259536:PSYC RS08365
gene id: 259536:PSYC_RS08365
uniprot id: Q4FR98
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

259536:PSYC RS04135
gene id: 259536:PSYC_RS04135
uniprot id: Q4FTL2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

259536:PSYC RS05685
gene id: 259536:PSYC_RS05685
uniprot id: Q4FSR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Membrane

259536:PSYC RS06715
gene id: 259536:PSYC_RS06715
uniprot id: Q4FS63
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

259536:PSYC RS08330
gene id: 259536:PSYC_RS08330
uniprot id: Q4FRA3
names: Subcellular Location Annotation
messages: Membrane

259536:PSYC RS00390
gene id: 259536:PSYC_RS00390
uniprot id: Q4FVL0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

259536:PSYC RS00830
gene id: 259536:PSYC_RS00830
uniprot id: Q4FVC1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

259536:PSYC RS01540
gene id: 259536:PSYC_RS01540
uniprot id: Q4FUZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane

259536:PSYC RS03635
gene id: 259536:PSYC_RS03635
uniprot id: Q4FTV3
names: Similarity
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Belongs to the peroxiredoxin family. Prx6 subfamily.

259536:PSYC RS09235
gene id: 259536:PSYC_RS09235
uniprot id: Q4FQS7
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

259536:PSYC RS01420
gene id: 259536:PSYC_RS01420
uniprot id: Q4FV14
names: Similarity
messages: Belongs to the UPF0178 family.

259536:PSYC RS08630
gene id: 259536:PSYC_RS08630
uniprot id: Q4FR47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

259536:PSYC RS01580
gene id: 259536:PSYC_RS01580
uniprot id: Q4FUY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

259536:PSYC RS08375
gene id: 259536:PSYC_RS08375
uniprot id: Q4FR96
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

259536:PSYC RS04820
gene id: 259536:PSYC_RS04820
uniprot id: Q4FT78
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

259536:PSYC RS06635
gene id: 259536:PSYC_RS06635
uniprot id: Q4FS79
names: Subcellular Location Annotation
messages: Membrane

259536:PSYC RS09725
gene id: 259536:PSYC_RS09725
uniprot id: Q4FQI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial secretin family.
messages: Cell outer membrane
messages: Membrane

259536:PSYC RS09170
gene id: 259536:PSYC_RS09170
uniprot id: Q4FQT9
names: Function
names: Similarity
names: Subunit
messages: Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division.
messages: Belongs to the ZapA family. Type 1 subfamily.
messages: Homodimer. Interacts with FtsZ.

259536:PSYC RS06580
gene id: 259536:PSYC_RS06580
uniprot id: Q4FS90
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.

259536:PSYC RS00570
gene id: 259536:PSYC_RS00570
uniprot id: Q4FVH3
names: Similarity
messages: Belongs to the phosphohexose mutase family.

259536:PSYC RS03550
gene id: 259536:PSYC_RS03550
uniprot id: Q4FTX0
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.

259536:PSYC RS04790
gene id: 259536:PSYC_RS04790
uniprot id: Q4FT84
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

259536:PSYC RS10790
gene id: 259536:PSYC_RS10790
uniprot id: Q4FPX9
names: Subcellular Location Annotation
messages: Membrane

259536:PSYC RS01410
gene id: 259536:PSYC_RS01410
uniprot id: Q4FV16
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. PdxB subfamily.
messages: Catalyzes the oxidation of erythronate-4-phosphate to 3-hydroxy-2-oxo-4-phosphonooxybutanoate.
messages: Cytoplasm
messages: Homodimer.

259536:PSYC RS01005
gene id: 259536:PSYC_RS01005
uniprot id: Q4FV90
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

259536:PSYC RS09935
gene id: 259536:PSYC_RS09935
uniprot id: Q4FQE0
names: Similarity
messages: Belongs to the LOG family.

259536:PSYC RS06060
gene id: 259536:PSYC_RS06060
uniprot id: Q4FSJ3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of sn-l,2-diacylglycerol (DAG) to phosphatidic acid. Involved in the recycling of diacylglycerol produced as a by-product during membrane-derived oligosaccharide (MDO) biosynthesis.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

259536:PSYC RS00970
gene id: 259536:PSYC_RS00970
uniprot id: Q4FV98
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: In the N-terminal section; belongs to the FGAMS family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.

259536:PSYC RS05800
gene id: 259536:PSYC_RS05800
uniprot id: Q4FSP2
names: Similarity
messages: Belongs to the PrpF family.

259536:PSYC RS10970
gene id: 259536:PSYC_RS10970
uniprot id: Q4FPV3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

259536:PSYC RS01145
gene id: 259536:PSYC_RS01145
uniprot id: Q4FV63
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

259536:PSYC RS03830
gene id: 259536:PSYC_RS03830
uniprot id: Q4FTS1
names: Similarity
messages: Belongs to the RecJ family.

259536:PSYC RS04965
gene id: 259536:PSYC_RS04965
uniprot id: Q4FT49
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose 5-phosphate isomerase family.
messages: Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
messages: Homodimer.

259536:PSYC RS07825
gene id: 259536:PSYC_RS07825
uniprot id: Q4FRJ9
names: Subcellular Location Annotation
messages: Membrane

259536:PSYC RS00225
gene id: 259536:PSYC_RS00225
uniprot id: Q4FVP1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

259536:PSYC RS06710
gene id: 259536:PSYC_RS06710
uniprot id: Q4FS64
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

259536:PSYC RS09815
gene id: 259536:PSYC_RS09815
uniprot id: Q4FQG4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

259536:PSYC RS01115
gene id: 259536:PSYC_RS01115
uniprot id: Q4FV69
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LysR transcriptional regulatory family.
messages: Cytoplasm

259536:PSYC RS08590
gene id: 259536:PSYC_RS08590
uniprot id: Q4FR54
names: Similarity
messages: Belongs to the MipA/OmpV family.

259536:PSYC RS08125
gene id: 259536:PSYC_RS08125
uniprot id: Q4FRE2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.

259536:PSYC RS06835
gene id: 259536:PSYC_RS06835
uniprot id: Q4FS40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

259536:PSYC RS04975
gene id: 259536:PSYC_RS04975
uniprot id: Q4FT47
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

259536:PSYC RS09830
gene id: 259536:PSYC_RS09830
uniprot id: Q4FQG1
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

259536:PSYC RS09145
gene id: 259536:PSYC_RS09145
uniprot id: Q4FQU4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

259536:PSYC RS05005
gene id: 259536:PSYC_RS05005
uniprot id: Q4FT41
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

259536:PSYC RS01510
gene id: 259536:PSYC_RS01510
uniprot id: Q4FUZ7
names: Similarity
messages: Belongs to the barstar family.

259536:PSYC RS05615
gene id: 259536:PSYC_RS05615
uniprot id: Q4FSS9
names: Function
names: Similarity
messages: Belongs to the bacterioferritin family.
messages: Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex.

259536:PSYC RS02595
gene id: 259536:PSYC_RS02595
uniprot id: Q4FUE9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

259536:PSYC RS02040
gene id: 259536:PSYC_RS02040
uniprot id: Q4FUQ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

259536:PSYC RS00180
gene id: 259536:PSYC_RS00180
uniprot id: Q4FVQ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsbB family.
messages: Cell inner membrane
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein.

259536:PSYC RS07990
gene id: 259536:PSYC_RS07990
uniprot id: Q4FRG7
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

259536:PSYC RS00815
gene id: 259536:PSYC_RS00815
uniprot id: Q4FVC4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

259536:PSYC RS06100
gene id: 259536:PSYC_RS06100
uniprot id: Q4FSI5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

259536:PSYC RS01960
gene id: 259536:PSYC_RS01960
uniprot id: Q4FUR0
names: Similarity
messages: Belongs to the OsmC/Ohr family.

259536:PSYC RS07310
gene id: 259536:PSYC_RS07310
uniprot id: Q4FRV0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

259536:PSYC RS07470
gene id: 259536:PSYC_RS07470
uniprot id: Q4FRR8
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

259536:PSYC RS08150
gene id: 259536:PSYC_RS08150
uniprot id: Q4FRD7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

259536:PSYC RS10825
gene id: 259536:PSYC_RS10825
uniprot id: Q4FPX2
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetyltransferase family. ArgA subfamily.
messages: Cytoplasm
messages: In bacteria which possess the bifunctional enzyme ornithine acetyltransferase/N-acetylglutamate synthase (ArgJ), ArgA fulfills an anaplerotic role.

259536:PSYC RS01315
gene id: 259536:PSYC_RS01315
uniprot id: Q4FV35
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

259536:PSYC RS07930
gene id: 259536:PSYC_RS07930
uniprot id: Q4FRH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

259536:PSYC RS06085
gene id: 259536:PSYC_RS06085
uniprot id: Q4FSI8
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

259536:PSYC RS09790
gene id: 259536:PSYC_RS09790
uniprot id: Q4FQG8
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

259536:PSYC RS03565
gene id: 259536:PSYC_RS03565
uniprot id: Q4FTW7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

259536:PSYC RS07205
gene id: 259536:PSYC_RS07205
uniprot id: Q4FRX0
names: Similarity
messages: Belongs to the DSD1 family.

259536:PSYC RS06305
gene id: 259536:PSYC_RS06305
uniprot id: Q4FSE5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

259536:PSYC RS09880
gene id: 259536:PSYC_RS09880
uniprot id: Q4FQF1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

259536:PSYC RS08995
gene id: 259536:PSYC_RS08995
uniprot id: Q4FQX3
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

259536:PSYC RS06310
gene id: 259536:PSYC_RS06310
uniprot id: Q4FSE4
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

259536:PSYC RS02885
gene id: 259536:PSYC_RS02885
uniprot id: Q4FU93
names: Similarity
messages: Belongs to the UPF0246 family.

259536:PSYC RS08665
gene id: 259536:PSYC_RS08665
uniprot id: Q4FR39
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.

259536:PSYC RS07000
gene id: 259536:PSYC_RS07000
uniprot id: Q4FS10
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

259536:PSYC RS00595
gene id: 259536:PSYC_RS00595
uniprot id: Q4FVG8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

259536:PSYC RS03360
gene id: 259536:PSYC_RS03360
uniprot id: Q4FU08
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gtrA family.
messages: Involved in O antigen modification. Involved in the translocation of bactoprenol-linked glucose across the cytoplasmic membrane.
messages: Membrane

259536:PSYC RS00520
gene id: 259536:PSYC_RS00520
uniprot id: Q4FVI3
names: Cofactor
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.

259536:PSYC RS10200
gene id: 259536:PSYC_RS10200
uniprot id: Q4FQ93
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

259536:PSYC RS08440
gene id: 259536:PSYC_RS08440
uniprot id: Q4FR83
names: Cofactor
messages: Can also use Mn(2+) ion.

259536:PSYC RS05595
gene id: 259536:PSYC_RS05595
uniprot id: Q4FST3
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

259536:PSYC RS06870
gene id: 259536:PSYC_RS06870
uniprot id: Q4FS33
names: Subcellular Location Annotation
messages: Membrane

259536:PSYC RS08790
gene id: 259536:PSYC_RS08790
uniprot id: Q4FR14
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruD family.
messages: Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.

259536:PSYC RS08160
gene id: 259536:PSYC_RS08160
uniprot id: Q4FRD5
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

259536:PSYC RS08495
gene id: 259536:PSYC_RS08495
uniprot id: Q4FR73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

259536:PSYC RS10320
gene id: 259536:PSYC_RS10320
uniprot id: Q4FQ69
names: Subcellular Location Annotation
messages: Membrane

259536:PSYC RS01675
gene id: 259536:PSYC_RS01675
uniprot id: Q4FUW5
names: Cofactor
names: Similarity
messages: Belongs to the UPF0313 family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

259536:PSYC RS06440
gene id: 259536:PSYC_RS06440
uniprot id: Q4FSB8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

259536:PSYC RS02755
gene id: 259536:PSYC_RS02755
uniprot id: Q4FUB7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

259536:PSYC RS04740
gene id: 259536:PSYC_RS04740
uniprot id: Q4FT94
names: Function
names: Similarity
messages: Belongs to the LpxB family.
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

259536:PSYC RS08070
gene id: 259536:PSYC_RS08070
uniprot id: Q4FRF3
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

259536:PSYC RS04240
gene id: 259536:PSYC_RS04240
uniprot id: Q4FTJ2
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

259536:PSYC RS04585
gene id: 259536:PSYC_RS04585
uniprot id: Q4FTC4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HsdR family.
messages: Subunit R is required for both nuclease and ATPase activities, but not for modification.
messages: The type I restriction/modification system is composed of three polypeptides R, M and S.

259536:PSYC RS04075
gene id: 259536:PSYC_RS04075
uniprot id: Q4FTM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

259536:PSYC RS09445
gene id: 259536:PSYC_RS09445
uniprot id: Q4FQN5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmE/CycJ family.
messages: Cell inner membrane
messages: Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.

259536:PSYC RS03310
gene id: 259536:PSYC_RS03310
uniprot id: Q4FU18
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate.
messages: Cytoplasm

259536:PSYC RS02160
gene id: 259536:PSYC_RS02160
uniprot id: Q4FUM7
names: Similarity
messages: Belongs to the GST superfamily.

259536:PSYC RS10575
gene id: 259536:PSYC_RS10575
uniprot id: Q4FQ18
names: Similarity
messages: Belongs to the P(II) protein family.

259536:PSYC RS05890
gene id: 259536:PSYC_RS05890
uniprot id: Q4FSM5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

259536:PSYC RS07695
gene id: 259536:PSYC_RS07695
uniprot id: Q4FRM6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

259536:PSYC RS07245
gene id: 259536:PSYC_RS07245
uniprot id: Q4FRW2
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

259536:PSYC RS10685
gene id: 259536:PSYC_RS10685
uniprot id: Q4FQ00
names: Function
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.

259536:PSYC RS07440
gene id: 259536:PSYC_RS07440
uniprot id: Q4FRS4
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

259536:PSYC RS07800
gene id: 259536:PSYC_RS07800
uniprot id: Q4FRK5
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

259536:PSYC RS06195
gene id: 259536:PSYC_RS06195
uniprot id: Q4FSG7
names: Cofactor
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Binds 1 Fe(3+) ion per subunit.

259536:PSYC RS03280
gene id: 259536:PSYC_RS03280
uniprot id: Q4FU24
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Cell inner membrane
messages: Homoheptamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.
messages: Membrane

259536:PSYC RS10450
gene id: 259536:PSYC_RS10450
uniprot id: Q4FQ43
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein S19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein S19.

259536:PSYC RS09540
gene id: 259536:PSYC_RS09540
uniprot id: Q4FQL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

259536:PSYC RS10025
gene id: 259536:PSYC_RS10025
uniprot id: Q4FQC2
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

259536:PSYC RS06355
gene id: 259536:PSYC_RS06355
uniprot id: Q4FSD5
names: Similarity
messages: Belongs to the EcnA/EcnB lipoprotein family.

259536:PSYC RS04285
gene id: 259536:PSYC_RS04285
uniprot id: Q4FTI3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

259536:PSYC RS08575
gene id: 259536:PSYC_RS08575
uniprot id: Q4FR57
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lactate permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Uptake of L-lactate across the membrane. Can also transport D-lactate and glycolate.

259536:PSYC RS08970
gene id: 259536:PSYC_RS08970
uniprot id: Q4FQX8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

259536:PSYC RS06220
gene id: 259536:PSYC_RS06220
uniprot id: Q4FSG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

259536:PSYC RS01940
gene id: 259536:PSYC_RS01940
uniprot id: Q4FUR4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MetX family.
messages: Cytoplasm
messages: Homodimer.
messages: Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine.

259536:PSYC RS06915
gene id: 259536:PSYC_RS06915
uniprot id: Q4FS24
names: Function
names: Similarity
messages: Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PSRP subfamily.
messages: Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation.

259536:PSYC RS10490
gene id: 259536:PSYC_RS10490
uniprot id: Q4FQ35
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

259536:PSYC RS03235
gene id: 259536:PSYC_RS03235
uniprot id: Q4FU31
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

259536:PSYC RS01250
gene id: 259536:PSYC_RS01250
uniprot id: Q4FV47
names: Similarity
messages: Belongs to the N-Me-Phe pilin family.

259536:PSYC RS10920
gene id: 259536:PSYC_RS10920
uniprot id: Q4FPW3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also edits incorrectly charged L-seryl-tRNA(Thr).
messages: Cytoplasm
messages: Homodimer.

259536:PSYC RS09080
gene id: 259536:PSYC_RS09080
uniprot id: Q4FQV7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.

259536:PSYC RS07325
gene id: 259536:PSYC_RS07325
uniprot id: Q4FRU7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

259536:PSYC RS06015
gene id: 259536:PSYC_RS06015
uniprot id: Q4FSK2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
messages: Catalyzes the reversible phosphorylation of S-methyl-5'-thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.
messages: Homohexamer. Dimer of a homotrimer.

259536:PSYC RS09975
gene id: 259536:PSYC_RS09975
uniprot id: Q4FQD2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Membrane

259536:PSYC RS07250
gene id: 259536:PSYC_RS07250
uniprot id: Q4FRW1
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.

259536:PSYC RS05015
gene id: 259536:PSYC_RS05015
uniprot id: Q4FT39
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

259536:PSYC RS10750
gene id: 259536:PSYC_RS10750
uniprot id: Q4FPY7
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

259536:PSYC RS02860
gene id: 259536:PSYC_RS02860
uniprot id: Q4FU98
names: Similarity
messages: Belongs to the WrbA family.

259536:PSYC RS00995
gene id: 259536:PSYC_RS00995
uniprot id: Q4FV92
names: Similarity
messages: Belongs to the UPF0053 family.

