2494701:FY206 RS21495
gene id: 2494701:FY206_RS21495
uniprot id: A0A5C1C4N6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ElaB/YgaM/YqjD family.
messages: Cell inner membrane
messages: Membrane

2494701:FY206 RS08770
gene id: 2494701:FY206_RS08770
uniprot id: A0A5C1BYH7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activation of pyruvate formate-lyase 1 under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Belongs to the organic radical-activating enzymes family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm

2494701:FY206 RS07545
gene id: 2494701:FY206_RS07545
uniprot id: A0A5C1BXN8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Fur family.
messages: Cytoplasm
messages: Homodimer.

2494701:FY206 RS01670
gene id: 2494701:FY206_RS01670
uniprot id: A0A5C1BUI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Membrane

2494701:FY206 RS02540
gene id: 2494701:FY206_RS02540
uniprot id: A0A5C1BUW6
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type I sub-subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The autoendoproteolytic cleavage occurs by a canonical serine protease mechanism, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain. During this reaction, the Ser that is part of the protease active site of the proenzyme becomes the pyruvoyl prosthetic group, which constitutes an essential element of the active site of the mature decarboxylase.

2494701:FY206 RS04200
gene id: 2494701:FY206_RS04200
uniprot id: A0A5C1BVR8
names: Subcellular Location Annotation
messages: Membrane

2494701:FY206 RS00245
gene id: 2494701:FY206_RS00245
uniprot id: A0A5C1BTI1
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

2494701:FY206 RS16185
gene id: 2494701:FY206_RS16185
uniprot id: A0A5C1C1R1
names: Similarity
messages: Belongs to the polysaccharide synthase family.

2494701:FY206 RS15135
gene id: 2494701:FY206_RS15135
uniprot id: A0A5C1C173
names: Similarity
messages: Belongs to the peptidase S14 family.

2494701:FY206 RS14905
gene id: 2494701:FY206_RS14905
uniprot id: A0A5C1C1B8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm
messages: Required for resistance to DNA-damaging agents.

2494701:FY206 RS18250
gene id: 2494701:FY206_RS18250
uniprot id: A0A5C1C2U6
names: Cofactor
names: Similarity
messages: Belongs to the glycosyl hydrolase 4 family.
messages: Binds 1 NAD(+) per subunit.

2494701:FY206 RS03845
gene id: 2494701:FY206_RS03845
uniprot id: A0A5C1BVP2
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

2494701:FY206 RS17280
gene id: 2494701:FY206_RS17280
uniprot id: A0A5C1C353
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane

2494701:FY206 RS23265
gene id: 2494701:FY206_RS23265
uniprot id: A0A5C1C5P8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Metabolite:H+ Symporter (MHS) family (TC 2.A.1.6) family.
messages: Cell inner membrane
messages: Membrane

2494701:FY206 RS02415
gene id: 2494701:FY206_RS02415
uniprot id: A0A5C1BUV1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbD subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps.

2494701:FY206 RS19730
gene id: 2494701:FY206_RS19730
uniprot id: A0A5C1C4P9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2494701:FY206 RS07290
gene id: 2494701:FY206_RS07290
uniprot id: A0A5C1BXK0
names: Similarity
messages: Belongs to the RNase T2 family.

2494701:FY206 RS00815
gene id: 2494701:FY206_RS00815
uniprot id: A0A5C1BU11
names: Similarity
messages: Belongs to the MipA/OmpV family.

2494701:FY206 RS01355
gene id: 2494701:FY206_RS01355
uniprot id: A0A5C1BUC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2494701:FY206 RS24555
gene id: 2494701:FY206_RS24555
uniprot id: A0A5C1C641
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the periplasmic pilus chaperone family.
messages: Periplasm

2494701:FY206 RS18015
gene id: 2494701:FY206_RS18015
uniprot id: A0A5C1C2X6
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane.

2494701:FY206 RS13275
gene id: 2494701:FY206_RS13275
uniprot id: A0A5C1C1L7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

2494701:FY206 RS20505
gene id: 2494701:FY206_RS20505
uniprot id: A0A5C1C3X1
names: Similarity
messages: Belongs to the prokaryotic GSH synthase family.

2494701:FY206 RS04815
gene id: 2494701:FY206_RS04815
uniprot id: A0A5C1BW22
names: Subcellular Location Annotation
messages: Cytoplasm

2494701:FY206 RS19025
gene id: 2494701:FY206_RS19025
uniprot id: A0A5C1C3Q4
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Electron transport system for the ribonucleotide reductase system NrdEF.

2494701:FY206 RS23545
gene id: 2494701:FY206_RS23545
uniprot id: A0A5C1C5M3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mediates influx of magnesium ions.
messages: Membrane

2494701:FY206 RS11635
gene id: 2494701:FY206_RS11635
uniprot id: A0A5C1BZH5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm
messages: Required for resistance to DNA-damaging agents.

2494701:FY206 RS05080
gene id: 2494701:FY206_RS05080
uniprot id: A0A5C1BXD1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

2494701:FY206 RS19550
gene id: 2494701:FY206_RS19550
uniprot id: A0A5C1C3L4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
messages: Heterodimer composed of CysD, the smaller subunit, and CysN.
messages: With CysD forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.

2494701:FY206 RS00465
gene id: 2494701:FY206_RS00465
uniprot id: A0A5C1BUK8
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

2494701:FY206 RS20745
gene id: 2494701:FY206_RS20745
uniprot id: A0A5C1C4B3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

2494701:FY206 RS14725
gene id: 2494701:FY206_RS14725
uniprot id: A0A5C1C109
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

2494701:FY206 RS10480
gene id: 2494701:FY206_RS10480
uniprot id: A0A5C1BZ00
names: Cofactor
names: Similarity
messages: Belongs to the glycosyl hydrolase 4 family.
messages: Binds 1 NAD(+) per subunit.

2494701:FY206 RS24275
gene id: 2494701:FY206_RS24275
uniprot id: A0A5C1C5V7
names: Function
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.
messages: Phosphorylates 6-deoxy-6-sulfo-D-fructose (SF) to 6-deoxy-6-sulfo-D-fructose 1-phosphate (SFP).

2494701:FY206 RS21815
gene id: 2494701:FY206_RS21815
uniprot id: A0A5C1C4L4
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

2494701:FY206 RS21145
gene id: 2494701:FY206_RS21145
uniprot id: A0A5C1C459
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

2494701:FY206 RS09260
gene id: 2494701:FY206_RS09260
uniprot id: A0A5C1BYP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

2494701:FY206 RS24015
gene id: 2494701:FY206_RS24015
uniprot id: A0A5C1C615
names: Similarity
messages: Belongs to the FBPase class 2 family.

2494701:FY206 RS14910
gene id: 2494701:FY206_RS14910
uniprot id: A0A5C1C1R0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyltransferase 20 family.
messages: Homotetramer.
messages: Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-alpha-D-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor.

2494701:FY206 RS12350
gene id: 2494701:FY206_RS12350
uniprot id: A0A5C1C060
names: Similarity
messages: Belongs to the PhzF family.

2494701:FY206 RS24420
gene id: 2494701:FY206_RS24420
uniprot id: A0A5C1C677
names: Subcellular Location Annotation
messages: Membrane

2494701:FY206 RS06600
gene id: 2494701:FY206_RS06600
uniprot id: A0A5C1BXC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0014 family.
messages: Membrane

2494701:FY206 RS14695
gene id: 2494701:FY206_RS14695
uniprot id: A0A5C1C1F9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M23B family.
messages: Membrane

2494701:FY206 RS06700
gene id: 2494701:FY206_RS06700
uniprot id: A0A5C1BXD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the periplasmic pilus chaperone family.
messages: Periplasm

2494701:FY206 RS04160
gene id: 2494701:FY206_RS04160
uniprot id: A0A5C1BWC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell inner membrane
messages: Membrane

2494701:FY206 RS18715
gene id: 2494701:FY206_RS18715
uniprot id: A0A5C1C396
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

2494701:FY206 RS16805
gene id: 2494701:FY206_RS16805
uniprot id: A0A5C1C235
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2494701:FY206 RS22190
gene id: 2494701:FY206_RS22190
uniprot id: A0A5C1C6V5
names: Function
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

2494701:FY206 RS19720
gene id: 2494701:FY206_RS19720
uniprot id: A0A5C1C3N4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily.
messages: Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA.
messages: Cytoplasm
messages: Monomer.

2494701:FY206 RS13845
gene id: 2494701:FY206_RS13845
uniprot id: A0A5C1C6M7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TonB family.
messages: Cell inner membrane
messages: Homodimer. Forms a complex with the accessory proteins ExbB and ExbD.
messages: Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins.

2494701:FY206 RS17220
gene id: 2494701:FY206_RS17220
uniprot id: A0A5C1C2B5
names: Subcellular Location Annotation
messages: Membrane

2494701:FY206 RS24510
gene id: 2494701:FY206_RS24510
uniprot id: A0A5C1C7C9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

2494701:FY206 RS11360
gene id: 2494701:FY206_RS11360
uniprot id: A0A5C1BZN1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family. MdtI subfamily.
messages: Catalyzes the excretion of spermidine.
messages: Cell inner membrane
messages: Cell membrane
messages: Forms a complex with MdtJ.
messages: Membrane

2494701:FY206 RS10000
gene id: 2494701:FY206_RS10000
uniprot id: A0A5C1BYQ7
names: Function
names: Similarity
messages: Belongs to the thiamine kinase family.
messages: Catalyzes the phosphorylation of thiamine to thiamine phosphate.

2494701:FY206 RS07965
gene id: 2494701:FY206_RS07965
uniprot id: A0A5C1BXQ3
names: Similarity
messages: Belongs to the MoaD family.

2494701:FY206 RS09970
gene id: 2494701:FY206_RS09970
uniprot id: A0A5C1BZ49
names: Subcellular Location Annotation
messages: Membrane

2494701:FY206 RS19655
gene id: 2494701:FY206_RS19655
uniprot id: A0A5C1C6T2
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family. GlucD subfamily.

2494701:FY206 RS14085
gene id: 2494701:FY206_RS14085
uniprot id: A0A5C1C0Z0
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

2494701:FY206 RS12405
gene id: 2494701:FY206_RS12405
uniprot id: A0A5C1C0G5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2494701:FY206 RS06195
gene id: 2494701:FY206_RS06195
uniprot id: A0A5C1BWQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

2494701:FY206 RS17240
gene id: 2494701:FY206_RS17240
uniprot id: A0A5C1C2Q2
names: Similarity
messages: Belongs to the Nudix hydrolase family.

2494701:FY206 RS00010
gene id: 2494701:FY206_RS00010
uniprot id: A0A5C1BTA4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

2494701:FY206 RS15940
gene id: 2494701:FY206_RS15940
uniprot id: A0A5C1C2F5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2494701:FY206 RS14930
gene id: 2494701:FY206_RS14930
uniprot id: A0A5C1C146
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 2 family.
messages: Periplasm

2494701:FY206 RS00270
gene id: 2494701:FY206_RS00270
uniprot id: A0A5C1BTJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell outer membrane
messages: Membrane

2494701:FY206 RS00155
gene id: 2494701:FY206_RS00155
uniprot id: A0A5C1BU12
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

2494701:FY206 RS23850
gene id: 2494701:FY206_RS23850
uniprot id: A0A5C1C5K5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm
messages: In the N-terminal section; belongs to the lyase 1 family. Argininosuccinate lyase subfamily.

2494701:FY206 RS06160
gene id: 2494701:FY206_RS06160
uniprot id: A0A5C1BX23
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

2494701:FY206 RS07525
gene id: 2494701:FY206_RS07525
uniprot id: A0A5C1BYK9
names: Subcellular Location Annotation
messages: Membrane

2494701:FY206 RS14110
gene id: 2494701:FY206_RS14110
uniprot id: A0A5C1C0T1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

2494701:FY206 RS16170
gene id: 2494701:FY206_RS16170
uniprot id: A0A5C1C2J1
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

2494701:FY206 RS11095
gene id: 2494701:FY206_RS11095
uniprot id: A0A5C1BZ93
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

2494701:FY206 RS02660
gene id: 2494701:FY206_RS02660
uniprot id: A0A5C1BW39
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

2494701:FY206 RS13210
gene id: 2494701:FY206_RS13210
uniprot id: A0A5C1C1K6
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: 4-aminobutanal can spontaneously cyclize to 1-pyrroline, and 5-aminopentanal to 1-piperideine.
messages: Belongs to the aldehyde dehydrogenase family. Gamma-aminobutyraldehyde dehydrogenase subfamily.
messages: Catalyzes the oxidation 4-aminobutanal (gamma-aminobutyraldehyde) to 4-aminobutanoate (gamma-aminobutyrate or GABA). This is the second step in one of two pathways for putrescine degradation, where putrescine is converted into 4-aminobutanoate via 4-aminobutanal. Also functions as a 5-aminopentanal dehydrogenase in a a L-lysine degradation pathway to succinate that proceeds via cadaverine, glutarate and L-2-hydroxyglutarate.
messages: Homotetramer.

2494701:FY206 RS03035
gene id: 2494701:FY206_RS03035
uniprot id: A0A5C1BV52
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PyrI family.
messages: Binds 1 zinc ion per subunit.
messages: Contains catalytic and regulatory chains.
messages: Heterododecamer (2C3:3R2) of six catalytic PyrB chains organized as two trimers (C3), and six regulatory PyrI chains organized as three dimers (R2).
messages: Involved in allosteric regulation of aspartate carbamoyltransferase.

2494701:FY206 RS06565
gene id: 2494701:FY206_RS06565
uniprot id: A0A5C1BY37
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

2494701:FY206 RS20490
gene id: 2494701:FY206_RS20490
uniprot id: A0A5C1C457
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SprT family.
messages: Binds 1 zinc ion.
messages: Cytoplasm

2494701:FY206 RS09385
gene id: 2494701:FY206_RS09385
uniprot id: A0A5C1BYA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

2494701:FY206 RS23915
gene id: 2494701:FY206_RS23915
uniprot id: A0A5C1C5Z6
names: Cofactor
names: Similarity
messages: Belongs to the iron-containing alcohol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.

2494701:FY206 RS01085
gene id: 2494701:FY206_RS01085
uniprot id: A0A5C1BU32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic pantothenate kinase family.
messages: Cytoplasm

2494701:FY206 RS12950
gene id: 2494701:FY206_RS12950
uniprot id: A0A5C1C039
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Gram-negative porin family.
messages: Cell outer membrane
messages: Homotrimer.
messages: Membrane

2494701:FY206 RS22120
gene id: 2494701:FY206_RS22120
uniprot id: A0A5C1C549
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

2494701:FY206 RS09070
gene id: 2494701:FY206_RS09070
uniprot id: A0A5C1BYG3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dsrC/tusE family.
messages: Cytoplasm
messages: Interacts with the TusBCD complex. Interacts with MnmA.
messages: Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Could accept sulfur from TusD.

2494701:FY206 RS23435
gene id: 2494701:FY206_RS23435
uniprot id: A0A5C1C5P7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: 3'-5' exonuclease that prefers single-stranded DNA and RNA. May play a role in the H(2)O(2)-induced DNA damage repair.
messages: Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family. TatD subfamily.
messages: Cytoplasm
messages: Monomer.

2494701:FY206 RS18000
gene id: 2494701:FY206_RS18000
uniprot id: A0A5C1C409
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48 family. BepA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Functions as both a chaperone and a metalloprotease. Maintains the integrity of the outer membrane by promoting either the assembly or the elimination of outer membrane proteins, depending on their folding state.
messages: Periplasm

2494701:FY206 RS06365
gene id: 2494701:FY206_RS06365
uniprot id: A0A5C1BX59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

2494701:FY206 RS19790
gene id: 2494701:FY206_RS19790
uniprot id: A0A5C1C4Q6
names: Function
names: Similarity
messages: Belongs to the peptidase M16 family.
messages: Endopeptidase that degrades small peptides of less than 7 kDa, such as glucagon and insulin.

2494701:FY206 RS03315
gene id: 2494701:FY206_RS03315
uniprot id: A0A5C1BVA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:galactoside symporter (TC 2.A.2) family.
messages: Membrane

2494701:FY206 RS08910
gene id: 2494701:FY206_RS08910
uniprot id: A0A5C1BYC9
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

2494701:FY206 RS20295
gene id: 2494701:FY206_RS20295
uniprot id: A0A5C1C3Y9
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

2494701:FY206 RS09060
gene id: 2494701:FY206_RS09060
uniprot id: A0A5C1BYL0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RlmI family.
messages: Cytoplasm
messages: Specifically methylates the cytosine at position 1962 (m5C1962) of 23S rRNA.

2494701:FY206 RS08105
gene id: 2494701:FY206_RS08105
uniprot id: A0A5C1BYB4
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

2494701:FY206 RS04120
gene id: 2494701:FY206_RS04120
uniprot id: A0A5C1BVP5
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

2494701:FY206 RS10430
gene id: 2494701:FY206_RS10430
uniprot id: A0A5C1BYZ1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AspA/AstE family. Succinylglutamate desuccinylase subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Transforms N(2)-succinylglutamate into succinate and glutamate.

2494701:FY206 RS23220
gene id: 2494701:FY206_RS23220
uniprot id: A0A5C1C5A9
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

2494701:FY206 RS11340
gene id: 2494701:FY206_RS11340
uniprot id: A0A5C1C0D2
names: Similarity
messages: Belongs to the PhzF family.

2494701:FY206 RS23360
gene id: 2494701:FY206_RS23360
uniprot id: A0A5C1C5J5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

2494701:FY206 RS05905
gene id: 2494701:FY206_RS05905
uniprot id: A0A5C1BXQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

2494701:FY206 RS24970
gene id: 2494701:FY206_RS24970
uniprot id: A0A5C1C6X6
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

2494701:FY206 RS15670
gene id: 2494701:FY206_RS15670
uniprot id: A0A5C1C2B8
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliO/MopB family.
messages: Cell membrane

2494701:FY206 RS09910
gene id: 2494701:FY206_RS09910
uniprot id: A0A5C1BZC7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

2494701:FY206 RS06590
gene id: 2494701:FY206_RS06590
uniprot id: A0A5C1BXJ9
names: Similarity
messages: Belongs to the band 7/mec-2 family.

2494701:FY206 RS20400
gene id: 2494701:FY206_RS20400
uniprot id: A0A5C1C469
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

2494701:FY206 RS15875
gene id: 2494701:FY206_RS15875
uniprot id: A0A5C1C1K4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2494701:FY206 RS20260
gene id: 2494701:FY206_RS20260
uniprot id: A0A5C1C3V1
names: Function
names: Similarity
messages: Belongs to the flavodoxin family.
messages: Low-potential electron donor to a number of redox enzymes.

2494701:FY206 RS09340
gene id: 2494701:FY206_RS09340
uniprot id: A0A5C1BZE7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

2494701:FY206 RS11375
gene id: 2494701:FY206_RS11375
uniprot id: A0A5C1C819
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Asr family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Periplasm
messages: Proteolytic processing gives rise to the active protein.
messages: Required for growth and/or survival at acidic conditions.

2494701:FY206 RS10335
gene id: 2494701:FY206_RS10335
uniprot id: A0A5C1BZ23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S49 family.
messages: Cell inner membrane

2494701:FY206 RS09915
gene id: 2494701:FY206_RS09915
uniprot id: A0A5C1BZ08
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

2494701:FY206 RS09730
gene id: 2494701:FY206_RS09730
uniprot id: A0A5C1BZL4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxL/LpxM/LpxP family.
messages: Catalyzes the transfer of laurate from lauroyl-acyl carrier protein (ACP) to Kdo(2)-lipid IV(A) to form Kdo(2)-(lauroyl)-lipid IV(A).
messages: Cell inner membrane

2494701:FY206 RS16230
gene id: 2494701:FY206_RS16230
uniprot id: A0A5C1C358
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

2494701:FY206 RS04250
gene id: 2494701:FY206_RS04250
uniprot id: A0A5C1BW59
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: Negatively regulates its own expression and that of the subsequent genes in the proximal part of the division and cell wall (dcw) gene cluster. Acts by binding directly to DNA. May also regulate the expression of genes outside the dcw cluster.
messages: nucleoid

2494701:FY206 RS01225
gene id: 2494701:FY206_RS01225
uniprot id: A0A5C1BU74
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

2494701:FY206 RS08345
gene id: 2494701:FY206_RS08345
uniprot id: A0A5C1BXT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAE transporter (TC 2.A.81) family. YbjL subfamily.
messages: Cell membrane

2494701:FY206 RS09920
gene id: 2494701:FY206_RS09920
uniprot id: A0A5C1BZ40
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

2494701:FY206 RS03885
gene id: 2494701:FY206_RS03885
uniprot id: A0A5C1BW76
names: Caution
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. GpmB subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2494701:FY206 RS01650
gene id: 2494701:FY206_RS01650
uniprot id: A0A5C1BV71
names: Subcellular Location Annotation
messages: Membrane

2494701:FY206 RS06415
gene id: 2494701:FY206_RS06415
uniprot id: A0A5C1BY04
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 2 family.
messages: Binds 1 sodium ion per monomer.
messages: Binds 2 magnesium ions per monomer.
messages: Homotetramer.

2494701:FY206 RS05495
gene id: 2494701:FY206_RS05495
uniprot id: A0A5C1BWR5
names: Subcellular Location Annotation
messages: Membrane

2494701:FY206 RS08625
gene id: 2494701:FY206_RS08625
uniprot id: A0A5C1BYD9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ClpS family.
messages: Binds to the N-terminal domain of the chaperone ClpA.
messages: Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.

2494701:FY206 RS09395
gene id: 2494701:FY206_RS09395
uniprot id: A0A5C1BYR7
names: Function
names: Similarity
messages: Belongs to the nitroreductase family. HadB/RutE subfamily.
messages: May reduce toxic product malonic semialdehyde to 3-hydroxypropionic acid, which is excreted.

2494701:FY206 RS21395
gene id: 2494701:FY206_RS21395
uniprot id: A0A5C1C498
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

2494701:FY206 RS17790
gene id: 2494701:FY206_RS17790
uniprot id: A0A5C1C2U0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ZipA family.
messages: Cell inner membrane
messages: Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins.
messages: Interacts with FtsZ via their C-terminal domains.

2494701:FY206 RS13625
gene id: 2494701:FY206_RS13625
uniprot id: A0A5C1C1D4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LapB family.
messages: Cell inner membrane
messages: Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane.

2494701:FY206 RS17075
gene id: 2494701:FY206_RS17075
uniprot id: A0A5C1C308
names: Function
names: Similarity
messages: Belongs to the isochorismate synthase family.
messages: Catalyzes the conversion of chorismate to isochorismate.

2494701:FY206 RS10885
gene id: 2494701:FY206_RS10885
uniprot id: A0A5C1BZF4
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

2494701:FY206 RS10425
gene id: 2494701:FY206_RS10425
uniprot id: A0A5C1C0B1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinylarginine dihydrolase family.
messages: Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO(2).
messages: Homodimer.

2494701:FY206 RS18340
gene id: 2494701:FY206_RS18340
uniprot id: A0A5C1C362
names: Subcellular Location Annotation
messages: Membrane

2494701:FY206 RS06525
gene id: 2494701:FY206_RS06525
uniprot id: A0A5C1BWX3
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

2494701:FY206 RS01050
gene id: 2494701:FY206_RS01050
uniprot id: A0A5C1BU25
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

2494701:FY206 RS01240
gene id: 2494701:FY206_RS01240
uniprot id: A0A5C1BUA1
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

2494701:FY206 RS23060
gene id: 2494701:FY206_RS23060
uniprot id: A0A5C1C577
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CopD family.
messages: Cell inner membrane
messages: Involved in copper resistance. Appears to be involved in copper uptake.
messages: Membrane

2494701:FY206 RS20945
gene id: 2494701:FY206_RS20945
uniprot id: A0A5C1C4I1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

2494701:FY206 RS17720
gene id: 2494701:FY206_RS17720
uniprot id: A0A5C1C336
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Monomer.

2494701:FY206 RS17930
gene id: 2494701:FY206_RS17930
uniprot id: A0A5C1C2N9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

2494701:FY206 RS06460
gene id: 2494701:FY206_RS06460
uniprot id: A0A5C1BWU4
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

2494701:FY206 RS00740
gene id: 2494701:FY206_RS00740
uniprot id: A0A5C1BTV5
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

2494701:FY206 RS15770
gene id: 2494701:FY206_RS15770
uniprot id: A0A5C1C1J6
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.

2494701:FY206 RS01610
gene id: 2494701:FY206_RS01610
uniprot id: A0A5C1BUD9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. DnaB subfamily.
messages: Homohexamer.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins.

2494701:FY206 RS07575
gene id: 2494701:FY206_RS07575
uniprot id: A0A5C1BXA7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Basic amino acid/polyamine antiporter (APA) (TC 2.A.3.2) family.
messages: Catalyzes both the uptake and excretion of putrescine. The uptake of putrescine is dependent on the membrane potential and the excretion involves putrescine-ornithine antiporter activity.
messages: Cell inner membrane
messages: Membrane

2494701:FY206 RS18205
gene id: 2494701:FY206_RS18205
uniprot id: A0A5C1C4I5
names: Similarity
messages: Belongs to the YfgM family.

2494701:FY206 RS24020
gene id: 2494701:FY206_RS24020
uniprot id: A0A5C1C5N7
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

2494701:FY206 RS23985
gene id: 2494701:FY206_RS23985
uniprot id: A0A5C1C7B3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MenA family. Type 1 subfamily.
messages: Cell membrane
messages: Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK).
messages: Membrane

2494701:FY206 RS04580
gene id: 2494701:FY206_RS04580
uniprot id: A0A5C1BVZ2
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

2494701:FY206 RS19515
gene id: 2494701:FY206_RS19515
uniprot id: A0A5C1C3X8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase with a broad substrate specificity as it can dephosphorylate various ribo- and deoxyribonucleoside 5'-monophosphates and ribonucleoside 3'-monophosphates with highest affinity to 3'-AMP. Also hydrolyzes polyphosphate (exopolyphosphatase activity) with the preference for short-chain-length substrates (P20-25). Might be involved in the regulation of dNTP and NTP pools, and in the turnover of 3'-mononucleotides produced by numerous intracellular RNases (T1, T2, and F) during the degradation of various RNAs.

2494701:FY206 RS00130
gene id: 2494701:FY206_RS00130
uniprot id: A0A5C1BTL8
names: Subcellular Location Annotation
messages: Membrane

2494701:FY206 RS15805
gene id: 2494701:FY206_RS15805
uniprot id: A0A5C1C263
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2494701:FY206 RS06900
gene id: 2494701:FY206_RS06900
uniprot id: A0A5C1BXF4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2494701:FY206 RS09825
gene id: 2494701:FY206_RS09825
uniprot id: A0A5C1BYI9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

2494701:FY206 RS02650
gene id: 2494701:FY206_RS02650
uniprot id: A0A5C1BUV8
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

2494701:FY206 RS24490
gene id: 2494701:FY206_RS24490
uniprot id: A0A5C1C6X4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.

2494701:FY206 RS02285
gene id: 2494701:FY206_RS02285
uniprot id: A0A5C1C7H4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

2494701:FY206 RS18645
gene id: 2494701:FY206_RS18645
uniprot id: A0A5C1C4Q8
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

2494701:FY206 RS06370
gene id: 2494701:FY206_RS06370
uniprot id: A0A5C1BWU9
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

2494701:FY206 RS14505
gene id: 2494701:FY206_RS14505
uniprot id: A0A5C1C0W7
names: Function
names: Similarity
messages: Belongs to the MinE family.
messages: Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.

2494701:FY206 RS10300
gene id: 2494701:FY206_RS10300
uniprot id: A0A5C1BZ70
names: Similarity
messages: Belongs to the glucose-6-phosphate 1-epimerase family.

2494701:FY206 RS16515
gene id: 2494701:FY206_RS16515
uniprot id: A0A5C1C1X4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BexD/CtrA/VexA family.
messages: Cell outer membrane
messages: Membrane

2494701:FY206 RS10955
gene id: 2494701:FY206_RS10955
uniprot id: A0A5C1BZH2
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family. Monothiol subfamily.
messages: Monothiol glutaredoxin involved in the biogenesis of iron-sulfur clusters.

2494701:FY206 RS24590
gene id: 2494701:FY206_RS24590
uniprot id: A0A5C1C6Z2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Part of the phosphate (Pho) regulon, which plays a key role in phosphate homeostasis. PhoU is essential for the repression of the Pho regulon at high phosphate conditions.

2494701:FY206 RS18835
gene id: 2494701:FY206_RS18835
uniprot id: A0A5C1C4F7
names: Similarity
messages: Belongs to the HPS/KGPDC family. HPS subfamily.

2494701:FY206 RS11015
gene id: 2494701:FY206_RS11015
uniprot id: A0A5C1BZH7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SlyA family.
messages: Homodimer.
messages: Transcription regulator that can specifically activate or repress expression of target genes.

2494701:FY206 RS23030
gene id: 2494701:FY206_RS23030
uniprot id: A0A5C1C574
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Has been proposed to be a redox modulator.
messages: Membrane

2494701:FY206 RS16705
gene id: 2494701:FY206_RS16705
uniprot id: A0A5C1C215
names: Function
names: Similarity
messages: Belongs to the esterase D family.
messages: Serine hydrolase involved in the detoxification of formaldehyde.

2494701:FY206 RS06435
gene id: 2494701:FY206_RS06435
uniprot id: A0A5C1BX42
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
messages: Part of the 50S ribosomal subunit.

2494701:FY206 RS11270
gene id: 2494701:FY206_RS11270
uniprot id: A0A5C1BZM6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNT beta subunit family.
messages: Cell inner membrane
messages: Heterodimer of an alpha and a beta chain.
messages: Membrane
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

2494701:FY206 RS10330
gene id: 2494701:FY206_RS10330
uniprot id: A0A5C1BYW7
names: Similarity
messages: Belongs to the asparaginase 1 family.

2494701:FY206 RS19190
gene id: 2494701:FY206_RS19190
uniprot id: A0A5C1C3G1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

2494701:FY206 RS11325
gene id: 2494701:FY206_RS11325
uniprot id: A0A5C1BZV8
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.

2494701:FY206 RS16110
gene id: 2494701:FY206_RS16110
uniprot id: A0A5C1C1P5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

2494701:FY206 RS12820
gene id: 2494701:FY206_RS12820
uniprot id: A0A5C1C0H2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

2494701:FY206 RS00595
gene id: 2494701:FY206_RS00595
uniprot id: A0A5C1BTX0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

2494701:FY206 RS11575
gene id: 2494701:FY206_RS11575
uniprot id: A0A5C1BZG6
names: Function
names: Similarity
messages: Belongs to the TorD/DmsD family. DmsD subfamily.
messages: Required for biogenesis/assembly of DMSO reductase, but not for the interaction of the DmsA signal peptide with the Tat system. May be part of a chaperone cascade complex that facilitates a folding-maturation pathway for the substrate protein.

2494701:FY206 RS06235
gene id: 2494701:FY206_RS06235
uniprot id: A0A5C1BX12
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron.
messages: Heterooctamer of two A chains, two B chains, two C chains and two D chains.
messages: Membrane

2494701:FY206 RS04765
gene id: 2494701:FY206_RS04765
uniprot id: A0A5C1BW14
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di-trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide.
messages: Homodimer.

2494701:FY206 RS15760
gene id: 2494701:FY206_RS15760
uniprot id: A0A5C1C1T9
names: Subcellular Location Annotation
messages: Cytoplasm

2494701:FY206 RS08825
gene id: 2494701:FY206_RS08825
uniprot id: A0A5C1BYI0
names: Subcellular Location Annotation
messages: Membrane

2494701:FY206 RS17065
gene id: 2494701:FY206_RS17065
uniprot id: A0A5C1C294
names: Function
names: Similarity
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MenH family.
messages: Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC).
messages: Monomer.

2494701:FY206 RS14985
gene id: 2494701:FY206_RS14985
uniprot id: A0A5C1C7V8
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

2494701:FY206 RS08360
gene id: 2494701:FY206_RS08360
uniprot id: A0A5C1BYG1
names: Similarity
messages: Belongs to the flavin oxidoreductase frp family.

2494701:FY206 RS18485
gene id: 2494701:FY206_RS18485
uniprot id: A0A5C1C3F6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate.
messages: Cytoplasm

2494701:FY206 RS02490
gene id: 2494701:FY206_RS02490
uniprot id: A0A5C1BV87
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the calycin superfamily. Lipocalin family.
messages: Cell outer membrane
messages: Homodimer.
messages: Involved in the storage or transport of lipids necessary for membrane maintenance under stressful conditions. Displays a binding preference for lysophospholipids.

2494701:FY206 RS17245
gene id: 2494701:FY206_RS17245
uniprot id: A0A5C1C2J7
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

2494701:FY206 RS17385
gene id: 2494701:FY206_RS17385
uniprot id: A0A5C1C3Q5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase M74 family.
messages: Binds 2 Zn(2+) ions per subunit. Zn(2+) ion 1 is bound in the active site. Zn(2+) ion 2 is bound at the dimer interface by residues from both subunits.
messages: Dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Murein endopeptidase that cleaves the D-alanyl-meso-2,6-diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus.
messages: Periplasm

2494701:FY206 RS16720
gene id: 2494701:FY206_RS16720
uniprot id: A0A5C1C3D8
names: Subcellular Location Annotation
messages: Membrane

2494701:FY206 RS23205
gene id: 2494701:FY206_RS23205
uniprot id: A0A5C1C6W9
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

2494701:FY206 RS08405
gene id: 2494701:FY206_RS08405
uniprot id: A0A5C1BY53
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmC subfamily.
messages: Catalyzes the formation of 5-methyl-uridine at position 747 (m5U747) in 23S rRNA.

2494701:FY206 RS10855
gene id: 2494701:FY206_RS10855
uniprot id: A0A5C1BZ42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

2494701:FY206 RS21565
gene id: 2494701:FY206_RS21565
uniprot id: A0A5C1C626
names: Function
names: Similarity
names: Subunit
messages: Belongs to the serine/threonine dehydratase family.
messages: Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. TdcB also dehydrates serine to yield pyruvate via analogous enamine/imine intermediates.
messages: In the native structure, TdcB is in a dimeric form, whereas in the TdcB-AMP complex, it exists in a tetrameric form (dimer of dimers).

2494701:FY206 RS18210
gene id: 2494701:FY206_RS18210
uniprot id: A0A5C1C437
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

2494701:FY206 RS01025
gene id: 2494701:FY206_RS01025
uniprot id: A0A5C1BU62
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

2494701:FY206 RS18195
gene id: 2494701:FY206_RS18195
uniprot id: A0A5C1C2S9
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

2494701:FY206 RS20365
gene id: 2494701:FY206_RS20365
uniprot id: A0A5C1C496
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

2494701:FY206 RS12020
gene id: 2494701:FY206_RS12020
uniprot id: A0A5C1C0A2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
messages: Cell inner membrane

2494701:FY206 RS12005
gene id: 2494701:FY206_RS12005
uniprot id: A0A5C1BZV0
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

2494701:FY206 RS23655
gene id: 2494701:FY206_RS23655
uniprot id: A0A5C1C5H3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the polysaccharide transport (PST) (TC 2.A.66.2) family.
messages: Cell inner membrane
messages: Mediates the transbilayer movement of Und-PP-GlcNAc-ManNAcA-Fuc4NAc (lipid III) from the inner to the outer leaflet of the cytoplasmic membrane during the assembly of enterobacterial common antigen (ECA).
messages: Membrane
messages: Probably part of a complex composed of WzxE, WzyE and WzzE.

2494701:FY206 RS22715
gene id: 2494701:FY206_RS22715
uniprot id: A0A5C1C4Z1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family.
messages: Monomer.
messages: Specifically catalyzes the dephosphorylation of 2-phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress.

2494701:FY206 RS10965
gene id: 2494701:FY206_RS10965
uniprot id: A0A5C1BZ59
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the glyoxalase I family.
messages: Binds 1 nickel ion per subunit.
messages: Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione.

2494701:FY206 RS00705
gene id: 2494701:FY206_RS00705
uniprot id: A0A5C1BV45
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

2494701:FY206 RS17355
gene id: 2494701:FY206_RS17355
uniprot id: A0A5C1C2Y1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. YfcJ family.
messages: Cell inner membrane
messages: Membrane

2494701:FY206 RS14480
gene id: 2494701:FY206_RS14480
uniprot id: A0A5C1C151
names: Similarity
messages: Belongs to the UPF0260 family.

2494701:FY206 RS09015
gene id: 2494701:FY206_RS09015
uniprot id: A0A5C1C6B2
names: Function
names: Induction
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the SulA family.
messages: By DNA damage, as part of the SOS response.
messages: Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division.
messages: Interacts with FtsZ.
messages: Is rapidly cleaved and degraded by the Lon protease once DNA damage is repaired.

2494701:FY206 RS22885
gene id: 2494701:FY206_RS22885
uniprot id: A0A5C1C5E2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S54 family.
messages: Cell membrane
messages: Membrane
messages: Rhomboid-type serine protease that catalyzes intramembrane proteolysis.

2494701:FY206 RS17660
gene id: 2494701:FY206_RS17660
uniprot id: A0A5C1C3U3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial glucokinase family.
messages: Cytoplasm

2494701:FY206 RS09270
gene id: 2494701:FY206_RS09270
uniprot id: A0A5C1BYT7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

2494701:FY206 RS12195
gene id: 2494701:FY206_RS12195
uniprot id: A0A5C1C0C4
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

2494701:FY206 RS10590
gene id: 2494701:FY206_RS10590
uniprot id: A0A5C1C0D4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Involved in the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (BtuD), two transmembrane proteins (BtuC) and a solute-binding protein (BtuF).

2494701:FY206 RS18470
gene id: 2494701:FY206_RS18470
uniprot id: A0A5C1C3C5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E.
messages: Belongs to the RseA family.
messages: Cell inner membrane
messages: Interacts 1:1 with ECF RNA polymerase sigma-E (RpoE); this inhibits the interaction of sigma-E with the RNA polymerase catalytic core and leads to a decreased expression of sigma-E-regulated genes. Interacts with RseB.

2494701:FY206 RS14205
gene id: 2494701:FY206_RS14205
uniprot id: A0A5C1C0Q7
names: Similarity
messages: Belongs to the RHS family.

2494701:FY206 RS22830
gene id: 2494701:FY206_RS22830
uniprot id: A0A5C1C5G7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell inner membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

2494701:FY206 RS11085
gene id: 2494701:FY206_RS11085
uniprot id: A0A5C1C065
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

2494701:FY206 RS06915
gene id: 2494701:FY206_RS06915
uniprot id: A0A5C1BXD2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

2494701:FY206 RS18795
gene id: 2494701:FY206_RS18795
uniprot id: A0A5C1C3L9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2494701:FY206 RS17890
gene id: 2494701:FY206_RS17890
uniprot id: A0A5C1C2N2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the aerobic coproporphyrinogen-III oxidase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX.

2494701:FY206 RS16965
gene id: 2494701:FY206_RS16965
uniprot id: A0A5C1C268
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RcsD family.
messages: Cell inner membrane
messages: Component of the Rcs signaling system, which controls transcription of numerous genes. RcsD is a phosphotransfer intermediate between the sensor kinase RcsC and the response regulator RcsB. It acquires a phosphoryl group from RcsC and transfers it to RcsB.
messages: Interacts with RcsC and RcsB.
messages: Phosphorylated by RcsC.

2494701:FY206 RS05100
gene id: 2494701:FY206_RS05100
uniprot id: A0A5C1BWE6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Crl family.
messages: Binds to the sigma-S subunit of RNA polymerase, activating expression of sigma-S-regulated genes. Stimulates RNA polymerase holoenzyme formation and may bind to several other sigma factors, such as sigma-70 and sigma-32.
messages: Cytoplasm

2494701:FY206 RS04680
gene id: 2494701:FY206_RS04680
uniprot id: A0A5C1C6E8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HesB/IscA family.
messages: Binds 1 iron-sulfur cluster per subunit.
messages: Homodimer.
messages: Required for insertion of 4Fe-4S clusters for at least IspG.

2494701:FY206 RS02485
gene id: 2494701:FY206_RS02485
uniprot id: A0A5C1BW09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

2494701:FY206 RS20530
gene id: 2494701:FY206_RS20530
uniprot id: A0A5C1C420
names: Similarity
messages: Belongs to the YggT family.

2494701:FY206 RS20810
gene id: 2494701:FY206_RS20810
uniprot id: A0A5C1C4G4
names: Function
names: Similarity
messages: Belongs to the esterase D family.
messages: Serine hydrolase involved in the detoxification of formaldehyde.

2494701:FY206 RS13865
gene id: 2494701:FY206_RS13865
uniprot id: A0A5C1C0W0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase D family. Cardiolipin synthase subfamily. ClsA sub-subfamily.
messages: Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
messages: Cell membrane
messages: Membrane

2494701:FY206 RS00455
gene id: 2494701:FY206_RS00455
uniprot id: A0A5C1BTN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

2494701:FY206 RS07515
gene id: 2494701:FY206_RS07515
uniprot id: A0A5C1BXD6
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

2494701:FY206 RS23260
gene id: 2494701:FY206_RS23260
uniprot id: A0A5C1C6X7
names: Subcellular Location Annotation
messages: Membrane

2494701:FY206 RS06110
gene id: 2494701:FY206_RS06110
uniprot id: A0A5C1BX15
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

2494701:FY206 RS17965
gene id: 2494701:FY206_RS17965
uniprot id: A0A5C1C2W5
names: Subcellular Location Annotation
messages: Membrane

2494701:FY206 RS04040
gene id: 2494701:FY206_RS04040
uniprot id: A0A5C1BVN4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

2494701:FY206 RS17695
gene id: 2494701:FY206_RS17695
uniprot id: A0A5C1C6R8
names: Subcellular Location Annotation
messages: Membrane

2494701:FY206 RS21570
gene id: 2494701:FY206_RS21570
uniprot id: A0A5C1C5W3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2494701:FY206 RS21735
gene id: 2494701:FY206_RS21735
uniprot id: A0A5C1C656
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 2 subfamily.
messages: Cytoplasm
messages: Homotetramer.

2494701:FY206 RS03955
gene id: 2494701:FY206_RS03955
uniprot id: A0A5C1BVR1
names: Similarity
messages: Belongs to the UPF0246 family.

2494701:FY206 RS08915
gene id: 2494701:FY206_RS08915
uniprot id: A0A5C1BYF2
names: Similarity
messages: Belongs to the peptidase M1 family.

2494701:FY206 RS11960
gene id: 2494701:FY206_RS11960
uniprot id: A0A5C1BZY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell outer membrane
messages: Membrane

2494701:FY206 RS23870
gene id: 2494701:FY206_RS23870
uniprot id: A0A5C1C5K3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PEPCase type 1 family.
messages: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
messages: Homotetramer.

2494701:FY206 RS14935
gene id: 2494701:FY206_RS14935
uniprot id: A0A5C1C156
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

2494701:FY206 RS07975
gene id: 2494701:FY206_RS07975
uniprot id: A0A5C1BYS4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

2494701:FY206 RS07825
gene id: 2494701:FY206_RS07825
uniprot id: A0A5C1BYP7
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

2494701:FY206 RS02815
gene id: 2494701:FY206_RS02815
uniprot id: A0A5C1BW67
names: Subcellular Location Annotation
messages: Membrane

2494701:FY206 RS20670
gene id: 2494701:FY206_RS20670
uniprot id: A0A5C1C402
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family.
messages: Cell membrane
messages: Membrane

2494701:FY206 RS11165
gene id: 2494701:FY206_RS11165
uniprot id: A0A5C1BZK6
names: Subcellular Location Annotation
messages: Membrane

2494701:FY206 RS08530
gene id: 2494701:FY206_RS08530
uniprot id: A0A5C1BY12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP M family.
messages: Cell inner membrane
messages: Membrane

2494701:FY206 RS07725
gene id: 2494701:FY206_RS07725
uniprot id: A0A5C1BXX1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbB/TolQ family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. Required, with TolR, for the proton motive force-dependent activation of TolA and for TolA-Pal interaction.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

2494701:FY206 RS19210
gene id: 2494701:FY206_RS19210
uniprot id: A0A5C1C3C0
names: Function
messages: Required for the expression of anaerobic nitric oxide (NO) reductase, acts as a transcriptional activator for at least the norVW operon. Activation also requires sigma-54.

2494701:FY206 RS21440
gene id: 2494701:FY206_RS21440
uniprot id: A0A5C1C4M9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Has been proposed to be a redox modulator.
messages: Membrane

2494701:FY206 RS18165
gene id: 2494701:FY206_RS18165
uniprot id: A0A5C1C2T8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

2494701:FY206 RS22485
gene id: 2494701:FY206_RS22485
uniprot id: A0A5C1C5Z8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

2494701:FY206 RS21065
gene id: 2494701:FY206_RS21065
uniprot id: A0A5C1C4I0
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

2494701:FY206 RS00585
gene id: 2494701:FY206_RS00585
uniprot id: A0A5C1BTS4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

2494701:FY206 RS08575
gene id: 2494701:FY206_RS08575
uniprot id: A0A5C1BYD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

2494701:FY206 RS19470
gene id: 2494701:FY206_RS19470
uniprot id: A0A5C1C4L0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the UbiD family. YclC subfamily.
messages: Binds 1 prenylated FMN (prenyl-FMN) per subunit.
messages: Involved in the non-oxidative decarboxylation and detoxification of phenolic derivatives.

2494701:FY206 RS22640
gene id: 2494701:FY206_RS22640
uniprot id: A0A5C1C5D5
names: Similarity
messages: Belongs to the UPF0270 family.

2494701:FY206 RS04745
gene id: 2494701:FY206_RS04745
uniprot id: A0A5C1BW84
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

2494701:FY206 RS08930
gene id: 2494701:FY206_RS08930
uniprot id: A0A5C1BYJ8
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the SsuD family.
messages: Catalyzes the desulfonation of aliphatic sulfonates.
messages: FMNH(2) which is absolutely required for this enzymatic reaction, is provided by SsuE.
messages: Homotetramer.

2494701:FY206 RS15830
gene id: 2494701:FY206_RS15830
uniprot id: A0A5C1C2D7
names: Similarity
messages: Belongs to the IucA/IucC family.

2494701:FY206 RS08260
gene id: 2494701:FY206_RS08260
uniprot id: A0A5C1BYE4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

2494701:FY206 RS25170
gene id: 2494701:FY206_RS25170
uniprot id: A0A5C1C787
names: Similarity
messages: Belongs to the GSP E family.

2494701:FY206 RS14975
gene id: 2494701:FY206_RS14975
uniprot id: A0A5C1C2I9
names: Similarity
messages: Belongs to the leucine-binding protein family.

2494701:FY206 RS24540
gene id: 2494701:FY206_RS24540
uniprot id: A0A5C1C6Y3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.

2494701:FY206 RS01190
gene id: 2494701:FY206_RS01190
uniprot id: A0A5C1BVD7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).

2494701:FY206 RS16665
gene id: 2494701:FY206_RS16665
uniprot id: A0A5C1C7D5
names: Similarity
messages: Belongs to the glutamine synthetase family.

2494701:FY206 RS10625
gene id: 2494701:FY206_RS10625
uniprot id: A0A5C1BZ04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

2494701:FY206 RS01615
gene id: 2494701:FY206_RS01615
uniprot id: A0A5C1BUH5
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

2494701:FY206 RS09875
gene id: 2494701:FY206_RS09875
uniprot id: A0A5C1BYN1
names: Subcellular Location Annotation
messages: Membrane

2494701:FY206 RS10435
gene id: 2494701:FY206_RS10435
uniprot id: A0A5C1BZ39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CpxP/Spy family.
messages: Periplasm

2494701:FY206 RS02535
gene id: 2494701:FY206_RS02535
uniprot id: A0A5C1BUU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

2494701:FY206 RS01635
gene id: 2494701:FY206_RS01635
uniprot id: A0A5C1BUI4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

2494701:FY206 RS19250
gene id: 2494701:FY206_RS19250
uniprot id: A0A5C1C4H3
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

2494701:FY206 RS11645
gene id: 2494701:FY206_RS11645
uniprot id: A0A5C1BZS6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

2494701:FY206 RS04895
gene id: 2494701:FY206_RS04895
uniprot id: A0A5C1BW53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gmhB family.
messages: Cytoplasm

2494701:FY206 RS00480
gene id: 2494701:FY206_RS00480
uniprot id: A0A5C1BTQ1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

2494701:FY206 RS12145
gene id: 2494701:FY206_RS12145
uniprot id: A0A5C1C084
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

2494701:FY206 RS04760
gene id: 2494701:FY206_RS04760
uniprot id: A0A5C1BW87
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Homodimer.

2494701:FY206 RS19535
gene id: 2494701:FY206_RS19535
uniprot id: A0A5C1C3G2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsB family.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

2494701:FY206 RS16135
gene id: 2494701:FY206_RS16135
uniprot id: A0A5C1C256
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

2494701:FY206 RS23670
gene id: 2494701:FY206_RS23670
uniprot id: A0A5C1C5S8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. WecC subfamily.
messages: Catalyzes the four-electron oxidation of UDP-N-acetyl-D-mannosamine (UDP-ManNAc), reducing NAD(+) and releasing UDP-N-acetylmannosaminuronic acid (UDP-ManNAcA).
messages: Homodimer.

2494701:FY206 RS12870
gene id: 2494701:FY206_RS12870
uniprot id: A0A5C1C005
names: Function
names: Similarity
messages: Although this protein associates with the 30S subunit of the ribosome it is not considered to be a bona fide ribosomal protein.
messages: Belongs to the SRA family.

2494701:FY206 RS11485
gene id: 2494701:FY206_RS11485
uniprot id: A0A5C1BZG7
names: Similarity
messages: Belongs to the GST superfamily.

2494701:FY206 RS04035
gene id: 2494701:FY206_RS04035
uniprot id: A0A5C1BVN3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.
messages: Homodimer.

2494701:FY206 RS00775
gene id: 2494701:FY206_RS00775
uniprot id: A0A5C1BU72
names: Subcellular Location Annotation
names: Subunit
messages: Cell inner membrane
messages: Homodimer.
messages: Membrane

2494701:FY206 RS21380
gene id: 2494701:FY206_RS21380
uniprot id: A0A5C1C5F0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DeoC/FbaB aldolase family.
messages: Cytoplasm
messages: Homodecamer.
messages: Involved in the degradation of phospho-AI-2, thereby terminating induction of the lsr operon and closing the AI-2 signaling cycle. Catalyzes the transfer of an acetyl moiety from 3-hydroxy-5-phosphonooxypentane-2,4-dione to CoA to form glycerone phosphate and acetyl-CoA.

2494701:FY206 RS01575
gene id: 2494701:FY206_RS01575
uniprot id: A0A5C1C6C6
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

2494701:FY206 RS22020
gene id: 2494701:FY206_RS22020
uniprot id: A0A5C1C4Z2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

2494701:FY206 RS17815
gene id: 2494701:FY206_RS17815
uniprot id: A0A5C1C2K8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

2494701:FY206 RS17000
gene id: 2494701:FY206_RS17000
uniprot id: A0A5C1C2R3
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

2494701:FY206 RS08025
gene id: 2494701:FY206_RS08025
uniprot id: A0A5C1BYT3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. RhlE subfamily.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in ribosome assembly. Has RNA-dependent ATPase activity and unwinds double-stranded RNA.

2494701:FY206 RS07605
gene id: 2494701:FY206_RS07605
uniprot id: A0A5C1BY24
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system and for the release of the potassium ions to the cytoplasm.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

2494701:FY206 RS11310
gene id: 2494701:FY206_RS11310
uniprot id: A0A5C1BZM2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2494701:FY206 RS11210
gene id: 2494701:FY206_RS11210
uniprot id: A0A5C1BZK4
names: Cofactor
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 1 family.
messages: Binds 1 zinc ion per subunit.

2494701:FY206 RS21960
gene id: 2494701:FY206_RS21960
uniprot id: A0A5C1C523
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

2494701:FY206 RS03665
gene id: 2494701:FY206_RS03665
uniprot id: A0A5C1BVR4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThrE exporter (TC 2.A.79) family.
messages: Cell inner membrane
messages: Involved in succinate export with YjjP. Both proteins are required for export.
messages: Membrane
messages: The transporter is composed of YjjB and YjjP.

2494701:FY206 RS24580
gene id: 2494701:FY206_RS24580
uniprot id: A0A5C1C5X9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Membrane

2494701:FY206 RS09820
gene id: 2494701:FY206_RS09820
uniprot id: A0A5C1BYL8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod.

2494701:FY206 RS10490
gene id: 2494701:FY206_RS10490
uniprot id: A0A5C1BZ73
names: Function
names: Similarity
messages: Belongs to the catalase family. HPII subfamily.
messages: Serves to protect cells from the toxic effects of hydrogen peroxide.

2494701:FY206 RS07700
gene id: 2494701:FY206_RS07700
uniprot id: A0A5C1C7X4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell inner membrane
messages: Membrane

2494701:FY206 RS24705
gene id: 2494701:FY206_RS24705
uniprot id: A0A5C1C6Y2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2494701:FY206 RS12930
gene id: 2494701:FY206_RS12930
uniprot id: A0A5C1C0F9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the formate dehydrogenase gamma subunit family.
messages: Membrane

2494701:FY206 RS02530
gene id: 2494701:FY206_RS02530
uniprot id: A0A5C1BUW9
names: Subcellular Location Annotation
messages: Membrane

2494701:FY206 RS08745
gene id: 2494701:FY206_RS08745
uniprot id: A0A5C1BYF7
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

2494701:FY206 RS19620
gene id: 2494701:FY206_RS19620
uniprot id: A0A5C1C4N5
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2494701:FY206 RS16750
gene id: 2494701:FY206_RS16750
uniprot id: A0A5C1C2D0
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II FruAB PTS system is involved in fructose transport.

2494701:FY206 RS22085
gene id: 2494701:FY206_RS22085
uniprot id: A0A5C1C544
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
messages: Cell membrane
messages: Forms an efflux pump with AaeB.

2494701:FY206 RS13915
gene id: 2494701:FY206_RS13915
uniprot id: A0A5C1C0W8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.

2494701:FY206 RS15555
gene id: 2494701:FY206_RS15555
uniprot id: A0A5C1C1G5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sigma-70 factor family. FliA subfamily.
messages: Cytoplasm
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes.

2494701:FY206 RS12515
gene id: 2494701:FY206_RS12515
uniprot id: A0A5C1C0I4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2494701:FY206 RS16825
gene id: 2494701:FY206_RS16825
uniprot id: A0A5C1C231
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell inner membrane
messages: Membrane

2494701:FY206 RS02510
gene id: 2494701:FY206_RS02510
uniprot id: A0A5C1C606
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FrdC family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of an enzyme complex containing four subunits: a flavoprotein (FrdA), an iron-sulfur protein (FrdB), and two hydrophobic anchor proteins (FrdC and FrdD).
messages: Two distinct, membrane-bound, FAD-containing enzymes are responsible for the catalysis of fumarate and succinate interconversion; fumarate reductase is used in anaerobic growth, and succinate dehydrogenase is used in aerobic growth. Anchors the catalytic components of the fumarate reductase complex to the cell inner membrane, binds quinones.

2494701:FY206 RS04525
gene id: 2494701:FY206_RS04525
uniprot id: A0A5C1BVY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

2494701:FY206 RS13660
gene id: 2494701:FY206_RS13660
uniprot id: A0A5C1C0W9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

2494701:FY206 RS23415
gene id: 2494701:FY206_RS23415
uniprot id: A0A5C1C5D6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. Thiolase family.
messages: Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed.
messages: Cytoplasm
messages: Heterotetramer of two alpha chains (FadB) and two beta chains (FadA).

2494701:FY206 RS23450
gene id: 2494701:FY206_RS23450
uniprot id: A0A5C1C6Y1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

2494701:FY206 RS24575
gene id: 2494701:FY206_RS24575
uniprot id: A0A5C1C6A6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

2494701:FY206 RS00745
gene id: 2494701:FY206_RS00745
uniprot id: A0A5C1BTV7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.
messages: Catalyzes the conversion of L-lactate to pyruvate. Is coupled to the respiratory chain.
messages: Cell membrane

2494701:FY206 RS05610
gene id: 2494701:FY206_RS05610
uniprot id: A0A5C1BWI5
names: Similarity
messages: Belongs to the antirestriction protein family.

2494701:FY206 RS18155
gene id: 2494701:FY206_RS18155
uniprot id: A0A5C1C4H8
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

2494701:FY206 RS24280
gene id: 2494701:FY206_RS24280
uniprot id: A0A5C1C5Z2
names: Function
names: Similarity
messages: Belongs to the HIBADH-related family. 3-sulfolactaldehyde reductase subfamily.
messages: Reduces 3-sulfolactaldehyde (SLA) to 2,3-dihydroxypropane 1-sulfonate (DHPS).

2494701:FY206 RS11385
gene id: 2494701:FY206_RS11385
uniprot id: A0A5C1BZF2
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

2494701:FY206 RS07835
gene id: 2494701:FY206_RS07835
uniprot id: A0A5C1BXI1
names: Similarity
messages: Belongs to the ModE family.

2494701:FY206 RS09580
gene id: 2494701:FY206_RS09580
uniprot id: A0A5C1BYF4
names: Function
messages: May be involved in the biogenesis of curli organelles.

2494701:FY206 RS19860
gene id: 2494701:FY206_RS19860
uniprot id: A0A5C1C3M8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Cell membrane
messages: In the C-terminal section; belongs to the ATP-dependent AMP-binding enzyme family.
messages: In the N-terminal section; belongs to the 2-acyl-GPE acetyltransferase family.
messages: Plays a role in lysophospholipid acylation. Transfers fatty acids to the 1-position via an enzyme-bound acyl-ACP intermediate in the presence of ATP and magnesium. Its physiological function is to regenerate phosphatidylethanolamine from 2-acyl-glycero-3-phosphoethanolamine (2-acyl-GPE) formed by transacylation reactions or degradation by phospholipase A1.

2494701:FY206 RS02925
gene id: 2494701:FY206_RS02925
uniprot id: A0A5C1BVG4
names: Similarity
messages: Belongs to the UPF0307 family.

2494701:FY206 RS11980
gene id: 2494701:FY206_RS11980
uniprot id: A0A5C1BZP5
names: Function
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
messages: Catalyzes the oxidative phosphorylation of glyceraldehyde 3-phosphate (G3P) to 1,3-bisphosphoglycerate (BPG) using the cofactor NAD. The first reaction step involves the formation of a hemiacetal intermediate between G3P and a cysteine residue, and this hemiacetal intermediate is then oxidized to a thioester, with concomitant reduction of NAD to NADH. The reduced NADH is then exchanged with the second NAD, and the thioester is attacked by a nucleophilic inorganic phosphate to produce BPG.

2494701:FY206 RS03945
gene id: 2494701:FY206_RS03945
uniprot id: A0A5C1BW83
names: Similarity
messages: Belongs to the threonine synthase family.

