244447:LOC103384643
gene id: 244447:LOC103384643
uniprot id: A0A3P8UJL7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 7 family.
messages: Golgi apparatus membrane
messages: Membrane
messages: Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids.

244447:rpl29
gene id: 244447:rpl29
uniprot id: A0A3P8VNX1
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL29 family.

244447:LOC103380544
gene id: 244447:LOC103380544
uniprot id: A0A3P8WHJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UCMA family.
messages: May be involved in the negative control of osteogenic differentiation of osteochondrogenic precursor cells in peripheral zones of fetal cartilage and at the cartilage-bone interface.
messages: extracellular matrix

244447:LOC103376765
gene id: 244447:LOC103376765
uniprot id: A0A3P8V6B8
uniprot id: A0A3P8V908
uniprot id: A0A3P8VEG0
names: Similarity
messages: Belongs to the MAGUK family.

244447:LOC103396945
gene id: 244447:LOC103396945
uniprot id: A0A3P8VFN0
uniprot id: A0A3P8VL25
names: Similarity
messages: Belongs to the FAM214 family.

244447:chac2
gene id: 244447:chac2
uniprot id: A0A3P8VNF8
names: Function
names: Similarity
messages: Belongs to the gamma-glutamylcyclotransferase family. ChaC subfamily.
messages: Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides.

244447:LOC103394567
gene id: 244447:LOC103394567
uniprot id: A0A3P8VHQ0
names: Cofactor
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS27 family.
messages: Binds 1 zinc ion per subunit.

244447:LOC103382302
gene id: 244447:LOC103382302
uniprot id: A0A3P8UFC3
names: Similarity
messages: Belongs to the actin family.

244447:LOC103383481
gene id: 244447:LOC103383481
uniprot id: A0A3P8ULZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

244447:eftud2
gene id: 244447:eftud2
uniprot id: A0A3P8WNT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Nucleus

244447:dact3
gene id: 244447:dact3
uniprot id: A0A3P8USY4
names: Similarity
messages: Belongs to the dapper family.

244447:LOC103385164
gene id: 244447:LOC103385164
uniprot id: A0A3P8VEG6
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

244447:LOC103378402
gene id: 244447:LOC103378402
uniprot id: A0A3P8UN55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ubiquitin family. SUMO subfamily.
messages: Nucleus

244447:slc35c1
gene id: 244447:slc35c1
uniprot id: A0A3P8URT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TPT transporter family. SLC35C subfamily.
messages: Membrane

244447:b4galnt1
gene id: 244447:b4galnt1
uniprot id: A0A3P8UXA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family.
messages: Golgi apparatus membrane
messages: Membrane

244447:LOC103395267
gene id: 244447:LOC103395267
uniprot id: A0A3P8W408
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

244447:LOC103395983
gene id: 244447:LOC103395983
uniprot id: A0A3P8WAU6
names: Similarity
messages: Belongs to the FAM102 family.

244447:LOC103392949
gene id: 244447:LOC103392949
uniprot id: A0A3P8W8D8
names: Subcellular Location Annotation
messages: Membrane

244447:LOC103393997
gene id: 244447:LOC103393997
uniprot id: A0A3P8VU75
names: Similarity
messages: Belongs to the annexin family.

244447:med29
gene id: 244447:med29
uniprot id: A0A3P8WLF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mediator complex subunit 29 family.
messages: Nucleus

244447:mblac1
gene id: 244447:mblac1
uniprot id: A0A3P8WC02
names: Similarity
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.

244447:LOC103397023
gene id: 244447:LOC103397023
uniprot id: A0A3P8WU65
names: Cofactor
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS27 family.
messages: Binds 1 zinc ion per subunit.

244447:LOC103381859
gene id: 244447:LOC103381859
uniprot id: A0A3P8WCW2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ORM family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Negative regulator of sphingolipid synthesis.

244447:rrp15
gene id: 244447:rrp15
uniprot id: A0A3P8VQN6
names: Similarity
messages: Belongs to the RRP15 family.

244447:LOC103383296
gene id: 244447:LOC103383296
uniprot id: A0A3P8WZF8
names: Similarity
messages: Belongs to the HEBP family.

244447:LOC103388909
gene id: 244447:LOC103388909
uniprot id: A0A3P8V409
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

244447:stk32a
gene id: 244447:stk32a
uniprot id: A0A3P8VYW3
names: Similarity
messages: Belongs to the protein kinase superfamily.

244447:zranb2
gene id: 244447:zranb2
uniprot id: A0A3P8VLM7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZRANB2 family.
messages: May interfere with constitutive 5'-splice site selection.
messages: Nucleus

244447:LOC103388378
gene id: 244447:LOC103388378
uniprot id: A0A3P8V3P0
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

244447:rps9
gene id: 244447:rps9
uniprot id: A0A3P8WSP5
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: Identified in a IGF2BP1-dependent mRNP granule complex containing untranslated mRNAs.

244447:fat2
gene id: 244447:fat2
uniprot id: A0A3P8W4X6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

244447:LOC103396227
gene id: 244447:LOC103396227
uniprot id: A0A3P8WXX0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

244447:LOC103392529
gene id: 244447:LOC103392529
uniprot id: A0A3P8WZ74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Membrane

244447:hhipl1
gene id: 244447:hhipl1
uniprot id: A0A3P8UW36
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

244447:slc10a4
gene id: 244447:slc10a4
uniprot id: A0A3P8WXY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bile acid:sodium symporter (BASS) (TC 2.A.28) family.
messages: Membrane

244447:med25
gene id: 244447:med25
uniprot id: A0A3P8VY44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mediator complex subunit 25 family.
messages: Nucleus

244447:LOC103394996
gene id: 244447:LOC103394996
uniprot id: A0A3P8WP56
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family.

244447:LOC103393099
gene id: 244447:LOC103393099
uniprot id: A0A3P8WEL2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

244447:cda
gene id: 244447:cda
uniprot id: A0A3P8V4D7
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

244447:LOC103390704
gene id: 244447:LOC103390704
uniprot id: A0A3P8V1S0
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

244447:tsr3
gene id: 244447:tsr3
uniprot id: A0A3P8W316
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Aminocarboxypropyltransferase that catalyzes the aminocarboxypropyl transfer on pseudouridine at position 1248 (Psi1248) in 18S rRNA. It constitutes the last step in biosynthesis of the hypermodified N1-methyl-N3-(3-amino-3-carboxypropyl) pseudouridine (m1acp3-Psi) conserved in eukaryotic 18S rRNA.
messages: Belongs to the TDD superfamily. TSR3 family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

244447:LOC103392743
gene id: 244447:LOC103392743
uniprot id: A0A3P8VJP4
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL19 family.
messages: Component of the large ribosomal subunit.

244447:LOC103384848
gene id: 244447:LOC103384848
uniprot id: A0A3P8UZ67
names: Subcellular Location Annotation
messages: Membrane

244447:LOC103385716
gene id: 244447:LOC103385716
uniprot id: A0A3P8UJG5
names: Caution
names: Subcellular Location Annotation
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

244447:LOC103384708
gene id: 244447:LOC103384708
uniprot id: A0A3P8UTX4
uniprot id: A0A3P8UWY7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.

244447:esco2
gene id: 244447:esco2
uniprot id: A0A3P8UT15
names: Subcellular Location Annotation
messages: Nucleus

244447:LOC103391314
gene id: 244447:LOC103391314
uniprot id: A0A3P8WM69
names: Function
names: Similarity
names: Subunit
messages: Belongs to the archaeal Rpo11/eukaryotic RPB11/RPC19 RNA polymerase subunit family.
messages: Component of the RNA polymerase I (Pol I) and RNA polymerase III (Pol III) complexes consisting of at least 13 and 17 subunits, respectively.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common core component of RNA polymerases I and III which synthesize ribosomal RNA precursors and small RNAs, such as 5S rRNA and tRNAs, respectively.

244447:btd
gene id: 244447:btd
uniprot id: A0A3P8VIR4
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. BTD/VNN family.

244447:LOC103397087
gene id: 244447:LOC103397087
uniprot id: A0A3P8VRV0
uniprot id: A0A3P8VUB9
names: Subcellular Location Annotation
messages: Endoplasmic reticulum
messages: Golgi apparatus

244447:LOC103390237
gene id: 244447:LOC103390237
uniprot id: A0A3P8WW98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: centrosome

244447:LOC103396283
gene id: 244447:LOC103396283
uniprot id: A0A3P8VTS4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Binds 2 magnesium ions per subunit. Is also active with manganese (in vitro).
messages: Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.
messages: Membrane

244447:borcs5
gene id: 244447:borcs5
uniprot id: A0A3P8UN71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BORCS5 family.
messages: Lysosome membrane
messages: Membrane

244447:LOC103397520
gene id: 244447:LOC103397520
uniprot id: A0A3P8W7F8
names: Similarity
messages: Belongs to the peptidase S8 family.

244447:slc2a2
gene id: 244447:slc2a2
uniprot id: A0A3P8UWD7
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

244447:rps3
gene id: 244447:rps3
uniprot id: A0A3P8W538
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Membrane
messages: Mitochondrion inner membrane
messages: nucleolus
messages: spindle

244447:LOC103385877
gene id: 244447:LOC103385877
uniprot id: A0A3P8US25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

244447:LOC103398044
gene id: 244447:LOC103398044
uniprot id: A0A3P8VNW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Orai family.
messages: Membrane

244447:LOC103389278
gene id: 244447:LOC103389278
uniprot id: A0A3P8UIM6
names: Similarity
messages: Belongs to the RGS7BP/RGS9BP family.

244447:smad7
gene id: 244447:smad7
uniprot id: A0A3P8WW49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dwarfin/SMAD family.
messages: Cytoplasm
messages: Nucleus

244447:slc10a7
gene id: 244447:slc10a7
uniprot id: A0A3P8V4H7
uniprot id: A0A3P8V4I2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bile acid:sodium symporter (BASS) (TC 2.A.28) family.
messages: Cell membrane
messages: Does not show transport activity towards bile acids or steroid sulfates.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane

244447:fam189a1
gene id: 244447:fam189a1
uniprot id: A0A3P8USJ5
names: Similarity
messages: Belongs to the ENTREP family.

244447:irak1bp1
gene id: 244447:irak1bp1
uniprot id: A0A3P8UKZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IRAK1BP1 family.
messages: Cytoplasm
messages: Nucleus

244447:sucnr1
gene id: 244447:sucnr1
uniprot id: A0A3P8VE58
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

244447:LOC103389863
gene id: 244447:LOC103389863
uniprot id: A0A3P8VJT3
names: Subcellular Location Annotation
messages: Nucleus

244447:LOC103380812
gene id: 244447:LOC103380812
uniprot id: A0A3P8X2A4
uniprot id: A0A3P8X426
names: Subcellular Location Annotation
messages: Membrane

244447:ntsr1
gene id: 244447:ntsr1
uniprot id: A0A3P8UR44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

244447:sod1
gene id: 244447:sod1
uniprot id: A0A3P8WUT0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Cu-Zn superoxide dismutase family.
messages: Binds 1 copper ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

244447:LOC103389730
gene id: 244447:LOC103389730
uniprot id: A0A3P8W8C8
uniprot id: A0A3P8W8E3
names: Subcellular Location Annotation
messages: Nucleus

244447:bcap31
gene id: 244447:bcap31
uniprot id: A0A3P8WND1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BCAP29/BCAP31 family.
messages: Endoplasmic reticulum membrane
messages: May play a role in anterograde transport of membrane proteins from the endoplasmic reticulum to the Golgi.
messages: Membrane

244447:pknox2
gene id: 244447:pknox2
uniprot id: A0A3P8WNH0
uniprot id: A0A3P8WNJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/MEIS homeobox family.
messages: Nucleus

244447:spata18
gene id: 244447:spata18
uniprot id: A0A3P8WVR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIEAP family.
messages: Cytoplasm
messages: Membrane
messages: Mitochondrion outer membrane

244447:ggt1
gene id: 244447:ggt1
uniprot id: A0A3P8UGG1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaves the gamma-glutamyl peptide bond of glutathione and glutathione conjugates.
messages: Membrane

244447:pex12
gene id: 244447:pex12
uniprot id: A0A3P8W3G0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pex2/pex10/pex12 family.
messages: Peroxisome membrane
messages: Required for protein import into peroxisomes.

244447:slc30a9
gene id: 244447:slc30a9
uniprot id: A0A3P8UXA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
messages: Cytoplasmic vesicle
messages: Endoplasmic reticulum
messages: Membrane
messages: Nucleus
messages: Vesicle

244447:elovl5
gene id: 244447:elovl5
uniprot id: A0A3P8VQH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELO family.
messages: Membrane

244447:LOC103394508
gene id: 244447:LOC103394508
uniprot id: A0A3P8VCM1
names: Similarity
messages: Belongs to the syntaxin family.

244447:ndufaf3
gene id: 244447:ndufaf3
uniprot id: A0A3P8ULZ5
names: Function
names: Subcellular Location Annotation
messages: Essential factor for the assembly of mitochondrial NADH:ubiquinone oxidoreductase complex (complex I).
messages: Membrane
messages: Mitochondrion inner membrane
messages: Nucleus

244447:kynu
gene id: 244447:kynu
uniprot id: A0A3P8UQ78
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the kynureninase family.
messages: Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

244447:tarbp2
gene id: 244447:tarbp2
uniprot id: A0A3P8VQA9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TARBP2 family.
messages: Cytoplasm
messages: Required for formation of the RNA induced silencing complex (RISC). Component of the RISC loading complex (RLC), also known as the micro-RNA (miRNA) loading complex (miRLC), which is composed of DICER1, AGO2 and TARBP2. Within the RLC/miRLC, DICER1 and TARBP2 are required to process precursor miRNAs (pre-miRNAs) to mature miRNAs and then load them onto AGO2. AGO2 bound to the mature miRNA constitutes the minimal RISC and may subsequently dissociate from DICER1 and TARBP2. May also play a role in the production of short interfering RNAs (siRNAs) from double-stranded RNA (dsRNA) by DICER1.
messages: Self-associates. Component of the RISC loading complex (RLC), or micro-RNA (miRNA) loading complex (miRLC), which is composed of DICER1, AGO2 and TARBP2. Note that the trimeric RLC/miRLC is also referred to as RISC.

244447:LOC103395687
gene id: 244447:LOC103395687
uniprot id: A0A3P8VES3
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

244447:crls1
gene id: 244447:crls1
uniprot id: A0A3P8WK62
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

244447:LOC103377168
gene id: 244447:LOC103377168
uniprot id: A0A3P8WCT0
uniprot id: A0A3P8WF11
names: Function
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and thereby links the glycolytic pathway to the tricarboxylic cycle.

244447:htr6
gene id: 244447:htr6
uniprot id: A0A3P8UUQ2
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

244447:eif4a2
gene id: 244447:eif4a2
uniprot id: A0A3P8WGY3
names: Similarity
messages: Belongs to the DEAD box helicase family. eIF4A subfamily.

244447:snta1
gene id: 244447:snta1
uniprot id: A0A3P8WTU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the syntrophin family.
messages: Cell junction
messages: cytoskeleton

244447:kif3c
gene id: 244447:kif3c
uniprot id: A0A3P8UY97
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

244447:LOC103379195
gene id: 244447:LOC103379195
uniprot id: A0A3P8VGU6
names: Similarity
messages: Belongs to the taxilin family.

244447:vma21
gene id: 244447:vma21
uniprot id: A0A3P8W6M7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VMA21 family.
messages: COPII-coated vesicle membrane
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Required for the assembly of the V0 complex of the vacuolar ATPase (V-ATPase) in the endoplasmic reticulum.

244447:tfpi2
gene id: 244447:tfpi2
uniprot id: A0A3P8VXE0
names: Subcellular Location Annotation
messages: Secreted

244447:map1lc3a
gene id: 244447:map1lc3a
uniprot id: A0A3P8WX17
names: Similarity
messages: Belongs to the ATG8 family.

244447:LOC103393557
gene id: 244447:LOC103393557
uniprot id: A0A3P8W020
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

244447:emc7
gene id: 244447:emc7
uniprot id: A0A3P8UY90
names: Similarity
names: Subunit
messages: Belongs to the EMC7 family.
messages: Component of the ER membrane protein complex (EMC).

244447:emp2
gene id: 244447:emp2
uniprot id: A0A3P8WXC4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the PMP-22/EMP/MP20 family.
messages: Cell membrane
messages: Golgi apparatus membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Membrane raft
messages: Nucleus
messages: perinuclear region

244447:adgra3
gene id: 244447:adgra3
uniprot id: A0A3P8V947
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily.
messages: Membrane

244447:LOC103398284
gene id: 244447:LOC103398284
uniprot id: A0A3P8WHR6
names: Subcellular Location Annotation
messages: Membrane

244447:LOC103395822
gene id: 244447:LOC103395822
uniprot id: A0A3P8VUJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NASP family.
messages: Nucleus

244447:calhm3
gene id: 244447:calhm3
uniprot id: A0A3P8WMF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CALHM family.
messages: Membrane

244447:LOC103394115
gene id: 244447:LOC103394115
uniprot id: A0A3P8VW93
names: Similarity
messages: Belongs to the MARCKS family.

244447:npnt
gene id: 244447:npnt
uniprot id: A0A3P8ULU4
names: Caution
names: Similarity
messages: Belongs to the nephronectin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

244447:tm4sf4
gene id: 244447:tm4sf4
uniprot id: A0A3P8WY11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L6 tetraspanin family.
messages: Membrane

244447:LOC103395883
gene id: 244447:LOC103395883
uniprot id: F2YHV1
names: Similarity
names: Subunit
messages: Belongs to the GILT family.
messages: Dimer; disulfide-linked.

244447:LOC103396452
gene id: 244447:LOC103396452
uniprot id: A0A3P8W739
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calycin superfamily. Lipocalin family.
messages: Secreted

244447:ntrk3
gene id: 244447:ntrk3
uniprot id: A0A3P8VVX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. Insulin receptor subfamily.
messages: Cell membrane
messages: Membrane

244447:cpne2
gene id: 244447:cpne2
uniprot id: A0A3P8WCY0
names: Similarity
messages: Belongs to the copine family.

244447:spty2d1
gene id: 244447:spty2d1
uniprot id: A0A3P8VEL3
names: Similarity
messages: Belongs to the SPT2 family.

244447:dynlt1
gene id: 244447:dynlt1
uniprot id: A0A3P8WSM7
names: Similarity
messages: Belongs to the dynein light chain Tctex-type family.

244447:stk38l
gene id: 244447:stk38l
uniprot id: A0A3P8WKI2
names: Similarity
messages: Belongs to the protein kinase superfamily.

244447:LOC103378992
gene id: 244447:LOC103378992
uniprot id: A0A3P8VFE2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. Peptidase M19 family.
messages: Homodimer; disulfide-linked.
messages: Membrane

244447:mixl1
gene id: 244447:mixl1
uniprot id: A0A3P8X4W8
names: Subcellular Location Annotation
messages: Nucleus

244447:ergic3
gene id: 244447:ergic3
uniprot id: A0A3P8WX39
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERGIC family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Golgi apparatus membrane
messages: Plays a role in transport between endoplasmic reticulum and Golgi.

244447:wisp3
gene id: 244447:wisp3
uniprot id: A0A3P8WGQ6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCN family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

244447:LOC103378112
gene id: 244447:LOC103378112
uniprot id: A0A3P8VHJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the X(+)/potassium ATPases subunit beta family.
messages: Membrane
messages: This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane.

244447:LOC103397290
gene id: 244447:LOC103397290
uniprot id: A0A3P8WXG9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELO family. ELOVL1 subfamily.
messages: Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that exhibits activity toward saturated C18 to C26 acyl-CoA substrates, with the highest activity towards C22:0 acyl-CoA. May participate to the production of both saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: The C-terminal di-lysine motif may confer endoplasmic reticulum localization.

244447:taf6l
gene id: 244447:taf6l
uniprot id: A0A3P8WEC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF6 family.
messages: Nucleus

244447:LOC103390293
gene id: 244447:LOC103390293
uniprot id: A0A3P8WY69
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Cell membrane
messages: May play a role in neurite outgrowth and neurogenesis.
messages: Membrane
messages: neuron projection

244447:LOC103382736
gene id: 244447:LOC103382736
uniprot id: A0A3P8VCA7
names: Similarity
messages: Belongs to the ARTD/PARP family.

244447:LOC103398184
gene id: 244447:LOC103398184
uniprot id: A0A3P8W6R3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the unc-5 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for netrin required for axon guidance. Mediates axon repulsion of neuronal growth cones in the developing nervous system upon ligand binding.

244447:LOC103397964
gene id: 244447:LOC103397964
uniprot id: A0A3P8VL11
names: Subcellular Location Annotation
messages: Nucleus

244447:tfb1m
gene id: 244447:tfb1m
uniprot id: A0A3P8UE81
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.

244447:pgpep1
gene id: 244447:pgpep1
uniprot id: A0A3P8WFX9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C15 family.
messages: Cytoplasm
messages: Removes 5-oxoproline from various penultimate amino acid residues except L-proline.

244447:LOC103381510
gene id: 244447:LOC103381510
uniprot id: A0A3P8VDC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic mitochondrial porin family.
messages: Mitochondrion outer membrane

244447:LOC103395030
gene id: 244447:LOC103395030
uniprot id: A0A3P8WQ17
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

244447:LOC103380018
gene id: 244447:LOC103380018
uniprot id: A0A3P8UPL4
uniprot id: A0A3P8UY19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

244447:LOC103384408
gene id: 244447:LOC103384408
uniprot id: A0A3P8WLP4
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

244447:LOC103380168
gene id: 244447:LOC103380168
uniprot id: A0A3P8VAB4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Muscarinic acetylcholine receptor subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Postsynaptic cell membrane
messages: The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins.

244447:gdap2
gene id: 244447:gdap2
uniprot id: A0A3P8VK94
names: Similarity
messages: Belongs to the GDAP2 family.

244447:tmem45b
gene id: 244447:tmem45b
uniprot id: A0A3P8VIH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM45 family.
messages: Membrane

244447:LOC103392869
gene id: 244447:LOC103392869
uniprot id: A0A3P8VXI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Cell surface
messages: Endosome
messages: Membrane

244447:LOC103376684
gene id: 244447:LOC103376684
uniprot id: A0A3P8UUA6
names: Cofactor
names: Similarity
messages: Belongs to the transglutaminase superfamily. Transglutaminase family.
messages: Binds 1 Ca(2+) ion per subunit.

244447:LOC103377766
gene id: 244447:LOC103377766
uniprot id: A0A3P8ULT7
names: Subcellular Location Annotation
messages: Nucleus

244447:ggps1
gene id: 244447:ggps1
uniprot id: A0A3P8W735
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

244447:LOC103389012
gene id: 244447:LOC103389012
uniprot id: A0A3P8W7W0
names: Similarity
messages: Belongs to the apolipoprotein A1/A4/E family.

244447:ddx21
gene id: 244447:ddx21
uniprot id: A0A3P8W2P4
names: Similarity
messages: Belongs to the DEAD box helicase family. DDX21/DDX50 subfamily.

244447:LOC103394965
gene id: 244447:LOC103394965
uniprot id: A0A3P8WF39
names: Similarity
messages: Belongs to the protein kinase superfamily. CK1 Ser/Thr protein kinase family. Casein kinase I subfamily.

244447:LOC103395035
gene id: 244447:LOC103395035
uniprot id: A0A3P8WWB4
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. RAC subfamily.

244447:eaf2
gene id: 244447:eaf2
uniprot id: A0A3P8V0X9
names: Similarity
messages: Belongs to the EAF family.

244447:LOC103378929
gene id: 244447:LOC103378929
uniprot id: A0A3P8VAL2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Adaptor protein complex 2 (AP-2) is a heterotetramer composed of two large adaptins (alpha-type subunit AP2A1 or AP2A2 and beta-type subunit AP2B1), a medium adaptin (mu-type subunit AP2M1) and a small adaptin (sigma-type subunit AP2S1).
messages: Belongs to the adaptor complexes large subunit family.
messages: Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but is itself unable to bind directly to membrane components. Clathrin-associated adaptor protein (AP) complexes which can bind directly to both the clathrin lattice and to the lipid and protein components of membranes are considered to be the major clathrin adaptors contributing the CCV formation. AP-2 also serves as a cargo receptor to selectively sort the membrane proteins involved in receptor-mediated endocytosis. AP-2 seems to play a role in the recycling of synaptic vesicle membranes from the presynaptic surface. AP-2 recognizes Y-X-X-[FILMV] (Y-X-X-Phi) and [ED]-X-X-X-L-[LI] endocytosis signal motifs within the cytosolic tails of transmembrane cargo molecules. AP-2 may also play a role in maintaining normal post-endocytic trafficking through the ARF6-regulated, non-clathrin pathway. The AP-2 alpha subunit binds polyphosphoinositide-containing lipids, positioning AP-2 on the membrane. The AP-2 alpha subunit acts via its C-terminal appendage domain as a scaffolding platform for endocytic accessory proteins. The AP-2 alpha and AP-2 sigma subunits are thought to contribute to the recognition of the [ED]-X-X-X-L-[LI] motif.
messages: coated pit

244447:LOC103390844
gene id: 244447:LOC103390844
uniprot id: A0A3P8V8W8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 6-O-sulfation enzyme which catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to position 6 of the N-sulfoglucosamine residue (GlcNS) of heparan sulfate.
messages: Belongs to the sulfotransferase 6 family.
messages: Membrane

244447:LOC103388894
gene id: 244447:LOC103388894
uniprot id: A0A3P8V3J1
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily.

244447:meaf6
gene id: 244447:meaf6
uniprot id: A0A3P8VPL1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EAF6 family.
messages: Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histone H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. Component of HBO1 complexes, which specifically mediate acetylation of histone H3 at 'Lys-14' (H3K14ac), and have reduced activity toward histone H4. Component of the MOZ/MORF complex which has a histone H3 acetyltransferase activity.
messages: Component of the NuA4 histone acetyltransferase complex. Component of the hbo1 complex. Component of the moz/morf complex.
messages: kinetochore
messages: nucleolus

244447:mef2c
gene id: 244447:mef2c
uniprot id: A0A3P8W3W1
names: Subcellular Location Annotation
messages: Nucleus

244447:polr2a
gene id: 244447:polr2a
uniprot id: A0A3P8UTQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA polymerase beta' chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Nucleus

244447:rhbdf2
gene id: 244447:rhbdf2
uniprot id: A0A3P8VEH0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S54 family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Regulates ADAM17 protease, a sheddase of the epidermal growth factor (EGF) receptor ligands and TNF, thereby plays a role in sleep, cell survival, proliferation, migration and inflammation. Does not exhibit any protease activity on its own.

244447:LOC103395911
gene id: 244447:LOC103395911
uniprot id: A0A3P8W9D4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

244447:LOC103380538
gene id: 244447:LOC103380538
uniprot id: A0A3P8WF69
names: Subcellular Location Annotation
messages: cytoskeleton

244447:map3k7
gene id: 244447:map3k7
uniprot id: A0A3P8WPM3
uniprot id: A0A3P8WUV4
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.

244447:capn15
gene id: 244447:capn15
uniprot id: A0A3P8WXU3
names: Similarity
messages: Belongs to the peptidase C2 family.

244447:syt1
gene id: 244447:syt1
uniprot id: A0A3P8UV14
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptotagmin family.
messages: Binds 3 Ca(2+) ions per subunit. The ions are bound to the C2 domains.
messages: May have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse. It binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone.
messages: Membrane
messages: chromaffin granule membrane
messages: synaptic vesicle membrane

244447:LOC103386800
gene id: 244447:LOC103386800
uniprot id: A0A3P8UA88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DAN family.
messages: Secreted

244447:elp1
gene id: 244447:elp1
uniprot id: A0A3P8W0K3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELP1/IKA1 family.
messages: Component of the elongator complex which is required for multiple tRNA modifications, including mcm5U (5-methoxycarbonylmethyl uridine), mcm5s2U (5-methoxycarbonylmethyl-2-thiouridine), and ncm5U (5-carbamoylmethyl uridine). The elongator complex catalyzes formation of carboxymethyluridine in the wobble base at position 34 in tRNAs.
messages: Cytoplasm
messages: Nucleus

244447:kif1b
gene id: 244447:kif1b
uniprot id: A0A3P8V6T5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
messages: axon

244447:LOC103390779
gene id: 244447:LOC103390779
uniprot id: A0A3P8V5C6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OXA1/ALB3/YidC family.
messages: Membrane

244447:LOC103389921
gene id: 244447:LOC103389921
uniprot id: A0A3P8VP28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Membrane

244447:top3b
gene id: 244447:top3b
uniprot id: A0A3P8VKB6
names: Function
names: Similarity
messages: Belongs to the type IA topoisomerase family.
messages: Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand.

244447:prickle1
gene id: 244447:prickle1
uniprot id: A0A3P8VLS8
uniprot id: A0A3P8VV20
names: Similarity
messages: Belongs to the prickle / espinas / testin family.

244447:LOC103384593
gene id: 244447:LOC103384593
uniprot id: A0A3P8UJ19
names: Similarity
messages: Belongs to the p23/wos2 family.

244447:LOC107988495
gene id: 244447:LOC107988495
uniprot id: A0A3P8UTN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.
messages: Membrane

244447:mrpl4
gene id: 244447:mrpl4
uniprot id: A0A3P8X306
names: Similarity
messages: Belongs to the universal ribosomal protein uL4 family.

244447:vps33a
gene id: 244447:vps33a
uniprot id: A0A3P8WFT1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STXBP/unc-18/SEC1 family.
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane

244447:rbp2
gene id: 244447:rbp2
uniprot id: A0A3P8W249
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

244447:hnmt
gene id: 244447:hnmt
uniprot id: A0A3P8W9F4
names: Subunit
messages: Monomer.

244447:dram1
gene id: 244447:dram1
uniprot id: A0A3P8VDQ7
names: Subcellular Location Annotation
messages: Membrane

244447:LOC103376956
gene id: 244447:LOC103376956
uniprot id: A0A3P8VHL8
names: Subcellular Location Annotation
messages: Membrane

244447:LOC103388206
gene id: 244447:LOC103388206
uniprot id: A0A3P8UMB1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the krueppel C2H2-type zinc-finger protein family.
messages: May be involved in transcriptional regulation.
messages: Nucleus

244447:nr3c2
gene id: 244447:nr3c2
uniprot id: A0A3P8UBS6
names: Subcellular Location Annotation
messages: Nucleus

244447:tmc5
gene id: 244447:tmc5
uniprot id: A0A3P8VS96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMC family.
messages: Membrane

244447:ppm1l
gene id: 244447:ppm1l
uniprot id: A0A3P8WKT3
names: Similarity
messages: Belongs to the PP2C family.

244447:LOC103392844
gene id: 244447:LOC103392844
uniprot id: A0A3P8W091
names: Subcellular Location Annotation
messages: Membrane

244447:LOC103388165
gene id: 244447:LOC103388165
uniprot id: A0A3P8UI94
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pentraxin family.
messages: Binds 2 calcium ions per subunit.
messages: Homopentamer. Pentaxin (or pentraxin) have a discoid arrangement of 5 non-covalently bound subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

244447:edem1
gene id: 244447:edem1
uniprot id: A0A3P8X4Q8
names: Similarity
messages: Belongs to the glycosyl hydrolase 47 family.

244447:mrpl51
gene id: 244447:mrpl51
uniprot id: A0A3P8WUT5
names: Similarity
messages: Belongs to the mitochondrion-specific ribosomal protein mL51 family.

244447:slc39a3
gene id: 244447:slc39a3
uniprot id: A0A3P8VG14
names: Subcellular Location Annotation
messages: Membrane

244447:zdhhc22
gene id: 244447:zdhhc22
uniprot id: A0A3P8UIK6
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

244447:znf532
gene id: 244447:znf532
uniprot id: A0A3P8WTL1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the krueppel C2H2-type zinc-finger protein family.
messages: May be involved in transcriptional regulation.
messages: Nucleus

244447:arfgef1
gene id: 244447:arfgef1
uniprot id: A0A3P8W824
uniprot id: A0A3P8WAU8
names: Subcellular Location Annotation
messages: Golgi apparatus
messages: perinuclear region

244447:LOC103396635
gene id: 244447:LOC103396635
uniprot id: A0A3P8X244
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Membrane

244447:fam69a
gene id: 244447:fam69a
uniprot id: A0A3P8WT29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DIPK family.
messages: Endoplasmic reticulum membrane

244447:gstk1
gene id: 244447:gstk1
uniprot id: A0A3P8WXS5
names: Similarity
messages: Belongs to the GST superfamily. Kappa family.

244447:LOC103377236
gene id: 244447:LOC103377236
uniprot id: A0A3P8WI03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0389 family.
messages: Membrane

244447:LOC103393992
gene id: 244447:LOC103393992
uniprot id: A0A3P8VUA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 47 family.
messages: Endoplasmic reticulum membrane

244447:amacr
gene id: 244447:amacr
uniprot id: A0A3P8UD91
names: Similarity
messages: Belongs to the CoA-transferase III family.

244447:snapin
gene id: 244447:snapin
uniprot id: A0A3P8WHE1
names: Similarity
messages: Belongs to the SNAPIN family.

244447:LOC103382512
gene id: 244447:LOC103382512
uniprot id: A0A3P8UVE2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bestrophin family.
messages: Cell membrane
messages: Forms chloride channels.
messages: Membrane

244447:LOC103392967
gene id: 244447:LOC103392967
uniprot id: A0A3P8W152
names: Similarity
messages: Belongs to the BACURD family.

244447:catl
gene id: 244447:catl
uniprot id: A0A3P8WS77
uniprot id: G9D326
names: Similarity
messages: Belongs to the peptidase C1 family.

244447:LOC103395122
gene id: 244447:LOC103395122
uniprot id: A0A3P8VMJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dynein light chain family.
messages: cytoskeleton

244447:LOC103384192
gene id: 244447:LOC103384192
uniprot id: A0A3P8WBB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

244447:LOC103387066
gene id: 244447:LOC103387066
uniprot id: A0A3P8USC9
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. RAC subfamily.

244447:LOC103397698
gene id: 244447:LOC103397698
uniprot id: A0A3P8WP49
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM134/TMEM230 family.
messages: Early endosome
messages: Endosome
messages: Involved in trafficking and recycling of synaptic vesicles.
messages: Late endosome
messages: Membrane
messages: Recycling endosome
messages: Vesicle
messages: autophagosome
messages: synaptic vesicle
messages: trans-Golgi network

244447:has2
gene id: 244447:has2
uniprot id: A0A3P8W031
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NodC/HAS family.
messages: Endoplasmic reticulum membrane
messages: Lysosome
messages: Membrane

244447:ccne2
gene id: 244447:ccne2
uniprot id: A0A3P8X2R8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cyclin family. Cyclin AB subfamily.
messages: Belongs to the cyclin family. Cyclin E subfamily.
messages: Essential for the control of the cell cycle at the G2/M (mitosis) transition.
messages: Interacts with the CDK1 protein kinase to form a serine/threonine kinase holoenzyme complex also known as maturation promoting factor (MPF). The cyclin subunit imparts substrate specificity to the complex.

244447:LOC103391240
gene id: 244447:LOC103391240
uniprot id: A0A3P8WHC9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

244447:czh12orf65
gene id: 244447:czh12orf65
uniprot id: A0A3P8W8I6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Mitochondrion

244447:LOC103378130
gene id: 244447:LOC103378130
uniprot id: A0A3P8VL94
names: Similarity
messages: Belongs to the NipSnap family.

244447:immt
gene id: 244447:immt
uniprot id: A0A3P8X3V7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MICOS complex subunit Mic60 family.
messages: Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.
messages: Component of the mitochondrial contact site and cristae organizing system (MICOS) complex.
messages: Mitochondrion inner membrane

244447:oat
gene id: 244447:oat
uniprot id: A0A3P8WPY9
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

244447:LOC103384968
gene id: 244447:LOC103384968
uniprot id: A0A3P8V352
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endothelin/sarafotoxin family.
messages: Secreted

244447:LOC103388208
gene id: 244447:LOC103388208
uniprot id: A0A3P8UM87
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pentraxin family.
messages: Binds 2 calcium ions per subunit.
messages: Homopentamer. Pentaxin (or pentraxin) have a discoid arrangement of 5 non-covalently bound subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

244447:hmox1
gene id: 244447:hmox1
uniprot id: A0A3P8WDL7
names: Similarity
messages: Belongs to the heme oxygenase family.

244447:mdk
gene id: 244447:mdk
uniprot id: R9QMX1
names: Similarity
messages: Belongs to the pleiotrophin family.

244447:mmaa
gene id: 244447:mmaa
uniprot id: A0A3P8UIU9
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

244447:LOC103398034
gene id: 244447:LOC103398034
uniprot id: A0A060DAT4
names: Subcellular Location Annotation
names: Subunit
messages: May interact with TSPO.
messages: Mitochondrion

244447:cap1
gene id: 244447:cap1
uniprot id: A0A3P8VPX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAP family.
messages: Cell membrane

244447:trpm5
gene id: 244447:trpm5
uniprot id: A0A3P8UNF2
names: Subcellular Location Annotation
messages: Membrane

244447:LOC103385739
gene id: 244447:LOC103385739
uniprot id: A0A3P8UK44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.
messages: Cell membrane
messages: Membrane

244447:rcan1
gene id: 244447:rcan1
uniprot id: A0A3P8W037
uniprot id: A0A3P8W5M2
names: Similarity
messages: Belongs to the RCAN family.

244447:brf1
gene id: 244447:brf1
uniprot id: A0A3P8VYX9
names: Similarity
messages: Belongs to the TFIIB family.
messages: Belongs to the cyclin family. Cyclin AB subfamily.

244447:LOC103388448
gene id: 244447:LOC103388448
uniprot id: A0A3P8UXL5
names: Subcellular Location Annotation
messages: Early endosome
messages: Endosome

244447:LOC103385211
gene id: 244447:LOC103385211
uniprot id: A0A3P8VIX7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Heterooligomer of subunits alpha (IDH3A), beta (IDH3B), and gamma (IDH3G) in the apparent ratio of 2:1:1. The heterodimer containing one IDH3A and one IDH3B subunit and the heterodimer containing one IDH3A and one IDH3G subunit assemble into a heterotetramer (which contains two subunits of IDH3A, one of IDH3B and one of IDH3G) and further into the heterooctamer.
messages: Mitochondrion

244447:ralb
gene id: 244447:ralb
uniprot id: A0A3P8W8M1
names: Similarity
messages: Belongs to the small GTPase superfamily. Ras family.

244447:sdha
gene id: 244447:sdha
uniprot id: A0A3P8VWY3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).
messages: Mitochondrion inner membrane

244447:LOC103397702
gene id: 244447:LOC103397702
uniprot id: A0A3P8WIQ1
names: Similarity
messages: Belongs to the phosphatase 2A regulatory subunit B family.

244447:rax
gene id: 244447:rax
uniprot id: A0A3P8X1D5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paired homeobox family. Bicoid subfamily.
messages: Nucleus
messages: Plays a critical role in eye formation by regulating the initial specification of retinal cells and/or their subsequent proliferation.

244447:LOC103379459
gene id: 244447:LOC103379459
uniprot id: A0A3P8W4I0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

244447:arglu1
gene id: 244447:arglu1
uniprot id: A0A3P8WF90
uniprot id: A0A3P8WI13
names: Similarity
messages: Belongs to the UPF0430 family.

244447:mfsd3
gene id: 244447:mfsd3
uniprot id: A0A3P8W4Y2
names: Subcellular Location Annotation
messages: Membrane

244447:kif1bp
gene id: 244447:kif1bp
uniprot id: A0A3P8WBI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KIF-binding protein family.
messages: cytoskeleton

244447:LOC103398054
gene id: 244447:LOC103398054
uniprot id: A0A3P8VNX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Vesicular transporter family.
messages: Membrane

244447:abat
gene id: 244447:abat
uniprot id: A0A3P8VV85
names: Similarity
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer; disulfide-linked.

244447:LOC103380981
gene id: 244447:LOC103380981
uniprot id: A0A3P8UFR2
names: Similarity
messages: Belongs to the CD225/Dispanin family.

244447:LOC103385226
gene id: 244447:LOC103385226
uniprot id: A0A3P8W9I3
names: Similarity
messages: Belongs to the protein kinase superfamily.

244447:LOC103387382
gene id: 244447:LOC103387382
uniprot id: A0A3P8VJC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prominin family.
messages: Membrane
messages: microvillus membrane

244447:LOC103379102
gene id: 244447:LOC103379102
uniprot id: A0A3P8VXY4
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Putative Notch ligand involved in the mediation of Notch signaling.

244447:LOC103377555
gene id: 244447:LOC103377555
uniprot id: A0A3P8UJB1
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

244447:tex261
gene id: 244447:tex261
uniprot id: A0A3P8UWN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SVP26 family.
messages: Membrane

244447:mcub
gene id: 244447:mcub
uniprot id: A0A3P8VS82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCU (TC 1.A.77) family.
messages: Membrane
messages: Mitochondrion inner membrane

244447:ebna1bp2
gene id: 244447:ebna1bp2
uniprot id: A0A3P8WVC5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EBP2 family.
messages: Required for the processing of the 27S pre-rRNA.
messages: nucleolus

244447:kat5
gene id: 244447:kat5
uniprot id: A0A3P8W5M6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MYST (SAS/MOZ) family.
messages: Nucleus

244447:LOC103387405
gene id: 244447:LOC103387405
uniprot id: A0A3P8VLZ0
names: Function
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
messages: Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues within the same substrate, with a preference for phosphotyrosine as a substrate (By similarity). Involved in the modulation of AMPK and MAPK1/2 signaling pathways.
messages: Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate.

244447:vezt
gene id: 244447:vezt
uniprot id: A0A3P8V022
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vezatin family.
messages: Cell membrane
messages: Membrane
messages: Nucleus
messages: adherens junction

244447:rnft2
gene id: 244447:rnft2
uniprot id: A0A3P8X5Y2
names: Subcellular Location Annotation
messages: Membrane

244447:rbl1
gene id: 244447:rbl1
uniprot id: A0A3P8WXX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cyclin family. Cyclin AB subfamily.
messages: Belongs to the retinoblastoma protein (RB) family.
messages: Nucleus

244447:LOC103379409
gene id: 244447:LOC103379409
uniprot id: G9FTP5
names: Similarity
messages: Belongs to the peptidase C1 family.

244447:LOC103378509
gene id: 244447:LOC103378509
uniprot id: A0A3P8WP83
names: Subcellular Location Annotation
messages: Membrane

244447:rexo4
gene id: 244447:rexo4
uniprot id: A0A3P8WXT5
names: Similarity
messages: Belongs to the REXO4 family.

244447:LOC103390928
gene id: 244447:LOC103390928
uniprot id: A0A3P8VPZ3
names: Subcellular Location Annotation
messages: Cytoplasm

244447:eipr1
gene id: 244447:eipr1
uniprot id: A0A3P8UC95
names: Similarity
messages: Belongs to the WD repeat EIPR1 family.

244447:trmt6
gene id: 244447:trmt6
uniprot id: A0A3P8UNH5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRM6/GCD10 family.
messages: Heterotetramer.
messages: Nucleus
messages: Substrate-binding subunit of tRNA (adenine-N1-)-methyltransferase, which catalyzes the formation of N1-methyladenine at position 58 (m1A58) in initiator methionyl-tRNA.

244447:cnnm3
gene id: 244447:cnnm3
uniprot id: A0A3P8VV53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ACDP family.
messages: Membrane

244447:khdrbs3
gene id: 244447:khdrbs3
uniprot id: A0A3P8W2X5
names: Similarity
messages: Belongs to the KHDRBS family.

244447:anxa4
gene id: 244447:anxa4
uniprot id: A0A3P8UIY2
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: A pair of annexin repeats may form one binding site for calcium and phospholipid.
messages: Belongs to the annexin family.
messages: Zymogen granule membrane

244447:LOC103389533
gene id: 244447:LOC103389533
uniprot id: A0A3P8V766
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: phagosome membrane

244447:tmem132e
gene id: 244447:tmem132e
uniprot id: A0A3P8VQL6
uniprot id: A0A3P8VTK1
uniprot id: A0A3P8VW38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM132 family.
messages: Membrane

244447:sh3gl1
gene id: 244447:sh3gl1
uniprot id: A0A3P8URL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endophilin family.
messages: Membrane

244447:mapkap1
gene id: 244447:mapkap1
uniprot id: A0A3P8VA95
names: Similarity
messages: Belongs to the SIN1 family.

244447:LOC103383986
gene id: 244447:LOC103383986
uniprot id: A0A3P8VM33
names: Subcellular Location Annotation
messages: Nucleus

244447:ppp1r14c
gene id: 244447:ppp1r14c
uniprot id: A0A3P8UQS0
names: Similarity
messages: Belongs to the PP1 inhibitor family.

244447:actr8
gene id: 244447:actr8
uniprot id: A0A3P8V8G1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the actin family. ARP8 subfamily.
messages: Chromosome
messages: Component of the chromatin remodeling INO80 complex; specifically part of a complex module associated with the DBINO domain of INO80. Exists as monomers and dimers, but the dimer is most probably the biologically relevant form required for stable interactions with histones that exploits the twofold symmetry of the nucleosome core.
messages: Nucleus
messages: Plays an important role in the functional organization of mitotic chromosomes. Exhibits low basal ATPase activity, and unable to polymerize.
messages: Proposed core component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair.

244447:bloc1s1
gene id: 244447:bloc1s1
uniprot id: A0A3P8WQD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BLOC1S1 family.
messages: Mitochondrion intermembrane space

244447:LOC103377296
gene id: 244447:LOC103377296
uniprot id: A0A3P8WUG7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

244447:LOC103394628
gene id: 244447:LOC103394628
uniprot id: A0A3P8VNB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 10 family.
messages: Golgi stack membrane

244447:trim45
gene id: 244447:trim45
uniprot id: A0A3P8UX71
names: Similarity
messages: Belongs to the TRIM/RBCC family.

244447:cpsf6
gene id: 244447:cpsf6
uniprot id: A0A3P8VF82
uniprot id: A0A3P8VHZ1
uniprot id: A0A3P8VND6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM CPSF6/7 family.
messages: Cytoplasm
messages: Nucleus speckle
messages: nucleoplasm

244447:smpx
gene id: 244447:smpx
uniprot id: A0A3P8UG43
names: Function
names: Similarity
messages: Belongs to the SMPX family.
messages: Plays a role in the regulatory network through which muscle cells coordinate their structural and functional states during growth, adaptation, and repair.

244447:rpl37
gene id: 244447:rpl37
uniprot id: A0A3P8UNR2
names: Function
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL37 family.
messages: Component of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.

244447:LOC103395095
gene id: 244447:LOC103395095
uniprot id: A0A3P8VGN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Cationic amino acid transporter (CAT) (TC 2.A.3.3) family.
messages: Cell membrane
messages: Membrane

244447:cuedc2
gene id: 244447:cuedc2
uniprot id: A0A3P8V2U2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CUEDC2 family.
messages: Cytoplasm
messages: Nucleus

244447:LOC103385576
gene id: 244447:LOC103385576
uniprot id: A0A3P8X372
names: Similarity
messages: Belongs to the SAPAP family.

244447:nudt18
gene id: 244447:nudt18
uniprot id: A0A3P8VRN4
names: Similarity
messages: Belongs to the Nudix hydrolase family.

244447:LOC103386279
gene id: 244447:LOC103386279
uniprot id: A0A3P8VBJ2
names: Caution
names: Subcellular Location Annotation
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

244447:opa3
gene id: 244447:opa3
uniprot id: A0A3P8V2R2
names: Function
names: Similarity
messages: Belongs to the OPA3 family.
messages: May play some role in mitochondrial processes.

244447:LOC103380037
gene id: 244447:LOC103380037
uniprot id: A0A3P8UU07
names: Similarity
messages: Belongs to the V-ATPase E subunit family.

244447:lrit1
gene id: 244447:lrit1
uniprot id: A0A3P8WP16
names: Subcellular Location Annotation
messages: Membrane

244447:dlx2
gene id: 244447:dlx2
uniprot id: A0A3P8VIB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the distal-less homeobox family.
messages: Nucleus

244447:LOC107989939
gene id: 244447:LOC107989939
uniprot id: A0A3P8VME1
names: Similarity
messages: Belongs to the apolipoprotein A1/A4/E family.

244447:gmppb
gene id: 244447:gmppb
uniprot id: A0A3P8WR55
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

244447:ubl4a
gene id: 244447:ubl4a
uniprot id: A0A3P8W958
names: Subcellular Location Annotation
messages: cytosol

244447:hoxa3
gene id: 244447:hoxa3
uniprot id: A0A3P8WA22
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

244447:LOC103395130
gene id: 244447:LOC103395130
uniprot id: A0A3P8VIV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family.
messages: Membrane

244447:psmd6
gene id: 244447:psmd6
uniprot id: A0A3P8V049
names: Similarity
messages: Belongs to the proteasome subunit S10 family.

244447:irf5
gene id: 244447:irf5
uniprot id: A0A3P8VA35
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IRF family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

244447:crat
gene id: 244447:crat
uniprot id: A0A3P8WP90
names: Similarity
messages: Belongs to the carnitine/choline acetyltransferase family.

244447:napg
gene id: 244447:napg
uniprot id: A0A3P8WGC6
names: Similarity
messages: Belongs to the SNAP family.

244447:ackr4
gene id: 244447:ackr4
uniprot id: A0A3P8UMU5
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

244447:LOC103384969
gene id: 244447:LOC103384969
uniprot id: A0A3P8UZA0
names: Subcellular Location Annotation
messages: Membrane

244447:hsd17b12
gene id: 244447:hsd17b12
uniprot id: A0A3P8ULP0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

244447:ppp3r1
gene id: 244447:ppp3r1
uniprot id: A0A3P8UJH9
names: Similarity
messages: Belongs to the calcineurin regulatory subunit family.

244447:LOC103388445
gene id: 244447:LOC103388445
uniprot id: A0A3P8V192
uniprot id: A0A3P8V438
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CLPTM1 family.
messages: Membrane

244447:dopey2
gene id: 244447:dopey2
uniprot id: A0A3P8VNX4
names: Similarity
messages: Belongs to the dopey family.

244447:LOC103379082
gene id: 244447:LOC103379082
uniprot id: A0A3P8VZI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dwarfin/SMAD family.
messages: Cytoplasm
messages: Nucleus

244447:LOC103378694
gene id: 244447:LOC103378694
uniprot id: A0A3P8UEW8
names: Similarity
messages: Belongs to the TMEM178 family.

244447:LOC103393628
gene id: 244447:LOC103393628
uniprot id: A0A3P8W8Y6
uniprot id: A0A3P8WEA1
names: Subcellular Location Annotation
messages: Nucleus

244447:LOC103383490
gene id: 244447:LOC103383490
uniprot id: A0A3P8UK42
names: Subcellular Location Annotation
messages: Membrane
messages: Mitochondrion outer membrane

244447:ttll1
gene id: 244447:ttll1
uniprot id: A0A3P8VD34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tubulin polyglutamylase family.
messages: cilium basal body

244447:pcyox1
gene id: 244447:pcyox1
uniprot id: A0A3P8UK02
names: Similarity
messages: Belongs to the prenylcysteine oxidase family.

244447:LOC103384774
gene id: 244447:LOC103384774
uniprot id: A0A3P8UW09
names: Similarity
messages: Belongs to the TCF/LEF family.

244447:cav3
gene id: 244447:cav3
uniprot id: A0A3P8UN91
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the caveolin family.
messages: Cell membrane
messages: Golgi apparatus membrane
messages: May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity.
messages: Membrane
messages: caveola

244447:LOC103381456
gene id: 244447:LOC103381456
uniprot id: A0A3P8V7H3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

244447:LOC103390702
gene id: 244447:LOC103390702
uniprot id: A0A3P8UUZ3
names: Subcellular Location Annotation
messages: Nucleus

244447:znf711
gene id: 244447:znf711
uniprot id: A0A3P8WE96
names: Subcellular Location Annotation
messages: Nucleus

244447:alx1
gene id: 244447:alx1
uniprot id: A0A3P8X2R7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paired homeobox family.
messages: Nucleus

244447:pim1
gene id: 244447:pim1
uniprot id: A0A3P8UMZ9
names: Function
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PIM subfamily.
messages: Proto-oncogene with serine/threonine kinase activity involved in cell survival and cell proliferation.

244447:map2k2
gene id: 244447:map2k2
uniprot id: A0A3P8V0N5
names: Similarity
messages: Belongs to the protein kinase superfamily.

244447:kat2a
gene id: 244447:kat2a
uniprot id: A0A3P8WM70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetyltransferase family. GCN5 subfamily.
messages: Nucleus
messages: centrosome

244447:nemf
gene id: 244447:nemf
uniprot id: A0A3P8UY61
names: Similarity
messages: Belongs to the NEMF family.

244447:slc10a3
gene id: 244447:slc10a3
uniprot id: A0A3P8X4D1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bile acid:sodium symporter (BASS) (TC 2.A.28) family.
messages: Membrane

244447:mfn1
gene id: 244447:mfn1
uniprot id: A0A3P8W6E2
names: Subcellular Location Annotation
messages: Membrane
messages: Mitochondrion outer membrane

244447:zbtb8os
gene id: 244447:zbtb8os
uniprot id: A0A3P8UIW3
names: Similarity
names: Subunit
messages: Belongs to the archease family.
messages: Component of the tRNA-splicing ligase complex.

244447:LOC103394735
gene id: 244447:LOC103394735
uniprot id: A0A3P8VS36
uniprot id: A0A3P8VXK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

244447:pus7l
gene id: 244447:pus7l
uniprot id: A0A3P8VUX2
names: Similarity
messages: Belongs to the pseudouridine synthase TruD family.

244447:LOC103379596
gene id: 244447:LOC103379596
uniprot id: A0A3P8X394
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 1 family. Gal/GlcNAc/GalNAc subfamily.
messages: Membrane

244447:nif3l1
gene id: 244447:nif3l1
uniprot id: A0A3P8WT25
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

244447:tmem128
gene id: 244447:tmem128
uniprot id: A0A3P8VG74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the otopetrin family.
messages: Cell membrane
messages: Membrane

244447:psmd3
gene id: 244447:psmd3
uniprot id: A0A3P8VDZ6
names: Similarity
messages: Belongs to the proteasome subunit S3 family.

244447:LOC103396884
gene id: 244447:LOC103396884
uniprot id: A0A3P8VHD8
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

244447:LOC103394566
gene id: 244447:LOC103394566
uniprot id: A0A3P8V8W7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

244447:LOC103395998
gene id: 244447:LOC103395998
uniprot id: A0A3P8WDT8
uniprot id: A0A3P8WGA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the shaker potassium channel beta subunit family.
messages: Cell membrane
messages: Cytoplasm
messages: Membrane

244447:lrig3
gene id: 244447:lrig3
uniprot id: A0A3P8WA66
names: Subcellular Location Annotation
messages: Membrane

244447:cd200r1
gene id: 244447:cd200r1
uniprot id: A0A3P8VTU6
uniprot id: A0A3P8VTX9
names: Similarity
messages: Belongs to the CD200R family.

244447:LOC103377787
gene id: 244447:LOC103377787
uniprot id: A0A3P8V655
names: Subcellular Location Annotation
messages: Membrane

244447:LOC103382540
gene id: 244447:LOC103382540
uniprot id: A0A3P8UW89
names: Similarity
messages: Belongs to the NLRP family.

244447:rsl24d1
gene id: 244447:rsl24d1
uniprot id: A0A3P8VXP0
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL24 family.

244447:usp10
gene id: 244447:usp10
uniprot id: A0A3P8UPK2
uniprot id: A0A3P8UPK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C19 family. USP10 subfamily.
messages: Cytoplasm
messages: Nucleus

244447:phka1
gene id: 244447:phka1
uniprot id: A0A3P8UBW2
uniprot id: A0A3P8UFV0
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Although the final Cys may be farnesylated, the terminal tripeptide is probably not removed, and the C-terminus is not methylated.
messages: Belongs to the phosphorylase b kinase regulatory chain family.
messages: Cell membrane
messages: Membrane
messages: Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. The alpha chain may bind calmodulin.

244447:LOC103393558
gene id: 244447:LOC103393558
uniprot id: A0A3P8WCB9
names: Similarity
messages: Belongs to the guanylate kinase family.

244447:mvb12a
gene id: 244447:mvb12a
uniprot id: A0A3P8W2Y6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MVB12 family.
messages: Endosome membrane
messages: Late endosome membrane
messages: Membrane

244447:slitrk5
gene id: 244447:slitrk5
uniprot id: A0A3P8VSN1
names: Similarity
messages: Belongs to the SLITRK family.

244447:b4gat1
gene id: 244447:b4gat1
uniprot id: A0A3P8UJV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 49 family.
messages: Golgi apparatus membrane
messages: Membrane

244447:LOC103395117
gene id: 244447:LOC103395117
uniprot id: A0A3P8VMN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IAP family.
messages: Cytoplasm
messages: Nucleus

244447:fam83f
gene id: 244447:fam83f
uniprot id: A0A3P8UN77
names: Similarity
messages: Belongs to the FAM83 family.

244447:per3
gene id: 244447:per3
uniprot id: A0A3P8V3M1
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

244447:LOC103376823
gene id: 244447:LOC103376823
uniprot id: A0A3P8VNE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 3 family.
messages: Membrane

244447:LOC103379831
gene id: 244447:LOC103379831
uniprot id: A0A3P8UM00
names: Similarity
messages: Belongs to the ric-3 family.

244447:LOC103390983
gene id: 244447:LOC103390983
uniprot id: A0A3P8VPK1
names: Similarity
messages: Belongs to the class I fructose-bisphosphate aldolase family.

244447:KEH01 p02
gene id: 244447:KEH01_p02
uniprot id: C5H0G4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I.
messages: Mitochondrion membrane

244447:fam98b
gene id: 244447:fam98b
uniprot id: A0A3P8V066
names: Similarity
messages: Belongs to the FAM98 family.

244447:kpna6
gene id: 244447:kpna6
uniprot id: A0A3P8VPK4
names: Similarity
messages: Belongs to the importin alpha family.

244447:cdh15
gene id: 244447:cdh15
uniprot id: A0A3P8UH36
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane
messages: Membrane

244447:LOC103386769
gene id: 244447:LOC103386769
uniprot id: A0A3P8WXW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TDE1 family.
messages: Membrane

244447:LOC103393163
gene id: 244447:LOC103393163
uniprot id: A0A3P8WNG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.
messages: Membrane

244447:cant1
gene id: 244447:cant1
uniprot id: A0A3P8VNM6
names: Similarity
messages: Belongs to the apyrase family.

244447:LOC103394411
gene id: 244447:LOC103394411
uniprot id: A0A3P8WMR1
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.

244447:gja1
gene id: 244447:gja1
uniprot id: A0A3P8WBU1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family. Alpha-type (group II) subfamily.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

244447:cdkl1
gene id: 244447:cdkl1
uniprot id: A0A3P8VD70
names: Similarity
messages: Belongs to the protein kinase superfamily.

244447:czh12orf49
gene id: 244447:czh12orf49
uniprot id: A0A3P8X502
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPRING family.
messages: Golgi apparatus membrane
messages: Membrane

244447:itprip
gene id: 244447:itprip
uniprot id: A0A3P8WBN9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ITPRIP family.
messages: Cell membrane
messages: Enhances Ca(2+)-mediated inhibition of inositol 1,4,5-triphosphate receptor (ITPR) Ca(2+) release.
messages: Membrane
messages: Nucleus outer membrane

244447:fam53b
gene id: 244447:fam53b
uniprot id: A0A3P8WJG4
names: Similarity
messages: Belongs to the FAM53 family.

244447:nudcd1
gene id: 244447:nudcd1
uniprot id: A0A3P8VF78
uniprot id: A0A3P8VI74
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

244447:LOC103389031
gene id: 244447:LOC103389031
uniprot id: A0A3P8WCM9
names: Function
messages: Plays a role in skin pigmentation by antagonizing the action of melanotropin alpha. Induces melanin concentration within the melanophores. May participate in the control of the hypothalamo-pituitary adrenal gland axis by inhibiting the release of ACTH.

244447:tmem231
gene id: 244447:tmem231
uniprot id: A0A3P8X4I6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM231 family.
messages: Membrane
messages: Transmembrane component of the tectonic-like complex, a complex localized at the transition zone of primary cilia and acting as a barrier that prevents diffusion of transmembrane proteins between the cilia and plasma membranes. Required for ciliogenesis and sonic hedgehog/SHH signaling.
messages: cilium membrane

244447:homer2
gene id: 244447:homer2
uniprot id: A0A3P8VJ19
uniprot id: A0A3P8VLX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Homer family.
messages: Postsynaptic density
messages: Synapse

244447:ocrl
gene id: 244447:ocrl
uniprot id: A0A3P8UPM6
uniprot id: A0A3P8UVL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inositol 1,4,5-trisphosphate 5-phosphatase type II family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Membrane
messages: phagosome membrane

244447:LOC103380197
gene id: 244447:LOC103380197
uniprot id: A0A3P8UZ28
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 6-O-sulfation enzyme which catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to position 6 of the N-sulfoglucosamine residue (GlcNS) of heparan sulfate.
messages: Belongs to the sulfotransferase 6 family.
messages: Membrane

244447:rab33a
gene id: 244447:rab33a
uniprot id: A0A3P8WDI9
names: Similarity
messages: Belongs to the small GTPase superfamily. Rab family.

244447:LOC103390639
gene id: 244447:LOC103390639
uniprot id: A0A3P8UXG3
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.

244447:LOC103378570
gene id: 244447:LOC103378570
uniprot id: A0A3P8WT77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM120 family.
messages: Membrane
messages: Nucleus inner membrane

244447:LOC103381737
gene id: 244447:LOC103381737
uniprot id: A0A3P8VYY1
names: Subcellular Location Annotation
messages: Membrane

244447:foxq1
gene id: 244447:foxq1
uniprot id: A0A3P8VQ13
names: Subcellular Location Annotation
messages: Nucleus

244447:LOC103389280
gene id: 244447:LOC103389280
uniprot id: A0A3P8UJZ8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complement C6/C7/C8/C9 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

244447:xkrx
gene id: 244447:xkrx
uniprot id: A0A3P8UPU8
uniprot id: A0A3P8UT46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XK family.
messages: Membrane

244447:epcam
gene id: 244447:epcam
uniprot id: A0A3P8UCR2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPCAM family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

244447:LOC103397589
gene id: 244447:LOC103397589
uniprot id: A0A3P8WK53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. JAK subfamily.
messages: Endomembrane system
messages: Nucleus

244447:dennd6b
gene id: 244447:dennd6b
uniprot id: A0A3P8VA71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DENND6 family.
messages: Endosome
messages: Recycling endosome

244447:gng5
gene id: 244447:gng5
uniprot id: A0A3P8VIV5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G protein gamma family.
messages: Cell membrane
messages: G proteins are composed of 3 units; alpha, beta and gamma.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

244447:LOC103393551
gene id: 244447:LOC103393551
uniprot id: A0A3P8W2H7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adaptor complexes small subunit family.
messages: COPI-coated vesicle membrane
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.
messages: The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properties with the coatomer complex.

244447:LOC103397895
gene id: 244447:LOC103397895
uniprot id: A0A3P8UIB7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TIKI family.
messages: Cell membrane
messages: Divalent metal cations. Mn(2+) or Co(2+).
messages: Membrane
messages: Metalloprotease that acts as a negative regulator of the Wnt signaling pathway by mediating the cleavage of the N-terminal residues of a subset of Wnt proteins. Following cleavage, Wnt proteins become oxidized and form large disulfide-bond oligomers, leading to their inactivation.

244447:slc7a14
gene id: 244447:slc7a14
uniprot id: A0A3P8WEI4
names: Subcellular Location Annotation
messages: Membrane

244447:LOC103398200
gene id: 244447:LOC103398200
uniprot id: A0A3P8W327
names: Similarity
messages: Belongs to the AAA ATPase family.

244447:mapkapk2
gene id: 244447:mapkapk2
uniprot id: A0A3P8UUW0
names: Similarity
messages: Belongs to the protein kinase superfamily.

244447:LOC103380669
gene id: 244447:LOC103380669
uniprot id: A0A3P8WLZ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nuclear hormone receptor family. NR3 subfamily.
messages: Binds DNA as a homodimer. Can form a heterodimer with ER-beta.
messages: Nucleus
messages: The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.

244447:LOC103392937
gene id: 244447:LOC103392937
uniprot id: A0A3P8W3H7
names: Subcellular Location Annotation
messages: Nucleus

244447:mlec
gene id: 244447:mlec
uniprot id: A0A3P8WLE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the malectin family.
messages: Endoplasmic reticulum membrane
messages: Membrane

244447:LOC103382149
gene id: 244447:LOC103382149
uniprot id: A0A3P8WZE9
uniprot id: A0A3P8X4D7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. PAR subfamily.
messages: Nucleus

244447:rpl23
gene id: 244447:rpl23
uniprot id: A0A3P8W5D6
names: Similarity
messages: Belongs to the universal ribosomal protein uL14 family.

244447:LOC103379778
gene id: 244447:LOC103379778
uniprot id: A0A3P8X4S7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.
messages: Membrane

244447:gfra1
gene id: 244447:gfra1
uniprot id: A0A3P8V4M3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: 2 molecules of GDNFR-alpha are thought to form a complex with the disulfide-linked GDNF dimer and with 2 molecules of RET.
messages: Belongs to the GDNFR family.
messages: Cell membrane
messages: Membrane
messages: Receptor for GDNF. Mediates the GDNF-induced autophosphorylation and activation of the RET receptor.

244447:LOC103386518
gene id: 244447:LOC103386518
uniprot id: A0A3P8WDD7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A6 subfamily.
messages: Cell membrane
messages: Membrane

244447:nt5c3b
gene id: 244447:nt5c3b
uniprot id: A0A3P8WJF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrimidine 5'-nucleotidase family.
messages: Cytoplasm

244447:LOC103388527
gene id: 244447:LOC103388527
uniprot id: A0A3P8V624
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

244447:efna1
gene id: 244447:efna1
uniprot id: A0A3P8UN61
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ephrin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

244447:LOC103393553
gene id: 244447:LOC103393553
uniprot id: A0A3P8W5K4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. CNC subfamily.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Nucleus

244447:ctnnb1
gene id: 244447:ctnnb1
uniprot id: A0A1W6BQH7
names: Similarity
messages: Belongs to the beta-catenin family.

244447:nop56
gene id: 244447:nop56
uniprot id: A0A3P8VD58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOP5/NOP56 family.
messages: nucleolus

244447:tada2a
gene id: 244447:tada2a
uniprot id: A0A3P8W0M8
names: Subcellular Location Annotation
messages: Nucleus

244447:LOC103385944
gene id: 244447:LOC103385944
uniprot id: A0A3P8UX54
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: GTP-binding protein involved in protein trafficking; modulates vesicle budding and uncoating within the Golgi apparatus.
messages: Golgi apparatus

244447:LOC103382708
gene id: 244447:LOC103382708
uniprot id: A0A3P8V9Q8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cyclin family. Cyclin AB subfamily.
messages: Belongs to the cyclin family. Cyclin D subfamily.
messages: Cytoplasm
messages: Essential for the control of the cell cycle at the G2/M (mitosis) transition.
messages: Interacts with the CDK1 protein kinase to form a serine/threonine kinase holoenzyme complex also known as maturation promoting factor (MPF). The cyclin subunit imparts substrate specificity to the complex.
messages: Nucleus

244447:coq10b
gene id: 244447:coq10b
uniprot id: A0A3P8UW19
names: Function
names: Similarity
names: Subunit
messages: Belongs to the COQ10 family.
messages: Interacts with coenzyme Q.
messages: Required for the function of coenzyme Q in the respiratory chain. May serve as a chaperone or may be involved in the transport of Q6 from its site of synthesis to the catalytic sites of the respiratory complexes.

244447:LOC103385939
gene id: 244447:LOC103385939
uniprot id: A0A3P8UX35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.
messages: Cell membrane
messages: Membrane

244447:LOC103395899
gene id: 244447:LOC103395899
uniprot id: A0A3P8W224
uniprot id: A0A3P8W523
names: Similarity
messages: Belongs to the dynein intermediate chain family.

244447:LOC103381992
gene id: 244447:LOC103381992
uniprot id: A0A3P8WTI3
names: Subcellular Location Annotation
messages: Membrane

244447:LOC103396969
gene id: 244447:LOC103396969
uniprot id: A0A075EYB0
names: Similarity
messages: Belongs to the GADD45 family.

244447:tube1
gene id: 244447:tube1
uniprot id: A0A3P8UQN1
names: Similarity
messages: Belongs to the tubulin family.

244447:etnppl
gene id: 244447:etnppl
uniprot id: A0A3P8VA52
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

244447:LOC103380988
gene id: 244447:LOC103380988
uniprot id: A0A3P8UBV7
names: Similarity
messages: Belongs to the heat shock protein 90 family.

244447:LOC103396327
gene id: 244447:LOC103396327
uniprot id: A0A3P8WTW3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neurexin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

244447:LOC103380555
gene id: 244447:LOC103380555
uniprot id: A0A3P8WAZ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GOT1 family.
messages: Golgi apparatus membrane
messages: May be involved in fusion of ER-derived transport vesicles with the Golgi complex.
messages: Membrane

244447:gnrh2
gene id: 244447:gnrh2
uniprot id: A0A1B1XZ36
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GnRH family.
messages: Secreted
messages: Stimulates the secretion of gonadotropins.

244447:cfap97
gene id: 244447:cfap97
uniprot id: A0A3P8V1G8
names: Similarity
messages: Belongs to the CFAP97 family.

244447:LOC103387249
gene id: 244447:LOC103387249
uniprot id: A0A3P8UWX6
names: Similarity
messages: Belongs to the alpha-actinin family.

244447:LOC103392286
gene id: 244447:LOC103392286
uniprot id: A0A3P8W8K5
names: Similarity
messages: Belongs to the TSC-22/Dip/Bun family.

244447:LOC103381608
gene id: 244447:LOC103381608
uniprot id: A0A3P8VJU2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sesquipedalian family.
messages: Early endosome
messages: Plays a role in endocytic trafficking. Required for receptor recycling from endosomes, both to the trans-Golgi network and the plasma membrane.
messages: Recycling endosome
messages: clathrin-coated vesicle
messages: trans-Golgi network

244447:LOC103385477
gene id: 244447:LOC103385477
uniprot id: A0A3P8WNH2
names: Similarity
messages: Belongs to the galactose-3-O-sulfotransferase family.

244447:treh
gene id: 244447:treh
uniprot id: A0A3P8VDZ7
names: Similarity
messages: Belongs to the glycosyl hydrolase 37 family.