259536:PSYC RS04500
gene id: 259536:PSYC_RS04500
uniprot id: Q4FTE1
names: Similarity
messages: Belongs to the transposase 8 family.

259536:PSYC RS06235
gene id: 259536:PSYC_RS06235
uniprot id: Q4FSF9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e. capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

259536:PSYC RS01365
gene id: 259536:PSYC_RS01365
uniprot id: Q4FV25
names: Similarity
messages: Belongs to the UPF0125 (RnfH) family.

259536:PSYC RS05860
gene id: 259536:PSYC_RS05860
uniprot id: Q4FSN0
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA.
messages: Belongs to the helicase family. UvrD subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding. Interacts with RecA.
messages: The C-terminal domain has nuclease activity and interacts with RecD. It interacts with RecA, facilitating its loading onto ssDNA.
messages: The N-terminal DNA-binding domain is a ssDNA-dependent ATPase and has ATP-dependent 3'-5' helicase function. This domain interacts with RecC.

259536:PSYC RS08175
gene id: 259536:PSYC_RS08175
uniprot id: Q4FRD2
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

259536:PSYC RS06430
gene id: 259536:PSYC_RS06430
uniprot id: Q4FSC0
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

259536:PSYC RS09360
gene id: 259536:PSYC_RS09360
uniprot id: Q4FQQ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MinC family.
messages: Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization.
messages: Interacts with MinD and FtsZ.

259536:PSYC RS08765
gene id: 259536:PSYC_RS08765
uniprot id: Q4FR19
names: Similarity
messages: Belongs to the ThrE exporter (TC 2.A.79) family.

259536:PSYC RS00155
gene id: 259536:PSYC_RS00155
uniprot id: Q4FVQ5
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

259536:PSYC RS07615
gene id: 259536:PSYC_RS07615
uniprot id: Q4FRP2
names: Function
names: Similarity
messages: Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.

259536:PSYC RS08115
gene id: 259536:PSYC_RS08115
uniprot id: Q4FRE4
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

259536:PSYC RS00550
gene id: 259536:PSYC_RS00550
uniprot id: Q4FVH7
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

259536:PSYC RS10485
gene id: 259536:PSYC_RS10485
uniprot id: Q4FQ36
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

259536:PSYC RS00325
gene id: 259536:PSYC_RS00325
uniprot id: Q4FVM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell inner membrane
messages: Membrane

259536:PSYC RS10030
gene id: 259536:PSYC_RS10030
uniprot id: Q4FQC1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

259536:PSYC RS03250
gene id: 259536:PSYC_RS03250
uniprot id: Q4FU28
names: Subcellular Location Annotation
messages: Membrane

259536:PSYC RS04690
gene id: 259536:PSYC_RS04690
uniprot id: Q4FTA4
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

259536:PSYC RS07390
gene id: 259536:PSYC_RS07390
uniprot id: Q4FRT4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

259536:PSYC RS09810
gene id: 259536:PSYC_RS09810
uniprot id: Q4FQG5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

259536:PSYC RS10530
gene id: 259536:PSYC_RS10530
uniprot id: Q4FQ27
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Zinc importer (TC 3.A.1.15.5) family.
messages: Cell inner membrane
messages: Part of the ABC transporter complex ZnuABC involved in zinc import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (ZnuC), two transmembrane proteins (ZnuB) and a solute-binding protein (ZnuA).

259536:PSYC RS04025
gene id: 259536:PSYC_RS04025
uniprot id: Q4FTN4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).

259536:PSYC RS00840
gene id: 259536:PSYC_RS00840
uniprot id: Q4FVB9
names: Similarity
messages: Belongs to the YggT family.

259536:PSYC RS02080
gene id: 259536:PSYC_RS02080
uniprot id: Q4FUP0
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

259536:PSYC RS02615
gene id: 259536:PSYC_RS02615
uniprot id: Q4FUE5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

259536:PSYC RS07710
gene id: 259536:PSYC_RS07710
uniprot id: Q4FRM3
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

259536:PSYC RS11100
gene id: 259536:PSYC_RS11100
uniprot id: Q4FPS8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

259536:PSYC RS08490
gene id: 259536:PSYC_RS08490
uniprot id: Q4FR74
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

259536:PSYC RS00125
gene id: 259536:PSYC_RS00125
uniprot id: Q4FVR1
names: Similarity
messages: Belongs to the IMPACT family.

259536:PSYC RS01050
gene id: 259536:PSYC_RS01050
uniprot id: Q4FV82
names: Function
names: Similarity
messages: Belongs to the sigma-54 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

259536:PSYC RS08585
gene id: 259536:PSYC_RS08585
uniprot id: Q4FR55
names: Subcellular Location Annotation
messages: Membrane

259536:PSYC RS02580
gene id: 259536:PSYC_RS02580
uniprot id: Q4FUF2
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

259536:PSYC RS01755
gene id: 259536:PSYC_RS01755
uniprot id: Q4FUV0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

259536:PSYC RS00545
gene id: 259536:PSYC_RS00545
uniprot id: Q4FVH8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

259536:PSYC RS08595
gene id: 259536:PSYC_RS08595
uniprot id: Q4FR53
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

259536:PSYC RS11095
gene id: 259536:PSYC_RS11095
uniprot id: Q4FPS9
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

259536:PSYC RS03850
gene id: 259536:PSYC_RS03850
uniprot id: Q4FTR7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family.
messages: Cytoplasm
messages: Homotrimer.

259536:PSYC RS09765
gene id: 259536:PSYC_RS09765
uniprot id: Q4FQH3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

259536:PSYC RS10580
gene id: 259536:PSYC_RS10580
uniprot id: Q4FQ17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Membrane

259536:PSYC RS07625
gene id: 259536:PSYC_RS07625
uniprot id: Q4FRP0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

259536:PSYC RS08710
gene id: 259536:PSYC_RS08710
uniprot id: Q4FR30
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome. Modification of Lys-34 is required for alleviation.
messages: May be beta-lysylated on the epsilon-amino group of Lys-34 by the combined action of EpmA and EpmB, and then hydroxylated on the C5 position of the same residue by EpmC (if this protein is present). Lysylation is critical for the stimulatory effect of EF-P on peptide-bond formation. The lysylation moiety may extend toward the peptidyltransferase center and stabilize the terminal 3-CCA end of the tRNA. Hydroxylation of the C5 position on Lys-34 may allow additional potential stabilizing hydrogen-bond interactions with the P-tRNA.

259536:PSYC RS08905
gene id: 259536:PSYC_RS08905
uniprot id: Q4FQZ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 90 family.
messages: Cytoplasm
messages: Homodimer.
messages: Molecular chaperone. Has ATPase activity.

259536:PSYC RS09365
gene id: 259536:PSYC_RS09365
uniprot id: Q4FQQ1
names: Function
names: Similarity
names: Subunit
messages: ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.
messages: Belongs to the ParA family. MinD subfamily.
messages: Interacts with MinC and FtsZ.

259536:PSYC RS11155
gene id: 259536:PSYC_RS11155
uniprot id: Q4FPR7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell inner membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

259536:PSYC RS09295
gene id: 259536:PSYC_RS09295
uniprot id: Q4FQR5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.
messages: Serves to protect the cell against DNA damage by alkyl hydroperoxides. It can use either NADH or NADPH as electron donor for direct reduction of redox dyes or of alkyl hydroperoxides when combined with the AhpC protein.

259536:PSYC RS10420
gene id: 259536:PSYC_RS10420
uniprot id: Q4FQ49
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

259536:PSYC RS06605
gene id: 259536:PSYC_RS06605
uniprot id: Q4FS85
names: Similarity
messages: Belongs to the transglycosylase Slt family.

259536:PSYC RS05620
gene id: 259536:PSYC_RS05620
uniprot id: Q4FSS8
names: Function
names: Similarity
messages: Belongs to the bacterioferritin family.
messages: Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex.

259536:PSYC RS03520
gene id: 259536:PSYC_RS03520
uniprot id: Q4FTX6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

259536:PSYC RS01485
gene id: 259536:PSYC_RS01485
uniprot id: Q4FV02
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

259536:PSYC RS09970
gene id: 259536:PSYC_RS09970
uniprot id: Q4FQD3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

259536:PSYC RS09560
gene id: 259536:PSYC_RS09560
uniprot id: Q4FQL3
names: Subcellular Location Annotation
messages: Cell inner membrane

259536:PSYC RS07235
gene id: 259536:PSYC_RS07235
uniprot id: Q4FRW4
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. S-2-haloalkanoic acid dehalogenase family.

259536:PSYC RS02990
gene id: 259536:PSYC_RS02990
uniprot id: Q4FU77
names: Function
names: Similarity
messages: Belongs to the catalase family. HPII subfamily.
messages: Serves to protect cells from the toxic effects of hydrogen peroxide.

259536:PSYC RS06165
gene id: 259536:PSYC_RS06165
uniprot id: Q4FSH3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

259536:PSYC RS05450
gene id: 259536:PSYC_RS05450
uniprot id: Q4FSW2
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

259536:PSYC RS00280
gene id: 259536:PSYC_RS00280
uniprot id: Q4FVN0
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

259536:PSYC RS03590
gene id: 259536:PSYC_RS03590
uniprot id: Q4FTW2
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

259536:PSYC RS10930
gene id: 259536:PSYC_RS10930
uniprot id: Q4FPW1
names: Similarity
messages: Belongs to the TelA family.

259536:PSYC RS00535
gene id: 259536:PSYC_RS00535
uniprot id: Q4FVI0
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

259536:PSYC RS02775
gene id: 259536:PSYC_RS02775
uniprot id: Q4FUB3
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

259536:PSYC RS00340
gene id: 259536:PSYC_RS00340
uniprot id: Q4FVL8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

259536:PSYC RS01155
gene id: 259536:PSYC_RS01155
uniprot id: Q4FV61
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

259536:PSYC RS02585
gene id: 259536:PSYC_RS02585
uniprot id: Q4FUF1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity).

259536:PSYC RS01680
gene id: 259536:PSYC_RS01680
uniprot id: Q4FUW4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

259536:PSYC RS02025
gene id: 259536:PSYC_RS02025
uniprot id: Q4FUQ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L/F-transferase family.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.

259536:PSYC RS08285
gene id: 259536:PSYC_RS08285
uniprot id: Q4FRB1
names: Subcellular Location Annotation
messages: Membrane

259536:PSYC RS07895
gene id: 259536:PSYC_RS07895
uniprot id: Q4FRI5
names: Subcellular Location Annotation
messages: Membrane

259536:PSYC RS02180
gene id: 259536:PSYC_RS02180
uniprot id: Q4FUM4
names: Similarity
messages: Belongs to the thiolase-like superfamily. Chalcone/stilbene synthases family.

259536:PSYC RS08885
gene id: 259536:PSYC_RS08885
uniprot id: Q4FQZ5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

259536:PSYC RS08015
gene id: 259536:PSYC_RS08015
uniprot id: Q4FRG2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

259536:PSYC RS02680
gene id: 259536:PSYC_RS02680
uniprot id: Q4FUD2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

259536:PSYC RS06485
gene id: 259536:PSYC_RS06485
uniprot id: Q4FSA9
names: Function
names: Similarity
messages: In the C-terminal section; belongs to the aldehyde dehydrogenase family.
messages: In the N-terminal section; belongs to the proline dehydrogenase family.
messages: Oxidizes proline to glutamate for use as a carbon and nitrogen source.

259536:PSYC RS07915
gene id: 259536:PSYC_RS07915
uniprot id: Q4FRI1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamA family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

259536:PSYC RS01385
gene id: 259536:PSYC_RS01385
uniprot id: Q4FV21
names: Similarity
messages: Belongs to the GSP E family.

259536:PSYC RS04130
gene id: 259536:PSYC_RS04130
uniprot id: Q4FTL3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the trans-sulfuration enzymes family. MetZ subfamily.
messages: Catalyzes the formation of L-homocysteine from O-succinyl-L-homoserine (OSHS) and hydrogen sulfide.
messages: Homotetramer.

259536:PSYC RS07275
gene id: 259536:PSYC_RS07275
uniprot id: Q4FRV7
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

259536:PSYC RS00950
gene id: 259536:PSYC_RS00950
uniprot id: Q4FVA1
names: Function
names: PTM
names: Similarity
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.

259536:PSYC RS03090
gene id: 259536:PSYC_RS03090
uniprot id: Q4FU60
names: Function
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

259536:PSYC RS08485
gene id: 259536:PSYC_RS08485
uniprot id: Q4FR75
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsB family.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

259536:PSYC RS06395
gene id: 259536:PSYC_RS06395
uniprot id: Q4FSC7
names: Subcellular Location Annotation
messages: Membrane

259536:PSYC RS06855
gene id: 259536:PSYC_RS06855
uniprot id: Q4FS36
names: Similarity
messages: Belongs to the peptidase S16 family.

259536:PSYC RS04300
gene id: 259536:PSYC_RS04300
uniprot id: Q4FTH9
names: Subcellular Location Annotation
messages: Membrane

259536:PSYC RS05050
gene id: 259536:PSYC_RS05050
uniprot id: Q4FT32
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

259536:PSYC RS05415
gene id: 259536:PSYC_RS05415
uniprot id: Q4FSW9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

259536:PSYC RS05650
gene id: 259536:PSYC_RS05650
uniprot id: Q4FSS2
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

259536:PSYC RS08730
gene id: 259536:PSYC_RS08730
uniprot id: Q4FR26
names: Subcellular Location Annotation
messages: Membrane

259536:PSYC RS01710
gene id: 259536:PSYC_RS01710
uniprot id: Q4FUV9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell inner membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

259536:PSYC RS05495
gene id: 259536:PSYC_RS05495
uniprot id: Q4FSV3
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

259536:PSYC RS00150
gene id: 259536:PSYC_RS00150
uniprot id: Q4FVQ6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

259536:PSYC RS08840
gene id: 259536:PSYC_RS08840
uniprot id: Q4FR04
names: Similarity
messages: Belongs to the KAE1 / TsaD family. TsaB subfamily.

259536:PSYC RS10510
gene id: 259536:PSYC_RS10510
uniprot id: Q4FQ31
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase A chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.

259536:PSYC RS07280
gene id: 259536:PSYC_RS07280
uniprot id: Q4FRV6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

259536:PSYC RS04935
gene id: 259536:PSYC_RS04935
uniprot id: Q4FT55
names: Similarity
messages: Belongs to the HSP15 family.

259536:PSYC RS09485
gene id: 259536:PSYC_RS09485
uniprot id: Q4FQM7
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

259536:PSYC RS08435
gene id: 259536:PSYC_RS08435
uniprot id: Q4FR84
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

259536:PSYC RS06345
gene id: 259536:PSYC_RS06345
uniprot id: Q4FSD7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dsrC/tusE family.
messages: Cytoplasm
messages: Part of a sulfur-relay system.

259536:PSYC RS03625
gene id: 259536:PSYC_RS03625
uniprot id: Q4FTV5
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

259536:PSYC RS03540
gene id: 259536:PSYC_RS03540
uniprot id: Q4FTX2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

259536:PSYC RS08660
gene id: 259536:PSYC_RS08660
uniprot id: Q4FR40
names: Function
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
messages: Catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate and ammonia.

259536:PSYC RS08120
gene id: 259536:PSYC_RS08120
uniprot id: Q4FRE3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxL/LpxM/LpxP family.
messages: Catalyzes the transfer of laurate from lauroyl-acyl carrier protein (ACP) to Kdo(2)-lipid IV(A) to form Kdo(2)-(lauroyl)-lipid IV(A).
messages: Cell inner membrane

259536:PSYC RS01090
gene id: 259536:PSYC_RS01090
uniprot id: Q4FV74
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

259536:PSYC RS03700
gene id: 259536:PSYC_RS03700
uniprot id: Q4FTU0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

259536:PSYC RS02150
gene id: 259536:PSYC_RS02150
uniprot id: Q4FUM9
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

259536:PSYC RS06930
gene id: 259536:PSYC_RS06930
uniprot id: Q4FS21
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

259536:PSYC RS01260
gene id: 259536:PSYC_RS01260
uniprot id: Q4FV45
names: Subcellular Location Annotation
messages: Membrane

259536:PSYC RS00190
gene id: 259536:PSYC_RS00190
uniprot id: Q4FVP8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HesB/IscA family.
messages: Binds 1 iron-sulfur cluster per subunit.
messages: Homodimer.
messages: Required for insertion of 4Fe-4S clusters for at least IspG.

259536:PSYC RS10735
gene id: 259536:PSYC_RS10735
uniprot id: Q4FPZ0
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

259536:PSYC RS10625
gene id: 259536:PSYC_RS10625
uniprot id: Q4FQ09
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

259536:PSYC RS06555
gene id: 259536:PSYC_RS06555
uniprot id: Q4FS95
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

259536:PSYC RS08820
gene id: 259536:PSYC_RS08820
uniprot id: Q4FR08
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family.
messages: Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.
messages: Cell inner membrane

259536:PSYC RS08925
gene id: 259536:PSYC_RS08925
uniprot id: Q4FQY7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

259536:PSYC RS07680
gene id: 259536:PSYC_RS07680
uniprot id: Q4FRM9
names: Function
names: Similarity
messages: Belongs to the heat shock protein 70 family.
messages: Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB.

259536:PSYC RS01150
gene id: 259536:PSYC_RS01150
uniprot id: Q4FV62
names: Similarity
messages: Belongs to the long-chain O-acyltransferase family.