2494701:FY206 RS08385
gene id: 2494701:FY206_RS08385
uniprot id: A0A5C1BZ01
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
messages: Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD).

2494701:FY206 RS08905
gene id: 2494701:FY206_RS08905
uniprot id: A0A5C1BY45
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

2494701:FY206 RS13940
gene id: 2494701:FY206_RS13940
uniprot id: A0A5C1C0Q8
names: Similarity
messages: Belongs to the UPF0225 family.

2494701:FY206 RS20330
gene id: 2494701:FY206_RS20330
uniprot id: A0A5C1C5H5
names: Similarity
messages: Belongs to the UbiH/COQ6 family.

2494701:FY206 RS13390
gene id: 2494701:FY206_RS13390
uniprot id: A0A5C1C6H3
names: Similarity
messages: Belongs to the peptidase C56 family.

2494701:FY206 RS17145
gene id: 2494701:FY206_RS17145
uniprot id: A0A5C1C2H9
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

2494701:FY206 RS13150
gene id: 2494701:FY206_RS13150
uniprot id: A0A5C1C0W4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2494701:FY206 RS22735
gene id: 2494701:FY206_RS22735
uniprot id: A0A5C1C5B5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm

2494701:FY206 RS16240
gene id: 2494701:FY206_RS16240
uniprot id: A0A5C1C276
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 2 family.

2494701:FY206 RS14710
gene id: 2494701:FY206_RS14710
uniprot id: A0A5C1C1M8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

2494701:FY206 RS04355
gene id: 2494701:FY206_RS04355
uniprot id: A0A5C1BW88
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

2494701:FY206 RS14540
gene id: 2494701:FY206_RS14540
uniprot id: A0A5C1C1K0
names: Similarity
messages: Belongs to the UPF0181 family.

2494701:FY206 RS01535
gene id: 2494701:FY206_RS01535
uniprot id: A0A5C1BUM1
names: Similarity
messages: Belongs to the pirin family.

2494701:FY206 RS05980
gene id: 2494701:FY206_RS05980
uniprot id: A0A5C1BX78
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

2494701:FY206 RS08695
gene id: 2494701:FY206_RS08695
uniprot id: A0A5C1BYE8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L/F-transferase family.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.

2494701:FY206 RS12330
gene id: 2494701:FY206_RS12330
uniprot id: A0A5C1C0T9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Membrane

2494701:FY206 RS16855
gene id: 2494701:FY206_RS16855
uniprot id: A0A5C1C245
names: Similarity
messages: To H.influenzae HI_0842.

2494701:FY206 RS21680
gene id: 2494701:FY206_RS21680
uniprot id: A0A5C1C5Y4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. DeaD/CsdA subfamily.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation.

2494701:FY206 RS22420
gene id: 2494701:FY206_RS22420
uniprot id: A0A5C1C558
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

2494701:FY206 RS09065
gene id: 2494701:FY206_RS09065
uniprot id: A0A5C1BY74
names: Similarity
messages: Belongs to the acylphosphatase family.

2494701:FY206 RS19820
gene id: 2494701:FY206_RS19820
uniprot id: A0A5C1C4Y4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

2494701:FY206 RS08330
gene id: 2494701:FY206_RS08330
uniprot id: A0A5C1BXP7
names: Similarity
messages: Belongs to the ArsC family.

2494701:FY206 RS18220
gene id: 2494701:FY206_RS18220
uniprot id: A0A5C1C378
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RodZ family.
messages: Cell inner membrane
messages: Cytoskeletal protein that is involved in cell-shape control through regulation of the length of the long axis.
messages: The helix-turn-helix (HTH) motif in the cytoplasmic domain of the N-terminus is involved in the formation of spirals to maintain the rigid rod shape. As this protein is anchored in the cytoplasmic membrane, the HTH motif may contribute to protein-protein interactions to form the RodZ helix, which is localized beneath the cytoplasmic membrane. The C-terminal domain may be critical for determination of the rod shape by probably interacting with enzymes required for synthesis of the peptidoglycan layer, including PBPs in the periplasm.

2494701:FY206 RS13295
gene id: 2494701:FY206_RS13295
uniprot id: A0A5C1C180
names: Cofactor
names: Similarity
messages: Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.
messages: Binds 3 [4Fe-4S] clusters per subunit.

2494701:FY206 RS05935
gene id: 2494701:FY206_RS05935
uniprot id: A0A5C1BWV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2494701:FY206 RS03650
gene id: 2494701:FY206_RS03650
uniprot id: A0A5C1BVF1
names: Similarity
messages: Belongs to the OsmC/Ohr family.

2494701:FY206 RS07685
gene id: 2494701:FY206_RS07685
uniprot id: A0A5C1BYM9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

2494701:FY206 RS06555
gene id: 2494701:FY206_RS06555
uniprot id: A0A5C1BWW9
names: Subcellular Location Annotation
messages: Membrane

2494701:FY206 RS07865
gene id: 2494701:FY206_RS07865
uniprot id: A0A5C1BXN2
names: Function
names: Similarity
messages: Belongs to the cycloisomerase 2 family.
messages: Catalyzes the hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

2494701:FY206 RS22395
gene id: 2494701:FY206_RS22395
uniprot id: A0A5C1C4T5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

2494701:FY206 RS21305
gene id: 2494701:FY206_RS21305
uniprot id: A0A5C1C5R5
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

2494701:FY206 RS13305
gene id: 2494701:FY206_RS13305
uniprot id: A0A5C1C1N0
names: Similarity
messages: Belongs to the Gfa family.

2494701:FY206 RS22620
gene id: 2494701:FY206_RS22620
uniprot id: A0A5C1C6F3
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MdcC family.
messages: Covalently binds the prosthetic group of malonate decarboxylase.
messages: Cytoplasm
messages: Subunit of malonate decarboxylase, it is an acyl carrier protein to which acetyl and malonyl thioester residues are bound via a 2'-(5''-phosphoribosyl)-3'-dephospho-CoA prosthetic group and turn over during the catalytic mechanism.

2494701:FY206 RS23720
gene id: 2494701:FY206_RS23720
uniprot id: A0A5C1C6L6
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2494701:FY206 RS09575
gene id: 2494701:FY206_RS09575
uniprot id: A0A5C1BYU9
names: Function
messages: May be involved in the biogenesis of curli organelles.

2494701:FY206 RS21015
gene id: 2494701:FY206_RS21015
uniprot id: A0A5C1C6H7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fimbrial export usher family.
messages: Cell outer membrane
messages: Membrane

2494701:FY206 RS22980
gene id: 2494701:FY206_RS22980
uniprot id: A0A5C1C6S0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 83 family.
messages: Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

2494701:FY206 RS02860
gene id: 2494701:FY206_RS02860
uniprot id: A0A5C1BV25
names: Subcellular Location Annotation
messages: Membrane

2494701:FY206 RS06170
gene id: 2494701:FY206_RS06170
uniprot id: A0A5C1BWS8
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

2494701:FY206 RS22075
gene id: 2494701:FY206_RS22075
uniprot id: A0A5C1C503
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

2494701:FY206 RS08995
gene id: 2494701:FY206_RS08995
uniprot id: A0A5C1BY28
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thioester dehydratase family. FabA subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP. Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length.

2494701:FY206 RS14805
gene id: 2494701:FY206_RS14805
uniprot id: A0A5C1C1A3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

2494701:FY206 RS18490
gene id: 2494701:FY206_RS18490
uniprot id: A0A5C1C462
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. tRNA (adenine-N(6)-)-methyltransferase family.
messages: Cytoplasm
messages: Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC).

2494701:FY206 RS04150
gene id: 2494701:FY206_RS04150
uniprot id: A0A5C1BVQ5
names: Similarity
messages: Belongs to the ribulokinase family.

2494701:FY206 RS13910
gene id: 2494701:FY206_RS13910
uniprot id: A0A5C1C100
names: Similarity
messages: In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
messages: In the N-terminal section; belongs to the aldehyde dehydrogenase family.

2494701:FY206 RS10930
gene id: 2494701:FY206_RS10930
uniprot id: A0A5C1C0J1
names: Domain
names: Function
names: Subunit
messages: Consists of two structural and functional domains: an N-terminal DNA-binding domain, approximately the first 60 residues, and a larger C-terminal domain, approximately 280 residues, which imparts the function of corepressor binding and oligomerization.
messages: Homodimer.
messages: Is the main repressor of the genes involved in the de novo synthesis of purine nucleotides, regulating purB, purC, purEK, purF, purHD, purL, purMN and guaBA expression. PurR is allosterically activated to bind its cognate DNA by binding the purine corepressors, hypoxanthine or guanine, thereby effecting transcription repression.

2494701:FY206 RS12345
gene id: 2494701:FY206_RS12345
uniprot id: A0A5C1C096
names: Similarity
messages: Belongs to the PhzF family.

2494701:FY206 RS21155
gene id: 2494701:FY206_RS21155
uniprot id: A0A5C1C5W2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. TDG/mug family.
messages: Binds DNA as a monomer.
messages: Cytoplasm
messages: Excises ethenocytosine and uracil, which can arise by alkylation or deamination of cytosine, respectively, from the corresponding mispairs with guanine in ds-DNA. It is capable of hydrolyzing the carbon-nitrogen bond between the sugar-phosphate backbone of the DNA and the mispaired base. The complementary strand guanine functions in substrate recognition. Required for DNA damage lesion repair in stationary-phase cells.

2494701:FY206 RS17830
gene id: 2494701:FY206_RS17830
uniprot id: A0A5C1C3Y8
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

2494701:FY206 RS12095
gene id: 2494701:FY206_RS12095
uniprot id: A0A5C1C073
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Cell inner membrane
messages: Membrane

2494701:FY206 RS17415
gene id: 2494701:FY206_RS17415
uniprot id: A0A5C1C2R0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. Thiolase family.
messages: Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed.
messages: Cytoplasm
messages: Heterotetramer of two alpha chains (FadJ) and two beta chains (FadI).

2494701:FY206 RS11755
gene id: 2494701:FY206_RS11755
uniprot id: A0A5C1BZU7
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

2494701:FY206 RS06270
gene id: 2494701:FY206_RS06270
uniprot id: A0A5C1BWX5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

2494701:FY206 RS06640
gene id: 2494701:FY206_RS06640
uniprot id: A0A5C1BXK8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.

2494701:FY206 RS04070
gene id: 2494701:FY206_RS04070
uniprot id: A0A5C1BVN7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. KefC subfamily.
messages: Cell inner membrane
messages: Homodimer. Interacts with the regulatory subunit KefF.
messages: Pore-forming subunit of a potassium efflux system that confers protection against electrophiles. Catalyzes K(+)/H(+) antiport.

2494701:FY206 RS20480
gene id: 2494701:FY206_RS20480
uniprot id: A0A5C1C4B5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

2494701:FY206 RS18440
gene id: 2494701:FY206_RS18440
uniprot id: A0A5C1C380
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

2494701:FY206 RS03835
gene id: 2494701:FY206_RS03835
uniprot id: A0A5C1BW61
names: Similarity
messages: Belongs to the Smp family.

2494701:FY206 RS19040
gene id: 2494701:FY206_RS19040
uniprot id: A0A5C1C395
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
messages: Tetramer of two alpha and two beta subunits.

2494701:FY206 RS14465
gene id: 2494701:FY206_RS14465
uniprot id: A0A5C1C266
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Homodimer.
messages: Multifunctional regulator of fatty acid metabolism.

2494701:FY206 RS22180
gene id: 2494701:FY206_RS22180
uniprot id: A0A5C1C7L9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

2494701:FY206 RS20255
gene id: 2494701:FY206_RS20255
uniprot id: A0A5C1C3Z8
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD, in which XerC interacts with XerD via its C-terminal region, XerD interacts with XerC via its C-terminal region and so on.
messages: FtsK may regulate the catalytic switch between XerC and XerD in the heterotetrameric complex during the two steps of the recombination process.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Binds cooperatively to specific DNA consensus sequences that are separated from XerC binding sites by a short central region, forming the heterotetrameric XerC-XerD complex that recombines DNA substrates. The complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. In the complex XerD specifically exchanges the bottom DNA strands.

2494701:FY206 RS21870
gene id: 2494701:FY206_RS21870
uniprot id: A0A5C1C4Z9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate.
messages: Homotetramer.

2494701:FY206 RS21690
gene id: 2494701:FY206_RS21690
uniprot id: A0A5C1C4X7
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cell membrane
messages: Homodimer.
messages: May be involved in cell division.

2494701:FY206 RS22015
gene id: 2494701:FY206_RS22015
uniprot id: A0A5C1C535
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

2494701:FY206 RS14850
gene id: 2494701:FY206_RS14850
uniprot id: A0A5C1C1L0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fimbrial export usher family.
messages: Cell outer membrane

2494701:FY206 RS23660
gene id: 2494701:FY206_RS23660
uniprot id: A0A5C1C5U9
names: Function
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.
messages: Catalyzes the synthesis of dTDP-4-amino-4,6-dideoxy-D-galactose (dTDP-Fuc4N) from dTDP-4-keto-6-deoxy-D-glucose (dTDP-D-Glc4O) and L-glutamate.

2494701:FY206 RS00990
gene id: 2494701:FY206_RS00990
uniprot id: A0A5C1BUW1
names: Subcellular Location Annotation
messages: Cytoplasm

2494701:FY206 RS17190
gene id: 2494701:FY206_RS17190
uniprot id: A0A5C1C2P4
names: Similarity
messages: Belongs to the UPF0304 family.

2494701:FY206 RS00330
gene id: 2494701:FY206_RS00330
uniprot id: A0A5C1BUX4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the calycin superfamily. Lipocalin family.
messages: Cell outer membrane
messages: Homodimer.
messages: Involved in the storage or transport of lipids necessary for membrane maintenance under stressful conditions. Displays a binding preference for lysophospholipids.

2494701:FY206 RS16675
gene id: 2494701:FY206_RS16675
uniprot id: A0A5C1C205
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Galactose/methyl galactoside importer (TC 3.A.1.2.3) family.
messages: Cell inner membrane
messages: Part of the ABC transporter complex MglABC involved in galactose/methyl galactoside import. Responsible for energy coupling to the transport system.
messages: The complex is composed of one ATP-binding protein (MglA), two transmembrane proteins (MglC) and a solute-binding protein (MglB).

2494701:FY206 RS05005
gene id: 2494701:FY206_RS05005
uniprot id: A0A5C1BWF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

2494701:FY206 RS21605
gene id: 2494701:FY206_RS21605
uniprot id: A0A5C1C5J1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LpoA family.
messages: Interacts with PBP1a.
messages: Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1A (PBP1a).

2494701:FY206 RS22055
gene id: 2494701:FY206_RS22055
uniprot id: A0A5C1C4L6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

2494701:FY206 RS04690
gene id: 2494701:FY206_RS04690
uniprot id: A0A5C1BW78
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BtuF family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC.
messages: Periplasm
messages: The complex is composed of two ATP-binding proteins (BtuD), two transmembrane proteins (BtuC) and a solute-binding protein (BtuF).

2494701:FY206 RS24385
gene id: 2494701:FY206_RS24385
uniprot id: A0A5C1C7A9
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MobA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.
messages: Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.

2494701:FY206 RS19030
gene id: 2494701:FY206_RS19030
uniprot id: A0A5C1C4E0
names: Function
names: Similarity
messages: Belongs to the NrdI family.
messages: Probably involved in ribonucleotide reductase function.

2494701:FY206 RS17685
gene id: 2494701:FY206_RS17685
uniprot id: A0A5C1C3U7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NRAMP family.
messages: Cell membrane
messages: H(+)-stimulated, divalent metal cation uptake system.

2494701:FY206 RS23440
gene id: 2494701:FY206_RS23440
uniprot id: A0A5C1C5D8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

2494701:FY206 RS19510
gene id: 2494701:FY206_RS19510
uniprot id: A0A5C1C3K5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
messages: Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.
messages: Cytoplasm

2494701:FY206 RS13060
gene id: 2494701:FY206_RS13060
uniprot id: A0A5C1C057
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxL/LpxM/LpxP family.
messages: Catalyzes the transfer of laurate from lauroyl-acyl carrier protein (ACP) to Kdo(2)-lipid IV(A) to form Kdo(2)-(lauroyl)-lipid IV(A).
messages: Cell inner membrane

2494701:FY206 RS00900
gene id: 2494701:FY206_RS00900
uniprot id: A0A5C1BU42
names: Cofactor
messages: Binds 1 Ca(2+) ion per subunit.

2494701:FY206 RS17055
gene id: 2494701:FY206_RS17055
uniprot id: A0A5C1C3K1
names: Function
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family. MenC type 1 subfamily.
messages: Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 2-succinylbenzoate (OSB).

2494701:FY206 RS18565
gene id: 2494701:FY206_RS18565
uniprot id: A0A5C1C3G4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

2494701:FY206 RS13870
gene id: 2494701:FY206_RS13870
uniprot id: A0A5C1C167
names: Similarity
messages: Belongs to the UPF0263 family.

2494701:FY206 RS17425
gene id: 2494701:FY206_RS17425
uniprot id: A0A5C1C2G0
names: Similarity
messages: Belongs to the UPF0381 family.

2494701:FY206 RS04780
gene id: 2494701:FY206_RS04780
uniprot id: A0A5C1BWG2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamA family.
messages: Cell outer membrane
messages: Part of the Bam complex, which is composed of the outer membrane protein BamA, and four lipoproteins BamB, BamC, BamD and BamE.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. Constitutes, with BamD, the core component of the assembly machinery.

2494701:FY206 RS21590
gene id: 2494701:FY206_RS21590
uniprot id: A0A5C1C4H2
names: Function
names: Similarity
messages: Belongs to the UxaA family.
messages: Catalyzes the dehydration of galactarate to form 5-dehydro-4-deoxy-D-glucarate (5-KDG).

2494701:FY206 RS23120
gene id: 2494701:FY206_RS23120
uniprot id: A0A5C1C5M2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell outer membrane
messages: Membrane

2494701:FY206 RS16585
gene id: 2494701:FY206_RS16585
uniprot id: A0A5C1C2I1
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

2494701:FY206 RS22335
gene id: 2494701:FY206_RS22335
uniprot id: A0A5C1C5V8
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

2494701:FY206 RS21665
gene id: 2494701:FY206_RS21665
uniprot id: A0A5C1C4E9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase U32 family. UbiV subfamily.
messages: Forms an heterodimer with UbiU.
messages: Required for O(2)-independent ubiquinone (coenzyme Q) biosynthesis. Together with UbiU, is essential for the C6-hydroxylation reaction in the oxygen-independent ubiquinone biosynthesis pathway.

2494701:FY206 RS16400
gene id: 2494701:FY206_RS16400
uniprot id: A0A5C1C1U9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the diacylglycerol/lipid kinase family. YegS lipid kinase subfamily.
messages: Binds 1 Mg(2+) ion per subunit. Ca(2+) may be able to substitute.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably phosphorylates lipids; the in vivo substrate is unknown.

2494701:FY206 RS10655
gene id: 2494701:FY206_RS10655
uniprot id: A0A5C1BZA1
names: Function
names: Similarity
messages: Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PSRP subfamily.
messages: Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation.

2494701:FY206 RS12625
gene id: 2494701:FY206_RS12625
uniprot id: A0A5C1C0J9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 13 family.
messages: Cytoplasm

2494701:FY206 RS22730
gene id: 2494701:FY206_RS22730
uniprot id: A0A5C1C5E9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DamX family.
messages: Cell inner membrane
messages: Non-essential cell division protein.
messages: The SPOR domain binds septal peptidoglycans and is required to target DamX to the septal ring.

2494701:FY206 RS07335
gene id: 2494701:FY206_RS07335
uniprot id: A0A5C1BXA3
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

2494701:FY206 RS04395
gene id: 2494701:FY206_RS04395
uniprot id: A0A5C1BVU4
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

2494701:FY206 RS02130
gene id: 2494701:FY206_RS02130
uniprot id: A0A5C1BUR0
names: Similarity
messages: Belongs to the MipA/OmpV family.

2494701:FY206 RS17945
gene id: 2494701:FY206_RS17945
uniprot id: A0A5C1C401
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M20A family. DapE subfamily.
messages: Binds 2 Zn(2+) or Co(2+) ions per subunit.
messages: Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
messages: Homodimer.

2494701:FY206 RS20590
gene id: 2494701:FY206_RS20590
uniprot id: A0A5C1C4D3
names: Similarity
messages: Belongs to the CitG/MdcB family.

2494701:FY206 RS15905
gene id: 2494701:FY206_RS15905
uniprot id: A0A5C1C7C7
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

2494701:FY206 RS11445
gene id: 2494701:FY206_RS11445
uniprot id: A0A5C1C0F2
names: Subcellular Location Annotation
messages: Membrane

2494701:FY206 RS09390
gene id: 2494701:FY206_RS09390
uniprot id: A0A5C1BZF5
names: Function
names: Similarity
messages: Belongs to the non-flavoprotein flavin reductase family. RutF subfamily.
messages: Catalyzes the reduction of FMN to FMNH2 which is used to reduce pyrimidine by RutA via the Rut pathway.

2494701:FY206 RS12280
gene id: 2494701:FY206_RS12280
uniprot id: A0A5C1C183
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

2494701:FY206 RS03670
gene id: 2494701:FY206_RS03670
uniprot id: A0A5C1BVL2
names: Similarity
messages: Belongs to the ThrE exporter (TC 2.A.79) family.

2494701:FY206 RS10560
gene id: 2494701:FY206_RS10560
uniprot id: A0A5C1BZB3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

2494701:FY206 RS08810
gene id: 2494701:FY206_RS08810
uniprot id: A0A5C1BYC8
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS1 family.
messages: Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.

2494701:FY206 RS09215
gene id: 2494701:FY206_RS09215
uniprot id: A0A5C1BYS9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2494701:FY206 RS18690
gene id: 2494701:FY206_RS18690
uniprot id: A0A5C1C327
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

2494701:FY206 RS23970
gene id: 2494701:FY206_RS23970
uniprot id: A0A5C1C5M5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsN family.
messages: Cell inner membrane
messages: Essential cell division protein that activates septal peptidoglycan synthesis and constriction of the cell. Acts on both sides of the membrane, via interaction with FtsA in the cytoplasm and interaction with the FtsQBL complex in the periplasm. These interactions may induce a conformational switch in both FtsA and FtsQBL, leading to septal peptidoglycan synthesis by FtsI and associated synthases.
messages: Interacts with FtsA via its N-terminal cytoplasmic domain.

2494701:FY206 RS24515
gene id: 2494701:FY206_RS24515
uniprot id: A0A5C1C7L1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

2494701:FY206 RS10415
gene id: 2494701:FY206_RS10415
uniprot id: A0A5C1BYY0
names: Function
names: Similarity
messages: Belongs to the arginine N-succinyltransferase family.
messages: Catalyzes the transfer of succinyl-CoA to arginine to produce N(2)-succinylarginine.

2494701:FY206 RS15990
gene id: 2494701:FY206_RS15990
uniprot id: A0A5C1C1M4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Metabolite:H+ Symporter (MHS) family (TC 2.A.1.6) family.
messages: Cell inner membrane
messages: Membrane

2494701:FY206 RS13270
gene id: 2494701:FY206_RS13270
uniprot id: A0A5C1C0Y0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell inner membrane
messages: Membrane

2494701:FY206 RS05885
gene id: 2494701:FY206_RS05885
uniprot id: A0A5C1BWU7
names: Function
names: Similarity
messages: Belongs to the chloramphenicol acetyltransferase family.
messages: This enzyme is an effector of chloramphenicol resistance in bacteria.

2494701:FY206 RS21480
gene id: 2494701:FY206_RS21480
uniprot id: A0A5C1C4F5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell inner membrane
messages: Membrane

2494701:FY206 RS09835
gene id: 2494701:FY206_RS09835
uniprot id: A0A5C1C020
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

2494701:FY206 RS23835
gene id: 2494701:FY206_RS23835
uniprot id: A0A5C1C756
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation.
messages: Cytoplasm

2494701:FY206 RS09550
gene id: 2494701:FY206_RS09550
uniprot id: A0A5C1BYU2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. GhrA subfamily.
messages: Catalyzes the NADPH-dependent reduction of glyoxylate and hydroxypyruvate into glycolate and glycerate, respectively.
messages: Cytoplasm

2494701:FY206 RS23485
gene id: 2494701:FY206_RS23485
uniprot id: A0A5C1C5Q5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 independent methionine synthase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.

2494701:FY206 RS00095
gene id: 2494701:FY206_RS00095
uniprot id: A0A5C1BUD5
names: Cofactor
names: Similarity
messages: Belongs to the glycosyl hydrolase 4 family.
messages: Binds 1 NAD(+) per subunit.

2494701:FY206 RS07080
gene id: 2494701:FY206_RS07080
uniprot id: A0A5C1BXI0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. EntS (TC 2.A.1.38) family.
messages: Cell inner membrane
messages: Component of an export pathway for enterobactin.
messages: Membrane

2494701:FY206 RS06190
gene id: 2494701:FY206_RS06190
uniprot id: A0A5C1BX26
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

2494701:FY206 RS22720
gene id: 2494701:FY206_RS22720
uniprot id: A0A5C1C6M0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

2494701:FY206 RS06480
gene id: 2494701:FY206_RS06480
uniprot id: A0A5C1BX09
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

2494701:FY206 RS22220
gene id: 2494701:FY206_RS22220
uniprot id: A0A5C1C6D2
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

2494701:FY206 RS02115
gene id: 2494701:FY206_RS02115
uniprot id: A0A5C1BVE7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell outer membrane
messages: Membrane

2494701:FY206 RS20460
gene id: 2494701:FY206_RS20460
uniprot id: A0A5C1C4A9
names: Subcellular Location Annotation
messages: Cytoplasm

2494701:FY206 RS19130
gene id: 2494701:FY206_RS19130
uniprot id: A0A5C1C3A7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small RNA(s).
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

2494701:FY206 RS22865
gene id: 2494701:FY206_RS22865
uniprot id: A0A5C1C545
names: Similarity
messages: Belongs to the disproportionating enzyme family.

2494701:FY206 RS00490
gene id: 2494701:FY206_RS00490
uniprot id: A0A5C1BV04
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigB subfamily.
messages: Catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.

2494701:FY206 RS09310
gene id: 2494701:FY206_RS09310
uniprot id: A0A5C1BZ29
names: Similarity
messages: Belongs to the glycosyl hydrolase 42 family.

2494701:FY206 RS04365
gene id: 2494701:FY206_RS04365
uniprot id: A0A5C1BVU9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell inner membrane
messages: Membrane

2494701:FY206 RS14720
gene id: 2494701:FY206_RS14720
uniprot id: A0A5C1C1C7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvB family.
messages: Forms a complex with RuvA.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.

2494701:FY206 RS07035
gene id: 2494701:FY206_RS07035
uniprot id: A0A5C1BXF1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the P-Pant transferase superfamily. EntD family.
messages: EntB, EntD, EntE, and EntF form a multienzyme complex called enterobactin synthase.
messages: Involved in the biosynthesis of the siderophore enterobactin (enterochelin), which is a macrocyclic trimeric lactone of N-(2,3-dihydroxybenzoyl)-serine. The serine trilactone serves as a scaffolding for the three catechol functionalities that provide hexadentate coordination for the tightly ligated iron(2+) atoms. Plays an essential role in the assembly of the enterobactin by catalyzing the transfer of the 4'-phosphopantetheine (Ppant) moiety from coenzyme A to the apo-domains of both EntB (ArCP domain) and EntF (PCP domain) to yield their holo-forms which make them competent for the activation of 2,3-dihydroxybenzoate (DHB) and L-serine, respectively.
messages: Membrane

2494701:FY206 RS01690
gene id: 2494701:FY206_RS01690
uniprot id: A0A5C1BUH1
names: Subcellular Location Annotation
messages: Membrane

2494701:FY206 RS21790
gene id: 2494701:FY206_RS21790
uniprot id: A0A5C1C4G5
names: Subcellular Location Annotation
messages: Cell inner membrane

2494701:FY206 RS12375
gene id: 2494701:FY206_RS12375
uniprot id: A0A5C1BZU2
names: Similarity
messages: Belongs to the DapA family.

2494701:FY206 RS02630
gene id: 2494701:FY206_RS02630
uniprot id: A0A5C1BV40
names: Cofactor
names: Function
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Nitric oxide-sensitive repressor of genes involved in protecting the cell against nitrosative stress. May require iron for activity.

2494701:FY206 RS01470
gene id: 2494701:FY206_RS01470
uniprot id: A0A5C1BUP4
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

2494701:FY206 RS19215
gene id: 2494701:FY206_RS19215
uniprot id: A0A5C1C3B4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Anaerobic nitric oxide reductase; uses NADH to detoxify nitric oxide (NO), protecting several 4Fe-4S NO-sensitive enzymes. Has at least 2 reductase partners, only one of which (NorW, flavorubredoxin reductase) has been identified. NO probably binds to the di-iron center; electrons enter from the NorW at rubredoxin and are transferred sequentially to the FMN center and the di-iron center. Also able to function as an aerobic oxygen reductase.
messages: Binds 1 FMN per monomer.
messages: Binds 3 Fe cations per monomer.
messages: Cytoplasm
messages: Homotetramer.
messages: In the N-terminal section; belongs to the zinc metallo-hydrolase group 3 family.

2494701:FY206 RS01910
gene id: 2494701:FY206_RS01910
uniprot id: A0A5C1BUT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Metabolite:H+ Symporter (MHS) family (TC 2.A.1.6) family.
messages: Cell inner membrane
messages: Membrane

2494701:FY206 RS19825
gene id: 2494701:FY206_RS19825
uniprot id: A0A5C1C3S9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

2494701:FY206 RS08435
gene id: 2494701:FY206_RS08435
uniprot id: A0A5C1BZ09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane

2494701:FY206 RS21795
gene id: 2494701:FY206_RS21795
uniprot id: A0A5C1C664
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

2494701:FY206 RS09625
gene id: 2494701:FY206_RS09625
uniprot id: A0A5C1BYV9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. OpgH subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs).
messages: Membrane

2494701:FY206 RS06350
gene id: 2494701:FY206_RS06350
uniprot id: A0A5C1BWT1
names: Subcellular Location Annotation
messages: Membrane

2494701:FY206 RS06910
gene id: 2494701:FY206_RS06910
uniprot id: A0A5C1BX40
names: Similarity
messages: Belongs to the TPP enzyme family.

2494701:FY206 RS16950
gene id: 2494701:FY206_RS16950
uniprot id: A0A5C1C3I7
names: Cofactor
messages: Binds 1 zinc ion per subunit.

2494701:FY206 RS21340
gene id: 2494701:FY206_RS21340
uniprot id: A0A5C1C487
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the periplasmic pilus chaperone family.
messages: Periplasm

2494701:FY206 RS24465
gene id: 2494701:FY206_RS24465
uniprot id: A0A5C1C7K1
names: Similarity
names: Subunit
messages: Belongs to the ViaA family.
messages: Possible formation of a ternary complex RavA-ViaA-CadA.

2494701:FY206 RS00600
gene id: 2494701:FY206_RS00600
uniprot id: A0A5C1BV24
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

2494701:FY206 RS24130
gene id: 2494701:FY206_RS24130
uniprot id: A0A5C1C766
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the rhamnose mutarotase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the anomeric conversion of L-rhamnose.

2494701:FY206 RS08365
gene id: 2494701:FY206_RS08365
uniprot id: A0A5C1BY85
names: Cofactor
names: Similarity
messages: Belongs to the RimK family.
messages: Binds 2 magnesium or manganese ions per subunit.

2494701:FY206 RS22680
gene id: 2494701:FY206_RS22680
uniprot id: A0A5C1C5E0
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

2494701:FY206 RS04565
gene id: 2494701:FY206_RS04565
uniprot id: A0A5C1BX41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the periplasmic pilus chaperone family.
messages: Periplasm

2494701:FY206 RS24440
gene id: 2494701:FY206_RS24440
uniprot id: A0A5C1C6W7
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

2494701:FY206 RS06530
gene id: 2494701:FY206_RS06530
uniprot id: A0A5C1BX22
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 90 family.
messages: Cytoplasm
messages: Homodimer.
messages: Molecular chaperone. Has ATPase activity.

2494701:FY206 RS07530
gene id: 2494701:FY206_RS07530
uniprot id: A0A5C1BXQ9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

2494701:FY206 RS24300
gene id: 2494701:FY206_RS24300
uniprot id: A0A5C1C658
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:galactoside symporter (TC 2.A.2) family.
messages: Membrane

2494701:FY206 RS09490
gene id: 2494701:FY206_RS09490
uniprot id: A0A5C1C6L8
names: Subcellular Location Annotation
messages: Membrane

2494701:FY206 RS13085
gene id: 2494701:FY206_RS13085
uniprot id: A0A5C1C0L7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane

2494701:FY206 RS08155
gene id: 2494701:FY206_RS08155
uniprot id: A0A5C1BYC1
names: Subcellular Location Annotation
messages: Membrane

2494701:FY206 RS18445
gene id: 2494701:FY206_RS18445
uniprot id: A0A5C1C2Z0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

2494701:FY206 RS21860
gene id: 2494701:FY206_RS21860
uniprot id: A0A5C1C4W2
names: Subcellular Location Annotation
messages: Membrane

2494701:FY206 RS17905
gene id: 2494701:FY206_RS17905
uniprot id: A0A5C1C364
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

2494701:FY206 RS07310
gene id: 2494701:FY206_RS07310
uniprot id: A0A5C1BXQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane

2494701:FY206 RS18310
gene id: 2494701:FY206_RS18310
uniprot id: A0A5C1C452
names: Cofactor
names: Function
messages: Binds 1 [2Fe-2S] cluster.
messages: Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins.

2494701:FY206 RS17845
gene id: 2494701:FY206_RS17845
uniprot id: A0A5C1C2U8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the ABC transporter complex (TC 3.A.1.6.1) involved in sulfate/thiosulfate import.
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

2494701:FY206 RS07165
gene id: 2494701:FY206_RS07165
uniprot id: A0A5C1BX83
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

2494701:FY206 RS10225
gene id: 2494701:FY206_RS10225
uniprot id: A0A5C1BYU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

2494701:FY206 RS12810
gene id: 2494701:FY206_RS12810
uniprot id: A0A5C1C1F6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M15D family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide.

2494701:FY206 RS17155
gene id: 2494701:FY206_RS17155
uniprot id: A0A5C1C3L7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell membrane
messages: NDH-1 is composed of 13 different subunits. Subunits NuoB, CD, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

2494701:FY206 RS06560
gene id: 2494701:FY206_RS06560
uniprot id: A0A5C1BWW3
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

2494701:FY206 RS00730
gene id: 2494701:FY206_RS00730
uniprot id: A0A5C1BUR1
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

2494701:FY206 RS06130
gene id: 2494701:FY206_RS06130
uniprot id: A0A5C1BXB1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

2494701:FY206 RS23750
gene id: 2494701:FY206_RS23750
uniprot id: A0A5C1C746
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

2494701:FY206 RS14590
gene id: 2494701:FY206_RS14590
uniprot id: A0A5C1C0Y3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PqiA family.
messages: Component of a transport pathway that contributes to membrane integrity.
messages: Membrane

2494701:FY206 RS10010
gene id: 2494701:FY206_RS10010
uniprot id: A0A5C1BYW8
names: Similarity
messages: Belongs to the UPF0227 family.

2494701:FY206 RS21910
gene id: 2494701:FY206_RS21910
uniprot id: A0A5C1C4X2
names: Subcellular Location Annotation
messages: Cytoplasm

2494701:FY206 RS14940
gene id: 2494701:FY206_RS14940
uniprot id: A0A5C1C1Z9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DcuA/DcuB transporter (TC 2.A.13.1) family.
messages: Cell inner membrane
messages: Membrane
messages: Responsible for the transport of C4-dicarboxylates.

2494701:FY206 RS15660
gene id: 2494701:FY206_RS15660
uniprot id: A0A5C1C1F7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: Cell inner membrane
messages: FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

2494701:FY206 RS14075
gene id: 2494701:FY206_RS14075
uniprot id: A0A5C1C164
names: Similarity
messages: Belongs to the UPF0162 family.

2494701:FY206 RS08655
gene id: 2494701:FY206_RS08655
uniprot id: A0A5C1BY81
names: Similarity
messages: In the N-terminal section; belongs to the CRISPR-associated nuclease Cas3-HD family.
messages: In the central section; belongs to the CRISPR-associated helicase Cas3 family.

2494701:FY206 RS21760
gene id: 2494701:FY206_RS21760
uniprot id: A0A5C1C4K2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2494701:FY206 RS24060
gene id: 2494701:FY206_RS24060
uniprot id: A0A5C1C6R4
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homotetramer.

2494701:FY206 RS11040
gene id: 2494701:FY206_RS11040
uniprot id: A0A5C1C0L1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
messages: Homodimer.

2494701:FY206 RS20575
gene id: 2494701:FY206_RS20575
uniprot id: A0A5C1C485
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Fe(2+)-trafficking protein family.
messages: Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.
messages: Monomer.

2494701:FY206 RS14005
gene id: 2494701:FY206_RS14005
uniprot id: A0A5C1C1J1
names: Similarity
messages: Belongs to the intimin/invasin family.

2494701:FY206 RS01360
gene id: 2494701:FY206_RS01360
uniprot id: A0A5C1BVG9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family. MalFG subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Part of the ABC transporter complex MalEFGK involved in maltose/maltodextrin import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (MalK), two transmembrane proteins (MalG and MalF) and a solute-binding protein (MalE).

2494701:FY206 RS19650
gene id: 2494701:FY206_RS19650
uniprot id: A0A5C1C3Q2
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family. GlucD subfamily.

2494701:FY206 RS11650
gene id: 2494701:FY206_RS11650
uniprot id: A0A5C1C041
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

2494701:FY206 RS11290
gene id: 2494701:FY206_RS11290
uniprot id: A0A5C1C0C2
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

2494701:FY206 RS22115
gene id: 2494701:FY206_RS22115
uniprot id: A0A5C1C667
names: Similarity
messages: Belongs to the RNase E/G family. RNase G subfamily.

2494701:FY206 RS16095
gene id: 2494701:FY206_RS16095
uniprot id: A0A5C1C2A9
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

2494701:FY206 RS08185
gene id: 2494701:FY206_RS08185
uniprot id: A0A5C1BY30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YkuD family.
messages: Periplasm

2494701:FY206 RS17335
gene id: 2494701:FY206_RS17335
uniprot id: A0A5C1C3P3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.

2494701:FY206 RS05735
gene id: 2494701:FY206_RS05735
uniprot id: A0A5C1BX44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

2494701:FY206 RS15530
gene id: 2494701:FY206_RS15530
uniprot id: A0A5C1C1J0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

2494701:FY206 RS04435
gene id: 2494701:FY206_RS04435
uniprot id: A0A5C1BWH5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TraT lipoprotein family.
messages: Cell outer membrane
messages: Membrane
messages: Responsible for preventing unproductive conjugation between bacteria carrying like plasmids.

2494701:FY206 RS06860
gene id: 2494701:FY206_RS06860
uniprot id: A0A5C1BXC8
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

2494701:FY206 RS09535
gene id: 2494701:FY206_RS09535
uniprot id: A0A5C1BZ64
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2494701:FY206 RS03930
gene id: 2494701:FY206_RS03930
uniprot id: A0A5C1C620
names: Function
names: Similarity
messages: Belongs to the thr operon leader peptide family.
messages: This protein is involved in control of the biosynthesis of threonine.

2494701:FY206 RS20370
gene id: 2494701:FY206_RS20370
uniprot id: A0A5C1C4Z7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose 5-phosphate isomerase family.
messages: Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
messages: Homodimer.

2494701:FY206 RS19010
gene id: 2494701:FY206_RS19010
uniprot id: A0A5C1C392
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AlaE exporter family.
messages: Cell inner membrane
messages: Exports L-alanine.

2494701:FY206 RS16260
gene id: 2494701:FY206_RS16260
uniprot id: A0A5C1C246
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.
messages: Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2494701:FY206 RS01500
gene id: 2494701:FY206_RS01500
uniprot id: A0A5C1BUD1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family. UgpAE subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the binding-protein-dependent transport system for sn-glycerol-3-phosphate; probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (UgpC), two transmembrane proteins (UgpA and UgpE) and a solute-binding protein (UgpB).

2494701:FY206 RS08815
gene id: 2494701:FY206_RS08815
uniprot id: A0A5C1BYR9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

2494701:FY206 RS23975
gene id: 2494701:FY206_RS23975
uniprot id: A0A5C1C5T2
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

2494701:FY206 RS22805
gene id: 2494701:FY206_RS22805
uniprot id: A0A5C1C5D3
names: Subcellular Location Annotation
messages: Cell inner membrane

2494701:FY206 RS03855
gene id: 2494701:FY206_RS03855
uniprot id: A0A5C1BVK4
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.

2494701:FY206 RS22330
gene id: 2494701:FY206_RS22330
uniprot id: A0A5C1C578
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Cytoplasm
messages: Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.

2494701:FY206 RS00835
gene id: 2494701:FY206_RS00835
uniprot id: A0A5C1BUF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:galactoside symporter (TC 2.A.2) family.
messages: Membrane

2494701:FY206 RS10075
gene id: 2494701:FY206_RS10075
uniprot id: A0A5C1BYX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YkuD family.
messages: Periplasm

2494701:FY206 RS21405
gene id: 2494701:FY206_RS21405
uniprot id: A0A5C1C600
names: Similarity
messages: Belongs to the SorC transcriptional regulatory family.

2494701:FY206 RS12670
gene id: 2494701:FY206_RS12670
uniprot id: A0A5C1C0A9
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

2494701:FY206 RS23190
gene id: 2494701:FY206_RS23190
uniprot id: A0A5C1C5A3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein B family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

2494701:FY206 RS01265
gene id: 2494701:FY206_RS01265
uniprot id: A0A5C1BUK5
names: Similarity
messages: Belongs to the malate synthase family.

2494701:FY206 RS19520
gene id: 2494701:FY206_RS19520
uniprot id: A0A5C1C4M0
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruD family.
messages: Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.

2494701:FY206 RS24615
gene id: 2494701:FY206_RS24615
uniprot id: A0A5C1C7F3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2494701:FY206 RS20760
gene id: 2494701:FY206_RS20760
uniprot id: A0A5C1C556
names: Subunit
messages: Monomer.

2494701:FY206 RS01415
gene id: 2494701:FY206_RS01415
uniprot id: A0A5C1BUN1
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. RsmD family.
messages: Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle.

2494701:FY206 RS22315
gene id: 2494701:FY206_RS22315
uniprot id: A0A5C1C573
names: Similarity
messages: Belongs to the DprA/Smf family.

2494701:FY206 RS13480
gene id: 2494701:FY206_RS13480
uniprot id: A0A5C1C0E0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2494701:FY206 RS10680
gene id: 2494701:FY206_RS10680
uniprot id: A0A5C1BZ12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

2494701:FY206 RS16070
gene id: 2494701:FY206_RS16070
uniprot id: A0A5C1C330
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2494701:FY206 RS07985
gene id: 2494701:FY206_RS07985
uniprot id: A0A5C1BXL6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase D family. Cardiolipin synthase subfamily. ClsB sub-subfamily.
messages: Catalyzes the phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
messages: Cell membrane

2494701:FY206 RS22235
gene id: 2494701:FY206_RS22235
uniprot id: A0A5C1C531
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

2494701:FY206 RS22995
gene id: 2494701:FY206_RS22995
uniprot id: A0A5C1C6J8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family.
messages: Catalyzes the transfer of 4-deoxy-4-formamido-L-arabinose from UDP to undecaprenyl phosphate. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.
messages: Cell membrane

2494701:FY206 RS20315
gene id: 2494701:FY206_RS20315
uniprot id: A0A5C1C406
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

2494701:FY206 RS22105
gene id: 2494701:FY206_RS22105
uniprot id: A0A5C1C4M6
names: Function
names: Similarity
messages: Belongs to the peptidase U62 family.
messages: Metalloprotease involved in CcdA degradation. Suppresses the inhibitory activity of the carbon storage regulator (CsrA).

2494701:FY206 RS19685
gene id: 2494701:FY206_RS19685
uniprot id: A0A5C1C3R6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Syd family.
messages: Cell inner membrane
messages: Interacts with the SecY protein in vivo. May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function.

2494701:FY206 RS15690
gene id: 2494701:FY206_RS15690
uniprot id: A0A5C1C1M2
names: Function
names: Similarity
messages: Belongs to the RcsA family.
messages: Component of the Rcs signaling system, which controls transcription of numerous genes. Binds to DNA to regulate expression of genes.

2494701:FY206 RS04145
gene id: 2494701:FY206_RS04145
uniprot id: A0A5C1C730
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the arabinose isomerase family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the conversion of L-arabinose to L-ribulose.
messages: Homohexamer.

2494701:FY206 RS14915
gene id: 2494701:FY206_RS14915
uniprot id: A0A5C1C2H5
names: Function
names: Similarity
messages: Belongs to the trehalose phosphatase family.
messages: Removes the phosphate from trehalose 6-phosphate to produce free trehalose.

2494701:FY206 RS19755
gene id: 2494701:FY206_RS19755
uniprot id: A0A5C1C4X5
names: Function
messages: Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and/or cell division.

2494701:FY206 RS02270
gene id: 2494701:FY206_RS02270
uniprot id: A0A5C1BUT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

2494701:FY206 RS07450
gene id: 2494701:FY206_RS07450
uniprot id: A0A5C1BXC4
names: Similarity
messages: Belongs to the PhoH family.

2494701:FY206 RS10905
gene id: 2494701:FY206_RS10905
uniprot id: A0A5C1BZG3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MdtK subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Multidrug efflux pump that functions probably as a Na(+)/drug antiporter.

2494701:FY206 RS12340
gene id: 2494701:FY206_RS12340
uniprot id: A0A5C1BZT1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. SotB (TC 2.A.1.2) family.
messages: Cell membrane
messages: Involved in the efflux of sugars. The physiological role may be the reduction of the intracellular concentration of toxic sugars or sugar metabolites.
messages: Membrane

2494701:FY206 RS24545
gene id: 2494701:FY206_RS24545
uniprot id: A0A5C1C6A5
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

2494701:FY206 RS14445
gene id: 2494701:FY206_RS14445
uniprot id: A0A5C1C186
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. NhaP2 subfamily.
messages: Cell membrane
messages: K(+)/H(+) antiporter that extrudes potassium in exchange for external protons and maintains the internal concentration of potassium under toxic levels.

2494701:FY206 RS19570
gene id: 2494701:FY206_RS19570
uniprot id: A0A5C1C4M8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Catalyzes the formation of sulfite from phosphoadenosine 5'-phosphosulfate (PAPS) using thioredoxin as an electron donor.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2494701:FY206 RS15825
gene id: 2494701:FY206_RS15825
uniprot id: A0A5C1C1K5
names: Subcellular Location Annotation
messages: Membrane

2494701:FY206 RS06450
gene id: 2494701:FY206_RS06450
uniprot id: A0A5C1BX84
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

2494701:FY206 RS07210
gene id: 2494701:FY206_RS07210
uniprot id: A0A5C1BXN0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acireductone dioxygenase (ARD) family.
messages: Binds 1 Fe(2+) cation per monomer.
messages: Binds 1 nickel ion per monomer.
messages: Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
messages: Monomer.

2494701:FY206 RS07820
gene id: 2494701:FY206_RS07820
uniprot id: A0A5C1BXE7
names: Cofactor
names: Similarity
messages: Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.
messages: Binds 1 Fe cation per subunit.
messages: Binds 1 zinc ion per subunit.

2494701:FY206 RS02430
gene id: 2494701:FY206_RS02430
uniprot id: A0A5C1BVZ8
names: Similarity
messages: Belongs to the class-II fumarase/aspartase family. Aspartase subfamily.

2494701:FY206 RS15820
gene id: 2494701:FY206_RS15820
uniprot id: A0A5C1C1I6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MtfA family.
messages: Cytoplasm
messages: Interacts with Mlc.
messages: Involved in the regulation of ptsG expression by binding and inactivating Mlc.

2494701:FY206 RS16925
gene id: 2494701:FY206_RS16925
uniprot id: A0A5C1C3I0
names: Similarity
messages: Belongs to the MQO family.

2494701:FY206 RS20615
gene id: 2494701:FY206_RS20615
uniprot id: A0A5C1C5M6
names: Function
messages: Acetylation of prosthetic group (2-(5''-phosphoribosyl)-3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase.

2494701:FY206 RS12735
gene id: 2494701:FY206_RS12735
uniprot id: A0A5C1C0I0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbC subfamily.
messages: Periplasm
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process.

2494701:FY206 RS19285
gene id: 2494701:FY206_RS19285
uniprot id: A0A5C1C3M3
names: Subcellular Location Annotation
messages: Membrane

2494701:FY206 RS13570
gene id: 2494701:FY206_RS13570
uniprot id: A0A5C1C1C3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

2494701:FY206 RS12485
gene id: 2494701:FY206_RS12485
uniprot id: A0A5C1C0W3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. Tam family.
messages: Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate.
messages: Cytoplasm

2494701:FY206 RS06625
gene id: 2494701:FY206_RS06625
uniprot id: A0A5C1BWZ5
names: Subcellular Location Annotation
messages: Membrane

2494701:FY206 RS03040
gene id: 2494701:FY206_RS03040
uniprot id: A0A5C1BV39
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

2494701:FY206 RS01130
gene id: 2494701:FY206_RS01130
uniprot id: A0A5C1BU36
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

2494701:FY206 RS08540
gene id: 2494701:FY206_RS08540
uniprot id: A0A5C1BZ26
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family. Chitinase class II subfamily.

2494701:FY206 RS07100
gene id: 2494701:FY206_RS07100
uniprot id: A0A5C1BXT5
names: Cofactor
messages: Binds 1 phosphopantetheine covalently.

2494701:FY206 RS22595
gene id: 2494701:FY206_RS22595
uniprot id: A0A5C1C595
names: Similarity
messages: Belongs to the fabD family.

2494701:FY206 RS10845
gene id: 2494701:FY206_RS10845
uniprot id: A0A5C1C772
names: Function
names: Similarity
messages: Belongs to the FumD family.
messages: In vitro catalyzes the addition of water to fumarate, forming malate. Cannot catalyze the reverse reaction. Cannot use the cis-isomer maleate as substrate.

2494701:FY206 RS00735
gene id: 2494701:FY206_RS00735
uniprot id: A0A5C1BUD0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide.

2494701:FY206 RS24330
gene id: 2494701:FY206_RS24330
uniprot id: A0A5C1C601
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes.

2494701:FY206 RS18610
gene id: 2494701:FY206_RS18610
uniprot id: A0A5C1C3E1
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

2494701:FY206 RS18705
gene id: 2494701:FY206_RS18705
uniprot id: A0A5C1C342
names: Similarity
messages: Belongs to the UPF0125 (RnfH) family.

2494701:FY206 RS20390
gene id: 2494701:FY206_RS20390
uniprot id: A0A5C1C5I7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Cell inner membrane
messages: Homoheptamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.
messages: Membrane

2494701:FY206 RS18425
gene id: 2494701:FY206_RS18425
uniprot id: A0A5C1C349
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

2494701:FY206 RS22005
gene id: 2494701:FY206_RS22005
uniprot id: A0A5C1C694
names: Similarity
messages: Belongs to the GST superfamily. HSP26 family.

2494701:FY206 RS09570
gene id: 2494701:FY206_RS09570
uniprot id: A0A5C1BZI1
names: Function
names: Similarity
messages: Belongs to the CsgG family.
messages: May be involved in the biogenesis of curli organelles.

2494701:FY206 RS04935
gene id: 2494701:FY206_RS04935
uniprot id: A0A5C1BWR2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2494701:FY206 RS20285
gene id: 2494701:FY206_RS20285
uniprot id: A0A5C1C439
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0073 (Hly-III) family.
messages: Membrane

2494701:FY206 RS18515
gene id: 2494701:FY206_RS18515
uniprot id: A0A5C1C495
names: Similarity
messages: Belongs to the thioredoxin family.

2494701:FY206 RS18040
gene id: 2494701:FY206_RS18040
uniprot id: A0A5C1C2Q0
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

2494701:FY206 RS16410
gene id: 2494701:FY206_RS16410
uniprot id: A0A5C1C242
names: Subcellular Location Annotation
messages: Membrane

2494701:FY206 RS03075
gene id: 2494701:FY206_RS03075
uniprot id: A0A5C1BV61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arginine deiminase family.
messages: Cytoplasm

2494701:FY206 RS22320
gene id: 2494701:FY206_RS22320
uniprot id: A0A5C1C539
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

2494701:FY206 RS16740
gene id: 2494701:FY206_RS16740
uniprot id: A0A5C1C2L0
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

2494701:FY206 RS16090
gene id: 2494701:FY206_RS16090
uniprot id: A0A5C1C1X6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.
messages: Homodimer.

2494701:FY206 RS11920
gene id: 2494701:FY206_RS11920
uniprot id: A0A5C1BZX6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2494701:FY206 RS07600
gene id: 2494701:FY206_RS07600
uniprot id: A0A5C1BXR2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpC family.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

2494701:FY206 RS14625
gene id: 2494701:FY206_RS14625
uniprot id: A0A5C1C110
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CopD family.
messages: Cell inner membrane
messages: Involved in copper resistance. Appears to be involved in copper uptake.
messages: Membrane

2494701:FY206 RS07295
gene id: 2494701:FY206_RS07295
uniprot id: A0A5C1BXL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DcuC/DcuD transporter (TC 2.A.61) family.
messages: Membrane

2494701:FY206 RS18030
gene id: 2494701:FY206_RS18030
uniprot id: A0A5C1C3Z1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaA family. HdA subfamily.
messages: Mediates the interaction of DNA replication inititator protein DnaA with DNA polymerase subunit beta sliding clamp (dnaN). Stimulates hydrolysis of ATP-DnaA to ADP-DnaA, rendering DnaA inactive for reinititation, a process called regulatory inhibition of DnaA or RIDA.
messages: The active form seems to be an ADP-bound monomer. Forms the RIDA complex (regulatory inactivation of DnaA) of ATP-DnaA, ADP-Hda and the DNA-loaded beta sliding clamp (dnaN).

2494701:FY206 RS04835
gene id: 2494701:FY206_RS04835
uniprot id: A0A5C1BW45
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

2494701:FY206 RS17975
gene id: 2494701:FY206_RS17975
uniprot id: A0A5C1C3Y3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamC family.
messages: Cell outer membrane
messages: Part of the Bam complex, which is composed of the outer membrane protein BamA, and four lipoproteins BamB, BamC, BamD and BamE.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

2494701:FY206 RS20515
gene id: 2494701:FY206_RS20515
uniprot id: A0A5C1C5B4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

2494701:FY206 RS14700
gene id: 2494701:FY206_RS14700
uniprot id: A0A5C1C6N9
names: Function
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.
messages: Involved in the high-affinity zinc uptake transport system.

2494701:FY206 RS23185
gene id: 2494701:FY206_RS23185
uniprot id: A0A5C1C5L2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family. Pit subfamily.
messages: Membrane

2494701:FY206 RS08390
gene id: 2494701:FY206_RS08390
uniprot id: A0A5C1BY98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2494701:FY206 RS23885
gene id: 2494701:FY206_RS23885
uniprot id: A0A5C1C790
names: Similarity
messages: Belongs to the organic radical-activating enzymes family.

2494701:FY206 RS20740
gene id: 2494701:FY206_RS20740
uniprot id: A0A5C1C4F0
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

2494701:FY206 RS16295
gene id: 2494701:FY206_RS16295
uniprot id: A0A5C1C288
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the etk/wzc family.
messages: Cell inner membrane
messages: Membrane

2494701:FY206 RS07020
gene id: 2494701:FY206_RS07020
uniprot id: A0A5C1BXH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fimbrial export usher family.
messages: Cell outer membrane
messages: Membrane

2494701:FY206 RS14440
gene id: 2494701:FY206_RS14440
uniprot id: A0A5C1C262
names: Similarity
messages: Belongs to the peptidase S66 family.

2494701:FY206 RS00670
gene id: 2494701:FY206_RS00670
uniprot id: A0A5C1BU51
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA.
messages: Homodimer.

2494701:FY206 RS20890
gene id: 2494701:FY206_RS20890
uniprot id: A0A5C1C4G9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.
messages: Cell membrane
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

2494701:FY206 RS21140
gene id: 2494701:FY206_RS21140
uniprot id: A0A5C1C4H6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

2494701:FY206 RS02460
gene id: 2494701:FY206_RS02460
uniprot id: A0A5C1BV63
names: Similarity
messages: Belongs to the radical SAM superfamily. KamA family.

2494701:FY206 RS14420
gene id: 2494701:FY206_RS14420
uniprot id: A0A5C1C0U8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

2494701:FY206 RS17940
gene id: 2494701:FY206_RS17940
uniprot id: A0A5C1C4D9
names: Similarity
messages: Belongs to the ArsC family.

2494701:FY206 RS01125
gene id: 2494701:FY206_RS01125
uniprot id: A0A5C1BU38
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

2494701:FY206 RS22740
gene id: 2494701:FY206_RS22740
uniprot id: A0A5C1C524
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Monomer.

2494701:FY206 RS24095
gene id: 2494701:FY206_RS24095
uniprot id: A0A5C1C619
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L-rhamnose transporter (TC 2.A.7.6) family.
messages: Cell membrane
messages: Uptake of L-rhamnose across the cytoplasmic membrane with the concomitant transport of protons into the cell (symport system).

2494701:FY206 RS15665
gene id: 2494701:FY206_RS15665
uniprot id: A0A5C1C1I1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliN/MopA/SpaO family.
messages: Cell membrane
messages: FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

2494701:FY206 RS21850
gene id: 2494701:FY206_RS21850
uniprot id: A0A5C1C613
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MlaE permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the ABC transporter complex MlaFEDB, which is involved in a phospholipid transport pathway that maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (MlaF), two transmembrane proteins (MlaE), two cytoplasmic solute-binding proteins (MlaB) and six periplasmic solute-binding proteins (MlaD).

2494701:FY206 RS11395
gene id: 2494701:FY206_RS11395
uniprot id: A0A5C1C0E2
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

2494701:FY206 RS19710
gene id: 2494701:FY206_RS19710
uniprot id: A0A5C1C3R1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Xni family.
messages: Binds 1 K(+) per subunit. The potassium ion strongly increases the affinity for DNA.
messages: Binds 2 Mg(2+) per subunit. Only one magnesium ion has a direct interaction with the protein, the other interactions are indirect.
messages: Has flap endonuclease activity. During DNA replication, flap endonucleases cleave the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment.

