263358:VAB18032 RS26455
gene id: 263358:VAB18032_RS26455
uniprot id: F4FDE9
names: Similarity
messages: Belongs to the group II decarboxylase family.

263358:VAB18032 RS11065
gene id: 263358:VAB18032_RS11065
uniprot id: F4F5N2
names: Similarity
messages: Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family.

263358:VAB18032 RS05250
gene id: 263358:VAB18032_RS05250
uniprot id: F4F6D2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division.

263358:VAB18032 RS15865
gene id: 263358:VAB18032_RS15865
uniprot id: F4F1J7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

263358:VAB18032 RS13485
gene id: 263358:VAB18032_RS13485
uniprot id: F4FBU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

263358:VAB18032 RS22820
gene id: 263358:VAB18032_RS22820
uniprot id: F4F3Z5
names: Similarity
messages: Belongs to the SurE nucleotidase family.

263358:VAB18032 RS09040
gene id: 263358:VAB18032_RS09040
uniprot id: F4FG85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VKOR family.
messages: Membrane

263358:VAB18032 RS15115
gene id: 263358:VAB18032_RS15115
uniprot id: F4FGD8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

263358:VAB18032 RS16205
gene id: 263358:VAB18032_RS16205
uniprot id: F4F2M9
names: Subcellular Location Annotation
messages: Membrane

263358:VAB18032 RS26830
gene id: 263358:VAB18032_RS26830
uniprot id: F4FEJ5
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

263358:VAB18032 RS21685
gene id: 263358:VAB18032_RS21685
uniprot id: F4FHP5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

263358:VAB18032 RS14455
gene id: 263358:VAB18032_RS14455
uniprot id: F4FE71
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

263358:VAB18032 RS13580
gene id: 263358:VAB18032_RS13580
uniprot id: F4FBW6
names: Subcellular Location Annotation
messages: Membrane

263358:VAB18032 RS18835
gene id: 263358:VAB18032_RS18835
uniprot id: F4F9Q2
names: Similarity
messages: Belongs to the DEAD box helicase family.

263358:VAB18032 RS06685
gene id: 263358:VAB18032_RS06685
uniprot id: F4FAD7
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

263358:VAB18032 RS26410
gene id: 263358:VAB18032_RS26410
uniprot id: F4FDE0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

263358:VAB18032 RS07220
gene id: 263358:VAB18032_RS07220
uniprot id: F4FBK3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

263358:VAB18032 RS22525
gene id: 263358:VAB18032_RS22525
uniprot id: F4F2X3
names: Similarity
messages: Belongs to the Nudix hydrolase family.

263358:VAB18032 RS28960
gene id: 263358:VAB18032_RS28960
uniprot id: F4F383
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

263358:VAB18032 RS11740
gene id: 263358:VAB18032_RS11740
uniprot id: F4F7E9
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

263358:VAB18032 RS11595
gene id: 263358:VAB18032_RS11595
uniprot id: F4F6N0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

263358:VAB18032 RS10130
gene id: 263358:VAB18032_RS10130
uniprot id: F4F2H8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

263358:VAB18032 RS03690
gene id: 263358:VAB18032_RS03690
uniprot id: F4F277
names: Similarity
messages: Belongs to the Fur family.

263358:VAB18032 RS11825
gene id: 263358:VAB18032_RS11825
uniprot id: F4F7G6
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

263358:VAB18032 RS22735
gene id: 263358:VAB18032_RS22735
uniprot id: F4F3X8
names: Subcellular Location Annotation
messages: Membrane

263358:VAB18032 RS24575
gene id: 263358:VAB18032_RS24575
uniprot id: F4F811
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

263358:VAB18032 RS27495
gene id: 263358:VAB18032_RS27495
uniprot id: F4FGR5
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

263358:VAB18032 RS13055
gene id: 263358:VAB18032_RS13055
uniprot id: F4FAP5
names: Similarity
messages: Belongs to the acetaldehyde dehydrogenase family.

263358:VAB18032 RS18865
gene id: 263358:VAB18032_RS18865
uniprot id: F4F9Q8
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

263358:VAB18032 RS29430
gene id: 263358:VAB18032_RS29430
uniprot id: F4F5A9
names: Subcellular Location Annotation
messages: Membrane

263358:VAB18032 RS11715
gene id: 263358:VAB18032_RS11715
uniprot id: F4F6Q5
names: Similarity
messages: Belongs to the cytochrome P450 family.

263358:VAB18032 RS10400
gene id: 263358:VAB18032_RS10400
uniprot id: F4F3K1
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

263358:VAB18032 RS28750
gene id: 263358:VAB18032_RS28750
uniprot id: F4F343
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 10 (cellulase F) family.
messages: Secreted

263358:VAB18032 RS23295
gene id: 263358:VAB18032_RS23295
uniprot id: F4F550
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

263358:VAB18032 RS08895
gene id: 263358:VAB18032_RS08895
uniprot id: F4FG56
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UreD family.
messages: Cytoplasm
messages: Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
messages: UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

263358:VAB18032 RS13000
gene id: 263358:VAB18032_RS13000
uniprot id: F4FAN4
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

263358:VAB18032 RS07650
gene id: 263358:VAB18032_RS07650
uniprot id: F4FCQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

263358:VAB18032 RS08380
gene id: 263358:VAB18032_RS08380
uniprot id: F4FEY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

263358:VAB18032 RS27800
gene id: 263358:VAB18032_RS27800
uniprot id: F4FHU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

263358:VAB18032 RS02550
gene id: 263358:VAB18032_RS02550
uniprot id: F4FFV6
names: Similarity
messages: Belongs to the cytochrome P450 family.

263358:VAB18032 RS21150
gene id: 263358:VAB18032_RS21150
uniprot id: F4FGH0
names: Function
names: Similarity
messages: Belongs to the RapZ-like family.
messages: Displays ATPase and GTPase activities.

263358:VAB18032 RS07045
gene id: 263358:VAB18032_RS07045
uniprot id: F4FAK3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

263358:VAB18032 RS01540
gene id: 263358:VAB18032_RS01540
uniprot id: F4FCK5
names: Function
names: Similarity
messages: Belongs to the MqnA/MqnD family. MqnA subfamily.
messages: Catalyzes the dehydration of chorismate into 3-[(1-carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2).

263358:VAB18032 RS24625
gene id: 263358:VAB18032_RS24625
uniprot id: F4F821
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

263358:VAB18032 RS00155
gene id: 263358:VAB18032_RS00155
uniprot id: F4F927
names: Similarity
messages: Belongs to the SufE family.

263358:VAB18032 RS20565
gene id: 263358:VAB18032_RS20565
uniprot id: F4FEB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

263358:VAB18032 RS07365
gene id: 263358:VAB18032_RS07365
uniprot id: F4FBN2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

263358:VAB18032 RS17860
gene id: 263358:VAB18032_RS17860
uniprot id: F4F6V3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein SsuA/TauA family.
messages: Periplasm

263358:VAB18032 RS21435
gene id: 263358:VAB18032_RS21435
uniprot id: F4FGM8
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

263358:VAB18032 RS26665
gene id: 263358:VAB18032_RS26665
uniprot id: F4FEG1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

263358:VAB18032 RS21820
gene id: 263358:VAB18032_RS21820
uniprot id: F4FHS2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

263358:VAB18032 RS11965
gene id: 263358:VAB18032_RS11965
uniprot id: F4F7J4
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

263358:VAB18032 RS18515
gene id: 263358:VAB18032_RS18515
uniprot id: F4F8M0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 13 family.
messages: Cytoplasm

263358:VAB18032 RS25315
gene id: 263358:VAB18032_RS25315
uniprot id: F4FA23
names: Similarity
messages: Belongs to the peptidase S8 family.

263358:VAB18032 RS17120
gene id: 263358:VAB18032_RS17120
uniprot id: F4F4Z0
names: Subcellular Location Annotation
messages: Membrane

263358:VAB18032 RS19230
gene id: 263358:VAB18032_RS19230
uniprot id: F4FAU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polysaccharide lyase 1 family.
messages: Secreted

263358:VAB18032 RS29530
gene id: 263358:VAB18032_RS29530
uniprot id: F4F5D0
names: Similarity
messages: Belongs to the 6-phosphogluconate dehydrogenase family.

263358:VAB18032 RS13015
gene id: 263358:VAB18032_RS13015
uniprot id: F4FAN7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

263358:VAB18032 RS28035
gene id: 263358:VAB18032_RS28035
uniprot id: F4FHZ1
names: Similarity
messages: Belongs to the adenylyl cyclase class-3 family.

263358:VAB18032 RS12345
gene id: 263358:VAB18032_RS12345
uniprot id: F4F8G8
names: Similarity
messages: Belongs to the cytochrome P450 family.

263358:VAB18032 RS20625
gene id: 263358:VAB18032_RS20625
uniprot id: F4FED0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurD2 subfamily.
messages: Cell wall formation. Catalyzes the addition of L-glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine.
messages: Cytoplasm

263358:VAB18032 RS21595
gene id: 263358:VAB18032_RS21595
uniprot id: F4FHM8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

263358:VAB18032 RS21195
gene id: 263358:VAB18032_RS21195
uniprot id: F4FGI0
names: Similarity
messages: Belongs to the peptidase S45 family.

263358:VAB18032 RS23090
gene id: 263358:VAB18032_RS23090
uniprot id: F4F445
names: Similarity
messages: Belongs to the myo-inositol 1-phosphate synthase family.

263358:VAB18032 RS15655
gene id: 263358:VAB18032_RS15655
uniprot id: F4F1F6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase-binding protein RbpA family.
messages: Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters.
messages: Forms a complex with the RNAP catalytic core and with free principal sigma factors.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

263358:VAB18032 RS24590
gene id: 263358:VAB18032_RS24590
uniprot id: F4F814
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

263358:VAB18032 RS19970
gene id: 263358:VAB18032_RS19970
uniprot id: F4FC63
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

263358:VAB18032 RS18345
gene id: 263358:VAB18032_RS18345
uniprot id: F4F7U0
names: Similarity
messages: Belongs to the cysteine dioxygenase family.

263358:VAB18032 RS25700
gene id: 263358:VAB18032_RS25700
uniprot id: F4FB66
names: Subcellular Location Annotation
messages: Membrane

263358:VAB18032 RS01165
gene id: 263358:VAB18032_RS01165
uniprot id: F4FBG0
names: Similarity
messages: Belongs to the Nudix hydrolase family.

263358:VAB18032 RS29235
gene id: 263358:VAB18032_RS29235
uniprot id: F4F4A5
names: Similarity
messages: Belongs to the fructosamine kinase family.

263358:VAB18032 RS21790
gene id: 263358:VAB18032_RS21790
uniprot id: F4FHR6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

263358:VAB18032 RS28985
gene id: 263358:VAB18032_RS28985
uniprot id: F4F454
names: Similarity
messages: Belongs to the Nudix hydrolase family.

263358:VAB18032 RS16830
gene id: 263358:VAB18032_RS16830
uniprot id: F4F3W7
names: Similarity
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.

263358:VAB18032 RS25895
gene id: 263358:VAB18032_RS25895
uniprot id: F4FC71
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

263358:VAB18032 RS22485
gene id: 263358:VAB18032_RS22485
uniprot id: F4F2W5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0719 family.
messages: Membrane

263358:VAB18032 RS01385
gene id: 263358:VAB18032_RS01385
uniprot id: F4FCH4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

263358:VAB18032 RS07065
gene id: 263358:VAB18032_RS07065
uniprot id: F4FAK7
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

263358:VAB18032 RS27900
gene id: 263358:VAB18032_RS27900
uniprot id: F4FHW3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

263358:VAB18032 RS19975
gene id: 263358:VAB18032_RS19975
uniprot id: F4FC64
names: Similarity
messages: Belongs to the glycosyltransferase 28 family.

263358:VAB18032 RS23615
gene id: 263358:VAB18032_RS23615
uniprot id: F4F641
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

263358:VAB18032 RS02740
gene id: 263358:VAB18032_RS02740
uniprot id: F4FFZ4
names: Subcellular Location Annotation
messages: Membrane

263358:VAB18032 RS23210
gene id: 263358:VAB18032_RS23210
uniprot id: F4F533
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

263358:VAB18032 RS25410
gene id: 263358:VAB18032_RS25410
uniprot id: F4FA42
names: Similarity
messages: Belongs to the peptidase U62 family.

263358:VAB18032 RS24695
gene id: 263358:VAB18032_RS24695
uniprot id: F4F8T0
names: Function
names: Similarity
messages: Belongs to the threonine synthase family.
messages: Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.

263358:VAB18032 RS28335
gene id: 263358:VAB18032_RS28335
uniprot id: F4F1Z7
names: Cofactor
messages: Binds 1 FAD per subunit.

263358:VAB18032 RS26525
gene id: 263358:VAB18032_RS26525
uniprot id: F4FDG3
names: Similarity
messages: Belongs to the DEAD box helicase family.

263358:VAB18032 RS28540
gene id: 263358:VAB18032_RS28540
uniprot id: F4F237
names: Similarity
messages: Belongs to the WXG100 family.

263358:VAB18032 RS09400
gene id: 263358:VAB18032_RS09400
uniprot id: F4FHC3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
messages: Homotetramer.
messages: Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

263358:VAB18032 RS19495
gene id: 263358:VAB18032_RS19495
uniprot id: F4FB01
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

263358:VAB18032 RS24290
gene id: 263358:VAB18032_RS24290
uniprot id: F4F764
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Catalyzes the phosphorylation of D-xylulose to D-xylulose 5-phosphate.

263358:VAB18032 RS27050
gene id: 263358:VAB18032_RS27050
uniprot id: F4FFK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

263358:VAB18032 RS17755
gene id: 263358:VAB18032_RS17755
uniprot id: F4F6T3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UreF family.
messages: Cytoplasm
messages: Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
messages: UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

263358:VAB18032 RS00640
gene id: 263358:VAB18032_RS00640
uniprot id: F4FA92
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

263358:VAB18032 RS14065
gene id: 263358:VAB18032_RS14065
uniprot id: F4FD31
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

263358:VAB18032 RS11500
gene id: 263358:VAB18032_RS11500
uniprot id: F4F6L0
names: Similarity
messages: Belongs to the histone deacetylase family.

263358:VAB18032 RS10660
gene id: 263358:VAB18032_RS10660
uniprot id: F4F4M0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

263358:VAB18032 RS26250
gene id: 263358:VAB18032_RS26250
uniprot id: F4FCE2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

263358:VAB18032 RS08865
gene id: 263358:VAB18032_RS08865
uniprot id: F4FG50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urease gamma subunit family.
messages: Cytoplasm

263358:VAB18032 RS06790
gene id: 263358:VAB18032_RS06790
uniprot id: F4FAF5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

263358:VAB18032 RS24250
gene id: 263358:VAB18032_RS24250
uniprot id: F4F756
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TspO/BZRP family.
messages: Membrane

263358:VAB18032 RS13280
gene id: 263358:VAB18032_RS13280
uniprot id: F4FBQ6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

263358:VAB18032 RS26210
gene id: 263358:VAB18032_RS26210
uniprot id: F4FCD4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

263358:VAB18032 RS01725
gene id: 263358:VAB18032_RS01725
uniprot id: F4FDK6
names: Similarity
messages: Belongs to the WXG100 family.

263358:VAB18032 RS00375
gene id: 263358:VAB18032_RS00375
uniprot id: F4F970
names: Similarity
messages: Belongs to the UPF0749 family.

263358:VAB18032 RS25520
gene id: 263358:VAB18032_RS25520
uniprot id: F4FB30
names: Caution
names: Function
names: Similarity
messages: Belongs to the APS kinase family.
messages: Catalyzes the synthesis of activated sulfate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

263358:VAB18032 RS07550
gene id: 263358:VAB18032_RS07550
uniprot id: F4FCN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

263358:VAB18032 RS23865
gene id: 263358:VAB18032_RS23865
uniprot id: F4F691
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

263358:VAB18032 RS07595
gene id: 263358:VAB18032_RS07595
uniprot id: F4FCP7
names: Similarity
messages: Belongs to the FPG family.

263358:VAB18032 RS15345
gene id: 263358:VAB18032_RS15345
uniprot id: F4FHF0
names: Subcellular Location Annotation
messages: Membrane

263358:VAB18032 RS05940
gene id: 263358:VAB18032_RS05940
uniprot id: F4F857
names: Subcellular Location Annotation
messages: Membrane

263358:VAB18032 RS21205
gene id: 263358:VAB18032_RS21205
uniprot id: F4FGI2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

263358:VAB18032 RS32110
gene id: 263358:VAB18032_RS32110
uniprot id: F4FBV4
names: Similarity
messages: Belongs to the YciI family.

263358:VAB18032 RS10800
gene id: 263358:VAB18032_RS10800
uniprot id: F4F4P5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

263358:VAB18032 RS25580
gene id: 263358:VAB18032_RS25580
uniprot id: F4FB42
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

263358:VAB18032 RS00675
gene id: 263358:VAB18032_RS00675
uniprot id: F4FA99
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.

263358:VAB18032 RS05355
gene id: 263358:VAB18032_RS05355
uniprot id: F4F6F2
names: Similarity
messages: Belongs to the AHA1 family.

263358:VAB18032 RS11560
gene id: 263358:VAB18032_RS11560
uniprot id: F4F6M2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

263358:VAB18032 RS10795
gene id: 263358:VAB18032_RS10795
uniprot id: F4F4P4
names: Similarity
messages: Belongs to the TlyA family.

263358:VAB18032 RS07465
gene id: 263358:VAB18032_RS07465
uniprot id: F4FBQ3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

263358:VAB18032 RS10425
gene id: 263358:VAB18032_RS10425
uniprot id: F4F3K6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
messages: Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.
messages: Cytoplasm
messages: Homodimer.

263358:VAB18032 RS17575
gene id: 263358:VAB18032_RS17575
uniprot id: F4F613
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

263358:VAB18032 RS13890
gene id: 263358:VAB18032_RS13890
uniprot id: F4FCZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

263358:VAB18032 RS06655
gene id: 263358:VAB18032_RS06655
uniprot id: F4F9G4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

263358:VAB18032 RS16135
gene id: 263358:VAB18032_RS16135
uniprot id: F4F2L5
names: Cofactor
messages: Binds 4 [4Fe-4S] clusters per subunit.

263358:VAB18032 RS20660
gene id: 263358:VAB18032_RS20660
uniprot id: F4FED8
names: Function
names: Similarity
messages: Belongs to the KptA/TPT1 family.
messages: Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP-ribose 1''-2''-cyclic phosphate (APPR>P). May function as an ADP-ribosylase.

263358:VAB18032 RS02650
gene id: 263358:VAB18032_RS02650
uniprot id: F4FFX6
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

263358:VAB18032 RS08870
gene id: 263358:VAB18032_RS08870
uniprot id: F4FG51
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease beta subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

263358:VAB18032 RS02680
gene id: 263358:VAB18032_RS02680
uniprot id: F4FFY2
names: Similarity
messages: Belongs to the GST superfamily. NadH family.

263358:VAB18032 RS07770
gene id: 263358:VAB18032_RS07770
uniprot id: F4FCT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

263358:VAB18032 RS10375
gene id: 263358:VAB18032_RS10375
uniprot id: F4F3J6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

263358:VAB18032 RS18870
gene id: 263358:VAB18032_RS18870
uniprot id: F4F9Q9
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

263358:VAB18032 RS07930
gene id: 263358:VAB18032_RS07930
uniprot id: F4FDS8
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

263358:VAB18032 RS13115
gene id: 263358:VAB18032_RS13115
uniprot id: F4FAQ7
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

263358:VAB18032 RS21375
gene id: 263358:VAB18032_RS21375
uniprot id: F4FGL7
names: Similarity
messages: Belongs to the leucine-binding protein family.

263358:VAB18032 RS14715
gene id: 263358:VAB18032_RS14715
uniprot id: F4FF89
names: Subcellular Location Annotation
messages: Membrane

263358:VAB18032 RS20940
gene id: 263358:VAB18032_RS20940
uniprot id: F4FFG1
names: Similarity
messages: Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.

263358:VAB18032 RS07960
gene id: 263358:VAB18032_RS07960
uniprot id: F4FDT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

263358:VAB18032 RS14075
gene id: 263358:VAB18032_RS14075
uniprot id: F4FDZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

263358:VAB18032 RS10275
gene id: 263358:VAB18032_RS10275
uniprot id: F4F3H3
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

263358:VAB18032 RS04430
gene id: 263358:VAB18032_RS04430
uniprot id: F4F4F5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

263358:VAB18032 RS18735
gene id: 263358:VAB18032_RS18735
uniprot id: F4F8R5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GDT1 family.
messages: Membrane

263358:VAB18032 RS21275
gene id: 263358:VAB18032_RS21275
uniprot id: F4FGJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

263358:VAB18032 RS21720
gene id: 263358:VAB18032_RS21720
uniprot id: F4FHQ2
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

263358:VAB18032 RS19020
gene id: 263358:VAB18032_RS19020
uniprot id: F4F9T9
names: Subcellular Location Annotation
messages: Membrane

263358:VAB18032 RS22575
gene id: 263358:VAB18032_RS22575
uniprot id: F4F2Y3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

263358:VAB18032 RS27310
gene id: 263358:VAB18032_RS27310
uniprot id: F4FFR2
names: Subcellular Location Annotation
messages: Cytoplasm

263358:VAB18032 RS01830
gene id: 263358:VAB18032_RS01830
uniprot id: F4FDM8
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

263358:VAB18032 RS20465
gene id: 263358:VAB18032_RS20465
uniprot id: F4FE97
names: Similarity
messages: Belongs to the HsdR family.

263358:VAB18032 RS09045
gene id: 263358:VAB18032_RS09045
uniprot id: F4FG86
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

263358:VAB18032 RS17485
gene id: 263358:VAB18032_RS17485
uniprot id: F4F5Z4
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

263358:VAB18032 RS20125
gene id: 263358:VAB18032_RS20125
uniprot id: F4FD64
names: Subcellular Location Annotation
messages: Membrane

263358:VAB18032 RS07885
gene id: 263358:VAB18032_RS07885
uniprot id: F4FDR9
names: Similarity
messages: Belongs to the YciI family.

263358:VAB18032 RS24825
gene id: 263358:VAB18032_RS24825
uniprot id: F4F8V5
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family.

263358:VAB18032 RS20505
gene id: 263358:VAB18032_RS20505
uniprot id: F4FEA6
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

263358:VAB18032 RS22495
gene id: 263358:VAB18032_RS22495
uniprot id: F4F2W7
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

263358:VAB18032 RS18840
gene id: 263358:VAB18032_RS18840
uniprot id: F4F9Q3
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

263358:VAB18032 RS27475
gene id: 263358:VAB18032_RS27475
uniprot id: F4FGR2
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

263358:VAB18032 RS01620
gene id: 263358:VAB18032_RS01620
uniprot id: F4FCM1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

263358:VAB18032 RS00740
gene id: 263358:VAB18032_RS00740
uniprot id: F4FAB2
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

263358:VAB18032 RS07515
gene id: 263358:VAB18032_RS07515
uniprot id: F4FCN1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

263358:VAB18032 RS21040
gene id: 263358:VAB18032_RS21040
uniprot id: F4FFI1
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

263358:VAB18032 RS09905
gene id: 263358:VAB18032_RS09905
uniprot id: F4F2D3
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.

263358:VAB18032 RS26090
gene id: 263358:VAB18032_RS26090
uniprot id: F4FCB0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

263358:VAB18032 RS01970
gene id: 263358:VAB18032_RS01970
uniprot id: F4FDQ7
names: Subcellular Location Annotation
messages: Membrane

263358:VAB18032 RS03835
gene id: 263358:VAB18032_RS03835
uniprot id: F4F2A6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

263358:VAB18032 RS04570
gene id: 263358:VAB18032_RS04570
uniprot id: F4F4I5
names: Similarity
messages: Belongs to the creatininase superfamily.

263358:VAB18032 RS16050
gene id: 263358:VAB18032_RS16050
uniprot id: F4F1N4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

263358:VAB18032 RS02160
gene id: 263358:VAB18032_RS02160
uniprot id: F4FER4
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

263358:VAB18032 RS02170
gene id: 263358:VAB18032_RS02170
uniprot id: F4FER6
names: Similarity
messages: Belongs to the ABC transporter superfamily.