259536:PSYC RS04350
gene id: 259536:PSYC_RS04350
uniprot id: Q4FTG9
names: Subcellular Location Annotation
messages: Membrane

259536:PSYC RS06490
gene id: 259536:PSYC_RS06490
uniprot id: Q4FSA8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbB/TolQ family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

259536:PSYC RS10055
gene id: 259536:PSYC_RS10055
uniprot id: Q4FQB6
names: Subcellular Location Annotation
messages: Membrane

259536:PSYC RS09500
gene id: 259536:PSYC_RS09500
uniprot id: Q4FQM4
names: Subcellular Location Annotation
messages: Membrane

259536:PSYC RS01780
gene id: 259536:PSYC_RS01780
uniprot id: Q4FUU5
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily.
messages: Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA.

259536:PSYC RS06465
gene id: 259536:PSYC_RS06465
uniprot id: Q4FSB3
names: Function
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
messages: Catalyzes two reactions in de novo purine nucleotide biosynthesis. Catalyzes the breakdown of 5-aminoimidazole- (N-succinylocarboxamide) ribotide (SAICAR or 2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate) to 5-aminoimidazole-4-carboxamide ribotide (AICAR or 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide) and fumarate, and of adenylosuccinate (ADS or N(6)-(1,2-dicarboxyethyl)-AMP) to adenosine monophosphate (AMP) and fumarate.

259536:PSYC RS08515
gene id: 259536:PSYC_RS08515
uniprot id: Q4FR69
names: Activity Regulation
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.

259536:PSYC RS06840
gene id: 259536:PSYC_RS06840
uniprot id: Q4FS39
names: Function
names: Similarity
messages: Belongs to the ParB family.
messages: Involved in chromosome partition. Localize to both poles of the predivisional cell following completion of DNA replication. Binds to the DNA origin of replication.

259536:PSYC RS02820
gene id: 259536:PSYC_RS02820
uniprot id: Q4FUA6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FBPase class 1 family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.

259536:PSYC RS00360
gene id: 259536:PSYC_RS00360
uniprot id: Q4FVL6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

259536:PSYC RS09760
gene id: 259536:PSYC_RS09760
uniprot id: Q4FQH4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

259536:PSYC RS08020
gene id: 259536:PSYC_RS08020
uniprot id: Q4FRG1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Cell inner membrane
messages: Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.

259536:PSYC RS04225
gene id: 259536:PSYC_RS04225
uniprot id: Q4FTJ5
names: Subcellular Location Annotation
messages: Membrane

259536:PSYC RS03155
gene id: 259536:PSYC_RS03155
uniprot id: Q4FU47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
messages: Membrane

259536:PSYC RS07935
gene id: 259536:PSYC_RS07935
uniprot id: Q4FRH7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di-trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

259536:PSYC RS04360
gene id: 259536:PSYC_RS04360
uniprot id: Q4FTG7
names: Similarity
messages: Belongs to the prokaryotic/mitochondrial release factor family.

259536:PSYC RS03660
gene id: 259536:PSYC_RS03660
uniprot id: Q4FTU8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

259536:PSYC RS00455
gene id: 259536:PSYC_RS00455
uniprot id: Q4FVJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

259536:PSYC RS07790
gene id: 259536:PSYC_RS07790
uniprot id: Q4FRK7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

259536:PSYC RS00670
gene id: 259536:PSYC_RS00670
uniprot id: Q4FVF3
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

259536:PSYC RS00540
gene id: 259536:PSYC_RS00540
uniprot id: Q4FVH9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

259536:PSYC RS02735
gene id: 259536:PSYC_RS02735
uniprot id: Q4FUC1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueG family.
messages: Binds 2 [4Fe-4S] clusters per monomer.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

259536:PSYC RS00485
gene id: 259536:PSYC_RS00485
uniprot id: Q4FVJ0
names: Function
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.
messages: DNA-dependent ATPase that plays important roles in cellular responses to stalled DNA replication processes.

259536:PSYC RS07885
gene id: 259536:PSYC_RS07885
uniprot id: Q4FRI7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

259536:PSYC RS00305
gene id: 259536:PSYC_RS00305
uniprot id: Q4FVM5
names: Function
names: Similarity
messages: Belongs to the nucleoside phosphorylase PpnP family.
messages: Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions.

259536:PSYC RS10000
gene id: 259536:PSYC_RS10000
uniprot id: Q4FQC7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. Thiolase family.
messages: Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed.
messages: Cytoplasm
messages: Heterotetramer of two alpha chains (FadB) and two beta chains (FadA).

259536:PSYC RS10345
gene id: 259536:PSYC_RS10345
uniprot id: Q4FQ64
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

259536:PSYC RS02605
gene id: 259536:PSYC_RS02605
uniprot id: Q4FUE7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

259536:PSYC RS08725
gene id: 259536:PSYC_RS08725
uniprot id: Q4FR27
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

259536:PSYC RS11030
gene id: 259536:PSYC_RS11030
uniprot id: Q4FPU1
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

259536:PSYC RS01010
gene id: 259536:PSYC_RS01010
uniprot id: Q4FV89
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Homohexamer.
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the CobB/CobQ family.
messages: Involved in acetate metabolism.
messages: The N-terminal region seems to be important for proper quaternary structure. The C-terminal region contains the substrate-binding site.

259536:PSYC RS10410
gene id: 259536:PSYC_RS10410
uniprot id: Q4FQ51
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell inner membrane

259536:PSYC RS10330
gene id: 259536:PSYC_RS10330
uniprot id: Q4FQ67
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

259536:PSYC RS00920
gene id: 259536:PSYC_RS00920
uniprot id: Q4FVA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0394 family.
messages: Membrane

259536:PSYC RS10440
gene id: 259536:PSYC_RS10440
uniprot id: Q4FQ45
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

259536:PSYC RS06260
gene id: 259536:PSYC_RS06260
uniprot id: Q4FSF4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.

259536:PSYC RS00615
gene id: 259536:PSYC_RS00615
uniprot id: Q4FVG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbA subfamily.
messages: Periplasm

259536:PSYC RS06910
gene id: 259536:PSYC_RS06910
uniprot id: Q4FS25
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

259536:PSYC RS07340
gene id: 259536:PSYC_RS07340
uniprot id: Q4FRU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OmpP1/FadL family.
messages: Cell outer membrane
messages: Membrane

259536:PSYC RS01735
gene id: 259536:PSYC_RS01735
uniprot id: Q4FUV4
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

259536:PSYC RS06750
gene id: 259536:PSYC_RS06750
uniprot id: Q4FS57
names: Subcellular Location Annotation
messages: Membrane

259536:PSYC RS03925
gene id: 259536:PSYC_RS03925
uniprot id: Q4FTQ3
names: Cofactor
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Binds 1 [4Fe-4S] cluster per subunit.

259536:PSYC RS02780
gene id: 259536:PSYC_RS02780
uniprot id: Q4FUB2
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

259536:PSYC RS07385
gene id: 259536:PSYC_RS07385
uniprot id: Q4FRT5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Catalyzes the deamination of dCTP to dUTP.
messages: Homotrimer.

259536:PSYC RS08200
gene id: 259536:PSYC_RS08200
uniprot id: Q4FRC8
names: Subcellular Location Annotation
messages: Membrane

259536:PSYC RS08895
gene id: 259536:PSYC_RS08895
uniprot id: Q4FQZ3
names: Function
names: Similarity
messages: Belongs to the esterase D family.
messages: Serine hydrolase involved in the detoxification of formaldehyde.

259536:PSYC RS02880
gene id: 259536:PSYC_RS02880
uniprot id: Q4FU94
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

259536:PSYC RS00260
gene id: 259536:PSYC_RS00260
uniprot id: Q4FVN4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

259536:PSYC RS03175
gene id: 259536:PSYC_RS03175
uniprot id: Q4FU43
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
messages: Cell membrane
messages: Membrane

259536:PSYC RS02675
gene id: 259536:PSYC_RS02675
uniprot id: Q4FUD3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

259536:PSYC RS03525
gene id: 259536:PSYC_RS03525
uniprot id: Q4FTX5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mediates influx of magnesium ions.
messages: Membrane

259536:PSYC RS09575
gene id: 259536:PSYC_RS09575
uniprot id: Q4FQL0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

259536:PSYC RS06320
gene id: 259536:PSYC_RS06320
uniprot id: Q4FSE2
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

259536:PSYC RS08845
gene id: 259536:PSYC_RS08845
uniprot id: Q4FR03
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

259536:PSYC RS00910
gene id: 259536:PSYC_RS00910
uniprot id: Q4FVA9
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

259536:PSYC RS04860
gene id: 259536:PSYC_RS04860
uniprot id: Q4FT70
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

259536:PSYC RS10480
gene id: 259536:PSYC_RS10480
uniprot id: Q4FQ37
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

259536:PSYC RS07900
gene id: 259536:PSYC_RS07900
uniprot id: Q4FRI4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
messages: Cytoplasm
messages: Homotrimer.
messages: Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

259536:PSYC RS05920
gene id: 259536:PSYC_RS05920
uniprot id: Q4FSL9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PEPCase type 1 family.
messages: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
messages: Homotetramer.

259536:PSYC RS08450
gene id: 259536:PSYC_RS08450
uniprot id: Q4FR81
names: Similarity
messages: Belongs to the YkuD family.

259536:PSYC RS03570
gene id: 259536:PSYC_RS03570
uniprot id: Q4FTW6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

259536:PSYC RS04215
gene id: 259536:PSYC_RS04215
uniprot id: Q4FTJ7
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

259536:PSYC RS08090
gene id: 259536:PSYC_RS08090
uniprot id: Q4FRE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.
messages: Cell inner membrane
messages: Membrane

259536:PSYC RS02560
gene id: 259536:PSYC_RS02560
uniprot id: Q4FUF6
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: Methylated by PrmB.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

259536:PSYC RS10745
gene id: 259536:PSYC_RS10745
uniprot id: Q4FPY8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.

259536:PSYC RS01895
gene id: 259536:PSYC_RS01895
uniprot id: Q4FUS3
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

259536:PSYC RS01130
gene id: 259536:PSYC_RS01130
uniprot id: Q4FV66
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the aerobic coproporphyrinogen-III oxidase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

259536:PSYC RS10080
gene id: 259536:PSYC_RS10080
uniprot id: Q4FQB1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Cx-SAM synthase family.
messages: Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM).
messages: Homodimer.

259536:PSYC RS10005
gene id: 259536:PSYC_RS10005
uniprot id: Q4FQC6
names: Function
names: Similarity
names: Subunit
messages: Heterotetramer of two alpha chains (FadB) and two beta chains (FadA).
messages: In the C-terminal section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family.
messages: In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.
messages: Involved in the aerobic and anaerobic degradation of long-chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate.

259536:PSYC RS09545
gene id: 259536:PSYC_RS09545
uniprot id: Q4FQL6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

259536:PSYC RS10035
gene id: 259536:PSYC_RS10035
uniprot id: Q4FQC0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

259536:PSYC RS05435
gene id: 259536:PSYC_RS05435
uniprot id: Q4FSW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

259536:PSYC RS01625
gene id: 259536:PSYC_RS01625
uniprot id: Q4FUX4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

259536:PSYC RS06245
gene id: 259536:PSYC_RS06245
uniprot id: Q4FSF7
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

259536:PSYC RS04780
gene id: 259536:PSYC_RS04780
uniprot id: Q4FT86
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.

259536:PSYC RS04890
gene id: 259536:PSYC_RS04890
uniprot id: Q4FT64
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

259536:PSYC RS08220
gene id: 259536:PSYC_RS08220
uniprot id: Q4FRC4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell inner membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

259536:PSYC RS01965
gene id: 259536:PSYC_RS01965
uniprot id: Q4FUQ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

259536:PSYC RS10270
gene id: 259536:PSYC_RS10270
uniprot id: Q4FQ79
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.
messages: Cytoplasm
messages: Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity.

259536:PSYC RS05585
gene id: 259536:PSYC_RS05585
uniprot id: Q4FST5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic sulfate-binding protein family.
messages: Periplasm

259536:PSYC RS00170
gene id: 259536:PSYC_RS00170
uniprot id: Q4FVQ2
names: Function
names: Similarity
messages: Belongs to the MurCDEF family. Mpl subfamily.
messages: Reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl-meso-diaminopimelate by linking it to UDP-N-acetylmuramate.

259536:PSYC RS01335
gene id: 259536:PSYC_RS01335
uniprot id: Q4FV31
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

259536:PSYC RS09510
gene id: 259536:PSYC_RS09510
uniprot id: Q4FQM2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell inner membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

259536:PSYC RS08830
gene id: 259536:PSYC_RS08830
uniprot id: Q4FR06
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmJ family.
messages: Cytoplasm
messages: Specifically methylates the guanosine in position 1516 of 16S rRNA.

259536:PSYC RS02635
gene id: 259536:PSYC_RS02635
uniprot id: Q4FUE1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

259536:PSYC RS11055
gene id: 259536:PSYC_RS11055
uniprot id: Q4FPT7
names: Function
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family.
messages: Specifically catalyzes the dephosphorylation of 2-phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress.

259536:PSYC RS05470
gene id: 259536:PSYC_RS05470
uniprot id: Q4FSV7
names: Subcellular Location Annotation
messages: Membrane

259536:PSYC RS01015
gene id: 259536:PSYC_RS01015
uniprot id: Q4FV88
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

259536:PSYC RS04925
gene id: 259536:PSYC_RS04925
uniprot id: Q4FT57
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

259536:PSYC RS08815
gene id: 259536:PSYC_RS08815
uniprot id: Q4FR09
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Catalyzes the last two steps in the biosynthesis of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the DAO family.
messages: In the N-terminal section; belongs to the methyltransferase superfamily. tRNA (mnm(5)s(2)U34)-methyltransferase family.

259536:PSYC RS08110
gene id: 259536:PSYC_RS08110
uniprot id: Q4FRE5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

259536:PSYC RS00315
gene id: 259536:PSYC_RS00315
uniprot id: Q4FVM3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

259536:PSYC RS11270
gene id: 259536:PSYC_RS11270
uniprot id: Q4FPZ1
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

259536:PSYC RS07090
gene id: 259536:PSYC_RS07090
uniprot id: Q4FRZ2
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

259536:PSYC RS05520
gene id: 259536:PSYC_RS05520
uniprot id: Q4FSU8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA gyrase inhibitor YacG family.
messages: Binds 1 zinc ion.
messages: Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.
messages: Interacts with GyrB.

259536:PSYC RS09875
gene id: 259536:PSYC_RS09875
uniprot id: Q4FQF2
names: Similarity
messages: Belongs to the UPF0102 family.

259536:PSYC RS11775
gene id: 259536:PSYC_RS11775
uniprot id: Q4FTX8
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

259536:PSYC RS00560
gene id: 259536:PSYC_RS00560
uniprot id: Q4FVH5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

259536:PSYC RS04830
gene id: 259536:PSYC_RS04830
uniprot id: Q4FT76
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. MrdB/RodA subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell wall elongation.

259536:PSYC RS04120
gene id: 259536:PSYC_RS04120
uniprot id: Q4FTL5
names: Subcellular Location Annotation
messages: Membrane

259536:PSYC RS00600
gene id: 259536:PSYC_RS00600
uniprot id: Q4FVG7
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

259536:PSYC RS06795
gene id: 259536:PSYC_RS06795
uniprot id: Q4FS48
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

259536:PSYC RS00820
gene id: 259536:PSYC_RS00820
uniprot id: Q4FVC3
names: Similarity
messages: Belongs to the GppA/Ppx family.

259536:PSYC RS03795
gene id: 259536:PSYC_RS03795
uniprot id: Q4FTS7
names: Subcellular Location Annotation
messages: Membrane

259536:PSYC RS09440
gene id: 259536:PSYC_RS09440
uniprot id: Q4FQN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NlpA lipoprotein family.
messages: Membrane

259536:PSYC RS02305
gene id: 259536:PSYC_RS02305
uniprot id: Q4FUK0
names: Similarity
messages: Belongs to the peptidase C40 family.

259536:PSYC RS03615
gene id: 259536:PSYC_RS03615
uniprot id: Q4FTV7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxH family.
messages: Binds 2 Mn(2+) ions per subunit in a binuclear metal center.
messages: Cell inner membrane
messages: Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

259536:PSYC RS07050
gene id: 259536:PSYC_RS07050
uniprot id: Q4FS00
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

259536:PSYC RS11120
gene id: 259536:PSYC_RS11120
uniprot id: Q4FPS4
names: Similarity
messages: Belongs to the threonine synthase family.

259536:PSYC RS06660
gene id: 259536:PSYC_RS06660
uniprot id: Q4FS74
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

259536:PSYC RS01310
gene id: 259536:PSYC_RS01310
uniprot id: Q4FV36
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

259536:PSYC RS07750
gene id: 259536:PSYC_RS07750
uniprot id: Q4FRL5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

259536:PSYC RS07660
gene id: 259536:PSYC_RS07660
uniprot id: Q4FRN3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
messages: Cytoplasm
messages: Homodimer. Forms a heterotetramer with IscU, interacts with other sulfur acceptors.
messages: Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.

259536:PSYC RS06125
gene id: 259536:PSYC_RS06125
uniprot id: Q4FSI1
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaved by autocatalysis into a large and a small subunit.
messages: This enzyme consists of two polypeptide chains, which are synthesized in precursor form from a single polypeptide.

259536:PSYC RS06535
gene id: 259536:PSYC_RS06535
uniprot id: Q4FS99
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

259536:PSYC RS11085
gene id: 259536:PSYC_RS11085
uniprot id: Q4FPT1
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

259536:PSYC RS06325
gene id: 259536:PSYC_RS06325
uniprot id: Q4FSE1
names: Function
names: Similarity
messages: Belongs to the GlnE family.
messages: Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell.