2494701:FY206 RS06940
gene id: 2494701:FY206_RS06940
uniprot id: A0A5C1BX55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

2494701:FY206 RS02625
gene id: 2494701:FY206_RS02625
uniprot id: A0A5C1BUW3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

2494701:FY206 RS23740
gene id: 2494701:FY206_RS23740
uniprot id: A0A5C1C5Q0
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

2494701:FY206 RS11420
gene id: 2494701:FY206_RS11420
uniprot id: A0A5C1C012
names: Subcellular Location Annotation
messages: Membrane

2494701:FY206 RS21135
gene id: 2494701:FY206_RS21135
uniprot id: A0A5C1C5B8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

2494701:FY206 RS01495
gene id: 2494701:FY206_RS01495
uniprot id: A0A5C1BUS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2494701:FY206 RS07185
gene id: 2494701:FY206_RS07185
uniprot id: A0A5C1BX76
names: Function
names: Similarity
names: Subunit
messages: Belongs to the methylthioribose kinase family.
messages: Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate.
messages: Homodimer.

2494701:FY206 RS16490
gene id: 2494701:FY206_RS16490
uniprot id: A0A5C1C279
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

2494701:FY206 RS09955
gene id: 2494701:FY206_RS09955
uniprot id: A0A5C1BYY4
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

2494701:FY206 RS24255
gene id: 2494701:FY206_RS24255
uniprot id: A0A5C1C5S7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

2494701:FY206 RS20735
gene id: 2494701:FY206_RS20735
uniprot id: A0A5C1C5F1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the exbB/tolQ family.
messages: Cell inner membrane
messages: Involved in the TonB-dependent energy-dependent transport of various receptor-bound substrates. Protects ExbD from proteolytic degradation and functionally stabilizes TonB.
messages: Membrane
messages: The accessory proteins ExbB and ExbD seem to form a complex with TonB.

2494701:FY206 RS14840
gene id: 2494701:FY206_RS14840
uniprot id: A0A5C1C2D5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Cell inner membrane
messages: Membrane

2494701:FY206 RS06210
gene id: 2494701:FY206_RS06210
uniprot id: A0A5C1BX33
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

2494701:FY206 RS13985
gene id: 2494701:FY206_RS13985
uniprot id: A0A5C1C1Y1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
messages: Cell membrane
messages: Membrane

2494701:FY206 RS09600
gene id: 2494701:FY206_RS09600
uniprot id: A0A5C1BYV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CsgC/AgfC family.
messages: Periplasm

2494701:FY206 RS17320
gene id: 2494701:FY206_RS17320
uniprot id: A0A5C1C2E1
names: Function
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.
messages: Functions in two distinct reactions of the de novo folate biosynthetic pathway. Catalyzes the addition of a glutamate residue to dihydropteroate (7,8-dihydropteroate or H2Pte) to form dihydrofolate (7,8-dihydrofolate monoglutamate or H2Pte-Glu). Also catalyzes successive additions of L-glutamate to tetrahydrofolate or 10-formyltetrahydrofolate or 5,10-methylenetetrahydrofolate, leading to folylpolyglutamate derivatives.

2494701:FY206 RS00960
gene id: 2494701:FY206_RS00960
uniprot id: A0A5C1BV97
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

2494701:FY206 RS00100
gene id: 2494701:FY206_RS00100
uniprot id: A0A5C1BU02
names: Subcellular Location Annotation
messages: Membrane

2494701:FY206 RS03090
gene id: 2494701:FY206_RS03090
uniprot id: A0A5C1BV60
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RraB family.
messages: Cytoplasm
messages: Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome.
messages: Interacts with the C-terminal region of Rne.

2494701:FY206 RS02735
gene id: 2494701:FY206_RS02735
uniprot id: A0A5C1BVN8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

2494701:FY206 RS16195
gene id: 2494701:FY206_RS16195
uniprot id: A0A5C1C1Z8
names: Subcellular Location Annotation
messages: Membrane

2494701:FY206 RS04335
gene id: 2494701:FY206_RS04335
uniprot id: A0A5C1BVY5
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
messages: Repressed under conditions of excess protein secretion capacity and derepressed when protein secretion becomes limiting. This is regulated by SecM.

2494701:FY206 RS21105
gene id: 2494701:FY206_RS21105
uniprot id: A0A5C1C5K9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease beta subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

2494701:FY206 RS21425
gene id: 2494701:FY206_RS21425
uniprot id: A0A5C1C4E8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RlmG family.
messages: Cytoplasm
messages: Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA.

2494701:FY206 RS07355
gene id: 2494701:FY206_RS07355
uniprot id: A0A5C1BXN3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. MrdB/RodA subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell wall elongation.

2494701:FY206 RS20275
gene id: 2494701:FY206_RS20275
uniprot id: A0A5C1C572
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA-modifying YgfZ family.
messages: Cytoplasm
messages: Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication.

2494701:FY206 RS06430
gene id: 2494701:FY206_RS06430
uniprot id: A0A5C1BX01
names: Subcellular Location Annotation
messages: Membrane

2494701:FY206 RS22480
gene id: 2494701:FY206_RS22480
uniprot id: A0A5C1C5A7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

2494701:FY206 RS12180
gene id: 2494701:FY206_RS12180
uniprot id: A0A5C1C6G3
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

2494701:FY206 RS22635
gene id: 2494701:FY206_RS22635
uniprot id: A0A5C1C513
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 4 family.

2494701:FY206 RS05990
gene id: 2494701:FY206_RS05990
uniprot id: A0A5C1BWZ0
names: Subcellular Location Annotation
messages: Membrane

2494701:FY206 RS18070
gene id: 2494701:FY206_RS18070
uniprot id: A0A5C1C2Y5
names: Subcellular Location Annotation
messages: Membrane

2494701:FY206 RS02595
gene id: 2494701:FY206_RS02595
uniprot id: A0A5C1BUX8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Monomer.

2494701:FY206 RS00070
gene id: 2494701:FY206_RS00070
uniprot id: A0A5C1BUN9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with aggregated proteins, together with IbpB, to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress. Aggregated proteins bound to the IbpAB complex are more efficiently refolded and reactivated by the ATP-dependent chaperone systems ClpB and DnaK/DnaJ/GrpE. Its activity is ATP-independent.
messages: Belongs to the small heat shock protein (HSP20) family.
messages: Cytoplasm
messages: Monomer. Forms homomultimers of about 100-150 subunits at optimal growth temperatures. Conformation changes to monomers at high temperatures or high ionic concentrations.

2494701:FY206 RS19455
gene id: 2494701:FY206_RS19455
uniprot id: A0A5C1C3J8
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

2494701:FY206 RS10640
gene id: 2494701:FY206_RS10640
uniprot id: A0A5C1C0E4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

2494701:FY206 RS06505
gene id: 2494701:FY206_RS06505
uniprot id: A0A5C1BWW0
names: Subcellular Location Annotation
messages: Cell inner membrane

2494701:FY206 RS01320
gene id: 2494701:FY206_RS01320
uniprot id: A0A5C1BUB8
names: Similarity
messages: Belongs to the aspartokinase family.

2494701:FY206 RS16125
gene id: 2494701:FY206_RS16125
uniprot id: A0A5C1C338
names: Subcellular Location Annotation
messages: Membrane

2494701:FY206 RS07375
gene id: 2494701:FY206_RS07375
uniprot id: A0A5C1BYJ5
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

2494701:FY206 RS10575
gene id: 2494701:FY206_RS10575
uniprot id: A0A5C1BYZ5
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

2494701:FY206 RS16560
gene id: 2494701:FY206_RS16560
uniprot id: A0A5C1C6S6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0387 family.
messages: Cell membrane

2494701:FY206 RS18190
gene id: 2494701:FY206_RS18190
uniprot id: A0A5C1C335
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Membrane

2494701:FY206 RS22370
gene id: 2494701:FY206_RS22370
uniprot id: A0A5C1C548
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

2494701:FY206 RS04420
gene id: 2494701:FY206_RS04420
uniprot id: A0A5C1BVV9
names: Function
names: Subunit
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
messages: Homodimer. Part of the PDH complex, consisting of multiple copies of pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

2494701:FY206 RS01205
gene id: 2494701:FY206_RS01205
uniprot id: A0A5C1BU75
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Nudix hydrolase family. NudC subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Divalent metal cations. Mg(2+) or Mn(2+).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: mRNA decapping enzyme that specifically removes the nicotinamide adenine dinucleotide (NAD) cap from a subset of mRNAs by hydrolyzing the diphosphate linkage to produce nicotinamide mononucleotide (NMN) and 5' monophosphate mRNA. The NAD-cap is present at the 5'-end of some mRNAs and stabilizes RNA against 5'-processing. Has preference for mRNAs with a 5'-end purine. Catalyzes the hydrolysis of a broad range of dinucleotide pyrophosphates.

2494701:FY206 RS20395
gene id: 2494701:FY206_RS20395
uniprot id: A0A5C1C592
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.

2494701:FY206 RS07275
gene id: 2494701:FY206_RS07275
uniprot id: A0A5C1BYF8
names: Similarity
messages: Belongs to the universal stress protein A family.

2494701:FY206 RS12090
gene id: 2494701:FY206_RS12090
uniprot id: A0A5C1C001
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.

2494701:FY206 RS06845
gene id: 2494701:FY206_RS06845
uniprot id: A0A5C1BXE6
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

2494701:FY206 RS21905
gene id: 2494701:FY206_RS21905
uniprot id: A0A5C1C516
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RapZ-like family. RapZ subfamily.
messages: Homotrimer.
messages: Modulates the synthesis of GlmS, by affecting the processing and stability of the regulatory small RNA GlmZ. When glucosamine-6-phosphate (GlcN6P) concentrations are high in the cell, RapZ binds GlmZ and targets it to cleavage by RNase E. Consequently, GlmZ is inactivated and unable to activate GlmS synthesis. Under low GlcN6P concentrations, RapZ is sequestered and inactivated by an other regulatory small RNA, GlmY, preventing GlmZ degradation and leading to synthesis of GlmS.

2494701:FY206 RS01565
gene id: 2494701:FY206_RS01565
uniprot id: A0A5C1BVK7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. Binds to the 16 bp palindromic sequence 5'-CTGTATATATATACAG-3'. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

2494701:FY206 RS06795
gene id: 2494701:FY206_RS06795
uniprot id: A0A5C1BX20
names: Subcellular Location Annotation
messages: Membrane

2494701:FY206 RS04695
gene id: 2494701:FY206_RS04695
uniprot id: A0A5C1BWM2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/UDP phosphorylase family. MtnN subfamily.
messages: Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively. Also cleaves 5'-deoxyadenosine, a toxic by-product of radical S-adenosylmethionine (SAM) enzymes, into 5-deoxyribose and adenine. Thus, is required for in vivo function of the radical SAM enzymes biotin synthase and lipoic acid synthase, that are inhibited by 5'-deoxyadenosine accumulation.
messages: Homodimer.

2494701:FY206 RS10615
gene id: 2494701:FY206_RS10615
uniprot id: A0A5C1BZC2
names: Function
names: Similarity
messages: Belongs to the SELO family.
messages: Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).

2494701:FY206 RS12445
gene id: 2494701:FY206_RS12445
uniprot id: A0A5C1C0A7
names: Similarity
messages: Belongs to the mannitol dehydrogenase family. UxaB subfamily.

2494701:FY206 RS00715
gene id: 2494701:FY206_RS00715
uniprot id: A0A5C1BTZ0
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.

2494701:FY206 RS11225
gene id: 2494701:FY206_RS11225
uniprot id: A0A5C1BZU1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tus family.
messages: Cytoplasm
messages: Trans-acting protein required for termination of DNA replication. Binds to DNA replication terminator sequences (terA to terF) to prevent the passage of replication forks. The termination efficiency will be affected by the affinity of this protein for the terminator sequence.

2494701:FY206 RS04940
gene id: 2494701:FY206_RS04940
uniprot id: A0A5C1BWE9
names: Subcellular Location Annotation
messages: Membrane

2494701:FY206 RS03965
gene id: 2494701:FY206_RS03965
uniprot id: A0A5C1BVL6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 1 subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

2494701:FY206 RS17925
gene id: 2494701:FY206_RS17925
uniprot id: A0A5C1C2N0
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

2494701:FY206 RS08935
gene id: 2494701:FY206_RS08935
uniprot id: A0A5C1BY88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein SsuA/TauA family.
messages: Periplasm

2494701:FY206 RS07690
gene id: 2494701:FY206_RS07690
uniprot id: A0A5C1BXT8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

2494701:FY206 RS05615
gene id: 2494701:FY206_RS05615
uniprot id: A0A5C1BWQ8
names: Similarity
messages: Belongs to the UPF0401 family.

2494701:FY206 RS04590
gene id: 2494701:FY206_RS04590
uniprot id: A0A5C1BWK0
names: Function
names: Similarity
messages: Belongs to the HPPK family.
messages: Catalyzes the transfer of pyrophosphate from adenosine triphosphate (ATP) to 6-hydroxymethyl-7,8-dihydropterin, an enzymatic step in folate biosynthesis pathway.

2494701:FY206 RS04775
gene id: 2494701:FY206_RS04775
uniprot id: A0A5C1BX79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

2494701:FY206 RS16810
gene id: 2494701:FY206_RS16810
uniprot id: A0A5C1C237
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

2494701:FY206 RS22955
gene id: 2494701:FY206_RS22955
uniprot id: A0A5C1C685
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. YhhS family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

2494701:FY206 RS01570
gene id: 2494701:FY206_RS01570
uniprot id: A0A5C1BUQ9
names: Subcellular Location Annotation
messages: Membrane

2494701:FY206 RS21560
gene id: 2494701:FY206_RS21560
uniprot id: A0A5C1C4C6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid/polyamine transporter 2 family. SdaC/TdcC subfamily.
messages: Cell inner membrane
messages: Involved in the import of threonine and serine into the cell, with the concomitant import of a proton (symport system).
messages: Membrane

2494701:FY206 RS02160
gene id: 2494701:FY206_RS02160
uniprot id: A0A5C1BUQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane

2494701:FY206 RS22435
gene id: 2494701:FY206_RS22435
uniprot id: A0A5C1C5X4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

2494701:FY206 RS20755
gene id: 2494701:FY206_RS20755
uniprot id: A0A5C1C4F2
names: Similarity
messages: Belongs to the iron-containing alcohol dehydrogenase family.

2494701:FY206 RS00785
gene id: 2494701:FY206_RS00785
uniprot id: A0A5C1BUE1
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

2494701:FY206 RS04465
gene id: 2494701:FY206_RS04465
uniprot id: A0A5C1BWA5
names: Similarity
messages: Belongs to the glycosyl hydrolase 24 family.

2494701:FY206 RS20605
gene id: 2494701:FY206_RS20605
uniprot id: A0A5C1C3Z4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HpcH/HpaI aldolase family. Citrate lyase beta subunit subfamily.
messages: Cytoplasm
messages: Oligomer with a subunit composition of (alpha,beta,gamma)6.
messages: Represents a citryl-ACP lyase.

2494701:FY206 RS14055
gene id: 2494701:FY206_RS14055
uniprot id: A0A5C1C1K1
names: Function
names: Similarity
messages: Belongs to the gamma-glutamylcyclotransferase family.
messages: Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides.

2494701:FY206 RS02755
gene id: 2494701:FY206_RS02755
uniprot id: A0A5C1BV06
names: Subcellular Location Annotation
messages: Membrane

2494701:FY206 RS15710
gene id: 2494701:FY206_RS15710
uniprot id: A0A5C1C1G6
names: Subcellular Location Annotation
names: Subunit
messages: Cell inner membrane
messages: Homodimer.

2494701:FY206 RS00565
gene id: 2494701:FY206_RS00565
uniprot id: A0A5C1BUM9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nucleoid occlusion factor SlmA family.
messages: Homodimer. Interacts with FtsZ.
messages: Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions.
messages: nucleoid

2494701:FY206 RS02880
gene id: 2494701:FY206_RS02880
uniprot id: A0A5C1BV09
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

2494701:FY206 RS19555
gene id: 2494701:FY206_RS19555
uniprot id: A0A5C1C3Q9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PAPS reductase family. CysD subfamily.
messages: Heterodimer composed of CysD, the smaller subunit, and CysN.
messages: With CysN forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.

2494701:FY206 RS21020
gene id: 2494701:FY206_RS21020
uniprot id: A0A5C1C6V6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the periplasmic pilus chaperone family.
messages: Periplasm

2494701:FY206 RS01485
gene id: 2494701:FY206_RS01485
uniprot id: A0A5C1BUL4
names: Similarity
messages: Belongs to the ABC transporter superfamily.

2494701:FY206 RS05095
gene id: 2494701:FY206_RS05095
uniprot id: A0A5C1BW82
names: Function
names: Similarity
messages: Belongs to the FrsA family.
messages: Catalyzes the hydrolysis of esters.

2494701:FY206 RS07260
gene id: 2494701:FY206_RS07260
uniprot id: A0A5C1BXP1
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

2494701:FY206 RS10160
gene id: 2494701:FY206_RS10160
uniprot id: A0A5C1BZS8
names: Subcellular Location Annotation
messages: Cell inner membrane

2494701:FY206 RS07655
gene id: 2494701:FY206_RS07655
uniprot id: A0A5C1BY33
names: Similarity
messages: Belongs to the citrate synthase family.

2494701:FY206 RS20975
gene id: 2494701:FY206_RS20975
uniprot id: A0A5C1C436
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

2494701:FY206 RS07970
gene id: 2494701:FY206_RS07970
uniprot id: A0A5C1BXH4
names: Similarity
names: Subunit
messages: Belongs to the MoaE family.
messages: Heterotetramer of 2 MoaD subunits and 2 MoaE subunits. Also stable as homodimer. The enzyme changes between these two forms during catalysis.

2494701:FY206 RS18500
gene id: 2494701:FY206_RS18500
uniprot id: A0A5C1C2Z9
names: Function
messages: Acts as a radical domain for damaged PFL and possibly other radical proteins.

2494701:FY206 RS08005
gene id: 2494701:FY206_RS08005
uniprot id: A0A5C1BY19
names: Subcellular Location Annotation
messages: Membrane

2494701:FY206 RS13430
gene id: 2494701:FY206_RS13430
uniprot id: A0A5C1C0D0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0283 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

2494701:FY206 RS08610
gene id: 2494701:FY206_RS08610
uniprot id: A0A5C1BY92
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

2494701:FY206 RS22250
gene id: 2494701:FY206_RS22250
uniprot id: A0A5C1C567
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

2494701:FY206 RS11050
gene id: 2494701:FY206_RS11050
uniprot id: A0A5C1BZD4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxine kinase family. PdxY subfamily.
messages: Homodimer.
messages: Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP.

2494701:FY206 RS17105
gene id: 2494701:FY206_RS17105
uniprot id: A0A5C1C3K8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4 family.
messages: Composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: Membrane

2494701:FY206 RS07730
gene id: 2494701:FY206_RS07730
uniprot id: A0A5C1BXL2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbD/TolR family.
messages: Cell inner membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. Required, with TolQ, for the proton motive force-dependent activation of TolA and for TolA-Pal interaction.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

2494701:FY206 RS11215
gene id: 2494701:FY206_RS11215
uniprot id: A0A5C1BZY3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I fumarase family.
messages: Catalyzes the reversible hydration of fumarate to (S)-malate.
messages: Homodimer.

2494701:FY206 RS18300
gene id: 2494701:FY206_RS18300
uniprot id: A0A5C1C2V6
names: Function
names: Similarity
messages: A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters.
messages: Belongs to the NifU family.

2494701:FY206 RS19645
gene id: 2494701:FY206_RS19645
uniprot id: A0A5C1C4U7
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

2494701:FY206 RS00720
gene id: 2494701:FY206_RS00720
uniprot id: A0A5C1BTU3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecB family.
messages: Cytoplasm
messages: Homotetramer, a dimer of dimers. One homotetramer interacts with 1 SecA dimer.
messages: One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.

2494701:FY206 RS12150
gene id: 2494701:FY206_RS12150
uniprot id: A0A5C1BZS1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell inner membrane
messages: Membrane

2494701:FY206 RS06100
gene id: 2494701:FY206_RS06100
uniprot id: A0A5C1BWM6
names: Similarity
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.

2494701:FY206 RS02990
gene id: 2494701:FY206_RS02990
uniprot id: A0A5C1BVA8
names: Function
names: Similarity
messages: Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Belongs to the organic radical-activating enzymes family.

2494701:FY206 RS22375
gene id: 2494701:FY206_RS22375
uniprot id: A0A5C1C4W4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

2494701:FY206 RS17795
gene id: 2494701:FY206_RS17795
uniprot id: A0A5C1C347
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CysZ family.
messages: Cell inner membrane
messages: High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway.

2494701:FY206 RS06185
gene id: 2494701:FY206_RS06185
uniprot id: A0A5C1BX02
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

2494701:FY206 RS02820
gene id: 2494701:FY206_RS02820
uniprot id: A0A5C1BVE5
names: Similarity
messages: Belongs to the sodium:galactoside symporter (TC 2.A.2) family.

2494701:FY206 RS15945
gene id: 2494701:FY206_RS15945
uniprot id: A0A5C1C312
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2494701:FY206 RS17670
gene id: 2494701:FY206_RS17670
uniprot id: A0A5C1C2J2
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) per subunit.

2494701:FY206 RS17915
gene id: 2494701:FY206_RS17915
uniprot id: A0A5C1C3X5
names: Subunit
messages: Homodimer.

2494701:FY206 RS24225
gene id: 2494701:FY206_RS24225
uniprot id: A0A5C1C5X8
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the N-terminal section; belongs to the CdiA toxin family.
messages: target cell cytoplasm

2494701:FY206 RS18920
gene id: 2494701:FY206_RS18920
uniprot id: A0A5C1C3N6
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

2494701:FY206 RS17135
gene id: 2494701:FY206_RS17135
uniprot id: A0A5C1C297
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the complex I 75 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Composed of 13 different subunits. Subunits NuoCD, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

2494701:FY206 RS10170
gene id: 2494701:FY206_RS10170
uniprot id: A0A5C1C067
names: Function
names: Similarity
names: Subunit
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
messages: Catalyzes two reactions in de novo purine nucleotide biosynthesis. Catalyzes the breakdown of 5-aminoimidazole- (N-succinylocarboxamide) ribotide (SAICAR or 2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate) to 5-aminoimidazole-4-carboxamide ribotide (AICAR or 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide) and fumarate, and of adenylosuccinate (ADS or N(6)-(1,2-dicarboxyethyl)-AMP) to adenosine monophosphate (AMP) and fumarate.
messages: Homotetramer. Residues from neighboring subunits contribute catalytic and substrate-binding residues to each active site.

2494701:FY206 RS09055
gene id: 2494701:FY206_RS09055
uniprot id: A0A5C1BZB2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HspQ family.
messages: Cytoplasm
messages: Involved in the degradation of certain denaturated proteins, including DnaA, during heat shock stress.

2494701:FY206 RS11150
gene id: 2494701:FY206_RS11150
uniprot id: A0A5C1BZF0
names: Subcellular Location Annotation
messages: Membrane

2494701:FY206 RS01995
gene id: 2494701:FY206_RS01995
uniprot id: A0A5C1C6D9
names: Similarity
messages: Belongs to the antirestriction protein family.

2494701:FY206 RS21055
gene id: 2494701:FY206_RS21055
uniprot id: A0A5C1C7K8
names: Subcellular Location Annotation
messages: Membrane

2494701:FY206 RS03540
gene id: 2494701:FY206_RS03540
uniprot id: A0A5C1BVD1
names: Subcellular Location Annotation
messages: Membrane

2494701:FY206 RS10715
gene id: 2494701:FY206_RS10715
uniprot id: A0A5C1BZB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the periplasmic pilus chaperone family.
messages: Periplasm

2494701:FY206 RS21450
gene id: 2494701:FY206_RS21450
uniprot id: A0A5C1C4A7
names: Similarity
messages: Belongs to the UxaA family.

2494701:FY206 RS12615
gene id: 2494701:FY206_RS12615
uniprot id: A0A5C1C0D5
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

2494701:FY206 RS14425
gene id: 2494701:FY206_RS14425
uniprot id: A0A5C1C1B6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

2494701:FY206 RS06310
gene id: 2494701:FY206_RS06310
uniprot id: A0A5C1BXY5
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

2494701:FY206 RS09500
gene id: 2494701:FY206_RS09500
uniprot id: A0A5C1BZH1
names: Similarity
messages: Belongs to the arylamine N-acetyltransferase family.

2494701:FY206 RS03085
gene id: 2494701:FY206_RS03085
uniprot id: A0A5C1BVI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

2494701:FY206 RS06610
gene id: 2494701:FY206_RS06610
uniprot id: A0A5C1BWX1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

2494701:FY206 RS17325
gene id: 2494701:FY206_RS17325
uniprot id: A0A5C1C2E0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

2494701:FY206 RS10960
gene id: 2494701:FY206_RS10960
uniprot id: A0A5C1BZL9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase T family.
messages: Binds two Mg(2+) per subunit. The active form of the enzyme binds two Mg(2+) ions in its active site. The first Mg(2+) forms only one salt bridge with the protein.
messages: Homodimer.
messages: Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis.

2494701:FY206 RS09855
gene id: 2494701:FY206_RS09855
uniprot id: A0A5C1BZB7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgI family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

2494701:FY206 RS18245
gene id: 2494701:FY206_RS18245
uniprot id: A0A5C1C2U1
names: Subcellular Location Annotation
messages: Membrane

2494701:FY206 RS01870
gene id: 2494701:FY206_RS01870
uniprot id: A0A5C1BUY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2494701:FY206 RS11885
gene id: 2494701:FY206_RS11885
uniprot id: A0A5C1BZL8
names: Similarity
messages: Belongs to the CFA/CMAS family.

2494701:FY206 RS09590
gene id: 2494701:FY206_RS09590
uniprot id: A0A5C1BYR4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CsgA/CsgB family.
messages: Fimbrium

2494701:FY206 RS04325
gene id: 2494701:FY206_RS04325
uniprot id: A0A5C1BW35
names: Function
names: Similarity
messages: Belongs to the LpxC family.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.

2494701:FY206 RS24560
gene id: 2494701:FY206_RS24560
uniprot id: A0A5C1C7E0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fimbrial export usher family.
messages: Cell outer membrane
messages: Membrane

2494701:FY206 RS23000
gene id: 2494701:FY206_RS23000
uniprot id: A0A5C1C5G4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DegT/DnrJ/EryC1 family. ArnB subfamily.
messages: Catalyzes the conversion of UDP-4-keto-arabinose (UDP-Ara4O) to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.
messages: Homodimer.

2494701:FY206 RS19960
gene id: 2494701:FY206_RS19960
uniprot id: A0A5C1C3W3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2494701:FY206 RS21045
gene id: 2494701:FY206_RS21045
uniprot id: A0A5C1C5U3
names: Function
names: Similarity
messages: Belongs to the GlnE family.
messages: Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell.

2494701:FY206 RS22455
gene id: 2494701:FY206_RS22455
uniprot id: A0A5C1C6H1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

2494701:FY206 RS09945
gene id: 2494701:FY206_RS09945
uniprot id: A0A5C1BYP6
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

2494701:FY206 RS14960
gene id: 2494701:FY206_RS14960
uniprot id: A0A5C1C1M9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

2494701:FY206 RS12125
gene id: 2494701:FY206_RS12125
uniprot id: A0A5C1BZX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

2494701:FY206 RS12955
gene id: 2494701:FY206_RS12955
uniprot id: A0A5C1C078
names: Similarity
messages: Belongs to the Gfa family.

2494701:FY206 RS22095
gene id: 2494701:FY206_RS22095
uniprot id: A0A5C1C519
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2494701:FY206 RS10270
gene id: 2494701:FY206_RS10270
uniprot id: A0A5C1BZU6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0756 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2494701:FY206 RS22450
gene id: 2494701:FY206_RS22450
uniprot id: A0A5C1C4T8
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

2494701:FY206 RS23580
gene id: 2494701:FY206_RS23580
uniprot id: A0A5C1C5U0
names: Function
names: Similarity
messages: Belongs to the frataxin family.
messages: Involved in iron-sulfur (Fe-S) cluster assembly. May act as a regulator of Fe-S biogenesis.

2494701:FY206 RS23995
gene id: 2494701:FY206_RS23995
uniprot id: A0A5C1C602
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ZapB family.
messages: Cytoplasm
messages: Homodimer. The ends of the coiled-coil dimer bind to each other, forming polymers. Interacts with FtsZ.
messages: Non-essential, abundant cell division factor that is required for proper Z-ring formation. It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle. Its recruitment to the Z-ring requires functional FtsA or ZipA.

2494701:FY206 RS10105
gene id: 2494701:FY206_RS10105
uniprot id: A0A5C1BYS0
names: Function
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family. NagK subfamily.
messages: Catalyzes the phosphorylation of N-acetyl-D-glucosamine (GlcNAc) derived from cell-wall degradation, yielding GlcNAc-6-P.

2494701:FY206 RS21645
gene id: 2494701:FY206_RS21645
uniprot id: A0A5C1C4I2
names: Similarity
messages: Belongs to the UPF0213 family.

2494701:FY206 RS19140
gene id: 2494701:FY206_RS19140
uniprot id: A0A5C1C3F4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

2494701:FY206 RS11430
gene id: 2494701:FY206_RS11430
uniprot id: A0A5C1BZX8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2494701:FY206 RS18605
gene id: 2494701:FY206_RS18605
uniprot id: A0A5C1C320
names: Subcellular Location Annotation
messages: Cytoplasm

2494701:FY206 RS10190
gene id: 2494701:FY206_RS10190
uniprot id: A0A5C1BZH4
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

2494701:FY206 RS02575
gene id: 2494701:FY206_RS02575
uniprot id: A0A5C1BUV3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2494701:FY206 RS20885
gene id: 2494701:FY206_RS20885
uniprot id: A0A5C1C5H0
names: Domain
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

2494701:FY206 RS02600
gene id: 2494701:FY206_RS02600
uniprot id: A0A5C1BUU9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

2494701:FY206 RS15635
gene id: 2494701:FY206_RS15635
uniprot id: A0A5C1C1X5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliH family.
messages: Cytoplasm
messages: Needed for flagellar regrowth and assembly.

2494701:FY206 RS04015
gene id: 2494701:FY206_RS04015
uniprot id: A0A5C1BVM6
names: Function
names: Similarity
messages: Belongs to the ribF family.
messages: Catalyzes the phosphorylation of riboflavin to FMN followed by the adenylation of FMN to FAD.

2494701:FY206 RS21330
gene id: 2494701:FY206_RS21330
uniprot id: A0A5C1C5E5
names: Similarity
messages: Belongs to the DapA family.

2494701:FY206 RS10800
gene id: 2494701:FY206_RS10800
uniprot id: A0A5C1C022
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SufE family.
messages: Cytoplasm
messages: Homodimer. Interacts with SufS.
messages: Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process.

2494701:FY206 RS22900
gene id: 2494701:FY206_RS22900
uniprot id: A0A5C1C675
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

2494701:FY206 RS20540
gene id: 2494701:FY206_RS20540
uniprot id: A0A5C1C527
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

2494701:FY206 RS10550
gene id: 2494701:FY206_RS10550
uniprot id: A0A5C1BZ82
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.

2494701:FY206 RS02935
gene id: 2494701:FY206_RS02935
uniprot id: A0A5C1BV19
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the cytochrome b562 family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per molecule.
messages: Electron-transport protein of unknown function.

2494701:FY206 RS16790
gene id: 2494701:FY206_RS16790
uniprot id: A0A5C1C2M2
names: Similarity
messages: Belongs to the peptidase C40 family.

2494701:FY206 RS19225
gene id: 2494701:FY206_RS19225
uniprot id: A0A5C1C4N0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NiCoT transporter (TC 2.A.52) family. RcnA subfamily.
messages: Cell membrane
messages: Efflux system for nickel and cobalt.
messages: Membrane

2494701:FY206 RS22890
gene id: 2494701:FY206_RS22890
uniprot id: A0A5C1C550
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GlpE family.
messages: Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide.
messages: Cytoplasm

2494701:FY206 RS24505
gene id: 2494701:FY206_RS24505
uniprot id: A0A5C1C629
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

2494701:FY206 RS19005
gene id: 2494701:FY206_RS19005
uniprot id: A0A5C1C4I8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone-like protein H-NS family.
messages: nucleoid

2494701:FY206 RS13180
gene id: 2494701:FY206_RS13180
uniprot id: A0A5C1C1K9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 5 family.
messages: Periplasm

2494701:FY206 RS03020
gene id: 2494701:FY206_RS03020
uniprot id: A0A5C1BV51
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

2494701:FY206 RS24720
gene id: 2494701:FY206_RS24720
uniprot id: A0A5C1C6S8
names: Similarity
messages: Belongs to the class-A beta-lactamase family.

2494701:FY206 RS09435
gene id: 2494701:FY206_RS09435
uniprot id: A0A5C1BYG5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Catalyzes the sodium-dependent uptake of extracellular L-proline.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

2494701:FY206 RS14980
gene id: 2494701:FY206_RS14980
uniprot id: A0A5C1C1H1
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

2494701:FY206 RS02615
gene id: 2494701:FY206_RS02615
uniprot id: A0A5C1BVA6
names: Function
names: Similarity
messages: Belongs to the band 7/mec-2 family. HflC subfamily.
messages: HflC and HflK could regulate a protease.

2494701:FY206 RS24305
gene id: 2494701:FY206_RS24305
uniprot id: A0A5C1C5T6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:galactoside symporter (TC 2.A.2) family.
messages: Membrane

2494701:FY206 RS01400
gene id: 2494701:FY206_RS01400
uniprot id: A0A5C1BU92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM86 family.
messages: Membrane

2494701:FY206 RS11590
gene id: 2494701:FY206_RS11590
uniprot id: A0A5C1BZR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0257 family.
messages: Cell membrane

2494701:FY206 RS17120
gene id: 2494701:FY206_RS17120
uniprot id: A0A5C1C298
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: Composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

2494701:FY206 RS10810
gene id: 2494701:FY206_RS10810
uniprot id: A0A5C1BZ52
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A highly abundant outer membrane lipoprotein that controls the distance between the inner and outer membranes. The only protein known to be covalently linked to the peptidoglycan network (PGN). Also non-covalently binds the PGN. The link between the cell outer membrane and PGN contributes to maintenance of the structural and functional integrity of the cell envelope, and maintains the correct distance between the PGN and the outer membrane.
messages: Belongs to the Lpp family.
messages: Cell outer membrane
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: cell wall

2494701:FY206 RS12370
gene id: 2494701:FY206_RS12370
uniprot id: A0A5C1BZV4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

2494701:FY206 RS16345
gene id: 2494701:FY206_RS16345
uniprot id: A0A5C1C1U3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
messages: Cell inner membrane
messages: Part of a tripartite efflux system composed of MdtA, MdtB and MdtC.

2494701:FY206 RS16670
gene id: 2494701:FY206_RS16670
uniprot id: A0A5C1C3C8
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

2494701:FY206 RS06660
gene id: 2494701:FY206_RS06660
uniprot id: A0A5C1BWX9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

2494701:FY206 RS23310
gene id: 2494701:FY206_RS23310
uniprot id: A0A5C1C6W6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AcsB/BcsB family.
messages: Binds the cellulose synthase activator, bis-(3'-5') cyclic diguanylic acid (c-di-GMP).
messages: Cell inner membrane
messages: Tightly associated with the cellulose synthase catalytic subunit.

2494701:FY206 RS13455
gene id: 2494701:FY206_RS13455
uniprot id: A0A5C1C0T5
names: Cofactor
messages: Binds 2 magnesium ions per subunit.

2494701:FY206 RS02610
gene id: 2494701:FY206_RS02610
uniprot id: A0A5C1BW29
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the band 7/mec-2 family. HflK subfamily.
messages: HflC and HflK could encode or regulate a protease.
messages: HflC and HflK may interact to form a multimeric complex.
messages: Membrane

2494701:FY206 RS23315
gene id: 2494701:FY206_RS23315
uniprot id: A0A5C1C6Y6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family.
messages: Catalytic subunit of cellulose synthase. It polymerizes uridine 5'-diphosphate glucose to cellulose.
messages: Cell inner membrane

2494701:FY206 RS22380
gene id: 2494701:FY206_RS22380
uniprot id: A0A5C1C587
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

2494701:FY206 RS19580
gene id: 2494701:FY206_RS19580
uniprot id: A0A5C1C3H7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Alpha(8)-beta(8). The alpha component is a flavoprotein, the beta component is a hemoprotein.
messages: Belongs to the NADPH-dependent sulphite reductase flavoprotein subunit CysJ family.
messages: Binds 1 FAD per subunit.
messages: Binds 1 FMN per subunit.
messages: Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component.
messages: In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
messages: In the N-terminal section; belongs to the flavodoxin family.

2494701:FY206 RS22910
gene id: 2494701:FY206_RS22910
uniprot id: A0A5C1C5F5
names: Activity Regulation
names: Function
names: Similarity
names: Subunit
messages: Allosterically activated by fructose-1,6-bisphosphate (F16BP) and inhibited by AMP.
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
messages: Homotetramer.
messages: Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.

2494701:FY206 RS17100
gene id: 2494701:FY206_RS17100
uniprot id: A0A5C1C2T3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

2494701:FY206 RS01545
gene id: 2494701:FY206_RS01545
uniprot id: A0A5C1BUT1
names: Similarity
messages: Belongs to the gluconokinase GntK/GntV family.

2494701:FY206 RS21095
gene id: 2494701:FY206_RS21095
uniprot id: A0A5C1C451
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UreD family.
messages: Cytoplasm
messages: Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
messages: UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

2494701:FY206 RS21780
gene id: 2494701:FY206_RS21780
uniprot id: A0A5C1C4V9
names: Similarity
messages: Belongs to the peptidase S13 family.

2494701:FY206 RS04885
gene id: 2494701:FY206_RS04885
uniprot id: A0A5C1BWI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2494701:FY206 RS14100
gene id: 2494701:FY206_RS14100
uniprot id: A0A5C1C128
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LolB family.
messages: Cell outer membrane
messages: Membrane
messages: Monomer.
messages: Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein.

2494701:FY206 RS14670
gene id: 2494701:FY206_RS14670
uniprot id: A0A5C1C101
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Catalyzes the dehydration of 6-phospho-D-gluconate to 2-dehydro-3-deoxy-6-phospho-D-gluconate.

2494701:FY206 RS07780
gene id: 2494701:FY206_RS07780
uniprot id: A0A5C1BXH3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

2494701:FY206 RS24640
gene id: 2494701:FY206_RS24640
uniprot id: A0A5C1C6F0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

2494701:FY206 RS11090
gene id: 2494701:FY206_RS11090
uniprot id: A0A5C1C0M5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.
messages: Binds 3 [4Fe-4S] clusters.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

2494701:FY206 RS18280
gene id: 2494701:FY206_RS18280
uniprot id: A0A5C1C3C1
names: Similarity
messages: Belongs to the adrenodoxin/putidaredoxin family.

2494701:FY206 RS04625
gene id: 2494701:FY206_RS04625
uniprot id: A0A5C1BW03
names: Function
names: Similarity
messages: Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.

2494701:FY206 RS19915
gene id: 2494701:FY206_RS19915
uniprot id: A0A5C1C3N5
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

2494701:FY206 RS07630
gene id: 2494701:FY206_RS07630
uniprot id: A0A5C1BYM1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.
messages: Provides significant protection from radiation damage and may be involved in the degradation of radiation-damaged nucleotides.
messages: Toroid-shaped homohexamer. In the hexamer, 3 dimers assemble to form a ring-like structure surrounding a central hole.

2494701:FY206 RS02515
gene id: 2494701:FY206_RS02515
uniprot id: A0A5C1BV20
names: Cofactor
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.

2494701:FY206 RS08015
gene id: 2494701:FY206_RS08015
uniprot id: A0A5C1BXR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0194 family.
messages: Periplasm

2494701:FY206 RS16590
gene id: 2494701:FY206_RS16590
uniprot id: A0A5C1C3B3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinone-dependent D-lactate dehydrogenase family.
messages: Catalyzes the oxidation of D-lactate to pyruvate.
messages: Cell inner membrane

2494701:FY206 RS23490
gene id: 2494701:FY206_RS23490
uniprot id: A0A5C1C5E8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LysR transcriptional regulatory family.
messages: Cytoplasm

2494701:FY206 RS17180
gene id: 2494701:FY206_RS17180
uniprot id: A0A5C1C3M1
names: Subcellular Location Annotation
messages: Membrane

2494701:FY206 RS00580
gene id: 2494701:FY206_RS00580
uniprot id: A0A5C1BU93
names: Similarity
messages: Belongs to the UPF0758 family. YicR subfamily.

2494701:FY206 RS16575
gene id: 2494701:FY206_RS16575
uniprot id: A0A5C1C2C8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2494701:FY206 RS17350
gene id: 2494701:FY206_RS17350
uniprot id: A0A5C1C2L1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a regulator of flagellar gene expression by modulating the protein level of the anti sigma factor FlgM upon sensing ring completion or hook elongation. Flk could inhibit FlgM secretion by acting as a braking system for the flagellar-associated type III secretion system.
messages: Belongs to the flk family.
messages: Cell inner membrane

2494701:FY206 RS05950
gene id: 2494701:FY206_RS05950
uniprot id: A0A5C1BWJ8
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

2494701:FY206 RS14815
gene id: 2494701:FY206_RS14815
uniprot id: A0A5C1C2F7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CheZ family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P).

2494701:FY206 RS18355
gene id: 2494701:FY206_RS18355
uniprot id: A0A5C1C4L7
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
messages: Belongs to the globin family. Two-domain flavohemoproteins subfamily.
messages: Binds 1 FAD per subunit.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Consists of two distinct domains; an N-terminal heme-containing oxygen-binding domain and a C-terminal reductase domain with binding sites for FAD and NAD(P)H.
messages: In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
messages: Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2494701:FY206 RS24360
gene id: 2494701:FY206_RS24360
uniprot id: A0A5C1C699
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
messages: Single-chain monomer with multiple functions.

2494701:FY206 RS02465
gene id: 2494701:FY206_RS02465
uniprot id: A0A5C1BUV9
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome. Modification of Lys-34 is required for alleviation.
messages: May be beta-lysylated on the epsilon-amino group of Lys-34 by the combined action of EpmA and EpmB, and then hydroxylated on the C5 position of the same residue by EpmC (if this protein is present). Lysylation is critical for the stimulatory effect of EF-P on peptide-bond formation. The lysylation moiety may extend toward the peptidyltransferase center and stabilize the terminal 3-CCA end of the tRNA. Hydroxylation of the C5 position on Lys-34 may allow additional potential stabilizing hydrogen-bond interactions with the P-tRNA.

2494701:FY206 RS22535
gene id: 2494701:FY206_RS22535
uniprot id: A0A5C1C609
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DsrH/TusB family.
messages: Cytoplasm
messages: Heterohexamer, formed by a dimer of trimers. The hexameric TusBCD complex contains 2 copies each of TusB, TusC and TusD. The TusBCD complex interacts with TusE.
messages: Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions.

2494701:FY206 RS13600
gene id: 2494701:FY206_RS13600
uniprot id: A0A5C1C127
names: Similarity
messages: Belongs to the UPF0509 family.

2494701:FY206 RS16330
gene id: 2494701:FY206_RS16330
uniprot id: A0A5C1C1T8
names: Subcellular Location Annotation
messages: Membrane

2494701:FY206 RS01560
gene id: 2494701:FY206_RS01560
uniprot id: A0A5C1BUG5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of sn-l,2-diacylglycerol (DAG) to phosphatidic acid. Involved in the recycling of diacylglycerol produced as a by-product during membrane-derived oligosaccharide (MDO) biosynthesis.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

2494701:FY206 RS06325
gene id: 2494701:FY206_RS06325
uniprot id: A0A5C1BWY3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).

2494701:FY206 RS03730
gene id: 2494701:FY206_RS03730
uniprot id: A0A5C1BW41
names: Function
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is unknown.

2494701:FY206 RS07840
gene id: 2494701:FY206_RS07840
uniprot id: A0A5C1BXT2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: AcrA-AcrB-AcrZ-TolC is a drug efflux protein complex with a broad substrate specificity. This protein binds to AcrB and is required for efflux of some but not all substrates, suggesting it may influence the specificity of drug export.
messages: Belongs to the AcrZ family.
messages: Cell membrane
messages: Part of the AcrA-AcrB-AcrZ-TolC efflux pump, interacts directly with AcrB.

2494701:FY206 RS06250
gene id: 2494701:FY206_RS06250
uniprot id: A0A5C1BWQ4
names: Subcellular Location Annotation
messages: Membrane

2494701:FY206 RS20495
gene id: 2494701:FY206_RS20495
uniprot id: A0A5C1C3X9
names: Similarity
messages: Belongs to the EndA/NucM nuclease family.

2494701:FY206 RS23355
gene id: 2494701:FY206_RS23355
uniprot id: A0A5C1C5D0
names: Function
names: Similarity
messages: Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon.
messages: Belongs to the biotin--protein ligase family.

2494701:FY206 RS13795
gene id: 2494701:FY206_RS13795
uniprot id: A0A5C1C1W0
names: Function
names: Similarity
messages: Belongs to the TrpC family.
messages: Belongs to the TrpF family.
messages: Bifunctional enzyme that catalyzes two sequential steps of tryptophan biosynthetic pathway. The first reaction is catalyzed by the isomerase, coded by the TrpF domain; the second reaction is catalyzed by the synthase, coded by the TrpC domain.
messages: In the C-terminal section; belongs to the TrpF family.
messages: In the N-terminal section; belongs to the TrpC family.

2494701:FY206 RS21375
gene id: 2494701:FY206_RS21375
uniprot id: A0A5C1C4S3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LsrG family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the degradation of phospho-AI-2, thereby terminating induction of the lsr operon and closing the AI-2 signaling cycle. Catalyzes the conversion of (4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione (P-DPD) to 3-hydroxy-5-phosphonooxypentane-2,4-dione (P-HPD).

2494701:FY206 RS20385
gene id: 2494701:FY206_RS20385
uniprot id: A0A5C1C3V7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LysE/ArgO transporter (TC 2.A.75) family.
messages: Cell membrane
messages: Involved in the export of arginine. Important to control the intracellular level of arginine and the correct balance between arginine and lysine.
messages: Membrane

2494701:FY206 RS01555
gene id: 2494701:FY206_RS01555
uniprot id: A0A5C1BUC6
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPAT/DAPAT family.
messages: Cell membrane
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

2494701:FY206 RS02915
gene id: 2494701:FY206_RS02915
uniprot id: A0A5C1BV33
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FBPase class 1 family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.

2494701:FY206 RS08595
gene id: 2494701:FY206_RS08595
uniprot id: A0A5C1BYD3
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aquaporins contain two tandem repeats each containing three membrane-spanning domains and a pore-forming loop with the signature motif Asn-Pro-Ala (NPA).
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Cell membrane
messages: Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

2494701:FY206 RS20710
gene id: 2494701:FY206_RS20710
uniprot id: A0A5C1C547
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0114 family.
messages: Cell membrane
messages: Membrane

2494701:FY206 RS02420
gene id: 2494701:FY206_RS02420
uniprot id: A0A5C1BUS4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CutA family.
messages: Binds 1 copper ion per subunit.
messages: Cytoplasm
messages: Homotrimer.
messages: Involved in resistance toward heavy metals.

2494701:FY206 RS07570
gene id: 2494701:FY206_RS07570
uniprot id: A0A5C1BXI4
names: Similarity
messages: Belongs to the phosphohexose mutase family.

2494701:FY206 RS06215
gene id: 2494701:FY206_RS06215
uniprot id: A0A5C1BWR9
names: Similarity
messages: Belongs to the UPF0234 family.

2494701:FY206 RS10910
gene id: 2494701:FY206_RS10910
uniprot id: A0A5C1BZL0
names: Function
messages: Catalyzes the dismutation of two molecules of 6,7-dimethyl-8-ribityllumazine, resulting in the formation of riboflavin and 5-amino-6-(D-ribitylamino)uracil.

2494701:FY206 RS00725
gene id: 2494701:FY206_RS00725
uniprot id: A0A5C1BU57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

2494701:FY206 RS21885
gene id: 2494701:FY206_RS21885
uniprot id: A0A5C1C4I7
names: Function
names: Similarity
messages: Belongs to the ABC transporter superfamily. Outer membrane lipopolysaccharide export (TC 1.B.42) family.
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane. Probably responsible for energy coupling to the transport system.

2494701:FY206 RS10585
gene id: 2494701:FY206_RS10585
uniprot id: A0A5C1BZZ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

2494701:FY206 RS19600
gene id: 2494701:FY206_RS19600
uniprot id: A0A5C1C3P6
names: Subcellular Location Annotation
messages: Membrane

2494701:FY206 RS10520
gene id: 2494701:FY206_RS10520
uniprot id: A0A5C1BYZ6
names: Similarity
messages: Belongs to the fructosamine kinase family.

2494701:FY206 RS11080
gene id: 2494701:FY206_RS11080
uniprot id: A0A5C1BZ75
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

2494701:FY206 RS04710
gene id: 2494701:FY206_RS04710
uniprot id: A0A5C1BW05
names: Similarity
messages: Belongs to the CdaR family.

2494701:FY206 RS23515
gene id: 2494701:FY206_RS23515
uniprot id: A0A5C1C5T3
names: Similarity
messages: Belongs to the Rht family.

2494701:FY206 RS17005
gene id: 2494701:FY206_RS17005
uniprot id: A0A5C1C3J2
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.

2494701:FY206 RS14415
gene id: 2494701:FY206_RS14415
uniprot id: A0A5C1C258
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycosyl hydrolase 37 family.
messages: Monomer.
messages: Periplasm
messages: Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system.

2494701:FY206 RS10350
gene id: 2494701:FY206_RS10350
uniprot id: A0A5C1BZ79
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the type IA topoisomerase family.
messages: Binds two Mg(2+) per subunit.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

2494701:FY206 RS21915
gene id: 2494701:FY206_RS21915
uniprot id: A0A5C1C4N9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 51 family.
messages: Cell inner membrane
messages: Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors.

2494701:FY206 RS11350
gene id: 2494701:FY206_RS11350
uniprot id: A0A5C1BZD8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

2494701:FY206 RS19630
gene id: 2494701:FY206_RS19630
uniprot id: A0A5C1C3I5
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

2494701:FY206 RS16715
gene id: 2494701:FY206_RS16715
uniprot id: A0A5C1C2U2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

2494701:FY206 RS08820
gene id: 2494701:FY206_RS08820
uniprot id: A0A5C1BYI5
names: Subcellular Location Annotation
messages: Membrane

2494701:FY206 RS10995
gene id: 2494701:FY206_RS10995
uniprot id: A0A5C1BZC6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Cu-Zn superoxide dismutase family.
messages: Binds 1 copper ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

2494701:FY206 RS03580
gene id: 2494701:FY206_RS03580
uniprot id: A0A5C1BVT7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Cell inner membrane
messages: Membrane

2494701:FY206 RS22150
gene id: 2494701:FY206_RS22150
uniprot id: A0A5C1C4P1
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the MsrP family.
messages: Binds 1 Mo-molybdopterin (Mo-MPT) cofactor per subunit.
messages: Heterodimer of a catalytic subunit (MsrP) and a heme-binding subunit (MsrQ).
messages: Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide.
messages: Predicted to be exported by the Tat system. The position of the signal peptide cleavage has not been experimentally proven.

2494701:FY206 RS04100
gene id: 2494701:FY206_RS04100
uniprot id: A0A5C1BVW9
names: Domain
names: Function
names: Subcellular Location Annotation
messages: Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation.
messages: Periplasm
messages: The PPIase activity resides only in the second parvulin domain. The N-terminal region and the C-terminal tail are necessary and sufficient for the chaperone activity of SurA. The PPIase activity is dispensable for SurA to function as a chaperone. The N-terminal region and the C-terminal tail are also required for porin recognition.

2494701:FY206 RS20610
gene id: 2494701:FY206_RS20610
uniprot id: A0A5C1C3Y7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CitD family.
messages: Covalent carrier of the coenzyme of citrate lyase.
messages: Cytoplasm
messages: Oligomer with a subunit composition of (alpha,beta,gamma)6.

2494701:FY206 RS23990
gene id: 2494701:FY206_RS23990
uniprot id: A0A5C1C5Z4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RraA family.
messages: Cytoplasm
messages: Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome.
messages: Homotrimer. Binds to both RNA-binding sites in the C-terminal region of Rne and to RhlB.

2494701:FY206 RS08780
gene id: 2494701:FY206_RS08780
uniprot id: A0A5C1BY61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FNT transporter (TC 2.A.44) family.
messages: Membrane

2494701:FY206 RS23765
gene id: 2494701:FY206_RS23765
uniprot id: A0A5C1C5J4
names: Similarity
messages: Belongs to the UPF0438 family.

2494701:FY206 RS07360
gene id: 2494701:FY206_RS07360
uniprot id: A0A5C1BXR4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transpeptidase family. MrdA subfamily.
messages: Catalyzes cross-linking of the peptidoglycan cell wall.
messages: Cell inner membrane

2494701:FY206 RS01070
gene id: 2494701:FY206_RS01070
uniprot id: A0A5C1BVB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

2494701:FY206 RS08740
gene id: 2494701:FY206_RS08740
uniprot id: A0A5C1BZ61
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2494701:FY206 RS13220
gene id: 2494701:FY206_RS13220
uniprot id: A0A5C1C085
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2494701:FY206 RS10785
gene id: 2494701:FY206_RS10785
uniprot id: A0A5C1BZJ2
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

2494701:FY206 RS14885
gene id: 2494701:FY206_RS14885
uniprot id: A0A5C1C1Y9
names: Similarity
messages: Belongs to the MotB family.

2494701:FY206 RS23560
gene id: 2494701:FY206_RS23560
uniprot id: A0A5C1C5T8
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD, in which XerC interacts with XerD via its C-terminal region, XerD interacts with XerC via its C-terminal region and so on.
messages: FtsK may regulate the catalytic switch between XerC and XerD in the heterotetrameric complex during the two steps of the recombination process.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Binds cooperatively to specific DNA consensus sequences that are separated from XerD binding sites by a short central region, forming the heterotetrameric XerC-XerD complex that recombines DNA substrates. The complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. In the complex XerC specifically exchanges the top DNA strands.

2494701:FY206 RS14500
gene id: 2494701:FY206_RS14500
uniprot id: A0A5C1C194
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.
messages: Belongs to the ParA family. MinD subfamily.
messages: Interacts with MinC and FtsZ.
messages: Membrane

2494701:FY206 RS11435
gene id: 2494701:FY206_RS11435
uniprot id: A0A5C1BZF9
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

2494701:FY206 RS08950
gene id: 2494701:FY206_RS08950
uniprot id: A0A5C1BZ94
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

2494701:FY206 RS03400
gene id: 2494701:FY206_RS03400
uniprot id: A0A5C1BVM1
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

2494701:FY206 RS14090
gene id: 2494701:FY206_RS14090
uniprot id: A0A5C1C1A2
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

2494701:FY206 RS00025
gene id: 2494701:FY206_RS00025
uniprot id: A0A5C1BTU5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2494701:FY206 RS04065
gene id: 2494701:FY206_RS04065
uniprot id: A0A5C1BVT4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NAD(P)H dehydrogenase (quinone) family. KefF subfamily.
messages: Cell inner membrane
messages: Homodimer. Interacts with KefC.
messages: Regulatory subunit of a potassium efflux system that confers protection against electrophiles. Required for full activity of KefC. Shows redox enzymatic activity, but this enzymatic activity is not required for activation of KefC.

2494701:FY206 RS14745
gene id: 2494701:FY206_RS14745
uniprot id: A0A5C1C115
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2494701:FY206 RS11665
gene id: 2494701:FY206_RS11665
uniprot id: A0A5C1BZJ4
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

2494701:FY206 RS22465
gene id: 2494701:FY206_RS22465
uniprot id: A0A5C1C599
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

2494701:FY206 RS06440
gene id: 2494701:FY206_RS06440
uniprot id: A0A5C1BXG9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

2494701:FY206 RS23830
gene id: 2494701:FY206_RS23830
uniprot id: A0A5C1C719
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Homodimer.
messages: Represses the transcription of fabB, involved in unsaturated fatty acid (UFA) biosynthesis. By controlling UFA production, FabR directly influences the physical properties of the membrane bilayer.

2494701:FY206 RS24050
gene id: 2494701:FY206_RS24050
uniprot id: A0A5C1C5P3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Cdh family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

2494701:FY206 RS24570
gene id: 2494701:FY206_RS24570
uniprot id: A0A5C1C6A1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PstS family.
messages: Part of the ABC transporter complex PstSACB involved in phosphate import.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

2494701:FY206 RS06980
gene id: 2494701:FY206_RS06980
uniprot id: A0A5C1BXE9
names: Function
names: Similarity
messages: Belongs to the GMC oxidoreductase family.
messages: Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate.

2494701:FY206 RS16035
gene id: 2494701:FY206_RS16035
uniprot id: A0A5C1C299
names: Similarity
messages: Belongs to the UPF0265 family.

2494701:FY206 RS08535
gene id: 2494701:FY206_RS08535
uniprot id: A0A5C1BXT7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A24 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Plays an essential role in type IV pili and type II pseudopili formation by proteolytically removing the leader sequence from substrate proteins and subsequently monomethylating the alpha-amino group of the newly exposed N-terminal phenylalanine.

2494701:FY206 RS06935
gene id: 2494701:FY206_RS06935
uniprot id: A0A5C1BXH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

2494701:FY206 RS06970
gene id: 2494701:FY206_RS06970
uniprot id: A0A5C1BXE4
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

2494701:FY206 RS03865
gene id: 2494701:FY206_RS03865
uniprot id: A0A5C1BVY7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

2494701:FY206 RS18825
gene id: 2494701:FY206_RS18825
uniprot id: A0A5C1C4T4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

2494701:FY206 RS04405
gene id: 2494701:FY206_RS04405
uniprot id: A0A5C1BX10
names: Subcellular Location Annotation
messages: Membrane

2494701:FY206 RS17365
gene id: 2494701:FY206_RS17365
uniprot id: A0A5C1C2P7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Catalyzes the last two steps in the biosynthesis of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the DAO family.
messages: In the N-terminal section; belongs to the methyltransferase superfamily. tRNA (mnm(5)s(2)U34)-methyltransferase family.

2494701:FY206 RS12185
gene id: 2494701:FY206_RS12185
uniprot id: A0A5C1C071
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2494701:FY206 RS04125
gene id: 2494701:FY206_RS04125
uniprot id: A0A5C1BVP4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SNF2/RAD54 helicase family. RapA subfamily.
messages: Interacts with the RNAP. Has a higher affinity for the core RNAP than for the holoenzyme. Its ATPase activity is stimulated by binding to RNAP.
messages: Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair.

2494701:FY206 RS04870
gene id: 2494701:FY206_RS04870
uniprot id: A0A5C1BW32
names: Similarity
messages: Belongs to the tRNA methyltransferase O family.

2494701:FY206 RS24190
gene id: 2494701:FY206_RS24190
uniprot id: A0A5C1C634
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhD family.
messages: Cytoplasm
messages: Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.

