLA_RS00685
uniprot id: Q1GXJ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

265072:MFLA RS05490
gene id: 265072:MFLA_RS05490
uniprot id: Q1H2E6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

265072:MFLA RS07255
gene id: 265072:MFLA_RS07255
uniprot id: Q1H1F2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 13 family.
messages: Cytoplasm

265072:MFLA RS10495
gene id: 265072:MFLA_RS10495
uniprot id: Q1GZL4
names: Function
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

265072:MFLA RS10060
gene id: 265072:MFLA_RS10060
uniprot id: Q1GZV0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliN/MopA/SpaO family.
messages: Membrane

265072:MFLA RS09735
gene id: 265072:MFLA_RS09735
uniprot id: Q1H015
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

265072:MFLA RS07620
gene id: 265072:MFLA_RS07620
uniprot id: Q1H184
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

265072:MFLA RS02595
gene id: 265072:MFLA_RS02595
uniprot id: Q1H409
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK.

265072:MFLA RS01475
gene id: 265072:MFLA_RS01475
uniprot id: Q1H4N3
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

265072:MFLA RS12750
gene id: 265072:MFLA_RS12750
uniprot id: Q1GYC3
names: Similarity
messages: Belongs to the UPF0250 family.

265072:MFLA RS13285
gene id: 265072:MFLA_RS13285
uniprot id: Q1GY15
names: Similarity
messages: Belongs to the HsdR family.

265072:MFLA RS14025
gene id: 265072:MFLA_RS14025
uniprot id: Q1GXM7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase delta chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

265072:MFLA RS12890
gene id: 265072:MFLA_RS12890
uniprot id: Q1GY95
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell inner membrane

265072:MFLA RS03355
gene id: 265072:MFLA_RS03355
uniprot id: Q1H3K9
names: Similarity
messages: Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.

265072:MFLA RS01805
gene id: 265072:MFLA_RS01805
uniprot id: Q1H4G5
names: Function
names: Similarity
messages: Belongs to the Dus family. DusB subfamily.
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

265072:MFLA RS11445
gene id: 265072:MFLA_RS11445
uniprot id: Q1GZ30
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

265072:MFLA RS07165
gene id: 265072:MFLA_RS07165
uniprot id: Q1H1G9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
messages: Cytoplasm

265072:MFLA RS07525
gene id: 265072:MFLA_RS07525
uniprot id: Q1H1A3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

265072:MFLA RS05725
gene id: 265072:MFLA_RS05725
uniprot id: Q1H299
names: Similarity
messages: Belongs to the Dps family.

265072:MFLA RS06095
gene id: 265072:MFLA_RS06095
uniprot id: Q1H227
names: Subcellular Location Annotation
messages: Membrane

265072:MFLA RS02620
gene id: 265072:MFLA_RS02620
uniprot id: Q1H404
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YajC family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the SecDF-YidC-YajC translocase complex. The SecDF-YidC-YajC translocase forms a supercomplex with SecYEG, called the holo-translocon (HTL).
messages: The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions.

265072:MFLA RS07950
gene id: 265072:MFLA_RS07950
uniprot id: Q1H118
names: Similarity
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Belongs to the peroxiredoxin family. Prx6 subfamily.

265072:MFLA RS00875
gene id: 265072:MFLA_RS00875
uniprot id: Q1H4Z9
names: Subcellular Location Annotation
messages: Membrane

265072:MFLA RS00355
gene id: 265072:MFLA_RS00355
uniprot id: Q1GXD6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

265072:MFLA RS11615
gene id: 265072:MFLA_RS11615
uniprot id: Q1GYZ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

265072:MFLA RS07770
gene id: 265072:MFLA_RS07770
uniprot id: Q1H153
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

265072:MFLA RS12510
gene id: 265072:MFLA_RS12510
uniprot id: Q1GYH1
names: Similarity
messages: Belongs to the HepT RNase toxin family.

265072:MFLA RS06955
gene id: 265072:MFLA_RS06955
uniprot id: Q1H1K9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

265072:MFLA RS00315
gene id: 265072:MFLA_RS00315
uniprot id: Q1GXC3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

265072:MFLA RS00770
gene id: 265072:MFLA_RS00770
uniprot id: Q1H519
names: Subcellular Location Annotation
messages: Cytoplasm

265072:MFLA RS10490
gene id: 265072:MFLA_RS10490
uniprot id: Q1GZL5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the complex I 75 kDa subunit family.
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

265072:MFLA RS06945
gene id: 265072:MFLA_RS06945
uniprot id: Q1H1L1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the GTP cyclohydrolase II family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.

265072:MFLA RS00865
gene id: 265072:MFLA_RS00865
uniprot id: Q1H501
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. METTL16/RlmF family.
messages: Cytoplasm
messages: Specifically methylates the adenine in position 1618 of 23S rRNA.

265072:MFLA RS04825
gene id: 265072:MFLA_RS04825
uniprot id: Q1H2D3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

265072:MFLA RS02555
gene id: 265072:MFLA_RS02555
uniprot id: Q1H417
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

265072:MFLA RS09760
gene id: 265072:MFLA_RS09760
uniprot id: Q1H010
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

265072:MFLA RS00350
gene id: 265072:MFLA_RS00350
uniprot id: Q1GXD7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

265072:MFLA RS05620
gene id: 265072:MFLA_RS05620
uniprot id: Q1H2C0
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

265072:MFLA RS06080
gene id: 265072:MFLA_RS06080
uniprot id: Q1H231
names: Subcellular Location Annotation
messages: Cytoplasm

265072:MFLA RS06805
gene id: 265072:MFLA_RS06805
uniprot id: Q1H1N8
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

265072:MFLA RS12635
gene id: 265072:MFLA_RS12635
uniprot id: Q1GYE6
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

265072:MFLA RS14005
gene id: 265072:MFLA_RS14005
uniprot id: Q1GXN1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

265072:MFLA RS13500
gene id: 265072:MFLA_RS13500
uniprot id: Q1GXX3
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

265072:MFLA RS01875
gene id: 265072:MFLA_RS01875
uniprot id: Q1H4F2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

265072:MFLA RS01035
gene id: 265072:MFLA_RS01035
uniprot id: Q1H4W7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

265072:MFLA RS10545
gene id: 265072:MFLA_RS10545
uniprot id: Q1GZK5
names: Similarity
messages: Belongs to the RecJ family.

265072:MFLA RS11185
gene id: 265072:MFLA_RS11185
uniprot id: Q1GZ82
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

265072:MFLA RS02820
gene id: 265072:MFLA_RS02820
uniprot id: Q50414
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: May be specifically involved in the processing, transport, and/or maturation of the MADH beta-subunit.

265072:MFLA RS08670
gene id: 265072:MFLA_RS08670
uniprot id: Q1H0M6
names: Subcellular Location Annotation
messages: Membrane

265072:MFLA RS11440
gene id: 265072:MFLA_RS11440
uniprot id: Q1GZ31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

265072:MFLA RS01555
gene id: 265072:MFLA_RS01555
uniprot id: Q1H4L7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell inner membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

265072:MFLA RS05635
gene id: 265072:MFLA_RS05635
uniprot id: Q1H2B7
names: Similarity
messages: Belongs to the YjdM family.

265072:MFLA RS13665
gene id: 265072:MFLA_RS13665
uniprot id: Q1GXU2
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

265072:MFLA RS05670
gene id: 265072:MFLA_RS05670
uniprot id: Q1H2B0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon.

265072:MFLA RS00635
gene id: 265072:MFLA_RS00635
uniprot id: Q1GXH6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Cob(I)alamin adenosyltransferase family.
messages: Cytoplasm
messages: Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids.

265072:MFLA RS08940
gene id: 265072:MFLA_RS08940
uniprot id: Q1H0H3
names: Similarity
messages: Belongs to the peptidase U62 family.

265072:MFLA RS10260
gene id: 265072:MFLA_RS10260
uniprot id: Q1GZR1
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

265072:MFLA RS07115
gene id: 265072:MFLA_RS07115
uniprot id: Q1H1H7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

265072:MFLA RS00430
gene id: 265072:MFLA_RS00430
uniprot id: Q1GXE0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

265072:MFLA RS08985
gene id: 265072:MFLA_RS08985
uniprot id: Q1H0G4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

265072:MFLA RS07930
gene id: 265072:MFLA_RS07930
uniprot id: Q1H122
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

265072:MFLA RS08240
gene id: 265072:MFLA_RS08240
uniprot id: Q1H0W2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Heme (hemin) importer (TC 3.A.1.14.5) family.
messages: Cell inner membrane
messages: Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (HmuV), two transmembrane proteins (HmuU) and a solute-binding protein (HmuT).

265072:MFLA RS07830
gene id: 265072:MFLA_RS07830
uniprot id: Q1H141
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.

265072:MFLA RS12825
gene id: 265072:MFLA_RS12825
uniprot id: Q1GYA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

265072:MFLA RS12405
gene id: 265072:MFLA_RS12405
uniprot id: Q1GYJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

265072:MFLA RS01160
gene id: 265072:MFLA_RS01160
uniprot id: Q1H4U1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

265072:MFLA RS05680
gene id: 265072:MFLA_RS05680
uniprot id: Q1H2A8
names: Similarity
messages: Belongs to the GSP E family.

265072:MFLA RS00070
gene id: 265072:MFLA_RS00070
uniprot id: Q1GXK9
names: Cofactor
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Binds 1 zinc ion per subunit. The zinc ion is important for the structural integrity of the protein.

265072:MFLA RS11485
gene id: 265072:MFLA_RS11485
uniprot id: Q1GZ21
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

265072:MFLA RS14080
gene id: 265072:MFLA_RS14080
uniprot id: Q1GXL6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell inner membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

265072:MFLA RS05445
gene id: 265072:MFLA_RS05445
uniprot id: Q1H2F5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.
messages: In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: In the N-terminal section; belongs to the MIP18 family.

265072:MFLA RS04720
gene id: 265072:MFLA_RS04720
uniprot id: Q1H2F4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.

265072:MFLA RS09270
gene id: 265072:MFLA_RS09270
uniprot id: Q1H0A9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0394 family.
messages: Membrane

265072:MFLA RS11065
gene id: 265072:MFLA_RS11065
uniprot id: Q1GZA7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
messages: Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
messages: Homodimer.

265072:MFLA RS04010
gene id: 265072:MFLA_RS04010
uniprot id: Q1H385
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

265072:MFLA RS08265
gene id: 265072:MFLA_RS08265
uniprot id: Q1H0V6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamD family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

265072:MFLA RS07220
gene id: 265072:MFLA_RS07220
uniprot id: Q1H1F8
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

265072:MFLA RS07035
gene id: 265072:MFLA_RS07035
uniprot id: Q1H1J3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

265072:MFLA RS07745
gene id: 265072:MFLA_RS07745
uniprot id: Q1H158
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

265072:MFLA RS13630
gene id: 265072:MFLA_RS13630
uniprot id: Q1GXU9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbA subfamily.
messages: Periplasm

265072:MFLA RS04120
gene id: 265072:MFLA_RS04120
uniprot id: Q1H363
names: Similarity
messages: Belongs to the HesB/IscA family.

265072:MFLA RS00525
gene id: 265072:MFLA_RS00525
uniprot id: Q1GXG0
names: Function
names: Similarity
messages: Belongs to the CobT family.
messages: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).

265072:MFLA RS13570
gene id: 265072:MFLA_RS13570
uniprot id: Q1GXW1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).

265072:MFLA RS07570
gene id: 265072:MFLA_RS07570
uniprot id: Q1H194
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

265072:MFLA RS05840
gene id: 265072:MFLA_RS05840
uniprot id: Q1H278
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

265072:MFLA RS10140
gene id: 265072:MFLA_RS10140
uniprot id: Q1GZT4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

265072:MFLA RS12175
gene id: 265072:MFLA_RS12175
uniprot id: Q1GYN8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.

265072:MFLA RS08070
gene id: 265072:MFLA_RS08070
uniprot id: Q1H0Z5
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

265072:MFLA RS00475
gene id: 265072:MFLA_RS00475
uniprot id: Q1GXE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

265072:MFLA RS02335
gene id: 265072:MFLA_RS02335
uniprot id: Q1H463
names: Similarity
messages: Belongs to the GcvT family.

265072:MFLA RS04315
gene id: 265072:MFLA_RS04315
uniprot id: Q1H2N6
names: Similarity
messages: Belongs to the bacterial secretin family.