259536:PSYC RS04245
gene id: 259536:PSYC_RS04245
uniprot id: Q4FTJ1
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

259536:PSYC RS09855
gene id: 259536:PSYC_RS09855
uniprot id: Q4FQF6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm

259536:PSYC RS00895
gene id: 259536:PSYC_RS00895
uniprot id: Q4FVB2
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

259536:PSYC RS04100
gene id: 259536:PSYC_RS04100
uniprot id: Q4FTL9
names: Similarity
messages: Belongs to the peptidase S49 family.

259536:PSYC RS10505
gene id: 259536:PSYC_RS10505
uniprot id: Q4FQ32
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase C chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

259536:PSYC RS07760
gene id: 259536:PSYC_RS07760
uniprot id: Q4FRL3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

259536:PSYC RS08050
gene id: 259536:PSYC_RS08050
uniprot id: Q4FRF7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

259536:PSYC RS06145
gene id: 259536:PSYC_RS06145
uniprot id: Q4FSH7
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

259536:PSYC RS03800
gene id: 259536:PSYC_RS03800
uniprot id: Q4FTS6
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

259536:PSYC RS03675
gene id: 259536:PSYC_RS03675
uniprot id: Q4FTU5
names: Similarity
messages: Belongs to the peptidase S11 family.

259536:PSYC RS06225
gene id: 259536:PSYC_RS06225
uniprot id: Q4FSG1
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

259536:PSYC RS01685
gene id: 259536:PSYC_RS01685
uniprot id: Q4FUW3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

259536:PSYC RS01425
gene id: 259536:PSYC_RS01425
uniprot id: Q4FV13
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.

259536:PSYC RS09240
gene id: 259536:PSYC_RS09240
uniprot id: Q4FQS6
names: Similarity
messages: Belongs to the BolA/IbaG family.

259536:PSYC RS02705
gene id: 259536:PSYC_RS02705
uniprot id: Q4FUC7
names: Function
names: Similarity
messages: Belongs to the DUF177 domain family.
messages: Plays a role in synthesis, processing and/or stability of 23S rRNA.

259536:PSYC RS09720
gene id: 259536:PSYC_RS09720
uniprot id: Q4FQI2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Monomer.

259536:PSYC RS03815
gene id: 259536:PSYC_RS03815
uniprot id: Q4FTS3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

259536:PSYC RS10945
gene id: 259536:PSYC_RS10945
uniprot id: Q4FPV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

259536:PSYC RS08100
gene id: 259536:PSYC_RS08100
uniprot id: Q4FRE7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transpeptidase family. MrdA subfamily.
messages: Catalyzes cross-linking of the peptidoglycan cell wall.
messages: Cell inner membrane

259536:PSYC RS10305
gene id: 259536:PSYC_RS10305
uniprot id: Q4FQ72
names: Similarity
messages: Belongs to the thioredoxin family.

259536:PSYC RS03075
gene id: 259536:PSYC_RS03075
uniprot id: Q4FU63
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

259536:PSYC RS06620
gene id: 259536:PSYC_RS06620
uniprot id: Q4FS82
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YajC family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the SecDF-YidC-YajC translocase complex. The SecDF-YidC-YajC translocase forms a supercomplex with SecYEG, called the holo-translocon (HTL).
messages: The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions.

259536:PSYC RS07580
gene id: 259536:PSYC_RS07580
uniprot id: Q4FRP9
names: Similarity
messages: Belongs to the aspartokinase family.

259536:PSYC RS06655
gene id: 259536:PSYC_RS06655
uniprot id: Q4FS75
names: Subcellular Location Annotation
messages: Membrane

259536:PSYC RS10395
gene id: 259536:PSYC_RS10395
uniprot id: Q4FQ54
names: Function
names: Similarity
messages: Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
messages: Belongs to the Nudix hydrolase family. RppH subfamily.

259536:PSYC RS01120
gene id: 259536:PSYC_RS01120
uniprot id: Q4FV68
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.

259536:PSYC RS10655
gene id: 259536:PSYC_RS10655
uniprot id: Q4FQ04
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Monomer.

259536:PSYC RS10085
gene id: 259536:PSYC_RS10085
uniprot id: Q4FQB0
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

259536:PSYC RS04765
gene id: 259536:PSYC_RS04765
uniprot id: Q4FT89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0060 family.
messages: Cell inner membrane

259536:PSYC RS09585
gene id: 259536:PSYC_RS09585
uniprot id: Q4FQK8
names: Similarity
messages: Belongs to the UPF0145 family.

259536:PSYC RS02070
gene id: 259536:PSYC_RS02070
uniprot id: Q4FUP4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

259536:PSYC RS04415
gene id: 259536:PSYC_RS04415
uniprot id: Q4FTF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

259536:PSYC RS05735
gene id: 259536:PSYC_RS05735
uniprot id: Q4FSQ5
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

259536:PSYC RS09385
gene id: 259536:PSYC_RS09385
uniprot id: Q4FQP7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

259536:PSYC RS02610
gene id: 259536:PSYC_RS02610
uniprot id: Q4FUE6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

259536:PSYC RS09840
gene id: 259536:PSYC_RS09840
uniprot id: Q4FQF9
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

259536:PSYC RS06180
gene id: 259536:PSYC_RS06180
uniprot id: Q4FSH0
names: Function
names: Similarity
messages: Belongs to the transaldolase family. Type 1 subfamily.
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

259536:PSYC RS01370
gene id: 259536:PSYC_RS01370
uniprot id: Q4FV24
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamE family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

259536:PSYC RS01820
gene id: 259536:PSYC_RS01820
uniprot id: Q4FUT7
names: Similarity
messages: Belongs to the transglycosylase Slt family.

259536:PSYC RS06885
gene id: 259536:PSYC_RS06885
uniprot id: Q4FS30
names: Function
names: Subunit
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
messages: Homodimer. Part of the PDH complex, consisting of multiple copies of pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

259536:PSYC RS00870
gene id: 259536:PSYC_RS00870
uniprot id: Q4FVB5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

259536:PSYC RS11065
gene id: 259536:PSYC_RS11065
uniprot id: Q4FPT5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family.
messages: Cytoplasm
messages: Monomer.

259536:PSYC RS04750
gene id: 259536:PSYC_RS04750
uniprot id: Q4FT92
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. NspC subfamily.
messages: Catalyzes the decarboxylation of carboxynorspermidine and carboxyspermidine.
messages: Cytoplasm
messages: Homodimer.

259536:PSYC RS06630
gene id: 259536:PSYC_RS06630
uniprot id: Q4FS80
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

259536:PSYC RS02930
gene id: 259536:PSYC_RS02930
uniprot id: Q4FU84
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RlmJ family.
messages: Monomer.
messages: Specifically methylates the adenine in position 2030 of 23S rRNA.

259536:PSYC RS10975
gene id: 259536:PSYC_RS10975
uniprot id: Q4FPV2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrF family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Cell inner membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway.

259536:PSYC RS00050
gene id: 259536:PSYC_RS00050
uniprot id: Q4FVS6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. METTL16/RlmF family.
messages: Cytoplasm
messages: Specifically methylates the adenine in position 1618 of 23S rRNA.

259536:PSYC RS08060
gene id: 259536:PSYC_RS08060
uniprot id: Q4FRF5
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.

259536:PSYC RS01715
gene id: 259536:PSYC_RS01715
uniprot id: Q4FUV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

259536:PSYC RS06720
gene id: 259536:PSYC_RS06720
uniprot id: Q4FS62
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

259536:PSYC RS09555
gene id: 259536:PSYC_RS09555
uniprot id: Q4FQL4
names: Subcellular Location Annotation
messages: Cytoplasm

259536:PSYC RS02890
gene id: 259536:PSYC_RS02890
uniprot id: Q4FU92
names: Similarity
messages: Belongs to the AlaDH/PNT family.

259536:PSYC RS05765
gene id: 259536:PSYC_RS05765
uniprot id: Q4FSP9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

259536:PSYC RS00460
gene id: 259536:PSYC_RS00460
uniprot id: Q4FVJ5
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

259536:PSYC RS05035
gene id: 259536:PSYC_RS05035
uniprot id: Q4FT35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

259536:PSYC RS03620
gene id: 259536:PSYC_RS03620
uniprot id: Q4FTV6
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

259536:PSYC RS01445
gene id: 259536:PSYC_RS01445
uniprot id: Q4FV10
names: Subcellular Location Annotation
messages: Membrane

259536:PSYC RS04950
gene id: 259536:PSYC_RS04950
uniprot id: Q4FT52
names: Similarity
messages: Belongs to the ArsC family.

259536:PSYC RS06825
gene id: 259536:PSYC_RS06825
uniprot id: Q4FS42
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Lipid exporter (TC 3.A.1.106) family.
messages: Cell inner membrane
messages: Homodimer.
messages: In MsbA the ATP-binding domain (NBD) and the transmembrane domain (TMD) are fused.
messages: Involved in lipopolysaccharide (LPS) biosynthesis. Translocates lipid A-core from the inner to the outer leaflet of the inner membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation.

259536:PSYC RS01805
gene id: 259536:PSYC_RS01805
uniprot id: Q4FUU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell inner membrane
messages: Membrane

259536:PSYC RS02215
gene id: 259536:PSYC_RS02215
uniprot id: Q4FUL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

259536:PSYC RS08550
gene id: 259536:PSYC_RS08550
uniprot id: Q4FR62
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 51 family.
messages: Cell inner membrane
messages: Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors.

259536:PSYC RS01605
gene id: 259536:PSYC_RS01605
uniprot id: Q4FUX8
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

259536:PSYC RS02740
gene id: 259536:PSYC_RS02740
uniprot id: Q4FUC0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.

259536:PSYC RS02825
gene id: 259536:PSYC_RS02825
uniprot id: Q4FUA5
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

259536:PSYC RS01470
gene id: 259536:PSYC_RS01470
uniprot id: Q4FV05
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

259536:PSYC RS10150
gene id: 259536:PSYC_RS10150
uniprot id: Q4FQ98
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

259536:PSYC RS02090
gene id: 259536:PSYC_RS02090
uniprot id: Q4FUN8
names: Domain
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
messages: Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.

259536:PSYC RS07675
gene id: 259536:PSYC_RS07675
uniprot id: Q4FRN0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HscB family.
messages: Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA.
messages: Interacts with HscA and stimulates its ATPase activity.

259536:PSYC RS07345
gene id: 259536:PSYC_RS07345
uniprot id: Q4FRU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OmpP1/FadL family.
messages: Cell outer membrane
messages: Membrane

259536:PSYC RS02935
gene id: 259536:PSYC_RS02935
uniprot id: Q4FU83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

259536:PSYC RS04115
gene id: 259536:PSYC_RS04115
uniprot id: Q4FTL6
names: Caution
names: Function
names: Similarity
messages: Belongs to the Dus family. DusA subfamily.
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

259536:PSYC RS01850
gene id: 259536:PSYC_RS01850
uniprot id: Q4FUT1
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

259536:PSYC RS07795
gene id: 259536:PSYC_RS07795
uniprot id: Q4FRK6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

259536:PSYC RS01790
gene id: 259536:PSYC_RS01790
uniprot id: Q4FUU3
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

259536:PSYC RS06425
gene id: 259536:PSYC_RS06425
uniprot id: Q4FSC1
names: Similarity
messages: Belongs to the bacterial PQQ dehydrogenase family.

259536:PSYC RS08165
gene id: 259536:PSYC_RS08165
uniprot id: Q4FRD4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

259536:PSYC RS08460
gene id: 259536:PSYC_RS08460
uniprot id: Q4FR79
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.

259536:PSYC RS06450
gene id: 259536:PSYC_RS06450
uniprot id: Q4FSB6
names: Similarity
messages: Belongs to the glutaredoxin family. Monothiol subfamily.

259536:PSYC RS02620
gene id: 259536:PSYC_RS02620
uniprot id: Q4FUE4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

259536:PSYC RS10965
gene id: 259536:PSYC_RS10965
uniprot id: Q4FPV4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Membrane
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

259536:PSYC RS08465
gene id: 259536:PSYC_RS08465
uniprot id: Q4FR78
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Homodimer.

259536:PSYC RS02590
gene id: 259536:PSYC_RS02590
uniprot id: Q4FUF0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

259536:PSYC RS00385
gene id: 259536:PSYC_RS00385
uniprot id: Q4FVL1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

259536:PSYC RS02115
gene id: 259536:PSYC_RS02115
uniprot id: Q4FUN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

259536:PSYC RS06905
gene id: 259536:PSYC_RS06905
uniprot id: Q4FS26
names: Similarity
messages: Belongs to the FGGY kinase family.

259536:PSYC RS06650
gene id: 259536:PSYC_RS06650
uniprot id: Q4FS76
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

259536:PSYC RS02625
gene id: 259536:PSYC_RS02625
uniprot id: Q4FUE3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

259536:PSYC RS00200
gene id: 259536:PSYC_RS00200
uniprot id: Q4FVP6
names: Function
names: Similarity
messages: Belongs to the RlpA family.
messages: Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.

259536:PSYC RS06705
gene id: 259536:PSYC_RS06705
uniprot id: Q4FS65
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

259536:PSYC RS03915
gene id: 259536:PSYC_RS03915
uniprot id: Q4FTQ5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

259536:PSYC RS07850
gene id: 259536:PSYC_RS07850
uniprot id: Q4FRJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

259536:PSYC RS06315
gene id: 259536:PSYC_RS06315
uniprot id: Q4FSE3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

259536:PSYC RS10955
gene id: 259536:PSYC_RS10955
uniprot id: Q4FPV6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell inner membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

259536:PSYC RS06130
gene id: 259536:PSYC_RS06130
uniprot id: Q4FSI0
names: Subcellular Location Annotation
messages: Cytoplasm

259536:PSYC RS09945
gene id: 259536:PSYC_RS09945
uniprot id: Q4FQD8
names: Function
messages: Member of the two-component regulatory system PhoR/PhoB involved in the phosphate regulon genes expression. PhoR may function as a membrane-associated protein kinase that phosphorylates PhoB in response to environmental signals.

259536:PSYC RS07080
gene id: 259536:PSYC_RS07080
uniprot id: Q4FRZ4
names: Function
names: Similarity
messages: Belongs to the SELO family.
messages: Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).

259536:PSYC RS04845
gene id: 259536:PSYC_RS04845
uniprot id: Q4FT73
names: Similarity
messages: Belongs to the peptidase M16 family.

259536:PSYC RS04760
gene id: 259536:PSYC_RS04760
uniprot id: Q4FT90
names: Similarity
messages: Belongs to the PhzF family.

259536:PSYC RS09265
gene id: 259536:PSYC_RS09265
uniprot id: Q4FQS1
names: Similarity
messages: Belongs to the thioredoxin family.

259536:PSYC RS08410
gene id: 259536:PSYC_RS08410
uniprot id: Q4FR89
names: Similarity
messages: Belongs to the UPF0319 family.

259536:PSYC RS09495
gene id: 259536:PSYC_RS09495
uniprot id: Q4FQM5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

259536:PSYC RS06460
gene id: 259536:PSYC_RS06460
uniprot id: Q4FSB4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm

259536:PSYC RS09650
gene id: 259536:PSYC_RS09650
uniprot id: Q4FQJ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

259536:PSYC RS10780
gene id: 259536:PSYC_RS10780
uniprot id: Q4FPY1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ApbE family.
messages: Cell inner membrane
messages: Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.
messages: Magnesium. Can also use manganese.

259536:PSYC RS01505
gene id: 259536:PSYC_RS01505
uniprot id: Q4FUZ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.

259536:PSYC RS08030
gene id: 259536:PSYC_RS08030
uniprot id: Q4FRF9
names: Subcellular Location Annotation
messages: Membrane

259536:PSYC RS07410
gene id: 259536:PSYC_RS07410
uniprot id: Q4FRT0
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit A family.

259536:PSYC RS03275
gene id: 259536:PSYC_RS03275
uniprot id: Q4FU25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

259536:PSYC RS07820
gene id: 259536:PSYC_RS07820
uniprot id: Q4FRK0
names: Subcellular Location Annotation
messages: Cell outer membrane

259536:PSYC RS07670
gene id: 259536:PSYC_RS07670
uniprot id: Q4FRN1
names: Similarity
messages: Belongs to the HesB/IscA family.

259536:PSYC RS03125
gene id: 259536:PSYC_RS03125
uniprot id: Q4FU53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

259536:PSYC RS08170
gene id: 259536:PSYC_RS08170
uniprot id: Q4FRD3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell outer membrane

259536:PSYC RS09480
gene id: 259536:PSYC_RS09480
uniprot id: Q4FQM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

259536:PSYC RS02665
gene id: 259536:PSYC_RS02665
uniprot id: Q4FUD5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

259536:PSYC RS03695
gene id: 259536:PSYC_RS03695
uniprot id: Q4FTU1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.
messages: One is catalytic and the other provides a structural contribution.

259536:PSYC RS09490
gene id: 259536:PSYC_RS09490
uniprot id: Q4FQM6
names: Similarity
messages: Belongs to the UPF0758 family.

259536:PSYC RS10445
gene id: 259536:PSYC_RS10445
uniprot id: Q4FQ44
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

259536:PSYC RS03835
gene id: 259536:PSYC_RS03835
uniprot id: Q4FTS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

259536:PSYC RS03085
gene id: 259536:PSYC_RS03085
uniprot id: Q4FU61
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

259536:PSYC RS06170
gene id: 259536:PSYC_RS06170
uniprot id: Q4FSH2
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

259536:PSYC RS06765
gene id: 259536:PSYC_RS06765
uniprot id: Q4FS54
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.

259536:PSYC RS08860
gene id: 259536:PSYC_RS08860
uniprot id: Q4FR00
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

259536:PSYC RS04315
gene id: 259536:PSYC_RS04315
uniprot id: Q4FTH6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

259536:PSYC RS04705
gene id: 259536:PSYC_RS04705
uniprot id: Q4FTA1
names: Similarity
messages: Belongs to the HIBADH-related family.

