2562449:E4Z61 RS18670
gene id: 2562449:E4Z61_RS18670
uniprot id: A0A4V1BQ78
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Monomer.

2562449:E4Z61 RS08270
gene id: 2562449:E4Z61_RS08270
uniprot id: A0A4P7J0K2
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

2562449:E4Z61 RS08140
gene id: 2562449:E4Z61_RS08140
uniprot id: A0A4P7J4Z2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane
messages: Required for the assembly of the rivet at the earliest stage of flagellar biosynthesis.
messages: Role in flagellar biosynthesis.

2562449:E4Z61 RS10420
gene id: 2562449:E4Z61_RS10420
uniprot id: A0A4P7J1I6
names: Similarity
messages: Belongs to the UPF0250 family.

2562449:E4Z61 RS03525
gene id: 2562449:E4Z61_RS03525
uniprot id: A0A4P7IYQ4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0756 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2562449:E4Z61 RS20760
gene id: 2562449:E4Z61_RS20760
uniprot id: A0A4P7J785
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Fe(2+)-trafficking protein family.
messages: Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.
messages: Monomer.

2562449:E4Z61 RS01325
gene id: 2562449:E4Z61_RS01325
uniprot id: A0A4P7J1T8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell membrane
messages: NDH-1 is composed of 13 different subunits. Subunits NuoB, CD, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

2562449:E4Z61 RS18900
gene id: 2562449:E4Z61_RS18900
uniprot id: A0A4P7J5I9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

2562449:E4Z61 RS00365
gene id: 2562449:E4Z61_RS00365
uniprot id: A0A4P7J1C8
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.

2562449:E4Z61 RS19010
gene id: 2562449:E4Z61_RS19010
uniprot id: A0A4P7J8U3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

2562449:E4Z61 RS17905
gene id: 2562449:E4Z61_RS17905
uniprot id: A0A4P7J9G3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

2562449:E4Z61 RS19000
gene id: 2562449:E4Z61_RS19000
uniprot id: A0A4P7JA09
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

2562449:E4Z61 RS00180
gene id: 2562449:E4Z61_RS00180
uniprot id: A0A4P7IXP7
names: Similarity
messages: Belongs to the aminoglycoside phosphotransferase family.

2562449:E4Z61 RS17270
gene id: 2562449:E4Z61_RS17270
uniprot id: A0A4P7J957
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Dimer of large and small chains.

2562449:E4Z61 RS19515
gene id: 2562449:E4Z61_RS19515
uniprot id: A0A4P7J6P5
names: Function
names: Similarity
messages: Belongs to the ABC transporter superfamily. Outer membrane lipopolysaccharide export (TC 1.B.42) family.
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane. Probably responsible for energy coupling to the transport system.

2562449:E4Z61 RS18870
gene id: 2562449:E4Z61_RS18870
uniprot id: A0A4V1BQ82
names: Similarity
messages: Belongs to the SlyX family.

2562449:E4Z61 RS13105
gene id: 2562449:E4Z61_RS13105
uniprot id: A0A4P7J4A6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

2562449:E4Z61 RS21425
gene id: 2562449:E4Z61_RS21425
uniprot id: A0A4P7JCG4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2562449:E4Z61 RS07705
gene id: 2562449:E4Z61_RS07705
uniprot id: A0A4P7J4Q9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RuvC family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.

2562449:E4Z61 RS11175
gene id: 2562449:E4Z61_RS11175
uniprot id: A0A4P7J6Z8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

2562449:E4Z61 RS06790
gene id: 2562449:E4Z61_RS06790
uniprot id: A0A4V1BPK9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

2562449:E4Z61 RS21715
gene id: 2562449:E4Z61_RS21715
uniprot id: A0A4P7JB80
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsB family.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

2562449:E4Z61 RS01285
gene id: 2562449:E4Z61_RS01285
uniprot id: A0A4P7IY10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0208 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

2562449:E4Z61 RS13825
gene id: 2562449:E4Z61_RS13825
uniprot id: A0A4P7J392
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

2562449:E4Z61 RS03840
gene id: 2562449:E4Z61_RS03840
uniprot id: A0A4P7IYU6
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

2562449:E4Z61 RS08295
gene id: 2562449:E4Z61_RS08295
uniprot id: A0A4P7J1Y7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

2562449:E4Z61 RS18995
gene id: 2562449:E4Z61_RS18995
uniprot id: A0A4P7J5U8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

2562449:E4Z61 RS18955
gene id: 2562449:E4Z61_RS18955
uniprot id: A0A4P7J5K3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

2562449:E4Z61 RS00265
gene id: 2562449:E4Z61_RS00265
uniprot id: A0A4P7IXM4
names: Function
messages: Involved in the transposition of the insertion sequence.

2562449:E4Z61 RS18970
gene id: 2562449:E4Z61_RS18970
uniprot id: A0A4P7JB33
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

2562449:E4Z61 RS14780
gene id: 2562449:E4Z61_RS14780
uniprot id: A0A4P7J3R3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FrdC family.
messages: Cell membrane
messages: Part of an enzyme complex containing four subunits: a flavoprotein (FrdA), an iron-sulfur protein (FrdB), and two hydrophobic anchor proteins (FrdC and FrdD).
messages: Two distinct, membrane-bound, FAD-containing enzymes are responsible for the catalysis of fumarate and succinate interconversion; fumarate reductase is used in anaerobic growth, and succinate dehydrogenase is used in aerobic growth. Anchors the catalytic components of the fumarate reductase complex to the cell inner membrane, binds quinones.

2562449:E4Z61 RS08540
gene id: 2562449:E4Z61_RS08540
uniprot id: A0A4P7J3R4
names: Function
messages: May be involved in the biogenesis of curli organelles.