265072:MFLA RS02785
gene id: 265072:MFLA_RS02785
uniprot id: Q1H3X5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell inner membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

265072:MFLA RS00870
gene id: 265072:MFLA_RS00870
uniprot id: Q1H500
names: Subcellular Location Annotation
messages: Membrane

265072:MFLA RS00270
gene id: 265072:MFLA_RS00270
uniprot id: Q1GXB2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

265072:MFLA RS03055
gene id: 265072:MFLA_RS03055
uniprot id: Q1H3S1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

265072:MFLA RS09585
gene id: 265072:MFLA_RS09585
uniprot id: Q1H045
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Cell membrane
messages: Membrane

265072:MFLA RS10580
gene id: 265072:MFLA_RS10580
uniprot id: Q1GZJ8
names: Similarity
messages: Belongs to the prokaryotic/mitochondrial release factor family.

265072:MFLA RS12975
gene id: 265072:MFLA_RS12975
uniprot id: Q1GY78
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

265072:MFLA RS08650
gene id: 265072:MFLA_RS08650
uniprot id: Q1H0N0
names: Similarity
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.

265072:MFLA RS00580
gene id: 265072:MFLA_RS00580
uniprot id: Q1GXG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

265072:MFLA RS11700
gene id: 265072:MFLA_RS11700
uniprot id: Q1GYY0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

265072:MFLA RS11305
gene id: 265072:MFLA_RS11305
uniprot id: Q1GZ59
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

265072:MFLA RS08635
gene id: 265072:MFLA_RS08635
uniprot id: Q1H0N3
names: Function
names: Subcellular Location Annotation
messages: Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.
messages: Cytoplasm

265072:MFLA RS01850
gene id: 265072:MFLA_RS01850
uniprot id: Q1H4F7
names: Similarity
messages: Belongs to the LOG family.

265072:MFLA RS09830
gene id: 265072:MFLA_RS09830
uniprot id: Q1GZZ5
names: Similarity
messages: Belongs to the phosphohexose mutase family.

265072:MFLA RS08750
gene id: 265072:MFLA_RS08750
uniprot id: Q1H0L0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm
messages: Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.

265072:MFLA RS13585
gene id: 265072:MFLA_RS13585
uniprot id: Q1GXV8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.

265072:MFLA RS10185
gene id: 265072:MFLA_RS10185
uniprot id: Q1GZS5
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

265072:MFLA RS09445
gene id: 265072:MFLA_RS09445
uniprot id: Q1H073
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

265072:MFLA RS01620
gene id: 265072:MFLA_RS01620
uniprot id: Q1H4K3
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

265072:MFLA RS04075
gene id: 265072:MFLA_RS04075
uniprot id: Q1H372
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

265072:MFLA RS10040
gene id: 265072:MFLA_RS10040
uniprot id: Q1GZV4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliR/MopE/SpaR family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

265072:MFLA RS04130
gene id: 265072:MFLA_RS04130
uniprot id: Q1H361
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
messages: Cytoplasm
messages: Homodimer. Forms a heterotetramer with IscU, interacts with other sulfur acceptors.
messages: Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.

265072:MFLA RS01055
gene id: 265072:MFLA_RS01055
uniprot id: Q1H4W3
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

265072:MFLA RS01300
gene id: 265072:MFLA_RS01300
uniprot id: Q1H4R3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

265072:MFLA RS02910
gene id: 265072:MFLA_RS02910
uniprot id: Q1H3V0
names: Similarity
messages: Belongs to the aspartokinase family.

265072:MFLA RS01295
gene id: 265072:MFLA_RS01295
uniprot id: Q1H4R4
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

265072:MFLA RS07695
gene id: 265072:MFLA_RS07695
uniprot id: Q1H168
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase MltG family.
messages: Cell inner membrane
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

265072:MFLA RS05165
gene id: 265072:MFLA_RS05165
uniprot id: Q1H2L1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell inner membrane
messages: Cytoplasm
messages: Monomer.

265072:MFLA RS13295
gene id: 265072:MFLA_RS13295
uniprot id: Q1GY13
names: Similarity
messages: Belongs to the glycosyltransferase 1 family.

265072:MFLA RS03795
gene id: 265072:MFLA_RS03795
uniprot id: Q1H3C8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

265072:MFLA RS01495
gene id: 265072:MFLA_RS01495
uniprot id: Q1H4M9
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

265072:MFLA RS12725
gene id: 265072:MFLA_RS12725
uniprot id: Q1GYC8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transpeptidase family. MrdA subfamily.
messages: Catalyzes cross-linking of the peptidoglycan cell wall.
messages: Cell inner membrane

265072:MFLA RS01470
gene id: 265072:MFLA_RS01470
uniprot id: Q1H4N4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

265072:MFLA RS00815
gene id: 265072:MFLA_RS00815
uniprot id: Q1H511
names: Subcellular Location Annotation
messages: Membrane

265072:MFLA RS09850
gene id: 265072:MFLA_RS09850
uniprot id: Q1GZZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CheZ family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P).

265072:MFLA RS06585
gene id: 265072:MFLA_RS06585
uniprot id: Q1H1T3
names: Function
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
messages: Catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate and ammonia.

265072:MFLA RS13950
gene id: 265072:MFLA_RS13950
uniprot id: Q1GXP1
names: Cofactor
names: Function
names: Subunit
messages: Alpha(8)-beta(8). The alpha component is a flavoprotein, the beta component is a hemoprotein.
messages: Binds 1 FAD per subunit.
messages: Binds 1 FMN per subunit.
messages: Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component.

265072:MFLA RS10590
gene id: 265072:MFLA_RS10590
uniprot id: Q1GZJ6
names: Function
names: Subunit
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
messages: Homodimer. Part of the PDH complex, consisting of multiple copies of pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

265072:MFLA RS06085
gene id: 265072:MFLA_RS06085
uniprot id: Q1H230
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

265072:MFLA RS02885
gene id: 265072:MFLA_RS02885
uniprot id: Q1H3V4
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

265072:MFLA RS04030
gene id: 265072:MFLA_RS04030
uniprot id: Q1H381
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of sn-l,2-diacylglycerol (DAG) to phosphatidic acid. Involved in the recycling of diacylglycerol produced as a by-product during membrane-derived oligosaccharide (MDO) biosynthesis.
messages: Cell inner membrane
messages: Membrane

265072:MFLA RS10910
gene id: 265072:MFLA_RS10910
uniprot id: Q1GZD8
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

265072:MFLA RS01145
gene id: 265072:MFLA_RS01145
uniprot id: Q1H4U4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

265072:MFLA RS11915
gene id: 265072:MFLA_RS11915
uniprot id: Q1GYT8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

265072:MFLA RS01870
gene id: 265072:MFLA_RS01870
uniprot id: Q1H4F3
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

265072:MFLA RS08820
gene id: 265072:MFLA_RS08820
uniprot id: Q1H0J8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

265072:MFLA RS01505
gene id: 265072:MFLA_RS01505
uniprot id: Q1H4M7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

265072:MFLA RS10090
gene id: 265072:MFLA_RS10090
uniprot id: Q1GZU4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliH family.
messages: Cytoplasm
messages: Needed for flagellar regrowth and assembly.

265072:MFLA RS10505
gene id: 265072:MFLA_RS10505
uniprot id: Q1GZL2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

265072:MFLA RS00995
gene id: 265072:MFLA_RS00995
uniprot id: Q1H4X5
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

265072:MFLA RS06475
gene id: 265072:MFLA_RS06475
uniprot id: Q1H1V4
names: Similarity
messages: Belongs to the HSP15 family.

265072:MFLA RS06995
gene id: 265072:MFLA_RS06995
uniprot id: Q1H1K1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
messages: Homotetramer.
messages: Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.

265072:MFLA RS01615
gene id: 265072:MFLA_RS01615
uniprot id: Q1H4K4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

265072:MFLA RS04435
gene id: 265072:MFLA_RS04435
uniprot id: Q1H2L1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell inner membrane
messages: Cytoplasm
messages: Monomer.

265072:MFLA RS12915
gene id: 265072:MFLA_RS12915
uniprot id: Q1GY90
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

265072:MFLA RS07340
gene id: 265072:MFLA_RS07340
uniprot id: Q1H1D5
names: Cofactor
names: Similarity
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Binds 1 copper ion per subunit, denoted as copper B.
messages: Binds 2 heme groups per subunit, denoted as high- and low-spin.

265072:MFLA RS07845
gene id: 265072:MFLA_RS07845
uniprot id: Q1H138
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

265072:MFLA RS03755
gene id: 265072:MFLA_RS03755
uniprot id: Q1H3D6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell inner membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

265072:MFLA RS04395
gene id: 265072:MFLA_RS04395
uniprot id: Q1H2L9
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

265072:MFLA RS11280
gene id: 265072:MFLA_RS11280
uniprot id: Q1GZ64
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

265072:MFLA RS02055
gene id: 265072:MFLA_RS02055
uniprot id: Q1H4B7
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

265072:MFLA RS14050
gene id: 265072:MFLA_RS14050
uniprot id: Q1GXM2
names: Function
names: Similarity
messages: Belongs to the ParB family.
messages: Involved in chromosome partition. Localize to both poles of the predivisional cell following completion of DNA replication. Binds to the DNA origin of replication.

265072:MFLA RS11870
gene id: 265072:MFLA_RS11870
uniprot id: Q1GYU7
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

265072:MFLA RS04445
gene id: 265072:MFLA_RS04445
uniprot id: Q1H2K9
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

265072:MFLA RS07755
gene id: 265072:MFLA_RS07755
uniprot id: Q1H156
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YceF subfamily.
messages: Cytoplasm
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes 7-methyl-GTP (m(7)GTP). May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

265072:MFLA RS05655
gene id: 265072:MFLA_RS05655
uniprot id: Q1H2B3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose 5-phosphate isomerase family.
messages: Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
messages: Homodimer.

265072:MFLA RS00030
gene id: 265072:MFLA_RS00030
uniprot id: Q1GXK5
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

265072:MFLA RS02195
gene id: 265072:MFLA_RS02195
uniprot id: Q1H490
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ApbE family.
messages: Cell inner membrane
messages: Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.
messages: Magnesium. Can also use manganese.

265072:MFLA RS02925
gene id: 265072:MFLA_RS02925
uniprot id: Q1H3U7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

265072:MFLA RS06780
gene id: 265072:MFLA_RS06780
uniprot id: Q1H1P3
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

265072:MFLA RS01540
gene id: 265072:MFLA_RS01540
uniprot id: Q1H4M0
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

265072:MFLA RS01315
gene id: 265072:MFLA_RS01315
uniprot id: Q1H4R0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA-PH family.
messages: Cytoplasm

265072:MFLA RS06535
gene id: 265072:MFLA_RS06535
uniprot id: Q1H1U2
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

265072:MFLA RS01860
gene id: 265072:MFLA_RS01860
uniprot id: Q9RAM6
names: Similarity
messages: Belongs to the pseudomonas-type ThrB family.

265072:MFLA RS09450
gene id: 265072:MFLA_RS09450
uniprot id: Q1H072
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

265072:MFLA RS14065
gene id: 265072:MFLA_RS14065
uniprot id: Q1GXL9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

265072:MFLA RS04730
gene id: 265072:MFLA_RS04730
uniprot id: Q1H2F2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the OMP decarboxylase family. Type 1 subfamily.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
messages: Homodimer.

265072:MFLA RS04155
gene id: 265072:MFLA_RS04155
uniprot id: Q1H356
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

265072:MFLA RS00140
gene id: 265072:MFLA_RS00140
uniprot id: Q1GX96
names: Similarity
messages: Belongs to the CutA family.

265072:MFLA RS02120
gene id: 265072:MFLA_RS02120
uniprot id: Q1H4A4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acetylates the N-terminal alanine of ribosomal protein S18.
messages: Belongs to the acetyltransferase family. RimI subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

265072:MFLA RS09990
gene id: 265072:MFLA_RS09990
uniprot id: Q1GZW4
names: Function
names: Similarity
messages: Belongs to the FlgD family.
messages: Required for flagellar hook formation. May act as a scaffolding protein.

265072:MFLA RS11890
gene id: 265072:MFLA_RS11890
uniprot id: Q1GYU3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell inner membrane
messages: Probably interacts with PlsX.

265072:MFLA RS02625
gene id: 265072:MFLA_RS02625
uniprot id: Q1H403
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

265072:MFLA RS09255
gene id: 265072:MFLA_RS09255
uniprot id: Q1H0B2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0114 family.
messages: Cell membrane
messages: Membrane

265072:MFLA RS06860
gene id: 265072:MFLA_RS06860
uniprot id: Q1H1M8
names: Similarity
messages: Belongs to the GSP E family.

265072:MFLA RS01255
gene id: 265072:MFLA_RS01255
uniprot id: Q1H4S2
names: Similarity
messages: Belongs to the BolA/IbaG family.