259536:PSYC RS05840
gene id: 259536:PSYC_RS05840
uniprot id: Q4FSN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

259536:PSYC RS04150
gene id: 259536:PSYC_RS04150
uniprot id: Q4FTK9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

259536:PSYC RS01320
gene id: 259536:PSYC_RS01320
uniprot id: Q4FV34
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbC subfamily.
messages: Periplasm
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process.

259536:PSYC RS07925
gene id: 259536:PSYC_RS07925
uniprot id: Q4FRH9
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).

259536:PSYC RS09795
gene id: 259536:PSYC_RS09795
uniprot id: Q4FQG7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

259536:PSYC RS04080
gene id: 259536:PSYC_RS04080
uniprot id: Q4FTM3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3.A.1.125) family.
messages: Cell inner membrane
messages: Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.
messages: The complex is composed of two ATP-binding proteins (LolD) and two transmembrane proteins (LolC and LolE).

259536:PSYC RS06625
gene id: 259536:PSYC_RS06625
uniprot id: Q4FS81
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

259536:PSYC RS00025
gene id: 259536:PSYC_RS00025
uniprot id: Q4FVT1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

259536:PSYC RS03045
gene id: 259536:PSYC_RS03045
uniprot id: Q4FU68
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

259536:PSYC RS00860
gene id: 259536:PSYC_RS00860
uniprot id: Q4FVB7
names: Subcellular Location Annotation
messages: Membrane

259536:PSYC RS11140
gene id: 259536:PSYC_RS11140
uniprot id: Q4FPS0
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

259536:PSYC RS10425
gene id: 259536:PSYC_RS10425
uniprot id: Q4FQ48
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

259536:PSYC RS02540
gene id: 259536:PSYC_RS02540
uniprot id: Q4FUG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Membrane

259536:PSYC RS03585
gene id: 259536:PSYC_RS03585
uniprot id: Q4FTW3
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

259536:PSYC RS09850
gene id: 259536:PSYC_RS09850
uniprot id: Q4FQF7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Lacks the C-terminal regulatory region which is replaced by HisZ.

259536:PSYC RS05900
gene id: 259536:PSYC_RS05900
uniprot id: Q4FSM3
names: Similarity
messages: Belongs to the DODA-type extradiol aromatic ring-opening dioxygenase family.

259536:PSYC RS04725
gene id: 259536:PSYC_RS04725
uniprot id: Q4FT97
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Pal lipoprotein family.
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

259536:PSYC RS07335
gene id: 259536:PSYC_RS07335
uniprot id: Q4FRU5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Catalyzes the sodium-dependent uptake of extracellular L-proline.
messages: Cell inner membrane
messages: Membrane

259536:PSYC RS10455
gene id: 259536:PSYC_RS10455
uniprot id: Q4FQ42
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

259536:PSYC RS01770
gene id: 259536:PSYC_RS01770
uniprot id: Q4FUU7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

259536:PSYC RS01650
gene id: 259536:PSYC_RS01650
uniprot id: Q4FUX0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZipA family.
messages: Cell inner membrane
messages: Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins.

259536:PSYC RS08085
gene id: 259536:PSYC_RS08085
uniprot id: Q4FRF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbE subfamily.
messages: Cell inner membrane

259536:PSYC RS02715
gene id: 259536:PSYC_RS02715
uniprot id: Q4FUC5
names: Similarity
messages: Belongs to the fabD family.

259536:PSYC RS10715
gene id: 259536:PSYC_RS10715
uniprot id: Q4FPZ4
names: Similarity
messages: Belongs to the pseudomonas-type ThrB family.

259536:PSYC RS08770
gene id: 259536:PSYC_RS08770
uniprot id: Q4FR18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThrE exporter (TC 2.A.79) family.
messages: Membrane

259536:PSYC RS06520
gene id: 259536:PSYC_RS06520
uniprot id: Q4FSA2
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

259536:PSYC RS00290
gene id: 259536:PSYC_RS00290
uniprot id: Q4FVM8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF nuclease family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

259536:PSYC RS10285
gene id: 259536:PSYC_RS10285
uniprot id: Q4FQ76
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

259536:PSYC RS00015
gene id: 259536:PSYC_RS00015
uniprot id: Q4FVT3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

259536:PSYC RS08510
gene id: 259536:PSYC_RS08510
uniprot id: Q4FR70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

259536:PSYC RS09630
gene id: 259536:PSYC_RS09630
uniprot id: Q4FQJ9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

259536:PSYC RS08930
gene id: 259536:PSYC_RS08930
uniprot id: Q4FQY6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

259536:PSYC RS05060
gene id: 259536:PSYC_RS05060
uniprot id: Q4FT30
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glutamine synthetase family.
messages: Cytoplasm
messages: Oligomer of 12 subunits arranged in the form of two hexagons.

259536:PSYC RS01380
gene id: 259536:PSYC_RS01380
uniprot id: Q4FV22
names: Similarity
messages: Belongs to the GSP E family.

259536:PSYC RS06255
gene id: 259536:PSYC_RS06255
uniprot id: Q4FSF5
names: Similarity
messages: Belongs to the peptidase S49 family.

259536:PSYC RS05500
gene id: 259536:PSYC_RS05500
uniprot id: Q4FSV2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

259536:PSYC RS01405
gene id: 259536:PSYC_RS01405
uniprot id: Q4FV17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

259536:PSYC RS02685
gene id: 259536:PSYC_RS02685
uniprot id: Q4FUD1
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

259536:PSYC RS00755
gene id: 259536:PSYC_RS00755
uniprot id: Q4FVD6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

259536:PSYC RS02570
gene id: 259536:PSYC_RS02570
uniprot id: Q4FUF4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

259536:PSYC RS01075
gene id: 259536:PSYC_RS01075
uniprot id: Q4FV77
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

259536:PSYC RS10045
gene id: 259536:PSYC_RS10045
uniprot id: Q4FQB8
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

259536:PSYC RS02230
gene id: 259536:PSYC_RS02230
uniprot id: Q4FUL5
names: Similarity
messages: Belongs to the DNA photolyase class-1 family.

259536:PSYC RS08805
gene id: 259536:PSYC_RS08805
uniprot id: Q4FR11
names: Similarity
messages: Belongs to the YciI family.

259536:PSYC RS08920
gene id: 259536:PSYC_RS08920
uniprot id: Q4FQY8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

259536:PSYC RS01290
gene id: 259536:PSYC_RS01290
uniprot id: Q4FV40
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell inner membrane
messages: Cytoplasm
messages: May bind 1 zinc ion per subunit.
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

259536:PSYC RS02670
gene id: 259536:PSYC_RS02670
uniprot id: Q4FUD4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

259536:PSYC RS07400
gene id: 259536:PSYC_RS07400
uniprot id: Q4FRT2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

259536:PSYC RS05935
gene id: 259536:PSYC_RS05935
uniprot id: Q4FSL6
names: Function
names: Similarity
messages: Belongs to the CitG/MdcB family.
messages: Involved in the formation of 2-(5''-phosphoribosyl)-3'-dephosphocoenzyme-A, the prosthetic group of the acyl-carrier protein of the malonate decarboxylase.

259536:PSYC RS01535
gene id: 259536:PSYC_RS01535
uniprot id: Q4FUZ2
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

259536:PSYC RS11005
gene id: 259536:PSYC_RS11005
uniprot id: Q4FPU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

259536:PSYC RS07545
gene id: 259536:PSYC_RS07545
uniprot id: Q4FRQ5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

259536:PSYC RS06515
gene id: 259536:PSYC_RS06515
uniprot id: Q4FSA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0394 family.
messages: Membrane

259536:PSYC RS04775
gene id: 259536:PSYC_RS04775
uniprot id: Q4FT87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

259536:PSYC RS07785
gene id: 259536:PSYC_RS07785
uniprot id: Q4FRK8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.

259536:PSYC RS08735
gene id: 259536:PSYC_RS08735
uniprot id: Q4FR25
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

259536:PSYC RS07270
gene id: 259536:PSYC_RS07270
uniprot id: Q4FRV8
names: Similarity
messages: Belongs to the pirin family.

259536:PSYC RS11145
gene id: 259536:PSYC_RS11145
uniprot id: Q4FPR9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

259536:PSYC RS09280
gene id: 259536:PSYC_RS09280
uniprot id: Q4FQR8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

259536:PSYC RS04160
gene id: 259536:PSYC_RS04160
uniprot id: Q4FTK7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

259536:PSYC RS08990
gene id: 259536:PSYC_RS08990
uniprot id: Q4FQX4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH and other flavinylated proteins as well.
messages: Belongs to the SdhE FAD assembly factor family.
messages: Cytoplasm

259536:PSYC RS09635
gene id: 259536:PSYC_RS09635
uniprot id: Q4FQJ8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HemJ family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Catalyzes the oxidation of protoporphyrinogen IX to protoporphyrin IX.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

259536:PSYC RS06385
gene id: 259536:PSYC_RS06385
uniprot id: Q4FSC9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homotetramer.

259536:PSYC RS05025
gene id: 259536:PSYC_RS05025
uniprot id: Q4FT37
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

259536:PSYC RS07010
gene id: 259536:PSYC_RS07010
uniprot id: Q4FS08
names: Similarity
messages: Belongs to the iron-containing alcohol dehydrogenase family.

259536:PSYC RS04670
gene id: 259536:PSYC_RS04670
uniprot id: Q4FTA8
names: Subcellular Location Annotation
messages: Membrane

259536:PSYC RS00530
gene id: 259536:PSYC_RS00530
uniprot id: Q4FVI1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

259536:PSYC RS01700
gene id: 259536:PSYC_RS01700
uniprot id: Q4FUW0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

259536:PSYC RS06370
gene id: 259536:PSYC_RS06370
uniprot id: Q4FSD2
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

259536:PSYC RS01575
gene id: 259536:PSYC_RS01575
uniprot id: Q4FUY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

259536:PSYC RS07985
gene id: 259536:PSYC_RS07985
uniprot id: Q4FRG8
names: Similarity
messages: Belongs to the GST superfamily.

259536:PSYC RS02225
gene id: 259536:PSYC_RS02225
uniprot id: Q4FUL6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

259536:PSYC RS00270
gene id: 259536:PSYC_RS00270
uniprot id: Q4FVN2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

259536:PSYC RS01110
gene id: 259536:PSYC_RS01110
uniprot id: Q4FV70
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell inner membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.

259536:PSYC RS06960
gene id: 259536:PSYC_RS06960
uniprot id: Q4FS17
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

259536:PSYC RS00515
gene id: 259536:PSYC_RS00515
uniprot id: Q4FVI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Cell inner membrane
messages: Membrane

259536:PSYC RS01800
gene id: 259536:PSYC_RS01800
uniprot id: Q4FUU1
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

259536:PSYC RS01135
gene id: 259536:PSYC_RS01135
uniprot id: Q4FV65
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the GTP cyclohydrolase II family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.

259536:PSYC RS09065
gene id: 259536:PSYC_RS09065
uniprot id: Q4FQV9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell inner membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).

259536:PSYC RS10360
gene id: 259536:PSYC_RS10360
uniprot id: Q4FQ61
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell inner membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

259536:PSYC RS04930
gene id: 259536:PSYC_RS04930
uniprot id: Q4FT56
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

259536:PSYC RS01945
gene id: 259536:PSYC_RS01945
uniprot id: Q4FUR3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Cytoplasm

259536:PSYC RS10725
gene id: 259536:PSYC_RS10725
uniprot id: Q4FPZ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
messages: Forms an icosahedral capsid composed of 60 subunits, arranged as a dodecamer of pentamers.

259536:PSYC RS03415
gene id: 259536:PSYC_RS03415
uniprot id: Q4FTZ7
names: Subcellular Location Annotation
messages: Membrane

259536:PSYC RS05810
gene id: 259536:PSYC_RS05810
uniprot id: Q4FSP0
names: Similarity
messages: Belongs to the PrpD family.

259536:PSYC RS01125
gene id: 259536:PSYC_RS01125
uniprot id: Q4FV67
names: Similarity
messages: Belongs to the glyoxalase I family.

259536:PSYC RS03010
gene id: 259536:PSYC_RS03010
uniprot id: Q4FU75
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Macrolide exporter (TC 3.A.1.122) family.
messages: Cell inner membrane
messages: Homodimer. Part of the tripartite efflux system MacAB-TolC, which is composed of an inner membrane transporter, MacB, a periplasmic membrane fusion protein, MacA, and an outer membrane component, TolC. The complex forms a large protein conduit and can translocate molecules across both the inner and outer membranes. Interacts with MacA.
messages: Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.

259536:PSYC RS04030
gene id: 259536:PSYC_RS04030
uniprot id: Q4FTN3
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TtcA family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is chelated by three Cys residues, the fourth Fe has a free coordination site that may bind a sulfur atom transferred from the persulfide of IscS.
messages: Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.
messages: Cytoplasm
messages: Homodimer.
messages: The thiolation reaction likely consists of two steps: a first activation step by ATP to form an adenylated intermediate of the target base of tRNA, and a second nucleophilic substitution step of the sulfur (S) atom supplied by the hydrosulfide attached to the Fe-S cluster.

259536:PSYC RS11125
gene id: 259536:PSYC_RS11125
uniprot id: Q4FPS3
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

259536:PSYC RS03545
gene id: 259536:PSYC_RS03545
uniprot id: Q4FTX1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

259536:PSYC RS01655
gene id: 259536:PSYC_RS01655
uniprot id: Q4FUW9
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

259536:PSYC RS00690
gene id: 259536:PSYC_RS00690
uniprot id: Q4FVE9
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

259536:PSYC RS04745
gene id: 259536:PSYC_RS04745
uniprot id: Q4FT93
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

259536:PSYC RS00880
gene id: 259536:PSYC_RS00880
uniprot id: Q4FVB3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

259536:PSYC RS00300
gene id: 259536:PSYC_RS00300
uniprot id: Q4FVM6
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

259536:PSYC RS04880
gene id: 259536:PSYC_RS04880
uniprot id: Q4FT66
names: Subcellular Location Annotation
messages: Membrane

259536:PSYC RS04630
gene id: 259536:PSYC_RS04630
uniprot id: Q4FTB6
names: Similarity
messages: Belongs to the GSP E family.

259536:PSYC RS04365
gene id: 259536:PSYC_RS04365
uniprot id: Q4FTG6
names: Subcellular Location Annotation
messages: Membrane

259536:PSYC RS08140
gene id: 259536:PSYC_RS08140
uniprot id: Q4FRD9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LolA family.
messages: Monomer.
messages: Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).
messages: Periplasm

259536:PSYC RS09775
gene id: 259536:PSYC_RS09775
uniprot id: Q4FQH1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

259536:PSYC RS02255
gene id: 259536:PSYC_RS02255
uniprot id: Q4FUL0
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

259536:PSYC RS02195
gene id: 259536:PSYC_RS02195
uniprot id: Q4FUM1
names: Similarity
messages: Belongs to the HsdR family.

259536:PSYC RS09305
gene id: 259536:PSYC_RS09305
uniprot id: Q4FQR3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

259536:PSYC RS06820
gene id: 259536:PSYC_RS06820
uniprot id: Q4FS43
names: Function
names: Similarity
messages: Belongs to the LpxK family.
messages: Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).

259536:PSYC RS10210
gene id: 259536:PSYC_RS10210
uniprot id: Q4FQ91
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

259536:PSYC RS05510
gene id: 259536:PSYC_RS05510
uniprot id: Q4FSV0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

259536:PSYC RS09750
gene id: 259536:PSYC_RS09750
uniprot id: Q4FQH6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.
messages: Membrane

259536:PSYC RS06925
gene id: 259536:PSYC_RS06925
uniprot id: Q4FS22
names: Subcellular Location Annotation
messages: Membrane

259536:PSYC RS08480
gene id: 259536:PSYC_RS08480
uniprot id: Q4FR76
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

259536:PSYC RS10350
gene id: 259536:PSYC_RS10350
uniprot id: Q4FQ63
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

259536:PSYC RS00700
gene id: 259536:PSYC_RS00700
uniprot id: Q4FVE7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

259536:PSYC RS05430
gene id: 259536:PSYC_RS05430
uniprot id: Q4FSW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

259536:PSYC RS03240
gene id: 259536:PSYC_RS03240
uniprot id: Q4FU30
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

259536:PSYC RS07950
gene id: 259536:PSYC_RS07950
uniprot id: Q4FRH4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
messages: Cytoplasm

259536:PSYC RS04770
gene id: 259536:PSYC_RS04770
uniprot id: Q4FT88
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.

259536:PSYC RS06350
gene id: 259536:PSYC_RS06350
uniprot id: Q4FSD6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide.

259536:PSYC RS05575
gene id: 259536:PSYC_RS05575
uniprot id: Q4FST7
names: Similarity
messages: Belongs to the sulfate adenylyltransferase family.

259536:PSYC RS02555
gene id: 259536:PSYC_RS02555
uniprot id: Q4FUF7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

259536:PSYC RS06105
gene id: 259536:PSYC_RS06105
uniprot id: Q4FSI4
names: Subcellular Location Annotation
messages: Membrane

259536:PSYC RS09785
gene id: 259536:PSYC_RS09785
uniprot id: Q4FQG9
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

259536:PSYC RS11165
gene id: 259536:PSYC_RS11165
uniprot id: Q4FPR5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

259536:PSYC RS07730
gene id: 259536:PSYC_RS07730
uniprot id: Q4FRL9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the OMP decarboxylase family. Type 1 subfamily.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
messages: Homodimer.

