2571748:FAZ98 RS08995
gene id: 2571748:FAZ98_RS08995
uniprot id: A0A7Z2GHE6
names: Function
messages: This protein is a positive regulator for the phosphate regulon. Transcription of this operon is positively regulated by PhoB and PhoR when phosphate is limited.

2571748:FAZ98 RS12850
gene id: 2571748:FAZ98_RS12850
uniprot id: A0A7Z2GJD4
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

2571748:FAZ98 RS09335
gene id: 2571748:FAZ98_RS09335
uniprot id: A0A7Z2GHK6
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

2571748:FAZ98 RS09000
gene id: 2571748:FAZ98_RS09000
uniprot id: A0A7Z2GHM6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

2571748:FAZ98 RS12830
gene id: 2571748:FAZ98_RS12830
uniprot id: A0A7Z2JF98
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

2571748:FAZ98 RS07405
gene id: 2571748:FAZ98_RS07405
uniprot id: A0A7Z2GK22
names: Similarity
messages: Belongs to the thioredoxin family.

2571748:FAZ98 RS12905
gene id: 2571748:FAZ98_RS12905
uniprot id: A0A7Z2JFA8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

2571748:FAZ98 RS12400
gene id: 2571748:FAZ98_RS12400
uniprot id: A0A7Z2GIL9
names: Subcellular Location Annotation
messages: Cytoplasm

2571748:FAZ98 RS12910
gene id: 2571748:FAZ98_RS12910
uniprot id: A0A7Z2JER4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

2571748:FAZ98 RS13950
gene id: 2571748:FAZ98_RS13950
uniprot id: A0A7Z2GJA3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

2571748:FAZ98 RS01140
gene id: 2571748:FAZ98_RS01140
uniprot id: A0A7Z2GFA2
names: Similarity
messages: Belongs to the P(II) protein family.

2571748:FAZ98 RS07430
gene id: 2571748:FAZ98_RS07430
uniprot id: A0A7Z2GHL6
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
messages: Part of the 50S ribosomal subunit.

2571748:FAZ98 RS12940
gene id: 2571748:FAZ98_RS12940
uniprot id: A0A7Z2GIY2
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: Methylated by PrmB.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

2571748:FAZ98 RS05100
gene id: 2571748:FAZ98_RS05100
uniprot id: A0A7Z2GGU7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

2571748:FAZ98 RS12900
gene id: 2571748:FAZ98_RS12900
uniprot id: A0A7Z2JGV3
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

2571748:FAZ98 RS09360
gene id: 2571748:FAZ98_RS09360
uniprot id: A0A7Z2GHI6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

2571748:FAZ98 RS07410
gene id: 2571748:FAZ98_RS07410
uniprot id: A0A7Z2GGV2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2571748:FAZ98 RS10040
gene id: 2571748:FAZ98_RS10040
uniprot id: A0A7Z2GHR3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

2571748:FAZ98 RS12855
gene id: 2571748:FAZ98_RS12855
uniprot id: A0A7Z2GIX0
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

2571748:FAZ98 RS12870
gene id: 2571748:FAZ98_RS12870
uniprot id: A0A7Z2GJD6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

2571748:FAZ98 RS09725
gene id: 2571748:FAZ98_RS09725
uniprot id: A0A7Z2JGA9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2571748:FAZ98 RS10690
gene id: 2571748:FAZ98_RS10690
uniprot id: A0A7Z2GI33
names: Subcellular Location Annotation
messages: Cytoplasm

2571748:FAZ98 RS12960
gene id: 2571748:FAZ98_RS12960
uniprot id: A0A7Z2GIU3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

2571748:FAZ98 RS13025
gene id: 2571748:FAZ98_RS13025
uniprot id: A0A7Z2GIT4
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

2571748:FAZ98 RS01970
gene id: 2571748:FAZ98_RS01970
uniprot id: A0A7Z2GFA0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

2571748:FAZ98 RS12935
gene id: 2571748:FAZ98_RS12935
uniprot id: A0A7Z2GIS1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

2571748:FAZ98 RS10600
gene id: 2571748:FAZ98_RS10600
uniprot id: A0A7Z2GI23
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

2571748:FAZ98 RS12875
gene id: 2571748:FAZ98_RS12875
uniprot id: A0A7Z2GIS3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

2571748:FAZ98 RS01455
gene id: 2571748:FAZ98_RS01455
uniprot id: A0A7Z2GET0
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HPrK/P family.
messages: Both phosphorylation and phosphorolysis are carried out by the same active site and suggest a common mechanism for both reactions.
messages: Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr).
messages: Homohexamer.
messages: The Walker A ATP-binding motif also binds Pi and PPi.