244447:LOC103396229
gene id: 244447:LOC103396229
uniprot id: A0A3P8VN24
names: Similarity
messages: Belongs to the DSD1 family.

244447:LOC103392940
gene id: 244447:LOC103392940
uniprot id: A0A3P8W358
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. Fucose synthase subfamily.
messages: Catalyzes the two-step NADP-dependent conversion of GDP-4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction.

244447:serpine2
gene id: 244447:serpine2
uniprot id: A0A3P8V2U1
names: Similarity
messages: Belongs to the serpin family.

244447:LOC103378165
gene id: 244447:LOC103378165
uniprot id: A0A3P8VRW7
names: Similarity
names: Subunit
messages: Belongs to the 14-3-3 family.
messages: Homodimer, and heterodimer with other family members.

244447:cln8
gene id: 244447:cln8
uniprot id: A0A3P8UA48
names: Subcellular Location Annotation
messages: Membrane

244447:LOC103395630
gene id: 244447:LOC103395630
uniprot id: A0A3P8WY94
names: Subcellular Location Annotation
messages: Membrane

244447:LOC103387234
gene id: 244447:LOC103387234
uniprot id: A0A3P8V2W7
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acid desaturase type 1 family.
messages: Membrane
messages: The histidine box domains are involved in binding the catalytic metal ions.

244447:immp1l
gene id: 244447:immp1l
uniprot id: A0A3P8W8E8
uniprot id: A0A3P8WDQ2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S26 family.
messages: Heterodimer of 2 subunits, IMMPL1 and IMMPL2.
messages: Mitochondrion inner membrane

244447:ngrn
gene id: 244447:ngrn
uniprot id: A0A3P8V010
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the neugrin family.
messages: Forms a regulatory protein-RNA complex, consisting of RCC1L, NGRN, RPUSD3, RPUSD4, TRUB2, FASTKD2 and 16S mt-rRNA. Interacts with 16S mt-rRNA; this interaction is direct.
messages: Mitochondrion membrane
messages: Plays an essential role in mitochondrial ribosome biogenesis. As a component of a functional protein-RNA module, consisting of RCC1L, NGRN, RPUSD3, RPUSD4, TRUB2, FASTKD2 and 16S mitochondrial ribosomal RNA (16S mt-rRNA), controls 16S mt-rRNA abundance and is required for intra-mitochondrial translation of core subunits of the oxidative phosphorylation system.

244447:LOC103395910
gene id: 244447:LOC103395910
uniprot id: A0A3P8W9S4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine beta (chemokine CC) family.
messages: Secreted

244447:LOC103382826
gene id: 244447:LOC103382826
uniprot id: A0A3P8VJC5
names: Subcellular Location Annotation
messages: cytoskeleton

244447:nup205
gene id: 244447:nup205
uniprot id: A0A3P8UQG2
names: Similarity
messages: Belongs to the NUP186/NUP192/NUP205 family.

244447:slc39a11
gene id: 244447:slc39a11
uniprot id: A0A3P8WY04
names: Subcellular Location Annotation
messages: Membrane

244447:LOC103397036
gene id: 244447:LOC103397036
uniprot id: A0A3P8VRB0
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

244447:LOC103389601
gene id: 244447:LOC103389601
uniprot id: A0A3P8V5R8
uniprot id: A0A3P8V5T9
uniprot id: A0A3P8VC52
names: Similarity
messages: Belongs to the inositol 3,4-bisphosphate 4-phosphatase family.

244447:hsd17b4
gene id: 244447:hsd17b4
uniprot id: A0A3P8WMX9
names: Subcellular Location Annotation
messages: Peroxisome

244447:c6hxorf56
gene id: 244447:c6hxorf56
uniprot id: A0A3P8X672
names: Similarity
messages: Belongs to the STEEP1 family.

244447:LOC103391388
gene id: 244447:LOC103391388
uniprot id: A0A3P8W2R8
names: Similarity
messages: Belongs to the cornifelin family.

244447:LOC103387015
gene id: 244447:LOC103387015
uniprot id: A0A3P8ULY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

244447:mpped1
gene id: 244447:mpped1
uniprot id: A0A3P8UXM2
names: Similarity
messages: Belongs to the UPF0046 family.

244447:LOC103384184
gene id: 244447:LOC103384184
uniprot id: A0A3P8W2F6
names: Subcellular Location Annotation
messages: Nucleus

244447:pcdhac2
gene id: 244447:pcdhac2
uniprot id: A0A3P8VT23
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain.

244447:LOC103383213
gene id: 244447:LOC103383213
uniprot id: A0A3P8X0D4
names: Function
names: Similarity
messages: Belongs to the parvalbumin family.
messages: In muscle, parvalbumin is thought to be involved in relaxation after contraction. It binds two calcium ions.

244447:susd5
gene id: 244447:susd5
uniprot id: A0A3P8WK38
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

244447:LOC103397841
gene id: 244447:LOC103397841
uniprot id: A0A3P8X528
names: Subcellular Location Annotation
messages: Membrane

244447:LOC103390851
gene id: 244447:LOC103390851
uniprot id: A0A3P8V068
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

244447:tshz1
gene id: 244447:tshz1
uniprot id: A0A3P8VXD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the teashirt C2H2-type zinc-finger protein family.
messages: Nucleus

244447:nsfl1c
gene id: 244447:nsfl1c
uniprot id: A0A3P8URW8
names: Subcellular Location Annotation
messages: Golgi stack

244447:ppard
gene id: 244447:ppard
uniprot id: A0A3P8URJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

244447:LOC103376883
gene id: 244447:LOC103376883
uniprot id: A0A3P8VFG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Membrane

244447:LOC103393629
gene id: 244447:LOC103393629
uniprot id: A0A3P8W643
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G protein gamma family.
messages: Cell membrane
messages: G proteins are composed of 3 units; alpha, beta and gamma.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

244447:LOC103379087
gene id: 244447:LOC103379087
uniprot id: A0A3P8W2L7
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 4 family.

244447:ftsj3
gene id: 244447:ftsj3
uniprot id: A0A3P8W656
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. SPB1 subfamily.
messages: Interacts with NIP7.
messages: Probable methyltransferase involved in the processing of the 34S pre-rRNA to 18S rRNA and in 40S ribosomal subunit formation.
messages: nucleolus

244447:il1rap
gene id: 244447:il1rap
uniprot id: A0A3P8WLA2
names: Similarity
messages: Belongs to the interleukin-1 receptor family.

244447:tmem115
gene id: 244447:tmem115
uniprot id: A0A3P8V4M6
names: Subcellular Location Annotation
messages: Membrane

244447:papln
gene id: 244447:papln
uniprot id: A0A3P8VL40
names: Subcellular Location Annotation
messages: Membrane

244447:ncam1
gene id: 244447:ncam1
uniprot id: A0A3P8WBF0
uniprot id: A0A3P8WE94
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: This protein is a cell adhesion molecule involved in neuron-neuron adhesion, neurite fasciculation, outgrowth of neurites, etc.

244447:LOC103383228
gene id: 244447:LOC103383228
uniprot id: A0A3P8WYJ4
names: Similarity
messages: Belongs to the AKAP95 family.

244447:mapk8ip3
gene id: 244447:mapk8ip3
uniprot id: A0A3P8W300
names: Similarity
messages: Belongs to the JIP scaffold family.

244447:kcng3
gene id: 244447:kcng3
uniprot id: A0A3P8UZK6
names: Subcellular Location Annotation
messages: Membrane

244447:LOC103385536
gene id: 244447:LOC103385536
uniprot id: A0A3P8WP81
names: Similarity
messages: Belongs to the pellino family.

244447:LOC103391581
gene id: 244447:LOC103391581
uniprot id: A0A3P8UQ63
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c family.
messages: Binds 1 heme group per subunit.
messages: Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.
messages: Mitochondrion intermembrane space

244447:LOC103380384
gene id: 244447:LOC103380384
uniprot id: A0A3P8VGG6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LDH/MDH superfamily. LDH family.
messages: Cytoplasm
messages: Homotetramer.

244447:rpia
gene id: 244447:rpia
uniprot id: A0A3P8W971
names: Similarity
messages: Belongs to the ribose 5-phosphate isomerase family.

244447:LOC103380127
gene id: 244447:LOC103380127
uniprot id: A0A3P8UZZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the carnitine/choline acetyltransferase family.
messages: Membrane
messages: Mitochondrion outer membrane

244447:olfml3
gene id: 244447:olfml3
uniprot id: A0A3P8UTE3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OLFML3 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

244447:LOC103379131
gene id: 244447:LOC103379131
uniprot id: A0A3P8W3H9
names: Similarity
messages: Belongs to the hexokinase family.

244447:LOC103386491
gene id: 244447:LOC103386491
uniprot id: A0A3P8WAL2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

244447:b3gat2
gene id: 244447:b3gat2
uniprot id: A0A3P8UDF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 43 family.
messages: Golgi apparatus membrane
messages: Membrane

244447:ak2
gene id: 244447:ak2
uniprot id: A0A3P8V9Q7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family. AK2 subfamily.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways. Plays a key role in hematopoiesis.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Mitochondrion intermembrane space
messages: Monomer.

244447:LOC103397485
gene id: 244447:LOC103397485
uniprot id: A0A3P8VIY5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transcriptional coactivator PC4 family.
messages: General coactivator that functions cooperatively with TAFs and mediates functional interactions between upstream activators and the general transcriptional machinery. May be involved in stabilizing the multiprotein transcription complex. Binds single-stranded DNA. Also binds, in vitro, non-specifically to double-stranded DNA (ds DNA).
messages: Nucleus

244447:LOC103380113
gene id: 244447:LOC103380113
uniprot id: A0A3P8V7E1
names: Subcellular Location Annotation
messages: Nucleus

244447:LOC103388873
gene id: 244447:LOC103388873
uniprot id: A0A3P8W0A9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
messages: Endoplasmic reticulum

244447:chek1
gene id: 244447:chek1
uniprot id: A0A3P8VNG3
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. NIM1 subfamily.

244447:actl6a
gene id: 244447:actl6a
uniprot id: A0A3P8W3Y1
names: Similarity
messages: Belongs to the actin family.

244447:ctu1
gene id: 244447:ctu1
uniprot id: A0A3P8VSR3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TtcA family. CTU1/NCS6/ATPBD3 subfamily.
messages: Cytoplasm
messages: Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation. It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position.

244447:zdhhc23
gene id: 244447:zdhhc23
uniprot id: A0A3P8WH16
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

244447:rnft1
gene id: 244447:rnft1
uniprot id: A0A3P8VV02
names: Subcellular Location Annotation
messages: Membrane

244447:dlx6
gene id: 244447:dlx6
uniprot id: A0A3P8W3V6
names: Subcellular Location Annotation
messages: Nucleus

244447:LOC103387321
gene id: 244447:LOC103387321
uniprot id: A0A3P8V8F8
names: Subcellular Location Annotation
messages: Membrane

244447:LOC103392507
gene id: 244447:LOC103392507
uniprot id: A0A3P8WZC9
names: Similarity
messages: Belongs to the SCO1/2 family.

244447:dyrk2
gene id: 244447:dyrk2
uniprot id: A0A3P8UXJ1
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MNB/DYRK subfamily.

244447:crygn
gene id: 244447:crygn
uniprot id: A0A3P8WNI4
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

244447:ddb2
gene id: 244447:ddb2
uniprot id: A0A3P8V7Q1
uniprot id: A0A3P8V7Q8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat DDB2/WDR76 family.
messages: Nucleus

244447:LOC103396710
gene id: 244447:LOC103396710
uniprot id: A0A3P8X5F5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GLI C2H2-type zinc-finger protein family.
messages: Nucleus

244447:LOC103389190
gene id: 244447:LOC103389190
uniprot id: A0A3P8WQ57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

244447:LOC103390775
gene id: 244447:LOC103390775
uniprot id: A0A3P8UY91
uniprot id: A0A3P8V6V5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family.
messages: Membrane

244447:LOC103384347
gene id: 244447:LOC103384347
uniprot id: A0A3P8WIN1
uniprot id: A0A3P8WKZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LDB family.
messages: Nucleus

244447:snrpc
gene id: 244447:snrpc
uniprot id: A0A3P8WIQ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the U1 small nuclear ribonucleoprotein C family.
messages: Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. SNRPC/U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region.
messages: Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. snrpc/U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates E complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region.
messages: Nucleus
messages: U1 snRNP is composed of the 7 core Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP, and at least 3 U1 snRNP-specific proteins SNRNP70/U1-70K, SNRPA/U1-A and SNRPC/U1-C. SNRPC/U1-C interacts with U1 snRNA and the 5' splice-site region of the pre-mRNA.

244447:LOC103397861
gene id: 244447:LOC103397861
uniprot id: A0A3P8WYY4
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

244447:parp1
gene id: 244447:parp1
uniprot id: A0A3P8X060
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ARTD/PARP family.
messages: Chromosome
messages: Nucleus
messages: Poly-ADP-ribosyltransferase that mediates poly-ADP-ribosylation of proteins and plays a key role in DNA repair.

244447:LOC103392419
gene id: 244447:LOC103392419
uniprot id: A0A3P8WIT7
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

244447:ccdc153
gene id: 244447:ccdc153
uniprot id: A0A3P8WGJ9
names: Similarity
messages: Belongs to the UPF0610 family.

244447:arhgef11
gene id: 244447:arhgef11
uniprot id: A0A3P8UAD6
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Membrane

244447:LOC103377074
gene id: 244447:LOC103377074
uniprot id: A0A3P8W1S5
names: Similarity
messages: Belongs to the RGS7BP/RGS9BP family.

244447:LOC103388994
gene id: 244447:LOC103388994
uniprot id: A0A3P8WFY9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neurexophilin family.
messages: May be signaling molecules that resemble neuropeptides.
messages: Secreted

244447:nkx2-3
gene id: 244447:nkx2-3
uniprot id: A0A3P8V636
names: Subcellular Location Annotation
messages: Nucleus

244447:rps25
gene id: 244447:rps25
uniprot id: A0A3P8UNV6
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS25 family.

244447:klhl21
gene id: 244447:klhl21
uniprot id: A0A3P8WIZ4
names: Subcellular Location Annotation
messages: spindle

244447:LOC103382782
gene id: 244447:LOC103382782
uniprot id: A0A3P8VGR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

244447:LOC103376815
gene id: 244447:LOC103376815
uniprot id: A0A3P8VGB8
uniprot id: A0A3P8VLJ8
names: Similarity
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. Allantoinase family.
messages: Homotetramer.

244447:LOC103395138
gene id: 244447:LOC103395138
uniprot id: A0A3P8VLW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POU transcription factor family.
messages: Nucleus

244447:c11h12orf10
gene id: 244447:c11h12orf10
uniprot id: A0A3P8VSR4
names: Similarity
messages: Belongs to the MYG1 family.

244447:kcnj15
gene id: 244447:kcnj15
uniprot id: A0A3P8X1P7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.
messages: Membrane

244447:cxxc4
gene id: 244447:cxxc4
uniprot id: A0A3P8UQY4
names: Subcellular Location Annotation
messages: Cytoplasm

244447:LOC103378321
gene id: 244447:LOC103378321
uniprot id: A0A3P8W8G0
uniprot id: A0A3P8WBD1
uniprot id: A0A3P8WDT4
names: Subcellular Location Annotation
messages: Membrane

244447:guk1
gene id: 244447:guk1
uniprot id: A0A3P8VV60
uniprot id: A0A3P8VXX4
names: Similarity
messages: Belongs to the guanylate kinase family.

244447:cnot9
gene id: 244447:cnot9
uniprot id: A0A3P8WG06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CNOT9 family.
messages: P-body

244447:LOC103386186
gene id: 244447:LOC103386186
uniprot id: A0A3P8UY10
uniprot id: A0A3P8V6N4
names: Similarity
messages: Belongs to the TAFA family.

244447:LOC103380769
gene id: 244447:LOC103380769
uniprot id: A0A3P8WYA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family. BCS1 subfamily.
messages: Membrane
messages: Mitochondrion inner membrane

244447:park7
gene id: 244447:park7
uniprot id: A0A3P8X3U3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C56 family.
messages: Membrane raft

244447:LOC103381808
gene id: 244447:LOC103381808
uniprot id: A0A3P8W5S9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ubiA prenyltransferase family.
messages: Converts protoheme IX and farnesyl diphosphate to heme O.
messages: Membrane
messages: Mitochondrion membrane

244447:xpr1
gene id: 244447:xpr1
uniprot id: A0A3P8WB25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SYG1 (TC 2.A.94) family.
messages: Membrane

244447:cops2
gene id: 244447:cops2
uniprot id: A0A3P8VXN1
uniprot id: A0A3P8W605
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSN2 family.
messages: Cytoplasm
messages: Nucleus

244447:mmab
gene id: 244447:mmab
uniprot id: A0A3P8WR06
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

244447:LOC103390935
gene id: 244447:LOC103390935
uniprot id: A0A3P8V982
names: Subcellular Location Annotation
messages: Membrane

244447:LOC103386924
gene id: 244447:LOC103386924
uniprot id: A0A3P8UM26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic mitochondrial porin family.
messages: Mitochondrion outer membrane

244447:LOC103384881
gene id: 244447:LOC103384881
uniprot id: A0A3P8V2C9
names: Similarity
messages: Belongs to the protein kinase superfamily.

244447:tns3
gene id: 244447:tns3
uniprot id: A0A3P8VRG0
names: Similarity
messages: Belongs to the PTEN phosphatase protein family.

244447:cdc5l
gene id: 244447:cdc5l
uniprot id: A0A3P8WNL0
names: Similarity
messages: Belongs to the CEF1 family.

244447:ints9
gene id: 244447:ints9
uniprot id: A0A3P8WT81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. INTS9 subfamily.
messages: Nucleus

244447:phospho2
gene id: 244447:phospho2
uniprot id: A0A3P8V8H1
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. PHOSPHO family.

244447:LOC103383221
gene id: 244447:LOC103383221
uniprot id: A0A3P8X0F0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

244447:rybp
gene id: 244447:rybp
uniprot id: A0A3P8V9U8
names: Subcellular Location Annotation
messages: Nucleus

244447:LOC103377033
gene id: 244447:LOC103377033
uniprot id: A0A3P8VT85
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Cell membrane
messages: Lipid droplet

244447:LOC103391938
gene id: 244447:LOC103391938
uniprot id: A0A3P8V2U3
names: Similarity
messages: Belongs to the small GTPase superfamily. Rab family.

244447:LOC103381754
gene id: 244447:LOC103381754
uniprot id: A0A3P8VXW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NPY family.
messages: Secreted

244447:LOC103383437
gene id: 244447:LOC103383437
uniprot id: A0A3P8UG29
names: Function
messages: Promotes degradation of target mRNA species. Plays a role in the regulation of circadian mRNA stability. Binds GTP and has GTPase activity.

244447:LOC103378647
gene id: 244447:LOC103378647
uniprot id: A0A3P8UGE3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POU transcription factor family.
messages: Nucleus

244447:LOC103384602
gene id: 244447:LOC103384602
uniprot id: A0A3P8UPJ0
names: Similarity
messages: Belongs to the copine family.

244447:sf3a2
gene id: 244447:sf3a2
uniprot id: A0A3P8WCU1
names: Similarity
messages: Belongs to the SF3A2 family.

244447:eif3f
gene id: 244447:eif3f
uniprot id: A0A3P8X3W7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit F family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
messages: Cytoplasm

244447:mrps16
gene id: 244447:mrps16
uniprot id: A0A3P8X3U7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

244447:LOC103395903
gene id: 244447:LOC103395903
uniprot id: A0A3P8W2M3
uniprot id: A0A3P8W5H9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

244447:memo1
gene id: 244447:memo1
uniprot id: A0A3P8W2J7
names: Similarity
messages: Belongs to the MEMO1 family.

244447:LOC103391742
gene id: 244447:LOC103391742
uniprot id: A0A3P8W5X9
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Associates with the cytoplasmic CCR4-NOT deadenylase complex to trigger ARE-containing mRNA deadenylation and decay processes.
messages: Cytoplasm
messages: Nucleus
messages: Zinc-finger RNA-binding protein that destabilizes several cytoplasmic AU-rich element (ARE)-containing mRNA transcripts by promoting their poly(A) tail removal or deadenylation, and hence provide a mechanism for attenuating protein synthesis. Acts as a 3'-untranslated region (UTR) ARE mRNA-binding adapter protein to communicate signaling events to the mRNA decay machinery. Functions by recruiting the CCR4-NOT deadenylase complex and probably other components of the cytoplasmic RNA decay machinery to the bound ARE-containing mRNAs, and hence promotes ARE-mediated mRNA deadenylation and decay processes. Binds to 3'-UTR ARE of numerous mRNAs.

244447:rbx1
gene id: 244447:rbx1
uniprot id: A0A3P8V862
names: Similarity
messages: Belongs to the RING-box family.

244447:KEH01 p04
gene id: 244447:KEH01_p04
uniprot id: C5H0G2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I.
messages: Membrane
messages: Mitochondrion membrane

244447:LOC103381182
gene id: 244447:LOC103381182
uniprot id: A0A3P8UQU8
names: Similarity
messages: Belongs to the actin family.

244447:LOC103385557
gene id: 244447:LOC103385557
uniprot id: A0A3P8WQ21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adaptor complexes small subunit family.
messages: Cytoplasmic vesicle membrane
messages: Golgi apparatus
messages: clathrin-coated pit

244447:yes1
gene id: 244447:yes1
uniprot id: A0A3P8UIW2
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

244447:LOC103378586
gene id: 244447:LOC103378586
uniprot id: A0A3P8WSB9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anoctamin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

244447:mrpl34
gene id: 244447:mrpl34
uniprot id: A0A3P8VVT9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

244447:ins
gene id: 244447:ins
uniprot id: A0A3P8VEB9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the insulin family.
messages: Heterodimer of a B chain and an A chain linked by two disulfide bonds.
messages: Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.
messages: Secreted

244447:polg2
gene id: 244447:polg2
uniprot id: A0A3P8VH35
names: Subcellular Location Annotation
messages: Mitochondrion

244447:LOC103394572
gene id: 244447:LOC103394572
uniprot id: A0A3P8VG25
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

244447:LOC103388309
gene id: 244447:LOC103388309
uniprot id: A0A3P8UR92
uniprot id: A0A3P8UY53
names: Subcellular Location Annotation
messages: Membrane

244447:esrra
gene id: 244447:esrra
uniprot id: A0A3P8VRD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR3 subfamily.
messages: Nucleus

244447:st6galnac5
gene id: 244447:st6galnac5
uniprot id: A0A3P8X6J1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

244447:sugct
gene id: 244447:sugct
uniprot id: A0A3P8WPZ8
names: Similarity
messages: Belongs to the CoA-transferase III family.

244447:LOC103396956
gene id: 244447:LOC103396956
uniprot id: A0A3P8VMR3
names: Similarity
messages: Belongs to the PIAS family.

244447:itgb8
gene id: 244447:itgb8
uniprot id: A0A3P8VHW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin beta chain family.
messages: Membrane

244447:elmo3
gene id: 244447:elmo3
uniprot id: A0A3P8X6B7
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Acts in association with DOCK1 and CRK. Was initially proposed to be required in complex with DOCK1 to activate Rac Rho small GTPases. May enhance the guanine nucleotide exchange factor (GEF) activity of DOCK1.

244447:LOC103388164
gene id: 244447:LOC103388164
uniprot id: A0A3P8URR3
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pentraxin family.
messages: Binds 2 calcium ions per subunit.
messages: Homopentamer. Pentaxin (or pentraxin) have a discoid arrangement of 5 non-covalently bound subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

244447:LOC103392689
gene id: 244447:LOC103392689
uniprot id: A0A3P8X496
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

244447:LOC103392686
gene id: 244447:LOC103392686
uniprot id: A0A3P8X487
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complement C6/C7/C8/C9 family.
messages: Secreted

244447:pou1f1
gene id: 244447:pou1f1
uniprot id: A0A3P8W6F0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POU transcription factor family. Class-1 subfamily.
messages: Nucleus

244447:LOC103385426
gene id: 244447:LOC103385426
uniprot id: A0A3P8X0Y4
names: Similarity
messages: Belongs to the opioid growth factor receptor family.

244447:LOC103381660
gene id: 244447:LOC103381660
uniprot id: A0A3P8VV98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAVIN family.
messages: caveola

244447:LOC103397425
gene id: 244447:LOC103397425
uniprot id: A0A3P8W967
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Membrane

244447:LOC103391400
gene id: 244447:LOC103391400
uniprot id: A0A3P8W5D0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

244447:LOC103399850
gene id: 244447:LOC103399850
uniprot id: A0A3P8URU3
names: Subcellular Location Annotation
messages: cytoskeleton

244447:LOC103384730
gene id: 244447:LOC103384730
uniprot id: A0A3P8UNL0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

244447:thbs3
gene id: 244447:thbs3
uniprot id: A0A3P8UI10
names: Caution
names: Similarity
messages: Belongs to the thrombospondin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

244447:rxfp2
gene id: 244447:rxfp2
uniprot id: A0A0H4ADC9
names: Caution
names: Subcellular Location Annotation
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

244447:hhatl
gene id: 244447:hhatl
uniprot id: A0A3P8WMA2
names: Subcellular Location Annotation
messages: Membrane

244447:LOC103394381
gene id: 244447:LOC103394381
uniprot id: A0A3P8WL32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.
messages: Cytoplasm
messages: Nucleus

244447:sec63
gene id: 244447:sec63
uniprot id: A0A3P8UQL7
names: Subcellular Location Annotation
messages: Membrane

244447:LOC103379551
gene id: 244447:LOC103379551
uniprot id: A0A3P8X2A0
names: Function
names: Similarity
messages: Belongs to the metallothionein superfamily. Type 1 family.
messages: Metallothioneins have a high content of cysteine residues that bind various heavy metals.

244447:kpna1
gene id: 244447:kpna1
uniprot id: A0A3P8WFV2
names: Similarity
messages: Belongs to the importin alpha family.

244447:LOC103394101
gene id: 244447:LOC103394101
uniprot id: A0A3P8VVA1
names: Subcellular Location Annotation
messages: Nucleus

244447:LOC103386108
gene id: 244447:LOC103386108
uniprot id: A0A3P8UWK8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone deacetylase family. HD type 2 subfamily.
messages: Nucleus
messages: Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.

244447:mrpl3
gene id: 244447:mrpl3
uniprot id: A0A3P8VJE2
names: Similarity
messages: Belongs to the universal ribosomal protein uL3 family.

244447:LOC103385067
gene id: 244447:LOC103385067
uniprot id: A0A3P8V5D2
names: Similarity
messages: Belongs to the EPS8 family.

244447:plod2
gene id: 244447:plod2
uniprot id: A0A3P8WA88
uniprot id: A0A3P8WDA8
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane

244447:des
gene id: 244447:des
uniprot id: A0A3P8V4W7
names: Similarity
messages: Belongs to the intermediate filament family.

244447:LOC103382566
gene id: 244447:LOC103382566
uniprot id: A0A3P8UXP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

244447:atp6v1d
gene id: 244447:atp6v1d
uniprot id: A0A3P8URE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase D subunit family.
messages: clathrin-coated vesicle membrane

244447:vps4b
gene id: 244447:vps4b
uniprot id: A0A3P8WS45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family.
messages: Late endosome membrane

244447:LOC103389019
gene id: 244447:LOC103389019
uniprot id: A0A3P8WBB5
names: Similarity
messages: Belongs to the glycosyl hydrolase 47 family.

244447:LOC103380084
gene id: 244447:LOC103380084
uniprot id: A0A3P8V0A8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 3 family.
messages: Cell membrane
messages: G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling inhibits adenylate cyclase activity.
messages: Interacts with TAMALIN.
messages: Membrane

244447:rara
gene id: 244447:rara
uniprot id: A0A344X2U5
uniprot id: A0A3P8W341
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Heterodimer; with an rxr molecule. Binds DNA preferentially as a rar/rxr heterodimer.
messages: Nucleus

244447:mapk6
gene id: 244447:mapk6
uniprot id: A0A3P8VZ14
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.

244447:LOC103392411
gene id: 244447:LOC103392411
uniprot id: A0A3P8WI12
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

244447:vps29
gene id: 244447:vps29
uniprot id: A0A3P8W8S3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway.
messages: Belongs to the VPS29 family.
messages: Endosome membrane

244447:LOC103387511
gene id: 244447:LOC103387511
uniprot id: A0A3P8VT38
names: Similarity
messages: Belongs to the PRORSD1 family.

244447:tshz2
gene id: 244447:tshz2
uniprot id: A0A3P8VSS1
names: Similarity
messages: Belongs to the teashirt C2H2-type zinc-finger protein family.

244447:l3mbtl3
gene id: 244447:l3mbtl3
uniprot id: A0A3P8UQI0
names: Subcellular Location Annotation
messages: Nucleus

244447:arcn1
gene id: 244447:arcn1
uniprot id: A0A3P8V101
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adaptor complexes medium subunit family. Delta-COP subfamily.
messages: COPI-coated vesicle membrane
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Membrane
messages: Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.
messages: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.

244447:LOC103377857
gene id: 244447:LOC103377857
uniprot id: A0A3P8US59
names: Similarity
messages: Belongs to the HEBP family.

244447:atp5pf
gene id: 244447:atp5pf
uniprot id: A0A3P8VX28
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic ATPase subunit F6 family.
messages: Membrane
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain and the peripheric stalk, which acts as a stator to hold the catalytic alpha(3)beta(3) subcomplex and subunit a/ATP6 static relative to the rotary elements. Also involved in the restoration of oligomycin-sensitive ATPase activity to depleted F1-F0 complexes.
messages: Mitochondrion
messages: Mitochondrion inner membrane

244447:LOC103395301
gene id: 244447:LOC103395301
uniprot id: A0A3P8W9X6
names: Subcellular Location Annotation
messages: Membrane
messages: cytoskeleton

244447:LOC103393114
gene id: 244447:LOC103393114
uniprot id: A0A3P8WE49
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

244447:LOC103388698
gene id: 244447:LOC103388698
uniprot id: A0A3P8VKS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CUT homeobox family.
messages: Nucleus

244447:mtfr1l
gene id: 244447:mtfr1l
uniprot id: A0A3P8UT96
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MTFR1 family.
messages: Mitochondrion
messages: Plays a role in mitochondrial aerobic respiration. Regulates mitochondrial organization and fission.

244447:mfsd11
gene id: 244447:mfsd11
uniprot id: A0A3P8VVY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the unc-93 family.
messages: Membrane

244447:psmd7
gene id: 244447:psmd7
uniprot id: A0A3P8V489
names: Similarity
messages: Belongs to the peptidase M67A family.

244447:smg9
gene id: 244447:smg9
uniprot id: A0A3P8V278
names: Similarity
messages: Belongs to the SMG9 family.

244447:popdc3
gene id: 244447:popdc3
uniprot id: A0A3P8W3S3
names: Similarity
messages: Belongs to the popeye family.

244447:LOC103395289
gene id: 244447:LOC103395289
uniprot id: A0A3P8W1P2
names: Similarity
messages: Belongs to the Amer family.

244447:wnt7a
gene id: 244447:wnt7a
uniprot id: A0A3P8X129
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

244447:tppp
gene id: 244447:tppp
uniprot id: A0A3P8V1Q1
uniprot id: A0A3P8V3M0
names: Similarity
messages: Belongs to the TPPP family.

244447:psmd1
gene id: 244447:psmd1
uniprot id: A0A3P8WCI6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the proteasome subunit S1 family.
messages: Component of the 19S proteasome regulatory particle complex. The 26S proteasome consists of a 20S core particle (CP) and two 19S regulatory subunits (RP).
messages: Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair.

244447:msrb2
gene id: 244447:msrb2
uniprot id: A0A3P8VCR5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Binds 1 zinc ion per subunit.
messages: Methionine-sulfoxide reductase that specifically reduces methionine (R)-sulfoxide back to methionine. While in many cases methionine oxidation is the result of random oxidation following oxidative stress, methionine oxidation is also a post-translational modification that takes place on specific residues.

244447:nt5dc1
gene id: 244447:nt5dc1
uniprot id: A0A3P8WG17
names: Similarity
messages: Belongs to the 5'(3')-deoxyribonucleotidase family.

244447:cops9
gene id: 244447:cops9
uniprot id: A0A3P8WRQ4
names: Similarity
messages: Belongs to the CSN9 family.

244447:LOC103398249
gene id: 244447:LOC103398249
uniprot id: A0A3P8WB62
names: Similarity
messages: Belongs to the carotenoid oxygenase family.

244447:LOC103382928
gene id: 244447:LOC103382928
uniprot id: A0A3P8WBC0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the organo anion transporter (TC 2.A.60) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

244447:srp72
gene id: 244447:srp72
uniprot id: A0A3P8UZC4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SRP72 family.
messages: Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER).
messages: Cytoplasm

244447:LOC103393166
gene id: 244447:LOC103393166
uniprot id: A0A3P8WHH6
uniprot id: A0A3P8WKE0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase 116 kDa subunit family.
messages: Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.
messages: Membrane

244447:LOC103394124
gene id: 244447:LOC103394124
uniprot id: A0A3P8W0N2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argonaute family. Ago subfamily.
messages: Component of the RISC loading complex (RLC), or micro-RNA (miRNA) loading complex (miRLC), which is composed of dicer1, ago2 and tarbp2. Note that the trimeric RLC/miRLC is also referred to as RISC.
messages: P-body
messages: Required for RNA-mediated gene silencing (RNAi) by the RNA-induced silencing complex (RISC). The 'minimal RISC' appears to include ago2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the mRNA specifically by ago2. Binding of RISC to a partially complementary mRNA results in silencing through inhibition of translation, and this is independent of endonuclease activity. The inhibition of translational initiation leads to the accumulation of the affected mRNA in cytoplasmic processing bodies (P-bodies), where mRNA degradation may subsequently occur.
messages: The Piwi domain may perform RNA cleavage by a mechanism similar to that of RNase H. However, while RNase H utilizes a triad of Asp-Asp-Glu (DDE) for metal ion coordination, this protein appears to utilize a triad of Asp-Asp-His (DDH).

244447:LOC103392734
gene id: 244447:LOC103392734
uniprot id: A0A3P8X6P5
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

244447:kdm1a
gene id: 244447:kdm1a
uniprot id: A0A3P8UUK2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the flavin monoamine oxidase family.
messages: Histone demethylase that can demethylate both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me. May play a role in the repression of neuronal genes. Alone, it is unable to demethylate H3K4me on nucleosomes and requires the presence of RCOR1/CoREST to achieve such activity.
messages: Nucleus
messages: The SWIRM domain may act as an anchor site for a histone tail.

244447:plagl2
gene id: 244447:plagl2
uniprot id: A0A3P8WX94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the krueppel C2H2-type zinc-finger protein family.
messages: Nucleus

244447:traf4
gene id: 244447:traf4
uniprot id: A0A3P8W0T8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TNF receptor-associated factor family.
messages: Cytoplasm

244447:LOC103379984
gene id: 244447:LOC103379984
uniprot id: A0A3P8UV98
names: Subcellular Location Annotation
messages: Membrane

244447:dus4l
gene id: 244447:dus4l
uniprot id: A0A3P8WUS4
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs.

244447:LOC103389225
gene id: 244447:LOC103389225
uniprot id: A0A3P8UHA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Membrane
messages: trans-Golgi network membrane

244447:LOC103394790
gene id: 244447:LOC103394790
uniprot id: A0A3P8VV23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WSCD family.
messages: Membrane

244447:mlnr
gene id: 244447:mlnr
uniprot id: A0A3P8VDF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

244447:srsf2
gene id: 244447:srsf2
uniprot id: A0A3P8W367
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the splicing factor SR family.
messages: Nucleus

244447:mapk7
gene id: 244447:mapk7
uniprot id: A0A3P8WUZ4
names: Activity Regulation
names: Similarity
messages: Activated by threonine and tyrosine phosphorylation.
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.

244447:LOC103394706
gene id: 244447:LOC103394706
uniprot id: A0A3P8VPL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 99 family.
messages: Golgi apparatus membrane
messages: Membrane

244447:LOC103393771
gene id: 244447:LOC103393771
uniprot id: A0A3P8WNJ1
names: Similarity
messages: Belongs to the WD repeat G protein beta family.

244447:LOC103386032
gene id: 244447:LOC103386032
uniprot id: A0A3P8V1L9
names: Similarity
messages: Belongs to the JARID1 histone demethylase family.

244447:pex3
gene id: 244447:pex3
uniprot id: A0A3P8V3A6
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Interacts with PEX19.
messages: Involved in peroxisome biosynthesis and integrity. Assembles membrane vesicles before the matrix proteins are translocated. As a docking factor for PEX19, is necessary for the import of peroxisomal membrane proteins in the peroxisomes.
messages: Peroxisome membrane

244447:lpl
gene id: 244447:lpl
uniprot id: A0A0H3WGF9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AB hydrolase superfamily. Lipase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

244447:LOC103396041
gene id: 244447:LOC103396041
uniprot id: A0A3P8WFG6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IL-6 superfamily.
messages: Heterodimer with IL12B; disulfide-linked. The heterodimer is known as interleukin IL-12.
messages: Secreted

244447:dpyd
gene id: 244447:dpyd
uniprot id: A0A3P8WRN0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the dihydropyrimidine dehydrogenase family.
messages: Binds 4 [4Fe-4S] clusters. Contains approximately 16 iron atoms per subunit.
messages: Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine.

244447:LOC103391500
gene id: 244447:LOC103391500
uniprot id: A0A3P8X3J3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family.
messages: Membrane

244447:kcnj5
gene id: 244447:kcnj5
uniprot id: A0A3P8UMK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.
messages: Membrane

244447:LOC103377359
gene id: 244447:LOC103377359
uniprot id: A0A3P8WS51
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

244447:bsg
gene id: 244447:bsg
uniprot id: A0A3P8ULS8
uniprot id: A0A3P8UQN0
names: Subcellular Location Annotation
messages: Basolateral cell membrane
messages: Cell membrane
messages: Endoplasmic reticulum membrane
messages: Lateral cell membrane
messages: Membrane

244447:alpl
gene id: 244447:alpl
uniprot id: A0A3P8W4M6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alkaline phosphatase family.
messages: Cell membrane
messages: Membrane

244447:batf
gene id: 244447:batf
uniprot id: A0A3P8WZ40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family.
messages: Cytoplasm

244447:gatb
gene id: 244447:gatb
uniprot id: A0A3P8V171
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Mitochondrion
messages: Subunit of the heterotrimeric GatCAB amidotransferase (AdT) complex, composed of A (QRSL1), B (GATB) and C (GATC) subunits.

244447:LOC103394984
gene id: 244447:LOC103394984
uniprot id: A0A3P8WT49
names: Similarity
messages: Belongs to the PP1 inhibitor family.

244447:LOC103383908
gene id: 244447:LOC103383908
uniprot id: A0A3P8VT18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

244447:lta4h
gene id: 244447:lta4h
uniprot id: A0A3P8V5I0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm

244447:LOC103397813
gene id: 244447:LOC103397813
uniprot id: A0A3P8WUC8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for NPAF (A-18-F-amide) and NPFF (F-8-F-amide) neuropeptides, also known as morphine-modulating peptides. Can also be activated by a variety of naturally occurring or synthetic FMRF-amide like ligands. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.

244447:LOC103386703
gene id: 244447:LOC103386703
uniprot id: A0A3P8WVS8
names: Subcellular Location Annotation
messages: Membrane
messages: dendrite

244447:cct6a
gene id: 244447:cct6a
uniprot id: A0A3P8WW62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCP-1 chaperonin family.
messages: Cytoplasm

244447:ca6
gene id: 244447:ca6
uniprot id: A0A3P8V4G0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alpha-carbonic anhydrase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reversible hydration of carbon dioxide. Its role in saliva is unknown.
messages: Secreted

244447:LOC103379201
gene id: 244447:LOC103379201
uniprot id: A0A3P8V8A6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endophilin family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Membrane

244447:LOC103397930
gene id: 244447:LOC103397930
uniprot id: A0A3P8VHP0
names: Subcellular Location Annotation
messages: Secreted
messages: Synapse

244447:LOC103395974
gene id: 244447:LOC103395974
uniprot id: A0A3P8W9J8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine beta (chemokine CC) family.
messages: Secreted

244447:rad51
gene id: 244447:rad51
uniprot id: A0A3P8WK87
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family. RAD51 subfamily.
messages: Nucleus
messages: Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination (HR). Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Recruited to resolve stalled replication forks during replication stress. Also involved in interstrand cross-link repair.

244447:LOC103391218
gene id: 244447:LOC103391218
uniprot id: A0A3P8WE64
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.

244447:LOC103397565
gene id: 244447:LOC103397565
uniprot id: A0A3P8WHR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NTE family.
messages: Endoplasmic reticulum membrane
messages: Membrane

244447:hs3st6
gene id: 244447:hs3st6
uniprot id: A0A3P8WGC7
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

244447:LOC103398194
gene id: 244447:LOC103398194
uniprot id: A0A3P8WC09
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the aldo/keto reductase family.
messages: Cell membrane
messages: Membrane
messages: cytosol

244447:LOC103390609
gene id: 244447:LOC103390609
uniprot id: A0A3P8UXK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. Aurora subfamily.
messages: Chromosome

244447:tmem199
gene id: 244447:tmem199
uniprot id: A0A3P8V6A8
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

244447:stx10
gene id: 244447:stx10
uniprot id: A0A3P8X3R5
names: Subcellular Location Annotation
messages: Golgi apparatus membrane

244447:idh3g
gene id: 244447:idh3g
uniprot id: A0A3P8UFX7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Heterooligomer of subunits alpha (IDH3A), beta (IDH3B), and gamma (IDH3G) in the apparent ratio of 2:1:1. The heterodimer containing one IDH3A and one IDH3B subunit and the heterodimer containing one IDH3A and one IDH3G subunit assemble into a heterotetramer (which contains two subunits of IDH3A, one of IDH3B and one of IDH3G) and further into the heterooctamer.
messages: Mitochondrion

244447:LOC103395594
gene id: 244447:LOC103395594
uniprot id: A0A3P8WP47
names: Similarity
messages: Belongs to the JHDM3 histone demethylase family.

244447:LOC103389708
gene id: 244447:LOC103389708
uniprot id: A0A3P8VTV2
names: Similarity
messages: Belongs to the MAGUK family.

244447:LOC103395405
gene id: 244447:LOC103395405
uniprot id: A0A3P8WJP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L6 tetraspanin family.
messages: Membrane

244447:LOC103396868
gene id: 244447:LOC103396868
uniprot id: A0A3P8VBB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPRING family.
messages: Golgi apparatus membrane
messages: Membrane

244447:LOC103385801
gene id: 244447:LOC103385801
uniprot id: A0A3P8UJJ4
names: Subcellular Location Annotation
messages: cytoskeleton

244447:LOC103379871
gene id: 244447:LOC103379871
uniprot id: A0A3P8UGD1
names: Similarity
messages: Belongs to the glycosyl hydrolase 56 family.

244447:gpr34
gene id: 244447:gpr34
uniprot id: A0A3P8VZH5
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

244447:pde4b
gene id: 244447:pde4b
uniprot id: A0A3P8WKT0
uniprot id: A0A3P8WLC4
uniprot id: A0A3P8WRM0
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family. PDE4 subfamily.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

244447:LOC103390062
gene id: 244447:LOC103390062
uniprot id: A0A3P8W706
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Elbow/Noc family.
messages: Nucleus

244447:uchl1
gene id: 244447:uchl1
uniprot id: A0A3P8UX95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C12 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

244447:spr
gene id: 244447:spr
uniprot id: A0A3P8WW18
names: Similarity
messages: Belongs to the sepiapterin reductase family.

244447:caprin1
gene id: 244447:caprin1
uniprot id: A0A3P8W7L2
names: Similarity
messages: Belongs to the caprin family.

244447:peli2
gene id: 244447:peli2
uniprot id: A0A3P8UD90
uniprot id: A0A3P8UID8
names: Similarity
messages: Belongs to the pellino family.

244447:xpot
gene id: 244447:xpot
uniprot id: A0A3P8USI2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exportin family.
messages: Cytoplasm
messages: Nucleus
messages: tRNA nucleus export receptor which facilitates tRNA translocation across the nuclear pore complex.

244447:oxsm
gene id: 244447:oxsm
uniprot id: A0A3P8WJ71
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

244447:LOC103378038
gene id: 244447:LOC103378038
uniprot id: A0A3P8VA56
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFC2 subunit family.
messages: Mitochondrion inner membrane

244447:LOC103388329
gene id: 244447:LOC103388329
uniprot id: A0A3P8USH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/IRO homeobox family.
messages: Nucleus

244447:LOC103389976
gene id: 244447:LOC103389976
uniprot id: A0A3P8W4G3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic mitochondrial porin family.
messages: Forms a channel through the mitochondrial outer membrane that allows diffusion of small hydrophilic molecules.
messages: Interacts with ARMC12 in a TBC1D21-dependent manner.
messages: Mitochondrion outer membrane

244447:fshr
gene id: 244447:fshr
uniprot id: B2ZGP6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Basolateral cell membrane
messages: Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily.
messages: Cell membrane
messages: G protein-coupled receptor for follitropin, the follicle-stimulating hormone. Through cAMP production activates the downstream PI3K-AKT and ERK1/ERK2 signaling pathways.
messages: Membrane
messages: Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a central role in controlling thyroid cell metabolism.

244447:LOC107989854
gene id: 244447:LOC107989854
uniprot id: A0A3P8WHA6
names: Subcellular Location Annotation
messages: Nucleus

244447:LOC103392763
gene id: 244447:LOC103392763
uniprot id: A0A3P8V6L8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SFT2 family.
messages: May be involved in fusion of retrograde transport vesicles derived from an endocytic compartment with the Golgi complex.
messages: Membrane

244447:LOC103392536
gene id: 244447:LOC103392536
uniprot id: A0A3P8WXH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. PAR subfamily.
messages: Nucleus

244447:bco2
gene id: 244447:bco2
uniprot id: A0A3P8UZ57
names: Similarity
messages: Belongs to the carotenoid oxygenase family.

244447:LOC103397669
gene id: 244447:LOC103397669
uniprot id: A0A3P8WJZ9
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

244447:snx7
gene id: 244447:snx7
uniprot id: A0A3P8VEG9
names: Similarity
messages: Belongs to the sorting nexin family.

244447:ano10
gene id: 244447:ano10
uniprot id: A0A3P8VR31
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anoctamin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

244447:LOC103388117
gene id: 244447:LOC103388117
uniprot id: A0A3P8UI86
names: Similarity
messages: Belongs to the ANP32 family.

244447:LOC103385177
gene id: 244447:LOC103385177
uniprot id: A0A3P8VLW3
uniprot id: A0A3P8VPU8
names: Similarity
names: Subunit
messages: Homodimer.
messages: In the C-terminal section; belongs to the phosphoglycerate mutase family.

244447:LOC103389513
gene id: 244447:LOC103389513
uniprot id: A0A3P8V286
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the shroom family.
messages: cytoskeleton

244447:LOC103391605
gene id: 244447:LOC103391605
uniprot id: A0A3P8WDA0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SLX1 family.
messages: Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA.
messages: Forms a heterodimer with SLX4.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

244447:aldh8a1
gene id: 244447:aldh8a1
uniprot id: A0A3P8UMF4
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

244447:llgl1
gene id: 244447:llgl1
uniprot id: A0A3P8WT64
names: Similarity
messages: Belongs to the WD repeat L(2)GL family.

244447:LOC103396898
gene id: 244447:LOC103396898
uniprot id: A0A3P8VA23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-1 family.
messages: Lysosome
messages: cytosol
messages: extracellular exosome

244447:adsl
gene id: 244447:adsl
uniprot id: A0A3P8V5H0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
messages: Catalyzes two non-sequential steps in de novo AMP synthesis: converts (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate (SAICAR) to fumarate plus 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide, and thereby also contributes to de novo IMP synthesis, and converts succinyladenosine monophosphate (SAMP) to AMP and fumarate.
messages: Homotetramer. Residues from neighboring subunits contribute catalytic and substrate-binding residues to each active site.

244447:LOC103381118
gene id: 244447:LOC103381118
uniprot id: A0A3P8US08
uniprot id: A0A3P8UTK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dystrophin family. Dystrobrevin subfamily.
messages: Cytoplasm

244447:LOC103391312
gene id: 244447:LOC103391312
uniprot id: A0A3P8WT04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.
messages: Cytoplasm

244447:ctgf
gene id: 244447:ctgf
uniprot id: A0A3P8WRR1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCN family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

244447:dhrs1
gene id: 244447:dhrs1
uniprot id: A0A3P8X1R7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

244447:LOC103391564
gene id: 244447:LOC103391564
uniprot id: A0A3P8UPI3
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: The potassium channel is probably composed of a homo- or heterotetrameric complex of pore-forming alpha subunits that can associate with modulating beta subunits.

244447:LOC103378006
gene id: 244447:LOC103378006
uniprot id: A0A3P8V8R0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

244447:LOC103385502
gene id: 244447:LOC103385502
uniprot id: A0A3P8X347
names: Similarity
messages: Belongs to the peptidase A1 family.

244447:vwc2
gene id: 244447:vwc2
uniprot id: A0A3P8VJN9
names: Subcellular Location Annotation
messages: Synapse

244447:pigs
gene id: 244447:pigs
uniprot id: A0A3P8VJL8
uniprot id: A0A3P8VSQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGS family.
messages: Endoplasmic reticulum membrane
messages: Membrane

244447:LOC103384165
gene id: 244447:LOC103384165
uniprot id: A0A3P8W1U2
uniprot id: A0A3P8W4D8
uniprot id: A0A3P8W4F1
uniprot id: A0A3P8W715
uniprot id: A0A3P8W725
uniprot id: A0A3P8W763
uniprot id: A0A3P8WA85
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CTF/NF-I family.
messages: Binds DNA as a homodimer.
messages: Nucleus
messages: Recognizes and binds the palindromic sequence 5'-TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication.

244447:LOC103383985
gene id: 244447:LOC103383985
uniprot id: A0A3P8VMG0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMDT1/EMRE family.
messages: Component of the uniplex complex. Interacts (via the transmembrane region) with MCU (via the first transmembrane region); the interaction is direct.
messages: Essential regulatory subunit of the mitochondrial calcium uniporter complex (uniplex), a complex that mediates calcium uptake into mitochondria.
messages: Membrane
messages: Mitochondrion inner membrane

244447:rpl27
gene id: 244447:rpl27
uniprot id: A0A3P8X0R0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic ribosomal protein eL27 family.
messages: Endoplasmic reticulum

244447:cpe
gene id: 244447:cpe
uniprot id: A0A3P8VTP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M14 family.
messages: Membrane
messages: secretory vesicle membrane

244447:emx2
gene id: 244447:emx2
uniprot id: A0A3P8VEH7
names: Subcellular Location Annotation
messages: Nucleus

244447:LOC103395522
gene id: 244447:LOC103395522
uniprot id: A0A3P8WZG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Cell membrane
messages: Membrane

244447:vegfa
gene id: 244447:vegfa
uniprot id: A0A3P8X187
names: Similarity
messages: Belongs to the PDGF/VEGF growth factor family.

244447:LOC103381207
gene id: 244447:LOC103381207
uniprot id: A0A3P8UYQ4
names: Similarity
messages: Belongs to the splicing factor SR family.

244447:LOC103388270
gene id: 244447:LOC103388270
uniprot id: A0A3P8UQD2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.
messages: Membrane

244447:wnt11
gene id: 244447:wnt11
uniprot id: A0A3P8W7D5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

244447:nmb
gene id: 244447:nmb
uniprot id: A0A3P8VXW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bombesin/neuromedin-B/ranatensin family.
messages: Secreted

244447:clta
gene id: 244447:clta
uniprot id: A0A3P8VY18
uniprot id: A0A3P8VY23
uniprot id: A0A3P8W6G5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the clathrin light chain family.
messages: Clathrin is the major protein of the polyhedral coat of coated pits and vesicles.
messages: Cytoplasmic vesicle membrane
messages: coated pit

244447:nmt1
gene id: 244447:nmt1
uniprot id: A0A3P8VND2
names: Function
names: Similarity
messages: Adds a myristoyl group to the N-terminal glycine residue of certain cellular proteins.
messages: Belongs to the NMT family.

244447:idnk
gene id: 244447:idnk
uniprot id: A0A3P8W1C3
names: Similarity
messages: Belongs to the gluconokinase GntK/GntV family.

244447:ap4s1
gene id: 244447:ap4s1
uniprot id: A0A3P8VU14
names: Similarity
messages: Belongs to the adaptor complexes small subunit family.

244447:sec11a
gene id: 244447:sec11a
uniprot id: A0A3P8VXP3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S26B family.
messages: Component of the signal peptidase complex.
messages: Endoplasmic reticulum membrane
messages: Membrane

244447:il17f
gene id: 244447:il17f
uniprot id: A0A3P8WUJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-17 family.
messages: Secreted

244447:LOC103378333
gene id: 244447:LOC103378333
uniprot id: A0A3P8WHF6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the somatostatin family.
messages: Secreted
messages: Somatostatin inhibits the release of somatotropin.

244447:pan3
gene id: 244447:pan3
uniprot id: A0A3P8WG83
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the protein kinase superfamily. PAN3 family.
messages: Contains a pseudokinase domain. The protein kinase domain is predicted to be catalytically inactive because some of the residues important for catalytic activity are substituted and it lacks the equivalent of the binding site for a peptide substrate. However, it has retained an ATP-binding site and ATP-binding is required for mRNA degradation, stimulating the activity of the PAN2 nuclease in vitro. The nucleotide-binding site is juxtaposed to the RNase active site of PAN2 in the complex and may actually bind nucleosides of a poly(A) RNA rather than ATP, feeding the poly(A)-tail to the active site of the deadenylase and thus increasing the efficiency with which this distributive enzyme degrades oligo(A) RNAs.
messages: Homodimer. Forms a heterotrimer with a catalytic subunit PAN2 to form the poly(A)-nuclease (PAN) deadenylation complex. Interacts (via PAM-2 motif) with poly(A)-binding protein PABPC1 (via PABC domain), conferring substrate specificity of the enzyme complex. Interacts with the GW182 family proteins TNRC6A, TNRC6B and TNRC6C.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: P-body
messages: Regulatory subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in general and miRNA-mediated mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein (PABP). PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent 5'-3' exonucleolytic degradation by XRN1. PAN3 acts as a positive regulator for PAN activity, recruiting the catalytic subunit PAN2 to mRNA via its interaction with RNA and PABP, and to miRNA targets via its interaction with GW182 family proteins.
messages: The N-terminal zinc finger binds to poly(A) RNA.
messages: The pseudokinase domain, the coiled-coil (CC), and C-terminal knob domain (CK) form a structural unit (PKC) that forms an extensive high-affinity interaction surface for PAN2.

244447:LOC103380837
gene id: 244447:LOC103380837
uniprot id: A0A3P8X392
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POMC family.
messages: Secreted
messages: Stimulates the adrenal glands to release cortisol.

244447:heatr5a
gene id: 244447:heatr5a
uniprot id: A0A3P8VXN0
names: Similarity
messages: Belongs to the HEATR5 family.

244447:LOC103386276
gene id: 244447:LOC103386276
uniprot id: A0A3P8VHF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.
messages: Cell membrane
messages: Membrane

244447:nop14
gene id: 244447:nop14
uniprot id: A0A3P8X081
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOP14 family.
messages: Involved in nucleolar processing of pre-18S ribosomal RNA. Has a role in the nuclear export of 40S pre-ribosomal subunit to the cytoplasm.
messages: nucleolus

244447:mfsd6l
gene id: 244447:mfsd6l
uniprot id: A0A3P8W5K8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. MFSD6 family.
messages: Membrane

244447:atl1
gene id: 244447:atl1
uniprot id: A0A3P8VC17
uniprot id: A0A3P8VCI6
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3 GTPase family.

244447:prpf18
gene id: 244447:prpf18
uniprot id: A0A3P8V8C9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRP18 family.
messages: Nucleus speckle

244447:psmc1
gene id: 244447:psmc1
uniprot id: A0A3P8WRZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family.
messages: Cytoplasm
messages: Nucleus

244447:LOC103386600
gene id: 244447:LOC103386600
uniprot id: A0A3P8WIW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

244447:LOC103379657
gene id: 244447:LOC103379657
uniprot id: A0A3P8X3Q1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cyclin family. Cyclin AB subfamily.
messages: Belongs to the cyclin family. Cyclin D subfamily.
messages: Cytoplasm
messages: Essential for the control of the cell cycle at the G2/M (mitosis) transition.
messages: Interacts with the CDK1 protein kinase to form a serine/threonine kinase holoenzyme complex also known as maturation promoting factor (MPF). The cyclin subunit imparts substrate specificity to the complex.
messages: Nucleus

244447:srp9
gene id: 244447:srp9
uniprot id: A0A3P8WQP9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SRP9 family.
messages: Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER). SRP9 together with SRP14 and the Alu portion of the SRP RNA, constitutes the elongation arrest domain of SRP. The complex of SRP9 and SRP14 is required for SRP RNA binding.
messages: Cytoplasm

244447:dnph1
gene id: 244447:dnph1
uniprot id: A0A3P8V1J5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 family.
messages: Catalyzes the cleavage of the N-glycosidic bond of deoxyribonucleoside 5'-monophosphates to yield deoxyribose 5-phosphate and a purine or pyrimidine base. Deoxyribonucleoside 5'-monophosphates containing purine bases are preferred to those containing pyrimidine bases.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer and homodimer.
messages: Nucleus

244447:LOC103379822
gene id: 244447:LOC103379822
uniprot id: A0A3P8UDZ0
names: Similarity
messages: Belongs to the PPP1R15 family.

244447:LOC103378288
gene id: 244447:LOC103378288
uniprot id: A0A3P8W7G0
names: Similarity
messages: Belongs to the heat shock protein 70 family.

244447:LOC103381410
gene id: 244447:LOC103381410
uniprot id: A0A3P8VBL2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family.
messages: Cytoplasm

244447:c11h1orf74
gene id: 244447:c11h1orf74
uniprot id: A0A3P8UI99
names: Similarity
messages: Belongs to the UPF0739 family.

244447:pax9
gene id: 244447:pax9
uniprot id: A0A3P8VC58
names: Subcellular Location Annotation
messages: Nucleus

244447:LOC103393533
gene id: 244447:LOC103393533
uniprot id: A0A3P8UAG6
names: Caution
names: Similarity
messages: Belongs to the thrombospondin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

244447:LOC103385173
gene id: 244447:LOC103385173
uniprot id: A0A3P8VMB7
names: Similarity
messages: Belongs to the vacuolar ATPase subunit S1 family.

244447:LOC103384185
gene id: 244447:LOC103384185
uniprot id: A0A3P8W5B2
names: Subcellular Location Annotation
messages: Nucleus

244447:kirrel2
gene id: 244447:kirrel2
uniprot id: A0A3P8VB83
names: Subcellular Location Annotation
messages: Membrane

244447:vps53
gene id: 244447:vps53
uniprot id: A0A3P8WPU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS53 family.
messages: Endosome membrane
messages: Membrane
messages: trans-Golgi network membrane

244447:LOC103394960
gene id: 244447:LOC103394960
uniprot id: A0A3P8WHN3
names: Subcellular Location Annotation
messages: Membrane

244447:gns
gene id: 244447:gns
uniprot id: A0A3P8VDZ4
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfatase family.
messages: Lysosome
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

244447:LOC103388207
gene id: 244447:LOC103388207
uniprot id: A0A3P8UKQ8
names: Similarity
messages: Belongs to the proteasome subunit S5A family.

244447:LOC103385431
gene id: 244447:LOC103385431
uniprot id: A0A3P8X041
names: Similarity
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.

244447:snd1
gene id: 244447:snd1
uniprot id: A0A3P8VLX0
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Endonuclease that mediates miRNA decay of both protein-free and AGO2-loaded miRNAs.

244447:LOC103397478
gene id: 244447:LOC103397478
uniprot id: A0A3P8VK86
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

244447:LOC103397848
gene id: 244447:LOC103397848
uniprot id: A0A3P8X5X8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GATS family.
messages: cytosol

244447:LOC103386207
gene id: 244447:LOC103386207
uniprot id: A0A3P8V3Y8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neurexin family.
messages: Belongs to the syndecan proteoglycan family.
messages: Cell surface proteoglycan.
messages: Membrane

244447:LOC103387408
gene id: 244447:LOC103387408
uniprot id: A0A3P8VJ03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sphingomyelin synthase family.
messages: Membrane

244447:rer1
gene id: 244447:rer1
uniprot id: A0A3P8WR14
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RER1 family.
messages: Involved in the retrieval of endoplasmic reticulum membrane proteins from the early Golgi compartment.
messages: Membrane

244447:LOC103377018
gene id: 244447:LOC103377018
uniprot id: A0A3P8VUT5
names: Subcellular Location Annotation
messages: Golgi apparatus membrane
messages: Mitochondrion outer membrane

244447:LOC103392898
gene id: 244447:LOC103392898
uniprot id: A0A3P8VZ60
names: Function
names: Similarity
messages: Belongs to the parvalbumin family.
messages: In muscle, parvalbumin is thought to be involved in relaxation after contraction. It binds two calcium ions.

244447:LOC103380739
gene id: 244447:LOC103380739
uniprot id: A0A3P8WX19
names: Subcellular Location Annotation
messages: Cell membrane
messages: Endosome membrane
messages: Membrane
messages: Recycling endosome membrane
messages: cilium membrane

244447:LOC103395753
gene id: 244447:LOC103395753
uniprot id: A0A3P8X549
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

244447:lhfpl2
gene id: 244447:lhfpl2
uniprot id: A0A3P8W053
names: Subcellular Location Annotation
messages: Membrane

244447:LOC103391588
gene id: 244447:LOC103391588
uniprot id: A0A3P8UN79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Membrane

244447:LOC103397863
gene id: 244447:LOC103397863
uniprot id: A0A3P8X5G8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZNRF3 family.
messages: Cell membrane
messages: Membrane

244447:paip2
gene id: 244447:paip2
uniprot id: A0A3P8VXD6
names: Similarity
messages: Belongs to the PAIP2 family.

244447:LOC103384300
gene id: 244447:LOC103384300
uniprot id: A0A3P8WGE1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS37 family.
messages: Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. May be involved in cell growth and differentiation.
messages: Endosome membrane
messages: Late endosome membrane

244447:LOC103380246
gene id: 244447:LOC103380246
uniprot id: A0A3P8VEX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dwarfin/SMAD family.
messages: Cytoplasm
messages: Nucleus

244447:coch
gene id: 244447:coch
uniprot id: A0A3P8VYM4
names: Function
messages: Plays a role in the control of cell shape and motility in the trabecular meshwork.

244447:kdm3b
gene id: 244447:kdm3b
uniprot id: A0A3P8VVM1
uniprot id: A0A3P8VY99
names: Subcellular Location Annotation
messages: Nucleus

244447:npepl1
gene id: 244447:npepl1
uniprot id: A0A3P8USJ2
names: Similarity
messages: Belongs to the peptidase M17 family.

244447:nr3c1
gene id: 244447:nr3c1
uniprot id: A0A3P8WG92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR3 subfamily.
messages: Mitochondrion
messages: Nucleus
messages: centrosome
messages: spindle

244447:LOC103394629
gene id: 244447:LOC103394629
uniprot id: A0A3P8VNE0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 10 family.
messages: Golgi stack membrane

244447:LOC103379673
gene id: 244447:LOC103379673
uniprot id: A0A3P8UYD6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Forms a complex with PECAM1 and GNAQ. Interacts with PECAM1.
messages: Membrane
messages: Receptor for bradykinin. It is associated with G proteins that activate a phosphatidylinositol-calcium second messenger system.

244447:LOC103386470
gene id: 244447:LOC103386470
uniprot id: A0A3P8W2R9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

244447:LOC103383755
gene id: 244447:LOC103383755
uniprot id: A0A3P8VAK8
names: Similarity
messages: Belongs to the Luc7 family.

244447:LOC103390012
gene id: 244447:LOC103390012
uniprot id: A0A3P8W8I8
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

244447:LOC103386328
gene id: 244447:LOC103386328
uniprot id: A0A3P8VGQ7
uniprot id: A0A3P8VGT5
names: Cofactor
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfatase family.
messages: Binds 1 Ca(2+) ion per subunit.
messages: Cell surface
messages: Endoplasmic reticulum
messages: Golgi stack
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

244447:LOC103384737
gene id: 244447:LOC103384737
uniprot id: A0A3P8UN83
names: Similarity
messages: Belongs to the SKI family.

244447:nagpa
gene id: 244447:nagpa
uniprot id: A0A3P8UGI5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

244447:wdr24
gene id: 244447:wdr24
uniprot id: A0A3P8VWW9
names: Similarity
messages: Belongs to the WD repeat WDR24 family.

244447:mtfmt
gene id: 244447:mtfmt
uniprot id: A0A3P8VJJ6
names: Similarity
messages: Belongs to the Fmt family.

244447:trdmt1
gene id: 244447:trdmt1
uniprot id: A0A3P8VN27
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

244447:LOC103395349
gene id: 244447:LOC103395349
uniprot id: A0A3P8WAV3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.
messages: Membrane

244447:LOC103393995
gene id: 244447:LOC103393995
uniprot id: A0A3P8VNS5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mediator complex subunit 30 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Nucleus

244447:LOC103399945
gene id: 244447:LOC103399945
uniprot id: A0A3P8UDM5
names: Function
names: Similarity
messages: Belongs to the gamma-glutamylcyclotransferase family. ChaC subfamily.
messages: Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides.

244447:LOC103396602
gene id: 244447:LOC103396602
uniprot id: A0A3P8WZS0
names: Subcellular Location Annotation
messages: Membrane

244447:hs2st1
gene id: 244447:hs2st1
uniprot id: A0A3P8WJ92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 3 family.
messages: Membrane

244447:amylase
gene id: 244447:amylase
uniprot id: U3M7F5
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

244447:tyk2
gene id: 244447:tyk2
uniprot id: A0A3P8X4U7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. JAK subfamily.
messages: Endomembrane system

244447:LOC103396248
gene id: 244447:LOC103396248
uniprot id: A0A3P8WS34
names: Similarity
names: Subunit
messages: Belongs to the group II decarboxylase family.
messages: Homodimer.

244447:fbln7
gene id: 244447:fbln7
uniprot id: A0A3P8W0L3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

244447:atp1b3
gene id: 244447:atp1b3
uniprot id: A0A3P8WII5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the X(+)/potassium ATPases subunit beta family.
messages: Membrane
messages: This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane.

244447:lect2
gene id: 244447:lect2
uniprot id: A0A3P8UJT8
names: Similarity
messages: Belongs to the LECT2/MIM-1 family.

244447:LOC103381529
gene id: 244447:LOC103381529
uniprot id: A0A3P8VHG5
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

244447:tshr
gene id: 244447:tshr
uniprot id: A0A3P8WQ70
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Basolateral cell membrane
messages: Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily.
messages: Cell membrane
messages: Membrane
messages: Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a central role in controlling thyroid cell metabolism.

244447:brpf1
gene id: 244447:brpf1
uniprot id: A0A3P8X210
names: Subcellular Location Annotation
messages: Nucleus

244447:hpdl
gene id: 244447:hpdl
uniprot id: A0A3P8VNQ4
names: Cofactor
names: Similarity
messages: Belongs to the 4HPPD family.
messages: Binds 1 Fe cation per subunit.

244447:npl
gene id: 244447:npl
uniprot id: A0A3P8V8D7
names: Similarity
names: Subunit
messages: Belongs to the DapA family.
messages: Homotetramer.

244447:LOC103378475
gene id: 244447:LOC103378475
uniprot id: A0A3P8WSX7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat LIS1/nudF family.
messages: Can self-associate. Component of the cytosolic PAF-AH (I) heterotetrameric enzyme, which is composed of PAFAH1B1 (beta), PAFAH1B2 (alpha2) and PAFAH1B3 (alpha1) subunits. The catalytic activity of the enzyme resides in the alpha1 (PAFAH1B3) and alpha2 (PAFAH1B2) subunits, whereas the beta subunit (PAFAH1B1) has regulatory activity. Trimer formation is not essential for the catalytic activity (By similarity). Interacts with dynein, dynactin, nde1 and ndel1.
messages: Can self-associate. Interacts with dynein, dynactin, NDE1 and NDEL1.
messages: Dimerization mediated by the LisH domain may be required to activate dynein.
messages: Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. May be required for proliferation of neuronal precursors and neuronal migration.
messages: centrosome
messages: cytoskeleton

244447:chac1
gene id: 244447:chac1
uniprot id: A0A3P8UJ52
names: Function
names: Similarity
messages: Belongs to the gamma-glutamylcyclotransferase family. ChaC subfamily.
messages: Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides.

244447:phtf2
gene id: 244447:phtf2
uniprot id: A0A3P8VKH7
uniprot id: A0A3P8VNN0
uniprot id: A0A3P8VQT2
names: Subcellular Location Annotation
messages: Membrane

244447:smc6
gene id: 244447:smc6
uniprot id: A0A3P8WXY7
names: Subcellular Location Annotation
messages: Chromosome

244447:LOC103395389
gene id: 244447:LOC103395389
uniprot id: A0A3P8WMS2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: High affinity receptor for melatonin. The activity of this receptor is mediated by pertussis toxin sensitive G proteins that inhibits adenylate cyclase activity.
messages: Membrane

244447:smad2
gene id: 244447:smad2
uniprot id: A0A3P8WXQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dwarfin/SMAD family.
messages: Cytoplasm
messages: Nucleus

244447:evc
gene id: 244447:evc
uniprot id: A0A3P8VHK0
names: Subcellular Location Annotation
messages: Membrane
messages: cilium basal body
messages: cilium membrane

244447:ipo11
gene id: 244447:ipo11
uniprot id: A0A3P8WR00
names: Subcellular Location Annotation
messages: Cytoplasm

244447:sqstm1
gene id: 244447:sqstm1
uniprot id: A0A3P8V7K7
names: Subcellular Location Annotation
messages: autophagosome

244447:LOC103392402
gene id: 244447:LOC103392402
uniprot id: A0A3P8WKH3
names: Similarity
messages: Belongs to the glutaminase family.

244447:LOC103380366
gene id: 244447:LOC103380366
uniprot id: A0A3P8VME6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the biopterin-dependent aromatic amino acid hydroxylase family.
messages: axon
messages: perinuclear region

244447:LOC103389152
gene id: 244447:LOC103389152
uniprot id: A0A3P8WL14
names: Similarity
messages: Belongs to the IER family.

