2604832:FXN65 RS03005
gene id: 2604832:FXN65_RS03005
uniprot id: A0A5J6QE94
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

2604832:FXN65 RS23285
gene id: 2604832:FXN65_RS23285
uniprot id: A0A5J6QSY2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

2604832:FXN65 RS27135
gene id: 2604832:FXN65_RS27135
uniprot id: A0A5J6QT08
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

2604832:FXN65 RS12425
gene id: 2604832:FXN65_RS12425
uniprot id: A0A5J6QTM0
names: Function
names: Similarity
messages: Belongs to the PqqA family.
messages: Required for coenzyme pyrroloquinoline quinone (PQQ) biosynthesis. PQQ is probably formed by cross-linking a specific glutamate to a specific tyrosine residue and excising these residues from the peptide.

2604832:FXN65 RS01870
gene id: 2604832:FXN65_RS01870
uniprot id: A0A5J6QEW3
names: Function
messages: Repressor involved in choline regulation of the bet genes.
messages: Repressor involved in the biosynthesis of the osmoprotectant glycine betaine. It represses transcription of the choline transporter BetT and the genes of BetAB involved in the synthesis of glycine betaine.

2604832:FXN65 RS02995
gene id: 2604832:FXN65_RS02995
uniprot id: A0A5J6QJR0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

2604832:FXN65 RS27140
gene id: 2604832:FXN65_RS27140
uniprot id: A0A5J6QS46
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

2604832:FXN65 RS10095
gene id: 2604832:FXN65_RS10095
uniprot id: A0A5J6QJ27
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

2604832:FXN65 RS26820
gene id: 2604832:FXN65_RS26820
uniprot id: A0A5J6QV01
names: Similarity
messages: Belongs to the thioredoxin family.

2604832:FXN65 RS10060
gene id: 2604832:FXN65_RS10060
uniprot id: A0A5J6QNI5
names: Cofactor
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cell inner membrane
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD.
messages: The heme is bound between the two transmembrane subunits.

2604832:FXN65 RS05235
gene id: 2604832:FXN65_RS05235
uniprot id: A0A5J6QGK5
names: Subcellular Location Annotation
messages: Cytoplasm

2604832:FXN65 RS02940
gene id: 2604832:FXN65_RS02940
uniprot id: A0A5J6QGL5
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

2604832:FXN65 RS13360
gene id: 2604832:FXN65_RS13360
uniprot id: A0A5J6QKB3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 4-oxalocrotonate tautomerase family.
messages: Catalyzes the ketonization of 2-hydroxymuconate stereoselectively to yield 2-oxo-3-hexenedioate.
messages: Homohexamer.

2604832:FXN65 RS19700
gene id: 2604832:FXN65_RS19700
uniprot id: A0A5J6QNT8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

2604832:FXN65 RS14440
gene id: 2604832:FXN65_RS14440
uniprot id: A0A5J6QLA1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 4-oxalocrotonate tautomerase family.
messages: Catalyzes the ketonization of 2-hydroxymuconate stereoselectively to yield 2-oxo-3-hexenedioate.
messages: Homohexamer.

2604832:FXN65 RS22020
gene id: 2604832:FXN65_RS22020
uniprot id: A0A5J6QPZ1
names: Subcellular Location Annotation
messages: Cytoplasm

2604832:FXN65 RS23490
gene id: 2604832:FXN65_RS23490
uniprot id: A0A5J6QQ92
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2604832:FXN65 RS02895
gene id: 2604832:FXN65_RS02895
uniprot id: A0A5J6QJP0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

2604832:FXN65 RS03035
gene id: 2604832:FXN65_RS03035
uniprot id: A0A5J6QEP1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

2604832:FXN65 RS27285
gene id: 2604832:FXN65_RS27285
uniprot id: A0A5J6QT40
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.

2604832:FXN65 RS02950
gene id: 2604832:FXN65_RS02950
uniprot id: A0A5J6QF14
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

2604832:FXN65 RS18010
gene id: 2604832:FXN65_RS18010
uniprot id: A0A5J6QQL9
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.

2604832:FXN65 RS02990
gene id: 2604832:FXN65_RS02990
uniprot id: A0A5J6QGM7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

2604832:FXN65 RS15130
gene id: 2604832:FXN65_RS15130
uniprot id: A0A5J6QNN6
names: Similarity
messages: Belongs to the UDPGP type 2 family.