259536:PSYC RS10400
gene id: 259536:PSYC_RS10400
uniprot id: Q4FQ53
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

259536:PSYC RS07355
gene id: 259536:PSYC_RS07355
uniprot id: Q4FRU1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCF family. Uup subfamily.
messages: Cytoplasm
messages: Probably plays a role in ribosome assembly or function. May be involved in resolution of branched DNA intermediates that result from template switching in postreplication gaps. Binds DNA and has ATPase activity.

259536:PSYC RS07815
gene id: 259536:PSYC_RS07815
uniprot id: Q4FRK1
names: Subcellular Location Annotation
messages: Membrane

259536:PSYC RS05425
gene id: 259536:PSYC_RS05425
uniprot id: Q4FSW7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Monomer.
messages: Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.

259536:PSYC RS06640
gene id: 259536:PSYC_RS06640
uniprot id: Q4FS78
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

259536:PSYC RS08395
gene id: 259536:PSYC_RS08395
uniprot id: Q4FR92
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.

259536:PSYC RS08670
gene id: 259536:PSYC_RS08670
uniprot id: Q4FR38
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

259536:PSYC RS01645
gene id: 259536:PSYC_RS01645
uniprot id: Q4FUX1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

259536:PSYC RS05775
gene id: 259536:PSYC_RS05775
uniprot id: Q4FSP7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family.
messages: Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate.
messages: Homotetramer; dimer of dimers.
messages: Involved in the catabolism of short chain fatty acids (SCFA) via the 2-methylcitrate cycle (propionate degradation route). Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate via an alpha-carboxy-carbanion intermediate.

259536:PSYC RS03080
gene id: 259536:PSYC_RS03080
uniprot id: Q4FU62
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cell inner membrane
messages: In the C-terminal section; belongs to the complex I 49 kDa subunit family.
messages: In the N-terminal section; belongs to the complex I 30 kDa subunit family.
messages: NDH-1 is composed of 13 different subunits. Subunits NuoB, CD, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

259536:PSYC RS00240
gene id: 259536:PSYC_RS00240
uniprot id: Q4FVN8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptF/LptG family.
messages: Component of the lipopolysaccharide transport and assembly complex. The LptBFG transporter is composed of two ATP-binding proteins (LptB) and two transmembrane proteins (LptF and LptG).
messages: Membrane
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane.

259536:PSYC RS00335
gene id: 259536:PSYC_RS00335
uniprot id: Q4FVL9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

259536:PSYC RS06160
gene id: 259536:PSYC_RS06160
uniprot id: Q4FSH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EamA transporter family.
messages: Membrane

259536:PSYC RS07995
gene id: 259536:PSYC_RS07995
uniprot id: Q4FRG6
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. CmoM family.
messages: Catalyzes the methylation of 5-carboxymethoxyuridine (cmo5U) to form 5-methoxycarbonylmethoxyuridine (mcmo5U) at position 34 in tRNAs.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

259536:PSYC RS09700
gene id: 259536:PSYC_RS09700
uniprot id: Q4FQI6
names: Similarity
messages: Belongs to the glutamate synthase family.

259536:PSYC RS07320
gene id: 259536:PSYC_RS07320
uniprot id: Q4FRU8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

259536:PSYC RS01280
gene id: 259536:PSYC_RS01280
uniprot id: Q4FV42
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

259536:PSYC RS01815
gene id: 259536:PSYC_RS01815
uniprot id: Q4FUT8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

259536:PSYC RS10500
gene id: 259536:PSYC_RS10500
uniprot id: Q4FQ33
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell inner membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.

259536:PSYC RS01235
gene id: 259536:PSYC_RS01235
uniprot id: Q4FV50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PilY1 family.
messages: Fimbrium

259536:PSYC RS06150
gene id: 259536:PSYC_RS06150
uniprot id: Q4FSH6
names: Function
names: Similarity
messages: Belongs to the HPPK family.
messages: Catalyzes the transfer of pyrophosphate from adenosine triphosphate (ATP) to 6-hydroxymethyl-7,8-dihydropterin, an enzymatic step in folate biosynthesis pathway.

259536:PSYC RS10850
gene id: 259536:PSYC_RS10850
uniprot id: Q4FPW7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family. ParE type 1 subfamily.
messages: Cytoplasm
messages: Heterotetramer composed of ParC and ParE.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

259536:PSYC RS03120
gene id: 259536:PSYC_RS03120
uniprot id: Q4FU54
names: Subcellular Location Annotation
messages: Membrane

259536:PSYC RS09535
gene id: 259536:PSYC_RS09535
uniprot id: Q4FQL8
names: Similarity
messages: Belongs to the peptidase M16 family.

259536:PSYC RS07745
gene id: 259536:PSYC_RS07745
uniprot id: Q4FRL6
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS1 family.
messages: Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.

259536:PSYC RS07330
gene id: 259536:PSYC_RS07330
uniprot id: Q4FRU6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

259536:PSYC RS04735
gene id: 259536:PSYC_RS04735
uniprot id: Q4FT95
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

259536:PSYC RS07635
gene id: 259536:PSYC_RS07635
uniprot id: Q4FRN8
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

259536:PSYC RS10800
gene id: 259536:PSYC_RS10800
uniprot id: Q4FPX7
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

259536:PSYC RS04655
gene id: 259536:PSYC_RS04655
uniprot id: Q4FTB1
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

259536:PSYC RS00865
gene id: 259536:PSYC_RS00865
uniprot id: Q4FVB6
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

259536:PSYC RS03325
gene id: 259536:PSYC_RS03325
uniprot id: Q4FU15
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

259536:PSYC RS05555
gene id: 259536:PSYC_RS05555
uniprot id: Q4FSU1
names: Function
names: Similarity
messages: In the C-terminal section; belongs to the precorrin methyltransferase family.
messages: In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family.
messages: Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme.

259536:PSYC RS05855
gene id: 259536:PSYC_RS05855
uniprot id: Q4FSN1
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD.
messages: Belongs to the RecD family.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding.

259536:PSYC RS08225
gene id: 259536:PSYC_RS08225
uniprot id: Q4FRC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

259536:PSYC RS01375
gene id: 259536:PSYC_RS01375
uniprot id: Q4FV23
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Fur family.
messages: Cytoplasm
messages: Homodimer.

259536:PSYC RS04605
gene id: 259536:PSYC_RS04605
uniprot id: Q4FQ78
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

259536:PSYC RS00450
gene id: 259536:PSYC_RS00450
uniprot id: Q4FVJ7
names: Function
names: Similarity
messages: Belongs to the Fe(2+)-trafficking protein family.
messages: Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.

259536:PSYC RS02785
gene id: 259536:PSYC_RS02785
uniprot id: Q4FUB1
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

259536:PSYC RS10275
gene id: 259536:PSYC_RS10275
uniprot id: Q4FQ78
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

259536:PSYC RS04695
gene id: 259536:PSYC_RS04695
uniprot id: Q4FTA3
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

259536:PSYC RS10495
gene id: 259536:PSYC_RS10495
uniprot id: Q4FQ34
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase delta chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

259536:PSYC RS04960
gene id: 259536:PSYC_RS04960
uniprot id: Q4FT50
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArsB family.
messages: Cell membrane
messages: Involved in arsenical resistance. Thought to form the channel of an arsenite pump.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

259536:PSYC RS06595
gene id: 259536:PSYC_RS06595
uniprot id: Q4FS87
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

259536:PSYC RS08470
gene id: 259536:PSYC_RS08470
uniprot id: Q4FR77
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase T family.
messages: Binds two Mg(2+) per subunit. The active form of the enzyme binds two Mg(2+) ions in its active site. The first Mg(2+) forms only one salt bridge with the protein.
messages: Homodimer.
messages: Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis.

259536:PSYC RS09780
gene id: 259536:PSYC_RS09780
uniprot id: Q4FQH0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

259536:PSYC RS04470
gene id: 259536:PSYC_RS04470
uniprot id: Q4FTE7
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) per subunit.

259536:PSYC RS09610
gene id: 259536:PSYC_RS09610
uniprot id: Q4FQK3
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

259536:PSYC RS01030
gene id: 259536:PSYC_RS01030
uniprot id: Q4FV85
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.

259536:PSYC RS04565
gene id: 259536:PSYC_RS04565
uniprot id: Q4FTC8
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

259536:PSYC RS01760
gene id: 259536:PSYC_RS01760
uniprot id: Q4FUU9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell inner membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.

259536:PSYC RS09435
gene id: 259536:PSYC_RS09435
uniprot id: Q4FQN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

259536:PSYC RS10370
gene id: 259536:PSYC_RS10370
uniprot id: Q4FQ59
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

259536:PSYC RS06155
gene id: 259536:PSYC_RS06155
uniprot id: Q4FSH5
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

259536:PSYC RS00135
gene id: 259536:PSYC_RS00135
uniprot id: Q4FVQ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbC subfamily.
messages: Periplasm
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process.

259536:PSYC RS10550
gene id: 259536:PSYC_RS10550
uniprot id: Q4FQ23
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity).

259536:PSYC RS09225
gene id: 259536:PSYC_RS09225
uniprot id: Q4FQS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TPS (TC 1.B.20) family.
messages: Cell outer membrane
messages: Membrane

259536:PSYC RS00750
gene id: 259536:PSYC_RS00750
uniprot id: Q4FVD7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1C family.
messages: Periplasm

259536:PSYC RS09370
gene id: 259536:PSYC_RS09370
uniprot id: Q4FQQ0
names: Function
names: Similarity
messages: Belongs to the MinE family.
messages: Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.

259536:PSYC RS04940
gene id: 259536:PSYC_RS04940
uniprot id: Q4FT54
names: Function
names: Similarity
names: Subunit
messages: Belongs to the serine/threonine dehydratase family.
messages: Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
messages: Homotetramer.

259536:PSYC RS03745
gene id: 259536:PSYC_RS03745
uniprot id: Q4FTT1
names: Cofactor
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Binds 1 zinc ion per subunit. The zinc ion is important for the structural integrity of the protein.

259536:PSYC RS09915
gene id: 259536:PSYC_RS09915
uniprot id: Q4FQE4
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
messages: Part of the 50S ribosomal subunit.

259536:PSYC RS09845
gene id: 259536:PSYC_RS09845
uniprot id: Q4FQF8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

259536:PSYC RS07685
gene id: 259536:PSYC_RS07685
uniprot id: Q4FRM8
names: Similarity
messages: Belongs to the adrenodoxin/putidaredoxin family.

259536:PSYC RS01500
gene id: 259536:PSYC_RS01500
uniprot id: Q4FUZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiC family.
messages: Cytoplasm
messages: Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway.

259536:PSYC RS04195
gene id: 259536:PSYC_RS04195
uniprot id: Q4FTK0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

259536:PSYC RS06115
gene id: 259536:PSYC_RS06115
uniprot id: Q4FSI2
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

259536:PSYC RS06330
gene id: 259536:PSYC_RS06330
uniprot id: Q4FSE0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsrE/TusD family.
messages: Cytoplasm

259536:PSYC RS07910
gene id: 259536:PSYC_RS07910
uniprot id: Q4FRI2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

259536:PSYC RS03135
gene id: 259536:PSYC_RS03135
uniprot id: Q4FU51
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

259536:PSYC RS06740
gene id: 259536:PSYC_RS06740
uniprot id: Q4FS59
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

259536:PSYC RS05955
gene id: 259536:PSYC_RS05955
uniprot id: Q4FSL2
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MdcC family.
messages: Covalently binds the prosthetic group of malonate decarboxylase.
messages: Cytoplasm
messages: Subunit of malonate decarboxylase, it is an acyl carrier protein to which acetyl and malonyl thioester residues are bound via a 2'-(5''-phosphoribosyl)-3'-dephospho-CoA prosthetic group and turn over during the catalytic mechanism.

259536:PSYC RS00500
gene id: 259536:PSYC_RS00500
uniprot id: Q4FVI7
names: Similarity
messages: Belongs to the citrate synthase family.

259536:PSYC RS01775
gene id: 259536:PSYC_RS01775
uniprot id: Q4FUU6
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

259536:PSYC RS09455
gene id: 259536:PSYC_RS09455
uniprot id: Q4FQN3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmC/CycZ/HelC family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

259536:PSYC RS07780
gene id: 259536:PSYC_RS07780
uniprot id: Q4FRK9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

259536:PSYC RS10475
gene id: 259536:PSYC_RS10475
uniprot id: Q4FQ38
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

259536:PSYC RS08080
gene id: 259536:PSYC_RS08080
uniprot id: Q4FRF1
names: Function
names: Similarity
messages: Belongs to the CcmH/CycL/Ccl2/NrfF family.
messages: Possible subunit of a heme lyase.

259536:PSYC RS01545
gene id: 259536:PSYC_RS01545
uniprot id: Q4FUZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane

259536:PSYC RS06240
gene id: 259536:PSYC_RS06240
uniprot id: Q4FSF8
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

259536:PSYC RS04250
gene id: 259536:PSYC_RS04250
uniprot id: Q4FTJ0
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

259536:PSYC RS10365
gene id: 259536:PSYC_RS10365
uniprot id: Q4FQ60
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatB family.
messages: Cell inner membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

259536:PSYC RS08955
gene id: 259536:PSYC_RS08955
uniprot id: Q4FQY1
names: Similarity
messages: Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.

259536:PSYC RS02710
gene id: 259536:PSYC_RS02710
uniprot id: Q4FUC6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

259536:PSYC RS01695
gene id: 259536:PSYC_RS01695
uniprot id: Q4FUW1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
messages: Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.
messages: Cytoplasm
messages: Homodimer.

259536:PSYC RS08975
gene id: 259536:PSYC_RS08975
uniprot id: Q4FQX7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

259536:PSYC RS06880
gene id: 259536:PSYC_RS06880
uniprot id: Q4FS31
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Forms a 24-polypeptide structural core with octahedral symmetry.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

259536:PSYC RS04620
gene id: 259536:PSYC_RS04620
uniprot id: Q4FTB8
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

259536:PSYC RS06695
gene id: 259536:PSYC_RS06695
uniprot id: Q4FS67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XseA family.
messages: Cytoplasm

259536:PSYC RS00790
gene id: 259536:PSYC_RS00790
uniprot id: Q4FVC9
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

259536:PSYC RS07420
gene id: 259536:PSYC_RS07420
uniprot id: Q4FRS8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.

259536:PSYC RS10105
gene id: 259536:PSYC_RS10105
uniprot id: Q4FQA6
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

259536:PSYC RS09715
gene id: 259536:PSYC_RS09715
uniprot id: Q4FQI3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm

259536:PSYC RS06830
gene id: 259536:PSYC_RS06830
uniprot id: Q4FS41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

259536:PSYC RS06175
gene id: 259536:PSYC_RS06175
uniprot id: Q4FSH1
names: Function
names: Subcellular Location Annotation
messages: Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.
messages: Cytoplasm

259536:PSYC RS05020
gene id: 259536:PSYC_RS05020
uniprot id: Q4FT38
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

259536:PSYC RS11105
gene id: 259536:PSYC_RS11105
uniprot id: Q4FPS7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family. TsaC subfamily.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate.

259536:PSYC RS02770
gene id: 259536:PSYC_RS02770
uniprot id: Q4FUB4
names: Subcellular Location Annotation
messages: Cytoplasm

259536:PSYC RS08145
gene id: 259536:PSYC_RS08145
uniprot id: Q4FRD8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

259536:PSYC RS01285
gene id: 259536:PSYC_RS01285
uniprot id: Q4FV41
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

259536:PSYC RS01490
gene id: 259536:PSYC_RS01490
uniprot id: Q4FV01
names: Cofactor
names: Similarity
messages: Belongs to the monomeric-type IDH family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

259536:PSYC RS09665
gene id: 259536:PSYC_RS09665
uniprot id: Q4FQJ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.
messages: Cell membrane
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

259536:PSYC RS04165
gene id: 259536:PSYC_RS04165
uniprot id: Q4FTK6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

259536:PSYC RS10925
gene id: 259536:PSYC_RS10925
uniprot id: Q4FPW2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-3 family.
messages: Cytoplasm
messages: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
messages: Monomer.

259536:PSYC RS03385
gene id: 259536:PSYC_RS03385
uniprot id: Q4FU03
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

259536:PSYC RS01910
gene id: 259536:PSYC_RS01910
uniprot id: Q4FUS0
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

259536:PSYC RS07940
gene id: 259536:PSYC_RS07940
uniprot id: Q4FRH6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

259536:PSYC RS04990
gene id: 259536:PSYC_RS04990
uniprot id: Q4FT44
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

259536:PSYC RS02690
gene id: 259536:PSYC_RS02690
uniprot id: Q4FUD0
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

259536:PSYC RS10075
gene id: 259536:PSYC_RS10075
uniprot id: Q4FQB2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. CmoB family.
messages: Catalyzes carboxymethyl transfer from carboxy-S-adenosyl-L-methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5-carboxymethoxyuridine (cmo5U) at position 34 in tRNAs.
messages: Homotetramer.

259536:PSYC RS04895
gene id: 259536:PSYC_RS04895
uniprot id: Q4FT63
names: Subcellular Location Annotation
messages: Cytoplasm

259536:PSYC RS07040
gene id: 259536:PSYC_RS07040
uniprot id: Q4FS02
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
messages: Homodimer.

259536:PSYC RS04800
gene id: 259536:PSYC_RS04800
uniprot id: Q4FT82
names: Function
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate.
messages: Homotetramer.

259536:PSYC RS10240
gene id: 259536:PSYC_RS10240
uniprot id: Q4FQ85
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell inner membrane
messages: Membrane

259536:PSYC RS05525
gene id: 259536:PSYC_RS05525
uniprot id: Q4FSU7
names: Function
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.