244447:LOC103392901
gene id: 244447:LOC103392901
uniprot id: A0A3P8W1X4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
messages: Membrane
messages: Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs), including GRIA1 and GRIA4. Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization.

244447:mrpl9
gene id: 244447:mrpl9
uniprot id: A0A3P8VCA6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.

244447:kdm5a
gene id: 244447:kdm5a
uniprot id: A0A3P8W1L2
names: Similarity
messages: Belongs to the JARID1 histone demethylase family.

244447:fam168b
gene id: 244447:fam168b
uniprot id: A0A3P8W0K1
names: Similarity
messages: Belongs to the FAM168 family.

244447:ubn2
gene id: 244447:ubn2
uniprot id: A0A3P8VE64
names: Similarity
messages: Belongs to the ubinuclein family.

244447:LOC103386542
gene id: 244447:LOC103386542
uniprot id: A0A3P8WFB8
names: Similarity
messages: Belongs to the beta-catenin family.

244447:rassf1
gene id: 244447:rassf1
uniprot id: A0A3P8X4L6
names: Subcellular Location Annotation
messages: cytoskeleton

244447:ruvbl2
gene id: 244447:ruvbl2
uniprot id: A0A3P8VTT2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RuvB family.
messages: Dynein axonemal particle
messages: Nucleus
messages: Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding.

244447:csnk1a1
gene id: 244447:csnk1a1
uniprot id: A0A3P8X377
names: Similarity
messages: Belongs to the protein kinase superfamily.

244447:LOC103396028
gene id: 244447:LOC103396028
uniprot id: A0A3P8WJY3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glypican family.
messages: Cell membrane
messages: Cell surface proteoglycan that bears heparan sulfate.
messages: extracellular space

244447:LOC103378786
gene id: 244447:LOC103378786
uniprot id: A0A3P8UPN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 6 family.
messages: Membrane

244447:snx11
gene id: 244447:snx11
uniprot id: A0A3P8W690
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Membrane

244447:LOC103385452
gene id: 244447:LOC103385452
uniprot id: A0A3P8X5L5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 7 family.
messages: Golgi apparatus membrane
messages: Membrane
messages: Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids.

244447:malt1
gene id: 244447:malt1
uniprot id: A0A3P8WPG4
uniprot id: A0A3P8WRB9
uniprot id: A0A3P8WRF2
uniprot id: A0A3P8WX79
names: Subcellular Location Annotation
messages: Membrane

244447:LOC103390712
gene id: 244447:LOC103390712
uniprot id: A0A3P8UXG8
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family.

244447:LOC103381741
gene id: 244447:LOC103381741
uniprot id: A0A3P8W4U2
names: Similarity
messages: Belongs to the EPS8 family.

244447:p4ha1
gene id: 244447:p4ha1
uniprot id: A0A3P8V3H7
uniprot id: A0A3P8V3I6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P4HA family.
messages: Catalyzes the post-translational formation of 4-hydroxyproline in -Xaa-Pro-Gly- sequences in collagens and other proteins.
messages: Endoplasmic reticulum lumen

244447:plekha8
gene id: 244447:plekha8
uniprot id: A0A3P8V0D9
names: Subcellular Location Annotation
messages: Membrane
messages: trans-Golgi network membrane

244447:pea15
gene id: 244447:pea15
uniprot id: A0A3P8WKC7
names: Subcellular Location Annotation
messages: Cytoplasm

244447:snrpd1
gene id: 244447:snrpd1
uniprot id: A0A3P8WUL8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP core protein family.
messages: Nucleus
messages: Plays a role in pre-mRNA splicing as a core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome.

244447:LOC103393253
gene id: 244447:LOC103393253
uniprot id: A0A3P8W4E8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: tight junction

244447:ttc39a
gene id: 244447:ttc39a
uniprot id: A0A3P8WXQ4
names: Similarity
messages: Belongs to the TTC39 family.

244447:LOC103391128
gene id: 244447:LOC103391128
uniprot id: A0A3P8W1G3
uniprot id: A0A3P8W4B7
names: Similarity
messages: Belongs to the phospholipase D family.

244447:rexo2
gene id: 244447:rexo2
uniprot id: A0A3P8VAM1
names: Similarity
messages: Belongs to the oligoribonuclease family.

244447:asic1
gene id: 244447:asic1
uniprot id: A0A3P8WQ91
uniprot id: A0A3P8WQ96
uniprot id: A0A3P8WW59
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

244447:LOC103391567
gene id: 244447:LOC103391567
uniprot id: A0A3P8UQZ1
names: Similarity
messages: Belongs to the tumor necrosis factor family.

244447:LOC103380531
gene id: 244447:LOC103380531
uniprot id: A0A3P8W4M0
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

244447:LOC103379306
gene id: 244447:LOC103379306
uniprot id: A0A3P8VU16
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adaptor complexes small subunit family.
messages: Cytoplasmic vesicle membrane
messages: Membrane
messages: Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals.

244447:LOC103395392
gene id: 244447:LOC103395392
uniprot id: A0A3P8WHG3
names: Subcellular Location Annotation
messages: Membrane

244447:LOC103379430
gene id: 244447:LOC103379430
uniprot id: A0A3P8W6W8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CUT homeobox family.
messages: Nucleus

244447:LOC103391731
gene id: 244447:LOC103391731
uniprot id: A0A3P8UWH5
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

244447:mrpl33
gene id: 244447:mrpl33
uniprot id: A0A3P8UVT6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

244447:LOC103387407
gene id: 244447:LOC103387407
uniprot id: A0A3P8VJ39
names: Function
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
messages: Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues within the same substrate, with a preference for phosphotyrosine as a substrate (By similarity). Involved in the modulation of AMPK and MAPK1/2 signaling pathways.
messages: Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate.

244447:robo2
gene id: 244447:robo2
uniprot id: A0A3P8VCN4
names: Subcellular Location Annotation
messages: Membrane

244447:top3a
gene id: 244447:top3a
uniprot id: A0A3P8V9K1
names: Function
names: Similarity
messages: Belongs to the type IA topoisomerase family.
messages: Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand.

244447:etfb
gene id: 244447:etfb
uniprot id: A0A3P8UGX9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ETF beta-subunit/FixA family.
messages: Heterodimer of an alpha and a beta subunit.
messages: Mitochondrion matrix
messages: The electron transfer flavoprotein serves as a specific electron acceptor for several dehydrogenases, including five acyl-CoA dehydrogenases, glutaryl-CoA and sarcosine dehydrogenase. It transfers the electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

244447:lpin2
gene id: 244447:lpin2
uniprot id: A0A3P8UB48
names: Similarity
messages: Belongs to the lipin family.

244447:smoc1
gene id: 244447:smoc1
uniprot id: A0A3P8VKC2
uniprot id: A0A3P8VQN5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

244447:LOC103399917
gene id: 244447:LOC103399917
uniprot id: A0A3P8UPD4
names: Subcellular Location Annotation
messages: extracellular space

244447:neurod2
gene id: 244447:neurod2
uniprot id: A0A3P8WEG7
names: Subcellular Location Annotation
messages: Nucleus

244447:LOC103396218
gene id: 244447:LOC103396218
uniprot id: A0A3P8VN38
names: Similarity
names: Subcellular Location Annotation
messages: A band
messages: Belongs to the KLHL40 family.
messages: I band

244447:ntrk1
gene id: 244447:ntrk1
uniprot id: A0A3P8W789
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. Insulin receptor subfamily.
messages: Cell membrane
messages: Membrane

244447:pla1a
gene id: 244447:pla1a
uniprot id: A0A3P8VIZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AB hydrolase superfamily. Lipase family.
messages: Secreted

244447:LOC103385350
gene id: 244447:LOC103385350
uniprot id: A0A3P8WQN9
names: Similarity
messages: Belongs to the TAFA family.

244447:LOC103393386
gene id: 244447:LOC103393386
uniprot id: A0A3P8W5M0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paired homeobox family. Bicoid subfamily.
messages: Nucleus
messages: Plays a critical role in eye formation by regulating the initial specification of retinal cells and/or their subsequent proliferation.

244447:osbpl11
gene id: 244447:osbpl11
uniprot id: A0A3P8UX57
names: Similarity
messages: Belongs to the OSBP family.

244447:LOC103389703
gene id: 244447:LOC103389703
uniprot id: A0A3P8W099
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

244447:LOC103397787
gene id: 244447:LOC103397787
uniprot id: A0A3P8X0K6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

244447:LOC103394152
gene id: 244447:LOC103394152
uniprot id: A0A3P8W7X2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the teashirt C2H2-type zinc-finger protein family.
messages: Nucleus

244447:inha
gene id: 244447:inha
uniprot id: A0A3P8V308
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TGF-beta family.
messages: Dimeric, linked by one or more disulfide bonds. Inhibin A is a dimer of alpha and beta-A. Inhibin B is a dimer of alpha and beta-B.
messages: Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition.
messages: Secreted

244447:LOC103392834
gene id: 244447:LOC103392834
uniprot id: A0A3P8VZ75
names: Similarity
messages: Belongs to the cytidylyltransferase family.

244447:tiprl
gene id: 244447:tiprl
uniprot id: A0A3P8V7T0
names: Similarity
messages: Belongs to the TIP41 family.

244447:LOC103378407
gene id: 244447:LOC103378407
uniprot id: A0A3P8WGB3
names: Subcellular Location Annotation
messages: Membrane

244447:dhh
gene id: 244447:dhh
uniprot id: A0A3P8VEZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the hedgehog family.
messages: Cell membrane
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Membrane
messages: Multimer.
messages: The C-terminal part of the hedgehog protein precursor displays an autoproteolysis activity that results in the cleavage of the full-length protein into two parts (N-product and C-product). In addition, the C-terminal part displays a cholesterol transferase activity that results by the covalent attachment of a cholesterol moiety to the C-terminal of the newly generated N-product.
messages: The dually lipidated hedgehog protein N-product is a morphogen which is essential for a variety of patterning events during development.

244447:LOC103398246
gene id: 244447:LOC103398246
uniprot id: A0A3P8WD84
names: Function
names: Subcellular Location Annotation
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Nucleus

244447:smc4
gene id: 244447:smc4
uniprot id: A0A3P8WN45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMC family. SMC4 subfamily.
messages: Chromosome
messages: Nucleus

244447:cenph
gene id: 244447:cenph
uniprot id: A0A3P8WKG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CENP-H/MCM16 family.
messages: Nucleus
messages: kinetochore

244447:LOC103392792
gene id: 244447:LOC103392792
uniprot id: A0A3P8VY68
names: Similarity
messages: Belongs to the SNF7 family.

244447:iapp
gene id: 244447:iapp
uniprot id: A0A3P8WB66
names: Function
names: Similarity
messages: Belongs to the calcitonin family.
messages: Causes a rapid but short-lived drop in the level of calcium and phosphate in blood by promoting the incorporation of those ions in the bones.

244447:adprhl1
gene id: 244447:adprhl1
uniprot id: A0A3P8VC88
names: Similarity
messages: Belongs to the ADP-ribosylglycohydrolase family.

244447:ap3b1
gene id: 244447:ap3b1
uniprot id: A0A3P8W0E4
uniprot id: A0A3P8W5T7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adaptor complexes large subunit family.
messages: Subunit of non-clathrin- and clathrin-associated adaptor protein complex 3 (AP-3) that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. AP-3 appears to be involved in the sorting of a subset of transmembrane proteins targeted to lysosomes and lysosome-related organelles. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals.
messages: clathrin-coated vesicle membrane

244447:LOC103392327
gene id: 244447:LOC103392327
uniprot id: A0A3P8W214
names: Subcellular Location Annotation
messages: Membrane

244447:thop1
gene id: 244447:thop1
uniprot id: A0A3P8X0M9
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

244447:tsnax
gene id: 244447:tsnax
uniprot id: A0A3P8W7P7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the translin family.
messages: Nucleus

244447:rnf2
gene id: 244447:rnf2
uniprot id: A0A3P8X536
names: Subcellular Location Annotation
messages: Chromosome
messages: Cytoplasm

244447:mrpl46
gene id: 244447:mrpl46
uniprot id: A0A3P8VQF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL46 family.
messages: Mitochondrion

244447:prpf31
gene id: 244447:prpf31
uniprot id: A0A3P8WY08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRP31 family.
messages: Cajal body

244447:nr0b1
gene id: 244447:nr0b1
uniprot id: E5D064
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR0 subfamily.
messages: Cytoplasm
messages: Nucleus

244447:LOC103394542
gene id: 244447:LOC103394542
uniprot id: A0A3P8V777
names: Similarity
messages: Belongs to the proteasome subunit S5A family.

244447:ndufb11
gene id: 244447:ndufb11
uniprot id: A0A3P8UYX0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFB11 subunit family.
messages: Membrane

244447:LOC103396679
gene id: 244447:LOC103396679
uniprot id: A0A3P8X3I6
names: Similarity
messages: Belongs to the peptidase C1 family.

244447:LOC103399929
gene id: 244447:LOC103399929
uniprot id: A0A3P8UR84
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

244447:LOC103382815
gene id: 244447:LOC103382815
uniprot id: A0A3P8VKC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the round spermatid basic protein 1 family.
messages: Nucleus

244447:LOC103393589
gene id: 244447:LOC103393589
uniprot id: A0A3P8W703
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.
messages: Membrane

244447:ube3d
gene id: 244447:ube3d
uniprot id: A0A3P8VHQ7
names: Function
messages: E3 ubiquitin-protein ligase which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, and transfers it to substrates, generally promoting their degradation by the proteasome.

244447:dusp5
gene id: 244447:dusp5
uniprot id: A0A3P8W2L1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
messages: Nucleus

244447:LOC103391391
gene id: 244447:LOC103391391
uniprot id: A0A3P8X0T4
names: Subcellular Location Annotation
messages: Nucleus

244447:ndufs6
gene id: 244447:ndufs6
uniprot id: A0A3P8VVC4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFS6 subunit family.
messages: Mitochondrion inner membrane

244447:LOC103385141
gene id: 244447:LOC103385141
uniprot id: A0A3P8VBY1
names: Similarity
messages: Belongs to the cyclin family. Cyclin AB subfamily.

244447:mocs3
gene id: 244447:mocs3
uniprot id: A0A3P8UHD4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: In the N-terminal section; belongs to the HesA/MoeB/ThiF family. UBA4 subfamily.
messages: Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Also essential during biosynthesis of the molybdenum cofactor. Acts by mediating the C-terminal thiocarboxylation of sulfur carriers URM1 and MOCS2A. Its N-terminus first activates URM1 and MOCS2A as acyl-adenylates (-COAMP), then the persulfide sulfur on the catalytic cysteine is transferred to URM1 and MOCS2A to form thiocarboxylation (-COSH) of their C-terminus. The reaction probably involves hydrogen sulfide that is generated from the persulfide intermediate and that acts as nucleophile towards URM1 and MOCS2A. Subsequently, a transient disulfide bond is formed. Does not use thiosulfate as sulfur donor; NFS1 probably acting as a sulfur donor for thiocarboxylation reactions.

244447:pcid2
gene id: 244447:pcid2
uniprot id: A0A3P8VKT0
names: Similarity
messages: Belongs to the CSN12 family.

244447:calhm1
gene id: 244447:calhm1
uniprot id: A0A3P8VMY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CALHM family.
messages: Membrane

244447:snx14
gene id: 244447:snx14
uniprot id: A0A3P8UMX5
uniprot id: A0A3P8USR4
names: Similarity
messages: Belongs to the sorting nexin family.

244447:LOC103387754
gene id: 244447:LOC103387754
uniprot id: H6T596
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the somatotropin/prolactin family.
messages: Secreted

244447:LOC103380335
gene id: 244447:LOC103380335
uniprot id: A0A3P8VIX4
names: Caution
names: Similarity
messages: Belongs to the plexin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

244447:LOC103388840
gene id: 244447:LOC103388840
uniprot id: A0A3P8W0C7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SH3BP5 family.
messages: Cytoplasm
messages: Functions as guanine nucleotide exchange factor (GEF) for RAB11A.
messages: Interacts with GDP-bound and nucleotide-free forms of RAB11A.
messages: The N-terminal half of the protein mediates interaction with RAB11A and functions as guanine nucleotide exchange factor. Four long alpha-helices (interrupted by a central kink) assemble into coiled coils, giving rise to a 'V' shape.

244447:dctd
gene id: 244447:dctd
uniprot id: A0A3P8VRB5
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

244447:LOC103395590
gene id: 244447:LOC103395590
uniprot id: A0A3P8WZ15
uniprot id: A0A3P8X417
names: Subcellular Location Annotation
messages: Membrane

244447:LOC103385414
gene id: 244447:LOC103385414
uniprot id: A0A3P8WML1
names: Similarity
messages: Belongs to the SPATA6 family.

244447:egr3
gene id: 244447:egr3
uniprot id: A0A3P8W5V6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EGR C2H2-type zinc-finger protein family.
messages: Nucleus

244447:efna4
gene id: 244447:efna4
uniprot id: A0A3P8UJ77
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ephrin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

244447:galnt13
gene id: 244447:galnt13
uniprot id: A0A3P8VTB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

244447:LOC103382004
gene id: 244447:LOC103382004
uniprot id: A0A3P8WXU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HARBI1 family.
messages: Nucleus

244447:pten
gene id: 244447:pten
uniprot id: A0A3P8ULU5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine-phosphorylated proteins. Also acts as a lipid phosphatase, removing the phosphate in the D3 position of the inositol ring from phosphatidylinositol 3,4,5-trisphosphate, phosphatidylinositol 3,4-diphosphate, phosphatidylinositol 3-phosphate and inositol 1,3,4,5-tetrakisphosphate with order of substrate preference in vitro PtdIns(3,4,5)P3 > PtdIns(3,4)P2 > PtdIns3P > Ins(1,3,4,5)P4.
messages: Belongs to the PTEN phosphatase protein family.
messages: Cytoplasm
messages: Nucleus
messages: PML body
messages: Postsynaptic density
messages: dendritic spine

244447:LOC103384897
gene id: 244447:LOC103384897
uniprot id: A0A3P8V1C3
uniprot id: A0A3P8V1D4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class 2 subfamily.
messages: Cytoplasm

244447:rps3a
gene id: 244447:rps3a
uniprot id: A0A3P8UMH8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS1 family.
messages: Component of the small ribosomal subunit. Mature ribosomes consist of a small (40S) and a large (60S) subunit. The 40S subunit contains about 33 different proteins and 1 molecule of RNA (18S). The 60S subunit contains about 49 different proteins and 3 molecules of RNA (28S, 5.8S and 5S).
messages: Cytoplasm

244447:LOC103391040
gene id: 244447:LOC103391040
uniprot id: A0A3P8VWG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

244447:clu
gene id: 244447:clu
uniprot id: A0A3P8UY11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the clusterin family.
messages: Endoplasmic reticulum
messages: Membrane
messages: Mitochondrion membrane
messages: Nucleus
messages: Secreted
messages: chromaffin granule
messages: cytosol

244447:LOC103388392
gene id: 244447:LOC103388392
uniprot id: A0A3P8UY09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATXN1 family.
messages: Nucleus

244447:cplx4
gene id: 244447:cplx4
uniprot id: A0A3P8WW33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complexin/synaphin family.
messages: Synapse

244447:ddo
gene id: 244447:ddo
uniprot id: A0A3P8UTU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DAMOX/DASOX family.
messages: Peroxisome

244447:LOC103389839
gene id: 244447:LOC103389839
uniprot id: A0A3P8VK89
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

244447:LOC103381624
gene id: 244447:LOC103381624
uniprot id: A0A3P8VKY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family.
messages: Membrane

244447:LOC103381978
gene id: 244447:LOC103381978
uniprot id: A0A3P8WR47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

244447:mrpl47
gene id: 244447:mrpl47
uniprot id: A0A3P8W6L9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal ribosomal protein uL29 family.
messages: Mitochondrion

244447:kif22
gene id: 244447:kif22
uniprot id: A0A3P8WLL3
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

244447:xpo6
gene id: 244447:xpo6
uniprot id: A0A3P8W6W9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exportin family.
messages: Cytoplasm
messages: Nucleus

244447:LOC103379796
gene id: 244447:LOC103379796
uniprot id: A0A3P8UGW2
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 4 family.

244447:LOC103392486
gene id: 244447:LOC103392486
uniprot id: A0A3P8X136
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAR3 family.
messages: Cell junction
messages: Endomembrane system

244447:LOC103383594
gene id: 244447:LOC103383594
uniprot id: A0A1L6KTK2
names: Subcellular Location Annotation
names: Subunit
messages: Cell membrane
messages: Interacts with NCDN.
messages: Membrane

244447:LOC103378934
gene id: 244447:LOC103378934
uniprot id: A0A3P8V414
names: Similarity
messages: Belongs to the TCF/LEF family.

244447:acads
gene id: 244447:acads
uniprot id: A0A3P8VUS8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

244447:LOC103386847
gene id: 244447:LOC103386847
uniprot id: A0A3P8X0P9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c family.
messages: Membrane
messages: Mitochondrion inner membrane

244447:LOC103391867
gene id: 244447:LOC103391867
uniprot id: A0A3P8V019
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus

244447:gpt
gene id: 244447:gpt
uniprot id: A0A3P8VRA2
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. Alanine aminotransferase subfamily.
messages: Homodimer.

244447:LOC103394672
gene id: 244447:LOC103394672
uniprot id: A0A3P8VHL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MTURN family.
messages: Cytoplasm

244447:icmt
gene id: 244447:icmt
uniprot id: A0A3P8UX79
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class VI-like SAM-binding methyltransferase superfamily. Isoprenylcysteine carboxyl methyltransferase family.
messages: Catalyzes the post-translational methylation of isoprenylated C-terminal cysteine residues.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

244447:LOC103378756
gene id: 244447:LOC103378756
uniprot id: A0A3P8UM93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM CPSF6/7 family.
messages: Nucleus

244447:LOC103387713
gene id: 244447:LOC103387713
uniprot id: A0A3P8WHZ7
names: Subcellular Location Annotation
messages: Nucleus

244447:mccc2
gene id: 244447:mccc2
uniprot id: A0A3P8VAY1
names: Similarity
messages: Belongs to the AccD/PCCB family.

244447:LOC103385568
gene id: 244447:LOC103385568
uniprot id: A0A3P8X1M3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NEMP family.
messages: Nucleus inner membrane

244447:arl8b
gene id: 244447:arl8b
uniprot id: A0A3P8X6F5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane

244447:b3gnt7
gene id: 244447:b3gnt7
uniprot id: A0A3P8WBB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

244447:p4ha3
gene id: 244447:p4ha3
uniprot id: A0A3P8VQI5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P4HA family.
messages: Catalyzes the post-translational formation of 4-hydroxyproline in -Xaa-Pro-Gly- sequences in collagens and other proteins.
messages: Endoplasmic reticulum lumen

244447:med28
gene id: 244447:med28
uniprot id: A0A3P8VZ06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mediator complex subunit 28 family.
messages: Nucleus

244447:mrps24
gene id: 244447:mrps24
uniprot id: A0A3P8VDM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Mitochondrion

244447:LOC103380601
gene id: 244447:LOC103380601
uniprot id: A0A3P8WBG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

244447:ace2
gene id: 244447:ace2
uniprot id: A0A3P8UEB1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the peptidase M2 family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Membrane
messages: Secreted
messages: cilium

244447:lin7c
gene id: 244447:lin7c
uniprot id: A0A3P8UHX1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lin-7 family.
messages: Cell junction
messages: Cell membrane
messages: Membrane
messages: Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells.

244447:LOC103377690
gene id: 244447:LOC103377690
uniprot id: A0A3P8US33
names: Subcellular Location Annotation
messages: Membrane

244447:rars2
gene id: 244447:rars2
uniprot id: A0A3P8UWW3
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

244447:tp53
gene id: 244447:tp53
uniprot id: A0A3P8UNQ6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression.
messages: Belongs to the p53 family.
messages: Binds 1 zinc ion per subunit.
messages: Binds DNA as a homotetramer.
messages: Cytoplasm
messages: Nucleus

244447:LOC103390297
gene id: 244447:LOC103390297
uniprot id: A0A3P8WXR5
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

244447:samhd1
gene id: 244447:samhd1
uniprot id: A0A3P8X5N2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SAMHD1 family.
messages: Chromosome

244447:LOC103389777
gene id: 244447:LOC103389777
uniprot id: A0A3P8W8J3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the milton family.
messages: Early endosome
messages: Mitochondrion

244447:map2k4
gene id: 244447:map2k4
uniprot id: A0A3P8UQZ3
names: Similarity
messages: Belongs to the protein kinase superfamily.

244447:LOC103387327
gene id: 244447:LOC103387327
uniprot id: A0A3P8V7J9
names: Subcellular Location Annotation
messages: Membrane

244447:tmem218
gene id: 244447:tmem218
uniprot id: A0A3P8WK55
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM218 family.
messages: May be involved in ciliary biogenesis or function.
messages: Membrane
messages: cilium

244447:tspan33
gene id: 244447:tspan33
uniprot id: A0A3P8VIZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

244447:LOC103394838
gene id: 244447:LOC103394838
uniprot id: A0A3P8W0U8
names: Similarity
messages: Belongs to the glycosyl hydrolase 35 family.

244447:tspan3
gene id: 244447:tspan3
uniprot id: A0A3P8VE09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

244447:tprkb
gene id: 244447:tprkb
uniprot id: A0A3P8VYL1
names: Similarity
messages: Belongs to the CGI121/TPRKB family.

244447:mfsd4a
gene id: 244447:mfsd4a
uniprot id: A0A3P8WSG1
names: Subcellular Location Annotation
messages: Membrane

244447:chmp3
gene id: 244447:chmp3
uniprot id: A0A3P8UMS8
names: Similarity
messages: Belongs to the SNF7 family.

244447:slc2a5
gene id: 244447:slc2a5
uniprot id: A0A3P8VCZ9
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

244447:LOC103395373
gene id: 244447:LOC103395373
uniprot id: A0A3P8WE24
names: Similarity
messages: Belongs to the CRK family.

244447:LOC103384383
gene id: 244447:LOC103384383
uniprot id: A0A3P8WHA5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetyltransferase ATAT1 family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically acetylates 'Lys-40' in alpha-tubulin on the lumenal side of microtubules. Promotes microtubule destabilization and accelerates microtubule dynamics; this activity may be independent of acetylation activity. Acetylates alpha-tubulin with a slow enzymatic rate, due to a catalytic site that is not optimized for acetyl transfer. Enters the microtubule through each end and diffuses quickly throughout the lumen of microtubules. Acetylates only long/old microtubules because of its slow acetylation rate since it does not have time to act on dynamically unstable microtubules before the enzyme is released. May be involved in neuron development.
messages: axon
messages: clathrin-coated pit
messages: cytoskeleton
messages: focal adhesion
messages: spindle

244447:b3glct
gene id: 244447:b3glct
uniprot id: A0A3P8VZI5
names: Subcellular Location Annotation
messages: Membrane

244447:sost
gene id: 244447:sost
uniprot id: A0A3P8W8G5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the sclerostin family.
messages: Interacts with LRP4 (via the extracellular domain); the interaction facilitates the inhibition of Wnt signaling. Interacts with LRP5 (via the first two YWTD-EGF repeat domains); the interaction inhibits Wnt-mediated signaling. Interacts with LRP6.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Negative regulator of bone growth that acts through inhibition of Wnt signaling and bone formation.

244447:LOC103388433
gene id: 244447:LOC103388433
uniprot id: A0A3P8UVX7
names: Similarity
messages: Belongs to the OSBP family.

244447:LOC103387527
gene id: 244447:LOC103387527
uniprot id: A0A3P8VNN9
names: Subcellular Location Annotation
messages: Nucleus

244447:LOC103394711
gene id: 244447:LOC103394711
uniprot id: A0A3P8VSP4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatase and actin regulator family.
messages: Binds PPP1CA and actin.
messages: Cytoplasm
messages: lamellipodium

244447:tbx3
gene id: 244447:tbx3
uniprot id: A0A3P8WJQ3
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

244447:LOC103381031
gene id: 244447:LOC103381031
uniprot id: A0A3P8UT31
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

244447:snf8
gene id: 244447:snf8
uniprot id: A0A3P8W8H9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SNF8 family.
messages: Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs.
messages: Component of the endosomal sorting complex required for transport II (ESCRT-II).

244447:nek9
gene id: 244447:nek9
uniprot id: A0A3P8UG24
names: Similarity
messages: Belongs to the protein kinase superfamily. NEK Ser/Thr protein kinase family. NIMA subfamily.

244447:mmachc
gene id: 244447:mmachc
uniprot id: A0A3P8VHF8
names: Similarity
messages: Belongs to the MMACHC family.

244447:LOC103384901
gene id: 244447:LOC103384901
uniprot id: A0A3P8UXA2
names: Similarity
messages: Belongs to the TAFA family.

244447:ctrl
gene id: 244447:ctrl
uniprot id: A0A3P8V8F2
names: Subcellular Location Annotation
messages: extracellular space

244447:LOC103388422
gene id: 244447:LOC103388422
uniprot id: A0A3P8V030
names: Similarity
messages: Belongs to the HIBADH-related family. 3-hydroxyisobutyrate dehydrogenase subfamily.

244447:LOC103380401
gene id: 244447:LOC103380401
uniprot id: A0A3P8VMJ8
names: Similarity
messages: Belongs to the DNA photolyase class-1 family.

244447:mindy2
gene id: 244447:mindy2
uniprot id: A0A3P8UJ49
names: Function
names: Similarity
messages: Belongs to the MINDY deubiquitinase family. FAM63 subfamily.
messages: Hydrolase that can specifically remove 'Lys-48'-linked conjugated ubiquitin from proteins. Has exodeubiquitinase activity and has a preference for long polyubiquitin chains. May play a regulatory role at the level of protein turnover.

244447:cdk2
gene id: 244447:cdk2
uniprot id: A0A3P8UTF2
names: Similarity
messages: Belongs to the protein kinase superfamily.

244447:sdr42e1
gene id: 244447:sdr42e1
uniprot id: A0A3P8VWS3
names: Similarity
messages: Belongs to the 3-beta-HSD family.

244447:naa40
gene id: 244447:naa40
uniprot id: A0A3P8WFH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetyltransferase family. NAA40 subfamily.
messages: Cytoplasm
messages: Nucleus

244447:pfdn5
gene id: 244447:pfdn5
uniprot id: A0A3P8UW93
names: Similarity
messages: Belongs to the prefoldin subunit alpha family.

244447:LOC103388004
gene id: 244447:LOC103388004
uniprot id: A0A3P8WTZ7
names: Similarity
messages: Belongs to the ATG8 family.

244447:cd28
gene id: 244447:cd28
uniprot id: H9LUM9
names: Subcellular Location Annotation
messages: Membrane

244447:terf2ip
gene id: 244447:terf2ip
uniprot id: A0A3P8X643
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts both as a regulator of telomere function and as a transcription regulator. Involved in the regulation of telomere length and protection as a component of the shelterin complex (telosome). Does not bind DNA directly: recruited to telomeric double-stranded 5'-TTAGGG-3' repeats via its interaction with terf2. Independently of its function in telomeres, also acts as a transcription regulator: recruited to extratelomeric 5'-TTAGGG-3' sites via its association with terf2 or other factors, and regulates gene expression.
messages: Belongs to the RAP1 family.
messages: Homodimer.
messages: Nucleus
messages: telomere

244447:LOC103389540
gene id: 244447:LOC103389540
uniprot id: A0A3P8V736
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

244447:mrs2
gene id: 244447:mrs2
uniprot id: A0A3P8V630
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mitochondrion inner membrane

244447:slc6a9
gene id: 244447:slc6a9
uniprot id: A0A3P8X1L5
uniprot id: A0A3P8X215
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A9 subfamily.
messages: Cell membrane
messages: Membrane

244447:grpel1
gene id: 244447:grpel1
uniprot id: A0A3P8WRQ1
names: Similarity
messages: Belongs to the GrpE family.

244447:jak2
gene id: 244447:jak2
uniprot id: A0A3P8WKX7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. JAK subfamily.
messages: Endomembrane system

244447:slc30a1
gene id: 244447:slc30a1
uniprot id: A0A3P8X0Z5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
messages: Membrane

244447:mfrp
gene id: 244447:mfrp
uniprot id: A0A3P8W8L3
names: Caution
names: Subcellular Location Annotation
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

244447:hoxd3
gene id: 244447:hoxd3
uniprot id: A0A3P8V3T2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

244447:gpd1l
gene id: 244447:gpd1l
uniprot id: A0A3P8VSF1
names: Similarity
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.

244447:zfpl1
gene id: 244447:zfpl1
uniprot id: A0A3P8WEW3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZFPL1 family.
messages: Membrane
messages: Required for cis-Golgi integrity and efficient ER to Golgi transport.
messages: The B box-type and RING-type zinc fingers although degenerate play a central role in function of the protein.
messages: cis-Golgi network membrane

244447:msh2
gene id: 244447:msh2
uniprot id: A0A3P8VP88
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA mismatch repair MutS family.
messages: Component of the post-replicative DNA mismatch repair system (MMR).
messages: Nucleus

244447:sec31a
gene id: 244447:sec31a
uniprot id: A0A3P8VRY6
uniprot id: A0A3P8VUY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat SEC31 family.
messages: Endoplasmic reticulum membrane

244447:rpl8
gene id: 244447:rpl8
uniprot id: A0A3P8V0P5
names: Similarity
messages: Belongs to the universal ribosomal protein uL2 family.

244447:LOC103390762
gene id: 244447:LOC103390762
uniprot id: A0A3P8UZK3
uniprot id: A0A3P8V105
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inositol 1,4,5-trisphosphate 5-phosphatase family.
messages: Membrane
messages: Nucleus speckle
messages: filopodium
messages: lamellipodium

244447:LOC103389949
gene id: 244447:LOC103389949
uniprot id: A0A3P8VVI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELL/occludin family.
messages: Cell membrane
messages: Membrane
messages: tight junction

244447:gata3
gene id: 244447:gata3
uniprot id: A0A3P8WVD6
names: Subcellular Location Annotation
messages: Nucleus

244447:LOC103387402
gene id: 244447:LOC103387402
uniprot id: A0A3P8VIC7
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular space

244447:cwf19l1
gene id: 244447:cwf19l1
uniprot id: A0A3P8UWD1
names: Similarity
messages: Belongs to the CWF19 family.

244447:tmem230
gene id: 244447:tmem230
uniprot id: A0A3P8UHB4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM134/TMEM230 family.
messages: Early endosome
messages: Endosome
messages: Involved in trafficking and recycling of synaptic vesicles.
messages: Late endosome
messages: Membrane
messages: Recycling endosome
messages: Vesicle
messages: autophagosome
messages: synaptic vesicle
messages: trans-Golgi network

244447:LOC103390455
gene id: 244447:LOC103390455
uniprot id: A0A3P8UGE2
uniprot id: A0A3P8UPS5
names: Subcellular Location Annotation
messages: Cell membrane

244447:LOC103399010
gene id: 244447:LOC103399010
uniprot id: A0A3P8UIF6
uniprot id: A0A3P8ULV7
uniprot id: A0A3P8UMY8
uniprot id: A0A3P8UN04
names: Similarity
messages: Belongs to the PI3K p85 subunit family.

244447:LOC103387539
gene id: 244447:LOC103387539
uniprot id: A0A3P8VV96
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NSE4 family.
messages: Component of the SMC5-SMC6 complex, that promotes sister chromatid alignment after DNA damage and facilitates double-stranded DNA breaks (DSBs) repair via homologous recombination between sister chromatids.
messages: Component of the SMC5-SMC6 complex.
messages: Nucleus
messages: telomere

244447:chmp6
gene id: 244447:chmp6
uniprot id: A0A3P8UN62
names: Similarity
messages: Belongs to the SNF7 family.

244447:LOC103380984
gene id: 244447:LOC103380984
uniprot id: A0A3P8UE51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

244447:cnih4
gene id: 244447:cnih4
uniprot id: A0A3P8VQ05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cornichon family.
messages: Membrane

244447:rgn
gene id: 244447:rgn
uniprot id: A0A3P8WFI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMP-30/CGR1 family.
messages: Cytoplasm

244447:fam155a
gene id: 244447:fam155a
uniprot id: A0A3P8VTC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NALF family.
messages: Membrane

244447:mmp9
gene id: 244447:mmp9
uniprot id: A0A3P8UL39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M10A family.
messages: extracellular matrix

244447:LOC103382737
gene id: 244447:LOC103382737
uniprot id: A0A3P8VHE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TUB family.
messages: Secreted

244447:LOC103378505
gene id: 244447:LOC103378505
uniprot id: A0A3P8WUQ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BCAP29/BCAP31 family.
messages: Endoplasmic reticulum membrane
messages: May play a role in anterograde transport of membrane proteins from the endoplasmic reticulum to the Golgi.
messages: Membrane

244447:LOC103384622
gene id: 244447:LOC103384622
uniprot id: A0A3P8UMJ1
uniprot id: A0A3P8UMK4
names: Similarity
messages: Belongs to the DIP2 family.

244447:edc4
gene id: 244447:edc4
uniprot id: A0A3P8W8Q5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat EDC4 family.
messages: P-body

244447:bmp3
gene id: 244447:bmp3
uniprot id: A0A3P8WFF9
names: Similarity
messages: Belongs to the TGF-beta family.

244447:LOC103378512
gene id: 244447:LOC103378512
uniprot id: A0A3P8WSU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAPP small subunits family. BET3 subfamily.
messages: Endoplasmic reticulum
messages: cis-Golgi network

244447:LOC103389209
gene id: 244447:LOC103389209
uniprot id: A0A3P8WTT7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 10 family.
messages: Golgi stack membrane

244447:tmem131l
gene id: 244447:tmem131l
uniprot id: A0A3P8UVX0
names: Similarity
messages: Belongs to the TMEM131 family.

244447:shank3
gene id: 244447:shank3
uniprot id: A0A3P8V209
uniprot id: A0A3P8V224
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAGUK family.
messages: Cytoplasm
messages: Postsynaptic density

244447:LOC103399940
gene id: 244447:LOC103399940
uniprot id: A0A3P8UUL6
names: Similarity
messages: Belongs to the TPRG1 family.

244447:mmp2
gene id: 244447:mmp2
uniprot id: A0A3P8V8W0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M10A family.
messages: extracellular matrix

244447:cntd2
gene id: 244447:cntd2
uniprot id: A0A3P8UQP6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cyclin family. Cyclin AB subfamily.
messages: Essential for the control of the cell cycle at the G2/M (mitosis) transition.
messages: Interacts with the CDK1 protein kinase to form a serine/threonine kinase holoenzyme complex also known as maturation promoting factor (MPF). The cyclin subunit imparts substrate specificity to the complex.

244447:LOC103387217
gene id: 244447:LOC103387217
uniprot id: A0A3P8UYC7
names: Subcellular Location Annotation
messages: Membrane

244447:LOC103394231
gene id: 244447:LOC103394231
uniprot id: A0A3P8WA04
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

244447:mtrf1l
gene id: 244447:mtrf1l
uniprot id: A0A3P8UP22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Mitochondrion

244447:LOC103386516
gene id: 244447:LOC103386516
uniprot id: A0A3P8WE32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C26 family.
messages: extracellular space

244447:dph5
gene id: 244447:dph5
uniprot id: A0A3P8UBT8
names: Function
names: Similarity
messages: Belongs to the diphthine synthase family.
messages: S-adenosyl-L-methionine-dependent methyltransferase that catalyzes four methylations of the modified target histidine residue in translation elongation factor 2 (EF-2), to form an intermediate called diphthine methyl ester. The four successive methylation reactions represent the second step of diphthamide biosynthesis.

244447:scnm1
gene id: 244447:scnm1
uniprot id: A0A3P8VNI4
names: Function
names: Subcellular Location Annotation
messages: Nucleus speckle
messages: Plays a role in alternative splicing of pre-mRNAs, possibly by contributing to the selection of non-consensus donor sites.
messages: nucleoplasm

244447:reep2
gene id: 244447:reep2
uniprot id: A0A3P8W1J0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DP1 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

244447:ncapg
gene id: 244447:ncapg
uniprot id: A0A3P8V231
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CND3 (condensin subunit 3) family.
messages: Chromosome

244447:LOC103389240
gene id: 244447:LOC103389240
uniprot id: A0A3P8UMN1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.

244447:LOC103399976
gene id: 244447:LOC103399976
uniprot id: A0A3P8UWZ8
names: Similarity
messages: Belongs to the IUNH family.

244447:LOC103389634
gene id: 244447:LOC103389634
uniprot id: A0A3P8VDF4
names: Similarity
messages: Belongs to the galactose-3-O-sulfotransferase family.

244447:LOC103396166
gene id: 244447:LOC103396166
uniprot id: A0A3P8WRI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

244447:hoxa5
gene id: 244447:hoxa5
uniprot id: A0A3P8W9Y6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

244447:cldn11
gene id: 244447:cldn11
uniprot id: A0A3P8WEK8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

244447:mlf1
gene id: 244447:mlf1
uniprot id: A0A3P8WRV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MLF family.
messages: Cytoplasm

244447:npy
gene id: 244447:npy
uniprot id: A0A3P8VXS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NPY family.
messages: Secreted

244447:LOC103395907
gene id: 244447:LOC103395907
uniprot id: A0A3P8W6L5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

244447:tmem11
gene id: 244447:tmem11
uniprot id: A0A3P8W5C2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM11 family.
messages: Membrane
messages: Mitochondrion inner membrane
messages: Plays a role in mitochondrial morphogenesis.

244447:zdhhc24
gene id: 244447:zdhhc24
uniprot id: A0A3P8V4H6
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

244447:LOC103386459
gene id: 244447:LOC103386459
uniprot id: A0A3P8W3E8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIB subfamily.
messages: Catalyzes the hydrolysis of ATP coupled with the transport of calcium.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

244447:LOC103394067
gene id: 244447:LOC103394067
uniprot id: A0A3P8VT74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPACA4/bouncer family.
messages: Cell membrane
messages: Membrane

244447:LOC103397685
gene id: 244447:LOC103397685
uniprot id: A0A3P8WNV2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complement C6/C7/C8/C9 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

244447:LOC103382827
gene id: 244447:LOC103382827
uniprot id: A0A3P8VQ49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCF family.
messages: Cytoplasm
messages: Secreted
messages: filopodium
messages: lamellipodium

244447:bace1
gene id: 244447:bace1
uniprot id: A0A3P8WBP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A1 family.
messages: Membrane
messages: Membrane raft
messages: Recycling endosome
messages: trans-Golgi network

244447:lrrc8c
gene id: 244447:lrrc8c
uniprot id: A0A3P8VK24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LRRC8 family.
messages: Cell membrane
messages: Membrane

244447:stk33
gene id: 244447:stk33
uniprot id: A0A3P8VLQ3
names: Similarity
messages: Belongs to the protein kinase superfamily.

244447:ctnnal1
gene id: 244447:ctnnal1
uniprot id: A0A3P8VKL1
names: Similarity
messages: Belongs to the vinculin/alpha-catenin family.

244447:LOC103384167
gene id: 244447:LOC103384167
uniprot id: A0A3P8W1Y1
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

244447:rpl5
gene id: 244447:rpl5
uniprot id: A0A3P8WT02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Cytoplasm

244447:LOC103380287
gene id: 244447:LOC103380287
uniprot id: A0A3P8VHM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.
messages: Cell membrane
messages: Membrane

244447:mal2
gene id: 244447:mal2
uniprot id: A0A3P8URY5
names: Subcellular Location Annotation
messages: Membrane

244447:swi5
gene id: 244447:swi5
uniprot id: A0A3P8WFN6
names: Function
names: Similarity
messages: Belongs to the SWI5/SAE3 family.
messages: Component of the swi5-sfr1 complex, a complex required for double-strand break repair via homologous recombination.

244447:hoxd4
gene id: 244447:hoxd4
uniprot id: A0A3P8V8K7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

244447:LOC103397806
gene id: 244447:LOC103397806
uniprot id: A0A3P8WZX3
names: Similarity
messages: Belongs to the CFAP157 family.

244447:LOC103392678
gene id: 244447:LOC103392678
uniprot id: A0A3P8X3P4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the THAP1 family.
messages: DNA-binding transcription regulator that regulates endothelial cell proliferation and G1/S cell-cycle progression. Specifically binds the 5'-[AT]NTNN[GT]GGCA[AGT]-3' core DNA sequence and acts by modulating expression of pRB-E2F cell-cycle target genes.
messages: nucleoplasm

244447:LOC103393908
gene id: 244447:LOC103393908
uniprot id: A0A3P8VDE3
names: Function
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

244447:cpt1a
gene id: 244447:cpt1a
uniprot id: A0A0H3WFW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the carnitine/choline acetyltransferase family.
messages: Membrane
messages: Mitochondrion outer membrane

244447:tmem88b
gene id: 244447:tmem88b
uniprot id: A0A3P8UMW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM88 family.
messages: Membrane

244447:lhpp
gene id: 244447:lhpp
uniprot id: A0A3P8WPV4
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

244447:patl1
gene id: 244447:patl1
uniprot id: A0A3P8VEH6
names: Similarity
messages: Belongs to the PAT1 family.

244447:LOC103390430
gene id: 244447:LOC103390430
uniprot id: A0A097RN11
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

244447:gsdme
gene id: 244447:gsdme
uniprot id: A0A3P8V0S9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gasdermin family.
messages: Cell membrane
messages: Membrane

244447:nudt6
gene id: 244447:nudt6
uniprot id: A0A3P8V3K2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Nudix hydrolase family.
messages: Cytoplasm
messages: May contribute to the regulation of cell proliferation.
messages: Mitochondrion
messages: Monomer and homodimer.
messages: Nucleus

244447:nkiras1
gene id: 244447:nkiras1
uniprot id: A0A3P8VP52
names: Similarity
messages: Belongs to the small GTPase superfamily. Ras family. KappaB-Ras subfamily.

244447:chmp2a
gene id: 244447:chmp2a
uniprot id: A0A3P8W5Q4
names: Similarity
messages: Belongs to the SNF7 family.

244447:LOC103387404
gene id: 244447:LOC103387404
uniprot id: A0A3P8VLX7
uniprot id: A0A3P8VP41
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP dependent phosphorylation of adenosine and other related nucleoside analogs to monophosphate derivatives.
messages: Belongs to the carbohydrate kinase PfkB family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Monomer.
messages: Nucleus

244447:slc12a8
gene id: 244447:slc12a8
uniprot id: A0A3P8VXF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC12A transporter family.
messages: Membrane

244447:atg9a
gene id: 244447:atg9a
uniprot id: A0A3P8UUY2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATG9 family.
messages: Membrane
messages: Phospholipid scramblase involved in autophagy. Cycles between the preautophagosomal structure/phagophore assembly site (PAS) and the cytoplasmic vesicle pool and supplies membrane for the growing autophagosome. Lipid scramblase activity plays a key role in preautophagosomal structure/phagophore assembly by distributing the phospholipids that arrive through ATG2 from the cytoplasmic to the luminal leaflet of the bilayer, thereby driving autophagosomal membrane expansion.
messages: Preautophagosomal structure membrane

244447:LOC103395653
gene id: 244447:LOC103395653
uniprot id: A0A3P8V4A6
names: Similarity
messages: Belongs to the FMO family.

244447:tradd
gene id: 244447:tradd
uniprot id: A0A3P8UKA5
names: Subcellular Location Annotation
messages: Nucleus
messages: cytoskeleton

244447:LOC103385054
gene id: 244447:LOC103385054
uniprot id: A0A3P8WP60
names: Subcellular Location Annotation
messages: Nucleus

244447:LOC103384913
gene id: 244447:LOC103384913
uniprot id: A0A3P8V3E9
names: Similarity
messages: Belongs to the SZRD1 family.

244447:LOC103385983
gene id: 244447:LOC103385983
uniprot id: A0A3P8UCY8
names: Function
names: Similarity
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.

244447:ipo5
gene id: 244447:ipo5
uniprot id: A0A3P8USX9
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

244447:LOC103382351
gene id: 244447:LOC103382351
uniprot id: A0A3P8UKX4
names: Similarity
messages: Belongs to the TECPR1 family.

244447:spon1
gene id: 244447:spon1
uniprot id: A0A3P8WC31
names: Subcellular Location Annotation
messages: extracellular matrix

244447:LOC103391697
gene id: 244447:LOC103391697
uniprot id: A0A3P8W5D2
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

244447:armc1
gene id: 244447:armc1
uniprot id: A0A3P8W9T2
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In association with mitochondrial contact site and cristae organizing system (MICOS) complex components and mitochondrial outer membrane sorting assembly machinery (SAM) complex components may regulate mitochondrial dynamics playing a role in determining mitochondrial length, distribution and motility.
messages: Membrane
messages: Mitochondrion outer membrane

244447:vangl2
gene id: 244447:vangl2
uniprot id: A0A3P8X2J4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Vang family.
messages: Cell membrane
messages: Membrane

244447:LOC103388283
gene id: 244447:LOC103388283
uniprot id: A0A3P8USV1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxisomal membrane protein PXMP2/4 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

244447:cnmd
gene id: 244447:cnmd
uniprot id: A0A3P8WVM9
names: Similarity
messages: Belongs to the chondromodulin-1 family.

244447:LOC103378129
gene id: 244447:LOC103378129
uniprot id: A0A3P8VP34
names: Similarity
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family.

244447:mat2a
gene id: 244447:mat2a
uniprot id: A0A3P8UPM1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit. The potassium ion interacts primarily with the substrate.
messages: Binds 2 magnesium ions per subunit. The magnesium ions interact primarily with the substrate.
messages: Catalyzes the formation of S-adenosylmethionine from methionine and ATP.

244447:LOC103392521
gene id: 244447:LOC103392521
uniprot id: A0A3P8X2X3
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

244447:atp6v0b
gene id: 244447:atp6v0b
uniprot id: A0A3P8VUQ1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the V-ATPase proteolipid subunit family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Proton-conducting pore forming of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex. The V1 complex consists of three catalytic AB heterodimers that form a heterohexamer, three peripheral stalks each consisting of EG heterodimers, one central rotor including subunits D and F, and the regulatory subunits C and H. The proton translocation complex V0 consists of the proton transport subunit a, a ring of proteolipid subunits c9c'', rotary subunit d, subunits e and f, and the accessory subunits.
messages: clathrin-coated vesicle membrane

244447:dhrs7b
gene id: 244447:dhrs7b
uniprot id: A0A3P8W7Z0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

244447:LOC103395888
gene id: 244447:LOC103395888
uniprot id: A0A3P8W2Y7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tim44 family.
messages: Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner.
messages: Mitochondrion inner membrane

244447:LOC103382427
gene id: 244447:LOC103382427
uniprot id: A0A3P8UXG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SAM50/omp85 family.
messages: Mitochondrion outer membrane

244447:ehf
gene id: 244447:ehf
uniprot id: A0A3P8WAB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

244447:spry1
gene id: 244447:spry1
uniprot id: A0A3P8UX82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sprouty family.
messages: Cytoplasm
messages: Membrane

244447:LOC103398287
gene id: 244447:LOC103398287
uniprot id: A0A3P8WH76
uniprot id: A0A3P8WH81
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

244447:LOC103389081
gene id: 244447:LOC103389081
uniprot id: A0A3P8WHI1
names: Similarity
messages: Belongs to the CD36 family.

244447:LOC103397189
gene id: 244447:LOC103397189
uniprot id: A0A3P8W9P3
names: Function
names: Subcellular Location Annotation
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Nucleus

244447:gria2
gene id: 244447:gria2
uniprot id: A0A3P8URZ9
uniprot id: A0A3P8UUA9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

244447:cdc37
gene id: 244447:cdc37
uniprot id: A0A3P8X1Y2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDC37 family.
messages: Cytoplasm

244447:tmem41b
gene id: 244447:tmem41b
uniprot id: A0A3P8VNC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM41 family.
messages: Membrane

244447:LOC103389872
gene id: 244447:LOC103389872
uniprot id: A0A3P8V7C8
names: Caution
names: Similarity
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

244447:plxna4
gene id: 244447:plxna4
uniprot id: A0A3P8V9K4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the plexin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

244447:ppm1a
gene id: 244447:ppm1a
uniprot id: A0A3P8UNJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PP2C family.
messages: Membrane
messages: cytosol

244447:ndor1
gene id: 244447:ndor1
uniprot id: A0A3P8WRK4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NADPH-dependent diflavin oxidoreductase NDOR1 family.
messages: In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
messages: In the N-terminal section; belongs to the flavodoxin family.
messages: Interacts with CIAPIN1; as part of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NADPH-dependent reductase which is a central component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery. Transfers electrons from NADPH via its FAD and FMN prosthetic groups to the [2Fe-2S] cluster of CIAPIN1, another key component of the CIA machinery. In turn, this reduced cluster provides electrons for assembly of cytosolic iron-sulfur cluster proteins. It can also reduce the [2Fe-2S] cluster of CISD1 and activate this protein implicated in Fe/S cluster repair.
messages: perinuclear region

244447:LOC103379072
gene id: 244447:LOC103379072
uniprot id: A0A3P8VMR5
names: Similarity
names: Subunit
messages: Belongs to the group II decarboxylase family.
messages: Homodimer.

244447:copz1
gene id: 244447:copz1
uniprot id: A0A3P8VES5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adaptor complexes small subunit family.
messages: COPI-coated vesicle membrane
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.
messages: The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properties with the coatomer complex.

244447:LOC103379085
gene id: 244447:LOC103379085
uniprot id: A0A3P8VZN4
names: Subcellular Location Annotation
messages: Membrane

244447:cers5
gene id: 244447:cers5
uniprot id: A0A3P8WWC5
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Nucleus

244447:LOC103383764
gene id: 244447:LOC103383764
uniprot id: A0A3P8V9U4
uniprot id: A0A3P8VC30
names: Similarity
messages: Belongs to the JHDM3 histone demethylase family.

244447:LOC103388733
gene id: 244447:LOC103388733
uniprot id: A0A3P8VPN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CALHM family.
messages: Membrane

244447:dym
gene id: 244447:dym
uniprot id: A0A3P8WZZ5
names: Similarity
messages: Belongs to the dymeclin family.

244447:prune1
gene id: 244447:prune1
uniprot id: A0A3P8UKW9
names: Similarity
messages: Belongs to the PPase class C family. Prune subfamily.

244447:LOC103390765
gene id: 244447:LOC103390765
uniprot id: A0A3P8V3Z6
names: Subcellular Location Annotation
messages: Nucleus

244447:LOC103383433
gene id: 244447:LOC103383433
uniprot id: A0A3P8UGU9
names: Subcellular Location Annotation
messages: Membrane

244447:LOC103384878
gene id: 244447:LOC103384878
uniprot id: A0A3P8UW99
names: Similarity
messages: Belongs to the protein kinase superfamily.

244447:cep19
gene id: 244447:cep19
uniprot id: A0A3P8UVD3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CEP19 family.
messages: centriole
messages: cilium basal body
messages: spindle pole

244447:LOC103382630
gene id: 244447:LOC103382630
uniprot id: A0A3P8V5J2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

244447:LOC103397272
gene id: 244447:LOC103397272
uniprot id: A0A3P8WNE3
names: Similarity
messages: Belongs to the WD repeat coronin family.

244447:LOC103380923
gene id: 244447:LOC103380923
uniprot id: A0A3P8X0K9
uniprot id: A0A3P8X475
uniprot id: A0A3P8X5C6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase C2 family.
messages: Calcium-regulated non-lysosomal thiol-protease.
messages: Cytoplasm
messages: Homodimer.
messages: nucleolus

244447:LOC103394421
gene id: 244447:LOC103394421
uniprot id: A0A3P8WR66
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NKD family.
messages: Cell autonomous antagonist of the canonical Wnt signaling pathway.
messages: Cell membrane
messages: Cytoplasm
messages: Membrane

244447:LOC103389742
gene id: 244447:LOC103389742
uniprot id: A0A3P8W3E0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

244447:cope
gene id: 244447:cope
uniprot id: A0A3P8W6C7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the COPE family.
messages: Cytoplasm
messages: Membrane
messages: Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.
messages: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. The coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.

244447:LOC103387940
gene id: 244447:LOC103387940
uniprot id: A0A3P8X0P6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the natriuretic peptide family.
messages: Exhibits natriuretic and vasodepressant activity. Has cGMP-stimulating activity. May help to regulate body fluid homeostasis in a variety of aquatic environments.
messages: Secreted

244447:ap2s1
gene id: 244447:ap2s1
uniprot id: A0A3P8VEU3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Adaptor protein complex 2 (AP-2) is a heterotetramer composed of two large adaptins (alpha-type subunit AP2A1 or AP2A2 and beta-type subunit AP2B1), a medium adaptin (mu-type subunit AP2M1) and a small adaptin (sigma-type subunit AP2S1).
messages: Belongs to the adaptor complexes small subunit family.
messages: Cell membrane
messages: coated pit

244447:LOC103385650
gene id: 244447:LOC103385650
uniprot id: A0A3P8X779
names: Similarity
messages: Belongs to the glycosyl hydrolase 56 family.

244447:LOC103376753
gene id: 244447:LOC103376753
uniprot id: A0A3P8VDM5
names: Caution
names: Similarity
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

244447:srp54
gene id: 244447:srp54
uniprot id: A0A3P8W1B0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Component of a signal recognition particle (SRP) complex that consists of a 7SL RNA molecule of 300 nucleotides and six protein subunits: SRP72, SRP68, SRP54, SRP19, SRP14 and SRP9.
messages: Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER). Binds to the signal sequence of presecretory proteins when they emerge from the ribosomes.
messages: Cytoplasm
messages: Has a two domain structure: the G-domain binds GTP; the M-domain binds the 7S RNA in presence of SRP19 and also binds the signal sequence.
messages: Nucleus speckle
messages: Signal recognition particle consists of a 7S RNA molecule and at least six protein subunits.

244447:tmem9b
gene id: 244447:tmem9b
uniprot id: A0A3P8VLB7
names: Similarity
messages: Belongs to the TMEM9 family.

244447:gadd45gip1
gene id: 244447:gadd45gip1
uniprot id: A0A3P8W097
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a negative regulator of G1 to S cell cycle phase progression by inhibiting cyclin-dependent kinases. Inhibitory effects are additive with GADD45 proteins but occurs also in the absence of GADD45 proteins. Acts as a repressor of the orphan nuclear receptor NR4A1 by inhibiting AB domain-mediated transcriptional activity. May be involved in the hormone-mediated regulation of NR4A1 transcriptional activity. May play a role in mitochondrial protein synthesis.
messages: Belongs to the mitochondrion-specific ribosomal protein mL64 family.
messages: Mitochondrion
messages: Nucleus

244447:LOC103390344
gene id: 244447:LOC103390344
uniprot id: A0A3P8X3X3
names: Function
names: Similarity
messages: Belongs to the 5'-AMP-activated protein kinase beta subunit family.
messages: Non-catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton; probably by indirectly activating myosin. Beta non-catalytic subunit acts as a scaffold on which the AMPK complex assembles, via its C-terminus that bridges alpha (PRKAA1 or PRKAA2) and gamma subunits (PRKAG1, PRKAG2 or PRKAG3).

244447:cenpj
gene id: 244447:cenpj
uniprot id: A0A3P8VML7
names: Similarity
messages: Belongs to the TCP10 family.

244447:LOC103386550
gene id: 244447:LOC103386550
uniprot id: A0A3P8WF75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the potassium channel family. A (Shaker) (TC 1.A.1.2) subfamily. Kv1.2/KCNA2 sub-subfamily.
messages: Cell membrane
messages: Membrane

244447:LOC103395031
gene id: 244447:LOC103395031
uniprot id: A0A3P8WY27
names: Similarity
messages: Belongs to the dapper family.

244447:LOC103384209
gene id: 244447:LOC103384209
uniprot id: A0A3P8W4C1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

244447:LOC103378893
gene id: 244447:LOC103378893
uniprot id: A0A3P8V8S9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CENP-Q/OKP1 family.
messages: Nucleus

244447:acvr1
gene id: 244447:acvr1
uniprot id: A0A3P8VSI6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Membrane

244447:LOC103393351
gene id: 244447:LOC103393351
uniprot id: A0A3P8VBV4
names: Subcellular Location Annotation
messages: Membrane

244447:eva1c
gene id: 244447:eva1c
uniprot id: A0A3P8WUW1
names: Similarity
messages: Belongs to the EVA1 family.

244447:atg4c
gene id: 244447:atg4c
uniprot id: A0A3P8WNS6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C54 family.
messages: Cysteine protease that plays a key role in autophagy by mediating both proteolytic activation and delipidation of ATG8 family proteins.
messages: Cytoplasm

244447:LOC103384793
gene id: 244447:LOC103384793
uniprot id: A0A3P8WI74
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calsequestrin family.
messages: Calsequestrin is a high-capacity, moderate affinity, calcium-binding protein and thus acts as an internal calcium store in muscle.
messages: Sarcoplasmic reticulum lumen

244447:ppp1r21
gene id: 244447:ppp1r21
uniprot id: A0A3P8W1K7
names: Subcellular Location Annotation
messages: Early endosome
messages: Endosome

244447:mpp4
gene id: 244447:mpp4
uniprot id: A0A3P8VAF1
names: Similarity
messages: Belongs to the MAGUK family.

244447:mtmr4
gene id: 244447:mtmr4
uniprot id: A0A3P8VU21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.
messages: Cytoplasm
messages: Membrane

244447:adi1
gene id: 244447:adi1
uniprot id: A0A3P8U9P2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acireductone dioxygenase (ARD) family.
messages: Binds either 1 Fe or Ni cation per monomer. Iron-binding promotes an acireductone dioxygenase reaction producing 2-keto-4-methylthiobutyrate, while nickel-binding promotes an acireductone dioxygenase reaction producing 3-(methylsulfanyl)propanoate.
messages: Catalyzes 2 different reactions between oxygen and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.
messages: Nucleus

244447:alkbh5
gene id: 244447:alkbh5
uniprot id: A0A3P8UMD4
names: Subcellular Location Annotation
names: Subunit
messages: Monomer.
messages: Nucleus speckle

244447:flcn
gene id: 244447:flcn
uniprot id: A0A3P8WVL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the folliculin family.
messages: Lysosome membrane
messages: Membrane
messages: Nucleus
messages: centrosome
messages: cilium
messages: cytosol
messages: spindle

244447:gla
gene id: 244447:gla
uniprot id: A0A3P8UR54
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycosyl hydrolase 27 family.
messages: Homodimer.
messages: Lysosome

244447:LOC103394540
gene id: 244447:LOC103394540
uniprot id: A0A3P8V7E6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

244447:got2
gene id: 244447:got2
uniprot id: A0A3P8V4D3
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.
messages: In eukaryotes there are cytoplasmic, mitochondrial and chloroplastic isozymes.

244447:LOC103389519
gene id: 244447:LOC103389519
uniprot id: A0A3P8V1T2
names: Similarity
messages: Belongs to the glutaminase family.

244447:LOC103388561
gene id: 244447:LOC103388561
uniprot id: A0A3P8VHB7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the membrane-bound acyltransferase family. Sterol o-acyltransferase subfamily.
messages: Endoplasmic reticulum membrane
messages: Homodimer or homotetramer; both forms have similar enzymatic activities.
messages: Membrane

244447:LOC103377360
gene id: 244447:LOC103377360
uniprot id: A0A3P8WUS6
names: Function
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

244447:LOC103396904
gene id: 244447:LOC103396904
uniprot id: A0A3P8VNW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Orai family.
messages: Membrane

244447:LOC103395870
gene id: 244447:LOC103395870
uniprot id: A0A3P8W137
names: Subcellular Location Annotation
messages: Membrane

244447:LOC103385772
gene id: 244447:LOC103385772
uniprot id: A0A3P8UP11
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

244447:lpin1
gene id: 244447:lpin1
uniprot id: A0A3P8UL31
names: Similarity
messages: Belongs to the lipin family.

244447:LOC103377173
gene id: 244447:LOC103377173
uniprot id: A0A3P8WCK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

244447:cops4
gene id: 244447:cops4
uniprot id: A0A3P8VVD8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSN4 family.
messages: Nucleus
messages: Vesicle
messages: synaptic vesicle

244447:chsy1
gene id: 244447:chsy1
uniprot id: A0A3P8VH60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chondroitin N-acetylgalactosaminyltransferase family.
messages: Golgi stack membrane
messages: Membrane

244447:pdcl3
gene id: 244447:pdcl3
uniprot id: A0A3P8US48
names: Similarity
messages: Belongs to the phosducin family.

244447:LOC103381749
gene id: 244447:LOC103381749
uniprot id: A0A3P8VZR8
names: Similarity
messages: Belongs to the IL-6 superfamily.

244447:LOC103389840
gene id: 244447:LOC103389840
uniprot id: A0A3P8VFK5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

244447:hook3
gene id: 244447:hook3
uniprot id: A0A3P8UW84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the hook family.
messages: cytoskeleton

244447:manf
gene id: 244447:manf
uniprot id: A0A3P8V2L4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ARMET family.
messages: Secreted

244447:LOC103389560
gene id: 244447:LOC103389560
uniprot id: A0A3P8V4X9
names: Subcellular Location Annotation
messages: Nucleus

244447:LOC103392251
gene id: 244447:LOC103392251
uniprot id: A0A3P8VLQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uricase family.
messages: Catalyzes the oxidation of uric acid to 5-hydroxyisourate, which is further processed to form (S)-allantoin.
messages: Peroxisome

244447:l1cam
gene id: 244447:l1cam
uniprot id: A0A3P8UIN6
uniprot id: A0A3P8UK85
uniprot id: A0A3P8UPT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. L1/neurofascin/NgCAM family.
messages: Membrane

244447:LOC103378568
gene id: 244447:LOC103378568
uniprot id: A0A3P8WTN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM TET family.
messages: Nucleus

244447:LOC103389763
gene id: 244447:LOC103389763
uniprot id: A0A3P8W7Y1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calsequestrin family.
messages: Calsequestrin is a high-capacity, moderate affinity, calcium-binding protein and thus acts as an internal calcium store in muscle.
messages: Sarcoplasmic reticulum lumen

244447:mettl1
gene id: 244447:mettl1
uniprot id: A0A3P8UW79
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Forms a complex with WDR4.
messages: Nucleus

244447:LOC103396215
gene id: 244447:LOC103396215
uniprot id: A0A3P8VK66
names: Subcellular Location Annotation
messages: Membrane

244447:LOC103381587
gene id: 244447:LOC103381587
uniprot id: A0A3P8VDX7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIA subfamily.
messages: Catalyzes the hydrolysis of ATP coupled with the transport of calcium.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Sarcoplasmic reticulum membrane

244447:LOC103384244
gene id: 244447:LOC103384244
uniprot id: A0A3P8WEW6
names: Subcellular Location Annotation
messages: Cytoplasm

244447:LOC103392936
gene id: 244447:LOC103392936
uniprot id: A0A3P8VXC5
uniprot id: A0A3P8VZY7
uniprot id: A0A3P8W2T8
uniprot id: A0A3P8W2V3
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.

244447:qtrt2
gene id: 244447:qtrt2
uniprot id: A0A3P8WMJ0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family. QTRT2 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Heterodimer of a catalytic subunit QTRT1 and an accessory subunit QTRT2.
messages: Mitochondrion outer membrane
messages: Non-catalytic subunit of the queuine tRNA-ribosyltransferase (TGT) that catalyzes the base-exchange of a guanine (G) residue with queuine (Q) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).

244447:gdpd5
gene id: 244447:gdpd5
uniprot id: A0A3P8UTA9
uniprot id: A0A3P8UUM3
names: Similarity
messages: Belongs to the glycerophosphoryl diester phosphodiesterase family.

244447:LOC103382102
gene id: 244447:LOC103382102
uniprot id: A0A3P8WZ53
names: Subcellular Location Annotation
messages: Nucleus

244447:entpd5
gene id: 244447:entpd5
uniprot id: A0A3P8UIQ3
names: Similarity
messages: Belongs to the GDA1/CD39 NTPase family.

244447:mon1a
gene id: 244447:mon1a
uniprot id: A0A3P8VBM3
names: Function
names: Similarity
messages: Belongs to the MON1/SAND family.
messages: Plays an important role in membrane trafficking through the secretory apparatus.

244447:LOC103380784
gene id: 244447:LOC103380784
uniprot id: A0A3P8WVT8
names: Similarity
messages: Belongs to the FAX family.

244447:cryba4
gene id: 244447:cryba4
uniprot id: A0A3P8VS80
names: Function
names: Similarity
names: Subunit
messages: Belongs to the beta/gamma-crystallin family.
messages: Crystallins are the dominant structural components of the vertebrate eye lens.
messages: Homo/heterodimer, or complexes of higher-order. The structure of beta-crystallin oligomers seems to be stabilized through interactions between the N-terminal arms.

244447:paxbp1
gene id: 244447:paxbp1
uniprot id: A0A3P8VJY5
names: Similarity
messages: Belongs to the GCF family.

244447:LOC103385165
gene id: 244447:LOC103385165
uniprot id: A0A3P8VMM8
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

244447:LOC103392118
gene id: 244447:LOC103392118
uniprot id: A0A3P8VRQ1
names: Subcellular Location Annotation
messages: Membrane

244447:tma16
gene id: 244447:tma16
uniprot id: A0A3P8UX13
names: Function
names: Similarity
names: Subunit
messages: Associates with pre-60S ribosomal particles.
messages: Belongs to the TMA16 family.
messages: Involved in the biogenesis of the 60S ribosomal subunit in the nucleus.

244447:atrn
gene id: 244447:atrn
uniprot id: A0A3P8WA33
uniprot id: A0A3P8WCZ2
uniprot id: A0A3P8WFH9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

244447:LOC103382404
gene id: 244447:LOC103382404
uniprot id: A0A3P8UNE9
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

244447:ppp4r2
gene id: 244447:ppp4r2
uniprot id: A0A3P8VA31
names: Similarity
messages: Belongs to the PPP4R2 family.

244447:foxb1
gene id: 244447:foxb1
uniprot id: A0A3P8UTK0
names: Subcellular Location Annotation
messages: Nucleus

244447:LOC103393601
gene id: 244447:LOC103393601
uniprot id: A0A3P8W335
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

244447:agbl5
gene id: 244447:agbl5
uniprot id: A0A3P8WU89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M14 family.
messages: Midbody
messages: Nucleus
messages: cytosol
messages: spindle

244447:mfsd1
gene id: 244447:mfsd1
uniprot id: A0A3P8VCX8
uniprot id: A0A3P8VL77
names: Subcellular Location Annotation
messages: Membrane

244447:smc2
gene id: 244447:smc2
uniprot id: A0A3P8VCI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMC family. SMC2 subfamily.
messages: Chromosome
messages: Nucleus

244447:LOC103397782
gene id: 244447:LOC103397782
uniprot id: A0A3P8WUY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Membrane

244447:LOC103378882
gene id: 244447:LOC103378882
uniprot id: A0A3P8V5T4
names: Similarity
messages: Belongs to the peptidase S10 family.