263358:VAB18032 RS12360
gene id: 263358:VAB18032_RS12360
uniprot id: F4F8H1
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

263358:VAB18032 RS27205
gene id: 263358:VAB18032_RS27205
uniprot id: F4FFN9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetyltransferase family. MshD subfamily.
messages: Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

263358:VAB18032 RS02930
gene id: 263358:VAB18032_RS02930
uniprot id: F4FGZ6
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

263358:VAB18032 RS21365
gene id: 263358:VAB18032_RS21365
uniprot id: F4FGL5
names: Subcellular Location Annotation
messages: Membrane

263358:VAB18032 RS29290
gene id: 263358:VAB18032_RS29290
uniprot id: F4F4B6
names: Subcellular Location Annotation
messages: Membrane

263358:VAB18032 RS15220
gene id: 263358:VAB18032_RS15220
uniprot id: F4FGF9
names: Subcellular Location Annotation
messages: Membrane

263358:VAB18032 RS01995
gene id: 263358:VAB18032_RS01995
uniprot id: F4FDR2
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

263358:VAB18032 RS23410
gene id: 263358:VAB18032_RS23410
uniprot id: F4F573
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

263358:VAB18032 RS08305
gene id: 263358:VAB18032_RS08305
uniprot id: F4FEX2
names: Similarity
messages: Belongs to the stealth family.

263358:VAB18032 RS15040
gene id: 263358:VAB18032_RS15040
uniprot id: F4FGC3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

263358:VAB18032 RS10555
gene id: 263358:VAB18032_RS10555
uniprot id: F4F3N3
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Feedback inhibited by histidine.

263358:VAB18032 RS14735
gene id: 263358:VAB18032_RS14735
uniprot id: F4FF93
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

263358:VAB18032 RS18610
gene id: 263358:VAB18032_RS18610
uniprot id: F4F8P0
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

263358:VAB18032 RS06545
gene id: 263358:VAB18032_RS06545
uniprot id: F4F9E2
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

263358:VAB18032 RS06740
gene id: 263358:VAB18032_RS06740
uniprot id: F4FAE8
names: Similarity
messages: Belongs to the prokaryotic/mitochondrial release factor family.

263358:VAB18032 RS10720
gene id: 263358:VAB18032_RS10720
uniprot id: F4F4N2
names: Subcellular Location Annotation
messages: Membrane

263358:VAB18032 RS17990
gene id: 263358:VAB18032_RS17990
uniprot id: F4F6Y1
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the Pup ligase/Pup deamidase family. Pup-conjugating enzyme subfamily.
messages: Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine.
messages: The reaction mechanism probably proceeds via the activation of Pup by phosphorylation of its C-terminal glutamate, which is then subject to nucleophilic attack by the substrate lysine, resulting in an isopeptide bond and the release of phosphate as a good leaving group.

263358:VAB18032 RS07105
gene id: 263358:VAB18032_RS07105
uniprot id: F4FBI0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

263358:VAB18032 RS28310
gene id: 263358:VAB18032_RS28310
uniprot id: F4F1Z2
names: Subcellular Location Annotation
messages: Membrane

263358:VAB18032 RS06700
gene id: 263358:VAB18032_RS06700
uniprot id: F4FAE0
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

263358:VAB18032 RS22085
gene id: 263358:VAB18032_RS22085
uniprot id: F4F1R9
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

263358:VAB18032 RS15450
gene id: 263358:VAB18032_RS15450
uniprot id: F4FHH2
names: Function
messages: Acyltransferase required for the direct transfer of medium- to long-chain fatty acyl moieties from a carrier protein (MbtL) on to the epsilon-amino group of lysine residue in the mycobactin core.

263358:VAB18032 RS19205
gene id: 263358:VAB18032_RS19205
uniprot id: F4FAU0
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Uronate isomerase family.

263358:VAB18032 RS07705
gene id: 263358:VAB18032_RS07705
uniprot id: F4FCR9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

263358:VAB18032 RS01635
gene id: 263358:VAB18032_RS01635
uniprot id: F4FDI8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the complex I 75 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

263358:VAB18032 RS22310
gene id: 263358:VAB18032_RS22310
uniprot id: F4F2T0
names: Similarity
messages: Belongs to the shaker potassium channel beta subunit family.

263358:VAB18032 RS20375
gene id: 263358:VAB18032_RS20375
uniprot id: F4FE78
names: Similarity
messages: Belongs to the peptidase S15 family.

263358:VAB18032 RS26155
gene id: 263358:VAB18032_RS26155
uniprot id: F4FCC3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

263358:VAB18032 RS00395
gene id: 263358:VAB18032_RS00395
uniprot id: F4F974
names: Similarity
messages: Belongs to the peptidase C40 family.

263358:VAB18032 RS23500
gene id: 263358:VAB18032_RS23500
uniprot id: F4F591
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

263358:VAB18032 RS09485
gene id: 263358:VAB18032_RS09485
uniprot id: F4F182
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

263358:VAB18032 RS24430
gene id: 263358:VAB18032_RS24430
uniprot id: F4F7Y1
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

263358:VAB18032 RS04730
gene id: 263358:VAB18032_RS04730
uniprot id: F4F5E1
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

263358:VAB18032 RS09955
gene id: 263358:VAB18032_RS09955
uniprot id: F4F2E4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Catalyzes the conjugation of the 1'-hydroxyl group of D-myo-inositol-3-phosphate (also named L-myo-inositol-1-phosphate) with a lipid tail of cytidine diphosphate diacylglycerol (CDP-DAG), forming phosphatidylinositol phosphate (PIP) and CMP. PIP is a precursor of phosphatidylinositol (PI) which is an essential lipid required for cell wall formation.
messages: Cell membrane
messages: Contains a di-nuclear catalytic Mg(2+) center.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

263358:VAB18032 RS08540
gene id: 263358:VAB18032_RS08540
uniprot id: F4FF15
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

263358:VAB18032 RS01430
gene id: 263358:VAB18032_RS01430
uniprot id: F4FCI3
names: Similarity
messages: Belongs to the terpene synthase family.

263358:VAB18032 RS21290
gene id: 263358:VAB18032_RS21290
uniprot id: F4FGJ9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

263358:VAB18032 RS10475
gene id: 263358:VAB18032_RS10475
uniprot id: F4F3L6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

263358:VAB18032 RS18070
gene id: 263358:VAB18032_RS18070
uniprot id: F4F7N4
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

263358:VAB18032 RS04865
gene id: 263358:VAB18032_RS04865
uniprot id: F4F5G8
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

263358:VAB18032 RS26955
gene id: 263358:VAB18032_RS26955
uniprot id: F4FEM1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

263358:VAB18032 RS15885
gene id: 263358:VAB18032_RS15885
uniprot id: F4F1K1
names: Subcellular Location Annotation
messages: Membrane

263358:VAB18032 RS02085
gene id: 263358:VAB18032_RS02085
uniprot id: F4FEP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Membrane

263358:VAB18032 RS09360
gene id: 263358:VAB18032_RS09360
uniprot id: F4FHB5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgE subfamily.
messages: Homodimer.
messages: Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1->4)-glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB.

263358:VAB18032 RS04765
gene id: 263358:VAB18032_RS04765
uniprot id: F4F5E8
names: Similarity
messages: Belongs to the peptidase M42 family.

263358:VAB18032 RS22785
gene id: 263358:VAB18032_RS22785
uniprot id: F4F3Y8
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

263358:VAB18032 RS10630
gene id: 263358:VAB18032_RS10630
uniprot id: F4F4L4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

263358:VAB18032 RS11645
gene id: 263358:VAB18032_RS11645
uniprot id: F4F6P0
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

263358:VAB18032 RS22925
gene id: 263358:VAB18032_RS22925
uniprot id: F4F417
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

263358:VAB18032 RS02260
gene id: 263358:VAB18032_RS02260
uniprot id: F4FET4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

263358:VAB18032 RS03980
gene id: 263358:VAB18032_RS03980
uniprot id: F4F3A0
names: Similarity
messages: Belongs to the PAPS reductase family. CysD subfamily.

263358:VAB18032 RS05195
gene id: 263358:VAB18032_RS05195
uniprot id: F4F6C1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

263358:VAB18032 RS26400
gene id: 263358:VAB18032_RS26400
uniprot id: F4FDD8
names: Subcellular Location Annotation
messages: Membrane

263358:VAB18032 RS28145
gene id: 263358:VAB18032_RS28145
uniprot id: F4FI14
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

263358:VAB18032 RS09995
gene id: 263358:VAB18032_RS09995
uniprot id: F4F2F2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

263358:VAB18032 RS07525
gene id: 263358:VAB18032_RS07525
uniprot id: F4FCN3
names: Similarity
messages: Belongs to the peptidase S1 family.

263358:VAB18032 RS27750
gene id: 263358:VAB18032_RS27750
uniprot id: F4FGW6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate, the first step in the de novo biosynthesis of NAD(+).
messages: Cytoplasm

263358:VAB18032 RS30090
gene id: 263358:VAB18032_RS30090
uniprot id: F4FBX5
names: Similarity
messages: Belongs to the glycosyl hydrolase 10 (cellulase F) family.

263358:VAB18032 RS00830
gene id: 263358:VAB18032_RS00830
uniprot id: F4FAD0
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

263358:VAB18032 RS12745
gene id: 263358:VAB18032_RS12745
uniprot id: F4F9L6
names: Similarity
messages: Belongs to the peptidase C56 family.

263358:VAB18032 RS25300
gene id: 263358:VAB18032_RS25300
uniprot id: F4FA19
names: Similarity
messages: Belongs to the LOG family.

263358:VAB18032 RS27590
gene id: 263358:VAB18032_RS27590
uniprot id: F4FGT4
names: Cofactor
names: Similarity
messages: Belongs to the 4HPPD family.
messages: Binds 1 Fe cation per subunit.

263358:VAB18032 RS04025
gene id: 263358:VAB18032_RS04025
uniprot id: F4F3A9
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

263358:VAB18032 RS05970
gene id: 263358:VAB18032_RS05970
uniprot id: F4F863
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: May be specifically involved in the processing, transport, and/or maturation of the MADH beta-subunit.
messages: Membrane

263358:VAB18032 RS24200
gene id: 263358:VAB18032_RS24200
uniprot id: F4F745
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

263358:VAB18032 RS06560
gene id: 263358:VAB18032_RS06560
uniprot id: F4F9E5
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

263358:VAB18032 RS25030
gene id: 263358:VAB18032_RS25030
uniprot id: F4F8Z7
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

263358:VAB18032 RS14575
gene id: 263358:VAB18032_RS14575
uniprot id: F4FF59
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

263358:VAB18032 RS08750
gene id: 263358:VAB18032_RS08750
uniprot id: F4FG25
names: Subunit
messages: Homodimer.

263358:VAB18032 RS17960
gene id: 263358:VAB18032_RS17960
uniprot id: F4F6X5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

263358:VAB18032 RS12020
gene id: 263358:VAB18032_RS12020
uniprot id: F4F7K5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

263358:VAB18032 RS14620
gene id: 263358:VAB18032_RS14620
uniprot id: F4FF70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

263358:VAB18032 RS25930
gene id: 263358:VAB18032_RS25930
uniprot id: F4FC78
names: Function
messages: Catalyzes the reduction of sulfite to sulfide, a step in the biosynthesis of sulfur-containing amino acids and cofactors.

263358:VAB18032 RS01410
gene id: 263358:VAB18032_RS01410
uniprot id: F4FCH9
names: Subcellular Location Annotation
messages: Membrane

263358:VAB18032 RS07300
gene id: 263358:VAB18032_RS07300
uniprot id: F4FBL9
names: Similarity
messages: Belongs to the F420H(2)-dependent quinone reductase family.

263358:VAB18032 RS22335
gene id: 263358:VAB18032_RS22335
uniprot id: F4F2T5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Membrane

263358:VAB18032 RS08600
gene id: 263358:VAB18032_RS08600
uniprot id: F4FF27
names: Similarity
messages: Belongs to the XFP family.

263358:VAB18032 RS04565
gene id: 263358:VAB18032_RS04565
uniprot id: F4F4I4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

263358:VAB18032 RS10405
gene id: 263358:VAB18032_RS10405
uniprot id: F4F3K2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

263358:VAB18032 RS18370
gene id: 263358:VAB18032_RS18370
uniprot id: F4F7U5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

263358:VAB18032 RS28375
gene id: 263358:VAB18032_RS28375
uniprot id: F4F205
names: Similarity
messages: Belongs to the PNP/UDP phosphorylase family.

263358:VAB18032 RS16025
gene id: 263358:VAB18032_RS16025
uniprot id: F4F1M9
names: Cofactor
names: Similarity
messages: Belongs to the truncated hemoglobin family. Group I subfamily.
messages: Binds 1 heme group per subunit.

263358:VAB18032 RS16915
gene id: 263358:VAB18032_RS16915
uniprot id: F4F4U8
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

263358:VAB18032 RS12725
gene id: 263358:VAB18032_RS12725
uniprot id: F4F9L2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

263358:VAB18032 RS00615
gene id: 263358:VAB18032_RS00615
uniprot id: F4FA87
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

263358:VAB18032 RS04950
gene id: 263358:VAB18032_RS04950
uniprot id: F4F5I5
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

263358:VAB18032 RS02415
gene id: 263358:VAB18032_RS02415
uniprot id: F4FFS9
names: Similarity
messages: Belongs to the YciI family.

263358:VAB18032 RS21130
gene id: 263358:VAB18032_RS21130
uniprot id: F4FFJ9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

263358:VAB18032 RS20325
gene id: 263358:VAB18032_RS20325
uniprot id: F4FDA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

263358:VAB18032 RS09405
gene id: 263358:VAB18032_RS09405
uniprot id: F4FHC4
names: Similarity
messages: Belongs to the phosphohexose mutase family.

263358:VAB18032 RS02595
gene id: 263358:VAB18032_RS02595
uniprot id: F4FFW5
names: Similarity
messages: Belongs to the cytochrome P450 family.

263358:VAB18032 RS16200
gene id: 263358:VAB18032_RS16200
uniprot id: F4F2M8
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

263358:VAB18032 RS24065
gene id: 263358:VAB18032_RS24065
uniprot id: F4F718
names: Similarity
messages: Belongs to the peptidase S33 family.

263358:VAB18032 RS00380
gene id: 263358:VAB18032_RS00380
uniprot id: F4F971
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrgA family.
messages: Cell membrane
messages: Involved in cell division.

263358:VAB18032 RS25285
gene id: 263358:VAB18032_RS25285
uniprot id: F4FA16
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

263358:VAB18032 RS19565
gene id: 263358:VAB18032_RS19565
uniprot id: F4FB15
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

263358:VAB18032 RS20235
gene id: 263358:VAB18032_RS20235
uniprot id: F4FD86
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

263358:VAB18032 RS05850
gene id: 263358:VAB18032_RS05850
uniprot id: F4F7E3
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20 family.
messages: Binds 2 Zn(2+) ions per subunit.

263358:VAB18032 RS19945
gene id: 263358:VAB18032_RS19945
uniprot id: F4FC57
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

263358:VAB18032 RS08440
gene id: 263358:VAB18032_RS08440
uniprot id: F4FF00
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

263358:VAB18032 RS06810
gene id: 263358:VAB18032_RS06810
uniprot id: F4FAF9
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

263358:VAB18032 RS19410
gene id: 263358:VAB18032_RS19410
uniprot id: F4FAY3
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

263358:VAB18032 RS27245
gene id: 263358:VAB18032_RS27245
uniprot id: F4FFP7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Heptamer of 7 subunits arranged in a ring.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

263358:VAB18032 RS11005
gene id: 263358:VAB18032_RS11005
uniprot id: F4F5L6
names: Similarity
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Homohexamer. The oligomerization is ATP-dependent.

263358:VAB18032 RS20320
gene id: 263358:VAB18032_RS20320
uniprot id: F4FDA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

263358:VAB18032 RS25425
gene id: 263358:VAB18032_RS25425
uniprot id: F4FA45
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

263358:VAB18032 RS24495
gene id: 263358:VAB18032_RS24495
uniprot id: F4F7Z5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NucS endonuclease family.
messages: Cleaves both 3' and 5' ssDNA extremities of branched DNA structures.
messages: Cytoplasm

263358:VAB18032 RS01760
gene id: 263358:VAB18032_RS01760
uniprot id: F4FDL3
names: Caution
names: Function
names: PTM
names: Similarity
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

263358:VAB18032 RS27300
gene id: 263358:VAB18032_RS27300
uniprot id: F4FFR0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cell surface
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
messages: capsule
messages: cell wall

263358:VAB18032 RS10655
gene id: 263358:VAB18032_RS10655
uniprot id: F4F4L9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

263358:VAB18032 RS20630
gene id: 263358:VAB18032_RS20630
uniprot id: F4FED1
names: Function
names: Similarity
messages: Belongs to the MurL family.
messages: Cell wall formation. Catalyzes epimerization of the terminal L-glutamate in UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-L-glutamate.

263358:VAB18032 RS17875
gene id: 263358:VAB18032_RS17875
uniprot id: F4F6V6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0324 family.
messages: Membrane

263358:VAB18032 RS10290
gene id: 263358:VAB18032_RS10290
uniprot id: F4F3H8
names: Similarity
messages: Belongs to the glycosyl hydrolase 10 (cellulase F) family.

263358:VAB18032 RS15105
gene id: 263358:VAB18032_RS15105
uniprot id: F4FGD6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

263358:VAB18032 RS19260
gene id: 263358:VAB18032_RS19260
uniprot id: F4FAV2
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

263358:VAB18032 RS23355
gene id: 263358:VAB18032_RS23355
uniprot id: F4F562
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

263358:VAB18032 RS15375
gene id: 263358:VAB18032_RS15375
uniprot id: F4FHF6
names: Similarity
messages: Belongs to the peptidase M7 family.

263358:VAB18032 RS20985
gene id: 263358:VAB18032_RS20985
uniprot id: F4FFH0
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

263358:VAB18032 RS21230
gene id: 263358:VAB18032_RS21230
uniprot id: F4FGI7
names: Subcellular Location Annotation
messages: Cytoplasm

263358:VAB18032 RS19340
gene id: 263358:VAB18032_RS19340
uniprot id: F4FAW9
names: Similarity
messages: Belongs to the glycosyl hydrolase 10 (cellulase F) family.

263358:VAB18032 RS14230
gene id: 263358:VAB18032_RS14230
uniprot id: F4FE27
names: Similarity
messages: Belongs to the AHA1 family.

263358:VAB18032 RS10705
gene id: 263358:VAB18032_RS10705
uniprot id: F4F4M9
names: Subcellular Location Annotation
messages: Cell membrane

263358:VAB18032 RS10415
gene id: 263358:VAB18032_RS10415
uniprot id: F4F3K4
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

263358:VAB18032 RS05020
gene id: 263358:VAB18032_RS05020
uniprot id: F4F5J9
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.

263358:VAB18032 RS22025
gene id: 263358:VAB18032_RS22025
uniprot id: F4F1Q7
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
messages: Cytoplasm
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Non-allosteric.

263358:VAB18032 RS25560
gene id: 263358:VAB18032_RS25560
uniprot id: F4FB38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

263358:VAB18032 RS22890
gene id: 263358:VAB18032_RS22890
uniprot id: F4F410
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

263358:VAB18032 RS14295
gene id: 263358:VAB18032_RS14295
uniprot id: F4FE40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Cell membrane
messages: Membrane

263358:VAB18032 RS27410
gene id: 263358:VAB18032_RS27410
uniprot id: F4FGP9
names: Subcellular Location Annotation
messages: Membrane

263358:VAB18032 RS26570
gene id: 263358:VAB18032_RS26570
uniprot id: F4FDH2
names: Subcellular Location Annotation
messages: Membrane

263358:VAB18032 RS12960
gene id: 263358:VAB18032_RS12960
uniprot id: F4FAM2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

263358:VAB18032 RS10410
gene id: 263358:VAB18032_RS10410
uniprot id: F4F3K3
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

263358:VAB18032 RS05855
gene id: 263358:VAB18032_RS05855
uniprot id: F4F7E4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urocanase family.
messages: Binds 1 NAD(+) per subunit.
messages: Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
messages: Cytoplasm

263358:VAB18032 RS02750
gene id: 263358:VAB18032_RS02750
uniprot id: F4FFZ6
names: Caution
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Phosphotriesterase family.
messages: Binds 2 divalent metal cations per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

263358:VAB18032 RS03535
gene id: 263358:VAB18032_RS03535
uniprot id: F4F244
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

263358:VAB18032 RS16675
gene id: 263358:VAB18032_RS16675
uniprot id: F4F3T7
names: Similarity
names: Subunit
messages: Belongs to the sigma-70 factor family. ECF subfamily.
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

263358:VAB18032 RS21250
gene id: 263358:VAB18032_RS21250
uniprot id: F4FGJ1
names: Subcellular Location Annotation
messages: Membrane

263358:VAB18032 RS24595
gene id: 263358:VAB18032_RS24595
uniprot id: F4F815
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

263358:VAB18032 RS02520
gene id: 263358:VAB18032_RS02520
uniprot id: F4FFV0
names: Similarity
messages: Belongs to the thioesterase family.

263358:VAB18032 RS26800
gene id: 263358:VAB18032_RS26800
uniprot id: F4FEI9
names: Similarity
messages: Belongs to the adenylyl cyclase class-3 family.

263358:VAB18032 RS10480
gene id: 263358:VAB18032_RS10480
uniprot id: F4F3L7
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

263358:VAB18032 RS28535
gene id: 263358:VAB18032_RS28535
uniprot id: F4F236
names: Similarity
messages: Belongs to the WXG100 family.

263358:VAB18032 RS06085
gene id: 263358:VAB18032_RS06085
uniprot id: F4F884
names: Similarity
messages: Belongs to the bacterial ring-hydroxylating dioxygenase beta subunit family.

263358:VAB18032 RS06165
gene id: 263358:VAB18032_RS06165
uniprot id: F4F899
names: Similarity
messages: Belongs to the glycosyl hydrolase 10 (cellulase F) family.

263358:VAB18032 RS20645
gene id: 263358:VAB18032_RS20645
uniprot id: F4FED4
names: Similarity
messages: Belongs to the CdaR family.

263358:VAB18032 RS15465
gene id: 263358:VAB18032_RS15465
uniprot id: F4FHH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

263358:VAB18032 RS25565
gene id: 263358:VAB18032_RS25565
uniprot id: F4FB39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

263358:VAB18032 RS23490
gene id: 263358:VAB18032_RS23490
uniprot id: F4F589
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

263358:VAB18032 RS14790
gene id: 263358:VAB18032_RS14790
uniprot id: F4FFA5
names: Similarity
messages: Belongs to the ribulokinase family.

263358:VAB18032 RS07425
gene id: 263358:VAB18032_RS07425
uniprot id: F4FBP5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

263358:VAB18032 RS18125
gene id: 263358:VAB18032_RS18125
uniprot id: F4F7P5
names: Subcellular Location Annotation
messages: Membrane

263358:VAB18032 RS26590
gene id: 263358:VAB18032_RS26590
uniprot id: F4FDH7
names: Subcellular Location Annotation
messages: Membrane

263358:VAB18032 RS04370
gene id: 263358:VAB18032_RS04370
uniprot id: F4F4E3
names: Similarity
messages: Belongs to the glycosyl hydrolase 25 family.

263358:VAB18032 RS21830
gene id: 263358:VAB18032_RS21830
uniprot id: F4FHS4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CobB/CobQ family. GatD subfamily.
messages: Forms a heterodimer with MurT.
messages: The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The GatD subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia. The resulting ammonia molecule is channeled to the active site of MurT.

263358:VAB18032 RS18035
gene id: 263358:VAB18032_RS18035
uniprot id: F4F7M8
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
messages: Cytoplasm
messages: The 20S proteasome core is composed of 14 alpha and 14 beta subunits that assemble into four stacked heptameric rings, resulting in a barrel-shaped structure. The two inner rings, each composed of seven catalytic beta subunits, are sandwiched by two outer rings, each composed of seven alpha subunits. The catalytic chamber with the active sites is on the inside of the barrel. Has a gated structure, the ends of the cylinder being occluded by the N-termini of the alpha-subunits. Is capped by the proteasome-associated ATPase, ARC.
messages: The formation of the proteasomal ATPase ARC-20S proteasome complex, likely via the docking of the C-termini of ARC into the intersubunit pockets in the alpha-rings, may trigger opening of the gate for substrate entry. Interconversion between the open-gate and close-gate conformations leads to a dynamic regulation of the 20S proteasome proteolysis activity.