2571748:FAZ98 RS03825
gene id: 2571748:FAZ98_RS03825
uniprot id: A0A7Z2GFP1
names: Cofactor
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Binds 1 Fe(3+) ion per subunit.

2571748:FAZ98 RS12805
gene id: 2571748:FAZ98_RS12805
uniprot id: A0A7Z2GIP8
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

2571748:FAZ98 RS04415
gene id: 2571748:FAZ98_RS04415
uniprot id: A0A7Z2JDX0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

2571748:FAZ98 RS12480
gene id: 2571748:FAZ98_RS12480
uniprot id: A0A7Z2GIM9
names: Similarity
messages: Belongs to the GST superfamily. HSP26 family.

2571748:FAZ98 RS12820
gene id: 2571748:FAZ98_RS12820
uniprot id: A0A7Z2GJF3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

2571748:FAZ98 RS12930
gene id: 2571748:FAZ98_RS12930
uniprot id: A0A7Z2GIY1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

2571748:FAZ98 RS13745
gene id: 2571748:FAZ98_RS13745
uniprot id: A0A7Z2GJ01
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

2571748:FAZ98 RS07090
gene id: 2571748:FAZ98_RS07090
uniprot id: A0A7Z2GGR9
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

2571748:FAZ98 RS00205
gene id: 2571748:FAZ98_RS00205
uniprot id: A0A7Z2GEC7
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

2571748:FAZ98 RS14310
gene id: 2571748:FAZ98_RS14310
uniprot id: A0A7Z2GJV3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

2571748:FAZ98 RS27520
gene id: 2571748:FAZ98_RS27520
uniprot id: A0A7Z2JIT6
names: Subcellular Location Annotation
messages: Cytoplasm

2571748:FAZ98 RS02975
gene id: 2571748:FAZ98_RS02975
uniprot id: A0A7Z2GFD7
names: Cofactor
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Binds 1 Fe(3+) ion per subunit.

2571748:FAZ98 RS12920
gene id: 2571748:FAZ98_RS12920
uniprot id: A0A7Z2JGK8
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

2571748:FAZ98 RS05120
gene id: 2571748:FAZ98_RS05120
uniprot id: A0A7Z2JER3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

2571748:FAZ98 RS04355
gene id: 2571748:FAZ98_RS04355
uniprot id: A0A7Z2GFU9
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain.

2571748:FAZ98 RS10105
gene id: 2571748:FAZ98_RS10105
uniprot id: A0A7Z2GHS6
names: Function
names: Similarity
messages: Belongs to the MinE family.
messages: Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.

2571748:FAZ98 RS05755
gene id: 2571748:FAZ98_RS05755
uniprot id: A0A7Z2GGC3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

2571748:FAZ98 RS13005
gene id: 2571748:FAZ98_RS13005
uniprot id: A0A7Z2GIZ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

2571748:FAZ98 RS00200
gene id: 2571748:FAZ98_RS00200
uniprot id: A0A7Z2GEY3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

2571748:FAZ98 RS07615
gene id: 2571748:FAZ98_RS07615
uniprot id: A0A7Z2JDU5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

2571748:FAZ98 RS13955
gene id: 2571748:FAZ98_RS13955
uniprot id: A0A7Z2GJ40
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

2571748:FAZ98 RS12835
gene id: 2571748:FAZ98_RS12835
uniprot id: A0A7Z2JEQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

2571748:FAZ98 RS12890
gene id: 2571748:FAZ98_RS12890
uniprot id: A0A7Z2GIR1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

2571748:FAZ98 RS14125
gene id: 2571748:FAZ98_RS14125
uniprot id: A0A7Z2GJT4
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

2571748:FAZ98 RS12915
gene id: 2571748:FAZ98_RS12915
uniprot id: A0A7Z2JG47
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.