2562449:E4Z61 RS23170
gene id: 2562449:E4Z61_RS23170
uniprot id: A0A4P7J915
names: Cofactor
names: Function
messages: Binds 1 [2Fe-2S] cluster.
messages: Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins.

2562449:E4Z61 RS19550
gene id: 2562449:E4Z61_RS19550
uniprot id: A0A4P7JAA1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MlaE permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the ABC transporter complex MlaFEDB, which is involved in a phospholipid transport pathway that maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (MlaF), two transmembrane proteins (MlaE), two cytoplasmic solute-binding proteins (MlaB) and six periplasmic solute-binding proteins (MlaD).

2562449:E4Z61 RS19660
gene id: 2562449:E4Z61_RS19660
uniprot id: A0A4P7J5X3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

2562449:E4Z61 RS18325
gene id: 2562449:E4Z61_RS18325
uniprot id: A0A4P7J8A6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division. Important for assembly or stability of the septal ring.

2562449:E4Z61 RS09915
gene id: 2562449:E4Z61_RS09915
uniprot id: A0A4P7J195
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

2562449:E4Z61 RS19345
gene id: 2562449:E4Z61_RS19345
uniprot id: A0A4P7J611
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AaeX family.
messages: Cell membrane

2562449:E4Z61 RS16015
gene id: 2562449:E4Z61_RS16015
uniprot id: A0A4P7J529
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MetJ family.
messages: Cytoplasm
messages: Does not bind DNA by a helix-turn-helix motif.
messages: Homodimer.
messages: This regulatory protein, when combined with SAM (S-adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis.

2562449:E4Z61 RS00910
gene id: 2562449:E4Z61_RS00910
uniprot id: A0A4P7J1L5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

2562449:E4Z61 RS12580
gene id: 2562449:E4Z61_RS12580
uniprot id: A0A4V1BPW6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RcsF family.
messages: Cell outer membrane
messages: Essential component of the Rcs signaling system, which controls transcription of numerous genes. Plays a role in signal transduction from the cell surface to the histidine kinase RcsC. May detect outer membrane defects.

2562449:E4Z61 RS15595
gene id: 2562449:E4Z61_RS15595
uniprot id: A0A4V1BQ22
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S51 family.
messages: Cytoplasm
messages: Hydrolyzes dipeptides containing N-terminal aspartate residues. May play a role in allowing the cell to use peptide aspartate to spare carbon otherwise required for the synthesis of the aspartate family of amino acids.

2562449:E4Z61 RS21090
gene id: 2562449:E4Z61_RS21090
uniprot id: A0A4P7JCA8
names: Function
names: Similarity
messages: Belongs to the flavodoxin family.
messages: Low-potential electron donor to a number of redox enzymes.

2562449:E4Z61 RS03830
gene id: 2562449:E4Z61_RS03830
uniprot id: A0A4P7IZ31
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-3 family.
messages: Cytoplasm
messages: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
messages: Monomer.

2562449:E4Z61 RS16045
gene id: 2562449:E4Z61_RS16045
uniprot id: A0A4P7J4C2
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

2562449:E4Z61 RS00185
gene id: 2562449:E4Z61_RS00185
uniprot id: A0A4P7IXM4
names: Function
messages: Involved in the transposition of the insertion sequence.

2562449:E4Z61 RS17110
gene id: 2562449:E4Z61_RS17110
uniprot id: A0A4P7J7P4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

2562449:E4Z61 RS03850
gene id: 2562449:E4Z61_RS03850
uniprot id: A0A4P7J1M4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

2562449:E4Z61 RS01265
gene id: 2562449:E4Z61_RS01265
uniprot id: A0A4P7IYP5
names: Similarity
messages: Belongs to the Nudix hydrolase family.

2562449:E4Z61 RS03250
gene id: 2562449:E4Z61_RS03250
uniprot id: A0A4P7IYL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2562449:E4Z61 RS17125
gene id: 2562449:E4Z61_RS17125
uniprot id: A0A4V1BQ49
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

2562449:E4Z61 RS16840
gene id: 2562449:E4Z61_RS16840
uniprot id: A0A4P7J4M3
names: Similarity
messages: Belongs to the UPF0438 family.

2562449:E4Z61 RS15775
gene id: 2562449:E4Z61_RS15775
uniprot id: A0A4P7J5M7
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

2562449:E4Z61 RS01335
gene id: 2562449:E4Z61_RS01335
uniprot id: A0A4P7IYY6
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

2562449:E4Z61 RS00295
gene id: 2562449:E4Z61_RS00295
uniprot id: A0A4P7IXM4
names: Function
messages: Involved in the transposition of the insertion sequence.

2562449:E4Z61 RS16995
gene id: 2562449:E4Z61_RS16995
uniprot id: A0A4P7J4Q2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has four main subunits: a(1), b(1), b'(1) and c(9-12).
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

2562449:E4Z61 RS21430
gene id: 2562449:E4Z61_RS21430
uniprot id: A0A4V1BQC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0382 family.
messages: Membrane

2562449:E4Z61 RS00530
gene id: 2562449:E4Z61_RS00530
uniprot id: A0A4P7IXT3
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.

2562449:E4Z61 RS23185
gene id: 2562449:E4Z61_RS23185
uniprot id: A0A4P7J7Q1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HesB/IscA family.
messages: Binds 2 iron ions per dimer. The dimer may bind additional iron ions.
messages: Homodimer; may form tetramers and higher multimers.
messages: Is able to transfer iron-sulfur clusters to apo-ferredoxin. Multiple cycles of [2Fe2S] cluster formation and transfer are observed, suggesting that IscA acts catalytically. Recruits intracellular free iron so as to provide iron for the assembly of transient iron-sulfur cluster in IscU in the presence of IscS, L-cysteine and the thioredoxin reductase system TrxA/TrxB.