263358:VAB18032 RS09215
gene id: 263358:VAB18032_RS09215
uniprot id: F4FH86
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

263358:VAB18032 RS15790
gene id: 263358:VAB18032_RS15790
uniprot id: F4F1I2
names: Subcellular Location Annotation
messages: Membrane

263358:VAB18032 RS23600
gene id: 263358:VAB18032_RS23600
uniprot id: F4F638
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

263358:VAB18032 RS00580
gene id: 263358:VAB18032_RS00580
uniprot id: F4FA80
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

263358:VAB18032 RS18260
gene id: 263358:VAB18032_RS18260
uniprot id: F4F7S3
names: Similarity
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Homohexamer. The oligomerization is ATP-dependent.

263358:VAB18032 RS01300
gene id: 263358:VAB18032_RS01300
uniprot id: F4FCF7
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

263358:VAB18032 RS02035
gene id: 263358:VAB18032_RS02035
uniprot id: F4FEN9
names: Similarity
messages: Belongs to the helicase family. RAD25/XPB subfamily.

263358:VAB18032 RS28245
gene id: 263358:VAB18032_RS28245
uniprot id: F4F1Y0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

263358:VAB18032 RS15215
gene id: 263358:VAB18032_RS15215
uniprot id: F4FGF8
names: Subcellular Location Annotation
messages: Membrane

263358:VAB18032 RS03245
gene id: 263358:VAB18032_RS03245
uniprot id: F4F121
names: Similarity
messages: Belongs to the barstar family.

263358:VAB18032 RS07660
gene id: 263358:VAB18032_RS07660
uniprot id: F4FCR0
names: Subcellular Location Annotation
messages: Membrane

263358:VAB18032 RS14650
gene id: 263358:VAB18032_RS14650
uniprot id: F4FF76
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

263358:VAB18032 RS01295
gene id: 263358:VAB18032_RS01295
uniprot id: F4FCF6
names: Subcellular Location Annotation
messages: Membrane

263358:VAB18032 RS04590
gene id: 263358:VAB18032_RS04590
uniprot id: F4F4I9
names: Similarity
messages: Belongs to the peptidase S66 family.

263358:VAB18032 RS02180
gene id: 263358:VAB18032_RS02180
uniprot id: F4FER8
names: Similarity
messages: Belongs to the CDP-glycerol glycerophosphotransferase family.

263358:VAB18032 RS07520
gene id: 263358:VAB18032_RS07520
uniprot id: F4FCN2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

263358:VAB18032 RS10175
gene id: 263358:VAB18032_RS10175
uniprot id: F4F2I7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

263358:VAB18032 RS25890
gene id: 263358:VAB18032_RS25890
uniprot id: F4FC70
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

263358:VAB18032 RS00770
gene id: 263358:VAB18032_RS00770
uniprot id: F4FAB8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

263358:VAB18032 RS11730
gene id: 263358:VAB18032_RS11730
uniprot id: F4F7E7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

263358:VAB18032 RS22215
gene id: 263358:VAB18032_RS22215
uniprot id: F4F1U6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

263358:VAB18032 RS15240
gene id: 263358:VAB18032_RS15240
uniprot id: F4FGG3
names: Cofactor
names: Similarity
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.

263358:VAB18032 RS07905
gene id: 263358:VAB18032_RS07905
uniprot id: F4FDS3
names: Similarity
messages: Belongs to the histone deacetylase family.

263358:VAB18032 RS13950
gene id: 263358:VAB18032_RS13950
uniprot id: F4FD08
names: Subcellular Location Annotation
messages: Membrane

263358:VAB18032 RS26840
gene id: 263358:VAB18032_RS26840
uniprot id: F4FEJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transcriptional regulatory Rex family.
messages: Cytoplasm
messages: Homodimer.
messages: Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.

263358:VAB18032 RS09185
gene id: 263358:VAB18032_RS09185
uniprot id: F4FH80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

263358:VAB18032 RS32620
gene id: 263358:VAB18032_RS32620
uniprot id: F4FA30
names: Cofactor
names: Function
messages: Binds 1 [3Fe-4S] cluster.
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

263358:VAB18032 RS02065
gene id: 263358:VAB18032_RS02065
uniprot id: F4FEP5
names: Function
names: Similarity
messages: Belongs to the PNP/UDP phosphorylase family. Futalosine hydrolase subfamily.
messages: Catalyzes the hydrolysis of futalosine (FL) to dehypoxanthine futalosine (DHFL) and hypoxanthine, a step in the biosynthesis of menaquinone (MK, vitamin K2).

263358:VAB18032 RS04810
gene id: 263358:VAB18032_RS04810
uniprot id: F4F5F7
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

263358:VAB18032 RS14815
gene id: 263358:VAB18032_RS14815
uniprot id: F4FFB0
names: Subcellular Location Annotation
messages: Membrane

263358:VAB18032 RS28265
gene id: 263358:VAB18032_RS28265
uniprot id: F4F1Y4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

263358:VAB18032 RS23755
gene id: 263358:VAB18032_RS23755
uniprot id: F4F669
names: Similarity
messages: Belongs to the acetaldehyde dehydrogenase family.

263358:VAB18032 RS26290
gene id: 263358:VAB18032_RS26290
uniprot id: F4FDB8
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

263358:VAB18032 RS14640
gene id: 263358:VAB18032_RS14640
uniprot id: F4FF74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic sulfate-binding protein family.
messages: Periplasm

263358:VAB18032 RS12110
gene id: 263358:VAB18032_RS12110
uniprot id: F4F7M3
names: Similarity
messages: Belongs to the AHA1 family.

263358:VAB18032 RS03970
gene id: 263358:VAB18032_RS03970
uniprot id: F4F398
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

263358:VAB18032 RS07920
gene id: 263358:VAB18032_RS07920
uniprot id: F4FDS6
names: Similarity
messages: Belongs to the AHA1 family.

263358:VAB18032 RS26105
gene id: 263358:VAB18032_RS26105
uniprot id: F4FCB3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

263358:VAB18032 RS01945
gene id: 263358:VAB18032_RS01945
uniprot id: F4FDQ2
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

263358:VAB18032 RS01615
gene id: 263358:VAB18032_RS01615
uniprot id: F4FCM0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 30 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

263358:VAB18032 RS26080
gene id: 263358:VAB18032_RS26080
uniprot id: F4FCA8
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

263358:VAB18032 RS08920
gene id: 263358:VAB18032_RS08920
uniprot id: F4FG61
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

263358:VAB18032 RS08770
gene id: 263358:VAB18032_RS08770
uniprot id: F4FG32
names: Subunit
messages: Homodimer.

263358:VAB18032 RS02115
gene id: 263358:VAB18032_RS02115
uniprot id: F4FEQ5
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.

263358:VAB18032 RS29305
gene id: 263358:VAB18032_RS29305
uniprot id: F4F4B9
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

263358:VAB18032 RS08300
gene id: 263358:VAB18032_RS08300
uniprot id: F4FEX1
names: Similarity
messages: Belongs to the stealth family.

263358:VAB18032 RS11985
gene id: 263358:VAB18032_RS11985
uniprot id: F4F7J8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

263358:VAB18032 RS28250
gene id: 263358:VAB18032_RS28250
uniprot id: F4F1Y1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

263358:VAB18032 RS22775
gene id: 263358:VAB18032_RS22775
uniprot id: F4F3Y6
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

263358:VAB18032 RS25280
gene id: 263358:VAB18032_RS25280
uniprot id: F4FA15
names: Subcellular Location Annotation
messages: Cytoplasm

263358:VAB18032 RS24285
gene id: 263358:VAB18032_RS24285
uniprot id: F4F763
names: Subcellular Location Annotation
messages: Membrane

263358:VAB18032 RS26135
gene id: 263358:VAB18032_RS26135
uniprot id: F4FCB9
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

263358:VAB18032 RS29595
gene id: 263358:VAB18032_RS29595
uniprot id: F4FI25
names: Similarity
messages: Belongs to the ParB family.

263358:VAB18032 RS14165
gene id: 263358:VAB18032_RS14165
uniprot id: F4FE14
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

263358:VAB18032 RS14260
gene id: 263358:VAB18032_RS14260
uniprot id: F4FE33
names: Subcellular Location Annotation
messages: Membrane

263358:VAB18032 RS02620
gene id: 263358:VAB18032_RS02620
uniprot id: F4FFX0
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

263358:VAB18032 RS28610
gene id: 263358:VAB18032_RS28610
uniprot id: F4F317
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CbxX/CfxQ family.
messages: Cytoplasm

263358:VAB18032 RS07490
gene id: 263358:VAB18032_RS07490
uniprot id: F4FCM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 87 family.
messages: Membrane

263358:VAB18032 RS24535
gene id: 263358:VAB18032_RS24535
uniprot id: F4F803
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

263358:VAB18032 RS30100
gene id: 263358:VAB18032_RS30100
uniprot id: F4FD00
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

263358:VAB18032 RS22955
gene id: 263358:VAB18032_RS22955
uniprot id: F4F423
names: Similarity
messages: Belongs to the YciI family.

263358:VAB18032 RS17275
gene id: 263358:VAB18032_RS17275
uniprot id: F4F5V2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

263358:VAB18032 RS26385
gene id: 263358:VAB18032_RS26385
uniprot id: F4FDD5
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

263358:VAB18032 RS23375
gene id: 263358:VAB18032_RS23375
uniprot id: F4F566
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

263358:VAB18032 RS26475
gene id: 263358:VAB18032_RS26475
uniprot id: F4FDF3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

263358:VAB18032 RS01670
gene id: 263358:VAB18032_RS01670
uniprot id: F4FDJ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

263358:VAB18032 RS08880
gene id: 263358:VAB18032_RS08880
uniprot id: F4FG53
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UreE family.
messages: Cytoplasm
messages: Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly.

263358:VAB18032 RS19870
gene id: 263358:VAB18032_RS19870
uniprot id: F4FC42
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

263358:VAB18032 RS04970
gene id: 263358:VAB18032_RS04970
uniprot id: F4F5I9
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

263358:VAB18032 RS11080
gene id: 263358:VAB18032_RS11080
uniprot id: F4F5N5
names: Similarity
messages: Belongs to the citrate synthase family.

263358:VAB18032 RS11960
gene id: 263358:VAB18032_RS11960
uniprot id: F4F7J3
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
messages: Part of the 50S ribosomal subunit.

263358:VAB18032 RS15750
gene id: 263358:VAB18032_RS15750
uniprot id: F4F1H4
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

263358:VAB18032 RS07130
gene id: 263358:VAB18032_RS07130
uniprot id: F4FBI5
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

263358:VAB18032 RS15455
gene id: 263358:VAB18032_RS15455
uniprot id: F4FHH3
names: Cofactor
names: Similarity
messages: Belongs to the peptidase S45 family.
messages: Binds 1 Ca(2+) ion per dimer.

263358:VAB18032 RS29415
gene id: 263358:VAB18032_RS29415
uniprot id: F4F5A6
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

263358:VAB18032 RS18385
gene id: 263358:VAB18032_RS18385
uniprot id: F4F7U8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
messages: Membrane

263358:VAB18032 RS10455
gene id: 263358:VAB18032_RS10455
uniprot id: F4F3L2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

263358:VAB18032 RS25760
gene id: 263358:VAB18032_RS25760
uniprot id: F4FB78
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

263358:VAB18032 RS15590
gene id: 263358:VAB18032_RS15590
uniprot id: F4FHK0
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

263358:VAB18032 RS25530
gene id: 263358:VAB18032_RS25530
uniprot id: F4FB32
names: Cofactor
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

263358:VAB18032 RS26265
gene id: 263358:VAB18032_RS26265
uniprot id: F4FDB3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

263358:VAB18032 RS15500
gene id: 263358:VAB18032_RS15500
uniprot id: F4FHI2
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

263358:VAB18032 RS15495
gene id: 263358:VAB18032_RS15495
uniprot id: F4FHI1
names: Similarity
messages: Belongs to the IucA/IucC family.

263358:VAB18032 RS05130
gene id: 263358:VAB18032_RS05130
uniprot id: F4F6A7
names: Cofactor
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 1 family.
messages: Binds 1 zinc ion per subunit.

263358:VAB18032 RS26120
gene id: 263358:VAB18032_RS26120
uniprot id: F4FCB6
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

263358:VAB18032 RS11075
gene id: 263358:VAB18032_RS11075
uniprot id: F4F5N4
names: Function
names: Similarity
messages: Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family.
messages: Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate.

263358:VAB18032 RS27220
gene id: 263358:VAB18032_RS27220
uniprot id: F4FFP2
names: Subcellular Location Annotation
messages: Membrane

263358:VAB18032 RS06605
gene id: 263358:VAB18032_RS06605
uniprot id: F4F9F4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

263358:VAB18032 RS19590
gene id: 263358:VAB18032_RS19590
uniprot id: F4FBY5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

263358:VAB18032 RS07610
gene id: 263358:VAB18032_RS07610
uniprot id: F4FCQ0
names: Similarity
messages: Belongs to the SAM hydrolase / SAM-dependent halogenase family.

263358:VAB18032 RS29070
gene id: 263358:VAB18032_RS29070
uniprot id: F4F472
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

263358:VAB18032 RS05680
gene id: 263358:VAB18032_RS05680
uniprot id: F4F7A9
names: Similarity
messages: Belongs to the F420H(2)-dependent quinone reductase family.

263358:VAB18032 RS24600
gene id: 263358:VAB18032_RS24600
uniprot id: F4F816
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

263358:VAB18032 RS29375
gene id: 263358:VAB18032_RS29375
uniprot id: F4F598
names: Similarity
messages: Belongs to the AP endonuclease 2 family.

263358:VAB18032 RS03480
gene id: 263358:VAB18032_RS03480
uniprot id: F4F168
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

263358:VAB18032 RS18725
gene id: 263358:VAB18032_RS18725
uniprot id: F4F8R3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

263358:VAB18032 RS24045
gene id: 263358:VAB18032_RS24045
uniprot id: F4F714
names: Subcellular Location Annotation
messages: Membrane

263358:VAB18032 RS24490
gene id: 263358:VAB18032_RS24490
uniprot id: F4F7Z4
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

263358:VAB18032 RS32700
gene id: 263358:VAB18032_RS32700
uniprot id: F4F271
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

263358:VAB18032 RS10300
gene id: 263358:VAB18032_RS10300
uniprot id: F4F3I0
names: Similarity
messages: Belongs to the glycosyl hydrolase 26 family.

263358:VAB18032 RS25550
gene id: 263358:VAB18032_RS25550
uniprot id: F4FB36
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

263358:VAB18032 RS19275
gene id: 263358:VAB18032_RS19275
uniprot id: F4FAV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

263358:VAB18032 RS14595
gene id: 263358:VAB18032_RS14595
uniprot id: F4FF65
names: Subcellular Location Annotation
messages: Membrane

263358:VAB18032 RS27340
gene id: 263358:VAB18032_RS27340
uniprot id: F4FFR8
names: Subcellular Location Annotation
messages: Membrane

263358:VAB18032 RS23275
gene id: 263358:VAB18032_RS23275
uniprot id: F4F546
names: Subcellular Location Annotation
messages: Membrane

263358:VAB18032 RS25460
gene id: 263358:VAB18032_RS25460
uniprot id: F4FA52
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

263358:VAB18032 RS18510
gene id: 263358:VAB18032_RS18510
uniprot id: F4F8L8
names: Subunit
messages: Homodimer.

263358:VAB18032 RS27760
gene id: 263358:VAB18032_RS27760
uniprot id: F4FGW8
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

263358:VAB18032 RS06035
gene id: 263358:VAB18032_RS06035
uniprot id: F4F875
names: Similarity
messages: Belongs to the peptidase S33 family.

263358:VAB18032 RS08185
gene id: 263358:VAB18032_RS08185
uniprot id: F4FDX9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

263358:VAB18032 RS19155
gene id: 263358:VAB18032_RS19155
uniprot id: F4F9W7
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

263358:VAB18032 RS22400
gene id: 263358:VAB18032_RS22400
uniprot id: F4F2U8
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

263358:VAB18032 RS02295
gene id: 263358:VAB18032_RS02295
uniprot id: F4FEU1
names: Similarity
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.

263358:VAB18032 RS10550
gene id: 263358:VAB18032_RS10550
uniprot id: F4F3N2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA-PH family.
messages: Cytoplasm

263358:VAB18032 RS28105
gene id: 263358:VAB18032_RS28105
uniprot id: F4FI05
names: Similarity
messages: Belongs to the NodU/CmcH family.

263358:VAB18032 RS25545
gene id: 263358:VAB18032_RS25545
uniprot id: F4FB35
names: Similarity
messages: Belongs to the LDH/MDH superfamily.

263358:VAB18032 RS29370
gene id: 263358:VAB18032_RS29370
uniprot id: F4F597
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

263358:VAB18032 RS03545
gene id: 263358:VAB18032_RS03545
uniprot id: F4F247
names: Similarity
messages: Belongs to the peptidase M17 family.

263358:VAB18032 RS26675
gene id: 263358:VAB18032_RS26675
uniprot id: F4FEG5
names: Similarity
messages: Belongs to the Nudix hydrolase family.

263358:VAB18032 RS02125
gene id: 263358:VAB18032_RS02125
uniprot id: F4FEQ7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
messages: Homodimer.

263358:VAB18032 RS07805
gene id: 263358:VAB18032_RS07805
uniprot id: F4FCU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polysaccharide lyase 1 family.
messages: Secreted

263358:VAB18032 RS22075
gene id: 263358:VAB18032_RS22075
uniprot id: F4F1R7
names: Similarity
messages: Belongs to the FAD-binding monooxygenase family.

263358:VAB18032 RS05070
gene id: 263358:VAB18032_RS05070
uniprot id: F4F5K9
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

263358:VAB18032 RS10095
gene id: 263358:VAB18032_RS10095
uniprot id: F4F2H1
names: Subcellular Location Annotation
messages: Membrane

263358:VAB18032 RS21125
gene id: 263358:VAB18032_RS21125
uniprot id: F4FFJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

263358:VAB18032 RS12710
gene id: 263358:VAB18032_RS12710
uniprot id: F4F9K9
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

263358:VAB18032 RS22435
gene id: 263358:VAB18032_RS22435
uniprot id: F4F2V5
names: Subcellular Location Annotation
messages: Membrane

263358:VAB18032 RS00130
gene id: 263358:VAB18032_RS00130
uniprot id: F4F922
names: Subcellular Location Annotation
messages: Cell membrane

263358:VAB18032 RS22240
gene id: 263358:VAB18032_RS22240
uniprot id: F4F1V1
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

263358:VAB18032 RS10850
gene id: 263358:VAB18032_RS10850
uniprot id: F4F4Q5
names: Subcellular Location Annotation
messages: Membrane

263358:VAB18032 RS15480
gene id: 263358:VAB18032_RS15480
uniprot id: F4FHH8
names: Similarity
messages: Belongs to the group II decarboxylase family.

263358:VAB18032 RS01855
gene id: 263358:VAB18032_RS01855
uniprot id: F4FDN4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

263358:VAB18032 RS12005
gene id: 263358:VAB18032_RS12005
uniprot id: F4F7K2
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

263358:VAB18032 RS00230
gene id: 263358:VAB18032_RS00230
uniprot id: F4F942
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

263358:VAB18032 RS13480
gene id: 263358:VAB18032_RS13480
uniprot id: F4FBU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

263358:VAB18032 RS24880
gene id: 263358:VAB18032_RS24880
uniprot id: F4F8W6
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

263358:VAB18032 RS06900
gene id: 263358:VAB18032_RS06900
uniprot id: F4FAH4
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.

263358:VAB18032 RS05140
gene id: 263358:VAB18032_RS05140
uniprot id: F4F6B0
names: Subcellular Location Annotation
messages: Membrane

263358:VAB18032 RS10500
gene id: 263358:VAB18032_RS10500
uniprot id: F4F3M1
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

263358:VAB18032 RS04475
gene id: 263358:VAB18032_RS04475
uniprot id: F4F4G4
names: Subcellular Location Annotation
messages: Membrane

263358:VAB18032 RS02130
gene id: 263358:VAB18032_RS02130
uniprot id: F4FEQ8
names: Subcellular Location Annotation
messages: Membrane

263358:VAB18032 RS21750
gene id: 263358:VAB18032_RS21750
uniprot id: F4FHQ8
names: Similarity
messages: Belongs to the YggT family.

263358:VAB18032 RS09430
gene id: 263358:VAB18032_RS09430
uniprot id: F4FHC9
names: Subcellular Location Annotation
messages: Membrane

263358:VAB18032 RS29535
gene id: 263358:VAB18032_RS29535
uniprot id: F4F5D1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

263358:VAB18032 RS07120
gene id: 263358:VAB18032_RS07120
uniprot id: F4FBI3
names: Similarity
messages: Belongs to the UPF0102 family.

263358:VAB18032 RS15210
gene id: 263358:VAB18032_RS15210
uniprot id: F4FGF7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

263358:VAB18032 RS21755
gene id: 263358:VAB18032_RS21755
uniprot id: F4FHQ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SepF family.
messages: Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
messages: Cytoplasm
messages: Homodimer. Interacts with FtsZ.

263358:VAB18032 RS18755
gene id: 263358:VAB18032_RS18755
uniprot id: F4F8R9
names: Function
names: Similarity
messages: Belongs to the glutamate--cysteine ligase type 2 family. EgtA subfamily.
messages: Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC). This compound is used as substrate for the biosynthesis of the low-molecular thiol compound ergothioneine.

263358:VAB18032 RS11675
gene id: 263358:VAB18032_RS11675
uniprot id: F4F6P7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

263358:VAB18032 RS19225
gene id: 263358:VAB18032_RS19225
uniprot id: F4FAU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polysaccharide lyase 1 family.
messages: Secreted

263358:VAB18032 RS13445
gene id: 263358:VAB18032_RS13445
uniprot id: F4FBT9
names: Similarity
messages: Belongs to the glycosyl hydrolase 30 family.

263358:VAB18032 RS10470
gene id: 263358:VAB18032_RS10470
uniprot id: F4F3L5
names: Similarity
messages: Belongs to the cytochrome P450 family.

263358:VAB18032 RS09030
gene id: 263358:VAB18032_RS09030
uniprot id: F4FG83
names: Subcellular Location Annotation
messages: Membrane

263358:VAB18032 RS21965
gene id: 263358:VAB18032_RS21965
uniprot id: F4F1P5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AP endonuclease 2 family.
messages: Binds 3 Zn(2+) ions.
messages: Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.

263358:VAB18032 RS04745
gene id: 263358:VAB18032_RS04745
uniprot id: F4F5E4
names: Subcellular Location Annotation
messages: Membrane

263358:VAB18032 RS29405
gene id: 263358:VAB18032_RS29405
uniprot id: F4F5A4
names: Similarity
messages: Belongs to the myo-inositol 1-phosphate synthase family.

263358:VAB18032 RS16330
gene id: 263358:VAB18032_RS16330
uniprot id: F4F2Q4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

263358:VAB18032 RS04535
gene id: 263358:VAB18032_RS04535
uniprot id: F4F4H8
names: Similarity
messages: Belongs to the peptidase S8 family.

263358:VAB18032 RS23910
gene id: 263358:VAB18032_RS23910
uniprot id: F4F6Y8
names: Function
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.

263358:VAB18032 RS10155
gene id: 263358:VAB18032_RS10155
uniprot id: F4F2I3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvB family.
messages: Forms a complex with RuvA.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.

263358:VAB18032 RS07695
gene id: 263358:VAB18032_RS07695
uniprot id: F4FCR7
names: Subcellular Location Annotation
messages: Membrane

263358:VAB18032 RS24295
gene id: 263358:VAB18032_RS24295
uniprot id: F4F765
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the xylose isomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

263358:VAB18032 RS26275
gene id: 263358:VAB18032_RS26275
uniprot id: F4FDB5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

263358:VAB18032 RS12935
gene id: 263358:VAB18032_RS12935
uniprot id: F4FAL7
names: Subcellular Location Annotation
messages: Membrane

263358:VAB18032 RS04385
gene id: 263358:VAB18032_RS04385
uniprot id: F4F4E6
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

263358:VAB18032 RS09155
gene id: 263358:VAB18032_RS09155
uniprot id: F4FH74
names: Caution
names: Similarity
messages: Belongs to the globin family. Two-domain flavohemoproteins subfamily.
messages: In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

263358:VAB18032 RS07720
gene id: 263358:VAB18032_RS07720
uniprot id: F4FCS2
names: Function
names: Similarity
messages: Belongs to the RNase Y family.
messages: Endoribonuclease that initiates mRNA decay.