2494701:FY206 RS14140
gene id: 2494701:FY206_RS14140
uniprot id: A0A5C1C1B1
names: Similarity
messages: Belongs to the YciI family.

2494701:FY206 RS21115
gene id: 2494701:FY206_RS21115
uniprot id: A0A5C1C6U9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UreE family.
messages: Cytoplasm
messages: Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly.

2494701:FY206 RS04770
gene id: 2494701:FY206_RS04770
uniprot id: A0A5C1BW10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

2494701:FY206 RS21240
gene id: 2494701:FY206_RS21240
uniprot id: A0A5C1C4K6
names: Similarity
messages: Belongs to the colicins ColE2/ColE8/ColE9 and pyocins S1/S2 family.

2494701:FY206 RS15845
gene id: 2494701:FY206_RS15845
uniprot id: A0A5C1C212
names: Similarity
messages: Belongs to the lysine N(6)-hydroxylase/L-ornithine N(5)-oxygenase family.

2494701:FY206 RS12920
gene id: 2494701:FY206_RS12920
uniprot id: A0A5C1C013
names: Subcellular Location Annotation
messages: Membrane

2494701:FY206 RS21950
gene id: 2494701:FY206_RS21950
uniprot id: A0A5C1C688
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

2494701:FY206 RS02105
gene id: 2494701:FY206_RS02105
uniprot id: A0A5C1BUP3
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

2494701:FY206 RS04375
gene id: 2494701:FY206_RS04375
uniprot id: A0A5C1BW19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the N-Me-Phe pilin family.
messages: Membrane

2494701:FY206 RS09865
gene id: 2494701:FY206_RS09865
uniprot id: A0A5C1BZ32
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

2494701:FY206 RS04875
gene id: 2494701:FY206_RS04875
uniprot id: A0A5C1BW27
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RcsF family.
messages: Cell outer membrane
messages: Essential component of the Rcs signaling system, which controls transcription of numerous genes. Plays a role in signal transduction from the cell surface to the histidine kinase RcsC. May detect outer membrane defects.

2494701:FY206 RS12200
gene id: 2494701:FY206_RS12200
uniprot id: A0A5C1C015
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OpgD/OpgG family.
messages: Periplasm
messages: Predicted to be exported by the Tat system. The position of the signal peptide cleavage has not been experimentally proven.
messages: Probably involved in the control of the structural glucose backbone of osmoregulated periplasmic glucans (OPGs).

2494701:FY206 RS07320
gene id: 2494701:FY206_RS07320
uniprot id: A0A5C1BX72
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TatA/E family. TatE subfamily.
messages: Cell inner membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatE shares overlapping functions with TatA.

2494701:FY206 RS22685
gene id: 2494701:FY206_RS22685
uniprot id: A0A5C1C5A6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. TsgA family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

2494701:FY206 RS14105
gene id: 2494701:FY206_RS14105
uniprot id: A0A5C1C0Q3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
messages: Homodimer.

2494701:FY206 RS13045
gene id: 2494701:FY206_RS13045
uniprot id: A0A5C1C0T7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

2494701:FY206 RS01425
gene id: 2494701:FY206_RS01425
uniprot id: A0A5C1BUC2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division. Important for assembly or stability of the septal ring.

2494701:FY206 RS18235
gene id: 2494701:FY206_RS18235
uniprot id: A0A5C1C423
names: Similarity
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.

2494701:FY206 RS00995
gene id: 2494701:FY206_RS00995
uniprot id: A0A5C1BUI6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. GhrB subfamily.
messages: Catalyzes the NADPH-dependent reduction of glyoxylate and hydroxypyruvate into glycolate and glycerate, respectively.
messages: Cytoplasm
messages: Homodimer.

2494701:FY206 RS16695
gene id: 2494701:FY206_RS16695
uniprot id: A0A5C1C3D0
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.
messages: Toroid-shaped homodecamer, composed of two pentamers of five dimers.

2494701:FY206 RS02905
gene id: 2494701:FY206_RS02905
uniprot id: A0A5C1BV64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Cell inner membrane

2494701:FY206 RS22245
gene id: 2494701:FY206_RS22245
uniprot id: A0A5C1C6N7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

2494701:FY206 RS06120
gene id: 2494701:FY206_RS06120
uniprot id: A0A5C1BWR8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YajC family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the SecDF-YidC-YajC translocase complex. The SecDF-YidC-YajC translocase forms a supercomplex with SecYEG, called the holo-translocon (HTL).
messages: The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions.

2494701:FY206 RS09460
gene id: 2494701:FY206_RS09460
uniprot id: A0A5C1BYM2
names: Function
names: Similarity
messages: Belongs to the EfeM/EfeO family.
messages: Involved in Fe(2+) uptake. Could be an iron-binding and/or electron-transfer component.

2494701:FY206 RS09110
gene id: 2494701:FY206_RS09110
uniprot id: A0A5C1BYL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

2494701:FY206 RS04270
gene id: 2494701:FY206_RS04270
uniprot id: A0A5C1BWE3
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2494701:FY206 RS03565
gene id: 2494701:FY206_RS03565
uniprot id: A0A5C1BVF3
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

2494701:FY206 RS16140
gene id: 2494701:FY206_RS16140
uniprot id: A0A5C1C1Y7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

2494701:FY206 RS15640
gene id: 2494701:FY206_RS15640
uniprot id: A0A5C1C1L1
names: Subcellular Location Annotation
messages: Cytoplasm

2494701:FY206 RS02930
gene id: 2494701:FY206_RS02930
uniprot id: A0A5C1BV34
names: Function
names: Similarity
messages: Belongs to the peptidase U62 family.
messages: Metalloprotease involved in CcdA degradation. Suppresses the inhibitory activity of the carbon storage regulator (CsrA).

2494701:FY206 RS18665
gene id: 2494701:FY206_RS18665
uniprot id: A0A5C1C387
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

2494701:FY206 RS19305
gene id: 2494701:FY206_RS19305
uniprot id: A0A5C1C3K7
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. HypB/HupM subfamily.

2494701:FY206 RS19725
gene id: 2494701:FY206_RS19725
uniprot id: A0A5C1C408
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0382 family.
messages: Membrane

2494701:FY206 RS23130
gene id: 2494701:FY206_RS23130
uniprot id: A0A5C1C5J8
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Member of a two-component regulatory system.

2494701:FY206 RS16920
gene id: 2494701:FY206_RS16920
uniprot id: A0A5C1C2X7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the protease inhibitor I11 (ecotin) family.
messages: General inhibitor of pancreatic serine proteases: inhibits chymotrypsin, trypsin, elastases, factor X, kallikrein as well as a variety of other proteases.
messages: Homodimer.
messages: Periplasm

2494701:FY206 RS18495
gene id: 2494701:FY206_RS18495
uniprot id: A0A5C1C390
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DEAD box helicase family. SrmB subfamily.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit at low temperature. Exhibits RNA-stimulated ATP hydrolysis and RNA unwinding activity.
messages: Interacts with the 50S ribosomal subunit.

2494701:FY206 RS03310
gene id: 2494701:FY206_RS03310
uniprot id: A0A5C1BVA5
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

2494701:FY206 RS06465
gene id: 2494701:FY206_RS06465
uniprot id: A0A5C1BY13
names: Similarity
messages: Belongs to the Hha/YmoA/Cnu family.

2494701:FY206 RS21580
gene id: 2494701:FY206_RS21580
uniprot id: A0A5C1C4W0
names: Function
names: Similarity
messages: Belongs to the HIBADH-related family. 2-hydroxy-3-oxopropionate reductase subfamily.
messages: Catalyzes the reduction of tatronate semialdehyde to D-glycerate.

2494701:FY206 RS06645
gene id: 2494701:FY206_RS06645
uniprot id: A0A5C1BXB5
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

2494701:FY206 RS04280
gene id: 2494701:FY206_RS04280
uniprot id: A0A5C1BVX3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

2494701:FY206 RS10945
gene id: 2494701:FY206_RS10945
uniprot id: A0A5C1BZG0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.
messages: Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.
messages: Homodimer.

2494701:FY206 RS17850
gene id: 2494701:FY206_RS17850
uniprot id: A0A5C1C356
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic sulfate-binding protein family.
messages: Periplasm

2494701:FY206 RS09040
gene id: 2494701:FY206_RS09040
uniprot id: A0A5C1BYL4
names: Function
names: Similarity
messages: Belongs to the methylglyoxal synthase family.
messages: Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.

2494701:FY206 RS17950
gene id: 2494701:FY206_RS17950
uniprot id: A0A5C1C2P8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0370 family.
messages: Cell membrane

2494701:FY206 RS24500
gene id: 2494701:FY206_RS24500
uniprot id: A0A5C1C5Z5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

2494701:FY206 RS23570
gene id: 2494701:FY206_RS23570
uniprot id: A0A5C1C8H3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.

2494701:FY206 RS20485
gene id: 2494701:FY206_RS20485
uniprot id: A0A5C1C518
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Cell inner membrane
messages: Membrane

2494701:FY206 RS18120
gene id: 2494701:FY206_RS18120
uniprot id: A0A5C1C352
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

2494701:FY206 RS07740
gene id: 2494701:FY206_RS07740
uniprot id: A0A5C1C6I0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TolB family.
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. TolB occupies a key intermediary position in the Tol-Pal system because it communicates directly with both membrane-embedded components, Pal in the outer membrane and TolA in the inner membrane.
messages: Periplasm
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

2494701:FY206 RS16635
gene id: 2494701:FY206_RS16635
uniprot id: A0A5C1C2J5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell outer membrane
messages: Membrane

2494701:FY206 RS06540
gene id: 2494701:FY206_RS06540
uniprot id: A0A5C1BXI8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Cytoplasm

2494701:FY206 RS04105
gene id: 2494701:FY206_RS04105
uniprot id: A0A5C1BWB2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptD family.
messages: Cell outer membrane
messages: Component of the lipopolysaccharide transport and assembly complex. Interacts with LptE and LptA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.

2494701:FY206 RS00820
gene id: 2494701:FY206_RS00820
uniprot id: A0A5C1BTW3
names: Similarity
messages: Belongs to the HicA mRNA interferase family.

2494701:FY206 RS08870
gene id: 2494701:FY206_RS08870
uniprot id: A0A5C1BYJ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MukE family.
messages: Interacts, and probably forms a ternary complex, with MukF and MukB. The complex formation is stimulated by calcium or magnesium.
messages: Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF.
messages: nucleoid

2494701:FY206 RS12825
gene id: 2494701:FY206_RS12825
uniprot id: A0A5C1C0D6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2494701:FY206 RS22945
gene id: 2494701:FY206_RS22945
uniprot id: A0A5C1C559
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.
messages: Cell inner membrane
messages: Involved in the import of queuosine (Q) precursors, required for Q precursor salvage.

2494701:FY206 RS18685
gene id: 2494701:FY206_RS18685
uniprot id: A0A5C1C333
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2494701:FY206 RS17595
gene id: 2494701:FY206_RS17595
uniprot id: A0A5C1C322
names: Similarity
messages: Belongs to the VgrG protein family.

2494701:FY206 RS17390
gene id: 2494701:FY206_RS17390
uniprot id: A0A5C1C2F0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

2494701:FY206 RS19835
gene id: 2494701:FY206_RS19835
uniprot id: A0A5C1C3P9
names: Function
names: Similarity
messages: Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
messages: Belongs to the Nudix hydrolase family. RppH subfamily.

2494701:FY206 RS08515
gene id: 2494701:FY206_RS08515
uniprot id: A0A5C1BYJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP J family.
messages: Cell inner membrane
messages: Component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm. Part of the pseudopilus tip complex that is critical for the recognition and binding of secretion substrates.
messages: Membrane

2494701:FY206 RS13120
gene id: 2494701:FY206_RS13120
uniprot id: A0A5C1C155
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

2494701:FY206 RS09280
gene id: 2494701:FY206_RS09280
uniprot id: A0A5C1BY77
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20 family.
messages: Binds 2 Zn(2+) ions per subunit.

2494701:FY206 RS10375
gene id: 2494701:FY206_RS10375
uniprot id: A0A5C1C0A0
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

2494701:FY206 RS20950
gene id: 2494701:FY206_RS20950
uniprot id: A0A5C1C4G1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family. ParE type 1 subfamily.
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

2494701:FY206 RS13460
gene id: 2494701:FY206_RS13460
uniprot id: A0A5C1C0F0
names: Similarity
messages: Belongs to the glycosyl hydrolase 65 family.

2494701:FY206 RS15645
gene id: 2494701:FY206_RS15645
uniprot id: A0A5C1C228
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliJ family.
messages: Cell membrane
messages: Flagellar protein that affects chemotactic events.
messages: Membrane

2494701:FY206 RS16320
gene id: 2494701:FY206_RS16320
uniprot id: A0A5C1C1T4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Catalyzes the deamination of dCTP to dUTP.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2494701:FY206 RS22050
gene id: 2494701:FY206_RS22050
uniprot id: A0A5C1C4M1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LDH/MDH superfamily. MDH type 1 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.
messages: Homodimer.

2494701:FY206 RS14525
gene id: 2494701:FY206_RS14525
uniprot id: A0A5C1C0W5
names: Similarity
messages: Belongs to the KAE1 / TsaD family. TsaB subfamily.

2494701:FY206 RS07420
gene id: 2494701:FY206_RS07420
uniprot id: A0A5C1BXS3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

2494701:FY206 RS24070
gene id: 2494701:FY206_RS24070
uniprot id: A0A5C1C5P4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CpxP/Spy family.
messages: Periplasm

2494701:FY206 RS03295
gene id: 2494701:FY206_RS03295
uniprot id: A0A5C1BVX8
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

2494701:FY206 RS21700
gene id: 2494701:FY206_RS21700
uniprot id: A0A5C1C4J2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

2494701:FY206 RS07345
gene id: 2494701:FY206_RS07345
uniprot id: A0A5C1BXM3
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

2494701:FY206 RS15410
gene id: 2494701:FY206_RS15410
uniprot id: A0A5C1C1Z4
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

2494701:FY206 RS00080
gene id: 2494701:FY206_RS00080
uniprot id: A0A5C1BTK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAE transporter (TC 2.A.81) family. YidE subfamily.
messages: Cell membrane

2494701:FY206 RS18435
gene id: 2494701:FY206_RS18435
uniprot id: A0A5C1C454
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

2494701:FY206 RS13485
gene id: 2494701:FY206_RS13485
uniprot id: A0A5C1C0S6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2494701:FY206 RS06790
gene id: 2494701:FY206_RS06790
uniprot id: A0A5C1BXD7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

2494701:FY206 RS20500
gene id: 2494701:FY206_RS20500
uniprot id: A0A5C1C6N3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

2494701:FY206 RS14430
gene id: 2494701:FY206_RS14430
uniprot id: A0A5C1C145
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)-dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility.
messages: Bacterial flagellum basal body
messages: Belongs to the YcgR family.
messages: Monomer. Interacts with the flagellar basal bodies.

2494701:FY206 RS18940
gene id: 2494701:FY206_RS18940
uniprot id: A0A5C1C366
names: Subcellular Location Annotation
messages: Membrane

2494701:FY206 RS13630
gene id: 2494701:FY206_RS13630
uniprot id: A0A5C1C1T1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LapA family.
messages: Cell inner membrane
messages: Involved in the assembly of lipopolysaccharide (LPS).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2494701:FY206 RS19775
gene id: 2494701:FY206_RS19775
uniprot id: A0A5C1C3U5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetyltransferase family. ArgA subfamily.
messages: Cytoplasm
messages: Homohexamer.

2494701:FY206 RS03795
gene id: 2494701:FY206_RS03795
uniprot id: A0A5C1BVN2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/UDP phosphorylase family.
messages: Catalyzes the reversible phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
messages: Homohexamer; trimer of homodimers.

2494701:FY206 RS13350
gene id: 2494701:FY206_RS13350
uniprot id: A0A5C1C0C9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. DbpA subfamily.
messages: Contains an N-terminal domain that binds non-specifically to RNA and a C-terminal domain that binds specifically and tightly to hairpin 92 of 23S rRNA.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes.

2494701:FY206 RS03690
gene id: 2494701:FY206_RS03690
uniprot id: A0A5C1BWL4
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane.

2494701:FY206 RS15600
gene id: 2494701:FY206_RS15600
uniprot id: A0A5C1C1Q9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliS family.
messages: cytosol

2494701:FY206 RS14070
gene id: 2494701:FY206_RS14070
uniprot id: A0A5C1C0P1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

2494701:FY206 RS10650
gene id: 2494701:FY206_RS10650
uniprot id: A0A5C1BZ72
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

2494701:FY206 RS12970
gene id: 2494701:FY206_RS12970
uniprot id: A0A5C1C792
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

2494701:FY206 RS04425
gene id: 2494701:FY206_RS04425
uniprot id: A0A5C1BW28
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 3 lipoyl cofactors covalently.
messages: Forms a 24-polypeptide structural core with octahedral symmetry.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

2494701:FY206 RS21880
gene id: 2494701:FY206_RS21880
uniprot id: A0A5C1C4Y1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptA family.
messages: Component of the lipopolysaccharide transport and assembly complex.
messages: Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm.
messages: Periplasm

2494701:FY206 RS06685
gene id: 2494701:FY206_RS06685
uniprot id: A0A5C1BXA0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2494701:FY206 RS14890
gene id: 2494701:FY206_RS14890
uniprot id: A0A5C1C2F6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Membrane

2494701:FY206 RS13215
gene id: 2494701:FY206_RS13215
uniprot id: A0A5C1C0Q2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2494701:FY206 RS09840
gene id: 2494701:FY206_RS09840
uniprot id: A0A5C1BYM4
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

2494701:FY206 RS13535
gene id: 2494701:FY206_RS13535
uniprot id: A0A5C1C0U2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

2494701:FY206 RS01290
gene id: 2494701:FY206_RS01290
uniprot id: A0A5C1BUN8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

2494701:FY206 RS08965
gene id: 2494701:FY206_RS08965
uniprot id: A0A5C1BYD7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RlmKL family.
messages: Cytoplasm
messages: Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA.

2494701:FY206 RS16745
gene id: 2494701:FY206_RS16745
uniprot id: A0A5C1C3F7
names: Function
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.
messages: Catalyzes the ATP-dependent phosphorylation of fructose-l-phosphate to fructose-l,6-bisphosphate.

2494701:FY206 RS11070
gene id: 2494701:FY206_RS11070
uniprot id: A0A5C1BZN7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

2494701:FY206 RS12015
gene id: 2494701:FY206_RS12015
uniprot id: A0A5C1C014
names: Subcellular Location Annotation
messages: Membrane

2494701:FY206 RS13370
gene id: 2494701:FY206_RS13370
uniprot id: A0A5C1C0C0
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

2494701:FY206 RS04820
gene id: 2494701:FY206_RS04820
uniprot id: A0A5C1BW18
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

2494701:FY206 RS06225
gene id: 2494701:FY206_RS06225
uniprot id: A0A5C1BX06
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
messages: Membrane

2494701:FY206 RS22490
gene id: 2494701:FY206_RS22490
uniprot id: A0A5C1C575
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: Methylated by PrmB.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

2494701:FY206 RS03030
gene id: 2494701:FY206_RS03030
uniprot id: A0A5C1BVI0
names: Similarity
names: Subunit
messages: Belongs to the RutC family.
messages: Homotrimer.

2494701:FY206 RS17750
gene id: 2494701:FY206_RS17750
uniprot id: A0A5C1C3V2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2494701:FY206 RS01695
gene id: 2494701:FY206_RS01695
uniprot id: A0A5C1BUQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Cell inner membrane
messages: Membrane
messages: Transports acetate.

2494701:FY206 RS14225
gene id: 2494701:FY206_RS14225
uniprot id: A0A5C1C1C0
names: Similarity
messages: Belongs to the VgrG protein family.

2494701:FY206 RS07850
gene id: 2494701:FY206_RS07850
uniprot id: A0A5C1BY60
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

2494701:FY206 RS21150
gene id: 2494701:FY206_RS21150
uniprot id: A0A5C1C461
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

2494701:FY206 RS15965
gene id: 2494701:FY206_RS15965
uniprot id: A0A5C1C1V9
names: Similarity
messages: Belongs to the universal stress protein A family.

2494701:FY206 RS16605
gene id: 2494701:FY206_RS16605
uniprot id: A0A5C1C200
names: Subcellular Location Annotation
messages: Membrane

2494701:FY206 RS06275
gene id: 2494701:FY206_RS06275
uniprot id: A0A5C1BX16
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

2494701:FY206 RS07460
gene id: 2494701:FY206_RS07460
uniprot id: A0A5C1BXP3
names: Similarity
messages: Belongs to the UbiH/COQ6 family.

2494701:FY206 RS07610
gene id: 2494701:FY206_RS07610
uniprot id: A0A5C1BXU9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpA family.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds the extracellular potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

2494701:FY206 RS18575
gene id: 2494701:FY206_RS18575
uniprot id: A0A5C1C398
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

2494701:FY206 RS08690
gene id: 2494701:FY206_RS08690
uniprot id: A0A5C1BZ53
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

2494701:FY206 RS21890
gene id: 2494701:FY206_RS21890
uniprot id: A0A5C1C4I6
names: Function
names: Similarity
messages: Belongs to the sigma-54 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

2494701:FY206 RS18170
gene id: 2494701:FY206_RS18170
uniprot id: A0A5C1C371
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M4 family.
messages: Extracellular zinc metalloprotease.
messages: Secreted

2494701:FY206 RS00590
gene id: 2494701:FY206_RS00590
uniprot id: A0A5C1BTS3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

2494701:FY206 RS21865
gene id: 2494701:FY206_RS21865
uniprot id: A0A5C1C4M7
names: Similarity
names: Subunit
messages: Belongs to the SIS family. GutQ/KpsF subfamily.
messages: Homotetramer.

2494701:FY206 RS01260
gene id: 2494701:FY206_RS01260
uniprot id: A0A5C1BVE8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MetA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine.

2494701:FY206 RS23390
gene id: 2494701:FY206_RS23390
uniprot id: A0A5C1C6X2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HemG family.
messages: Belongs to the flavodoxin family.
messages: Binds 1 FMN non-covalently per subunit.
messages: Catalyzes the 6-electron oxidation of protoporphyrinogen IX to form protoporphyrin IX; under anaerobic conditions uses menaquinone as an electron acceptor, under aerobic conditions uses ubiquinone as an electron acceptor.
messages: Cell membrane

2494701:FY206 RS13405
gene id: 2494701:FY206_RS13405
uniprot id: A0A5C1C0E1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase M14 family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in muropeptide degradation. Catalyzes the hydrolysis of the gamma-D-glutamyl-diaminopimelic acid (gamma-D-Glu-Dap) amide bond in the murein tripeptide L-alanyl-gamma-D-glutamyl-meso-diaminopimelic acid, leading to the formation of L-Ala-gamma-D-Glu and Dap.

2494701:FY206 RS08130
gene id: 2494701:FY206_RS08130
uniprot id: A0A5C1BYV4
names: Subcellular Location Annotation
messages: Membrane

2494701:FY206 RS16990
gene id: 2494701:FY206_RS16990
uniprot id: A0A5C1C2K3
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

2494701:FY206 RS06515
gene id: 2494701:FY206_RS06515
uniprot id: A0A5C1BY23
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

2494701:FY206 RS05205
gene id: 2494701:FY206_RS05205
uniprot id: A0A5C1BXF0
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.

2494701:FY206 RS22605
gene id: 2494701:FY206_RS22605
uniprot id: A0A5C1C4X0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

2494701:FY206 RS10345
gene id: 2494701:FY206_RS10345
uniprot id: A0A5C1BZJ8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the selenophosphate synthase 1 family. Class I subfamily.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Homodimer.
messages: Synthesizes selenophosphate from selenide and ATP.

2494701:FY206 RS16655
gene id: 2494701:FY206_RS16655
uniprot id: A0A5C1C208
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion.
messages: Homodimer.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

2494701:FY206 RS21030
gene id: 2494701:FY206_RS21030
uniprot id: A0A5C1C4G0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.

2494701:FY206 RS13930
gene id: 2494701:FY206_RS13930
uniprot id: A0A5C1C108
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the RssB family.
messages: Binds to RpoS.
messages: Phosphorylated. Phosphorylation stimulates the interaction with RpoS and, therefore, the proteolysis of RpoS.
messages: Regulates the turnover of the sigma S factor (RpoS) by promoting its proteolysis in exponentially growing cells. Acts by binding and delivering RpoS to the ClpXP protease. RssB is not co-degraded with RpoS, but is released from the complex and can initiate a new cycle of RpoS recognition and degradation.

2494701:FY206 RS08170
gene id: 2494701:FY206_RS08170
uniprot id: A0A5C1BXU4
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

2494701:FY206 RS21345
gene id: 2494701:FY206_RS21345
uniprot id: A0A5C1C488
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fimbrial export usher family.
messages: Cell outer membrane
messages: Membrane

2494701:FY206 RS14765
gene id: 2494701:FY206_RS14765
uniprot id: A0A5C1C2E7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Cx-SAM synthase family.
messages: Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM).
messages: Homodimer.

2494701:FY206 RS08125
gene id: 2494701:FY206_RS08125
uniprot id: A0A5C1BXK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane OOP (TC 1.B.6) superfamily. OmpX family.
messages: Cell outer membrane

2494701:FY206 RS05740
gene id: 2494701:FY206_RS05740
uniprot id: A0A5C1C745
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HdeB family.
messages: Periplasm
messages: Required for optimal acid stress protection, which is important for survival of enteric bacteria in the acidic environment of the host stomach. Exhibits a chaperone-like activity at acidic pH by preventing the aggregation of many different periplasmic proteins.

2494701:FY206 RS03960
gene id: 2494701:FY206_RS03960
uniprot id: A0A5C1BVL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell inner membrane
messages: Membrane

2494701:FY206 RS13945
gene id: 2494701:FY206_RS13945
uniprot id: A0A5C1C1H9
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

2494701:FY206 RS22870
gene id: 2494701:FY206_RS22870
uniprot id: A0A5C1C6Q3
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

2494701:FY206 RS07300
gene id: 2494701:FY206_RS07300
uniprot id: A0A5C1BXX2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the lipid A palmitoyltransferase family.
messages: Cell outer membrane
messages: Homodimer.
messages: Transfers a palmitate residue from the sn-1 position of a phospholipid to the N-linked hydroxymyristate on the proximal unit of lipid A or its precursors.

2494701:FY206 RS09320
gene id: 2494701:FY206_RS09320
uniprot id: A0A5C1BYQ2
names: Caution
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the porin LamB (TC 1.B.3) family.
messages: By maltose.
messages: Cell outer membrane
messages: Homotrimer formed of three 18-stranded antiparallel beta-barrels, containing three independent channels.
messages: Involved in the transport of maltose and maltodextrins.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

2494701:FY206 RS20905
gene id: 2494701:FY206_RS20905
uniprot id: A0A5C1C4H4
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

2494701:FY206 RS00175
gene id: 2494701:FY206_RS00175
uniprot id: A0A5C1BUU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family.
messages: Membrane

2494701:FY206 RS03470
gene id: 2494701:FY206_RS03470
uniprot id: A0A5C1BVD5
names: Similarity
messages: Belongs to the HsdR family.

2494701:FY206 RS00805
gene id: 2494701:FY206_RS00805
uniprot id: A0A5C1BV66
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

2494701:FY206 RS05060
gene id: 2494701:FY206_RS05060
uniprot id: A0A5C1BWG9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

2494701:FY206 RS08290
gene id: 2494701:FY206_RS08290
uniprot id: A0A5C1BY79
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

2494701:FY206 RS01155
gene id: 2494701:FY206_RS01155
uniprot id: A0A5C1BU65
names: Cofactor
messages: Binds 1 Mg(2+) ion per trimer.

2494701:FY206 RS16565
gene id: 2494701:FY206_RS16565
uniprot id: A0A5C1C3B0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2494701:FY206 RS13110
gene id: 2494701:FY206_RS13110
uniprot id: A0A5C1C064
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

2494701:FY206 RS22845
gene id: 2494701:FY206_RS22845
uniprot id: A0A5C1C5H2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. Carboxylesterase BioH family.
messages: Cytoplasm
messages: Monomer.
messages: The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters.

2494701:FY206 RS00105
gene id: 2494701:FY206_RS00105
uniprot id: A0A5C1BTF2
names: Subcellular Location Annotation
messages: Membrane

2494701:FY206 RS11655
gene id: 2494701:FY206_RS11655
uniprot id: A0A5C1BZT5
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

2494701:FY206 RS00665
gene id: 2494701:FY206_RS00665
uniprot id: A0A5C1BTT3
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily.
messages: Binds 1 NADP(+) per subunit.
messages: Catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose.
messages: Contains a large N-terminal NADP-binding domain, and a smaller C-terminal substrate-binding domain.
messages: Homopentamer.

2494701:FY206 RS21390
gene id: 2494701:FY206_RS21390
uniprot id: A0A5C1C497
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

2494701:FY206 RS07745
gene id: 2494701:FY206_RS07745
uniprot id: A0A5C1BYN6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Pal lipoprotein family.
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

2494701:FY206 RS24295
gene id: 2494701:FY206_RS24295
uniprot id: A0A5C1C652
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

2494701:FY206 RS22530
gene id: 2494701:FY206_RS22530
uniprot id: A0A5C1C5B7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

2494701:FY206 RS07580
gene id: 2494701:FY206_RS07580
uniprot id: A0A5C1BYL5
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-I family.

2494701:FY206 RS17960
gene id: 2494701:FY206_RS17960
uniprot id: A0A5C1C6S2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TmcA family.
messages: Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: nucleolus

2494701:FY206 RS11700
gene id: 2494701:FY206_RS11700
uniprot id: A0A5C1BZT6
names: Cofactor
names: PTM
names: Similarity
messages: Belongs to the copper/topaquinone oxidase family.
messages: Contains 1 topaquinone per subunit.
messages: Topaquinone (TPQ) is generated by copper-dependent autoxidation of a specific tyrosyl residue.

2494701:FY206 RS15730
gene id: 2494701:FY206_RS15730
uniprot id: A0A5C1C1I2
names: Function
names: Similarity
messages: Belongs to the vsr family.
messages: May nick specific sequences that contain T:G mispairs resulting from m5C-deamination.

2494701:FY206 RS10015
gene id: 2494701:FY206_RS10015
uniprot id: A0A5C1BYZ4
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

2494701:FY206 RS23210
gene id: 2494701:FY206_RS23210
uniprot id: A0A5C1C5P1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RlmJ family.
messages: Monomer.
messages: Specifically methylates the adenine in position 2030 of 23S rRNA.

2494701:FY206 RS06650
gene id: 2494701:FY206_RS06650
uniprot id: A0A5C1BXC9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxH family.
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.
messages: Binds 2 Mn(2+) ions per subunit in a binuclear metal center.
messages: Cell inner membrane
messages: Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

2494701:FY206 RS00810
gene id: 2494701:FY206_RS00810
uniprot id: A0A5C1BUB0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2494701:FY206 RS02505
gene id: 2494701:FY206_RS02505
uniprot id: A0A5C1BUU6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FrdD family.
messages: Cell membrane
messages: Part of an enzyme complex containing four subunits: a flavoprotein (FrdA), an iron-sulfur protein (FrdB), and two hydrophobic anchor proteins (FrdC and FrdD).
messages: Two distinct, membrane-bound, FAD-containing enzymes are responsible for the catalysis of fumarate and succinate interconversion; fumarate reductase is used in anaerobic growth, and succinate dehydrogenase is used in aerobic growth. Anchors the catalytic components of the fumarate reductase complex to the cell inner membrane, binds quinones.

2494701:FY206 RS21075
gene id: 2494701:FY206_RS21075
uniprot id: A0A5C1C4K4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell membrane
messages: Probably interacts with PlsX.

2494701:FY206 RS16840
gene id: 2494701:FY206_RS16840
uniprot id: A0A5C1C2N5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

2494701:FY206 RS21715
gene id: 2494701:FY206_RS21715
uniprot id: A0A5C1C4V0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

2494701:FY206 RS14830
gene id: 2494701:FY206_RS14830
uniprot id: A0A5C1C140
names: Function
messages: Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP.

2494701:FY206 RS03790
gene id: 2494701:FY206_RS03790
uniprot id: A0A5C1BVT6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphopentomutase family.
messages: Binds 1 or 2 manganese ions.
messages: Cytoplasm
messages: Phosphotransfer between the C1 and C5 carbon atoms of pentose.

2494701:FY206 RS22390
gene id: 2494701:FY206_RS22390
uniprot id: A0A5C1C561
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

2494701:FY206 RS13530
gene id: 2494701:FY206_RS13530
uniprot id: A0A5C1C0F1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2494701:FY206 RS07110
gene id: 2494701:FY206_RS07110
uniprot id: A0A5C1BXL0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thioesterase PaaI family.
messages: Cytoplasm
messages: Homotetramer. Dimer of dimers. Interacts specifically with the aryl carrier protein (ArCP) domain of EntB.
messages: Required for optimal enterobactin synthesis. Acts as a proofreading enzyme that prevents EntB misacylation by hydrolyzing the thioester bound existing between EntB and wrongly charged molecules.

2494701:FY206 RS09805
gene id: 2494701:FY206_RS09805
uniprot id: A0A5C1BZA9
names: Function
names: Similarity
messages: Belongs to the FlgN family.
messages: Required for the efficient initiation of filament assembly.

2494701:FY206 RS10310
gene id: 2494701:FY206_RS10310
uniprot id: A0A5C1BYV0
names: Cofactor
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Binds 1 zinc ion per subunit. The zinc ion is important for the structural integrity of the protein.

2494701:FY206 RS08725
gene id: 2494701:FY206_RS08725
uniprot id: A0A5C1BYF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Membrane

2494701:FY206 RS10555
gene id: 2494701:FY206_RS10555
uniprot id: A0A5C1BZN3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-3 family.
messages: Cytoplasm
messages: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
messages: Monomer.

2494701:FY206 RS04075
gene id: 2494701:FY206_RS04075
uniprot id: A0A5C1BVN5
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

2494701:FY206 RS18675
gene id: 2494701:FY206_RS18675
uniprot id: A0A5C1C493
names: Subcellular Location Annotation
messages: Membrane

2494701:FY206 RS23905
gene id: 2494701:FY206_RS23905
uniprot id: A0A5C1C5Y9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm

2494701:FY206 RS12885
gene id: 2494701:FY206_RS12885
uniprot id: A0A5C1C0R5
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

2494701:FY206 RS17435
gene id: 2494701:FY206_RS17435
uniprot id: A0A5C1C3R3
names: Similarity
messages: Belongs to the MlaA family.

2494701:FY206 RS02655
gene id: 2494701:FY206_RS02655
uniprot id: A0A5C1BUY7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

2494701:FY206 RS22950
gene id: 2494701:FY206_RS22950
uniprot id: A0A5C1C5J2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DcrB family.
messages: Cell membrane
messages: Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis. Essential for lipoprotein maturation under conditions where membrane fluidity may be altered.

2494701:FY206 RS17130
gene id: 2494701:FY206_RS17130
uniprot id: A0A5C1C3L2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

2494701:FY206 RS22565
gene id: 2494701:FY206_RS22565
uniprot id: A0A5C1C6E5
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

2494701:FY206 RS11600
gene id: 2494701:FY206_RS11600
uniprot id: A0A5C1C031
names: Similarity
messages: Belongs to the UPF0482 family.

2494701:FY206 RS18320
gene id: 2494701:FY206_RS18320
uniprot id: A0A5C1C397
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

2494701:FY206 RS00235
gene id: 2494701:FY206_RS00235
uniprot id: A0A5C1BTZ1
names: Similarity
messages: Belongs to the porin LamB (TC 1.B.3) family.

2494701:FY206 RS01780
gene id: 2494701:FY206_RS01780
uniprot id: A0A5C1BUK2
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

2494701:FY206 RS17200
gene id: 2494701:FY206_RS17200
uniprot id: A0A5C1C2V4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

2494701:FY206 RS18570
gene id: 2494701:FY206_RS18570
uniprot id: A0A5C1C472
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

2494701:FY206 RS06240
gene id: 2494701:FY206_RS06240
uniprot id: A0A5C1BX54
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Heterooctamer of two A chains, two B chains, two C chains and two D chains.
messages: Membrane

2494701:FY206 RS16235
gene id: 2494701:FY206_RS16235
uniprot id: A0A5C1C1S0
names: Similarity
messages: Belongs to the phosphohexose mutase family.

2494701:FY206 RS07510
gene id: 2494701:FY206_RS07510
uniprot id: A0A5C1BXT3
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

2494701:FY206 RS18315
gene id: 2494701:FY206_RS18315
uniprot id: A0A5C1C2W9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA.
messages: Cytoplasm
messages: Homodimer.

2494701:FY206 RS04050
gene id: 2494701:FY206_RS04050
uniprot id: A0A5C1BW98
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

2494701:FY206 RS04805
gene id: 2494701:FY206_RS04805
uniprot id: A0A5C1BWC7
names: Function
names: Similarity
messages: Belongs to the LpxB family.
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

2494701:FY206 RS07915
gene id: 2494701:FY206_RS07915
uniprot id: A0A5C1BXP2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
messages: Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
messages: Homodimer.

2494701:FY206 RS10095
gene id: 2494701:FY206_RS10095
uniprot id: A0A5C1BZ68
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3.A.1.125) family.
messages: Cell inner membrane
messages: Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.
messages: The complex is composed of two ATP-binding proteins (LolD) and two transmembrane proteins (LolC and LolE).

2494701:FY206 RS22930
gene id: 2494701:FY206_RS22930
uniprot id: A0A5C1C6L4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Membrane

2494701:FY206 RS24450
gene id: 2494701:FY206_RS24450
uniprot id: A0A5C1C5Y6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbsD / FucU family. RbsD subfamily.
messages: Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose.
messages: Cytoplasm
messages: Homodecamer.

2494701:FY206 RS00935
gene id: 2494701:FY206_RS00935
uniprot id: A0A5C1BUV0
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Catalyzes the phosphorylation of D-xylulose to D-xylulose 5-phosphate.

2494701:FY206 RS19880
gene id: 2494701:FY206_RS19880
uniprot id: A0A5C1C3W2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

2494701:FY206 RS04110
gene id: 2494701:FY206_RS04110
uniprot id: A0A5C1BVZ6
names: Domain
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cell inner membrane
messages: Homodimer.
messages: Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB/RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host.
messages: The transmembrane domain is a dimerization domain.

2494701:FY206 RS14685
gene id: 2494701:FY206_RS14685
uniprot id: A0A5C1C2A6
names: Similarity
messages: Belongs to the pyruvate kinase family.

2494701:FY206 RS10500
gene id: 2494701:FY206_RS10500
uniprot id: A0A5C1BZM5
names: Subcellular Location Annotation
messages: Membrane

2494701:FY206 RS01890
gene id: 2494701:FY206_RS01890
uniprot id: A0A5C1BVR9
names: Similarity
messages: Belongs to the YjdM family.

2494701:FY206 RS21100
gene id: 2494701:FY206_RS21100
uniprot id: A0A5C1C5V3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease gamma subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

2494701:FY206 RS05110
gene id: 2494701:FY206_RS05110
uniprot id: A0A5C1BWH9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

2494701:FY206 RS02760
gene id: 2494701:FY206_RS02760
uniprot id: A0A5C1BW57
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RIC family. YtfE subfamily.
messages: Cytoplasm
messages: Di-iron-containing protein involved in the repair of iron-sulfur clusters damaged by oxidative and nitrosative stress conditions.
messages: Homodimer.

2494701:FY206 RS19590
gene id: 2494701:FY206_RS19590
uniprot id: A0A5C1C555
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2494701:FY206 RS18380
gene id: 2494701:FY206_RS18380
uniprot id: A0A5C1C3D7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: In the N-terminal section; belongs to the FGAMS family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.

2494701:FY206 RS00495
gene id: 2494701:FY206_RS00495
uniprot id: A0A5C1BU37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

2494701:FY206 RS24375
gene id: 2494701:FY206_RS24375
uniprot id: A0A5C1C5X7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response.
messages: Belongs to the SrkA/RdoA protein kinase family.
messages: Cytoplasm
messages: Monomer.

2494701:FY206 RS10470
gene id: 2494701:FY206_RS10470
uniprot id: A0A5C1BZY2
names: Cofactor
messages: Binds 1 Mg(2+) ion per trimer.

2494701:FY206 RS20510
gene id: 2494701:FY206_RS20510
uniprot id: A0A5C1C5K6
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

2494701:FY206 RS21755
gene id: 2494701:FY206_RS21755
uniprot id: A0A5C1C4T6
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

2494701:FY206 RS14660
gene id: 2494701:FY206_RS14660
uniprot id: A0A5C1C2A3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Homodimer.
messages: Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate.

2494701:FY206 RS15680
gene id: 2494701:FY206_RS15680
uniprot id: A0A5C1C1G8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane
messages: Required for the assembly of the rivet at the earliest stage of flagellar biosynthesis.
messages: Role in flagellar biosynthesis.

2494701:FY206 RS04605
gene id: 2494701:FY206_RS04605
uniprot id: A0A5C1BVY3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DksA family.
messages: Cytoplasm
messages: Interacts directly with the RNA polymerase.
messages: Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression.

2494701:FY206 RS13615
gene id: 2494701:FY206_RS13615
uniprot id: A0A5C1C0H7
names: Similarity
messages: Belongs to the SUI1 family.

2494701:FY206 RS08000
gene id: 2494701:FY206_RS08000
uniprot id: A0A5C1BY86
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

2494701:FY206 RS15650
gene id: 2494701:FY206_RS15650
uniprot id: A0A5C1C2U9
names: Function
names: Similarity
messages: Belongs to the FliK family.
messages: Controls the length of the flagellar hook.

2494701:FY206 RS12580
gene id: 2494701:FY206_RS12580
uniprot id: A0A5C1C080
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Member of a two-component regulatory system.

2494701:FY206 RS23605
gene id: 2494701:FY206_RS23605
uniprot id: A0A5C1C6Z7
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Involved in a late step of protoheme IX synthesis.
messages: Membrane

2494701:FY206 RS01980
gene id: 2494701:FY206_RS01980
uniprot id: A0A5C1BUP1
names: Similarity
messages: Belongs to the YeeT/YkfH/YpjJ family.

2494701:FY206 RS23110
gene id: 2494701:FY206_RS23110
uniprot id: A0A5C1C5I6
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

2494701:FY206 RS22915
gene id: 2494701:FY206_RS22915
uniprot id: A0A5C1C554
names: Function
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.
messages: Removes maltotriose and maltotetraose chains that are attached by 1,6-alpha-linkage to the limit dextrin main chain, generating a debranched limit dextrin.

2494701:FY206 RS01065
gene id: 2494701:FY206_RS01065
uniprot id: A0A5C1BU67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

2494701:FY206 RS02265
gene id: 2494701:FY206_RS02265
uniprot id: A0A5C1BV38
names: Subcellular Location Annotation
messages: Membrane

2494701:FY206 RS24120
gene id: 2494701:FY206_RS24120
uniprot id: A0A5C1C5Q3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the aldolase class II family. RhaD subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the reversible cleavage of L-rhamnulose-1-phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde.
messages: Cytoplasm
messages: Homotetramer.

2494701:FY206 RS02725
gene id: 2494701:FY206_RS02725
uniprot id: A0A5C1BUY1
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

2494701:FY206 RS12555
gene id: 2494701:FY206_RS12555
uniprot id: A0A5C1C6P7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

2494701:FY206 RS16995
gene id: 2494701:FY206_RS16995
uniprot id: A0A5C1C2F1
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
messages: O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.

2494701:FY206 RS14665
gene id: 2494701:FY206_RS14665
uniprot id: A0A5C1C1B9
names: Similarity
names: Subunit
messages: Belongs to the KHG/KDPG aldolase family.
messages: Homotrimer.

2494701:FY206 RS07880
gene id: 2494701:FY206_RS07880
uniprot id: A0A5C1BXW6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the arginase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide.

2494701:FY206 RS09815
gene id: 2494701:FY206_RS09815
uniprot id: A0A5C1BZ22
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FlgA family.
messages: Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly.
messages: Periplasm

2494701:FY206 RS17395
gene id: 2494701:FY206_RS17395
uniprot id: A0A5C1C2T0
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmB subfamily.
messages: Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue.

2494701:FY206 RS21005
gene id: 2494701:FY206_RS21005
uniprot id: A0A5C1C482
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZIP transporter (TC 2.A.5) family. ZupT subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mediates zinc uptake. May also transport other divalent cations.
messages: Membrane

2494701:FY206 RS12285
gene id: 2494701:FY206_RS12285
uniprot id: A0A5C1BZS3
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

2494701:FY206 RS17025
gene id: 2494701:FY206_RS17025
uniprot id: A0A5C1C2Z6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Composed of a catalytic GlpA/B dimer and of membrane bound GlpC.
messages: Membrane

2494701:FY206 RS23820
gene id: 2494701:FY206_RS23820
uniprot id: A0A5C1C5J3
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. TrmA subfamily.
messages: Dual-specificity methyltransferase that catalyzes the formation of 5-methyluridine at position 54 (m5U54) in all tRNAs, and that of position 341 (m5U341) in tmRNA (transfer-mRNA).

2494701:FY206 RS11460
gene id: 2494701:FY206_RS11460
uniprot id: A0A5C1BZK5
names: Similarity
messages: Belongs to the ABC transporter superfamily.

2494701:FY206 RS09790
gene id: 2494701:FY206_RS09790
uniprot id: A0A5C1BYI8
names: Similarity
messages: Belongs to the UPF0502 family.

2494701:FY206 RS03055
gene id: 2494701:FY206_RS03055
uniprot id: A0A5C1BVU0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

2494701:FY206 RS00445
gene id: 2494701:FY206_RS00445
uniprot id: A0A5C1BU28
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

2494701:FY206 RS18305
gene id: 2494701:FY206_RS18305
uniprot id: A0A5C1C4K5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
messages: Cytoplasm
messages: Homodimer. Forms a heterotetramer with IscU, interacts with other sulfur acceptors.
messages: Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.

2494701:FY206 RS18970
gene id: 2494701:FY206_RS18970
uniprot id: A0A5C1C3D5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2494701:FY206 RS18390
gene id: 2494701:FY206_RS18390
uniprot id: A0A5C1C372
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: In the C-terminal section; belongs to the transglycosylase Slt family.
messages: In the N-terminal section; belongs to the bacterial solute-binding protein 3 family.
messages: Membrane
messages: Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella.
messages: The N-terminal domain does not have lytic activity and probably modulates enzymatic activity. The C-terminal domain is the catalytic active domain.

2494701:FY206 RS08750
gene id: 2494701:FY206_RS08750
uniprot id: A0A5C1BY15
names: Function
messages: Electron transfer subunit of the terminal reductase during anaerobic growth on various sulfoxide and N-oxide compounds.

2494701:FY206 RS10185
gene id: 2494701:FY206_RS10185
uniprot id: A0A5C1BZ16
names: Similarity
names: Subunit
messages: Belongs to the Nudix hydrolase family. NudJ subfamily.
messages: Monomer.

2494701:FY206 RS07370
gene id: 2494701:FY206_RS07370
uniprot id: A0A5C1BX77
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein L14 (rplN).

2494701:FY206 RS01395
gene id: 2494701:FY206_RS01395
uniprot id: A0A5C1BUA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

2494701:FY206 RS16970
gene id: 2494701:FY206_RS16970
uniprot id: A0A5C1C2Y8
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the RcsB family.
messages: Component of the Rcs signaling system, which controls transcription of numerous genes. RcsB is the response regulator that binds to regulatory DNA regions.
messages: Interacts with RcsD.
messages: Phosphorylated and activated by RcsD.

2494701:FY206 RS04880
gene id: 2494701:FY206_RS04880
uniprot id: A0A5C1BX99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nlpA lipoprotein family.
messages: Membrane

2494701:FY206 RS16535
gene id: 2494701:FY206_RS16535
uniprot id: A0A5C1C3A3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.

2494701:FY206 RS21080
gene id: 2494701:FY206_RS21080
uniprot id: A0A5C1C5A8
names: Subcellular Location Annotation
messages: Membrane

2494701:FY206 RS03335
gene id: 2494701:FY206_RS03335
uniprot id: A0A5C1BV93
names: Subcellular Location Annotation
messages: Membrane

2494701:FY206 RS03995
gene id: 2494701:FY206_RS03995
uniprot id: A0A5C1BW92
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

2494701:FY206 RS04340
gene id: 2494701:FY206_RS04340
uniprot id: A0A5C1BVT5
names: Similarity
messages: Belongs to the Nudix hydrolase family.

2494701:FY206 RS06015
gene id: 2494701:FY206_RS06015
uniprot id: A0A5C1BWM8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

2494701:FY206 RS08095
gene id: 2494701:FY206_RS08095
uniprot id: A0A5C1BXY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

2494701:FY206 RS15785
gene id: 2494701:FY206_RS15785
uniprot id: A0A5C1C1J4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2494701:FY206 RS08225
gene id: 2494701:FY206_RS08225
uniprot id: A0A5C1BXM8
names: Similarity
messages: Belongs to the organic radical-activating enzymes family.

2494701:FY206 RS09290
gene id: 2494701:FY206_RS09290
uniprot id: A0A5C1BYP4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 1 family.
messages: Part of the ABC transporter complex MalEFGK involved in maltose/maltodextrin import. Binds maltose and higher maltodextrins.
messages: Periplasm

2494701:FY206 RS14025
gene id: 2494701:FY206_RS14025
uniprot id: A0A5C1C0Y1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2494701:FY206 RS08175
gene id: 2494701:FY206_RS08175
uniprot id: A0A5C1BXL5
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane.

2494701:FY206 RS24535
gene id: 2494701:FY206_RS24535
uniprot id: A0A5C1C6C8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

2494701:FY206 RS16120
gene id: 2494701:FY206_RS16120
uniprot id: A0A5C1C2I2
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the PRA-PH family.
messages: In the N-terminal section; belongs to the PRA-CH family.

2494701:FY206 RS18140
gene id: 2494701:FY206_RS18140
uniprot id: A0A5C1C325
names: Similarity
messages: Belongs to the TPP enzyme family.

2494701:FY206 RS07500
gene id: 2494701:FY206_RS07500
uniprot id: A0A5C1BY03
names: Similarity
messages: Belongs to the asparagine synthetase family.

2494701:FY206 RS00180
gene id: 2494701:FY206_RS00180
uniprot id: A0A5C1BTX9
names: Subcellular Location Annotation
messages: Membrane

2494701:FY206 RS02495
gene id: 2494701:FY206_RS02495
uniprot id: A0A5C1C6D6
names: Function
names: Similarity
messages: Belongs to the class-C beta-lactamase family.
messages: This protein is a serine beta-lactamase with a substrate specificity for cephalosporins.

2494701:FY206 RS22295
gene id: 2494701:FY206_RS22295
uniprot id: A0A5C1C4R3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).

2494701:FY206 RS03940
gene id: 2494701:FY206_RS03940
uniprot id: A0A5C1BVT8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

2494701:FY206 RS16165
gene id: 2494701:FY206_RS16165
uniprot id: A0A5C1C1Q8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

2494701:FY206 RS09335
gene id: 2494701:FY206_RS09335
uniprot id: A0A5C1BY94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell inner membrane
messages: Membrane

2494701:FY206 RS06125
gene id: 2494701:FY206_RS06125
uniprot id: A0A5C1BWY9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

2494701:FY206 RS01465
gene id: 2494701:FY206_RS01465
uniprot id: A0A5C1BVI8
names: Similarity
messages: Belongs to the leucine-binding protein family.

2494701:FY206 RS08970
gene id: 2494701:FY206_RS08970
uniprot id: A0A5C1BYG6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCF family. Uup subfamily.
messages: Cytoplasm
messages: Probably plays a role in ribosome assembly or function. May be involved in resolution of branched DNA intermediates that result from template switching in postreplication gaps. Binds DNA and has ATPase activity.

2494701:FY206 RS21705
gene id: 2494701:FY206_RS21705
uniprot id: A0A5C1C4X3
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

2494701:FY206 RS06850
gene id: 2494701:FY206_RS06850
uniprot id: A0A5C1BX31
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

2494701:FY206 RS16770
gene id: 2494701:FY206_RS16770
uniprot id: A0A5C1C3E4
names: Function
names: Similarity
messages: Belongs to the mannonate dehydratase family.
messages: Catalyzes the dehydration of D-mannonate.

2494701:FY206 RS01150
gene id: 2494701:FY206_RS01150
uniprot id: A0A5C1BU86
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

2494701:FY206 RS22725
gene id: 2494701:FY206_RS22725
uniprot id: A0A5C1C6H4
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

2494701:FY206 RS21675
gene id: 2494701:FY206_RS21675
uniprot id: A0A5C1C646
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid/polyamine transporter 2 family. Mtr/TnaB/TyrP permease subfamily.
messages: Cell inner membrane
messages: Involved in transporting aromatic amino acids across the cytoplasmic membrane.
messages: Membrane

2494701:FY206 RS04615
gene id: 2494701:FY206_RS04615
uniprot id: A0A5C1BX50
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

2494701:FY206 RS09330
gene id: 2494701:FY206_RS09330
uniprot id: A0A5C1BYE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC41A transporter family.
messages: Membrane

2494701:FY206 RS09045
gene id: 2494701:FY206_RS09045
uniprot id: A0A5C1BYA3
names: Similarity
messages: Belongs to the UPF0319 family.

2494701:FY206 RS17150
gene id: 2494701:FY206_RS17150
uniprot id: A0A5C1C2U4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cell membrane
messages: In the C-terminal section; belongs to the complex I 49 kDa subunit family.
messages: In the N-terminal section; belongs to the complex I 30 kDa subunit family.
messages: NDH-1 is composed of 13 different subunits. Subunits NuoB, CD, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

2494701:FY206 RS08875
gene id: 2494701:FY206_RS08875
uniprot id: A0A5C1BYJ1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family. MukB subfamily.
messages: Homodimerization via its hinge domain. Binds to DNA via its C-terminal region. Interacts, and probably forms a ternary complex, with MukE and MukF via its C-terminal region. The complex formation is stimulated by calcium or magnesium. Interacts with tubulin-related protein FtsZ.
messages: Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division.
messages: The hinge domain, which separates the large intramolecular coiled coil regions, allows the homodimerization, forming a V-shaped homodimer.
messages: nucleoid

2494701:FY206 RS07040
gene id: 2494701:FY206_RS07040
uniprot id: A0A5C1BXG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

2494701:FY206 RS23460
gene id: 2494701:FY206_RS23460
uniprot id: A0A5C1C5S2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiJ family.
messages: Cytoplasm
messages: Required for ubiquinone (coenzyme Q) biosynthesis. Binds hydrophobic ubiquinone biosynthetic intermediates via its SCP2 domain and is essential for the stability of the Ubi complex. May constitute a docking platform where Ubi enzymes assemble and access their SCP2-bound polyprenyl substrates.

2494701:FY206 RS12475
gene id: 2494701:FY206_RS12475
uniprot id: A0A5C1BZX2
names: Subcellular Location Annotation
messages: Cell inner membrane

2494701:FY206 RS10595
gene id: 2494701:FY206_RS10595
uniprot id: A0A5C1BZ15
names: Function
names: Similarity
messages: Belongs to the glutathione peroxidase family. BtuE subfamily.
messages: Non-specific peroxidase that can use thioredoxin or glutathione as a reducing agent.

2494701:FY206 RS23705
gene id: 2494701:FY206_RS23705
uniprot id: A0A5C1C5W0
names: Function
names: Similarity
messages: Belongs to the GppA/Ppx family. GppA subfamily.
messages: Catalyzes the conversion of pppGpp to ppGpp. Guanosine pentaphosphate (pppGpp) is a cytoplasmic signaling molecule which together with ppGpp controls the 'stringent response', an adaptive process that allows bacteria to respond to amino acid starvation, resulting in the coordinated regulation of numerous cellular activities.

2494701:FY206 RS17020
gene id: 2494701:FY206_RS17020
uniprot id: A0A5C1C275
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family.
messages: Membrane

2494701:FY206 RS24630
gene id: 2494701:FY206_RS24630
uniprot id: A0A5C1C6B6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

2494701:FY206 RS22540
gene id: 2494701:FY206_RS22540
uniprot id: A0A5C1C585
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DsrF/TusC family.
messages: Cytoplasm
messages: Heterohexamer, formed by a dimer of trimers. The hexameric TusBCD complex contains 2 copies each of TusB, TusC and TusD. The TusBCD complex interacts with TusE.
messages: Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions.

2494701:FY206 RS11105
gene id: 2494701:FY206_RS11105
uniprot id: A0A5C1BZI7
names: Similarity
messages: Belongs to the Hha/YmoA/Cnu family.

2494701:FY206 RS18935
gene id: 2494701:FY206_RS18935
uniprot id: A0A5C1C381
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

2494701:FY206 RS25165
gene id: 2494701:FY206_RS25165
uniprot id: A0A5C1C750
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

2494701:FY206 RS14115
gene id: 2494701:FY206_RS14115
uniprot id: A0A5C1C1K8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

2494701:FY206 RS07790
gene id: 2494701:FY206_RS07790
uniprot id: A0A5C1BXT9
names: Subcellular Location Annotation
messages: Membrane

2494701:FY206 RS07130
gene id: 2494701:FY206_RS07130
uniprot id: A0A5C1BXI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

2494701:FY206 RS23550
gene id: 2494701:FY206_RS23550
uniprot id: A0A5C1C6Z1
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

2494701:FY206 RS22430
gene id: 2494701:FY206_RS22430
uniprot id: A0A5C1C597
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

2494701:FY206 RS19230
gene id: 2494701:FY206_RS19230
uniprot id: A0A5C1C3C6
names: Function
names: Similarity
messages: Belongs to the carbamoyltransferase HypF family.
messages: Involved in the maturation of [NiFe] hydrogenases. Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of [NiFe]-hydrogenases. HypF functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide.

2494701:FY206 RS04210
gene id: 2494701:FY206_RS04210
uniprot id: A0A5C1BWD2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

2494701:FY206 RS24320
gene id: 2494701:FY206_RS24320
uniprot id: A0A5C1C672
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glutamine synthetase family.
messages: Catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia.
messages: Cytoplasm
messages: Oligomer of 12 subunits arranged in the form of two hexagons.

2494701:FY206 RS11220
gene id: 2494701:FY206_RS11220
uniprot id: A0A5C1BZL5
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

2494701:FY206 RS07330
gene id: 2494701:FY206_RS07330
uniprot id: A0A5C1BXM7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2494701:FY206 RS07595
gene id: 2494701:FY206_RS07595
uniprot id: A0A5C1BXP6
names: Subcellular Location Annotation
messages: Membrane

2494701:FY206 RS08680
gene id: 2494701:FY206_RS08680
uniprot id: A0A5C1BY42
names: Similarity
messages: Belongs to the MbcT/ParT/Res family.