2604832:FXN65 RS02960
gene id: 2604832:FXN65_RS02960
uniprot id: A0A5J6QKH6
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

2604832:FXN65 RS23745
gene id: 2604832:FXN65_RS23745
uniprot id: A0A5J6QW35
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

2604832:FXN65 RS17765
gene id: 2604832:FXN65_RS17765
uniprot id: A0A5J6QNF4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

2604832:FXN65 RS26295
gene id: 2604832:FXN65_RS26295
uniprot id: A0A5J6QSJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

2604832:FXN65 RS25315
gene id: 2604832:FXN65_RS25315
uniprot id: A0A5J6QWI4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

2604832:FXN65 RS26280
gene id: 2604832:FXN65_RS26280
uniprot id: A0A5J6QSJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

2604832:FXN65 RS02860
gene id: 2604832:FXN65_RS02860
uniprot id: A0A5J6QKF5
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

2604832:FXN65 RS27190
gene id: 2604832:FXN65_RS27190
uniprot id: A0A5J6QS57
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

2604832:FXN65 RS27750
gene id: 2604832:FXN65_RS27750
uniprot id: A0A5J6QXS7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

2604832:FXN65 RS25380
gene id: 2604832:FXN65_RS25380
uniprot id: A0A5J6QWI9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

2604832:FXN65 RS25840
gene id: 2604832:FXN65_RS25840
uniprot id: A0A5J6QVF1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

2604832:FXN65 RS04245
gene id: 2604832:FXN65_RS04245
uniprot id: A0A5J6QEY1
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

2604832:FXN65 RS02930
gene id: 2604832:FXN65_RS02930
uniprot id: A0A5J6QFC7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

2604832:FXN65 RS00945
gene id: 2604832:FXN65_RS00945
uniprot id: A0A5J6QHK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

2604832:FXN65 RS21405
gene id: 2604832:FXN65_RS21405
uniprot id: A0A5J6QPT7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Pal lipoprotein family.
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

2604832:FXN65 RS23865
gene id: 2604832:FXN65_RS23865
uniprot id: A0A5J6QR41
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

2604832:FXN65 RS02955
gene id: 2604832:FXN65_RS02955
uniprot id: A0A5J6QE83
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

2604832:FXN65 RS03050
gene id: 2604832:FXN65_RS03050
uniprot id: A0A5J6QF31
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

2604832:FXN65 RS23595
gene id: 2604832:FXN65_RS23595
uniprot id: A0A5J6QW07
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DksA family.
messages: Cytoplasm
messages: Interacts directly with the RNA polymerase.
messages: Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression.

2604832:FXN65 RS18610
gene id: 2604832:FXN65_RS18610
uniprot id: A0A5J6QQX3
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

2604832:FXN65 RS02945
gene id: 2604832:FXN65_RS02945
uniprot id: A0A5J6QJQ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

2604832:FXN65 RS17760
gene id: 2604832:FXN65_RS17760
uniprot id: A0A5J6QSR5
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

2604832:FXN65 RS02935
gene id: 2604832:FXN65_RS02935
uniprot id: A0A5J6QEM1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

2604832:FXN65 RS22695
gene id: 2604832:FXN65_RS22695
uniprot id: A0A5J6QTT8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

2604832:FXN65 RS02880
gene id: 2604832:FXN65_RS02880
uniprot id: A0A5J6QFC0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

2604832:FXN65 RS01590
gene id: 2604832:FXN65_RS01590
uniprot id: A0A5J6QDI9
names: Function
names: Similarity
messages: Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
messages: Belongs to the Nudix hydrolase family. RppH subfamily.

2604832:FXN65 RS25860
gene id: 2604832:FXN65_RS25860
uniprot id: A0A5J6QUH0
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

2604832:FXN65 RS04905
gene id: 2604832:FXN65_RS04905
uniprot id: A0A5J6QFU5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

2604832:FXN65 RS04220
gene id: 2604832:FXN65_RS04220
uniprot id: A0A5J6QG20
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

2604832:FXN65 RS27030
gene id: 2604832:FXN65_RS27030
uniprot id: A0A5J6QXC8
names: Similarity
messages: Belongs to the P(II) protein family.

2604832:FXN65 RS18020
gene id: 2604832:FXN65_RS18020
uniprot id: A0A5J6QNK8
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

2604832:FXN65 RS06750
gene id: 2604832:FXN65_RS06750
uniprot id: A0A5J6QGV6
names: Similarity
names: Subunit
messages: Belongs to the muconolactone Delta-isomerase family.
messages: Homodecamer.