259536:PSYC RS04335
gene id: 259536:PSYC_RS04335
uniprot id: Q4FTH2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

259536:PSYC RS09310
gene id: 259536:PSYC_RS09310
uniprot id: Q4FQR2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

259536:PSYC RS04290
gene id: 259536:PSYC_RS04290
uniprot id: Q4FTI2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

259536:PSYC RS02235
gene id: 259536:PSYC_RS02235
uniprot id: Q4FUL4
names: Similarity
messages: Belongs to the TrpF family.

259536:PSYC RS10720
gene id: 259536:PSYC_RS10720
uniprot id: Q4FPZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

259536:PSYC RS04875
gene id: 259536:PSYC_RS04875
uniprot id: Q4FT67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

259536:PSYC RS07405
gene id: 259536:PSYC_RS07405
uniprot id: Q4FRT1
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

259536:PSYC RS08570
gene id: 259536:PSYC_RS08570
uniprot id: Q4FR58
names: Cofactor
names: Function
messages: Binds 2 [4Fe-4S] clusters.
messages: Component of a complex that catalyzes the oxidation of glycolate to glyoxylate.

259536:PSYC RS02645
gene id: 259536:PSYC_RS02645
uniprot id: Q4FUD9
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

259536:PSYC RS03425
gene id: 259536:PSYC_RS03425
uniprot id: Q4FTZ5
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

259536:PSYC RS10540
gene id: 259536:PSYC_RS10540
uniprot id: Q4FQ25
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase class-III family.
messages: Binds 2 Fe(2+) ions per subunit.

259536:PSYC RS05730
gene id: 259536:PSYC_RS05730
uniprot id: Q4FSQ6
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

259536:PSYC RS10950
gene id: 259536:PSYC_RS10950
uniprot id: Q4FPV7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NqrA family.
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

259536:PSYC RS03845
gene id: 259536:PSYC_RS03845
uniprot id: Q4FTR8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

259536:PSYC RS00165
gene id: 259536:PSYC_RS00165
uniprot id: Q4FVQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

259536:PSYC RS02525
gene id: 259536:PSYC_RS02525
uniprot id: Q4FUG3
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

259536:PSYC RS02575
gene id: 259536:PSYC_RS02575
uniprot id: Q4FUF3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

259536:PSYC RS10010
gene id: 259536:PSYC_RS10010
uniprot id: Q4FQC5
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

259536:PSYC RS09005
gene id: 259536:PSYC_RS09005
uniprot id: Q4FQX1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
messages: Cytoplasm
messages: Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.

259536:PSYC RS11170
gene id: 259536:PSYC_RS11170
uniprot id: Q4FPR4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

259536:PSYC RS01205
gene id: 259536:PSYC_RS01205
uniprot id: Q4FV56
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phospholipase A1 family.
messages: Binds 1 Ca(2+) ion per monomer. In the dimeric form the Ca(2+) is bound by different amino acids with binding of each Ca(2+) shared with ligands coming from each monomer. The Ca(2+) ion may have a role in catalysis.
messages: Cell outer membrane
messages: Homodimer; dimerization is reversible, and the dimeric form is the active one.
messages: Hydrolysis of phosphatidylcholine with phospholipase A2 (EC 3.1.1.4) and phospholipase A1 (EC 3.1.1.32) activities.
messages: Membrane

259536:PSYC RS01835
gene id: 259536:PSYC_RS01835
uniprot id: Q4FUT4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

259536:PSYC RS03040
gene id: 259536:PSYC_RS03040
uniprot id: Q4FU69
names: Similarity
messages: Belongs to the ArsC family.

259536:PSYC RS00525
gene id: 259536:PSYC_RS00525
uniprot id: Q4FVI2
names: Function
names: Similarity
messages: Belongs to the alpha-ketoglutarate dehydrogenase family.
messages: E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

259536:PSYC RS09105
gene id: 259536:PSYC_RS09105
uniprot id: Q4FQV2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell inner membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Membrane

259536:PSYC RS09035
gene id: 259536:PSYC_RS09035
uniprot id: Q4FQW5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

259536:PSYC RS04450
gene id: 259536:PSYC_RS04450
uniprot id: Q4FTF0
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

259536:PSYC RS09805
gene id: 259536:PSYC_RS09805
uniprot id: Q4FQG6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

259536:PSYC RS11130
gene id: 259536:PSYC_RS11130
uniprot id: Q4FPS2
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

259536:PSYC RS01825
gene id: 259536:PSYC_RS01825
uniprot id: Q4FUT6
names: Subcellular Location Annotation
messages: Membrane

259536:PSYC RS05010
gene id: 259536:PSYC_RS05010
uniprot id: Q4FT40
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

259536:PSYC RS00375
gene id: 259536:PSYC_RS00375
uniprot id: Q4FVL3
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

259536:PSYC RS03170
gene id: 259536:PSYC_RS03170
uniprot id: Q4FU44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
messages: Cell membrane
messages: Membrane

259536:PSYC RS03070
gene id: 259536:PSYC_RS03070
uniprot id: Q4FU64
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

259536:PSYC RS10630
gene id: 259536:PSYC_RS10630
uniprot id: Q4FQ08
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

259536:PSYC RS07665
gene id: 259536:PSYC_RS07665
uniprot id: Q4FRN2
names: Function
names: Similarity
messages: A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters.
messages: Belongs to the NifU family.

259536:PSYC RS09890
gene id: 259536:PSYC_RS09890
uniprot id: Q4FQE9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NfuA family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is presumably bound at the interface of two monomers.
messages: Homodimer.
messages: Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins.

259536:PSYC RS05460
gene id: 259536:PSYC_RS05460
uniprot id: Q4FSW0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

259536:PSYC RS01400
gene id: 259536:PSYC_RS01400
uniprot id: Q4FV18
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

259536:PSYC RS07575
gene id: 259536:PSYC_RS07575
uniprot id: Q4FRQ0
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

259536:PSYC RS04010
gene id: 259536:PSYC_RS04010
uniprot id: Q4FTN7
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

259536:PSYC RS11150
gene id: 259536:PSYC_RS11150
uniprot id: Q4FPR8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.

259536:PSYC RS10610
gene id: 259536:PSYC_RS10610
uniprot id: Q4FQ12
names: Subcellular Location Annotation
messages: Membrane

259536:PSYC RS08525
gene id: 259536:PSYC_RS08525
uniprot id: Q4FR67
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the malate synthase family. GlcB subfamily.
messages: Cytoplasm
messages: Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

259536:PSYC RS09550
gene id: 259536:PSYC_RS09550
uniprot id: Q4FQL5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0324 family.
messages: Membrane

259536:PSYC RS02030
gene id: 259536:PSYC_RS02030
uniprot id: Q4FUQ2
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

259536:PSYC RS09820
gene id: 259536:PSYC_RS09820
uniprot id: Q4FQG3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

259536:PSYC RS03885
gene id: 259536:PSYC_RS03885
uniprot id: Q4FTR1
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

259536:PSYC RS10545
gene id: 259536:PSYC_RS10545
uniprot id: Q4FQ24
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DksA family.
messages: Cytoplasm
messages: Interacts directly with the RNA polymerase.
messages: Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression.

259536:PSYC RS06495
gene id: 259536:PSYC_RS06495
uniprot id: Q4FSA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

259536:PSYC RS07190
gene id: 259536:PSYC_RS07190
uniprot id: Q4FRX3
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.
messages: Homotetramer.

259536:PSYC RS00555
gene id: 259536:PSYC_RS00555
uniprot id: Q4FVH6
names: Similarity
messages: Belongs to the UDPGP type 2 family.

259536:PSYC RS05625
gene id: 259536:PSYC_RS05625
uniprot id: Q4FSS7
names: Subcellular Location Annotation
messages: Membrane

259536:PSYC RS02005
gene id: 259536:PSYC_RS02005
uniprot id: Q4FQG6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

259536:PSYC RS08045
gene id: 259536:PSYC_RS08045
uniprot id: Q4FRF8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-to-5' exoribonuclease specific for small oligoribonucleotides.
messages: Belongs to the oligoribonuclease family.
messages: Cytoplasm

259536:PSYC RS00295
gene id: 259536:PSYC_RS00295
uniprot id: Q4FVM7
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

259536:PSYC RS10740
gene id: 259536:PSYC_RS10740
uniprot id: Q4FPY9
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG).

259536:PSYC RS01330
gene id: 259536:PSYC_RS01330
uniprot id: Q4FV32
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase E/G family. RNase E subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per homotetramer.
messages: Cell inner membrane
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation. Within the RNA degradosome, RNase E assembles into a homotetramer formed by a dimer of dimers.
messages: Cytoplasm
messages: Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs.

259536:PSYC RS08835
gene id: 259536:PSYC_RS08835
uniprot id: Q4FR05
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell inner membrane

259536:PSYC RS00900
gene id: 259536:PSYC_RS00900
uniprot id: Q4FVB1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LolB family.
messages: Cell outer membrane
messages: Membrane
messages: Monomer.

259536:PSYC RS08005
gene id: 259536:PSYC_RS08005
uniprot id: Q4FRG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

259536:PSYC RS00355
gene id: 259536:PSYC_RS00355
uniprot id: Q4FVL7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

259536:PSYC RS02630
gene id: 259536:PSYC_RS02630
uniprot id: Q4FUE2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

259536:PSYC RS07870
gene id: 259536:PSYC_RS07870
uniprot id: Q4FRJ0
names: Domain
names: Function
names: Subcellular Location Annotation
messages: Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation.
messages: Periplasm
messages: The PPIase activity resides only in the second parvulin domain. The N-terminal region and the C-terminal tail are necessary and sufficient for the chaperone activity of SurA. The PPIase activity is dispensable for SurA to function as a chaperone. The N-terminal region and the C-terminal tail are also required for porin recognition.

259536:PSYC RS05755
gene id: 259536:PSYC_RS05755
uniprot id: Q4FSQ1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

259536:PSYC RS08625
gene id: 259536:PSYC_RS08625
uniprot id: Q4FR48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

259536:PSYC RS08965
gene id: 259536:PSYC_RS08965
uniprot id: Q4FQX9
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.

259536:PSYC RS07690
gene id: 259536:PSYC_RS07690
uniprot id: Q4FRM7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

259536:PSYC RS10525
gene id: 259536:PSYC_RS10525
uniprot id: Q4FQ28
names: Similarity
messages: Belongs to the Fur family.

259536:PSYC RS02650
gene id: 259536:PSYC_RS02650
uniprot id: Q4FUD8
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

259536:PSYC RS00875
gene id: 259536:PSYC_RS00875
uniprot id: Q4FVB4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

259536:PSYC RS06940
gene id: 259536:PSYC_RS06940
uniprot id: Q4FS19
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

259536:PSYC RS10935
gene id: 259536:PSYC_RS10935
uniprot id: Q4FPW0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

259536:PSYC RS10830
gene id: 259536:PSYC_RS10830
uniprot id: Q4FPX1
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

259536:PSYC RS00585
gene id: 259536:PSYC_RS00585
uniprot id: Q4FVH0
names: Function
names: Similarity
messages: Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control.
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

259536:PSYC RS09140
gene id: 259536:PSYC_RS09140
uniprot id: Q4FQU5
names: Similarity
messages: Belongs to the transglycosylase Slt family.

259536:PSYC RS06095
gene id: 259536:PSYC_RS06095
uniprot id: Q4FSI6
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

259536:PSYC RS10640
gene id: 259536:PSYC_RS10640
uniprot id: Q4FQ06
names: Subcellular Location Annotation
messages: Membrane

259536:PSYC RS06410
gene id: 259536:PSYC_RS06410
uniprot id: Q4FSC4
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

259536:PSYC RS04980
gene id: 259536:PSYC_RS04980
uniprot id: Q4FT46
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins.

259536:PSYC RS10960
gene id: 259536:PSYC_RS10960
uniprot id: Q4FPV5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrC family.
messages: Cell inner membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

259536:PSYC RS07060
gene id: 259536:PSYC_RS07060
uniprot id: Q4FRZ8
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

259536:PSYC RS01025
gene id: 259536:PSYC_RS01025
uniprot id: Q4FV86
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

259536:PSYC RS05045
gene id: 259536:PSYC_RS05045
uniprot id: Q4FT33
names: Similarity
messages: Belongs to the TrpC family.

259536:PSYC RS10335
gene id: 259536:PSYC_RS10335
uniprot id: Q4FQ66
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

259536:PSYC RS00320
gene id: 259536:PSYC_RS00320
uniprot id: Q4FVM2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A24 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Plays an essential role in type IV pili and type II pseudopili formation by proteolytically removing the leader sequence from substrate proteins and subsequently monomethylating the alpha-amino group of the newly exposed N-terminal phenylalanine.

259536:PSYC RS06375
gene id: 259536:PSYC_RS06375
uniprot id: Q4FSD1
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

259536:PSYC RS00960
gene id: 259536:PSYC_RS00960
uniprot id: Q4FVA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

259536:PSYC RS09960
gene id: 259536:PSYC_RS09960
uniprot id: Q4FQD5
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type I sub-subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The autoendoproteolytic cleavage occurs by a canonical serine protease mechanism, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain. During this reaction, the Ser that is part of the protease active site of the proenzyme becomes the pyruvoyl prosthetic group, which constitutes an essential element of the active site of the mature decarboxylase.

259536:PSYC RS08615
gene id: 259536:PSYC_RS08615
uniprot id: Q4FR50
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

259536:PSYC RS07215
gene id: 259536:PSYC_RS07215
uniprot id: Q4FRW8
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.

259536:PSYC RS02655
gene id: 259536:PSYC_RS02655
uniprot id: Q4FUD7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

259536:PSYC RS01615
gene id: 259536:PSYC_RS01615
uniprot id: Q4FUX6
names: Similarity
messages: Belongs to the HMG-CoA lyase family.

259536:PSYC RS06600
gene id: 259536:PSYC_RS06600
uniprot id: Q4FS86
names: Similarity
messages: Belongs to the transglycosylase Slt family.

259536:PSYC RS03095
gene id: 259536:PSYC_RS03095
uniprot id: Q4FU59
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the complex I 75 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Composed of 13 different subunits. Subunits NuoCD, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

259536:PSYC RS00430
gene id: 259536:PSYC_RS00430
uniprot id: Q4FVK1
names: Subcellular Location Annotation
messages: Membrane

259536:PSYC RS07360
gene id: 259536:PSYC_RS07360
uniprot id: Q4FRU0
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Rieske iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
messages: Membrane
messages: The Rieske protein is a high potential 2Fe-2S protein.
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

259536:PSYC RS00825
gene id: 259536:PSYC_RS00825
uniprot id: Q4FVC2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

259536:PSYC RS07195
gene id: 259536:PSYC_RS07195
uniprot id: Q4FRX2
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

259536:PSYC RS00685
gene id: 259536:PSYC_RS00685
uniprot id: Q4FVF0
names: Similarity
messages: Belongs to the GPAT/DAPAT family.

259536:PSYC RS00145
gene id: 259536:PSYC_RS00145
uniprot id: Q4FVQ7
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

259536:PSYC RS07765
gene id: 259536:PSYC_RS07765
uniprot id: Q4FRL2
names: Similarity
messages: Belongs to the ClpA/ClpB family.

259536:PSYC RS01725
gene id: 259536:PSYC_RS01725
uniprot id: Q4FUV6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

259536:PSYC RS04140
gene id: 259536:PSYC_RS04140
uniprot id: Q4FTL1
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

259536:PSYC RS01355
gene id: 259536:PSYC_RS01355
uniprot id: Q4FV27
names: PTM
messages: Binds 2 heme c groups covalently per subunit.

259536:PSYC RS00020
gene id: 259536:PSYC_RS00020
uniprot id: Q4FVT2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

259536:PSYC RS08800
gene id: 259536:PSYC_RS08800
uniprot id: Q4FR12
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YciB family.
messages: Cell inner membrane
messages: Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis.

259536:PSYC RS08405
gene id: 259536:PSYC_RS08405
uniprot id: Q4FR90
names: Similarity
messages: Belongs to the Dps family.

259536:PSYC RS00835
gene id: 259536:PSYC_RS00835
uniprot id: Q4FVC0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

259536:PSYC RS07530
gene id: 259536:PSYC_RS07530
uniprot id: Q4FTE1
names: Similarity
messages: Belongs to the transposase 8 family.

259536:PSYC RS08775
gene id: 259536:PSYC_RS08775
uniprot id: Q4FR17
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

259536:PSYC RS02725
gene id: 259536:PSYC_RS02725
uniprot id: Q4FUC3
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

259536:PSYC RS02545
gene id: 259536:PSYC_RS02545
uniprot id: Q4FUF9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

259536:PSYC RS03105
gene id: 259536:PSYC_RS03105
uniprot id: Q4FU57
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

259536:PSYC RS09190
gene id: 259536:PSYC_RS09190
uniprot id: Q4FQT5
names: Subcellular Location Annotation
messages: Membrane

259536:PSYC RS09590
gene id: 259536:PSYC_RS09590
uniprot id: Q4FQK7
names: Similarity
messages: Belongs to the UPF0145 family.

259536:PSYC RS10835
gene id: 259536:PSYC_RS10835
uniprot id: Q4FPX0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Cell inner membrane
messages: Homoheptamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.

259536:PSYC RS04355
gene id: 259536:PSYC_RS04355
uniprot id: Q4FTG8
names: Similarity
messages: Belongs to the peptidase S66 family.

259536:PSYC RS02245
gene id: 259536:PSYC_RS02245
uniprot id: Q4FUL2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

259536:PSYC RS03395
gene id: 259536:PSYC_RS03395
uniprot id: Q4FU01
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

259536:PSYC RS05640
gene id: 259536:PSYC_RS05640
uniprot id: Q4FSS4
names: Similarity
messages: Belongs to the DEAD box helicase family.