2494701:FY206 RS14030
gene id: 2494701:FY206_RS14030
uniprot id: A0A5C1C193
names: Similarity
messages: Belongs to the CmpA/NrtA family.

2494701:FY206 RS07190
gene id: 2494701:FY206_RS07190
uniprot id: A0A5C1BXH9
names: Function
names: Similarity
messages: Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).

2494701:FY206 RS23920
gene id: 2494701:FY206_RS23920
uniprot id: A0A5C1C5L4
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the peroxidase family. Peroxidase/catalase subfamily.
messages: Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.
messages: Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.
messages: Homodimer or homotetramer.

2494701:FY206 RS09860
gene id: 2494701:FY206_RS09860
uniprot id: A0A5C1BYZ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Flagellum-specific muramidase which hydrolyzes the peptidoglycan layer to assemble the rod structure in the periplasmic space.
messages: In the C-terminal section; belongs to the glycosyl hydrolase 73 family.
messages: In the N-terminal section; belongs to the FlgJ family.
messages: Periplasm

2494701:FY206 RS11370
gene id: 2494701:FY206_RS11370
uniprot id: A0A5C1BZP1
names: Similarity
messages: Belongs to the peptidase S1B family.

2494701:FY206 RS13835
gene id: 2494701:FY206_RS13835
uniprot id: A0A5C1C0P0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YciB family.
messages: Cell inner membrane
messages: Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis.

2494701:FY206 RS14360
gene id: 2494701:FY206_RS14360
uniprot id: A0A5C1C249
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

2494701:FY206 RS10605
gene id: 2494701:FY206_RS10605
uniprot id: A0A5C1BZ91
names: Similarity
messages: Belongs to the peptidase C40 family.

2494701:FY206 RS22045
gene id: 2494701:FY206_RS22045
uniprot id: A0A5C1C509
names: Similarity
messages: Belongs to the peptidase S1C family.

2494701:FY206 RS14675
gene id: 2494701:FY206_RS14675
uniprot id: A0A5C1C117
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2494701:FY206 RS13205
gene id: 2494701:FY206_RS13205
uniprot id: A0A5C1C0X2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GhoT/OrtT toxin family.
messages: Cell inner membrane
messages: Membrane

2494701:FY206 RS24620
gene id: 2494701:FY206_RS24620
uniprot id: A0A5C1C7N5
names: Subcellular Location Annotation
messages: Membrane

2494701:FY206 RS02450
gene id: 2494701:FY206_RS02450
uniprot id: A0A5C1BV11
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

2494701:FY206 RS09300
gene id: 2494701:FY206_RS09300
uniprot id: A0A5C1BYK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2494701:FY206 RS03935
gene id: 2494701:FY206_RS03935
uniprot id: A0A5C1BVL3
names: Similarity
names: Subunit
messages: Homotetramer.
messages: In the C-terminal section; belongs to the homoserine dehydrogenase family.
messages: In the N-terminal section; belongs to the aspartokinase family.

2494701:FY206 RS23410
gene id: 2494701:FY206_RS23410
uniprot id: A0A5C1C5N6
names: Function
names: Similarity
names: Subunit
messages: Heterotetramer of two alpha chains (FadB) and two beta chains (FadA).
messages: In the C-terminal section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family.
messages: In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.
messages: Involved in the aerobic and anaerobic degradation of long-chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate.

2494701:FY206 RS16100
gene id: 2494701:FY206_RS16100
uniprot id: A0A5C1C326
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: In the N-terminal section; belongs to the histidinol-phosphatase family.

2494701:FY206 RS21925
gene id: 2494701:FY206_RS21925
uniprot id: A0A5C1C512
names: PTM
names: Subcellular Location Annotation
messages: Activation requires a sequential transfer of a phosphate group from a His in the primary transmitter domain, to an Asp in the receiver domain and to a His in the secondary transmitter domain.
messages: Cell inner membrane
messages: Membrane

2494701:FY206 RS21805
gene id: 2494701:FY206_RS21805
uniprot id: A0A5C1C500
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

2494701:FY206 RS20355
gene id: 2494701:FY206_RS20355
uniprot id: A0A5C1C447
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

2494701:FY206 RS18655
gene id: 2494701:FY206_RS18655
uniprot id: A0A5C1C332
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein S19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein S19.

2494701:FY206 RS15235
gene id: 2494701:FY206_RS15235
uniprot id: A0A5C1C252
names: Function
names: Similarity
names: Subunit
messages: Belongs to the rusA family.
messages: Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of CC dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of RuvAB or RuvC.
messages: Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC.
messages: Homodimer.

2494701:FY206 RS22135
gene id: 2494701:FY206_RS22135
uniprot id: A0A5C1C551
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

2494701:FY206 RS02140
gene id: 2494701:FY206_RS02140
uniprot id: A0A5C1BUR2
names: Subcellular Location Annotation
messages: Cell inner membrane

2494701:FY206 RS15625
gene id: 2494701:FY206_RS15625
uniprot id: A0A5C1C2U5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the FliF family.
messages: Membrane
messages: The M ring may be actively involved in energy transduction.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The M ring is integral to the inner membrane of the cell and may be connected to the flagellar rod via the S ring. The S (supramembrane ring) lies just distal to the M ring. The L and P rings lie in the outer membrane and the periplasmic space, respectively.

2494701:FY206 RS04255
gene id: 2494701:FY206_RS04255
uniprot id: A0A5C1BVS9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

2494701:FY206 RS22070
gene id: 2494701:FY206_RS22070
uniprot id: A0A5C1C540
names: Similarity
messages: Belongs to the barstar family.

2494701:FY206 RS21535
gene id: 2494701:FY206_RS21535
uniprot id: A0A5C1C4U4
names: Similarity
messages: Belongs to the UPF0597 family.

2494701:FY206 RS14450
gene id: 2494701:FY206_RS14450
uniprot id: A0A5C1C0V7
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

2494701:FY206 RS21710
gene id: 2494701:FY206_RS21710
uniprot id: A0A5C1C5K8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

2494701:FY206 RS24635
gene id: 2494701:FY206_RS24635
uniprot id: A0A5C1C5Y7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

2494701:FY206 RS16680
gene id: 2494701:FY206_RS16680
uniprot id: A0A5C1C2E5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial solute-binding protein 2 family.
messages: Periplasm
messages: The ABC transporter complex is composed of one ATP-binding protein (MglA), two transmembrane proteins (MglC) and a solute-binding protein (MglB).

2494701:FY206 RS04510
gene id: 2494701:FY206_RS04510
uniprot id: A0A5C1BVW1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm
messages: Purine salvage pathway enzyme which catalyzes the transfer of the ribosyl-5-phosphate group from 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to the N9 position of hypoxanthine to yield IMP (inosine 5'-monophosphate). To a lesser extent, can also act on guanine leading to GMP, but shows a highly less efficient activity with xanthine.

2494701:FY206 RS03990
gene id: 2494701:FY206_RS03990
uniprot id: A0A5C1BVV0
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

2494701:FY206 RS12715
gene id: 2494701:FY206_RS12715
uniprot id: A0A5C1C0F6
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

2494701:FY206 RS21060
gene id: 2494701:FY206_RS21060
uniprot id: A0A5C1C4K1
names: Cofactor
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A single active site specifically recognizes both ATP and CTP and is responsible for their addition.
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 1 subfamily.
messages: Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases.
messages: Comprises two domains: an N-terminal domain containing the nucleotidyltransferase activity and a C-terminal HD domain associated with both phosphodiesterase and phosphatase activities.
messages: Magnesium is required for nucleotidyltransferase activity.
messages: Monomer. Can also form homodimers and oligomers.
messages: Nickel for phosphatase activity.

2494701:FY206 RS18660
gene id: 2494701:FY206_RS18660
uniprot id: A0A5C1C3E5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

2494701:FY206 RS09255
gene id: 2494701:FY206_RS09255
uniprot id: A0A5C1BZ20
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

2494701:FY206 RS20545
gene id: 2494701:FY206_RS20545
uniprot id: A0A5C1C463
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

2494701:FY206 RS09405
gene id: 2494701:FY206_RS09405
uniprot id: A0A5C1BYL6
names: Function
names: Similarity
messages: Belongs to the RutC family.
messages: Involved in pyrimidine catabolism. Catalyzes the deamination of 3-aminoacrylate to malonic semialdehyde, a reaction that can also occur spontaneously. RutC may facilitate the reaction and modulate the metabolic fitness, rather than catalyzing essential functions.

2494701:FY206 RS06550
gene id: 2494701:FY206_RS06550
uniprot id: A0A5C1BXA5
names: Similarity
messages: Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.

2494701:FY206 RS20320
gene id: 2494701:FY206_RS20320
uniprot id: A0A5C1C3W0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

2494701:FY206 RS06420
gene id: 2494701:FY206_RS06420
uniprot id: A0A5C1BX67
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NiCoT transporter (TC 2.A.52) family. RcnA subfamily.
messages: Cell membrane
messages: Efflux system for nickel and cobalt.
messages: Membrane

2494701:FY206 RS04740
gene id: 2494701:FY206_RS04740
uniprot id: A0A5C1BW24
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

2494701:FY206 RS23700
gene id: 2494701:FY206_RS23700
uniprot id: A0A5C1C5V4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DEAD box helicase family. RhlB subfamily.
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in RNA degradation. Has RNA-dependent ATPase activity and unwinds double-stranded RNA.

2494701:FY206 RS15610
gene id: 2494701:FY206_RS15610
uniprot id: A0A5C1C1H4
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

2494701:FY206 RS23510
gene id: 2494701:FY206_RS23510
uniprot id: A0A5C1C5S9
names: Similarity
messages: Belongs to the Rht family.

2494701:FY206 RS07340
gene id: 2494701:FY206_RS07340
uniprot id: A0A5C1BXK9
names: Similarity
messages: Belongs to the UPF0250 family.

2494701:FY206 RS15535
gene id: 2494701:FY206_RS15535
uniprot id: A0A5C1C209
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

2494701:FY206 RS19615
gene id: 2494701:FY206_RS19615
uniprot id: A0A5C1C3Z2
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

2494701:FY206 RS12560
gene id: 2494701:FY206_RS12560
uniprot id: A0A5C1BZW6
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

2494701:FY206 RS17060
gene id: 2494701:FY206_RS17060
uniprot id: A0A5C1C2I8
names: Caution
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
messages: Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2494701:FY206 RS22580
gene id: 2494701:FY206_RS22580
uniprot id: A0A5C1C504
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NAD(P)H dehydrogenase (quinone) family. KefG subfamily.
messages: Cell inner membrane
messages: Interacts with KefB.
messages: Regulatory subunit of a potassium efflux system that confers protection against electrophiles. Required for full activity of KefB.

2494701:FY206 RS01365
gene id: 2494701:FY206_RS01365
uniprot id: A0A5C1BUM2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 1 family.
messages: Part of the ABC transporter complex MalEFGK involved in maltose/maltodextrin import. Binds maltose and higher maltodextrins.
messages: Periplasm

2494701:FY206 RS11230
gene id: 2494701:FY206_RS11230
uniprot id: A0A5C1BZC3
names: Subcellular Location Annotation
messages: Cell inner membrane

2494701:FY206 RS10530
gene id: 2494701:FY206_RS10530
uniprot id: A0A5C1C803
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

2494701:FY206 RS19500
gene id: 2494701:FY206_RS19500
uniprot id: A0A5C1C3J0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoS subfamily.
messages: Cytoplasm
messages: Interacts with the RNA polymerase core enzyme.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the master transcriptional regulator of the stationary phase and the general stress response.

2494701:FY206 RS16355
gene id: 2494701:FY206_RS16355
uniprot id: A0A5C1C233
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. MdtC subfamily.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of a tripartite efflux system composed of MdtA, MdtB and MdtC. MdtC forms a heteromultimer with MdtB.

2494701:FY206 RS19795
gene id: 2494701:FY206_RS19795
uniprot id: A0A5C1C3T5
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild-type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity.
messages: Belongs to the RecC family.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding.

2494701:FY206 RS04705
gene id: 2494701:FY206_RS04705
uniprot id: A0A5C1BW75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1C family.
messages: Periplasm

2494701:FY206 RS23760
gene id: 2494701:FY206_RS23760
uniprot id: A0A5C1C5W9
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

2494701:FY206 RS12775
gene id: 2494701:FY206_RS12775
uniprot id: A0A5C1C0C8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 32 family.
messages: Cytoplasm
messages: Enables the bacterium to metabolize sucrose as a sole carbon source.

2494701:FY206 RS01580
gene id: 2494701:FY206_RS01580
uniprot id: A0A5C1BUH3
names: Similarity
messages: Belongs to the Fur family.

2494701:FY206 RS18345
gene id: 2494701:FY206_RS18345
uniprot id: A0A5C1C2W3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

2494701:FY206 RS21595
gene id: 2494701:FY206_RS21595
uniprot id: A0A5C1C4V4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

2494701:FY206 RS13680
gene id: 2494701:FY206_RS13680
uniprot id: A0A5C1C1U0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Cob(I)alamin adenosyltransferase family.
messages: Cytoplasm
messages: Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids.

2494701:FY206 RS15395
gene id: 2494701:FY206_RS15395
uniprot id: A0A5C1C867
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HsdR family.
messages: Subunit R is required for both nuclease and ATPase activities, but not for modification.
messages: The type I restriction/modification system is composed of three polypeptides R, M and S.

2494701:FY206 RS00880
gene id: 2494701:FY206_RS00880
uniprot id: A0A5C1BUU2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LDH2/MDH2 oxidoreductase family. DlgD subfamily.
messages: Catalyzes the reduction of 2,3-diketo-L-gulonate in the presence of NADH, to form 3-keto-L-gulonate.
messages: Cytoplasm
messages: Homodimer.

2494701:FY206 RS00295
gene id: 2494701:FY206_RS00295
uniprot id: A0A5C1BTJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nlpA lipoprotein family.
messages: Membrane

2494701:FY206 RS13575
gene id: 2494701:FY206_RS13575
uniprot id: A0A5C1C1S4
names: Function
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.
messages: Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP). Involved in the elongation cycle of fatty acid which are used in the lipid metabolism and in the biotin biosynthesis.

2494701:FY206 RS04205
gene id: 2494701:FY206_RS04205
uniprot id: A0A5C1BVZ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

2494701:FY206 RS15775
gene id: 2494701:FY206_RS15775
uniprot id: A0A5C1C2C9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. DIT1 subfamily.
messages: Membrane

2494701:FY206 RS19080
gene id: 2494701:FY206_RS19080
uniprot id: A0A5C1C4E4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homotetramer.

2494701:FY206 RS12415
gene id: 2494701:FY206_RS12415
uniprot id: A0A5C1C0C5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Cell inner membrane

2494701:FY206 RS07390
gene id: 2494701:FY206_RS07390
uniprot id: A0A5C1BXB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

2494701:FY206 RS24290
gene id: 2494701:FY206_RS24290
uniprot id: A0A5C1C7H5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the N-acylglucosamine 2-epimerase family.
messages: Catalyzes the isomerization of sulfoquinovose (SQ) to 6-deoxy-6-sulfo-D-fructose (SF).
messages: Homohexamer.

2494701:FY206 RS22645
gene id: 2494701:FY206_RS22645
uniprot id: A0A5C1C630
names: Similarity
messages: Belongs to the phosphoribulokinase family.

2494701:FY206 RS08160
gene id: 2494701:FY206_RS08160
uniprot id: A0A5C1BY46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell outer membrane
messages: Membrane

2494701:FY206 RS17285
gene id: 2494701:FY206_RS17285
uniprot id: A0A5C1C3N7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane

2494701:FY206 RS07305
gene id: 2494701:FY206_RS07305
uniprot id: A0A5C1BXM4
names: Subcellular Location Annotation
messages: Cytoplasm

2494701:FY206 RS01710
gene id: 2494701:FY206_RS01710
uniprot id: A0A5C1BUG7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family. GltP subfamily.
messages: Catalyzes the proton-dependent transport of glutamate and aspartate.
messages: Cell inner membrane
messages: Membrane

2494701:FY206 RS16480
gene id: 2494701:FY206_RS16480
uniprot id: A0A5C1C2G8
names: Subcellular Location Annotation
messages: Membrane

2494701:FY206 RS01705
gene id: 2494701:FY206_RS01705
uniprot id: A0A5C1BUW0
names: Function
names: PTM
names: Similarity
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. Acs undergoes a two-step reaction. In the first half reaction, Acs combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
messages: Enables the cell to use acetate during aerobic growth to generate energy via the TCA cycle, and biosynthetic compounds via the glyoxylate shunt. Acetylates CheY, the response regulator involved in flagellar movement and chemotaxis.

2494701:FY206 RS16305
gene id: 2494701:FY206_RS16305
uniprot id: A0A5C1C2E3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BexD/CtrA/VexA family.
messages: Cell outer membrane
messages: Membrane

2494701:FY206 RS04585
gene id: 2494701:FY206_RS04585
uniprot id: A0A5C1BW60
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

2494701:FY206 RS24520
gene id: 2494701:FY206_RS24520
uniprot id: A0A5C1C692
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has four main subunits: a(1), b(1), b'(1) and c(9-12).
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

2494701:FY206 RS02605
gene id: 2494701:FY206_RS02605
uniprot id: A0A5C1BUX6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

2494701:FY206 RS22855
gene id: 2494701:FY206_RS22855
uniprot id: A0A5C1C5E4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NfuA family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is presumably bound at the interface of two monomers.
messages: Homodimer.
messages: Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins.

2494701:FY206 RS08925
gene id: 2494701:FY206_RS08925
uniprot id: A0A5C1BYK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2494701:FY206 RS13850
gene id: 2494701:FY206_RS13850
uniprot id: A0A5C1C1X1
names: Similarity
messages: Belongs to the YciI family.

2494701:FY206 RS07950
gene id: 2494701:FY206_RS07950
uniprot id: A0A5C1BY76
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

2494701:FY206 RS04265
gene id: 2494701:FY206_RS04265
uniprot id: A0A5C1BW00
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transpeptidase family. FtsI subfamily.
messages: Catalyzes cross-linking of the peptidoglycan cell wall at the division septum.
messages: Cell inner membrane

2494701:FY206 RS21765
gene id: 2494701:FY206_RS21765
uniprot id: A0A5C1C4Y2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
messages: Cytoplasm
messages: Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.

2494701:FY206 RS18430
gene id: 2494701:FY206_RS18430
uniprot id: A0A5C1C3E7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.

2494701:FY206 RS20375
gene id: 2494701:FY206_RS20375
uniprot id: A0A5C1C416
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LysR transcriptional regulatory family.
messages: Controls the transcription of genes involved in arginine and lysine metabolism.
messages: Homodimer.

2494701:FY206 RS12785
gene id: 2494701:FY206_RS12785
uniprot id: A0A5C1C0B0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the porin LamB (TC 1.B.3) family.
messages: Membrane

2494701:FY206 RS22410
gene id: 2494701:FY206_RS22410
uniprot id: A0A5C1C6B4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

2494701:FY206 RS24860
gene id: 2494701:FY206_RS24860
uniprot id: A0A5C1C725
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.

2494701:FY206 RS04400
gene id: 2494701:FY206_RS04400
uniprot id: A0A5C1BVU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:galactoside symporter (TC 2.A.2) family.
messages: Membrane

2494701:FY206 RS22385
gene id: 2494701:FY206_RS22385
uniprot id: A0A5C1C5W8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

2494701:FY206 RS09400
gene id: 2494701:FY206_RS09400
uniprot id: A0A5C1BYD4
names: Function
names: Similarity
messages: Belongs to the AB hydrolase superfamily. Hydrolase RutD family.
messages: Involved in pyrimidine catabolism. May facilitate the hydrolysis of carbamate, a reaction that can also occur spontaneously.

2494701:FY206 RS15630
gene id: 2494701:FY206_RS15630
uniprot id: A0A5C1C1F2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: Cell inner membrane
messages: FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

2494701:FY206 RS20465
gene id: 2494701:FY206_RS20465
uniprot id: A0A5C1C466
names: Function
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily.
messages: Catalyzes the biosynthesis of agmatine from arginine.

2494701:FY206 RS10915
gene id: 2494701:FY206_RS10915
uniprot id: A0A5C1BZ50
names: Similarity
messages: Belongs to the CFA/CMAS family.

2494701:FY206 RS19640
gene id: 2494701:FY206_RS19640
uniprot id: A0A5C1C562
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

2494701:FY206 RS22905
gene id: 2494701:FY206_RS22905
uniprot id: A0A5C1C6Y4
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
messages: Synthesizes alpha-1,4-glucan chains using ADP-glucose.

2494701:FY206 RS13785
gene id: 2494701:FY206_RS13785
uniprot id: A0A5C1C0N2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the anthranilate synthase component I family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

2494701:FY206 RS04220
gene id: 2494701:FY206_RS04220
uniprot id: A0A5C1BVW4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homotetramer.

2494701:FY206 RS01680
gene id: 2494701:FY206_RS01680
uniprot id: A0A5C1BUS7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2494701:FY206 RS08830
gene id: 2494701:FY206_RS08830
uniprot id: A0A5C1BY69
names: Function
names: Similarity
messages: Belongs to the LpxK family.
messages: Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).

2494701:FY206 RS22960
gene id: 2494701:FY206_RS22960
uniprot id: A0A5C1C5G8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

2494701:FY206 RS15765
gene id: 2494701:FY206_RS15765
uniprot id: A0A5C1C1H5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ApbE family.
messages: Cell inner membrane
messages: Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.
messages: Magnesium. Can also use manganese.

2494701:FY206 RS02300
gene id: 2494701:FY206_RS02300
uniprot id: A0A5C1BV58
names: Function
names: Similarity
messages: Belongs to the LpxC family.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.

2494701:FY206 RS10825
gene id: 2494701:FY206_RS10825
uniprot id: A0A5C1BZD9
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

2494701:FY206 RS01490
gene id: 2494701:FY206_RS01490
uniprot id: A0A5C1BV46
names: Similarity
messages: Belongs to the bacterial solute-binding protein 1 family.

2494701:FY206 RS13415
gene id: 2494701:FY206_RS13415
uniprot id: A0A5C1C197
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the peroxiredoxin family. Tpx subfamily.
messages: Homodimer.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. In this atypical 2-Cys peroxiredoxin, C(R) is present in the same subunit to form an intramolecular disulfide. The disulfide is subsequently reduced by thioredoxin.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

2494701:FY206 RS23535
gene id: 2494701:FY206_RS23535
uniprot id: A0A5C1C5R3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EamA transporter family.
messages: Membrane

2494701:FY206 RS10980
gene id: 2494701:FY206_RS10980
uniprot id: A0A5C1C0K1
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

2494701:FY206 RS22130
gene id: 2494701:FY206_RS22130
uniprot id: A0A5C1C4S9
names: Function
names: Similarity
messages: Belongs to the MreC family.
messages: Involved in formation and maintenance of cell shape.

2494701:FY206 RS12655
gene id: 2494701:FY206_RS12655
uniprot id: A0A5C1C1D8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2494701:FY206 RS14775
gene id: 2494701:FY206_RS14775
uniprot id: A0A5C1C120
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CutC family.
messages: Cytoplasm
messages: Once thought to be involved in copper homeostasis, experiments in E.coli have shown this is not the case.

2494701:FY206 RS00860
gene id: 2494701:FY206_RS00860
uniprot id: A0A5C1BUC1
names: Similarity
messages: Belongs to the FGGY kinase family.

2494701:FY206 RS20525
gene id: 2494701:FY206_RS20525
uniprot id: A0A5C1C475
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Monomer.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

2494701:FY206 RS03830
gene id: 2494701:FY206_RS03830
uniprot id: A0A5C1BVR6
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LplA family.
messages: Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl onto the lipoyl domains of lipoate-dependent enzymes.
messages: Cytoplasm
messages: In the transfer reaction, the free carboxyl group of lipoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.
messages: Monomer.

2494701:FY206 RS22555
gene id: 2494701:FY206_RS22555
uniprot id: A0A5C1C6J0
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

2494701:FY206 RS09465
gene id: 2494701:FY206_RS09465
uniprot id: A0A5C1BYP8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DyP-type peroxidase family. EfeB subfamily.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group non-covalently per subunit.
messages: Homodimer. Part of a ferrous iron transporter composed of EfeU, EfeO and EfeB.
messages: Involved in the recovery of exogenous heme iron. Extracts iron from heme while preserving the protoporphyrin ring intact.
messages: Periplasm

2494701:FY206 RS09005
gene id: 2494701:FY206_RS09005
uniprot id: A0A5C1BYK1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MatP family.
messages: Cytoplasm
messages: Homodimer.
messages: Required for spatial organization of the terminus region of the chromosome (Ter macrodomain) during the cell cycle. Prevents early segregation of duplicated Ter macrodomains during cell division. Binds specifically to matS, which is a 13 bp signature motif repeated within the Ter macrodomain.

2494701:FY206 RS18055
gene id: 2494701:FY206_RS18055
uniprot id: A0A5C1C417
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.

2494701:FY206 RS14735
gene id: 2494701:FY206_RS14735
uniprot id: A0A5C1C1W2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

2494701:FY206 RS07910
gene id: 2494701:FY206_RS07910
uniprot id: A0A5C1BY01
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

2494701:FY206 RS20340
gene id: 2494701:FY206_RS20340
uniprot id: A0A5C1C583
names: Similarity
messages: Belongs to the UPF0149 family.

2494701:FY206 RS08895
gene id: 2494701:FY206_RS08895
uniprot id: A0A5C1BYI7
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

2494701:FY206 RS13345
gene id: 2494701:FY206_RS13345
uniprot id: A0A5C1C0R8
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TtcA family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is chelated by three Cys residues, the fourth Fe has a free coordination site that may bind a sulfur atom transferred from the persulfide of IscS.
messages: Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.
messages: Cytoplasm
messages: Homodimer.
messages: The thiolation reaction likely consists of two steps: a first activation step by ATP to form an adenylated intermediate of the target base of tRNA, and a second nucleophilic substitution step of the sulfur (S) atom supplied by the hydrosulfide attached to the Fe-S cluster.

2494701:FY206 RS23735
gene id: 2494701:FY206_RS23735
uniprot id: A0A5C1C5I3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2494701:FY206 RS11255
gene id: 2494701:FY206_RS11255
uniprot id: A0A5C1BZG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Basic amino acid/polyamine antiporter (APA) (TC 2.A.3.2) family.
messages: Membrane

2494701:FY206 RS02320
gene id: 2494701:FY206_RS02320
uniprot id: A0A5C1BUZ3
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

2494701:FY206 RS10925
gene id: 2494701:FY206_RS10925
uniprot id: A0A5C1C037
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2494701:FY206 RS13515
gene id: 2494701:FY206_RS13515
uniprot id: A0A5C1C0I6
names: Similarity
messages: Belongs to the PspA/IM30 family.

2494701:FY206 RS07325
gene id: 2494701:FY206_RS07325
uniprot id: A0A5C1BYI6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

2494701:FY206 RS09725
gene id: 2494701:FY206_RS09725
uniprot id: A0A5C1BYH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. DHA1 family. MdtG (TC 2.A.1.2.20) subfamily.
messages: Cell membrane
messages: Membrane

2494701:FY206 RS13995
gene id: 2494701:FY206_RS13995
uniprot id: A0A5C1C0N6
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

2494701:FY206 RS23725
gene id: 2494701:FY206_RS23725
uniprot id: A0A5C1C5T7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2494701:FY206 RS06175
gene id: 2494701:FY206_RS06175
uniprot id: A0A5C1BWZ8
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

2494701:FY206 RS10180
gene id: 2494701:FY206_RS10180
uniprot id: A0A5C1BYZ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln), leading to the formation of s(2)U34, the first step of tRNA-mnm(5)s(2)U34 synthesis. Sulfur is provided by IscS, via a sulfur-relay system. Binds ATP and its substrate tRNAs.
messages: Cytoplasm
messages: Interacts with TusE.

2494701:FY206 RS23195
gene id: 2494701:FY206_RS23195
uniprot id: A0A5C1C5G9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm
messages: Required for resistance to DNA-damaging agents.

2494701:FY206 RS05485
gene id: 2494701:FY206_RS05485
uniprot id: A0A5C1BWC6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NiCoT transporter (TC 2.A.52) family. RcnA subfamily.
messages: Cell membrane
messages: Efflux system for nickel and cobalt.
messages: Membrane

2494701:FY206 RS04260
gene id: 2494701:FY206_RS04260
uniprot id: A0A5C1BVT0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsL family.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
messages: Membrane
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

2494701:FY206 RS22080
gene id: 2494701:FY206_RS22080
uniprot id: A0A5C1C4S2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aromatic acid exporter ArAE (TC 2.A.85) family.
messages: Cell membrane
messages: Forms an efflux pump with AaeA. Could function as a metabolic relief valve, allowing to eliminate certain compounds when they accumulate to high levels in the cell.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2494701:FY206 RS19785
gene id: 2494701:FY206_RS19785
uniprot id: A0A5C1C415
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA.
messages: Belongs to the helicase family. UvrD subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding. Interacts with RecA.
messages: The C-terminal domain has nuclease activity and interacts with RecD. It interacts with RecA, facilitating its loading onto ssDNA.
messages: The N-terminal DNA-binding domain is a ssDNA-dependent ATPase and has ATP-dependent 3'-5' helicase function. This domain interacts with RecC.

2494701:FY206 RS11465
gene id: 2494701:FY206_RS11465
uniprot id: A0A5C1BZQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2494701:FY206 RS10220
gene id: 2494701:FY206_RS10220
uniprot id: A0A5C1C076
names: Subcellular Location Annotation
messages: Membrane

2494701:FY206 RS14180
gene id: 2494701:FY206_RS14180
uniprot id: A0A5C1C0T8
names: Similarity
messages: Belongs to the YciI family.

2494701:FY206 RS18045
gene id: 2494701:FY206_RS18045
uniprot id: A0A5C1C2Q5
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

2494701:FY206 RS20585
gene id: 2494701:FY206_RS20585
uniprot id: A0A5C1C426
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nucleoside:H(+) symporter (NHS) (TC 2.A.1.10) family.
messages: Broad-specificity transporter of purine and pyrimidine nucleosides. Transport is driven by a proton motive force.
messages: Cell inner membrane
messages: Membrane

2494701:FY206 RS22445
gene id: 2494701:FY206_RS22445
uniprot id: A0A5C1C4U3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

2494701:FY206 RS24370
gene id: 2494701:FY206_RS24370
uniprot id: A0A5C1C681
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbA subfamily.
messages: Periplasm

2494701:FY206 RS20580
gene id: 2494701:FY206_RS20580
uniprot id: A0A5C1C841
names: Function
names: Similarity
messages: Belongs to the transglycosylase Slt family.
messages: Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and/or cell division.

2494701:FY206 RS04650
gene id: 2494701:FY206_RS04650
uniprot id: A0A5C1BW66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

2494701:FY206 RS03755
gene id: 2494701:FY206_RS03755
uniprot id: A0A5C1BWM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0391 family.
messages: Cell membrane

2494701:FY206 RS23020
gene id: 2494701:FY206_RS23020
uniprot id: A0A5C1C696
names: Similarity
messages: Belongs to the peptidase C40 family.

2494701:FY206 RS17090
gene id: 2494701:FY206_RS17090
uniprot id: A0A5C1C2M4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase Z family. RNase BN subfamily.
messages: Binds 2 Zn(2+) ions.
messages: Homodimer.
messages: Zinc phosphodiesterase, which has both exoribonuclease and endoribonuclease activities.

2494701:FY206 RS22875
gene id: 2494701:FY206_RS22875
uniprot id: A0A5C1C6K4
names: Activity Regulation
names: Function
names: Similarity
names: Subunit
messages: Activated by ATP and maltotriose, which are both required for DNA binding.
messages: Belongs to the MalT family.
messages: Monomer in solution. Oligomerizes to an active state in the presence of the positive effectors ATP and maltotriose.
messages: Positively regulates the transcription of the maltose regulon whose gene products are responsible for uptake and catabolism of malto-oligosaccharides. Specifically binds to the promoter region of its target genes, recognizing a short DNA motif called the MalT box.

2494701:FY206 RS06655
gene id: 2494701:FY206_RS06655
uniprot id: A0A5C1BX11
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

2494701:FY206 RS22515
gene id: 2494701:FY206_RS22515
uniprot id: A0A5C1BUD7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

2494701:FY206 RS06585
gene id: 2494701:FY206_RS06585
uniprot id: A0A5C1BX81
names: Subcellular Location Annotation
messages: Membrane

2494701:FY206 RS08115
gene id: 2494701:FY206_RS08115
uniprot id: A0A5C1BY39
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Dps family.
messages: Cytoplasm
messages: During stationary phase, binds the chromosome non-specifically, forming a highly ordered and stable dps-DNA co-crystal within which chromosomal DNA is condensed and protected from diverse damages. It protects DNA from oxidative damage by sequestering intracellular Fe(2+) ion and storing it in the form of Fe(3+) oxyhydroxide mineral, which can be released after reduction. One hydrogen peroxide oxidizes two Fe(2+) ions, which prevents hydroxyl radical production by the Fenton reaction.
messages: Homododecamer. The 12 subunits form a hollow sphere into which the mineral iron core of up to 500 Fe(3+) can be deposited.

2494701:FY206 RS04485
gene id: 2494701:FY206_RS04485
uniprot id: A0A5C1BWI4
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic AdoMetDC family. Type 2 subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
messages: Heterooctamer of four alpha and four beta chains arranged as a tetramer of alpha/beta heterodimers.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl group blocking the N-terminus of the alpha chain.

2494701:FY206 RS19160
gene id: 2494701:FY206_RS19160
uniprot id: A0A5C1C3B2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

2494701:FY206 RS10775
gene id: 2494701:FY206_RS10775
uniprot id: A0A5C1BZR5
names: Similarity
messages: Belongs to the HesB/IscA family.

2494701:FY206 RS06535
gene id: 2494701:FY206_RS06535
uniprot id: A0A5C1BX63
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

2494701:FY206 RS23350
gene id: 2494701:FY206_RS23350
uniprot id: A0A5C1C6P4
names: Similarity
messages: Belongs to the glycosyl hydrolase 8 (cellulase D) family.

2494701:FY206 RS12135
gene id: 2494701:FY206_RS12135
uniprot id: A0A5C1C0B5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

2494701:FY206 RS19070
gene id: 2494701:FY206_RS19070
uniprot id: A0A5C1C3E9
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

2494701:FY206 RS00640
gene id: 2494701:FY206_RS00640
uniprot id: A0A5C1BTT2
names: Subcellular Location Annotation
messages: Membrane

2494701:FY206 RS23050
gene id: 2494701:FY206_RS23050
uniprot id: A0A5C1C5L0
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Member of a two-component regulatory system.

2494701:FY206 RS08200
gene id: 2494701:FY206_RS08200
uniprot id: A0A5C1BY17
names: Subcellular Location Annotation
messages: Membrane

2494701:FY206 RS06985
gene id: 2494701:FY206_RS06985
uniprot id: A0A5C1BXR6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aldehyde dehydrogenase family.
messages: Binds 2 potassium ions per subunit.
messages: Dimer of dimers.
messages: Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the irreversible oxidation of betaine aldehyde to the corresponding acid.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2494701:FY206 RS08335
gene id: 2494701:FY206_RS08335
uniprot id: A0A5C1BYZ3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArsB family.
messages: Cell membrane
messages: Involved in arsenical resistance. Thought to form the channel of an arsenite pump.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

2494701:FY206 RS14435
gene id: 2494701:FY206_RS14435
uniprot id: A0A5C1C1H2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase Slt family.
messages: Cell outer membrane
messages: Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and/or cell division. Preferentially cleaves at a distance of more than two disaccharide units from the ends of the glycan chain.

2494701:FY206 RS08425
gene id: 2494701:FY206_RS08425
uniprot id: A0A5C1BXZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 3 family.
messages: Periplasm

2494701:FY206 RS15570
gene id: 2494701:FY206_RS15570
uniprot id: A0A5C1C2T5
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

2494701:FY206 RS02570
gene id: 2494701:FY206_RS02570
uniprot id: A0A5C1BUX3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueG family.
messages: Binds 2 [4Fe-4S] clusters per monomer.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

2494701:FY206 RS07805
gene id: 2494701:FY206_RS07805
uniprot id: A0A5C1BXX9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Homodimer.

2494701:FY206 RS02110
gene id: 2494701:FY206_RS02110
uniprot id: A0A5C1BUW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

2494701:FY206 RS24220
gene id: 2494701:FY206_RS24220
uniprot id: A0A5C1C5U7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RTX toxin acyltransferase family.
messages: Cytoplasm
messages: Involved in fatty acylation of protoxin at internal lysine residues, thereby converting it to the active toxin.

2494701:FY206 RS08455
gene id: 2494701:FY206_RS08455
uniprot id: A0A5C1BY62
names: Similarity
messages: Belongs to the UPF0145 family.

2494701:FY206 RS10580
gene id: 2494701:FY206_RS10580
uniprot id: A0A5C1BZ02
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

2494701:FY206 RS24100
gene id: 2494701:FY206_RS24100
uniprot id: A0A5C1C5Q1
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Activates expression of the rhaSR operon in response to L-rhamnose.
messages: Binds DNA as a dimer.
messages: Cytoplasm

2494701:FY206 RS20405
gene id: 2494701:FY206_RS20405
uniprot id: A0A5C1C456
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. Epd subfamily.
messages: Catalyzes the NAD-dependent conversion of D-erythrose 4-phosphate to 4-phosphoerythronate.
messages: Cytoplasm
messages: Homotetramer.

2494701:FY206 RS09740
gene id: 2494701:FY206_RS09740
uniprot id: A0A5C1BYI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0312 family. Type 1 subfamily.
messages: Periplasm

2494701:FY206 RS23095
gene id: 2494701:FY206_RS23095
uniprot id: A0A5C1C6T5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

2494701:FY206 RS20440
gene id: 2494701:FY206_RS20440
uniprot id: A0A5C1C3W4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the periplasmic pilus chaperone family.
messages: Periplasm

2494701:FY206 RS13235
gene id: 2494701:FY206_RS13235
uniprot id: A0A5C1C1M0
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

2494701:FY206 RS23840
gene id: 2494701:FY206_RS23840
uniprot id: A0A5C1C5X2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2494701:FY206 RS00470
gene id: 2494701:FY206_RS00470
uniprot id: A0A5C1BU70
names: Caution
names: Function
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the 2'-O methylation of guanosine at position 18 in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2494701:FY206 RS14580
gene id: 2494701:FY206_RS14580
uniprot id: A0A5C1C1T6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ProQ family.
messages: Cytoplasm
messages: RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities. May regulate ProP activity through an RNA-based, post-transcriptional mechanism.

2494701:FY206 RS15585
gene id: 2494701:FY206_RS15585
uniprot id: A0A5C1C1J9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

2494701:FY206 RS22240
gene id: 2494701:FY206_RS22240
uniprot id: A0A5C1C4U5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

2494701:FY206 RS16180
gene id: 2494701:FY206_RS16180
uniprot id: A0A5C1C7Y6
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

2494701:FY206 RS21545
gene id: 2494701:FY206_RS21545
uniprot id: A0A5C1C4P6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CpxP/Spy family.
messages: Periplasm

2494701:FY206 RS00125
gene id: 2494701:FY206_RS00125
uniprot id: A0A5C1BTW7
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

2494701:FY206 RS15505
gene id: 2494701:FY206_RS15505
uniprot id: A0A5C1C1F8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Cell inner membrane
messages: Membrane
messages: This protein catalyzes the committed step to the synthesis of the acidic phospholipids.

2494701:FY206 RS20600
gene id: 2494701:FY206_RS20600
uniprot id: A0A5C1C473
names: Subcellular Location Annotation
messages: Cytoplasm

2494701:FY206 RS22225
gene id: 2494701:FY206_RS22225
uniprot id: A0A5C1C683
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

2494701:FY206 RS17650
gene id: 2494701:FY206_RS17650
uniprot id: A0A5C1C2S2
names: Subcellular Location Annotation
messages: Membrane

2494701:FY206 RS01350
gene id: 2494701:FY206_RS01350
uniprot id: A0A5C1BU80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PsiE family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

2494701:FY206 RS23935
gene id: 2494701:FY206_RS23935
uniprot id: A0A5C1C7A1
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

2494701:FY206 RS04670
gene id: 2494701:FY206_RS04670
uniprot id: A0A5C1BWE4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

2494701:FY206 RS13900
gene id: 2494701:FY206_RS13900
uniprot id: A0A5C1C1X8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 5 family.
messages: Periplasm

2494701:FY206 RS17810
gene id: 2494701:FY206_RS17810
uniprot id: A0A5C1C2X0
names: Subcellular Location Annotation
messages: Cytoplasm

2494701:FY206 RS14045
gene id: 2494701:FY206_RS14045
uniprot id: A0A5C1C0P5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

2494701:FY206 RS08100
gene id: 2494701:FY206_RS08100
uniprot id: A0A5C1BXZ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

2494701:FY206 RS05050
gene id: 2494701:FY206_RS05050
uniprot id: A0A5C1BWD6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

2494701:FY206 RS16160
gene id: 2494701:FY206_RS16160
uniprot id: A0A5C1C1Q5
names: Subcellular Location Annotation
messages: Membrane

2494701:FY206 RS06545
gene id: 2494701:FY206_RS06545
uniprot id: A0A5C1BX93
names: Function
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.
messages: Catalyzes the phosphorylation of guanosine and inosine to GMP and IMP, respectively.

2494701:FY206 RS00160
gene id: 2494701:FY206_RS00160
uniprot id: A0A5C1BTG8
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Dimer of large and small chains.

2494701:FY206 RS24110
gene id: 2494701:FY206_RS24110
uniprot id: A0A5C1C6S3
names: Function
names: Similarity
messages: Belongs to the rhamnulokinase family.
messages: Involved in the catabolism of L-rhamnose (6-deoxy-L-mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate.

2494701:FY206 RS24080
gene id: 2494701:FY206_RS24080
uniprot id: A0A5C1C759
names: Subcellular Location Annotation
messages: Cell inner membrane

2494701:FY206 RS11735
gene id: 2494701:FY206_RS11735
uniprot id: A0A5C1C0J7
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

2494701:FY206 RS17115
gene id: 2494701:FY206_RS17115
uniprot id: A0A5C1C2A4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

2494701:FY206 RS14785
gene id: 2494701:FY206_RS14785
uniprot id: A0A5C1C1X3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

2494701:FY206 RS20345
gene id: 2494701:FY206_RS20345
uniprot id: A0A5C1C458
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division.
messages: Belongs to the ZapA family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer. Interacts with FtsZ.

2494701:FY206 RS18005
gene id: 2494701:FY206_RS18005
uniprot id: A0A5C1C2Q7
names: Similarity
messages: Belongs to the ArsC family.

2494701:FY206 RS17785
gene id: 2494701:FY206_RS17785
uniprot id: A0A5C1C2Z2
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2494701:FY206 RS24065
gene id: 2494701:FY206_RS24065
uniprot id: A0A5C1C625
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. FieF subfamily.
messages: Cell inner membrane
messages: Divalent metal cation transporter which exports Zn(2+), Cd(2+) and possibly Fe(2+). May be involved in zinc and iron detoxification by efflux.
messages: Homodimer.
messages: Membrane

2494701:FY206 RS05695
gene id: 2494701:FY206_RS05695
uniprot id: A0A5C1BWH0
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

2494701:FY206 RS13020
gene id: 2494701:FY206_RS13020
uniprot id: A0A5C1C1I7
names: Similarity
messages: Belongs to the arylamine N-acetyltransferase family.

2494701:FY206 RS11490
gene id: 2494701:FY206_RS11490
uniprot id: A0A5C1C6K7
names: Subcellular Location Annotation
messages: Membrane

2494701:FY206 RS03870
gene id: 2494701:FY206_RS03870
uniprot id: A0A5C1BVK5
names: Similarity
messages: Belongs to the transglycosylase Slt family.

2494701:FY206 RS16955
gene id: 2494701:FY206_RS16955
uniprot id: A0A5C1C2G7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ApbE family.
messages: Cell inner membrane
messages: Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.
messages: Magnesium. Can also use manganese.

2494701:FY206 RS20935
gene id: 2494701:FY206_RS20935
uniprot id: A0A5C1C5R9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

2494701:FY206 RS01375
gene id: 2494701:FY206_RS01375
uniprot id: A0A5C1BUB1
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the porin LamB (TC 1.B.3) family.
messages: By maltose.
messages: Cell outer membrane
messages: Homotrimer formed of three 18-stranded antiparallel beta-barrels, containing three independent channels.
messages: Involved in the transport of maltose and maltodextrins.
messages: Membrane

2494701:FY206 RS06075
gene id: 2494701:FY206_RS06075
uniprot id: A0A5C1BWY1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the branched chain amino acid transporter family.
messages: Cell inner membrane
messages: Component of the transport system for branched-chain amino acids.
messages: Membrane

2494701:FY206 RS22425
gene id: 2494701:FY206_RS22425
uniprot id: A0A5C1C4X1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

2494701:FY206 RS07245
gene id: 2494701:FY206_RS07245
uniprot id: A0A5C1BXK1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

2494701:FY206 RS04560
gene id: 2494701:FY206_RS04560
uniprot id: A0A5C1BVX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fimbrial export usher family.
messages: Cell outer membrane
messages: Membrane

2494701:FY206 RS23395
gene id: 2494701:FY206_RS23395
uniprot id: A0A5C1C6Z6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TrkH potassium transport family.
messages: Cell inner membrane
messages: Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA.
messages: Membrane

2494701:FY206 RS09030
gene id: 2494701:FY206_RS09030
uniprot id: A0A5C1BYV7
names: Subcellular Location Annotation
messages: Cell inner membrane

2494701:FY206 RS21110
gene id: 2494701:FY206_RS21110
uniprot id: A0A5C1C4L2
names: Cofactor
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
messages: Binds 2 nickel ions per subunit.
messages: Carbamylation allows a single lysine to coordinate two nickel ions.
messages: Carboxylation allows a single lysine to coordinate two nickel ions.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

2494701:FY206 RS07385
gene id: 2494701:FY206_RS07385
uniprot id: A0A5C1BXN9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LptE lipoprotein family.
messages: Component of the lipopolysaccharide transport and assembly complex. Interacts with LptD.
messages: Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane.

2494701:FY206 RS22780
gene id: 2494701:FY206_RS22780
uniprot id: A0A5C1C5F9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IgaA family.
messages: Cell inner membrane
messages: Membrane

2494701:FY206 RS22525
gene id: 2494701:FY206_RS22525
uniprot id: A0A5C1C4Z5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

2494701:FY206 RS00610
gene id: 2494701:FY206_RS00610
uniprot id: A0A5C1BTW8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Cell inner membrane
messages: Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.

2494701:FY206 RS23225
gene id: 2494701:FY206_RS23225
uniprot id: A0A5C1C5P0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycosyl hydrolase 37 family.
messages: Cytoplasm
messages: Hydrolyzes trehalose to glucose. Could be involved, in cells returning to low osmolarity conditions, in the utilization of the accumulated cytoplasmic trehalose, which was synthesized in response to high osmolarity.
messages: Monomer.

2494701:FY206 RS04795
gene id: 2494701:FY206_RS04795
uniprot id: A0A5C1BWA0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

2494701:FY206 RS03645
gene id: 2494701:FY206_RS03645
uniprot id: A0A5C1BVG3
names: Function
names: Similarity
messages: Belongs to the DnaT family.
messages: This protein is required for primosome-dependent normal DNA replication; it is also involved in inducing stable DNA replication during SOS response. It forms, in concert with DnaB protein and other prepriming proteins DnaC, N, N', N'' a prepriming protein complex on the specific site of the template DNA recognized by protein N'.

2494701:FY206 RS16000
gene id: 2494701:FY206_RS16000
uniprot id: A0A5C1C2G5
names: Similarity
messages: Belongs to the peptidase M24B family.

2494701:FY206 RS04130
gene id: 2494701:FY206_RS04130
uniprot id: A0A5C1BWU3
names: Similarity
messages: Belongs to the DNA polymerase type-B family.

2494701:FY206 RS14825
gene id: 2494701:FY206_RS14825
uniprot id: A0A5C1C130
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

2494701:FY206 RS07415
gene id: 2494701:FY206_RS07415
uniprot id: A0A5C1BXP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

2494701:FY206 RS06105
gene id: 2494701:FY206_RS06105
uniprot id: A0A5C1BXU2
names: Function
names: Similarity
messages: Belongs to the AcpH family.
messages: Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP.

2494701:FY206 RS17305
gene id: 2494701:FY206_RS17305
uniprot id: A0A5C1C2X2
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2494701:FY206 RS09940
gene id: 2494701:FY206_RS09940
uniprot id: A0A5C1C038
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

2494701:FY206 RS10130
gene id: 2494701:FY206_RS10130
uniprot id: A0A5C1BZ10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2494701:FY206 RS18450
gene id: 2494701:FY206_RS18450
uniprot id: A0A5C1C2Y7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

2494701:FY206 RS04350
gene id: 2494701:FY206_RS04350
uniprot id: A0A5C1BX00
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ZapD family.
messages: Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity.
messages: Cytoplasm
messages: Interacts with FtsZ.

2494701:FY206 RS06765
gene id: 2494701:FY206_RS06765
uniprot id: A0A5C1BXE8
names: Similarity
messages: Belongs to the bacterial solute-binding protein 1 family.

2494701:FY206 RS13920
gene id: 2494701:FY206_RS13920
uniprot id: A0A5C1C176
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone-like protein H-NS family.
messages: nucleoid

2494701:FY206 RS07980
gene id: 2494701:FY206_RS07980
uniprot id: A0A5C1BXY8
names: Subcellular Location Annotation
messages: Membrane

2494701:FY206 RS14770
gene id: 2494701:FY206_RS14770
uniprot id: A0A5C1C1D7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. CmoB family.
messages: Catalyzes carboxymethyl transfer from carboxy-S-adenosyl-L-methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5-carboxymethoxyuridine (cmo5U) at position 34 in tRNAs.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2494701:FY206 RS06490
gene id: 2494701:FY206_RS06490
uniprot id: A0A5C1BXH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

2494701:FY206 RS19020
gene id: 2494701:FY206_RS19020
uniprot id: A0A5C1C3E2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ElaB/YgaM/YqjD family.
messages: Cell inner membrane
messages: Membrane

2494701:FY206 RS14470
gene id: 2494701:FY206_RS14470
uniprot id: A0A5C1C0V6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaB Na(+)/H(+) (TC 2.A.34) antiporter family.
messages: Cell membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

2494701:FY206 RS19060
gene id: 2494701:FY206_RS19060
uniprot id: A0A5C1C3A0
names: Subcellular Location Annotation
messages: Membrane

2494701:FY206 RS17690
gene id: 2494701:FY206_RS17690
uniprot id: A0A5C1C2K4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.
messages: Membrane

2494701:FY206 RS04430
gene id: 2494701:FY206_RS04430
uniprot id: A0A5C1C7J1
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

2494701:FY206 RS08650
gene id: 2494701:FY206_RS08650
uniprot id: A0A5C1BXZ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

2494701:FY206 RS21445
gene id: 2494701:FY206_RS21445
uniprot id: A0A5C1C4B0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Cell membrane
messages: Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system).
messages: Membrane

2494701:FY206 RS10175
gene id: 2494701:FY206_RS10175
uniprot id: A0A5C1BYT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HflD family.
messages: Cell membrane
messages: Cytoplasm

2494701:FY206 RS08145
gene id: 2494701:FY206_RS08145
uniprot id: A0A5C1BXZ0
names: Subcellular Location Annotation
messages: Membrane

2494701:FY206 RS24205
gene id: 2494701:FY206_RS24205
uniprot id: A0A5C1C648
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the formate dehydrogenase gamma subunit family.
messages: Membrane

2494701:FY206 RS17295
gene id: 2494701:FY206_RS17295
uniprot id: A0A5C1C2R1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 3 family.
messages: Periplasm

2494701:FY206 RS13925
gene id: 2494701:FY206_RS13925
uniprot id: A0A5C1C1X0
names: Similarity
messages: Belongs to the UDPGP type 2 family.

2494701:FY206 RS21920
gene id: 2494701:FY206_RS21920
uniprot id: A0A5C1C6I6
names: Function
names: Similarity
messages: Belongs to the peptidase C56 family.
messages: Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate.

2494701:FY206 RS07365
gene id: 2494701:FY206_RS07365
uniprot id: A0A5C1BXC3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

2494701:FY206 RS20250
gene id: 2494701:FY206_RS20250
uniprot id: A0A5C1C4X6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbC subfamily.
messages: Periplasm
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process.

2494701:FY206 RS15780
gene id: 2494701:FY206_RS15780
uniprot id: A0A5C1C2Y3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I fumarase family.
messages: Catalyzes the reversible hydration of fumarate to (S)-malate.
messages: Homodimer.

2494701:FY206 RS24175
gene id: 2494701:FY206_RS24175
uniprot id: A0A5C1C5W7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the periplasmic pilus chaperone family.
messages: Periplasm

2494701:FY206 RS18270
gene id: 2494701:FY206_RS18270
uniprot id: A0A5C1C386
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Probably plays an important role in intracellular peptide degradation.

2494701:FY206 RS13800
gene id: 2494701:FY206_RS13800
uniprot id: A0A5C1C0J8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

2494701:FY206 RS20420
gene id: 2494701:FY206_RS20420
uniprot id: A0A5C1C4A5
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

2494701:FY206 RS18540
gene id: 2494701:FY206_RS18540
uniprot id: A0A5C1C369
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Metabolite:H+ Symporter (MHS) family (TC 2.A.1.6) family.
messages: Cell inner membrane
messages: Membrane

2494701:FY206 RS18215
gene id: 2494701:FY206_RS18215
uniprot id: A0A5C1C2V3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

2494701:FY206 RS01915
gene id: 2494701:FY206_RS01915
uniprot id: A0A5C1BVB7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NiCoT transporter (TC 2.A.52) family. RcnA subfamily.
messages: Cell membrane
messages: Efflux system for nickel and cobalt.
messages: Membrane

2494701:FY206 RS20680
gene id: 2494701:FY206_RS20680
uniprot id: A0A5C1C5N4
names: Similarity
messages: In the C-terminal section; belongs to the glutathionylspermidine synthase preATP-grasp family.

2494701:FY206 RS20930
gene id: 2494701:FY206_RS20930
uniprot id: A0A5C1C429
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

2494701:FY206 RS15985
gene id: 2494701:FY206_RS15985
uniprot id: A0A5C1C1Y0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the lipid A palmitoyltransferase family.
messages: Cell outer membrane
messages: Homodimer.
messages: Transfers a palmitate residue from the sn-1 position of a phospholipid to the N-linked hydroxymyristate on the proximal unit of lipid A or its precursors.

2494701:FY206 RS02475
gene id: 2494701:FY206_RS02475
uniprot id: A0A5C1BUT3
names: Similarity
messages: Belongs to the EcnA/EcnB lipoprotein family.

2494701:FY206 RS01215
gene id: 2494701:FY206_RS01215
uniprot id: A0A5C1BV00
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endonuclease V family.
messages: Cytoplasm
messages: DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA.

2494701:FY206 RS21820
gene id: 2494701:FY206_RS21820
uniprot id: A0A5C1C4Y9
names: Similarity
messages: Belongs to the ner transcriptional regulatory family.

2494701:FY206 RS15695
gene id: 2494701:FY206_RS15695
uniprot id: A0A5C1C241
names: Similarity
messages: Belongs to the DsrB family.

2494701:FY206 RS18060
gene id: 2494701:FY206_RS18060
uniprot id: A0A5C1C2R5
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

2494701:FY206 RS03815
gene id: 2494701:FY206_RS03815
uniprot id: A0A5C1BVX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the periplasmic pilus chaperone family.
messages: Periplasm

2494701:FY206 RS11745
gene id: 2494701:FY206_RS11745
uniprot id: A0A5C1BZJ0
names: Similarity
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

2494701:FY206 RS11500
gene id: 2494701:FY206_RS11500
uniprot id: A0A5C1C0G0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2494701:FY206 RS08800
gene id: 2494701:FY206_RS08800
uniprot id: A0A5C1BY25
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Monomer.

2494701:FY206 RS14730
gene id: 2494701:FY206_RS14730
uniprot id: A0A5C1C125
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RuvC family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.

2494701:FY206 RS19525
gene id: 2494701:FY206_RS19525
uniprot id: A0A5C1C3P1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).

2494701:FY206 RS22415
gene id: 2494701:FY206_RS22415
uniprot id: A0A5C1C594
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

2494701:FY206 RS03505
gene id: 2494701:FY206_RS03505
uniprot id: A0A5C1BVP0
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

2494701:FY206 RS18160
gene id: 2494701:FY206_RS18160
uniprot id: A0A5C1C431
names: Activity Regulation
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

2494701:FY206 RS14565
gene id: 2494701:FY206_RS14565
uniprot id: A0A5C1C1A0
names: Subcellular Location Annotation
messages: Membrane

2494701:FY206 RS22440
gene id: 2494701:FY206_RS22440
uniprot id: A0A5C1C569
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

2494701:FY206 RS10410
gene id: 2494701:FY206_RS10410
uniprot id: A0A5C1BYW9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in both the arginine and lysine biosynthetic pathways.

2494701:FY206 RS16475
gene id: 2494701:FY206_RS16475
uniprot id: A0A5C1C248
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 32 family.
messages: Cytoplasm
messages: Enables the bacterium to metabolize sucrose as a sole carbon source.

2494701:FY206 RS06230
gene id: 2494701:FY206_RS06230
uniprot id: A0A5C1BXD4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase bacterial subunit 4 family.
messages: Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron.
messages: Heterooctamer of two A chains, two B chains, two C chains and two D chains.
messages: Membrane

2494701:FY206 RS23430
gene id: 2494701:FY206_RS23430
uniprot id: A0A5C1C6G9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RfaH family.
messages: Enhances distal genes transcription elongation in a specialized subset of operons that encode extracytoplasmic components. RfaH is recruited into a multi-component RNA polymerase complex by the ops element, which is a short conserved DNA sequence located downstream of the main promoter of these operons. Once bound, RfaH suppresses pausing and inhibits Rho-dependent and intrinsic termination at a subset of sites. Termination signals are bypassed, which allows complete synthesis of long RNA chains.
messages: Interacts with both the nontemplate DNA and the RNA polymerase (RNAP).

2494701:FY206 RS20325
gene id: 2494701:FY206_RS20325
uniprot id: A0A5C1C3U6
names: Similarity
messages: Belongs to the UbiH/COQ6 family.

2494701:FY206 RS16600
gene id: 2494701:FY206_RS16600
uniprot id: A0A5C1C1Z2
names: Similarity
messages: Belongs to the peptidase S11 family.