263358:VAB18032 RS23610
gene id: 263358:VAB18032_RS23610
uniprot id: F4F640
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

263358:VAB18032 RS22360
gene id: 263358:VAB18032_RS22360
uniprot id: F4F2U0
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

263358:VAB18032 RS18915
gene id: 263358:VAB18032_RS18915
uniprot id: F4F9R8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

263358:VAB18032 RS03965
gene id: 263358:VAB18032_RS03965
uniprot id: F4F397
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

263358:VAB18032 RS07895
gene id: 263358:VAB18032_RS07895
uniprot id: F4FDS1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DtxR/MntR family.
messages: Cytoplasm
messages: Homodimer.

263358:VAB18032 RS22255
gene id: 263358:VAB18032_RS22255
uniprot id: F4F1V5
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

263358:VAB18032 RS09775
gene id: 263358:VAB18032_RS09775
uniprot id: F4F1E2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GmhB family.
messages: Cytoplasm

263358:VAB18032 RS07850
gene id: 263358:VAB18032_RS07850
uniprot id: F4FCU9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

263358:VAB18032 RS12590
gene id: 263358:VAB18032_RS12590
uniprot id: F4F9I4
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family.

263358:VAB18032 RS17210
gene id: 263358:VAB18032_RS17210
uniprot id: F4F508
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

263358:VAB18032 RS27930
gene id: 263358:VAB18032_RS27930
uniprot id: F4FHX0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

263358:VAB18032 RS09615
gene id: 263358:VAB18032_RS09615
uniprot id: F4F1A8
names: Similarity
messages: Belongs to the peptidase S33 family.

263358:VAB18032 RS05125
gene id: 263358:VAB18032_RS05125
uniprot id: F4F6A6
names: Subcellular Location Annotation
messages: Membrane

263358:VAB18032 RS11215
gene id: 263358:VAB18032_RS11215
uniprot id: F4F5R6
names: Similarity
messages: Belongs to the peptidase C40 family.

263358:VAB18032 RS19460
gene id: 263358:VAB18032_RS19460
uniprot id: F4FAZ4
names: Similarity
messages: Belongs to the Fur family.

263358:VAB18032 RS11950
gene id: 263358:VAB18032_RS11950
uniprot id: F4F7J1
names: Similarity
messages: Belongs to the Fur family.

263358:VAB18032 RS22430
gene id: 263358:VAB18032_RS22430
uniprot id: F4F2V4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glutamine synthetase family.
messages: Cytoplasm
messages: Oligomer of 12 subunits arranged in the form of two hexagons.

263358:VAB18032 RS18065
gene id: 263358:VAB18032_RS18065
uniprot id: F4F7N3
names: Similarity
names: Subunit
messages: Belongs to the AAA ATPase family.
messages: Homohexamer. Assembles into a hexameric ring structure.

263358:VAB18032 RS13630
gene id: 263358:VAB18032_RS13630
uniprot id: F4FBX6
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

263358:VAB18032 RS07690
gene id: 263358:VAB18032_RS07690
uniprot id: F4FCR6
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family.

263358:VAB18032 RS21210
gene id: 263358:VAB18032_RS21210
uniprot id: F4FGI3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

263358:VAB18032 RS11865
gene id: 263358:VAB18032_RS11865
uniprot id: F4F7H4
names: Subcellular Location Annotation
messages: Membrane

263358:VAB18032 RS10880
gene id: 263358:VAB18032_RS10880
uniprot id: F4F4R1
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

263358:VAB18032 RS17885
gene id: 263358:VAB18032_RS17885
uniprot id: F4F6V9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

263358:VAB18032 RS25310
gene id: 263358:VAB18032_RS25310
uniprot id: F4FA22
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type 2 tetrahydrodipicolinate N-succinyltransferase family.
messages: Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2-amino-6-oxopimelate using succinyl-CoA.
messages: Cytoplasm
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

263358:VAB18032 RS05415
gene id: 263358:VAB18032_RS05415
uniprot id: F4F6G4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell membrane
messages: Membrane

263358:VAB18032 RS26115
gene id: 263358:VAB18032_RS26115
uniprot id: F4FCB5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

263358:VAB18032 RS21895
gene id: 263358:VAB18032_RS21895
uniprot id: F4FHT7
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

263358:VAB18032 RS06890
gene id: 263358:VAB18032_RS06890
uniprot id: F4FAH3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

263358:VAB18032 RS02375
gene id: 263358:VAB18032_RS02375
uniprot id: F4FEV7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

263358:VAB18032 RS20280
gene id: 263358:VAB18032_RS20280
uniprot id: F4FD95
names: Similarity
messages: Belongs to the WrbA family.

263358:VAB18032 RS16400
gene id: 263358:VAB18032_RS16400
uniprot id: F4F2R8
names: Subcellular Location Annotation
messages: Membrane

263358:VAB18032 RS06455
gene id: 263358:VAB18032_RS06455
uniprot id: F4F9C4
names: Subcellular Location Annotation
messages: Membrane

263358:VAB18032 RS25405
gene id: 263358:VAB18032_RS25405
uniprot id: F4FA41
names: Similarity
messages: Belongs to the peptidase U62 family.

263358:VAB18032 RS07085
gene id: 263358:VAB18032_RS07085
uniprot id: F4FBH6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

263358:VAB18032 RS14960
gene id: 263358:VAB18032_RS14960
uniprot id: F4FGA6
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

263358:VAB18032 RS14855
gene id: 263358:VAB18032_RS14855
uniprot id: F4FFB8
names: Similarity
messages: Belongs to the glycosyl hydrolase 26 family.

263358:VAB18032 RS29315
gene id: 263358:VAB18032_RS29315
uniprot id: F4F4C1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

263358:VAB18032 RS05830
gene id: 263358:VAB18032_RS05830
uniprot id: F4F7D9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

263358:VAB18032 RS26215
gene id: 263358:VAB18032_RS26215
uniprot id: F4FCD5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

263358:VAB18032 RS05115
gene id: 263358:VAB18032_RS05115
uniprot id: F4F6A4
names: Similarity
messages: Belongs to the UPF0434 family.

263358:VAB18032 RS02430
gene id: 263358:VAB18032_RS02430
uniprot id: F4FFT2
names: Subcellular Location Annotation
messages: Membrane

263358:VAB18032 RS10650
gene id: 263358:VAB18032_RS10650
uniprot id: F4F4L8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

263358:VAB18032 RS17955
gene id: 263358:VAB18032_RS17955
uniprot id: F4F6X4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

263358:VAB18032 RS14980
gene id: 263358:VAB18032_RS14980
uniprot id: F4FGB0
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

263358:VAB18032 RS00860
gene id: 263358:VAB18032_RS00860
uniprot id: F4FBA1
names: Similarity
messages: Belongs to the ComB family.

263358:VAB18032 RS26295
gene id: 263358:VAB18032_RS26295
uniprot id: F4FDB9
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

263358:VAB18032 RS23035
gene id: 263358:VAB18032_RS23035
uniprot id: F4F436
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

263358:VAB18032 RS04595
gene id: 263358:VAB18032_RS04595
uniprot id: F4F4J0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

263358:VAB18032 RS14585
gene id: 263358:VAB18032_RS14585
uniprot id: F4FF61
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

263358:VAB18032 RS28305
gene id: 263358:VAB18032_RS28305
uniprot id: F4F1Z1
names: Subcellular Location Annotation
messages: Membrane

263358:VAB18032 RS11905
gene id: 263358:VAB18032_RS11905
uniprot id: F4F7I2
names: Similarity
messages: Belongs to the peptidase C56 family.

263358:VAB18032 RS06450
gene id: 263358:VAB18032_RS06450
uniprot id: F4F9C3
names: Similarity
messages: Belongs to the TPP enzyme family.

263358:VAB18032 RS15815
gene id: 263358:VAB18032_RS15815
uniprot id: F4F1I7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

263358:VAB18032 RS16005
gene id: 263358:VAB18032_RS16005
uniprot id: F4F1M5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

263358:VAB18032 RS07445
gene id: 263358:VAB18032_RS07445
uniprot id: F4FBP9
names: Subcellular Location Annotation
messages: Membrane

263358:VAB18032 RS08010
gene id: 263358:VAB18032_RS08010
uniprot id: F4FDU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

263358:VAB18032 RS26000
gene id: 263358:VAB18032_RS26000
uniprot id: F4FC92
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

263358:VAB18032 RS07630
gene id: 263358:VAB18032_RS07630
uniprot id: F4FCQ4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

263358:VAB18032 RS02210
gene id: 263358:VAB18032_RS02210
uniprot id: F4FES4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

263358:VAB18032 RS10530
gene id: 263358:VAB18032_RS10530
uniprot id: F4F3M8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.
messages: Belongs to the acyl-CoA oxidase family.

263358:VAB18032 RS25905
gene id: 263358:VAB18032_RS25905
uniprot id: F4FC73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
messages: Cell membrane
messages: Membrane

263358:VAB18032 RS01405
gene id: 263358:VAB18032_RS01405
uniprot id: F4FCH8
names: Subcellular Location Annotation
messages: Membrane

263358:VAB18032 RS17865
gene id: 263358:VAB18032_RS17865
uniprot id: F4F6V4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

263358:VAB18032 RS21265
gene id: 263358:VAB18032_RS21265
uniprot id: F4FGJ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

263358:VAB18032 RS12465
gene id: 263358:VAB18032_RS12465
uniprot id: F4F8J2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 independent methionine synthase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.

263358:VAB18032 RS16055
gene id: 263358:VAB18032_RS16055
uniprot id: F4F2J9
names: Similarity
messages: Belongs to the UPF0749 family.

263358:VAB18032 RS03565
gene id: 263358:VAB18032_RS03565
uniprot id: F4F251
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.
messages: In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: In the N-terminal section; belongs to the MIP18 family.

263358:VAB18032 RS28330
gene id: 263358:VAB18032_RS28330
uniprot id: F4F1Z6
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

263358:VAB18032 RS20080
gene id: 263358:VAB18032_RS20080
uniprot id: F4FD54
names: Similarity
messages: Belongs to the glutamate synthase family.

263358:VAB18032 RS10570
gene id: 263358:VAB18032_RS10570
uniprot id: F4F3N6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

263358:VAB18032 RS02405
gene id: 263358:VAB18032_RS02405
uniprot id: F4FEW3
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

263358:VAB18032 RS25815
gene id: 263358:VAB18032_RS25815
uniprot id: F4FB89
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

263358:VAB18032 RS28155
gene id: 263358:VAB18032_RS28155
uniprot id: F4FI16
names: Similarity
messages: Belongs to the clavaminate synthase family.

263358:VAB18032 RS01630
gene id: 263358:VAB18032_RS01630
uniprot id: F4FDI7
names: Function
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

263358:VAB18032 RS22405
gene id: 263358:VAB18032_RS22405
uniprot id: F4F2U9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 2 subfamily.
messages: Cytoplasm
messages: Homodimer.

263358:VAB18032 RS19820
gene id: 263358:VAB18032_RS19820
uniprot id: F4FC31
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

263358:VAB18032 RS02105
gene id: 263358:VAB18032_RS02105
uniprot id: F4FEQ3
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

263358:VAB18032 RS16060
gene id: 263358:VAB18032_RS16060
uniprot id: F4F2K0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sbp family.
messages: Cell membrane

263358:VAB18032 RS03910
gene id: 263358:VAB18032_RS03910
uniprot id: F4F387
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

263358:VAB18032 RS24520
gene id: 263358:VAB18032_RS24520
uniprot id: F4F800
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

263358:VAB18032 RS28270
gene id: 263358:VAB18032_RS28270
uniprot id: F4F1Y5
names: Similarity
messages: Belongs to the DnaX/STICHEL family.

263358:VAB18032 RS26865
gene id: 263358:VAB18032_RS26865
uniprot id: F4FEK2
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

263358:VAB18032 RS19670
gene id: 263358:VAB18032_RS19670
uniprot id: F4FC01
names: Function
names: Similarity
messages: ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.
messages: Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.

263358:VAB18032 RS06495
gene id: 263358:VAB18032_RS06495
uniprot id: F4F9D2
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

263358:VAB18032 RS18245
gene id: 263358:VAB18032_RS18245
uniprot id: F4F7R9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

263358:VAB18032 RS27915
gene id: 263358:VAB18032_RS27915
uniprot id: F4FHW7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

263358:VAB18032 RS13420
gene id: 263358:VAB18032_RS13420
uniprot id: F4FBT4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Acetyl-CoA carboxylase is a heterotetramer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits of ACCase subunit beta/alpha.
messages: Belongs to the AccA family.
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the AccA family.
messages: In the N-terminal section; belongs to the AccD/PCCB family.

263358:VAB18032 RS23130
gene id: 263358:VAB18032_RS23130
uniprot id: F4F517
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

263358:VAB18032 RS06460
gene id: 263358:VAB18032_RS06460
uniprot id: F4F9C5
names: Subcellular Location Annotation
messages: Membrane

263358:VAB18032 RS29000
gene id: 263358:VAB18032_RS29000
uniprot id: F4F458
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

263358:VAB18032 RS20530
gene id: 263358:VAB18032_RS20530
uniprot id: F4FEB1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

263358:VAB18032 RS28710
gene id: 263358:VAB18032_RS28710
uniprot id: F4F335
names: Similarity
messages: Belongs to the manganese catalase family.

263358:VAB18032 RS02310
gene id: 263358:VAB18032_RS02310
uniprot id: F4FEU4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane

263358:VAB18032 RS19300
gene id: 263358:VAB18032_RS19300
uniprot id: F4FAW0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

263358:VAB18032 RS01705
gene id: 263358:VAB18032_RS01705
uniprot id: F4FDK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EamA transporter family.
messages: Membrane

263358:VAB18032 RS20725
gene id: 263358:VAB18032_RS20725
uniprot id: F4FEF1
names: Subcellular Location Annotation
messages: Membrane

263358:VAB18032 RS05255
gene id: 263358:VAB18032_RS05255
uniprot id: F4F6D3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in cellular division.

263358:VAB18032 RS27435
gene id: 263358:VAB18032_RS27435
uniprot id: F4FGQ4
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

263358:VAB18032 RS19790
gene id: 263358:VAB18032_RS19790
uniprot id: F4FC25
names: Subcellular Location Annotation
messages: Membrane

263358:VAB18032 RS07150
gene id: 263358:VAB18032_RS07150
uniprot id: F4FBI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

263358:VAB18032 RS05235
gene id: 263358:VAB18032_RS05235
uniprot id: F4F6C9
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

263358:VAB18032 RS28840
gene id: 263358:VAB18032_RS28840
uniprot id: F4F360
names: Similarity
messages: Belongs to the Nudix hydrolase family.

263358:VAB18032 RS07470
gene id: 263358:VAB18032_RS07470
uniprot id: F4FBQ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

263358:VAB18032 RS21775
gene id: 263358:VAB18032_RS21775
uniprot id: F4FHR3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

263358:VAB18032 RS18765
gene id: 263358:VAB18032_RS18765
uniprot id: F4F8S1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

263358:VAB18032 RS24070
gene id: 263358:VAB18032_RS24070
uniprot id: F4F719
names: Similarity
messages: Belongs to the YciI family.

263358:VAB18032 RS10285
gene id: 263358:VAB18032_RS10285
uniprot id: F4F3H5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase MltG family.
messages: Cell membrane
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

263358:VAB18032 RS06170
gene id: 263358:VAB18032_RS06170
uniprot id: F4F8A0
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

263358:VAB18032 RS19880
gene id: 263358:VAB18032_RS19880
uniprot id: F4FC44
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

263358:VAB18032 RS03430
gene id: 263358:VAB18032_RS03430
uniprot id: F4F158
names: Similarity
messages: Belongs to the peptidase S1B family.

263358:VAB18032 RS26960
gene id: 263358:VAB18032_RS26960
uniprot id: F4FEM2
names: Function
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

263358:VAB18032 RS01480
gene id: 263358:VAB18032_RS01480
uniprot id: F4FCJ3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the radical SAM superfamily. MqnE family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3-[(1-carboxyvinyl)oxy]benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate.

263358:VAB18032 RS10370
gene id: 263358:VAB18032_RS10370
uniprot id: F4F3J5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm

263358:VAB18032 RS21080
gene id: 263358:VAB18032_RS21080
uniprot id: F4FFI9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
messages: Membrane

263358:VAB18032 RS14900
gene id: 263358:VAB18032_RS14900
uniprot id: F4FG94
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

263358:VAB18032 RS01100
gene id: 263358:VAB18032_RS01100
uniprot id: F4FBE6
names: Similarity
messages: Belongs to the glycosyl hydrolase 65 family.

263358:VAB18032 RS18935
gene id: 263358:VAB18032_RS18935
uniprot id: F4F9S2
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

263358:VAB18032 RS23750
gene id: 263358:VAB18032_RS23750
uniprot id: F4F668
names: Similarity
messages: Belongs to the 4-hydroxy-2-oxovalerate aldolase family.

263358:VAB18032 RS07940
gene id: 263358:VAB18032_RS07940
uniprot id: F4FDT0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

263358:VAB18032 RS07140
gene id: 263358:VAB18032_RS07140
uniprot id: F4FBI7
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

263358:VAB18032 RS19445
gene id: 263358:VAB18032_RS19445
uniprot id: F4FAZ1
names: Similarity
messages: Belongs to the peptidase S8 family.

263358:VAB18032 RS24410
gene id: 263358:VAB18032_RS24410
uniprot id: F4F7X7
names: Subunit
messages: Heterodimer of an alpha and a beta chain.

263358:VAB18032 RS22905
gene id: 263358:VAB18032_RS22905
uniprot id: F4F413
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

263358:VAB18032 RS10360
gene id: 263358:VAB18032_RS10360
uniprot id: F4F3J3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

263358:VAB18032 RS02195
gene id: 263358:VAB18032_RS02195
uniprot id: F4FES1
names: Similarity
messages: Belongs to the glycosyl hydrolase 65 family.

263358:VAB18032 RS23395
gene id: 263358:VAB18032_RS23395
uniprot id: F4F570
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

263358:VAB18032 RS05880
gene id: 263358:VAB18032_RS05880
uniprot id: F4F846
names: Subcellular Location Annotation
messages: Membrane

263358:VAB18032 RS12890
gene id: 263358:VAB18032_RS12890
uniprot id: F4F9P5
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

263358:VAB18032 RS23835
gene id: 263358:VAB18032_RS23835
uniprot id: F4F685
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

263358:VAB18032 RS21410
gene id: 263358:VAB18032_RS21410
uniprot id: F4FGM3
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

263358:VAB18032 RS05825
gene id: 263358:VAB18032_RS05825
uniprot id: F4F7D8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

263358:VAB18032 RS21140
gene id: 263358:VAB18032_RS21140
uniprot id: F4FGG8
names: Function
names: Similarity
messages: Belongs to the WhiA family.
messages: Involved in cell division and chromosome segregation.

263358:VAB18032 RS10855
gene id: 263358:VAB18032_RS10855
uniprot id: F4F4Q6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AlaDH/PNT family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reductive amination of pyruvate to L-alanine.

263358:VAB18032 RS21635
gene id: 263358:VAB18032_RS21635
uniprot id: F4FHN5
names: Similarity
messages: Belongs to the terpene synthase family.

263358:VAB18032 RS17370
gene id: 263358:VAB18032_RS17370
uniprot id: F4F5X1
names: Subcellular Location Annotation
messages: Membrane

263358:VAB18032 RS29355
gene id: 263358:VAB18032_RS29355
uniprot id: F4F594
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

263358:VAB18032 RS01475
gene id: 263358:VAB18032_RS01475
uniprot id: F4FCJ2
names: Similarity
messages: Belongs to the peptidase C40 family.

263358:VAB18032 RS08605
gene id: 263358:VAB18032_RS08605
uniprot id: F4FF28
names: Similarity
messages: Belongs to the universal stress protein A family.

263358:VAB18032 RS28135
gene id: 263358:VAB18032_RS28135
uniprot id: F4FI12
names: Subcellular Location Annotation
messages: Membrane

263358:VAB18032 RS14775
gene id: 263358:VAB18032_RS14775
uniprot id: F4FFA2
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

263358:VAB18032 RS18940
gene id: 263358:VAB18032_RS18940
uniprot id: F4F9S3
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

263358:VAB18032 RS00700
gene id: 263358:VAB18032_RS00700
uniprot id: F4FAA4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

263358:VAB18032 RS19625
gene id: 263358:VAB18032_RS19625
uniprot id: F4FBZ2
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

263358:VAB18032 RS11635
gene id: 263358:VAB18032_RS11635
uniprot id: F4F6N8
names: Subcellular Location Annotation
messages: Membrane

263358:VAB18032 RS29075
gene id: 263358:VAB18032_RS29075
uniprot id: F4F473
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily.

263358:VAB18032 RS25040
gene id: 263358:VAB18032_RS25040
uniprot id: F4F8Z9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.
messages: Cytoplasm

263358:VAB18032 RS21935
gene id: 263358:VAB18032_RS21935
uniprot id: F4F1N9
names: Similarity
messages: Belongs to the carotenoid/retinoid oxidoreductase family.

263358:VAB18032 RS13075
gene id: 263358:VAB18032_RS13075
uniprot id: F4FAP9
names: Similarity
messages: Belongs to the bacterial microcompartments protein family.

263358:VAB18032 RS07075
gene id: 263358:VAB18032_RS07075
uniprot id: F4FAK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

263358:VAB18032 RS27695
gene id: 263358:VAB18032_RS27695
uniprot id: F4FGV5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DisA family.
messages: Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP likely acts as a signaling molecule that may couple DNA integrity with a cellular process.
messages: Homooctamer.
messages: Participates in a DNA-damage check-point. DisA forms globular foci that rapidly scan along the chromosomes searching for lesions.

263358:VAB18032 RS12310
gene id: 263358:VAB18032_RS12310
uniprot id: F4F8G1
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

263358:VAB18032 RS23350
gene id: 263358:VAB18032_RS23350
uniprot id: F4F561
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

263358:VAB18032 RS08400
gene id: 263358:VAB18032_RS08400
uniprot id: F4FEZ2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

263358:VAB18032 RS24670
gene id: 263358:VAB18032_RS24670
uniprot id: F4F830
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

263358:VAB18032 RS23880
gene id: 263358:VAB18032_RS23880
uniprot id: F4F694
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SURF1 family.
messages: Cell membrane

263358:VAB18032 RS15900
gene id: 263358:VAB18032_RS15900
uniprot id: F4F1K4
names: Similarity
messages: Belongs to the PrpD family.

263358:VAB18032 RS14550
gene id: 263358:VAB18032_RS14550
uniprot id: F4FF54
names: Function
names: Similarity
messages: Belongs to the catalase family. HPII subfamily.
messages: Serves to protect cells from the toxic effects of hydrogen peroxide.

263358:VAB18032 RS26375
gene id: 263358:VAB18032_RS26375
uniprot id: F4FDD2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

263358:VAB18032 RS07580
gene id: 263358:VAB18032_RS07580
uniprot id: F4FCP4
names: Similarity
messages: Belongs to the PspA/IM30 family.

263358:VAB18032 RS24710
gene id: 263358:VAB18032_RS24710
uniprot id: F4F8T3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

263358:VAB18032 RS26195
gene id: 263358:VAB18032_RS26195
uniprot id: F4FCD1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

263358:VAB18032 RS11820
gene id: 263358:VAB18032_RS11820
uniprot id: F4F7G5
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

263358:VAB18032 RS01060
gene id: 263358:VAB18032_RS01060
uniprot id: F4FBD8
names: Subcellular Location Annotation
messages: Membrane

263358:VAB18032 RS25945
gene id: 263358:VAB18032_RS25945
uniprot id: F4FC81
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

263358:VAB18032 RS21760
gene id: 263358:VAB18032_RS21760
uniprot id: F4FHR0
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

263358:VAB18032 RS04420
gene id: 263358:VAB18032_RS04420
uniprot id: F4F4F3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.
messages: Cytoplasm
messages: Monomer.

263358:VAB18032 RS20690
gene id: 263358:VAB18032_RS20690
uniprot id: F4FEE4
names: Similarity
names: Subunit
messages: Belongs to the sigma-70 factor family. ECF subfamily.
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

263358:VAB18032 RS04065
gene id: 263358:VAB18032_RS04065
uniprot id: F4F3B7
names: Subcellular Location Annotation
messages: Membrane

263358:VAB18032 RS04190
gene id: 263358:VAB18032_RS04190
uniprot id: F4F3E2
names: Similarity
messages: Belongs to the UPRTase family.