2604832:FXN65 RS15610
gene id: 2604832:FXN65_RS15610
uniprot id: A0A5J6QPU6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

2604832:FXN65 RS02975
gene id: 2604832:FXN65_RS02975
uniprot id: A0A5J6QHN3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

2604832:FXN65 RS02540
gene id: 2604832:FXN65_RS02540
uniprot id: A0A5J6QJI0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

2604832:FXN65 RS17745
gene id: 2604832:FXN65_RS17745
uniprot id: A0A5J6QMY2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

2604832:FXN65 RS03025
gene id: 2604832:FXN65_RS03025
uniprot id: A0A5J6QHP3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

2604832:FXN65 RS18700
gene id: 2604832:FXN65_RS18700
uniprot id: A0A5J6QRJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfur carrier protein TusA family.
messages: Cytoplasm
messages: Sulfur carrier protein which probably makes part of a sulfur-relay system.

2604832:FXN65 RS09360
gene id: 2604832:FXN65_RS09360
uniprot id: A0A5J6QN54
names: Subcellular Location Annotation
messages: Membrane

2604832:FXN65 RS21935
gene id: 2604832:FXN65_RS21935
uniprot id: A0A5J6QQ44
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2604832:FXN65 RS22365
gene id: 2604832:FXN65_RS22365
uniprot id: A0A5J6QQM1
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

2604832:FXN65 RS23720
gene id: 2604832:FXN65_RS23720
uniprot id: A0A5J6QR07
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

2604832:FXN65 RS03000
gene id: 2604832:FXN65_RS03000
uniprot id: A0A5J6QF23
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

2604832:FXN65 RS02915
gene id: 2604832:FXN65_RS02915
uniprot id: A0A5J6QES9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

2604832:FXN65 RS03030
gene id: 2604832:FXN65_RS03030
uniprot id: A0A5J6QFE7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

2604832:FXN65 RS03045
gene id: 2604832:FXN65_RS03045
uniprot id: A0A5J6QJR9
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

2604832:FXN65 RS01310
gene id: 2604832:FXN65_RS01310
uniprot id: A0A5J6QDH7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division. Important for assembly or stability of the septal ring.

2604832:FXN65 RS18630
gene id: 2604832:FXN65_RS18630
uniprot id: A0A5J6QTC1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

2604832:FXN65 RS03460
gene id: 2604832:FXN65_RS03460
uniprot id: A0A5J6QFC4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

2604832:FXN65 RS02875
gene id: 2604832:FXN65_RS02875
uniprot id: A0A5J6QHL4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

2604832:FXN65 RS02970
gene id: 2604832:FXN65_RS02970
uniprot id: A0A5J6QIN5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

2604832:FXN65 RS04910
gene id: 2604832:FXN65_RS04910
uniprot id: A0A5J6QJI9
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

2604832:FXN65 RS17180
gene id: 2604832:FXN65_RS17180
uniprot id: A0A5J6QN49
names: Cofactor
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.

2604832:FXN65 RS27810
gene id: 2604832:FXN65_RS27810
uniprot id: A0A5J6QSK6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

2604832:FXN65 RS02965
gene id: 2604832:FXN65_RS02965
uniprot id: A0A5J6QEU4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

2604832:FXN65 RS27755
gene id: 2604832:FXN65_RS27755
uniprot id: A0A5J6QTC9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

2604832:FXN65 RS02440
gene id: 2604832:FXN65_RS02440
uniprot id: A0A5J6QEJ6
names: Similarity
messages: Belongs to the UPF0057 (PMP3) family.

2604832:FXN65 RS20645
gene id: 2604832:FXN65_RS20645
uniprot id: A0A5J6QPF6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small RNA(s).
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

2604832:FXN65 RS07320
gene id: 2604832:FXN65_RS07320
uniprot id: A0A5J6QMS2
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

2604832:FXN65 RS15705
gene id: 2604832:FXN65_RS15705
uniprot id: A0A5J6QRV4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell membrane
messages: NDH-1 is composed of 13 different subunits. Subunits NuoB, CD, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

2604832:FXN65 RS27320
gene id: 2604832:FXN65_RS27320
uniprot id: A0A5J6QT50
names: Function
messages: This protein is a positive regulator for the phosphate regulon. Transcription of this operon is positively regulated by PhoB and PhoR when phosphate is limited.