2494701:FY206 RS24885
gene id: 2494701:FY206_RS24885
uniprot id: A0A5C1C7W8
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

2494701:FY206 RS14835
gene id: 2494701:FY206_RS14835
uniprot id: A0A5C1C1X9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Cell inner membrane
messages: Membrane

2494701:FY206 RS22185
gene id: 2494701:FY206_RS22185
uniprot id: A0A5C1C4T9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

2494701:FY206 RS24715
gene id: 2494701:FY206_RS24715
uniprot id: A0A5C1C796
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transpeptidase family. FtsI subfamily.
messages: Catalyzes cross-linking of the peptidoglycan cell wall at the division septum.
messages: Cell inner membrane

2494701:FY206 RS13065
gene id: 2494701:FY206_RS13065
uniprot id: A0A5C1C0B2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4-oxalocrotonate tautomerase family. PptA subfamily.
messages: Cytoplasm
messages: Homodimer.

2494701:FY206 RS06200
gene id: 2494701:FY206_RS06200
uniprot id: A0A5C1BWP1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThiI family.
messages: Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2494701:FY206 RS04845
gene id: 2494701:FY206_RS04845
uniprot id: A0A5C1BWA8
names: Similarity
messages: Belongs to the UPF0253 family.

2494701:FY206 RS17400
gene id: 2494701:FY206_RS17400
uniprot id: A0A5C1C2M7
names: Similarity
messages: Belongs to the UPF0115 family.

2494701:FY206 RS16300
gene id: 2494701:FY206_RS16300
uniprot id: A0A5C1C222
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

2494701:FY206 RS16325
gene id: 2494701:FY206_RS16325
uniprot id: A0A5C1C6Q9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uridine kinase family.
messages: Cytoplasm

2494701:FY206 RS02640
gene id: 2494701:FY206_RS02640
uniprot id: A0A5C1BV90
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. RlmB subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the ribose of guanosine 2251 in 23S rRNA.

2494701:FY206 RS02500
gene id: 2494701:FY206_RS02500
uniprot id: A0A5C1BUW2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2494701:FY206 RS04020
gene id: 2494701:FY206_RS04020
uniprot id: A0A5C1BVM7
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

2494701:FY206 RS19815
gene id: 2494701:FY206_RS19815
uniprot id: A0A5C1C6M4
names: Subcellular Location Annotation
messages: Membrane

2494701:FY206 RS09780
gene id: 2494701:FY206_RS09780
uniprot id: A0A5C1BZM3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. DHA1 family. MdtH (TC 2.A.1.2.21) subfamily.
messages: Cell membrane
messages: Membrane

2494701:FY206 RS12105
gene id: 2494701:FY206_RS12105
uniprot id: A0A5C1BZQ5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2494701:FY206 RS25105
gene id: 2494701:FY206_RS25105
uniprot id: A0A5C1C8B4
names: Similarity
messages: Belongs to the GSP E family.

2494701:FY206 RS17160
gene id: 2494701:FY206_RS17160
uniprot id: A0A5C1C2K9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 is composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

2494701:FY206 RS04930
gene id: 2494701:FY206_RS04930
uniprot id: A0A5C1BWB7
names: Subunit
messages: Monomer.

2494701:FY206 RS06575
gene id: 2494701:FY206_RS06575
uniprot id: A0A5C1BWY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

2494701:FY206 RS07905
gene id: 2494701:FY206_RS07905
uniprot id: A0A5C1BY00
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
messages: Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.
messages: Cytoplasm
messages: Homodimer.

2494701:FY206 RS23635
gene id: 2494701:FY206_RS23635
uniprot id: A0A5C1C6Z9
names: Subcellular Location Annotation
messages: Membrane

2494701:FY206 RS03980
gene id: 2494701:FY206_RS03980
uniprot id: A0A5C1BVM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetate uptake transporter (AceTr) (TC 2.A.96) family.
messages: Membrane

2494701:FY206 RS10295
gene id: 2494701:FY206_RS10295
uniprot id: A0A5C1BZI9
names: Similarity
messages: Belongs to the MipA/OmpV family.

2494701:FY206 RS15745
gene id: 2494701:FY206_RS15745
uniprot id: A0A5C1C1R3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Gram-negative porin family.
messages: Cell outer membrane
messages: Homotrimer.
messages: Membrane

2494701:FY206 RS08490
gene id: 2494701:FY206_RS08490
uniprot id: A0A5C1BZ17
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: ATPase component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm. Acts as a molecular motor to provide the energy that is required for assembly of the pseudopilus and the extrusion of substrates generated in the cytoplasm.
messages: Belongs to the GSP E family.
messages: Cell inner membrane

2494701:FY206 RS08975
gene id: 2494701:FY206_RS08975
uniprot id: A0A5C1BYU7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PqiA family.
messages: Component of a transport pathway that contributes to membrane integrity.
messages: Membrane

2494701:FY206 RS17030
gene id: 2494701:FY206_RS17030
uniprot id: A0A5C1C3J7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anaerobic G-3-P dehydrogenase subunit B family.
messages: Composed of a catalytic GlpA/B dimer and of membrane bound GlpC.
messages: Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor.

2494701:FY206 RS07695
gene id: 2494701:FY206_RS07695
uniprot id: A0A5C1BXG4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

2494701:FY206 RS04095
gene id: 2494701:FY206_RS04095
uniprot id: A0A5C1BVP6
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PdxA family.
messages: Binds 1 divalent metal cation per subunit. Can use ions such as Zn(2+), Mg(2+) or Co(2+).
messages: Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L-threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).
messages: Cytoplasm
messages: Homodimer.
messages: The active site is located at the dimer interface.

2494701:FY206 RS16640
gene id: 2494701:FY206_RS16640
uniprot id: A0A5C1C3C2
names: Function
names: Similarity
messages: Belongs to the Dus family. DusC subfamily.
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U16 in tRNAs.

2494701:FY206 RS12965
gene id: 2494701:FY206_RS12965
uniprot id: A0A5C1C1I0
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

2494701:FY206 RS19945
gene id: 2494701:FY206_RS19945
uniprot id: A0A5C1C3R5
names: Subcellular Location Annotation
messages: Membrane

2494701:FY206 RS22360
gene id: 2494701:FY206_RS22360
uniprot id: A0A5C1C6A3
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

2494701:FY206 RS01390
gene id: 2494701:FY206_RS01390
uniprot id: A0A5C1BUQ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family.
messages: Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.
messages: Cell inner membrane

2494701:FY206 RS07220
gene id: 2494701:FY206_RS07220
uniprot id: A0A5C1BX57
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the aldolase class II family. MtnB subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P).

2494701:FY206 RS04730
gene id: 2494701:FY206_RS04730
uniprot id: A0A5C1BWF2
names: Activity Regulation
names: Domain
names: Function
names: Similarity
messages: Belongs to the GlnD family.
messages: Has four distinct domains: an N-terminal nucleotidyltransferase (NT) domain responsible for UTase activity, a central HD domain that encodes UR activity, and two C-terminal ACT domains that seem to have a role in glutamine sensing.
messages: Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism.
messages: Uridylyltransferase (UTase) activity is inhibited by glutamine, while glutamine activates uridylyl-removing (UR) activity.

2494701:FY206 RS01285
gene id: 2494701:FY206_RS01285
uniprot id: A0A5C1BV10
names: Domain
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
messages: Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.

2494701:FY206 RS14495
gene id: 2494701:FY206_RS14495
uniprot id: A0A5C1C6Q1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MinC family.
messages: Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization.
messages: Interacts with MinD and FtsZ.

2494701:FY206 RS04790
gene id: 2494701:FY206_RS04790
uniprot id: A0A5C1BW33
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-(hydroxytetradecanoyl)glucosamine using 3-hydroxytetradecanoyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

2494701:FY206 RS22835
gene id: 2494701:FY206_RS22835
uniprot id: A0A5C1C5D4
names: Function
names: Similarity
messages: Belongs to the FeoC family.
messages: May function as a transcriptional regulator that controls feoABC expression.

2494701:FY206 RS14240
gene id: 2494701:FY206_RS14240
uniprot id: A0A5C1C0S0
names: Similarity
messages: Belongs to the ClpA/ClpB family.

2494701:FY206 RS06025
gene id: 2494701:FY206_RS06025
uniprot id: A0A5C1BWX2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

2494701:FY206 RS21420
gene id: 2494701:FY206_RS21420
uniprot id: A0A5C1C4N4
names: Similarity
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

2494701:FY206 RS19490
gene id: 2494701:FY206_RS19490
uniprot id: A0A5C1C537
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

2494701:FY206 RS14550
gene id: 2494701:FY206_RS14550
uniprot id: A0A5C1C280
names: Function
names: Similarity
messages: Belongs to the Nudix hydrolase family. PCD1 subfamily.
messages: Probably mediates the hydrolysis of some nucleoside diphosphate derivatives.

2494701:FY206 RS19255
gene id: 2494701:FY206_RS19255
uniprot id: A0A5C1C3K0
names: Similarity
messages: Belongs to the peptidase A31 family.

2494701:FY206 RS21465
gene id: 2494701:FY206_RS21465
uniprot id: A0A5C1C5U6
names: Subcellular Location Annotation
messages: Membrane

2494701:FY206 RS09415
gene id: 2494701:FY206_RS09415
uniprot id: A0A5C1BZ46
names: Function
names: Similarity
messages: Belongs to the NtaA/SnaA/DszA monooxygenase family. RutA subfamily.
messages: Catalyzes the pyrimidine ring opening between N-3 and C-4 by an unusual flavin hydroperoxide-catalyzed mechanism, adding oxygen atoms in the process to yield ureidoacrylate peracid, that immediately reacts with FMN forming ureidoacrylate and FMN-N(5)-oxide. The FMN-N(5)-oxide reacts spontaneously with NADH to produce FMN. Requires the flavin reductase RutF to regenerate FMN in vivo.

2494701:FY206 RS21130
gene id: 2494701:FY206_RS21130
uniprot id: A0A5C1C4L3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
messages: Cytoplasm
messages: Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
messages: Homodimer. UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

2494701:FY206 RS08140
gene id: 2494701:FY206_RS08140
uniprot id: A0A5C1BXP5
names: Function
names: Similarity
messages: Belongs to the DtxR/MntR family.
messages: In the presence of manganese, represses expression of mntH and mntS. Up-regulates expression of mntP.

2494701:FY206 RS03745
gene id: 2494701:FY206_RS03745
uniprot id: A0A5C1BVI2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

2494701:FY206 RS23955
gene id: 2494701:FY206_RS23955
uniprot id: A0A5C1C5Z9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

2494701:FY206 RS10320
gene id: 2494701:FY206_RS10320
uniprot id: A0A5C1BZV5
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family.

2494701:FY206 RS07645
gene id: 2494701:FY206_RS07645
uniprot id: A0A5C1BXQ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LamB/PxpA family.
messages: Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
messages: Forms a complex composed of PxpA, PxpB and PxpC.

2494701:FY206 RS08505
gene id: 2494701:FY206_RS08505
uniprot id: A0A5C1BY55
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

2494701:FY206 RS10115
gene id: 2494701:FY206_RS10115
uniprot id: A0A5C1C059
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

2494701:FY206 RS09980
gene id: 2494701:FY206_RS09980
uniprot id: A0A5C1BYP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

2494701:FY206 RS14870
gene id: 2494701:FY206_RS14870
uniprot id: A0A5C1C1F1
names: Subcellular Location Annotation
messages: Membrane

2494701:FY206 RS23085
gene id: 2494701:FY206_RS23085
uniprot id: A0A5C1C581
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M23B family.
messages: Membrane

2494701:FY206 RS24340
gene id: 2494701:FY206_RS24340
uniprot id: A0A5C1C7I3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Monomer.

2494701:FY206 RS10665
gene id: 2494701:FY206_RS10665
uniprot id: A0A5C1BZC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:galactoside symporter (TC 2.A.2) family.
messages: Membrane

2494701:FY206 RS03875
gene id: 2494701:FY206_RS03875
uniprot id: A0A5C1BVJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TrpR family.
messages: Cytoplasm
messages: Homodimer.
messages: This protein is an aporepressor. When complexed with L-tryptophan it binds the operator region of the trp operon (5'-ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region.

2494701:FY206 RS22200
gene id: 2494701:FY206_RS22200
uniprot id: A0A5C1C5U2
names: Function
names: Similarity
names: Subunit
messages: Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters.
messages: Belongs to the transcriptional regulatory Fis family.
messages: Homodimer.

2494701:FY206 RS07195
gene id: 2494701:FY206_RS07195
uniprot id: A0A5C1BXJ3
names: Similarity
messages: Belongs to the AHA1 family.

2494701:FY206 RS07890
gene id: 2494701:FY206_RS07890
uniprot id: A0A5C1BXU0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urocanase family.
messages: Binds 1 NAD(+) per subunit.
messages: Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
messages: Cytoplasm

2494701:FY206 RS17125
gene id: 2494701:FY206_RS17125
uniprot id: A0A5C1C321
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: NDH-1 is composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

2494701:FY206 RS00015
gene id: 2494701:FY206_RS00015
uniprot id: A0A5C1BTJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

2494701:FY206 RS13080
gene id: 2494701:FY206_RS13080
uniprot id: A0A5C1C046
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

2494701:FY206 RS22300
gene id: 2494701:FY206_RS22300
uniprot id: A0A5C1C4Q9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family. TsaC subfamily.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate.

2494701:FY206 RS18325
gene id: 2494701:FY206_RS18325
uniprot id: A0A5C1C334
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NiCoT transporter (TC 2.A.52) family. RcnA subfamily.
messages: Cell membrane
messages: Efflux system for nickel and cobalt.
messages: Membrane

2494701:FY206 RS09935
gene id: 2494701:FY206_RS09935
uniprot id: A0A5C1BZP7
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

2494701:FY206 RS03065
gene id: 2494701:FY206_RS03065
uniprot id: A0A5C1BV94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

2494701:FY206 RS00460
gene id: 2494701:FY206_RS00460
uniprot id: A0A5C1BU01
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate:Na(+) symporter (ESS) (TC 2.A.27) family.
messages: Catalyzes the sodium-dependent transport of glutamate.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2494701:FY206 RS20535
gene id: 2494701:FY206_RS20535
uniprot id: A0A5C1C4C4
names: Similarity
messages: Belongs to the UPF0235 family.

2494701:FY206 RS21525
gene id: 2494701:FY206_RS21525
uniprot id: A0A5C1C4Q1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2494701:FY206 RS07350
gene id: 2494701:FY206_RS07350
uniprot id: A0A5C1BXY2
names: Function
names: Similarity
messages: Belongs to the RlpA family.
messages: Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.

2494701:FY206 RS08355
gene id: 2494701:FY206_RS08355
uniprot id: A0A5C1BY44
names: Subunit
messages: Monomer.

2494701:FY206 RS09925
gene id: 2494701:FY206_RS09925
uniprot id: A0A5C1BYN3
names: Similarity
messages: Belongs to the fabD family.

2494701:FY206 RS04825
gene id: 2494701:FY206_RS04825
uniprot id: A0A5C1BX89
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-I family.

2494701:FY206 RS04450
gene id: 2494701:FY206_RS04450
uniprot id: A0A5C1BVV4
names: Cofactor
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Binds 1 [4Fe-4S] cluster per subunit.

2494701:FY206 RS19155
gene id: 2494701:FY206_RS19155
uniprot id: A0A5C1C3I4
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

2494701:FY206 RS00770
gene id: 2494701:FY206_RS00770
uniprot id: A0A5C1BTV3
names: Similarity
messages: Belongs to the mannitol dehydrogenase family.

2494701:FY206 RS08955
gene id: 2494701:FY206_RS08955
uniprot id: A0A5C1BYJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ZapC family.
messages: Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ.
messages: Cytoplasm
messages: Interacts directly with FtsZ.

2494701:FY206 RS10745
gene id: 2494701:FY206_RS10745
uniprot id: A0A5C1BZ25
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

2494701:FY206 RS20700
gene id: 2494701:FY206_RS20700
uniprot id: A0A5C1C438
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Cell inner membrane
messages: Membrane

2494701:FY206 RS11120
gene id: 2494701:FY206_RS11120
uniprot id: A0A5C1BZS2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of adenosine and 2-deoxyadenosine.

2494701:FY206 RS04665
gene id: 2494701:FY206_RS04665
uniprot id: A0A5C1BX61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

2494701:FY206 RS13410
gene id: 2494701:FY206_RS13410
uniprot id: A0A5C1C0G6
names: Cofactor
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.

2494701:FY206 RS10835
gene id: 2494701:FY206_RS10835
uniprot id: A0A5C1BZE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2494701:FY206 RS11330
gene id: 2494701:FY206_RS11330
uniprot id: A0A5C1BZE0
names: Similarity
messages: Belongs to the peptidase S24 family.

2494701:FY206 RS19920
gene id: 2494701:FY206_RS19920
uniprot id: A0A5C1C5B3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2494701:FY206 RS09555
gene id: 2494701:FY206_RS09555
uniprot id: A0A5C1BYY6
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the PHP family.
messages: Binds 3 Zn(2+) ions per subunit.
messages: Homotrimer.

2494701:FY206 RS18455
gene id: 2494701:FY206_RS18455
uniprot id: A0A5C1C4N3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

2494701:FY206 RS11265
gene id: 2494701:FY206_RS11265
uniprot id: A0A5C1BZZ1
names: Function
names: Similarity
messages: Belongs to the AlaDH/PNT family.
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

2494701:FY206 RS00250
gene id: 2494701:FY206_RS00250
uniprot id: A0A5C1BTV1
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane.

2494701:FY206 RS13145
gene id: 2494701:FY206_RS13145
uniprot id: A0A5C1C0J6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

2494701:FY206 RS17175
gene id: 2494701:FY206_RS17175
uniprot id: A0A5C1C329
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 5DNU family.
messages: Catalyzes the strictly specific dephosphorylation of 2'-deoxyribonucleoside 5'-monophosphates.
messages: Cytoplasm
messages: Homodimer.

2494701:FY206 RS17410
gene id: 2494701:FY206_RS17410
uniprot id: A0A5C1C3Q7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the formation of a hydroxyacyl-CoA by addition of water on enoyl-CoA. Also exhibits 3-hydroxyacyl-CoA epimerase and 3-hydroxyacyl-CoA dehydrogenase activities.
messages: Cytoplasm
messages: Heterotetramer of two alpha chains (FadJ) and two beta chains (FadI).
messages: In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.
messages: In the central section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

2494701:FY206 RS16045
gene id: 2494701:FY206_RS16045
uniprot id: A0A5C1C1Z1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA gyrase inhibitor family.
messages: Cytoplasm
messages: Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell.
messages: Interacts with DNA gyrase.

2494701:FY206 RS02850
gene id: 2494701:FY206_RS02850
uniprot id: A0A5C1BV23
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

2494701:FY206 RS04855
gene id: 2494701:FY206_RS04855
uniprot id: A0A5C1C6F4
names: Similarity
messages: Belongs to the prokaryotic/mitochondrial release factor family.

2494701:FY206 RS13005
gene id: 2494701:FY206_RS13005
uniprot id: A0A5C1C047
names: Subcellular Location Annotation
messages: Membrane

2494701:FY206 RS02550
gene id: 2494701:FY206_RS02550
uniprot id: A0A5C1BV96
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-to-5' exoribonuclease specific for small oligoribonucleotides.
messages: Belongs to the oligoribonuclease family.
messages: Cytoplasm

2494701:FY206 RS00075
gene id: 2494701:FY206_RS00075
uniprot id: A0A5C1BTV6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with aggregated proteins, together with IbpA, to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress. Aggregated proteins bound to the IbpAB complex are more efficiently refolded and reactivated by the ATP-dependent chaperone systems ClpB and DnaK/DnaJ/GrpE. Its activity is ATP-independent.
messages: Belongs to the small heat shock protein (HSP20) family.
messages: Cytoplasm
messages: Homodimer. Forms homomultimers of about 100-150 subunits at optimal growth temperatures. Conformation changes to oligomers at high temperatures or high ionic concentrations. The decrease in size of the multimers is accompanied by an increase in chaperone activity.
messages: The N- and C-terminal flexible termini are involved in oligomerization and in the binding of non-native substrate proteins, and are essential for chaperone activity.

2494701:FY206 RS15995
gene id: 2494701:FY206_RS15995
uniprot id: A0A5C1C1N2
names: Function
names: Similarity
messages: Belongs to the AMP nucleosidase family.
messages: Catalyzes the hydrolysis of the N-glycosidic bond of AMP to form adenine and ribose 5-phosphate. Involved in regulation of AMP concentrations.

2494701:FY206 RS10660
gene id: 2494701:FY206_RS10660
uniprot id: A0A5C1BZQ2
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

2494701:FY206 RS11355
gene id: 2494701:FY206_RS11355
uniprot id: A0A5C1BZI6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family. MdtJ subfamily.
messages: Catalyzes the excretion of spermidine.
messages: Cell inner membrane
messages: Cell membrane
messages: Forms a complex with MdtI.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

2494701:FY206 RS14575
gene id: 2494701:FY206_RS14575
uniprot id: A0A5C1C104
names: Similarity
messages: Belongs to the peptidase S41A family.

2494701:FY206 RS04310
gene id: 2494701:FY206_RS04310
uniprot id: A0A5C1BVT9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsQ/DivIB family. FtsQ subfamily.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly.
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

2494701:FY206 RS02520
gene id: 2494701:FY206_RS02520
uniprot id: A0A5C1BVK6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Part of an enzyme complex containing four subunits: a flavoprotein (FrdA), an iron-sulfur protein (FrdB), and two hydrophobic anchor proteins (FrdC and FrdD).

2494701:FY206 RS06115
gene id: 2494701:FY206_RS06115
uniprot id: A0A5C1BWP6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

2494701:FY206 RS05045
gene id: 2494701:FY206_RS05045
uniprot id: A0A5C1BW74
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NqrA family.
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

2494701:FY206 RS00170
gene id: 2494701:FY206_RS00170
uniprot id: A0A5C1BTN0
names: Subcellular Location Annotation
messages: Membrane

2494701:FY206 RS23475
gene id: 2494701:FY206_RS23475
uniprot id: A0A5C1C5S5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PNP/UDP phosphorylase family.
messages: Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis.
messages: Cytoplasm

2494701:FY206 RS12875
gene id: 2494701:FY206_RS12875
uniprot id: A0A5C1C0I1
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.
messages: Homotetramer.

2494701:FY206 RS06040
gene id: 2494701:FY206_RS06040
uniprot id: A0A5C1BWZ9
names: Function
names: Similarity
messages: Belongs to the nucleoside phosphorylase PpnP family.
messages: Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions.

2494701:FY206 RS00795
gene id: 2494701:FY206_RS00795
uniprot id: A0A5C1BTX2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SelA family.
messages: Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers. Binds only one seryl-tRNA(Sec) per dimer.

2494701:FY206 RS06780
gene id: 2494701:FY206_RS06780
uniprot id: A0A5C1BWZ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

2494701:FY206 RS11605
gene id: 2494701:FY206_RS11605
uniprot id: A0A5C1BZS4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0060 family.
messages: Cell membrane

2494701:FY206 RS16285
gene id: 2494701:FY206_RS16285
uniprot id: A0A5C1C365
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

2494701:FY206 RS09755
gene id: 2494701:FY206_RS09755
uniprot id: A0A5C1BZ98
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MSOX/MTOX family. MTOX subfamily.
messages: Binds 1 FAD per subunit.
messages: Catalyzes the oxidative demethylation of N-methyl-L-tryptophan.
messages: Monomer.

2494701:FY206 RS21750
gene id: 2494701:FY206_RS21750
uniprot id: A0A5C1C4Y7
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

2494701:FY206 RS19095
gene id: 2494701:FY206_RS19095
uniprot id: A0A5C1C399
names: Similarity
messages: Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily.

2494701:FY206 RS14570
gene id: 2494701:FY206_RS14570
uniprot id: A0A5C1C0Y4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

2494701:FY206 RS04175
gene id: 2494701:FY206_RS04175
uniprot id: A0A5C1BVR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 1 family.
messages: Periplasm

2494701:FY206 RS00800
gene id: 2494701:FY206_RS00800
uniprot id: A0A5C1BU23
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Translation factor necessary for the incorporation of selenocysteine into proteins. It probably replaces EF-Tu for the insertion of selenocysteine directed by the UGA codon. SelB binds GTP and GDP.

2494701:FY206 RS16105
gene id: 2494701:FY206_RS16105
uniprot id: A0A5C1C203
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

2494701:FY206 RS08380
gene id: 2494701:FY206_RS08380
uniprot id: A0A5C1BXR0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein PotD/PotF family.
messages: Periplasm
messages: Required for the activity of the bacterial periplasmic transport system of putrescine.

2494701:FY206 RS04970
gene id: 2494701:FY206_RS04970
uniprot id: A0A5C1BWJ0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

2494701:FY206 RS12385
gene id: 2494701:FY206_RS12385
uniprot id: A0A5C1C198
names: Similarity
messages: Belongs to the four-carbon acid sugar kinase family.

2494701:FY206 RS24005
gene id: 2494701:FY206_RS24005
uniprot id: A0A5C1C611
names: Activity Regulation
names: Function
names: Similarity
names: Subunit
messages: Activity of this regulatory enzyme is affected by several metabolites. Allosterically and non-competitively inhibited by fructose 1,6-bisphosphate (FBP) and unphosphorylated phosphocarrier protein EIIA-Glc (III-Glc), an integral component of the bacterial phosphotransferase (PTS) system.
messages: Belongs to the FGGY kinase family.
messages: Homotetramer and homodimer (in equilibrium). Heterodimer with EIIA-Glc. Binds 1 zinc ion per glycerol kinase EIIA-Glc dimer. The zinc ion is important for dimerization.
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.

2494701:FY206 RS07785
gene id: 2494701:FY206_RS07785
uniprot id: A0A5C1BXS5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family.
messages: Membrane
messages: Required for nicotinamide riboside transport across the inner membrane.

2494701:FY206 RS18475
gene id: 2494701:FY206_RS18475
uniprot id: A0A5C1C361
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

2494701:FY206 RS02730
gene id: 2494701:FY206_RS02730
uniprot id: A0A5C1BV57
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PriB family.
messages: Binds single-stranded DNA at the primosome assembly site (PAS).
messages: Component of the preprimosomal complex composed of PriA, PriB, PriC, DnaB and DnaT. Upon transient interaction with DnaG it forms the primosome.

2494701:FY206 RS09890
gene id: 2494701:FY206_RS09890
uniprot id: A0A5C1BYN4
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

2494701:FY206 RS23810
gene id: 2494701:FY206_RS23810
uniprot id: A0A5C1C6M6
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

2494701:FY206 RS07895
gene id: 2494701:FY206_RS07895
uniprot id: A0A5C1BXV8
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAL/histidase family.
messages: Contains an active site 4-methylidene-imidazol-5-one (MIO), which is formed autocatalytically by cyclization and dehydration of residues Ala-Ser-Gly.
messages: Cytoplasm

2494701:FY206 RS21670
gene id: 2494701:FY206_RS21670
uniprot id: A0A5C1C4E6
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

2494701:FY206 RS18275
gene id: 2494701:FY206_RS18275
uniprot id: A0A5C1C324
names: Function
names: Similarity
messages: Belongs to the IscX family.
messages: May function as iron donor in the assembly of iron-sulfur clusters.

2494701:FY206 RS03070
gene id: 2494701:FY206_RS03070
uniprot id: A0A5C1BV65
names: Similarity
messages: Belongs to the carbamate kinase family.

2494701:FY206 RS07955
gene id: 2494701:FY206_RS07955
uniprot id: A0A5C1BY10
names: Function
names: Similarity
messages: Belongs to the MoaB/Mog family.
messages: May be involved in the biosynthesis of molybdopterin.

2494701:FY206 RS10355
gene id: 2494701:FY206_RS10355
uniprot id: A0A5C1BZB6
names: Function
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
messages: Catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate and ammonia.

2494701:FY206 RS20800
gene id: 2494701:FY206_RS20800
uniprot id: A0A5C1C4C3
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.

2494701:FY206 RS22560
gene id: 2494701:FY206_RS22560
uniprot id: A0A5C1C6Q0
names: Similarity
messages: Belongs to the SlyX family.

2494701:FY206 RS03475
gene id: 2494701:FY206_RS03475
uniprot id: A0A5C1BWH8
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

2494701:FY206 RS00440
gene id: 2494701:FY206_RS00440
uniprot id: A0A5C1BUZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:galactoside symporter (TC 2.A.2) family.
messages: Membrane

2494701:FY206 RS12490
gene id: 2494701:FY206_RS12490
uniprot id: A0A5C1C1B5
names: Subunit
messages: Homodimer.

2494701:FY206 RS17255
gene id: 2494701:FY206_RS17255
uniprot id: A0A5C1C3N3
names: Similarity
messages: Belongs to the GST superfamily.

2494701:FY206 RS09305
gene id: 2494701:FY206_RS09305
uniprot id: A0A5C1BYL7
names: Similarity
messages: Belongs to the glycosyl hydrolase 53 family.

2494701:FY206 RS01675
gene id: 2494701:FY206_RS01675
uniprot id: A0A5C1BVM5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

2494701:FY206 RS18290
gene id: 2494701:FY206_RS18290
uniprot id: A0A5C1C354
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HscB family.
messages: Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA.
messages: Interacts with HscA and stimulates its ATPase activity. Interacts with IscU.

2494701:FY206 RS20880
gene id: 2494701:FY206_RS20880
uniprot id: A0A5C1C5R1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsP family.
messages: Cell division protein that is required for growth during stress conditions. May be involved in protecting or stabilizing the divisomal assembly under conditions of stress.
messages: Periplasm

2494701:FY206 RS17070
gene id: 2494701:FY206_RS17070
uniprot id: A0A5C1C285
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TPP enzyme family. MenD subfamily.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
messages: Homodimer.

2494701:FY206 RS13130
gene id: 2494701:FY206_RS13130
uniprot id: A0A5C1C061
names: Subcellular Location Annotation
messages: Membrane

2494701:FY206 RS08265
gene id: 2494701:FY206_RS08265
uniprot id: A0A5C1BY66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

2494701:FY206 RS02690
gene id: 2494701:FY206_RS02690
uniprot id: A0A5C1BVA0
names: Subcellular Location Annotation
messages: Membrane

2494701:FY206 RS03985
gene id: 2494701:FY206_RS03985
uniprot id: A0A5C1BVM3
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

2494701:FY206 RS22340
gene id: 2494701:FY206_RS22340
uniprot id: A0A5C1C552
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell inner membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

2494701:FY206 RS11380
gene id: 2494701:FY206_RS11380
uniprot id: A0A5C1BZW9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M32 family.
messages: Binds 1 zinc ion per subunit.
messages: Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues.

2494701:FY206 RS13890
gene id: 2494701:FY206_RS13890
uniprot id: A0A5C1C0P8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

2494701:FY206 RS22925
gene id: 2494701:FY206_RS22925
uniprot id: A0A5C1C6R1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2494701:FY206 RS16435
gene id: 2494701:FY206_RS16435
uniprot id: A0A5C1C1W6
names: Function
names: Similarity
messages: Belongs to the Thz kinase family.
messages: Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).

2494701:FY206 RS24775
gene id: 2494701:FY206_RS24775
uniprot id: A0A5C1C7S9
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

2494701:FY206 RS07250
gene id: 2494701:FY206_RS07250
uniprot id: A0A5C1BXW2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.
messages: Serves to protect the cell against DNA damage by alkyl hydroperoxides. It can use either NADH or NADPH as electron donor for direct reduction of redox dyes or of alkyl hydroperoxides when combined with the AhpC protein.

2494701:FY206 RS13790
gene id: 2494701:FY206_RS13790
uniprot id: A0A5C1C1F4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2494701:FY206 RS23400
gene id: 2494701:FY206_RS23400
uniprot id: A0A5C1C5R4
names: Similarity
messages: Belongs to the IMPACT family.

2494701:FY206 RS18405
gene id: 2494701:FY206_RS18405
uniprot id: A0A5C1C4M4
names: Subcellular Location Annotation
messages: Membrane

2494701:FY206 RS08270
gene id: 2494701:FY206_RS08270
uniprot id: A0A5C1BY71
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
messages: Cytoplasm

2494701:FY206 RS18850
gene id: 2494701:FY206_RS18850
uniprot id: A0A5C1C3G6
names: Subcellular Location Annotation
messages: Membrane

2494701:FY206 RS01235
gene id: 2494701:FY206_RS01235
uniprot id: A0A5C1BU60
names: Similarity
messages: Belongs to the GARS family.

2494701:FY206 RS17980
gene id: 2494701:FY206_RS17980
uniprot id: A0A5C1C2Z5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

2494701:FY206 RS20875
gene id: 2494701:FY206_RS20875
uniprot id: A0A5C1C422
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TrkH potassium transport family.
messages: Cell inner membrane
messages: Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA.
messages: Membrane

2494701:FY206 RS17895
gene id: 2494701:FY206_RS17895
uniprot id: A0A5C1C310
names: Similarity
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the malic enzymes family.

2494701:FY206 RS02145
gene id: 2494701:FY206_RS02145
uniprot id: A0A5C1BVW2
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

2494701:FY206 RS03810
gene id: 2494701:FY206_RS03810
uniprot id: A0A5C1BWN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fimbrial export usher family.
messages: Cell outer membrane
messages: Membrane

2494701:FY206 RS10125
gene id: 2494701:FY206_RS10125
uniprot id: A0A5C1BYY8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein PotD/PotF family.
messages: Periplasm
messages: Required for the activity of the bacterial periplasmic transport system of putrescine.

2494701:FY206 RS23595
gene id: 2494701:FY206_RS23595
uniprot id: A0A5C1C5G3
names: Function
names: Similarity
messages: Belongs to the uroporphyrinogen-III synthase family.
messages: Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.

2494701:FY206 RS19575
gene id: 2494701:FY206_RS19575
uniprot id: A0A5C1C3Q0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Alpha(8)-beta(8). The alpha component is a flavoprotein, the beta component is a hemoprotein.
messages: Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Binds 1 siroheme per subunit.
messages: Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate.

2494701:FY206 RS23010
gene id: 2494701:FY206_RS23010
uniprot id: A0A5C1C5K2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2494701:FY206 RS22155
gene id: 2494701:FY206_RS22155
uniprot id: A0A5C1C4N7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MsrQ family.
messages: Binds 1 FMN per subunit.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Cell membrane
messages: Heterodimer of a catalytic subunit (MsrP) and a heme-binding subunit (MsrQ).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain.

2494701:FY206 RS14965
gene id: 2494701:FY206_RS14965
uniprot id: A0A5C1C1C8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid/polyamine transporter 2 family. Mtr/TnaB/TyrP permease subfamily.
messages: Cell inner membrane
messages: Involved in transporting aromatic amino acids across the cytoplasmic membrane.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

2494701:FY206 RS24040
gene id: 2494701:FY206_RS24040
uniprot id: A0A5C1C605
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

2494701:FY206 RS21610
gene id: 2494701:FY206_RS21610
uniprot id: A0A5C1C4Q7
names: Similarity
messages: Belongs to the UPF0102 family.

2494701:FY206 RS01325
gene id: 2494701:FY206_RS01325
uniprot id: A0A5C1BU99
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

2494701:FY206 RS14065
gene id: 2494701:FY206_RS14065
uniprot id: A0A5C1C207
names: Subcellular Location Annotation
messages: Membrane

2494701:FY206 RS19895
gene id: 2494701:FY206_RS19895
uniprot id: A0A5C1C427
names: Subcellular Location Annotation
messages: Membrane

2494701:FY206 RS20235
gene id: 2494701:FY206_RS20235
uniprot id: A0A5C1C411
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

2494701:FY206 RS00865
gene id: 2494701:FY206_RS00865
uniprot id: A0A5C1BU24
names: Subcellular Location Annotation
messages: Membrane

2494701:FY206 RS02010
gene id: 2494701:FY206_RS02010
uniprot id: A0A5C1BUP2
names: Similarity
messages: Belongs to the UPF0401 family.

2494701:FY206 RS21640
gene id: 2494701:FY206_RS21640
uniprot id: A0A5C1C4R8
names: Similarity
messages: Belongs to the UPF0306 family.

2494701:FY206 RS01640
gene id: 2494701:FY206_RS01640
uniprot id: A0A5C1BUG3
names: Function
names: Subunit
messages: Homotetramer.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

2494701:FY206 RS00950
gene id: 2494701:FY206_RS00950
uniprot id: A0A5C1BU07
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acyltransferase 3 family.
messages: Cell inner membrane
messages: Responsible for the incorporation of O-acetyl groups into the enterobacterial common antigen (ECA) trisaccharide repeat units.

2494701:FY206 RS02580
gene id: 2494701:FY206_RS02580
uniprot id: A0A5C1BV29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

2494701:FY206 RS15755
gene id: 2494701:FY206_RS15755
uniprot id: A0A5C1C2X1
names: Subcellular Location Annotation
messages: Membrane

2494701:FY206 RS10400
gene id: 2494701:FY206_RS10400
uniprot id: A0A5C1BZ88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Membrane

2494701:FY206 RS08845
gene id: 2494701:FY206_RS08845
uniprot id: A0A5C1BYH5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
messages: Belongs to the KdsB family.
messages: Cytoplasm

2494701:FY206 RS23065
gene id: 2494701:FY206_RS23065
uniprot id: A0A5C1C5L1
names: Similarity
messages: Belongs to the CopC family.

2494701:FY206 RS12845
gene id: 2494701:FY206_RS12845
uniprot id: A0A5C1C6P5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2494701:FY206 RS03200
gene id: 2494701:FY206_RS03200
uniprot id: A0A5C1BWD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YtcA family.
messages: Membrane

2494701:FY206 RS02470
gene id: 2494701:FY206_RS02470
uniprot id: A0A5C1C6C7
names: Similarity
messages: Belongs to the EcnA/EcnB lipoprotein family.

2494701:FY206 RS04235
gene id: 2494701:FY206_RS04235
uniprot id: A0A5C1BVR5
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

2494701:FY206 RS18580
gene id: 2494701:FY206_RS18580
uniprot id: A0A5C1C307
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamD family.
messages: Cell outer membrane
messages: Part of the Bam complex, which is composed of the outer membrane protein BamA, and four lipoproteins BamB, BamC, BamD and BamE.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. Constitutes, with BamA, the core component of the assembly machinery.

2494701:FY206 RS07720
gene id: 2494701:FY206_RS07720
uniprot id: A0A5C1BXW7
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

2494701:FY206 RS23465
gene id: 2494701:FY206_RS23465
uniprot id: A0A5C1C5S3
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).

2494701:FY206 RS24055
gene id: 2494701:FY206_RS24055
uniprot id: A0A5C1C621
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic sulfate-binding protein family.
messages: Periplasm

2494701:FY206 RS19950
gene id: 2494701:FY206_RS19950
uniprot id: A0A5C1C434
names: Subcellular Location Annotation
messages: Cytoplasm

2494701:FY206 RS00845
gene id: 2494701:FY206_RS00845
uniprot id: A0A5C1BTY4
names: Similarity
messages: Belongs to the aldolase class II family. AraD/FucA subfamily.

2494701:FY206 RS18680
gene id: 2494701:FY206_RS18680
uniprot id: A0A5C1C3B5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

2494701:FY206 RS11615
gene id: 2494701:FY206_RS11615
uniprot id: A0A5C1BZI5
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

2494701:FY206 RS24200
gene id: 2494701:FY206_RS24200
uniprot id: A0A5C1C5R8
names: Cofactor
names: Function
names: Subcellular Location Annotation
messages: Binds 4 [4Fe-4S] clusters per subunit.
messages: Membrane
messages: The beta chain is an electron transfer unit containing 4 cysteine clusters involved in the formation of iron-sulfur centers.

2494701:FY206 RS18410
gene id: 2494701:FY206_RS18410
uniprot id: A0A5C1C478
names: Function
names: Induction
names: Miscellaneous
names: Similarity
names: Subunit
messages: A lyase-type mechanism (elimination/hydration) is suggested for the cleavage of the lactyl ether bond of MurNAc 6-phosphate, with the formation of an alpha,beta-unsaturated aldehyde intermediate with (E)-stereochemistry, followed by the syn addition of water to give product.
messages: Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.
messages: Homodimer.
messages: Induced by MurNAc 6-phosphate that releases the repressor MurR from the DNA. Repressed by MurR in the absence of MurNAc 6-phosphate.
messages: Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate. Together with AnmK, is also required for the utilization of anhydro-N-acetylmuramic acid (anhMurNAc) either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.

2494701:FY206 RS04720
gene id: 2494701:FY206_RS04720
uniprot id: A0A5C1BW01
names: Similarity
messages: Belongs to the UPF0325 family.

2494701:FY206 RS15510
gene id: 2494701:FY206_RS15510
uniprot id: A0A5C1C290
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

2494701:FY206 RS09930
gene id: 2494701:FY206_RS09930
uniprot id: A0A5C1BYP0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

2494701:FY206 RS07665
gene id: 2494701:FY206_RS07665
uniprot id: A0A5C1BXV7
names: Cofactor
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: The heme is bound between the two transmembrane subunits.

2494701:FY206 RS04295
gene id: 2494701:FY206_RS04295
uniprot id: A0A5C1BWZ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).

2494701:FY206 RS22895
gene id: 2494701:FY206_RS22895
uniprot id: A0A5C1C5I2
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

2494701:FY206 RS04600
gene id: 2494701:FY206_RS04600
uniprot id: A0A5C1BW56
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon.

2494701:FY206 RS04140
gene id: 2494701:FY206_RS04140
uniprot id: A0A5C1BVQ6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aldolase class II family. AraD/FucA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Homotetramer.
messages: Involved in the degradation of L-arabinose. Catalyzes the interconversion of L-ribulose 5-phosphate (LRu5P) and D-xylulose 5-phosphate (D-Xu5P) via a retroaldol/aldol mechanism (carbon-carbon bond cleavage analogous to a class II aldolase reaction).

2494701:FY206 RS06335
gene id: 2494701:FY206_RS06335
uniprot id: A0A5C1BXF3
names: Function
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. Cof family.
messages: Catalyzes the hydrolysis of 4-amino-2-methyl-5-hydroxymethylpyrimidine pyrophosphate (HMP-PP) to 4-amino-2-methyl-5-hydroxymethylpyrimidine phosphate (HMP-P).

2494701:FY206 RS00280
gene id: 2494701:FY206_RS00280
uniprot id: A0A5C1BUW4
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

2494701:FY206 RS24170
gene id: 2494701:FY206_RS24170
uniprot id: A0A5C1C5R2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fimbrial export usher family.
messages: Cell outer membrane
messages: Membrane

2494701:FY206 RS11690
gene id: 2494701:FY206_RS11690
uniprot id: A0A5C1BZI4
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

2494701:FY206 RS09950
gene id: 2494701:FY206_RS09950
uniprot id: A0A5C1BYV8
names: Function
names: Similarity
messages: Belongs to the transglycosylase MltG family.
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

2494701:FY206 RS07800
gene id: 2494701:FY206_RS07800
uniprot id: A0A5C1BY52
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

2494701:FY206 RS19545
gene id: 2494701:FY206_RS19545
uniprot id: A0A5C1C4T3
names: Function
names: Similarity
messages: Belongs to the APS kinase family.
messages: Catalyzes the synthesis of activated sulfate.

2494701:FY206 RS08990
gene id: 2494701:FY206_RS08990
uniprot id: A0A5C1BY96
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ribosome modulation factor family.
messages: Cytoplasm
messages: During stationary phase, converts 70S ribosomes to an inactive dimeric form (100S ribosomes).

2494701:FY206 RS06290
gene id: 2494701:FY206_RS06290
uniprot id: A0A5C1BX60
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

2494701:FY206 RS22405
gene id: 2494701:FY206_RS22405
uniprot id: A0A5C1C6G1
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

2494701:FY206 RS04675
gene id: 2494701:FY206_RS04675
uniprot id: A0A5C1BW13
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chloride channel (TC 2.A.49) family. ClcA subfamily.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Proton-coupled chloride transporter. Functions as antiport system and exchanges two chloride ions for 1 proton. Probably acts as an electrical shunt for an outwardly-directed proton pump that is linked to amino acid decarboxylation, as part of the extreme acid resistance (XAR) response.

2494701:FY206 RS13400
gene id: 2494701:FY206_RS13400
uniprot id: A0A5C1C0S7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 5 family.
messages: Periplasm

2494701:FY206 RS09845
gene id: 2494701:FY206_RS09845
uniprot id: A0A5C1BYT8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

2494701:FY206 RS20565
gene id: 2494701:FY206_RS20565
uniprot id: A0A5C1C5C2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Monomer.

2494701:FY206 RS16335
gene id: 2494701:FY206_RS16335
uniprot id: A0A5C1C2M5
names: Similarity
messages: Belongs to the alkylbase DNA glycosidase AlkA family.

2494701:FY206 RS16360
gene id: 2494701:FY206_RS16360
uniprot id: A0A5C1C2F3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. TCR/Tet family.
messages: Cell membrane
messages: Membrane

2494701:FY206 RS04005
gene id: 2494701:FY206_RS04005
uniprot id: A0A5C1BVS3
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

2494701:FY206 RS18360
gene id: 2494701:FY206_RS18360
uniprot id: A0A5C1C467
names: Similarity
messages: Belongs to the P(II) protein family.

2494701:FY206 RS01430
gene id: 2494701:FY206_RS01430
uniprot id: A0A5C1BUK1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell inner membrane
messages: Forms a membrane-associated complex with FtsE.
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in cellular division.

2494701:FY206 RS04610
gene id: 2494701:FY206_RS04610
uniprot id: A0A5C1BVY1
names: Similarity
messages: Belongs to the SfsA family.

2494701:FY206 RS16365
gene id: 2494701:FY206_RS16365
uniprot id: A0A5C1C375
names: Subcellular Location Annotation
messages: Cell inner membrane

2494701:FY206 RS21555
gene id: 2494701:FY206_RS21555
uniprot id: A0A5C1C8E2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetokinase family. TdcD subfamily.
messages: Catalyzes the conversion of propionyl phosphate and ADP to propionate and ATP.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2494701:FY206 RS10135
gene id: 2494701:FY206_RS10135
uniprot id: A0A5C1BZG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2494701:FY206 RS04230
gene id: 2494701:FY206_RS04230
uniprot id: A0A5C1C663
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2494701:FY206 RS04285
gene id: 2494701:FY206_RS04285
uniprot id: A0A5C1BVS4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

2494701:FY206 RS13505
gene id: 2494701:FY206_RS13505
uniprot id: A0A5C1C0U5
names: Subcellular Location Annotation
messages: Membrane

2494701:FY206 RS17380
gene id: 2494701:FY206_RS17380
uniprot id: A0A5C1C453
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell inner membrane
messages: Membrane

2494701:FY206 RS19830
gene id: 2494701:FY206_RS19830
uniprot id: A0A5C1C3V4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm

2494701:FY206 RS18050
gene id: 2494701:FY206_RS18050
uniprot id: A0A5C1C4F4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

2494701:FY206 RS00005
gene id: 2494701:FY206_RS00005
uniprot id: A0A5C1BTA5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

2494701:FY206 RS21825
gene id: 2494701:FY206_RS21825
uniprot id: A0A5C1C5M8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm

2494701:FY206 RS16085
gene id: 2494701:FY206_RS16085
uniprot id: A0A5C1C247
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Equilibrium between an active dimeric form, an inactive hexameric form and higher aggregates. Interconversion between the various forms is largely reversible and is influenced by the natural substrates and inhibitors of the enzyme.
messages: Feedback inhibited by histidine.

2494701:FY206 RS21365
gene id: 2494701:FY206_RS21365
uniprot id: A0A5C1C4M5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the periplasmic pilus chaperone family.
messages: Periplasm

2494701:FY206 RS19740
gene id: 2494701:FY206_RS19740
uniprot id: A0A5C1C3K4
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.

2494701:FY206 RS12780
gene id: 2494701:FY206_RS12780
uniprot id: A0A5C1C0M3
names: Subcellular Location Annotation
messages: Membrane

2494701:FY206 RS07535
gene id: 2494701:FY206_RS07535
uniprot id: A0A5C1BXD3
names: Similarity
messages: Belongs to the outer membrane porin (Opr) (TC 1.B.25) family.

2494701:FY206 RS21410
gene id: 2494701:FY206_RS21410
uniprot id: A0A5C1C5T5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FGGY kinase family.
messages: Catalyzes the phosphorylation of autoinducer-2 (AI-2) to phospho-AI-2, which subsequently inactivates the transcriptional regulator LsrR and leads to the transcription of the lsr operon. Phosphorylates the ring-open form of (S)-4,5-dihydroxypentane-2,3-dione (DPD), which is the precursor to all AI-2 signaling molecules, at the C5 position.
messages: Cytoplasm

2494701:FY206 RS23520
gene id: 2494701:FY206_RS23520
uniprot id: A0A5C1C5F4
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

2494701:FY206 RS12065
gene id: 2494701:FY206_RS12065
uniprot id: A0A5C1C150
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2494701:FY206 RS20705
gene id: 2494701:FY206_RS20705
uniprot id: A0A5C1C4E5
names: Similarity
messages: Belongs to the shaker potassium channel beta subunit family.

2494701:FY206 RS03880
gene id: 2494701:FY206_RS03880
uniprot id: A0A5C1BVS8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the YjjX NTPase family.
messages: Binds 1 divalent metal cation per subunit; can use either Mg(2+) or Mn(2+).
messages: Homodimer.
messages: Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA/RNA precursor pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

2494701:FY206 RS08430
gene id: 2494701:FY206_RS08430
uniprot id: A0A5C1BXS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

2494701:FY206 RS08760
gene id: 2494701:FY206_RS08760
uniprot id: A0A5C1BYB9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. YcaD (TC 2.A.1.26) family.
messages: Cell inner membrane
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

2494701:FY206 RS19090
gene id: 2494701:FY206_RS19090
uniprot id: A0A5C1C3A4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LuxS family.
messages: Binds 1 Fe cation per subunit.
messages: Homodimer.
messages: Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).

2494701:FY206 RS04575
gene id: 2494701:FY206_RS04575
uniprot id: A0A5C1BVZ4
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

2494701:FY206 RS06870
gene id: 2494701:FY206_RS06870
uniprot id: A0A5C1BXF2
names: Similarity
messages: Belongs to the RHS family.

2494701:FY206 RS06705
gene id: 2494701:FY206_RS06705
uniprot id: A0A5C1BX25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fimbrial export usher family.
messages: Cell outer membrane
messages: Membrane

2494701:FY206 RS19145
gene id: 2494701:FY206_RS19145
uniprot id: A0A5C1C3S0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

2494701:FY206 RS06220
gene id: 2494701:FY206_RS06220
uniprot id: A0A5C1BWT8
names: Subcellular Location Annotation
messages: Membrane

2494701:FY206 RS03410
gene id: 2494701:FY206_RS03410
uniprot id: A0A5C1BVC7
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

2494701:FY206 RS16080
gene id: 2494701:FY206_RS16080
uniprot id: A0A5C1C6J9
names: Function
names: Similarity
messages: Belongs to the HisL family.
messages: This protein is involved in the attenuation mechanism for the control of the expression of the his operon structural genes.

2494701:FY206 RS06155
gene id: 2494701:FY206_RS06155
uniprot id: A0A5C1BXV3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

2494701:FY206 RS21530
gene id: 2494701:FY206_RS21530
uniprot id: A0A5C1C4G3
names: Similarity
messages: Belongs to the pirin family.

2494701:FY206 RS13645
gene id: 2494701:FY206_RS13645
uniprot id: A0A5C1C0S3
names: Function
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.

2494701:FY206 RS07675
gene id: 2494701:FY206_RS07675
uniprot id: A0A5C1BXK4
names: Cofactor
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.

2494701:FY206 RS11410
gene id: 2494701:FY206_RS11410
uniprot id: A0A5C1BZJ6
names: Similarity
messages: Belongs to the glutamine synthetase family.

2494701:FY206 RS01110
gene id: 2494701:FY206_RS01110
uniprot id: A0A5C1BUD7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

2494701:FY206 RS11830
gene id: 2494701:FY206_RS11830
uniprot id: A0A5C1BZK9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2494701:FY206 RS19900
gene id: 2494701:FY206_RS19900
uniprot id: A0A5C1C4S5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Cell inner membrane
messages: Membrane

2494701:FY206 RS02715
gene id: 2494701:FY206_RS02715
uniprot id: A0A5C1BVC6
names: Cofactor
names: Function
names: Induction
names: Similarity
messages: Belongs to the aldolase class II family. AraD/FucA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of L-ribulose 5-phosphate to D-xylulose 5-phosphate. Is involved in the anaerobic L-ascorbate utilization.
messages: Induced by L-ascorbate. Repressed by UlaR.

2494701:FY206 RS14920
gene id: 2494701:FY206_RS14920
uniprot id: A0A5C1C6G2
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

2494701:FY206 RS00110
gene id: 2494701:FY206_RS00110
uniprot id: A0A5C1BTF1
names: Similarity
names: Subunit
messages: Belongs to the serine/threonine dehydratase family. DsdA subfamily.
messages: Monomer.

2494701:FY206 RS04300
gene id: 2494701:FY206_RS04300
uniprot id: A0A5C1BW72
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

2494701:FY206 RS17290
gene id: 2494701:FY206_RS17290
uniprot id: A0A5C1C2D3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 3 family.
messages: Periplasm

2494701:FY206 RS14475
gene id: 2494701:FY206_RS14475
uniprot id: A0A5C1C1C4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsbB family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein.

2494701:FY206 RS07070
gene id: 2494701:FY206_RS07070
uniprot id: A0A5C1C6K1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

2494701:FY206 RS17665
gene id: 2494701:FY206_RS17665
uniprot id: A0A5C1C2V0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel (TC 2.A.49) family.
messages: Cell membrane
messages: Membrane

2494701:FY206 RS06165
gene id: 2494701:FY206_RS06165
uniprot id: A0A5C1BWQ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
messages: Forms an icosahedral capsid composed of 60 subunits, arranged as a dodecamer of pentamers.

2494701:FY206 RS13685
gene id: 2494701:FY206_RS13685
uniprot id: A0A5C1C0H8
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

2494701:FY206 RS16850
gene id: 2494701:FY206_RS16850
uniprot id: A0A5C1C2E9
names: Similarity
messages: Belongs to the UPF0352 family.

2494701:FY206 RS06425
gene id: 2494701:FY206_RS06425
uniprot id: A0A5C1BWV9
names: Similarity
messages: Belongs to the FrmR/RcnR family.

2494701:FY206 RS07155
gene id: 2494701:FY206_RS07155
uniprot id: A0A5C1BXJ5
names: Cofactor
names: Similarity
messages: Belongs to the iron-containing alcohol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.

2494701:FY206 RS16350
gene id: 2494701:FY206_RS16350
uniprot id: A0A5C1C296
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. MdtB subfamily.
messages: Cell inner membrane
messages: Part of a tripartite efflux system composed of MdtA, MdtB and MdtC. MdtB forms a heteromultimer with MdtC.

2494701:FY206 RS01770
gene id: 2494701:FY206_RS01770
uniprot id: A0A5C1BUH8
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

2494701:FY206 RS18700
gene id: 2494701:FY206_RS18700
uniprot id: A0A5C1C4E3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamE family.
messages: Cell outer membrane
messages: Part of the Bam complex, which is composed of the outer membrane protein BamA, and four lipoproteins BamB, BamC, BamD and BamE.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

2494701:FY206 RS16310
gene id: 2494701:FY206_RS16310
uniprot id: A0A5C1C367
names: Similarity
messages: Belongs to the UPF0053 family.

2494701:FY206 RS22505
gene id: 2494701:FY206_RS22505
uniprot id: A0A5C1C6I1
names: Function
names: Similarity
messages: Belongs to the bacterioferritin family.
messages: Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex.

2494701:FY206 RS16250
gene id: 2494701:FY206_RS16250
uniprot id: A0A5C1C2D4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Nudix hydrolase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Hydrolyzes GDP-mannose.

2494701:FY206 RS08615
gene id: 2494701:FY206_RS08615
uniprot id: A0A5C1BYN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

2494701:FY206 RS04735
gene id: 2494701:FY206_RS04735
uniprot id: A0A5C1BW25
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

2494701:FY206 RS06260
gene id: 2494701:FY206_RS06260
uniprot id: A0A5C1BX43
names: Similarity
messages: Belongs to the BolA/IbaG family.

2494701:FY206 RS10285
gene id: 2494701:FY206_RS10285
uniprot id: A0A5C1BZ14
names: Similarity
messages: Belongs to the UPF0229 family.

2494701:FY206 RS19310
gene id: 2494701:FY206_RS19310
uniprot id: A0A5C1C7F9
names: Similarity
messages: Belongs to the HupF/HypC family.

2494701:FY206 RS04380
gene id: 2494701:FY206_RS04380
uniprot id: A0A5C1BWG6
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

2494701:FY206 RS08705
gene id: 2494701:FY206_RS08705
uniprot id: A0A5C1BY91
names: Subcellular Location Annotation
messages: Membrane

2494701:FY206 RS19800
gene id: 2494701:FY206_RS19800
uniprot id: A0A5C1C3L1
names: Subcellular Location Annotation
messages: Membrane

2494701:FY206 RS00120
gene id: 2494701:FY206_RS00120
uniprot id: A0A5C1BUT6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2494701:FY206 RS07670
gene id: 2494701:FY206_RS07670
uniprot id: A0A5C1BXW1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Two distinct, membrane-bound, FAD-containing enzymes are responsible for the catalysis of fumarate and succinate interconversion; the fumarate reductase is used in anaerobic growth, and the succinate dehydrogenase is used in aerobic growth.

2494701:FY206 RS12085
gene id: 2494701:FY206_RS12085
uniprot id: A0A5C1C0A8
names: Similarity
messages: Belongs to the FrmR/RcnR family.

2494701:FY206 RS21035
gene id: 2494701:FY206_RS21035
uniprot id: A0A5C1C444
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiK family.
messages: Cytoplasm
messages: Required for efficient ubiquinone (coenzyme Q) biosynthesis. UbiK is probably an accessory factor of Ubi enzymes and facilitates ubiquinone biosynthesis by acting as an assembly factor, a targeting factor, or both.

2494701:FY206 RS01750
gene id: 2494701:FY206_RS01750
uniprot id: A0A5C1C6G0
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

2494701:FY206 RS15375
gene id: 2494701:FY206_RS15375
uniprot id: A0A5C1C2Q6
names: Similarity
messages: Belongs to the DprA/Smf family.

2494701:FY206 RS23690
gene id: 2494701:FY206_RS23690
uniprot id: A0A5C1C706
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.

2494701:FY206 RS01270
gene id: 2494701:FY206_RS01270
uniprot id: A0A5C1BUA7
names: Cofactor
messages: Can also use Mn(2+) ion.

2494701:FY206 RS06955
gene id: 2494701:FY206_RS06955
uniprot id: A0A5C1BXG3
names: Similarity
messages: Belongs to the TPP enzyme family.

2494701:FY206 RS16755
gene id: 2494701:FY206_RS16755
uniprot id: A0A5C1C223
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Set transporter family.
messages: Membrane

2494701:FY206 RS21455
gene id: 2494701:FY206_RS21455
uniprot id: A0A5C1C608
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Uronate isomerase family.