2562449:E4Z61 RS02430
gene id: 2562449:E4Z61_RS02430
uniprot id: A0A4P7IZD4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uridine kinase family.
messages: Cytoplasm

2562449:E4Z61 RS11500
gene id: 2562449:E4Z61_RS11500
uniprot id: A0A4V1BPU6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
messages: Forms an icosahedral capsid composed of 60 subunits, arranged as a dodecamer of pentamers.

2562449:E4Z61 RS12660
gene id: 2562449:E4Z61_RS12660
uniprot id: A0A4P7J713
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

2562449:E4Z61 RS23550
gene id: 2562449:E4Z61_RS23550
uniprot id: A0A4P7J7U6
names: Function
names: Subcellular Location Annotation
messages: Bacterial microcompartment
messages: The 1,2-PD-specific bacterial microcompartment (BMC) concentrates low levels of 1,2-PD catabolic enzymes, concentrates volatile reaction intermediates thus enhancing pathway flux and keeps the level of toxic, mutagenic propionaldehyde low.

2562449:E4Z61 RS00455
gene id: 2562449:E4Z61_RS00455
uniprot id: A0A4P7J1D4
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

2562449:E4Z61 RS11520
gene id: 2562449:E4Z61_RS11520
uniprot id: A0A4P7J292
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleoside-specific channel-forming outer membrane porin (Tsx) (TC 1.B.10) family.
messages: Cell outer membrane

2562449:E4Z61 RS08080
gene id: 2562449:E4Z61_RS08080
uniprot id: A0A4P7J0L7
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

2562449:E4Z61 RS22775
gene id: 2562449:E4Z61_RS22775
uniprot id: A0A4P7J7B4
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

2562449:E4Z61 RS23205
gene id: 2562449:E4Z61_RS23205
uniprot id: A0A4P7J8A0
names: Similarity
messages: Belongs to the adrenodoxin/putidaredoxin family.

2562449:E4Z61 RS17480
gene id: 2562449:E4Z61_RS17480
uniprot id: A0A4P7J504
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

2562449:E4Z61 RS01885
gene id: 2562449:E4Z61_RS01885
uniprot id: A0A4P7J0S1
names: Function
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.
messages: Catalyzes the ATP-dependent phosphorylation of fructose-l-phosphate to fructose-l,6-bisphosphate.

2562449:E4Z61 RS14820
gene id: 2562449:E4Z61_RS14820
uniprot id: A0A4V1BQ08
names: Similarity
messages: Belongs to the EcnA/EcnB lipoprotein family.

2562449:E4Z61 RS18550
gene id: 2562449:E4Z61_RS18550
uniprot id: A0A4P7J664
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NfuA family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is presumably bound at the interface of two monomers.
messages: Homodimer.
messages: Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins.

2562449:E4Z61 RS18585
gene id: 2562449:E4Z61_RS18585
uniprot id: A0A4P7J9T4
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family. GreB subfamily.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length.

2562449:E4Z61 RS17545
gene id: 2562449:E4Z61_RS17545
uniprot id: A0A4P7J9A3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

2562449:E4Z61 RS19070
gene id: 2562449:E4Z61_RS19070
uniprot id: A0A4P7JB57
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

2562449:E4Z61 RS09890
gene id: 2562449:E4Z61_RS09890
uniprot id: A0A4P7J2T1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Pal lipoprotein family.
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

2562449:E4Z61 RS22975
gene id: 2562449:E4Z61_RS22975
uniprot id: A0A4P7J7L6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

2562449:E4Z61 RS14365
gene id: 2562449:E4Z61_RS14365
uniprot id: A0A4P7J3I7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

2562449:E4Z61 RS21870
gene id: 2562449:E4Z61_RS21870
uniprot id: A0A4V1BQI4
names: Similarity
messages: Belongs to the HupF/HypC family.

2562449:E4Z61 RS13645
gene id: 2562449:E4Z61_RS13645
uniprot id: A0A4P7J7J0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/UDP phosphorylase family.
messages: Catalyzes the reversible phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
messages: Homohexamer; trimer of homodimers.

2562449:E4Z61 RS01350
gene id: 2562449:E4Z61_RS01350
uniprot id: A0A4P7IY08
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

2562449:E4Z61 RS18965
gene id: 2562449:E4Z61_RS18965
uniprot id: A0A4P7J6D9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

2562449:E4Z61 RS10555
gene id: 2562449:E4Z61_RS10555
uniprot id: A0A4P7J1N9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

2562449:E4Z61 RS02760
gene id: 2562449:E4Z61_RS02760
uniprot id: A0A4P7IZI7
names: Similarity
messages: Belongs to the UPF0265 family.

2562449:E4Z61 RS17670
gene id: 2562449:E4Z61_RS17670
uniprot id: A0A4P7JAF0
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

2562449:E4Z61 RS00215
gene id: 2562449:E4Z61_RS00215
uniprot id: A0A4P7IY98
names: Similarity
messages: Belongs to the aminoglycoside phosphotransferase family.

2562449:E4Z61 RS20805
gene id: 2562449:E4Z61_RS20805
uniprot id: A0A4P7J6E7
names: Similarity
messages: Belongs to the UPF0235 family.

2562449:E4Z61 RS11230
gene id: 2562449:E4Z61_RS11230
uniprot id: A0A4P7J708
names: Similarity
messages: Belongs to the Hha/YmoA/Cnu family.