263358:VAB18032 RS25105
gene id: 263358:VAB18032_RS25105
uniprot id: F4F9Y1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

263358:VAB18032 RS10450
gene id: 263358:VAB18032_RS10450
uniprot id: F4F3L1
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

263358:VAB18032 RS04285
gene id: 263358:VAB18032_RS04285
uniprot id: F4F3G1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

263358:VAB18032 RS21875
gene id: 263358:VAB18032_RS21875
uniprot id: F4FHT3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

263358:VAB18032 RS27665
gene id: 263358:VAB18032_RS27665
uniprot id: F4FGU9
names: Similarity
messages: Belongs to the thiolase-like superfamily. Chalcone/stilbene synthases family.

263358:VAB18032 RS16325
gene id: 263358:VAB18032_RS16325
uniprot id: F4F2Q3
names: Similarity
messages: Belongs to the glutamate synthase family.

263358:VAB18032 RS27020
gene id: 263358:VAB18032_RS27020
uniprot id: F4FFK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

263358:VAB18032 RS06480
gene id: 263358:VAB18032_RS06480
uniprot id: F4F9C9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ETF beta-subunit/FixA family.
messages: Heterodimer of an alpha and a beta subunit.
messages: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

263358:VAB18032 RS29505
gene id: 263358:VAB18032_RS29505
uniprot id: F4F5C4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

263358:VAB18032 RS05000
gene id: 263358:VAB18032_RS05000
uniprot id: F4F5J5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

263358:VAB18032 RS29455
gene id: 263358:VAB18032_RS29455
uniprot id: F4F5B4
names: Similarity
messages: Belongs to the thioredoxin family.

263358:VAB18032 RS13325
gene id: 263358:VAB18032_RS13325
uniprot id: F4FBR5
names: Subcellular Location Annotation
messages: Membrane

263358:VAB18032 RS20445
gene id: 263358:VAB18032_RS20445
uniprot id: F4FE93
names: Similarity
messages: Belongs to the Nudix hydrolase family.

263358:VAB18032 RS23190
gene id: 263358:VAB18032_RS23190
uniprot id: F4F529
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of glycine to tRNA(Gly).
messages: Cytoplasm
messages: Homodimer.

263358:VAB18032 RS28545
gene id: 263358:VAB18032_RS28545
uniprot id: F4F238
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EccB family.
messages: Membrane

263358:VAB18032 RS27645
gene id: 263358:VAB18032_RS27645
uniprot id: F4FGU5
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

263358:VAB18032 RS27015
gene id: 263358:VAB18032_RS27015
uniprot id: F4FEN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

263358:VAB18032 RS20685
gene id: 263358:VAB18032_RS20685
uniprot id: F4FEE3
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

263358:VAB18032 RS25155
gene id: 263358:VAB18032_RS25155
uniprot id: F4F9Z1
names: Similarity
messages: Belongs to the SAICAR synthetase family.

263358:VAB18032 RS26190
gene id: 263358:VAB18032_RS26190
uniprot id: F4FCD0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

263358:VAB18032 RS28555
gene id: 263358:VAB18032_RS28555
uniprot id: F4F308
names: Similarity
messages: Belongs to the EccD/Snm4 family.

263358:VAB18032 RS11495
gene id: 263358:VAB18032_RS11495
uniprot id: F4F6K9
names: Similarity
messages: Belongs to the group II decarboxylase family.

263358:VAB18032 RS10445
gene id: 263358:VAB18032_RS10445
uniprot id: F4F3L0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

263358:VAB18032 RS03990
gene id: 263358:VAB18032_RS03990
uniprot id: F4F3A2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. GalK subfamily.
messages: Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P).
messages: Cytoplasm

263358:VAB18032 RS00950
gene id: 263358:VAB18032_RS00950
uniprot id: F4FBB9
names: Similarity
messages: Belongs to the AHA1 family.

263358:VAB18032 RS16270
gene id: 263358:VAB18032_RS16270
uniprot id: F4F2P2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

263358:VAB18032 RS09050
gene id: 263358:VAB18032_RS09050
uniprot id: F4FH53
names: Subcellular Location Annotation
messages: Membrane

263358:VAB18032 RS00485
gene id: 263358:VAB18032_RS00485
uniprot id: F4FA59
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

263358:VAB18032 RS09930
gene id: 263358:VAB18032_RS09930
uniprot id: F4F2D9
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

263358:VAB18032 RS22225
gene id: 263358:VAB18032_RS22225
uniprot id: F4F1U8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with subunits I, II and III to form cytochrome c oxidase.
messages: Belongs to the cytochrome c oxidase bacterial subunit CtaF family.
messages: Cell membrane
messages: Membrane
messages: Part of cytochrome c oxidase, its function is unknown.

263358:VAB18032 RS24580
gene id: 263358:VAB18032_RS24580
uniprot id: F4F812
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

263358:VAB18032 RS15485
gene id: 263358:VAB18032_RS15485
uniprot id: F4FHH9
names: Similarity
messages: Belongs to the lysine N(6)-hydroxylase/L-ornithine N(5)-oxygenase family.

263358:VAB18032 RS09435
gene id: 263358:VAB18032_RS09435
uniprot id: F4FHD0
names: Subcellular Location Annotation
messages: Membrane

263358:VAB18032 RS26300
gene id: 263358:VAB18032_RS26300
uniprot id: F4FDC0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

263358:VAB18032 RS04805
gene id: 263358:VAB18032_RS04805
uniprot id: F4F5F6
names: Similarity
messages: Belongs to the serine/threonine dehydratase family.

263358:VAB18032 RS15880
gene id: 263358:VAB18032_RS15880
uniprot id: F4F1K0
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

263358:VAB18032 RS03890
gene id: 263358:VAB18032_RS03890
uniprot id: F4F2B8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Monomer.

263358:VAB18032 RS25630
gene id: 263358:VAB18032_RS25630
uniprot id: F4FB52
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

263358:VAB18032 RS02320
gene id: 263358:VAB18032_RS02320
uniprot id: F4FEU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0060 family.
messages: Cell membrane

263358:VAB18032 RS15810
gene id: 263358:VAB18032_RS15810
uniprot id: F4F1I6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell inner membrane
messages: Membrane

263358:VAB18032 RS00850
gene id: 263358:VAB18032_RS00850
uniprot id: F4FB99
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

263358:VAB18032 RS21770
gene id: 263358:VAB18032_RS21770
uniprot id: F4FHR2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsQ/DivIB family. FtsQ subfamily.
messages: Cell membrane
messages: Essential cell division protein.

263358:VAB18032 RS26030
gene id: 263358:VAB18032_RS26030
uniprot id: F4FC98
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

263358:VAB18032 RS13010
gene id: 263358:VAB18032_RS13010
uniprot id: F4FAN6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

263358:VAB18032 RS01795
gene id: 263358:VAB18032_RS01795
uniprot id: F4FDM0
names: Subcellular Location Annotation
messages: Membrane

263358:VAB18032 RS25100
gene id: 263358:VAB18032_RS25100
uniprot id: F4F9Y0
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

263358:VAB18032 RS13980
gene id: 263358:VAB18032_RS13980
uniprot id: F4FD14
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

263358:VAB18032 RS27735
gene id: 263358:VAB18032_RS27735
uniprot id: F4FGW3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

263358:VAB18032 RS02775
gene id: 263358:VAB18032_RS02775
uniprot id: F4FG01
names: Similarity
messages: Belongs to the YciI family.

263358:VAB18032 RS14450
gene id: 263358:VAB18032_RS14450
uniprot id: F4FE70
names: Similarity
messages: Belongs to the malate synthase family.

263358:VAB18032 RS32125
gene id: 263358:VAB18032_RS32125
uniprot id: F4FHD7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

263358:VAB18032 RS26315
gene id: 263358:VAB18032_RS26315
uniprot id: F4FDC2
names: Similarity
messages: Belongs to the UPF0336 family.

263358:VAB18032 RS04210
gene id: 263358:VAB18032_RS04210
uniprot id: F4F3E6
names: Subunit
messages: Heterodimer of an alpha and a beta chain.

263358:VAB18032 RS09490
gene id: 263358:VAB18032_RS09490
uniprot id: F4F183
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

263358:VAB18032 RS14690
gene id: 263358:VAB18032_RS14690
uniprot id: F4FF84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

263358:VAB18032 RS05770
gene id: 263358:VAB18032_RS05770
uniprot id: F4F7C7
names: Subcellular Location Annotation
messages: Membrane

263358:VAB18032 RS07110
gene id: 263358:VAB18032_RS07110
uniprot id: F4FBI1
names: Similarity
messages: Belongs to the DprA/Smf family.

263358:VAB18032 RS23765
gene id: 263358:VAB18032_RS23765
uniprot id: F4F671
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

263358:VAB18032 RS09355
gene id: 263358:VAB18032_RS09355
uniprot id: F4FHB4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
messages: Monomer.

263358:VAB18032 RS13530
gene id: 263358:VAB18032_RS13530
uniprot id: F4FBV6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the faeC family.
messages: Involved in degradation of plant cell walls. Hydrolyzes the feruloyl-arabinose ester bond in arabinoxylans, and the feruloyl-galactose ester bond in pectin. Active against paranitrophenyl-acetate, methyl ferulate and wheat arabinoxylan.
messages: Secreted

263358:VAB18032 RS25215
gene id: 263358:VAB18032_RS25215
uniprot id: F4FA02
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

263358:VAB18032 RS00980
gene id: 263358:VAB18032_RS00980
uniprot id: F4FBC2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IPP isomerase type 1 family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium ion binds only when substrate is bound.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).
messages: Cytoplasm

263358:VAB18032 RS01175
gene id: 263358:VAB18032_RS01175
uniprot id: F4FBG3
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

263358:VAB18032 RS11815
gene id: 263358:VAB18032_RS11815
uniprot id: F4F7G4
names: Similarity
messages: Belongs to the cytochrome P450 family.

263358:VAB18032 RS27280
gene id: 263358:VAB18032_RS27280
uniprot id: F4FFQ5
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

263358:VAB18032 RS25295
gene id: 263358:VAB18032_RS25295
uniprot id: F4FA18
names: Similarity
messages: Belongs to the LOG family.

263358:VAB18032 RS23535
gene id: 263358:VAB18032_RS23535
uniprot id: F4F628
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

263358:VAB18032 RS17185
gene id: 263358:VAB18032_RS17185
uniprot id: F4F503
names: Subcellular Location Annotation
messages: Membrane

263358:VAB18032 RS26280
gene id: 263358:VAB18032_RS26280
uniprot id: F4FDB6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

263358:VAB18032 RS25880
gene id: 263358:VAB18032_RS25880
uniprot id: F4FC68
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

263358:VAB18032 RS16255
gene id: 263358:VAB18032_RS16255
uniprot id: F4F2N9
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.
messages: Monomer.

263358:VAB18032 RS06945
gene id: 263358:VAB18032_RS06945
uniprot id: F4FAI3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

263358:VAB18032 RS03785
gene id: 263358:VAB18032_RS03785
uniprot id: F4F296
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MetX family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

263358:VAB18032 RS07665
gene id: 263358:VAB18032_RS07665
uniprot id: F4FCR1
names: Subcellular Location Annotation
messages: Membrane

263358:VAB18032 RS11860
gene id: 263358:VAB18032_RS11860
uniprot id: F4F7H3
names: Subcellular Location Annotation
messages: Membrane

263358:VAB18032 RS21945
gene id: 263358:VAB18032_RS21945
uniprot id: F4F1P1
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

263358:VAB18032 RS09680
gene id: 263358:VAB18032_RS09680
uniprot id: F4F1C3
names: Similarity
messages: Belongs to the pirin family.

263358:VAB18032 RS07250
gene id: 263358:VAB18032_RS07250
uniprot id: F4FBK9
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

263358:VAB18032 RS21345
gene id: 263358:VAB18032_RS21345
uniprot id: F4FGL1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

263358:VAB18032 RS17685
gene id: 263358:VAB18032_RS17685
uniprot id: F4F6R9
names: Function
names: Subcellular Location Annotation
messages: Iron-sulfur subunit of the cytochrome bc1 complex, an essential component of the respiratory electron transport chain required for ATP synthesis. The bc1 complex catalyzes the oxidation of menaquinol and the reduction of cytochrome c in the respiratory chain. The bc1 complex operates through a Q-cycle mechanism that couples electron transfer to generation of the proton gradient that drives ATP synthesis.
messages: Membrane

263358:VAB18032 RS17115
gene id: 263358:VAB18032_RS17115
uniprot id: F4F4Y9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpC family.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

263358:VAB18032 RS28185
gene id: 263358:VAB18032_RS28185
uniprot id: F4F1W8
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase class-III family.

263358:VAB18032 RS02705
gene id: 263358:VAB18032_RS02705
uniprot id: F4FFY7
names: Similarity
messages: Belongs to the NtaA/SnaA/DszA monooxygenase family.

263358:VAB18032 RS09015
gene id: 263358:VAB18032_RS09015
uniprot id: F4FG80
names: Subcellular Location Annotation
messages: Membrane

263358:VAB18032 RS14870
gene id: 263358:VAB18032_RS14870
uniprot id: F4FG88
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

263358:VAB18032 RS04120
gene id: 263358:VAB18032_RS04120
uniprot id: F4F3C8
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

263358:VAB18032 RS06665
gene id: 263358:VAB18032_RS06665
uniprot id: F4F9G6
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

263358:VAB18032 RS03675
gene id: 263358:VAB18032_RS03675
uniprot id: F4F274
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Membrane

263358:VAB18032 RS08855
gene id: 263358:VAB18032_RS08855
uniprot id: F4FG48
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

263358:VAB18032 RS08625
gene id: 263358:VAB18032_RS08625
uniprot id: F4FF32
names: Subcellular Location Annotation
messages: Membrane

263358:VAB18032 RS05425
gene id: 263358:VAB18032_RS05425
uniprot id: F4F6G6
names: Similarity
messages: Belongs to the F420H(2)-dependent quinone reductase family.

263358:VAB18032 RS29550
gene id: 263358:VAB18032_RS29550
uniprot id: F4F5D4
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

263358:VAB18032 RS19390
gene id: 263358:VAB18032_RS19390
uniprot id: F4FAX9
names: Similarity
messages: Belongs to the glycosyl hydrolase 67 family.

263358:VAB18032 RS21300
gene id: 263358:VAB18032_RS21300
uniprot id: F4FGK1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the UPF0157 (GrpB) family.
messages: In the N-terminal section; belongs to the CoaE family.

263358:VAB18032 RS08590
gene id: 263358:VAB18032_RS08590
uniprot id: F4FF25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

263358:VAB18032 RS13345
gene id: 263358:VAB18032_RS13345
uniprot id: F4FBR9
names: Similarity
messages: Belongs to the asparagine synthetase family.

263358:VAB18032 RS17395
gene id: 263358:VAB18032_RS17395
uniprot id: F4F5X6
names: Similarity
messages: Belongs to the threonine aldolase family.

263358:VAB18032 RS24140
gene id: 263358:VAB18032_RS24140
uniprot id: F4F733
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

263358:VAB18032 RS19920
gene id: 263358:VAB18032_RS19920
uniprot id: F4FC52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

263358:VAB18032 RS03505
gene id: 263358:VAB18032_RS03505
uniprot id: F4F173
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

263358:VAB18032 RS20850
gene id: 263358:VAB18032_RS20850
uniprot id: F4FFE3
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

263358:VAB18032 RS23620
gene id: 263358:VAB18032_RS23620
uniprot id: F4F642
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

263358:VAB18032 RS10675
gene id: 263358:VAB18032_RS10675
uniprot id: F4F4M3
names: Similarity
messages: Belongs to the DNA glycosylase MPG family.

263358:VAB18032 RS18415
gene id: 263358:VAB18032_RS18415
uniprot id: F4F7V4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

263358:VAB18032 RS17475
gene id: 263358:VAB18032_RS17475
uniprot id: F4F5Z2
names: Similarity
messages: Belongs to the TPP enzyme family.

263358:VAB18032 RS24335
gene id: 263358:VAB18032_RS24335
uniprot id: F4F7W2
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

263358:VAB18032 RS21570
gene id: 263358:VAB18032_RS21570
uniprot id: F4FHM3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

263358:VAB18032 RS21680
gene id: 263358:VAB18032_RS21680
uniprot id: F4FHP3
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

263358:VAB18032 RS27955
gene id: 263358:VAB18032_RS27955
uniprot id: F4FHX5
names: Subcellular Location Annotation
messages: Membrane

263358:VAB18032 RS08595
gene id: 263358:VAB18032_RS08595
uniprot id: F4FF26
names: Similarity
messages: Belongs to the universal stress protein A family.

263358:VAB18032 RS04435
gene id: 263358:VAB18032_RS04435
uniprot id: F4F4F6
names: Function
names: Similarity
messages: Belongs to the trehalose phosphatase family.
messages: Removes the phosphate from trehalose 6-phosphate to produce free trehalose.

263358:VAB18032 RS08655
gene id: 263358:VAB18032_RS08655
uniprot id: F4FF39
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

263358:VAB18032 RS21670
gene id: 263358:VAB18032_RS21670
uniprot id: F4FHP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

263358:VAB18032 RS13620
gene id: 263358:VAB18032_RS13620
uniprot id: F4FBX4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
messages: Belongs to the azoreductase type 1 family.
messages: Binds 1 FMN per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones.

263358:VAB18032 RS18810
gene id: 263358:VAB18032_RS18810
uniprot id: F4F9P7
names: Subcellular Location Annotation
messages: Membrane

263358:VAB18032 RS21985
gene id: 263358:VAB18032_RS21985
uniprot id: F4F1P9
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family.

263358:VAB18032 RS01225
gene id: 263358:VAB18032_RS01225
uniprot id: F4FBH3
names: Subcellular Location Annotation
messages: Membrane

263358:VAB18032 RS10700
gene id: 263358:VAB18032_RS10700
uniprot id: F4F4M8
names: Similarity
messages: Belongs to the universal stress protein A family.

263358:VAB18032 RS06675
gene id: 263358:VAB18032_RS06675
uniprot id: F4FAD5
names: Function
names: Similarity
messages: Belongs to the ApbE family.
messages: Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.

263358:VAB18032 RS26125
gene id: 263358:VAB18032_RS26125
uniprot id: F4FCB7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

263358:VAB18032 RS26270
gene id: 263358:VAB18032_RS26270
uniprot id: F4FDB4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

263358:VAB18032 RS09180
gene id: 263358:VAB18032_RS09180
uniprot id: F4FH79
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the faeC family.
messages: Involved in degradation of plant cell walls. Hydrolyzes the feruloyl-arabinose ester bond in arabinoxylans, and the feruloyl-galactose ester bond in pectin. Active against paranitrophenyl-acetate, methyl ferulate and wheat arabinoxylan.
messages: Secreted

263358:VAB18032 RS12165
gene id: 263358:VAB18032_RS12165
uniprot id: F4F8C9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

263358:VAB18032 RS15025
gene id: 263358:VAB18032_RS15025
uniprot id: F4FGC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EccB family.
messages: Membrane

263358:VAB18032 RS26430
gene id: 263358:VAB18032_RS26430
uniprot id: F4FDE4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

263358:VAB18032 RS00845
gene id: 263358:VAB18032_RS00845
uniprot id: F4FAD3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

263358:VAB18032 RS06390
gene id: 263358:VAB18032_RS06390
uniprot id: F4F9B1
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

263358:VAB18032 RS04070
gene id: 263358:VAB18032_RS04070
uniprot id: F4F3B8
names: Subcellular Location Annotation
messages: Membrane

263358:VAB18032 RS13610
gene id: 263358:VAB18032_RS13610
uniprot id: F4FBX2
names: Similarity
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.

263358:VAB18032 RS21035
gene id: 263358:VAB18032_RS21035
uniprot id: F4FFI0
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.

263358:VAB18032 RS28340
gene id: 263358:VAB18032_RS28340
uniprot id: F4F1Z8
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

263358:VAB18032 RS14975
gene id: 263358:VAB18032_RS14975
uniprot id: F4FGA9
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

263358:VAB18032 RS25850
gene id: 263358:VAB18032_RS25850
uniprot id: F4FB96
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

263358:VAB18032 RS26360
gene id: 263358:VAB18032_RS26360
uniprot id: F4FDC9
names: Similarity
messages: Belongs to the UPF0234 family.

263358:VAB18032 RS01680
gene id: 263358:VAB18032_RS01680
uniprot id: F4FDJ7
names: Subcellular Location Annotation
messages: Membrane

263358:VAB18032 RS29420
gene id: 263358:VAB18032_RS29420
uniprot id: F4F5A7
names: Similarity
messages: Belongs to the peptidase S8 family.

263358:VAB18032 RS26405
gene id: 263358:VAB18032_RS26405
uniprot id: F4FDD9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

263358:VAB18032 RS11700
gene id: 263358:VAB18032_RS11700
uniprot id: F4F6Q2
names: Similarity
messages: Belongs to the thioesterase family.

263358:VAB18032 RS08270
gene id: 263358:VAB18032_RS08270
uniprot id: F4FEW5
names: Similarity
names: Subunit
messages: Belongs to the sigma-70 factor family. ECF subfamily.
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

263358:VAB18032 RS12645
gene id: 263358:VAB18032_RS12645
uniprot id: F4F9J6
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

263358:VAB18032 RS03185
gene id: 263358:VAB18032_RS03185
uniprot id: F4FH48
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

263358:VAB18032 RS22350
gene id: 263358:VAB18032_RS22350
uniprot id: F4F2T8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

263358:VAB18032 RS05075
gene id: 263358:VAB18032_RS05075
uniprot id: F4F5L0
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

263358:VAB18032 RS09300
gene id: 263358:VAB18032_RS09300
uniprot id: F4FHA3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

263358:VAB18032 RS02000
gene id: 263358:VAB18032_RS02000
uniprot id: F4FDR3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic Ku family.
messages: Homodimer. Interacts with LigD.
messages: With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD.

263358:VAB18032 RS21575
gene id: 263358:VAB18032_RS21575
uniprot id: F4FHM4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

263358:VAB18032 RS23605
gene id: 263358:VAB18032_RS23605
uniprot id: F4F639
names: Caution
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

263358:VAB18032 RS08055
gene id: 263358:VAB18032_RS08055
uniprot id: F4FDV3
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

263358:VAB18032 RS09825
gene id: 263358:VAB18032_RS09825
uniprot id: F4F1F2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

263358:VAB18032 RS08155
gene id: 263358:VAB18032_RS08155
uniprot id: F4FDX3
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

263358:VAB18032 RS04180
gene id: 263358:VAB18032_RS04180
uniprot id: F4F3E0
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

263358:VAB18032 RS20900
gene id: 263358:VAB18032_RS20900
uniprot id: F4FFF3
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

263358:VAB18032 RS10635
gene id: 263358:VAB18032_RS10635
uniprot id: F4F4L5
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

263358:VAB18032 RS11975
gene id: 263358:VAB18032_RS11975
uniprot id: F4F7J6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

263358:VAB18032 RS13430
gene id: 263358:VAB18032_RS13430
uniprot id: F4FBT6
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

263358:VAB18032 RS13315
gene id: 263358:VAB18032_RS13315
uniprot id: F4FBR3
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

263358:VAB18032 RS00400
gene id: 263358:VAB18032_RS00400
uniprot id: F4F975
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

263358:VAB18032 RS21115
gene id: 263358:VAB18032_RS21115
uniprot id: F4FFJ6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase-binding protein RbpA family.
messages: Bind 1 Zn(2+) per subunit.
messages: Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters.
messages: Forms a complex with the RNAP catalytic core and with free principal sigma factors.

263358:VAB18032 RS12995
gene id: 263358:VAB18032_RS12995
uniprot id: F4FAN3
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

263358:VAB18032 RS26415
gene id: 263358:VAB18032_RS26415
uniprot id: F4FDE1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

263358:VAB18032 RS18110
gene id: 263358:VAB18032_RS18110
uniprot id: F4F7P2
names: Subcellular Location Annotation
messages: Membrane

263358:VAB18032 RS25625
gene id: 263358:VAB18032_RS25625
uniprot id: F4FB51
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

263358:VAB18032 RS23495
gene id: 263358:VAB18032_RS23495
uniprot id: F4F590
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

263358:VAB18032 RS01975
gene id: 263358:VAB18032_RS01975
uniprot id: F4FDQ8
names: Similarity
messages: Belongs to the Nudix hydrolase family.