244447:arl2
gene id: 244447:arl2
uniprot id: A0A3P8WHU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: centrosome

244447:LOC103387819
gene id: 244447:LOC103387819
uniprot id: A0A3P8WNI2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NECAP family.
messages: Involved in endocytosis.
messages: clathrin-coated vesicle membrane

244447:LOC103380556
gene id: 244447:LOC103380556
uniprot id: A0A3P8WDZ4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LDH/MDH superfamily. LDH family.
messages: Cytoplasm
messages: Homotetramer.

244447:LOC103379770
gene id: 244447:LOC103379770
uniprot id: A0A3P8X478
names: Similarity
messages: Belongs to the RPGRIP1 family.

244447:ormdl2
gene id: 244447:ormdl2
uniprot id: A0A3P8X6P7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ORM family.
messages: Membrane
messages: Negative regulator of sphingolipid synthesis.

244447:dnajc24
gene id: 244447:dnajc24
uniprot id: A0A3P8WZS7
names: Similarity
messages: Belongs to the DPH4 family.

244447:stat3
gene id: 244447:stat3
uniprot id: A0A3P8WJG6
uniprot id: A0A3P8WMU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transcription factor STAT family.
messages: Cytoplasm
messages: Nucleus

244447:LOC103381513
gene id: 244447:LOC103381513
uniprot id: A0A3P8VGE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Elbow/Noc family.
messages: Nucleus

244447:LOC103390114
gene id: 244447:LOC103390114
uniprot id: A0A3P8WJS4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chemokine-like receptor (CMKLR) family.
messages: Cell membrane
messages: Membrane

244447:med6
gene id: 244447:med6
uniprot id: A0A3P8VFZ8
uniprot id: A0A3P8VIV3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 6 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

244447:phox2a
gene id: 244447:phox2a
uniprot id: A0A3P8WY77
names: Subcellular Location Annotation
messages: Nucleus

244447:pqlc3
gene id: 244447:pqlc3
uniprot id: A0A3P8WIW3
names: Subcellular Location Annotation
messages: Membrane

244447:idh2
gene id: 244447:idh2
uniprot id: A0A3P8W6R0
names: Cofactor
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

244447:olah
gene id: 244447:olah
uniprot id: A0A3P8VPT6
names: Similarity
messages: Belongs to the thioesterase family.

244447:coq4
gene id: 244447:coq4
uniprot id: A0A3P8WN18
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the COQ4 family.
messages: Component of a multi-subunit COQ enzyme complex, composed of at least COQ3, COQ4, COQ5, COQ6, COQ7 and COQ9.
messages: Component of the coenzyme Q biosynthetic pathway. May play a role in organizing a multi-subunit COQ enzyme complex required for coenzyme Q biosynthesis. Required for steady-state levels of other COQ polypeptides.
messages: Mitochondrion inner membrane

244447:LOC103394806
gene id: 244447:LOC103394806
uniprot id: A0A3P8W0E0
names: Subcellular Location Annotation
messages: Membrane

244447:LOC103378153
gene id: 244447:LOC103378153
uniprot id: A0A3P8VM34
names: Similarity
messages: Belongs to the band 7/mec-2 family.

244447:hbp1
gene id: 244447:hbp1
uniprot id: A0A3P8UWU9
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Transcriptional repressor that binds to the promoter region of target genes. Plays a role in the regulation of the cell cycle and of the Wnt pathway. Binds preferentially to the sequence 5'-TTCATTCATTCA-3'. Binding to the histone H1.0 promoter is enhanced by interaction with RB1. Disrupts the interaction between DNA and TCF4.

244447:LOC103379386
gene id: 244447:LOC103379386
uniprot id: A0A3P8W3W8
names: Subcellular Location Annotation
messages: Nucleus

244447:prmt7
gene id: 244447:prmt7
uniprot id: A0A3P8UKW7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA), with a preference for the formation of MMA. Specifically mediates the symmetrical dimethylation of arginine residues in the small nuclear ribonucleoproteins Sm D1 (SNRPD1) and Sm D3 (SNRPD3); such methylation being required for the assembly and biogenesis of snRNP core particles. Specifically mediates the symmetric dimethylation of histone H4 'Arg-3' to form H4R3me2s. Plays a role in gene imprinting by being recruited by CTCFL at the H19 imprinted control region (ICR) and methylating histone H4 to form H4R3me2s, possibly leading to recruit DNA methyltransferases at these sites. May also play a role in embryonic stem cell (ESC) pluripotency. Also able to mediate the arginine methylation of histone H2A and myelin basic protein (MBP) in vitro; the relevance of such results is however unclear in vivo.
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. PRMT7 subfamily.
messages: Nucleus
messages: cytosol

244447:LOC103398029
gene id: 244447:LOC103398029
uniprot id: A0A3P8VSZ6
names: Similarity
messages: Belongs to the serpin family.

244447:LOC103379355
gene id: 244447:LOC103379355
uniprot id: A0A3P8UQ98
names: Subcellular Location Annotation
messages: Nucleus

244447:LOC103393526
gene id: 244447:LOC103393526
uniprot id: A0A3P8W171
names: Cofactor
names: PTM
names: Similarity
messages: Belongs to the copper/topaquinone oxidase family.
messages: Contains 1 topaquinone per subunit.
messages: Topaquinone (TPQ) is generated by copper-dependent autoxidation of a specific tyrosyl residue.

244447:xpnpep2
gene id: 244447:xpnpep2
uniprot id: A0A3P8UPR7
names: Similarity
messages: Belongs to the peptidase M24B family.

244447:apmap
gene id: 244447:apmap
uniprot id: A0A3P8UY65
names: Similarity
messages: Belongs to the strictosidine synthase family.

244447:dis3
gene id: 244447:dis3
uniprot id: A0A3P8UQP5
names: Similarity
messages: Belongs to the RNR ribonuclease family.

244447:LOC103386155
gene id: 244447:LOC103386155
uniprot id: A0A3P8UZN7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase.

244447:tmem138
gene id: 244447:tmem138
uniprot id: A0A3P8V941
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM138 family.
messages: Membrane
messages: Required for ciliogenesis.
messages: Vacuole membrane
messages: cilium

244447:ptdss1
gene id: 244447:ptdss1
uniprot id: A0A3P8UUI3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphatidyl serine synthase family.
messages: Catalyzes a base-exchange reaction in which the polar head group of phosphatidylethanolamine (PE) is replaced by L-serine.
messages: Endoplasmic reticulum membrane
messages: Membrane

244447:man2a2
gene id: 244447:man2a2
uniprot id: A0A3P8W4V4
names: Cofactor
names: Similarity
messages: Belongs to the glycosyl hydrolase 38 family.
messages: Binds 1 zinc ion per subunit.

244447:sumo1
gene id: 244447:sumo1
uniprot id: A0A3P8V3Z3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ubiquitin family. SUMO subfamily.
messages: Nucleus

244447:LOC103386565
gene id: 244447:LOC103386565
uniprot id: A0A3P8WHG5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the F-actin-capping protein alpha subunit family.
messages: F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.
messages: Heterodimer of an alpha and a beta subunit.

244447:LOC103391980
gene id: 244447:LOC103391980
uniprot id: A0A3P8VG29
names: Similarity
messages: Belongs to the ZC3H12 family.

244447:LOC103391409
gene id: 244447:LOC103391409
uniprot id: A0A3P8WUK7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the V-ATPase e1/e2 subunit family.
messages: Membrane
messages: Subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.

244447:mdga2
gene id: 244447:mdga2
uniprot id: A0A3P8UHP9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

244447:parl
gene id: 244447:parl
uniprot id: A0A3P8WEV8
names: Subcellular Location Annotation
messages: Membrane

244447:LOC103388119
gene id: 244447:LOC103388119
uniprot id: A0A3P8UH18
names: Subcellular Location Annotation
messages: Membrane

244447:LOC103379971
gene id: 244447:LOC103379971
uniprot id: A0A3P8USS0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Heterooligomer of subunits alpha (IDH3A), beta (IDH3B), and gamma (IDH3G) in the apparent ratio of 2:1:1. The heterodimer containing one IDH3A and one IDH3B subunit and the heterodimer containing one IDH3A and one IDH3G subunit assemble into a heterotetramer (which contains two subunits of IDH3A, one of IDH3B and one of IDH3G) and further into the heterooctamer.
messages: Mitochondrion

244447:LOC103395466
gene id: 244447:LOC103395466
uniprot id: A0A0H3WEU7
names: Function
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and thereby links the glycolytic pathway to the tricarboxylic cycle.

244447:nubp1
gene id: 244447:nubp1
uniprot id: A0A3P8WPG9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP1/NBP35 subfamily.
messages: Binds 4 [4Fe-4S] clusters per heterotetramer. Contains two stable clusters in the N-termini of NUBP1 and two labile, bridging clusters between subunits of the NUBP1-NUBP2 heterotetramer.
messages: Cell projection
messages: Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NUBP1-NUBP2 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins.
messages: Cytoplasm
messages: Heterotetramer of 2 NUBP1 and 2 NUBP2 chains.

244447:abi2
gene id: 244447:abi2
uniprot id: A0A3P8V876
uniprot id: A0A3P8VAS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABI family.
messages: cytoskeleton
messages: filopodium
messages: lamellipodium

244447:LOC103386842
gene id: 244447:LOC103386842
uniprot id: A0A3P8X2K0
names: Similarity
messages: Belongs to the proteasome inhibitor PI31 family.

244447:LOC103395411
gene id: 244447:LOC103395411
uniprot id: A0A3P8WM21
names: Similarity
messages: Belongs to the WD repeat G protein beta family.

244447:LOC103382060
gene id: 244447:LOC103382060
uniprot id: A0A3P8WY93
names: Similarity
names: Subunit
messages: Belongs to the histone H3 family.
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

244447:tmco1
gene id: 244447:tmco1
uniprot id: A0A3P8ULB9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMCO1 family.
messages: Calcium-selective channel required to prevent calcium stores from overfilling.
messages: Endoplasmic reticulum membrane
messages: Membrane

244447:tns4
gene id: 244447:tns4
uniprot id: A0A3P8WAK3
names: Similarity
messages: Belongs to the PTEN phosphatase protein family.

244447:gclm
gene id: 244447:gclm
uniprot id: A0A3P8X3E4
names: Similarity
names: Subunit
messages: Belongs to the aldo/keto reductase family. Glutamate--cysteine ligase light chain subfamily.
messages: Heterodimer of a catalytic heavy chain and a regulatory light chain.

244447:LOC103377809
gene id: 244447:LOC103377809
uniprot id: A0A3P8V121
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC12A transporter family.
messages: Membrane

244447:LOC103396130
gene id: 244447:LOC103396130
uniprot id: A0A3P8WN26
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Melanosome
messages: Membrane
messages: SNARE involved in targeting and fusion of ER-derived transport vesicles with the Golgi complex as well as Golgi-derived retrograde transport vesicles with the ER.
messages: cis-Golgi network membrane
messages: trans-Golgi network membrane

244447:pigu
gene id: 244447:pigu
uniprot id: A0A3P8UJ01
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGU family.
messages: Component of the GPI transamidase complex. May be involved in the recognition of either the GPI attachment signal or the lipid portion of GPI.
messages: Endoplasmic reticulum membrane
messages: Membrane

244447:LOC103396358
gene id: 244447:LOC103396358
uniprot id: A0A3P8VTY9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G protein gamma family.
messages: Cell membrane
messages: G proteins are composed of 3 units; alpha, beta and gamma.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

244447:thbs2
gene id: 244447:thbs2
uniprot id: A0A3P8V1W0
uniprot id: A0A3P8V840
names: Caution
names: Similarity
messages: Belongs to the thrombospondin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

244447:lamp5
gene id: 244447:lamp5
uniprot id: A0A3P8UR94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LAMP family.
messages: Endosome membrane

244447:LOC103396193
gene id: 244447:LOC103396193
uniprot id: A0A3P8WRZ2
names: Subcellular Location Annotation
messages: Endosome membrane
messages: Membrane

244447:slc39a12
gene id: 244447:slc39a12
uniprot id: A0A3P8UK83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZIP transporter (TC 2.A.5) family.
messages: Membrane

244447:LOC103380399
gene id: 244447:LOC103380399
uniprot id: A0A3P8VQJ9
names: Similarity
messages: Belongs to the mTERF family.

244447:txnl4b
gene id: 244447:txnl4b
uniprot id: A0A3P8V2I3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DIM1 family.
messages: Nucleus
messages: Plays role in pre-mRNA splicing.

244447:LOC103381429
gene id: 244447:LOC103381429
uniprot id: A0A3P8V6W9
names: Caution
names: Similarity
messages: Belongs to the neuregulin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

244447:gpr182
gene id: 244447:gpr182
uniprot id: A0A3P8VGZ1
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

244447:spsb1
gene id: 244447:spsb1
uniprot id: A0A3P8V752
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPSB family.
messages: Cytoplasm

244447:LOC103382959
gene id: 244447:LOC103382959
uniprot id: A0A3P8WD46
names: Similarity
messages: Belongs to the DENND11 family.

244447:LOC103386925
gene id: 244447:LOC103386925
uniprot id: A0A3P8UFY8
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family.

244447:LOC103394989
gene id: 244447:LOC103394989
uniprot id: A0A3P8WN27
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELL/occludin family.
messages: Cell membrane
messages: May play a role in the formation and regulation of the tight junction (TJ) paracellular permeability barrier.
messages: Membrane
messages: tight junction

244447:prkacb
gene id: 244447:prkacb
uniprot id: A0A3P8VNU2
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. cAMP subfamily.

244447:LOC103392360
gene id: 244447:LOC103392360
uniprot id: A0A3P8WFU3
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

244447:LOC103387612
gene id: 244447:LOC103387612
uniprot id: A0A3P8W4L9
names: Subcellular Location Annotation
messages: Lysosome membrane
messages: Membrane

244447:LOC103396641
gene id: 244447:LOC103396641
uniprot id: A0A3P8X094
names: Function
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

244447:usp33
gene id: 244447:usp33
uniprot id: A0A3P8X147
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C19 family. USP20/USP33 subfamily.
messages: centrosome
messages: perinuclear region

244447:LOC103396137
gene id: 244447:LOC103396137
uniprot id: A0A3P8WJD1
names: Subcellular Location Annotation
messages: Membrane

244447:LOC103386049
gene id: 244447:LOC103386049
uniprot id: A0A3P8V0P2
names: Similarity
messages: Belongs to the cytochrome P450 family.

244447:actr5
gene id: 244447:actr5
uniprot id: A0A3P8WTG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the actin family. ARP5 subfamily.
messages: Nucleus

244447:LOC103390119
gene id: 244447:LOC103390119
uniprot id: A0A3P8WDV5
names: Similarity
messages: Belongs to the WD repeat coronin family.

244447:LOC103377626
gene id: 244447:LOC103377626
uniprot id: A0A3P8ULX1
names: Similarity
messages: Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family.

244447:LOC103382755
gene id: 244447:LOC103382755
uniprot id: A0A3P8VDY4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIB subfamily.
messages: Catalyzes the hydrolysis of ATP coupled with the transport of calcium.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

244447:hddc2
gene id: 244447:hddc2
uniprot id: A0A3P8WYB8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HDDC2 family.
messages: Catalyzes the dephosphorylation of the nucleoside 5'-monophosphates deoxyadenosine monophosphate (dAMP), deoxycytidine monophosphate (dCMP), deoxyguanosine monophosphate (dGMP) and deoxythymidine monophosphate (dTMP).
messages: Homodimer.

244447:LOC103377199
gene id: 244447:LOC103377199
uniprot id: A0A3P8WEC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AB hydrolase superfamily. Lipase family.
messages: Secreted

244447:LOC103382985
gene id: 244447:LOC103382985
uniprot id: A0A3P8UIN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM54 family.
messages: Membrane

244447:LOC103378001
gene id: 244447:LOC103378001
uniprot id: A0A3P8V9U3
uniprot id: A0A3P8VDD5
uniprot id: A0A3P8VFL4
names: Subcellular Location Annotation
messages: extracellular matrix

244447:katnb1
gene id: 244447:katnb1
uniprot id: A0A3P8WV58
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat KATNB1 family.
messages: Cytoplasm
messages: Interacts with KATNA1. This interaction enhances the microtubule binding and severing activity of KATNA1 and also targets this activity to the centrosome.
messages: Participates in a complex which severs microtubules in an ATP-dependent manner. May act to target the enzymatic subunit of this complex to sites of action such as the centrosome. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation.
messages: centrosome
messages: cytoskeleton
messages: spindle
messages: spindle pole

244447:dusp8
gene id: 244447:dusp8
uniprot id: A0A3P8VI25
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.

244447:suds3
gene id: 244447:suds3
uniprot id: A0A3P8X1G9
names: Subcellular Location Annotation
messages: Nucleus

244447:gdf10
gene id: 244447:gdf10
uniprot id: A0A3P8X3W8
names: Similarity
messages: Belongs to the TGF-beta family.

244447:LOC103390799
gene id: 244447:LOC103390799
uniprot id: A0A3P8V045
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COE family.
messages: Nucleus

244447:LOC103389731
gene id: 244447:LOC103389731
uniprot id: A0A3P8W023
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel CLIC family.
messages: Cytoplasm
messages: Members of this family may change from a globular, soluble state to a state where the N-terminal domain is inserted into the membrane and functions as chloride channel. A conformation change of the N-terminal domain is thought to expose hydrophobic surfaces that trigger membrane insertion.
messages: Membrane

244447:mapre1
gene id: 244447:mapre1
uniprot id: S5M0P1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAPRE family.
messages: centrosome
messages: spindle pole

244447:LOC107988050
gene id: 244447:LOC107988050
uniprot id: C4PJT0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta-2-microglobulin family.
messages: Secreted

244447:LOC103391410
gene id: 244447:LOC103391410
uniprot id: A0A3P8WUJ9
names: Subcellular Location Annotation
messages: Membrane

244447:pxmp2
gene id: 244447:pxmp2
uniprot id: A0A3P8VI32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxisomal membrane protein PXMP2/4 family.
messages: Membrane

244447:LOC103389572
gene id: 244447:LOC103389572
uniprot id: A0A3P8V914
names: Similarity
messages: Belongs to the dynein light chain Tctex-type family.

244447:shc1
gene id: 244447:shc1
uniprot id: A0A3P8UMZ4
names: Subcellular Location Annotation
messages: Cytoplasm

244447:LOC103383721
gene id: 244447:LOC103383721
uniprot id: F8TE40
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the intercrine alpha (chemokine CxC) family.
messages: Homodimer.
messages: Secreted

244447:pik3c2a
gene id: 244447:pik3c2a
uniprot id: A0A3P8UG65
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.

244447:mycl
gene id: 244447:mycl
uniprot id: A0A3P8VKN5
names: Subcellular Location Annotation
names: Subunit
messages: Efficient DNA binding requires dimerization with another bHLH protein. Binds DNA as a heterodimer with MAX.
messages: Nucleus

244447:p2ry8
gene id: 244447:p2ry8
uniprot id: A0A3P8V483
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

244447:sox21
gene id: 244447:sox21
uniprot id: A0A3P8V1N8
names: Subcellular Location Annotation
messages: Nucleus

244447:LOC103383259
gene id: 244447:LOC103383259
uniprot id: A0A3P8X5A5
names: Similarity
messages: Belongs to the HEBP family.

244447:LOC103381979
gene id: 244447:LOC103381979
uniprot id: A0A3P8WX70
names: Similarity
messages: Belongs to the class I fructose-bisphosphate aldolase family.

244447:LOC103389570
gene id: 244447:LOC103389570
uniprot id: A0A3P8V312
uniprot id: A0A3P8V701
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

244447:prkcd
gene id: 244447:prkcd
uniprot id: A0A3P8UWZ3
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
messages: Calcium-independent, phospholipid- and diacylglycerol (DAG)-dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti-apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression.
messages: Cytoplasm
messages: Interacts with PDPK1 (via N-terminal region), RAD9A, CDCP1, MUC1 and VASP.
messages: Novel PKCs (PRKCD, PRKCE, PRKCH and PRKCQ) are calcium-insensitive, but activated by diacylglycerol (DAG) and phosphatidylserine.
messages: Nucleus
messages: perinuclear region

244447:tsen54
gene id: 244447:tsen54
uniprot id: A0A3P8WZ68
names: Similarity
messages: Belongs to the SEN54 family.

244447:prdm10
gene id: 244447:prdm10
uniprot id: A0A3P8V8Q9
names: Function
names: Subcellular Location Annotation
messages: May be involved in transcriptional regulation.
messages: Nucleus

244447:fam160b1
gene id: 244447:fam160b1
uniprot id: A0A3P8WAS0
names: Similarity
messages: Belongs to the FHIP family.

244447:LOC103377283
gene id: 244447:LOC103377283
uniprot id: A0A3P8WP12
names: Similarity
messages: Belongs to the cytochrome b5 family.

244447:ppp2r2d
gene id: 244447:ppp2r2d
uniprot id: A0A3P8WAB2
names: Similarity
messages: Belongs to the phosphatase 2A regulatory subunit B family.

244447:ptpn11
gene id: 244447:ptpn11
uniprot id: A0A3P8VXI6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class 2 subfamily.
messages: Cytoplasm

244447:dnpep
gene id: 244447:dnpep
uniprot id: A0A3P8UYC1
uniprot id: A0A3P8V4U1
names: Similarity
names: Subunit
messages: Belongs to the peptidase M18 family.
messages: Tetrahedron-shaped homododecamer built from six homodimers.

244447:celf4
gene id: 244447:celf4
uniprot id: A0A3P8V9A0
uniprot id: A0A3P8VCU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CELF/BRUNOL family.
messages: Cytoplasm
messages: Nucleus

244447:LOC103395884
gene id: 244447:LOC103395884
uniprot id: A0A3P8VU70
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

244447:sec13
gene id: 244447:sec13
uniprot id: A0A3P8X120
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat SEC13 family.
messages: Lysosome membrane
messages: nuclear pore complex

244447:LOC103392791
gene id: 244447:LOC103392791
uniprot id: A0A3P8VSM1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tweety family.
messages: Cell membrane
messages: Membrane
messages: Probable chloride channel.

244447:prph2
gene id: 244447:prph2
uniprot id: A0A3P8W683
names: Similarity
messages: Belongs to the PRPH2/ROM1 family.

244447:sart1
gene id: 244447:sart1
uniprot id: A0A3P8URW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNU66/SART1 family.
messages: Nucleus

244447:LOC103391968
gene id: 244447:LOC103391968
uniprot id: A0A3P8VFB0
names: Similarity
messages: Belongs to the interleukin-1 receptor family.

244447:foxk1
gene id: 244447:foxk1
uniprot id: A0A3P8UST7
names: Subcellular Location Annotation
messages: Nucleus

244447:rars
gene id: 244447:rars
uniprot id: A0A3P8X2T5
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

244447:LOC103393985
gene id: 244447:LOC103393985
uniprot id: A0A3P8VSU7
names: Similarity
messages: Belongs to the apolipoprotein A1/A4/E family.

244447:LOC103396287
gene id: 244447:LOC103396287
uniprot id: A0A3P8VRF0
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

244447:LOC103392198
gene id: 244447:LOC103392198
uniprot id: A0A3P8VXV1
names: Similarity
messages: Belongs to the glycosyl hydrolase 35 family.

244447:LOC103380810
gene id: 244447:LOC103380810
uniprot id: A0A3P8WZ10
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TGF-beta family.
messages: Homodimer; disulfide-linked.
messages: Transforming growth factor beta-3 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-3 (TGF-beta-3) chains, which constitute the regulatory and active subunit of TGF-beta-3, respectively.
messages: extracellular matrix

244447:ero1b
gene id: 244447:ero1b
uniprot id: A0A3P8UGV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EROs family.
messages: Endoplasmic reticulum membrane

244447:LOC103390452
gene id: 244447:LOC103390452
uniprot id: A0A3P8UKC5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaves the gamma-glutamyl peptide bond of glutathione and glutathione conjugates.
messages: Membrane

244447:tdrd3
gene id: 244447:tdrd3
uniprot id: A0A3P8UCL3
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus
messages: Scaffolding protein that specifically recognizes and binds dimethylarginine-containing proteins. In nucleus, acts as a coactivator: recognizes and binds asymmetric dimethylation on the core histone tails associated with transcriptional activation (H3R17me2a and H4R3me2a) and recruits proteins at these arginine-methylated loci. In cytoplasm, may play a role in the assembly and/or disassembly of mRNA stress granules and in the regulation of translation of target mRNAs by binding Arg/Gly-rich motifs (GAR) in dimethylarginine-containing proteins.

244447:ncbp3
gene id: 244447:ncbp3
uniprot id: A0A3P8V9L9
names: Similarity
messages: Belongs to the NCBP3 family.

244447:LOC103385300
gene id: 244447:LOC103385300
uniprot id: A0A3P8WPH0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.

244447:LOC103382257
gene id: 244447:LOC103382257
uniprot id: A0A3P8UKC9
names: Cofactor
names: Similarity
messages: Belongs to the arginase family.
messages: Binds 2 manganese ions per subunit.

244447:LOC103389296
gene id: 244447:LOC103389296
uniprot id: A0A3P8UHE2
uniprot id: A0A3P8UJ03
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.

244447:pfn2
gene id: 244447:pfn2
uniprot id: A0A3P8WC77
names: Function
names: Similarity
messages: Belongs to the profilin family.
messages: Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG.

244447:c3h3orf58
gene id: 244447:c3h3orf58
uniprot id: A0A3P8WB04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DIPK family.
messages: Secreted

244447:gal
gene id: 244447:gal
uniprot id: A0A3P8UHY0
uniprot id: A0A3P8UJG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the galanin family.
messages: Secreted

244447:cdk9
gene id: 244447:cdk9
uniprot id: A0A3P8VQ59
names: Similarity
messages: Belongs to the protein kinase superfamily.

244447:ptges2
gene id: 244447:ptges2
uniprot id: A0A3P8W8C6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GST superfamily.
messages: Membrane

244447:LOC103387225
gene id: 244447:LOC103387225
uniprot id: A0A3P8V4G8
names: Similarity
messages: Belongs to the alpha-ketoglutarate dehydrogenase family.

244447:sqle
gene id: 244447:sqle
uniprot id: A0A3P8VU81
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the squalene monooxygenase family.
messages: Catalyzes the stereospecific oxidation of squalene to (S)-2,3-epoxysqualene, and is considered to be a rate-limiting enzyme in steroid biosynthesis.
messages: Endoplasmic reticulum membrane

244447:elac2
gene id: 244447:elac2
uniprot id: A0A3P8X368
names: Similarity
messages: Belongs to the RNase Z family.

244447:LOC103381489
gene id: 244447:LOC103381489
uniprot id: A0A3P8VTB5
names: Subcellular Location Annotation
messages: Membrane
messages: cytoskeleton

244447:hspb6
gene id: 244447:hspb6
uniprot id: A0A3P8V2D9
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

244447:LOC103394693
gene id: 244447:LOC103394693
uniprot id: A0A3P8VKZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neurexophilin family.
messages: May be signaling molecules that resemble neuropeptides.
messages: Secreted

244447:efemp2
gene id: 244447:efemp2
uniprot id: A0A3P8V4Z4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

244447:LOC103392672
gene id: 244447:LOC103392672
uniprot id: A0A3P8X3N1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sesquipedalian family.
messages: Early endosome
messages: Plays a role in endocytic trafficking. Required for receptor recycling from endosomes, both to the trans-Golgi network and the plasma membrane.
messages: Recycling endosome
messages: clathrin-coated vesicle
messages: trans-Golgi network

244447:LOC103379030
gene id: 244447:LOC103379030
uniprot id: A0A3P8VFI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

244447:LOC103389255
gene id: 244447:LOC103389255
uniprot id: A0A3P8UY62
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane

244447:LOC103397141
gene id: 244447:LOC103397141
uniprot id: A0A3P8W3Y3
names: Similarity
messages: Belongs to the nucleosome assembly protein (NAP) family.

244447:LOC103378612
gene id: 244447:LOC103378612
uniprot id: A0A3P8ULV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vestigial family.
messages: Nucleus

244447:LOC103389210
gene id: 244447:LOC103389210
uniprot id: A0A3P8WR59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POU transcription factor family.
messages: Nucleus

244447:LOC103391206
gene id: 244447:LOC103391206
uniprot id: A0A3P8W9Q0
names: Similarity
messages: Belongs to the UPF0461 family.

244447:LOC103397598
gene id: 244447:LOC103397598
uniprot id: A0A3P8WYH2
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the prostaglandin G/H synthase family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

244447:arl5b
gene id: 244447:arl5b
uniprot id: A0A3P8UBX4
names: Similarity
messages: Belongs to the small GTPase superfamily. Arf family.

244447:satb2
gene id: 244447:satb2
uniprot id: A0A3P8UW68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CUT homeobox family.
messages: Nucleus

244447:sfrp5
gene id: 244447:sfrp5
uniprot id: A0A3P8VCF4
names: Caution
names: Similarity
messages: Belongs to the secreted frizzled-related protein (sFRP) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

244447:pgap3
gene id: 244447:pgap3
uniprot id: A0A3P8VMM7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PGAP3 family.
messages: Golgi apparatus membrane
messages: Involved in the lipid remodeling steps of GPI-anchor maturation.
messages: Membrane

244447:pfdn4
gene id: 244447:pfdn4
uniprot id: A0A3P8WAA8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prefoldin subunit beta family.
messages: Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins.
messages: Heterohexamer of two PFD-alpha type and four PFD-beta type subunits.

244447:LOC103394797
gene id: 244447:LOC103394797
uniprot id: A0A3P8VW89
names: Function
names: Similarity
messages: Belongs to the serpin family.
messages: Binds specifically to collagen. Could be involved as a chaperone in the biosynthetic pathway of collagen.

244447:tpra1
gene id: 244447:tpra1
uniprot id: A0A3P8V4R4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0359 family.
messages: Membrane

244447:prickle2
gene id: 244447:prickle2
uniprot id: A0A3P8V3R0
names: Similarity
messages: Belongs to the prickle / espinas / testin family.

244447:LOC103387240
gene id: 244447:LOC103387240
uniprot id: A0A3P8V342
names: Similarity
messages: Belongs to the small GTPase superfamily. Arf family.
messages: Belongs to the small GTPase superfamily. SAR1 family.

244447:LOC103378761
gene id: 244447:LOC103378761
uniprot id: A0A3P8UWB8
names: Similarity
messages: Belongs to the actin family.

244447:LOC103389409
gene id: 244447:LOC103389409
uniprot id: A0A3P8USG2
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

244447:LOC103377307
gene id: 244447:LOC103377307
uniprot id: A0A3P8WZB6
names: Domain
names: Similarity
messages: A pair of annexin repeats may form one binding site for calcium and phospholipid.
messages: Belongs to the annexin family.

244447:LOC103396448
gene id: 244447:LOC103396448
uniprot id: A0A3P8W487
names: Similarity
messages: Belongs to the RRM HNRPC family. RALY subfamily.

244447:scrn3
gene id: 244447:scrn3
uniprot id: A0A3P8UZU9
names: Similarity
messages: Belongs to the peptidase C69 family. Secernin subfamily.

244447:LOC103396127
gene id: 244447:LOC103396127
uniprot id: A0A3P8WKD4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide-sugar transporter family. SLC35A subfamily.
messages: Membrane

244447:LOC103389160
gene id: 244447:LOC103389160
uniprot id: A0A3P8WUQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tropomyosin family.
messages: cytoskeleton

244447:lamtor2
gene id: 244447:lamtor2
uniprot id: A0A3P8VWI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GAMAD family.
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane

244447:LOC103386587
gene id: 244447:LOC103386587
uniprot id: A0A3P8UFK8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Interacts with MPDZ. Interacts with ARRB2.
messages: Membrane

244447:ift20
gene id: 244447:ift20
uniprot id: A0A3P8UVE4
names: Subcellular Location Annotation
messages: centriole
messages: cilium
messages: cis-Golgi network

244447:cse1l
gene id: 244447:cse1l
uniprot id: A0A3P8UPK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XPO2/CSE1 family.
messages: Cytoplasm

244447:asah1
gene id: 244447:asah1
uniprot id: A0A3P8WHL3
names: Similarity
messages: Belongs to the acid ceramidase family.

244447:mtx3
gene id: 244447:mtx3
uniprot id: A0A3P8WEJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metaxin family.
messages: Membrane
messages: Mitochondrion outer membrane

244447:rps2
gene id: 244447:rps2
uniprot id: A0A3P8WCZ7
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel. Plays a role in the assembly and function of the 40S ribosomal subunit. Mutations in this protein affects the control of translational fidelity. Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly.

244447:slc7a4
gene id: 244447:slc7a4
uniprot id: A0A3P8WS50
names: Subcellular Location Annotation
messages: Membrane

244447:cdkn1b
gene id: 244447:cdkn1b
uniprot id: A0A3P8VJ99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDI family.
messages: Cytoplasm
messages: Endosome
messages: Nucleus

244447:LOC103384817
gene id: 244447:LOC103384817
uniprot id: A0A3P8UYX1
uniprot id: A0A3P8V0D6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

244447:snrnp200
gene id: 244447:snrnp200
uniprot id: A0A3P8WH23
names: Similarity
messages: Belongs to the helicase family. SKI2 subfamily.

244447:agtpbp1
gene id: 244447:agtpbp1
uniprot id: A0A3P8VZ54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M14 family.
messages: cytosol

244447:LOC103395929
gene id: 244447:LOC103395929
uniprot id: A0A3P8W8W9
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

244447:ube4a
gene id: 244447:ube4a
uniprot id: A0A3P8VLU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ubiquitin conjugation factor E4 family.
messages: Cytoplasm

244447:LOC103392583
gene id: 244447:LOC103392583
uniprot id: A0A3P8X1J5
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family. PDE4 subfamily.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

244447:mdh2
gene id: 244447:mdh2
uniprot id: A0A3P8VIR3
names: Similarity
names: Subunit
messages: Belongs to the LDH/MDH superfamily. MDH type 1 family.
messages: Homodimer.

244447:LOC103386419
gene id: 244447:LOC103386419
uniprot id: A0A3P8W1L1
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

244447:LOC103393154
gene id: 244447:LOC103393154
uniprot id: A0A3P8WI31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the actinoporin family. Sea anemone subfamily.
messages: Cell membrane
messages: Membrane
messages: Nematocyst
messages: Target cell membrane

244447:LOC103392857
gene id: 244447:LOC103392857
uniprot id: A0A3P8VW07
names: Subcellular Location Annotation
messages: Nucleus

244447:anapc15
gene id: 244447:anapc15
uniprot id: A0A3P8WSY0
names: Similarity
messages: Belongs to the APC15 family.

244447:LOC103396892
gene id: 244447:LOC103396892
uniprot id: A0A1D8QQG2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

244447:trmt1
gene id: 244447:trmt1
uniprot id: A0A3P8UP50
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family.

244447:atp7a
gene id: 244447:atp7a
uniprot id: A0A3P8WHI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Membrane
messages: trans-Golgi network membrane

244447:LOC103397455
gene id: 244447:LOC103397455
uniprot id: A0A3P8VMJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Elbow/Noc family.
messages: Nucleus

244447:irf9
gene id: 244447:irf9
uniprot id: A0A3P8WBU0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IRF family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

244447:cdip1
gene id: 244447:cdip1
uniprot id: A0A3P8VUM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDIP1/LITAF family.
messages: Lysosome membrane
messages: Membrane

244447:pym1
gene id: 244447:pym1
uniprot id: A0A3P8X3U1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pym family.
messages: Cytoplasm
messages: Interacts (via N-terminus) with magoh and rbm8a; the interaction is direct. Associates (eIF2A-like region) with the 40S ribosomal subunit and the 48S preinitiation complex.

244447:LOC103393642
gene id: 244447:LOC103393642
uniprot id: G0ZAK7
names: Function
names: Similarity
messages: Belongs to the ferritin family.
messages: Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.

244447:plag1
gene id: 244447:plag1
uniprot id: A0A3P8VNG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the krueppel C2H2-type zinc-finger protein family.
messages: Nucleus

244447:gabrg1
gene id: 244447:gabrg1
uniprot id: A0A3P8UZ50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

244447:LOC103376912
gene id: 244447:LOC103376912
uniprot id: A0A3P8VGI8
uniprot id: A0A3P8VLU3
names: Similarity
messages: Belongs to the beta-catenin family.

244447:LOC103386316
gene id: 244447:LOC103386316
uniprot id: A0A3P8VLX6
names: Similarity
messages: Belongs to the FAM83 family.

244447:LOC103377437
gene id: 244447:LOC103377437
uniprot id: A0A3P8UD33
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane
messages: Membrane

244447:LOC103396647
gene id: 244447:LOC103396647
uniprot id: A0A3P8X099
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tissue factor family.
messages: Initiates blood coagulation by forming a complex with circulating factor VII or VIIa. The [TF:VIIa] complex activates factors IX or X by specific limited proteolysis. TF plays a role in normal hemostasis by initiating the cell-surface assembly and propagation of the coagulation protease cascade.
messages: Interacts with HSPE; the interaction, inhibited by heparin, promotes the generation of activated factor X and activates coagulation in the presence of activated factor VII.

244447:LOC103385007
gene id: 244447:LOC103385007
uniprot id: A0A3P8V4K2
names: Caution
names: Similarity
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

244447:LOC103382128
gene id: 244447:LOC103382128
uniprot id: A0A3P8WYD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATR family.
messages: Membrane

244447:LOC103378259
gene id: 244447:LOC103378259
uniprot id: A0A3P8W9D1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ITPK1 family.
messages: Binds 2 magnesium ions per subunit.
messages: Kinase that can phosphorylate various inositol polyphosphate such as Ins(3,4,5,6)P4 or Ins(1,3,4)P3.
messages: Monomer.

244447:fan1
gene id: 244447:fan1
uniprot id: A0A3P8W105
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAN1 family.
messages: Nuclease required for the repair of DNA interstrand cross-links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions.
messages: Nucleus

244447:aldh3b1
gene id: 244447:aldh3b1
uniprot id: A0A3P8WAB9
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

244447:LOC103382271
gene id: 244447:LOC103382271
uniprot id: A0A3P8UJQ9
names: Similarity
messages: Belongs to the BTG family.

244447:LOC112486237
gene id: 244447:LOC112486237
uniprot id: A0A3P8V7J5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family. Beta3-Gal-T subfamily.
messages: Membrane

244447:LOC103383794
gene id: 244447:LOC103383794
uniprot id: A0A3P8V506
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family.
messages: Membrane

244447:tasp1
gene id: 244447:tasp1
uniprot id: A0A3P8V5R1
names: Similarity
messages: Belongs to the Ntn-hydrolase family.

244447:acmsd
gene id: 244447:acmsd
uniprot id: A0A3P8WY62
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. ACMSD family.
messages: Converts alpha-amino-beta-carboxymuconate-epsilon-semialdehyde (ACMS) to alpha-aminomuconate semialdehyde (AMS). ACMS can be converted non-enzymatically to quinolate (QA), a key precursor of NAD, and a potent endogenous excitotoxin of neuronal cells which is implicated in the pathogenesis of various neurodegenerative disorders. In the presence of ACMSD, ACMS is converted to AMS, a benign catabolite. ACMSD ultimately controls the metabolic fate of tryptophan catabolism along the kynurenine pathway.
messages: Monomer.

244447:LOC103396460
gene id: 244447:LOC103396460
uniprot id: A0A3P8W8C7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. Insulin receptor subfamily.
messages: Cell membrane
messages: Membrane

244447:LOC103393172
gene id: 244447:LOC103393172
uniprot id: A0A3P8WJT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transcription factor STAT family.
messages: Cytoplasm
messages: Nucleus

244447:scoc
gene id: 244447:scoc
uniprot id: A0A3P8W8L1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCOC family.
messages: Positive regulator of amino acid starvation-induced autophagy.
messages: trans-Golgi network

244447:adrb1
gene id: 244447:adrb1
uniprot id: A0A3P8V6N3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

244447:naaa
gene id: 244447:naaa
uniprot id: A0A3P8W460
names: Similarity
messages: Belongs to the acid ceramidase family.

244447:edc3
gene id: 244447:edc3
uniprot id: A0A3P8W1E3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EDC3 family.
messages: P-body

244447:LOC103383895
gene id: 244447:LOC103383895
uniprot id: A0A3P8VJK8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UDPGP type 1 family.
messages: Homooctamer.
messages: UTP--glucose-1-phosphate uridylyltransferase catalyzing the conversion of glucose-1-phosphate into UDP-glucose, a crucial precursor for the production of glycogen.

244447:penk
gene id: 244447:penk
uniprot id: A0A3P8X1X3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the opioid neuropeptide precursor family.
messages: Secreted

244447:sec61a1
gene id: 244447:sec61a1
uniprot id: A0A3P8V1J8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Endoplasmic reticulum membrane
messages: Heterotrimeric complex composed of SEC61-alpha, SEC61-beta and SEC61-gamma.
messages: Membrane
messages: Plays a crucial role in the insertion of secretory and membrane polypeptides into the ER. Required for assembly of membrane and secretory proteins. Tightly associated with membrane-bound ribosomes, either directly or through adapter proteins (By similarity). Plays a role in pronephric kidney tubule development.

244447:spx
gene id: 244447:spx
uniprot id: A0A344X2U7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the spexin family.
messages: Secreted

244447:LOC103378986
gene id: 244447:LOC103378986
uniprot id: A0A3P8V979
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

244447:LOC103391285
gene id: 244447:LOC103391285
uniprot id: A0A3P8WMN3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glypican family.
messages: Cell membrane
messages: Cell surface proteoglycan that bears heparan sulfate.

244447:tmem87b
gene id: 244447:tmem87b
uniprot id: A0A3P8VXQ8
names: Subcellular Location Annotation
messages: Membrane

244447:hars
gene id: 244447:hars
uniprot id: A0A3P8UR89
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.

244447:LOC103389486
gene id: 244447:LOC103389486
uniprot id: A0A3P8V2T0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sphingomyelin synthase family.
messages: Membrane

244447:gart
gene id: 244447:gart
uniprot id: A0A3P8V103
names: Similarity
messages: In the C-terminal section; belongs to the GART family.
messages: In the N-terminal section; belongs to the GARS family.
messages: In the central section; belongs to the AIR synthase family.

244447:LOC103391596
gene id: 244447:LOC103391596
uniprot id: A0A3P8W4Y3
names: Similarity
messages: Belongs to the BolA/IbaG family.

244447:clcn7
gene id: 244447:clcn7
uniprot id: A0A3P8WQG3
uniprot id: A0A3P8WTZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel (TC 2.A.49) family.
messages: Membrane

244447:LOC103389868
gene id: 244447:LOC103389868
uniprot id: A0A3P8VU95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Ras family.
messages: Endosome membrane
messages: Recycling endosome membrane

244447:tmco3
gene id: 244447:tmco3
uniprot id: A0A3P8V6A1
uniprot id: A0A3P8VA05
names: Subcellular Location Annotation
messages: Membrane

244447:perp
gene id: 244447:perp
uniprot id: A0A3P8UGV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM47 family.
messages: Membrane

244447:LOC103384078
gene id: 244447:LOC103384078
uniprot id: A0A3P8VWR6
names: Similarity
messages: Belongs to the aldolase class II family. Adducin subfamily.

244447:upf3b
gene id: 244447:upf3b
uniprot id: A0A3P8UIR8
names: Similarity
messages: Belongs to the RENT3 family.

244447:mettl6
gene id: 244447:mettl6
uniprot id: A0A3P8VMB5
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. METL family.
messages: S-adenosyl-L-methionine-dependent methyltransferase.

244447:LOC103393456
gene id: 244447:LOC103393456
uniprot id: A0A3P8VQ58
names: Similarity
messages: Belongs to the SH2B adapter family.

244447:LOC103392716
gene id: 244447:LOC103392716
uniprot id: A0A3P8VMK7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
messages: cytoskeleton

244447:cd248
gene id: 244447:cd248
uniprot id: A0A3P8WZL3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

244447:LOC103380097
gene id: 244447:LOC103380097
uniprot id: A0A3P8V5F4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Membrane

244447:sys1
gene id: 244447:sys1
uniprot id: A0A3P8US04
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SYS1 family.
messages: Golgi apparatus membrane
messages: Interacts with ARFRP1.
messages: Involved in protein trafficking. May serve as a receptor for ARFRP1.
messages: Membrane

244447:egfl6
gene id: 244447:egfl6
uniprot id: A0A3P8VN42
names: Caution
names: Similarity
messages: Belongs to the nephronectin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

244447:dgat2
gene id: 244447:dgat2
uniprot id: A0A3P8W1B9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the diacylglycerol acyltransferase family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

244447:LOC103389253
gene id: 244447:LOC103389253
uniprot id: A0A3P8UEL2
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

244447:dgkq
gene id: 244447:dgkq
uniprot id: A0A3P8W084
names: Similarity
messages: Belongs to the eukaryotic diacylglycerol kinase family.

244447:cenpk
gene id: 244447:cenpk
uniprot id: A0A3P8WF96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CENP-K/MCM22 family.
messages: Nucleus
messages: centromere

244447:spc25
gene id: 244447:spc25
uniprot id: A0A3P8VY10
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.
messages: Belongs to the SPC25 family.
messages: Component of the NDC80 complex.
messages: Nucleus
messages: kinetochore

244447:rpf2
gene id: 244447:rpf2
uniprot id: A0A3P8WDW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RPF2 family.
messages: nucleolus

244447:LOC103397037
gene id: 244447:LOC103397037
uniprot id: A0A3P8VUB3
names: Similarity
messages: Belongs to the PP2C family.

244447:slc6a19
gene id: 244447:slc6a19
uniprot id: A0A3P8VQM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

244447:LOC103397124
gene id: 244447:LOC103397124
uniprot id: A0A3P8VZP8
names: Similarity
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. RAF subfamily.

244447:LOC103386647
gene id: 244447:LOC103386647
uniprot id: A0A3P8WNR0
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL22 family.

244447:drd2
gene id: 244447:drd2
uniprot id: A0A3P8WK43
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

244447:LOC103394990
gene id: 244447:LOC103394990
uniprot id: A0A3P8WN01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. SLC8 subfamily.
messages: Cell membrane
messages: Membrane

244447:LOC103386184
gene id: 244447:LOC103386184
uniprot id: A0A3P8V4L4
names: Similarity
messages: Belongs to the TAFA family.

244447:lrrc8a
gene id: 244447:lrrc8a
uniprot id: A0A3P8WBK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LRRC8 family.
messages: Cell membrane
messages: Membrane

244447:aldh18a1
gene id: 244447:aldh18a1
uniprot id: A0A3P8W281
names: Similarity
messages: In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family.
messages: In the N-terminal section; belongs to the glutamate 5-kinase family.

244447:LOC103390317
gene id: 244447:LOC103390317
uniprot id: A0A3P8WWH5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mediates sulfate transport with high affinity. Mediates oxalate transport. Mediates bicarbonate transport. Does not accept succinate as cosubstrate.
messages: Membrane

244447:LOC103378863
gene id: 244447:LOC103378863
uniprot id: A0A3P8V528
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

244447:LOC103396400
gene id: 244447:LOC103396400
uniprot id: A0A3P8VYU7
names: Similarity
messages: Belongs to the EF-1-beta/EF-1-delta family.

244447:nkx6-2
gene id: 244447:nkx6-2
uniprot id: A0A3P8VPV4
names: Subcellular Location Annotation
messages: Nucleus

244447:neto1
gene id: 244447:neto1
uniprot id: A0A3P8VPH5
uniprot id: A0A3P8VSC9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

244447:march4
gene id: 244447:march4
uniprot id: A0A3P8VWJ6
names: Subcellular Location Annotation
messages: Membrane

244447:uba2
gene id: 244447:uba2
uniprot id: A0A3P8WB31
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ubiquitin-activating E1 family.
messages: Heterodimer of SAE1 and UBA2/SAE2. The heterodimer corresponds to the two domains that are encoded on a single polypeptide chain in ubiquitin-activating enzyme E1. Interacts with UBE2I.
messages: Nucleus
messages: The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2.

244447:akap12
gene id: 244447:akap12
uniprot id: A0A3P8VBZ8
names: Subcellular Location Annotation
messages: Membrane

244447:parp11
gene id: 244447:parp11
uniprot id: A0A3P8VK18
names: Similarity
messages: Belongs to the ARTD/PARP family.

244447:LOC103392954
gene id: 244447:LOC103392954
uniprot id: A0A3P8VZ23
names: Similarity
messages: Belongs to the BTG family.

244447:slc35a5
gene id: 244447:slc35a5
uniprot id: A0A3P8URI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide-sugar transporter family. SLC35A subfamily.
messages: Membrane

244447:fam120b
gene id: 244447:fam120b
uniprot id: A0A3P8W6G0
names: Similarity
messages: Belongs to the constitutive coactivator of PPAR-gamma family.

244447:LOC103394371
gene id: 244447:LOC103394371
uniprot id: A0A3P8WEF7
names: Similarity
messages: Belongs to the GIPC family.

244447:tsnare1
gene id: 244447:tsnare1
uniprot id: A0A3P8W1A5
names: Similarity
messages: Belongs to the syntaxin family.

244447:LOC103394265
gene id: 244447:LOC103394265
uniprot id: A0A3P8WH54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily.
messages: Membrane
messages: synaptic vesicle membrane

244447:LOC103393285
gene id: 244447:LOC103393285
uniprot id: A0A3P8V5D8
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

244447:pdss2
gene id: 244447:pdss2
uniprot id: A0A3P8WEG0
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

244447:tmem145
gene id: 244447:tmem145
uniprot id: A0A3P8VUX9
names: Subcellular Location Annotation
messages: Membrane

244447:LOC103395881
gene id: 244447:LOC103395881
uniprot id: A0A3P8W0S3
names: Similarity
messages: Belongs to the TGF-beta family.

244447:laptm4b
gene id: 244447:laptm4b
uniprot id: A0A3P8VJF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LAPTM4/LAPTM5 transporter family.
messages: Cell membrane
messages: Endomembrane system
messages: Endosome membrane
messages: Late endosome membrane
messages: Membrane
messages: multivesicular body lumen
messages: multivesicular body membrane

244447:plscr3
gene id: 244447:plscr3
uniprot id: A0A3P8UL37
names: Function
names: Similarity
messages: Belongs to the phospholipid scramblase family.
messages: May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane.

244447:LOC103389360
gene id: 244447:LOC103389360
uniprot id: A0A3P8URW9
names: Subcellular Location Annotation
messages: Cell membrane
messages: focal adhesion

244447:slc37a2
gene id: 244447:slc37a2
uniprot id: A0A3P8X1Z3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family.
messages: Membrane

244447:LOC103387523
gene id: 244447:LOC103387523
uniprot id: A0A3P8VSM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
messages: Membrane

244447:LOC103385763
gene id: 244447:LOC103385763
uniprot id: A0A3P8UJW9
names: Subcellular Location Annotation
messages: mitochondrion nucleoid

244447:cat
gene id: 244447:cat
uniprot id: A0A3P8UTB2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the catalase family.
messages: Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.
messages: Peroxisome

244447:comp
gene id: 244447:comp
uniprot id: A0A3P8WUA6
names: Caution
names: Similarity
messages: Belongs to the thrombospondin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

244447:LOC103392468
gene id: 244447:LOC103392468
uniprot id: A0A3P8WYK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

244447:sdhaf2
gene id: 244447:sdhaf2
uniprot id: A0A3P8UKS1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SDHAF2 family.
messages: Interacts with SDHA within the SDH catalytic dimer.
messages: Mitochondrion matrix
messages: Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SDHA of the SDH catalytic dimer.

244447:LOC103390852
gene id: 244447:LOC103390852
uniprot id: A0A3P8V2K0
names: Similarity
messages: Belongs to the peptidase S1B family.

244447:LOC103382047
gene id: 244447:LOC103382047
uniprot id: A0A3P8X3M9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Cytoplasm
messages: Homodimer and heterodimer with SSTR3 and SSTR5. Heterodimerization with SSTR3 inactivates SSTR3 receptor function. Heterodimerization with SSTR5 is enhanced by agonist stimulation of SSTR2 and increases SSTR2 cell growth inhibition activity. Following agonist stimulation, homodimers dissociate into monomers which is required for receptor internalization. Interacts with beta-arrestin; this interaction is necessary for receptor internalization and is destabilized by heterodimerization with SSTR5 which results in increased recycling of SSTR2 to the cell surface. Interacts (via C-terminus) with SHANK1 (via PDZ domain).
messages: Membrane
messages: Receptor for somatostatin-14 and -28. This receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase. In addition it stimulates phosphotyrosine phosphatase and PLC via pertussis toxin insensitive as well as sensitive G proteins. Inhibits calcium entry by suppressing voltage-dependent calcium channels. Acts as the functionally dominant somatostatin receptor in pancreatic alpha- and beta-cells where it mediates the inhibitory effect of somatostatin-14 on hormone secretion. Inhibits cell growth through enhancement of MAPK1 and MAPK2 phosphorylation and subsequent up-regulation of CDKN1B. Stimulates neuronal migration and axon outgrowth and may participate in neuron development and maturation during brain development. Mediates negative regulation of insulin receptor signaling through PTPN6. Inactivates SSTR3 receptor function following heterodimerization.

244447:grin2a
gene id: 244447:grin2a
uniprot id: A0A3P8WSH3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.
messages: Synaptic cell membrane

244447:ilf3
gene id: 244447:ilf3
uniprot id: A0A3P8WIT8
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

244447:chaf1b
gene id: 244447:chaf1b
uniprot id: A0A3P8VS32
names: Subcellular Location Annotation
messages: Nucleus

244447:adamts15
gene id: 244447:adamts15
uniprot id: A0A3P8V5K4
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

244447:LOC103397477
gene id: 244447:LOC103397477
uniprot id: A0A3P8VKA6
names: Similarity
messages: Belongs to the PPP phosphatase family.

244447:LOC103388774
gene id: 244447:LOC103388774
uniprot id: A0A3P8VWH3
names: Similarity
messages: Belongs to the FXYD family.

244447:LOC103392903
gene id: 244447:LOC103392903
uniprot id: A0A3P8W531
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
messages: Component of a calcium channel complex consisting of a pore-forming alpha subunit (CACNA1S) and the ancillary subunits CACNB1 or CACNB2, CACNG1 and CACNA2D1. The channel complex contains alpha, beta, gamma and delta subunits in a 1:1:1:1 ratio, i.e. it contains either CACNB1 or CACNB2.
messages: Membrane
messages: Regulatory subunit of the voltage-gated calcium channel that gives rise to L-type calcium currents in skeletal muscle. Regulates channel inactivation kinetics.
messages: sarcolemma

244447:bcl2
gene id: 244447:bcl2
uniprot id: A0A3P8WUE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Bcl-2 family.
messages: Cytoplasm
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Mitochondrion outer membrane
messages: Nucleus membrane

244447:ccdc47
gene id: 244447:ccdc47
uniprot id: A0A3P8X3M2
names: Subcellular Location Annotation
messages: Membrane
messages: Rough endoplasmic reticulum membrane

244447:LOC103380731
gene id: 244447:LOC103380731
uniprot id: A0A3P8WSM5
names: Similarity
messages: Belongs to the serpin family.

244447:LOC103387363
gene id: 244447:LOC103387363
uniprot id: A0A3P8VEQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.
messages: Cytoplasm
messages: Responds to activation by environmental stress and pro-inflammatory cytokines by phosphorylating a number of transcription factors, and thus regulates transcriptional activity.

244447:bicc1
gene id: 244447:bicc1
uniprot id: A0A3P8V162
names: Similarity
messages: Belongs to the BicC family.

244447:LOC103384245
gene id: 244447:LOC103384245
uniprot id: A0A3P8WBL1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family.
messages: Membrane

244447:wdpcp
gene id: 244447:wdpcp
uniprot id: A0A3P8UE12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat fritz family.
messages: Cell membrane
messages: Membrane
messages: cilium axoneme

244447:cog6
gene id: 244447:cog6
uniprot id: A0A3P8V8Q0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the COG6 family.
messages: Component of the conserved oligomeric Golgi complex which is composed of eight different subunits and is required for normal Golgi morphology and localization.
messages: Golgi apparatus membrane
messages: Membrane
messages: Required for normal Golgi function.

244447:lancl3
gene id: 244447:lancl3
uniprot id: A0A3P8UXZ4
names: Similarity
messages: Belongs to the LanC-like protein family.

244447:LOC103383512
gene id: 244447:LOC103383512
uniprot id: A0A3P8UTH6
names: Cofactor
names: Similarity
messages: Belongs to the AspA/AstE family. Aspartoacylase subfamily.
messages: Binds 1 zinc ion per subunit.

244447:LOC103387528
gene id: 244447:LOC103387528
uniprot id: A0A3P8VVM5
names: Subcellular Location Annotation
messages: Nucleus

244447:LOC103379054
gene id: 244447:LOC103379054
uniprot id: A0A3P8VJU8
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

244447:gosr2
gene id: 244447:gosr2
uniprot id: A0A3P8X2C4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GOSR2 family.
messages: Involved in transport of proteins from the cis/medial-Golgi to the trans-Golgi network.
messages: Membrane

244447:telo2
gene id: 244447:telo2
uniprot id: A0A3P8W0X6
names: Similarity
messages: Belongs to the TEL2 family.

244447:LOC103378138
gene id: 244447:LOC103378138
uniprot id: A0A3P8UTR2
uniprot id: A0A3P8UUZ9
names: Similarity
messages: Belongs to the phosphatase 2A regulatory subunit B56 family.

244447:LOC103391381
gene id: 244447:LOC103391381
uniprot id: A0A3P8X2C7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SCC3 family.
messages: Chromosome
messages: Component of cohesin complex, a complex required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate.
messages: Nucleus
messages: Part of the cohesin complex which is composed of a heterodimer between a SMC1 protein (SMC1A or SMC1B) and SMC3, which are attached via their hinge domain, and RAD21 which link them at their heads, and one STAG protein.
messages: centromere

244447:sostdc1
gene id: 244447:sostdc1
uniprot id: A0A3P8WDE6
names: Caution
names: Similarity
messages: Belongs to the sclerostin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

244447:naa10
gene id: 244447:naa10
uniprot id: A0A3P8UMT7
names: Similarity
messages: Belongs to the acetyltransferase family. ARD1 subfamily.

244447:LOC103396173
gene id: 244447:LOC103396173
uniprot id: A0A3P8WML3
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

244447:spon2
gene id: 244447:spon2
uniprot id: A0A3P8UTW2
names: Subcellular Location Annotation
messages: extracellular matrix

244447:LOC103387208
gene id: 244447:LOC103387208
uniprot id: A0A3P8UZE1
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

244447:sirt4
gene id: 244447:sirt4
uniprot id: A0A3P8UN66
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sirtuin family. Class II subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Mitochondrion matrix
messages: NAD-dependent protein deacylase. Catalyzes the NAD-dependent hydrolysis of acyl groups from lysine residues.

244447:emc2
gene id: 244447:emc2
uniprot id: A0A3P8VJB2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EMC2 family.
messages: Component of the ER membrane protein complex (EMC).
messages: Endoplasmic reticulum membrane
messages: Part of the endoplasmic reticulum membrane protein complex (EMC) that enables the energy-independent insertion into endoplasmic reticulum membranes of newly synthesized membrane proteins.

244447:LOC103377076
gene id: 244447:LOC103377076
uniprot id: A0A3P8W8Q4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the steroid 5-alpha reductase family.
messages: Endoplasmic reticulum membrane
messages: Membrane

244447:nkx2-8
gene id: 244447:nkx2-8
uniprot id: A0A3P8V9J5
names: Subcellular Location Annotation
messages: Nucleus

244447:wbp4
gene id: 244447:wbp4
uniprot id: A0A3P8V6Q6
names: Subcellular Location Annotation
messages: Nucleus

244447:sigirr
gene id: 244447:sigirr
uniprot id: A0A3P8V9I5
names: Similarity
messages: Belongs to the interleukin-1 receptor family.

244447:LOC103393706
gene id: 244447:LOC103393706
uniprot id: A0A3P8WCV4
names: Similarity
messages: Belongs to the importin alpha family.

244447:LOC103394408
gene id: 244447:LOC103394408
uniprot id: A0A3P8WQG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAR6 family.
messages: Cytoplasm
messages: tight junction

244447:mcm2
gene id: 244447:mcm2
uniprot id: A0A3P8X3U2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCM family.
messages: Nucleus

244447:anxa3
gene id: 244447:anxa3
uniprot id: A0A3P8UL42
names: Domain
names: Similarity
messages: A pair of annexin repeats may form one binding site for calcium and phospholipid.
messages: Belongs to the annexin family.

244447:cacng5
gene id: 244447:cacng5
uniprot id: A0A3P8VNN2
names: Similarity
messages: Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.

244447:LOC103384712
gene id: 244447:LOC103384712
uniprot id: A0A3P8UTU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Endoplasmic reticulum membrane
messages: Membrane

244447:sox14
gene id: 244447:sox14
uniprot id: A0A3P8VNC2
names: Subcellular Location Annotation
messages: Nucleus

244447:LOC103383650
gene id: 244447:LOC103383650
uniprot id: A0A3P8V2B2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

244447:LOC103385642
gene id: 244447:LOC103385642
uniprot id: A0A3P8X4N2
names: Subcellular Location Annotation
messages: Nucleus

244447:LOC103399916
gene id: 244447:LOC103399916
uniprot id: A0A3P8UU32
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

244447:LOC103380225
gene id: 244447:LOC103380225
uniprot id: A0A3P8VCX4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R-hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the second into a water molecule. Two electrons are provided by NADPH via a two-protein mitochondrial transfer system comprising flavoprotein FDXR (adrenodoxin/ferredoxin reductase) and nonheme iron-sulfur protein FDX1 or FDX2 (adrenodoxin/ferredoxin).
messages: Belongs to the cytochrome P450 family.
messages: Mitochondrion inner membrane

244447:psme1
gene id: 244447:psme1
uniprot id: A0A3P8VL44
names: Similarity
messages: Belongs to the PA28 family.

244447:LOC103398239
gene id: 244447:LOC103398239
uniprot id: A0A3P8W6X0
names: Caution
names: Cofactor
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

244447:LOC103382209
gene id: 244447:LOC103382209
uniprot id: A0A3P8UQ92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the actinoporin family. Sea anemone subfamily.
messages: Cell membrane
messages: Membrane
messages: Nematocyst
messages: Target cell membrane

244447:lsamp
gene id: 244447:lsamp
uniprot id: A0A3P8US24
names: Subcellular Location Annotation
messages: Membrane

244447:LOC103391399
gene id: 244447:LOC103391399
uniprot id: A0A3P8WUV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

244447:hook1
gene id: 244447:hook1
uniprot id: A0A3P8VG93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the hook family.
messages: cytoskeleton

244447:plpp4
gene id: 244447:plpp4
uniprot id: A0A3P8WSK8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Membrane

244447:LOC103379313
gene id: 244447:LOC103379313
uniprot id: A0A3P8VPL5
names: Caution
names: Similarity
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

244447:LOC103399906
gene id: 244447:LOC103399906
uniprot id: A0A3P8ULJ0
names: Subcellular Location Annotation
messages: extracellular space

244447:tm9sf3
gene id: 244447:tm9sf3
uniprot id: A0A3P8VQZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family.
messages: Membrane

244447:LOC103378895
gene id: 244447:LOC103378895
uniprot id: A0A3P8V2Q9
uniprot id: A0A3P8V8X5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glypican family.
messages: Cell membrane
messages: Cell surface proteoglycan that bears heparan sulfate.

244447:gemin2
gene id: 244447:gemin2
uniprot id: A0A3P8WKE3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the gemin-2 family.
messages: Cytoplasm
messages: Part of the core SMN complex.
messages: The SMN complex catalyzes the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome, and thereby plays an important role in the splicing of cellular pre-mRNAs.

244447:LOC103391287
gene id: 244447:LOC103391287
uniprot id: A0A3P8WGY7
names: Similarity
messages: Belongs to the DDIT4 family.

244447:LOC103377847
gene id: 244447:LOC103377847
uniprot id: A0A3P8V2B0
names: Similarity
messages: Belongs to the cytochrome P450 family.

244447:mrps18b
gene id: 244447:mrps18b
uniprot id: A0A3P8WR23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial ribosomal protein bS18 family. Mitochondrion-specific ribosomal protein mS40 subfamily.
messages: Mitochondrion

244447:kcnj2
gene id: 244447:kcnj2
uniprot id: A0A3P8UPZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family. KCNJ2 subfamily.
messages: Membrane

244447:nr2e1
gene id: 244447:nr2e1
uniprot id: A0A3P8WLA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

244447:LOC103382853
gene id: 244447:LOC103382853
uniprot id: A0A3P8VNQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptophysin/synaptobrevin family.
messages: Membrane

244447:LOC103383654
gene id: 244447:LOC103383654
uniprot id: A0A3P8UU41
names: Similarity
messages: Belongs to the CCDC149 family.

244447:slc45a4
gene id: 244447:slc45a4
uniprot id: A0A3P8WA01
names: Subcellular Location Annotation
messages: Membrane

244447:LOC103379943
gene id: 244447:LOC103379943
uniprot id: A0A3P8UNE3
names: Function
names: Similarity
messages: Belongs to the troponin T family.
messages: Troponin T is the tropomyosin-binding subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity.

244447:fam189a2
gene id: 244447:fam189a2
uniprot id: A0A3P8VER2
names: Similarity
messages: Belongs to the ENTREP family.

244447:bola1
gene id: 244447:bola1
uniprot id: A0A3P8W1H0
names: Similarity
messages: Belongs to the BolA/IbaG family.

244447:mastl
gene id: 244447:mastl
uniprot id: A0A3P8WS00
uniprot id: A0A3P8WXV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.
messages: Nucleus
messages: centrosome

244447:b4galt7
gene id: 244447:b4galt7
uniprot id: A0A3P8W2G7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 7 family.
messages: Golgi apparatus membrane
messages: Membrane
messages: Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids.

244447:LOC103382684
gene id: 244447:LOC103382684
uniprot id: A0A3P8V9A5
names: Similarity
messages: Belongs to the V-ATPase E subunit family.

244447:eif3d
gene id: 244447:eif3d
uniprot id: A0A3P8WX93
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit D family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M.
messages: Cytoplasm
messages: The RNA gate region regulates mRNA cap recognition to prevent promiscuous mRNA-binding before assembly of eif3d into the full eukaryotic translation initiation factor 3 (eIF-3) complex.
messages: mRNA cap-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. In the eIF-3 complex, eif3d specifically recognizes and binds the 7-methylguanosine cap of a subset of mRNAs.

244447:pus1
gene id: 244447:pus1
uniprot id: A0A3P8UXX0
names: Similarity
messages: Belongs to the tRNA pseudouridine synthase TruA family.

244447:kif21b
gene id: 244447:kif21b
uniprot id: A0A3P8UXD8
uniprot id: A0A3P8V651
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
messages: cytoskeleton

244447:fgg
gene id: 244447:fgg
uniprot id: A0A3P8USI7
names: Subcellular Location Annotation
names: Subunit
messages: Heterohexamer; disulfide linked. Contains 2 sets of 3 non-identical chains (alpha, beta and gamma). The 2 heterotrimers are in head to head conformation with the N-termini in a small central domain.
messages: Secreted

244447:LOC103396165
gene id: 244447:LOC103396165
uniprot id: A0A3P8WTR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/PBX homeobox family.
messages: Nucleus

244447:LOC103399873
gene id: 244447:LOC103399873
uniprot id: A0A3P8UKH9
names: Function
messages: Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Binds to G(i)-alpha and G(o)-alpha, but not to G(s)-alpha.

244447:frk
gene id: 244447:frk
uniprot id: A0A3P8WJ80
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

244447:pkp4
gene id: 244447:pkp4
uniprot id: A0A3P8VX76
names: Similarity
messages: Belongs to the beta-catenin family.

244447:LOC103395001
gene id: 244447:LOC103395001
uniprot id: A0A3P8WN17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

244447:mast3
gene id: 244447:mast3
uniprot id: A0A3P8WQD6
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.

244447:unc45b
gene id: 244447:unc45b
uniprot id: A0A3P8WKT8
names: Subcellular Location Annotation
messages: A band
messages: Z line
messages: perinuclear region

244447:mospd1
gene id: 244447:mospd1
uniprot id: A0A3P8WHJ9
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Membrane

244447:LOC103384096
gene id: 244447:LOC103384096
uniprot id: A0A3P8VT33
names: Similarity
messages: Belongs to the cytochrome P450 family.

244447:slc1a4
gene id: 244447:slc1a4
uniprot id: A0A3P8UDI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

244447:hrh1
gene id: 244447:hrh1
uniprot id: A0A3P8X453
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

244447:zfhx4
gene id: 244447:zfhx4
uniprot id: A0A3P8VIC6
names: Subcellular Location Annotation
messages: Nucleus

244447:atg16l1
gene id: 244447:atg16l1
uniprot id: A0A3P8VIV0
names: Similarity
messages: Belongs to the WD repeat ATG16 family.

244447:LOC103385136
gene id: 244447:LOC103385136
uniprot id: A0A3P8VB40
names: Similarity
messages: Belongs to the TAFA family.

244447:LOC103382893
gene id: 244447:LOC103382893
uniprot id: A0A3P8VV62
names: Similarity
messages: Belongs to the aldo/keto reductase family.

244447:LOC103390711
gene id: 244447:LOC103390711
uniprot id: A0A3P8V3S8
names: Similarity
messages: Belongs to the peptidase C1 family.