2562449:E4Z61 RS01960
gene id: 2562449:E4Z61_RS01960
uniprot id: A0A4P7IY92
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.
messages: Toroid-shaped homodecamer, composed of two pentamers of five dimers.

2562449:E4Z61 RS09210
gene id: 2562449:E4Z61_RS09210
uniprot id: A0A4P7J1V5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

2562449:E4Z61 RS22085
gene id: 2562449:E4Z61_RS22085
uniprot id: A0A4P7JBD1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LuxS family.
messages: Binds 1 Fe cation per subunit.
messages: Homodimer.
messages: Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).

2562449:E4Z61 RS00280
gene id: 2562449:E4Z61_RS00280
uniprot id: A0A4P7IYI3
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.

2562449:E4Z61 RS20810
gene id: 2562449:E4Z61_RS20810
uniprot id: A0A4P7J9P3
names: Similarity
messages: Belongs to the YggT family.

2562449:E4Z61 RS01320
gene id: 2562449:E4Z61_RS01320
uniprot id: A0A4P7IYQ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 is composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

2562449:E4Z61 RS19060
gene id: 2562449:E4Z61_RS19060
uniprot id: A0A4P7J8V5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

2562449:E4Z61 RS23655
gene id: 2562449:E4Z61_RS23655
uniprot id: A0A4P7J7Q6
names: Subcellular Location Annotation
messages: Cytoplasm

2562449:E4Z61 RS22890
gene id: 2562449:E4Z61_RS22890
uniprot id: A0A4P7J849
names: Similarity
messages: Belongs to the thioredoxin family.

2562449:E4Z61 RS08075
gene id: 2562449:E4Z61_RS08075
uniprot id: A0A4P7J0P0
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

2562449:E4Z61 RS15885
gene id: 2562449:E4Z61_RS15885
uniprot id: A0A4P7J496
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Homodimer.
messages: Represses the transcription of fabB, involved in unsaturated fatty acid (UFA) biosynthesis. By controlling UFA production, FabR directly influences the physical properties of the membrane bilayer.

2562449:E4Z61 RS00370
gene id: 2562449:E4Z61_RS00370
uniprot id: A0A4P7IXT1
names: Similarity
messages: Belongs to the peptidase S24 family.

2562449:E4Z61 RS11365
gene id: 2562449:E4Z61_RS11365
uniprot id: A0A4P7J6E8
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

2562449:E4Z61 RS17540
gene id: 2562449:E4Z61_RS17540
uniprot id: A0A4P7J513
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

2562449:E4Z61 RS09375
gene id: 2562449:E4Z61_RS09375
uniprot id: A0A4P7J438
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

2562449:E4Z61 RS19625
gene id: 2562449:E4Z61_RS19625
uniprot id: A0A4P7JBF8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
messages: Cytoplasm
messages: Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.

2562449:E4Z61 RS18980
gene id: 2562449:E4Z61_RS18980
uniprot id: A0A4P7J756
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

2562449:E4Z61 RS18945
gene id: 2562449:E4Z61_RS18945
uniprot id: A0A4P7J5U0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

2562449:E4Z61 RS05500
gene id: 2562449:E4Z61_RS05500
uniprot id: A0A4V1BPI6
names: Similarity
messages: Belongs to the FrmR/RcnR family.

2562449:E4Z61 RS03835
gene id: 2562449:E4Z61_RS03835
uniprot id: A0A4P7J2Z9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

2562449:E4Z61 RS19005
gene id: 2562449:E4Z61_RS19005
uniprot id: A0A4P7J5L2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

2562449:E4Z61 RS23480
gene id: 2562449:E4Z61_RS23480
uniprot id: A0A4P7JDE4
names: Function
names: Subcellular Location Annotation
messages: Bacterial microcompartment
messages: The 1,2-PD-specific bacterial microcompartment (BMC) concentrates low levels of 1,2-PD catabolic enzymes, concentrates volatile reaction intermediates thus enhancing pathway flux and keeps the level of toxic, mutagenic propionaldehyde low.

2562449:E4Z61 RS23210
gene id: 2562449:E4Z61_RS23210
uniprot id: A0A4P7JD99
names: Function
names: Similarity
messages: Belongs to the IscX family.
messages: May function as iron donor in the assembly of iron-sulfur clusters.

2562449:E4Z61 RS23195
gene id: 2562449:E4Z61_RS23195
uniprot id: A0A4P7J7H1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HscB family.
messages: Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA.
messages: Interacts with HscA and stimulates its ATPase activity. Interacts with IscU.

2562449:E4Z61 RS03290
gene id: 2562449:E4Z61_RS03290
uniprot id: A0A4P7IYR9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HflD family.
messages: Cell membrane
messages: Cytoplasm

2562449:E4Z61 RS18975
gene id: 2562449:E4Z61_RS18975
uniprot id: A0A4V1BQ84
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

2562449:E4Z61 RS14855
gene id: 2562449:E4Z61_RS14855
uniprot id: A0A4P7J3R6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

2562449:E4Z61 RS00015
gene id: 2562449:E4Z61_RS00015
uniprot id: A0A4P7IY75
names: Similarity
messages: Belongs to the GSP E family.

2562449:E4Z61 RS02785
gene id: 2562449:E4Z61_RS02785
uniprot id: A0A4P7IYE7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial microcompartment
messages: Belongs to the bacterial microcompartments protein family.
messages: The 1,2-PD-specific bacterial microcompartment (BMC) concentrates low levels of 1,2-PD catabolic enzymes, concentrates volatile reaction intermediates thus enhancing pathway flux and keeps the level of toxic, mutagenic propionaldehyde low.