263358:VAB18032 RS21120
gene id: 263358:VAB18032_RS21120
uniprot id: F4FFJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Membrane

263358:VAB18032 RS28010
gene id: 263358:VAB18032_RS28010
uniprot id: F4FHY6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

263358:VAB18032 RS25825
gene id: 263358:VAB18032_RS25825
uniprot id: F4FB91
names: Subcellular Location Annotation
messages: Membrane

263358:VAB18032 RS15875
gene id: 263358:VAB18032_RS15875
uniprot id: F4F1J9
names: Similarity
messages: Belongs to the TPP enzyme family.

263358:VAB18032 RS07145
gene id: 263358:VAB18032_RS07145
uniprot id: F4FBI8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

263358:VAB18032 RS17770
gene id: 263358:VAB18032_RS17770
uniprot id: F4F6T6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease gamma subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

263358:VAB18032 RS20245
gene id: 263358:VAB18032_RS20245
uniprot id: F4FD88
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

263358:VAB18032 RS16180
gene id: 263358:VAB18032_RS16180
uniprot id: F4F2M4
names: Subcellular Location Annotation
messages: Membrane

263358:VAB18032 RS01380
gene id: 263358:VAB18032_RS01380
uniprot id: F4FCH3
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

263358:VAB18032 RS16225
gene id: 263358:VAB18032_RS16225
uniprot id: F4F2N3
names: Similarity
messages: Belongs to the FAD-binding monooxygenase family.

263358:VAB18032 RS24665
gene id: 263358:VAB18032_RS24665
uniprot id: F4F829
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

263358:VAB18032 RS21085
gene id: 263358:VAB18032_RS21085
uniprot id: F4FFJ0
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Homodimer.

263358:VAB18032 RS07635
gene id: 263358:VAB18032_RS07635
uniprot id: F4FCQ5
names: Subcellular Location Annotation
messages: Membrane

263358:VAB18032 RS01730
gene id: 263358:VAB18032_RS01730
uniprot id: F4FDK7
names: Similarity
messages: Belongs to the WXG100 family.

263358:VAB18032 RS02305
gene id: 263358:VAB18032_RS02305
uniprot id: F4FEU3
names: Subcellular Location Annotation
messages: Cell membrane

263358:VAB18032 RS10380
gene id: 263358:VAB18032_RS10380
uniprot id: F4F3J7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

263358:VAB18032 RS20570
gene id: 263358:VAB18032_RS20570
uniprot id: F4FEB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

263358:VAB18032 RS20775
gene id: 263358:VAB18032_RS20775
uniprot id: F4FFC5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

263358:VAB18032 RS20705
gene id: 263358:VAB18032_RS20705
uniprot id: F4FEE7
names: Similarity
messages: Belongs to the TPP enzyme family.

263358:VAB18032 RS21565
gene id: 263358:VAB18032_RS21565
uniprot id: F4FHM2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

263358:VAB18032 RS19180
gene id: 263358:VAB18032_RS19180
uniprot id: F4F9X2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

263358:VAB18032 RS29495
gene id: 263358:VAB18032_RS29495
uniprot id: F4F5C2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

263358:VAB18032 RS22490
gene id: 263358:VAB18032_RS22490
uniprot id: F4F2W6
names: Similarity
messages: Belongs to the glutamine synthetase family.

263358:VAB18032 RS03765
gene id: 263358:VAB18032_RS03765
uniprot id: F4F292
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

263358:VAB18032 RS10695
gene id: 263358:VAB18032_RS10695
uniprot id: F4F4M7
names: Similarity
messages: Belongs to the universal stress protein A family.

263358:VAB18032 RS07035
gene id: 263358:VAB18032_RS07035
uniprot id: F4FAK1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
messages: Consists of three domains: the N-terminal catalytic domain, the anticodon-binding domain and the C-terminal extension.
messages: Cytoplasm
messages: Homodimer.

263358:VAB18032 RS11980
gene id: 263358:VAB18032_RS11980
uniprot id: F4F7J7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

263358:VAB18032 RS12145
gene id: 263358:VAB18032_RS12145
uniprot id: F4F8C5
names: Similarity
messages: Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family.

263358:VAB18032 RS04165
gene id: 263358:VAB18032_RS04165
uniprot id: F4F3D7
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

263358:VAB18032 RS24660
gene id: 263358:VAB18032_RS24660
uniprot id: F4F828
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

263358:VAB18032 RS19185
gene id: 263358:VAB18032_RS19185
uniprot id: F4F9X3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

263358:VAB18032 RS01640
gene id: 263358:VAB18032_RS01640
uniprot id: F4FDI9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

263358:VAB18032 RS24270
gene id: 263358:VAB18032_RS24270
uniprot id: F4F760
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

263358:VAB18032 RS25115
gene id: 263358:VAB18032_RS25115
uniprot id: F4F9Y3
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

263358:VAB18032 RS04160
gene id: 263358:VAB18032_RS04160
uniprot id: F4F3D6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Membrane

263358:VAB18032 RS27390
gene id: 263358:VAB18032_RS27390
uniprot id: F4FFS8
names: Similarity
messages: Belongs to the AAA ATPase family.

263358:VAB18032 RS20095
gene id: 263358:VAB18032_RS20095
uniprot id: F4FD57
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

263358:VAB18032 RS28195
gene id: 263358:VAB18032_RS28195
uniprot id: F4F1X0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

263358:VAB18032 RS19050
gene id: 263358:VAB18032_RS19050
uniprot id: F4F9U5
names: Similarity
messages: Belongs to the myoviridae tail sheath protein family.

263358:VAB18032 RS21100
gene id: 263358:VAB18032_RS21100
uniprot id: F4FFJ3
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

263358:VAB18032 RS01840
gene id: 263358:VAB18032_RS01840
uniprot id: F4FDN0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-insensitive subfamily.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force.

263358:VAB18032 RS13410
gene id: 263358:VAB18032_RS13410
uniprot id: F4FBT2
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

263358:VAB18032 RS25780
gene id: 263358:VAB18032_RS25780
uniprot id: F4FB82
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cell surface
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
messages: capsule
messages: cell wall

263358:VAB18032 RS10225
gene id: 263358:VAB18032_RS10225
uniprot id: F4F2J8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.

263358:VAB18032 RS23230
gene id: 263358:VAB18032_RS23230
uniprot id: F4F537
names: Similarity
messages: Belongs to the Fur family.

263358:VAB18032 RS22385
gene id: 263358:VAB18032_RS22385
uniprot id: F4F2U5
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

263358:VAB18032 RS23550
gene id: 263358:VAB18032_RS23550
uniprot id: F4F631
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

263358:VAB18032 RS05260
gene id: 263358:VAB18032_RS05260
uniprot id: F4F6D4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

263358:VAB18032 RS12915
gene id: 263358:VAB18032_RS12915
uniprot id: F4FAL3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

263358:VAB18032 RS26855
gene id: 263358:VAB18032_RS26855
uniprot id: F4FEK0
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

263358:VAB18032 RS28585
gene id: 263358:VAB18032_RS28585
uniprot id: F4F312
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S8 family.
messages: Cell membrane
messages: Membrane

263358:VAB18032 RS06880
gene id: 263358:VAB18032_RS06880
uniprot id: F4FAH1
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

263358:VAB18032 RS28790
gene id: 263358:VAB18032_RS28790
uniprot id: F4F349
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

263358:VAB18032 RS23650
gene id: 263358:VAB18032_RS23650
uniprot id: F4F647
names: Similarity
messages: Belongs to the peptidase S8 family.

263358:VAB18032 RS25225
gene id: 263358:VAB18032_RS25225
uniprot id: F4FA04
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

263358:VAB18032 RS27605
gene id: 263358:VAB18032_RS27605
uniprot id: F4FGT7
names: Function
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: May catalyze the transamination reaction in phenylalanine biosynthesis.

263358:VAB18032 RS15095
gene id: 263358:VAB18032_RS15095
uniprot id: F4FGD4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PstS family.
messages: Part of the ABC transporter complex PstSACB involved in phosphate import.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

263358:VAB18032 RS21990
gene id: 263358:VAB18032_RS21990
uniprot id: F4F1Q0
names: Similarity
messages: Belongs to the glutathione peroxidase family.

263358:VAB18032 RS16020
gene id: 263358:VAB18032_RS16020
uniprot id: F4F1M8
names: Caution
names: Similarity
messages: Belongs to the globin family. Two-domain flavohemoproteins subfamily.
messages: In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

263358:VAB18032 RS14820
gene id: 263358:VAB18032_RS14820
uniprot id: F4FFB1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the arabinose isomerase family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the conversion of L-arabinose to L-ribulose.

263358:VAB18032 RS05065
gene id: 263358:VAB18032_RS05065
uniprot id: F4F5K8
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

263358:VAB18032 RS01580
gene id: 263358:VAB18032_RS01580
uniprot id: F4FCL3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the radical SAM superfamily. MqnC family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2).

263358:VAB18032 RS26395
gene id: 263358:VAB18032_RS26395
uniprot id: F4FDD7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

263358:VAB18032 RS12290
gene id: 263358:VAB18032_RS12290
uniprot id: F4F8F7
names: Subcellular Location Annotation
messages: Membrane

263358:VAB18032 RS21795
gene id: 263358:VAB18032_RS21795
uniprot id: F4FHR7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

263358:VAB18032 RS14615
gene id: 263358:VAB18032_RS14615
uniprot id: F4FF69
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

263358:VAB18032 RS26145
gene id: 263358:VAB18032_RS26145
uniprot id: F4FCC1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

263358:VAB18032 RS05270
gene id: 263358:VAB18032_RS05270
uniprot id: F4F6D6
names: Similarity
messages: Belongs to the TPP enzyme family.

263358:VAB18032 RS05765
gene id: 263358:VAB18032_RS05765
uniprot id: F4F7C6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
messages: Membrane

263358:VAB18032 RS16630
gene id: 263358:VAB18032_RS16630
uniprot id: F4F3S8
names: Similarity
messages: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family.

263358:VAB18032 RS13855
gene id: 263358:VAB18032_RS13855
uniprot id: F4FCY9
names: Subcellular Location Annotation
messages: Membrane

263358:VAB18032 RS06485
gene id: 263358:VAB18032_RS06485
uniprot id: F4F9D0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Heterodimer of an alpha and a beta subunit.
messages: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

263358:VAB18032 RS23460
gene id: 263358:VAB18032_RS23460
uniprot id: F4F583
names: Similarity
messages: Belongs to the peptidase M1 family.

263358:VAB18032 RS29345
gene id: 263358:VAB18032_RS29345
uniprot id: F4F4C7
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

263358:VAB18032 RS10145
gene id: 263358:VAB18032_RS10145
uniprot id: F4F2I1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RuvC family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.

263358:VAB18032 RS06660
gene id: 263358:VAB18032_RS06660
uniprot id: F4F9G5
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

263358:VAB18032 RS27120
gene id: 263358:VAB18032_RS27120
uniprot id: F4FFM1
names: Similarity
messages: Belongs to the Fur family.

263358:VAB18032 RS01720
gene id: 263358:VAB18032_RS01720
uniprot id: F4FDK5
names: Similarity
messages: Belongs to the EccE family.

263358:VAB18032 RS23155
gene id: 263358:VAB18032_RS23155
uniprot id: F4F522
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.

263358:VAB18032 RS10565
gene id: 263358:VAB18032_RS10565
uniprot id: F4F3N5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-3 family.
messages: Cytoplasm
messages: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
messages: Monomer.

263358:VAB18032 RS22035
gene id: 263358:VAB18032_RS22035
uniprot id: F4F1Q9
names: Caution
names: Cofactor
names: Function
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Exonuclease that cleaves single-stranded 3' overhangs of double-stranded RNA.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

263358:VAB18032 RS29450
gene id: 263358:VAB18032_RS29450
uniprot id: F4F5B3
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

263358:VAB18032 RS21765
gene id: 263358:VAB18032_RS21765
uniprot id: F4FHR1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

263358:VAB18032 RS21725
gene id: 263358:VAB18032_RS21725
uniprot id: F4FHQ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

263358:VAB18032 RS26245
gene id: 263358:VAB18032_RS26245
uniprot id: F4FCE1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

263358:VAB18032 RS25045
gene id: 263358:VAB18032_RS25045
uniprot id: F4F901
names: Function
messages: Catalyzes the reduction of sulfite to sulfide, a step in the biosynthesis of sulfur-containing amino acids and cofactors.

263358:VAB18032 RS09605
gene id: 263358:VAB18032_RS09605
uniprot id: F4F1A6
names: Similarity
messages: Belongs to the glycosyl hydrolase 9 (cellulase E) family.

263358:VAB18032 RS22825
gene id: 263358:VAB18032_RS22825
uniprot id: F4F3Z6
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

263358:VAB18032 RS28785
gene id: 263358:VAB18032_RS28785
uniprot id: F4F348
names: Caution
names: Similarity
messages: Belongs to the globin family. Two-domain flavohemoproteins subfamily.
messages: In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

263358:VAB18032 RS26820
gene id: 263358:VAB18032_RS26820
uniprot id: F4FEJ3
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

263358:VAB18032 RS27740
gene id: 263358:VAB18032_RS27740
uniprot id: F4FGW4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

263358:VAB18032 RS08730
gene id: 263358:VAB18032_RS08730
uniprot id: F4FG22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SsgA family.
messages: Cell septum

263358:VAB18032 RS25655
gene id: 263358:VAB18032_RS25655
uniprot id: F4FB57
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

263358:VAB18032 RS00820
gene id: 263358:VAB18032_RS00820
uniprot id: F4FAC8
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

263358:VAB18032 RS05245
gene id: 263358:VAB18032_RS05245
uniprot id: F4F6D1
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF2.
messages: Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.

263358:VAB18032 RS18720
gene id: 263358:VAB18032_RS18720
uniprot id: F4F8R2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the etk/wzc family.
messages: Cell inner membrane
messages: Membrane

263358:VAB18032 RS06865
gene id: 263358:VAB18032_RS06865
uniprot id: F4FAG8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

263358:VAB18032 RS25675
gene id: 263358:VAB18032_RS25675
uniprot id: F4FB61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

263358:VAB18032 RS00590
gene id: 263358:VAB18032_RS00590
uniprot id: F4FA82
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

263358:VAB18032 RS21835
gene id: 263358:VAB18032_RS21835
uniprot id: F4FHS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Membrane

263358:VAB18032 RS05795
gene id: 263358:VAB18032_RS05795
uniprot id: F4F7D2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ClpS family.
messages: Binds to the N-terminal domain of the chaperone ClpA.
messages: Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.

263358:VAB18032 RS19815
gene id: 263358:VAB18032_RS19815
uniprot id: F4FC30
names: Similarity
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.

263358:VAB18032 RS26140
gene id: 263358:VAB18032_RS26140
uniprot id: F4FCC0
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

263358:VAB18032 RS23450
gene id: 263358:VAB18032_RS23450
uniprot id: F4F581
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein L14 (rplN).

263358:VAB18032 RS26100
gene id: 263358:VAB18032_RS26100
uniprot id: F4FCB2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

263358:VAB18032 RS07460
gene id: 263358:VAB18032_RS07460
uniprot id: F4FBQ2
names: Similarity
messages: Belongs to the ribF family.

263358:VAB18032 RS04005
gene id: 263358:VAB18032_RS04005
uniprot id: F4F3A5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

263358:VAB18032 RS29360
gene id: 263358:VAB18032_RS29360
uniprot id: F4F595
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

263358:VAB18032 RS00475
gene id: 263358:VAB18032_RS00475
uniprot id: F4FA57
names: Function
names: Similarity
messages: Belongs to the RlpA family.
messages: Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.

263358:VAB18032 RS25495
gene id: 263358:VAB18032_RS25495
uniprot id: F4FB25
names: Subcellular Location Annotation
messages: Membrane

263358:VAB18032 RS04880
gene id: 263358:VAB18032_RS04880
uniprot id: F4F5H1
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

263358:VAB18032 RS01070
gene id: 263358:VAB18032_RS01070
uniprot id: F4FBE0
names: Similarity
messages: Belongs to the GSP E family.

263358:VAB18032 RS07060
gene id: 263358:VAB18032_RS07060
uniprot id: F4FAK6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

263358:VAB18032 RS10355
gene id: 263358:VAB18032_RS10355
uniprot id: F4F3J2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Monomer.

263358:VAB18032 RS08000
gene id: 263358:VAB18032_RS08000
uniprot id: F4FDU2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pseudouridine-5'-phosphate glycosidase family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the reversible cleavage of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway.
messages: Homotrimer.

263358:VAB18032 RS05135
gene id: 263358:VAB18032_RS05135
uniprot id: F4F6A8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

263358:VAB18032 RS10520
gene id: 263358:VAB18032_RS10520
uniprot id: F4F3M6
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

263358:VAB18032 RS02545
gene id: 263358:VAB18032_RS02545
uniprot id: F4FFV5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

263358:VAB18032 RS05055
gene id: 263358:VAB18032_RS05055
uniprot id: F4F5K6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M15D family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide.

263358:VAB18032 RS08940
gene id: 263358:VAB18032_RS08940
uniprot id: F4FG65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

263358:VAB18032 RS09980
gene id: 263358:VAB18032_RS09980
uniprot id: F4F2E9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glutaminase PdxT/SNO family.
messages: Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.
messages: In the presence of PdxS, forms a dodecamer of heterodimers. Only shows activity in the heterodimer.

263358:VAB18032 RS21175
gene id: 263358:VAB18032_RS21175
uniprot id: F4FGH6
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

263358:VAB18032 RS20830
gene id: 263358:VAB18032_RS20830
uniprot id: F4FFD9
names: Similarity
messages: Belongs to the asparagine synthetase family.

263358:VAB18032 RS17705
gene id: 263358:VAB18032_RS17705
uniprot id: F4F6S3
names: Subcellular Location Annotation
messages: Membrane

263358:VAB18032 RS23280
gene id: 263358:VAB18032_RS23280
uniprot id: F4F547
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

263358:VAB18032 RS05395
gene id: 263358:VAB18032_RS05395
uniprot id: F4F6G0
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

263358:VAB18032 RS16070
gene id: 263358:VAB18032_RS16070
uniprot id: F4F2K2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

263358:VAB18032 RS21190
gene id: 263358:VAB18032_RS21190
uniprot id: F4FGH9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

263358:VAB18032 RS23780
gene id: 263358:VAB18032_RS23780
uniprot id: F4F674
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tryptophan 2,3-dioxygenase family.
messages: Binds 1 heme group per subunit.
messages: Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L-tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

263358:VAB18032 RS07215
gene id: 263358:VAB18032_RS07215
uniprot id: F4FBK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

263358:VAB18032 RS02485
gene id: 263358:VAB18032_RS02485
uniprot id: F4FFU3
names: Similarity
messages: Belongs to the cytochrome P450 family.

263358:VAB18032 RS25860
gene id: 263358:VAB18032_RS25860
uniprot id: F4FB98
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

263358:VAB18032 RS08025
gene id: 263358:VAB18032_RS08025
uniprot id: F4FDU7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

263358:VAB18032 RS13920
gene id: 263358:VAB18032_RS13920
uniprot id: F4FD02
names: Similarity
messages: Belongs to the cytochrome P450 family.

263358:VAB18032 RS01420
gene id: 263358:VAB18032_RS01420
uniprot id: F4FCI1
names: Similarity
messages: Belongs to the UbiD family.

263358:VAB18032 RS20820
gene id: 263358:VAB18032_RS20820
uniprot id: F4FFD7
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

263358:VAB18032 RS16065
gene id: 263358:VAB18032_RS16065
uniprot id: F4F2K1
names: Similarity
messages: Belongs to the UPF0749 family.

263358:VAB18032 RS07415
gene id: 263358:VAB18032_RS07415
uniprot id: F4FBP3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

263358:VAB18032 RS09565
gene id: 263358:VAB18032_RS09565
uniprot id: F4F198
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

263358:VAB18032 RS04795
gene id: 263358:VAB18032_RS04795
uniprot id: F4F5F4
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

263358:VAB18032 RS01285
gene id: 263358:VAB18032_RS01285
uniprot id: F4FCF4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

263358:VAB18032 RS22230
gene id: 263358:VAB18032_RS22230
uniprot id: F4F1U9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Binds a copper A center.
messages: Cell membrane
messages: Membrane
messages: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).

263358:VAB18032 RS28650
gene id: 263358:VAB18032_RS28650
uniprot id: F4F323
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NiCoT transporter (TC 2.A.52) family.
messages: Cell membrane
messages: Membrane

263358:VAB18032 RS26320
gene id: 263358:VAB18032_RS26320
uniprot id: F4FDC3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

263358:VAB18032 RS13895
gene id: 263358:VAB18032_RS13895
uniprot id: F4FCZ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

263358:VAB18032 RS16905
gene id: 263358:VAB18032_RS16905
uniprot id: F4F4U6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

263358:VAB18032 RS26885
gene id: 263358:VAB18032_RS26885
uniprot id: F4FEK7
names: Subcellular Location Annotation
messages: Membrane

263358:VAB18032 RS11170
gene id: 263358:VAB18032_RS11170
uniprot id: F4F5Q6
names: Similarity
messages: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family.

263358:VAB18032 RS17075
gene id: 263358:VAB18032_RS17075
uniprot id: F4F4Y2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

263358:VAB18032 RS29240
gene id: 263358:VAB18032_RS29240
uniprot id: F4F4A6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

263358:VAB18032 RS27025
gene id: 263358:VAB18032_RS27025
uniprot id: F4FFK1
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

263358:VAB18032 RS10015
gene id: 263358:VAB18032_RS10015
uniprot id: F4F2F6
names: Subcellular Location Annotation
messages: Membrane

263358:VAB18032 RS12855
gene id: 263358:VAB18032_RS12855
uniprot id: F4F9N8
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

263358:VAB18032 RS18475
gene id: 263358:VAB18032_RS18475
uniprot id: F4F8K9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 2 subfamily.
messages: Cytoplasm
messages: Homotetramer.

263358:VAB18032 RS26130
gene id: 263358:VAB18032_RS26130
uniprot id: F4FCB8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

263358:VAB18032 RS08420
gene id: 263358:VAB18032_RS08420
uniprot id: F4FEZ6
names: Similarity
messages: Belongs to the glycosyl hydrolase 9 (cellulase E) family.

263358:VAB18032 RS13130
gene id: 263358:VAB18032_RS13130
uniprot id: F4FAR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

263358:VAB18032 RS07950
gene id: 263358:VAB18032_RS07950
uniprot id: F4FDT2
names: Similarity
messages: Belongs to the peptidase S8 family.

263358:VAB18032 RS28810
gene id: 263358:VAB18032_RS28810
uniprot id: F4F353
names: Similarity
messages: Belongs to the UPF0098 family.

263358:VAB18032 RS06650
gene id: 263358:VAB18032_RS06650
uniprot id: F4F9G3
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

263358:VAB18032 RS07785
gene id: 263358:VAB18032_RS07785
uniprot id: F4FCT6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the selenophosphate synthase 1 family. Class I subfamily.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Homodimer.
messages: Synthesizes selenophosphate from selenide and ATP.

263358:VAB18032 RS04015
gene id: 263358:VAB18032_RS04015
uniprot id: F4F3A7
names: Subcellular Location Annotation
messages: Membrane

263358:VAB18032 RS12475
gene id: 263358:VAB18032_RS12475
uniprot id: F4F8J4
names: Subcellular Location Annotation
messages: Membrane

263358:VAB18032 RS21690
gene id: 263358:VAB18032_RS21690
uniprot id: F4FHP6
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

263358:VAB18032 RS26205
gene id: 263358:VAB18032_RS26205
uniprot id: F4FCD3
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

263358:VAB18032 RS24570
gene id: 263358:VAB18032_RS24570
uniprot id: F4F810
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

263358:VAB18032 RS04095
gene id: 263358:VAB18032_RS04095
uniprot id: F4F3C3
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of adenosine and 2-deoxyadenosine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

263358:VAB18032 RS26565
gene id: 263358:VAB18032_RS26565
uniprot id: F4FDH1
names: Subcellular Location Annotation
messages: Membrane

263358:VAB18032 RS15400
gene id: 263358:VAB18032_RS15400
uniprot id: F4FHG0
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.

263358:VAB18032 RS27080
gene id: 263358:VAB18032_RS27080
uniprot id: F4FFL3
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.