265072:MFLA RS12380
gene id: 265072:MFLA_RS12380
uniprot id: Q1GYJ7
names: Subcellular Location Annotation
messages: Membrane

265072:MFLA RS07225
gene id: 265072:MFLA_RS07225
uniprot id: Q1H1F7
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

265072:MFLA RS07075
gene id: 265072:MFLA_RS07075
uniprot id: Q1H1I5
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

265072:MFLA RS07105
gene id: 265072:MFLA_RS07105
uniprot id: Q1H1H9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Catalyzes the last two steps in the biosynthesis of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the DAO family.
messages: In the N-terminal section; belongs to the methyltransferase superfamily. tRNA (mnm(5)s(2)U34)-methyltransferase family.

265072:MFLA RS06320
gene id: 265072:MFLA_RS06320
uniprot id: Q1H1Y4
names: Similarity
messages: Belongs to the spermidine/spermine synthase family.

265072:MFLA RS08435
gene id: 265072:MFLA_RS08435
uniprot id: Q1H0S3
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

265072:MFLA RS00210
gene id: 265072:MFLA_RS00210
uniprot id: Q1GXA4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

265072:MFLA RS00195
gene id: 265072:MFLA_RS00195
uniprot id: Q1GXA7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

265072:MFLA RS02850
gene id: 265072:MFLA_RS02850
uniprot id: Q50400
names: Function
names: Subcellular Location Annotation
messages: Periplasm
messages: Probable electron acceptor for methylamine dehydrogenase.

265072:MFLA RS12720
gene id: 265072:MFLA_RS12720
uniprot id: Q1GYC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Membrane

265072:MFLA RS11395
gene id: 265072:MFLA_RS11395
uniprot id: Q1GZ40
names: Similarity
messages: Belongs to the Nudix hydrolase family.

265072:MFLA RS06290
gene id: 265072:MFLA_RS06290
uniprot id: Q1H1Z0
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

265072:MFLA RS03005
gene id: 265072:MFLA_RS03005
uniprot id: Q1H3T1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FBPase class 1 family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.

265072:MFLA RS10625
gene id: 265072:MFLA_RS10625
uniprot id: Q1GZI9
names: Function
names: Similarity
messages: Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor.
messages: Belongs to the biotin--protein ligase family.

265072:MFLA RS03890
gene id: 265072:MFLA_RS03890
uniprot id: Q1H3A9
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

265072:MFLA RS14045
gene id: 265072:MFLA_RS14045
uniprot id: Q1GXM3
names: Subcellular Location Annotation
messages: Membrane

265072:MFLA RS13005
gene id: 265072:MFLA_RS13005
uniprot id: Q1GY71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

265072:MFLA RS04045
gene id: 265072:MFLA_RS04045
uniprot id: Q1H378
names: Function
names: Similarity
messages: Belongs to the DadA oxidoreductase family.
messages: Oxidative deamination of D-amino acids.

265072:MFLA RS09565
gene id: 265072:MFLA_RS09565
uniprot id: Q1H049
names: Subcellular Location Annotation
messages: Membrane

265072:MFLA RS05205
gene id: 265072:MFLA_RS05205
uniprot id: Q1H2K3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

265072:MFLA RS09870
gene id: 265072:MFLA_RS09870
uniprot id: Q1GZY8
names: Function
messages: Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP.

265072:MFLA RS09035
gene id: 265072:MFLA_RS09035
uniprot id: Q1H0F4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UreF family.
messages: Cytoplasm
messages: Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
messages: UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

265072:MFLA RS04880
gene id: 265072:MFLA_RS04880
uniprot id: Q1H2C2
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

265072:MFLA RS00170
gene id: 265072:MFLA_RS00170
uniprot id: Q1GXA1
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

265072:MFLA RS11750
gene id: 265072:MFLA_RS11750
uniprot id: Q1GYX0
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

265072:MFLA RS06345
gene id: 265072:MFLA_RS06345
uniprot id: Q1H1X9
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the peroxiredoxin family. Tpx subfamily.
messages: Homodimer.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. In this atypical 2-Cys peroxiredoxin, C(R) is present in the same subunit to form an intramolecular disulfide. The disulfide is subsequently reduced by thioredoxin.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

265072:MFLA RS14030
gene id: 265072:MFLA_RS14030
uniprot id: Q1GXM6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell inner membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.

265072:MFLA RS07575
gene id: 265072:MFLA_RS07575
uniprot id: Q1H193
names: Similarity
messages: Belongs to the histone deacetylase family.

265072:MFLA RS12385
gene id: 265072:MFLA_RS12385
uniprot id: Q1GYJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

265072:MFLA RS09770
gene id: 265072:MFLA_RS09770
uniprot id: Q1H008
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.

265072:MFLA RS14015
gene id: 265072:MFLA_RS14015
uniprot id: Q1GXM9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

265072:MFLA RS00155
gene id: 265072:MFLA_RS00155
uniprot id: Q1GX93
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Involved in a late step of protoheme IX synthesis.
messages: Membrane

265072:MFLA RS10740
gene id: 265072:MFLA_RS10740
uniprot id: Q1GZH2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

265072:MFLA RS12565
gene id: 265072:MFLA_RS12565
uniprot id: Q1GYG0
names: Similarity
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.
messages: Membrane

265072:MFLA RS06485
gene id: 265072:MFLA_RS06485
uniprot id: Q1H1V2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

265072:MFLA RS01780
gene id: 265072:MFLA_RS01780
uniprot id: Q1H4H0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the aerobic coproporphyrinogen-III oxidase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX.

265072:MFLA RS02630
gene id: 265072:MFLA_RS02630
uniprot id: Q1H402
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

265072:MFLA RS03000
gene id: 265072:MFLA_RS03000
uniprot id: Q1H3T2
names: Similarity
messages: Belongs to the MlaA family.

265072:MFLA RS01685
gene id: 265072:MFLA_RS01685
uniprot id: Q1H4J0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

265072:MFLA RS10215
gene id: 265072:MFLA_RS10215
uniprot id: Q1GZS0
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

265072:MFLA RS08755
gene id: 265072:MFLA_RS08755
uniprot id: Q1H0K9
names: Caution
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

265072:MFLA RS11295
gene id: 265072:MFLA_RS11295
uniprot id: Q1GZ61
names: Function
names: Similarity
messages: Belongs to the ribF family.
messages: Catalyzes the phosphorylation of riboflavin to FMN followed by the adenylation of FMN to FAD.

265072:MFLA RS13355
gene id: 265072:MFLA_RS13355
uniprot id: Q1GY01
names: Subcellular Location Annotation
messages: Membrane

265072:MFLA RS11195
gene id: 265072:MFLA_RS11195
uniprot id: Q1GZ80
names: Similarity
messages: Belongs to the UPF0047 family.

265072:MFLA RS06495
gene id: 265072:MFLA_RS06495
uniprot id: Q1H1V0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

265072:MFLA RS06750
gene id: 265072:MFLA_RS06750
uniprot id: Q1H1P9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

265072:MFLA RS11565
gene id: 265072:MFLA_RS11565
uniprot id: Q1GZ06
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell inner membrane
messages: Self-interacts. Interacts with FtsZ.

265072:MFLA RS01460
gene id: 265072:MFLA_RS01460
uniprot id: Q1H4N6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

265072:MFLA RS07720
gene id: 265072:MFLA_RS07720
uniprot id: Q1H163
names: Similarity
messages: Belongs to the fabD family.

265072:MFLA RS00680
gene id: 265072:MFLA_RS00680
uniprot id: Q1GXJ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose 5-phosphate isomerase family.
messages: Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
messages: Homodimer.

265072:MFLA RS07400
gene id: 265072:MFLA_RS07400
uniprot id: Q1H1C4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

265072:MFLA RS06595
gene id: 265072:MFLA_RS06595
uniprot id: Q1H1T1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

265072:MFLA RS09815
gene id: 265072:MFLA_RS09815
uniprot id: Q1GZZ9
names: Similarity
messages: Belongs to the phosphohexose mutase family.

265072:MFLA RS05830
gene id: 265072:MFLA_RS05830
uniprot id: Q1H280
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

265072:MFLA RS05850
gene id: 265072:MFLA_RS05850
uniprot id: Q1H276
names: Similarity
messages: Belongs to the UPF0125 (RnfH) family.

265072:MFLA RS00060
gene id: 265072:MFLA_RS00060
uniprot id: Q1GXL1
names: Similarity
messages: Belongs to the MQO family.

265072:MFLA RS03775
gene id: 265072:MFLA_RS03775
uniprot id: Q1H3D2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

265072:MFLA RS08260
gene id: 265072:MFLA_RS08260
uniprot id: Q1H0V7
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

265072:MFLA RS04410
gene id: 265072:MFLA_RS04410
uniprot id: Q1H2L6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1C family.
messages: Periplasm

265072:MFLA RS01400
gene id: 265072:MFLA_RS01400
uniprot id: Q1H4P8
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

265072:MFLA RS06440
gene id: 265072:MFLA_RS06440
uniprot id: Q1H1W0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

265072:MFLA RS14010
gene id: 265072:MFLA_RS14010
uniprot id: Q1GXN0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

265072:MFLA RS13785
gene id: 265072:MFLA_RS13785
uniprot id: Q1GXR9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

265072:MFLA RS01270
gene id: 265072:MFLA_RS01270
uniprot id: Q1H4R9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Lacks the C-terminal regulatory region which is replaced by HisZ.

265072:MFLA RS09610
gene id: 265072:MFLA_RS09610
uniprot id: Q1H040
names: Similarity
messages: Belongs to the BolA/IbaG family.

265072:MFLA RS05045
gene id: 265072:MFLA_RS05045
uniprot id: Q1H2N6
names: Similarity
messages: Belongs to the bacterial secretin family.

265072:MFLA RS04745
gene id: 265072:MFLA_RS04745
uniprot id: Q1H2E9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

265072:MFLA RS09040
gene id: 265072:MFLA_RS09040
uniprot id: Q1H0F3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UreE family.
messages: Cytoplasm
messages: Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly.

265072:MFLA RS08615
gene id: 265072:MFLA_RS08615
uniprot id: Q1H0N7
names: Function
names: Similarity
messages: Belongs to the PqqC family.
messages: Ring cyclization and eight-electron oxidation of 3a-(2-amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline-7,9-dicarboxylic-acid to PQQ.

265072:MFLA RS07000
gene id: 265072:MFLA_RS07000
uniprot id: Q1H1K0
names: Similarity
messages: Belongs to the glycosyl hydrolase 57 family.

265072:MFLA RS01580
gene id: 265072:MFLA_RS01580
uniprot id: Q1H4L1
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

265072:MFLA RS11885
gene id: 265072:MFLA_RS11885
uniprot id: Q1GYU4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

265072:MFLA RS11605
gene id: 265072:MFLA_RS11605
uniprot id: Q1GYZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

265072:MFLA RS10995
gene id: 265072:MFLA_RS10995
uniprot id: Q1GZC1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptD family.
messages: Cell outer membrane
messages: Component of the lipopolysaccharide transport and assembly complex. Interacts with LptE and LptA.
messages: Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.

265072:MFLA RS12610
gene id: 265072:MFLA_RS12610
uniprot id: Q1GYF1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

265072:MFLA RS12795
gene id: 265072:MFLA_RS12795
uniprot id: Q1GYB4
names: Function
names: Similarity
messages: Belongs to the MurCDEF family. Mpl subfamily.
messages: Reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl-meso-diaminopimelate by linking it to UDP-N-acetylmuramate.

265072:MFLA RS04125
gene id: 265072:MFLA_RS04125
uniprot id: Q1H362
names: Function
names: Similarity
messages: A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters.
messages: Belongs to the NifU family.

265072:MFLA RS06220
gene id: 265072:MFLA_RS06220
uniprot id: Q1H204
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HsdR family.
messages: Subunit R is required for both nuclease and ATPase activities, but not for modification.
messages: The type I restriction/modification system is composed of three polypeptides R, M and S.

265072:MFLA RS12695
gene id: 265072:MFLA_RS12695
uniprot id: Q1GYD4
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

265072:MFLA RS10970
gene id: 265072:MFLA_RS10970
uniprot id: Q1GZC6
names: Similarity
messages: Belongs to the UbiH/COQ6 family.

265072:MFLA RS11030
gene id: 265072:MFLA_RS11030
uniprot id: Q1GZB4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LptE lipoprotein family.
messages: Component of the lipopolysaccharide transport and assembly complex. Interacts with LptD.
messages: Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane.

265072:MFLA RS03845
gene id: 265072:MFLA_RS03845
uniprot id: Q1H3B8
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

265072:MFLA RS08060
gene id: 265072:MFLA_RS08060
uniprot id: Q1H0Z7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

265072:MFLA RS01030
gene id: 265072:MFLA_RS01030
uniprot id: Q1H4W8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

265072:MFLA RS09230
gene id: 265072:MFLA_RS09230
uniprot id: Q1H0B7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

265072:MFLA RS11930
gene id: 265072:MFLA_RS11930
uniprot id: Q1GYT5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).