259536:PSYC RS01105
gene id: 259536:PSYC_RS01105
uniprot id: Q4FV71
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

259536:PSYC RS00935
gene id: 259536:PSYC_RS00935
uniprot id: Q4FVA4
names: Similarity
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

259536:PSYC RS02920
gene id: 259536:PSYC_RS02920
uniprot id: Q4FU86
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M20A family. DapE subfamily.
messages: Binds 2 Zn(2+) or Co(2+) ions per subunit.
messages: Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
messages: Homodimer.

259536:PSYC RS00160
gene id: 259536:PSYC_RS00160
uniprot id: Q4FVQ4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

259536:PSYC RS06935
gene id: 259536:PSYC_RS06935
uniprot id: Q4FS20
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

259536:PSYC RS06420
gene id: 259536:PSYC_RS06420
uniprot id: Q4FSC2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

259536:PSYC RS10620
gene id: 259536:PSYC_RS10620
uniprot id: Q4FQ10
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell inner membrane

259536:PSYC RS06920
gene id: 259536:PSYC_RS06920
uniprot id: Q4FS23
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

259536:PSYC RS05895
gene id: 259536:PSYC_RS05895
uniprot id: Q4FSM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

259536:PSYC RS10135
gene id: 259536:PSYC_RS10135
uniprot id: Q4FQA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

259536:PSYC RS03735
gene id: 259536:PSYC_RS03735
uniprot id: Q4FTT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane

259536:PSYC RS04095
gene id: 259536:PSYC_RS04095
uniprot id: Q4FTM0
names: Subcellular Location Annotation
messages: Membrane

259536:PSYC RS10155
gene id: 259536:PSYC_RS10155
uniprot id: Q4FQ97
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

259536:PSYC RS00680
gene id: 259536:PSYC_RS00680
uniprot id: Q4FVF1
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

259536:PSYC RS10295
gene id: 259536:PSYC_RS10295
uniprot id: Q4FQ74
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

259536:PSYC RS04825
gene id: 259536:PSYC_RS04825
uniprot id: Q4FT77
names: Function
names: Similarity
messages: Belongs to the RlpA family.
messages: Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.

259536:PSYC RS02600
gene id: 259536:PSYC_RS02600
uniprot id: Q4FUE8
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

259536:PSYC RS04625
gene id: 259536:PSYC_RS04625
uniprot id: Q4FTB7
names: Similarity
messages: Belongs to the tRNA methyltransferase O family.

259536:PSYC RS10805
gene id: 259536:PSYC_RS10805
uniprot id: Q4FPX6
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.

259536:PSYC RS01395
gene id: 259536:PSYC_RS01395
uniprot id: Q4FV19
names: Subcellular Location Annotation
messages: Membrane

259536:PSYC RS06530
gene id: 259536:PSYC_RS06530
uniprot id: Q4FSA0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamD family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

259536:PSYC RS03400
gene id: 259536:PSYC_RS03400
uniprot id: Q4FU00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the etk/wzc family.
messages: Cell inner membrane
messages: Membrane

259536:PSYC RS04310
gene id: 259536:PSYC_RS04310
uniprot id: Q4FTH7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

259536:PSYC RS06360
gene id: 259536:PSYC_RS06360
uniprot id: Q4FSD4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

259536:PSYC RS03210
gene id: 259536:PSYC_RS03210
uniprot id: Q4FU36
names: Function
names: Similarity
messages: Belongs to the MoaB/Mog family.
messages: May be involved in the biosynthesis of molybdopterin.

259536:PSYC RS06815
gene id: 259536:PSYC_RS06815
uniprot id: Q4FS44
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
messages: Belongs to the KdsB family.
messages: Cytoplasm

259536:PSYC RS02565
gene id: 259536:PSYC_RS02565
uniprot id: Q4FUF5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

259536:PSYC RS05780
gene id: 259536:PSYC_RS05780
uniprot id: Q4FSP6
names: Similarity
messages: Belongs to the citrate synthase family.

259536:PSYC RS01525
gene id: 259536:PSYC_RS01525
uniprot id: Q4FUZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

259536:PSYC RS08390
gene id: 259536:PSYC_RS08390
uniprot id: Q4FR93
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Homodimer.

259536:PSYC RS10560
gene id: 259536:PSYC_RS10560
uniprot id: Q4FQ21
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

259536:PSYC RS00480
gene id: 259536:PSYC_RS00480
uniprot id: Q4FVJ1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

259536:PSYC RS09770
gene id: 259536:PSYC_RS09770
uniprot id: Q4FQH2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

259536:PSYC RS04570
gene id: 259536:PSYC_RS04570
uniprot id: Q4FTC7
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

259536:PSYC RS00765
gene id: 259536:PSYC_RS00765
uniprot id: Q4FVD4
names: Similarity
messages: Belongs to the SAICAR synthetase family.

259536:PSYC RS09505
gene id: 259536:PSYC_RS09505
uniprot id: Q4FQM3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

259536:PSYC RS03420
gene id: 259536:PSYC_RS03420
uniprot id: Q4FTZ6
names: Similarity
messages: Belongs to the polysaccharide synthase family.

259536:PSYC RS10980
gene id: 259536:PSYC_RS10980
uniprot id: Q4FPV1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ApbE family.
messages: Cell inner membrane
messages: Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.
messages: Magnesium. Can also use manganese.

259536:PSYC RS04045
gene id: 259536:PSYC_RS04045
uniprot id: Q4FTN0
names: Similarity
messages: Belongs to the CcoP / FixP family.

259536:PSYC RS08705
gene id: 259536:PSYC_RS08705
uniprot id: Q4FR31
names: Similarity
messages: Belongs to the radical SAM superfamily. KamA family.

259536:PSYC RS08520
gene id: 259536:PSYC_RS08520
uniprot id: Q4FR68
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

259536:PSYC RS09180
gene id: 259536:PSYC_RS09180
uniprot id: Q4FQT7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

259536:PSYC RS10535
gene id: 259536:PSYC_RS10535
uniprot id: Q4FQ26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

259536:PSYC RS01035
gene id: 259536:PSYC_RS01035
uniprot id: Q4FV84
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

259536:PSYC RS08600
gene id: 259536:PSYC_RS08600
uniprot id: Q4FR52
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

259536:PSYC RS00445
gene id: 259536:PSYC_RS00445
uniprot id: Q4FVJ8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
messages: Homodimer.

259536:PSYC RS02640
gene id: 259536:PSYC_RS02640
uniprot id: Q4FUE0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

259536:PSYC RS05515
gene id: 259536:PSYC_RS05515
uniprot id: Q4FSU9
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

259536:PSYC RS03110
gene id: 259536:PSYC_RS03110
uniprot id: Q4FU56
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: Composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

259536:PSYC RS05505
gene id: 259536:PSYC_RS05505
uniprot id: Q4FSV1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

259536:PSYC RS01810
gene id: 259536:PSYC_RS01810
uniprot id: Q4FUT9
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

259536:PSYC RS03130
gene id: 259536:PSYC_RS03130
uniprot id: Q4FU52
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

259536:PSYC RS03480
gene id: 259536:PSYC_RS03480
uniprot id: Q4FTY4
names: Similarity
messages: Belongs to the asparagine synthetase family.

259536:PSYC RS08940
gene id: 259536:PSYC_RS08940
uniprot id: Q4FQY4
names: Similarity
messages: Belongs to the RutC family.

259536:PSYC RS06675
gene id: 259536:PSYC_RS06675
uniprot id: Q4FS71
names: Cofactor
names: Similarity
messages: Belongs to the nitroreductase family.
messages: Binds 1 FMN per subunit.

259536:PSYC RS11060
gene id: 259536:PSYC_RS11060
uniprot id: Q4FPT6
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

259536:PSYC RS00370
gene id: 259536:PSYC_RS00370
uniprot id: Q4FVL4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

259536:PSYC RS00215
gene id: 259536:PSYC_RS00215
uniprot id: Q4FVP3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Cell inner membrane
messages: Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system).

259536:PSYC RS00440
gene id: 259536:PSYC_RS00440
uniprot id: Q4FVJ9
names: Similarity
messages: Belongs to the class I fructose-bisphosphate aldolase family.

259536:PSYC RS07645
gene id: 259536:PSYC_RS07645
uniprot id: Q4FRN6
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

259536:PSYC RS04795
gene id: 259536:PSYC_RS04795
uniprot id: Q4FT83
names: Similarity
messages: Belongs to the SIS family. GutQ/KpsF subfamily.

259536:PSYC RS06565
gene id: 259536:PSYC_RS06565
uniprot id: Q4FS93
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

259536:PSYC RS06010
gene id: 259536:PSYC_RS06010
uniprot id: Q4FSK3
names: Similarity
messages: Belongs to the universal stress protein A family.

259536:PSYC RS08865
gene id: 259536:PSYC_RS08865
uniprot id: Q4FQZ9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

259536:PSYC RS03575
gene id: 259536:PSYC_RS03575
uniprot id: Q4FTW5
names: Similarity
messages: Belongs to the YfgM family.

259536:PSYC RS07945
gene id: 259536:PSYC_RS07945
uniprot id: Q4FRH5
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.

259536:PSYC RS09965
gene id: 259536:PSYC_RS09965
uniprot id: Q4FQD4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PstS family.
messages: Part of the ABC transporter complex PstSACB involved in phosphate import.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

259536:PSYC RS03065
gene id: 259536:PSYC_RS03065
uniprot id: Q4FU65
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. UvrD subfamily.
messages: Homodimer.
messages: Rep helicase is a single-stranded DNA-dependent ATPase involved in DNA replication; it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction.

259536:PSYC RS05740
gene id: 259536:PSYC_RS05740
uniprot id: Q4FSQ4
names: Similarity
messages: Belongs to the D-glutamate cyclase family.

259536:PSYC RS09060
gene id: 259536:PSYC_RS09060
uniprot id: Q4FQW0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

259536:PSYC RS09955
gene id: 259536:PSYC_RS09955
uniprot id: Q4FQD6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

259536:PSYC RS07920
gene id: 259536:PSYC_RS07920
uniprot id: Q4FRI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

259536:PSYC RS06850
gene id: 259536:PSYC_RS06850
uniprot id: Q4FS37
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.

259536:PSYC RS08425
gene id: 259536:PSYC_RS08425
uniprot id: Q4FR86
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

259536:PSYC RS03890
gene id: 259536:PSYC_RS03890
uniprot id: Q4FTR0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

259536:PSYC RS03300
gene id: 259536:PSYC_RS03300
uniprot id: Q4FU20
names: Similarity
messages: Belongs to the UbiH/COQ6 family.

259536:PSYC RS04970
gene id: 259536:PSYC_RS04970
uniprot id: Q4FT48
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm
messages: Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.

259536:PSYC RS05590
gene id: 259536:PSYC_RS05590
uniprot id: Q4FST4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the ABC transporter complex (TC 3.A.1.6.1) involved in sulfate/thiosulfate import.
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

259536:PSYC RS06670
gene id: 259536:PSYC_RS06670
uniprot id: Q4FS72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

259536:PSYC RS01000
gene id: 259536:PSYC_RS01000
uniprot id: Q4FV91
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein L14 (rplN).

259536:PSYC RS07300
gene id: 259536:PSYC_RS07300
uniprot id: Q4FRV2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

259536:PSYC RS03060
gene id: 259536:PSYC_RS03060
uniprot id: Q4FU66
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

259536:PSYC RS03685
gene id: 259536:PSYC_RS03685
uniprot id: Q4FTU3
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

259536:PSYC RS02760
gene id: 259536:PSYC_RS02760
uniprot id: Q4FUB6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.

259536:PSYC RS10195
gene id: 259536:PSYC_RS10195
uniprot id: Q4FQ94
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

259536:PSYC RS03935
gene id: 259536:PSYC_RS03935
uniprot id: Q4FTQ2
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

259536:PSYC RS03055
gene id: 259536:PSYC_RS03055
uniprot id: Q4FU67
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

259536:PSYC RS09905
gene id: 259536:PSYC_RS09905
uniprot id: Q4FQE6
names: Similarity
messages: Belongs to the NAPRTase family.

259536:PSYC RS04000
gene id: 259536:PSYC_RS04000
uniprot id: Q4FTN9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RlmKL family.
messages: Cytoplasm
messages: Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA.

259536:PSYC RS09950
gene id: 259536:PSYC_RS09950
uniprot id: Q4FQD7
names: Function
messages: This protein is a positive regulator for the phosphate regulon. Transcription of this operon is positively regulated by PhoB and PhoR when phosphate is limited.

259536:PSYC RS04995
gene id: 259536:PSYC_RS04995
uniprot id: Q4FT43
names: Function
names: Similarity
messages: Belongs to the Ap4A hydrolase family.
messages: Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP.

259536:PSYC RS00710
gene id: 259536:PSYC_RS00710
uniprot id: Q4FVE5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).

259536:PSYC RS02535
gene id: 259536:PSYC_RS02535
uniprot id: Q4FUG1
names: Function
names: Similarity
messages: Belongs to the MreC family.
messages: Involved in formation and maintenance of cell shape.

259536:PSYC RS01460
gene id: 259536:PSYC_RS01460
uniprot id: Q4FV07
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 3 family. NagZ subfamily.
messages: Cytoplasm
messages: Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides.

259536:PSYC RS02220
gene id: 259536:PSYC_RS02220
uniprot id: Q4FUL7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family. QueF type 2 subfamily.
messages: Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
messages: Cytoplasm
messages: Homodimer.

259536:PSYC RS03650
gene id: 259536:PSYC_RS03650
uniprot id: Q4FTV0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RuvC family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.

259536:PSYC RS02795
gene id: 259536:PSYC_RS02795
uniprot id: Q4FTE1
names: Similarity
messages: Belongs to the transposase 8 family.

259536:PSYC RS01620
gene id: 259536:PSYC_RS01620
uniprot id: Q4FUX5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

259536:PSYC RS00405
gene id: 259536:PSYC_RS00405
uniprot id: Q4FVK6
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

259536:PSYC RS03200
gene id: 259536:PSYC_RS03200
uniprot id: Q4FU38
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

259536:PSYC RS04060
gene id: 259536:PSYC_RS04060
uniprot id: Q4FTM7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Binds 1 copper ion per subunit, denoted as copper B.
messages: Binds 2 heme groups per subunit, denoted as high- and low-spin.
messages: Membrane

259536:PSYC RS03285
gene id: 259536:PSYC_RS03285
uniprot id: Q4FU23
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

259536:PSYC RS08420
gene id: 259536:PSYC_RS08420
uniprot id: Q4FR87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

259536:PSYC RS03495
gene id: 259536:PSYC_RS03495
uniprot id: Q4FTY1
names: Similarity
messages: Belongs to the asparagine synthetase family.

259536:PSYC RS08315
gene id: 259536:PSYC_RS08315
uniprot id: Q4FRA6
names: Similarity
messages: Belongs to the ACC deaminase/D-cysteine desulfhydrase family.

259536:PSYC RS00740
gene id: 259536:PSYC_RS00740
uniprot id: Q4FVD9
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

259536:PSYC RS04275
gene id: 259536:PSYC_RS04275
uniprot id: Q4FTI5
names: Function
names: Similarity
messages: Belongs to the nucleoside phosphorylase PpnP family.
messages: Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions.

259536:PSYC RS07045
gene id: 259536:PSYC_RS07045
uniprot id: Q4FS01
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

259536:PSYC RS10065
gene id: 259536:PSYC_RS10065
uniprot id: Q4FQB4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

259536:PSYC RS06415
gene id: 259536:PSYC_RS06415
uniprot id: Q4FSC3
names: Subcellular Location Annotation
messages: Membrane

259536:PSYC RS02520
gene id: 259536:PSYC_RS02520
uniprot id: Q4FUG4
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

259536:PSYC RS04220
gene id: 259536:PSYC_RS04220
uniprot id: Q4FTJ6
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

259536:PSYC RS00735
gene id: 259536:PSYC_RS00735
uniprot id: Q4FVE0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase MltG family.
messages: Cell inner membrane
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

259536:PSYC RS07890
gene id: 259536:PSYC_RS07890
uniprot id: Q4FRI6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

259536:PSYC RS07055
gene id: 259536:PSYC_RS07055
uniprot id: Q4FRZ9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

259536:PSYC RS00365
gene id: 259536:PSYC_RS00365
uniprot id: Q4FVL5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

259536:PSYC RS06545
gene id: 259536:PSYC_RS06545
uniprot id: Q4FS97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0187 family.
messages: Membrane

259536:PSYC RS09985
gene id: 259536:PSYC_RS09985
uniprot id: Q4FQD0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

259536:PSYC RS02065
gene id: 259536:PSYC_RS02065
uniprot id: Q4FUP5
names: Activity Regulation
names: Domain
names: Function
names: Similarity
messages: Belongs to the GlnD family.
messages: Has four distinct domains: an N-terminal nucleotidyltransferase (NT) domain responsible for UTase activity, a central HD domain that encodes UR activity, and two C-terminal ACT domains that seem to have a role in glutamine sensing.
messages: Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism.
messages: Uridylyltransferase (UTase) activity is inhibited by glutamine, while glutamine activates uridylyl-removing (UR) activity.

259536:PSYC RS02515
gene id: 259536:PSYC_RS02515
uniprot id: Q4FUG5
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

259536:PSYC RS10050
gene id: 259536:PSYC_RS10050
uniprot id: Q4FQB7
names: Disruption Phenotype
names: Function
names: PTM
names: Subcellular Location Annotation
names: Subunit
messages: Binds 2 heme c groups covalently per subunit.
messages: Catalyzes the oxidation of 2 molecules of thiosulfate to tetrathionate.
messages: Cells are unable to produce tetrathionate from thiosulfate.
messages: Monomer.
messages: Periplasm

259536:PSYC RS10230
gene id: 259536:PSYC_RS10230
uniprot id: Q4FQ87
names: Similarity
messages: Belongs to the peptidase M24B family.