263358:VAB18032 RS00165
gene id: 263358:VAB18032_RS00165
uniprot id: F4F929
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

263358:VAB18032 RS24980
gene id: 263358:VAB18032_RS24980
uniprot id: F4F8Y6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

263358:VAB18032 RS26165
gene id: 263358:VAB18032_RS26165
uniprot id: F4FCC5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

263358:VAB18032 RS17110
gene id: 263358:VAB18032_RS17110
uniprot id: F4F4Y8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system and for the release of the potassium ions to the cytoplasm.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

263358:VAB18032 RS22195
gene id: 263358:VAB18032_RS22195
uniprot id: F4F1U2
names: Caution
names: PTM
names: Subcellular Location Annotation
names: Subunit
messages: Binds 2 heme c groups covalently per subunit.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The cytochrome bc1 complex is composed of a cytochrome b (QcrB), the Rieske iron-sulfur protein (QcrA) and a diheme cytochrome c (QcrC) subunit.

263358:VAB18032 RS26835
gene id: 263358:VAB18032_RS26835
uniprot id: F4FEJ6
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

263358:VAB18032 RS21580
gene id: 263358:VAB18032_RS21580
uniprot id: F4FHM5
names: Similarity
messages: Belongs to the TrpC family.

263358:VAB18032 RS10510
gene id: 263358:VAB18032_RS10510
uniprot id: F4F3M3
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

263358:VAB18032 RS22770
gene id: 263358:VAB18032_RS22770
uniprot id: F4F3Y5
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

263358:VAB18032 RS11725
gene id: 263358:VAB18032_RS11725
uniprot id: G1C879
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

263358:VAB18032 RS26085
gene id: 263358:VAB18032_RS26085
uniprot id: F4FCA9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

263358:VAB18032 RS20115
gene id: 263358:VAB18032_RS20115
uniprot id: F4FD61
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

263358:VAB18032 RS13250
gene id: 263358:VAB18032_RS13250
uniprot id: F4FAT5
names: Similarity
messages: Belongs to the antibiotic N-acetyltransferase family.

263358:VAB18032 RS21260
gene id: 263358:VAB18032_RS21260
uniprot id: F4FGJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Membrane

263358:VAB18032 RS27795
gene id: 263358:VAB18032_RS27795
uniprot id: F4FHU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

263358:VAB18032 RS01655
gene id: 263358:VAB18032_RS01655
uniprot id: F4FDJ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

263358:VAB18032 RS26450
gene id: 263358:VAB18032_RS26450
uniprot id: F4FDE8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

263358:VAB18032 RS21780
gene id: 263358:VAB18032_RS21780
uniprot id: F4FHR4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

263358:VAB18032 RS00520
gene id: 263358:VAB18032_RS00520
uniprot id: F4FA66
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LamB/PxpA family.
messages: Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
messages: Forms a complex composed of PxpA, PxpB and PxpC.

263358:VAB18032 RS25900
gene id: 263358:VAB18032_RS25900
uniprot id: F4FC72
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

263358:VAB18032 RS26180
gene id: 263358:VAB18032_RS26180
uniprot id: F4FCC8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

263358:VAB18032 RS03470
gene id: 263358:VAB18032_RS03470
uniprot id: F4F166
names: Subcellular Location Annotation
messages: Cell membrane

263358:VAB18032 RS28200
gene id: 263358:VAB18032_RS28200
uniprot id: F4F1X1
names: Function
names: Similarity
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids lysine, threonine, isoleucine and methionine.

263358:VAB18032 RS04410
gene id: 263358:VAB18032_RS04410
uniprot id: F4F4F1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

263358:VAB18032 RS23115
gene id: 263358:VAB18032_RS23115
uniprot id: F4F514
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

263358:VAB18032 RS20305
gene id: 263358:VAB18032_RS20305
uniprot id: F4FDA0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lactate permease family.
messages: Cell membrane
messages: Membrane
messages: Uptake of L-lactate across the membrane. Can also transport D-lactate and glycolate.

263358:VAB18032 RS01525
gene id: 263358:VAB18032_RS01525
uniprot id: F4FCK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Membrane

263358:VAB18032 RS20555
gene id: 263358:VAB18032_RS20555
uniprot id: F4FEB6
names: Similarity
names: Subunit
messages: Belongs to the sigma-70 factor family. ECF subfamily.
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

263358:VAB18032 RS06195
gene id: 263358:VAB18032_RS06195
uniprot id: F4F8A5
names: Subcellular Location Annotation
messages: Membrane

263358:VAB18032 RS17425
gene id: 263358:VAB18032_RS17425
uniprot id: F4F5Y2
names: Similarity
messages: Belongs to the cytochrome P450 family.

263358:VAB18032 RS02395
gene id: 263358:VAB18032_RS02395
uniprot id: F4FEW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

263358:VAB18032 RS06410
gene id: 263358:VAB18032_RS06410
uniprot id: F4F9B5
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

263358:VAB18032 RS17710
gene id: 263358:VAB18032_RS17710
uniprot id: F4F6S4
names: Subcellular Location Annotation
messages: Membrane

263358:VAB18032 RS02060
gene id: 263358:VAB18032_RS02060
uniprot id: F4FEP4
names: Function
names: Similarity
messages: Belongs to the MqnA/MqnD family. MqnD subfamily.
messages: Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2).

263358:VAB18032 RS27565
gene id: 263358:VAB18032_RS27565
uniprot id: F4FGS9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I fumarase family.
messages: Catalyzes the reversible hydration of fumarate to (S)-malate.
messages: Homodimer.

263358:VAB18032 RS22755
gene id: 263358:VAB18032_RS22755
uniprot id: F4F3Y2
names: Similarity
messages: Belongs to the CdaR family.

263358:VAB18032 RS04710
gene id: 263358:VAB18032_RS04710
uniprot id: F4F5D8
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

263358:VAB18032 RS21695
gene id: 263358:VAB18032_RS21695
uniprot id: F4FHP7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

263358:VAB18032 RS14670
gene id: 263358:VAB18032_RS14670
uniprot id: F4FF80
names: Similarity
messages: Belongs to the glycosyl hydrolase 32 family.

263358:VAB18032 RS05120
gene id: 263358:VAB18032_RS05120
uniprot id: F4F6A5
names: Similarity
messages: Belongs to the PGI/PMI family.

263358:VAB18032 RS18740
gene id: 263358:VAB18032_RS18740
uniprot id: F4F8R6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the methyltransferase superfamily. EgtD family.
messages: Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine.
messages: Monomer.

263358:VAB18032 RS13550
gene id: 263358:VAB18032_RS13550
uniprot id: F4FBW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

263358:VAB18032 RS00900
gene id: 263358:VAB18032_RS00900
uniprot id: F4FBA9
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

263358:VAB18032 RS15320
gene id: 263358:VAB18032_RS15320
uniprot id: F4FHE5
names: Similarity
messages: Belongs to the cytochrome P450 family.

263358:VAB18032 RS07115
gene id: 263358:VAB18032_RS07115
uniprot id: F4FBI2
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

263358:VAB18032 RS17785
gene id: 263358:VAB18032_RS17785
uniprot id: F4F6T8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

263358:VAB18032 RS23055
gene id: 263358:VAB18032_RS23055
uniprot id: F4F440
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

263358:VAB18032 RS24040
gene id: 263358:VAB18032_RS24040
uniprot id: F4F713
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

263358:VAB18032 RS29810
gene id: 263358:VAB18032_RS29810
uniprot id: F4FI71
names: Similarity
messages: Belongs to the site-specific recombinase resolvase family.

263358:VAB18032 RS12480
gene id: 263358:VAB18032_RS12480
uniprot id: F4F8J5
names: Similarity
messages: Belongs to the glycosyl hydrolase 53 family.

263358:VAB18032 RS26895
gene id: 263358:VAB18032_RS26895
uniprot id: F4FEK9
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

263358:VAB18032 RS18185
gene id: 263358:VAB18032_RS18185
uniprot id: F4F7Q7
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

263358:VAB18032 RS22705
gene id: 263358:VAB18032_RS22705
uniprot id: F4F307
names: Similarity
messages: Belongs to the UPF0047 family.

263358:VAB18032 RS08150
gene id: 263358:VAB18032_RS08150
uniprot id: F4FDX2
names: Similarity
messages: Belongs to the TPP enzyme family.

263358:VAB18032 RS03960
gene id: 263358:VAB18032_RS03960
uniprot id: F4F396
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

263358:VAB18032 RS17105
gene id: 263358:VAB18032_RS17105
uniprot id: F4F4Y7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpA family.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds the extracellular potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

263358:VAB18032 RS24605
gene id: 263358:VAB18032_RS24605
uniprot id: F4F817
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

263358:VAB18032 RS18525
gene id: 263358:VAB18032_RS18525
uniprot id: F4F8M2
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

263358:VAB18032 RS29510
gene id: 263358:VAB18032_RS29510
uniprot id: F4F5C6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

263358:VAB18032 RS05050
gene id: 263358:VAB18032_RS05050
uniprot id: F4F5K5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

263358:VAB18032 RS19645
gene id: 263358:VAB18032_RS19645
uniprot id: F4FBZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Cdh family.
messages: Membrane

263358:VAB18032 RS25385
gene id: 263358:VAB18032_RS25385
uniprot id: F4FA37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

263358:VAB18032 RS06020
gene id: 263358:VAB18032_RS06020
uniprot id: F4F872
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

263358:VAB18032 RS04775
gene id: 263358:VAB18032_RS04775
uniprot id: F4F5F0
names: Similarity
messages: Belongs to the asparagine synthetase family.

263358:VAB18032 RS20770
gene id: 263358:VAB18032_RS20770
uniprot id: F4FFC4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Cytoplasm
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the insertion of ferrous iron into coproporphyrin III to form Fe-coproporphyrin III.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

263358:VAB18032 RS01665
gene id: 263358:VAB18032_RS01665
uniprot id: F4FDJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

263358:VAB18032 RS16995
gene id: 263358:VAB18032_RS16995
uniprot id: F4F4W6
names: Similarity
messages: Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family.

263358:VAB18032 RS09885
gene id: 263358:VAB18032_RS09885
uniprot id: F4F2C9
names: Subcellular Location Annotation
messages: Cytoplasm

263358:VAB18032 RS10150
gene id: 263358:VAB18032_RS10150
uniprot id: F4F2I2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

263358:VAB18032 RS07000
gene id: 263358:VAB18032_RS07000
uniprot id: F4FAJ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

263358:VAB18032 RS26230
gene id: 263358:VAB18032_RS26230
uniprot id: F4FCD8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

263358:VAB18032 RS26910
gene id: 263358:VAB18032_RS26910
uniprot id: F4FEL2
names: Cofactor
messages: Binds 1 FAD per subunit.

263358:VAB18032 RS18690
gene id: 263358:VAB18032_RS18690
uniprot id: F4F8Q6
names: Similarity
messages: Belongs to the pirin family.

263358:VAB18032 RS27935
gene id: 263358:VAB18032_RS27935
uniprot id: F4FHX1
names: Similarity
messages: Belongs to the EccD/Snm4 family.

263358:VAB18032 RS24735
gene id: 263358:VAB18032_RS24735
uniprot id: F4F8T7
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

263358:VAB18032 RS09220
gene id: 263358:VAB18032_RS09220
uniprot id: F4FH87
names: Similarity
messages: Belongs to the polysaccharide synthase family.

263358:VAB18032 RS07370
gene id: 263358:VAB18032_RS07370
uniprot id: F4FBN3
names: Subcellular Location Annotation
messages: Membrane

263358:VAB18032 RS10585
gene id: 263358:VAB18032_RS10585
uniprot id: F4F3N9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

263358:VAB18032 RS22365
gene id: 263358:VAB18032_RS22365
uniprot id: F4F2U1
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

263358:VAB18032 RS02280
gene id: 263358:VAB18032_RS02280
uniprot id: F4FET8
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

263358:VAB18032 RS25755
gene id: 263358:VAB18032_RS25755
uniprot id: F4FB77
names: Similarity
messages: Belongs to the IMPDH/GMPR family.

263358:VAB18032 RS13350
gene id: 263358:VAB18032_RS13350
uniprot id: F4FBS0
names: Subcellular Location Annotation
messages: Membrane

263358:VAB18032 RS01650
gene id: 263358:VAB18032_RS01650
uniprot id: F4FDJ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

263358:VAB18032 RS17825
gene id: 263358:VAB18032_RS17825
uniprot id: F4F6U6
names: Activity Regulation
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.

263358:VAB18032 RS04485
gene id: 263358:VAB18032_RS04485
uniprot id: F4F4G7
names: Similarity
messages: Belongs to the FBPase class 2 family.

263358:VAB18032 RS24705
gene id: 263358:VAB18032_RS24705
uniprot id: F4F8T2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

263358:VAB18032 RS30080
gene id: 263358:VAB18032_RS30080
uniprot id: F4FBS3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

263358:VAB18032 RS23885
gene id: 263358:VAB18032_RS23885
uniprot id: F4F695
names: Function
names: Similarity
messages: Belongs to the ATP-dependent DNA ligase family.
messages: DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair.

263358:VAB18032 RS28945
gene id: 263358:VAB18032_RS28945
uniprot id: F4F380
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

263358:VAB18032 RS01625
gene id: 263358:VAB18032_RS01625
uniprot id: F4FCM2
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.

263358:VAB18032 RS14545
gene id: 263358:VAB18032_RS14545
uniprot id: F4FF53
names: Similarity
messages: Belongs to the AHA1 family.

263358:VAB18032 RS10170
gene id: 263358:VAB18032_RS10170
uniprot id: F4F2I6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

263358:VAB18032 RS08450
gene id: 263358:VAB18032_RS08450
uniprot id: F4FF02
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

263358:VAB18032 RS22145
gene id: 263358:VAB18032_RS22145
uniprot id: F4F1T2
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

263358:VAB18032 RS14195
gene id: 263358:VAB18032_RS14195
uniprot id: F4FE20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

263358:VAB18032 RS08390
gene id: 263358:VAB18032_RS08390
uniprot id: F4FEZ0
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

263358:VAB18032 RS09950
gene id: 263358:VAB18032_RS09950
uniprot id: F4F2E3
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.

263358:VAB18032 RS04870
gene id: 263358:VAB18032_RS04870
uniprot id: F4F5G9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

263358:VAB18032 RS13005
gene id: 263358:VAB18032_RS13005
uniprot id: F4FAN5
names: Function
messages: TetR is the repressor of the tetracycline resistance element; its N-terminal region forms a helix-turn-helix structure and binds DNA. Binding of tetracycline to TetR reduces the repressor affinity for the tetracycline resistance gene (tetA) promoter operator sites.

263358:VAB18032 RS27130
gene id: 263358:VAB18032_RS27130
uniprot id: F4FFM3
names: Cofactor
names: Domain
names: Function
names: Similarity
messages: Belongs to the nitrobindin family.
messages: Binds 1 heme b group per subunit, that coordinates a highly solvent-exposed Fe(III) atom.
messages: Forms a 10-stranded antiparallel beta-barrel structure able to accommodate a hydrophobic ligand in its interior. In fact, this fold hosts the heme group, which is located in a wide surface cleft.
messages: Heme-binding protein able to scavenge peroxynitrite and to protect free L-tyrosine against peroxynitrite-mediated nitration, by acting as a peroxynitrite isomerase that converts peroxynitrite to nitrate. Therefore, this protein likely plays a role in peroxynitrite sensing and in the detoxification of reactive nitrogen and oxygen species (RNS and ROS, respectively). Is able to bind nitric oxide (NO) in vitro, but may act as a sensor of peroxynitrite levels in vivo.

263358:VAB18032 RS07025
gene id: 263358:VAB18032_RS07025
uniprot id: F4FAJ9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

263358:VAB18032 RS26825
gene id: 263358:VAB18032_RS26825
uniprot id: F4FEJ4
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

263358:VAB18032 RS00005
gene id: 263358:VAB18032_RS00005
uniprot id: F4F835
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

263358:VAB18032 RS13655
gene id: 263358:VAB18032_RS13655
uniprot id: F4FBY1
names: Subcellular Location Annotation
messages: Membrane

263358:VAB18032 RS21110
gene id: 263358:VAB18032_RS21110
uniprot id: F4FFJ5
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

263358:VAB18032 RS13435
gene id: 263358:VAB18032_RS13435
uniprot id: F4FBT7
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

263358:VAB18032 RS26285
gene id: 263358:VAB18032_RS26285
uniprot id: F4FDB7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

263358:VAB18032 RS19510
gene id: 263358:VAB18032_RS19510
uniprot id: F4FB04
names: Subcellular Location Annotation
messages: Membrane

263358:VAB18032 RS04245
gene id: 263358:VAB18032_RS04245
uniprot id: F4F3F3
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

263358:VAB18032 RS04540
gene id: 263358:VAB18032_RS04540
uniprot id: F4F4H9
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

263358:VAB18032 RS21850
gene id: 263358:VAB18032_RS21850
uniprot id: F4FHS8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

263358:VAB18032 RS05005
gene id: 263358:VAB18032_RS05005
uniprot id: F4F5J6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

263358:VAB18032 RS24700
gene id: 263358:VAB18032_RS24700
uniprot id: F4F8T1
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

263358:VAB18032 RS12375
gene id: 263358:VAB18032_RS12375
uniprot id: F4F8H5
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

263358:VAB18032 RS17760
gene id: 263358:VAB18032_RS17760
uniprot id: F4F6T4
names: Cofactor
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
messages: Binds 2 nickel ions per subunit.
messages: Carbamylation allows a single lysine to coordinate two nickel ions.
messages: Carboxylation allows a single lysine to coordinate two nickel ions.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

263358:VAB18032 RS07155
gene id: 263358:VAB18032_RS07155
uniprot id: F4FBJ0
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

263358:VAB18032 RS26075
gene id: 263358:VAB18032_RS26075
uniprot id: F4FCA7
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

263358:VAB18032 RS14355
gene id: 263358:VAB18032_RS14355
uniprot id: F4FE51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

263358:VAB18032 RS27905
gene id: 263358:VAB18032_RS27905
uniprot id: F4FHW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

263358:VAB18032 RS18595
gene id: 263358:VAB18032_RS18595
uniprot id: F4F8N7
names: Similarity
messages: Belongs to the OsmC/Ohr family.

263358:VAB18032 RS14405
gene id: 263358:VAB18032_RS14405
uniprot id: F4FE61
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 2 residues (Tyr-69 and Arg-72) present in a large hydrophobic pocket are probably involved in substrate specificity. They are important for desuccinylation activity, but dispensable for deacetylation activity.
messages: Belongs to the sirtuin family. Class III subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form.

263358:VAB18032 RS20605
gene id: 263358:VAB18032_RS20605
uniprot id: F4FEC6
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

263358:VAB18032 RS15950
gene id: 263358:VAB18032_RS15950
uniprot id: F4F1L4
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

263358:VAB18032 RS29385
gene id: 263358:VAB18032_RS29385
uniprot id: F4F5A0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 87 family.
messages: Membrane

263358:VAB18032 RS07380
gene id: 263358:VAB18032_RS07380
uniprot id: F4FBN5
names: Subcellular Location Annotation
messages: Membrane

263358:VAB18032 RS29915
gene id: 263358:VAB18032_RS29915
uniprot id: F4F5F3
names: Similarity
messages: Belongs to the peptidase S8 family.

263358:VAB18032 RS21735
gene id: 263358:VAB18032_RS21735
uniprot id: F4FHQ5
names: Similarity
messages: Belongs to the UPF0235 family.

263358:VAB18032 RS24895
gene id: 263358:VAB18032_RS24895
uniprot id: F4F8W9
names: Similarity
messages: Belongs to the CutA family.

263358:VAB18032 RS09630
gene id: 263358:VAB18032_RS09630
uniprot id: F4F1B1
names: Subcellular Location Annotation
messages: Membrane

263358:VAB18032 RS14410
gene id: 263358:VAB18032_RS14410
uniprot id: F4FE62
names: Similarity
messages: Belongs to the prokaryotic/mitochondrial release factor family.

263358:VAB18032 RS05500
gene id: 263358:VAB18032_RS05500
uniprot id: F4F770
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AB hydrolase superfamily.
messages: Periplasm

263358:VAB18032 RS00335
gene id: 263358:VAB18032_RS00335
uniprot id: F4F962
names: Subcellular Location Annotation
messages: Membrane

263358:VAB18032 RS03320
gene id: 263358:VAB18032_RS03320
uniprot id: F4F136
names: Similarity
messages: Belongs to the arginase family.

263358:VAB18032 RS02265
gene id: 263358:VAB18032_RS02265
uniprot id: F4FET5
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

263358:VAB18032 RS21145
gene id: 263358:VAB18032_RS21145
uniprot id: F4FGG9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gluconeogenesis factor family.
messages: Cytoplasm
messages: Required for morphogenesis under gluconeogenic growth conditions.

263358:VAB18032 RS18825
gene id: 263358:VAB18032_RS18825
uniprot id: F4F9Q0
names: Similarity
messages: Belongs to the asparagine synthetase family.

263358:VAB18032 RS24035
gene id: 263358:VAB18032_RS24035
uniprot id: F4F712
names: Similarity
messages: Belongs to the YciI family.

263358:VAB18032 RS23570
gene id: 263358:VAB18032_RS23570
uniprot id: F4F635
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

263358:VAB18032 RS21665
gene id: 263358:VAB18032_RS21665
uniprot id: F4FHP0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

263358:VAB18032 RS14105
gene id: 263358:VAB18032_RS14105
uniprot id: F4FE02
names: Similarity
messages: Belongs to the threonine aldolase family.

263358:VAB18032 RS04300
gene id: 263358:VAB18032_RS04300
uniprot id: F4F4D0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

263358:VAB18032 RS03720
gene id: 263358:VAB18032_RS03720
uniprot id: F4F284
names: Similarity
messages: Belongs to the UDPGP type 2 family.

263358:VAB18032 RS12885
gene id: 263358:VAB18032_RS12885
uniprot id: F4F9P4
names: Subcellular Location Annotation
messages: Cytoplasm

263358:VAB18032 RS00540
gene id: 263358:VAB18032_RS00540
uniprot id: F4FA71
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

263358:VAB18032 RS26070
gene id: 263358:VAB18032_RS26070
uniprot id: F4FCA6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

263358:VAB18032 RS24870
gene id: 263358:VAB18032_RS24870
uniprot id: F4F8W4
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

263358:VAB18032 RS12085
gene id: 263358:VAB18032_RS12085
uniprot id: F4F7L8
names: Similarity
messages: Belongs to the AHA1 family.

263358:VAB18032 RS21225
gene id: 263358:VAB18032_RS21225
uniprot id: F4FGI6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

263358:VAB18032 RS21335
gene id: 263358:VAB18032_RS21335
uniprot id: F4FGK9
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.

263358:VAB18032 RS14610
gene id: 263358:VAB18032_RS14610
uniprot id: F4FF68
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

263358:VAB18032 RS01965
gene id: 263358:VAB18032_RS01965
uniprot id: F4FDQ6
names: Similarity
messages: Belongs to the peptidase C56 family.

263358:VAB18032 RS11920
gene id: 263358:VAB18032_RS11920
uniprot id: F4F7I5
names: Subcellular Location Annotation
messages: Membrane

263358:VAB18032 RS19310
gene id: 263358:VAB18032_RS19310
uniprot id: F4FAW2
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

263358:VAB18032 RS20755
gene id: 263358:VAB18032_RS20755
uniprot id: F4FFC1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

263358:VAB18032 RS10430
gene id: 263358:VAB18032_RS10430
uniprot id: F4F3K7
names: Similarity
messages: Belongs to the OMP decarboxylase family. Type 2 subfamily.

263358:VAB18032 RS22190
gene id: 263358:VAB18032_RS22190
uniprot id: F4F1U1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Rieske iron-sulfur protein family.
messages: Cell membrane
messages: Iron-sulfur subunit of the cytochrome bc1 complex, an essential component of the respiratory electron transport chain required for ATP synthesis. The bc1 complex catalyzes the oxidation of menaquinol and the reduction of cytochrome c in the respiratory chain. The bc1 complex operates through a Q-cycle mechanism that couples electron transfer to generation of the proton gradient that drives ATP synthesis.
messages: Membrane

263358:VAB18032 RS20025
gene id: 263358:VAB18032_RS20025
uniprot id: F4FD42
names: Similarity
messages: Belongs to the iron/ascorbate-dependent oxidoreductase family.