2562449:E4Z61 RS13110
gene id: 2562449:E4Z61_RS13110
uniprot id: A0A4P7J2X4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell membrane
messages: Self-interacts. Interacts with FtsZ.

2562449:E4Z61 RS00460
gene id: 2562449:E4Z61_RS00460
uniprot id: A0A4V1BP91
names: Similarity
messages: Belongs to the antirestriction protein family.

2562449:E4Z61 RS03860
gene id: 2562449:E4Z61_RS03860
uniprot id: A0A4P7J326
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

2562449:E4Z61 RS16060
gene id: 2562449:E4Z61_RS16060
uniprot id: A0A4P7J762
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RraA family.
messages: Cytoplasm
messages: Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome.
messages: Homotrimer. Binds to both RNA-binding sites in the C-terminal region of Rne and to RhlB.

2562449:E4Z61 RS11545
gene id: 2562449:E4Z61_RS11545
uniprot id: A0A4P7J7D7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YajC family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the SecDF-YidC-YajC translocase complex. The SecDF-YidC-YajC translocase forms a supercomplex with SecYEG, called the holo-translocon (HTL).
messages: The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions.

2562449:E4Z61 RS20470
gene id: 2562449:E4Z61_RS20470
uniprot id: A0A4P7J6G5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZIP transporter (TC 2.A.5) family. ZupT subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mediates zinc uptake. May also transport other divalent cations.
messages: Membrane

2562449:E4Z61 RS04515
gene id: 2562449:E4Z61_RS04515
uniprot id: A0A4P7IZ77
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

2562449:E4Z61 RS19120
gene id: 2562449:E4Z61_RS19120
uniprot id: A0A4P7JB67
names: Similarity
messages: Belongs to the Smg family.

2562449:E4Z61 RS00275
gene id: 2562449:E4Z61_RS00275
uniprot id: A0A4V1BP88
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. TCR/Tet family.
messages: Cell inner membrane
messages: Membrane
messages: Resistance to tetracycline by an active tetracycline efflux. This is an energy-dependent process that decreases the accumulation of the antibiotic in whole cells. This protein functions as a metal-tetracycline/H(+) antiporter.

2562449:E4Z61 RS19405
gene id: 2562449:E4Z61_RS19405
uniprot id: A0A4P7J5S6
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

2562449:E4Z61 RS19590
gene id: 2562449:E4Z61_RS19590
uniprot id: A0A4P7J626
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

2562449:E4Z61 RS17485
gene id: 2562449:E4Z61_RS17485
uniprot id: A0A4P7J994
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

2562449:E4Z61 RS21750
gene id: 2562449:E4Z61_RS21750
uniprot id: A0A4P7J6X2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoS subfamily.
messages: Cytoplasm
messages: Interacts with the RNA polymerase core enzyme.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the master transcriptional regulator of the stationary phase and the general stress response.

2562449:E4Z61 RS11360
gene id: 2562449:E4Z61_RS11360
uniprot id: A0A4P7J265
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

2562449:E4Z61 RS01365
gene id: 2562449:E4Z61_RS01365
uniprot id: A0A4P7J0G7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

2562449:E4Z61 RS01690
gene id: 2562449:E4Z61_RS01690
uniprot id: A0A4V1BPB5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmB/CycW/HelB family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

2562449:E4Z61 RS19025
gene id: 2562449:E4Z61_RS19025
uniprot id: A0A4V1BQ85
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

2562449:E4Z61 RS13655
gene id: 2562449:E4Z61_RS13655
uniprot id: A0A4P7J605
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
messages: Homodimer.
messages: The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis.

2562449:E4Z61 RS10450
gene id: 2562449:E4Z61_RS10450
uniprot id: A0A4P7J1L9
names: Subcellular Location Annotation
messages: Cytoplasm

2562449:E4Z61 RS01770
gene id: 2562449:E4Z61_RS01770
uniprot id: A0A4P7IY60
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

2562449:E4Z61 RS12960
gene id: 2562449:E4Z61_RS12960
uniprot id: A0A4P7J2W7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm
messages: Purine salvage pathway enzyme which catalyzes the transfer of the ribosyl-5-phosphate group from 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to the N9 position of hypoxanthine to yield IMP (inosine 5'-monophosphate). To a lesser extent, can also act on guanine leading to GMP, but shows a highly less efficient activity with xanthine.

2562449:E4Z61 RS16980
gene id: 2562449:E4Z61_RS16980
uniprot id: A0A4P7J4R9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

2562449:E4Z61 RS15765
gene id: 2562449:E4Z61_RS15765
uniprot id: A0A4P7J9H8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.
messages: Protein L10 is also a translational repressor protein. It controls the translation of the rplJL-rpoBC operon by binding to its mRNA.

2562449:E4Z61 RS00175
gene id: 2562449:E4Z61_RS00175
uniprot id: A0A4P7IXI0
names: Function
messages: Involved in the transposition of the insertion sequence.

2562449:E4Z61 RS16475
gene id: 2562449:E4Z61_RS16475
uniprot id: A0A4P7J4I3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TrkH potassium transport family.
messages: Cell inner membrane
messages: Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA.
messages: Membrane

2562449:E4Z61 RS17105
gene id: 2562449:E4Z61_RS17105
uniprot id: A0A4P7J4S0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

2562449:E4Z61 RS00075
gene id: 2562449:E4Z61_RS00075
uniprot id: A0A4P7IXI8
names: Similarity
messages: Belongs to the peptidase A24 family.

2562449:E4Z61 RS19305
gene id: 2562449:E4Z61_RS19305
uniprot id: A0A4P7J5Q9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

2562449:E4Z61 RS13440
gene id: 2562449:E4Z61_RS13440
uniprot id: A0A4P7J5W7
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

2562449:E4Z61 RS20985
gene id: 2562449:E4Z61_RS20985
uniprot id: A0A4V1BQC1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LysR transcriptional regulatory family.
messages: Controls the transcription of genes involved in arginine and lysine metabolism.
messages: Homodimer.