2494701:FY206 RS18595
gene id: 2494701:FY206_RS18595
uniprot id: A0A5C1C4Q0
names: Function
names: Subcellular Location Annotation
messages: Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.
messages: Cytoplasm

2494701:FY206 RS05600
gene id: 2494701:FY206_RS05600
uniprot id: A0A5C1BWT6
names: Similarity
messages: Belongs to the YeeT/YkfH/YpjJ family.

2494701:FY206 RS10940
gene id: 2494701:FY206_RS10940
uniprot id: A0A5C1BZB8
names: Subcellular Location Annotation
messages: Membrane

2494701:FY206 RS07845
gene id: 2494701:FY206_RS07845
uniprot id: A0A5C1BXU8
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

2494701:FY206 RS08790
gene id: 2494701:FY206_RS08790
uniprot id: A0A5C1BZ71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

2494701:FY206 RS21930
gene id: 2494701:FY206_RS21930
uniprot id: A0A5C1C5P6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptF/LptG family.
messages: Component of the lipopolysaccharide transport and assembly complex. The LptBFG transporter is composed of two ATP-binding proteins (LptB) and two transmembrane proteins (LptF and LptG).
messages: Membrane
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane.

2494701:FY206 RS23680
gene id: 2494701:FY206_RS23680
uniprot id: A0A5C1C6L3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WzzB/Cld/Rol family.
messages: Cell inner membrane
messages: Membrane
messages: Modulates the polysaccharide chain length of enterobacterial common antigen (ECA).
messages: Probably part of a complex composed of WzxE, WzyE and WzzE.

2494701:FY206 RS20230
gene id: 2494701:FY206_RS20230
uniprot id: A0A5C1C412
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IPP isomerase type 1 family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium ion binds only when substrate is bound.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).
messages: Cytoplasm
messages: Homodimer.

2494701:FY206 RS19660
gene id: 2494701:FY206_RS19660
uniprot id: A0A5C1C3S7
names: Subcellular Location Annotation
messages: Membrane

2494701:FY206 RS22985
gene id: 2494701:FY206_RS22985
uniprot id: A0A5C1C6M3
names: Function
names: Similarity
messages: Belongs to the polysaccharide deacetylase family. ArnD deformylase subfamily.
messages: Catalyzes the deformylation of 4-deoxy-4-formamido-L-arabinose-phosphoundecaprenol to 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.

2494701:FY206 RS11530
gene id: 2494701:FY206_RS11530
uniprot id: A0A5C1C6P0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2494701:FY206 RS16530
gene id: 2494701:FY206_RS16530
uniprot id: A0A5C1C2H7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

2494701:FY206 RS10405
gene id: 2494701:FY206_RS10405
uniprot id: A0A5C1BZC5
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

2494701:FY206 RS23590
gene id: 2494701:FY206_RS23590
uniprot id: A0A5C1C5S0
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

2494701:FY206 RS07565
gene id: 2494701:FY206_RS07565
uniprot id: A0A5C1BXU1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SeqA family.
messages: Cytoplasm
messages: Homodimer. Polymerizes to form helical filaments.
messages: Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re-initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated.

2494701:FY206 RS04315
gene id: 2494701:FY206_RS04315
uniprot id: A0A5C1BW11
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell membrane
messages: Self-interacts. Interacts with FtsZ.

2494701:FY206 RS18295
gene id: 2494701:FY206_RS18295
uniprot id: A0A5C1C2V1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HesB/IscA family.
messages: Binds 2 iron ions per dimer. The dimer may bind additional iron ions.
messages: Homodimer; may form tetramers and higher multimers.
messages: Is able to transfer iron-sulfur clusters to apo-ferredoxin. Multiple cycles of [2Fe2S] cluster formation and transfer are observed, suggesting that IscA acts catalytically. Recruits intracellular free iron so as to provide iron for the assembly of transient iron-sulfur cluster in IscU in the presence of IscS, L-cysteine and the thioredoxin reductase system TrxA/TrxB.

2494701:FY206 RS16650
gene id: 2494701:FY206_RS16650
uniprot id: A0A5C1C204
names: Subcellular Location Annotation
messages: Membrane

2494701:FY206 RS18530
gene id: 2494701:FY206_RS18530
uniprot id: A0A5C1C6L5
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-II family.

2494701:FY206 RS04275
gene id: 2494701:FY206_RS04275
uniprot id: A0A5C1BW26
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

2494701:FY206 RS09530
gene id: 2494701:FY206_RS09530
uniprot id: A0A5C1BYQ4
names: Similarity
messages: Belongs to the pirin family.

2494701:FY206 RS05715
gene id: 2494701:FY206_RS05715
uniprot id: A0A5C1BWV5
names: Similarity
messages: Belongs to the diol/glycerol dehydratase large subunit family.

2494701:FY206 RS03015
gene id: 2494701:FY206_RS03015
uniprot id: A0A5C1BV56
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIIB subfamily.
messages: Cell inner membrane
messages: Mediates magnesium influx to the cytosol.

2494701:FY206 RS20310
gene id: 2494701:FY206_RS20310
uniprot id: A0A5C1C4Y8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

2494701:FY206 RS13935
gene id: 2494701:FY206_RS13935
uniprot id: A0A5C1C0N0
names: Caution
names: Similarity
messages: Belongs to the NTE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2494701:FY206 RS02170
gene id: 2494701:FY206_RS02170
uniprot id: A0A5C1BUX5
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

2494701:FY206 RS04290
gene id: 2494701:FY206_RS04290
uniprot id: A0A5C1BVS2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. FtsW subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell division.

2494701:FY206 RS10145
gene id: 2494701:FY206_RS10145
uniprot id: A0A5C1BZ77
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M20B family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Cleaves the N-terminal amino acid of tripeptides.
messages: Cytoplasm

2494701:FY206 RS03770
gene id: 2494701:FY206_RS03770
uniprot id: A0A5C1BVH3
names: Similarity
messages: Belongs to the organic radical-activating enzymes family.

2494701:FY206 RS04515
gene id: 2494701:FY206_RS04515
uniprot id: A0A5C1BX35
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

2494701:FY206 RS21625
gene id: 2494701:FY206_RS21625
uniprot id: A0A5C1C635
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

2494701:FY206 RS20090
gene id: 2494701:FY206_RS20090
uniprot id: A0A5C1C5D9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TER reductase family.
messages: Involved in the final reduction of the elongation cycle of fatty acid synthesis (FAS II). Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP).
messages: Monomer.

2494701:FY206 RS12480
gene id: 2494701:FY206_RS12480
uniprot id: A0A5C1BZW3
names: Subcellular Location Annotation
messages: Membrane

2494701:FY206 RS09140
gene id: 2494701:FY206_RS09140
uniprot id: A0A5C1C6D1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family.
messages: Membrane

2494701:FY206 RS10420
gene id: 2494701:FY206_RS10420
uniprot id: A0A5C1BZX3
names: Function
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family. AstD subfamily.
messages: Catalyzes the NAD-dependent reduction of succinylglutamate semialdehyde into succinylglutamate.

2494701:FY206 RS22365
gene id: 2494701:FY206_RS22365
uniprot id: A0A5C1C584
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

2494701:FY206 RS19075
gene id: 2494701:FY206_RS19075
uniprot id: A0A5C1C3R0
names: Subcellular Location Annotation
messages: Membrane

2494701:FY206 RS14895
gene id: 2494701:FY206_RS14895
uniprot id: A0A5C1C141
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FlhC family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways.
messages: Heterohexamer composed of two FlhC and four FlhD subunits. Each FlhC binds a FlhD dimer, forming a heterotrimer, and a hexamer assembles by dimerization of two heterotrimers.

2494701:FY206 RS19780
gene id: 2494701:FY206_RS19780
uniprot id: A0A5C1C3P2
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD.
messages: Belongs to the RecD family.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding.

2494701:FY206 RS04490
gene id: 2494701:FY206_RS04490
uniprot id: A0A5C1BW63
names: Function
names: Similarity
names: Subunit
messages: Belongs to the spermidine/spermine synthase family.
messages: Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
messages: Homodimer or homotetramer.

2494701:FY206 RS04080
gene id: 2494701:FY206_RS04080
uniprot id: A0A5C1BWT3
names: Function
names: Similarity
messages: Belongs to the Ap4A hydrolase family.
messages: Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP.

2494701:FY206 RS22500
gene id: 2494701:FY206_RS22500
uniprot id: A0A5C1C4U9
names: Similarity
messages: Belongs to the peptidase A24 family.

2494701:FY206 RS16960
gene id: 2494701:FY206_RS16960
uniprot id: A0A5C1C270
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Gram-negative porin family.
messages: Cell outer membrane
messages: Homotrimer.
messages: Membrane

2494701:FY206 RS11965
gene id: 2494701:FY206_RS11965
uniprot id: A0A5C1C095
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

2494701:FY206 RS23305
gene id: 2494701:FY206_RS23305
uniprot id: A0A5C1C6W1
names: Similarity
messages: Belongs to the glycosyl hydrolase 8 (cellulase D) family.

2494701:FY206 RS11620
gene id: 2494701:FY206_RS11620
uniprot id: A0A5C1BZG8
names: Subcellular Location Annotation
messages: Membrane

2494701:FY206 RS04030
gene id: 2494701:FY206_RS04030
uniprot id: A0A5C1BW16
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

2494701:FY206 RS12305
gene id: 2494701:FY206_RS12305
uniprot id: A0A5C1C036
names: Subcellular Location Annotation
messages: Membrane

2494701:FY206 RS20970
gene id: 2494701:FY206_RS20970
uniprot id: A0A5C1C4C7
names: Function
names: Similarity
names: Subunit
messages: Acts on ADP-mannose and ADP-glucose as well as ADP-ribose. Prevents glycogen biosynthesis. The reaction catalyzed by this enzyme is a limiting step of the gluconeogenic process.
messages: Belongs to the Nudix hydrolase family. NudF subfamily.
messages: Homodimer.

2494701:FY206 RS17300
gene id: 2494701:FY206_RS17300
uniprot id: A0A5C1C2K6
names: Caution
names: Function
names: Similarity
messages: Belongs to the UbiX/PAD1 family.
messages: Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2494701:FY206 RS05490
gene id: 2494701:FY206_RS05490
uniprot id: A0A5C1BXJ4
names: Similarity
messages: Belongs to the FrmR/RcnR family.

2494701:FY206 RS01115
gene id: 2494701:FY206_RS01115
uniprot id: A0A5C1BUY2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2494701:FY206 RS16830
gene id: 2494701:FY206_RS16830
uniprot id: A0A5C1C2H1
names: Similarity
names: Subunit
messages: Belongs to the pseudouridine synthase RsuA family.
messages: Monomer.

2494701:FY206 RS17440
gene id: 2494701:FY206_RS17440
uniprot id: A0A5C1C2G4
names: Subcellular Location Annotation
messages: Membrane

2494701:FY206 RS14095
gene id: 2494701:FY206_RS14095
uniprot id: A0A5C1C201
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

2494701:FY206 RS12720
gene id: 2494701:FY206_RS12720
uniprot id: A0A5C1C0B7
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

2494701:FY206 RS09205
gene id: 2494701:FY206_RS09205
uniprot id: A0A5C1BYY5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia.

2494701:FY206 RS11560
gene id: 2494701:FY206_RS11560
uniprot id: A0A5C1BZF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

2494701:FY206 RS10450
gene id: 2494701:FY206_RS10450
uniprot id: A0A5C1BZ97
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
messages: Homodimer.

2494701:FY206 RS24285
gene id: 2494701:FY206_RS24285
uniprot id: A0A5C1C791
names: Function
names: Similarity
messages: Belongs to the aldolase LacD family.
messages: Cleaves 6-deoxy-6-sulfo-D-fructose 1-phosphate (SFP) to form dihydroxyacetone phosphate (DHAP) and 3-sulfolactaldehyde (SLA).

2494701:FY206 RS08585
gene id: 2494701:FY206_RS08585
uniprot id: A0A5C1BXU5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HCP family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 hybrid [4Fe-2O-2S] cluster.
messages: Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
messages: Cytoplasm

2494701:FY206 RS22325
gene id: 2494701:FY206_RS22325
uniprot id: A0A5C1C4V5
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

2494701:FY206 RS08440
gene id: 2494701:FY206_RS08440
uniprot id: A0A5C1BYB2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 3 family.
messages: Periplasm

2494701:FY206 RS11075
gene id: 2494701:FY206_RS11075
uniprot id: A0A5C1BZ96
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RnfG family.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

2494701:FY206 RS24115
gene id: 2494701:FY206_RS24115
uniprot id: A0A5C1C636
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the rhamnose isomerase family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the interconversion of L-rhamnose and L-rhamnulose.
messages: Cytoplasm
messages: Homotetramer.

2494701:FY206 RS20270
gene id: 2494701:FY206_RS20270
uniprot id: A0A5C1C5G6
names: Similarity
messages: Belongs to the SdhE FAD assembly factor family.

2494701:FY206 RS01720
gene id: 2494701:FY206_RS01720
uniprot id: A0A5C1BUI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the hok/gef family.
messages: Cell inner membrane

2494701:FY206 RS06810
gene id: 2494701:FY206_RS06810
uniprot id: A0A5C1BXN7
names: Similarity
messages: Belongs to the nitroreductase family.

2494701:FY206 RS15955
gene id: 2494701:FY206_RS15955
uniprot id: A0A5C1C1M1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YkuD family.
messages: Periplasm

2494701:FY206 RS20795
gene id: 2494701:FY206_RS20795
uniprot id: A0A5C1C4F8
names: Similarity
messages: Belongs to the FrmR/RcnR family.

2494701:FY206 RS01625
gene id: 2494701:FY206_RS01625
uniprot id: A0A5C1BUR8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class B bacterial acid phosphatase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homotetramer.
messages: Periplasm

2494701:FY206 RS07585
gene id: 2494701:FY206_RS07585
uniprot id: A0A5C1BXR9
names: Function
names: Induction
names: Similarity
names: Subunit
messages: A small protein (arrest peptide) encoded upstream of inducible ornithine carboxylase gene (speF) that controls expression of downstream genes (usually speF and potE) by transcriptional and translational attenuation.
messages: Belongs to the speF operon leader peptide family.
messages: Binds ornithine in stalled 70S ribosomes, blocking the upper two-thirds of the exit tunnel. Contacts 23S rRNA and ribosomal proteins L4 and L22.
messages: Induced by ornithine, repressed by putrescine. Part of the speFL-speF-potE operon.

2494701:FY206 RS14600
gene id: 2494701:FY206_RS14600
uniprot id: A0A5C1C168
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Cytoplasm
messages: Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA.

2494701:FY206 RS24470
gene id: 2494701:FY206_RS24470
uniprot id: A0A5C1C684
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. AsnA subfamily.
messages: Cytoplasm

2494701:FY206 RS07405
gene id: 2494701:FY206_RS07405
uniprot id: A0A5C1BXN4
names: Function
names: Similarity
messages: Belongs to the IUNH family. RihA subfamily.
messages: Hydrolyzes cytidine or uridine to ribose and cytosine or uracil, respectively.

2494701:FY206 RS14385
gene id: 2494701:FY206_RS14385
uniprot id: A0A5C1C251
names: Function
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
messages: Catalyzes the oxidative phosphorylation of glyceraldehyde 3-phosphate (G3P) to 1,3-bisphosphoglycerate (BPG) using the cofactor NAD. The first reaction step involves the formation of a hemiacetal intermediate between G3P and a cysteine residue, and this hemiacetal intermediate is then oxidized to a thioester, with concomitant reduction of NAD to NADH. The reduced NADH is then exchanged with the second NAD, and the thioester is attacked by a nucleophilic inorganic phosphate to produce BPG.

2494701:FY206 RS24530
gene id: 2494701:FY206_RS24530
uniprot id: A0A5C1C5X0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

2494701:FY206 RS09445
gene id: 2494701:FY206_RS09445
uniprot id: A0A5C1BZG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.
messages: Membrane

2494701:FY206 RS16340
gene id: 2494701:FY206_RS16340
uniprot id: A0A5C1C374
names: Similarity
messages: Belongs to the heat shock protein 70 family.

2494701:FY206 RS17840
gene id: 2494701:FY206_RS17840
uniprot id: A0A5C1C301
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

2494701:FY206 RS23925
gene id: 2494701:FY206_RS23925
uniprot id: A0A5C1C5S4
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

2494701:FY206 RS23710
gene id: 2494701:FY206_RS23710
uniprot id: A0A5C1C5I5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. UvrD subfamily.
messages: Homodimer.
messages: Rep helicase is a single-stranded DNA-dependent ATPase involved in DNA replication; it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction.

2494701:FY206 RS07935
gene id: 2494701:FY206_RS07935
uniprot id: A0A5C1BXK2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

2494701:FY206 RS04215
gene id: 2494701:FY206_RS04215
uniprot id: A0A5C1BW17
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

2494701:FY206 RS02525
gene id: 2494701:FY206_RS02525
uniprot id: A0A5C1BV72
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. EpmA subfamily.
messages: Homodimer.
messages: With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta-lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P.

2494701:FY206 RS10080
gene id: 2494701:FY206_RS10080
uniprot id: A0A5C1BZ03
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

2494701:FY206 RS08310
gene id: 2494701:FY206_RS08310
uniprot id: A0A5C1BYF0
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

2494701:FY206 RS23285
gene id: 2494701:FY206_RS23285
uniprot id: A0A5C1C6E9
names: Similarity
messages: Belongs to the peptidase M16 family.

2494701:FY206 RS01000
gene id: 2494701:FY206_RS01000
uniprot id: A0A5C1BU14
names: Subcellular Location Annotation
messages: Membrane

2494701:FY206 RS22825
gene id: 2494701:FY206_RS22825
uniprot id: A0A5C1C6J4
names: Similarity
messages: Belongs to the FeoA family.

2494701:FY206 RS06000
gene id: 2494701:FY206_RS06000
uniprot id: A0A5C1BWK8
names: Similarity
messages: Belongs to the alkaline phosphatase family.

2494701:FY206 RS01440
gene id: 2494701:FY206_RS01440
uniprot id: A0A5C1BUR5
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

2494701:FY206 RS24685
gene id: 2494701:FY206_RS24685
uniprot id: A0A5C1C6Y9
names: Subcellular Location Annotation
messages: Membrane

2494701:FY206 RS23930
gene id: 2494701:FY206_RS23930
uniprot id: A0A5C1C736
names: Similarity
names: Subunit
messages: Homotetramer.
messages: In the C-terminal section; belongs to the homoserine dehydrogenase family.
messages: In the N-terminal section; belongs to the aspartokinase family.

2494701:FY206 RS08500
gene id: 2494701:FY206_RS08500
uniprot id: A0A5C1BXW5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GSP G family.
messages: Cell inner membrane
messages: Membrane
messages: Type II secretion system is composed of four main components: the outer membrane complex, the inner membrane complex, the cytoplasmic secretion ATPase and the periplasm-spanning pseudopilus. Forms homomultimers.

2494701:FY206 RS08395
gene id: 2494701:FY206_RS08395
uniprot id: A0A5C1BXU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2494701:FY206 RS24925
gene id: 2494701:FY206_RS24925
uniprot id: A0A5C1C987
names: Similarity
messages: Belongs to the UPF0401 family.

2494701:FY206 RS14010
gene id: 2494701:FY206_RS14010
uniprot id: A0A5C1C1Z7
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.

2494701:FY206 RS09995
gene id: 2494701:FY206_RS09995
uniprot id: A0A5C1C042
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LpoB family.
messages: Interacts with PBP1b.
messages: Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b).

2494701:FY206 RS05685
gene id: 2494701:FY206_RS05685
uniprot id: A0A5C1BWR6
names: Cofactor
names: Similarity
messages: Belongs to the iron-containing alcohol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.

2494701:FY206 RS09000
gene id: 2494701:FY206_RS09000
uniprot id: A0A5C1BZA6
names: Similarity
messages: Belongs to the peptidase S16 family.

2494701:FY206 RS10100
gene id: 2494701:FY206_RS10100
uniprot id: A0A5C1BYR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

2494701:FY206 RS16985
gene id: 2494701:FY206_RS16985
uniprot id: A0A5C1C267
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Autophosphorylated. Activation probably requires a transfer of a phosphate group from a His in the transmitter domain to an Asp in the receiver domain.
messages: Belongs to the RcsC family.
messages: Cell inner membrane
messages: Component of the Rcs signaling system, which controls transcription of numerous genes. RcsC functions as a membrane-associated protein kinase that phosphorylates RcsD in response to environmental signals. The phosphoryl group is then transferred to the response regulator RcsB.
messages: Interacts with RcsD.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

2494701:FY206 RS09615
gene id: 2494701:FY206_RS09615
uniprot id: A0A5C1BYF5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acyltransferase 3 family. OpgC subfamily.
messages: Cell membrane
messages: Necessary for the succinyl substitution of periplasmic glucans. Could catalyze the transfer of succinyl residues from the cytoplasmic side of the membrane to the nascent glucan backbones on the periplasmic side of the membrane.

2494701:FY206 RS23815
gene id: 2494701:FY206_RS23815
uniprot id: A0A5C1C5X6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family. BtuB (TC 1.B.14.3.1) subfamily.
messages: Cell outer membrane
messages: Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2494701:FY206 RS21485
gene id: 2494701:FY206_RS21485
uniprot id: A0A5C1C4T7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MzrA family.
messages: Cell inner membrane
messages: Interacts with EnvZ.
messages: Modulates the activity of the EnvZ/OmpR two-component regulatory system, probably by directly modulating EnvZ enzymatic activity and increasing stability of phosphorylated OmpR.

2494701:FY206 RS10780
gene id: 2494701:FY206_RS10780
uniprot id: A0A5C1BZE2
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

2494701:FY206 RS10920
gene id: 2494701:FY206_RS10920
uniprot id: A0A5C1BZ51
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

2494701:FY206 RS19220
gene id: 2494701:FY206_RS19220
uniprot id: A0A5C1C4Z8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase family.
messages: Cytoplasm
messages: One of at least two accessory proteins for anaerobic nitric oxide (NO) reductase. Reduces the rubredoxin moiety of NO reductase.

2494701:FY206 RS13970
gene id: 2494701:FY206_RS13970
uniprot id: A0A5C1C121
names: Subcellular Location Annotation
messages: Membrane

2494701:FY206 RS13670
gene id: 2494701:FY206_RS13670
uniprot id: A0A5C1C0L5
names: Similarity
messages: Belongs to the peptidase S49 family.

2494701:FY206 RS24000
gene id: 2494701:FY206_RS24000
uniprot id: A0A5C1C5N5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

2494701:FY206 RS08240
gene id: 2494701:FY206_RS08240
uniprot id: A0A5C1BXR7
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

2494701:FY206 RS06065
gene id: 2494701:FY206_RS06065
uniprot id: A0A5C1BWN7
names: Function
messages: This protein is a positive regulator for the phosphate regulon. Transcription of this operon is positively regulated by PhoB and PhoR when phosphate is limited.

2494701:FY206 RS19690
gene id: 2494701:FY206_RS19690
uniprot id: A0A5C1C3J6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family. QueF type 2 subfamily.
messages: Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
messages: Cytoplasm
messages: Homodimer.

2494701:FY206 RS19205
gene id: 2494701:FY206_RS19205
uniprot id: A0A5C1C3J5
names: Similarity
names: Subunit
messages: Belongs to the SIS family. GutQ/KpsF subfamily.
messages: Homotetramer.

2494701:FY206 RS10340
gene id: 2494701:FY206_RS10340
uniprot id: A0A5C1BZ45
names: Cofactor
names: Similarity
messages: Belongs to the nitroreductase family.
messages: Binds 1 FMN per subunit.

2494701:FY206 RS12570
gene id: 2494701:FY206_RS12570
uniprot id: A0A5C1C097
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell outer membrane
messages: Membrane

2494701:FY206 RS01875
gene id: 2494701:FY206_RS01875
uniprot id: A0A5C1BUM3
names: Similarity
messages: Belongs to the phosphate/phosphite/phosphonate binding protein family.

2494701:FY206 RS22090
gene id: 2494701:FY206_RS22090
uniprot id: A0A5C1C5S1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AaeX family.
messages: Cell membrane

2494701:FY206 RS21655
gene id: 2494701:FY206_RS21655
uniprot id: A0A5C1C5K0
names: Function
names: Similarity
messages: Belongs to the UbiT family.
messages: Required for O(2)-independent ubiquinone (coenzyme Q) biosynthesis. Likely functions as an accessory factor.

2494701:FY206 RS22545
gene id: 2494701:FY206_RS22545
uniprot id: A0A5C1C4W1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DsrE/TusD family.
messages: Cytoplasm
messages: Heterohexamer, formed by a dimer of trimers. The hexameric TusBCD complex contains 2 copies each of TusB, TusC and TusD. The TusBCD complex interacts with TusE.
messages: Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE.

2494701:FY206 RS14455
gene id: 2494701:FY206_RS14455
uniprot id: A0A5C1C0Y7
names: Function
names: Similarity
messages: Belongs to the DadA oxidoreductase family.
messages: Oxidative deamination of D-amino acids.

2494701:FY206 RS17675
gene id: 2494701:FY206_RS17675
uniprot id: A0A5C1C2K7
names: Similarity
messages: Belongs to the shaker potassium channel beta subunit family.

2494701:FY206 RS22990
gene id: 2494701:FY206_RS22990
uniprot id: A0A5C1C5K1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto-arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido-arabinose (UDP-L-Ara4FN). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.
messages: Homohexamer, formed by a dimer of trimers.
messages: In the C-terminal section; belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily.
messages: In the N-terminal section; belongs to the Fmt family. UDP-L-Ara4N formyltransferase subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2494701:FY206 RS06995
gene id: 2494701:FY206_RS06995
uniprot id: A0A5C1BXI7
names: Subcellular Location Annotation
messages: Membrane

2494701:FY206 RS23645
gene id: 2494701:FY206_RS23645
uniprot id: A0A5C1C5U4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WzyE family.
messages: Cell inner membrane
messages: Probably involved in the polymerization of enterobacterial common antigen (ECA) trisaccharide repeat units.
messages: Probably part of a complex composed of WzxE, WzyE and WzzE.

2494701:FY206 RS08730
gene id: 2494701:FY206_RS08730
uniprot id: A0A5C1BY51
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LolA family.
messages: Monomer.
messages: Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).
messages: Periplasm

2494701:FY206 RS05065
gene id: 2494701:FY206_RS05065
uniprot id: A0A5C1BWE1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Membrane
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

2494701:FY206 RS16725
gene id: 2494701:FY206_RS16725
uniprot id: A0A5C1C210
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2494701:FY206 RS24625
gene id: 2494701:FY206_RS24625
uniprot id: A0A5C1C6A8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.

2494701:FY206 RS00485
gene id: 2494701:FY206_RS00485
uniprot id: A0A5C1BTU7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

2494701:FY206 RS17770
gene id: 2494701:FY206_RS17770
uniprot id: A0A5C1C4B1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2494701:FY206 RS19855
gene id: 2494701:FY206_RS19855
uniprot id: A0A5C1C3M2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. LplT (TC 2.A.1.42) family.
messages: Catalyzes the facilitated diffusion of 2-acyl-glycero-3-phosphoethanolamine (2-acyl-GPE) into the cell.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2494701:FY206 RS15890
gene id: 2494701:FY206_RS15890
uniprot id: A0A5C1C305
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

2494701:FY206 RS01045
gene id: 2494701:FY206_RS01045
uniprot id: A0A5C1BUJ7
names: Subcellular Location Annotation
messages: Membrane

2494701:FY206 RS19435
gene id: 2494701:FY206_RS19435
uniprot id: A0A5C1C530
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

2494701:FY206 RS22040
gene id: 2494701:FY206_RS22040
uniprot id: A0A5C1C5R0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1C family.
messages: Periplasm

2494701:FY206 RS00965
gene id: 2494701:FY206_RS00965
uniprot id: A0A5C1BUE6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

2494701:FY206 RS13990
gene id: 2494701:FY206_RS13990
uniprot id: A0A5C1C114
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
messages: Cell membrane
messages: Membrane

2494701:FY206 RS04360
gene id: 2494701:FY206_RS04360
uniprot id: A0A5C1BVV5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family. GuaC type 1 subfamily.
messages: Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.
messages: Homotetramer.

2494701:FY206 RS06520
gene id: 2494701:FY206_RS06520
uniprot id: A0A5C1BX85
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

2494701:FY206 RS04505
gene id: 2494701:FY206_RS04505
uniprot id: A0A5C1BVW5
names: Similarity
messages: Belongs to the bacterial PQQ dehydrogenase family.

2494701:FY206 RS17110
gene id: 2494701:FY206_RS17110
uniprot id: A0A5C1C2J9
names: Subcellular Location Annotation
messages: Membrane

2494701:FY206 RS22470
gene id: 2494701:FY206_RS22470
uniprot id: A0A5C1C566
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

2494701:FY206 RS15930
gene id: 2494701:FY206_RS15930
uniprot id: A0A5C1C1L5
names: Subcellular Location Annotation
messages: Membrane

2494701:FY206 RS04700
gene id: 2494701:FY206_RS04700
uniprot id: A0A5C1BWB1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dGTPase family. Type 1 subfamily.
messages: Homotetramer.
messages: dGTPase preferentially hydrolyzes dGTP over the other canonical NTPs.

2494701:FY206 RS20410
gene id: 2494701:FY206_RS20410
uniprot id: A0A5C1C405
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

2494701:FY206 RS10005
gene id: 2494701:FY206_RS10005
uniprot id: A0A5C1C6K2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 3 family. NagZ subfamily.
messages: Cytoplasm
messages: Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides.

2494701:FY206 RS06285
gene id: 2494701:FY206_RS06285
uniprot id: A0A5C1BX21
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

2494701:FY206 RS08525
gene id: 2494701:FY206_RS08525
uniprot id: A0A5C1BYC0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP L family.
messages: Cell inner membrane
messages: Inner membrane component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm.
messages: Membrane

2494701:FY206 RS20520
gene id: 2494701:FY206_RS20520
uniprot id: A0A5C1C4C2
names: Similarity
messages: Belongs to the GSP E family.

2494701:FY206 RS24665
gene id: 2494701:FY206_RS24665
uniprot id: A0A5C1C8I9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

2494701:FY206 RS04640
gene id: 2494701:FY206_RS04640
uniprot id: A0A5C1BWL2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fimbrial export usher family.
messages: Cell outer membrane
messages: Membrane

2494701:FY206 RS19035
gene id: 2494701:FY206_RS19035
uniprot id: A0A5C1C3H0
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

2494701:FY206 RS17265
gene id: 2494701:FY206_RS17265
uniprot id: A0A5C1C2D1
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

2494701:FY206 RS09595
gene id: 2494701:FY206_RS09595
uniprot id: A0A5C1BZ74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CsgA/CsgB family.
messages: Fimbrium

2494701:FY206 RS21725
gene id: 2494701:FY206_RS21725
uniprot id: A0A5C1C4F6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

2494701:FY206 RS18650
gene id: 2494701:FY206_RS18650
uniprot id: A0A5C1C4B4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

2494701:FY206 RS02635
gene id: 2494701:FY206_RS02635
uniprot id: A0A5C1BVM2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm
messages: Monomer.

2494701:FY206 RS05090
gene id: 2494701:FY206_RS05090
uniprot id: A0A5C1BW85
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily.
messages: Cell membrane
messages: Homotetramer.
messages: Purine salvage pathway enzyme that catalyzes the transfer of the ribosyl-5-phosphate group from 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to the N9 position of the 6-oxopurines guanine and xanthine to form the corresponding ribonucleotides GMP (guanosine 5'-monophosphate) and XMP (xanthosine 5'-monophosphate), with the release of PPi. To a lesser extent, also acts on hypoxanthine.

2494701:FY206 RS07680
gene id: 2494701:FY206_RS07680
uniprot id: A0A5C1BXC7
names: Function
names: Similarity
messages: Belongs to the alpha-ketoglutarate dehydrogenase family.
messages: E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

2494701:FY206 RS08775
gene id: 2494701:FY206_RS08775
uniprot id: A0A5C1BYG9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycyl radical enzyme (GRE) family. PFL subfamily.
messages: Cytoplasm
messages: Homodimer.

2494701:FY206 RS24495
gene id: 2494701:FY206_RS24495
uniprot id: A0A5C1C6A0
names: Subcellular Location Annotation
messages: Membrane

2494701:FY206 RS17900
gene id: 2494701:FY206_RS17900
uniprot id: A0A5C1C2V5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 1 subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

2494701:FY206 RS05025
gene id: 2494701:FY206_RS05025
uniprot id: A0A5C1BW44
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

2494701:FY206 RS08230
gene id: 2494701:FY206_RS08230
uniprot id: A0A5C1BYX6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transaldolase family. Type 3A subfamily.
messages: Catalyzes the reversible formation of fructose 6-phosphate from dihydroxyacetone and D-glyceraldehyde 3-phosphate via an aldolization reaction.
messages: Cytoplasm
messages: Homodecamer.

2494701:FY206 RS04635
gene id: 2494701:FY206_RS04635
uniprot id: A0A5C1BW68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the periplasmic pilus chaperone family.
messages: Periplasm

2494701:FY206 RS03925
gene id: 2494701:FY206_RS03925
uniprot id: A0A5C1BVL5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA.
messages: Cytoplasm
messages: Homodimer.

2494701:FY206 RS22815
gene id: 2494701:FY206_RS22815
uniprot id: A0A5C1C511
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family. GreB subfamily.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length.

2494701:FY206 RS19635
gene id: 2494701:FY206_RS19635
uniprot id: A0A5C1C3J4
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily.
messages: Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA.

2494701:FY206 RS24105
gene id: 2494701:FY206_RS24105
uniprot id: A0A5C1C632
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Activates expression of the rhaBAD and rhaT operons.
messages: Binds DNA as a dimer.
messages: Cytoplasm

2494701:FY206 RS15545
gene id: 2494701:FY206_RS15545
uniprot id: A0A5C1C1Q2
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

2494701:FY206 RS15200
gene id: 2494701:FY206_RS15200
uniprot id: A0A5C1C1F3
names: Similarity
messages: Belongs to the glycosyl hydrolase 24 family.

2494701:FY206 RS08805
gene id: 2494701:FY206_RS08805
uniprot id: A0A5C1BYA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

2494701:FY206 RS04240
gene id: 2494701:FY206_RS04240
uniprot id: A0A5C1BVR2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

2494701:FY206 RS17875
gene id: 2494701:FY206_RS17875
uniprot id: A0A5C1C4D2
names: Similarity
messages: Belongs to the acetyltransferase family. YpeA subfamily.

2494701:FY206 RS23405
gene id: 2494701:FY206_RS23405
uniprot id: A0A5C1C6Q6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M24B family. Bacterial-type prolidase subfamily.
messages: Binds 2 manganese ions per subunit.
messages: Splits dipeptides with a prolyl residue in the C-terminal position.

2494701:FY206 RS09770
gene id: 2494701:FY206_RS09770
uniprot id: A0A5C1BYL3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Homodimer.

2494701:FY206 RS08710
gene id: 2494701:FY206_RS08710
uniprot id: A0A5C1BYA8
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

2494701:FY206 RS12765
gene id: 2494701:FY206_RS12765
uniprot id: A0A5C1BZZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Cell inner membrane

2494701:FY206 RS00675
gene id: 2494701:FY206_RS00675
uniprot id: A0A5C1BUP9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the zinc-containing alcohol dehydrogenase family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate.
messages: Cytoplasm
messages: Homotetramer.

2494701:FY206 RS04320
gene id: 2494701:FY206_RS04320
uniprot id: A0A5C1BWF6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

2494701:FY206 RS07015
gene id: 2494701:FY206_RS07015
uniprot id: A0A5C1BYB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the periplasmic pilus chaperone family.
messages: Periplasm

2494701:FY206 RS11060
gene id: 2494701:FY206_RS11060
uniprot id: A0A5C1BZV9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family. DtpA subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Proton-dependent permease that transports di- and tripeptides.

2494701:FY206 RS21040
gene id: 2494701:FY206_RS21040
uniprot id: A0A5C1C442
names: Function
names: Similarity
names: Subunit
messages: Catalyzes the ADP transfer from ATP to D-glycero-beta-D-manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose.
messages: Catalyzes the phosphorylation of D-glycero-D-manno-heptose 7-phosphate at the C-1 position to selectively form D-glycero-beta-D-manno-heptose-1,7-bisphosphate.
messages: Homodimer.
messages: In the C-terminal section; belongs to the cytidylyltransferase family.
messages: In the N-terminal section; belongs to the carbohydrate kinase PfkB family.

2494701:FY206 RS08840
gene id: 2494701:FY206_RS08840
uniprot id: A0A5C1BZ78
names: Similarity
messages: Belongs to the UPF0434 family.

2494701:FY206 RS08570
gene id: 2494701:FY206_RS08570
uniprot id: A0A5C1BYD6
names: Activity Regulation
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A peripheral cell membrane enzyme that catalyzes the oxidative decarboxylation of pyruvate to form acetate and CO(2). It channels electrons from the cytoplasm to the respiratory chain at the cell membrane via ubiquinone.
messages: Belongs to the TPP enzyme family.
messages: Binds 1 FAD per subunit.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Cell membrane
messages: Has 4 domains; the Pyr domain which binds the pyrimidine moiety of the thiamine pyrophosphate cofactor, the FAD-binding domain, the PP-binding domain which binds the pyrophosphate portion of thiamine pyrophosphate and the C-terminal membrane binding region. The C-terminus is held closely against the rest of the protein and covers the active site; during activation it unfolds from the rest of the protein and forms an amphipathic helix upon membrane binding, exposing the active site.
messages: Homotetramer.
messages: The C-terminus inhibits activity; it has to move for the enzyme to be active. Activated by lipid-binding, which occurs via the C-terminus.

2494701:FY206 RS17275
gene id: 2494701:FY206_RS17275
uniprot id: A0A5C1C6R5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

2494701:FY206 RS21940
gene id: 2494701:FY206_RS21940
uniprot id: A0A5C1C4J6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

2494701:FY206 RS19890
gene id: 2494701:FY206_RS19890
uniprot id: A0A5C1C830
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.

2494701:FY206 RS01845
gene id: 2494701:FY206_RS01845
uniprot id: A0A5C1BUY9
names: Function
names: Similarity
messages: Belongs to the PhnJ family.
messages: Catalyzes the breakage of the C-P bond in alpha-D-ribose 1-methylphosphonate 5-phosphate (PRPn) forming alpha-D-ribose.

2494701:FY206 RS07240
gene id: 2494701:FY206_RS07240
uniprot id: A0A5C1BXJ0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2494701:FY206 RS21875
gene id: 2494701:FY206_RS21875
uniprot id: A0A5C1C5N8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptC family.
messages: Cell inner membrane
messages: Component of the lipopolysaccharide transport and assembly complex. Interacts with LptA and the LptBFG transporter complex.
messages: Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer of LPS from the inner membrane to the periplasmic protein LptA. Could be a docking site for LptA.
messages: Required for the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane.

2494701:FY206 RS23960
gene id: 2494701:FY206_RS23960
uniprot id: A0A5C1C6P9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

2494701:FY206 RS20640
gene id: 2494701:FY206_RS20640
uniprot id: A0A5C1C432
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-I family.

2494701:FY206 RS02765
gene id: 2494701:FY206_RS02765
uniprot id: A0A5C1BVD8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Cell inner membrane
messages: Membrane

2494701:FY206 RS04755
gene id: 2494701:FY206_RS04755
uniprot id: A0A5C1BWC1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

2494701:FY206 RS06990
gene id: 2494701:FY206_RS06990
uniprot id: A0A5C1BXG7
names: Function
messages: Repressor involved in choline regulation of the bet genes.
messages: Repressor involved in the biosynthesis of the osmoprotectant glycine betaine. It represses transcription of the choline transporter BetT and the genes of BetAB involved in the synthesis of glycine betaine.

2494701:FY206 RS01145
gene id: 2494701:FY206_RS01145
uniprot id: A0A5C1BUI0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

2494701:FY206 RS17985
gene id: 2494701:FY206_RS17985
uniprot id: A0A5C1C2P0
names: Subcellular Location Annotation
messages: Cytoplasm

2494701:FY206 RS11450
gene id: 2494701:FY206_RS11450
uniprot id: A0A5C1C0T6
names: Function
messages: Colicins are polypeptide toxins produced by and active against E.coli and closely related bacteria.

2494701:FY206 RS01165
gene id: 2494701:FY206_RS01165
uniprot id: A0A5C1BUZ0
names: Subcellular Location Annotation
messages: Membrane

2494701:FY206 RS07705
gene id: 2494701:FY206_RS07705
uniprot id: A0A5C1BXR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

2494701:FY206 RS00020
gene id: 2494701:FY206_RS00020
uniprot id: A0A5C1BUN0
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

2494701:FY206 RS06020
gene id: 2494701:FY206_RS06020
uniprot id: A0A5C1BWP8
names: Similarity
messages: Belongs to the UPF0178 family.

2494701:FY206 RS18465
gene id: 2494701:FY206_RS18465
uniprot id: A0A5C1C2Z8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RseB family.
messages: Periplasm

2494701:FY206 RS02920
gene id: 2494701:FY206_RS02920
uniprot id: A0A5C1BW81
names: Function
names: Similarity
messages: Belongs to the MurCDEF family. Mpl subfamily.
messages: Reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl-meso-diaminopimelate by linking it to UDP-N-acetylmuramate.

2494701:FY206 RS22195
gene id: 2494701:FY206_RS22195
uniprot id: A0A5C1C560
names: Function
names: Similarity
messages: Belongs to the Dus family. DusB subfamily.
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

2494701:FY206 RS10600
gene id: 2494701:FY206_RS10600
uniprot id: A0A5C1BZ66
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Vitamin B12 importer (TC 3.A.1.13.1) family.
messages: Cell membrane
messages: Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (BtuD), two transmembrane proteins (BtuC) and a solute-binding protein (BtuF).

2494701:FY206 RS09885
gene id: 2494701:FY206_RS09885
uniprot id: A0A5C1C028
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase E/G family. RNase E subfamily.
messages: Belongs to the RNase E/G family. RNase G subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per homotetramer.
messages: Cell inner membrane
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation. Within the RNA degradosome, RNase E assembles into a homotetramer formed by a dimer of dimers.
messages: Cytoplasm
messages: Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs.

2494701:FY206 RS19705
gene id: 2494701:FY206_RS19705
uniprot id: A0A5C1C4V6
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

2494701:FY206 RS02440
gene id: 2494701:FY206_RS02440
uniprot id: A0A5C1BUV6
names: Subcellular Location Annotation
messages: Membrane

2494701:FY206 RS03725
gene id: 2494701:FY206_RS03725
uniprot id: A0A5C1BVP1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methyltransferase superfamily. RsmC family.
messages: Cytoplasm
messages: Monomer.
messages: Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle.

2494701:FY206 RS23865
gene id: 2494701:FY206_RS23865
uniprot id: A0A5C1C5Y8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase M20A family. ArgE subfamily.
messages: Binds 2 Zn(2+) or Co(2+) ions per subunit.
messages: Catalyzes the hydrolysis of the amide bond of N(2)-acetylated L-amino acids. Cleaves the acetyl group from N-acetyl-L-ornithine to form L-ornithine, an intermediate in L-arginine biosynthesis pathway, and a branchpoint in the synthesis of polyamines.
messages: Cytoplasm
messages: Homodimer.

2494701:FY206 RS09455
gene id: 2494701:FY206_RS09455
uniprot id: A0A5C1BYE1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the oxidase-dependent Fe transporter (OFeT) (TC 9.A.10.1) family.
messages: Membrane
messages: Part of a ferrous iron transporter composed of EfeU, EfeO and EfeB.
messages: Uptake of Fe(2+) ions across the membrane.

2494701:FY206 RS19280
gene id: 2494701:FY206_RS19280
uniprot id: A0A5C1C3D6
names: Subcellular Location Annotation
messages: Membrane

2494701:FY206 RS08485
gene id: 2494701:FY206_RS08485
uniprot id: A0A5C1BXS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial secretin family. GSP D subfamily.
messages: Cell outer membrane
messages: Membrane

2494701:FY206 RS07045
gene id: 2494701:FY206_RS07045
uniprot id: A0A5C1BXS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Fes family.
messages: Cytoplasm

2494701:FY206 RS04455
gene id: 2494701:FY206_RS04455
uniprot id: A0A5C1BVV1
names: Similarity
messages: Belongs to the UPF0231 family.

2494701:FY206 RS10805
gene id: 2494701:FY206_RS10805
uniprot id: A0A5C1C0H3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YkuD family.
messages: Periplasm

2494701:FY206 RS00090
gene id: 2494701:FY206_RS00090
uniprot id: A0A5C1BTN3
names: Subcellular Location Annotation
messages: Membrane

2494701:FY206 RS06675
gene id: 2494701:FY206_RS06675
uniprot id: A0A5C1BX03
names: Subcellular Location Annotation
messages: Membrane

2494701:FY206 RS11945
gene id: 2494701:FY206_RS11945
uniprot id: A0A5C1C119
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
messages: Belongs to the azoreductase type 1 family.
messages: Binds 1 FMN per subunit.
messages: Homodimer.
messages: Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones.

2494701:FY206 RS03840
gene id: 2494701:FY206_RS03840
uniprot id: A0A5C1BVU7
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

2494701:FY206 RS05670
gene id: 2494701:FY206_RS05670
uniprot id: A0A5C1BWJ3
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Component of the dihydroxyacetone kinase complex, which is responsible for the phosphoenolpyruvate (PEP)-dependent phosphorylation of dihydroxyacetone. DhaM serves as the phosphoryl donor. Is phosphorylated by phosphoenolpyruvate in an EI- and HPr-dependent reaction, and a phosphorelay system on histidine residues finally leads to phosphoryl transfer to DhaL and dihydroxyacetone.

2494701:FY206 RS22625
gene id: 2494701:FY206_RS22625
uniprot id: A0A5C1C5C9
names: Function
names: Similarity
messages: Belongs to the CitG/MdcB family.
messages: Involved in the formation of 2-(5''-phosphoribosyl)-3'-dephosphocoenzyme-A, the prosthetic group of the acyl-carrier protein of the malonate decarboxylase.

2494701:FY206 RS16765
gene id: 2494701:FY206_RS16765
uniprot id: A0A5C1C2V2
names: Similarity
messages: Belongs to the elongation factor P family.

2494701:FY206 RS01140
gene id: 2494701:FY206_RS01140
uniprot id: A0A5C1BVC4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

2494701:FY206 RS18230
gene id: 2494701:FY206_RS18230
uniprot id: A0A5C1C3B1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

2494701:FY206 RS07215
gene id: 2494701:FY206_RS07215
uniprot id: A0A5C1BX92
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAD-like hydrolase superfamily. MasA/MtnC family.
messages: Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).
messages: Binds 1 Mg(2+) ion per subunit.
messages: Monomer.

2494701:FY206 RS06045
gene id: 2494701:FY206_RS06045
uniprot id: A0A5C1BWM7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RdgC family.
messages: May be involved in recombination.
messages: nucleoid

2494701:FY206 RS24090
gene id: 2494701:FY206_RS24090
uniprot id: A0A5C1C614
names: Function
names: Similarity
names: Subunit
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.
messages: Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.
messages: Homodimer.

2494701:FY206 RS16735
gene id: 2494701:FY206_RS16735
uniprot id: A0A5C1C2A1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AP endonuclease 2 family.
messages: Binds 3 Zn(2+) ions.
messages: Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.

2494701:FY206 RS08050
gene id: 2494701:FY206_RS08050
uniprot id: A0A5C1BXY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the periplasmic pilus chaperone family.
messages: Periplasm

2494701:FY206 RS01385
gene id: 2494701:FY206_RS01385
uniprot id: A0A5C1BV28
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UbiC family.
messages: Cytoplasm
messages: Monomer.
messages: Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway.

2494701:FY206 RS07410
gene id: 2494701:FY206_RS07410
uniprot id: A0A5C1BXZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

2494701:FY206 RS13805
gene id: 2494701:FY206_RS13805
uniprot id: A0A5C1C0Y5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

2494701:FY206 RS24210
gene id: 2494701:FY206_RS24210
uniprot id: A0A5C1C6T8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhE family.
messages: Cytoplasm
messages: Necessary for formate dehydrogenase activity.

2494701:FY206 RS17165
gene id: 2494701:FY206_RS17165
uniprot id: A0A5C1C2B3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2494701:FY206 RS01275
gene id: 2494701:FY206_RS01275
uniprot id: A0A5C1BU85
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AceK family.
messages: Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation.
messages: Cytoplasm

2494701:FY206 RS18985
gene id: 2494701:FY206_RS18985
uniprot id: A0A5C1C3G3
names: Similarity
messages: Belongs to the UPF0057 (PMP3) family.

2494701:FY206 RS23675
gene id: 2494701:FY206_RS23675
uniprot id: A0A5C1C5H4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.
messages: Catalyzes the reversible epimerization at C-2 of UDP-N-acetylglucosamine (UDP-GlcNAc) and thereby provides bacteria with UDP-N-acetylmannosamine (UDP-ManNAc), the activated donor of ManNAc residues.
messages: Cytoplasm
messages: Homodimer.

2494701:FY206 RS07750
gene id: 2494701:FY206_RS07750
uniprot id: A0A5C1BXU7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CpoB family.
messages: Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division.
messages: Periplasm

2494701:FY206 RS05910
gene id: 2494701:FY206_RS05910
uniprot id: A0A5C1BWX8
names: Subcellular Location Annotation
messages: Membrane

2494701:FY206 RS17140
gene id: 2494701:FY206_RS17140
uniprot id: A0A5C1C2N4
names: Function
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

2494701:FY206 RS15620
gene id: 2494701:FY206_RS15620
uniprot id: A0A5C1C2B0
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

2494701:FY206 RS25150
gene id: 2494701:FY206_RS25150
uniprot id: A0A5C1C923
names: Similarity
messages: Belongs to the peptidase A24 family.

2494701:FY206 RS19910
gene id: 2494701:FY206_RS19910
uniprot id: A0A5C1C3N0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the KduI family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of 5-dehydro-4-deoxy-D-glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate.

2494701:FY206 RS01620
gene id: 2494701:FY206_RS01620
uniprot id: A0A5C1BVL7
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

2494701:FY206 RS23585
gene id: 2494701:FY206_RS23585
uniprot id: A0A5C1C6J6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-1 family.
messages: Cytoplasm

2494701:FY206 RS22460
gene id: 2494701:FY206_RS22460
uniprot id: A0A5C1C6C5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

2494701:FY206 RS08880
gene id: 2494701:FY206_RS08880
uniprot id: A0A5C1BY78
names: Similarity
messages: Belongs to the YkuD family.

2494701:FY206 RS08520
gene id: 2494701:FY206_RS08520
uniprot id: A0A5C1BYC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP K family.
messages: Cell inner membrane
messages: Membrane

2494701:FY206 RS09800
gene id: 2494701:FY206_RS09800
uniprot id: A0A5C1BYV3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell inner membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Membrane

2494701:FY206 RS19320
gene id: 2494701:FY206_RS19320
uniprot id: A0A5C1C3D2
names: Similarity
messages: Belongs to the HypE family.

2494701:FY206 RS09810
gene id: 2494701:FY206_RS09810
uniprot id: A0A5C1BYZ0
names: Function
names: Similarity
messages: Belongs to the FlgM family.
messages: Responsible for the coupling of flagellin expression to flagellar assembly by preventing expression of the flagellin genes when a component of the middle class of proteins is defective. It negatively regulates flagellar genes by inhibiting the activity of FliA by directly binding to FliA.

2494701:FY206 RS23695
gene id: 2494701:FY206_RS23695
uniprot id: A0A5C1C739
names: Similarity
messages: Belongs to the thioredoxin family.

2494701:FY206 RS09610
gene id: 2494701:FY206_RS09610
uniprot id: A0A5C1BYJ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the YmdB family.
messages: Deacetylates O-acetyl-ADP ribose to yield ADP-ribose and free acetate. Down-regulates ribonuclease 3 (RNase III) activity. Acts by interacting directly with the region of the ribonuclease that is required for dimerization/activation.
messages: Homodimer. Interacts with RNase III.

2494701:FY206 RS06400
gene id: 2494701:FY206_RS06400
uniprot id: A0A5C1BX75
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

2494701:FY206 RS10305
gene id: 2494701:FY206_RS10305
uniprot id: A0A5C1BZA5
names: Function
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
messages: Catalyzes the oxidative phosphorylation of glyceraldehyde 3-phosphate (G3P) to 1,3-bisphosphoglycerate (BPG) using the cofactor NAD. The first reaction step involves the formation of a hemiacetal intermediate between G3P and a cysteine residue, and this hemiacetal intermediate is then oxidized to a thioester, with concomitant reduction of NAD to NADH. The reduced NADH is then exchanged with the second NAD, and the thioester is attacked by a nucleophilic inorganic phosphate to produce BPG.

2494701:FY206 RS17800
gene id: 2494701:FY206_RS17800
uniprot id: A0A5C1C3W1
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

2494701:FY206 RS06245
gene id: 2494701:FY206_RS06245
uniprot id: A0A5C1BWR1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Cell membrane
messages: Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron.
messages: Membrane

2494701:FY206 RS00220
gene id: 2494701:FY206_RS00220
uniprot id: A0A5C1BTI5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. DHA1 family. NepI (TC 2.A.1.2.26) subfamily.
messages: Cell inner membrane
messages: Involved in the efflux of purine ribonucleosides, such as inosine and guanosine.
messages: Membrane

2494701:FY206 RS13620
gene id: 2494701:FY206_RS13620
uniprot id: A0A5C1C0K4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the OMP decarboxylase family. Type 1 subfamily.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
messages: Homodimer.

2494701:FY206 RS21070
gene id: 2494701:FY206_RS21070
uniprot id: A0A5C1C490
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.
messages: Homooctamer.

2494701:FY206 RS08565
gene id: 2494701:FY206_RS08565
uniprot id: A0A5C1BYM3
names: Similarity
names: Subunit
messages: Belongs to the threonine aldolase family.
messages: Homotetramer.

2494701:FY206 RS00560
gene id: 2494701:FY206_RS00560
uniprot id: A0A5C1BU19
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.

2494701:FY206 RS24355
gene id: 2494701:FY206_RS24355
uniprot id: A0A5C1C5U5
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

2494701:FY206 RS01175
gene id: 2494701:FY206_RS01175
uniprot id: A0A5C1BU64
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

2494701:FY206 RS06080
gene id: 2494701:FY206_RS06080
uniprot id: A0A5C1BXA1
names: Subcellular Location Annotation
messages: Membrane

2494701:FY206 RS12585
gene id: 2494701:FY206_RS12585
uniprot id: A0A5C1C0F3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2494701:FY206 RS02445
gene id: 2494701:FY206_RS02445
uniprot id: A0A5C1BUT7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

2494701:FY206 RS24350
gene id: 2494701:FY206_RS24350
uniprot id: A0A5C1C662
names: Function
names: Similarity
names: Subunit
messages: A GTPase-activating protein (GAP) that modifies Der/EngA GTPase function. May play a role in ribosome biogenesis.
messages: Belongs to the YihI family.
messages: Interacts with Der.

2494701:FY206 RS21660
gene id: 2494701:FY206_RS21660
uniprot id: A0A5C1C4R7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase U32 family. UbiU subfamily.
messages: Forms an heterodimer with UbiV.
messages: Required for O(2)-independent ubiquinone (coenzyme Q) biosynthesis. Together with UbiV, is essential for the C6-hydroxylation reaction in the oxygen-independent ubiquinone biosynthesis pathway.

2494701:FY206 RS20425
gene id: 2494701:FY206_RS20425
uniprot id: A0A5C1C507
names: Similarity
messages: Belongs to the outer membrane porin (Opr) (TC 1.B.25) family.

2494701:FY206 RS22705
gene id: 2494701:FY206_RS22705
uniprot id: A0A5C1C5B6
names: Function
names: Similarity
messages: Belongs to the precorrin methyltransferase family.
messages: In the C-terminal section; belongs to the precorrin methyltransferase family.
messages: In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family.
messages: Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme.

2494701:FY206 RS16495
gene id: 2494701:FY206_RS16495
uniprot id: A0A5C1C1W8
names: Similarity
messages: Belongs to the group II decarboxylase family.

2494701:FY206 RS13655
gene id: 2494701:FY206_RS13655
uniprot id: A0A5C1C1T2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2494701:FY206 RS22920
gene id: 2494701:FY206_RS22920
uniprot id: A0A5C1C580
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
messages: Monomer.

2494701:FY206 RS01210
gene id: 2494701:FY206_RS01210
uniprot id: A0A5C1BUF8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2494701:FY206 RS23105
gene id: 2494701:FY206_RS23105
uniprot id: A0A5C1C5M0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

2494701:FY206 RS01905
gene id: 2494701:FY206_RS01905
uniprot id: A0A5C1BUL2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdgT transporter family.
messages: Catalyzes the proton-dependent uptake of 2-keto-3-deoxygluconate (KDG) into the cell.
messages: Cell membrane

2494701:FY206 RS22160
gene id: 2494701:FY206_RS22160
uniprot id: A0A5C1C6C3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

2494701:FY206 RS24260
gene id: 2494701:FY206_RS24260
uniprot id: A0A5C1C657
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0761 family.
messages: Cell membrane
messages: Membrane

2494701:FY206 RS15070
gene id: 2494701:FY206_RS15070
uniprot id: A0A5C1C225
names: Similarity
messages: Belongs to the peptidase C40 family.

2494701:FY206 RS06280
gene id: 2494701:FY206_RS06280
uniprot id: A0A5C1BXE3
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

2494701:FY206 RS18065
gene id: 2494701:FY206_RS18065
uniprot id: A0A5C1C341
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GppA/Ppx family.
messages: Cell membrane
messages: Membrane

2494701:FY206 RS21695
gene id: 2494701:FY206_RS21695
uniprot id: A0A5C1C4S8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

2494701:FY206 RS12895
gene id: 2494701:FY206_RS12895
uniprot id: A0A5C1C0K3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2494701:FY206 RS12855
gene id: 2494701:FY206_RS12855
uniprot id: A0A5C1C055
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2494701:FY206 RS07075
gene id: 2494701:FY206_RS07075
uniprot id: A0A5C1BYC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

2494701:FY206 RS17360
gene id: 2494701:FY206_RS17360
uniprot id: A0A5C1C3P8
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

2494701:FY206 RS19810
gene id: 2494701:FY206_RS19810
uniprot id: A0A5C1C593
names: Subcellular Location Annotation
messages: Membrane

2494701:FY206 RS17600
gene id: 2494701:FY206_RS17600
uniprot id: A0A5C1C3T4
names: Similarity
messages: Belongs to the ClpA/ClpB family.

2494701:FY206 RS20245
gene id: 2494701:FY206_RS20245
uniprot id: A0A5C1C480
names: Similarity
messages: Belongs to the RecJ family.