265072:MFLA RS09485
gene id: 265072:MFLA_RS09485
uniprot id: Q1H065
names: Caution
names: Function
names: Similarity
messages: Belongs to the transcriptional regulatory CopG/NikR family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transcriptional regulator.

265072:MFLA RS00900
gene id: 265072:MFLA_RS00900
uniprot id: Q1H4Z4
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

265072:MFLA RS10175
gene id: 265072:MFLA_RS10175
uniprot id: Q1GZS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

265072:MFLA RS06275
gene id: 265072:MFLA_RS06275
uniprot id: Q1H1Z3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

265072:MFLA RS03950
gene id: 265072:MFLA_RS03950
uniprot id: Q1H396
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

265072:MFLA RS08470
gene id: 265072:MFLA_RS08470
uniprot id: Q1H0R6
names: Similarity
messages: Belongs to the SIS family. PHI subfamily.

265072:MFLA RS09765
gene id: 265072:MFLA_RS09765
uniprot id: Q1H009
names: Activity Regulation
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.

265072:MFLA RS07995
gene id: 265072:MFLA_RS07995
uniprot id: Q1H110
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

265072:MFLA RS07580
gene id: 265072:MFLA_RS07580
uniprot id: Q1H192
names: Cofactor
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.

265072:MFLA RS07705
gene id: 265072:MFLA_RS07705
uniprot id: Q1H166
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

265072:MFLA RS03455
gene id: 265072:MFLA_RS03455
uniprot id: Q1H3J3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

265072:MFLA RS03750
gene id: 265072:MFLA_RS03750
uniprot id: Q1H3D7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division. Important for assembly or stability of the septal ring.

265072:MFLA RS00005
gene id: 265072:MFLA_RS00005
uniprot id: Q1GXK1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

265072:MFLA RS09305
gene id: 265072:MFLA_RS09305
uniprot id: Q1H0A1
names: Function
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
messages: Catalyzes two reactions in de novo purine nucleotide biosynthesis. Catalyzes the breakdown of 5-aminoimidazole- (N-succinylocarboxamide) ribotide (SAICAR or 2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate) to 5-aminoimidazole-4-carboxamide ribotide (AICAR or 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide) and fumarate, and of adenylosuccinate (ADS or N(6)-(1,2-dicarboxyethyl)-AMP) to adenosine monophosphate (AMP) and fumarate.

265072:MFLA RS01720
gene id: 265072:MFLA_RS01720
uniprot id: Q1H4I2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

265072:MFLA RS09910
gene id: 265072:MFLA_RS09910
uniprot id: Q1GZY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Membrane

265072:MFLA RS11620
gene id: 265072:MFLA_RS11620
uniprot id: Q1GYZ6
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

265072:MFLA RS10510
gene id: 265072:MFLA_RS10510
uniprot id: Q1GZL1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 30 kDa subunit family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

265072:MFLA RS04715
gene id: 265072:MFLA_RS04715
uniprot id: Q1H2F5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.
messages: In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: In the N-terminal section; belongs to the MIP18 family.

265072:MFLA RS01545
gene id: 265072:MFLA_RS01545
uniprot id: Q1H4L9
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

265072:MFLA RS03185
gene id: 265072:MFLA_RS03185
uniprot id: Q1H3P4
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

265072:MFLA RS11155
gene id: 265072:MFLA_RS11155
uniprot id: Q1GZ88
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide.

265072:MFLA RS01350
gene id: 265072:MFLA_RS01350
uniprot id: Q1H4Q3
names: Similarity
messages: Belongs to the GST superfamily. HSP26 family.

265072:MFLA RS01325
gene id: 265072:MFLA_RS01325
uniprot id: Q1H4Q8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell inner membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

265072:MFLA RS06460
gene id: 265072:MFLA_RS06460
uniprot id: Q1H1V7
names: Similarity
messages: Belongs to the MoaD family.

265072:MFLA RS12030
gene id: 265072:MFLA_RS12030
uniprot id: Q1GYR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

265072:MFLA RS08135
gene id: 265072:MFLA_RS08135
uniprot id: Q1H0Y2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the band 7/mec-2 family. HflK subfamily.
messages: HflC and HflK could encode or regulate a protease.
messages: HflC and HflK may interact to form a multimeric complex.
messages: Membrane

265072:MFLA RS07350
gene id: 265072:MFLA_RS07350
uniprot id: Q1H1D3
names: Similarity
messages: Belongs to the manganese catalase family.

265072:MFLA RS02675
gene id: 265072:MFLA_RS02675
uniprot id: Q1H3Z4
names: Subcellular Location Annotation
messages: Membrane

265072:MFLA RS11795
gene id: 265072:MFLA_RS11795
uniprot id: Q1GYW1
names: Similarity
messages: Belongs to the PhoH family.

265072:MFLA RS12355
gene id: 265072:MFLA_RS12355
uniprot id: Q1GYK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

265072:MFLA RS00185
gene id: 265072:MFLA_RS00185
uniprot id: Q1GXA9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

265072:MFLA RS08745
gene id: 265072:MFLA_RS08745
uniprot id: Q1H0L1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.

265072:MFLA RS10850
gene id: 265072:MFLA_RS10850
uniprot id: Q1GZF0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

265072:MFLA RS06630
gene id: 265072:MFLA_RS06630
uniprot id: Q1H1S4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Cell membrane
messages: Membrane

265072:MFLA RS10940
gene id: 265072:MFLA_RS10940
uniprot id: Q1GZD2
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

265072:MFLA RS09055
gene id: 265072:MFLA_RS09055
uniprot id: Q1H0F0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease gamma subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

265072:MFLA RS09655
gene id: 265072:MFLA_RS09655
uniprot id: Q1H031
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

265072:MFLA RS10860
gene id: 265072:MFLA_RS10860
uniprot id: Q1GZE8
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type I sub-subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The autoendoproteolytic cleavage occurs by a canonical serine protease mechanism, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain. During this reaction, the Ser that is part of the protease active site of the proenzyme becomes the pyruvoyl prosthetic group, which constitutes an essential element of the active site of the mature decarboxylase.

265072:MFLA RS01510
gene id: 265072:MFLA_RS01510
uniprot id: Q1H4M6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

265072:MFLA RS06125
gene id: 265072:MFLA_RS06125
uniprot id: Q1H222
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

265072:MFLA RS11755
gene id: 265072:MFLA_RS11755
uniprot id: Q1GYW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

265072:MFLA RS09985
gene id: 265072:MFLA_RS09985
uniprot id: Q1GZW5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

265072:MFLA RS10935
gene id: 265072:MFLA_RS10935
uniprot id: Q1GZD3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

265072:MFLA RS06105
gene id: 265072:MFLA_RS06105
uniprot id: Q1H225
names: Similarity
messages: Belongs to the UDP-galactopyranose/dTDP-fucopyranose mutase family.

265072:MFLA RS08045
gene id: 265072:MFLA_RS08045
uniprot id: Q1H0Z9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Cell inner membrane

265072:MFLA RS11655
gene id: 265072:MFLA_RS11655
uniprot id: Q1GYY9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

265072:MFLA RS11895
gene id: 265072:MFLA_RS11895
uniprot id: Q1GYU2
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

265072:MFLA RS06615
gene id: 265072:MFLA_RS06615
uniprot id: Q1H1S7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase bacterial subunit 4 family.
messages: Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron.
messages: Heterooctamer of two A chains, two B chains, two C chains and two D chains.
messages: Membrane

265072:MFLA RS08935
gene id: 265072:MFLA_RS08935
uniprot id: Q1H0H4
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

265072:MFLA RS12770
gene id: 265072:MFLA_RS12770
uniprot id: Q1GYB9
names: Similarity
messages: Belongs to the UbiH/COQ6 family.

265072:MFLA RS10155
gene id: 265072:MFLA_RS10155
uniprot id: Q1GZT1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

265072:MFLA RS08160
gene id: 265072:MFLA_RS08160
uniprot id: Q1H0X7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

265072:MFLA RS09390
gene id: 265072:MFLA_RS09390
uniprot id: Q1H084
names: Subcellular Location Annotation
messages: Membrane

265072:MFLA RS03030
gene id: 265072:MFLA_RS03030
uniprot id: Q1H3S6
names: Similarity
messages: Belongs to the DNA photolyase family.

265072:MFLA RS10000
gene id: 265072:MFLA_RS10000
uniprot id: Q1GZW2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of five rings (E,L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

265072:MFLA RS04145
gene id: 265072:MFLA_RS04145
uniprot id: Q1H358
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

265072:MFLA RS00085
gene id: 265072:MFLA_RS00085
uniprot id: Q1GX85
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

265072:MFLA RS06000
gene id: 265072:MFLA_RS06000
uniprot id: Q1H244
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HsdR family.
messages: Subunit R is required for both nuclease and ATPase activities, but not for modification.
messages: The type I restriction/modification system is composed of three polypeptides R, M and S.

265072:MFLA RS01335
gene id: 265072:MFLA_RS01335
uniprot id: Q1H4Q6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

265072:MFLA RS06005
gene id: 265072:MFLA_RS06005
uniprot id: Q1H243
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

265072:MFLA RS02585
gene id: 265072:MFLA_RS02585
uniprot id: Q1H411
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

265072:MFLA RS05760
gene id: 265072:MFLA_RS05760
uniprot id: Q1H293
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Slam family.
messages: Cell outer membrane
messages: Membrane

265072:MFLA RS08120
gene id: 265072:MFLA_RS08120
uniprot id: Q1H0Y5
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
messages: This function is generally fulfilled by the C-terminal part of HisG, which is missing in some bacteria such as this one.

265072:MFLA RS09965
gene id: 265072:MFLA_RS09965
uniprot id: Q1GZW9
names: Function
names: Similarity
messages: Belongs to the FlgN family.
messages: Required for the efficient initiation of filament assembly.

265072:MFLA RS01730
gene id: 265072:MFLA_RS01730
uniprot id: Q1H4I0
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

265072:MFLA RS11635
gene id: 265072:MFLA_RS11635
uniprot id: Q1GYZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

265072:MFLA RS11580
gene id: 265072:MFLA_RS11580
uniprot id: Q1GZ03
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

265072:MFLA RS03720
gene id: 265072:MFLA_RS03720
uniprot id: Q1H3E3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

265072:MFLA RS11910
gene id: 265072:MFLA_RS11910
uniprot id: Q1GYT9
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

265072:MFLA RS03310
gene id: 265072:MFLA_RS03310
uniprot id: Q1H3L8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

265072:MFLA RS00620
gene id: 265072:MFLA_RS00620
uniprot id: Q1GXH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

265072:MFLA RS10905
gene id: 265072:MFLA_RS10905
uniprot id: Q1GZD9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

265072:MFLA RS00695
gene id: 265072:MFLA_RS00695
uniprot id: Q1H534
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

265072:MFLA RS03560
gene id: 265072:MFLA_RS03560
uniprot id: Q1H3H4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

265072:MFLA RS07080
gene id: 265072:MFLA_RS07080
uniprot id: Q1H1I4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Monomer.

265072:MFLA RS07005
gene id: 265072:MFLA_RS07005
uniprot id: Q1H1J9
names: Similarity
messages: Belongs to the glycosyl hydrolase 57 family.

265072:MFLA RS12960
gene id: 265072:MFLA_RS12960
uniprot id: Q1GY81
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

265072:MFLA RS05720
gene id: 265072:MFLA_RS05720
uniprot id: Q1H2A0
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

265072:MFLA RS09865
gene id: 265072:MFLA_RS09865
uniprot id: Q1GZY9
names: Function
names: Similarity
messages: Belongs to the CheD family.
messages: Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.

265072:MFLA RS00040
gene id: 265072:MFLA_RS00040
uniprot id: Q1GXK3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

265072:MFLA RS12465
gene id: 265072:MFLA_RS12465
uniprot id: Q1GYI0
names: Similarity
messages: Belongs to the UPF0057 (PMP3) family.

265072:MFLA RS00035
gene id: 265072:MFLA_RS00035
uniprot id: Q1GXK4
names: Similarity
messages: Belongs to the ribosome association toxin RatA family.

265072:MFLA RS00465
gene id: 265072:MFLA_RS00465
uniprot id: Q1GXF0
names: Subcellular Location Annotation
messages: Membrane

265072:MFLA RS07185
gene id: 265072:MFLA_RS07185
uniprot id: Q1H1G5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inositol monophosphatase superfamily. CysQ family.
messages: Cell inner membrane
messages: Converts adenosine-3',5'-bisphosphate (PAP) to AMP.