244447:haus1
gene id: 244447:haus1
uniprot id: A0A3P8WUV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAUS1 family.
messages: spindle

244447:parn
gene id: 244447:parn
uniprot id: A0A3P8UMQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAF1 family.
messages: Cytoplasm
messages: Nucleus

244447:LOC103393515
gene id: 244447:LOC103393515
uniprot id: A0A3P8W3R3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. Insulin receptor subfamily.
messages: Cell membrane
messages: Membrane

244447:LOC103386885
gene id: 244447:LOC103386885
uniprot id: A0A3P8UG84
names: Subcellular Location Annotation
messages: Nucleus

244447:LOC103379738
gene id: 244447:LOC103379738
uniprot id: A0A3P8UD74
names: Subcellular Location Annotation
messages: Nucleus
messages: telomere

244447:mrpl28
gene id: 244447:mrpl28
uniprot id: A0A3P8VB29
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

244447:LOC103391592
gene id: 244447:LOC103391592
uniprot id: A0A3P8UXD7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Ras family.
messages: Endosome membrane
messages: Recycling endosome membrane

244447:LOC103393222
gene id: 244447:LOC103393222
uniprot id: A0A3P8WJB5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the V-ATPase proteolipid subunit family.
messages: Membrane
messages: Proton-conducting pore forming of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex. The V1 complex consists of three catalytic AB heterodimers that form a heterohexamer, three peripheral stalks each consisting of EG heterodimers, one central rotor including subunits D and F, and the regulatory subunits C and H. The proton translocation complex V0 consists of the proton transport subunit a, a ring of proteolipid subunits c9c'', rotary subunit d, subunits e and f, and the accessory subunits.
messages: Vacuole membrane
messages: clathrin-coated vesicle membrane
messages: synaptic vesicle membrane

244447:LOC103379853
gene id: 244447:LOC103379853
uniprot id: A0A3P8UFS4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cyclin family. Cyclin AB subfamily.
messages: Belongs to the cyclin family. Cyclin D subfamily.
messages: Cytoplasm
messages: Essential for the control of the cell cycle at the G2/M (mitosis) transition.
messages: Interacts with the CDK1 protein kinase to form a serine/threonine kinase holoenzyme complex also known as maturation promoting factor (MPF). The cyclin subunit imparts substrate specificity to the complex.
messages: Nucleus

244447:LOC103386836
gene id: 244447:LOC103386836
uniprot id: A0A3P8WYY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ISY1 family.
messages: Nucleus

244447:LOC103398206
gene id: 244447:LOC103398206
uniprot id: A0A3P8UJF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

244447:rpap2
gene id: 244447:rpap2
uniprot id: A0A3P8WQE9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with the RNA polymerase II complex.
messages: Belongs to the RPAP2 family.
messages: Nucleus
messages: Protein phosphatase that displays CTD phosphatase activity and regulates transcription of snRNA genes. Recognizes and binds phosphorylated 'Ser-7' of the C-terminal heptapeptide repeat domain (CTD) of the largest RNA polymerase II subunit POLR2A, and mediates dephosphorylation of 'Ser-5' of the CTD, thereby promoting transcription of snRNA genes.

244447:LOC103386163
gene id: 244447:LOC103386163
uniprot id: A0A3P8V2W8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

244447:neto2
gene id: 244447:neto2
uniprot id: A0A3P8VE38
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

244447:LOC103385893
gene id: 244447:LOC103385893
uniprot id: A0A3P8UMC5
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

244447:pomgnt2
gene id: 244447:pomgnt2
uniprot id: A0A3P8VTS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 61 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

244447:LOC103390507
gene id: 244447:LOC103390507
uniprot id: A0A3P8UKG8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DRC1 family.
messages: Component of the nexin-dynein regulatory complex (N-DRC).
messages: cilium axoneme
messages: flagellum axoneme

244447:LOC103391504
gene id: 244447:LOC103391504
uniprot id: A0A3P8X507
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

244447:ppa2
gene id: 244447:ppa2
uniprot id: A0A3P8UQW0
names: Similarity
messages: Belongs to the PPase family.

244447:prkrip1
gene id: 244447:prkrip1
uniprot id: A0A3P8WQJ7
names: Similarity
messages: Belongs to the PRKRIP1 family.

244447:LOC103394585
gene id: 244447:LOC103394585
uniprot id: A0A3P8VB85
names: Subcellular Location Annotation
messages: Membrane

244447:LOC103394812
gene id: 244447:LOC103394812
uniprot id: A0A3P8W6J0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family.
messages: Membrane

244447:LOC103394525
gene id: 244447:LOC103394525
uniprot id: A0A3P8VAV9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ephrin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

244447:trappc5
gene id: 244447:trappc5
uniprot id: A0A3P8WDP8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAPP small subunits family. BET3 subfamily.
messages: Endoplasmic reticulum
messages: May play a role in vesicular transport from endoplasmic reticulum to Golgi.
messages: Part of the multisubunit TRAPP (transport protein particle) complex.
messages: cis-Golgi network

244447:ogfod1
gene id: 244447:ogfod1
uniprot id: A0A3P8UPT0
names: Similarity
messages: Belongs to the TPA1 family.

244447:mpc2
gene id: 244447:mpc2
uniprot id: A0A3P8UST3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family.
messages: Mediates the uptake of pyruvate into mitochondria.
messages: Membrane
messages: Mitochondrion inner membrane

244447:LOC103387725
gene id: 244447:LOC103387725
uniprot id: B2D2I4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Conversion of pregnenolone and progesterone to their 17-alpha-hydroxylated products and subsequently to dehydroepiandrosterone (DHEA) and androstenedione. Catalyzes both the 17-alpha-hydroxylation and the 17,20-lyase reaction.
messages: Membrane

244447:lsm12
gene id: 244447:lsm12
uniprot id: A0A3P8VKS3
names: Similarity
messages: Belongs to the LSM12 family.

244447:LOC103379729
gene id: 244447:LOC103379729
uniprot id: A0A3P8X2U1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 1 family. Gal/GlcNAc/GalNAc subfamily.
messages: Membrane

244447:ap5m1
gene id: 244447:ap5m1
uniprot id: A0A3P8UF27
names: Subcellular Location Annotation
names: Subunit
messages: Lysosome membrane
messages: Membrane
messages: Probably part of the adaptor protein complex 5 (AP-5) a tetramer composed of AP5B1, AP5M1, AP5S1 and AP5Z1.

244447:plin2
gene id: 244447:plin2
uniprot id: A0A3P8VP63
names: Similarity
messages: Belongs to the perilipin family.

244447:enpp4
gene id: 244447:enpp4
uniprot id: A0A3P8VJ56
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide pyrophosphatase/phosphodiesterase family.
messages: Cell membrane
messages: Hydrolyzes extracellular Ap3A into AMP and ADP, and Ap4A into AMP and ATP. Ap3A and Ap4A are diadenosine polyphosphates thought to induce proliferation of vascular smooth muscle cells. Acts as a procoagulant, mediating platelet aggregation at the site of nascent thrombus via release of ADP from Ap3A and activation of ADP receptors.
messages: Membrane

244447:zpr1
gene id: 244447:zpr1
uniprot id: A0A3P8WLW6
names: Similarity
messages: Belongs to the ZPR1 family.

244447:LOC103391289
gene id: 244447:LOC103391289
uniprot id: A0A3P8WJ15
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

244447:LOC103385960
gene id: 244447:LOC103385960
uniprot id: A0A3P8UJ22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Vang family.
messages: Cell membrane
messages: Membrane

244447:ppcs
gene id: 244447:ppcs
uniprot id: A0A3P8X4H6
uniprot id: A0A3P8X691
names: Similarity
messages: Belongs to the PPC synthetase family.

244447:LOC103384242
gene id: 244447:LOC103384242
uniprot id: A0A3P8WBY4
names: Subcellular Location Annotation
messages: Membrane

244447:dph2
gene id: 244447:dph2
uniprot id: A0A3P8VZ83
names: Function
names: Similarity
messages: Belongs to the DPH1/DPH2 family. DPH2 subfamily.
messages: Required for the first step of diphthamide biosynthesis, a post-translational modification of histidine which occurs in elongation factor 2. DPH1 and DPH2 transfer a 3-amino-3-carboxypropyl (ACP) group from S-adenosyl-L-methionine (SAM) to a histidine residue, the reaction is assisted by a reduction system comprising DPH3 and a NADH-dependent reductase. Facilitates the reduction of the catalytic iron-sulfur cluster found in the DPH1 subunit.

244447:steap2
gene id: 244447:steap2
uniprot id: A0A3P8VQT7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STEAP family.
messages: Endosome membrane
messages: Membrane

244447:fgf13
gene id: 244447:fgf13
uniprot id: A0A3P8V1V5
uniprot id: A0A3P8V1Y1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heparin-binding growth factors family.
messages: Cytoplasm
messages: dendrite
messages: filopodium
messages: growth cone
messages: sarcolemma

244447:LOC103380040
gene id: 244447:LOC103380040
uniprot id: A0A3P8UU24
uniprot id: A0A3P8UU29
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. WEE1 subfamily.
messages: Binds 2 magnesium ions per subunit.
messages: Nucleus

244447:trap1
gene id: 244447:trap1
uniprot id: A0A3P8WFF7
names: Similarity
messages: Belongs to the heat shock protein 90 family.

244447:gstz1
gene id: 244447:gstz1
uniprot id: A0A3P8UDQ0
uniprot id: A0A3P8UJR3
names: Similarity
messages: Belongs to the GST superfamily. Zeta family.

244447:ufm1
gene id: 244447:ufm1
uniprot id: A0A3P8X044
names: Function
names: Similarity
messages: Belongs to the UFM1 family.
messages: Ubiquitin-like modifier which can be covalently attached via an isopeptide bond to lysine residues of substrate proteins as a monomer or a lysine-linked polymer. Ufmylation is involved in reticulophagy (also called ER-phagy) induced in response to endoplasmic reticulum stress.

244447:noc2l
gene id: 244447:noc2l
uniprot id: A0A3P8V9V5
names: Similarity
messages: Belongs to the NOC2 family.

244447:dync1li2
gene id: 244447:dync1li2
uniprot id: A0A3P8ULW2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes.
messages: Belongs to the dynein light intermediate chain family.
messages: Homodimer. The cytoplasmic dynein 1 complex consists of two catalytic heavy chains (HCs) and a number of non-catalytic subunits presented by intermediate chains (ICs).
messages: cytoskeleton

244447:LOC103387156
gene id: 244447:LOC103387156
uniprot id: A0A3P8V053
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELO family.
messages: Membrane

244447:LOC103382701
gene id: 244447:LOC103382701
uniprot id: A0A3P8VBT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

244447:znf330
gene id: 244447:znf330
uniprot id: A0A3P8X601
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOA36 family.
messages: nucleolus

244447:LOC103386224
gene id: 244447:LOC103386224
uniprot id: A0A3P8V3C4
names: Similarity
messages: Belongs to the PDE6D/unc-119 family.

244447:LOC103385296
gene id: 244447:LOC103385296
uniprot id: A0A3P8WSE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/IRO homeobox family.
messages: Nucleus

244447:LOC103387889
gene id: 244447:LOC103387889
uniprot id: A0A3P8WYS4
names: Similarity
messages: Belongs to the cytochrome P450 family.

244447:LOC103388348
gene id: 244447:LOC103388348
uniprot id: A0A3P8UW57
names: Similarity
messages: Belongs to the CUT homeobox family.

244447:sptssa
gene id: 244447:sptssa
uniprot id: A0A3P8VV83
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

244447:pif1
gene id: 244447:pif1
uniprot id: A0A3P8VZP4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the helicase family. PIF1 subfamily.
messages: DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability.
messages: Mitochondrion
messages: Monomer.
messages: Nucleus

244447:seh1l
gene id: 244447:seh1l
uniprot id: A0A3P8W602
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat SEC13 family.
messages: Component of the Nup107-160 subcomplex of the nuclear pore complex (NPC). The Nup107-160 subcomplex is required for the assembly of a functional NPC. The Nup107-160 subcomplex is also required for normal kinetochore microtubule attachment, mitotic progression and chromosome segregation. This subunit plays a role in recruitment of the Nup107-160 subcomplex to the kinetochore.
messages: Lysosome membrane
messages: kinetochore

244447:capza2
gene id: 244447:capza2
uniprot id: A0A3P8X5G7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the F-actin-capping protein alpha subunit family.
messages: F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.
messages: Heterodimer of an alpha and a beta subunit.

244447:tnfaip1
gene id: 244447:tnfaip1
uniprot id: A0A3P8UVD9
names: Similarity
messages: Belongs to the BACURD family.

244447:LOC103390745
gene id: 244447:LOC103390745
uniprot id: A0A3P8UWA6
names: Similarity
messages: Belongs to the TMEM121 family.

244447:thoc7
gene id: 244447:thoc7
uniprot id: A0A3P8V3X8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the THOC7 family.
messages: Nucleus
messages: Required for efficient export of polyadenylated RNA. Acts as component of the THO subcomplex of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and which specifically associates with spliced mRNA and not with unspliced pre-mRNA. TREX is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5' end of the mRNA where it functions in mRNA export to the cytoplasm via the TAP/NFX1 pathway.

244447:lmf2
gene id: 244447:lmf2
uniprot id: A0A3P8V194
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lipase maturation factor family.
messages: Endoplasmic reticulum membrane
messages: Involved in the maturation of specific proteins in the endoplasmic reticulum.
messages: Membrane

244447:LOC103389767
gene id: 244447:LOC103389767
uniprot id: A0A3P8W2L0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NALF family.
messages: Membrane

244447:map1lc3c
gene id: 244447:map1lc3c
uniprot id: A0A3P8UIJ1
names: Similarity
messages: Belongs to the ATG8 family.

244447:LOC103385675
gene id: 244447:LOC103385675
uniprot id: A0A3P8X2E6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

244447:LOC103397350
gene id: 244447:LOC103397350
uniprot id: A0A3P8X2W3
names: Subcellular Location Annotation
messages: Nucleus

244447:gucy1a2
gene id: 244447:gucy1a2
uniprot id: A0A3P8WR20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Cytoplasm

244447:hoxc13
gene id: 244447:hoxc13
uniprot id: A0A3P8VDU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus

244447:mtx2
gene id: 244447:mtx2
uniprot id: A0A3P8WKR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metaxin family.
messages: Membrane
messages: Mitochondrion outer membrane

244447:irf2bpl
gene id: 244447:irf2bpl
uniprot id: A0A3P8VXJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IRF2BP family.
messages: Nucleus

244447:LOC103392706
gene id: 244447:LOC103392706
uniprot id: A0A3P8VI50
names: Similarity
messages: Belongs to the fructosamine kinase family.

244447:capg
gene id: 244447:capg
uniprot id: A0A3P8ULF2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the villin/gelsolin family.
messages: Calcium-sensitive protein which reversibly blocks the barbed ends of actin filaments but does not sever preformed actin filaments. May play an important role in macrophage function. May play a role in regulating cytoplasmic and/or nuclear structures through potential interactions with actin. May bind DNA.
messages: Cytoplasm
messages: Melanosome
messages: Nucleus
messages: lamellipodium
messages: ruffle

244447:itfg1
gene id: 244447:itfg1
uniprot id: A0A3P8VMB9
names: Similarity
messages: Belongs to the TIP family.

244447:LOC103386215
gene id: 244447:LOC103386215
uniprot id: A0A3P8V4D1
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lysyl oxidase family.
messages: Contains 1 lysine tyrosylquinone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mediates the post-translational oxidative deamination of lysine residues on target proteins leading to the formation of deaminated lysine (allysine).
messages: The lysine tyrosylquinone cross-link (LTQ) is generated by condensation of the epsilon-amino group of a lysine with a topaquinone produced by oxidation of tyrosine.
messages: extracellular space

244447:LOC103396368
gene id: 244447:LOC103396368
uniprot id: A0A3P8VXJ4
names: Subcellular Location Annotation
messages: Synapse

244447:KEH01 p03
gene id: 244447:KEH01_p03
uniprot id: C5H0G3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 5 family.
messages: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I.
messages: Membrane
messages: Mitochondrion inner membrane

244447:LOC103389960
gene id: 244447:LOC103389960
uniprot id: A0A3P8V1F4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RAMP4 family.
messages: Endoplasmic reticulum membrane
messages: May interact with target proteins during translocation into the lumen of the endoplasmic reticulum. May protect unfolded target proteins against degradation and facilitate correct glycosylation.
messages: Membrane

244447:ncaph
gene id: 244447:ncaph
uniprot id: A0A3P8W999
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CND2 (condensin subunit 2) family.
messages: Chromosome
messages: Cytoplasm
messages: Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes.

244447:mrpl14
gene id: 244447:mrpl14
uniprot id: A0A3P8VSK9
names: Similarity
messages: Belongs to the universal ribosomal protein uL14 family.

244447:LOC103390024
gene id: 244447:LOC103390024
uniprot id: A0A3P8V2Y4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the X(+)/potassium ATPases subunit beta family.
messages: Membrane
messages: This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane.

244447:LOC103392522
gene id: 244447:LOC103392522
uniprot id: A0A3P8X2Y3
names: Similarity
messages: Belongs to the universal ribosomal protein uL3 family.

244447:LOC103386736
gene id: 244447:LOC103386736
uniprot id: A0A3P8X260
names: Similarity
messages: Belongs to the cytochrome P450 family.

244447:foxd1
gene id: 244447:foxd1
uniprot id: A0A3P8W1A6
names: Subcellular Location Annotation
messages: Nucleus

244447:LOC103394644
gene id: 244447:LOC103394644
uniprot id: A0A3P8VPB7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit I family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
messages: Cytoplasm

244447:LOC103390073
gene id: 244447:LOC103390073
uniprot id: A0A3P8WCG7
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily.

244447:reep3
gene id: 244447:reep3
uniprot id: A0A3P8VU58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DP1 family.
messages: Membrane

244447:prlr
gene id: 244447:prlr
uniprot id: A0A3P8WWL9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type I cytokine receptor family. Type 1 subfamily.
messages: Membrane
messages: The WSXWS motif appears to be necessary for proper protein folding and thereby efficient intracellular transport and cell-surface receptor binding.
messages: The box 1 motif is required for JAK interaction and/or activation.
messages: This is a receptor for the anterior pituitary hormone prolactin.

244447:il17d
gene id: 244447:il17d
uniprot id: A0A3P8VFB2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-17 family.
messages: Secreted

244447:adipor1
gene id: 244447:adipor1
uniprot id: A0A3P8V065
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

244447:dda1
gene id: 244447:dda1
uniprot id: A0A3P8WMM4
names: Similarity
messages: Belongs to the DDA1 family.

244447:naa60
gene id: 244447:naa60
uniprot id: A0A3P8WHY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetyltransferase family. NAA60 subfamily.
messages: Golgi apparatus membrane

244447:metap1
gene id: 244447:metap1
uniprot id: A0A3P8UCF0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).

244447:ipo7
gene id: 244447:ipo7
uniprot id: A0A3P8VN92
names: Subcellular Location Annotation
messages: Cytoplasm

244447:axl
gene id: 244447:axl
uniprot id: A0A3P8V8E8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.
messages: Cell membrane
messages: Membrane

244447:atxn10
gene id: 244447:atxn10
uniprot id: A0A3P8VUT4
names: Function
names: Similarity
messages: Belongs to the ataxin-10 family.
messages: Necessary for the survival of cerebellar neurons. Induces neuritogenesis by activating the Ras-MAP kinase pathway. May play a role in the maintenance of a critical intracellular glycosylation level and homeostasis.

244447:foxn2
gene id: 244447:foxn2
uniprot id: A0A3P8VW37
names: Subcellular Location Annotation
messages: Nucleus

244447:LOC103396539
gene id: 244447:LOC103396539
uniprot id: A0A3P8WJ99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Endoplasmic reticulum membrane

244447:zdhhc3
gene id: 244447:zdhhc3
uniprot id: A0A3P8VXX1
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

244447:zcchc8
gene id: 244447:zcchc8
uniprot id: A0A3P8WBT1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZCCHC8 family.
messages: nucleoplasm

244447:LOC103388842
gene id: 244447:LOC103388842
uniprot id: A0A3P8VXW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tumor necrosis factor family.
messages: Membrane

244447:LOC107989131
gene id: 244447:LOC107989131
uniprot id: A0A3P8V4W9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the natriuretic peptide family.
messages: Secreted

244447:LOC103389480
gene id: 244447:LOC103389480
uniprot id: A0A3P8V0G8
names: Similarity
messages: Belongs to the eIF4E-binding protein family.

244447:LOC103388563
gene id: 244447:LOC103388563
uniprot id: A0A3P8V0Z0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine alpha (chemokine CxC) family.
messages: Secreted

244447:cfap36
gene id: 244447:cfap36
uniprot id: A0A3P8UHA3
uniprot id: A0A3P8UHB2
names: Similarity
messages: Belongs to the CFAP36 family.

244447:LOC103397671
gene id: 244447:LOC103397671
uniprot id: A0A3P8WLT5
uniprot id: A0A3P8WMK9
uniprot id: A0A3P8WMP3
uniprot id: A0A3P8WT12
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class CDC14 subfamily.

244447:LOC103393598
gene id: 244447:LOC103393598
uniprot id: A0A3P8W374
names: Subcellular Location Annotation
messages: Membrane
messages: chromaffin granule membrane

244447:LOC103382603
gene id: 244447:LOC103382603
uniprot id: A0A3P8V061
names: Subcellular Location Annotation
messages: cytoskeleton

244447:lbx1
gene id: 244447:lbx1
uniprot id: A0A3P8WCA2
names: Subcellular Location Annotation
messages: Nucleus

244447:LOC103392222
gene id: 244447:LOC103392222
uniprot id: A0A3P8W0F9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

244447:rtn1
gene id: 244447:rtn1
uniprot id: A0A3P8UG57
uniprot id: A0A3P8UPK0
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

244447:LOC103396470
gene id: 244447:LOC103396470
uniprot id: A0A3P8WFJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calreticulin family.
messages: Endoplasmic reticulum lumen

244447:LOC103382085
gene id: 244447:LOC103382085
uniprot id: A0A3P8X1L7
names: Similarity
messages: Belongs to the protein kinase superfamily.

244447:LOC103384644
gene id: 244447:LOC103384644
uniprot id: A0A3P8UJK1
names: Similarity
messages: Belongs to the vacuolar ATPase subunit S1 family.

244447:bmp6
gene id: 244447:bmp6
uniprot id: A0A0U1WUR9
names: Similarity
messages: Belongs to the TGF-beta family.

244447:LOC103377104
gene id: 244447:LOC103377104
uniprot id: A0A3P8W935
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

244447:LOC103394559
gene id: 244447:LOC103394559
uniprot id: A0A3P8V7D0
uniprot id: A0A3P8V8J4
names: Subcellular Location Annotation
messages: Nucleus

244447:fcf1
gene id: 244447:fcf1
uniprot id: A0A3P8UCS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UTP23/FCF1 family. FCF1 subfamily.
messages: nucleolus

244447:fam45a
gene id: 244447:fam45a
uniprot id: A0A3P8VTW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DENND10 family.
messages: Endosome
messages: Late endosome

244447:mpv17l
gene id: 244447:mpv17l
uniprot id: A0A3P8VZK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxisomal membrane protein PXMP2/4 family.
messages: Membrane

244447:LOC103389737
gene id: 244447:LOC103389737
uniprot id: A0A3P8W8P9
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Endoplasmic reticulum
messages: Nucleus

244447:LOC103389355
gene id: 244447:LOC103389355
uniprot id: A0A3P8UKP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily.
messages: Membrane

244447:mre11
gene id: 244447:mre11
uniprot id: A0A3P8WFM3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MRE11/RAD32 family.
messages: Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.
messages: Nucleus

244447:LOC103378384
gene id: 244447:LOC103378384
uniprot id: A0A3P8WDK2
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

244447:prox1
gene id: 244447:prox1
uniprot id: A0A3P8X4R7
names: Subcellular Location Annotation
messages: Nucleus

244447:fxn
gene id: 244447:fxn
uniprot id: A0A3P8VHB6
names: Similarity
messages: Belongs to the frataxin family.

244447:med4
gene id: 244447:med4
uniprot id: A0A3P8WZZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 4 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

244447:dph1
gene id: 244447:dph1
uniprot id: A0A3P8W4B3
names: Similarity
messages: Belongs to the DPH1/DPH2 family. DPH1 subfamily.

244447:vegfd
gene id: 244447:vegfd
uniprot id: A0A3P8UMS0
names: Similarity
messages: Belongs to the PDGF/VEGF growth factor family.

244447:LOC103378673
gene id: 244447:LOC103378673
uniprot id: A0A3P8UQW5
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

244447:LOC103381669
gene id: 244447:LOC103381669
uniprot id: A0A3P8VZI1
names: Similarity
messages: Belongs to the cytochrome P450 family.

244447:LOC103379523
gene id: 244447:LOC103379523
uniprot id: A0A3P8X5W1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paired homeobox family.
messages: Nucleus

244447:rpl34
gene id: 244447:rpl34
uniprot id: A0A3P8VA17
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL34 family.

244447:gab1
gene id: 244447:gab1
uniprot id: A0A3P8X206
names: Similarity
messages: Belongs to the GAB family.

244447:suv39h1
gene id: 244447:suv39h1
uniprot id: A0A3P8V215
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. Suvar3-9 subfamily.
messages: Nucleus
messages: centromere

244447:itga4
gene id: 244447:itga4
uniprot id: A0A3P8V0Q2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

244447:elp2
gene id: 244447:elp2
uniprot id: A0A3P8VEV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat ELP2 family.
messages: Cytoplasm
messages: Nucleus

244447:vps26b
gene id: 244447:vps26b
uniprot id: A0A3P8W872
names: Similarity
messages: Belongs to the VPS26 family.

244447:LOC103391033
gene id: 244447:LOC103391033
uniprot id: A0A3P8VRU5
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

244447:egr1
gene id: 244447:egr1
uniprot id: A0A3P8WAM2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EGR C2H2-type zinc-finger protein family.
messages: Nucleus
messages: Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death.

244447:srp19
gene id: 244447:srp19
uniprot id: A0A3P8VK12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SRP19 family.
messages: Cytoplasm

244447:sirt2
gene id: 244447:sirt2
uniprot id: A0A3P8WA55
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the sirtuin family. Class I subfamily.
messages: Binds 1 zinc ion per subunit.
messages: NAD-dependent protein deacetylase.

244447:LOC103393619
gene id: 244447:LOC103393619
uniprot id: A0A3P8WEM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELO family.
messages: Membrane

244447:LOC103389171
gene id: 244447:LOC103389171
uniprot id: A0A3P8V062
names: Similarity
messages: Belongs to the FHIP family.

244447:LOC103384719
gene id: 244447:LOC103384719
uniprot id: A0A3P8URW6
uniprot id: A0A3P8UWI7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIB subfamily.
messages: Catalyzes the hydrolysis of ATP coupled with the transport of calcium.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

244447:LOC103385882
gene id: 244447:LOC103385882
uniprot id: A0A3P8URX6
names: Similarity
messages: Belongs to the CDI family.

244447:LOC103391089
gene id: 244447:LOC103391089
uniprot id: A0A3P8W6A5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complexin/synaphin family.
messages: Synapse

244447:chrna5
gene id: 244447:chrna5
uniprot id: A0A3P8W248
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

244447:abcd3
gene id: 244447:abcd3
uniprot id: A0A3P8VMH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCD family. Peroxisomal fatty acyl CoA transporter (TC 3.A.1.203) subfamily.
messages: Membrane
messages: Peroxisome membrane

244447:LOC103387652
gene id: 244447:LOC103387652
uniprot id: I7FE63
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GnRH family.
messages: Secreted
messages: Stimulates the secretion of gonadotropins.

244447:rabep1
gene id: 244447:rabep1
uniprot id: A0A3P8WD33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the rabaptin family.
messages: Cytoplasm
messages: Early endosome
messages: Endosome

244447:LOC103378549
gene id: 244447:LOC103378549
uniprot id: A0A3P8WY13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family.
messages: Endoplasmic reticulum

244447:eif6
gene id: 244447:eif6
uniprot id: A0A3P8WUI6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-6 family.
messages: Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. May also be involved in ribosome biogenesis.
messages: Cytoplasm
messages: Monomer. Associates with the 60S ribosomal subunit.
messages: nucleolus

244447:LOC103390969
gene id: 244447:LOC103390969
uniprot id: A0A3P8VN89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tom5 family.
messages: Membrane
messages: Mitochondrion outer membrane

244447:LOC103388924
gene id: 244447:LOC103388924
uniprot id: A0A3P8UZR2
names: Function
names: Subcellular Location Annotation
messages: Catalyzes the hydrolysis of phosphatidylinositol-4,5-bisphosphate (PtdIns-4,5-P2) to phosphatidylinositol-4-phosphate (PtdIns-4-P).
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane
messages: Membrane

244447:aacs
gene id: 244447:aacs
uniprot id: A0A3P8VCJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Converts acetoacetate to acetoacetyl-CoA in the cytosol.
messages: cytosol

244447:pdpk1
gene id: 244447:pdpk1
uniprot id: A0A3P8VUX8
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PDPK1 subfamily.

244447:begain
gene id: 244447:begain
uniprot id: A0A3P8UTM3
names: Subcellular Location Annotation
messages: Membrane

244447:smpdl3b
gene id: 244447:smpdl3b
uniprot id: A0A3P8WTI4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acid sphingomyelinase family.
messages: Binds 2 Zn(2+) per subunit.
messages: Secreted

244447:riok3
gene id: 244447:riok3
uniprot id: A0A3P8WSW5
names: Similarity
messages: Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.

244447:neu1
gene id: 244447:neu1
uniprot id: A0A3P8VW92
names: Similarity
messages: Belongs to the glycosyl hydrolase 33 family.

244447:tmem151b
gene id: 244447:tmem151b
uniprot id: A0A3P8WY81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM151 family.
messages: Membrane

244447:chst3
gene id: 244447:chst3
uniprot id: A0A3P8WNU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 1 family. Gal/GlcNAc/GalNAc subfamily.
messages: Membrane

244447:nupr1
gene id: 244447:nupr1
uniprot id: A0A3P8VVU7
names: Similarity
messages: Belongs to the NUPR family.

244447:LOC103385344
gene id: 244447:LOC103385344
uniprot id: A0A3P8WUD6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. L1/neurofascin/NgCAM family.
messages: Membrane

244447:LOC103382424
gene id: 244447:LOC103382424
uniprot id: A0A3P8UXC9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Membrane

244447:LOC103380013
gene id: 244447:LOC103380013
uniprot id: A0A3P8UWS1
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

244447:LOC103390897
gene id: 244447:LOC103390897
uniprot id: A0A3P8V600
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

244447:LOC103384145
gene id: 244447:LOC103384145
uniprot id: A0A3P8W2L4
names: Similarity
messages: Belongs to the glycosyltransferase 25 family.

244447:LOC103394926
gene id: 244447:LOC103394926
uniprot id: A0A3P8WNH9
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. SYK/ZAP-70 subfamily.

244447:LOC103388042
gene id: 244447:LOC103388042
uniprot id: A0A3P8WZC4
uniprot id: A0A3P8X2Q4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tropomyosin family.
messages: cytoskeleton

244447:fa2h
gene id: 244447:fa2h
uniprot id: A0A3P8W4V8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sterol desaturase family. SCS7 subfamily.
messages: Binds 2 Zn(2+) ions per subunit that likely form a catalytic dimetal center.
messages: Catalyzes stereospecific hydroxylation of free fatty acids at the C-2 position to produce (R)-2-hydroxy fatty acids, which are building blocks of sphingolipids and glycosphingolipids common in neural tissue and epidermis. Plays an essential role in the synthesis of galactosphingolipids of the myelin sheath. Responsible for the synthesis of sphingolipids and glycosphingolipids involved in the formation of epidermal lamellar bodies critical for skin permeability barrier. Participates in the synthesis of glycosphingolipids and a fraction of type II wax diesters in sebaceous gland, specifically regulating hair follicle homeostasis. Involved in the synthesis of sphingolipids of plasma membrane rafts, controlling lipid raft mobility and trafficking of raft-associated proteins.
messages: Endoplasmic reticulum membrane
messages: Membrane

244447:ak4
gene id: 244447:ak4
uniprot id: A0A3P8WMV6
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family. AK3 subfamily.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon GTP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent GTP hydrolysis.
messages: Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mitochondrion matrix
messages: Monomer.

244447:entpd4
gene id: 244447:entpd4
uniprot id: A0A3P8W8D2
names: Similarity
messages: Belongs to the GDA1/CD39 NTPase family.

244447:epn2
gene id: 244447:epn2
uniprot id: A0A3P8WRT8
names: Similarity
messages: Belongs to the epsin family.

244447:LOC103381485
gene id: 244447:LOC103381485
uniprot id: A0A3P8VFC1
uniprot id: A0A3P8VFC6
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

244447:LOC103396244
gene id: 244447:LOC103396244
uniprot id: A0A3P8WS73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

244447:LOC103389755
gene id: 244447:LOC103389755
uniprot id: A0A3P8W448
names: Subcellular Location Annotation
messages: Lysosome membrane
messages: Membrane

244447:grhl2
gene id: 244447:grhl2
uniprot id: A0A3P8W2Q7
names: Subcellular Location Annotation
messages: Nucleus

244447:LOC103384205
gene id: 244447:LOC103384205
uniprot id: A0A3P8WCK5
uniprot id: A0A3P8WCL3
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

244447:atp8b2
gene id: 244447:atp8b2
uniprot id: A0A3P8US60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

244447:prkca
gene id: 244447:prkca
uniprot id: A0A3P8VU68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
messages: Cytoplasm
messages: Membrane

244447:snx2
gene id: 244447:snx2
uniprot id: A0A3P8VL04
uniprot id: A0A3P8VRC3
names: Similarity
messages: Belongs to the sorting nexin family.

244447:LOC103381661
gene id: 244447:LOC103381661
uniprot id: A0A3P8VY27
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase 116 kDa subunit family.
messages: Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.
messages: Membrane

244447:trnau1ap
gene id: 244447:trnau1ap
uniprot id: A0A3P8VAW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM TRSPAP family.
messages: Cytoplasm
messages: Nucleus

244447:eif2d
gene id: 244447:eif2d
uniprot id: A0A3P8X2K6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eIF2D family.
messages: Cytoplasm
messages: Translation initiation factor that is able to deliver tRNA to the P-site of the eukaryotic ribosome in a GTP-independent manner. The binding of Met-tRNA(I) occurs after the AUG codon finds its position in the P-site of 40S ribosomes, the situation that takes place during initiation complex formation on some specific RNAs. Its activity in tRNA binding with 40S subunits does not require the presence of the aminoacyl moiety. Possesses the unique ability to deliver non-Met (elongator) tRNAs into the P-site of the 40S subunit. In addition to its role in initiation, can promote release of deacylated tRNA and mRNA from recycled 40S subunits following ABCE1-mediated dissociation of post-termination ribosomal complexes into subunits.

244447:LOC103394524
gene id: 244447:LOC103394524
uniprot id: A0A3P8V8B7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ephrin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

244447:LOC103395058
gene id: 244447:LOC103395058
uniprot id: A0A3P8WVK1
uniprot id: A0A3P8WVK5
names: Subcellular Location Annotation
messages: Membrane

244447:LOC103397916
gene id: 244447:LOC103397916
uniprot id: A0A3P8VB78
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat Groucho/TLE family.
messages: Nucleus

244447:LOC103396445
gene id: 244447:LOC103396445
uniprot id: A0A3P8W9F2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the E2F/DP family.
messages: Nucleus

244447:cwh2orf68
gene id: 244447:cwh2orf68
uniprot id: A0A3P8WLP9
names: Similarity
messages: Belongs to the UPF0561 family.

244447:LOC103381856
gene id: 244447:LOC103381856
uniprot id: A0A3P8WDJ9
names: Subcellular Location Annotation
messages: Nucleus

244447:tekt3
gene id: 244447:tekt3
uniprot id: A0A3P8WBC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tektin family.
messages: flagellum

244447:nup133
gene id: 244447:nup133
uniprot id: A0A3P8VWF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleoporin Nup133 family.
messages: nuclear pore complex

244447:LOC103392227
gene id: 244447:LOC103392227
uniprot id: A0A3P8VVE8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

244447:LOC103381009
gene id: 244447:LOC103381009
uniprot id: A0A3P8UL18
uniprot id: A0A3P8UQV0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ena/VASP family.
messages: lamellipodium
messages: stress fiber

244447:hsd17b10
gene id: 244447:hsd17b10
uniprot id: A0A3P8VIE9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

244447:LOC103385870
gene id: 244447:LOC103385870
uniprot id: A0A3P8WX50
uniprot id: A0A3P8WXP4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

244447:LOC103394483
gene id: 244447:LOC103394483
uniprot id: A0A3P8V5N8
names: Similarity
messages: Belongs to the peptidase C1 family.

244447:LOC103395151
gene id: 244447:LOC103395151
uniprot id: A0A3P8VNY2
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

244447:edn1
gene id: 244447:edn1
uniprot id: A0A3P8VL39
uniprot id: A0A3P8VRT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endothelin/sarafotoxin family.
messages: Secreted

244447:LOC103385636
gene id: 244447:LOC103385636
uniprot id: A0A3P8X4C4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paired homeobox family.
messages: Nucleus

244447:sf3a1
gene id: 244447:sf3a1
uniprot id: A0A3P8VR35
names: Subcellular Location Annotation
messages: Nucleus

244447:f3
gene id: 244447:f3
uniprot id: A0A3P8VJY0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tissue factor family.
messages: Initiates blood coagulation by forming a complex with circulating factor VII or VIIa. The [TF:VIIa] complex activates factors IX or X by specific limited proteolysis. TF plays a role in normal hemostasis by initiating the cell-surface assembly and propagation of the coagulation protease cascade.
messages: Interacts with HSPE; the interaction, inhibited by heparin, promotes the generation of activated factor X and activates coagulation in the presence of activated factor VII.

244447:LOC103379668
gene id: 244447:LOC103379668
uniprot id: A0A3P8X3G1
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MNB/DYRK subfamily.

244447:slc9a5
gene id: 244447:slc9a5
uniprot id: A0A3P8VBW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Membrane

244447:LOC103389281
gene id: 244447:LOC103389281
uniprot id: A0A3P8UG02
uniprot id: A0A3P8UI95
uniprot id: A0A3P8UN97
uniprot id: A0A3P8UPC1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. NR1/GRIN1 subfamily.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

244447:agt
gene id: 244447:agt
uniprot id: A0A3P8UQ50
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the serpin family.
messages: Essential component of the renin-angiotensin system (RAS), a potent regulator of blood pressure, body fluid and electrolyte homeostasis.
messages: Secreted
messages: Stimulates aldosterone release.

244447:LOC103392096
gene id: 244447:LOC103392096
uniprot id: A0A3P8VKE0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

244447:ubr1
gene id: 244447:ubr1
uniprot id: A0A3P8UDX0
names: Function
names: Similarity
messages: Belongs to the UBR1 family.
messages: Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.

244447:LOC103395876
gene id: 244447:LOC103395876
uniprot id: A0A3P8VV72
names: Function
names: Similarity
messages: Belongs to the calponin family.
messages: Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity.

244447:LOC103391635
gene id: 244447:LOC103391635
uniprot id: A0A3P8V069
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

244447:LOC103378014
gene id: 244447:LOC103378014
uniprot id: A0A3P8UKY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

244447:gck
gene id: 244447:gck
uniprot id: A0A0H3WED5
names: Similarity
messages: Belongs to the hexokinase family.

244447:ndst1
gene id: 244447:ndst1
uniprot id: A0A3P8VR15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 1 family. NDST subfamily.
messages: Membrane

244447:fam96a
gene id: 244447:fam96a
uniprot id: A0A3P8X2P1
names: Similarity
messages: Belongs to the MIP18 family.

244447:fut8
gene id: 244447:fut8
uniprot id: A0A3P8UTV2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 23 family.
messages: Catalyzes the addition of fucose in alpha 1-6 linkage to the first GlcNAc residue, next to the peptide chains in N-glycans.
messages: Golgi stack membrane
messages: Membrane

244447:LOC103380164
gene id: 244447:LOC103380164
uniprot id: A0A3P8VA68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM263 family.
messages: Membrane

244447:psap
gene id: 244447:psap
uniprot id: A0A3P8VZA1
uniprot id: A0A3P8VZB1
names: Function
names: Subcellular Location Annotation
messages: Prosaposin: Behaves as a myelinotrophic and neurotrophic factor, these effects are mediated by its G-protein-coupled receptors, GPR37 and GPR37L1, undergoing ligand-mediated internalization followed by ERK phosphorylation signaling.
messages: Saposins are specific low-molecular mass non-enzymic proteins, they participate in the lysosomal degradation of sphingolipids, which takes place by the sequential action of specific hydrolases.
messages: Secreted

244447:LOC103395219
gene id: 244447:LOC103395219
uniprot id: A0A3P8W041
names: Similarity
messages: Belongs to the heat shock protein 70 family.

244447:LOC103387620
gene id: 244447:LOC103387620
uniprot id: A0A3P8W101
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tom20 family.
messages: Membrane
messages: Mitochondrion outer membrane

244447:LOC103388769
gene id: 244447:LOC103388769
uniprot id: A0A3P8VT50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Early endosome
messages: Endosome
messages: Membrane

244447:atrnl1
gene id: 244447:atrnl1
uniprot id: A0A3P8VDN8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

244447:LOC103385970
gene id: 244447:LOC103385970
uniprot id: A0A3P8UEL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.
messages: Membrane

244447:alg11
gene id: 244447:alg11
uniprot id: A0A3P8VLB8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily.
messages: Endoplasmic reticulum membrane
messages: Required for N-linked oligosaccharide assembly.

244447:metrnl
gene id: 244447:metrnl
uniprot id: A0A3P8VLG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the meteorin family.
messages: Secreted

244447:ppp3ca
gene id: 244447:ppp3ca
uniprot id: A0A3P8VKI6
uniprot id: A0A3P8VNE7
names: Similarity
messages: Belongs to the PPP phosphatase family. PP-2B subfamily.

244447:LOC103380934
gene id: 244447:LOC103380934
uniprot id: A0A3P8X4J4
names: Subcellular Location Annotation
messages: Nucleus

244447:LOC103389425
gene id: 244447:LOC103389425
uniprot id: A0A3P8UZZ7
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pentraxin family.
messages: Binds 2 calcium ions per subunit.
messages: Homopentamer. Pentaxin (or pentraxin) have a discoid arrangement of 5 non-covalently bound subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

244447:pgr
gene id: 244447:pgr
uniprot id: A0A3P8VBI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

244447:ctnnbl1
gene id: 244447:ctnnbl1
uniprot id: A0A3P8UU90
names: Subcellular Location Annotation
messages: Nucleus

244447:marcks
gene id: 244447:marcks
uniprot id: A0A3P8WM51
names: Similarity
messages: Belongs to the MARCKS family.

244447:KEH01 p07
gene id: 244447:KEH01_p07
uniprot id: C5H0F9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Component of the cytochrome c oxidase (complex IV, CIV), a multisubunit enzyme composed of 14 subunits. The complex is composed of a catalytic core of 3 subunits MT-CO1, MT-CO2 and MT-CO3, encoded in the mitochondrial DNA, and 11 supernumerary subunits COX4I, COX5A, COX5B, COX6A, COX6B, COX6C, COX7A, COX7B, COX7C, COX8 and NDUFA4, which are encoded in the nuclear genome. The complex exists as a monomer or a dimer and forms supercomplexes (SCs) in the inner mitochondrial membrane with NADH-ubiquinone oxidoreductase (complex I, CI) and ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII), resulting in different assemblies (supercomplex SCI(1)III(2)IV(1) and megacomplex MCI(2)III(2)IV(2)).
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
messages: Membrane

244447:pde7a
gene id: 244447:pde7a
uniprot id: A0A3P8W9M2
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

244447:hdac2
gene id: 244447:hdac2
uniprot id: A0A3P8WPI0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone deacetylase family. HD Type 1 subfamily.
messages: Histone deacetylase that catalyzes the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.
messages: Nucleus

244447:LOC103380157
gene id: 244447:LOC103380157
uniprot id: A0A3P8V7K3
names: Similarity
messages: Belongs to the liprin family. Liprin-beta subfamily.

244447:ndc80
gene id: 244447:ndc80
uniprot id: A0A3P8V536
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.
messages: Belongs to the NDC80/HEC1 family.
messages: Component of the NDC80 complex.
messages: Nucleus
messages: kinetochore

244447:arl6ip5
gene id: 244447:arl6ip5
uniprot id: A0A3P8WNI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA1 family.
messages: Membrane

244447:LOC103388515
gene id: 244447:LOC103388515
uniprot id: A0A3P8V6B6
names: Similarity
messages: Belongs to the heat shock protein 70 family.

244447:LOC103396026
gene id: 244447:LOC103396026
uniprot id: A0A3P8WBU7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: dendrite

244447:fam160a1
gene id: 244447:fam160a1
uniprot id: A0A3P8UWN9
names: Similarity
messages: Belongs to the FHIP family.

244447:sfr1
gene id: 244447:sfr1
uniprot id: A0A3P8WFL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SFR1/MEI5 family.
messages: Nucleus

244447:LOC103389784
gene id: 244447:LOC103389784
uniprot id: A0A3P8W3Q4
names: Similarity
messages: Belongs to the carotenoid oxygenase family.

244447:lhx3
gene id: 244447:lhx3
uniprot id: A0A3P8WNH5
names: Subcellular Location Annotation
messages: Nucleus

244447:med10
gene id: 244447:med10
uniprot id: A0A3P8W0V8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 10 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

244447:uxs1
gene id: 244447:uxs1
uniprot id: A0A3P8UXH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily.
messages: Golgi stack membrane
messages: Membrane

244447:chpf
gene id: 244447:chpf
uniprot id: A0A3P8W2D4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chondroitin N-acetylgalactosaminyltransferase family.
messages: Golgi stack membrane
messages: Membrane

244447:LOC103393199
gene id: 244447:LOC103393199
uniprot id: A0A3P8WKH4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

244447:tcp11l2
gene id: 244447:tcp11l2
uniprot id: A0A3P8V6C4
names: Similarity
messages: Belongs to the TCP11 family.

244447:LOC103382261
gene id: 244447:LOC103382261
uniprot id: A0A3P8ULR2
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.

244447:lrrc42
gene id: 244447:lrrc42
uniprot id: A0A3P8W411
names: Similarity
messages: Belongs to the LRRC42 family.

244447:LOC103386590
gene id: 244447:LOC103386590
uniprot id: A0A3P8WJY5
uniprot id: A0A3P8WME4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein arginine deiminase family.
messages: Catalyzes the deimination of arginine residues of proteins.
messages: Cytoplasm

244447:mrps26
gene id: 244447:mrps26
uniprot id: A0A3P8W321
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mS26 family.
messages: Mitochondrion

244447:apoo
gene id: 244447:apoo
uniprot id: A0A3P8WFG5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the apolipoprotein O/MICOS complex subunit Mic27 family.
messages: Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.
messages: Component of the mitochondrial contact site and cristae organizing system (MICOS) complex.
messages: Mitochondrion inner membrane

244447:LOC103395641
gene id: 244447:LOC103395641
uniprot id: A0A3P8X569
names: Similarity
messages: Belongs to the serpin family.

244447:LOC103387254
gene id: 244447:LOC103387254
uniprot id: A0A3P8V5Y1
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

244447:gkap1
gene id: 244447:gkap1
uniprot id: A0A3P8W1F6
names: Similarity
messages: Belongs to the GKAP1 family.

244447:LOC103378480
gene id: 244447:LOC103378480
uniprot id: A0A3P8UUN1
names: Similarity
messages: Belongs to the CDC50/LEM3 family.

244447:lpar1
gene id: 244447:lpar1
uniprot id: A0A3P8WUY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Cell surface
messages: Endosome
messages: Membrane

244447:LOC103382757
gene id: 244447:LOC103382757
uniprot id: A0A3P8VJZ2
names: Subcellular Location Annotation
messages: Membrane

244447:LOC103383759
gene id: 244447:LOC103383759
uniprot id: A0A3P8V7Z0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
messages: Cell membrane
messages: Membrane

244447:LOC103397084
gene id: 244447:LOC103397084
uniprot id: A0A3P8VX75
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KISH family.
messages: Golgi apparatus membrane
messages: Involved in the early part of the secretory pathway.
messages: Membrane

244447:slc35a2
gene id: 244447:slc35a2
uniprot id: A0A3P8WNN9
uniprot id: A0A3P8WTY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide-sugar transporter family. SLC35A subfamily.
messages: Membrane

244447:LOC103397105
gene id: 244447:LOC103397105
uniprot id: A0A3P8VYD4
names: Similarity
messages: Belongs to the AAA ATPase family.

244447:ercc2
gene id: 244447:ercc2
uniprot id: A0A3P8V871
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the helicase family. RAD3/XPD subfamily.
messages: Nucleus

244447:LOC103396373
gene id: 244447:LOC103396373
uniprot id: A0A3P8VWH9
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. Alanine aminotransferase subfamily.
messages: Homodimer.

244447:LOC103377535
gene id: 244447:LOC103377535
uniprot id: A0A3P8UH21
names: Subcellular Location Annotation
messages: Nucleus

244447:LOC103384301
gene id: 244447:LOC103384301
uniprot id: A0A3P8WGC1
names: Similarity
messages: Belongs to the MS4A family.

244447:LOC103399855
gene id: 244447:LOC103399855
uniprot id: A0A3P8UTI3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Binds 2 magnesium ions per subunit. Is also active with manganese (in vitro).
messages: Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.
messages: Membrane

244447:dse
gene id: 244447:dse
uniprot id: A0A3P8WLK5
names: Similarity
messages: Belongs to the dermatan-sulfate isomerase family.

244447:LOC103395273
gene id: 244447:LOC103395273
uniprot id: A0A3P8W4S2
uniprot id: A0A3P8W7R1
names: Similarity
messages: Belongs to the JAKMIP family.

244447:lsm2
gene id: 244447:lsm2
uniprot id: A0A3P8UQ36
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP Sm proteins family.
messages: Binds specifically to the 3'-terminal U-tract of U6 snRNA.
messages: Nucleus

244447:LOC103377898
gene id: 244447:LOC103377898
uniprot id: A0A3P8V1W6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the kinesin light chain family.
messages: Kinesin is a microtubule-associated force-producing protein that play a role in organelle transport.
messages: Oligomeric complex composed of two heavy chains and two light chains.
messages: cytoskeleton

244447:arf1
gene id: 244447:arf1
uniprot id: A0A3P8VVB9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: GTP-binding protein involved in protein trafficking; modulates vesicle budding and uncoating within the Golgi apparatus.
messages: Golgi apparatus

244447:LOC103392072
gene id: 244447:LOC103392072
uniprot id: A0A3P8VWU7
names: Similarity
messages: Belongs to the NAD(P)H dehydrogenase (quinone) family.

244447:LOC103388201
gene id: 244447:LOC103388201
uniprot id: A0A3P8US75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Cell membrane
messages: Membrane

244447:LOC103399851
gene id: 244447:LOC103399851
uniprot id: A0A3P8UNN3
uniprot id: A0A3P8UT92
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatase and actin regulator family.
messages: Binds PPP1CA and actin.
messages: Cytoplasm
messages: Nucleus
messages: Synapse

244447:LOC103376874
gene id: 244447:LOC103376874
uniprot id: A0A3P8UKM6
names: Similarity
messages: Belongs to the YY transcription factor family.

244447:galnt3
gene id: 244447:galnt3
uniprot id: A0A3P8VG06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

244447:mpi
gene id: 244447:mpi
uniprot id: A0A3P8ULX3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 1 family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions.

244447:LOC103382986
gene id: 244447:LOC103382986
uniprot id: A0A3P8W5U4
names: Similarity
messages: Belongs to the SEC6 family.

244447:LOC103398298
gene id: 244447:LOC103398298
uniprot id: A0A3P8WJJ8
names: Similarity
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDC5/Polo subfamily.

244447:LOC103389987
gene id: 244447:LOC103389987
uniprot id: A0A3P8VZP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anion exchanger (TC 2.A.31) family.
messages: Membrane

244447:slc35b4
gene id: 244447:slc35b4
uniprot id: A0A3P8WBQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide-sugar transporter family. SLC35B subfamily.
messages: Membrane

244447:LOC103399857
gene id: 244447:LOC103399857
uniprot id: A0A3P8UTK3
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

244447:rflnb
gene id: 244447:rflnb
uniprot id: A0A3P8WLV9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Refilin family.
messages: Interacts with FLNA and FLNB.
messages: cytoskeleton

244447:irf4
gene id: 244447:irf4
uniprot id: A0A3P8VSE6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IRF family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

244447:LOC103390631
gene id: 244447:LOC103390631
uniprot id: A0A3P8UPZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Endoplasmic reticulum membrane
messages: Membrane

244447:LOC103399856
gene id: 244447:LOC103399856
uniprot id: A0A3P8UMG1
names: Caution
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Binds equally well IGF1 and IGF2.
messages: IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. Promotes cell migration.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

244447:tmem234
gene id: 244447:tmem234
uniprot id: A0A3P8UM97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM234 family.
messages: Membrane

244447:rft1
gene id: 244447:rft1
uniprot id: A0A3P8UNC0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RFT1 family.
messages: May be involved in N-linked oligosaccharide assembly.
messages: Membrane

244447:arhgef6
gene id: 244447:arhgef6
uniprot id: A0A3P8V2G3
names: Subcellular Location Annotation
messages: lamellipodium

244447:nox4
gene id: 244447:nox4
uniprot id: A0A3P8WRR4
names: Subcellular Location Annotation
messages: Membrane

244447:LOC103385429
gene id: 244447:LOC103385429
uniprot id: A0A3P8X023
names: Similarity
messages: Belongs to the dysbindin family.

244447:LOC103380823
gene id: 244447:LOC103380823
uniprot id: A0A3P8WZ27
names: Similarity
messages: Belongs to the peptidase C1 family.

244447:LOC103380283
gene id: 244447:LOC103380283
uniprot id: A0A3P8VGK4
uniprot id: A0A3P8VGM0
names: Similarity
messages: Belongs to the SEC2 family.

244447:LOC103397768
gene id: 244447:LOC103397768
uniprot id: A0A3P8X1R6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dynein light chain family.
messages: cytoskeleton

244447:dnajc22
gene id: 244447:dnajc22
uniprot id: A0A3P8V6L3
names: Function
names: Subcellular Location Annotation
messages: May function as a co-chaperone.
messages: Membrane

244447:LOC103389639
gene id: 244447:LOC103389639
uniprot id: A0A3P8VE60
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essential roles within the cell by associating with different regulatory particles. Associated with two 19S regulatory particles, forms the 26S proteasome and thus participates in the ATP-dependent degradation of ubiquitinated proteins. The 26S proteasome plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins that could impair cellular functions, and by removing proteins whose functions are no longer required. Associated with the PA200 or PA28, the 20S proteasome mediates ubiquitin-independent protein degradation. This type of proteolysis is required in several pathways including spermatogenesis (20S-PA200 complex) or generation of a subset of MHC class I-presented antigenic peptides (20S-PA28 complex). Within the 20S core complex, PSMB7 displays a trypsin-like activity.
messages: Component of the proteasome complex.
messages: Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
messages: Cytoplasm
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits. The 20S proteasome core is a barrel-shaped complex made of 28 subunits that are arranged in four stacked rings. The two outer rings are each formed by seven alpha subunits, and the two inner rings are formed by seven beta subunits. The proteolytic activity is exerted by three beta-subunits PSMB5, PSMB6 and PSMB7.
messages: The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. This subunit is involved in antigen processing to generate class I binding peptides.

244447:pmm1
gene id: 244447:pmm1
uniprot id: A0A3P8VDH6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic PMM family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions.

244447:LOC103389894
gene id: 244447:LOC103389894
uniprot id: A0A3P8VWZ0
names: Similarity
messages: Belongs to the S-100 family.

244447:LOC103384501
gene id: 244447:LOC103384501
uniprot id: A0A3P8WV38
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

244447:plpp1
gene id: 244447:plpp1
uniprot id: A0A3P8UFC5
uniprot id: A0A3P8UFD0
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Cell membrane
messages: Membrane
messages: Membrane raft
messages: caveola

244447:pax1
gene id: 244447:pax1
uniprot id: A0A3P8U9S0
names: Subcellular Location Annotation
messages: Nucleus

244447:ogt
gene id: 244447:ogt
uniprot id: A0A3P8W744
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 41 family. O-GlcNAc transferase subfamily.
messages: Cell projection
messages: Mitochondrion membrane

244447:LOC103396627
gene id: 244447:LOC103396627
uniprot id: A0A3P8X2E1
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

244447:LOC103386623
gene id: 244447:LOC103386623
uniprot id: A0A3P8WKZ5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the plexin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

244447:tpmt
gene id: 244447:tpmt
uniprot id: A0A3P8VNT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TPMT family.
messages: Cytoplasm

244447:anapc10
gene id: 244447:anapc10
uniprot id: A0A3P8V485
names: Function
names: Similarity
messages: Belongs to the APC10 family.
messages: Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle.

244447:LOC103399887
gene id: 244447:LOC103399887
uniprot id: A0A3P8UKW3
names: Similarity
messages: Belongs to the BRINP family.

244447:LOC103392287
gene id: 244447:LOC103392287
uniprot id: A0A3P8W8L0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RAMP4 family.
messages: Endoplasmic reticulum membrane
messages: May interact with target proteins during translocation into the lumen of the endoplasmic reticulum. May protect unfolded target proteins against degradation and facilitate correct glycosylation.
messages: Membrane

244447:cpne8
gene id: 244447:cpne8
uniprot id: A0A3P8W4D5
names: Similarity
messages: Belongs to the copine family.

244447:gtf2f1
gene id: 244447:gtf2f1
uniprot id: A0A3P8W5Q0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFIIF alpha subunit family.
messages: Nucleus
messages: TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation.

244447:LOC103387765
gene id: 244447:LOC103387765
uniprot id: A0A3P8WRX6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the lunapark family.
messages: Endoplasmic reticulum membrane
messages: Homodimer; homodimerization requires the C4-type zinc finger motif and decreases during mitosis in a phosphorylation-dependent manner.
messages: Plays a role in determining ER morphology.
messages: The C4-type zinc finger motif is necessary both for its ER three-way tubular junction localization and formation.

244447:LOC103382999
gene id: 244447:LOC103382999
uniprot id: A0A3P8WGF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ARMET family.
messages: Secreted

244447:hmgcl
gene id: 244447:hmgcl
uniprot id: A0A3P8UC83
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HMG-CoA lyase family.
messages: Homodimer; disulfide-linked. Can also form homotetramers.
messages: Mitochondrial 3-hydroxymethyl-3-methylglutaryl-CoA lyase that catalyzes a cation-dependent cleavage of (S)-3-hydroxy-3-methylglutaryl-CoA into acetyl-CoA and acetoacetate, a key step in ketogenesis. Terminal step in leucine catabolism. Ketone bodies (beta-hydroxybutyrate, acetoacetate and acetone) are essential as an alternative source of energy to glucose, as lipid precursors and as regulators of metabolism.

244447:trip13
gene id: 244447:trip13
uniprot id: A0A3P8UUS9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family. PCH2 subfamily.
messages: Nucleus
messages: Plays a key role in chromosome recombination and chromosome structure development during meiosis. Required at early steps in meiotic recombination that leads to non-crossovers pathways. Also needed for efficient completion of homologous synapsis by influencing crossover distribution along the chromosomes affecting both crossovers and non-crossovers pathways.

244447:uggt1
gene id: 244447:uggt1
uniprot id: A0A3P8UZ95
uniprot id: A0A3P8V2X4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 8 family.
messages: Endoplasmic reticulum lumen

244447:LOC103394709
gene id: 244447:LOC103394709
uniprot id: A0A3P8VSJ7
names: Similarity
messages: Belongs to the stathmin family.

244447:med30
gene id: 244447:med30
uniprot id: A0A3P8VX05
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mediator complex subunit 30 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Nucleus

244447:LOC103377699
gene id: 244447:LOC103377699
uniprot id: A0A3P8UXU8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: gap junction

244447:LOC103381560
gene id: 244447:LOC103381560
uniprot id: A0A3P8V972
uniprot id: A0A3P8VF80
uniprot id: A0A3P8VHE1
names: Similarity
messages: Belongs to the dpy-30 family.

244447:eef1akmt1
gene id: 244447:eef1akmt1
uniprot id: A0A3P8VNJ0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. EFM5 family.
messages: Cytoplasm
messages: Protein-lysine methyltransferase that selectively catalyzes the trimethylation of EEF1A at 'Lys-79'.
messages: Was originally thought to be an N(6)-adenine-specific DNA methyltransferase based on primary sequence and predicted secondary structure.

244447:pde10a
gene id: 244447:pde10a
uniprot id: A0A3P8VUM0
uniprot id: A0A3P8VX32
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

244447:LOC103388881
gene id: 244447:LOC103388881
uniprot id: A0A3P8VYF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STT3 family.
messages: Membrane

244447:rpf1
gene id: 244447:rpf1
uniprot id: A0A3P8VJ05
names: Subcellular Location Annotation
messages: nucleolus

244447:atic
gene id: 244447:atic
uniprot id: A0A3P8UHQ1
names: Similarity
messages: Belongs to the PurH family.

244447:dennd5a
gene id: 244447:dennd5a
uniprot id: A0A3P8VNM5
uniprot id: A0A3P8VNR3
names: Caution
names: Similarity
messages: Belongs to the RAB6IP1 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

244447:triqk
gene id: 244447:triqk
uniprot id: A0A3P8WVH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRIQK family.
messages: Endoplasmic reticulum membrane
messages: Membrane

244447:LOC103390422
gene id: 244447:LOC103390422
uniprot id: A0A3P8UGH0
names: Subcellular Location Annotation
messages: nucleoplasm

244447:LOC103377312
gene id: 244447:LOC103377312
uniprot id: A0A3P8WPW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calycin superfamily. Lipocalin family.
messages: Secreted

244447:pet117
gene id: 244447:pet117
uniprot id: A0A3P8UMC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PET117 family.
messages: Mitochondrion

244447:LOC103379959
gene id: 244447:LOC103379959
uniprot id: A0A3P8US35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM168 family.
messages: Membrane

244447:LOC103395611
gene id: 244447:LOC103395611
uniprot id: A0A3P8WXQ9
names: Similarity
messages: Belongs to the SAP30 family.

244447:LOC103377953
gene id: 244447:LOC103377953
uniprot id: A0A3P8V892
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPSB family.
messages: Cytoplasm

244447:ugdh
gene id: 244447:ugdh
uniprot id: A0A3P8V504
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.
messages: Homohexamer.
messages: Involved in the biosynthesis of glycosaminoglycans; hyaluronan, chondroitin sulfate, and heparan sulfate.

244447:LOC103395865
gene id: 244447:LOC103395865
uniprot id: A0A3P8VVJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

244447:tiparp
gene id: 244447:tiparp
uniprot id: A0A3P8UJY3
names: Similarity
messages: Belongs to the ARTD/PARP family.

244447:LOC103379542
gene id: 244447:LOC103379542
uniprot id: A0A3P8X0C6
names: Cofactor
names: Similarity
messages: Belongs to the transglutaminase superfamily. Transglutaminase family.
messages: Binds 1 Ca(2+) ion per subunit.

244447:LOC103385220
gene id: 244447:LOC103385220
uniprot id: A0A3P8VR99
names: Similarity
messages: Belongs to the PMEL/NMB family.

244447:LOC103382807
gene id: 244447:LOC103382807
uniprot id: A0A3P8VJ11
names: Subcellular Location Annotation
messages: Membrane

244447:tmeff2
gene id: 244447:tmeff2
uniprot id: A0A3P8WM95
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

244447:hexb
gene id: 244447:hexb
uniprot id: A0A3P8W4J4
uniprot id: A0A3P8W7M3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 20 family.
messages: Lysosome

244447:LOC103388952
gene id: 244447:LOC103388952
uniprot id: A0A3P8W653
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/PBX homeobox family.
messages: Nucleus

244447:LOC103396007
gene id: 244447:LOC103396007
uniprot id: A0A3P8WBL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paired homeobox family.
messages: Nucleus

244447:LOC103386545
gene id: 244447:LOC103386545
uniprot id: A0A3P8WE82
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase.

244447:nutf2
gene id: 244447:nutf2
uniprot id: A0A3P8W369
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Has a role in nuclear-cytoplasmic transport of proteins and mRNAs.
messages: Nucleus

244447:LOC103392977
gene id: 244447:LOC103392977
uniprot id: A0A3P8W510
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 3 family.
messages: Transfers the glycosyl residue from UDP-Glc to the non-reducing end of alpha-1,4-glucan.

244447:LOC103383857
gene id: 244447:LOC103383857
uniprot id: A0A3P8VIZ8
names: Similarity
messages: Belongs to the TTC39 family.

244447:LOC103377373
gene id: 244447:LOC103377373
uniprot id: A0A3P8WUW0
names: Similarity
messages: Belongs to the small GTPase superfamily. Ras family.

244447:LOC103379287
gene id: 244447:LOC103379287
uniprot id: A0A3P8VNF2
names: Similarity
messages: Belongs to the calcitonin family.

244447:gpm6b
gene id: 244447:gpm6b
uniprot id: A0A3P8UYL1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the myelin proteolipid protein family.
messages: Membrane

244447:cpq
gene id: 244447:cpq
uniprot id: A0A3P8UXC1
names: Subcellular Location Annotation
names: Subunit
messages: Endoplasmic reticulum
messages: Golgi apparatus
messages: Homodimer. The monomeric form is inactive while the homodimer is active.
messages: Lysosome
messages: Secreted

244447:LOC103377559
gene id: 244447:LOC103377559
uniprot id: A0A3P8UPA7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Endosome membrane
messages: Membrane

244447:LOC103395217
gene id: 244447:LOC103395217
uniprot id: A0A3P8VZZ2
names: Similarity
names: Subunit
messages: Belongs to the ENDOU family.
messages: Monomer.

244447:pou6f2
gene id: 244447:pou6f2
uniprot id: A0A3P8X095
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POU transcription factor family.
messages: Nucleus

244447:ube3a
gene id: 244447:ube3a
uniprot id: A0A3P8V1U0
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and transfers it to its substrates.
messages: Nucleus

244447:rab3gap1
gene id: 244447:rab3gap1
uniprot id: A0A3P8WIL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Rab3-GAP catalytic subunit family.
messages: Cytoplasm

244447:spin1
gene id: 244447:spin1
uniprot id: A0A3P8USN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPIN/STSY family.
messages: Nucleus

244447:hoxc9
gene id: 244447:hoxc9
uniprot id: A0A3P8VD66
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

244447:LOC103386293
gene id: 244447:LOC103386293
uniprot id: A0A3P8VCG7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rho family. CDC42 subfamily.
messages: Cell membrane
messages: Membrane
messages: Midbody
messages: Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state.

244447:LOC103398297
gene id: 244447:LOC103398297
uniprot id: A0A3P8WM59
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Cell membrane
messages: Protein transport. Probably involved in vesicular traffic.

244447:rps21
gene id: 244447:rps21
uniprot id: A0A3P8VCL2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS21 family.
messages: Component of the 40S small ribosomal subunit.
messages: Endoplasmic reticulum
messages: Rough endoplasmic reticulum
messages: cytosol

244447:LOC103388402
gene id: 244447:LOC103388402
uniprot id: A0A3P8V5T3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

244447:LOC103391372
gene id: 244447:LOC103391372
uniprot id: A0A3P8X031
names: Similarity
messages: Belongs to the actin family.

244447:LOC103393096
gene id: 244447:LOC103393096
uniprot id: A0A3P8W9B3
names: Similarity
messages: Belongs to the FAM20 family.

244447:psma5
gene id: 244447:psma5
uniprot id: A0A3P8V2H2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Cytoplasm
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.

244447:ucp1
gene id: 244447:ucp1
uniprot id: A0A3P8X515
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

244447:LOC103382598
gene id: 244447:LOC103382598
uniprot id: A0A3P8W6J5
names: Similarity
messages: Belongs to the phosphatase 2A regulatory subunit B56 family.

244447:LOC103384687
gene id: 244447:LOC103384687
uniprot id: A0A3P8UWH3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase IV family.
messages: Component of the cytochrome c oxidase (complex IV, CIV), a multisubunit enzyme composed of 14 subunits.
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.
messages: Membrane
messages: Mitochondrion inner membrane

244447:tbcc
gene id: 244447:tbcc
uniprot id: A0A3P8W3C6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TBCC family.
messages: Cytoplasm
messages: Supercomplex made of cofactors A to E. Cofactors A and D function by capturing and stabilizing tubulin in a quasi-native conformation. Cofactor E binds to the cofactor D-tubulin complex; interaction with cofactor C then causes the release of tubulin polypeptides that are committed to the native state.

244447:psd2
gene id: 244447:psd2
uniprot id: A0A3P8WMA8
names: Subcellular Location Annotation
messages: ruffle membrane

244447:taf5
gene id: 244447:taf5
uniprot id: A0A3P8VTU5
names: Similarity
messages: Belongs to the WD repeat TAF5 family.

244447:LOC103390156
gene id: 244447:LOC103390156
uniprot id: A0A3P8WIJ4
names: Similarity
messages: Belongs to the beta-catenin family.

244447:LOC103392680
gene id: 244447:LOC103392680
uniprot id: A0A3P8X3P7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HARBI1 family.
messages: Nucleus

244447:LOC103377883
gene id: 244447:LOC103377883
uniprot id: A0A3P8V543
names: Similarity
messages: Belongs to the phospholipase D family.

244447:LOC103397799
gene id: 244447:LOC103397799
uniprot id: A0A3P8WY80
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

244447:esam
gene id: 244447:esam
uniprot id: A0A3P8WLJ0
names: Subcellular Location Annotation
messages: Membrane

244447:LOC103377633
gene id: 244447:LOC103377633
uniprot id: A0A3P8ULQ9
names: Subcellular Location Annotation
messages: Membrane

244447:tecr
gene id: 244447:tecr
uniprot id: A0A3P8VTI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the steroid 5-alpha reductase family.
messages: Endoplasmic reticulum membrane
messages: Membrane

244447:LOC103380118
gene id: 244447:LOC103380118
uniprot id: A0A3P8UU31
names: Subcellular Location Annotation
messages: Nucleus

244447:LOC103383966
gene id: 244447:LOC103383966
uniprot id: A0A3P8VF39
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.

244447:oprl1
gene id: 244447:oprl1
uniprot id: A0A3P8VCD7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

244447:LOC103383656
gene id: 244447:LOC103383656
uniprot id: A0A3P8UY40
names: Similarity
messages: Belongs to the DEAD box helicase family. DEAH subfamily. DDX15/PRP43 sub-subfamily.

244447:pop5
gene id: 244447:pop5
uniprot id: A0A3P8VEU4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic/archaeal RNase P protein component 2 family.
messages: Component of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.
messages: nucleolus

244447:LOC103395266
gene id: 244447:LOC103395266
uniprot id: A0A3P8W6Y2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

244447:dcstamp
gene id: 244447:dcstamp
uniprot id: A0A3P8W4C0
names: Subcellular Location Annotation
messages: Membrane

244447:LOC103387925
gene id: 244447:LOC103387925
uniprot id: A0A3P8X3J2
names: Similarity
messages: Belongs to the glycosyl hydrolase 47 family.

244447:LOC103391326
gene id: 244447:LOC103391326
uniprot id: A0A3P8WLS1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM182 family.
messages: Cell membrane
messages: Membrane

244447:LOC103376725
gene id: 244447:LOC103376725
uniprot id: A0A3P8UGG2
names: Subcellular Location Annotation
messages: Nucleus

244447:fam20b
gene id: 244447:fam20b
uniprot id: A0A3P8VBW2
names: Similarity
messages: Belongs to the FAM20 family.