2562449:E4Z61 RS18165
gene id: 2562449:E4Z61_RS18165
uniprot id: A0A4P7J9K8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm
messages: Required for resistance to DNA-damaging agents.

2562449:E4Z61 RS19030
gene id: 2562449:E4Z61_RS19030
uniprot id: A0A4P7J765
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

2562449:E4Z61 RS04075
gene id: 2562449:E4Z61_RS04075
uniprot id: A0A4P7J362
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A highly abundant outer membrane lipoprotein that controls the distance between the inner and outer membranes. The only protein known to be covalently linked to the peptidoglycan network (PGN). Also non-covalently binds the PGN. The link between the cell outer membrane and PGN contributes to maintenance of the structural and functional integrity of the cell envelope, and maintains the correct distance between the PGN and the outer membrane.
messages: Belongs to the Lpp family.
messages: Cell outer membrane
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: cell wall

2562449:E4Z61 RS22040
gene id: 2562449:E4Z61_RS22040
uniprot id: A0A4P7J8I5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small RNA(s).
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

2562449:E4Z61 RS17655
gene id: 2562449:E4Z61_RS17655
uniprot id: A0A4P7J508
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.

2562449:E4Z61 RS23055
gene id: 2562449:E4Z61_RS23055
uniprot id: A0A4V1BQF8
names: Similarity
messages: Belongs to the P(II) protein family.

2562449:E4Z61 RS09215
gene id: 2562449:E4Z61_RS09215
uniprot id: A0A4P7J5Z1
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS1 family.
messages: Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.

2562449:E4Z61 RS00270
gene id: 2562449:E4Z61_RS00270
uniprot id: A0A4P7J1A9
names: Function
messages: TetR is the repressor of the tetracycline resistance element; its N-terminal region forms a helix-turn-helix structure and binds DNA. Binding of tetracycline to TetR reduces the repressor affinity for the tetracycline resistance gene (tetA) promoter operator sites.

2562449:E4Z61 RS06035
gene id: 2562449:E4Z61_RS06035
uniprot id: A0A4P7IZT8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2562449:E4Z61 RS01590
gene id: 2562449:E4Z61_RS01590
uniprot id: A0A4P7IY48
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the RcsB family.
messages: Component of the Rcs signaling system, which controls transcription of numerous genes. RcsB is the response regulator that binds to regulatory DNA regions.
messages: Interacts with RcsD.
messages: Phosphorylated and activated by RcsD.

2562449:E4Z61 RS18575
gene id: 2562449:E4Z61_RS18575
uniprot id: A0A4P7J5M4
names: Similarity
messages: Belongs to the FeoA family.

2562449:E4Z61 RS02250
gene id: 2562449:E4Z61_RS02250
uniprot id: A0A4P7IY77
names: Subcellular Location Annotation
messages: Cytoplasm

2562449:E4Z61 RS14530
gene id: 2562449:E4Z61_RS14530
uniprot id: A0A4P7J3L5
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

2562449:E4Z61 RS17185
gene id: 2562449:E4Z61_RS17185
uniprot id: A0A4P7J694
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with aggregated proteins, together with IbpB, to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress. Aggregated proteins bound to the IbpAB complex are more efficiently refolded and reactivated by the ATP-dependent chaperone systems ClpB and DnaK/DnaJ/GrpE. Its activity is ATP-independent.
messages: Belongs to the small heat shock protein (HSP20) family.
messages: Cytoplasm
messages: Monomer. Forms homomultimers of about 100-150 subunits at optimal growth temperatures. Conformation changes to monomers at high temperatures or high ionic concentrations.

2562449:E4Z61 RS18565
gene id: 2562449:E4Z61_RS18565
uniprot id: A0A4P7J6Y9
names: Function
names: Similarity
messages: Belongs to the FeoC family.
messages: May function as a transcriptional regulator that controls feoABC expression.

2562449:E4Z61 RS15760
gene id: 2562449:E4Z61_RS15760
uniprot id: A0A4P7J4Y7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

2562449:E4Z61 RS04565
gene id: 2562449:E4Z61_RS04565
uniprot id: A0A4P7IZ88
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

2562449:E4Z61 RS19045
gene id: 2562449:E4Z61_RS19045
uniprot id: A0A4P7J5V6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

2562449:E4Z61 RS07060
gene id: 2562449:E4Z61_RS07060
uniprot id: A0A4P7J4T3
names: Function
names: Similarity
messages: Belongs to the MinE family.
messages: Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.

2562449:E4Z61 RS16770
gene id: 2562449:E4Z61_RS16770
uniprot id: A0A4P7J5C1
names: Similarity
messages: Belongs to the thioredoxin family.

2562449:E4Z61 RS00255
gene id: 2562449:E4Z61_RS00255
uniprot id: A0A4P7IXK0
names: Similarity
messages: Belongs to the site-specific recombinase resolvase family.

2562449:E4Z61 RS15780
gene id: 2562449:E4Z61_RS15780
uniprot id: A0A4P7J463
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NusG family.
messages: Monomer. Interacts with the transcription termination factor Rho and with RNA polymerase.
messages: Participates in transcription elongation, termination and antitermination. In the absence of Rho, increases the rate of transcription elongation by the RNA polymerase (RNAP), probably by partially suppressing pausing. In the presence of Rho, modulates most Rho-dependent termination events by interacting with the RNAP to render the complex more susceptible to the termination activity of Rho. May be required to overcome a kinetic limitation of Rho to function at certain terminators. Also involved in ribosomal RNA transcriptional antitermination.