265072:MFLA RS00990
gene id: 265072:MFLA_RS00990
uniprot id: Q1H4X6
names: Similarity
messages: Belongs to the Smg family.

265072:MFLA RS03985
gene id: 265072:MFLA_RS03985
uniprot id: Q1H389
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

265072:MFLA RS03285
gene id: 265072:MFLA_RS03285
uniprot id: Q1H3M3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

265072:MFLA RS09635
gene id: 265072:MFLA_RS09635
uniprot id: Q1H035
names: Similarity
messages: Belongs to the P(II) protein family.

265072:MFLA RS03130
gene id: 265072:MFLA_RS03130
uniprot id: Q1H3Q6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Part of the ABC transporter complex (TC 3.A.1.6.1) involved in sulfate/thiosulfate import.
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

265072:MFLA RS03360
gene id: 265072:MFLA_RS03360
uniprot id: Q1H3K8
names: Similarity
messages: Belongs to the ribosome association toxin RatA family.

265072:MFLA RS02070
gene id: 265072:MFLA_RS02070
uniprot id: Q1H4B4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

265072:MFLA RS01010
gene id: 265072:MFLA_RS01010
uniprot id: Q1H4X2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

265072:MFLA RS08730
gene id: 265072:MFLA_RS08730
uniprot id: Q1H0L4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

265072:MFLA RS09330
gene id: 265072:MFLA_RS09330
uniprot id: Q1H096
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

265072:MFLA RS05465
gene id: 265072:MFLA_RS05465
uniprot id: Q1H2F1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LapB family.
messages: Cell inner membrane
messages: Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane.

265072:MFLA RS13510
gene id: 265072:MFLA_RS13510
uniprot id: Q1GXX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

265072:MFLA RS01435
gene id: 265072:MFLA_RS01435
uniprot id: Q1H4P1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

265072:MFLA RS12740
gene id: 265072:MFLA_RS12740
uniprot id: Q1GYC5
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

265072:MFLA RS12480
gene id: 265072:MFLA_RS12480
uniprot id: Q1GYH7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).

265072:MFLA RS08850
gene id: 265072:MFLA_RS08850
uniprot id: Q1H0J2
names: Function
names: PTM
names: Similarity
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.

265072:MFLA RS03290
gene id: 265072:MFLA_RS03290
uniprot id: Q1H3M2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

265072:MFLA RS02530
gene id: 265072:MFLA_RS02530
uniprot id: Q1H422
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxH family.
messages: Binds 2 Mn(2+) ions per subunit in a binuclear metal center.
messages: Cell inner membrane
messages: Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

265072:MFLA RS11935
gene id: 265072:MFLA_RS11935
uniprot id: Q1GYT4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

265072:MFLA RS03085
gene id: 265072:MFLA_RS03085
uniprot id: Q1H3R5
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated protein Cas5 family. Subtype I-C/Dvulg subfamily.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).

265072:MFLA RS11970
gene id: 265072:MFLA_RS11970
uniprot id: Q1GYS7
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

265072:MFLA RS12450
gene id: 265072:MFLA_RS12450
uniprot id: Q1GYI3
names: Subcellular Location Annotation
messages: Secreted

265072:MFLA RS07415
gene id: 265072:MFLA_RS07415
uniprot id: Q1H1C1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
messages: Membrane

265072:MFLA RS10470
gene id: 265072:MFLA_RS10470
uniprot id: Q1GZL9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell inner membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

265072:MFLA RS14035
gene id: 265072:MFLA_RS14035
uniprot id: Q1GXM5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase C chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

265072:MFLA RS06410
gene id: 265072:MFLA_RS06410
uniprot id: Q1H1W6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

265072:MFLA RS07805
gene id: 265072:MFLA_RS07805
uniprot id: Q1H146
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

265072:MFLA RS11500
gene id: 265072:MFLA_RS11500
uniprot id: Q1GZ18
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetyltransferase family. ArgA subfamily.
messages: Cytoplasm
messages: In bacteria which possess the bifunctional enzyme ornithine acetyltransferase/N-acetylglutamate synthase (ArgJ), ArgA fulfills an anaplerotic role.

265072:MFLA RS09060
gene id: 265072:MFLA_RS09060
uniprot id: Q1H0E9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UreD family.
messages: Cytoplasm
messages: Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
messages: UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

265072:MFLA RS06865
gene id: 265072:MFLA_RS06865
uniprot id: Q1H1M7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

265072:MFLA RS07840
gene id: 265072:MFLA_RS07840
uniprot id: Q1H139
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

265072:MFLA RS07260
gene id: 265072:MFLA_RS07260
uniprot id: Q1H1F1
names: Similarity
messages: Belongs to the aminoglycoside phosphotransferase family.
messages: Belongs to the glycosyl hydrolase 13 family. TreS subfamily.

265072:MFLA RS13520
gene id: 265072:MFLA_RS13520
uniprot id: Q1GXX0
names: Subcellular Location Annotation
messages: Membrane

265072:MFLA RS05710
gene id: 265072:MFLA_RS05710
uniprot id: Q1H2A2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).

265072:MFLA RS11480
gene id: 265072:MFLA_RS11480
uniprot id: Q1GZ22
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

265072:MFLA RS08540
gene id: 265072:MFLA_RS08540
uniprot id: Q1H0Q2
names: Similarity
messages: Belongs to the IMPACT family.

265072:MFLA RS00265
gene id: 265072:MFLA_RS00265
uniprot id: Q1GXB3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family.
messages: Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.
messages: Cell inner membrane

265072:MFLA RS11705
gene id: 265072:MFLA_RS11705
uniprot id: Q1GYX9
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
messages: Part of the 50S ribosomal subunit.

265072:MFLA RS01590
gene id: 265072:MFLA_RS01590
uniprot id: Q1H4K9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

265072:MFLA RS09960
gene id: 265072:MFLA_RS09960
uniprot id: Q1GZX0
names: Similarity
messages: Belongs to the MotB family.

265072:MFLA RS04475
gene id: 265072:MFLA_RS04475
uniprot id: Q1H2K3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

265072:MFLA RS11290
gene id: 265072:MFLA_RS11290
uniprot id: Q1GZ62
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

265072:MFLA RS13955
gene id: 265072:MFLA_RS13955
uniprot id: Q1GXP0
names: Similarity
messages: Belongs to the glutamate synthase family.

265072:MFLA RS02790
gene id: 265072:MFLA_RS02790
uniprot id: Q1H3X4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatB family.
messages: Cell inner membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

265072:MFLA RS01800
gene id: 265072:MFLA_RS01800
uniprot id: Q1H4G6
names: Similarity
messages: Belongs to the transcriptional regulatory Fis family.

265072:MFLA RS09605
gene id: 265072:MFLA_RS09605
uniprot id: Q1H041
names: Similarity
messages: Belongs to the YciI family.

265072:MFLA RS08130
gene id: 265072:MFLA_RS08130
uniprot id: Q1H0Y3
names: Function
names: Similarity
messages: Belongs to the band 7/mec-2 family. HflC subfamily.
messages: HflC and HflK could regulate a protease.

265072:MFLA RS09515
gene id: 265072:MFLA_RS09515
uniprot id: Q1H059
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

265072:MFLA RS08570
gene id: 265072:MFLA_RS08570
uniprot id: Q1H0P6
names: Similarity
messages: Belongs to the PAPS reductase family. CysD subfamily.

265072:MFLA RS08180
gene id: 265072:MFLA_RS08180
uniprot id: Q1H0X3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
messages: Cytoplasm

265072:MFLA RS00115
gene id: 265072:MFLA_RS00115
uniprot id: Q1GX90
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

265072:MFLA RS08665
gene id: 265072:MFLA_RS08665
uniprot id: Q1H0M7
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

265072:MFLA RS05665
gene id: 265072:MFLA_RS05665
uniprot id: Q1H2B1
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSP33 family.
messages: Cytoplasm
messages: Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.
messages: Under oxidizing conditions two disulfide bonds are formed involving the reactive cysteines. Under reducing conditions zinc is bound to the reactive cysteines and the protein is inactive.

265072:MFLA RS08690
gene id: 265072:MFLA_RS08690
uniprot id: Q1H0M2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

265072:MFLA RS00125
gene id: 265072:MFLA_RS00125
uniprot id: Q1GX99
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

265072:MFLA RS02565
gene id: 265072:MFLA_RS02565
uniprot id: Q1H415
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

265072:MFLA RS08590
gene id: 265072:MFLA_RS08590
uniprot id: Q1H0P2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

265072:MFLA RS09540
gene id: 265072:MFLA_RS09540
uniprot id: Q1H054
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family.
messages: Cytoplasm
messages: Homotrimer.

265072:MFLA RS12455
gene id: 265072:MFLA_RS12455
uniprot id: Q1GYI2
names: Subcellular Location Annotation
messages: Membrane

265072:MFLA RS11570
gene id: 265072:MFLA_RS11570
uniprot id: Q1GZ05
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsQ/DivIB family. FtsQ subfamily.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly.
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

265072:MFLA RS11555
gene id: 265072:MFLA_RS11555
uniprot id: Q1GZ08
names: Function
names: Similarity
messages: Belongs to the LpxC family.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.

265072:MFLA RS03700
gene id: 265072:MFLA_RS03700
uniprot id: Q1H3E7
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

265072:MFLA RS02500
gene id: 265072:MFLA_RS02500
uniprot id: Q1H427
names: Subcellular Location Annotation
messages: Membrane

265072:MFLA RS10265
gene id: 265072:MFLA_RS10265
uniprot id: Q1GZR0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

265072:MFLA RS09325
gene id: 265072:MFLA_RS09325
uniprot id: Q1H097
names: Similarity
messages: Belongs to the WrbA family.

265072:MFLA RS06675
gene id: 265072:MFLA_RS06675
uniprot id: Q1H1R4
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

265072:MFLA RS00165
gene id: 265072:MFLA_RS00165
uniprot id: Q1GX91
names: Function
names: Similarity
messages: Belongs to the uroporphyrinogen-III synthase family.
messages: Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.

265072:MFLA RS09675
gene id: 265072:MFLA_RS09675
uniprot id: Q1H027
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

265072:MFLA RS04150
gene id: 265072:MFLA_RS04150
uniprot id: Q1H357
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA.
messages: Cytoplasm
messages: Homodimer.

265072:MFLA RS06145
gene id: 265072:MFLA_RS06145
uniprot id: Q1H218
names: Subcellular Location Annotation
messages: Membrane

265072:MFLA RS01410
gene id: 265072:MFLA_RS01410
uniprot id: Q1H4P6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

265072:MFLA RS10760
gene id: 265072:MFLA_RS10760
uniprot id: Q1GZG8
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

265072:MFLA RS11330
gene id: 265072:MFLA_RS11330
uniprot id: Q1GZ54
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

265072:MFLA RS08595
gene id: 265072:MFLA_RS08595
uniprot id: Q1H0P1
names: Similarity
messages: Belongs to the CFA/CMAS family.

265072:MFLA RS08720
gene id: 265072:MFLA_RS08720
uniprot id: Q1H0L6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

265072:MFLA RS09980
gene id: 265072:MFLA_RS09980
uniprot id: Q1GZW6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod.

265072:MFLA RS07960
gene id: 265072:MFLA_RS07960
uniprot id: Q1H117
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

265072:MFLA RS09525
gene id: 265072:MFLA_RS09525
uniprot id: Q1H057
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

265072:MFLA RS05855
gene id: 265072:MFLA_RS05855
uniprot id: Q1H275
names: Similarity
messages: Belongs to the ribosome association toxin RatA family.

265072:MFLA RS08715
gene id: 265072:MFLA_RS08715
uniprot id: Q1H0L7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

265072:MFLA RS00760
gene id: 265072:MFLA_RS00760
uniprot id: Q1H521
names: Function
names: Similarity
messages: Belongs to the RapZ-like family.
messages: Displays ATPase and GTPase activities.

265072:MFLA RS03930
gene id: 265072:MFLA_RS03930
uniprot id: Q1H3A0
names: Function
names: Similarity
names: Subunit
messages: Catalyzes the ADP transfer from ATP to D-glycero-beta-D-manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose.
messages: Catalyzes the phosphorylation of D-glycero-D-manno-heptose 7-phosphate at the C-1 position to selectively form D-glycero-beta-D-manno-heptose-1,7-bisphosphate.
messages: Homodimer.
messages: In the C-terminal section; belongs to the cytidylyltransferase family.
messages: In the N-terminal section; belongs to the carbohydrate kinase PfkB family.