244447:ccdc25
gene id: 244447:ccdc25
uniprot id: A0A3P8UXQ1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CCDC25 family.
messages: Cell membrane
messages: Endomembrane system
messages: Interacts (via cytoplasmic region) with ILK.

244447:LOC103389823
gene id: 244447:LOC103389823
uniprot id: A0A3P8VPF2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TGF-beta family.
messages: Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins.
messages: Secreted

244447:kif3b
gene id: 244447:kif3b
uniprot id: A0A3P8V021
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

244447:LOC103397136
gene id: 244447:LOC103397136
uniprot id: A0A3P8VXF4
names: Similarity
messages: Belongs to the serpin family.

244447:LOC103379083
gene id: 244447:LOC103379083
uniprot id: A0A3P8VWY6
uniprot id: A0A3P8W5B9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dwarfin/SMAD family.
messages: Cytoplasm
messages: Nucleus

244447:glipr1
gene id: 244447:glipr1
uniprot id: A0A3P8WNR5
names: Similarity
messages: Belongs to the CRISP family.

244447:mrps33
gene id: 244447:mrps33
uniprot id: A0A3P8WIG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mS33 family.
messages: Mitochondrion

244447:tm6sf2
gene id: 244447:tm6sf2
uniprot id: A0A3P8W6E8
names: Subcellular Location Annotation
messages: Membrane

244447:stxbp3
gene id: 244447:stxbp3
uniprot id: A0A3P8WSD3
names: Similarity
messages: Belongs to the STXBP/unc-18/SEC1 family.

244447:LOC103377999
gene id: 244447:LOC103377999
uniprot id: A0A3P8V7M3
names: Similarity
messages: Belongs to the FRAS1 family.

244447:LOC103396408
gene id: 244447:LOC103396408
uniprot id: A0A3P8W4U3
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family. PDE1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

244447:ace
gene id: 244447:ace
uniprot id: A0A3P8X132
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M2 family.
messages: Binds 2 Zn(2+) ions per subunit.

244447:fbxo32
gene id: 244447:fbxo32
uniprot id: A0A3P8VM65
names: Subcellular Location Annotation
messages: Nucleus

244447:LOC103384161
gene id: 244447:LOC103384161
uniprot id: A0A3P8W6Q1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Membrane

244447:LOC103395318
gene id: 244447:LOC103395318
uniprot id: A0A3P8W9K1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

244447:c8g
gene id: 244447:c8g
uniprot id: A0A3P8VIA3
names: Similarity
messages: Belongs to the calycin superfamily. Lipocalin family.

244447:upf3a
gene id: 244447:upf3a
uniprot id: A0A3P8V481
names: Similarity
messages: Belongs to the RENT3 family.

244447:LOC103397666
gene id: 244447:LOC103397666
uniprot id: A0A3P8WK45
names: Similarity
messages: Belongs to the vasopressin/oxytocin family.

244447:phf8
gene id: 244447:phf8
uniprot id: A0A3P8UNA7
names: Similarity
messages: Belongs to the JHDM1 histone demethylase family. JHDM1D subfamily.

244447:sh2b2
gene id: 244447:sh2b2
uniprot id: A0A3P8WR53
names: Similarity
messages: Belongs to the SH2B adapter family.

244447:polr2i
gene id: 244447:polr2i
uniprot id: A0A3P8URP7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.
messages: Component of the RNA polymerase II (Pol II) complex consisting of 12 subunits.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: nucleolus

244447:LOC103386181
gene id: 244447:LOC103386181
uniprot id: A0A3P8UYA2
names: Subcellular Location Annotation
messages: cytoskeleton

244447:LOC103385608
gene id: 244447:LOC103385608
uniprot id: A0A3P8X1Q5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acid desaturase CarF family.
messages: Membrane

244447:pigf
gene id: 244447:pigf
uniprot id: A0A3P8VR90
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

244447:entpd6
gene id: 244447:entpd6
uniprot id: A0A3P8UMC2
names: Similarity
messages: Belongs to the GDA1/CD39 NTPase family.

244447:LOC103383828
gene id: 244447:LOC103383828
uniprot id: A0A3P8VIA0
names: Similarity
messages: Belongs to the WD repeat coronin family.

244447:pkig
gene id: 244447:pkig
uniprot id: A0A3P8VIT2
names: Function
names: Similarity
messages: Belongs to the PKI family.
messages: Extremely potent competitive inhibitor of cAMP-dependent protein kinase activity, this protein interacts with the catalytic subunit of the enzyme after the cAMP-induced dissociation of its regulatory chains.

244447:hmx3
gene id: 244447:hmx3
uniprot id: A0A3P8WL12
names: Subcellular Location Annotation
messages: Nucleus

244447:LOC103378375
gene id: 244447:LOC103378375
uniprot id: A0A3P8WI11
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 13 family.
messages: Component of the Mediator complex, a coactivator involved in regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

244447:LOC103394229
gene id: 244447:LOC103394229
uniprot id: A0A3P8W7E5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

244447:pik3r1
gene id: 244447:pik3r1
uniprot id: A0A3P8W5A2
uniprot id: A0A3P8WAW4
names: Similarity
messages: Belongs to the PI3K p85 subunit family.

244447:LOC103391061
gene id: 244447:LOC103391061
uniprot id: A0A3P8W4Y1
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZP domain family. ZPC subfamily.
messages: Cell membrane
messages: Component of the zona pellucida, an extracellular matrix surrounding oocytes which mediates sperm binding, induction of the acrosome reaction and prevents post-fertilization polyspermy. The zona pellucida is composed of 3 to 4 glycoproteins, ZP1, ZP2, ZP3, and ZP4. ZP3 is essential for sperm binding and zona matrix formation.
messages: Proteolytically cleaved before the transmembrane segment to yield the secreted ectodomain incorporated in the zona pellucida.
messages: The ZP domain is involved in the polymerization of the ZP proteins to form the zona pellucida.
messages: Zona pellucida

244447:LOC103378503
gene id: 244447:LOC103378503
uniprot id: A0A3P8WNQ6
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

244447:sema3b
gene id: 244447:sema3b
uniprot id: A0A3P8V8V9
names: Caution
names: Similarity
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

244447:slc25a4
gene id: 244447:slc25a4
uniprot id: A0A3P8UYL0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Catalyzes the exchange of ADP and ATP across the membrane.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Monomer.

244447:LOC103383048
gene id: 244447:LOC103383048
uniprot id: A0A3P8WNQ0
names: Similarity
messages: Belongs to the ric-3 family.

244447:LOC103378615
gene id: 244447:LOC103378615
uniprot id: A0A3P8UJH7
names: Similarity
messages: Belongs to the actin family.

244447:crbn
gene id: 244447:crbn
uniprot id: A0A3P8USH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CRBN family.
messages: Nucleus

244447:LOC103393384
gene id: 244447:LOC103393384
uniprot id: A0A3P8VAQ5
names: Function
names: Similarity
messages: Belongs to the rod/cone cGMP-PDE gamma subunit family.
messages: Participates in processes of transmission and amplification of the visual signal. cGMP-PDEs are the effector molecules in G-protein-mediated phototransduction in vertebrate rods and cones.

244447:LOC103380193
gene id: 244447:LOC103380193
uniprot id: A0A3P8V2P8
names: Similarity
messages: Belongs to the TMEM178 family.

244447:fgfr1op2
gene id: 244447:fgfr1op2
uniprot id: A0A3P8WL53
names: Similarity
messages: Belongs to the SIKE family.

244447:ptp4a1
gene id: 244447:ptp4a1
uniprot id: A0A3P8WXA0
names: Subcellular Location Annotation
messages: Early endosome
messages: Endosome

244447:jak1
gene id: 244447:jak1
uniprot id: A0A3P8WTB1
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. JAK subfamily.

244447:LOC103398072
gene id: 244447:LOC103398072
uniprot id: A0A3P8VST0
names: Subcellular Location Annotation
messages: Nucleus

244447:tsn
gene id: 244447:tsn
uniprot id: A0A3P8V3B9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the translin family.
messages: DNA-binding protein that specifically recognizes consensus sequences at the breakpoint junctions in chromosomal translocations, mostly involving immunoglobulin (Ig)/T-cell receptor gene segments. Seems to recognize single-stranded DNA ends generated by staggered breaks occurring at recombination hot spots.
messages: Exhibits both single-stranded and double-stranded endoribonuclease activity. May act as an activator of RNA-induced silencing complex (RISC) by facilitating endonucleolytic cleavage of the siRNA passenger strand.
messages: Nucleus
messages: Ring-shaped heterooctamer of six TSN and two TSNAX subunits, DNA/RNA binding occurs inside the ring.

244447:plpbp
gene id: 244447:plpbp
uniprot id: A0A3P8UTV3
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which may be involved in intracellular homeostatic regulation of pyridoxal 5'-phosphate (PLP), the active form of vitamin B6.

244447:pgp
gene id: 244447:pgp
uniprot id: A0A3P8UL51
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

244447:LOC103388528
gene id: 244447:LOC103388528
uniprot id: A0A3P8V868
names: Subcellular Location Annotation
messages: extracellular space

244447:LOC103388432
gene id: 244447:LOC103388432
uniprot id: A0A3P8V4Q9
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

244447:faxc
gene id: 244447:faxc
uniprot id: A0A3P8VDJ9
names: Similarity
messages: Belongs to the FAX family.

244447:rps6ka3
gene id: 244447:rps6ka3
uniprot id: A0A3P8WBT3
uniprot id: A0A3P8WBX1
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.

244447:LOC103395976
gene id: 244447:LOC103395976
uniprot id: A0A3P8WA50
uniprot id: A0A3P8WFG2
names: Domain
names: Similarity
messages: Belongs to the CAMSAP1 family.
messages: The CKK domain binds microtubules.

244447:pde11a
gene id: 244447:pde11a
uniprot id: A0A3P8UW50
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

244447:LOC103380480
gene id: 244447:LOC103380480
uniprot id: A0A3P8VXU1
names: Subcellular Location Annotation
messages: Membrane

244447:LOC103391154
gene id: 244447:LOC103391154
uniprot id: A0A3P8W6W6
uniprot id: A0A3P8W9N2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

244447:LOC103390731
gene id: 244447:LOC103390731
uniprot id: A0A3P8V495
names: Subcellular Location Annotation
messages: cytoskeleton

244447:gpr6
gene id: 244447:gpr6
uniprot id: A0A3P8X0D5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

244447:ndrg3
gene id: 244447:ndrg3
uniprot id: A0A3P8VNC8
uniprot id: A0A3P8VQM3
names: Similarity
messages: Belongs to the NDRG family.

244447:cdc37l1
gene id: 244447:cdc37l1
uniprot id: A0A3P8UL91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDC37 family.
messages: Cytoplasm

244447:gk
gene id: 244447:gk
uniprot id: A0A3P8V0H1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FGGY kinase family.
messages: Cytoplasm

244447:LOC103385110
gene id: 244447:LOC103385110
uniprot id: A0A3P8VGX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Nucleus

244447:mboat7
gene id: 244447:mboat7
uniprot id: A0A3P8WXW6
names: Subcellular Location Annotation
messages: Membrane

244447:LOC103389353
gene id: 244447:LOC103389353
uniprot id: A0A3P8UJ87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCF/LEF family.
messages: Nucleus

244447:ovol1
gene id: 244447:ovol1
uniprot id: A0A3P8UHE1
names: Subcellular Location Annotation
messages: Nucleus

244447:LOC103385495
gene id: 244447:LOC103385495
uniprot id: A0A3P8X2Z5
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Nucleus

244447:LOC103387209
gene id: 244447:LOC103387209
uniprot id: A0A3P8UZB5
names: Subcellular Location Annotation
messages: Secreted

244447:dapk2
gene id: 244447:dapk2
uniprot id: A0A3P8USJ8
names: Similarity
messages: Belongs to the protein kinase superfamily.

244447:trmt2a
gene id: 244447:trmt2a
uniprot id: A0A3P8VUN2
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

244447:LOC103388617
gene id: 244447:LOC103388617
uniprot id: A0A3P8VSP3
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

244447:LOC103378932
gene id: 244447:LOC103378932
uniprot id: A0A3P8UTI2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for ghrelin, coupled to G-alpha-11 proteins. Stimulates growth hormone secretion. Binds also other growth hormone releasing peptides (GHRP) (e.g. Met-enkephalin and GHRP-6) as well as non-peptide, low molecular weight secretagogues (e.g. L-692,429, MK-0677, adenosine).

244447:LOC103390988
gene id: 244447:LOC103390988
uniprot id: A0A3P8VP71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCR4/nocturin family.
messages: Cytoplasm
messages: Nucleus

244447:LOC103387007
gene id: 244447:LOC103387007
uniprot id: A0A3P8ULM3
names: Similarity
messages: Belongs to the cytochrome P450 family.

244447:LOC103390155
gene id: 244447:LOC103390155
uniprot id: A0A3P8WLF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dwarfin/SMAD family.
messages: Cytoplasm
messages: Nucleus

244447:casp6
gene id: 244447:casp6
uniprot id: A0A3P8VLW6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase C14A family.
messages: Cytoplasm
messages: Heterotetramer that consists of two anti-parallel arranged heterodimers, each one formed by a 18 kDa (Caspase-6 subunit p18) and a 11 kDa (Caspase-6 subunit p11) subunit.
messages: Nucleus

244447:prkar2a
gene id: 244447:prkar2a
uniprot id: A0A3P8V0R0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cAMP-dependent kinase regulatory chain family.
messages: Cell membrane
messages: Membrane

244447:btg1
gene id: 244447:btg1
uniprot id: A0A3P8V9J0
names: Function
names: Similarity
messages: Anti-proliferative protein.
messages: Belongs to the BTG family.

244447:LOC103386083
gene id: 244447:LOC103386083
uniprot id: A0A3P8UUX0
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MNB/DYRK subfamily.

244447:efnb2
gene id: 244447:efnb2
uniprot id: A0A3P8WC84
names: Caution
names: Similarity
messages: Belongs to the ephrin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

244447:LOC103388489
gene id: 244447:LOC103388489
uniprot id: A0A3P8VC69
names: Function
names: Similarity
names: Subunit
messages: Belongs to the casein kinase 2 subunit beta family.
messages: Regulatory subunit of casein kinase II/CK2. As part of the kinase complex regulates the basal catalytic activity of the alpha subunit a constitutively active serine/threonine-protein kinase that phosphorylates a large number of substrates containing acidic residues C-terminal to the phosphorylated serine or threonine. Participates in Wnt signaling.
messages: Tetramer of two alpha and two beta subunits.

244447:LOC103385434
gene id: 244447:LOC103385434
uniprot id: A0A0U1T4U3
names: Similarity
messages: Belongs to the TGF-beta family.

244447:mzt1
gene id: 244447:mzt1
uniprot id: A0A3P8UQJ0
names: Function
names: Similarity
messages: Belongs to the MOZART1 family.
messages: Required for gamma-tubulin complex recruitment to the centrosome.

244447:LOC103389439
gene id: 244447:LOC103389439
uniprot id: B3VCB7
names: Similarity
messages: Belongs to the cytochrome P450 family.

244447:LOC103377436
gene id: 244447:LOC103377436
uniprot id: A0A3P8UI88
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane
messages: Membrane

244447:LOC103396312
gene id: 244447:LOC103396312
uniprot id: A0A3P8VRN2
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. cAMP subfamily.

244447:galnt2
gene id: 244447:galnt2
uniprot id: A0A3P8UEX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

244447:fgf7
gene id: 244447:fgf7
uniprot id: A0A3P8W060
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

244447:tulp4
gene id: 244447:tulp4
uniprot id: A0A3P8WM36
names: Similarity
messages: Belongs to the TUB family.

244447:tbxt
gene id: 244447:tbxt
uniprot id: A0A3P8W332
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

244447:LOC103388839
gene id: 244447:LOC103388839
uniprot id: A0A3P8W0B5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 13 family.
messages: Golgi apparatus membrane
messages: Initiates complex N-linked carbohydrate formation. Essential for the conversion of high-mannose to hybrid and complex N-glycans.
messages: Membrane
messages: The cofactor is mostly bound to the substrate.

244447:creb3l2
gene id: 244447:creb3l2
uniprot id: A0A3P8V1E9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bZIP family. ATF subfamily.
messages: Binds DNA as a dimer.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Nucleus

244447:grn
gene id: 244447:grn
uniprot id: A0A3P8VL47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the granulin family.
messages: Secreted

244447:LOC103381269
gene id: 244447:LOC103381269
uniprot id: A0A3P8V1V1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sauvagine/corticotropin-releasing factor/urotensin I family.
messages: Secreted

244447:meox1
gene id: 244447:meox1
uniprot id: A0A3P8WGP0
names: Subcellular Location Annotation
messages: Nucleus

244447:prdm1
gene id: 244447:prdm1
uniprot id: A0A3P8VRM4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class V-like SAM-binding methyltransferase superfamily.
messages: Cytoplasm
messages: Interacts with PRMT5. Interacts with FBXO10. Interacts with FBXO11.
messages: Nucleus
messages: Transcription factor that mediates a transcriptional program in various innate and adaptive immune tissue-resident lymphocyte T cell types such as tissue-resident memory T (Trm), natural killer (trNK) and natural killer T (NKT) cells and negatively regulates gene expression of proteins that promote the egress of tissue-resident T-cell populations from non-lymphoid organs. Plays a role in the development, retention and long-term establishment of adaptive and innate tissue-resident lymphocyte T cell types in non-lymphoid organs, such as the skin and gut, but also in other nonbarrier tissues like liver and kidney, and therefore may provide immediate immunological protection against reactivating infections or viral reinfection. Binds specifically to the PRDI element in the promoter of the beta-interferon gene. Drives the maturation of B-lymphocytes into Ig secreting cells. Associates with the transcriptional repressor ZNF683 to chromatin at gene promoter regions.

244447:jam2
gene id: 244447:jam2
uniprot id: A0A3P8VUC9
names: Subcellular Location Annotation
messages: Membrane

244447:LOC103396929
gene id: 244447:LOC103396929
uniprot id: A0A3P8VI67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Musashi family.
messages: Cytoplasm

244447:LOC103385600
gene id: 244447:LOC103385600
uniprot id: A0A3P8X1S0
names: Similarity
messages: Belongs to the OSBP family.

244447:LOC103390948
gene id: 244447:LOC103390948
uniprot id: A0A3P8V6Q7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the P2X receptor family.
messages: Functional P2XRs are organized as homomeric and heteromeric trimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Receptor for ATP that acts as a ligand-gated ion channel.

244447:LOC103394691
gene id: 244447:LOC103394691
uniprot id: A0A3P8VRH3
names: Similarity
messages: Belongs to the TMEM106 family.

244447:nkx2-1
gene id: 244447:nkx2-1
uniprot id: A0A3P8V9J1
names: Subcellular Location Annotation
messages: Nucleus

244447:gins1
gene id: 244447:gins1
uniprot id: A0A3P8URD6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GINS1/PSF1 family.
messages: Chromosome
messages: Component of the GINS complex.
messages: Nucleus
messages: Required for correct functioning of the GINS complex, a complex that plays an essential role in the initiation of DNA replication, and progression of DNA replication forks. GINS complex seems to bind preferentially to single-stranded DNA.

244447:col4a6
gene id: 244447:col4a6
uniprot id: A0A3P8UFE6
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a 'chicken-wire' meshwork together with laminins, proteoglycans and entactin/nidogen.
messages: basement membrane

244447:acp1
gene id: 244447:acp1
uniprot id: A0A3P8WZS2
uniprot id: A0A3P8X4Y9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts on tyrosine phosphorylated proteins, low-MW aryl phosphates and natural and synthetic acyl phosphates.
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.
messages: Cytoplasm

244447:LOC103397778
gene id: 244447:LOC103397778
uniprot id: A0A3P8WVS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
messages: Cleavage furrow
messages: Midbody
messages: cilium membrane
messages: spindle

244447:rabggtb
gene id: 244447:rabggtb
uniprot id: A0A3P8X5K6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the protein prenyltransferase subunit beta family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the transfer of a geranylgeranyl moiety from geranylgeranyl diphosphate to both cysteines of proteins with the C-terminal sequence -XXCC, -XCXC and -CCXX.

244447:tm9sf1
gene id: 244447:tm9sf1
uniprot id: A0A3P8VL32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family.
messages: Membrane

244447:fgf2
gene id: 244447:fgf2
uniprot id: A0A3P8UYQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heparin-binding growth factors family.
messages: Nucleus
messages: Secreted

244447:LOC103379012
gene id: 244447:LOC103379012
uniprot id: A0A3P8VD18
names: Similarity
messages: Belongs to the lipin family.

244447:nck2
gene id: 244447:nck2
uniprot id: A0A3P8UWK3
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Endoplasmic reticulum

244447:LOC103389357
gene id: 244447:LOC103389357
uniprot id: A0A3P8UJ43
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the shroom family.
messages: cytoskeleton

244447:LOC103376777
gene id: 244447:LOC103376777
uniprot id: A0A3P8V132
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

244447:LOC103386813
gene id: 244447:LOC103386813
uniprot id: A0A3P8WYG4
names: Similarity
messages: Belongs to the MS4A family.

244447:psmg2
gene id: 244447:psmg2
uniprot id: A0A3P8W8A5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PSMG2 family.
messages: Chaperone protein which promotes assembly of the 20S proteasome as part of a heterodimer with PSMG1.
messages: Forms a heterodimer with PSMG1.

244447:LOC103385566
gene id: 244447:LOC103385566
uniprot id: A0A3P8WW13
names: Similarity
messages: Belongs to the serpin family.

244447:nt5dc2
gene id: 244447:nt5dc2
uniprot id: A0A3P8WUF9
names: Similarity
messages: Belongs to the 5'(3')-deoxyribonucleotidase family.

244447:LOC103391156
gene id: 244447:LOC103391156
uniprot id: A0A3P8W5E3
uniprot id: A0A3P8W5F3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type-B carboxylesterase/lipase family.
messages: Cell membrane
messages: Membrane

244447:tubgcp6
gene id: 244447:tubgcp6
uniprot id: A0A3P8VM94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TUBGCP family.
messages: centrosome

244447:LOC103382832
gene id: 244447:LOC103382832
uniprot id: A0A3P8VM85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

244447:LOC103378534
gene id: 244447:LOC103378534
uniprot id: A0A3P8UM78
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Interacts with ARRB1.
messages: Membrane

244447:LOC103385535
gene id: 244447:LOC103385535
uniprot id: A0A3P8X3H1
names: Function
names: Similarity
messages: Belongs to the vestigial family.
messages: May act as a specific coactivator for the mammalian TEFs.

244447:dhcr7
gene id: 244447:dhcr7
uniprot id: A0A3P8UE45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERG4/ERG24 family.
messages: Membrane

244447:LOC103395365
gene id: 244447:LOC103395365
uniprot id: A0A3P8WFB1
names: Subcellular Location Annotation
messages: Membrane

244447:calcb
gene id: 244447:calcb
uniprot id: A0A3P8UEK0
uniprot id: A0A3P8ULX8
names: Function
names: Similarity
messages: Belongs to the calcitonin family.
messages: Causes a rapid but short-lived drop in the level of calcium and phosphate in blood by promoting the incorporation of those ions in the bones.

244447:LOC103390320
gene id: 244447:LOC103390320
uniprot id: A0A3P8WX20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
messages: Nucleus

244447:pola2
gene id: 244447:pola2
uniprot id: A0A3P8V2I6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis.
messages: Belongs to the DNA polymerase alpha subunit B family.
messages: Nucleus

244447:cdk19
gene id: 244447:cdk19
uniprot id: A0A3P8WGK1
names: Similarity
messages: Belongs to the protein kinase superfamily.

244447:LOC103381038
gene id: 244447:LOC103381038
uniprot id: A0A3P8UN35
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel CLIC family.
messages: Cytoplasm
messages: Members of this family may change from a globular, soluble state to a state where the N-terminal domain is inserted into the membrane and functions as chloride channel. A conformation change of the N-terminal domain is thought to expose hydrophobic surfaces that trigger membrane insertion.
messages: Membrane

244447:narf
gene id: 244447:narf
uniprot id: A0A3P8UAX6
names: Similarity
messages: Belongs to the NARF family.

244447:LOC103393497
gene id: 244447:LOC103393497
uniprot id: A0A3P8WC25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

244447:LOC103388386
gene id: 244447:LOC103388386
uniprot id: A0A3P8V477
names: Similarity
messages: Belongs to the stathmin family.

244447:LOC103397733
gene id: 244447:LOC103397733
uniprot id: A0A3P8X164
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AB hydrolase superfamily. Lipase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

244447:LOC103382037
gene id: 244447:LOC103382037
uniprot id: A0A3P8WVL3
names: Function
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

244447:LOC103379428
gene id: 244447:LOC103379428
uniprot id: A0A3P8VYG9
names: Similarity
messages: Belongs to the FAM214 family.

244447:slc25a43
gene id: 244447:slc25a43
uniprot id: A0A3P8UYS3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

244447:atp5mg
gene id: 244447:atp5mg
uniprot id: A0A3P8VU20
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase g subunit family.
messages: Membrane
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. Minor subunit located with subunit a in the membrane.
messages: Mitochondrial membrane ATP synthase (F1F0 ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F1 - containing the extramembraneous catalytic core, and F0 - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F1 is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F0 domain. Minor subunit located with subunit a in the membrane.
messages: Mitochondrion

244447:LOC103398030
gene id: 244447:LOC103398030
uniprot id: A0A3P8VT12
names: Function
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
messages: Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues within the same substrate, with a preference for phosphotyrosine as a substrate (By similarity). Involved in the modulation of AMPK and MAPK1/2 signaling pathways.
messages: Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate.

244447:LOC103392034
gene id: 244447:LOC103392034
uniprot id: A0A3P8VR32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAPP small subunits family. Sedlin subfamily.
messages: perinuclear region

244447:LOC103380358
gene id: 244447:LOC103380358
uniprot id: A0A3P8VCQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAPRE family.
messages: cytoskeleton

244447:top2a
gene id: 244447:top2a
uniprot id: A0A3P8VXA4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type II topoisomerase family.
messages: Homodimer.
messages: Key decatenating enzyme that alters DNA topology by binding to two double-stranded DNA molecules, generating a double-stranded break in one of the strands, passing the intact strand through the broken strand, and religating the broken strand.
messages: nucleolus
messages: nucleoplasm

244447:parvb
gene id: 244447:parvb
uniprot id: A0A3P8VKZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the parvin family.
messages: cytoskeleton

244447:LOC103379993
gene id: 244447:LOC103379993
uniprot id: A0A3P8UR27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

244447:serp1
gene id: 244447:serp1
uniprot id: A0A3P8V907
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RAMP4 family.
messages: Endoplasmic reticulum membrane
messages: May interact with target proteins during translocation into the lumen of the endoplasmic reticulum. May protect unfolded target proteins against degradation and facilitate correct glycosylation.
messages: Membrane

244447:LOC103380180
gene id: 244447:LOC103380180
uniprot id: A0A3P8V643
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the round spermatid basic protein 1 family.
messages: Nucleus

244447:c4h19orf54
gene id: 244447:c4h19orf54
uniprot id: A0A3P8WP15
names: Similarity
messages: Belongs to the UPF0692 family.

244447:LOC103381193
gene id: 244447:LOC103381193
uniprot id: B2ZRV0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR3 subfamily.
messages: Nucleus

244447:LOC103379800
gene id: 244447:LOC103379800
uniprot id: A0A3P8UFG4
names: Similarity
messages: Belongs to the ATP:guanido phosphotransferase family.

244447:LOC103387638
gene id: 244447:LOC103387638
uniprot id: A0A3P8WGM4
uniprot id: A0A3P8WGN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SH3PXD2 family.
messages: Cytoplasm
messages: podosome

244447:LOC103379744
gene id: 244447:LOC103379744
uniprot id: A0A3P8UF44
names: Similarity
messages: Belongs to the aldo/keto reductase family.

244447:ap3d1
gene id: 244447:ap3d1
uniprot id: A0A3P8X2G1
names: Similarity
messages: Belongs to the adaptor complexes large subunit family.

244447:c1d
gene id: 244447:c1d
uniprot id: A0A3P8UC68
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the C1D family.
messages: Cytoplasm
messages: Monomer and homodimer.
messages: Nucleus
messages: Plays a role in the recruitment of the exosome to pre-rRNA to mediate the 3'-5' end processing of the 5.8S rRNA.
messages: nucleolus

244447:prkcz
gene id: 244447:prkcz
uniprot id: A0A3P8US94
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.

244447:clptm1l
gene id: 244447:clptm1l
uniprot id: A0A3P8VYV3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CLPTM1 family.
messages: Membrane

244447:fam219b
gene id: 244447:fam219b
uniprot id: A0A3P8VPF3
names: Similarity
messages: Belongs to the FAM219 family.

244447:qprt
gene id: 244447:qprt
uniprot id: A0A3P8WE46
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NadC/ModD family.
messages: Hexamer formed by 3 homodimers.
messages: Involved in the catabolism of quinolinic acid (QA).

244447:vcl
gene id: 244447:vcl
uniprot id: A0A3P8VIZ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Actin filament (F-actin)-binding protein involved in cell-matrix adhesion and cell-cell adhesion. Regulates cell-surface E-cadherin expression and potentiates mechanosensing by the E-cadherin complex. May also play important roles in cell morphology and locomotion.
messages: Belongs to the vinculin/alpha-catenin family.
messages: Cell membrane
messages: Membrane
messages: adherens junction

244447:LOC103397561
gene id: 244447:LOC103397561
uniprot id: A0A3P8WHF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTF2H2 family.
messages: Nucleus

244447:LOC103397976
gene id: 244447:LOC103397976
uniprot id: A0A3P8VMJ9
names: Subcellular Location Annotation
messages: Secreted

244447:rdh13
gene id: 244447:rdh13
uniprot id: A0A3P8VT02
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

244447:pkp1
gene id: 244447:pkp1
uniprot id: A0A3P8UK87
names: Similarity
messages: Belongs to the beta-catenin family.

244447:LOC103395528
gene id: 244447:LOC103395528
uniprot id: A0A3P8WW66
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: May be involved in podosome and invadosome formation.
messages: invadopodium
messages: podosome

244447:zdhhc18
gene id: 244447:zdhhc18
uniprot id: A0A3P8V558
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

244447:LOC103392014
gene id: 244447:LOC103392014
uniprot id: A0A3P8VP93
names: Subcellular Location Annotation
messages: Membrane

244447:ino80c
gene id: 244447:ino80c
uniprot id: A0A3P8VG48
names: Subcellular Location Annotation
messages: Nucleus

244447:LOC103381533
gene id: 244447:LOC103381533
uniprot id: A0A3P8VK40
uniprot id: A0A3P8VQJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PP2C family.
messages: Membrane
messages: cytosol

244447:ntmt1
gene id: 244447:ntmt1
uniprot id: A0A3P8WN37
names: Similarity
messages: Belongs to the methyltransferase superfamily. NTM1 family.

244447:dusp27
gene id: 244447:dusp27
uniprot id: A0A3P8VE83
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.

244447:slc25a48
gene id: 244447:slc25a48
uniprot id: A0A3P8VXV4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

244447:LOC103388882
gene id: 244447:LOC103388882
uniprot id: A0A3P8W2I9
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

244447:eri1
gene id: 244447:eri1
uniprot id: A0A3P8V160
names: Subcellular Location Annotation
messages: Cytoplasm

244447:flt3
gene id: 244447:flt3
uniprot id: A0A3P8WGA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
messages: Cell membrane
messages: Membrane

244447:LOC103397660
gene id: 244447:LOC103397660
uniprot id: A0A3P8WKB3
names: Similarity
messages: Belongs to the vasopressin/oxytocin family.

244447:med19
gene id: 244447:med19
uniprot id: A0A3P8VFX7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 19 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

244447:LOC103396120
gene id: 244447:LOC103396120
uniprot id: A0A3P8UAT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paired homeobox family. Bicoid subfamily.
messages: Nucleus

244447:ddx49
gene id: 244447:ddx49
uniprot id: A0A3P8WEZ1
names: Similarity
messages: Belongs to the DEAD box helicase family.

244447:me1
gene id: 244447:me1
uniprot id: A0A3P8VH14
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

244447:LOC103386467
gene id: 244447:LOC103386467
uniprot id: A0A3P8W201
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylin family.
messages: Secreted

244447:LOC103377882
gene id: 244447:LOC103377882
uniprot id: A0A3P8V3Q8
names: Subcellular Location Annotation
messages: Nucleus

244447:LOC103390531
gene id: 244447:LOC103390531
uniprot id: A0A3P8V8L1
names: Similarity
messages: Belongs to the DEAD box helicase family. DEAH subfamily. DDX15/PRP43 sub-subfamily.

244447:LOC103392083
gene id: 244447:LOC103392083
uniprot id: A0A3P8VVI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type-B carboxylesterase/lipase family.
messages: Cell membrane
messages: Membrane

244447:LOC103390441
gene id: 244447:LOC103390441
uniprot id: A0A3P8UP98
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

244447:actr6
gene id: 244447:actr6
uniprot id: A0A3P8X6G7
names: Similarity
messages: Belongs to the actin family. ARP6 subfamily.

244447:wdr45
gene id: 244447:wdr45
uniprot id: A0A3P8UP70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat PROPPIN family.
messages: Preautophagosomal structure

244447:letmd1
gene id: 244447:letmd1
uniprot id: A0A3P8X5U3
names: Subcellular Location Annotation
messages: Membrane

244447:chmp1b
gene id: 244447:chmp1b
uniprot id: A0A3P8WYZ3
names: Similarity
messages: Belongs to the SNF7 family.

244447:epc1
gene id: 244447:epc1
uniprot id: A0A3P8UER4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enhancer of polycomb family.
messages: Nucleus

244447:cacng3
gene id: 244447:cacng3
uniprot id: A0A3P8WV02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
messages: Membrane

244447:LOC103399871
gene id: 244447:LOC103399871
uniprot id: A0A3P8UMQ0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: Nucleus
messages: Perikaryon
messages: dendrite

244447:LOC103397970
gene id: 244447:LOC103397970
uniprot id: A0A3P8VDK4
uniprot id: A0A3P8VLW4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. NR1/GRIN1 subfamily.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

244447:LOC103388697
gene id: 244447:LOC103388697
uniprot id: A0A3P8VR73
names: Similarity
messages: Belongs to the peptidase C1 family.

244447:LOC103381011
gene id: 244447:LOC103381011
uniprot id: A0A3P8UQX6
names: Subcellular Location Annotation
messages: Membrane

244447:cacng7
gene id: 244447:cacng7
uniprot id: A0A3P8WRK2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Shows specificity only for GRIA1 and GRIA2.

244447:cd44
gene id: 244447:cd44
uniprot id: A0A3P8W4B5
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: microvillus

244447:leprotl1
gene id: 244447:leprotl1
uniprot id: A0A3P8UY04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OB-RGRP/VPS55 family.
messages: Membrane

244447:atp1b4
gene id: 244447:atp1b4
uniprot id: A0A3P8USG4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the X(+)/potassium ATPases subunit beta family.
messages: Membrane
messages: This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane.

244447:LOC103377102
gene id: 244447:LOC103377102
uniprot id: A0A3P8W388
uniprot id: A0A3P8W5N9
uniprot id: A0A3P8W5R5
uniprot id: A0A3P8W8N9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC12A transporter family.
messages: Membrane

244447:hectd1
gene id: 244447:hectd1
uniprot id: A0A3P8VRV9
names: Function
names: Similarity
messages: Belongs to the UPL family. K-HECT subfamily.
messages: E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.

244447:LOC103389980
gene id: 244447:LOC103389980
uniprot id: A0A3P8W1C1
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

244447:itgav
gene id: 244447:itgav
uniprot id: A0A3P8WC92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

244447:zc3hc1
gene id: 244447:zc3hc1
uniprot id: A0A3P8VMG3
names: Subcellular Location Annotation
messages: Nucleus

244447:LOC103377397
gene id: 244447:LOC103377397
uniprot id: A0A3P8WVX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CYRI family.
messages: Membrane

244447:LOC103381399
gene id: 244447:LOC103381399
uniprot id: A0A3P8V8U0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tdpoz family.
messages: Nucleus speckle

244447:LOC103385167
gene id: 244447:LOC103385167
uniprot id: A0A3P8VF31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.
messages: Nucleus

244447:barhl2
gene id: 244447:barhl2
uniprot id: A0A3P8VFG1
names: Subcellular Location Annotation
messages: Nucleus

244447:vta1
gene id: 244447:vta1
uniprot id: A0A3P8V7T1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VTA1 family.
messages: Cytoplasm
messages: Endosome membrane
messages: Membrane

244447:trpv1
gene id: 244447:trpv1
uniprot id: A0A3P8WEW0
names: Subcellular Location Annotation
messages: Membrane

244447:sarm1
gene id: 244447:sarm1
uniprot id: A0A3P8V9X0
names: Similarity
messages: Belongs to the SARM1 family.

244447:pde3b
gene id: 244447:pde3b
uniprot id: A0A3P8VKD5
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

244447:LOC103395715
gene id: 244447:LOC103395715
uniprot id: A0A3P8VHW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

244447:degs2
gene id: 244447:degs2
uniprot id: A0A3P8UJ54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acid desaturase type 1 family. DEGS subfamily.
messages: Endoplasmic reticulum membrane
messages: Membrane

244447:cfdp1
gene id: 244447:cfdp1
uniprot id: A0A3P8UP14
names: Function
names: Subcellular Location Annotation
messages: May play a role during embryogenesis.
messages: kinetochore

244447:LOC103397654
gene id: 244447:LOC103397654
uniprot id: A0A3P8WTX7
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

244447:phf2
gene id: 244447:phf2
uniprot id: A0A3P8W2Z9
names: Similarity
messages: Belongs to the JHDM1 histone demethylase family. JHDM1D subfamily.

244447:gale
gene id: 244447:gale
uniprot id: A0A3P8UID5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Catalyzes two distinct but analogous reactions: the reversible epimerization of UDP-glucose to UDP-galactose and the reversible epimerization of UDP-N-acetylglucosamine to UDP-N-acetylgalactosamine. The reaction with UDP-Gal plays a critical role in the Leloir pathway of galactose catabolism in which galactose is converted to the glycolytic intermediate glucose 6-phosphate. It contributes to the catabolism of dietary galactose and enables the endogenous biosynthesis of both UDP-Gal and UDP-GalNAc when exogenous sources are limited. Both UDP-sugar interconversions are important in the synthesis of glycoproteins and glycolipids.
messages: Homodimer.

244447:LOC103382638
gene id: 244447:LOC103382638
uniprot id: A0A3P8V8Y0
names: Similarity
messages: Belongs to the DSH family.

244447:LOC103381917
gene id: 244447:LOC103381917
uniprot id: A0A3P8WHH9
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

244447:pacs1
gene id: 244447:pacs1
uniprot id: A0A3P8UJ81
names: Similarity
messages: Belongs to the PACS family.

244447:gcg
gene id: 244447:gcg
uniprot id: A0A3P8VSU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glucagon family.
messages: Secreted

244447:ncoa2
gene id: 244447:ncoa2
uniprot id: A0A3P8W6R5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SRC/p160 nuclear receptor coactivator family.
messages: Nucleus

244447:LOC103395690
gene id: 244447:LOC103395690
uniprot id: A0A3P8VCV4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

244447:LOC103379807
gene id: 244447:LOC103379807
uniprot id: A0A3P8ULT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SAM50/omp85 family.
messages: Mitochondrion outer membrane

244447:wnt4
gene id: 244447:wnt4
uniprot id: A0A0A0QF77
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

244447:yipf4
gene id: 244447:yipf4
uniprot id: A0A3P8WGV0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YIP1 family.
messages: Membrane

244447:LOC103387194
gene id: 244447:LOC103387194
uniprot id: A0A3P8V0I6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

244447:ppm1e
gene id: 244447:ppm1e
uniprot id: A0A3P8WWF0
names: Similarity
messages: Belongs to the PP2C family.

244447:ppt1
gene id: 244447:ppt1
uniprot id: A0A3P8VM80
names: Similarity
messages: Belongs to the palmitoyl-protein thioesterase family.

244447:ykt6
gene id: 244447:ykt6
uniprot id: A0A3P8X2K5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Cytoplasmic vesicle membrane
messages: Golgi apparatus membrane
messages: Membrane
messages: Vesicular soluble NSF attachment protein receptor (v-SNARE) mediating vesicle docking and fusion to a specific acceptor cellular compartment. Functions in endoplasmic reticulum to Golgi transport; as part of a SNARE complex composed of GOSR1, GOSR2 and STX5. Functions in early/recycling endosome to TGN transport; as part of a SNARE complex composed of BET1L, GOSR1 and STX5. Has a S-palmitoyl transferase activity.

244447:cdpf1
gene id: 244447:cdpf1
uniprot id: A0A3P8VXI9
names: Similarity
messages: Belongs to the CDPF1 family.

244447:c17h16orf72
gene id: 244447:c17h16orf72
uniprot id: A0A3P8WNS5
names: Similarity
messages: Belongs to the TAPR1 family.

244447:hoga1
gene id: 244447:hoga1
uniprot id: A0A3P8WYH0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the final step in the metabolic pathway of hydroxyproline.
messages: Homotetramer.

244447:camk2b
gene id: 244447:camk2b
uniprot id: A0A3P8VDB3
uniprot id: A0A3P8VJ18
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily.

244447:LOC103399816
gene id: 244447:LOC103399816
uniprot id: A0A3P8ULS4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: cytosol

244447:gsc
gene id: 244447:gsc
uniprot id: A0A3P8WJG8
names: Subcellular Location Annotation
messages: Nucleus

244447:mag
gene id: 244447:mag
uniprot id: A0A3P8VYD3
uniprot id: A0A3P8W138
names: Subcellular Location Annotation
messages: Membrane

244447:nt5c3a
gene id: 244447:nt5c3a
uniprot id: A0A3P8VIW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrimidine 5'-nucleotidase family.
messages: Cytoplasm

244447:tmcc1
gene id: 244447:tmcc1
uniprot id: A0A3P8X697
names: Similarity
messages: Belongs to the TEX28 family.

244447:c1h20orf27
gene id: 244447:c1h20orf27
uniprot id: A0A3P8UZS4
names: Similarity
messages: Belongs to the UPF0687 family.

244447:LOC103390592
gene id: 244447:LOC103390592
uniprot id: A0A3P8USC4
uniprot id: A0A3P8UVH3
uniprot id: A0A3P8UX07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anion exchanger (TC 2.A.31) family.
messages: Membrane

244447:orc3
gene id: 244447:orc3
uniprot id: A0A3P8UKU7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ORC3 family.
messages: Component of ORC, a complex composed of at least 6 subunits: ORC1, ORC2, ORC3, ORC4, ORC5 and ORC6. ORC is regulated in a cell-cycle dependent manner. It is sequentially assembled at the exit from anaphase of mitosis and disassembled as cells enter S phase.
messages: Nucleus

244447:LOC103389857
gene id: 244447:LOC103389857
uniprot id: A0A3P8V4R1
names: Similarity
messages: Belongs to the methyltransferase superfamily.

244447:LOC103397055
gene id: 244447:LOC103397055
uniprot id: A0A3P8VXS8
names: Similarity
messages: Belongs to the PPP phosphatase family.

244447:LOC103393611
gene id: 244447:LOC103393611
uniprot id: A0A3P8W338
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

244447:LOC103393909
gene id: 244447:LOC103393909
uniprot id: A0A3P8VDC4
names: Function
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

244447:trmt61a
gene id: 244447:trmt61a
uniprot id: A0A3P8VZD5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM61 family.
messages: Catalytic subunit of tRNA (adenine-N(1)-)-methyltransferase, which catalyzes the formation of N(1)-methyladenine at position 58 (m1A58) in initiator methionyl-tRNA.
messages: Nucleus

244447:polr1b
gene id: 244447:polr1b
uniprot id: A0A3P8VLG8
names: Function
names: Similarity
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Second largest core component of RNA polymerase I which synthesizes ribosomal RNA precursors. Proposed to contribute to the polymerase catalytic activity and forms the polymerase active center together with the largest subunit. Pol I is composed of mobile elements and RPA2 is part of the core element with the central large cleft and probably a clamp element that moves to open and close the cleft.

244447:sema6a
gene id: 244447:sema6a
uniprot id: A0A3P8WW69
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

244447:foxi2
gene id: 244447:foxi2
uniprot id: A0A3P8VJW9
names: Subcellular Location Annotation
messages: Nucleus

244447:cnr1
gene id: 244447:cnr1
uniprot id: A0A3P8UZV1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: G-protein coupled receptor for cannabinoids. Mediates many cannabinoid-induced effects in the central nervous system (CNS), as well as in peripheral tissues. Signaling typically involves reduction in cyclic AMP.
messages: Membrane
messages: Mitochondrion outer membrane
messages: Presynapse
messages: Synapse
messages: axon

244447:eif4e2
gene id: 244447:eif4e2
uniprot id: A0A3P8W9R8
uniprot id: A0A3P8WF03
names: Similarity
messages: Belongs to the eukaryotic initiation factor 4E family.
messages: Belongs to the peptidase C2 family.

244447:zfp36l1
gene id: 244447:zfp36l1
uniprot id: A0A3P8VEU1
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Associates with the cytoplasmic CCR4-NOT deadenylase complex to trigger ARE-containing mRNA deadenylation and decay processes.
messages: Cytoplasm
messages: Nucleus
messages: Zinc-finger RNA-binding protein that destabilizes several cytoplasmic AU-rich element (ARE)-containing mRNA transcripts by promoting their poly(A) tail removal or deadenylation, and hence provide a mechanism for attenuating protein synthesis. Acts as a 3'-untranslated region (UTR) ARE mRNA-binding adapter protein to communicate signaling events to the mRNA decay machinery. Functions by recruiting the CCR4-NOT deadenylase complex and probably other components of the cytoplasmic RNA decay machinery to the bound ARE-containing mRNAs, and hence promotes ARE-mediated mRNA deadenylation and decay processes. Binds to 3'-UTR ARE of numerous mRNAs.

244447:LOC103389116
gene id: 244447:LOC103389116
uniprot id: A0A3P8WQ65
names: Similarity
messages: Belongs to the calycin superfamily. Lipocalin family.

244447:LOC103388544
gene id: 244447:LOC103388544
uniprot id: A0A3P8V2R3
names: Similarity
messages: Belongs to the stathmin family.

244447:LOC103386383
gene id: 244447:LOC103386383
uniprot id: A0A3P8VVR7
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

244447:mau2
gene id: 244447:mau2
uniprot id: A0A3P8V9H4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCC4/mau-2 family.
messages: nucleoplasm

244447:hmga1
gene id: 244447:hmga1
uniprot id: A0A3P8WKI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HMGA family.
messages: Nucleus

244447:ca8
gene id: 244447:ca8
uniprot id: A0A3P8WKC0
uniprot id: A0A3P8WN21
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.

244447:slc27a1
gene id: 244447:slc27a1
uniprot id: A0A3P8W0Q2
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

244447:ano6
gene id: 244447:ano6
uniprot id: A0A3P8VT22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anoctamin family.
messages: Membrane

244447:ppfia3
gene id: 244447:ppfia3
uniprot id: A0A3P8X0N2
names: Similarity
messages: Belongs to the liprin family. Liprin-alpha subfamily.

244447:plbd2
gene id: 244447:plbd2
uniprot id: A0A3P8WLB4
names: Function
names: Similarity
messages: Belongs to the phospholipase B-like family.
messages: Putative phospholipase.

244447:lin7a
gene id: 244447:lin7a
uniprot id: A0A3P8UWW4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lin-7 family.
messages: Cell junction
messages: Cell membrane
messages: Membrane
messages: Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells.

244447:idh3b
gene id: 244447:idh3b
uniprot id: A0A3P8WMW0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Heterooligomer of subunits alpha (IDH3A), beta (IDH3B), and gamma (IDH3G) in the apparent ratio of 2:1:1. The heterodimer containing one IDH3A and one IDH3B subunit and the heterodimer containing one IDH3A and one IDH3G subunit assemble into a heterotetramer (which contains two subunits of IDH3A, one of IDH3B and one of IDH3G) and further into the heterooctamer.
messages: Mitochondrion

244447:lin54
gene id: 244447:lin54
uniprot id: A0A3P8VPP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lin-54 family.
messages: Nucleus

244447:pde4c
gene id: 244447:pde4c
uniprot id: A0A3P8WEK4
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family. PDE4 subfamily.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

244447:LOC103384179
gene id: 244447:LOC103384179
uniprot id: A0A3P8WG38
names: Similarity
messages: Belongs to the aldo/keto reductase family.

244447:pithd1
gene id: 244447:pithd1
uniprot id: A0A3P8VDF8
names: Similarity
messages: Belongs to the PITHD1 family.

244447:LOC103388287
gene id: 244447:LOC103388287
uniprot id: A0A3P8UU88
names: Similarity
messages: Belongs to the CAS family.

244447:LOC103391244
gene id: 244447:LOC103391244
uniprot id: A0A3P8WAZ5
names: Subcellular Location Annotation
messages: Membrane

244447:LOC103395360
gene id: 244447:LOC103395360
uniprot id: A0A3P8WBZ1
names: Similarity
messages: Belongs to the peptidase C2 family.

244447:rad18
gene id: 244447:rad18
uniprot id: A0A3P8UPT1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RAD18 family.
messages: Nucleus

244447:LOC103386010
gene id: 244447:LOC103386010
uniprot id: A0A3P8V0G7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP-alpha family.
messages: Endoplasmic reticulum membrane
messages: Heterotetramer of TRAP-alpha, TRAP-beta, TRAP-delta and TRAP-gamma.
messages: Membrane
messages: Shows a remarkable charge distribution with the N-terminus being highly negatively charged, and the cytoplasmic C-terminus positively charged.
messages: TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins. May be involved in the recycling of the translocation apparatus after completion of the translocation process or may function as a membrane-bound chaperone facilitating folding of translocated proteins.

244447:ip6k1
gene id: 244447:ip6k1
uniprot id: A0A3P8WW36
names: Similarity
messages: Belongs to the inositol phosphokinase (IPK) family.

244447:LOC103380585
gene id: 244447:LOC103380585
uniprot id: A0A3P8WCE3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

244447:usp3
gene id: 244447:usp3
uniprot id: A0A3P8UML1
names: Similarity
messages: Belongs to the peptidase C19 family.

244447:gle1
gene id: 244447:gle1
uniprot id: A0A3P8W8D5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GLE1 family.
messages: Required for the export of mRNAs containing poly(A) tails from the nucleus into the cytoplasm. May be involved in the terminal step of the mRNA transport through the nuclear pore complex (NPC).
messages: nuclear pore complex

244447:rad17
gene id: 244447:rad17
uniprot id: A0A3P8VIK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the rad17/RAD24 family.
messages: Nucleus

244447:nrn1
gene id: 244447:nrn1
uniprot id: A0A3P8WP55
names: Similarity
messages: Belongs to the neuritin family.

244447:LOC103385953
gene id: 244447:LOC103385953
uniprot id: A0A3P8UXE0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Membrane

244447:LOC103387541
gene id: 244447:LOC103387541
uniprot id: A0A3P8VV77
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZIP transporter (TC 2.A.5) family.
messages: May act as a zinc-influx transporter.
messages: Membrane

244447:LOC103385401
gene id: 244447:LOC103385401
uniprot id: A0A3P8WXI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NKAIN family.
messages: Cell membrane
messages: Membrane

244447:LOC103386830
gene id: 244447:LOC103386830
uniprot id: A0A3P8WZ05
names: Similarity
messages: Belongs to the PP2C family.

244447:LOC103377952
gene id: 244447:LOC103377952
uniprot id: A0A3P8V4K5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pannexin family.
messages: Cell membrane
messages: Membrane
messages: Structural component of the gap junctions and the hemichannels.
messages: gap junction

244447:LOC103386987
gene id: 244447:LOC103386987
uniprot id: A0A3P8ULR9
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

244447:heg1
gene id: 244447:heg1
uniprot id: A0A3P8VZX4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

244447:dtd2
gene id: 244447:dtd2
uniprot id: A0A3P8W6T0
names: Similarity
messages: Belongs to the DTD family.

244447:LOC103388746
gene id: 244447:LOC103388746
uniprot id: A0A3P8UA59
names: Similarity
messages: Belongs to the CEP170 family.

244447:LOC103393291
gene id: 244447:LOC103393291
uniprot id: M4GXZ4
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

244447:psma1
gene id: 244447:psma1
uniprot id: A0A3P8ULZ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essential roles within the cell by associating with different regulatory particles. Associated with two 19S regulatory particles, forms the 26S proteasome and thus participates in the ATP-dependent degradation of ubiquitinated proteins. The 26S proteasome plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins that could impair cellular functions, and by removing proteins whose functions are no longer required. Associated with the PA200 or PA28, the 20S proteasome mediates ubiquitin-independent protein degradation. This type of proteolysis is required in several pathways including spermatogenesis (20S-PA200 complex) or generation of a subset of MHC class I-presented antigenic peptides (20S-PA28 complex).
messages: Cytoplasm
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.

244447:afg1l
gene id: 244447:afg1l
uniprot id: A0A3P8WRL1
names: Similarity
messages: Belongs to the AFG1 ATPase family.

244447:LOC103387200
gene id: 244447:LOC103387200
uniprot id: A0A3P8UYP1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sideroflexin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Mitochondrion membrane

244447:polr2d
gene id: 244447:polr2d
uniprot id: A0A3P8V660
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic RPB4 RNA polymerase subunit family.
messages: Nucleus

244447:LOC103382354
gene id: 244447:LOC103382354
uniprot id: A0A3P8UGA4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

244447:LOC103380937
gene id: 244447:LOC103380937
uniprot id: A0A3P8X4I1
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.

244447:coq2
gene id: 244447:coq2
uniprot id: A0A3P8WEG1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family.
messages: Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate.
messages: Mitochondrion inner membrane

244447:e2f2
gene id: 244447:e2f2
uniprot id: A0A3P8UQJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the E2F/DP family.
messages: Nucleus

244447:chst12
gene id: 244447:chst12
uniprot id: A0A3P8X4E5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 2 family.
messages: Golgi apparatus membrane
messages: Membrane

244447:LOC103397002
gene id: 244447:LOC103397002
uniprot id: A0A3P8VLK4
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

244447:sntg1
gene id: 244447:sntg1
uniprot id: A0A3P8VL46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the syntrophin family.
messages: cytoskeleton

244447:LOC103386082
gene id: 244447:LOC103386082
uniprot id: A0A3P8UXA4
names: Subcellular Location Annotation
messages: Cytoplasm

244447:LOC103384292
gene id: 244447:LOC103384292
uniprot id: A0A3P8WCP8
names: Similarity
messages: Belongs to the Rho GDI family.

244447:LOC103377546
gene id: 244447:LOC103377546
uniprot id: A0A3P8UJC8
names: Similarity
names: Subunit
messages: Belongs to the 14-3-3 family.
messages: Homodimer, and heterodimer with other family members.

244447:LOC103396604
gene id: 244447:LOC103396604
uniprot id: A0A3P8WZQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essential roles within the cell by associating with different regulatory particles. Associated with two 19S regulatory particles, forms the 26S proteasome and thus participates in the ATP-dependent degradation of ubiquitinated proteins. The 26S proteasome plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins that could impair cellular functions, and by removing proteins whose functions are no longer required. Associated with the PA200 or PA28, the 20S proteasome mediates ubiquitin-independent protein degradation. This type of proteolysis is required in several pathways including spermatogenesis (20S-PA200 complex) or generation of a subset of MHC class I-presented antigenic peptides (20S-PA28 complex). Within the 20S core complex, PSMB5 displays a chymotrypsin-like activity.
messages: Component of the proteasome complex.
messages: Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
messages: Cytoplasm
messages: Nucleus
messages: The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. This subunit is involved in antigen processing to generate class I binding peptides.

244447:clrn1
gene id: 244447:clrn1
uniprot id: A0A3P8VBF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the clarin family.
messages: Membrane

244447:e2f1
gene id: 244447:e2f1
uniprot id: A0A3P8UYY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the E2F/DP family.
messages: Nucleus

244447:LOC103389907
gene id: 244447:LOC103389907
uniprot id: A0A3P8VWC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MOZART2 family.
messages: centrosome
messages: spindle

244447:LOC103385743
gene id: 244447:LOC103385743
uniprot id: A0A3P8UK12
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the caveolin family.
messages: Cell membrane
messages: Golgi apparatus membrane
messages: May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity.
messages: Membrane
messages: caveola

244447:psmb3
gene id: 244447:psmb3
uniprot id: A0A3P8WJ28
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome complex.
messages: Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
messages: Cytoplasm
messages: Nucleus

244447:LOC103390057
gene id: 244447:LOC103390057
uniprot id: A0A3P8WD27
names: Domain
names: Function
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
messages: Converts 1-acyl-sn-glycerol-3-phosphate (lysophosphatidic acid or LPA) into 1,2-diacyl-sn-glycerol-3-phosphate (phosphatidic acid or PA) by incorporating an acyl moiety at the sn-2 position of the glycerol backbone.
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

244447:tnmd
gene id: 244447:tnmd
uniprot id: A0A3P8UPU2
names: Similarity
messages: Belongs to the chondromodulin-1 family.

244447:LOC103394580
gene id: 244447:LOC103394580
uniprot id: A0A3P8WGJ0
names: Similarity
messages: Belongs to the TCF/LEF family.

244447:cfi
gene id: 244447:cfi
uniprot id: A0A0H4CX09
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular space

244447:LOC103395957
gene id: 244447:LOC103395957
uniprot id: A0A3P8W7S8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the potassium channel HCN family.
messages: Cell membrane
messages: Membrane

244447:sorcs2
gene id: 244447:sorcs2
uniprot id: A0A3P8WWB0
names: Similarity
messages: Belongs to the VPS10-related sortilin family. SORCS subfamily.

244447:tram2
gene id: 244447:tram2
uniprot id: A0A3P8UEZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAM family.
messages: Membrane

244447:prkce
gene id: 244447:prkce
uniprot id: A0A3P8VHL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
messages: Cytoplasm

244447:LOC103376847
gene id: 244447:LOC103376847
uniprot id: A0A3P8VKF2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.

244447:dimt1
gene id: 244447:dimt1
uniprot id: A0A3P8WH24
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.

244447:gab3
gene id: 244447:gab3
uniprot id: A0A3P8W1P7
names: Similarity
messages: Belongs to the GAB family.

244447:orc4
gene id: 244447:orc4
uniprot id: A0A3P8V869
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ORC4 family.
messages: Component of the origin recognition complex (ORC) that binds origins of replication.
messages: Nucleus

244447:LOC103389902
gene id: 244447:LOC103389902
uniprot id: A0A3P8VTR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HMG-CoA reductase family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Peroxisome membrane

244447:KEH01 p11
gene id: 244447:KEH01_p11
uniprot id: C1K5A8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
messages: Membrane
messages: Mitochondrion inner membrane

244447:LOC103384885
gene id: 244447:LOC103384885
uniprot id: A0A3P8UVS7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

244447:LOC103386156
gene id: 244447:LOC103386156
uniprot id: A0A3P8V7Y1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

244447:shoc2
gene id: 244447:shoc2
uniprot id: A0A3P8VUU4
names: Function
names: Similarity
messages: Belongs to the SHOC2 family.
messages: Regulatory subunit of protein phosphatase 1 (PP1c) that acts as a M-Ras/MRAS effector and participates in MAPK pathway activation. Upon M-Ras/MRAS activation, targets PP1c to specifically dephosphorylate the 'Ser-259' inhibitory site of RAF1 kinase and stimulate RAF1 activity at specialized signaling complexes.

244447:epo
gene id: 244447:epo
uniprot id: A0A3P8W212
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPO/TPO family.
messages: Erythropoietin is the principal hormone involved in the regulation of erythrocyte differentiation and the maintenance of a physiological level of circulating erythrocyte mass.
messages: Secreted

244447:bcdin3d
gene id: 244447:bcdin3d
uniprot id: A0A3P8WWD5
names: Similarity
messages: Belongs to the methyltransferase superfamily.

244447:LOC103392115
gene id: 244447:LOC103392115
uniprot id: A0A3P8VUB4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family. Alpha-type (group II) subfamily.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

244447:echs1
gene id: 244447:echs1
uniprot id: A0A3P8V9I0
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

244447:diaph3
gene id: 244447:diaph3
uniprot id: A0A3P8UL53
names: Similarity
messages: Belongs to the formin homology family. Diaphanous subfamily.

244447:gtpbp1
gene id: 244447:gtpbp1
uniprot id: A0A3P8VYP8
uniprot id: A0A3P8W1B6
names: Function
messages: Promotes degradation of target mRNA species. Plays a role in the regulation of circadian mRNA stability. Binds GTP and has GTPase activity.

244447:LOC103397626
gene id: 244447:LOC103397626
uniprot id: A0A3P8WWY1
names: Subcellular Location Annotation
messages: Nucleus

244447:LOC103384942
gene id: 244447:LOC103384942
uniprot id: A0A3P8V4V8
names: Subcellular Location Annotation
messages: extracellular space

244447:LOC103396908
gene id: 244447:LOC103396908
uniprot id: A0A3P8VHI6
names: Subcellular Location Annotation
names: Subunit
messages: May interact with TSPO.
messages: Mitochondrion

244447:ndufs8
gene id: 244447:ndufs8
uniprot id: A0A3P8WAD4
names: Similarity
messages: Belongs to the complex I 23 kDa subunit family.

244447:LOC103379236
gene id: 244447:LOC103379236
uniprot id: A0A3P8VG71
names: Function
names: Similarity
messages: Belongs to the glyoxalase I family.
messages: Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione.

244447:usb1
gene id: 244447:usb1
uniprot id: A0A3P8WAX5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 2H phosphoesterase superfamily. USB1 family.
messages: Nucleus
messages: Phosphodiesterase responsible for the U6 snRNA 3' end processing. Acts as an exoribonuclease (RNase) responsible for trimming the poly(U) tract of the last nucleotides in the pre-U6 snRNA molecule, leading to the formation of mature U6 snRNA.

244447:LOC103394016
gene id: 244447:LOC103394016
uniprot id: A0A3P8VVE5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTR/RAG GTP-binding protein family.
messages: Cytoplasm
messages: Guanine nucleotide-binding protein that plays a crucial role in the cellular response to amino acid availability through regulation of the mTORC1 signaling cascade.
messages: Lysosome

244447:LOC103383373
gene id: 244447:LOC103383373
uniprot id: A0A3P8ULI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tom20 family.
messages: Membrane
messages: Mitochondrion outer membrane

244447:parg
gene id: 244447:parg
uniprot id: A0A3P8UY35
names: Similarity
messages: Belongs to the poly(ADP-ribose) glycohydrolase family.

244447:cep57l1
gene id: 244447:cep57l1
uniprot id: A0A3P8WLR0
names: Similarity
messages: Belongs to the translokin family.

244447:LOC103392311
gene id: 244447:LOC103392311
uniprot id: A0A3P8W5G9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

244447:ezh2
gene id: 244447:ezh2
uniprot id: A0A3P8WEX7
names: Subcellular Location Annotation
messages: Nucleus

244447:slc35f1
gene id: 244447:slc35f1
uniprot id: A0A3P8WDW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC35F solute transporter family.
messages: Membrane

244447:LOC103377935
gene id: 244447:LOC103377935
uniprot id: A0A3P8V7P2
names: Similarity
messages: Belongs to the cullin family.

244447:LOC103385311
gene id: 244447:LOC103385311
uniprot id: A0A3P8WN55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

244447:acvr1b
gene id: 244447:acvr1b
uniprot id: A0A3P8VEW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Membrane

244447:LOC103383745
gene id: 244447:LOC103383745
uniprot id: A0A3P8V942
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tyrosinase family.
messages: Melanosome membrane

244447:LOC103385803
gene id: 244447:LOC103385803
uniprot id: A0A3P8UQS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF2/RAD54 helicase family.
messages: Nucleus

244447:LOC103377439
gene id: 244447:LOC103377439
uniprot id: A0A3P8UI92
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane
messages: Membrane

244447:dopey1
gene id: 244447:dopey1
uniprot id: A0A3P8VHG2
uniprot id: A0A3P8VHI4
names: Similarity
messages: Belongs to the dopey family.

244447:cp
gene id: 244447:cp
uniprot id: A0A3P8WS05
uniprot id: A0A3P8WU19
names: Similarity
messages: Belongs to the multicopper oxidase family.

244447:LOC103390154
gene id: 244447:LOC103390154
uniprot id: A0A3P8WIX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GLI C2H2-type zinc-finger protein family.
messages: Nucleus

244447:LOC103379187
gene id: 244447:LOC103379187
uniprot id: A0A3P8UZ58
names: Similarity
messages: Belongs to the GADD45 family.

244447:asic4
gene id: 244447:asic4
uniprot id: A0A3P8WB00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family.
messages: Cell membrane
messages: Membrane

244447:steap3
gene id: 244447:steap3
uniprot id: A0A3P8VJE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STEAP family.
messages: Endosome membrane
messages: Membrane

244447:LOC103393687
gene id: 244447:LOC103393687
uniprot id: A0A3P8WD03
names: Similarity
messages: Belongs to the folate receptor family.

244447:LOC103382295
gene id: 244447:LOC103382295
uniprot id: A0A3P8UMT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

244447:gpc6
gene id: 244447:gpc6
uniprot id: A0A3P8VPH9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glypican family.
messages: Cell membrane
messages: Cell surface proteoglycan that bears heparan sulfate.

244447:LOC103396071
gene id: 244447:LOC103396071
uniprot id: A0A3P8WNU8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

244447:cab39l
gene id: 244447:cab39l
uniprot id: A0A3P8USA5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mo25 family.
messages: Component of a complex that binds and activates STK11/LKB1. In the complex, required to stabilize the interaction between CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta) and STK11/LKB1.
messages: Component of a trimeric complex composed of STK11/LKB1, STRAD (STRADA or STRADB) and CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta): the complex tethers STK11/LKB1 in the cytoplasm and stimulates its catalytic activity.

244447:LOC103393221
gene id: 244447:LOC103393221
uniprot id: A0A3P8WPV7
names: Similarity
messages: Belongs to the yippee family.

244447:LOC103391243
gene id: 244447:LOC103391243
uniprot id: A0A3P8WHG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the N4BP3 family.
messages: Cytoplasmic vesicle
messages: Vesicle
messages: axon
messages: dendrite

244447:traf3
gene id: 244447:traf3
uniprot id: A0A3P8VWM0
uniprot id: A0A3P8W1W6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TNF receptor-associated factor family.
messages: Cytoplasm

244447:ost4
gene id: 244447:ost4
uniprot id: A0A3P8WQS1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OST4 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

244447:popdc2
gene id: 244447:popdc2
uniprot id: A0A3P8VJ43
names: Similarity
messages: Belongs to the popeye family.

244447:atp5s
gene id: 244447:atp5s
uniprot id: A0A3P8VCP5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP synthase subunit s family.
messages: Homotetramer. Associates with ATP synthase.
messages: Involved in regulation of mitochondrial membrane ATP synthase. Necessary for H(+) conduction of ATP synthase. Facilitates energy-driven catalysis of ATP synthesis by blocking a proton leak through an alternative proton exit pathway.
messages: Membrane
messages: Mitochondrion inner membrane

244447:mrpl40
gene id: 244447:mrpl40
uniprot id: A0A3P8WVN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL40 family.
messages: Mitochondrion

244447:LOC103381794
gene id: 244447:LOC103381794
uniprot id: A0A3P8W9J6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-alpha family. G(12) subfamily.
messages: Membrane

244447:LOC103389825
gene id: 244447:LOC103389825
uniprot id: A0A3P8VGM6
uniprot id: A0A3P8VPV1
names: Similarity
messages: Belongs to the centaurin gamma-like family.

244447:dsp
gene id: 244447:dsp
uniprot id: A0A3P8VNE9
names: Subcellular Location Annotation
messages: cytoskeleton

244447:oxr1
gene id: 244447:oxr1
uniprot id: A0A3P8VN99
names: Similarity
messages: Belongs to the OXR1 family.

244447:cln3
gene id: 244447:cln3
uniprot id: A0A3P8W4A6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the battenin family.
messages: Lysosome membrane
messages: Membrane

244447:mettl3
gene id: 244447:mettl3
uniprot id: A0A3P8UX03
names: Similarity
messages: Belongs to the MT-A70-like family.

244447:ppp2r5b
gene id: 244447:ppp2r5b
uniprot id: A0A3P8WI23
names: Similarity
messages: Belongs to the phosphatase 2A regulatory subunit B56 family.

244447:ak6
gene id: 244447:ak6
uniprot id: A0A3P8VIJ3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family. AK6 subfamily.
messages: Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. May have a role in nuclear energy homeostasis. Has also ATPase activity. May be involved in regulation of Cajal body (CB) formation.
messages: Cajal body
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer and homodimer. Interacts with COIL (via C-terminus).
messages: nucleoplasm

244447:cdo1
gene id: 244447:cdo1
uniprot id: A0A3P8WU69
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the cysteine dioxygenase family.
messages: Binds 1 Fe cation per subunit.
messages: Catalyzes the oxidation of cysteine to cysteine sulfinic acid with addition of molecular dioxygen.

244447:ptpra
gene id: 244447:ptpra
uniprot id: A0A3P8WT07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Receptor class 4 subfamily.
messages: Cell membrane
messages: Membrane

244447:LOC103391498
gene id: 244447:LOC103391498
uniprot id: A0A3P8WZT3
names: Similarity
messages: Belongs to the RRP1 family.

244447:hoxc4
gene id: 244447:hoxc4
uniprot id: A0A3P8V967
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

244447:LOC103395728
gene id: 244447:LOC103395728
uniprot id: A0A3P8WW52
names: Subcellular Location Annotation
messages: Membrane

244447:LOC103383696
gene id: 244447:LOC103383696
uniprot id: A0A3P8UV02
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CNTF family.
messages: CNTF is a survival factor for various neuronal cell types. Seems to prevent the degeneration of motor axons after axotomy.
messages: Cytoplasm

244447:polrmt
gene id: 244447:polrmt
uniprot id: A0A3P8UQS6
names: Function
names: Similarity
messages: Belongs to the phage and mitochondrial RNA polymerase family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.

244447:LOC103378773
gene id: 244447:LOC103378773
uniprot id: A0A3P8USX3
names: Similarity
messages: Belongs to the glycosyl hydrolase 23 family.