2494701:FY206 RS24430
gene id: 2494701:FY206_RS24430
uniprot id: A0A5C1C6X0
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

2494701:FY206 RS07455
gene id: 2494701:FY206_RS07455
uniprot id: A0A5C1BXM6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

2494701:FY206 RS04090
gene id: 2494701:FY206_RS04090
uniprot id: A0A5C1BVP3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

2494701:FY206 RS04955
gene id: 2494701:FY206_RS04955
uniprot id: A0A5C1BW40
names: Similarity
messages: Belongs to the transglycosylase Slt family.

2494701:FY206 RS05010
gene id: 2494701:FY206_RS05010
uniprot id: A0A5C1BWD0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

2494701:FY206 RS18285
gene id: 2494701:FY206_RS18285
uniprot id: A0A5C1C428
names: Function
names: Similarity
messages: Belongs to the heat shock protein 70 family.
messages: Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB. Involved in the maturation of IscU.

2494701:FY206 RS12995
gene id: 2494701:FY206_RS12995
uniprot id: A0A5C1C0E9
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20 family.
messages: Binds 2 Zn(2+) ions per subunit.

2494701:FY206 RS03485
gene id: 2494701:FY206_RS03485
uniprot id: A0A5C1BVD2
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

2494701:FY206 RS10820
gene id: 2494701:FY206_RS10820
uniprot id: A0A5C1C6M8
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

2494701:FY206 RS10260
gene id: 2494701:FY206_RS10260
uniprot id: A0A5C1BYU1
names: Subcellular Location Annotation
messages: Membrane

2494701:FY206 RS07875
gene id: 2494701:FY206_RS07875
uniprot id: A0A5C1BYQ3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-dependent hydrolases superfamily. HutI family.
messages: Binds 1 zinc or iron ion per subunit.
messages: Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate. It is the third step in the universal histidine degradation pathway.
messages: Cytoplasm

2494701:FY206 RS20625
gene id: 2494701:FY206_RS20625
uniprot id: A0A5C1C4D5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:citrate (SCF) symporter family.
messages: Cell membrane
messages: Uptake of citrate across the boundary membrane with the concomitant uptake of a sodium ion (symport system).

2494701:FY206 RS03515
gene id: 2494701:FY206_RS03515
uniprot id: A0A5C1BVE3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

2494701:FY206 RS01200
gene id: 2494701:FY206_RS01200
uniprot id: A0A5C1BU95
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Rsd/AlgQ family.
messages: Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase.
messages: Cytoplasm
messages: Interacts with RpoD.

2494701:FY206 RS11475
gene id: 2494701:FY206_RS11475
uniprot id: A0A5C1BZQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2494701:FY206 RS07280
gene id: 2494701:FY206_RS07280
uniprot id: A0A5C1BXL8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rnk family.
messages: Interacts with the RNA polymerase.
messages: May act as an anti-Gre factor.

2494701:FY206 RS08860
gene id: 2494701:FY206_RS08860
uniprot id: A0A5C1BYD8
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. CmoM family.
messages: Catalyzes the methylation of 5-carboxymethoxyuridine (cmo5U) to form 5-methoxycarbonylmethoxyuridine (mcmo5U) at position 34 in tRNAs.

2494701:FY206 RS04025
gene id: 2494701:FY206_RS04025
uniprot id: A0A5C1BWS3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

2494701:FY206 RS08865
gene id: 2494701:FY206_RS08865
uniprot id: A0A5C1BYS6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MukF family.
messages: Interacts, and probably forms a ternary complex, with MukE and MukB via its C-terminal region. The complex formation is stimulated by calcium or magnesium. It is required for an interaction between MukE and MukB.
messages: Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity.
messages: nucleoid

2494701:FY206 RS10860
gene id: 2494701:FY206_RS10860
uniprot id: A0A5C1C030
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

2494701:FY206 RS24455
gene id: 2494701:FY206_RS24455
uniprot id: A0A5C1C618
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAK/KUP transporter (TC 2.A.72) family.
messages: Cell membrane
messages: Membrane
messages: Responsible for the low-affinity transport of potassium into the cell, with the probable concomitant uptake of protons (symport system).

2494701:FY206 RS04190
gene id: 2494701:FY206_RS04190
uniprot id: A0A5C1BW42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Set transporter family.
messages: Membrane

2494701:FY206 RS16205
gene id: 2494701:FY206_RS16205
uniprot id: A0A5C1C351
names: Similarity
messages: Belongs to the UDPGP type 2 family.

2494701:FY206 RS07920
gene id: 2494701:FY206_RS07920
uniprot id: A0A5C1BXG5
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily.
messages: Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway.

2494701:FY206 RS16730
gene id: 2494701:FY206_RS16730
uniprot id: A0A5C1C2F4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0324 family.
messages: Membrane

2494701:FY206 RS17330
gene id: 2494701:FY206_RS17330
uniprot id: A0A5C1C363
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell inner membrane
messages: Membrane

2494701:FY206 RS11045
gene id: 2494701:FY206_RS11045
uniprot id: A0A5C1BZ84
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

2494701:FY206 RS10210
gene id: 2494701:FY206_RS10210
uniprot id: A0A5C1BYU0
names: Subcellular Location Annotation
messages: Membrane

2494701:FY206 RS08510
gene id: 2494701:FY206_RS08510
uniprot id: A0A5C1BY73
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GSP I family.
messages: Cell inner membrane
messages: Cleaved by prepilin peptidase.
messages: Component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm.
messages: Membrane
messages: Type II secretion is composed of four main components: the outer membrane complex, the inner membrane complex, the cytoplasmic secretion ATPase and the periplasm-spanning pseudopilus.

2494701:FY206 RS00915
gene id: 2494701:FY206_RS00915
uniprot id: A0A5C1BU34
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

2494701:FY206 RS17755
gene id: 2494701:FY206_RS17755
uniprot id: A0A5C1C2W1
names: Subcellular Location Annotation
messages: Membrane

2494701:FY206 RS15405
gene id: 2494701:FY206_RS15405
uniprot id: A0A5C1C1H7
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

2494701:FY206 RS16910
gene id: 2494701:FY206_RS16910
uniprot id: A0A5C1C259
names: Subcellular Location Annotation
messages: Membrane

2494701:FY206 RS13230
gene id: 2494701:FY206_RS13230
uniprot id: A0A5C1C171
names: Similarity
messages: Belongs to the bacterial solute-binding protein PotD/PotF family.

2494701:FY206 RS24045
gene id: 2494701:FY206_RS24045
uniprot id: A0A5C1C612
names: Subcellular Location Annotation
messages: Membrane

2494701:FY206 RS19840
gene id: 2494701:FY206_RS19840
uniprot id: A0A5C1C421
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MutH family.
messages: Cytoplasm
messages: Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair.

2494701:FY206 RS05105
gene id: 2494701:FY206_RS05105
uniprot id: A0A5C1BWU1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Gram-negative porin family.
messages: Cell outer membrane
messages: Homotrimer.
messages: Membrane

2494701:FY206 RS23445
gene id: 2494701:FY206_RS23445
uniprot id: A0A5C1C5K4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatB family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

2494701:FY206 RS10720
gene id: 2494701:FY206_RS10720
uniprot id: A0A5C1C680
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fimbrial export usher family.
messages: Cell outer membrane
messages: Membrane

2494701:FY206 RS00755
gene id: 2494701:FY206_RS00755
uniprot id: A0A5C1BV55
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lactate permease family.
messages: Cell inner membrane
messages: Membrane
messages: Uptake of L-lactate across the membrane. Can also transport D-lactate and glycolate.

2494701:FY206 RS03785
gene id: 2494701:FY206_RS03785
uniprot id: A0A5C1BW54
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
messages: Homodimer.
messages: The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis.

2494701:FY206 RS18225
gene id: 2494701:FY206_RS18225
uniprot id: A0A5C1C314
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.

2494701:FY206 RS22745
gene id: 2494701:FY206_RS22745
uniprot id: A0A5C1C5F3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial secretin family. PilQ subfamily.
messages: Cell outer membrane
messages: Membrane

2494701:FY206 RS22030
gene id: 2494701:FY206_RS22030
uniprot id: A0A5C1C4R1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AFG1 ATPase family. ZapE subfamily.
messages: Cytoplasm
messages: Interacts with FtsZ.
messages: Reduces the stability of FtsZ polymers in the presence of ATP.

2494701:FY206 RS09410
gene id: 2494701:FY206_RS09410
uniprot id: A0A5C1BYN9
names: Function
names: Similarity
messages: Belongs to the isochorismatase family. RutB subfamily.
messages: Hydrolyzes ureidoacrylate to form aminoacrylate and carbamate. The carbamate hydrolyzes spontaneously, thereby releasing one of the nitrogen atoms of the pyrimidine ring as ammonia and one of its carbon atoms as CO2.

2494701:FY206 RS17345
gene id: 2494701:FY206_RS17345
uniprot id: A0A5C1C2S1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. PdxB subfamily.
messages: Catalyzes the oxidation of erythronate-4-phosphate to 3-hydroxy-2-oxo-4-phosphonooxybutanoate.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2494701:FY206 RS23300
gene id: 2494701:FY206_RS23300
uniprot id: A0A5C1C5I4
names: Function
messages: Required for maximal bacterial cellulose synthesis.

2494701:FY206 RS22800
gene id: 2494701:FY206_RS22800
uniprot id: A0A5C1C659
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Cytoplasm
messages: Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
messages: Monomer.

2494701:FY206 RS03005
gene id: 2494701:FY206_RS03005
uniprot id: A0A5C1C717
names: Subcellular Location Annotation
messages: Membrane

2494701:FY206 RS19485
gene id: 2494701:FY206_RS19485
uniprot id: A0A5C1C3F1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2494701:FY206 RS18080
gene id: 2494701:FY206_RS18080
uniprot id: A0A5C1C385
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2494701:FY206 RS12960
gene id: 2494701:FY206_RS12960
uniprot id: A0A5C1C132
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2494701:FY206 RS03000
gene id: 2494701:FY206_RS03000
uniprot id: A0A5C1BVF7
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

2494701:FY206 RS22970
gene id: 2494701:FY206_RS22970
uniprot id: A0A5C1C589
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArnF family.
messages: Cell inner membrane
messages: Heterodimer of ArnE and ArnF.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Translocates 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane.

2494701:FY206 RS04800
gene id: 2494701:FY206_RS04800
uniprot id: A0A5C1BWP5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
messages: Cytoplasm
messages: Homotrimer.
messages: Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

2494701:FY206 RS07520
gene id: 2494701:FY206_RS07520
uniprot id: A0A5C1BX98
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Allosterically activated by N-acetylglucosamine 6-phosphate (GlcNAc6P).
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
messages: Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
messages: Homohexamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2494701:FY206 RS22590
gene id: 2494701:FY206_RS22590
uniprot id: A0A5C1C622
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2494701:FY206 RS01195
gene id: 2494701:FY206_RS01195
uniprot id: A0A5C1BUJ0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
messages: Homodimer.

2494701:FY206 RS20635
gene id: 2494701:FY206_RS20635
uniprot id: A0A5C1C494
names: Subcellular Location Annotation
messages: Cytoplasm

2494701:FY206 RS07625
gene id: 2494701:FY206_RS07625
uniprot id: A0A5C1BXB8
names: Similarity
messages: Belongs to the DNA photolyase class-1 family.
messages: Belongs to the DNA photolyase family.

2494701:FY206 RS06510
gene id: 2494701:FY206_RS06510
uniprot id: A0A5C1BWV3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

2494701:FY206 RS21635
gene id: 2494701:FY206_RS21635
uniprot id: A0A5C1C4W8
names: Similarity
messages: Belongs to the peptidase C56 family.

2494701:FY206 RS04000
gene id: 2494701:FY206_RS04000
uniprot id: A0A5C1BVX7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2494701:FY206 RS11440
gene id: 2494701:FY206_RS11440
uniprot id: A0A5C1BZD2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2494701:FY206 RS04865
gene id: 2494701:FY206_RS04865
uniprot id: A0A5C1BWA7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

2494701:FY206 RS24485
gene id: 2494701:FY206_RS24485
uniprot id: A0A5C1C6C0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

2494701:FY206 RS23215
gene id: 2494701:FY206_RS23215
uniprot id: A0A5C1C5K7
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

2494701:FY206 RS14400
gene id: 2494701:FY206_RS14400
uniprot id: A0A5C1C0V0
names: Subcellular Location Annotation
messages: Membrane

2494701:FY206 RS08445
gene id: 2494701:FY206_RS08445
uniprot id: A0A5C1BXV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

2494701:FY206 RS03340
gene id: 2494701:FY206_RS03340
uniprot id: A0A5C1BVH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

2494701:FY206 RS19315
gene id: 2494701:FY206_RS19315
uniprot id: A0A5C1C3E0
names: Similarity
messages: Belongs to the HypD family.

2494701:FY206 RS24950
gene id: 2494701:FY206_RS24950
uniprot id: A0A5C1C7Z5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the hok/gef family.
messages: Cell inner membrane

2494701:FY206 RS11155
gene id: 2494701:FY206_RS11155
uniprot id: A0A5C1BZJ5
names: Function
names: Similarity
messages: Belongs to the cytochrome b562 family.
messages: Electron-transport protein of unknown function.

2494701:FY206 RS06145
gene id: 2494701:FY206_RS06145
uniprot id: A0A5C1BWP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleoside-specific channel-forming outer membrane porin (Tsx) (TC 1.B.10) family.
messages: Cell outer membrane

2494701:FY206 RS16115
gene id: 2494701:FY206_RS16115
uniprot id: A0A5C1C1Q1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

2494701:FY206 RS23255
gene id: 2494701:FY206_RS23255
uniprot id: A0A5C1C6V9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2494701:FY206 RS11820
gene id: 2494701:FY206_RS11820
uniprot id: A0A5C1C032
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

2494701:FY206 RS06475
gene id: 2494701:FY206_RS06475
uniprot id: A0A5C1BWW6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

2494701:FY206 RS08630
gene id: 2494701:FY206_RS08630
uniprot id: A0A5C1BY32
names: Similarity
messages: Belongs to the ClpA/ClpB family.

2494701:FY206 RS16505
gene id: 2494701:FY206_RS16505
uniprot id: A0A5C1C2Q4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the etk/wzc family.
messages: Cell inner membrane
messages: Membrane

2494701:FY206 RS13895
gene id: 2494701:FY206_RS13895
uniprot id: A0A5C1C1H0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

2494701:FY206 RS23290
gene id: 2494701:FY206_RS23290
uniprot id: A0A5C1C5N0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Cell membrane
messages: Membrane
messages: Responsible for the transport of dicarboxylates such as succinate, fumarate, and malate across the membrane.

2494701:FY206 RS06070
gene id: 2494701:FY206_RS06070
uniprot id: A0A5C1BWQ6
names: Function
messages: Member of the two-component regulatory system PhoR/PhoB involved in the phosphate regulon genes expression. PhoR may function as a membrane-associated protein kinase that phosphorylates PhoB in response to environmental signals.

2494701:FY206 RS14365
gene id: 2494701:FY206_RS14365
uniprot id: A0A5C1C0U1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2494701:FY206 RS21550
gene id: 2494701:FY206_RS21550
uniprot id: A0A5C1C4C8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycyl radical enzyme (GRE) family. PFL subfamily.
messages: Cytoplasm
messages: Homodimer.

2494701:FY206 RS05055
gene id: 2494701:FY206_RS05055
uniprot id: A0A5C1BWT2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrC family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

2494701:FY206 RS09735
gene id: 2494701:FY206_RS09735
uniprot id: A0A5C1BYY2
names: Function
names: Similarity
messages: Belongs to the TrhO family.
messages: Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.

2494701:FY206 RS12985
gene id: 2494701:FY206_RS12985
uniprot id: A0A5C1C0G7
names: Similarity
messages: Belongs to the leucine-binding protein family.

2494701:FY206 RS17260
gene id: 2494701:FY206_RS17260
uniprot id: A0A5C1C2M8
names: Subunit
messages: Homooctamer.

2494701:FY206 RS08620
gene id: 2494701:FY206_RS08620
uniprot id: A0A5C1BYF3
names: Subcellular Location Annotation
messages: Cytoplasm

2494701:FY206 RS24645
gene id: 2494701:FY206_RS24645
uniprot id: A0A5C1C705
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

2494701:FY206 RS18200
gene id: 2494701:FY206_RS18200
uniprot id: A0A5C1C2T7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamB family.
messages: Cell outer membrane
messages: Part of the Bam complex, which is composed of the outer membrane protein BamA, and four lipoproteins BamB, BamC, BamD and BamE.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

2494701:FY206 RS04345
gene id: 2494701:FY206_RS04345
uniprot id: A0A5C1BVT1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA gyrase inhibitor YacG family.
messages: Binds 1 zinc ion.
messages: Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.
messages: Interacts with GyrB.

2494701:FY206 RS04305
gene id: 2494701:FY206_RS04305
uniprot id: A0A5C1BVU1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

2494701:FY206 RS19745
gene id: 2494701:FY206_RS19745
uniprot id: A0A5C1C3L0
names: Similarity
messages: Belongs to the SufE family.

2494701:FY206 RS05030
gene id: 2494701:FY206_RS05030
uniprot id: A0A5C1BXB7
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIS family. GmhA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
messages: Cytoplasm
messages: Homotetramer.
messages: The reaction produces a racemic mixture of D-glycero-alpha-D-manno-heptose 7-phosphate and D-glycero-beta-D-manno-heptose 7-phosphate.

2494701:FY206 RS22165
gene id: 2494701:FY206_RS22165
uniprot id: A0A5C1C674
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

2494701:FY206 RS15685
gene id: 2494701:FY206_RS15685
uniprot id: A0A5C1C1Y2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliR/MopE/SpaR family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

2494701:FY206 RS00320
gene id: 2494701:FY206_RS00320
uniprot id: A0A5C1BTL0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.
messages: Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU).
messages: Homotetramer.

2494701:FY206 RS07315
gene id: 2494701:FY206_RS07315
uniprot id: A0A5C1BXB2
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

2494701:FY206 RS08285
gene id: 2494701:FY206_RS08285
uniprot id: A0A5C1BYY3
names: Similarity
messages: Belongs to the GST superfamily.

2494701:FY206 RS08795
gene id: 2494701:FY206_RS08795
uniprot id: A0A5C1BYG4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.

2494701:FY206 RS23980
gene id: 2494701:FY206_RS23980
uniprot id: A0A5C1C744
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
messages: Belongs to the ClpX chaperone family. HslU subfamily.
messages: Cytoplasm

2494701:FY206 RS03975
gene id: 2494701:FY206_RS03975
uniprot id: A0A5C1BW07
names: Subcellular Location Annotation
messages: Membrane

2494701:FY206 RS19135
gene id: 2494701:FY206_RS19135
uniprot id: A0A5C1C3J9
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm
messages: Homotetramer.

2494701:FY206 RS18035
gene id: 2494701:FY206_RS18035
uniprot id: A0A5C1C304
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

2494701:FY206 RS03490
gene id: 2494701:FY206_RS03490
uniprot id: A0A5C1BVC0
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

2494701:FY206 RS19595
gene id: 2494701:FY206_RS19595
uniprot id: A0A5C1C4U1
names: Function
names: Similarity
messages: Belongs to the NanE family.
messages: Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P).

2494701:FY206 RS17310
gene id: 2494701:FY206_RS17310
uniprot id: A0A5C1C3P0
names: Subcellular Location Annotation
messages: Membrane

2494701:FY206 RS01665
gene id: 2494701:FY206_RS01665
uniprot id: A0A5C1BUE8
names: Similarity
messages: Belongs to the GST superfamily.

2494701:FY206 RS03060
gene id: 2494701:FY206_RS03060
uniprot id: A0A5C1BVG8
names: Subcellular Location Annotation
messages: Membrane

2494701:FY206 RS23685
gene id: 2494701:FY206_RS23685
uniprot id: A0A5C1C5P2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. WecA subfamily.
messages: Catalyzes the transfer of the GlcNAc-1-phosphate moiety from UDP-GlcNAc onto the carrier lipid undecaprenyl phosphate (C55-P), yielding GlcNAc-pyrophosphoryl-undecaprenyl (GlcNAc-PP-C55).
messages: Cell inner membrane
messages: Membrane

2494701:FY206 RS02590
gene id: 2494701:FY206_RS02590
uniprot id: A0A5C1BV82
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

2494701:FY206 RS07445
gene id: 2494701:FY206_RS07445
uniprot id: A0A5C1BXP9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

2494701:FY206 RS15675
gene id: 2494701:FY206_RS15675
uniprot id: A0A5C1C2W2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliP/MopC/SpaP family.
messages: Cell membrane
messages: Membrane
messages: Plays a role in the flagellum-specific transport system.

2494701:FY206 RS12900
gene id: 2494701:FY206_RS12900
uniprot id: A0A5C1C033
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2494701:FY206 RS06785
gene id: 2494701:FY206_RS06785
uniprot id: A0A5C1BY70
names: Subcellular Location Annotation
messages: Membrane

2494701:FY206 RS22520
gene id: 2494701:FY206_RS22520
uniprot id: A0A5C1C576
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

2494701:FY206 RS21125
gene id: 2494701:FY206_RS21125
uniprot id: A0A5C1C4A1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UreF family.
messages: Cytoplasm
messages: Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
messages: UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

2494701:FY206 RS06635
gene id: 2494701:FY206_RS06635
uniprot id: A0A5C1BX90
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SelU family.
messages: Involved in the post-transcriptional modification of the uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Catalyzes the conversion of 2-thiouridine (S2U-RNA) to 2-selenouridine (Se2U-RNA). Acts in a two-step process involving geranylation of 2-thiouridine (S2U) to S-geranyl-2-thiouridine (geS2U) and subsequent selenation of the latter derivative to 2-selenouridine (Se2U) in the tRNA chain.
messages: Monomer.

2494701:FY206 RS11660
gene id: 2494701:FY206_RS11660
uniprot id: A0A5C1C009
names: Subcellular Location Annotation
messages: Membrane

2494701:FY206 RS13815
gene id: 2494701:FY206_RS13815
uniprot id: A0A5C1C158
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

2494701:FY206 RS21000
gene id: 2494701:FY206_RS21000
uniprot id: A0A5C1C4H0
names: Similarity
messages: Belongs to the DODA-type extradiol aromatic ring-opening dioxygenase family.

2494701:FY206 RS13585
gene id: 2494701:FY206_RS13585
uniprot id: A0A5C1C0V3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNR ribonuclease family. RNase II subfamily.
messages: Cytoplasm
messages: Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction.

2494701:FY206 RS20190
gene id: 2494701:FY206_RS20190
uniprot id: A0A5C1C471
names: Similarity
messages: Belongs to the site-specific recombinase resolvase family.

2494701:FY206 RS01185
gene id: 2494701:FY206_RS01185
uniprot id: A0A5C1BU88
names: Cofactor
messages: Binds 1 zinc ion per subunit.

2494701:FY206 RS16050
gene id: 2494701:FY206_RS16050
uniprot id: A0A5C1C1N3
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

2494701:FY206 RS21615
gene id: 2494701:FY206_RS21615
uniprot id: A0A5C1C4D7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SIS family. DiaA subfamily.
messages: Homotetramer; dimer of dimers.
messages: Required for the timely initiation of chromosomal replication via direct interactions with the DnaA initiator protein.

2494701:FY206 RS11425
gene id: 2494701:FY206_RS11425
uniprot id: A0A5C1BZP9
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

2494701:FY206 RS22940
gene id: 2494701:FY206_RS22940
uniprot id: A0A5C1C5F2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sulfur carrier protein TusA family.
messages: Cytoplasm
messages: Interacts with IscS.
messages: Sulfur carrier protein involved in sulfur trafficking in the cell. Part of a sulfur-relay system required for 2-thiolation during synthesis of 2-thiouridine of the modified wobble base 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) in tRNA. Interacts with IscS and stimulates its cysteine desulfurase activity. Accepts an activated sulfur from IscS, which is then transferred to TusD, and thus determines the direction of sulfur flow from IscS to 2-thiouridine formation. Also appears to be involved in sulfur transfer for the biosynthesis of molybdopterin.

2494701:FY206 RS04945
gene id: 2494701:FY206_RS04945
uniprot id: A0A5C1C631
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0294 family.
messages: Cytoplasm

2494701:FY206 RS10795
gene id: 2494701:FY206_RS10795
uniprot id: A0A5C1BZ33
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
messages: Cysteine desulfurases mobilize the sulfur from L-cysteine to yield L-alanine, an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Component of the suf operon, which is activated and required under specific conditions such as oxidative stress and iron limitation. Acts as a potent selenocysteine lyase in vitro, that mobilizes selenium from L-selenocysteine. Selenocysteine lyase activity is however unsure in vivo.
messages: Cytoplasm
messages: Homodimer. Interacts with SufE and the SufBCD complex composed of SufB, SufC and SufD. The interaction with SufE is required to mediate the direct transfer of the sulfur atom from the S-sulfanylcysteine.

2494701:FY206 RS12520
gene id: 2494701:FY206_RS12520
uniprot id: A0A5C1C070
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2494701:FY206 RS13840
gene id: 2494701:FY206_RS13840
uniprot id: A0A5C1C1G2
names: Function
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.
messages: Catalyzes the hydrolysis of the thioester bond in palmitoyl-CoA and malonyl-CoA.

2494701:FY206 RS22400
gene id: 2494701:FY206_RS22400
uniprot id: A0A5C1C4T1
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

2494701:FY206 RS19245
gene id: 2494701:FY206_RS19245
uniprot id: A0A5C1C3T9
names: Subcellular Location Annotation
messages: Membrane

2494701:FY206 RS04685
gene id: 2494701:FY206_RS04685
uniprot id: A0A5C1BW12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

2494701:FY206 RS06060
gene id: 2494701:FY206_RS06060
uniprot id: A0A5C1BX04
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

2494701:FY206 RS11030
gene id: 2494701:FY206_RS11030
uniprot id: A0A5C1BZ67
names: Function
names: Similarity
messages: Belongs to the anhydro-N-acetylmuramic acid kinase family.
messages: Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.

2494701:FY206 RS09295
gene id: 2494701:FY206_RS09295
uniprot id: A0A5C1BYA9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2494701:FY206 RS06855
gene id: 2494701:FY206_RS06855
uniprot id: A0A5C1BXC2
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.
messages: Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.
messages: Homodimer.

2494701:FY206 RS16645
gene id: 2494701:FY206_RS16645
uniprot id: A0A5C1C2B6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0299 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

2494701:FY206 RS21810
gene id: 2494701:FY206_RS21810
uniprot id: A0A5C1C4U6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

2494701:FY206 RS21720
gene id: 2494701:FY206_RS21720
uniprot id: A0A5C1C4F9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

2494701:FY206 RS19585
gene id: 2494701:FY206_RS19585
uniprot id: A0A5C1C3I3
names: Cofactor
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.

2494701:FY206 RS14135
gene id: 2494701:FY206_RS14135
uniprot id: A0A5C1C107
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

2494701:FY206 RS23640
gene id: 2494701:FY206_RS23640
uniprot id: A0A5C1C727
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 26 family.
messages: Catalyzes the synthesis of Und-PP-GlcNAc-ManNAcA (Lipid II), the second lipid-linked intermediate involved in enterobacterial common antigen (ECA) synthesis.

2494701:FY206 RS21585
gene id: 2494701:FY206_RS21585
uniprot id: A0A5C1C4R0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HpcH/HpaI aldolase family. KDGluc aldolase subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible retro-aldol cleavage of both 5-keto-4-deoxy-D-glucarate and 2-keto-3-deoxy-D-glucarate to pyruvate and tartronic semialdehyde.
messages: Homohexamer; trimer of dimers.

2494701:FY206 RS10090
gene id: 2494701:FY206_RS10090
uniprot id: A0A5C1BZ38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

2494701:FY206 RS24155
gene id: 2494701:FY206_RS24155
uniprot id: A0A5C1C639
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

2494701:FY206 RS22475
gene id: 2494701:FY206_RS22475
uniprot id: A0A5C1C4Y5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

2494701:FY206 RS04750
gene id: 2494701:FY206_RS04750
uniprot id: A0A5C1BWN3
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by GTP. Inhibited by UTP.
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2494701:FY206 RS12450
gene id: 2494701:FY206_RS12450
uniprot id: A0A5C1C079
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0187 family.
messages: Membrane

2494701:FY206 RS10255
gene id: 2494701:FY206_RS10255
uniprot id: A0A5C1BZ95
names: Similarity
messages: Belongs to the CTP synthase family.

2494701:FY206 RS10690
gene id: 2494701:FY206_RS10690
uniprot id: A0A5C1C010
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thioesterase PaaI family.
messages: Catalyzes the hydrolysis of 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA) to 1,4-dihydroxy-2-naphthoate (DHNA).
messages: Homotetramer. Dimer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2494701:FY206 RS07815
gene id: 2494701:FY206_RS07815
uniprot id: A0A5C1BXM1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. GalK subfamily.
messages: Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2494701:FY206 RS15540
gene id: 2494701:FY206_RS15540
uniprot id: A0A5C1C2S7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ACC deaminase/D-cysteine desulfhydrase family.
messages: Catalyzes the alpha,beta-elimination reaction of D-cysteine and of several D-cysteine derivatives. It could be a defense mechanism against D-cysteine.
messages: Homodimer.

2494701:FY206 RS18240
gene id: 2494701:FY206_RS18240
uniprot id: A0A5C1C345
names: Function
names: Similarity
messages: Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family. Bacterial alpha-2-macroglobulin subfamily.
messages: Protects the bacterial cell from host peptidases.

2494701:FY206 RS24865
gene id: 2494701:FY206_RS24865
uniprot id: A0A5C1C6R7
names: Similarity
messages: Belongs to the peptidase S24 family.

2494701:FY206 RS24140
gene id: 2494701:FY206_RS24140
uniprot id: A0A5C1C624
names: Similarity
messages: Belongs to the glycosyl hydrolase.

2494701:FY206 RS20430
gene id: 2494701:FY206_RS20430
uniprot id: A0A5C1C446
names: Function
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.
messages: Catalyzes the formation of putrescine from agmatine.

2494701:FY206 RS16550
gene id: 2494701:FY206_RS16550
uniprot id: A0A5C1C1Z0
names: Subcellular Location Annotation
messages: Membrane

2494701:FY206 RS12100
gene id: 2494701:FY206_RS12100
uniprot id: A0A5C1BZR3
names: Similarity
messages: Belongs to the bacterial PQQ dehydrogenase family.

2494701:FY206 RS21775
gene id: 2494701:FY206_RS21775
uniprot id: A0A5C1C5L8
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

2494701:FY206 RS02800
gene id: 2494701:FY206_RS02800
uniprot id: A0A5C1BV13
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inositol monophosphatase superfamily. CysQ family.
messages: Cell inner membrane
messages: Converts adenosine-3',5'-bisphosphate (PAP) to AMP.

2494701:FY206 RS01420
gene id: 2494701:FY206_RS01420
uniprot id: A0A5C1BUE0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

2494701:FY206 RS17760
gene id: 2494701:FY206_RS17760
uniprot id: A0A5C1C2K0
names: Function
names: Similarity
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.

2494701:FY206 RS16175
gene id: 2494701:FY206_RS16175
uniprot id: A0A5C1C348
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

2494701:FY206 RS12590
gene id: 2494701:FY206_RS12590
uniprot id: A0A5C1BZZ0
names: Subcellular Location Annotation
messages: Membrane

2494701:FY206 RS17315
gene id: 2494701:FY206_RS17315
uniprot id: A0A5C1C2N8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedD family.
messages: Cell inner membrane
messages: Non-essential cell division protein that could be required for efficient cell constriction.
messages: The SPOR domain binds septal peptidoglycans and is required to target DedD to the septal ring.

2494701:FY206 RS12420
gene id: 2494701:FY206_RS12420
uniprot id: A0A5C1BZW2
names: Similarity
names: Subunit
messages: Belongs to the glutaminase family.
messages: Homotetramer.

2494701:FY206 RS11065
gene id: 2494701:FY206_RS11065
uniprot id: A0A5C1BZI8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

2494701:FY206 RS15850
gene id: 2494701:FY206_RS15850
uniprot id: A0A5C1C1T5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

2494701:FY206 RS14130
gene id: 2494701:FY206_RS14130
uniprot id: A0A5C1C174
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

2494701:FY206 RS23525
gene id: 2494701:FY206_RS23525
uniprot id: A0A5C1C5T4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phospholipase A1 family.
messages: Binds 1 Ca(2+) ion per monomer. In the dimeric form the Ca(2+) is bound by different amino acids with binding of each Ca(2+) shared with ligands coming from each monomer. The Ca(2+) ion may have a role in catalysis.
messages: Cell outer membrane
messages: Homodimer; dimerization is reversible, and the dimeric form is the active one.
messages: Hydrolysis of phosphatidylcholine with phospholipase A2 (EC 3.1.1.4) and phospholipase A1 (EC 3.1.1.32) activities.
messages: Membrane

2494701:FY206 RS02855
gene id: 2494701:FY206_RS02855
uniprot id: A0A5C1BV32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TamA family.
messages: Cell outer membrane
messages: Membrane

2494701:FY206 RS10565
gene id: 2494701:FY206_RS10565
uniprot id: A0A5C1BZF6
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

2494701:FY206 RS23900
gene id: 2494701:FY206_RS23900
uniprot id: A0A5C1C5L5
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

2494701:FY206 RS13365
gene id: 2494701:FY206_RS13365
uniprot id: A0A5C1C1N9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Cell inner membrane
messages: Membrane
messages: Zinc transporter. Acts as a Zn(2+):proton symporter, which likely mediates zinc ion uptake.

2494701:FY206 RS01135
gene id: 2494701:FY206_RS01135
uniprot id: A0A5C1BU77
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.
messages: Protein L10 is also a translational repressor protein. It controls the translation of the rplJL-rpoBC operon by binding to its mRNA.

2494701:FY206 RS23650
gene id: 2494701:FY206_RS23650
uniprot id: A0A5C1C5V0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 56 family.
messages: Catalyzes the synthesis of Und-PP-GlcNAc-ManNAcA-Fuc4NAc (Lipid III), the third lipid-linked intermediate involved in ECA synthesis.
messages: Cell inner membrane

2494701:FY206 RS21385
gene id: 2494701:FY206_RS21385
uniprot id: A0A5C1C4L5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial solute-binding protein 2 family.
messages: Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Binds AI-2 and delivers it to the LsrC and LsrD permeases.
messages: Periplasm
messages: The complex is composed of two ATP-binding proteins (LsrA), two transmembrane proteins (LsrC and LsrD) and a solute-binding protein (LsrB).

2494701:FY206 RS22790
gene id: 2494701:FY206_RS22790
uniprot id: A0A5C1C533
names: Similarity
messages: Belongs to the HSP15 family.

2494701:FY206 RS11555
gene id: 2494701:FY206_RS11555
uniprot id: A0A5C1BZH6
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

2494701:FY206 RS00475
gene id: 2494701:FY206_RS00475
uniprot id: A0A5C1BTP9
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

2494701:FY206 RS13640
gene id: 2494701:FY206_RS13640
uniprot id: A0A5C1C0V9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase II family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
messages: Homodimer.

2494701:FY206 RS10840
gene id: 2494701:FY206_RS10840
uniprot id: A0A5C1BZK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nlpA lipoprotein family.
messages: Membrane

2494701:FY206 RS21830
gene id: 2494701:FY206_RS21830
uniprot id: A0A5C1C4X4
names: Similarity
messages: Belongs to the BolA/IbaG family.

2494701:FY206 RS22170
gene id: 2494701:FY206_RS22170
uniprot id: A0A5C1C557
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

2494701:FY206 RS24135
gene id: 2494701:FY206_RS24135
uniprot id: A0A5C1C7E7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Oligosaccharide:H(+) symporter (OHS) (TC 2.A.1.5) family.
messages: Cell inner membrane
messages: Membrane

2494701:FY206 RS13905
gene id: 2494701:FY206_RS13905
uniprot id: A0A5C1C0L8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Membrane

2494701:FY206 RS17995
gene id: 2494701:FY206_RS17995
uniprot id: A0A5C1C4E7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

2494701:FY206 RS18845
gene id: 2494701:FY206_RS18845
uniprot id: A0A5C1C360
names: Similarity
messages: Belongs to the archaeal-type GPI family.

2494701:FY206 RS08030
gene id: 2494701:FY206_RS08030
uniprot id: A0A5C1BXZ8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the helicase family. DinG subfamily. Type 1 sub-subfamily.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA-dependent ATPase and 5'-3' DNA helicase.

2494701:FY206 RS01685
gene id: 2494701:FY206_RS01685
uniprot id: A0A5C1BUJ4
names: Subcellular Location Annotation
messages: Membrane

2494701:FY206 RS09210
gene id: 2494701:FY206_RS09210
uniprot id: A0A5C1BYN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

2494701:FY206 RS05040
gene id: 2494701:FY206_RS05040
uniprot id: A0A5C1BW80
names: Similarity
messages: Belongs to the YkuD family.

2494701:FY206 RS17205
gene id: 2494701:FY206_RS17205
uniprot id: A0A5C1C3M5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Homohexamer.
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the CobB/CobQ family.
messages: Involved in acetate metabolism.
messages: The N-terminal region seems to be important for proper quaternary structure. The C-terminal region contains the substrate-binding site.

2494701:FY206 RS16935
gene id: 2494701:FY206_RS16935
uniprot id: A0A5C1C2J0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

2494701:FY206 RS19885
gene id: 2494701:FY206_RS19885
uniprot id: A0A5C1C3Q6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2494701:FY206 RS03525
gene id: 2494701:FY206_RS03525
uniprot id: A0A5C1BWI7
names: Function
names: Similarity
messages: Belongs to the non-flavoprotein flavin reductase family. HpaC subfamily.
messages: Catalyzes the reduction of free flavins (FMN, FAD and riboflavin) by NADH. Subsequently, the reduced flavins diffuse to the large HpaB component or to other electron acceptors such as cytochrome c and Fe(3+) ion.

2494701:FY206 RS02795
gene id: 2494701:FY206_RS02795
uniprot id: A0A5C1BVC1
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

2494701:FY206 RS13555
gene id: 2494701:FY206_RS13555
uniprot id: A0A5C1C0V4
names: Subcellular Location Annotation
messages: Cell inner membrane

2494701:FY206 RS04045
gene id: 2494701:FY206_RS04045
uniprot id: A0A5C1BVW0
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

2494701:FY206 RS01595
gene id: 2494701:FY206_RS01595
uniprot id: A0A5C1BV62
names: Function
names: Similarity
messages: Belongs to the Dus family. DusA subfamily.
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs.

2494701:FY206 RS08495
gene id: 2494701:FY206_RS08495
uniprot id: A0A5C1BYB8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell inner membrane
messages: Component of the type II secretion system inner membrane complex required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm.
messages: Membrane

2494701:FY206 RS09830
gene id: 2494701:FY206_RS09830
uniprot id: A0A5C1BZN2
names: Function
names: Similarity
messages: Belongs to the FlgD family.
messages: Required for flagellar hook formation. May act as a scaffolding protein.

2494701:FY206 RS07650
gene id: 2494701:FY206_RS07650
uniprot id: A0A5C1BXS1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized pyrimidines, such as thymine glycol, 5,6-dihydrouracil and 5,6-dihydrothymine. Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

2494701:FY206 RS09965
gene id: 2494701:FY206_RS09965
uniprot id: A0A5C1BZ18
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.

2494701:FY206 RS20960
gene id: 2494701:FY206_RS20960
uniprot id: A0A5C1C4I4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase class-III family.
messages: Binds 2 Fe(2+) ions per subunit.
messages: Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes.

2494701:FY206 RS04725
gene id: 2494701:FY206_RS04725
uniprot id: A0A5C1BX69
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family.
messages: Cytoplasm
messages: Homotrimer.

2494701:FY206 RS17040
gene id: 2494701:FY206_RS17040
uniprot id: A0A5C1C2L4
names: Similarity
messages: Belongs to the CinA family.

2494701:FY206 RS08195
gene id: 2494701:FY206_RS08195
uniprot id: A0A5C1BXZ9
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

2494701:FY206 RS20730
gene id: 2494701:FY206_RS20730
uniprot id: A0A5C1C5P5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbD/TolR family.
messages: Cell inner membrane
messages: Cell membrane
messages: Involved in the TonB-dependent energy-dependent transport of various receptor-bound substrates.
messages: Membrane
messages: The accessory proteins ExbB and ExbD seem to form a complex with TonB.

2494701:FY206 RS10110
gene id: 2494701:FY206_RS10110
uniprot id: A0A5C1BZR9
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 2 residues (Tyr-92 and Arg-95) present in a large hydrophobic pocket are probably involved in substrate specificity. They are important for desuccinylation activity, but dispensable for deacetylation activity.
messages: Belongs to the sirtuin family. Class III subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-dependent lysine deacetylase that specifically removes acetyl groups on target proteins. Also acts as a protein-lysine deacylase by mediating protein desuccinylation and de-2-hydroxyisobutyrylation. Modulates the activities of several proteins which are inactive in their acylated form.

2494701:FY206 RS22710
gene id: 2494701:FY206_RS22710
uniprot id: A0A5C1C4Z3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.

2494701:FY206 RS13810
gene id: 2494701:FY206_RS13810
uniprot id: A0A5C1C0V1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0394 family.
messages: Membrane

2494701:FY206 RS18505
gene id: 2494701:FY206_RS18505
uniprot id: A0A5C1C2Z7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

2494701:FY206 RS23910
gene id: 2494701:FY206_RS23910
uniprot id: A0A5C1C6P3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transaldolase family. Type 3A subfamily.
messages: Catalyzes the reversible formation of fructose 6-phosphate from dihydroxyacetone and D-glyceraldehyde 3-phosphate via an aldolization reaction.
messages: Cytoplasm
messages: Homodecamer.

2494701:FY206 RS23455
gene id: 2494701:FY206_RS23455
uniprot id: A0A5C1C700
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC1 family. UbiB subfamily.
messages: Cell membrane
messages: Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2494701:FY206 RS11005
gene id: 2494701:FY206_RS11005
uniprot id: A0A5C1C6F2
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

2494701:FY206 RS04170
gene id: 2494701:FY206_RS04170
uniprot id: A0A5C1BVV2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: The complex is composed of two ATP-binding proteins (ThiQ), two transmembrane proteins (ThiP) and a solute-binding protein (ThiB).

2494701:FY206 RS09900
gene id: 2494701:FY206_RS09900
uniprot id: A0A5C1BYU6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YceF subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes 7-methyl-GTP (m(7)GTP). May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

2494701:FY206 RS09360
gene id: 2494701:FY206_RS09360
uniprot id: A0A5C1BYM6
names: Cofactor
names: Similarity
messages: Belongs to the WrbA family.
messages: Binds 1 FMN per monomer.

2494701:FY206 RS10465
gene id: 2494701:FY206_RS10465
uniprot id: A0A5C1BYY9
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane.

2494701:FY206 RS18350
gene id: 2494701:FY206_RS18350
uniprot id: A0A5C1C2W8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.

2494701:FY206 RS10815
gene id: 2494701:FY206_RS10815
uniprot id: A0A5C1BZ99
names: Similarity
messages: Belongs to the pyruvate kinase family.

2494701:FY206 RS00275
gene id: 2494701:FY206_RS00275
uniprot id: A0A5C1BTQ5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

2494701:FY206 RS16795
gene id: 2494701:FY206_RS16795
uniprot id: A0A5C1C3G5
names: Subcellular Location Annotation
messages: Membrane

2494701:FY206 RS04960
gene id: 2494701:FY206_RS04960
uniprot id: A0A5C1BW36
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Monomer.
messages: Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.

2494701:FY206 RS06055
gene id: 2494701:FY206_RS06055
uniprot id: A0A5C1BXT1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SMC family. SbcC subfamily.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

2494701:FY206 RS05070
gene id: 2494701:FY206_RS05070
uniprot id: A0A5C1BW64
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrF family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway.

2494701:FY206 RS02425
gene id: 2494701:FY206_RS02425
uniprot id: A0A5C1BUU8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DcuA/DcuB transporter (TC 2.A.13.1) family.
messages: Cell inner membrane
messages: Membrane
messages: Responsible for the transport of C4-dicarboxylates.

2494701:FY206 RS17195
gene id: 2494701:FY206_RS17195
uniprot id: A0A5C1C2I6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0208 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

2494701:FY206 RS21400
gene id: 2494701:FY206_RS21400
uniprot id: A0A5C1C6P2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. AI-2 autoinducer porter (TC 3.A.1.2.8) family.
messages: Cell inner membrane
messages: Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (LsrA), two transmembrane proteins (LsrC and LsrD) and a solute-binding protein (LsrB).

2494701:FY206 RS01475
gene id: 2494701:FY206_RS01475
uniprot id: A0A5C1BUF0
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

2494701:FY206 RS01435
gene id: 2494701:FY206_RS01435
uniprot id: A0A5C1BV37
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoH subfamily.
messages: Cytoplasm
messages: Interacts with the RNA polymerase core enzyme.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes.

2494701:FY206 RS01305
gene id: 2494701:FY206_RS01305
uniprot id: A0A5C1BUB3
names: Similarity
names: Subunit
messages: Belongs to the pseudouridine synthase RsuA family.
messages: Monomer.

2494701:FY206 RS13000
gene id: 2494701:FY206_RS13000
uniprot id: A0A5C1C0M1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAK/KUP transporter (TC 2.A.72) family.
messages: Cell membrane
messages: Membrane
messages: Responsible for the low-affinity transport of potassium into the cell, with the probable concomitant uptake of protons (symport system).

2494701:FY206 RS06355
gene id: 2494701:FY206_RS06355
uniprot id: A0A5C1BWS4
names: Subcellular Location Annotation
messages: Membrane

2494701:FY206 RS10950
gene id: 2494701:FY206_RS10950
uniprot id: A0A5C1BZU3
names: Similarity
messages: Belongs to the peptidase C40 family.

2494701:FY206 RS21980
gene id: 2494701:FY206_RS21980
uniprot id: A0A5C1C522
names: Similarity
messages: Belongs to the glutamate synthase family.

2494701:FY206 RS24315
gene id: 2494701:FY206_RS24315
uniprot id: A0A5C1C6V1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

2494701:FY206 RS23470
gene id: 2494701:FY206_RS23470
uniprot id: A0A5C1C5E6
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

2494701:FY206 RS03390
gene id: 2494701:FY206_RS03390
uniprot id: A0A5C1BVI1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

2494701:FY206 RS11760
gene id: 2494701:FY206_RS11760
uniprot id: A0A5C1C053
names: Function
names: Similarity
messages: Belongs to the phenylacetyl-CoA ligase family.
messages: Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).

2494701:FY206 RS01315
gene id: 2494701:FY206_RS01315
uniprot id: A0A5C1BUL3
names: Subcellular Location Annotation
messages: Membrane

2494701:FY206 RS07435
gene id: 2494701:FY206_RS07435
uniprot id: A0A5C1BYK3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell membrane
messages: Membrane

2494701:FY206 RS10850
gene id: 2494701:FY206_RS10850
uniprot id: A0A5C1BZ41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

2494701:FY206 RS21745
gene id: 2494701:FY206_RS21745
uniprot id: A0A5C1C5Z3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

2494701:FY206 RS23860
gene id: 2494701:FY206_RS23860
uniprot id: A0A5C1C6N4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

2494701:FY206 RS04785
gene id: 2494701:FY206_RS04785
uniprot id: A0A5C1BW34
names: Similarity
messages: Belongs to the skp family.

2494701:FY206 RS01455
gene id: 2494701:FY206_RS01455
uniprot id: A0A5C1BUE3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PanZ/PanM family.
messages: Controls both the activation and catalytic activity of PanD in a coenzyme A (CoA)-dependent fashion.
messages: Interacts with PanD in the presence of CoA.

2494701:FY206 RS14810
gene id: 2494701:FY206_RS14810
uniprot id: A0A5C1C1P0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type III secretion exporter family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

2494701:FY206 RS19045
gene id: 2494701:FY206_RS19045
uniprot id: A0A5C1C389
names: Similarity
messages: Belongs to the ABC transporter superfamily.

2494701:FY206 RS19530
gene id: 2494701:FY206_RS19530
uniprot id: A0A5C1C3G9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Homodimer.

2494701:FY206 RS16845
gene id: 2494701:FY206_RS16845
uniprot id: A0A5C1C3H2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YejK family.
messages: nucleoid

2494701:FY206 RS07090
gene id: 2494701:FY206_RS07090
uniprot id: A0A5C1BXG1
names: Similarity
messages: Belongs to the isochorismate synthase family.

2494701:FY206 RS09200
gene id: 2494701:FY206_RS09200
uniprot id: A0A5C1BYK4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.
messages: Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU).
messages: Homotetramer.

2494701:FY206 RS15655
gene id: 2494701:FY206_RS15655
uniprot id: A0A5C1C1R9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell inner membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

2494701:FY206 RS03860
gene id: 2494701:FY206_RS03860
uniprot id: A0A5C1BWP3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2494701:FY206 RS22125
gene id: 2494701:FY206_RS22125
uniprot id: A0A5C1C515
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Cell inner membrane
messages: Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins.
messages: Membrane

2494701:FY206 RS12935
gene id: 2494701:FY206_RS12935
uniprot id: A0A5C1C0S4
names: Cofactor
names: Function
names: Subcellular Location Annotation
messages: Binds 4 [4Fe-4S] clusters per subunit.
messages: Membrane
messages: The beta chain is an electron transfer unit containing 4 cysteine clusters involved in the formation of iron-sulfur centers.

2494701:FY206 RS16060
gene id: 2494701:FY206_RS16060
uniprot id: A0A5C1C2H3
names: Subcellular Location Annotation
messages: Membrane

2494701:FY206 RS09620
gene id: 2494701:FY206_RS09620
uniprot id: A0A5C1BZJ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OpgD/OpgG family.
messages: Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs).
messages: Periplasm

2494701:FY206 RS03735
gene id: 2494701:FY206_RS03735
uniprot id: A0A5C1BVS6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acetylates the N-terminal alanine of ribosomal protein S18.
messages: Belongs to the acetyltransferase family. RimI subfamily.
messages: Cytoplasm

2494701:FY206 RS00555
gene id: 2494701:FY206_RS00555
uniprot id: A0A5C1BTR2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

2494701:FY206 RS10485
gene id: 2494701:FY206_RS10485
uniprot id: A0A5C1BZ48
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YdjC deacetylase family. ChbG subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the degradation of chitin. ChbG is essential for growth on the acetylated chitooligosaccharides chitobiose and chitotriose but is dispensable for growth on cellobiose and chitosan dimer, the deacetylated form of chitobiose. Deacetylation of chitobiose-6-P and chitotriose-6-P is necessary for both the activation of the chb promoter by the regulatory protein ChbR and the hydrolysis of phosphorylated beta-glucosides by the phospho-beta-glucosidase ChbF. Catalyzes the removal of only one acetyl group from chitobiose-6-P to yield monoacetylchitobiose-6-P, the inducer of ChbR and the substrate of ChbF.

2494701:FY206 RS24525
gene id: 2494701:FY206_RS24525
uniprot id: A0A5C1C698
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

2494701:FY206 RS07945
gene id: 2494701:FY206_RS07945
uniprot id: A0A5C1BXW9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gluconeogenesis factor family.
messages: Cytoplasm
messages: Required for morphogenesis under gluconeogenic growth conditions.

2494701:FY206 RS01120
gene id: 2494701:FY206_RS01120
uniprot id: A0A5C1BUK6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NusG family.
messages: Monomer. Interacts with the transcription termination factor Rho and with RNA polymerase.
messages: Participates in transcription elongation, termination and antitermination. In the absence of Rho, increases the rate of transcription elongation by the RNA polymerase (RNAP), probably by partially suppressing pausing. In the presence of Rho, modulates most Rho-dependent termination events by interacting with the RNAP to render the complex more susceptible to the termination activity of Rho. May be required to overcome a kinetic limitation of Rho to function at certain terminators. Also involved in ribosomal RNA transcriptional antitermination.

2494701:FY206 RS22495
gene id: 2494701:FY206_RS22495
uniprot id: A0A5C1C4V3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

2494701:FY206 RS05020
gene id: 2494701:FY206_RS05020
uniprot id: A0A5C1BW52
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

2494701:FY206 RS04810
gene id: 2494701:FY206_RS04810
uniprot id: A0A5C1BWA1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

2494701:FY206 RS09870
gene id: 2494701:FY206_RS09870
uniprot id: A0A5C1BYM5
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Secreted

2494701:FY206 RS23945
gene id: 2494701:FY206_RS23945
uniprot id: A0A5C1C5Z1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MetJ family.
messages: Cytoplasm
messages: Does not bind DNA by a helix-turn-helix motif.
messages: Homodimer.
messages: This regulatory protein, when combined with SAM (S-adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis.

2494701:FY206 RS07810
gene id: 2494701:FY206_RS07810
uniprot id: A0A5C1BXY0
names: Similarity
messages: Belongs to the aldose epimerase family.

2494701:FY206 RS15795
gene id: 2494701:FY206_RS15795
uniprot id: A0A5C1C206
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Metabolite:H+ Symporter (MHS) family (TC 2.A.1.6) family.
messages: Cell inner membrane
messages: Membrane

2494701:FY206 RS12035
gene id: 2494701:FY206_RS12035
uniprot id: A0A5C1BZQ3
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

2494701:FY206 RS19475
gene id: 2494701:FY206_RS19475
uniprot id: A0A5C1C3N2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UbiX/PAD1 family. YclB subfamily.
messages: Homododecamer.
messages: Involved in the non-oxidative decarboxylation and detoxification of phenolic derivatives. Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for phenolic acid decarboxylase.

2494701:FY206 RS22575
gene id: 2494701:FY206_RS22575
uniprot id: A0A5C1C586
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. KefB subfamily.
messages: Cell inner membrane
messages: Interacts with the regulatory subunit KefG.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pore-forming subunit of a potassium efflux system that confers protection against electrophiles. Catalyzes K(+)/H(+) antiport.

2494701:FY206 RS02325
gene id: 2494701:FY206_RS02325
uniprot id: A0A5C1BVH7
names: Similarity
messages: Belongs to the outer membrane porin (Opr) (TC 1.B.25) family.

2494701:FY206 RS02740
gene id: 2494701:FY206_RS02740
uniprot id: A0A5C1BVB0
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

2494701:FY206 RS19300
gene id: 2494701:FY206_RS19300
uniprot id: A0A5C1C4I3
names: Function
names: Similarity
messages: Belongs to the HypA/HybF family.
messages: Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.

2494701:FY206 RS17970
gene id: 2494701:FY206_RS17970
uniprot id: A0A5C1C373
names: Similarity
messages: Belongs to the SAICAR synthetase family.

2494701:FY206 RS23665
gene id: 2494701:FY206_RS23665
uniprot id: A0A5C1C6K6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the WecD family.
messages: Catalyzes the acetylation of dTDP-fucosamine (dTDP-4-amino-4,6-dideoxy-D-galactose) to dTDP-Fuc4NAc, which is utilized in the biosynthesis of the enterobacterial common antigen (ECA).
messages: Homodimer.

2494701:FY206 RS06360
gene id: 2494701:FY206_RS06360
uniprot id: A0A5C1BXZ5
names: Similarity
messages: Belongs to the P(II) protein family.

2494701:FY206 RS09430
gene id: 2494701:FY206_RS09430
uniprot id: A0A5C1BYW4
names: Function
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.
messages: In the C-terminal section; belongs to the aldehyde dehydrogenase family.
messages: In the N-terminal section; belongs to the proline dehydrogenase family.
messages: Oxidizes proline to glutamate for use as a carbon and nitrogen source.

2494701:FY206 RS09905
gene id: 2494701:FY206_RS09905
uniprot id: A0A5C1BYX3
names: Function
names: Similarity
messages: Belongs to the DUF177 domain family.
messages: Plays a role in synthesis, processing and/or stability of 23S rRNA.

2494701:FY206 RS12925
gene id: 2494701:FY206_RS12925
uniprot id: A0A5C1C0I9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.
messages: Homotetramer.
messages: Uses inorganic polyphosphate (polyP) as a donor to convert GDP to GTP or ADP to ATP.

2494701:FY206 RS08090
gene id: 2494701:FY206_RS08090
uniprot id: A0A5C1BXN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

2494701:FY206 RS13830
gene id: 2494701:FY206_RS13830
uniprot id: A0A5C1C0L0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0259 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

2494701:FY206 RS07960
gene id: 2494701:FY206_RS07960
uniprot id: A0A5C1BY11
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

2494701:FY206 RS14795
gene id: 2494701:FY206_RS14795
uniprot id: A0A5C1C126
names: Similarity
messages: Belongs to the sodium:galactoside symporter (TC 2.A.2) family.

2494701:FY206 RS05115
gene id: 2494701:FY206_RS05115
uniprot id: A0A5C1BWF0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

2494701:FY206 RS14630
gene id: 2494701:FY206_RS14630
uniprot id: A0A5C1C1U6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CopC family.
messages: Involved in copper resistance. Appears to be involved in copper uptake.
messages: Periplasm

2494701:FY206 RS17080
gene id: 2494701:FY206_RS17080
uniprot id: A0A5C1C3K3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ElaB/YgaM/YqjD family.
messages: Cell inner membrane
messages: Membrane

2494701:FY206 RS23770
gene id: 2494701:FY206_RS23770
uniprot id: A0A5C1C5W5
names: Function
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.
messages: Negatively regulates the transcription of the flagellar master operon flhDC by binding to the upstream region of the operon.

2494701:FY206 RS21510
gene id: 2494701:FY206_RS21510
uniprot id: A0A5C1C616
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

2494701:FY206 RS16255
gene id: 2494701:FY206_RS16255
uniprot id: A0A5C1C359
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. Fucose synthase subfamily.
messages: Catalyzes the two-step NADP-dependent conversion of GDP-4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction.

2494701:FY206 RS15595
gene id: 2494701:FY206_RS15595
uniprot id: A0A5C1C2T9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum
messages: Belongs to the FliD family.
messages: Homopentamer.
messages: Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
messages: Required for the morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
messages: Secreted

2494701:FY206 RS19700
gene id: 2494701:FY206_RS19700
uniprot id: A0A5C1C571
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

2494701:FY206 RS08735
gene id: 2494701:FY206_RS08735
uniprot id: A0A5C1BXX8
names: Function
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.
messages: DNA-dependent ATPase that plays important roles in cellular responses to stalled DNA replication processes.

2494701:FY206 RS22310
gene id: 2494701:FY206_RS22310
uniprot id: A0A5C1C693
names: Similarity
messages: Belongs to the Smg family.

2494701:FY206 RS21935
gene id: 2494701:FY206_RS21935
uniprot id: A0A5C1C4Z0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptF/LptG family.
messages: Cell inner membrane
messages: Component of the lipopolysaccharide transport and assembly complex. The LptBFG transporter is composed of two ATP-binding proteins (LptB) and two transmembrane proteins (LptF and LptG).
messages: Membrane
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane.