2490633:EHW89 RS01420
gene id: 2490633:EHW89_RS01420
uniprot id: A0A3Q9F2J6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

2490633:EHW89 RS06815
gene id: 2490633:EHW89_RS06815
uniprot id: A0A3S9MSP2
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

2490633:EHW89 RS02670
gene id: 2490633:EHW89_RS02670
uniprot id: A0A3Q9EXT9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

2490633:EHW89 RS05490
gene id: 2490633:EHW89_RS05490
uniprot id: A0A3Q9EYL5
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

2490633:EHW89 RS07200
gene id: 2490633:EHW89_RS07200
uniprot id: A0A3Q9EZ48
names: Similarity
messages: Belongs to the asparaginase 1 family.

2490633:EHW89 RS08430
gene id: 2490633:EHW89_RS08430
uniprot id: A0A3Q9F523
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

2490633:EHW89 RS02585
gene id: 2490633:EHW89_RS02585
uniprot id: A0A3S9MQF1
names: Similarity
messages: Belongs to the citrate synthase family.

2490633:EHW89 RS08065
gene id: 2490633:EHW89_RS08065
uniprot id: A0A3Q9F4G8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

2490633:EHW89 RS05280
gene id: 2490633:EHW89_RS05280
uniprot id: A0A3S9MRV2
names: Similarity
messages: Belongs to the ribF family.

2490633:EHW89 RS07550
gene id: 2490633:EHW89_RS07550
uniprot id: A0A3Q9F486
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

2490633:EHW89 RS07680
gene id: 2490633:EHW89_RS07680
uniprot id: A0A3Q9F3G5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

2490633:EHW89 RS03055
gene id: 2490633:EHW89_RS03055
uniprot id: A0A3Q9F2I4
names: Subcellular Location Annotation
messages: Membrane

2490633:EHW89 RS02255
gene id: 2490633:EHW89_RS02255
uniprot id: A0A3Q9EXS3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PPase class C family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm

2490633:EHW89 RS06175
gene id: 2490633:EHW89_RS06175
uniprot id: A0A3S9MSF1
names: Cofactor
messages: Binds 1 Mg(2+) ion per trimer.

2490633:EHW89 RS05930
gene id: 2490633:EHW89_RS05930
uniprot id: A0A3Q9F3R9
names: Similarity
messages: Belongs to the UPF0236 family.

2490633:EHW89 RS01180
gene id: 2490633:EHW89_RS01180
uniprot id: A0A3Q9F2H2
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

2490633:EHW89 RS08290
gene id: 2490633:EHW89_RS08290
uniprot id: A0A3S9MTC4
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

2490633:EHW89 RS05070
gene id: 2490633:EHW89_RS05070
uniprot id: A0A3Q9F420
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

2490633:EHW89 RS06530
gene id: 2490633:EHW89_RS06530
uniprot id: A0A3Q9F422
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

2490633:EHW89 RS07580
gene id: 2490633:EHW89_RS07580
uniprot id: A0A3Q9EZI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

2490633:EHW89 RS08390
gene id: 2490633:EHW89_RS08390
uniprot id: A0A3S9MTE7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

2490633:EHW89 RS04120
gene id: 2490633:EHW89_RS04120
uniprot id: A0A3S9MR72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

2490633:EHW89 RS07670
gene id: 2490633:EHW89_RS07670
uniprot id: A0A3Q9EZ99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

2490633:EHW89 RS00230
gene id: 2490633:EHW89_RS00230
uniprot id: A0A3S9MP67
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

2490633:EHW89 RS06235
gene id: 2490633:EHW89_RS06235
uniprot id: A0A3S9MSD4
names: Function
names: Similarity
messages: Belongs to the flavodoxin family.
messages: Low-potential electron donor to a number of redox enzymes.

2490633:EHW89 RS01115
gene id: 2490633:EHW89_RS01115
uniprot id: A0A3S9MPJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

2490633:EHW89 RS07335
gene id: 2490633:EHW89_RS07335
uniprot id: A0A3S9MSY7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RpoE family.
messages: Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling.
messages: RNAP is composed of a core of 2 alpha, a beta and a beta' subunits. The core is associated with a delta subunit and one of several sigma factors.

2490633:EHW89 RS01845
gene id: 2490633:EHW89_RS01845
uniprot id: A0A3S9MPY5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GpsB family.
messages: Cytoplasm
messages: Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation.
messages: Forms polymers through the coiled coil domains. Interacts with PBP1, MreC and EzrA.

2490633:EHW89 RS06320
gene id: 2490633:EHW89_RS06320
uniprot id: A0A3S9MSC3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HPr family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The phosphoryl group from phosphoenolpyruvate (PEP) is transferred to the phosphoryl carrier protein HPr by enzyme I. Phospho-HPr then transfers it to the PTS EIIA domain.
messages: P-Ser-HPr interacts with the catabolite control protein A (CcpA), forming a complex that binds to DNA at the catabolite response elements cre, operator sites preceding a large number of catabolite-regulated genes. Thus, P-Ser-HPr is a corepressor in carbon catabolite repression (CCR), a mechanism that allows bacteria to coordinate and optimize the utilization of available carbon sources. P-Ser-HPr also plays a role in inducer exclusion, in which it probably interacts with several non-PTS permeases and inhibits their transport activity.

2490633:EHW89 RS02390
gene id: 2490633:EHW89_RS02390
uniprot id: A0A3S9MQ84
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

2490633:EHW89 RS08680
gene id: 2490633:EHW89_RS08680
uniprot id: A0A3Q9F4J8
names: Function
names: Similarity
messages: Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Belongs to the organic radical-activating enzymes family.

2490633:EHW89 RS08360
gene id: 2490633:EHW89_RS08360
uniprot id: A0A3Q9F4H2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

2490633:EHW89 RS07500
gene id: 2490633:EHW89_RS07500
uniprot id: A0A3Q9EZI0
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

2490633:EHW89 RS01735
gene id: 2490633:EHW89_RS01735
uniprot id: A0A3S9MQA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

2490633:EHW89 RS02420
gene id: 2490633:EHW89_RS02420
uniprot id: A0A3S9MQA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

2490633:EHW89 RS03000
gene id: 2490633:EHW89_RS03000
uniprot id: A0A3S9MQJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

2490633:EHW89 RS06575
gene id: 2490633:EHW89_RS06575
uniprot id: A0A3Q9F4J4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

2490633:EHW89 RS04130
gene id: 2490633:EHW89_RS04130
uniprot id: A0A3Q9EY69
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

2490633:EHW89 RS06515
gene id: 2490633:EHW89_RS06515
uniprot id: A0A3Q9F356
names: Similarity
messages: Belongs to the Fur family.

2490633:EHW89 RS01840
gene id: 2490633:EHW89_RS01840
uniprot id: A0A3S9MQC7
names: Similarity
messages: Belongs to the UPF0398 family.

2490633:EHW89 RS02250
gene id: 2490633:EHW89_RS02250
uniprot id: A0A3S9MQB1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Belongs to the organic radical-activating enzymes family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm

2490633:EHW89 RS01250
gene id: 2490633:EHW89_RS01250
uniprot id: A0A3S9MPR7
names: Similarity
messages: Belongs to the DCK/DGK family.

2490633:EHW89 RS08950
gene id: 2490633:EHW89_RS08950
uniprot id: A0A3Q9F4M9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

2490633:EHW89 RS08385
gene id: 2490633:EHW89_RS08385
uniprot id: A0A3Q9EZF8
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

2490633:EHW89 RS08380
gene id: 2490633:EHW89_RS08380
uniprot id: A0A3Q9F4J9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

2490633:EHW89 RS02875
gene id: 2490633:EHW89_RS02875
uniprot id: A0A3Q9F3K0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

2490633:EHW89 RS04925
gene id: 2490633:EHW89_RS04925
uniprot id: A0A3Q9F3K2
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

2490633:EHW89 RS08880
gene id: 2490633:EHW89_RS08880
uniprot id: A0A3S9MTP9
names: Similarity
messages: Belongs to the HicA mRNA interferase family.

2490633:EHW89 RS01465
gene id: 2490633:EHW89_RS01465
uniprot id: A0A3Q9F1Y8
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Homodimer.
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II ManXYZ PTS system is involved in mannose transport.

2490633:EHW89 RS04155
gene id: 2490633:EHW89_RS04155
uniprot id: A0A3S9MR65
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A probable RNA chaperone. Forms a complex with KhpB which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm
messages: Forms a complex with KhpB.

2490633:EHW89 RS08405
gene id: 2490633:EHW89_RS08405
uniprot id: A0A3Q9F518
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

2490633:EHW89 RS02990
gene id: 2490633:EHW89_RS02990
uniprot id: A0A3S9MQL4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

2490633:EHW89 RS01235
gene id: 2490633:EHW89_RS01235
uniprot id: A0A3Q9F2Y4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

2490633:EHW89 RS06120
gene id: 2490633:EHW89_RS06120
uniprot id: A0A3Q9F3Z4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

2490633:EHW89 RS01010
gene id: 2490633:EHW89_RS01010
uniprot id: A0A3Q9EX80
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

2490633:EHW89 RS08375
gene id: 2490633:EHW89_RS08375
uniprot id: A0A3S9MTG1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

2490633:EHW89 RS07685
gene id: 2490633:EHW89_RS07685
uniprot id: A0A3S9MT45
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

2490633:EHW89 RS08750
gene id: 2490633:EHW89_RS08750
uniprot id: A0A3S9MTL1
names: Similarity
messages: Belongs to the ArsC family.

2490633:EHW89 RS08100
gene id: 2490633:EHW89_RS08100
uniprot id: A0A3Q9F3U7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

2490633:EHW89 RS08635
gene id: 2490633:EHW89_RS08635
uniprot id: A0A3Q9F535
names: Similarity
messages: Belongs to the stealth family.

2490633:EHW89 RS04070
gene id: 2490633:EHW89_RS04070
uniprot id: A0A3Q9EYI1
names: Similarity
messages: Belongs to the Nudix hydrolase family.

2490633:EHW89 RS05335
gene id: 2490633:EHW89_RS05335
uniprot id: A0A3S9MRW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

2490633:EHW89 RS08395
gene id: 2490633:EHW89_RS08395
uniprot id: A0A3Q9EZR3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

2490633:EHW89 RS04215
gene id: 2490633:EHW89_RS04215
uniprot id: A0A3S9MRB9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

2490633:EHW89 RS00420
gene id: 2490633:EHW89_RS00420
uniprot id: A0A3S9MPF0
names: Similarity
messages: In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
messages: In the N-terminal section; belongs to the aldehyde dehydrogenase family.

2490633:EHW89 RS06740
gene id: 2490633:EHW89_RS06740
uniprot id: A0A3S9MSN3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ScpA family.
messages: Component of a cohesin-like complex composed of ScpA, ScpB and the Smc homodimer, in which ScpA and ScpB bind to the head domain of Smc. The presence of the three proteins is required for the association of the complex with DNA.
messages: Cytoplasm
messages: Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves.

2490633:EHW89 RS03805
gene id: 2490633:EHW89_RS03805
uniprot id: A0A3S9MR79
names: Function
names: Similarity
messages: Belongs to the RapZ-like family.
messages: Displays ATPase and GTPase activities.

2490633:EHW89 RS08280
gene id: 2490633:EHW89_RS08280
uniprot id: A0A3S9MTE0
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

2490633:EHW89 RS00440
gene id: 2490633:EHW89_RS00440
uniprot id: A0A3Q9F1P9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

2490633:EHW89 RS02100
gene id: 2490633:EHW89_RS02100
uniprot id: A0A3Q9F3A1
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

2490633:EHW89 RS08425
gene id: 2490633:EHW89_RS08425
uniprot id: A0A3S9MTH6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

2490633:EHW89 RS07525
gene id: 2490633:EHW89_RS07525
uniprot id: A0A3Q9F4Z0
names: Similarity
messages: Belongs to the thioredoxin family.

2490633:EHW89 RS00515
gene id: 2490633:EHW89_RS00515
uniprot id: A0A3Q9F1R0
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit.

2490633:EHW89 RS08330
gene id: 2490633:EHW89_RS08330
uniprot id: A0A3Q9F514
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

2490633:EHW89 RS05545
gene id: 2490633:EHW89_RS05545
uniprot id: A0A3Q9F471
names: Similarity
messages: Belongs to the phosphohexose mutase family.

2490633:EHW89 RS06375
gene id: 2490633:EHW89_RS06375
uniprot id: A0A3S9MSD3
names: Similarity
messages: Belongs to the UPF0213 family.

2490633:EHW89 RS02170
gene id: 2490633:EHW89_RS02170
uniprot id: A0A3Q9F380
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

2490633:EHW89 RS06900
gene id: 2490633:EHW89_RS06900
uniprot id: A0A3S9MSR1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2490633:EHW89 RS02980
gene id: 2490633:EHW89_RS02980
uniprot id: A0A3Q9F298
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

2490633:EHW89 RS02965
gene id: 2490633:EHW89_RS02965
uniprot id: A0A3Q9F339
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

2490633:EHW89 RS09250
gene id: 2490633:EHW89_RS09250
uniprot id: A0A3Q9F4U3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane
messages: This protein catalyzes the committed step to the synthesis of the acidic phospholipids.

2490633:EHW89 RS03005
gene id: 2490633:EHW89_RS03005
uniprot id: A0A3Q9F333
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

2490633:EHW89 RS07945
gene id: 2490633:EHW89_RS07945
uniprot id: A0A3Q9F4G0
names: Similarity
messages: Belongs to the thioredoxin family.

2490633:EHW89 RS08725
gene id: 2490633:EHW89_RS08725
uniprot id: A0A3Q9F547
names: Similarity
messages: Belongs to the UPF0473 family.

2490633:EHW89 RS02175
gene id: 2490633:EHW89_RS02175
uniprot id: A0A3Q9F3B1
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

2490633:EHW89 RS08410
gene id: 2490633:EHW89_RS08410
uniprot id: A0A3S9MTE8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

2490633:EHW89 RS02600
gene id: 2490633:EHW89_RS02600
uniprot id: A0A3Q9EXS0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

2490633:EHW89 RS06500
gene id: 2490633:EHW89_RS06500
uniprot id: A0A3Q9EZ00
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

2490633:EHW89 RS02570
gene id: 2490633:EHW89_RS02570
uniprot id: A0A3Q9F3C5
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

2490633:EHW89 RS04845
gene id: 2490633:EHW89_RS04845
uniprot id: A0A3Q9EYJ8
names: Similarity
messages: Belongs to the BMP lipoprotein family.

2490633:EHW89 RS03670
gene id: 2490633:EHW89_RS03670
uniprot id: A0A3S9MQW5
names: Similarity
messages: Belongs to the YjdM family.

2490633:EHW89 RS01705
gene id: 2490633:EHW89_RS01705
uniprot id: A0A3Q9F2I7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

2490633:EHW89 RS04150
gene id: 2490633:EHW89_RS04150
uniprot id: A0A3S9MRC4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

2490633:EHW89 RS03305
gene id: 2490633:EHW89_RS03305
uniprot id: A0A3S9MQS3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

2490633:EHW89 RS07490
gene id: 2490633:EHW89_RS07490
uniprot id: A0A3S9MSZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MrnC RNase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc); Rnc processes 30S rRNA into smaller rRNA precursors.

2490633:EHW89 RS03410
gene id: 2490633:EHW89_RS03410
uniprot id: A0A3S9MQQ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CobB/CobQ family. GatD subfamily.
messages: Forms a heterodimer with MurT.
messages: The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The GatD subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia. The resulting ammonia molecule is channeled to the active site of MurT.

2490633:EHW89 RS07085
gene id: 2490633:EHW89_RS07085
uniprot id: A0A3Q9F3G9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family. YeeN subfamily.
messages: Cytoplasm

2490633:EHW89 RS08325
gene id: 2490633:EHW89_RS08325
uniprot id: A0A3Q9F508
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

2490633:EHW89 RS08295
gene id: 2490633:EHW89_RS08295
uniprot id: A0A3S9MTF2
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

2490633:EHW89 RS04830
gene id: 2490633:EHW89_RS04830
uniprot id: A0A3Q9F2P4
names: Subcellular Location Annotation
messages: Membrane

2490633:EHW89 RS05180
gene id: 2490633:EHW89_RS05180
uniprot id: A0A3S9MRT6
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

2490633:EHW89 RS04600
gene id: 2490633:EHW89_RS04600
uniprot id: A0A3Q9F2U8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2490633:EHW89 RS03880
gene id: 2490633:EHW89_RS03880
uniprot id: A0A3Q9F3T1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate.
messages: Cytoplasm

2490633:EHW89 RS08940
gene id: 2490633:EHW89_RS08940
uniprot id: A0A3Q9F4T7
names: Similarity
messages: Belongs to the bacterial solute-binding protein 1 family.

2490633:EHW89 RS05925
gene id: 2490633:EHW89_RS05925
uniprot id: A0A3S9MS66
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

2490633:EHW89 RS09210
gene id: 2490633:EHW89_RS09210
uniprot id: A0A3S9MTX0
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

2490633:EHW89 RS04040
gene id: 2490633:EHW89_RS04040
uniprot id: A0A3Q9F375
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

2490633:EHW89 RS03800
gene id: 2490633:EHW89_RS03800
uniprot id: A0A3Q9F357
names: Similarity
messages: Belongs to the NDK family.

2490633:EHW89 RS01375
gene id: 2490633:EHW89_RS01375
uniprot id: A0A3Q9F2Z2
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

2490633:EHW89 RS07215
gene id: 2490633:EHW89_RS07215
uniprot id: A0A3S9MSV4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Belongs to the P-Pant transferase superfamily. Gsp/Sfp/HetI/AcpT family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

2490633:EHW89 RS02595
gene id: 2490633:EHW89_RS02595
uniprot id: A0A3Q9F2Z3
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by GTP. Inhibited by UTP.
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2490633:EHW89 RS04650
gene id: 2490633:EHW89_RS04650
uniprot id: A0A3S9MRI2
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by fructose 1,6-bisphosphate (FBP).
messages: Belongs to the LDH/MDH superfamily. LDH family.
messages: Catalyzes the conversion of lactate to pyruvate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2490633:EHW89 RS08660
gene id: 2490633:EHW89_RS08660
uniprot id: A0A3Q9EZK0
names: Function
names: Similarity
messages: Belongs to the CpsD/CapB family.
messages: Involved in the regulation of capsular polysaccharide biosynthesis. Autophosphorylation of CpsD attenuates its activity and reduces the level of encapsulation. May be part of a complex that directs the coordinated polymerization and export to the cell surface of the capsular polysaccharide.

2490633:EHW89 RS06760
gene id: 2490633:EHW89_RS06760
uniprot id: A0A3S9MSP1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

2490633:EHW89 RS03820
gene id: 2490633:EHW89_RS03820
uniprot id: A0A3S9MR21
names: Function
names: Similarity
names: Subunit
messages: Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
messages: Homodimer and homohexamer; in equilibrium.
messages: Regulates transcriptional attenuation of the pyrimidine nucleotide (pyr) operon by binding in a uridine-dependent manner to specific sites on pyr mRNA. This disrupts an antiterminator hairpin in the RNA and favors formation of a downstream transcription terminator, leading to a reduced expression of downstream genes.

2490633:EHW89 RS04605
gene id: 2490633:EHW89_RS04605
uniprot id: A0A3S9MRI3
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

2490633:EHW89 RS01610
gene id: 2490633:EHW89_RS01610
uniprot id: A0A3S9MPV3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0291 family.
messages: Cytoplasm

2490633:EHW89 RS02655
gene id: 2490633:EHW89_RS02655
uniprot id: A0A3Q9F3H1
names: Subcellular Location Annotation
messages: Membrane

2490633:EHW89 RS08730
gene id: 2490633:EHW89_RS08730
uniprot id: A0A3Q9F557
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

2490633:EHW89 RS00065
gene id: 2490633:EHW89_RS00065
uniprot id: A0A3S9MP55
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm
messages: Purine salvage pathway enzyme that catalyzes the transfer of the ribosyl-5-phosphate group from 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to the N9 position of the 6-oxopurines hypoxanthine and guanine to form the corresponding ribonucleotides IMP (inosine 5'-monophosphate) and GMP (guanosine 5'-monophosphate), with the release of PPi.

2490633:EHW89 RS03540
gene id: 2490633:EHW89_RS03540
uniprot id: A0A3S9MQW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

2490633:EHW89 RS06165
gene id: 2490633:EHW89_RS06165
uniprot id: A0A3Q9F3Y1
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane.

2490633:EHW89 RS06325
gene id: 2490633:EHW89_RS06325
uniprot id: A0A3Q9F3A4
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Electron transport system for the ribonucleotide reductase system NrdEF.

2490633:EHW89 RS04435
gene id: 2490633:EHW89_RS04435
uniprot id: A0A3S9MRE5
names: Similarity
messages: Belongs to the site-specific recombinase resolvase family.

2490633:EHW89 RS01210
gene id: 2490633:EHW89_RS01210
uniprot id: A0A3Q9EXP2
names: Subcellular Location Annotation
messages: Cytoplasm

2490633:EHW89 RS05440
gene id: 2490633:EHW89_RS05440
uniprot id: A0A3Q9EYQ4
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

2490633:EHW89 RS01485
gene id: 2490633:EHW89_RS01485
uniprot id: A0A3S9MPW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

2490633:EHW89 RS06795
gene id: 2490633:EHW89_RS06795
uniprot id: A0A3Q9F4L5
names: Similarity
messages: Belongs to the acylphosphatase family.

2490633:EHW89 RS01835
gene id: 2490633:EHW89_RS01835
uniprot id: A0A3S9MQ46
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecU family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation.

2490633:EHW89 RS09185
gene id: 2490633:EHW89_RS09185
uniprot id: A0A3S9MTV4
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

2490633:EHW89 RS08545
gene id: 2490633:EHW89_RS08545
uniprot id: A0A3S9MTI4
names: Similarity
messages: Belongs to the EamA transporter family.

2490633:EHW89 RS04630
gene id: 2490633:EHW89_RS04630
uniprot id: A0A3Q9EYC5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

2490633:EHW89 RS08195
gene id: 2490633:EHW89_RS08195
uniprot id: A0A3Q9EZP5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

2490633:EHW89 RS02185
gene id: 2490633:EHW89_RS02185
uniprot id: A0A3S9MQ45
names: Similarity
messages: Belongs to the YggT family.

2490633:EHW89 RS09350
gene id: 2490633:EHW89_RS09350
uniprot id: A0A3S9MTY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1C family.
messages: Cell membrane
messages: Membrane

2490633:EHW89 RS04835
gene id: 2490633:EHW89_RS04835
uniprot id: A0A3S9MRM4
names: Subcellular Location Annotation
messages: Membrane

2490633:EHW89 RS02810
gene id: 2490633:EHW89_RS02810
uniprot id: A0A3Q9F326
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation.

2490633:EHW89 RS07560
gene id: 2490633:EHW89_RS07560
uniprot id: A0A3Q9F3F9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

2490633:EHW89 RS01390
gene id: 2490633:EHW89_RS01390
uniprot id: A0A3Q9F1Y0
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

2490633:EHW89 RS05875
gene id: 2490633:EHW89_RS05875
uniprot id: A0A3Q9F4A9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-I 3-dehydroquinase family.
messages: Homodimer.
messages: Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate.

2490633:EHW89 RS03695
gene id: 2490633:EHW89_RS03695
uniprot id: A0A3Q9EY32
names: Subcellular Location Annotation
messages: Membrane

2490633:EHW89 RS05860
gene id: 2490633:EHW89_RS05860
uniprot id: A0A3Q9EYT7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

2490633:EHW89 RS02325
gene id: 2490633:EHW89_RS02325
uniprot id: A0A3Q9F2U5
names: Subcellular Location Annotation
messages: Membrane

2490633:EHW89 RS00990
gene id: 2490633:EHW89_RS00990
uniprot id: A0A3S9MPM2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

2490633:EHW89 RS03830
gene id: 2490633:EHW89_RS03830
uniprot id: A0A3S9MR07
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

2490633:EHW89 RS08370
gene id: 2490633:EHW89_RS08370
uniprot id: A0A3S9MTF6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

2490633:EHW89 RS08300
gene id: 2490633:EHW89_RS08300
uniprot id: A0A3Q9F4I8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

2490633:EHW89 RS01425
gene id: 2490633:EHW89_RS01425
uniprot id: A0A3Q9EXH5
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

2490633:EHW89 RS00795
gene id: 2490633:EHW89_RS00795
uniprot id: A0A3Q9F2F8
names: Similarity
messages: Belongs to the YoeB family.

2490633:EHW89 RS03720
gene id: 2490633:EHW89_RS03720
uniprot id: A0A3Q9EY97
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

2490633:EHW89 RS01405
gene id: 2490633:EHW89_RS01405
uniprot id: A0A3Q9EXB2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

2490633:EHW89 RS07455
gene id: 2490633:EHW89_RS07455
uniprot id: A0A3Q9F4C2
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

2490633:EHW89 RS08060
gene id: 2490633:EHW89_RS08060
uniprot id: A0A3Q9F3M1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

2490633:EHW89 RS01890
gene id: 2490633:EHW89_RS01890
uniprot id: A0A3S9MQ25
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

2490633:EHW89 RS02970
gene id: 2490633:EHW89_RS02970
uniprot id: A0A3Q9EXY0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

2490633:EHW89 RS01435
gene id: 2490633:EHW89_RS01435
uniprot id: A0A3Q9EXR4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

2490633:EHW89 RS07950
gene id: 2490633:EHW89_RS07950
uniprot id: A0A3Q9EZB9
names: Similarity
messages: Belongs to the peptidase C69 family.

2490633:EHW89 RS07340
gene id: 2490633:EHW89_RS07340
uniprot id: A0A3S9MSX7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

2490633:EHW89 RS06395
gene id: 2490633:EHW89_RS06395
uniprot id: A0A3Q9EZ78
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

2490633:EHW89 RS02950
gene id: 2490633:EHW89_RS02950
uniprot id: A0A3Q9F3H4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
messages: Homotetramer.
messages: Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2490633:EHW89 RS03910
gene id: 2490633:EHW89_RS03910
uniprot id: A0A3S9MRB0
names: Similarity
messages: Belongs to the UPF0346 family.

2490633:EHW89 RS08160
gene id: 2490633:EHW89_RS08160
uniprot id: A0A3S9MTA2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

2490633:EHW89 RS04920
gene id: 2490633:EHW89_RS04920
uniprot id: A0A3S9MRP3
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

2490633:EHW89 RS04105
gene id: 2490633:EHW89_RS04105
uniprot id: A0A3S9MRA3
names: Subcellular Location Annotation
messages: Membrane

2490633:EHW89 RS04030
gene id: 2490633:EHW89_RS04030
uniprot id: A0A3S9MR87
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

2490633:EHW89 RS06965
gene id: 2490633:EHW89_RS06965
uniprot id: A0A3S9MSQ6
names: Similarity
messages: Belongs to the SAM hydrolase / SAM-dependent halogenase family.

2490633:EHW89 RS08275
gene id: 2490633:EHW89_RS08275
uniprot id: A0A3S9MTE2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

2490633:EHW89 RS08030
gene id: 2490633:EHW89_RS08030
uniprot id: A0A3Q9F5E9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acetylates the N-terminal alanine of ribosomal protein S18.
messages: Belongs to the acetyltransferase family. RimI subfamily.
messages: Cytoplasm

2490633:EHW89 RS02805
gene id: 2490633:EHW89_RS02805
uniprot id: A0A3Q9F2F6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division.

2490633:EHW89 RS06560
gene id: 2490633:EHW89_RS06560
uniprot id: A0A3Q9F4I2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

2490633:EHW89 RS08990
gene id: 2490633:EHW89_RS08990
uniprot id: A0A3S9MTS8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

2490633:EHW89 RS03470
gene id: 2490633:EHW89_RS03470
uniprot id: A0A3Q9F2K7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

2490633:EHW89 RS05040
gene id: 2490633:EHW89_RS05040
uniprot id: A0A3Q9F4U9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

2490633:EHW89 RS08400
gene id: 2490633:EHW89_RS08400
uniprot id: A0A3S9MTE5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

2490633:EHW89 RS05045
gene id: 2490633:EHW89_RS05045
uniprot id: A0A3S9MRQ8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein S19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein S19.

2490633:EHW89 RS04760
gene id: 2490633:EHW89_RS04760
uniprot id: A0A3Q9EYI8
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

2490633:EHW89 RS08140
gene id: 2490633:EHW89_RS08140
uniprot id: A0A3S9MTA3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

2490633:EHW89 RS08170
gene id: 2490633:EHW89_RS08170
uniprot id: A0A3S9MT99
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2490633:EHW89 RS02225
gene id: 2490633:EHW89_RS02225
uniprot id: A0A3S9MQH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0053 family.
messages: Membrane

2490633:EHW89 RS08355
gene id: 2490633:EHW89_RS08355
uniprot id: A0A3S9MTF7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

2490633:EHW89 RS08310
gene id: 2490633:EHW89_RS08310
uniprot id: A0A3S9MTC9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

2490633:EHW89 RS06245
gene id: 2490633:EHW89_RS06245
uniprot id: A0A3Q9EYX4
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
messages: Part of the 50S ribosomal subunit.

2490633:EHW89 RS01685
gene id: 2490633:EHW89_RS01685
uniprot id: A0A3S9MQ97
names: Similarity
messages: Belongs to the asp23 family.

2490633:EHW89 RS05275
gene id: 2490633:EHW89_RS05275
uniprot id: A0A3S9MRV1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArsC family. Spx subfamily.
messages: Cytoplasm
messages: Global transcriptional regulator that plays a key role in stress response and exerts either positive or negative regulation of genes. Acts by interacting with the C-terminal domain of the alpha subunit of the RNA polymerase (RNAP). This interaction can enhance binding of RNAP to the promoter region of target genes and stimulate their transcription, or block interaction of RNAP with activator.
messages: Interacts with the C-terminal domain of the alpha subunit of the RNAP.

2490633:EHW89 RS02995
gene id: 2490633:EHW89_RS02995
uniprot id: A0A3S9MQP6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

2490633:EHW89 RS03065
gene id: 2490633:EHW89_RS03065
uniprot id: A0A3S9MQQ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

2490633:EHW89 RS01680
gene id: 2490633:EHW89_RS01680
uniprot id: A0A3S9MQ15
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

2490633:EHW89 RS03465
gene id: 2490633:EHW89_RS03465
uniprot id: A0A3S9MQV0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-3 family.
messages: Cytoplasm
messages: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
messages: Monomer.

2490633:EHW89 RS04225
gene id: 2490633:EHW89_RS04225
uniprot id: A0A3Q9EY81
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

2490633:EHW89 RS06810
gene id: 2490633:EHW89_RS06810
uniprot id: A0A3S9MSQ3
names: Similarity
messages: Belongs to the Nudix hydrolase family.

2490633:EHW89 RS00635
gene id: 2490633:EHW89_RS00635
uniprot id: A0A3S9MPH2
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

2490633:EHW89 RS07275
gene id: 2490633:EHW89_RS07275
uniprot id: A0A3S9MSU6
names: Subcellular Location Annotation
messages: Membrane

2490633:EHW89 RS08320
gene id: 2490633:EHW89_RS08320
uniprot id: A0A3Q9EZQ1
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

2490633:EHW89 RS01455
gene id: 2490633:EHW89_RS01455
uniprot id: A0A3S9MPX8
names: Subcellular Location Annotation
messages: Membrane

2490633:EHW89 RS01600
gene id: 2490633:EHW89_RS01600
uniprot id: A0A3Q9F1T1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

2490633:EHW89 RS06430
gene id: 2490633:EHW89_RS06430
uniprot id: A0A3S9MSE6
names: Similarity
messages: Belongs to the LacAB/RpiB family.

2490633:EHW89 RS06730
gene id: 2490633:EHW89_RS06730
uniprot id: A0A3Q9F451
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

2490633:EHW89 RS07575
gene id: 2490633:EHW89_RS07575
uniprot id: A0A3S9MT31
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

2490633:EHW89 RS07050
gene id: 2490633:EHW89_RS07050
uniprot id: A0A3S9MSQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

2490633:EHW89 RS05525
gene id: 2490633:EHW89_RS05525
uniprot id: A0A3Q9F3R1
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.

2490633:EHW89 RS08735
gene id: 2490633:EHW89_RS08735
uniprot id: A0A3Q9F506
names: Similarity
messages: Belongs to the UPF0297 family.

2490633:EHW89 RS01760
gene id: 2490633:EHW89_RS01760
uniprot id: A0A3Q9F5B5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. Ycf16 family.
messages: Membrane

2490633:EHW89 RS02550
gene id: 2490633:EHW89_RS02550
uniprot id: A0A3Q9EY30
names: Subcellular Location Annotation
messages: Membrane

2490633:EHW89 RS00445
gene id: 2490633:EHW89_RS00445
uniprot id: A0A3S9MPB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

2490633:EHW89 RS09215
gene id: 2490633:EHW89_RS09215
uniprot id: A0A3S9MTW3
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

2490633:EHW89 RS08630
gene id: 2490633:EHW89_RS08630
uniprot id: A0A3Q9EZT3
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

2490633:EHW89 RS02195
gene id: 2490633:EHW89_RS02195
uniprot id: A0A3S9MQA1
names: Subcellular Location Annotation
messages: Cytoplasm

2490633:EHW89 RS03420
gene id: 2490633:EHW89_RS03420
uniprot id: A0A3S9MR15
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the adenylate cyclase family. DacA/CdaA subfamily.
messages: Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably a homodimer.

2490633:EHW89 RS06765
gene id: 2490633:EHW89_RS06765
uniprot id: A0A3Q9F402
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

2490633:EHW89 RS09040
gene id: 2490633:EHW89_RS09040
uniprot id: A0A3Q9F3X1
names: Similarity
messages: Belongs to the plasmid replication initiation factor family.

2490633:EHW89 RS05350
gene id: 2490633:EHW89_RS05350
uniprot id: A0A3Q9F2T7
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2490633:EHW89 RS05065
gene id: 2490633:EHW89_RS05065
uniprot id: A0A3Q9EYT3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

2490633:EHW89 RS00585
gene id: 2490633:EHW89_RS00585
uniprot id: A0A3S9MPG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

2490633:EHW89 RS03655
gene id: 2490633:EHW89_RS03655
uniprot id: A0A3S9MQX4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

2490633:EHW89 RS01950
gene id: 2490633:EHW89_RS01950
uniprot id: A0A3Q9F1W6
names: Similarity
messages: Belongs to the UPF0374 family.

2490633:EHW89 RS00070
gene id: 2490633:EHW89_RS00070
uniprot id: A0A3S9MPC8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

2490633:EHW89 RS03590
gene id: 2490633:EHW89_RS03590
uniprot id: A0A3Q9F381
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

2490633:EHW89 RS07975
gene id: 2490633:EHW89_RS07975
uniprot id: A0A3S9MT85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Cell membrane
messages: Membrane

2490633:EHW89 RS08335
gene id: 2490633:EHW89_RS08335
uniprot id: A0A3S9MTD6
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

2490633:EHW89 RS05840
gene id: 2490633:EHW89_RS05840
uniprot id: A0A3S9MS57
names: Similarity
messages: Belongs to the UPF0342 family.

2490633:EHW89 RS03835
gene id: 2490633:EHW89_RS03835
uniprot id: A0A3S9MR40
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

2490633:EHW89 RS08305
gene id: 2490633:EHW89_RS08305
uniprot id: A0A3Q9EZE8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

2490633:EHW89 RS05345
gene id: 2490633:EHW89_RS05345
uniprot id: A0A3Q9F3J0
names: Similarity
messages: Belongs to the pyruvate kinase family.

2490633:EHW89 RS09355
gene id: 2490633:EHW89_RS09355
uniprot id: A0A3Q9F490
names: Similarity
messages: Belongs to the ParB family.

2490633:EHW89 RS06415
gene id: 2490633:EHW89_RS06415
uniprot id: A0A3Q9F3B4
names: Subcellular Location Annotation
messages: Membrane

2490633:EHW89 RS08050
gene id: 2490633:EHW89_RS08050
uniprot id: A0A3Q9F4D6
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

2490633:EHW89 RS05250
gene id: 2490633:EHW89_RS05250
uniprot id: A0A3S9MRV8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

2490633:EHW89 RS04210
gene id: 2490633:EHW89_RS04210
uniprot id: A0A3S9MR76
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

2490633:EHW89 RS04330
gene id: 2490633:EHW89_RS04330
uniprot id: A0A3Q9F2J7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.

2490633:EHW89 RS01825
gene id: 2490633:EHW89_RS01825
uniprot id: A0A3Q9F2P1
names: Similarity
messages: Belongs to the peptidase C1 family.

2490633:EHW89 RS06770
gene id: 2490633:EHW89_RS06770
uniprot id: A0A3Q9F377
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0154 family.
messages: Cell membrane
messages: Membrane

2490633:EHW89 RS02365
gene id: 2490633:EHW89_RS02365
uniprot id: A0A3S9MQA9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the YabA family.
messages: Interacts with both DnaA and DnaN, acting as a bridge between these two proteins.
messages: Involved in initiation control of chromosome replication.

2490633:EHW89 RS07305
gene id: 2490633:EHW89_RS07305
uniprot id: A0A3S9MSV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

2490633:EHW89 RS01430
gene id: 2490633:EHW89_RS01430
uniprot id: A0A3S9MPS0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2490633:EHW89 RS08080
gene id: 2490633:EHW89_RS08080
uniprot id: A0A3S9MTA7
names: Similarity
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.

2490633:EHW89 RS03780
gene id: 2490633:EHW89_RS03780
uniprot id: A0A3Q9F2M9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acyl-ACP thioesterase family.
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: chloroplast

2490633:EHW89 RS07165
gene id: 2490633:EHW89_RS07165
uniprot id: A0A3S9MSS8
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

2490633:EHW89 RS02575
gene id: 2490633:EHW89_RS02575
uniprot id: A0A3S9MQE5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

2490633:EHW89 RS04140
gene id: 2490633:EHW89_RS04140
uniprot id: A0A3Q9F2I1
names: Similarity
messages: Belongs to the diacylglycerol/lipid kinase family.

2490633:EHW89 RS03500
gene id: 2490633:EHW89_RS03500
uniprot id: A0A3Q9EY12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uridine kinase family.
messages: Cytoplasm

2490633:EHW89 RS08340
gene id: 2490633:EHW89_RS08340
uniprot id: A0A3Q9F3X4
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

2490633:EHW89 RS01415
gene id: 2490633:EHW89_RS01415
uniprot id: A0A3Q9F1R1
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

2490633:EHW89 RS00485
gene id: 2490633:EHW89_RS00485
uniprot id: A0A3Q9EX81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase proteolipid subunit family.
messages: Membrane

2490633:EHW89 RS03825
gene id: 2490633:EHW89_RS03825
uniprot id: A0A3S9MR66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

2490633:EHW89 RS02955
gene id: 2490633:EHW89_RS02955
uniprot id: A0A3Q9F3K8
names: Similarity
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.

2490633:EHW89 RS01560
gene id: 2490633:EHW89_RS01560
uniprot id: A0A3Q9F350
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

2490633:EHW89 RS07310
gene id: 2490633:EHW89_RS07310
uniprot id: A0A3Q9EZG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

2490633:EHW89 RS08995
gene id: 2490633:EHW89_RS08995
uniprot id: A0A3Q9F573
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

2490633:EHW89 RS03965
gene id: 2490633:EHW89_RS03965
uniprot id: A0A3Q9EYH1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

2490633:EHW89 RS00210
gene id: 2490633:EHW89_RS00210
uniprot id: A0A3S9MP58
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

2490633:EHW89 RS00005
gene id: 2490633:EHW89_RS00005
uniprot id: A0A3Q9F1M2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

2490633:EHW89 RS06390
gene id: 2490633:EHW89_RS06390
uniprot id: A0A3S9MSH8
names: Cofactor
messages: Binds 1 Mg(2+) ion per trimer.

2490633:EHW89 RS01880
gene id: 2490633:EHW89_RS01880
uniprot id: A0A3S9MQ03
names: Function
names: Similarity
messages: Belongs to the RNase Y family.
messages: Endoribonuclease that initiates mRNA decay.

2490633:EHW89 RS06880
gene id: 2490633:EHW89_RS06880
uniprot id: A0A3Q9F4M4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

2490633:EHW89 RS02615
gene id: 2490633:EHW89_RS02615
uniprot id: A0A3Q9F249
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

2490633:EHW89 RS00920
gene id: 2490633:EHW89_RS00920
uniprot id: A0A3S9MPF6
names: Similarity
messages: Belongs to the ThrE exporter (TC 2.A.79) family.

2490633:EHW89 RS05505
gene id: 2490633:EHW89_RS05505
uniprot id: A0A3Q9F3L3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

2490633:EHW89 RS07645
gene id: 2490633:EHW89_RS07645
uniprot id: A0A3S9MT40
names: Similarity
messages: Belongs to the asp23 family.

2490633:EHW89 RS01220
gene id: 2490633:EHW89_RS01220
uniprot id: A0A3S9MPL4
names: Subcellular Location Annotation
messages: Membrane

2490633:EHW89 RS03105
gene id: 2490633:EHW89_RS03105
uniprot id: A0A3S9MQR7
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

2490633:EHW89 RS02135
gene id: 2490633:EHW89_RS02135
uniprot id: A0A3S9MQ33
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

2490633:EHW89 RS03570
gene id: 2490633:EHW89_RS03570
uniprot id: A0A3S9MQX2
names: Function
names: Similarity
messages: Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PDRP subfamily.
messages: Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation.

2490633:EHW89 RS02355
gene id: 2490633:EHW89_RS02355
uniprot id: A0A3Q9F296
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

2490633:EHW89 RS04775
gene id: 2490633:EHW89_RS04775
uniprot id: A0A3S9MRK9
names: Similarity
messages: Belongs to the PHP hydrolase family. HisK subfamily.

2490633:EHW89 RS04975
gene id: 2490633:EHW89_RS04975
uniprot id: A0A3Q9F407
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

2490633:EHW89 RS08490
gene id: 2490633:EHW89_RS08490
uniprot id: A0A3S9MTI9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

2490633:EHW89 RS01105
gene id: 2490633:EHW89_RS01105
uniprot id: A0A3S9MPP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

2490633:EHW89 RS01230
gene id: 2490633:EHW89_RS01230
uniprot id: A0A3S9MPL5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

2490633:EHW89 RS03340
gene id: 2490633:EHW89_RS03340
uniprot id: A0A3Q9F3N8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

2490633:EHW89 RS01660
gene id: 2490633:EHW89_RS01660
uniprot id: A0A3Q9F213
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

2490633:EHW89 RS01120
gene id: 2490633:EHW89_RS01120
uniprot id: A0A3S9MTZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

2490633:EHW89 RS05225
gene id: 2490633:EHW89_RS05225
uniprot id: A0A3Q9EYI4
names: Similarity
messages: Belongs to the UPF0758 family.

2490633:EHW89 RS03475
gene id: 2490633:EHW89_RS03475
uniprot id: A0A3S9MR37
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

2490633:EHW89 RS02650
gene id: 2490633:EHW89_RS02650
uniprot id: A0A3Q9F3E4
names: Similarity
messages: Belongs to the carbamate kinase family.

2490633:EHW89 RS05245
gene id: 2490633:EHW89_RS05245
uniprot id: A0A3S9MRU6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

2490633:EHW89 RS03115
gene id: 2490633:EHW89_RS03115
uniprot id: A0A3S9MQR4
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

2490633:EHW89 RS02075
gene id: 2490633:EHW89_RS02075
uniprot id: A0A3Q9EXQ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

2490633:EHW89 RS09095
gene id: 2490633:EHW89_RS09095
uniprot id: A0A3S9MTT9
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-DCP.
messages: Belongs to the DltC family.
messages: Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall.
messages: Cytoplasm

2490633:EHW89 RS05105
gene id: 2490633:EHW89_RS05105
uniprot id: A0A3S9MRS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

2490633:EHW89 RS06780
gene id: 2490633:EHW89_RS06780
uniprot id: A0A3Q9EZ06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

2490633:EHW89 RS04565
gene id: 2490633:EHW89_RS04565
uniprot id: A0A3S9MRH5
names: Similarity
messages: Belongs to the DprA/Smf family.

2490633:EHW89 RS03885
gene id: 2490633:EHW89_RS03885
uniprot id: A0A3S9MR53
names: Function
names: Similarity
names: Subunit
messages: Belongs to the OMP decarboxylase family. Type 1 subfamily.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
messages: Homodimer.

2490633:EHW89 RS07460
gene id: 2490633:EHW89_RS07460
uniprot id: A0A3S9MT06
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

2490633:EHW89 RS04730
gene id: 2490633:EHW89_RS04730
uniprot id: A0A3Q9F3I7
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

2490633:EHW89 RS04485
gene id: 2490633:EHW89_RS04485
uniprot id: A0A3Q9F3Y7
names: Function
names: Similarity
messages: Belongs to the UPF0122 family.
messages: Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein.

2490633:EHW89 RS02330
gene id: 2490633:EHW89_RS02330
uniprot id: A0A3Q9EXT3
names: Subcellular Location Annotation
messages: Membrane

2490633:EHW89 RS08315
gene id: 2490633:EHW89_RS08315
uniprot id: A0A3S9MTD5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

2490633:EHW89 RS01320
gene id: 2490633:EHW89_RS01320
uniprot id: A0A3S9MPS1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

2490633:EHW89 RS01750
gene id: 2490633:EHW89_RS01750
uniprot id: A0A3S9MPW8
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MecA family.
messages: Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis.
messages: Homodimer.
messages: The N-terminal domain probably binds unfolded/aggregated proteins; the C-terminal domain interacts with ClpC.

2490633:EHW89 RS08260
gene id: 2490633:EHW89_RS08260
uniprot id: A0A3S9MU54
names: Similarity
messages: Belongs to the CtsR family.

2490633:EHW89 RS06520
gene id: 2490633:EHW89_RS06520
uniprot id: A0A3S9MSF8
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

2490633:EHW89 RS01955
gene id: 2490633:EHW89_RS01955
uniprot id: A0A3Q9F2Q4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

2490633:EHW89 RS01410
gene id: 2490633:EHW89_RS01410
uniprot id: A0A3Q9F2G1
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

2490633:EHW89 RS01460
gene id: 2490633:EHW89_RS01460
uniprot id: A0A3Q9F341
names: Subcellular Location Annotation
messages: Membrane

2490633:EHW89 RS02485
gene id: 2490633:EHW89_RS02485
uniprot id: A0A3Q9F2Y2
names: Subcellular Location Annotation
messages: Cytoplasm

2490633:EHW89 RS08365
gene id: 2490633:EHW89_RS08365
uniprot id: A0A3Q9F3P6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

2490633:EHW89 RS02120
gene id: 2490633:EHW89_RS02120
uniprot id: A0A3Q9EXK9
names: Similarity
messages: Belongs to the Dps family.

2490633:EHW89 RS07300
gene id: 2490633:EHW89_RS07300
uniprot id: A0A3Q9EZ55
names: Function
names: Similarity
messages: Belongs to the ABC transporter superfamily.
messages: Part of the binding-protein-dependent transport system for oligopeptides. Probably responsible for energy coupling to the transport system.

2490633:EHW89 RS03600
gene id: 2490633:EHW89_RS03600
uniprot id: A0A3S9MR24
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

2490633:EHW89 RS03895
gene id: 2490633:EHW89_RS03895
uniprot id: A0A3Q9F3A7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2490633:EHW89 RS08420
gene id: 2490633:EHW89_RS08420
uniprot id: A0A3S9MTG6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.