244447:pik3c3
gene id: 244447:pik3c3
uniprot id: A0A3P8UT11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.
messages: Midbody

244447:LOC103380108
gene id: 244447:LOC103380108
uniprot id: A0A3P8V7F6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELL/occludin family.
messages: Nucleus

244447:LOC103389985
gene id: 244447:LOC103389985
uniprot id: A0A3P8VWQ4
names: Similarity
messages: Belongs to the FBPase class 1 family.

244447:LOC103397653
gene id: 244447:LOC103397653
uniprot id: A0A3P8WL01
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Cell membrane
messages: Membrane
messages: Membrane raft
messages: caveola

244447:LOC103393183
gene id: 244447:LOC103393183
uniprot id: A0A3P8WIW2
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: The potassium channel is probably composed of a homo- or heterotetrameric complex of pore-forming alpha subunits that can associate with modulating beta subunits.

244447:polr2j
gene id: 244447:polr2j
uniprot id: A0A3P8WWC9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal Rpo11/eukaryotic RPB11/RPC19 RNA polymerase subunit family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB11 is part of the core element with the central large cleft.
messages: Nucleus

244447:LOC103393692
gene id: 244447:LOC103393692
uniprot id: A0A3P8WB61
names: Subcellular Location Annotation
messages: Nucleus

244447:kcnab2
gene id: 244447:kcnab2
uniprot id: A0A3P8X3T8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the shaker potassium channel beta subunit family.
messages: Cell membrane
messages: Cytoplasm
messages: Membrane

244447:LOC103381501
gene id: 244447:LOC103381501
uniprot id: A0A3P8VF74
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP dependent phosphorylation of adenosine and other related nucleoside analogs to monophosphate derivatives.
messages: Belongs to the carbohydrate kinase PfkB family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Monomer.
messages: Nucleus

244447:LOC103385198
gene id: 244447:LOC103385198
uniprot id: A0A3P8VK99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

244447:LOC103396191
gene id: 244447:LOC103396191
uniprot id: A0A3P8WPK2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complement C6/C7/C8/C9 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

244447:LOC103378706
gene id: 244447:LOC103378706
uniprot id: A0A3P8UP02
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein P1/P2 family.
messages: Heterodimer with RPLP1 at the lateral ribosomal stalk of the large ribosomal subunit.
messages: Plays an important role in the elongation step of protein synthesis.

244447:phkg2
gene id: 244447:phkg2
uniprot id: A0A3P8W430
names: Similarity
names: Subunit
messages: Belongs to the protein kinase superfamily.
messages: Hexadecamer of 4 heterotetramers, each composed of alpha, beta, gamma, and delta subunits. Alpha (PHKA1 or PHKA2) and beta (PHKB) are regulatory subunits, gamma (PHKG1 or PHKG2) is the catalytic subunit, and delta is calmodulin.

244447:LOC103392078
gene id: 244447:LOC103392078
uniprot id: A0A3P8VP68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Receptor class 8 subfamily.
messages: Membrane
messages: secretory vesicle membrane

244447:taf13
gene id: 244447:taf13
uniprot id: A0A3P8UMM2
names: Subcellular Location Annotation
messages: Nucleus

244447:rfc4
gene id: 244447:rfc4
uniprot id: A0A3P8UE23
names: Similarity
messages: Belongs to the activator 1 small subunits family.

244447:rpl14
gene id: 244447:rpl14
uniprot id: A0A3P8VTD9
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL14 family.

244447:lias
gene id: 244447:lias
uniprot id: A0A3P8UWB7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Mitochondrion

244447:aqp11
gene id: 244447:aqp11
uniprot id: A0A3P8V4G5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Aquaporins facilitate the transport of water and small neutral solutes across cell membranes.
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family. AQP11/AQP12 subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

244447:ctsd
gene id: 244447:ctsd
uniprot id: G9D325
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A1 family.
messages: Lysosome

244447:LOC103384022
gene id: 244447:LOC103384022
uniprot id: A0A3P8VV41
uniprot id: A0A3P8VV52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCDC85 family.
messages: adherens junction

244447:LOC103386512
gene id: 244447:LOC103386512
uniprot id: A0A3P8UFC2
names: Similarity
messages: Belongs to the galactose-3-O-sulfotransferase family.

244447:cpm
gene id: 244447:cpm
uniprot id: A0A3P8V0R8
names: Similarity
messages: Belongs to the peptidase M14 family.

244447:abhd3
gene id: 244447:abhd3
uniprot id: A0A3P8W2Z3
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 4 family.

244447:sec22a
gene id: 244447:sec22a
uniprot id: A0A3P8V2U4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Endoplasmic reticulum membrane
messages: May be involved in vesicle transport between the ER and the Golgi complex.
messages: Membrane

244447:LOC103399814
gene id: 244447:LOC103399814
uniprot id: A0A3P8UHR5
names: Function
messages: Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.

244447:unc93a
gene id: 244447:unc93a
uniprot id: A0A3P8UWS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the unc-93 family.
messages: Membrane

244447:hal
gene id: 244447:hal
uniprot id: A0A3P8W9L0
names: Similarity
messages: Belongs to the PAL/histidase family.

244447:arl2bp
gene id: 244447:arl2bp
uniprot id: A0A3P8X668
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ARL2BP family.
messages: Cytoplasm
messages: Mitochondrion intermembrane space
messages: Nucleus
messages: Plays a role as an effector of the ADP-ribosylation factor-like protein 2, ARL2.
messages: centrosome
messages: cilium basal body

244447:LOC103394470
gene id: 244447:LOC103394470
uniprot id: A0A3P8WNQ7
names: Caution
names: Similarity
messages: Belongs to the sclerostin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

244447:setd2
gene id: 244447:setd2
uniprot id: A0A3P8UXM4
names: Subcellular Location Annotation
messages: Nucleus

244447:ldlrad4
gene id: 244447:ldlrad4
uniprot id: A0A3P8W0N7
uniprot id: A0A3P8W3K0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMEPA1 family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

244447:mrpl52
gene id: 244447:mrpl52
uniprot id: A0A3P8UUA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL52 family.
messages: Mitochondrion

244447:acss3
gene id: 244447:acss3
uniprot id: A0A3P8V339
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

244447:LOC103380519
gene id: 244447:LOC103380519
uniprot id: A0A3P8W5Q3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonium transporter (TC 2.A.49) family. Rh subfamily.
messages: Cell membrane
messages: Functions as an ammonia transporter. May play a role in the elimination of ammonia in the gill.
messages: Membrane

244447:LOC103385370
gene id: 244447:LOC103385370
uniprot id: A0A3P8WXB5
names: Similarity
messages: Belongs to the nucleosome assembly protein (NAP) family.

244447:pc
gene id: 244447:pc
uniprot id: A0A3P8WU01
names: Function
messages: Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.

244447:LOC103377954
gene id: 244447:LOC103377954
uniprot id: A0A3P8VD39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

244447:LOC103393525
gene id: 244447:LOC103393525
uniprot id: A0A3P8W9B0
names: Subcellular Location Annotation
messages: Cytoplasm

244447:LOC103380957
gene id: 244447:LOC103380957
uniprot id: A0A3P8UJJ1
names: Function
names: Similarity
messages: Belongs to the E(R) family.
messages: May have a role in the cell cycle.

244447:LOC103383231
gene id: 244447:LOC103383231
uniprot id: A0A3P8X598
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Cell surface
messages: Endosome
messages: Membrane

244447:LOC103396359
gene id: 244447:LOC103396359
uniprot id: A0A3P8VZF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIP family.
messages: adherens junction
messages: centriolar satellite

244447:LOC103394950
gene id: 244447:LOC103394950
uniprot id: A0A3P8WMM3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the shroom family.
messages: cytoskeleton

244447:runx2
gene id: 244447:runx2
uniprot id: A0A3P8WKF3
names: Subcellular Location Annotation
messages: Nucleus

244447:emc8
gene id: 244447:emc8
uniprot id: A0A3P8WE66
names: Similarity
messages: Belongs to the EMC8/EMC9 family.

244447:s1pr1
gene id: 244447:s1pr1
uniprot id: A0A3P8UJ85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

244447:pttg1
gene id: 244447:pttg1
uniprot id: A0A3P8UL32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the securin family.
messages: Cytoplasm
messages: Nucleus

244447:snrpb
gene id: 244447:snrpb
uniprot id: A0A3P8X1Z5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP SmB/SmN family.
messages: Nucleus

244447:tmed9
gene id: 244447:tmed9
uniprot id: A0A3P8VZQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Endoplasmic reticulum membrane
messages: Membrane

244447:LOC103395785
gene id: 244447:LOC103395785
uniprot id: A0A3P8VKJ4
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.

244447:nfib
gene id: 244447:nfib
uniprot id: A0A3P8VHG1
uniprot id: A0A3P8VNA1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CTF/NF-I family.
messages: Binds DNA as a homodimer.
messages: Nucleus
messages: Recognizes and binds the palindromic sequence 5'-TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication.

244447:marveld2
gene id: 244447:marveld2
uniprot id: A0A3P8WE92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELL/occludin family.
messages: Cell membrane
messages: Membrane
messages: tight junction

244447:LOC103381617
gene id: 244447:LOC103381617
uniprot id: A0A3P8VK23
names: Subcellular Location Annotation
messages: Membrane

244447:LOC103396032
gene id: 244447:LOC103396032
uniprot id: A0A3P8WIE6
names: Similarity
messages: Belongs to the aldo/keto reductase family.

244447:LOC103390849
gene id: 244447:LOC103390849
uniprot id: A0A3P8V6L7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sestrin family.
messages: Cytoplasm

244447:LOC103376709
gene id: 244447:LOC103376709
uniprot id: A0A3P8UCM4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

244447:LOC103390585
gene id: 244447:LOC103390585
uniprot id: A0A3P8UMH1
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL42 family.

244447:cops6
gene id: 244447:cops6
uniprot id: A0A3P8URI6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M67A family. CSN6 subfamily.
messages: Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes.
messages: Cytoplasm
messages: Nucleus

244447:fam3a
gene id: 244447:fam3a
uniprot id: A0A3P8UFY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM3 family.
messages: Secreted

244447:LOC103380539
gene id: 244447:LOC103380539
uniprot id: A0A3P8WET5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

244447:LOC103381457
gene id: 244447:LOC103381457
uniprot id: A0A3P8VAU9
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. PHOSPHO family.

244447:LOC103379305
gene id: 244447:LOC103379305
uniprot id: A0A3P8VN80
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.

244447:ube2f
gene id: 244447:ube2f
uniprot id: A0A3P8WSM1
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

244447:znf592
gene id: 244447:znf592
uniprot id: A0A3P8W016
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the krueppel C2H2-type zinc-finger protein family.
messages: May be involved in transcriptional regulation.
messages: Nucleus

244447:LOC103396029
gene id: 244447:LOC103396029
uniprot id: A0A3P8WHU6
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a 'chicken-wire' meshwork together with laminins, proteoglycans and entactin/nidogen.
messages: basement membrane

244447:LOC103386866
gene id: 244447:LOC103386866
uniprot id: A0A3P8UJ93
uniprot id: A0A3P8UK88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. SLC8 subfamily.
messages: Cell membrane
messages: Membrane

244447:aspa
gene id: 244447:aspa
uniprot id: A0A3P8WAY7
names: Cofactor
names: Similarity
messages: Belongs to the AspA/AstE family. Aspartoacylase subfamily.
messages: Binds 1 zinc ion per subunit.

244447:slc25a32
gene id: 244447:slc25a32
uniprot id: A0A3P8W6M4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

244447:LOC103391543
gene id: 244447:LOC103391543
uniprot id: A0A3P8X546
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

244447:LOC103382249
gene id: 244447:LOC103382249
uniprot id: A0A3P8URQ1
names: Similarity
messages: Belongs to the histidine acid phosphatase family. MINPP1 subfamily.

244447:LOC103391014
gene id: 244447:LOC103391014
uniprot id: A0A3P8VXY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Nucleus

244447:nrf1
gene id: 244447:nrf1
uniprot id: A0A3P8VGR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NRF1/Ewg family.
messages: Nucleus

244447:LOC103383197
gene id: 244447:LOC103383197
uniprot id: A0A3P8WYF2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the V-ATPase e1/e2 subunit family.
messages: Membrane
messages: Subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.

244447:LOC103386024
gene id: 244447:LOC103386024
uniprot id: A0A3P8UJ45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C2 family.
messages: Cell membrane
messages: Cytoplasm
messages: Membrane

244447:pdyn
gene id: 244447:pdyn
uniprot id: A0A3P8UXT2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the opioid neuropeptide precursor family.
messages: Dynorphin peptides differentially regulate the kappa opioid receptor. Dynorphin A(1-13) has a typical opiod activity, it is 700 times more potent than Leu-enkephalin.
messages: Leu-enkephalins compete with and mimic the effects of opiate drugs. They play a role in a number of physiologic functions, including pain perception and responses to stress.
messages: Leumorphin has a typical opiod activity and may have anti-apoptotic effect.
messages: Secreted

244447:dpp3
gene id: 244447:dpp3
uniprot id: A0A3P8WVM3
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M49 family.
messages: Binds 1 zinc ion per subunit.

244447:ccnc
gene id: 244447:ccnc
uniprot id: A0A3P8WT56
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cyclin family. Cyclin AB subfamily.
messages: Belongs to the cyclin family. Cyclin C subfamily.
messages: Component of the Mediator complex, a coactivator involved in regulated gene transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. Binds to and activates cyclin-dependent kinase CDK8 that phosphorylates the CTD (C-terminal domain) of the large subunit of RNA polymerase II (RNAp II), which may inhibit the formation of a transcription initiation complex.
messages: Nucleus

244447:LOC103388495
gene id: 244447:LOC103388495
uniprot id: A0A3P8V8X3
names: Similarity
messages: Belongs to the protein kinase superfamily.

244447:LOC103392494
gene id: 244447:LOC103392494
uniprot id: A0A3P8WTM6
names: Subcellular Location Annotation
messages: Nucleus

244447:slc7a3
gene id: 244447:slc7a3
uniprot id: A0A3P8WQW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Cationic amino acid transporter (CAT) (TC 2.A.3.3) family.
messages: Cell membrane
messages: Membrane

244447:mettl16
gene id: 244447:mettl16
uniprot id: A0A3P8WQJ9
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. METTL16/RlmF family.
messages: RNA N6-methyltransferase that methylates adenosine residues at the N(6) position of a subset of RNAs and is involved in S-adenosyl-L-methionine homeostasis by regulating expression of MAT2A transcripts. Able to N6-methylate a subset of mRNAs and U6 small nuclear RNAs (U6 snRNAs). In contrast to the METTL3-METTL14 heterodimer, only able to methylate a limited number of RNAs: requires both a 5'UACAGAGAA-3' nonamer sequence and a specific RNA structure.

244447:arg2
gene id: 244447:arg2
uniprot id: A0A3P8VK33
names: Cofactor
names: Similarity
messages: Belongs to the arginase family.
messages: Binds 2 manganese ions per subunit.

244447:LOC103397050
gene id: 244447:LOC103397050
uniprot id: A0A3P8WUA4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AB hydrolase superfamily. Lipase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

244447:LOC103398401
gene id: 244447:LOC103398401
uniprot id: A0A3P8UBF8
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

244447:LOC103381643
gene id: 244447:LOC103381643
uniprot id: A0A3P8VRP5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase A22A family.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Homodimer.
messages: Membrane
messages: Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors.
messages: The PAL motif is required for normal active site conformation.

244447:nedd9
gene id: 244447:nedd9
uniprot id: A0A3P8VL95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAS family.
messages: focal adhesion

244447:ptpa
gene id: 244447:ptpa
uniprot id: A0A3P8WN87
uniprot id: A0A3P8WRR2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PTPA-type PPIase family.
messages: Cytoplasm
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

244447:LOC103383567
gene id: 244447:LOC103383567
uniprot id: A0A3P8UYG4
names: Subcellular Location Annotation
messages: Endosome membrane
messages: Membrane

244447:wls
gene id: 244447:wls
uniprot id: A0A3P8WTC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the wntless family.
messages: Golgi apparatus membrane
messages: Membrane

244447:nmd3
gene id: 244447:nmd3
uniprot id: A0A3P8WTZ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as an adapter for the XPO1/CRM1-mediated export of the 60S ribosomal subunit.
messages: Belongs to the NMD3 family.
messages: Cytoplasm
messages: Nucleus

244447:gpn2
gene id: 244447:gpn2
uniprot id: A0A3P8V530
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GPN-loop GTPase family.
messages: Binds to RNA polymerase II (RNAPII).
messages: Small GTPase required for proper localization of RNA polymerase II and III (RNAPII and RNAPIII). May act at an RNAP assembly step prior to nuclear import.

244447:LOC103381310
gene id: 244447:LOC103381310
uniprot id: A0A3P8UZL1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDC50/LEM3 family.
messages: Cell membrane
messages: Golgi apparatus
messages: Membrane
messages: secretory vesicle membrane

244447:cldn15
gene id: 244447:cldn15
uniprot id: A0A3P8V3E6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

244447:LOC103396208
gene id: 244447:LOC103396208
uniprot id: A0A3P8WVY0
names: Similarity
messages: Belongs to the GPSM family.

244447:acbd7
gene id: 244447:acbd7
uniprot id: A0A3P8UPR5
names: Similarity
messages: Belongs to the carnitine/choline acetyltransferase family.

244447:LOC103390247
gene id: 244447:LOC103390247
uniprot id: A0A3P8WTS5
names: Subcellular Location Annotation
messages: ruffle membrane

244447:LOC103377998
gene id: 244447:LOC103377998
uniprot id: A0A3P8VAM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRIM/RBCC family.
messages: Cytoplasm

244447:aspdh
gene id: 244447:aspdh
uniprot id: A0A3P8W4T9
names: Similarity
messages: Belongs to the L-aspartate dehydrogenase family.

244447:paip2b
gene id: 244447:paip2b
uniprot id: A0A3P8WH86
names: Similarity
messages: Belongs to the PAIP2 family.

244447:hdx
gene id: 244447:hdx
uniprot id: A0A3P8WNK0
names: Subcellular Location Annotation
messages: Nucleus

244447:srd5a3
gene id: 244447:srd5a3
uniprot id: A0A3P8UZ94
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Also able to convert testosterone (T) into 5-alpha-dihydrotestosterone (DHT).
messages: Belongs to the steroid 5-alpha reductase family. Polyprenol reductase subfamily.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Plays a key role in early steps of protein N-linked glycosylation by being required for the conversion of polyprenol into dolichol. Dolichols are required for the synthesis of dolichol-linked monosaccharides and the oligosaccharide precursor used for N-glycosylation. Acts as a polyprenol reductase that promotes the reduction of the alpha-isoprene unit of polyprenols into dolichols in a NADP-dependent mechanism.

244447:LOC103386479
gene id: 244447:LOC103386479
uniprot id: A0A3P8UFH0
names: Subcellular Location Annotation
messages: Nucleus

244447:LOC103389794
gene id: 244447:LOC103389794
uniprot id: A0A3P8W6U8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

244447:ppp2ca
gene id: 244447:ppp2ca
uniprot id: A0A3P8WDY0
names: Similarity
messages: Belongs to the PPP phosphatase family.

244447:LOC103389305
gene id: 244447:LOC103389305
uniprot id: A0A3P8UPQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

244447:LOC103393914
gene id: 244447:LOC103393914
uniprot id: A0A3P8VBE4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

244447:dxo
gene id: 244447:dxo
uniprot id: A0A3P8W7C9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DXO/Dom3Z family.
messages: Binds 2 magnesium ions.
messages: Decapping enzyme for NAD-capped RNAs: specifically hydrolyzes the nicotinamide adenine dinucleotide (NAD) cap from a subset of RNAs by removing the entire NAD moiety from the 5'-end of an NAD-capped RNA.
messages: Nucleus

244447:cdipt
gene id: 244447:cdipt
uniprot id: A0A3P8VV74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

244447:LOC103396649
gene id: 244447:LOC103396649
uniprot id: A0A3P8X0A3
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP, AMP, or fructose 2,6-bisphosphate, and allosterically inhibited by ATP or citrate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade "E" sub-subfamily.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homo- and heterotetramers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

244447:adra1d
gene id: 244447:adra1d
uniprot id: A0A3P8VJG1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Interacts with FLNA (via filamin repeat 21); increases PKA-mediated phosphorylation of FLNA.
messages: Membrane
messages: This alpha-adrenergic receptor mediates its effect through the influx of extracellular calcium.

244447:coq7
gene id: 244447:coq7
uniprot id: A0A3P8VSA2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the COQ7 family.
messages: Binds 2 iron ions per subunit.
messages: Catalyzes the hydroxylation of 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) during ubiquinone biosynthesis. Has also a structural role in the COQ enzyme complex, stabilizing other COQ polypeptides. Involved in lifespan determination in a ubiquinone-independent manner.
messages: Component of a multi-subunit COQ enzyme complex, composed of at least COQ3, COQ4, COQ5, COQ6, COQ7 and COQ9. Interacts with ADCK4 and COQ6. Interacts with COQ9.
messages: Mitochondrion inner membrane

244447:LOC103386112
gene id: 244447:LOC103386112
uniprot id: A0A3P8V332
names: Similarity
messages: Belongs to the intermediate filament family.

244447:rad9a
gene id: 244447:rad9a
uniprot id: A0A3P8V991
names: Similarity
messages: Belongs to the rad9 family.

244447:sybu
gene id: 244447:sybu
uniprot id: A0A3P8VMP7
names: Subcellular Location Annotation
messages: Membrane

244447:mrpl12
gene id: 244447:mrpl12
uniprot id: A0A3P8VGB2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL12 family.

244447:LOC103386478
gene id: 244447:LOC103386478
uniprot id: A0A3P8WC27
uniprot id: A0A3P8WC37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 3 family.
messages: Cell membrane
messages: Membrane

244447:LOC103388615
gene id: 244447:LOC103388615
uniprot id: A0A3P8VJB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

244447:met
gene id: 244447:met
uniprot id: A0A3P8X5G9
names: Caution
names: Subcellular Location Annotation
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

244447:fscn1
gene id: 244447:fscn1
uniprot id: A0A3P8WT08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fascin family.
messages: cytoskeleton

244447:LOC103384725
gene id: 244447:LOC103384725
uniprot id: A0A3P8UXF7
names: Similarity
messages: Belongs to the filamin family.

244447:LOC103393286
gene id: 244447:LOC103393286
uniprot id: A0A3P8V2X9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family.
messages: Nucleus

244447:api5
gene id: 244447:api5
uniprot id: A0A3P8UDB8
names: Similarity
messages: Belongs to the API5 family.

244447:LOC103396135
gene id: 244447:LOC103396135
uniprot id: A0A3P8WJF6
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

244447:LOC103378105
gene id: 244447:LOC103378105
uniprot id: A0A3P8VE50
names: Similarity
messages: Belongs to the 'GDXG' lipolytic enzyme family.

244447:LOC103388425
gene id: 244447:LOC103388425
uniprot id: A0A3P8UZZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus

244447:LOC103393517
gene id: 244447:LOC103393517
uniprot id: A0A3P8VZ18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily.
messages: Cell membrane
messages: Membrane

244447:LOC103394883
gene id: 244447:LOC103394883
uniprot id: A0A3P8WF01
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.

244447:garem2
gene id: 244447:garem2
uniprot id: A0A3P8USP3
names: Similarity
messages: Belongs to the GAREM family.

244447:slc25a11
gene id: 244447:slc25a11
uniprot id: A0A3P8V7L1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

244447:LOC103386715
gene id: 244447:LOC103386715
uniprot id: A0A3P8WSP2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAD-like hydrolase superfamily. EYA family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nucleus

244447:hagh
gene id: 244447:hagh
uniprot id: A0A3P8WGE5
names: Similarity
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.

244447:LOC103397699
gene id: 244447:LOC103397699
uniprot id: A0A3P8WI37
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.

244447:ip6k2
gene id: 244447:ip6k2
uniprot id: A0A3P8UNT2
names: Similarity
messages: Belongs to the inositol phosphokinase (IPK) family.

244447:hint1
gene id: 244447:hint1
uniprot id: A0A3P8UZB3
names: Similarity
messages: Belongs to the HINT family.

244447:tlr7
gene id: 244447:tlr7
uniprot id: A0A3P8VQU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Toll-like receptor family.
messages: Membrane

244447:LOC103389709
gene id: 244447:LOC103389709
uniprot id: A0A3P8VR69
uniprot id: A0A3P8VZ50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the interleukin-1 receptor family.
messages: Membrane

244447:LOC103394108
gene id: 244447:LOC103394108
uniprot id: A0A3P8VW05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the macoilin family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Nucleus membrane
messages: Rough endoplasmic reticulum membrane

244447:eif2ak3
gene id: 244447:eif2ak3
uniprot id: A0A3P8WHH0
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane

244447:LOC103380931
gene id: 244447:LOC103380931
uniprot id: A0A3P8X190
uniprot id: A0A3P8X5P1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

244447:foxf2
gene id: 244447:foxf2
uniprot id: A0A3P8VJA5
names: Subcellular Location Annotation
messages: Nucleus

244447:ccne1
gene id: 244447:ccne1
uniprot id: A0A3P8UIL1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cyclin family. Cyclin AB subfamily.
messages: Belongs to the cyclin family. Cyclin E subfamily.
messages: Essential for the control of the cell cycle at the G2/M (mitosis) transition.
messages: Interacts with the CDK1 protein kinase to form a serine/threonine kinase holoenzyme complex also known as maturation promoting factor (MPF). The cyclin subunit imparts substrate specificity to the complex.

244447:LOC103385773
gene id: 244447:LOC103385773
uniprot id: A0A3P8UHX5
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family.

244447:LOC103395851
gene id: 244447:LOC103395851
uniprot id: A0A3P8VUK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

244447:LOC103384911
gene id: 244447:LOC103384911
uniprot id: A0A3P8V0Q9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

244447:LOC112486239
gene id: 244447:LOC112486239
uniprot id: A0A3P8UBA0
names: Similarity
messages: Belongs to the TGF-beta family.

244447:LOC103390918
gene id: 244447:LOC103390918
uniprot id: A0A3P8VAK0
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

244447:LOC103378813
gene id: 244447:LOC103378813
uniprot id: A0A3P8UYC2
names: Subcellular Location Annotation
messages: extracellular space

244447:atp13a1
gene id: 244447:atp13a1
uniprot id: A0A3P8VTL1
names: Similarity
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily.

244447:LOC103383860
gene id: 244447:LOC103383860
uniprot id: A0A3P8VIR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HDGF family.
messages: Nucleus

244447:rps13
gene id: 244447:rps13
uniprot id: A0A3P8UDX5
names: Similarity
messages: Belongs to the universal ribosomal protein uS15 family.

244447:rrp7a
gene id: 244447:rrp7a
uniprot id: A0A3P8VFE3
names: Similarity
messages: Belongs to the RRP7 family.

244447:nr0b2
gene id: 244447:nr0b2
uniprot id: A0A3P8V0Y6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR0 subfamily.
messages: Cytoplasm
messages: Nucleus

244447:trappc9
gene id: 244447:trappc9
uniprot id: A0A3P8VGZ7
names: Similarity
messages: Belongs to the NIBP family.

244447:LOC103384935
gene id: 244447:LOC103384935
uniprot id: A0A3P8UY16
names: Similarity
messages: Belongs to the RimK family.

244447:LOC103391318
gene id: 244447:LOC103391318
uniprot id: A0A3P8W1K8
names: Similarity
messages: Belongs to the FMR1 family.

244447:crtc1
gene id: 244447:crtc1
uniprot id: A0A3P8WQM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TORC family.
messages: Cytoplasm
messages: Nucleus

244447:slc35a1
gene id: 244447:slc35a1
uniprot id: A0A3P8UUW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide-sugar transporter family. SLC35A subfamily.
messages: Membrane

244447:nle1
gene id: 244447:nle1
uniprot id: A0A3P8VPA1
names: Subcellular Location Annotation
messages: nucleolus

244447:LOC103384746
gene id: 244447:LOC103384746
uniprot id: A0A3P8UQW8
uniprot id: A0A3P8UUX1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone deacetylase family. HD type 2 subfamily.
messages: Nucleus
messages: Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.

244447:LOC103396662
gene id: 244447:LOC103396662
uniprot id: A0A3P8X0J0
uniprot id: A0A3P8X2Y6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC12A transporter family.
messages: Membrane

244447:hoxd12
gene id: 244447:hoxd12
uniprot id: A0A3P8V8I1
names: Subcellular Location Annotation
messages: Nucleus

244447:hebp1
gene id: 244447:hebp1
uniprot id: A0A3P8V9T2
names: Similarity
messages: Belongs to the HEBP family.

244447:LOC103378914
gene id: 244447:LOC103378914
uniprot id: A1YTL2
names: Similarity
messages: Belongs to the cytochrome P450 family.

244447:polr2c
gene id: 244447:polr2c
uniprot id: A0A3P8UHD0
names: Similarity
messages: Belongs to the archaeal Rpo3/eukaryotic RPB3 RNA polymerase subunit family.

244447:ess2
gene id: 244447:ess2
uniprot id: A0A3P8WEW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ESS2 family.
messages: Nucleus

244447:med17
gene id: 244447:med17
uniprot id: A0A3P8V3S1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 17 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

244447:slc10a1
gene id: 244447:slc10a1
uniprot id: A0A3P8UI19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bile acid:sodium symporter (BASS) (TC 2.A.28) family.
messages: Membrane

244447:ap1s3
gene id: 244447:ap1s3
uniprot id: A0A3P8UZ56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adaptor complexes small subunit family.
messages: Cytoplasmic vesicle membrane
messages: Golgi apparatus
messages: clathrin-coated pit

244447:pex14
gene id: 244447:pex14
uniprot id: A0A3P8UYU1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxin-14 family.
messages: Component of the peroxisomal translocation machinery.
messages: Peroxisome membrane

244447:mul1
gene id: 244447:mul1
uniprot id: A0A3P8WNF8
names: Subcellular Location Annotation
messages: Membrane

244447:ppie
gene id: 244447:ppie
uniprot id: A0A3P8UC79
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family. PPIase E subfamily.
messages: Catalyzes the cis-trans isomerization of proline imidic peptide bonds in proteins.

244447:tsen2
gene id: 244447:tsen2
uniprot id: A0A3P8WZ36
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA-intron endonuclease family.
messages: Constitutes one of the two catalytic subunit of the tRNA-splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3'-cyclic phosphate and 5'-OH termini. There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structural features of the tRNA body.
messages: Nucleus

244447:LOC103393152
gene id: 244447:LOC103393152
uniprot id: A0A3P8WR58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the actinoporin family. Sea anemone subfamily.
messages: Cell membrane
messages: Membrane
messages: Nematocyst
messages: Target cell membrane

244447:bloc1s5
gene id: 244447:bloc1s5
uniprot id: A0A3P8VKG5
names: Similarity
messages: Belongs to the BLOC1S5 family.

244447:blcap
gene id: 244447:blcap
uniprot id: A0A3P8W948
names: Similarity
messages: Belongs to the BLCAP family.

244447:LOC103397878
gene id: 244447:LOC103397878
uniprot id: A0A3P8UJB5
names: Subcellular Location Annotation
messages: Nucleus

244447:top1
gene id: 244447:top1
uniprot id: A0A3P8VLP9
names: Function
names: Similarity
messages: Belongs to the type IB topoisomerase family.
messages: Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus removing DNA supercoils. Finally, in the religation step, the DNA 5'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

244447:cygb
gene id: 244447:cygb
uniprot id: A0A3P8VI56
names: Similarity
messages: Belongs to the globin family.

244447:LOC103384330
gene id: 244447:LOC103384330
uniprot id: A0A3P8WEH3
names: Similarity
messages: Belongs to the cytochrome P450 family.

244447:cdh1
gene id: 244447:cdh1
uniprot id: A0A3P8WIB9
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane
messages: Membrane

244447:rag2
gene id: 244447:rag2
uniprot id: A0A3P8W1X3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RAG2 family.
messages: Nucleus

244447:LOC103385945
gene id: 244447:LOC103385945
uniprot id: A0A3P8UX59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. EGF receptor subfamily.
messages: Membrane

244447:adcy9
gene id: 244447:adcy9
uniprot id: A0A3P8WCZ0
uniprot id: A0A3P8WD00
uniprot id: A0A3P8WL23
names: Similarity
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.

244447:LOC103396046
gene id: 244447:LOC103396046
uniprot id: A0A3P8WFK3
uniprot id: A0A3P8WJ55
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

244447:LOC103391682
gene id: 244447:LOC103391682
uniprot id: A0A3P8W7L4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LAMP family.
messages: Endosome membrane

244447:LOC103394464
gene id: 244447:LOC103394464
uniprot id: A0A3P8WW67
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

244447:arf3
gene id: 244447:arf3
uniprot id: A0A3P8VFJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: GTP-binding protein involved in protein trafficking; modulates vesicle budding and uncoating within the Golgi apparatus.
messages: Golgi apparatus

244447:rbp5
gene id: 244447:rbp5
uniprot id: A0A3P8WUD3
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

244447:LOC103386594
gene id: 244447:LOC103386594
uniprot id: A0A3P8WNG0
names: Subcellular Location Annotation
messages: Nucleus

244447:LOC103377473
gene id: 244447:LOC103377473
uniprot id: A0A3P8UBY9
names: Similarity
messages: Belongs to the SNF7 family.

244447:LOC103382819
gene id: 244447:LOC103382819
uniprot id: A0A3P8VK64
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

244447:LOC103378502
gene id: 244447:LOC103378502
uniprot id: A0A3P8WPI3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the organo anion transporter (TC 2.A.60) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

244447:fam206a
gene id: 244447:fam206a
uniprot id: A0A3P8VCI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABITRAM family.
messages: growth cone
messages: lamellipodium

244447:LOC103378982
gene id: 244447:LOC103378982
uniprot id: A0A3P8VCR0
names: Similarity
messages: Belongs to the pyruvate kinase family.

244447:zup1
gene id: 244447:zup1
uniprot id: A0A3P8VPU5
names: Similarity
names: Subunit
messages: Belongs to the peptidase C78 family. ZUFSP subfamily.
messages: Interacts with RPA1 and RPA2.

244447:LOC103388645
gene id: 244447:LOC103388645
uniprot id: A0A3P8VH06
names: Function
names: Similarity
messages: Belongs to the RutC family.
messages: Catalyzes the hydrolytic deamination of enamine/imine intermediates that form during the course of normal metabolism. May facilitate the release of ammonia from these potentially toxic reactive metabolites, reducing their impact on cellular components. It may act on enamine/imine intermediates formed by several types of pyridoxal-5'-phosphate-dependent dehydratases including L-threonine dehydratase.

244447:LOC103397063
gene id: 244447:LOC103397063
uniprot id: A0A3P8VVN1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transcriptional coactivator PC4 family.
messages: General coactivator that functions cooperatively with TAFs and mediates functional interactions between upstream activators and the general transcriptional machinery. May be involved in stabilizing the multiprotein transcription complex. Binds single-stranded DNA. Also binds, in vitro, non-specifically to double-stranded DNA (ds DNA).
messages: Nucleus

244447:LOC103391284
gene id: 244447:LOC103391284
uniprot id: A0A3P8WK16
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mo25 family.
messages: Component of a complex that binds and activates STK11/LKB1. In the complex, required to stabilize the interaction between CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta) and STK11/LKB1.
messages: Component of a trimeric complex composed of STK11/LKB1, STRAD (STRADA or STRADB) and CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta): the complex tethers STK11/LKB1 in the cytoplasm and stimulates its catalytic activity.

244447:LOC103386708
gene id: 244447:LOC103386708
uniprot id: A0A3P8WSB0
names: Subcellular Location Annotation
messages: extracellular space

244447:LOC103394723
gene id: 244447:LOC103394723
uniprot id: A0A3P8VMU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GRB7/10/14 family.
messages: Cytoplasm

244447:efnb1
gene id: 244447:efnb1
uniprot id: A0A3P8WDY6
names: Caution
names: Similarity
messages: Belongs to the ephrin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

244447:LOC103388311
gene id: 244447:LOC103388311
uniprot id: A0A3P8UYB9
names: Subcellular Location Annotation
messages: Membrane

244447:LOC103387490
gene id: 244447:LOC103387490
uniprot id: A0A3P8VFZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BORG/CEP family.
messages: Endomembrane system

244447:yipf6
gene id: 244447:yipf6
uniprot id: A0A3P8W0W2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YIP1 family.
messages: Membrane

244447:rps11
gene id: 244447:rps11
uniprot id: A0A3P8X593
names: Similarity
messages: Belongs to the universal ribosomal protein uS17 family.

244447:p2rx2
gene id: 244447:p2rx2
uniprot id: A0A3P8WME9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the P2X receptor family.
messages: Functional P2XRs are organized as homomeric and heteromeric trimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Receptor for ATP that acts as a ligand-gated ion channel.

244447:copa
gene id: 244447:copa
uniprot id: A0A3P8X5D5
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Membrane
messages: Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.
messages: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated to ADP-ribosylation factors (ARFs), which are small GTP-binding proteins; the complex also influences the Golgi structural integrity, as well as the processing, activity, and endocytic recycling of LDL receptors.

244447:LOC103388099
gene id: 244447:LOC103388099
uniprot id: A0A3P8UF15
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

244447:pabpc1
gene id: 244447:pabpc1
uniprot id: A0A3P8W8J4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyadenylate-binding protein type-1 family.
messages: Binds the poly(A) tail of mRNA.
messages: Cytoplasm

244447:LOC103381117
gene id: 244447:LOC103381117
uniprot id: A0A0U2X3U5
names: Similarity
messages: Belongs to the Toll-like receptor family.

244447:tmed2
gene id: 244447:tmed2
uniprot id: A0A3P8W378
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Membrane
messages: cis-Golgi network membrane

244447:cnih1
gene id: 244447:cnih1
uniprot id: A0A3P8VDX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cornichon family.
messages: Membrane

244447:snx18
gene id: 244447:snx18
uniprot id: A0A3P8X148
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Cytoplasmic vesicle membrane

244447:susd2
gene id: 244447:susd2
uniprot id: A0A3P8WDB0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

244447:LOC103388296
gene id: 244447:LOC103388296
uniprot id: A0A3P8UYA9
uniprot id: A0A3P8UZU8
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

244447:mcu
gene id: 244447:mcu
uniprot id: A0A3P8VWR2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCU (TC 1.A.77) family.
messages: Forms a well-packed pentamer with an overall cylindrical shape. The inner core of the pentamer is formed with the second transmembrane region and the second coiled-coil region: while the transmembrane regions pack into a five-helix bundle having a largely polar pore across the membrane, the coiled-coil outside the membrane forms a pentamer with a hydrophobic core. The inner core is wrapped by the first transmembrane region through contacts between the first and the second transmembrane regions. The second transmembrane is followed by the inner juxtamembrane region (IJMH) that orients at a wide angle relative to the second transmembrane. The two core domains are held together on the periphery by the outer juxtamembrane helix (OJMH).
messages: Membrane
messages: Mitochondrial inner membrane calcium uniporter that mediates calcium uptake into mitochondria. Constitutes a pore-forming and calcium-conducting subunit. Mitochondrial calcium homeostasis plays key roles in cellular physiology and regulates cell bioenergetics, cytoplasmic calcium signals and activation of cell death pathways.
messages: Mitochondrion inner membrane

244447:znrd1
gene id: 244447:znrd1
uniprot id: A0A3P8V384
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.
messages: Component of the RNA polymerase I (Pol I) complex consisting of at least 13 subunits.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase I which synthesizes ribosomal RNA precursors.
messages: nucleolus

244447:LOC103397868
gene id: 244447:LOC103397868
uniprot id: A0A3P8UAQ9
names: Subcellular Location Annotation
messages: Nucleus

244447:xylt2
gene id: 244447:xylt2
uniprot id: A0A3P8WQK5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycosyltransferase 14 family. XylT subfamily.
messages: Golgi apparatus membrane
messages: Membrane
messages: Monomer.

244447:LOC103387686
gene id: 244447:LOC103387686
uniprot id: A0A3P8WF98
uniprot id: A0A3P8WL49
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine-phosphorylated proteins. Also acts as a lipid phosphatase, removing the phosphate in the D3 position of the inositol ring from phosphatidylinositol 3,4,5-trisphosphate, phosphatidylinositol 3,4-diphosphate, phosphatidylinositol 3-phosphate and inositol 1,3,4,5-tetrakisphosphate with order of substrate preference in vitro PtdIns(3,4,5)P3 > PtdIns(3,4)P2 > PtdIns3P > Ins(1,3,4,5)P4.
messages: Belongs to the PTEN phosphatase protein family.
messages: Cytoplasm
messages: Nucleus
messages: PML body
messages: Postsynaptic density
messages: dendritic spine

244447:LOC103394467
gene id: 244447:LOC103394467
uniprot id: A0A3P8WWH0
names: Similarity
messages: Belongs to the protein kinase superfamily.

244447:aptx
gene id: 244447:aptx
uniprot id: A0A3P8VQW4
names: Subcellular Location Annotation
messages: nucleolus
messages: nucleoplasm

244447:zdhhc4
gene id: 244447:zdhhc4
uniprot id: A0A3P8UHQ9
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

244447:podxl
gene id: 244447:podxl
uniprot id: A0A3P8UPD6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the podocalyxin family.
messages: Cell membrane
messages: Membrane
messages: Membrane raft
messages: filopodium
messages: lamellipodium
messages: microvillus
messages: ruffle

244447:tspan11
gene id: 244447:tspan11
uniprot id: A0A3P8VKJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

244447:LOC103393918
gene id: 244447:LOC103393918
uniprot id: A0A3P8VK02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Cell membrane
messages: Membrane

244447:psme4
gene id: 244447:psme4
uniprot id: A0A3P8V5W1
names: Similarity
messages: Belongs to the BLM10 family.

244447:LOC103378390
gene id: 244447:LOC103378390
uniprot id: A0A3P8WC32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STOP family.
messages: cytoskeleton

244447:kif1c
gene id: 244447:kif1c
uniprot id: A0A3P8V2F5
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

244447:LOC103379200
gene id: 244447:LOC103379200
uniprot id: A0A3P8UQP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CART family.
messages: Secreted

244447:ano7
gene id: 244447:ano7
uniprot id: A0A3P8WCW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anoctamin family.
messages: Membrane

244447:ttc21b
gene id: 244447:ttc21b
uniprot id: A0A3P8VGG3
names: Similarity
messages: Belongs to the TTC21 family.

244447:phb2
gene id: 244447:phb2
uniprot id: A0A3P8WUX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prohibitin family.
messages: Cell membrane
messages: Mitochondrion inner membrane

244447:cltrn
gene id: 244447:cltrn
uniprot id: A0A3P8X0M0
names: Subcellular Location Annotation
messages: Membrane

244447:slitrk1
gene id: 244447:slitrk1
uniprot id: A0A3P8VQE9
names: Similarity
messages: Belongs to the SLITRK family.

244447:pold2
gene id: 244447:pold2
uniprot id: A0A3P8VTI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase delta/II small subunit family.
messages: Nucleus

244447:jpt1
gene id: 244447:jpt1
uniprot id: A0A3P8W5N5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the JUPITER family.
messages: Cytoplasm
messages: Nucleus

244447:LOC103391202
gene id: 244447:LOC103391202
uniprot id: A0A3P8WFQ2
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

244447:nkd2
gene id: 244447:nkd2
uniprot id: A0A3P8V1I6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NKD family.
messages: Cell autonomous antagonist of the canonical Wnt signaling pathway.
messages: Cell membrane
messages: Cytoplasm
messages: Membrane

244447:LOC103391208
gene id: 244447:LOC103391208
uniprot id: A0A3P8W9H3
names: Similarity
messages: Belongs to the PPP phosphatase family.

244447:panx3
gene id: 244447:panx3
uniprot id: A0A3P8WNE2
uniprot id: A0A3P8WQW5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pannexin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Structural component of the gap junctions and the hemichannels.
messages: gap junction

244447:LOC103391785
gene id: 244447:LOC103391785
uniprot id: A0A3P8V3M6
names: Similarity
messages: Belongs to the CDC50/LEM3 family.

244447:tbrg1
gene id: 244447:tbrg1
uniprot id: A0A3P8USP5
uniprot id: A0A3P8UU08
names: Subcellular Location Annotation
messages: Nucleus

244447:sepsecs
gene id: 244447:sepsecs
uniprot id: A0A3P8VCE8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SepSecS family.
messages: Converts O-phosphoseryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.
messages: Cytoplasm
messages: Homotetramer formed by a catalytic dimer and a non-catalytic dimer serving as a binding platform that orients tRNASec for catalysis. Each tetramer binds the CCA ends of two tRNAs which point to the active sites of the catalytic dimer.

244447:KEH01 p09
gene id: 244447:KEH01_p09
uniprot id: C5H0F7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase protein 8 family.
messages: Membrane
messages: Mitochondrion membrane

244447:arl6
gene id: 244447:arl6
uniprot id: A0A3P8V382
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: cilium membrane

244447:LOC103397072
gene id: 244447:LOC103397072
uniprot id: A0A3P8VTD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMIM15 family.
messages: Membrane

244447:tacr3
gene id: 244447:tacr3
uniprot id: A0A3P8VK32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

244447:fam83b
gene id: 244447:fam83b
uniprot id: A0A3P8VNV8
names: Similarity
messages: Belongs to the FAM83 family.

244447:ascc3
gene id: 244447:ascc3
uniprot id: A0A3P8W0L8
names: Similarity
messages: Belongs to the helicase family.

244447:mogs
gene id: 244447:mogs
uniprot id: A0A3P8UQ27
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 63 family.
messages: Cleaves the distal alpha 1,2-linked glucose residue from the Glc(3)Man(9)GlcNAc(2) oligosaccharide precursor.
messages: Endoplasmic reticulum membrane

244447:LOC103394983
gene id: 244447:LOC103394983
uniprot id: A0A3P8WJY6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAIF1 family.
messages: Induces apoptosis.
messages: Nucleus

244447:creld1
gene id: 244447:creld1
uniprot id: A0A3P8X4W4
names: Caution
names: Similarity
messages: Belongs to the CRELD family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

244447:LOC103378086
gene id: 244447:LOC103378086
uniprot id: A0A3P8VJK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

244447:LOC103390286
gene id: 244447:LOC103390286
uniprot id: A0A3P8WUJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synuclein family.
messages: Membrane
messages: Nucleus
messages: Secreted
messages: Synapse

244447:LOC103389603
gene id: 244447:LOC103389603
uniprot id: A0A3P8V681
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

244447:LOC103386555
gene id: 244447:LOC103386555
uniprot id: A0A3P8WCT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

244447:LOC103379424
gene id: 244447:LOC103379424
uniprot id: A0A3P8W7K5
names: Similarity
messages: Belongs to the Bcl-2 family.

244447:ube2a
gene id: 244447:ube2a
uniprot id: A0A3P8UL13
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

244447:LOC103384113
gene id: 244447:LOC103384113
uniprot id: A0A3P8VZ05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NTE family.
messages: Endoplasmic reticulum membrane
messages: Membrane

244447:stk17b
gene id: 244447:stk17b
uniprot id: A0A3P8WG64
names: Similarity
messages: Belongs to the protein kinase superfamily.

244447:LOC103389110
gene id: 244447:LOC103389110
uniprot id: A0A3P8WJS5
names: Similarity
messages: In the N-terminal section; belongs to the AlaDH/PNT family.

244447:LOC103397597
gene id: 244447:LOC103397597
uniprot id: A0A3P8WQP1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

244447:LOC103394750
gene id: 244447:LOC103394750
uniprot id: A0A3P8VYB1
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

244447:LOC103387766
gene id: 244447:LOC103387766
uniprot id: A0A3P8WLS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family.
messages: Membrane

244447:yrdc
gene id: 244447:yrdc
uniprot id: A0A3P8WYG5
names: Similarity
messages: Belongs to the SUA5 family.

244447:pcca
gene id: 244447:pcca
uniprot id: A0A3P8WKM9
names: Subcellular Location Annotation
messages: Mitochondrion matrix

244447:npb
gene id: 244447:npb
uniprot id: A0A3P8VEH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neuropeptide B/W family.
messages: Secreted

244447:tomm22
gene id: 244447:tomm22
uniprot id: A0A3P8WVJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tom22 family.
messages: Mitochondrion outer membrane

244447:stoml2
gene id: 244447:stoml2
uniprot id: A0A3P8WY89
names: Similarity
messages: Belongs to the band 7/mec-2 family.

244447:psmb8
gene id: 244447:psmb8
uniprot id: A0A3P8WT67
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome complex.
messages: Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
messages: Cytoplasm
messages: Nucleus
messages: The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. This subunit is involved in antigen processing to generate class I binding peptides.

244447:LOC103380007
gene id: 244447:LOC103380007
uniprot id: A0A3P8USX5
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.

244447:LOC103391406
gene id: 244447:LOC103391406
uniprot id: A0A3P8WUL0
uniprot id: A0A3P8WWG3
names: Similarity
messages: Belongs to the phosphatase 2A regulatory subunit B family.

244447:LOC103382033
gene id: 244447:LOC103382033
uniprot id: A0A4P8CZN2
names: Subcellular Location Annotation
messages: Membrane

244447:LOC103392922
gene id: 244447:LOC103392922
uniprot id: A0A3P8W0Q3
uniprot id: A0A3P8W0V2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial Rho GTPase family.
messages: Membrane
messages: Mitochondrial GTPase involved in mitochondrial trafficking.
messages: Mitochondrion outer membrane

244447:mrpl15
gene id: 244447:mrpl15
uniprot id: A0A3P8WUS7
names: Similarity
messages: Belongs to the universal ribosomal protein uL15 family.

244447:toe1
gene id: 244447:toe1
uniprot id: A0A3P8X309
names: Similarity
messages: Belongs to the CAF1 family.

244447:LOC103389677
gene id: 244447:LOC103389677
uniprot id: A0A3P8VGG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XK family.
messages: Membrane

244447:plcb4
gene id: 244447:plcb4
uniprot id: A0A3P8ULJ8
names: Function
messages: The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.

244447:nppc
gene id: 244447:nppc
uniprot id: A0A3P8WAE1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the natriuretic peptide family.
messages: Secreted

244447:LOC103382347
gene id: 244447:LOC103382347
uniprot id: A0A3P8UGL7
names: Function
names: Similarity
messages: Belongs to the parvalbumin family.
messages: In muscle, parvalbumin is thought to be involved in relaxation after contraction. It binds two calcium ions.

244447:timm10
gene id: 244447:timm10
uniprot id: A0A3P8WA57
names: Function
messages: Mitochondrial intermembrane chaperone that participates in the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. May also be required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.

244447:LOC103379954
gene id: 244447:LOC103379954
uniprot id: A0A3P8UJX1
names: Similarity
messages: Belongs to the CD225/Dispanin family.

244447:tpk1
gene id: 244447:tpk1
uniprot id: A0A3P8VGI7
names: Similarity
messages: Belongs to the thiamine pyrophosphokinase family.

244447:pgm2l1
gene id: 244447:pgm2l1
uniprot id: A0A3P8V230
names: Similarity
messages: Belongs to the phosphohexose mutase family.

244447:manbal
gene id: 244447:manbal
uniprot id: A0A3P8WWR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0239 family.
messages: Membrane

244447:ostc
gene id: 244447:ostc
uniprot id: A0A3P8VA63
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OSTC family.
messages: Component of the oligosaccharyltransferase (OST) complex.
messages: Membrane
messages: Specific component of the STT3A-containing form of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity.

244447:LOC103392089
gene id: 244447:LOC103392089
uniprot id: A0A3P8VS06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM198 family.
messages: Membrane

244447:LOC103378224
gene id: 244447:LOC103378224
uniprot id: A0A3P8W5T0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/MEIS homeobox family.
messages: Nucleus

244447:LOC103383832
gene id: 244447:LOC103383832
uniprot id: A0A3P8VKL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat SMU1 family.
messages: Nucleus speckle

244447:hoxc12
gene id: 244447:hoxc12
uniprot id: A0A3P8VIT0
names: Subcellular Location Annotation
messages: Nucleus

244447:LOC103381165
gene id: 244447:LOC103381165
uniprot id: A0A3P8VJU9
names: Function
names: Subcellular Location Annotation
messages: Required for recruitment of CENPA to centromeres and normal chromosome segregation during mitosis.
messages: centromere

244447:ddx54
gene id: 244447:ddx54
uniprot id: A0A3P8WH51
names: Similarity
messages: Belongs to the DEAD box helicase family. DDX54/DBP10 subfamily.

244447:LOC103378134
gene id: 244447:LOC103378134
uniprot id: A0A3P8VLL2
names: Similarity
messages: Belongs to the FAM98 family.

244447:LOC103384558
gene id: 244447:LOC103384558
uniprot id: A0A3P8UF48
names: Similarity
messages: Belongs to the Nav/unc-53 family.

244447:grik1
gene id: 244447:grik1
uniprot id: A0A3P8VV30
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

244447:LOC103394701
gene id: 244447:LOC103394701
uniprot id: A0A3P8VNZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

244447:LOC103387870
gene id: 244447:LOC103387870
uniprot id: A0A3P8WS91
names: Similarity
messages: Belongs to the EVA1 family.

244447:sat1
gene id: 244447:sat1
uniprot id: A0A3P8WCG0
names: Similarity
names: Subunit
messages: Belongs to the acetyltransferase family.
messages: Homodimer.

244447:txlna
gene id: 244447:txlna
uniprot id: A0A3P8VM60
names: Similarity
messages: Belongs to the taxilin family.

244447:scn3b
gene id: 244447:scn3b
uniprot id: A0A3P8WGL6
uniprot id: A0A3P8WMH8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium channel auxiliary subunit SCN3B (TC 8.A.17) family.
messages: Membrane
messages: Modulates channel gating kinetics. Causes unique persistent sodium currents. Inactivates the sodium channel opening more slowly than the subunit beta-1. Its association with NFASC may target the sodium channels to the nodes of Ranvier of developing axons and retain these channels at the nodes in mature myelinated axons.

244447:LOC103381827
gene id: 244447:LOC103381827
uniprot id: A0A3P8W6R8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.
messages: Synaptic cell membrane

244447:LOC103388717
gene id: 244447:LOC103388717
uniprot id: A0A3P8VU34
names: Similarity
messages: Belongs to the dysbindin family.

244447:LOC103379093
gene id: 244447:LOC103379093
uniprot id: A0A3P8W049
names: Similarity
messages: In the N-terminal section; belongs to the AlaDH/PNT family.

244447:LOC103397166
gene id: 244447:LOC103397166
uniprot id: A0A3P8W1R8
names: Similarity
messages: Belongs to the BACURD family.

244447:slc25a22
gene id: 244447:slc25a22
uniprot id: A0A3P8VD10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

244447:LOC103390502
gene id: 244447:LOC103390502
uniprot id: A0A3P8UI80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

244447:hmces
gene id: 244447:hmces
uniprot id: A0A3P8V7J6
names: Function
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.
messages: Sensor of abasic sites in single-stranded DNA (ssDNA) required to preserve genome integrity by promoting error-free repair of abasic sites. Acts as an enzyme that recognizes and binds abasic sites in ssDNA at replication forks and chemically modifies the lesion by forming a covalent cross-link with DNA: forms a stable thiazolidine linkage between a ring-opened abasic site and the alpha-amino and sulfhydryl substituents of its N-terminal catalytic cysteine residue. The HMCES DNA-protein cross-link is then degraded by the proteasome. Promotes error-free repair of abasic sites by acting as a 'suicide' enzyme that is degraded, thereby protecting abasic sites from translesion synthesis (TLS) polymerases and endonucleases that are error-prone and would generate mutations and double-strand breaks. Has preference for ssDNA, but can also accommodate double-stranded DNA with 3' or 5' overhang (dsDNA), and dsDNA-ssDNA 3' junction.

244447:apopt1
gene id: 244447:apopt1
uniprot id: A0A3P8W1V2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COA8 family.
messages: Mitochondrion inner membrane

244447:nipbl
gene id: 244447:nipbl
uniprot id: A0A3P8W2M9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCC2/Nipped-B family.
messages: Nucleus

244447:irf1
gene id: 244447:irf1
uniprot id: I3QDC7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IRF family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

244447:bdnf
gene id: 244447:bdnf
uniprot id: A0A3P8UJE8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NGF-beta family.
messages: Promotes the survival of neuronal populations that are all located either in the central nervous system or directly connected to it.
messages: Secreted

244447:ppp1cb
gene id: 244447:ppp1cb
uniprot id: A0A3P8UVZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PPP phosphatase family. PP-1 subfamily.
messages: Cytoplasm

244447:LOC103389557
gene id: 244447:LOC103389557
uniprot id: A0A3P8V9T6
names: Similarity
messages: Belongs to the RAMP family.

244447:maf
gene id: 244447:maf
uniprot id: A0A3P8WBS7
names: Similarity
messages: Belongs to the bZIP family. Maf subfamily.

244447:pck1
gene id: 244447:pck1
uniprot id: A0A3P8X3E0
names: Similarity
messages: Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.

244447:eaf1
gene id: 244447:eaf1
uniprot id: A0A3P8VQ43
names: Similarity
messages: Belongs to the EAF family.

244447:LOC103386868
gene id: 244447:LOC103386868
uniprot id: A0A3P8UJC1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CNRIP family.
messages: Interacts with the cannabinoid receptor CNR1 (via C-terminus). Does not interact with cannabinoid receptor CNR2.
messages: Suppresses cannabinoid receptor CNR1-mediated tonic inhibition of voltage-gated calcium channels.

244447:LOC103392804
gene id: 244447:LOC103392804
uniprot id: A0A3P8VRW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP23 family.
messages: Membrane

244447:LOC103396268
gene id: 244447:LOC103396268
uniprot id: A0A3P8VLF4
names: Subcellular Location Annotation
messages: extracellular space

244447:esyt3
gene id: 244447:esyt3
uniprot id: A0A3P8WMR4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the extended synaptotagmin family.
messages: Cell membrane
messages: Endoplasmic reticulum membrane
messages: Membrane

244447:LOC103380989
gene id: 244447:LOC103380989
uniprot id: A0A3P8UQP2
names: Similarity
messages: Belongs to the heat shock protein 90 family.

244447:LOC103392744
gene id: 244447:LOC103392744
uniprot id: A0A3P8VQN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

244447:vopp1
gene id: 244447:vopp1
uniprot id: A0A3P8VFM3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VOPP1/ECOP family.
messages: Cytoplasmic vesicle membrane
messages: Membrane

244447:selenbp1
gene id: 244447:selenbp1
uniprot id: A0A3P8WYC4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the selenium-binding protein family.
messages: Catalyzes the oxidation of methanethiol, an organosulfur compound known to be produced in substantial amounts by gut bacteria. Selenium-binding protein which may be involved in the sensing of reactive xenobiotics in the cytoplasm. May be involved in intra-Golgi protein transport.
messages: Membrane
messages: Nucleus
messages: cytosol

244447:sele
gene id: 244447:sele
uniprot id: A0A3P8UAN0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the selectin/LECAM family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

244447:LOC103380116
gene id: 244447:LOC103380116
uniprot id: A0A3P8V0Z3
names: Subcellular Location Annotation
messages: Membrane

244447:tbce
gene id: 244447:tbce
uniprot id: A0A3P8UGB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TBCE family.
messages: Cytoplasm

244447:mettl26
gene id: 244447:mettl26
uniprot id: A0A3P8VQG6
names: Similarity
messages: Belongs to the UPF0585 family.

244447:pltp
gene id: 244447:pltp
uniprot id: A0A3P8WY30
names: Similarity
messages: Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family.

244447:LOC103390338
gene id: 244447:LOC103390338
uniprot id: A0A3P8X1U0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Cytoplasmic vesicle membrane

244447:nup50
gene id: 244447:nup50
uniprot id: A0A3P8UZN0
names: Subcellular Location Annotation
messages: nuclear pore complex

244447:cdh2
gene id: 244447:cdh2
uniprot id: A0A3P8VTE8
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane
messages: Membrane

244447:LOC103386554
gene id: 244447:LOC103386554
uniprot id: A0A3P8WC60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

244447:slc25a24
gene id: 244447:slc25a24
uniprot id: A0A3P8WS66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

244447:adam23
gene id: 244447:adam23
uniprot id: A0A3P8UMY7
uniprot id: A0A3P8UV17
uniprot id: A0A3P8UWJ9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

244447:myo1e
gene id: 244447:myo1e
uniprot id: A0A3P8UJC4
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

244447:LOC103392082
gene id: 244447:LOC103392082
uniprot id: A0A3P8VSH2
uniprot id: A0A3P8VVB5
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

244447:bcas2
gene id: 244447:bcas2
uniprot id: A0A3P8V3P8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPF27 family.
messages: Nucleus

244447:pnpo
gene id: 244447:pnpo
uniprot id: A0A3P8WBR8
names: Function
names: Similarity
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).

244447:fopnl
gene id: 244447:fopnl
uniprot id: A0A3P8W0B6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CEP43 family.
messages: cilium basal body

244447:gnas
gene id: 244447:gnas
uniprot id: A0A3P8WVI7
names: Similarity
messages: Belongs to the G-alpha family. G(s) subfamily.

244447:gps1
gene id: 244447:gps1
uniprot id: A0A3P8X2Z4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSN1 family.
messages: Cytoplasm
messages: Nucleus

244447:LOC103394220
gene id: 244447:LOC103394220
uniprot id: A0A3P8W990
names: Similarity
messages: Belongs to the OSBP family.

244447:LOC103391544
gene id: 244447:LOC103391544
uniprot id: A0A3P8WYA7
names: Subcellular Location Annotation
messages: Membrane

244447:LOC103376865
gene id: 244447:LOC103376865
uniprot id: A0A3P8VES7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c-type heme lyase family.
messages: Lyase that catalyzes the covalent linking of the heme group to the cytochrome C apoprotein to produce the mature functional cytochrome.
messages: Membrane
messages: Mitochondrion inner membrane

244447:LOC103397961
gene id: 244447:LOC103397961
uniprot id: A0A3P8UAM4
uniprot id: A0A3P8UI84
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the selectin/LECAM family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

244447:dbx2
gene id: 244447:dbx2
uniprot id: A0A3P8VGB6
names: Subcellular Location Annotation
messages: Nucleus

244447:LOC103386688
gene id: 244447:LOC103386688
uniprot id: A0A3P8WRA3
names: Similarity
messages: Belongs to the G-alpha family. G(s) subfamily.

244447:vrtn
gene id: 244447:vrtn
uniprot id: A0A3P8UE40
names: Similarity
messages: Belongs to the vertnin family.

244447:def8
gene id: 244447:def8
uniprot id: A0A3P8WCD3
names: Similarity
messages: Belongs to the DEF8 family.

244447:nhsl1
gene id: 244447:nhsl1
uniprot id: A0A3P8WXV4
uniprot id: A0A3P8WZP4
uniprot id: A0A3P8X082
names: Similarity
messages: Belongs to the NHS family.

244447:kri1
gene id: 244447:kri1
uniprot id: A0A3P8W915
names: Similarity
messages: Belongs to the KRI1 family.

244447:slc12a6
gene id: 244447:slc12a6
uniprot id: A0A3P8WLT7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC12A transporter family.
messages: Membrane

244447:tmem165
gene id: 244447:tmem165
uniprot id: A0A3P8UXQ7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GDT1 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

244447:LOC103380944
gene id: 244447:LOC103380944
uniprot id: A0A3P8X109
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MRAP family.
messages: Endoplasmic reticulum membrane
messages: Membrane

244447:rbm8a
gene id: 244447:rbm8a
uniprot id: A0A3P8W1T4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RBM8A family.
messages: Core component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junctions on mRNAs.
messages: Cytoplasm
messages: Heterodimer with MAGOH. Part of the mRNA splicing-dependent exon junction complex (EJC) complex; the core complex contains CASC3, EIF4A3, MAGOH and RBM8A.
messages: Nucleus
messages: Nucleus speckle

244447:kcnc1
gene id: 244447:kcnc1
uniprot id: A0A3P8VBY2
uniprot id: A0A3P8VBY4
names: Subcellular Location Annotation
messages: Membrane

244447:hprt1
gene id: 244447:hprt1
uniprot id: A0A3P8WQA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

244447:nhp2
gene id: 244447:nhp2
uniprot id: A0A3P8V8T3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic ribosomal protein eL8 family.
messages: Common component of the spliceosome and rRNA processing machinery.
messages: nucleolus

244447:atg101
gene id: 244447:atg101
uniprot id: A0A3P8VZ03
names: Similarity
messages: Belongs to the ATG101 family.

244447:hpgd
gene id: 244447:hpgd
uniprot id: A0A3P8WF56
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

244447:LOC103398274
gene id: 244447:LOC103398274
uniprot id: A0A3P8WD91
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.

244447:slc25a33
gene id: 244447:slc25a33
uniprot id: A0A3P8VD49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

244447:gdf3
gene id: 244447:gdf3
uniprot id: A0A3P8V7X4
names: Similarity
messages: Belongs to the TGF-beta family.

244447:sgtb
gene id: 244447:sgtb
uniprot id: A0A3P8W271
names: Similarity
messages: Belongs to the SGT family.

244447:thg1l
gene id: 244447:thg1l
uniprot id: A0A3P8WX75
names: Cofactor
names: Function
names: Similarity
messages: Adds a GMP to the 5'-end of tRNA(His) after transcription and RNase P cleavage.
messages: Belongs to the tRNA(His) guanylyltransferase family.
messages: Binds 2 magnesium ions per subunit.

244447:myd88
gene id: 244447:myd88
uniprot id: D2DF14
names: Function
names: Subcellular Location Annotation
messages: Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.
messages: Cytoplasm

244447:c6h11orf49
gene id: 244447:c6h11orf49
uniprot id: A0A3P8X3I5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSTPP1 family.
messages: centriolar satellite

244447:ccdc130
gene id: 244447:ccdc130
uniprot id: A0A3P8X3X2
names: Similarity
messages: Belongs to the CWC16 family.

244447:LOC103388613
gene id: 244447:LOC103388613
uniprot id: A0A3P8VQ16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the rad21 family.
messages: Nucleus

244447:tmem267
gene id: 244447:tmem267
uniprot id: A0A3P8WWN6
names: Subcellular Location Annotation
messages: Membrane

244447:ap1m1
gene id: 244447:ap1m1
uniprot id: A0A3P8WFU8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adaptor complexes medium subunit family.
messages: Golgi apparatus
messages: Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules.
messages: clathrin-coated vesicle membrane

244447:LOC103387312
gene id: 244447:LOC103387312
uniprot id: A0A3P8V7T9
names: Similarity
messages: Belongs to the FAM178 family.

244447:bysl
gene id: 244447:bysl
uniprot id: A0A3P8UJQ6
uniprot id: A0A3P8URU9
names: Similarity
messages: Belongs to the bystin family.

244447:twsg1
gene id: 244447:twsg1
uniprot id: A0A3P8WHQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the twisted gastrulation protein family.
messages: Secreted

244447:ap4b1
gene id: 244447:ap4b1
uniprot id: A0A3P8UWL8
names: Similarity
messages: Belongs to the adaptor complexes large subunit family.

244447:LOC103392445
gene id: 244447:LOC103392445
uniprot id: A0A3P8WLI3
names: Subcellular Location Annotation
messages: Membrane

244447:cd34
gene id: 244447:cd34
uniprot id: A0A3P8WJH8
names: Subcellular Location Annotation
messages: Membrane

244447:LOC103377203
gene id: 244447:LOC103377203
uniprot id: A0A3P8WNJ5
names: Similarity
messages: Belongs to the GORASP family.

244447:LOC103390777
gene id: 244447:LOC103390777
uniprot id: A0A3P8V142
names: Similarity
messages: Belongs to the tumor necrosis factor family.

244447:LOC103379448
gene id: 244447:LOC103379448
uniprot id: A0A3P8UU58
uniprot id: A0A3P8UVL9
uniprot id: A0A3P8UYN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat L(2)GL family.
messages: Cell membrane
messages: Cytoplasm
messages: Membrane

244447:rhbdd2
gene id: 244447:rhbdd2
uniprot id: A0A3P8VIQ6
names: Subcellular Location Annotation
messages: Membrane

244447:LOC103391046
gene id: 244447:LOC103391046
uniprot id: A0A3P8VZ33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

244447:LOC103395814
gene id: 244447:LOC103395814
uniprot id: A0A3P8VTP6
names: Subcellular Location Annotation
messages: Membrane

244447:LOC103383499
gene id: 244447:LOC103383499
uniprot id: A0A3P8WH96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAGUK family.
messages: Cell membrane

244447:tmem35a
gene id: 244447:tmem35a
uniprot id: A0A3P8UND1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Peroxisome membrane
messages: Vesicle

244447:ndufb10
gene id: 244447:ndufb10
uniprot id: A0A3P8WAQ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit that is involved in the functional assembly of the mitochondrial respiratory chain complex I. Complex I has an NADH dehydrogenase activity with ubiquinone as an immediate electron acceptor and mediates the transfer of electrons from NADH to the respiratory chain.
messages: Belongs to the complex I NDUFB10 subunit family.
messages: Mitochondrion inner membrane

244447:LOC103395697
gene id: 244447:LOC103395697
uniprot id: A0A3P8VAM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ripply family.
messages: Nucleus

244447:LOC103377652
gene id: 244447:LOC103377652
uniprot id: A0A3P8UV66
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. RAC subfamily.

244447:dmrt3
gene id: 244447:dmrt3
uniprot id: A0A3P8WZT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DMRT family.
messages: Nucleus

244447:gga3
gene id: 244447:gga3
uniprot id: A0A3P8W5D9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GGA protein family.
messages: Early endosome membrane
messages: Endosome membrane
messages: trans-Golgi network membrane

244447:tmc7
gene id: 244447:tmc7
uniprot id: A0A3P8VPA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMC family.
messages: Membrane

244447:LOC103399920
gene id: 244447:LOC103399920
uniprot id: A0A3P8UU57
names: Similarity
messages: Belongs to the SPIN/STSY family.

244447:hacd4
gene id: 244447:hacd4
uniprot id: A0A3P8WQK9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the very long-chain fatty acids dehydratase HACD family.
messages: Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

244447:LOC103393126
gene id: 244447:LOC103393126
uniprot id: A0A3P8WHM4
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. METL family.
messages: S-adenosyl-L-methionine-dependent methyltransferase.

244447:dusp1
gene id: 244447:dusp1
uniprot id: A0A3P8W3U2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
messages: Nucleus

244447:LOC103381142
gene id: 244447:LOC103381142
uniprot id: A0A3P8USL8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

244447:LOC103394577
gene id: 244447:LOC103394577
uniprot id: A0A3P8VAG6
uniprot id: A0A3P8VD33
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Nucleus

244447:c5h19orf12
gene id: 244447:c5h19orf12
uniprot id: A0A3P8UF49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the C19orf12 family.
messages: Mitochondrion membrane

244447:tent5b
gene id: 244447:tent5b
uniprot id: A0A3P8UYQ5
names: Similarity
messages: Belongs to the TENT family.