263358:VAB18032 RS23105
gene id: 263358:VAB18032_RS23105
uniprot id: F4F448
names: Subcellular Location Annotation
messages: Membrane

263358:VAB18032 RS23475
gene id: 263358:VAB18032_RS23475
uniprot id: F4F586
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

263358:VAB18032 RS18550
gene id: 263358:VAB18032_RS18550
uniprot id: F4F8M7
names: Similarity
messages: Belongs to the citrate synthase family.

263358:VAB18032 RS15090
gene id: 263358:VAB18032_RS15090
uniprot id: F4FGD3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

263358:VAB18032 RS07375
gene id: 263358:VAB18032_RS07375
uniprot id: F4FBN4
names: Similarity
messages: Belongs to the F420H(2)-dependent quinone reductase family.

263358:VAB18032 RS12920
gene id: 263358:VAB18032_RS12920
uniprot id: F4FAL4
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

263358:VAB18032 RS21135
gene id: 263358:VAB18032_RS21135
uniprot id: F4FGG7
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

263358:VAB18032 RS18775
gene id: 263358:VAB18032_RS18775
uniprot id: F4F8S3
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

263358:VAB18032 RS09290
gene id: 263358:VAB18032_RS09290
uniprot id: F4FHA1
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

263358:VAB18032 RS09450
gene id: 263358:VAB18032_RS09450
uniprot id: F4F175
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

263358:VAB18032 RS25435
gene id: 263358:VAB18032_RS25435
uniprot id: F4FA47
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

263358:VAB18032 RS18665
gene id: 263358:VAB18032_RS18665
uniprot id: F4F8Q1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

263358:VAB18032 RS22160
gene id: 263358:VAB18032_RS22160
uniprot id: F4F1T5
names: Similarity
messages: Belongs to the RelA/SpoT family.

263358:VAB18032 RS17295
gene id: 263358:VAB18032_RS17295
uniprot id: F4F5V6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0324 family.
messages: Membrane

263358:VAB18032 RS03840
gene id: 263358:VAB18032_RS03840
uniprot id: F4F2A7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

263358:VAB18032 RS21970
gene id: 263358:VAB18032_RS21970
uniprot id: F4F1P6
names: Similarity
messages: Belongs to the threonine aldolase family.

263358:VAB18032 RS18005
gene id: 263358:VAB18032_RS18005
uniprot id: F4F6Y4
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

263358:VAB18032 RS07640
gene id: 263358:VAB18032_RS07640
uniprot id: F4FCQ6
names: Subcellular Location Annotation
messages: Membrane

263358:VAB18032 RS10005
gene id: 263358:VAB18032_RS10005
uniprot id: F4F2F4
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

263358:VAB18032 RS17090
gene id: 263358:VAB18032_RS17090
uniprot id: F4F4Y5
names: Similarity
messages: Belongs to the peptidase S51 family.

263358:VAB18032 RS06610
gene id: 263358:VAB18032_RS06610
uniprot id: F4F9F5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

263358:VAB18032 RS19125
gene id: 263358:VAB18032_RS19125
uniprot id: F4F9W1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

263358:VAB18032 RS26005
gene id: 263358:VAB18032_RS26005
uniprot id: F4FC93
names: Function
messages: Catalyzes the phosphorylation of hydroxymethylpyrimidine phosphate (HMP-P) to HMP-PP, and of HMP to HMP-P.

263358:VAB18032 RS01605
gene id: 263358:VAB18032_RS01605
uniprot id: F4FCL8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

263358:VAB18032 RS23310
gene id: 263358:VAB18032_RS23310
uniprot id: F4F553
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

263358:VAB18032 RS29015
gene id: 263358:VAB18032_RS29015
uniprot id: F4F461
names: Similarity
messages: Belongs to the FPG family.

263358:VAB18032 RS27335
gene id: 263358:VAB18032_RS27335
uniprot id: F4FFR7
names: Function
names: Similarity
messages: Belongs to the threonine synthase family.
messages: Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.

263358:VAB18032 RS26220
gene id: 263358:VAB18032_RS26220
uniprot id: F4FCD6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

263358:VAB18032 RS05755
gene id: 263358:VAB18032_RS05755
uniprot id: F4F7C4
names: Similarity
messages: Belongs to the glycosyl hydrolase 12 (cellulase H) family.

263358:VAB18032 RS21745
gene id: 263358:VAB18032_RS21745
uniprot id: F4FHQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DivIVA family.
messages: Cytoplasm

263358:VAB18032 RS09175
gene id: 263358:VAB18032_RS09175
uniprot id: F4FH78
names: Similarity
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.

263358:VAB18032 RS04780
gene id: 263358:VAB18032_RS04780
uniprot id: F4F5F1
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

263358:VAB18032 RS03635
gene id: 263358:VAB18032_RS03635
uniprot id: F4F265
names: Similarity
messages: Belongs to the thioredoxin family.

263358:VAB18032 RS19375
gene id: 263358:VAB18032_RS19375
uniprot id: F4FAX6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

263358:VAB18032 RS04550
gene id: 263358:VAB18032_RS04550
uniprot id: F4F4I1
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

263358:VAB18032 RS18215
gene id: 263358:VAB18032_RS18215
uniprot id: F4F7R3
names: Cofactor
messages: Binds 2 manganese ions per subunit.

263358:VAB18032 RS06795
gene id: 263358:VAB18032_RS06795
uniprot id: F4FAF6
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

263358:VAB18032 RS10575
gene id: 263358:VAB18032_RS10575
uniprot id: F4F3N7
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

263358:VAB18032 RS22235
gene id: 263358:VAB18032_RS22235
uniprot id: F4F1V0
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.

263358:VAB18032 RS09800
gene id: 263358:VAB18032_RS09800
uniprot id: F4F1E7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

263358:VAB18032 RS28070
gene id: 263358:VAB18032_RS28070
uniprot id: F4FHZ9
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

263358:VAB18032 RS03745
gene id: 263358:VAB18032_RS03745
uniprot id: F4F288
names: Subcellular Location Annotation
messages: Membrane

263358:VAB18032 RS06965
gene id: 263358:VAB18032_RS06965
uniprot id: F4FAI7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

263358:VAB18032 RS24425
gene id: 263358:VAB18032_RS24425
uniprot id: F4F7Y0
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

263358:VAB18032 RS27450
gene id: 263358:VAB18032_RS27450
uniprot id: F4FGQ7
names: Subcellular Location Annotation
messages: Membrane

263358:VAB18032 RS13370
gene id: 263358:VAB18032_RS13370
uniprot id: F4FBS4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell inner membrane
messages: Membrane

263358:VAB18032 RS22330
gene id: 263358:VAB18032_RS22330
uniprot id: F4F2T4
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

263358:VAB18032 RS21425
gene id: 263358:VAB18032_RS21425
uniprot id: F4FGM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

263358:VAB18032 RS23735
gene id: 263358:VAB18032_RS23735
uniprot id: F4F665
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the 3-HAO family.
messages: Binds 2 Fe(2+) ions per subunit.
messages: Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate.

263358:VAB18032 RS20765
gene id: 263358:VAB18032_RS20765
uniprot id: F4FFC3
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

263358:VAB18032 RS07185
gene id: 263358:VAB18032_RS07185
uniprot id: F4FBJ6
names: Subcellular Location Annotation
messages: Membrane

263358:VAB18032 RS04200
gene id: 263358:VAB18032_RS04200
uniprot id: F4F3E4
names: Similarity
messages: Belongs to the phosphohexose mutase family.

263358:VAB18032 RS19740
gene id: 263358:VAB18032_RS19740
uniprot id: F4FC15
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

263358:VAB18032 RS26185
gene id: 263358:VAB18032_RS26185
uniprot id: F4FCC9
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

263358:VAB18032 RS27630
gene id: 263358:VAB18032_RS27630
uniprot id: F4FGU2
names: Similarity
messages: Belongs to the homogentisate dioxygenase family.

263358:VAB18032 RS24265
gene id: 263358:VAB18032_RS24265
uniprot id: F4F759
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

263358:VAB18032 RS17995
gene id: 263358:VAB18032_RS17995
uniprot id: F4F6Y2
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.

263358:VAB18032 RS18910
gene id: 263358:VAB18032_RS18910
uniprot id: F4F9R7
names: Similarity
messages: Belongs to the peptidase S8 family.

263358:VAB18032 RS02095
gene id: 263358:VAB18032_RS02095
uniprot id: F4FEQ1
names: Subcellular Location Annotation
messages: Membrane

263358:VAB18032 RS00875
gene id: 263358:VAB18032_RS00875
uniprot id: F4FBA4
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

263358:VAB18032 RS15490
gene id: 263358:VAB18032_RS15490
uniprot id: F4FHI0
names: Function
messages: Acyltransferase required for the direct transfer of medium- to long-chain fatty acyl moieties from a carrier protein (MbtL) on to the epsilon-amino group of lysine residue in the mycobactin core.

263358:VAB18032 RS06930
gene id: 263358:VAB18032_RS06930
uniprot id: F4FAI0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

263358:VAB18032 RS05950
gene id: 263358:VAB18032_RS05950
uniprot id: F4F859
names: Subcellular Location Annotation
messages: Membrane

263358:VAB18032 RS16125
gene id: 263358:VAB18032_RS16125
uniprot id: F4F2L3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SelA family.
messages: Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.
messages: Cytoplasm

263358:VAB18032 RS07820
gene id: 263358:VAB18032_RS07820
uniprot id: F4FCU3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

263358:VAB18032 RS23695
gene id: 263358:VAB18032_RS23695
uniprot id: F4F657
names: Similarity
messages: Belongs to the LacAB/RpiB family.

263358:VAB18032 RS21055
gene id: 263358:VAB18032_RS21055
uniprot id: F4FFI4
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

263358:VAB18032 RS06830
gene id: 263358:VAB18032_RS06830
uniprot id: F4FAG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

263358:VAB18032 RS12740
gene id: 263358:VAB18032_RS12740
uniprot id: F4F9L5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

263358:VAB18032 RS04195
gene id: 263358:VAB18032_RS04195
uniprot id: F4F3E3
names: Subcellular Location Annotation
messages: Membrane

263358:VAB18032 RS04505
gene id: 263358:VAB18032_RS04505
uniprot id: F4F4H1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

263358:VAB18032 RS06550
gene id: 263358:VAB18032_RS06550
uniprot id: F4F9E3
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

263358:VAB18032 RS03355
gene id: 263358:VAB18032_RS03355
uniprot id: F4F144
names: Subcellular Location Annotation
messages: Membrane

263358:VAB18032 RS06835
gene id: 263358:VAB18032_RS06835
uniprot id: F4FAG2
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

263358:VAB18032 RS14325
gene id: 263358:VAB18032_RS14325
uniprot id: F4FE45
names: Similarity
messages: Belongs to the glycosyl hydrolase 10 (cellulase F) family.

263358:VAB18032 RS16220
gene id: 263358:VAB18032_RS16220
uniprot id: F4F2N2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

263358:VAB18032 RS13105
gene id: 263358:VAB18032_RS13105
uniprot id: F4FAQ5
names: Similarity
messages: Belongs to the TPP enzyme family.

263358:VAB18032 RS26150
gene id: 263358:VAB18032_RS26150
uniprot id: F4FCC2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

263358:VAB18032 RS26160
gene id: 263358:VAB18032_RS26160
uniprot id: F4FCC4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

263358:VAB18032 RS22990
gene id: 263358:VAB18032_RS22990
uniprot id: F4F430
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

263358:VAB18032 RS03780
gene id: 263358:VAB18032_RS03780
uniprot id: F4F295
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

263358:VAB18032 RS21610
gene id: 263358:VAB18032_RS21610
uniprot id: F4FHN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

263358:VAB18032 RS14685
gene id: 263358:VAB18032_RS14685
uniprot id: F4FF83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

263358:VAB18032 RS05780
gene id: 263358:VAB18032_RS05780
uniprot id: F4F7C9
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

263358:VAB18032 RS27225
gene id: 263358:VAB18032_RS27225
uniprot id: F4FFP3
names: Similarity
messages: Belongs to the PhoU family.
messages: Belongs to the UPF0111 family.

263358:VAB18032 RS29040
gene id: 263358:VAB18032_RS29040
uniprot id: F4F466
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

263358:VAB18032 RS00585
gene id: 263358:VAB18032_RS00585
uniprot id: F4FA81
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

263358:VAB18032 RS24530
gene id: 263358:VAB18032_RS24530
uniprot id: F4F802
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

263358:VAB18032 RS24210
gene id: 263358:VAB18032_RS24210
uniprot id: F4F747
names: Similarity
messages: Belongs to the peptidase C40 family.

263358:VAB18032 RS01770
gene id: 263358:VAB18032_RS01770
uniprot id: F4FDL5
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

263358:VAB18032 RS01610
gene id: 263358:VAB18032_RS01610
uniprot id: F4FCL9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

263358:VAB18032 RS14770
gene id: 263358:VAB18032_RS14770
uniprot id: F4FFA1
names: Subcellular Location Annotation
messages: Membrane

263358:VAB18032 RS29515
gene id: 263358:VAB18032_RS29515
uniprot id: F4F5C7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

263358:VAB18032 RS02660
gene id: 263358:VAB18032_RS02660
uniprot id: F4FFX8
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

263358:VAB18032 RS07560
gene id: 263358:VAB18032_RS07560
uniprot id: F4FCP0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
messages: Cytoplasm

263358:VAB18032 RS07410
gene id: 263358:VAB18032_RS07410
uniprot id: F4FBP1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

263358:VAB18032 RS20255
gene id: 263358:VAB18032_RS20255
uniprot id: F4FD90
names: Subcellular Location Annotation
messages: Membrane

263358:VAB18032 RS03315
gene id: 263358:VAB18032_RS03315
uniprot id: F4F135
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Catalyzes the reversible hydration of carbon dioxide to form bicarbonate.

263358:VAB18032 RS07765
gene id: 263358:VAB18032_RS07765
uniprot id: F4FCT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

263358:VAB18032 RS07135
gene id: 263358:VAB18032_RS07135
uniprot id: F4FBI6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

263358:VAB18032 RS01505
gene id: 263358:VAB18032_RS01505
uniprot id: F4FCJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

263358:VAB18032 RS23770
gene id: 263358:VAB18032_RS23770
uniprot id: F4F672
names: Function
names: Similarity
messages: Belongs to the aromatic-ring hydroxylase family. KMO subfamily.
messages: Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid.

263358:VAB18032 RS21000
gene id: 263358:VAB18032_RS21000
uniprot id: F4FFH3
names: Subcellular Location Annotation
messages: Membrane

263358:VAB18032 RS25290
gene id: 263358:VAB18032_RS25290
uniprot id: F4FA17
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

263358:VAB18032 RS15565
gene id: 263358:VAB18032_RS15565
uniprot id: F4FHJ5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

263358:VAB18032 RS14045
gene id: 263358:VAB18032_RS14045
uniprot id: F4FD27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Membrane

263358:VAB18032 RS17445
gene id: 263358:VAB18032_RS17445
uniprot id: F4F5Y6
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

263358:VAB18032 RS27595
gene id: 263358:VAB18032_RS27595
uniprot id: F4FGT5
names: Subcellular Location Annotation
messages: Membrane

263358:VAB18032 RS04305
gene id: 263358:VAB18032_RS04305
uniprot id: F4F4D1
names: Subcellular Location Annotation
messages: Membrane

263358:VAB18032 RS22765
gene id: 263358:VAB18032_RS22765
uniprot id: F4F3Y4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

263358:VAB18032 RS10280
gene id: 263358:VAB18032_RS10280
uniprot id: F4F3H4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

263358:VAB18032 RS16435
gene id: 263358:VAB18032_RS16435
uniprot id: F4F2S5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

263358:VAB18032 RS01645
gene id: 263358:VAB18032_RS01645
uniprot id: F4FDJ0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

263358:VAB18032 RS31245
gene id: 263358:VAB18032_RS31245
uniprot id: F4FBS7
names: Similarity
messages: Belongs to the cytochrome P450 family.

263358:VAB18032 RS26235
gene id: 263358:VAB18032_RS26235
uniprot id: F4FCD9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

263358:VAB18032 RS08190
gene id: 263358:VAB18032_RS08190
uniprot id: F4FDY0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protoporphyrinogen/coproporphyrinogen oxidase family. Coproporphyrinogen III oxidase subfamily.
messages: Cytoplasm
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the oxidation of coproporphyrinogen III to coproporphyrin III.

263358:VAB18032 RS10805
gene id: 263358:VAB18032_RS10805
uniprot id: F4F4P6
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

263358:VAB18032 RS28260
gene id: 263358:VAB18032_RS28260
uniprot id: F4F1Y3
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

263358:VAB18032 RS08350
gene id: 263358:VAB18032_RS08350
uniprot id: F4FEY2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

263358:VAB18032 RS01020
gene id: 263358:VAB18032_RS01020
uniprot id: F4FBD0
names: Similarity
messages: Belongs to the peptidase C40 family.

263358:VAB18032 RS23070
gene id: 263358:VAB18032_RS23070
uniprot id: F4F443
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily.

263358:VAB18032 RS26095
gene id: 263358:VAB18032_RS26095
uniprot id: F4FCB1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

263358:VAB18032 RS09130
gene id: 263358:VAB18032_RS09130
uniprot id: F4FH69
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

263358:VAB18032 RS15230
gene id: 263358:VAB18032_RS15230
uniprot id: F4FGG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

263358:VAB18032 RS08170
gene id: 263358:VAB18032_RS08170
uniprot id: F4FDX6
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

263358:VAB18032 RS11590
gene id: 263358:VAB18032_RS11590
uniprot id: F4F6M9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

263358:VAB18032 RS06445
gene id: 263358:VAB18032_RS06445
uniprot id: F4F9C2
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

263358:VAB18032 RS23855
gene id: 263358:VAB18032_RS23855
uniprot id: F4F689
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

263358:VAB18032 RS23325
gene id: 263358:VAB18032_RS23325
uniprot id: F4F556
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

263358:VAB18032 RS20135
gene id: 263358:VAB18032_RS20135
uniprot id: F4FD66
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

263358:VAB18032 RS27840
gene id: 263358:VAB18032_RS27840
uniprot id: F4FHV1
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

263358:VAB18032 RS21350
gene id: 263358:VAB18032_RS21350
uniprot id: F4FGL2
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

263358:VAB18032 RS16470
gene id: 263358:VAB18032_RS16470
uniprot id: F4F3P6
names: Similarity
names: Subunit
messages: Belongs to the sigma-70 factor family. ECF subfamily.
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

263358:VAB18032 RS24775
gene id: 263358:VAB18032_RS24775
uniprot id: F4F8U5
names: Subcellular Location Annotation
messages: Membrane

263358:VAB18032 RS05405
gene id: 263358:VAB18032_RS05405
uniprot id: F4F6G2
names: Similarity
messages: Belongs to the YciI family.

263358:VAB18032 RS04315
gene id: 263358:VAB18032_RS04315
uniprot id: F4F4D3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

263358:VAB18032 RS17435
gene id: 263358:VAB18032_RS17435
uniprot id: F4F5Y4
names: Similarity
messages: Belongs to the thioesterase family.

263358:VAB18032 RS20410
gene id: 263358:VAB18032_RS20410
uniprot id: F4FE85
names: Subcellular Location Annotation
messages: Membrane

263358:VAB18032 RS14120
gene id: 263358:VAB18032_RS14120
uniprot id: F4FE05
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

263358:VAB18032 RS25680
gene id: 263358:VAB18032_RS25680
uniprot id: F4FB62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

263358:VAB18032 RS25810
gene id: 263358:VAB18032_RS25810
uniprot id: F4FB88
names: Subcellular Location Annotation
messages: Membrane

263358:VAB18032 RS26175
gene id: 263358:VAB18032_RS26175
uniprot id: F4FCC7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

263358:VAB18032 RS13050
gene id: 263358:VAB18032_RS13050
uniprot id: F4FAP4
names: Similarity
messages: Belongs to the 4-hydroxy-2-oxovalerate aldolase family.

263358:VAB18032 RS07835
gene id: 263358:VAB18032_RS07835
uniprot id: F4FCU6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

263358:VAB18032 RS05565
gene id: 263358:VAB18032_RS05565
uniprot id: F4F785
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

263358:VAB18032 RS20720
gene id: 263358:VAB18032_RS20720
uniprot id: F4FEF0
names: Similarity
messages: Belongs to the band 7/mec-2 family.

263358:VAB18032 RS21090
gene id: 263358:VAB18032_RS21090
uniprot id: F4FFJ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 2 subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

263358:VAB18032 RS21445
gene id: 263358:VAB18032_RS21445
uniprot id: F4FGN0
names: Similarity
messages: Belongs to the YciI family.

263358:VAB18032 RS10885
gene id: 263358:VAB18032_RS10885
uniprot id: F4F4R2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

263358:VAB18032 RS04155
gene id: 263358:VAB18032_RS04155
uniprot id: F4F3D5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

263358:VAB18032 RS03725
gene id: 263358:VAB18032_RS03725
uniprot id: F4F285
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

263358:VAB18032 RS09745
gene id: 263358:VAB18032_RS09745
uniprot id: F4F1D6
names: Subcellular Location Annotation
messages: Membrane

263358:VAB18032 RS03940
gene id: 263358:VAB18032_RS03940
uniprot id: F4F393
names: Subcellular Location Annotation
messages: Membrane

263358:VAB18032 RS04620
gene id: 263358:VAB18032_RS04620
uniprot id: F4F4J5
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

263358:VAB18032 RS19890
gene id: 263358:VAB18032_RS19890
uniprot id: F4FC46
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

263358:VAB18032 RS02120
gene id: 263358:VAB18032_RS02120
uniprot id: F4FEQ6
names: Similarity
messages: Belongs to the citrate synthase family.

263358:VAB18032 RS04415
gene id: 263358:VAB18032_RS04415
uniprot id: F4F4F2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

263358:VAB18032 RS13080
gene id: 263358:VAB18032_RS13080
uniprot id: F4FAQ0
names: Similarity
messages: Belongs to the bacterial microcompartments protein family.

263358:VAB18032 RS22500
gene id: 263358:VAB18032_RS22500
uniprot id: F4F2W8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

263358:VAB18032 RS23840
gene id: 263358:VAB18032_RS23840
uniprot id: F4F686
names: Similarity
messages: Belongs to the glycosyltransferase 20 family.

263358:VAB18032 RS03510
gene id: 263358:VAB18032_RS03510
uniprot id: F4F174
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

263358:VAB18032 RS05835
gene id: 263358:VAB18032_RS05835
uniprot id: F4F7E0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAL/histidase family.
messages: Cytoplasm

263358:VAB18032 RS04845
gene id: 263358:VAB18032_RS04845
uniprot id: F4F5G4
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

263358:VAB18032 RS00505
gene id: 263358:VAB18032_RS00505
uniprot id: F4FA63
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0073 (Hly-III) family.
messages: Membrane

263358:VAB18032 RS03760
gene id: 263358:VAB18032_RS03760
uniprot id: F4F291
names: Similarity
messages: Belongs to the YciI family.

263358:VAB18032 RS08950
gene id: 263358:VAB18032_RS08950
uniprot id: F4FG67
names: Similarity
messages: Belongs to the CsoR family.

263358:VAB18032 RS14175
gene id: 263358:VAB18032_RS14175
uniprot id: F4FE16
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

263358:VAB18032 RS11745
gene id: 263358:VAB18032_RS11745
uniprot id: F4F7F0
names: Subcellular Location Annotation
messages: Membrane

263358:VAB18032 RS22345
gene id: 263358:VAB18032_RS22345
uniprot id: F4F2T7
names: Similarity
messages: Belongs to the GcvT family.

263358:VAB18032 RS07845
gene id: 263358:VAB18032_RS07845
uniprot id: F4FCU8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

263358:VAB18032 RS12635
gene id: 263358:VAB18032_RS12635
uniprot id: F4F9J4
names: Subcellular Location Annotation
messages: Membrane

263358:VAB18032 RS18050
gene id: 263358:VAB18032_RS18050
uniprot id: F4F7N0
names: Domain
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic ubiquitin-like protein family.
messages: Is modified by deamidation of its C-terminal glutamine to glutamate by the deamidase Dop, a prerequisite to the subsequent pupylation process.
messages: Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation.
messages: Strongly interacts with the proteasome-associated ATPase ARC through a hydrophobic interface; the interacting region of Pup lies in its C-terminal half. There is one Pup binding site per ARC hexamer ring.
messages: The N-terminal unstructured half of Pup provides a signal required to initiate unfolding and degradation by the proteasome but is not needed for pupylation, while the C-terminal helical half of Pup interacts with ARC to target proteins to the proteasome.