2562449:E4Z61 RS00235
gene id: 2562449:E4Z61_RS00235
uniprot id: A0A4P7IXI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell inner membrane
messages: Membrane

2562449:E4Z61 RS18990
gene id: 2562449:E4Z61_RS18990
uniprot id: A0A4P7J5U4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

2562449:E4Z61 RS22195
gene id: 2562449:E4Z61_RS22195
uniprot id: A0A4P7J718
names: Similarity
messages: Belongs to the UPF0057 (PMP3) family.

2562449:E4Z61 RS12570
gene id: 2562449:E4Z61_RS12570
uniprot id: A0A4P7J3F0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2562449:E4Z61 RS01985
gene id: 2562449:E4Z61_RS01985
uniprot id: A0A4P7J0U0
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

2562449:E4Z61 RS18960
gene id: 2562449:E4Z61_RS18960
uniprot id: A0A4P7J8T3
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

2562449:E4Z61 RS19240
gene id: 2562449:E4Z61_RS19240
uniprot id: A0A4P7J5Z3
names: Function
names: Similarity
names: Subunit
messages: Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters.
messages: Belongs to the transcriptional regulatory Fis family.
messages: Homodimer.

2562449:E4Z61 RS00210
gene id: 2562449:E4Z61_RS00210
uniprot id: A0A4P7IZZ1
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

2562449:E4Z61 RS11245
gene id: 2562449:E4Z61_RS11245
uniprot id: A0A4P7J201
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

2562449:E4Z61 RS04435
gene id: 2562449:E4Z61_RS04435
uniprot id: A0A4P7J1W2
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family. Monothiol subfamily.
messages: Monothiol glutaredoxin involved in the biogenesis of iron-sulfur clusters.

2562449:E4Z61 RS14070
gene id: 2562449:E4Z61_RS14070
uniprot id: A0A4P7J867
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

2562449:E4Z61 RS01760
gene id: 2562449:E4Z61_RS01760
uniprot id: A0A4P7IY65
names: Similarity
messages: Belongs to the UPF0352 family.

2562449:E4Z61 RS12770
gene id: 2562449:E4Z61_RS12770
uniprot id: A0A4P7J5K4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HesB/IscA family.
messages: Binds 1 iron-sulfur cluster per subunit.
messages: Homodimer.
messages: Required for insertion of 4Fe-4S clusters for at least IspG.

2562449:E4Z61 RS23400
gene id: 2562449:E4Z61_RS23400
uniprot id: A0A4P7JBY8
names: Similarity
messages: Belongs to the SAICAR synthetase family.

2562449:E4Z61 RS14195
gene id: 2562449:E4Z61_RS14195
uniprot id: A0A4P7J3J3
names: Similarity
names: Subunit
messages: Belongs to the RutC family.
messages: Homotrimer.

2562449:E4Z61 RS00510
gene id: 2562449:E4Z61_RS00510
uniprot id: A0A4P7J1E3
names: Function
names: Subunit
messages: Adenylyltransferase that mediates the addition of adenosine 5'-monophosphate (AMP) to specific residues of target proteins.
messages: Homodimer.

2562449:E4Z61 RS07170
gene id: 2562449:E4Z61_RS07170
uniprot id: A0A4P7J1F3
names: Subcellular Location Annotation
messages: Cytoplasm

2562449:E4Z61 RS09220
gene id: 2562449:E4Z61_RS09220
uniprot id: A0A4V1BPQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

2562449:E4Z61 RS00095
gene id: 2562449:E4Z61_RS00095
uniprot id: A0A4P7J186
names: Similarity
messages: Belongs to the GSP E family.

2562449:E4Z61 RS18950
gene id: 2562449:E4Z61_RS18950
uniprot id: A0A4P7J9Z8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

2562449:E4Z61 RS02090
gene id: 2562449:E4Z61_RS02090
uniprot id: A0A4P7IY58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0387 family.
messages: Cell membrane

2562449:E4Z61 RS17010
gene id: 2562449:E4Z61_RS17010
uniprot id: A0A4P7JA45
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

2562449:E4Z61 RS08350
gene id: 2562449:E4Z61_RS08350
uniprot id: A0A4P7J1Z4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

2562449:E4Z61 RS12825
gene id: 2562449:E4Z61_RS12825
uniprot id: A0A4P7J3J4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DksA family.
messages: Cytoplasm
messages: Interacts directly with the RNA polymerase.
messages: Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression.

2562449:E4Z61 RS19040
gene id: 2562449:E4Z61_RS19040
uniprot id: A0A4P7J5V2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

2562449:E4Z61 RS14815
gene id: 2562449:E4Z61_RS14815
uniprot id: A0A4P7J922
names: Similarity
messages: Belongs to the EcnA/EcnB lipoprotein family.

2562449:E4Z61 RS19695
gene id: 2562449:E4Z61_RS19695
uniprot id: A0A4P7J7H6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

2562449:E4Z61 RS14535
gene id: 2562449:E4Z61_RS14535
uniprot id: A0A4P7J6F4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

2562449:E4Z61 RS23180
gene id: 2562449:E4Z61_RS23180
uniprot id: A0A4P7J7M9
names: Function
names: Similarity
messages: A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters.
messages: Belongs to the NifU family.