265072:MFLA RS02920
gene id: 265072:MFLA_RS02920
uniprot id: Q1H3U8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

265072:MFLA RS11015
gene id: 265072:MFLA_RS11015
uniprot id: Q1GZB7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Monomer.

265072:MFLA RS12525
gene id: 265072:MFLA_RS12525
uniprot id: Q1GYG8
names: Similarity
messages: Belongs to the dGTPase family. Type 2 subfamily.

265072:MFLA RS11975
gene id: 265072:MFLA_RS11975
uniprot id: Q1GYS6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvB family.
messages: Forms a complex with RuvA.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.

265072:MFLA RS01985
gene id: 265072:MFLA_RS01985
uniprot id: Q1H4D0
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

265072:MFLA RS12640
gene id: 265072:MFLA_RS12640
uniprot id: Q1GYE5
names: Similarity
messages: Belongs to the class-D beta-lactamase family.

265072:MFLA RS00885
gene id: 265072:MFLA_RS00885
uniprot id: Q1H4Z7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

265072:MFLA RS01940
gene id: 265072:MFLA_RS01940
uniprot id: Q1H4D9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
messages: Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.
messages: Cytoplasm
messages: Homodimer.

265072:MFLA RS08145
gene id: 265072:MFLA_RS08145
uniprot id: Q1H0Y0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

265072:MFLA RS08525
gene id: 265072:MFLA_RS08525
uniprot id: Q1H0Q5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FTR family.
messages: Catalyzes the transfer of a formyl group from 5-formyl tetrahydromethanopterin (5-formyl-H(4)MPT) to methanofuran (MFR) to produce formylmethanofuran (formyl-MFR) and tetrahydromethanopterin (H(4)MPT).
messages: Cytoplasm
messages: Homotetramer.

265072:MFLA RS13280
gene id: 265072:MFLA_RS13280
uniprot id: Q1GY16
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

265072:MFLA RS01750
gene id: 265072:MFLA_RS01750
uniprot id: Q1H4H6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.

265072:MFLA RS02225
gene id: 265072:MFLA_RS02225
uniprot id: Q1H484
names: Similarity
messages: Belongs to the P(II) protein family.

265072:MFLA RS04770
gene id: 265072:MFLA_RS04770
uniprot id: Q1H2E4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the R-transferase family. Bpt subfamily.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate.

265072:MFLA RS10535
gene id: 265072:MFLA_RS10535
uniprot id: Q1GZK7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

265072:MFLA RS01880
gene id: 265072:MFLA_RS01880
uniprot id: Q1H4F1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

265072:MFLA RS10785
gene id: 265072:MFLA_RS10785
uniprot id: Q1GZG3
names: Similarity
messages: Belongs to the GSP E family.

265072:MFLA RS10960
gene id: 265072:MFLA_RS10960
uniprot id: Q1GZC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

265072:MFLA RS14020
gene id: 265072:MFLA_RS14020
uniprot id: Q1GXM8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

265072:MFLA RS06635
gene id: 265072:MFLA_RS06635
uniprot id: Q1H1S3
names: Similarity
messages: Belongs to the protease inhibitor I11 (ecotin) family.

265072:MFLA RS04885
gene id: 265072:MFLA_RS04885
uniprot id: Q1H2C1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. RhlE subfamily.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in ribosome assembly. Has RNA-dependent ATPase activity and unwinds double-stranded RNA.

265072:MFLA RS09905
gene id: 265072:MFLA_RS09905
uniprot id: Q1GZY1
names: Similarity
messages: Belongs to the MotB family.

265072:MFLA RS00360
gene id: 265072:MFLA_RS00360
uniprot id: Q1GXD5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

265072:MFLA RS10210
gene id: 265072:MFLA_RS10210
uniprot id: Q1GZS1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

265072:MFLA RS04925
gene id: 265072:MFLA_RS04925
uniprot id: Q1H2B3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose 5-phosphate isomerase family.
messages: Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
messages: Homodimer.

265072:MFLA RS03250
gene id: 265072:MFLA_RS03250
uniprot id: Q1H3N0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterioferritin family.
messages: Iron-storage protein.
messages: Oligomer of 24 subunits, arranged as 12 dimers, that are packed together to form an approximately spherical molecule with a central cavity, in which large amounts of iron can be deposited.

265072:MFLA RS11665
gene id: 265072:MFLA_RS11665
uniprot id: Q1GYY7
names: Similarity
messages: Belongs to the UPF0102 family.

265072:MFLA RS01405
gene id: 265072:MFLA_RS01405
uniprot id: Q1H4P7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

265072:MFLA RS07990
gene id: 265072:MFLA_RS07990
uniprot id: Q1H111
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

265072:MFLA RS10205
gene id: 265072:MFLA_RS10205
uniprot id: Q1GZS2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

265072:MFLA RS10915
gene id: 265072:MFLA_RS10915
uniprot id: Q1GZD7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

265072:MFLA RS10030
gene id: 265072:MFLA_RS10030
uniprot id: Q1GZV6
names: Subcellular Location Annotation
messages: Secreted

265072:MFLA RS01845
gene id: 265072:MFLA_RS01845
uniprot id: Q1H4F8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
messages: Single-chain monomer with multiple functions.

265072:MFLA RS07850
gene id: 265072:MFLA_RS07850
uniprot id: Q1H137
names: Activity Regulation
names: Caution
names: Domain
names: Function
names: Similarity
messages: Belongs to the GlnD family.
messages: Has four distinct domains: an N-terminal nucleotidyltransferase (NT) domain responsible for UTase activity, a central HD domain that encodes UR activity, and two C-terminal ACT domains that seem to have a role in glutamine sensing.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism.
messages: Uridylyltransferase (UTase) activity is inhibited by glutamine, while glutamine activates uridylyl-removing (UR) activity.

265072:MFLA RS12360
gene id: 265072:MFLA_RS12360
uniprot id: Q1GYK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP G family.
messages: Cell inner membrane
messages: Membrane

265072:MFLA RS08550
gene id: 265072:MFLA_RS08550
uniprot id: Q1H0Q0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

265072:MFLA RS11050
gene id: 265072:MFLA_RS11050
uniprot id: Q1GZB0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

265072:MFLA RS09045
gene id: 265072:MFLA_RS09045
uniprot id: Q1H0F2
names: Cofactor
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
messages: Binds 2 nickel ions per subunit.
messages: Carboxylation allows a single lysine to coordinate two nickel ions.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

265072:MFLA RS00565
gene id: 265072:MFLA_RS00565
uniprot id: Q1GXH0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

265072:MFLA RS06760
gene id: 265072:MFLA_RS06760
uniprot id: Q1H1P7
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

265072:MFLA RS10025
gene id: 265072:MFLA_RS10025
uniprot id: Q1GZV7
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

265072:MFLA RS01790
gene id: 265072:MFLA_RS01790
uniprot id: Q1H4G8
names: Similarity
messages: Belongs to the GARS family.

265072:MFLA RS09925
gene id: 265072:MFLA_RS09925
uniprot id: Q1GZX7
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FlhD family.
messages: Cytoplasm
messages: Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways.
messages: Homodimer; disulfide-linked. Forms a heterohexamer composed of two FlhC and four FlhD subunits. Each FlhC binds a FlhD dimer, forming a heterotrimer, and a hexamer assembles by dimerization of two heterotrimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The C-terminal region contains a putative helix-turn-helix (HTH) motif, suggesting that this region may bind DNA.

265072:MFLA RS11170
gene id: 265072:MFLA_RS11170
uniprot id: Q1GZ85
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecB family.
messages: Cytoplasm
messages: Homotetramer, a dimer of dimers. One homotetramer interacts with 1 SecA dimer.
messages: One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.

265072:MFLA RS12670
gene id: 265072:MFLA_RS12670
uniprot id: Q1GYD9
names: Subcellular Location Annotation
messages: Membrane

265072:MFLA RS00345
gene id: 265072:MFLA_RS00345
uniprot id: Q1GXD8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

265072:MFLA RS06970
gene id: 265072:MFLA_RS06970
uniprot id: Q1H1K6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MntP (TC 9.B.29) family.
messages: Cell inner membrane
messages: Probably functions as a manganese efflux pump.

265072:MFLA RS11040
gene id: 265072:MFLA_RS11040
uniprot id: Q1GZB2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

265072:MFLA RS07810
gene id: 265072:MFLA_RS07810
uniprot id: Q1H145
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).

265072:MFLA RS02130
gene id: 265072:MFLA_RS02130
uniprot id: Q1H4A2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

265072:MFLA RS06620
gene id: 265072:MFLA_RS06620
uniprot id: Q1H1S6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron.
messages: Heterooctamer of two A chains, two B chains, two C chains and two D chains.
messages: Membrane

265072:MFLA RS04875
gene id: 265072:MFLA_RS04875
uniprot id: Q1H2C3
names: Similarity
messages: Belongs to the UPF0178 family.

265072:MFLA RS01075
gene id: 265072:MFLA_RS01075
uniprot id: Q1H4V8
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

265072:MFLA RS06465
gene id: 265072:MFLA_RS06465
uniprot id: Q1H1V6
names: Similarity
names: Subunit
messages: Belongs to the MoaE family.
messages: Heterotetramer of 2 MoaD subunits and 2 MoaE subunits. Also stable as homodimer. The enzyme changes between these two forms during catalysis.

265072:MFLA RS09130
gene id: 265072:MFLA_RS09130
uniprot id: Q1H0D4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

265072:MFLA RS12025
gene id: 265072:MFLA_RS12025
uniprot id: Q1GYR6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RuvC family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.

265072:MFLA RS05930
gene id: 265072:MFLA_RS05930
uniprot id: Q1H259
names: Subcellular Location Annotation
messages: Membrane

265072:MFLA RS06950
gene id: 265072:MFLA_RS06950
uniprot id: Q1H1L0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

265072:MFLA RS00960
gene id: 265072:MFLA_RS00960
uniprot id: Q1H4Y2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Cytoplasm
messages: Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.

265072:MFLA RS13350
gene id: 265072:MFLA_RS13350
uniprot id: Q1GY02
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

265072:MFLA RS11495
gene id: 265072:MFLA_RS11495
uniprot id: Q1GZ19
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

265072:MFLA RS03675
gene id: 265072:MFLA_RS03675
uniprot id: Q1H3F2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CpxP/Spy family.
messages: Periplasm

265072:MFLA RS06245
gene id: 265072:MFLA_RS06245
uniprot id: Q1H1Z9
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

265072:MFLA RS10715
gene id: 265072:MFLA_RS10715
uniprot id: Q1GZH7
names: Subcellular Location Annotation
messages: Membrane

265072:MFLA RS06775
gene id: 265072:MFLA_RS06775
uniprot id: Q1H1P4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

265072:MFLA RS12540
gene id: 265072:MFLA_RS12540
uniprot id: Q1GYG5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial secretin family. PilQ subfamily.
messages: Cell outer membrane
messages: Homododecamer. Tetramer of trimer.
messages: Required for type IV pilus biogenesis and competence. Could function as a pore for exit of the pilus but also as a channel for entry of heme and antimicrobial agents and uptake of transforming DNA.

265072:MFLA RS04390
gene id: 265072:MFLA_RS04390
uniprot id: Q1H2M0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate.
messages: Cytoplasm

265072:MFLA RS06900
gene id: 265072:MFLA_RS06900
uniprot id: Q1H1M0
names: Subcellular Location Annotation
messages: Secreted

265072:MFLA RS04635
gene id: 265072:MFLA_RS04635
uniprot id: Q1H2H1
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

265072:MFLA RS10100
gene id: 265072:MFLA_RS10100
uniprot id: Q1GZU2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliF family.
messages: Membrane
messages: The M ring may be actively involved in energy transduction.

265072:MFLA RS00675
gene id: 265072:MFLA_RS00675
uniprot id: Q1GXJ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the serine/threonine dehydratase family.
messages: Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
messages: Homotetramer.

265072:MFLA RS13085
gene id: 265072:MFLA_RS13085
uniprot id: Q1GY55
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

265072:MFLA RS06405
gene id: 265072:MFLA_RS06405
uniprot id: Q1H1W7
names: Subcellular Location Annotation
messages: Membrane

265072:MFLA RS00295
gene id: 265072:MFLA_RS00295
uniprot id: Q1GXC7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HesB/IscA family.
messages: Binds 1 iron-sulfur cluster per subunit.
messages: Homodimer.
messages: Required for insertion of 4Fe-4S clusters.

265072:MFLA RS00245
gene id: 265072:MFLA_RS00245
uniprot id: Q1GXB7
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

265072:MFLA RS03070
gene id: 265072:MFLA_RS03070
uniprot id: Q1H3R8
names: Function
names: Similarity
messages: Belongs to the HPPK family.
messages: Catalyzes the transfer of pyrophosphate from adenosine triphosphate (ATP) to 6-hydroxymethyl-7,8-dihydropterin, an enzymatic step in folate biosynthesis pathway.

265072:MFLA RS10020
gene id: 265072:MFLA_RS10020
uniprot id: Q1GZV8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Flagellum-specific muramidase which hydrolyzes the peptidoglycan layer to assemble the rod structure in the periplasmic space.
messages: In the C-terminal section; belongs to the glycosyl hydrolase 73 family.
messages: In the N-terminal section; belongs to the FlgJ family.
messages: Periplasm

265072:MFLA RS12735
gene id: 265072:MFLA_RS12735
uniprot id: Q1GYC6
names: Function
names: Similarity
messages: Belongs to the RlpA family.
messages: Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.

265072:MFLA RS03865
gene id: 265072:MFLA_RS03865
uniprot id: Q1H3B4
names: Function
names: Similarity
messages: Belongs to the protein kinase superfamily. KdkA/rfaP family.
messages: Catalyzes the phosphorylation of heptose(I) of the outer membrane lipopolysaccharide core.

265072:MFLA RS11475
gene id: 265072:MFLA_RS11475
uniprot id: Q1GZ23
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

265072:MFLA RS04690
gene id: 265072:MFLA_RS04690
uniprot id: Q1H2G0
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-I family.

265072:MFLA RS04115
gene id: 265072:MFLA_RS04115
uniprot id: Q1H364
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HscB family.
messages: Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA.
messages: Interacts with HscA and stimulates its ATPase activity.

265072:MFLA RS13430
gene id: 265072:MFLA_RS13430
uniprot id: Q1GXY7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

265072:MFLA RS08495
gene id: 265072:MFLA_RS08495
uniprot id: Q9RQ04
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCH family.
messages: Catalyzes the hydrolysis of methenyl-H(4)MPT(+) to 5-formyl-H(4)MPT.
messages: Cytoplasm

265072:MFLA RS03155
gene id: 265072:MFLA_RS03155
uniprot id: Q1H3Q0
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
messages: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.

265072:MFLA RS09560
gene id: 265072:MFLA_RS09560
uniprot id: Q1H050
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmB subfamily.
messages: Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue.

265072:MFLA RS02610
gene id: 265072:MFLA_RS02610
uniprot id: Q1H406
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

265072:MFLA RS05230
gene id: 265072:MFLA_RS05230
uniprot id: Q1H2J8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

265072:MFLA RS11455
gene id: 265072:MFLA_RS11455
uniprot id: Q1GZ28
names: Similarity
messages: Belongs to the SAICAR synthetase family.

265072:MFLA RS07430
gene id: 265072:MFLA_RS07430
uniprot id: Q1H1B8
names: Similarity
messages: Belongs to the bacterial PQQ dehydrogenase family.

265072:MFLA RS05175
gene id: 265072:MFLA_RS05175
uniprot id: Q1H2K9
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

265072:MFLA RS03715
gene id: 265072:MFLA_RS03715
uniprot id: Q1H3E4
names: Cofactor
names: Function
messages: Accepts electrons from ETF and reduces ubiquinone.
messages: Binds 1 [4Fe-4S] cluster.

265072:MFLA RS12730
gene id: 265072:MFLA_RS12730
uniprot id: Q1GYC7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. MrdB/RodA subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell wall elongation.

265072:MFLA RS00250
gene id: 265072:MFLA_RS00250
uniprot id: Q1GXB6
names: Similarity
messages: Belongs to the RutC family.

265072:MFLA RS04270
gene id: 265072:MFLA_RS04270
uniprot id: Q1H2P4
names: Function
names: Similarity
messages: Belongs to the phage GPA family.
messages: Possible endonuclease which induces a single-strand cut and initiates DNA replication.

265072:MFLA RS11780
gene id: 265072:MFLA_RS11780
uniprot id: Q1GYW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

265072:MFLA RS07200
gene id: 265072:MFLA_RS07200
uniprot id: Q1H1G2
names: Subcellular Location Annotation
messages: Cytoplasm

265072:MFLA RS10065
gene id: 265072:MFLA_RS10065
uniprot id: Q1GZU9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: Cell inner membrane
messages: FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

265072:MFLA RS08530
gene id: 265072:MFLA_RS08530
uniprot id: Q1H0Q4
names: Similarity
messages: Belongs to the FwdC/FmdC family.

265072:MFLA RS02970
gene id: 265072:MFLA_RS02970
uniprot id: Q1H3T8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

265072:MFLA RS02875
gene id: 265072:MFLA_RS02875
uniprot id: Q1H3V6
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

265072:MFLA RS04330
gene id: 265072:MFLA_RS04330
uniprot id: Q1H2N2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

265072:MFLA RS05450
gene id: 265072:MFLA_RS05450
uniprot id: Q1H2F4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.

265072:MFLA RS03960
gene id: 265072:MFLA_RS03960
uniprot id: Q1H394
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

265072:MFLA RS05755
gene id: 265072:MFLA_RS05755
uniprot id: Q1H294
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LolA family.
messages: Monomer.
messages: Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).
messages: Periplasm

265072:MFLA RS13090
gene id: 265072:MFLA_RS13090
uniprot id: Q1GY54
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

265072:MFLA RS02575
gene id: 265072:MFLA_RS02575
uniprot id: Q1H413
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

265072:MFLA RS03145
gene id: 265072:MFLA_RS03145
uniprot id: Q1H3Q2
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

265072:MFLA RS13600
gene id: 265072:MFLA_RS13600
uniprot id: Q1GXV5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

265072:MFLA RS04830
gene id: 265072:MFLA_RS04830
uniprot id: Q1H2D2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell inner membrane
messages: Membrane

265072:MFLA RS12575
gene id: 265072:MFLA_RS12575
uniprot id: Q1GYF8
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

265072:MFLA RS10005
gene id: 265072:MFLA_RS10005
uniprot id: Q1GZW1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

265072:MFLA RS01525
gene id: 265072:MFLA_RS01525
uniprot id: Q1H4M3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

265072:MFLA RS07590
gene id: 265072:MFLA_RS07590
uniprot id: Q1H190
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

265072:MFLA RS03260
gene id: 265072:MFLA_RS03260
uniprot id: Q1H3M8
names: Caution
names: Function
names: Similarity
messages: Belongs to the globin family. Two-domain flavohemoproteins subfamily.
messages: In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
messages: Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

265072:MFLA RS09625
gene id: 265072:MFLA_RS09625
uniprot id: Q1H037
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oxidase-dependent Fe transporter (OFeT) (TC 9.A.10.1) family.
messages: Membrane

265072:MFLA RS07530
gene id: 265072:MFLA_RS07530
uniprot id: Q1H1A2
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Although this enzyme belongs to the family of MTA phosphorylases based on sequence homology, it has been shown that conserved amino acid substitutions in the substrate binding pocket convert the substrate specificity of this enzyme from 6-aminopurines to 6-oxopurines.
messages: Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
messages: Homohexamer. Dimer of a homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Purine nucleoside phosphorylase which is highly specific for 6-oxopurine nucleosides. Cleaves guanosine or inosine to respective bases and sugar-1-phosphate molecules. Involved in purine salvage.

265072:MFLA RS04700
gene id: 265072:MFLA_RS04700
uniprot id: Q1H2F8
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

265072:MFLA RS01610
gene id: 265072:MFLA_RS01610
uniprot id: Q1H4K5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

265072:MFLA RS05920
gene id: 265072:MFLA_RS05920
uniprot id: Q1H261
names: Similarity
messages: Belongs to the peptidase S1C family.

265072:MFLA RS01550
gene id: 265072:MFLA_RS01550
uniprot id: Q1H4L8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

265072:MFLA RS10050
gene id: 265072:MFLA_RS10050
uniprot id: Q1GZV2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliP/MopC/SpaP family.
messages: Cell membrane
messages: Membrane
messages: Plays a role in the flagellum-specific transport system.

265072:MFLA RS05535
gene id: 265072:MFLA_RS05535
uniprot id: Q1H2D7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

265072:MFLA RS10085
gene id: 265072:MFLA_RS10085
uniprot id: Q1GZU5
names: Subcellular Location Annotation
messages: Cytoplasm

265072:MFLA RS09455
gene id: 265072:MFLA_RS09455
uniprot id: Q1H071
names: Similarity
messages: Belongs to the YkuD family.

265072:MFLA RS06545
gene id: 265072:MFLA_RS06545
uniprot id: Q1H1U0
names: Similarity
messages: Belongs to the UDPGP type 2 family.

265072:MFLA RS09420
gene id: 265072:MFLA_RS09420
uniprot id: Q1H078
names: Subcellular Location Annotation
messages: Membrane

265072:MFLA RS12110
gene id: 265072:MFLA_RS12110
uniprot id: Q1GYP8
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

265072:MFLA RS02990
gene id: 265072:MFLA_RS02990
uniprot id: Q1H3T4
names: Similarity
messages: Belongs to the UPF0307 family.

265072:MFLA RS01570
gene id: 265072:MFLA_RS01570
uniprot id: Q1H4L3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

265072:MFLA RS10865
gene id: 265072:MFLA_RS10865
uniprot id: Q1GZE7
names: Function
names: Similarity
messages: Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
messages: Belongs to the Nudix hydrolase family. RppH subfamily.

265072:MFLA RS04105
gene id: 265072:MFLA_RS04105
uniprot id: Q1H366
names: Similarity
messages: Belongs to the adrenodoxin/putidaredoxin family.

265072:MFLA RS07730
gene id: 265072:MFLA_RS07730
uniprot id: Q1H161
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

265072:MFLA RS05120
gene id: 265072:MFLA_RS05120
uniprot id: Q1H2M0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate.
messages: Cytoplasm

265072:MFLA RS02975
gene id: 265072:MFLA_RS02975
uniprot id: Q1H3T7
names: Subcellular Location Annotation
messages: Membrane

265072:MFLA RS09680
gene id: 265072:MFLA_RS09680
uniprot id: Q1H026
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thioester dehydratase family. FabA subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP. Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length.

265072:MFLA RS01440
gene id: 265072:MFLA_RS01440
uniprot id: Q1H4P0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

265072:MFLA RS07615
gene id: 265072:MFLA_RS07615
uniprot id: Q1H185
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

265072:MFLA RS01660
gene id: 265072:MFLA_RS01660
uniprot id: Q1H4J5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
messages: Membrane

265072:MFLA RS04110
gene id: 265072:MFLA_RS04110
uniprot id: Q1H365
names: Function
names: Similarity
messages: Belongs to the heat shock protein 70 family.
messages: Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB.

265072:MFLA RS05415
gene id: 265072:MFLA_RS05415
uniprot id: Q1H2G1
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

265072:MFLA RS08705
gene id: 265072:MFLA_RS08705
uniprot id: Q1H0L9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.

265072:MFLA RS00965
gene id: 265072:MFLA_RS00965
uniprot id: Q1H4Y1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell inner membrane
messages: Membrane

265072:MFLA RS11650
gene id: 265072:MFLA_RS11650
uniprot id: Q1GYZ0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Homodimer.

265072:MFLA RS05970
gene id: 265072:MFLA_RS05970
uniprot id: Q1H250
names: Subcellular Location Annotation
messages: Membrane

265072:MFLA RS03015
gene id: 265072:MFLA_RS03015
uniprot id: Q1H3S9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

265072:MFLA RS12705
gene id: 265072:MFLA_RS12705
uniprot id: Q1GYD2
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

265072:MFLA RS13635
gene id: 265072:MFLA_RS13635
uniprot id: Q1GXU8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

265072:MFLA RS13210
gene id: 265072:MFLA_RS13210
uniprot id: Q1GY30
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

265072:MFLA RS01415
gene id: 265072:MFLA_RS01415
uniprot id: Q1H4P5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

265072:MFLA RS00110
gene id: 265072:MFLA_RS00110
uniprot id: Q1GX86
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

265072:MFLA RS11980
gene id: 265072:MFLA_RS11980
uniprot id: Q1GYS5
names: Similarity
messages: Belongs to the shaker potassium channel beta subunit family.

265072:MFLA RS11060
gene id: 265072:MFLA_RS11060
uniprot id: Q1GZA8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. Carboxylesterase BioH family.
messages: Cytoplasm
messages: Monomer.
messages: The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters.

265072:MFLA RS11880
gene id: 265072:MFLA_RS11880
uniprot id: Q1GYU5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

265072:MFLA RS00530
gene id: 265072:MFLA_RS00530
uniprot id: Q1GXF9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell inner membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Membrane

265072:MFLA RS13035
gene id: 265072:MFLA_RS13035
uniprot id: Q1GY65
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

265072:MFLA RS02880
gene id: 265072:MFLA_RS02880
uniprot id: Q1H3V5
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

265072:MFLA RS12170
gene id: 265072:MFLA_RS12170
uniprot id: Q1GYN9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

265072:MFLA RS08115
gene id: 265072:MFLA_RS08115
uniprot id: Q1H0Y6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

265072:MFLA RS01945
gene id: 265072:MFLA_RS01945
uniprot id: Q1H4D8
names: Similarity
messages: Belongs to the peptidase S13 family.

265072:MFLA RS10275
gene id: 265072:MFLA_RS10275
uniprot id: Q1GZQ8
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 2 family.

265072:MFLA RS04645
gene id: 265072:MFLA_RS04645
uniprot id: Q9RAM7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

265072:MFLA RS05420
gene id: 265072:MFLA_RS05420
uniprot id: Q1H2G0
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-I family.

265072:MFLA RS01490
gene id: 265072:MFLA_RS01490
uniprot id: Q1H4N0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

265072:MFLA RS00745
gene id: 265072:MFLA_RS00745
uniprot id: Q1H524
names: Function
names: Similarity
messages: Belongs to the sigma-54 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

265072:MFLA RS07435
gene id: 265072:MFLA_RS07435
uniprot id: Q1H1B7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

265072:MFLA RS03045
gene id: 265072:MFLA_RS03045
uniprot id: Q1H3S3
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

265072:MFLA RS06265
gene id: 265072:MFLA_RS06265
uniprot id: Q1H1Z5
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.

265072:MFLA RS11960
gene id: 265072:MFLA_RS11960
uniprot id: Q1GYS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

265072:MFLA RS09235
gene id: 265072:MFLA_RS09235
uniprot id: Q1H0B6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

265072:MFLA RS02665
gene id: 265072:MFLA_RS02665
uniprot id: Q1H3Z5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

265072:MFLA RS01265
gene id: 265072:MFLA_RS01265
uniprot id: Q1H4S0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm

265072:MFLA RS10720
gene id: 265072:MFLA_RS10720
uniprot id: Q1GZH6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3.A.1.125) family.
messages: Cell inner membrane
messages: Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.
messages: The complex is composed of two ATP-binding proteins (LolD) and two transmembrane proteins (LolC and LolE).

265072:MFLA RS01515
gene id: 265072:MFLA_RS01515
uniprot id: Q1H4M5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

265072:MFLA RS03695
gene id: 265072:MFLA_RS03695
uniprot id: Q1H3E8
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

265072:MFLA RS06225
gene id: 265072:MFLA_RS06225
uniprot id: Q1H203
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

265072:MFLA RS08155
gene id: 265072:MFLA_RS08155
uniprot id: Q1H0X8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

265072:MFLA RS03110
gene id: 265072:MFLA_RS03110
uniprot id: Q1H3R0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

265072:MFLA RS05480
gene id: 265072:MFLA_RS05480
uniprot id: Q1H2E8
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS1 family.
messages: Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.

265072:MFLA RS10950
gene id: 265072:MFLA_RS10950
uniprot id: Q1GZD0
names: Subcellular Location Annotation
messages: Cytoplasm

265072:MFLA RS08325
gene id: 265072:MFLA_RS08325
uniprot id: Q1H0U4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. RlmB subfamily.
messages: Cytoplasm
messages: Specifically methylates the ribose of guanosine 2251 in 23S rRNA.

265072:MFLA RS05430
gene id: 265072:MFLA_RS05430
uniprot id: Q1H2F8
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

265072:MFLA RS01310
gene id: 265072:MFLA_RS01310
uniprot id: Q1H4R1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRA-CH family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
messages: Cytoplasm
messages: Homodimer.

265072:MFLA RS14090
gene id: 265072:MFLA_RS14090
uniprot id: Q1GXL3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

265072:MFLA RS01705
gene id: 265072:MFLA_RS01705
uniprot id: Q1H4I5
names: Subcellular Location Annotation
messages: Membrane

265072:MFLA RS11965
gene id: 265072:MFLA_RS11965
uniprot id: Q1GYS8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbB/TolQ family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

265072:MFLA RS05785
gene id: 265072:MFLA_RS05785
uniprot id: Q1H288
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: In the C-terminal section; belongs to the transglycosylase Slt family.
messages: In the N-terminal section; belongs to the bacterial solute-binding protein 3 family.
messages: Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella.
messages: The N-terminal domain does not have lytic activity and probably modulates enzymatic activity. The C-terminal domain is the catalytic active domain.

265072:MFLA RS11270
gene id: 265072:MFLA_RS11270
uniprot id: Q1GZ66
names: Function
names: Similarity
messages: Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PSRP subfamily.
messages: Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation.

265072:MFLA RS10965
gene id: 265072:MFLA_RS10965
uniprot id: Q1GZC7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbC subfamily.
messages: Periplasm
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process.

265072:MFLA RS13900
gene id: 265072:MFLA_RS13900
uniprot id: Q1GXQ0
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

265072:MFLA RS12820
gene id: 265072:MFLA_RS12820
uniprot id: Q1GYA9
names: Similarity
messages: Belongs to the P(II) protein family.

265072:MFLA RS07900
gene id: 265072:MFLA_RS07900
uniprot id: Q1H127
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

265072:MFLA RS03815
gene id: 265072:MFLA_RS03815
uniprot id: Q1H3C4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

265072:MFLA RS03300
gene id: 265072:MFLA_RS03300
uniprot id: Q1H3M0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell inner membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.

265072:MFLA RS09600
gene id: 265072:MFLA_RS09600
uniprot id: Q1H042
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YciB family.
messages: Cell inner membrane
messages: Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis.

265072:MFLA RS11430
gene id: 265072:MFLA_RS11430
uniprot id: Q1GZ33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

265072:MFLA RS11640
gene id: 265072:MFLA_RS11640
uniprot id: Q1GYZ2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

265072:MFLA RS07600
gene id: 265072:MFLA_RS07600
uniprot id: Q1H188
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Monomer.
messages: Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.

265072:MFLA RS00240
gene id: 265072:MFLA_RS00240
uniprot id: Q1GXB8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

265072:MFLA RS11845
gene id: 265072:MFLA_RS11845
uniprot id: Q1GYV1
names: Function
names: Similarity
messages: Belongs to the TrhO family.
messages: Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.

265072:MFLA RS06790
gene id: 265072:MFLA_RS06790
uniprot id: Q1H1P1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

265072:MFLA RS01425
gene id: 265072:MFLA_RS01425
uniprot id: Q1H4P3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

265072:MFLA RS01785
gene id: 265072:MFLA_RS01785
uniprot id: Q1H4G9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family. TsaC subfamily.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate.

265072:MFLA RS13160
gene id: 265072:MFLA_RS13160
uniprot id: Q1GY40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

265072:MFLA RS10745
gene id: 265072:MFLA_RS10745
uniprot id: Q1GZH1
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

265072:MFLA RS03575
gene id: 265072:MFLA_RS03575
uniprot id: Q1H3H1
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).

265072:MFLA RS13575
gene id: 265072:MFLA_RS13575
uniprot id: Q1GXW0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

265072:MFLA RS11375
gene id: 265072:MFLA_RS11375
uniprot id: Q1GZ45
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A24 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Plays an essential role in type IV pili and type II pseudopili formation by proteolytically removing the leader sequence from substrate proteins and subsequently monomethylating the alpha-amino group of the newly exposed N-terminal phenylalanine.

265072:MFLA RS11535
gene id: 265072:MFLA_RS11535
uniprot id: Q1GZ11
names: Cofactor
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A single active site specifically recognizes both ATP and CTP and is responsible for their addition.
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 1 subfamily.
messages: Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases.
messages: Comprises two domains: an N-terminal domain containing the nucleotidyltransferase activity and a C-terminal HD domain associated with both phosphodiesterase and phosphatase activities.
messages: Magnesium is required for nucleotidyltransferase activity.
messages: Monomer. Can also form homodimers and oligomers.
messages: Nickel for phosphatase activity.

265072:MFLA RS11415
gene id: 265072:MFLA_RS11415
uniprot id: Q1GZ36
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell inner membrane
messages: Cytoplasm
messages: May bind 1 zinc ion per subunit.
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

265072:MFLA RS05965
gene id: 265072:MFLA_RS05965
uniprot id: Q1H251
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell inner membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

265072:MFLA RS03105
gene id: 265072:MFLA_RS03105
uniprot id: Q1H3R1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

265072:MFLA RS01065
gene id: 265072:MFLA_RS01065
uniprot id: Q1H4W1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

265072:MFLA RS10840
gene id: 265072:MFLA_RS10840
uniprot id: Q1GZF2
names: Similarity
messages: Belongs to the GSP E family.

265072:MFLA RS03080
gene id: 265072:MFLA_RS03080
uniprot id: Q1H3R6
names: Similarity
messages: In the N-terminal section; belongs to the CRISPR-associated nuclease Cas3-HD family.
messages: In the central section; belongs to the CRISPR-associated helicase Cas3 family.

265072:MFLA RS00820
gene id: 265072:MFLA_RS00820
uniprot id: Q1H510
names: Subcellular Location Annotation
messages: Membrane

265072:MFLA RS13220
gene id: 265072:MFLA_RS13220
uniprot id: Q1GY28
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

265072:MFLA RS10130
gene id: 265072:MFLA_RS10130
uniprot id: Q1GZT6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum
messages: Belongs to the FliD family.
messages: Homopentamer.
messages: Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
messages: Secreted

265072:MFLA RS03745
gene id: 265072:MFLA_RS03745
uniprot id: Q1H3D8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell inner membrane
messages: Forms a membrane-associated complex with FtsE.
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in cellular division.

265072:MFLA RS00935
gene id: 265072:MFLA_RS00935
uniprot id: Q1H4Y7
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aquaporins contain two tandem repeats each containing three membrane-spanning domains and a pore-forming loop with the signature motif Asn-Pro-Ala (NPA).
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Cell inner membrane
messages: Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

265072:MFLA RS12265
gene id: 265072:MFLA_RS12265
uniprot id: Q1GYM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

265072:MFLA RS00375
gene id: 265072:MFLA_RS00375
uniprot id: Q1GXD2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

265072:MFLA RS01345
gene id: 265072:MFLA_RS01345
uniprot id: Q1H4Q4
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

265072:MFLA RS03725
gene id: 265072:MFLA_RS03725
uniprot id: Q1H3E2
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

265072:MFLA RS04735
gene id: 265072:MFLA_RS04735
uniprot id: Q1H2F1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LapB family.
messages: Cell inner membrane
messages: Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane.

265072:MFLA RS02570
gene id: 265072:MFLA_RS02570
uniprot id: Q1H414
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

265072:MFLA RS06960
gene id: 265072:MFLA_RS06960
uniprot id: Q1H1K8
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

265072:MFLA RS12000
gene id: 265072:MFLA_RS12000
uniprot id: Q1GYS1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

265072:MFLA RS04805
gene id: 265072:MFLA_RS04805
uniprot id: Q1H2D7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

265072:MFLA RS04405
gene id: 265072:MFLA_RS04405
uniprot id: Q1H2L7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RseB family.
messages: Periplasm

265072:MFLA RS01275
gene id: 265072:MFLA_RS01275
uniprot id: Q1H4R8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

265072:MFLA RS12200
gene id: 265072:MFLA_RS12200
uniprot id: Q1GYN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

265072:MFLA RS01560
gene id: 265072:MFLA_RS01560
uniprot id: Q1H4L6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

265072:MFLA RS04580
gene id: 265072:MFLA_RS04580
uniprot id: Q1H2I2
names: Similarity
messages: Belongs to the XFP family.

265072:MFLA RS12325
gene id: 265072:MFLA_RS12325
uniprot id: Q1GYK8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial secretin family.
messages: Cell outer membrane

265072:MFLA RS12700
gene id: 265072:MFLA_RS12700
uniprot id: Q1GYD3
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

265072:MFLA RS12800
gene id: 265072:MFLA_RS12800
uniprot id: Q1GYB3
names: Domain
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
messages: Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.

265072:MFLA RS07665
gene id: 265072:MFLA_RS07665
uniprot id: Q1H174
names: Similarity
messages: Belongs to the transposase 7 family.

265072:MFLA RS08280
gene id: 265072:MFLA_RS08280
uniprot id: Q1H0V3
names: Similarity
messages: Belongs to the YfgM family.

265072:MFLA RS09030
gene id: 265072:MFLA_RS09030
uniprot id: Q1H0F5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
messages: Cytoplasm
messages: Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
messages: Homodimer. UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

265072:MFLA RS07605
gene id: 265072:MFLA_RS07605
uniprot id: Q1H187
names: Similarity
messages: Belongs to the transglycosylase Slt family.