2562449:E4Z61 RS12425
gene id: 2562449:E4Z61_RS12425
uniprot id: A0A4P7J6X8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Membrane

2562449:E4Z61 RS19050
gene id: 2562449:E4Z61_RS19050
uniprot id: A0A4P7JA18
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

2562449:E4Z61 RS19965
gene id: 2562449:E4Z61_RS19965
uniprot id: A0A4V1BQA2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the serine/threonine dehydratase family.
messages: Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. TdcB also dehydrates serine to yield pyruvate via analogous enamine/imine intermediates.
messages: In the native structure, TdcB is in a dimeric form, whereas in the TdcB-AMP complex, it exists in a tetrameric form (dimer of dimers).

2562449:E4Z61 RS00090
gene id: 2562449:E4Z61_RS00090
uniprot id: A0A4P7IY83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

2562449:E4Z61 RS19495
gene id: 2562449:E4Z61_RS19495
uniprot id: A0A4P7J637
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RapZ-like family. RapZ subfamily.
messages: Homotrimer.
messages: Modulates the synthesis of GlmS, by affecting the processing and stability of the regulatory small RNA GlmZ. When glucosamine-6-phosphate (GlcN6P) concentrations are high in the cell, RapZ binds GlmZ and targets it to cleavage by RNase E. Consequently, GlmZ is inactivated and unable to activate GlmS synthesis. Under low GlcN6P concentrations, RapZ is sequestered and inactivated by an other regulatory small RNA, GlmY, preventing GlmZ degradation and leading to synthesis of GlmS.

2562449:E4Z61 RS19055
gene id: 2562449:E4Z61_RS19055
uniprot id: A0A4P7J5M1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

2562449:E4Z61 RS16985
gene id: 2562449:E4Z61_RS16985
uniprot id: A0A4P7J4S5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

2562449:E4Z61 RS20360
gene id: 2562449:E4Z61_RS20360
uniprot id: A0A4P7J7S2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

2562449:E4Z61 RS15685
gene id: 2562449:E4Z61_RS15685
uniprot id: A0A4P7J468
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

2562449:E4Z61 RS03170
gene id: 2562449:E4Z61_RS03170
uniprot id: A0A4P7IYP8
names: Similarity
messages: Belongs to the UPF0227 family.

2562449:E4Z61 RS18935
gene id: 2562449:E4Z61_RS18935
uniprot id: A0A4P7J5J6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

2562449:E4Z61 RS07205
gene id: 2562449:E4Z61_RS07205
uniprot id: A0A4P7J0W7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

2562449:E4Z61 RS19785
gene id: 2562449:E4Z61_RS19785
uniprot id: A0A4P7J984
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SIS family. DiaA subfamily.
messages: Homotetramer; dimer of dimers.
messages: Required for the timely initiation of chromosomal replication via direct interactions with the DnaA initiator protein.

2562449:E4Z61 RS01700
gene id: 2562449:E4Z61_RS01700
uniprot id: A0A4P7IY61
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmD/CycX/HelD family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

2562449:E4Z61 RS17115
gene id: 2562449:E4Z61_RS17115
uniprot id: A0A4P7J5H4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

2562449:E4Z61 RS13465
gene id: 2562449:E4Z61_RS13465
uniprot id: A0A4P7J4G5
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

2562449:E4Z61 RS18985
gene id: 2562449:E4Z61_RS18985
uniprot id: A0A4P7J5K5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

2562449:E4Z61 RS13165
gene id: 2562449:E4Z61_RS13165
uniprot id: A0A4P7J313
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsL family.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
messages: Membrane
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

2562449:E4Z61 RS19570
gene id: 2562449:E4Z61_RS19570
uniprot id: A0A4P7JBF0
names: Similarity
messages: Belongs to the BolA/IbaG family.

2562449:E4Z61 RS17920
gene id: 2562449:E4Z61_RS17920
uniprot id: A0A4P7J5V8
names: Subcellular Location Annotation
messages: Cytoplasm

2562449:E4Z61 RS12700
gene id: 2562449:E4Z61_RS12700
uniprot id: A0A4P7J2R9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

2562449:E4Z61 RS11345
gene id: 2562449:E4Z61_RS11345
uniprot id: A0A4P7J3F1
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

2562449:E4Z61 RS18290
gene id: 2562449:E4Z61_RS18290
uniprot id: A0A4V1BQ71
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sulfur carrier protein TusA family.
messages: Cytoplasm
messages: Interacts with IscS.
messages: Sulfur carrier protein involved in sulfur trafficking in the cell. Part of a sulfur-relay system required for 2-thiolation during synthesis of 2-thiouridine of the modified wobble base 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) in tRNA. Interacts with IscS and stimulates its cysteine desulfurase activity. Accepts an activated sulfur from IscS, which is then transferred to TusD, and thus determines the direction of sulfur flow from IscS to 2-thiouridine formation. Also appears to be involved in sulfur transfer for the biosynthesis of molybdopterin.

2562449:E4Z61 RS21695
gene id: 2562449:E4Z61_RS21695
uniprot id: A0A4P7J8D2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PAPS reductase family. CysD subfamily.
messages: Heterodimer composed of CysD, the smaller subunit, and CysN.
messages: With CysN forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.

2562449:E4Z61 RS19400
gene id: 2562449:E4Z61_RS19400
uniprot id: A0A4P7JA73
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

2562449:E4Z61 RS15425
gene id: 2562449:E4Z61_RS15425
uniprot id: A0A4P7J6T5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of sn-l,2-diacylglycerol (DAG) to phosphatidic acid. Involved in the recycling of diacylglycerol produced as a by-product during membrane-derived oligosaccharide (MDO) biosynthesis.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

2562449:E4Z61 RS20055
gene id: 2562449:E4Z61_RS20055
uniprot id: A0A4P7J6Y5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell inner membrane
messages: Membrane

2562449:E4Z61 RS19020
gene id: 2562449:E4Z61_RS19020
uniprot id: A0A4P7JB43
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.