244447:LOC103393848
gene id: 244447:LOC103393848
uniprot id: A0A3P8WTF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CART family.
messages: Secreted

244447:dpp7
gene id: 244447:dpp7
uniprot id: A0A3P8VE53
uniprot id: A0A3P8VGW9
names: Similarity
messages: Belongs to the peptidase S28 family.

244447:LOC103389758
gene id: 244447:LOC103389758
uniprot id: A0A3P8W257
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the hemopexin family.
messages: Binds heme and transports it to the liver for breakdown and iron recovery, after which the free hemopexin returns to the circulation.
messages: Secreted

244447:LOC103388396
gene id: 244447:LOC103388396
uniprot id: A0A3P8V4I6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STEAP family.
messages: Endosome membrane
messages: Membrane

244447:LOC103390917
gene id: 244447:LOC103390917
uniprot id: A0A3P8VAI0
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

244447:LOC103391129
gene id: 244447:LOC103391129
uniprot id: A0A3P8W454
names: Subcellular Location Annotation
messages: Lysosome membrane
messages: Membrane

244447:LOC103386340
gene id: 244447:LOC103386340
uniprot id: A0A3P8VL26
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

244447:mrpl58
gene id: 244447:mrpl58
uniprot id: A0A3P8WV87
names: Subcellular Location Annotation
messages: Mitochondrion

244447:tekt2
gene id: 244447:tekt2
uniprot id: A0A3P8VLG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tektin family.
messages: flagellum

244447:LOC103383644
gene id: 244447:LOC103383644
uniprot id: A0A3P8WIB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM151 family.
messages: Membrane

244447:LOC103392749
gene id: 244447:LOC103392749
uniprot id: A0A3P8VNC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HEXIM family.
messages: Nucleus

244447:cep55
gene id: 244447:cep55
uniprot id: A0A3P8V6S8
names: Subcellular Location Annotation
messages: Cytoplasm

244447:rcan3
gene id: 244447:rcan3
uniprot id: A0A3P8URJ9
uniprot id: A0A3P8URK2
names: Similarity
messages: Belongs to the RCAN family.

244447:ism1
gene id: 244447:ism1
uniprot id: A0A3P8VBS7
names: Similarity
messages: Belongs to the isthmin family.

244447:LOC103381738
gene id: 244447:LOC103381738
uniprot id: A0A3P8VZ00
uniprot id: A0A3P8VZ09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

244447:bicd1
gene id: 244447:bicd1
uniprot id: A0A3P8UXK8
names: Similarity
messages: Belongs to the BicD family.

244447:pgls
gene id: 244447:pgls
uniprot id: A0A3P8W1K5
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

244447:LOC103394100
gene id: 244447:LOC103394100
uniprot id: A0A3P8VSQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/IRO homeobox family.
messages: Nucleus

244447:LOC103391627
gene id: 244447:LOC103391627
uniprot id: A0A3P8UV68
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

244447:rmnd1
gene id: 244447:rmnd1
uniprot id: A0A3P8V889
names: Similarity
messages: Belongs to the RMD1/sif2 family.

244447:nup58
gene id: 244447:nup58
uniprot id: A0A3P8VD27
uniprot id: A0A3P8VFY4
uniprot id: A0A3P8VL72
names: Subcellular Location Annotation
messages: nuclear pore complex

244447:hsf2
gene id: 244447:hsf2
uniprot id: A0A3P8WET9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSF family.
messages: Nucleus

244447:LOC103384016
gene id: 244447:LOC103384016
uniprot id: A0A3P8UIP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDC50/LEM3 family.
messages: Cell membrane
messages: Golgi apparatus
messages: Membrane
messages: secretory vesicle membrane

244447:ube2g1
gene id: 244447:ube2g1
uniprot id: A0A3P8VR08
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

244447:maea
gene id: 244447:maea
uniprot id: A0A3P8UWW5
names: Subcellular Location Annotation
messages: Nucleus matrix

244447:LOC103393280
gene id: 244447:LOC103393280
uniprot id: A0A3P8WMA1
names: Similarity
messages: Belongs to the DeSI family.

244447:ebpl
gene id: 244447:ebpl
uniprot id: A0A3P8VG38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EBP family.
messages: Endoplasmic reticulum membrane
messages: Membrane

244447:tmbim4
gene id: 244447:tmbim4
uniprot id: A0A3P8WLY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

244447:grwd1
gene id: 244447:grwd1
uniprot id: A0A3P8WSJ0
names: Subcellular Location Annotation
messages: Nucleus

244447:LOC103397580
gene id: 244447:LOC103397580
uniprot id: A0A3P8WJE4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ODF2 family.
messages: centrosome

244447:cdk7
gene id: 244447:cdk7
uniprot id: A0A3P8WM76
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.

244447:piwil2
gene id: 244447:piwil2
uniprot id: A0A059VQN1
uniprot id: A0A3P8VWD3
names: Similarity
messages: Belongs to the argonaute family.

244447:sec22b
gene id: 244447:sec22b
uniprot id: A0A3P8V8E4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Melanosome
messages: Membrane
messages: SNARE involved in targeting and fusion of ER-derived transport vesicles with the Golgi complex as well as Golgi-derived retrograde transport vesicles with the ER.
messages: cis-Golgi network membrane
messages: trans-Golgi network membrane

244447:LOC103384957
gene id: 244447:LOC103384957
uniprot id: A0A3P8V7H2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the somatostatin family.
messages: Secreted
messages: Somatostatin inhibits the release of somatotropin.

244447:mvk
gene id: 244447:mvk
uniprot id: A0A3P8WTG7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Mevalonate kinase subfamily.
messages: Catalyzes the phosphorylation of mevalonate to mevalonate 5-phosphate, a key step in isoprenoid and cholesterol biosynthesis.
messages: Cytoplasm

244447:nt5e
gene id: 244447:nt5e
uniprot id: A0A3P8V165
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 5'-nucleotidase family.
messages: Membrane

244447:LOC103379927
gene id: 244447:LOC103379927
uniprot id: A0A3P8UL90
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

244447:tcea1
gene id: 244447:tcea1
uniprot id: A0A3P8W549
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFS-II family.
messages: Necessary for efficient RNA polymerase II transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by S-II allows the resumption of elongation from the new 3'-terminus.
messages: Nucleus

244447:LOC103388767
gene id: 244447:LOC103388767
uniprot id: A0A3P8VY16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GRB7/10/14 family.
messages: Cytoplasm

244447:galnt15
gene id: 244447:galnt15
uniprot id: A0A3P8VZT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

244447:mtmr6
gene id: 244447:mtmr6
uniprot id: A0A3P8VFJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.
messages: Cytoplasm

244447:hdhd3
gene id: 244447:hdhd3
uniprot id: A0A3P8UJG3
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

244447:gucy1a1
gene id: 244447:gucy1a1
uniprot id: A0A3P8UYI9
names: Similarity
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.

244447:mrps12
gene id: 244447:mrps12
uniprot id: A0A3P8UN93
names: Similarity
messages: Belongs to the universal ribosomal protein uS12 family.

244447:acadsb
gene id: 244447:acadsb
uniprot id: A0A3P8WPI9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

244447:LOC103395866
gene id: 244447:LOC103395866
uniprot id: A0A3P8VVK5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELL/occludin family.
messages: Cell membrane
messages: May play a role in the formation and regulation of the tight junction (TJ) paracellular permeability barrier.
messages: Membrane
messages: tight junction

244447:LOC103380740
gene id: 244447:LOC103380740
uniprot id: A0A3P8WTW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine beta (chemokine CC) family.
messages: Secreted

244447:bora
gene id: 244447:bora
uniprot id: A0A3P8UQK6
names: Similarity
messages: Belongs to the BORA family.

244447:LOC103389212
gene id: 244447:LOC103389212
uniprot id: A0A3P8UL00
names: Similarity
messages: Belongs to the glycosyl hydrolase 47 family.

244447:LOC103379080
gene id: 244447:LOC103379080
uniprot id: A0A3P8VWR7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cyclin family. Cyclin AB subfamily.
messages: Belongs to the cyclin family. Cyclin D subfamily.
messages: Cytoplasm
messages: Essential for the control of the cell cycle at the G2/M (mitosis) transition.
messages: Interacts with the CDK1 protein kinase to form a serine/threonine kinase holoenzyme complex also known as maturation promoting factor (MPF). The cyclin subunit imparts substrate specificity to the complex.
messages: Nucleus

244447:ndp
gene id: 244447:ndp
uniprot id: A0A3P8UGB9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DAN family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

244447:LOC103383970
gene id: 244447:LOC103383970
uniprot id: A0A3P8VJX7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

244447:LOC103385432
gene id: 244447:LOC103385432
uniprot id: A0A3P8WXN4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IRF family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

244447:lpcat4
gene id: 244447:lpcat4
uniprot id: A0A3P8WM49
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

244447:LOC103398039
gene id: 244447:LOC103398039
uniprot id: A0A3P8VWA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the patched family.
messages: Membrane

244447:ssr4
gene id: 244447:ssr4
uniprot id: A0A3P8UP77
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP-delta family.
messages: Heterotetramer of TRAP-alpha, TRAP-beta, TRAP-delta and TRAP-gamma.
messages: Membrane
messages: TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins.

244447:sdf4
gene id: 244447:sdf4
uniprot id: A0A3P8WPB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CREC family.
messages: Golgi apparatus lumen

244447:LOC103392588
gene id: 244447:LOC103392588
uniprot id: A0A3P8X4V7
names: Similarity
messages: Belongs to the globin family.

244447:LOC103393946
gene id: 244447:LOC103393946
uniprot id: A0A3P8VTM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XK family.
messages: Membrane

244447:slc35e4
gene id: 244447:slc35e4
uniprot id: A0A3P8UHB8
names: Subcellular Location Annotation
messages: Membrane

244447:snrnp27
gene id: 244447:snrnp27
uniprot id: A0A3P8VLY7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SNUT3 family.
messages: May play a role in mRNA splicing.
messages: Nucleus
messages: Part of a tri-snRNP complex.

244447:LOC103390125
gene id: 244447:LOC103390125
uniprot id: A0A3P8WJ16
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

244447:LOC103393194
gene id: 244447:LOC103393194
uniprot id: A0A3P8WRF3
uniprot id: A0A3P8WTT4
names: Similarity
messages: Belongs to the ribose-phosphate pyrophosphokinase family.

244447:LOC103378804
gene id: 244447:LOC103378804
uniprot id: A0A3P8UWQ2
names: Subcellular Location Annotation
messages: Membrane

244447:LOC103396474
gene id: 244447:LOC103396474
uniprot id: A0A3P8WG54
uniprot id: A0A3P8WIT9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tropomyosin family.
messages: cytoskeleton

244447:slc12a9
gene id: 244447:slc12a9
uniprot id: A0A3P8WLY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC12A transporter family.
messages: Cell membrane
messages: Membrane

244447:pmvk
gene id: 244447:pmvk
uniprot id: A0A3P8WYU0
names: Subcellular Location Annotation
messages: cytosol

244447:fam126a
gene id: 244447:fam126a
uniprot id: A0A3P8VE95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM126 family.
messages: Cell membrane
messages: Membrane
messages: cytosol

244447:LOC103381544
gene id: 244447:LOC103381544
uniprot id: A0A3P8VJZ3
uniprot id: A0A3P8VKK8
uniprot id: A0A3P8VMW5
uniprot id: A0A3P8VQV4
uniprot id: A0A3P8VT37
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

244447:LOC103382594
gene id: 244447:LOC103382594
uniprot id: A0A3P8VA06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CREC family.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus
messages: Melanosome
messages: Membrane
messages: Sarcoplasmic reticulum lumen
messages: Secreted

244447:gcm2
gene id: 244447:gcm2
uniprot id: A0A3P8WUE1
names: Subcellular Location Annotation
messages: Nucleus

244447:LOC103377367
gene id: 244447:LOC103377367
uniprot id: A0A3P8WSA2
names: Similarity
messages: Belongs to the ADP-ribosyl cyclase family.

244447:LOC103379992
gene id: 244447:LOC103379992
uniprot id: A0A3P8UVH8
names: Subcellular Location Annotation
messages: Membrane

244447:tmem8b
gene id: 244447:tmem8b
uniprot id: A0A3P8VAZ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM8 family.
messages: Cell membrane
messages: Membrane

244447:LOC103384147
gene id: 244447:LOC103384147
uniprot id: A0A3P8W5K0
names: Subcellular Location Annotation
messages: Membrane

244447:LOC103389090
gene id: 244447:LOC103389090
uniprot id: A0A3P8WLC7
names: Similarity
messages: Belongs to the protein kinase superfamily.

244447:pclaf
gene id: 244447:pclaf
uniprot id: A0A3P8X7D5
names: Subcellular Location Annotation
messages: Nucleus
messages: perinuclear region

244447:ghrh
gene id: 244447:ghrh
uniprot id: E0ADE7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glucagon family.
messages: Secreted

244447:hsbp1
gene id: 244447:hsbp1
uniprot id: A0A3P8X6S7
names: Similarity
messages: Belongs to the HSBP1 family.

244447:LOC103394611
gene id: 244447:LOC103394611
uniprot id: A0A3P8VGC3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes.
messages: Belongs to the dynein light intermediate chain family.
messages: Homodimer. The cytoplasmic dynein 1 complex consists of two catalytic heavy chains (HCs) and a number of non-catalytic subunits presented by intermediate chains (ICs).
messages: cytoskeleton

244447:arhgef9
gene id: 244447:arhgef9
uniprot id: A0A3P8WRG3
uniprot id: A0A3P8WTZ0
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Acts as guanine nucleotide exchange factor (GEF) for CDC42. Promotes formation of GPHN clusters.
messages: Cytoplasm
messages: Interacts with GPHN.
messages: Postsynaptic density

244447:LOC103388333
gene id: 244447:LOC103388333
uniprot id: A0A3P8UZI8
uniprot id: A0A3P8V140
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

244447:cdk8
gene id: 244447:cdk8
uniprot id: A0A3P8WMP4
names: Similarity
messages: Belongs to the protein kinase superfamily.

244447:tmem182
gene id: 244447:tmem182
uniprot id: A0A3P8UY22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM182 family.
messages: Cell membrane
messages: Membrane

244447:papss1
gene id: 244447:papss1
uniprot id: A0A3P8UTN2
names: Similarity
messages: In the C-terminal section; belongs to the sulfate adenylyltransferase family.
messages: In the N-terminal section; belongs to the APS kinase family.

244447:LOC103387068
gene id: 244447:LOC103387068
uniprot id: A0A3P8UL10
names: Caution
names: Similarity
messages: Belongs to the peptidase M14 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

244447:impact
gene id: 244447:impact
uniprot id: A0A3P8UUB8
uniprot id: A0A3P8UVY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IMPACT family.
messages: Cytoplasm

244447:LOC103390348
gene id: 244447:LOC103390348
uniprot id: A0A3P8VJ23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the borealin family.
messages: centromere

244447:LOC103388498
gene id: 244447:LOC103388498
uniprot id: A0A3P8V8Q8
names: Caution
names: Similarity
messages: Belongs to the FXYD family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

244447:ints2
gene id: 244447:ints2
uniprot id: A0A3P8VSY7
names: Similarity
messages: Belongs to the Integrator subunit 2 family.

244447:uts2r
gene id: 244447:uts2r
uniprot id: A0A3P8UIR5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: High affinity receptor for urotensin-2 and urotensin-2B. The activity of this receptor is mediated by a G-protein that activate a phosphatidylinositol-calcium second messenger system.
messages: Membrane

244447:LOC103389315
gene id: 244447:LOC103389315
uniprot id: A0A3P8UPS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

244447:LOC103395088
gene id: 244447:LOC103395088
uniprot id: A0A3P8VIP9
names: Similarity
messages: Belongs to the PTEN phosphatase protein family.

244447:LOC103395854
gene id: 244447:LOC103395854
uniprot id: A0A3P8VWY0
names: Similarity
messages: Belongs to the UQCRH/QCR6 family.

244447:LOC103378915
gene id: 244447:LOC103378915
uniprot id: A0A3P8VBP3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Heterooligomer of subunits alpha (IDH3A), beta (IDH3B), and gamma (IDH3G) in the apparent ratio of 2:1:1. The heterodimer containing one IDH3A and one IDH3B subunit and the heterodimer containing one IDH3A and one IDH3G subunit assemble into a heterotetramer (which contains two subunits of IDH3A, one of IDH3B and one of IDH3G) and further into the heterooctamer.
messages: Mitochondrion

244447:LOC103383579
gene id: 244447:LOC103383579
uniprot id: A0A3P8UUQ3
names: Similarity
messages: Belongs to the ribose-phosphate pyrophosphokinase family.

244447:rpl38
gene id: 244447:rpl38
uniprot id: A0A3P8W7E2
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL38 family.

244447:LOC103397609
gene id: 244447:LOC103397609
uniprot id: A0A3P8WS54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

244447:LOC103394193
gene id: 244447:LOC103394193
uniprot id: A0A3P8W1F4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM54 family.
messages: Membrane

244447:pyroxd1
gene id: 244447:pyroxd1
uniprot id: A0A3P8W5X4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. PYROXD1 subfamily.
messages: sarcomere

244447:dmgdh
gene id: 244447:dmgdh
uniprot id: A0A3P8W5D5
names: Similarity
messages: Belongs to the GcvT family.

244447:cisd2
gene id: 244447:cisd2
uniprot id: A0A3P8VQC8
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Homodimer.
messages: Mitochondrion outer membrane
messages: Regulator of autophagy that contributes to antagonize becn1-mediated cellular autophagy at the endoplasmic reticulum. Participates in the interaction of bcl2 with becn1 and is required for bcl2-mediated depression of endoplasmic reticulum Ca(2+) stores during autophagy.

244447:anks1a
gene id: 244447:anks1a
uniprot id: A0A3P8WLY5
names: Subcellular Location Annotation
messages: Cytoplasm

244447:LOC103394509
gene id: 244447:LOC103394509
uniprot id: A0A3P8V4A1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCN family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

244447:pick1
gene id: 244447:pick1
uniprot id: A0A3P8V7U5
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Probable adapter protein that bind to and organize the subcellular localization of a variety of membrane proteins containing some PDZ recognition sequence. Involved in the clustering of various receptors, possibly by acting at the receptor internalization level. Plays a role in synaptic plasticity by regulating the trafficking and internalization of AMPA receptors. May be regulated upon PRKCA activation. May regulate ASIC1/ASIC3 channel. Regulates actin polymerization by inhibiting the actin-nucleating activity of the Arp2/3 complex; the function is competitive with nucleation promoting factors and is linked to neuronal morphology regulation and AMPA receptor (AMPAR) endocytosis. Via interaction with the Arp2/3 complex involved in regulation of synaptic plasicity of excitatory synapses and required for spine shrinkage during long-term depression (LTD). Involved in regulation of astrocyte morphology, antagonistic to Arp2/3 complex activator WASL/N-WASP function.
messages: cytoskeleton
messages: perinuclear region
messages: synaptosome

244447:LOC103388447
gene id: 244447:LOC103388447
uniprot id: A0A3P8V699
names: Similarity
messages: Belongs to the NDRG family.

244447:cdc20b
gene id: 244447:cdc20b
uniprot id: A0A3P8VCI8
names: Similarity
messages: Belongs to the WD repeat CDC20/Fizzy family.

244447:derl2
gene id: 244447:derl2
uniprot id: A0A3P8VK27
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the derlin family.
messages: Endoplasmic reticulum membrane
messages: Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

244447:qpctl
gene id: 244447:qpctl
uniprot id: A0A3P8WMK1
names: Similarity
messages: Belongs to the glutaminyl-peptide cyclotransferase family.

244447:LOC103389605
gene id: 244447:LOC103389605
uniprot id: A0A3P8V4H0
names: Similarity
messages: Belongs to the cytochrome P450 family.

244447:mybbp1a
gene id: 244447:mybbp1a
uniprot id: A0A3P8WWR0
names: Similarity
messages: Belongs to the MYBBP1A family.

244447:cacng4
gene id: 244447:cacng4
uniprot id: A0A3P8W3A8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
messages: Membrane
messages: Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs), including GRIA1 and GRIA4. Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization.

244447:LOC103381494
gene id: 244447:LOC103381494
uniprot id: A0A3P8VD02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.
messages: Membrane

244447:acer2
gene id: 244447:acer2
uniprot id: A0A3P8V2A0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alkaline ceramidase family.
messages: Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

244447:elovl7
gene id: 244447:elovl7
uniprot id: A0A3P8WL58
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELO family. ELOVL7 subfamily.
messages: Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme with higher activity toward C18 acyl-CoAs, especially C18:3(n-3) acyl-CoAs and C18:3(n-6)-CoAs. Also active toward C20:4-, C18:0-, C18:1-, C18:2- and C16:0-CoAs, and weakly toward C20:0-CoA. Little or no activity toward C22:0-, C24:0-, or C26:0-CoAs. May participate to the production of saturated and polyunsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

244447:inpp4b
gene id: 244447:inpp4b
uniprot id: A0A3P8X2C6
names: Similarity
messages: Belongs to the inositol 3,4-bisphosphate 4-phosphatase family.

244447:LOC103387203
gene id: 244447:LOC103387203
uniprot id: A0A3P8V1S3
names: Caution
names: Similarity
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

244447:ccnk
gene id: 244447:ccnk
uniprot id: A0A3P8WRN5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cyclin family. Cyclin AB subfamily.
messages: Essential for the control of the cell cycle at the G2/M (mitosis) transition.
messages: Interacts with the CDK1 protein kinase to form a serine/threonine kinase holoenzyme complex also known as maturation promoting factor (MPF). The cyclin subunit imparts substrate specificity to the complex.

244447:vsig10
gene id: 244447:vsig10
uniprot id: A0A3P8X1I9
names: Subcellular Location Annotation
messages: Membrane

244447:rtn4
gene id: 244447:rtn4
uniprot id: A0A3P8UJ21
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

244447:LOC103396224
gene id: 244447:LOC103396224
uniprot id: A0A3P8VFQ4
names: Similarity
messages: Belongs to the GORASP family.

244447:med11
gene id: 244447:med11
uniprot id: A0A3P8VBZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 11 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

244447:pnrc2
gene id: 244447:pnrc2
uniprot id: A0A3P8WXY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PNRC family. PNRC2 subfamily.
messages: Nucleus
messages: P-body

244447:ydjc
gene id: 244447:ydjc
uniprot id: A0A3P8VNN8
names: Function
names: Similarity
messages: Belongs to the YdjC deacetylase family.
messages: Probably catalyzes the deacetylation of acetylated carbohydrates an important step in the degradation of oligosaccharides.

244447:LOC103377254
gene id: 244447:LOC103377254
uniprot id: A0A3P8WJU0
names: Function
names: Similarity
messages: Belongs to the OHCU decarboxylase family.
messages: Catalyzes the stereoselective decarboxylation of 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU) to (S)-allantoin.

244447:LOC103380388
gene id: 244447:LOC103380388
uniprot id: A0A3P8VAB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.
messages: Nucleus

244447:bckdha
gene id: 244447:bckdha
uniprot id: A0A3P8V740
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BCKDHA family.
messages: Heterotetramer of alpha and beta chains.
messages: The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).

244447:dld
gene id: 244447:dld
uniprot id: A0A3P8UQB0
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.
messages: acrosome
messages: flagellum

244447:LOC103386085
gene id: 244447:LOC103386085
uniprot id: A0A3P8UYX4
names: Similarity
messages: Belongs to the MDFI family.

244447:LOC103393631
gene id: 244447:LOC103393631
uniprot id: A0A3P8WHD8
names: Similarity
messages: Belongs to the ribose-phosphate pyrophosphokinase family.

244447:LOC103381414
gene id: 244447:LOC103381414
uniprot id: A0A3P8V552
names: Similarity
messages: Belongs to the SMARCD family.

244447:cpvl
gene id: 244447:cpvl
uniprot id: A0A3P8V0B1
names: Similarity
messages: Belongs to the peptidase S10 family.

244447:pabpc4
gene id: 244447:pabpc4
uniprot id: A0A3P8UCI7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyadenylate-binding protein type-1 family.
messages: Binds the poly(A) tail of mRNA.
messages: Cytoplasm

244447:LOC103383380
gene id: 244447:LOC103383380
uniprot id: A0A3P8ULT6
names: Subcellular Location Annotation
messages: Lysosome membrane
messages: Membrane

244447:p3h2
gene id: 244447:p3h2
uniprot id: A0A3P8WAD2
names: Similarity
messages: Belongs to the leprecan family.

244447:czh9orf64
gene id: 244447:czh9orf64
uniprot id: A0A3P8W1I1
names: Function
names: Similarity
messages: Belongs to the queuosine salvage protein family.
messages: Involved in salvaging queuosine.

244447:mcmbp
gene id: 244447:mcmbp
uniprot id: A0A3P8VWI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCMBP family.
messages: Nucleus

244447:elavl4
gene id: 244447:elavl4
uniprot id: A0A3P8WVH3
uniprot id: A0A3P8WXH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM elav family.
messages: Cytoplasm
messages: Perikaryon
messages: axon
messages: dendrite
messages: growth cone

244447:arrdc1
gene id: 244447:arrdc1
uniprot id: A0A3P8WYI2
names: Similarity
messages: Belongs to the arrestin family.

244447:LOC103393476
gene id: 244447:LOC103393476
uniprot id: A0A3P8VI94
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TTC30/dfy-1/fleer family.
messages: Required for polyglutamylation of axonemal tubulin. Plays a role in anterograde intraflagellar transport (IFT), the process by which cilia precursors are transported from the base of the cilium to the site of their incorporation at the tip.
messages: cilium

244447:LOC103381857
gene id: 244447:LOC103381857
uniprot id: A0A3P8WDM7
names: Subcellular Location Annotation
messages: Nucleus

244447:tmem134
gene id: 244447:tmem134
uniprot id: A0A3P8VEF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM134/TMEM230 family.
messages: Membrane

244447:LOC103386631
gene id: 244447:LOC103386631
uniprot id: A0A3P8WJU4
names: Subcellular Location Annotation
messages: Membrane

244447:LOC103390011
gene id: 244447:LOC103390011
uniprot id: A0A3P8W2P2
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

244447:LOC103392832
gene id: 244447:LOC103392832
uniprot id: A0A3P8VZB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neuropeptide B/W family.
messages: Secreted

244447:acer1
gene id: 244447:acer1
uniprot id: A0A3P8WLP2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alkaline ceramidase family.
messages: Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid.
messages: Membrane

244447:LOC103384934
gene id: 244447:LOC103384934
uniprot id: A0A3P8V4L8
names: Subcellular Location Annotation
messages: Nucleus

244447:LOC103389399
gene id: 244447:LOC103389399
uniprot id: A0A3P8UXN5
names: Subcellular Location Annotation
messages: Synapse
messages: axon
messages: dendritic spine

244447:LOC103378812
gene id: 244447:LOC103378812
uniprot id: A0A3P8UNW7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

244447:cdx4
gene id: 244447:cdx4
uniprot id: A0A3P8V553
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Caudal homeobox family.
messages: Nucleus

244447:LOC103383515
gene id: 244447:LOC103383515
uniprot id: A0A3P8WC03
uniprot id: A0A3P8WJX3
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes two steps in the biosynthesis of the molybdenum cofactor. In the first step, molybdopterin is adenylated. Subsequently, molybdate is inserted into adenylated molybdopterin and AMP is released.
messages: In the C-terminal section; belongs to the MoeA family.
messages: In the N-terminal section; belongs to the MoaB/Mog family.

244447:LOC103390460
gene id: 244447:LOC103390460
uniprot id: A0A3P8UND4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM120 family.
messages: Membrane
messages: Nucleus inner membrane

244447:osbpl6
gene id: 244447:osbpl6
uniprot id: A0A3P8URQ9
names: Similarity
messages: Belongs to the OSBP family.

244447:e2f3
gene id: 244447:e2f3
uniprot id: A0A3P8UUV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the E2F/DP family.
messages: Nucleus

244447:LOC103393022
gene id: 244447:LOC103393022
uniprot id: A0A3P8W9U9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

244447:LOC103386843
gene id: 244447:LOC103386843
uniprot id: A0A3P8UNR8
names: Similarity
messages: Belongs to the peptidase C2 family.

244447:cul3
gene id: 244447:cul3
uniprot id: A0A3P8WYM9
names: Similarity
messages: Belongs to the cullin family.

244447:cenpt
gene id: 244447:cenpt
uniprot id: A0A3P8V2N3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CENP-T/CNN1 family.
messages: Nucleus
messages: kinetochore

244447:LOC103382158
gene id: 244447:LOC103382158
uniprot id: A0A3P8UIK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CYBC1 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

244447:LOC103380112
gene id: 244447:LOC103380112
uniprot id: A0A3P8V7M2
names: Similarity
messages: Belongs to the PP2C family.

244447:LOC103397281
gene id: 244447:LOC103397281
uniprot id: A0A3P8X0M4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

244447:apaf1
gene id: 244447:apaf1
uniprot id: A0A3P8VCJ3
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Monomer. Oligomerizes upon binding of cytochrome c and dATP.
messages: Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.

244447:LOC103390091
gene id: 244447:LOC103390091
uniprot id: A0A3P8WBP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

244447:LOC103380541
gene id: 244447:LOC103380541
uniprot id: A0A3P8WC51
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

244447:LOC103383538
gene id: 244447:LOC103383538
uniprot id: A0A3P8UW34
names: Similarity
messages: Belongs to the PDCD4 family.

244447:LOC103377253
gene id: 244447:LOC103377253
uniprot id: A0A3P8WH61
names: Function
names: Similarity
messages: Belongs to the OHCU decarboxylase family.
messages: Catalyzes the stereoselective decarboxylation of 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU) to (S)-allantoin.

244447:LOC103379383
gene id: 244447:LOC103379383
uniprot id: A0A3P8W3L5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

244447:LOC103387079
gene id: 244447:LOC103387079
uniprot id: A0A3P8UT13
names: Similarity
messages: Belongs to the flagellar radial spoke RSP3 family.

244447:LOC103384618
gene id: 244447:LOC103384618
uniprot id: A0A3P8UQH9
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP, AMP, or fructose 2,6-bisphosphate, and allosterically inhibited by ATP or citrate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade "E" sub-subfamily.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homo- and heterotetramers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

244447:LOC103394269
gene id: 244447:LOC103394269
uniprot id: A0A3P8WH02
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyadenylate-binding protein type-1 family.
messages: Binds the poly(A) tail of mRNA.
messages: Cytoplasm

244447:clpp
gene id: 244447:clpp
uniprot id: A0A3P8W4R8
names: Similarity
messages: Belongs to the peptidase S14 family.

244447:mall
gene id: 244447:mall
uniprot id: A0A3P8UBS1
names: Subcellular Location Annotation
messages: Membrane

244447:LOC103390727
gene id: 244447:LOC103390727
uniprot id: A0A3P8UY50
names: Subcellular Location Annotation
messages: Membrane

244447:tmem107
gene id: 244447:tmem107
uniprot id: A0A3P8ULR3
uniprot id: A0A3P8ULS0
names: Subcellular Location Annotation
messages: Membrane

244447:ndufs5
gene id: 244447:ndufs5
uniprot id: A0A3P8VFK2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFS5 subunit family.
messages: Mammalian complex I is composed of 45 different subunits. This is a component of the iron-sulfur (IP) fragment of the enzyme.
messages: Membrane
messages: Mitochondrion inner membrane

244447:LOC103390873
gene id: 244447:LOC103390873
uniprot id: A0A3P8V5H4
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain.

244447:LOC103386932
gene id: 244447:LOC103386932
uniprot id: A0A3P8UNI3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UDPGP type 1 family.
messages: Homooctamer.
messages: UTP--glucose-1-phosphate uridylyltransferase catalyzing the conversion of glucose-1-phosphate into UDP-glucose, a crucial precursor for the production of glycogen.

244447:LOC103397968
gene id: 244447:LOC103397968
uniprot id: A0A3P8VLK3
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

244447:spi1
gene id: 244447:spi1
uniprot id: A0A3P8UIY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

244447:LOC103397887
gene id: 244447:LOC103397887
uniprot id: A0A3P8V917
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dwarfin/SMAD family.
messages: Cytoplasm
messages: Nucleus

244447:LOC103379784
gene id: 244447:LOC103379784
uniprot id: A0A3P8UIC4
names: Subcellular Location Annotation
messages: Nucleus

244447:ccnf
gene id: 244447:ccnf
uniprot id: A0A3P8WK88
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cyclin family. Cyclin AB subfamily.
messages: Essential for the control of the cell cycle at the G2/M (mitosis) transition.
messages: Interacts with the CDK1 protein kinase to form a serine/threonine kinase holoenzyme complex also known as maturation promoting factor (MPF). The cyclin subunit imparts substrate specificity to the complex.
messages: centriole
messages: perinuclear region

244447:LOC103392892
gene id: 244447:LOC103392892
uniprot id: A0A3P8VZ36
names: Function
names: Similarity
messages: Belongs to the parvalbumin family.
messages: In muscle, parvalbumin is thought to be involved in relaxation after contraction. It binds two calcium ions.

244447:nim1k
gene id: 244447:nim1k
uniprot id: A0A3P8WKX2
names: Similarity
messages: Belongs to the protein kinase superfamily.

244447:LOC103394316
gene id: 244447:LOC103394316
uniprot id: A0A3P8WCH5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 13 family.
messages: Golgi apparatus membrane
messages: Initiates complex N-linked carbohydrate formation. Essential for the conversion of high-mannose to hybrid and complex N-glycans.
messages: Membrane
messages: The cofactor is mostly bound to the substrate.

244447:hsp90b1
gene id: 244447:hsp90b1
uniprot id: A0A3P8VEI6
names: Similarity
messages: Belongs to the heat shock protein 90 family.

244447:slc25a18
gene id: 244447:slc25a18
uniprot id: A0A3P8USG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

244447:mad1l1
gene id: 244447:mad1l1
uniprot id: A0A3P8USH0
names: Similarity
messages: Belongs to the MAD1 family.

244447:rbm15
gene id: 244447:rbm15
uniprot id: A0A3P8V1D1
names: Similarity
messages: Belongs to the RRM Spen family.

244447:ddx6
gene id: 244447:ddx6
uniprot id: A0A3P8V5Q1
names: Similarity
messages: Belongs to the DEAD box helicase family.

244447:tbp
gene id: 244447:tbp
uniprot id: A0A3P8WVD7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TBP family.
messages: Nucleus

244447:dcp2
gene id: 244447:dcp2
uniprot id: A0A3P8WI04
names: Similarity
messages: Belongs to the Nudix hydrolase family. DCP2 subfamily.

244447:med13
gene id: 244447:med13
uniprot id: A0A3P8VV71
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 13 family.
messages: Component of the Mediator complex, a coactivator involved in regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

244447:LOC103387820
gene id: 244447:LOC103387820
uniprot id: A0A3P8WWK2
names: Similarity
messages: Belongs to the protein kinase superfamily.

244447:slc7a11
gene id: 244447:slc7a11
uniprot id: A0A3P8VCK1
names: Subcellular Location Annotation
messages: Membrane

244447:LOC103394237
gene id: 244447:LOC103394237
uniprot id: A0A3P8W7R6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Membrane

244447:dhrs3
gene id: 244447:dhrs3
uniprot id: A0A3P8WKW7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

244447:tfdp1
gene id: 244447:tfdp1
uniprot id: A0A3P8V1U2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the E2F/DP family.
messages: Nucleus

244447:tph1
gene id: 244447:tph1
uniprot id: A0A3P8V3K7
names: Similarity
messages: Belongs to the biopterin-dependent aromatic amino acid hydroxylase family.

244447:LOC103380368
gene id: 244447:LOC103380368
uniprot id: A0A3P8VJW3
names: Similarity
messages: Belongs to the universal ribosomal protein uL23 family.

244447:cluap1
gene id: 244447:cluap1
uniprot id: A0A3P8WVI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CLUAP1 family.
messages: cilium

244447:LOC103385438
gene id: 244447:LOC103385438
uniprot id: A0A3P8WXI6
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.

244447:LOC103384273
gene id: 244447:LOC103384273
uniprot id: A0A3P8W966
names: Similarity
messages: Belongs to the GST superfamily. Theta family.

244447:rspo3
gene id: 244447:rspo3
uniprot id: A0A3P8VIQ3
names: Similarity
messages: Belongs to the R-spondin family.

244447:LOC103382555
gene id: 244447:LOC103382555
uniprot id: A0A3P8UUP2
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

244447:lix1l
gene id: 244447:lix1l
uniprot id: A0A3P8WE56
names: Similarity
messages: Belongs to the LIX1 family.

244447:LOC103389422
gene id: 244447:LOC103389422
uniprot id: A0A3P8V493
names: Similarity
messages: Belongs to the pleiotrophin family.

244447:slu7
gene id: 244447:slu7
uniprot id: A0A3P8WCC0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associated with the spliceosome.
messages: Belongs to the SLU7 family.
messages: Involved in pre-mRNA splicing.
messages: Nucleus

244447:slc35f6
gene id: 244447:slc35f6
uniprot id: A0A3P8WYE8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SLC35F solute transporter family.
messages: Interacts with SLC25A5.
messages: May play a role as a nucleotide-sugar transporter.
messages: Membrane
messages: Mitochondrion

244447:akt1
gene id: 244447:akt1
uniprot id: A0A3P8UA64
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. RAC subfamily.

244447:rps14
gene id: 244447:rps14
uniprot id: A0A3P8WZM4
names: Similarity
messages: Belongs to the universal ribosomal protein uS11 family.

244447:LOC103381993
gene id: 244447:LOC103381993
uniprot id: A0A3P8W1I2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

244447:LOC103389670
gene id: 244447:LOC103389670
uniprot id: A0A3P8VQ33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

244447:rps6
gene id: 244447:rps6
uniprot id: A0A3P8UTS1
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS6 family.

244447:ddx31
gene id: 244447:ddx31
uniprot id: A0A3P8VL99
names: Similarity
messages: Belongs to the DEAD box helicase family.

244447:LOC103397612
gene id: 244447:LOC103397612
uniprot id: A0A3P8WQ09
names: Similarity
messages: Belongs to the CD36 family.

244447:ndufb1
gene id: 244447:ndufb1
uniprot id: A0A3P8UVF4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFB1 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

244447:ndufs4
gene id: 244447:ndufs4
uniprot id: A0A097RN14
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFS4 subunit family.
messages: Mitochondrion inner membrane

244447:LOC103384741
gene id: 244447:LOC103384741
uniprot id: A0A3P8USS3
names: Similarity
messages: Belongs to the transglutaminase superfamily. Transglutaminase family.

244447:pdp1
gene id: 244447:pdp1
uniprot id: A0A3P8UQ14
names: Similarity
messages: Belongs to the PP2C family.

244447:LOC103395214
gene id: 244447:LOC103395214
uniprot id: A0A3P8VZX5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heparin-binding growth factors family.
messages: Cytoplasm
messages: Nucleus
messages: Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integrins and FGFR1 are essential for FGF1 signaling.
messages: Secreted
messages: cell cortex
messages: cytosol

244447:LOC103386113
gene id: 244447:LOC103386113
uniprot id: A0A3P8V096
names: Similarity
messages: Belongs to the intermediate filament family.

244447:LOC103385197
gene id: 244447:LOC103385197
uniprot id: A0A3P8VKB5
names: Subcellular Location Annotation
messages: Membrane

244447:cpo
gene id: 244447:cpo
uniprot id: A0A3P8UYI6
names: Similarity
messages: Belongs to the peptidase M14 family.

244447:nxf1
gene id: 244447:nxf1
uniprot id: A0A3P8V4I5
uniprot id: A0A3P8V9A9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NXF family.
messages: Cytoplasm
messages: nucleoplasm

244447:phgdh
gene id: 244447:phgdh
uniprot id: A0A3P8W0E6
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

244447:LOC103388877
gene id: 244447:LOC103388877
uniprot id: A0A3P8UYB3
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

244447:LOC103388672
gene id: 244447:LOC103388672
uniprot id: A0A3P8VGP5
names: Similarity
messages: Belongs to the TGF-beta family.

244447:LOC103390916
gene id: 244447:LOC103390916
uniprot id: A0A3P8V6P9
uniprot id: A0A3P8VCN1
names: Similarity
messages: Belongs to the beta-catenin family.

244447:LOC103389898
gene id: 244447:LOC103389898
uniprot id: A0A3P8VU01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily.
messages: Membrane
messages: synaptic vesicle membrane

244447:irak4
gene id: 244447:irak4
uniprot id: D7F473
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with MYD88 and IRAK2 to form a ternary complex called the Myddosome.
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. Pelle subfamily.
messages: Cytoplasm
messages: Serine/threonine-protein kinase that plays a critical role in initiating innate immune response against foreign pathogens.

244447:LOC103376967
gene id: 244447:LOC103376967
uniprot id: A0A3P8VTN0
names: Subcellular Location Annotation
messages: Nucleus

244447:ext2
gene id: 244447:ext2
uniprot id: A0A3P8UQE7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 47 family.
messages: Endoplasmic reticulum membrane

244447:hspb7
gene id: 244447:hspb7
uniprot id: A0A3P8UWF0
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

244447:rhpn1
gene id: 244447:rhpn1
uniprot id: A0A3P8UQA7
names: Similarity
messages: Belongs to the RHPN family.

244447:LOC103397067
gene id: 244447:LOC103397067
uniprot id: A0A3P8VT57
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

244447:LOC103380452
gene id: 244447:LOC103380452
uniprot id: A0A3P8VYL6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase subunit 5A family.
messages: Component of the cytochrome c oxidase (complex IV, CIV), a multisubunit enzyme composed of a catalytic core of 3 subunits and several supernumerary subunits. The complex exists as a monomer or a dimer and forms supercomplexes (SCs) in the inner mitochondrial membrane with ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII).
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
messages: Mitochondrion inner membrane

244447:LOC103387647
gene id: 244447:LOC103387647
uniprot id: A0A3P8WIA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COE family.
messages: Nucleus

244447:LOC103379660
gene id: 244447:LOC103379660
uniprot id: A0A3P8X1V8
names: Subcellular Location Annotation
messages: Membrane

244447:LOC103388276
gene id: 244447:LOC103388276
uniprot id: A0A0H3WFW2
names: Similarity
messages: Belongs to the pyruvate kinase family.

244447:LOC103379915
gene id: 244447:LOC103379915
uniprot id: A0A3P8V4T2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PDCD10 family.
messages: Cell membrane
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Membrane

244447:LOC103390221
gene id: 244447:LOC103390221
uniprot id: A0A3P8WMX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SURF4 family.
messages: Membrane

244447:LOC103381868
gene id: 244447:LOC103381868
uniprot id: A0A3P8WF45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PDK/BCKDK protein kinase family.
messages: Mitochondrion matrix

244447:LOC103388096
gene id: 244447:LOC103388096
uniprot id: A0A3P8UET1
uniprot id: A0A3P8UNA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anion exchanger (TC 2.A.31) family.
messages: Membrane

244447:cutc
gene id: 244447:cutc
uniprot id: A0A3P8VBT4
names: Similarity
messages: Belongs to the CutC family.

244447:LOC103387685
gene id: 244447:LOC103387685
uniprot id: A0A3P8WLC0
names: Similarity
messages: In the C-terminal section; belongs to the sulfate adenylyltransferase family.
messages: In the N-terminal section; belongs to the APS kinase family.

244447:sept10
gene id: 244447:sept10
uniprot id: A0A3P8W0A8
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.

244447:LOC103385643
gene id: 244447:LOC103385643
uniprot id: A0A3P8X469
names: Similarity
messages: Belongs to the WD repeat G protein beta family.

244447:LOC103386190
gene id: 244447:LOC103386190
uniprot id: A0A3P8V808
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.
messages: Membrane

244447:LOC103376752
gene id: 244447:LOC103376752
uniprot id: A0A3P8V7N4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCAMP family.
messages: Membrane

244447:brix1
gene id: 244447:brix1
uniprot id: A0A3P8WZX1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BRX1 family.
messages: Required for biogenesis of the 60S ribosomal subunit.
messages: nucleolus

244447:LOC103396076
gene id: 244447:LOC103396076
uniprot id: A0A3P8WG05
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

244447:stom
gene id: 244447:stom
uniprot id: A0A3P8UMK2
names: Similarity
messages: Belongs to the band 7/mec-2 family.

244447:itih6
gene id: 244447:itih6
uniprot id: A0A3P8VM32
uniprot id: A0A3P8VM73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ITIH family.
messages: Secreted

244447:bcar1
gene id: 244447:bcar1
uniprot id: A0A3P8UJI8
uniprot id: A0A3P8UP24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAS family.
messages: focal adhesion

244447:LOC103388735
gene id: 244447:LOC103388735
uniprot id: A0A3P8VQ23
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

244447:LOC103395257
gene id: 244447:LOC103395257
uniprot id: A0A3P8VZX9
names: Subcellular Location Annotation
messages: Membrane

244447:LOC103386159
gene id: 244447:LOC103386159
uniprot id: A0A3P8V314
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ARPC4 family.
messages: Cell projection
messages: Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament.
messages: cytoskeleton

244447:rps28
gene id: 244447:rps28
uniprot id: A0A3P8VY61
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS28 family.

244447:LOC103393872
gene id: 244447:LOC103393872
uniprot id: A0A3P8WYX8
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. GSK-3 subfamily.

244447:LOC103383141
gene id: 244447:LOC103383141
uniprot id: A0A3P8WX95
names: Similarity
messages: Belongs to the FAM83 family.

244447:ncbp2
gene id: 244447:ncbp2
uniprot id: A0A3P8WTU0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RRM NCBP2 family.
messages: Component of the cap-binding complex (CBC), which binds co-transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense-mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U snRNA and intronless mRNAs export from the nucleus. The CBC complex is essential for a pioneer round of mRNA translation, before steady state translation when the CBC complex is replaced by cytoplasmic cap-binding protein eIF4E. The pioneer round of mRNA translation mediated by the CBC complex plays a central role in nonsense-mediated mRNA decay (NMD), NMD only taking place in mRNAs bound to the CBC complex, but not on eIF4E-bound mRNAs. The CBC complex enhances NMD in mRNAs containing at least one exon-junction complex (EJC), promoting the interaction between upf1 and upf2. The CBC complex is also involved in 'failsafe' NMD, which is independent of the EJC complex, while it does not participate in Staufen-mediated mRNA decay (SMD). During cell proliferation, the CBC complex is also involved in microRNAs (miRNAs) biogenesis via its interaction with srrt/ars2, thereby being required for miRNA-mediated RNA interference. The CBC complex also acts as a negative regulator of parn, thereby acting as an inhibitor of mRNA deadenylation. In the CBC complex, ncbp2/cbp20 recognizes and binds capped RNAs (m7GpppG-capped RNA) but requires ncbp1/cbp80 to stabilize the movement of its N-terminal loop and lock the CBC into a high affinity cap-binding state with the cap structure. The conventional cap-binding complex with NCBP2 binds both small nuclear RNA (snRNA) and messenger (mRNA) and is involved in their export from the nucleus.
messages: Component of the nuclear cap-binding complex (CBC), a heterodimer composed of ncbp1/cbp80 and ncbp2/cbp20 that interacts with m7GpppG-capped RNA.
messages: Nucleus

244447:LOC103392955
gene id: 244447:LOC103392955
uniprot id: A0A3P8W1S6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WFIKKN family.
messages: Membrane

244447:LOC103397493
gene id: 244447:LOC103397493
uniprot id: A0A3P8VV79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CUT homeobox family.
messages: Nucleus

244447:LOC103394677
gene id: 244447:LOC103394677
uniprot id: U3PXD2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

244447:LOC103383647
gene id: 244447:LOC103383647
uniprot id: A0A3P8V0L3
uniprot id: A0A3P8V280
names: Similarity
messages: Belongs to the perilipin family.

244447:LOC103384807
gene id: 244447:LOC103384807
uniprot id: A0A3P8V035
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptophysin/synaptobrevin family.
messages: Membrane

244447:zer1
gene id: 244447:zer1
uniprot id: A0A3P8WVG2
names: Similarity
messages: Belongs to the zyg-11 family.

244447:LOC103381353
gene id: 244447:LOC103381353
uniprot id: A0A3P8V4F2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

244447:pth1r
gene id: 244447:pth1r
uniprot id: A0A3P8W469
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family.
messages: Cell membrane
messages: Membrane

244447:LOC103383735
gene id: 244447:LOC103383735
uniprot id: A0A3P8VA92
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

244447:psmc4
gene id: 244447:psmc4
uniprot id: A0A3P8VXZ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family.
messages: Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. PSMC4 belongs to the heterohexameric ring of AAA (ATPases associated with diverse cellular activities) proteins that unfolds ubiquitinated target proteins that are concurrently translocated into a proteolytic chamber and degraded into peptides.
messages: Cytoplasm

244447:selenoi
gene id: 244447:selenoi
uniprot id: A0A3P8WRE1
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

244447:LOC103384377
gene id: 244447:LOC103384377
uniprot id: A0A3P8WK67
names: Subcellular Location Annotation
messages: Nucleus

244447:cdk4
gene id: 244447:cdk4
uniprot id: A0A3P8UTY0
names: Similarity
messages: Belongs to the protein kinase superfamily.

244447:pou3f2
gene id: 244447:pou3f2
uniprot id: A0A3P8W4K5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POU transcription factor family. Class-3 subfamily.
messages: Nucleus

244447:LOC103386947
gene id: 244447:LOC103386947
uniprot id: H9NID3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycoprotein hormones subunit beta family.
messages: Heterodimer of an alpha and a beta chain.
messages: Involved in gametogenesis and steroidogenesis.
messages: Secreted

244447:inpp1
gene id: 244447:inpp1
uniprot id: A0A3P8UW60
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

244447:psmd12
gene id: 244447:psmd12
uniprot id: A0A3P8W0R9
names: Similarity
messages: Belongs to the proteasome subunit p55 family.

244447:sec61g
gene id: 244447:sec61g
uniprot id: A0A3P8VGR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecE/SEC61-gamma family.
messages: Endoplasmic reticulum membrane
messages: Membrane

244447:c7h12orf57
gene id: 244447:c7h12orf57
uniprot id: A0A3P8UWC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0456 family.
messages: Cytoplasm

244447:glra1
gene id: 244447:glra1
uniprot id: A0A3P8W627
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family. Glycine receptor (TC 1.A.9.3) subfamily. GLRA1 sub-subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Perikaryon
messages: Postsynaptic cell membrane
messages: Synapse
messages: Synaptic cell membrane
messages: dendrite

244447:ndufa1
gene id: 244447:ndufa1
uniprot id: A0A3P8UQZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFA1 subunit family.
messages: Mitochondrion inner membrane

244447:plk3
gene id: 244447:plk3
uniprot id: A0A3P8WLZ8
names: Similarity
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDC5/Polo subfamily.

244447:trove2
gene id: 244447:trove2
uniprot id: A0A3P8VMM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ro 60 kDa family.
messages: Cytoplasm

244447:fer
gene id: 244447:fer
uniprot id: A0A3P8WWW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily.
messages: cytoskeleton

244447:LOC103392810
gene id: 244447:LOC103392810
uniprot id: A0A3P8VWV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptogyrin family.
messages: Membrane

244447:LOC103390461
gene id: 244447:LOC103390461
uniprot id: A0A3P8UG35
names: Subcellular Location Annotation
messages: Chromosome
messages: Nucleus speckle

244447:tspan18
gene id: 244447:tspan18
uniprot id: A0A3P8W1H8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

244447:ints13
gene id: 244447:ints13
uniprot id: A0A3P8VMM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the asunder family.
messages: Cytoplasm
messages: Nucleus

244447:chchd4
gene id: 244447:chchd4
uniprot id: A0A3P8UZ80
names: Subcellular Location Annotation
messages: Mitochondrion intermembrane space

244447:sdad1
gene id: 244447:sdad1
uniprot id: A0A3P8WR12
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SDA1 family.
messages: Required for 60S pre-ribosomal subunits export to the cytoplasm.
messages: nucleolus

244447:ddx55
gene id: 244447:ddx55
uniprot id: A0A3P8W068
names: Similarity
messages: Belongs to the DEAD box helicase family.

244447:mov10
gene id: 244447:mov10
uniprot id: A0A3P8VNH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA2/NAM7 helicase family. SDE3 subfamily.
messages: P-body

244447:vti1a
gene id: 244447:vti1a
uniprot id: A0A3P8VD74
uniprot id: A0A3P8VFY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VTI1 family.
messages: Membrane

244447:itgb1
gene id: 244447:itgb1
uniprot id: A0A3P8VTE2
uniprot id: A0A3P8VVU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin beta chain family.
messages: Cell membrane
messages: Melanosome
messages: Membrane
messages: invadopodium membrane
messages: lamellipodium
messages: ruffle membrane

244447:nr4a2
gene id: 244447:nr4a2
uniprot id: A0A3P8VW23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Cytoplasm
messages: Nucleus

244447:pcnp
gene id: 244447:pcnp
uniprot id: A0A3P8UG79
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Interacts with UHRF2/NIRF.
messages: May be involved in cell cycle regulation.
messages: Nucleus

244447:pofut2
gene id: 244447:pofut2
uniprot id: A0A3P8VTW5
names: Similarity
messages: Belongs to the glycosyltransferase 68 family.

244447:LOC103384915
gene id: 244447:LOC103384915
uniprot id: A0A3P8UZ33
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.

244447:LOC103394206
gene id: 244447:LOC103394206
uniprot id: A0A3P8WCK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Membrane

244447:LOC103393488
gene id: 244447:LOC103393488
uniprot id: A0A3P8VV28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-alpha family. G(12) subfamily.
messages: Membrane

244447:dpm1
gene id: 244447:dpm1
uniprot id: A0A3P8UUU5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycosyltransferase 2 family.
messages: Component of the dolichol-phosphate mannose (DPM) synthase complex.
messages: Endoplasmic reticulum
messages: Transfers mannose from GDP-mannose to dolichol monophosphate to form dolichol phosphate mannose (Dol-P-Man) which is the mannosyl donor in pathways leading to N-glycosylation, glycosyl phosphatidylinositol membrane anchoring, and O-mannosylation of proteins; catalytic subunit of the dolichol-phosphate mannose (DPM) synthase complex.

244447:six4
gene id: 244447:six4
uniprot id: A0A3P8UNK9
names: Subcellular Location Annotation
messages: Nucleus

244447:LOC103397744
gene id: 244447:LOC103397744
uniprot id: A0A3P8WWW1
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

244447:LOC103397731
gene id: 244447:LOC103397731
uniprot id: A0A3P8WXF2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane
messages: Sodium-phosphate symporter which plays a fundamental housekeeping role in phosphate transport.

244447:LOC103399891
gene id: 244447:LOC103399891
uniprot id: A0A3P8UT76
names: Subcellular Location Annotation
messages: Membrane

244447:LOC103379886
gene id: 244447:LOC103379886
uniprot id: A0A3P8UPX3
names: Similarity
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the N-terminal section; belongs to the AAA ATPase family.

244447:fads6
gene id: 244447:fads6
uniprot id: A0A3P8USX2
names: Similarity
messages: Belongs to the fatty acid desaturase type 1 family.

244447:cnksr2
gene id: 244447:cnksr2
uniprot id: A0A3P8UEG6
names: Similarity
messages: Belongs to the CNKSR family.

244447:reep5
gene id: 244447:reep5
uniprot id: A0A3P8VPZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DP1 family.
messages: Membrane

244447:LOC103384694
gene id: 244447:LOC103384694
uniprot id: A0A3P8UQL8
uniprot id: A0A3P8UWS0
names: Subcellular Location Annotation
messages: Membrane

244447:pprc1
gene id: 244447:pprc1
uniprot id: A0A3P8VGP0
names: Subcellular Location Annotation
messages: Nucleus

244447:LOC103380240
gene id: 244447:LOC103380240
uniprot id: A0A3P8V8J5
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Component of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.

244447:stac
gene id: 244447:stac
uniprot id: A0A3P8UT69
names: Subcellular Location Annotation
messages: sarcolemma

244447:LOC103387492
gene id: 244447:LOC103387492
uniprot id: A0A3P8VLC8
names: Similarity
messages: Belongs to the cytochrome P450 family.

244447:itga2
gene id: 244447:itga2
uniprot id: A0A3P8X300
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

244447:LOC103396934
gene id: 244447:LOC103396934
uniprot id: A0A3P8VIE4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS37 family.
messages: Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. May be involved in cell growth and differentiation.
messages: Endosome membrane
messages: Late endosome membrane

244447:LOC103377807
gene id: 244447:LOC103377807
uniprot id: A0A3P8V725
names: Similarity
messages: Belongs to the CRK family.

244447:LOC103394521
gene id: 244447:LOC103394521
uniprot id: A0A3P8V7E0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DPM3 family.
messages: Component of the dolichol-phosphate mannose (DPM) synthase complex.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Stabilizer subunit of the dolichol-phosphate mannose (DPM) synthase complex; tethers catalytic subunit to the ER.

244447:e2f4
gene id: 244447:e2f4
uniprot id: A0A3P8X0N1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the E2F/DP family.
messages: Nucleus

244447:LOC103390465
gene id: 244447:LOC103390465
uniprot id: A0A3P8UQ42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATR family.
messages: Membrane

244447:LOC103391886
gene id: 244447:LOC103391886
uniprot id: A0A3P8V4L0
names: Similarity
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.

244447:LOC103388113
gene id: 244447:LOC103388113
uniprot id: A0A3P8UFM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metaxin family.
messages: Membrane
messages: Mitochondrion outer membrane

244447:LOC103384550
gene id: 244447:LOC103384550
uniprot id: A0A3P8WMF9
uniprot id: A0A3P8WSP4
names: Subcellular Location Annotation
messages: centrosome
messages: perinuclear region

244447:gmpr
gene id: 244447:gmpr
uniprot id: A0A3P8WSP8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family. GuaC type 1 subfamily.
messages: Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.
messages: Homotetramer.

244447:LOC103393268
gene id: 244447:LOC103393268
uniprot id: A0A3P8WP34
names: Similarity
messages: Belongs to the FAM20 family.

244447:LOC103382040
gene id: 244447:LOC103382040
uniprot id: A0A3P8WT26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VKOR family.
messages: Endoplasmic reticulum membrane
messages: Membrane

244447:LOC103395995
gene id: 244447:LOC103395995
uniprot id: A0A3P8WAR3
names: Similarity
messages: Belongs to the mTERF family.

244447:LOC103397013
gene id: 244447:LOC103397013
uniprot id: A0A3P8VNP6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SNF5 family.
messages: Component of the multiprotein chromatin-remodeling complexes SWI/SNF.
messages: Nucleus

244447:LOC103376812
gene id: 244447:LOC103376812
uniprot id: A0A3P8VG94
names: Similarity
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

244447:zc3h12b
gene id: 244447:zc3h12b
uniprot id: A0A3P8W1N2
names: Similarity
messages: Belongs to the ZC3H12 family.

244447:slc43a1
gene id: 244447:slc43a1
uniprot id: A0A3P8VCY3
names: Subcellular Location Annotation
messages: Membrane

244447:LOC103381039
gene id: 244447:LOC103381039
uniprot id: A0A0U1T8P4
names: Subcellular Location Annotation
messages: Nucleus

244447:LOC103382932
gene id: 244447:LOC103382932
uniprot id: A0A3P8VYL5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ALG10 glucosyltransferase family.
messages: Membrane

244447:LOC103380289
gene id: 244447:LOC103380289
uniprot id: A0A3P8VBW4
names: Cofactor
names: Similarity
messages: Belongs to the 5'(3')-deoxyribonucleotidase family.
messages: Binds 1 Mg(2+) ion per subunit.

244447:LOC103382311
gene id: 244447:LOC103382311
uniprot id: A0A3P8UH56
names: Similarity
messages: Belongs to the globin family.

244447:nptn
gene id: 244447:nptn
uniprot id: A0A3P8VB79
names: Subcellular Location Annotation
messages: Membrane

244447:tat
gene id: 244447:tat
uniprot id: A0A3P8UJG7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.
messages: Transaminase involved in tyrosine breakdown. Converts tyrosine to p-hydroxyphenylpyruvate.

244447:ephb3
gene id: 244447:ephb3
uniprot id: A0A3P8WBJ5
uniprot id: A0A3P8WC33
uniprot id: A0A3P8WH88
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

244447:LOC103381864
gene id: 244447:LOC103381864
uniprot id: A0A3P8W9M8
names: Similarity
messages: Belongs to the proteasome subunit S9 family.

244447:LOC103396557
gene id: 244447:LOC103396557
uniprot id: A0A3P8WLG3
names: Similarity
messages: Belongs to the TPR family.

244447:wnt9b
gene id: 244447:wnt9b
uniprot id: A0A3P8X683
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

244447:LOC103382720
gene id: 244447:LOC103382720
uniprot id: A0A3P8V9M5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acyl-CoA reductase family.
messages: Catalyzes the reduction of fatty acyl-CoA to fatty alcohols.
messages: Peroxisome membrane

244447:psma8
gene id: 244447:psma8
uniprot id: A0A3P8VR36
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Cytoplasm
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.

244447:LOC103396219
gene id: 244447:LOC103396219
uniprot id: A0A3P8VQB3
names: Subcellular Location Annotation
messages: Membrane

244447:ak1
gene id: 244447:ak1
uniprot id: A0A3P8WKN6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family. AK1 subfamily.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Also displays broad nucleoside diphosphate kinase activity. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Monomer.

244447:LOC103399964
gene id: 244447:LOC103399964
uniprot id: A0A3P8UXZ2
names: Similarity
messages: Belongs to the perilipin family.

244447:eif3a
gene id: 244447:eif3a
uniprot id: A0A3P8VJP6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit A family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M.
messages: Cytoplasm
messages: RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.

244447:LOC103381205
gene id: 244447:LOC103381205
uniprot id: A0A3P8V027
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the protein prenyltransferase subunit beta family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the transfer of a farnesyl moiety from farnesyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins. The beta subunit is responsible for peptide-binding.
messages: Heterodimer of an alpha and a beta subunit.

244447:impdh2
gene id: 244447:impdh2
uniprot id: A0A3P8V5N6
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.
messages: Nucleus

244447:vps13b
gene id: 244447:vps13b
uniprot id: A0A3P8VEX7
names: Similarity
messages: Belongs to the VPS13 family.

244447:LOC103387361
gene id: 244447:LOC103387361
uniprot id: A0A3P8UNB6
names: Subcellular Location Annotation
messages: Nucleus

244447:fam91a1
gene id: 244447:fam91a1
uniprot id: A0A3P8WPE4
names: Similarity
messages: Belongs to the FAM91 family.

244447:LOC103378707
gene id: 244447:LOC103378707
uniprot id: A0A3P8UMX1
uniprot id: A0A3P8UP06
names: Function
names: Similarity
messages: Belongs to the ferritin family.
messages: Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.

244447:LOC103387093
gene id: 244447:LOC103387093
uniprot id: A0A3P8UZZ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament.
messages: Belongs to the actin family. ARP2 subfamily.
messages: Component of the Arp2/3 complex.
messages: cytoskeleton

244447:smdt1
gene id: 244447:smdt1
uniprot id: A0A3P8VD11
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMDT1/EMRE family.
messages: Component of the uniplex complex. Interacts (via the transmembrane region) with MCU (via the first transmembrane region); the interaction is direct.
messages: Essential regulatory subunit of the mitochondrial calcium uniporter complex (uniplex), a complex that mediates calcium uptake into mitochondria.
messages: Membrane
messages: Mitochondrion inner membrane

244447:phkb
gene id: 244447:phkb
uniprot id: A0A3P8VHR4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphorylase b kinase regulatory chain family.
messages: Cell membrane
messages: Membrane
messages: Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I.

244447:LOC103387033
gene id: 244447:LOC103387033
uniprot id: A0A3P8UUH4
names: Subcellular Location Annotation
messages: Nucleus

244447:odf2
gene id: 244447:odf2
uniprot id: A0A3P8URD5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ODF2 family.
messages: centrosome

244447:trim32
gene id: 244447:trim32
uniprot id: A0A3P8WJN9
names: Similarity
messages: Belongs to the TRIM/RBCC family.

244447:p2ry2
gene id: 244447:p2ry2
uniprot id: A0A3P8WVW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

244447:LOC103395587
gene id: 244447:LOC103395587
uniprot id: A0A3P8WWH6
names: Similarity
messages: Belongs to the nucleoplasmin family.

244447:LOC103388636
gene id: 244447:LOC103388636
uniprot id: A0A3P8VNT1
uniprot id: A0A3P8VP40
uniprot id: A0A3P8VUD2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the spire family.
messages: Cell membrane
messages: Cytoplasmic vesicle membrane
messages: Membrane
messages: cytoskeleton

244447:ercc4
gene id: 244447:ercc4
uniprot id: A0A3P8WV94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XPF family.
messages: Nucleus

244447:LOC103389104
gene id: 244447:LOC103389104
uniprot id: A0A3P8WGS6
names: Similarity
messages: Belongs to the Niban family.

244447:LOC103393529
gene id: 244447:LOC103393529
uniprot id: A0A3P8VY54
names: Similarity
messages: Belongs to the TMEM106 family.

244447:LOC103388203
gene id: 244447:LOC103388203
uniprot id: A0A3P8UMG4
names: Similarity
messages: Belongs to the type I cytokine receptor family. Type 3 subfamily.

244447:LOC103387641
gene id: 244447:LOC103387641
uniprot id: A0A3P8WCV2
names: Similarity
messages: Belongs to the aldolase class II family. Adducin subfamily.

244447:lnpk
gene id: 244447:lnpk
uniprot id: A0A3P8V3P2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the lunapark family.
messages: Endoplasmic reticulum membrane
messages: Homodimer; homodimerization requires the C4-type zinc finger motif and decreases during mitosis in a phosphorylation-dependent manner.
messages: Plays a role in determining ER morphology.
messages: The C4-type zinc finger motif is necessary both for its ER three-way tubular junction localization and formation.

244447:pdx1
gene id: 244447:pdx1
uniprot id: A0A3P8WE93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus

244447:cebpa
gene id: 244447:cebpa
uniprot id: A0A7S9VKZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. C/EBP subfamily.
messages: Nucleus

244447:LOC103398275
gene id: 244447:LOC103398275
uniprot id: A0A3P8WDB5
names: Similarity
messages: Belongs to the peptidase M1 family.

244447:LOC103386315
gene id: 244447:LOC103386315
uniprot id: A0A3P8VJB6
names: Similarity
messages: Belongs to the bZIP family. Maf subfamily.

244447:LOC103382808
gene id: 244447:LOC103382808
uniprot id: A0A3P8W459
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Putative Notch ligand involved in the mediation of Notch signaling.

244447:tchp
gene id: 244447:tchp
uniprot id: A0A3P8VEI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCHP family.
messages: cytoskeleton

244447:LOC103386225
gene id: 244447:LOC103386225
uniprot id: A0A3P8V9K0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Musashi family.
messages: Cytoplasm

244447:LOC103398229
gene id: 244447:LOC103398229
uniprot id: A0A3P8W5L1
names: Similarity
messages: Belongs to the indoleamine 2,3-dioxygenase family.

244447:LOC103391531
gene id: 244447:LOC103391531
uniprot id: A0A3P8W2I5
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

244447:washc3
gene id: 244447:washc3
uniprot id: A0A3P8V8V1
names: Similarity
messages: Belongs to the CCDC53 family.

244447:msx1
gene id: 244447:msx1
uniprot id: A0A3P8VFS8
names: Subcellular Location Annotation
messages: Nucleus

244447:LOC103387887
gene id: 244447:LOC103387887
uniprot id: A0A3P8WQZ8
names: Subcellular Location Annotation
messages: Nucleus

244447:LOC103382064
gene id: 244447:LOC103382064
uniprot id: A0A3P8WXS8
names: Similarity
messages: Belongs to the CDR2 family.

244447:LOC103387000
gene id: 244447:LOC103387000
uniprot id: A0A3P8ULC3
names: Similarity
messages: Belongs to the myozenin family.

244447:stxbp2
gene id: 244447:stxbp2
uniprot id: A0A3P8VUG2
names: Similarity
messages: Belongs to the STXBP/unc-18/SEC1 family.

244447:LOC103386529
gene id: 244447:LOC103386529
uniprot id: A0A3P8WGC4
names: Subcellular Location Annotation
messages: Membrane

244447:tfcp2
gene id: 244447:tfcp2
uniprot id: A0A3P8WB47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the grh/CP2 family. CP2 subfamily.
messages: Nucleus

244447:ppil4
gene id: 244447:ppil4
uniprot id: A0A3P8WBB4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cyclophilin-type PPIase family. PPIL4 subfamily.
messages: Nucleus
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

244447:dync1i2
gene id: 244447:dync1i2
uniprot id: A0A3P8VEP3
names: Similarity
messages: Belongs to the dynein intermediate chain family.

244447:jph3
gene id: 244447:jph3
uniprot id: A0A3P8W5J5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the junctophilin family.
messages: Endoplasmic reticulum membrane
messages: Membrane

244447:LOC103378659
gene id: 244447:LOC103378659
uniprot id: A0A3P8UII6
names: Subcellular Location Annotation
messages: Membrane

244447:sgms2
gene id: 244447:sgms2
uniprot id: A0A3P8UQC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sphingomyelin synthase family.
messages: Membrane

244447:LOC103391910
gene id: 244447:LOC103391910
uniprot id: A0A3P8V806
names: Subcellular Location Annotation
messages: Nucleus

244447:clic4
gene id: 244447:clic4
uniprot id: A0A3P8UHN9
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel CLIC family.
messages: Cytoplasm
messages: Members of this family may change from a globular, soluble state to a state where the N-terminal domain is inserted into the membrane and functions as chloride channel. A conformation change of the N-terminal domain is thought to expose hydrophobic surfaces that trigger membrane insertion.
messages: Membrane

244447:stard5
gene id: 244447:stard5
uniprot id: A0A3P8V109
names: Function
messages: May be involved in the intracellular transport of sterols or other lipids. May bind cholesterol or other sterols.

244447:LOC103384998
gene id: 244447:LOC103384998
uniprot id: A0A3P8WU62
names: Subcellular Location Annotation
messages: Membrane

244447:slc22a2
gene id: 244447:slc22a2
uniprot id: A0A3P8V337
names: Similarity
messages: Belongs to the major facilitator (TC 2.A.1) superfamily. Organic cation transporter (TC 2.A.1.19) family.

244447:cd63
gene id: 244447:cd63
uniprot id: A0A3P8X5V1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

244447:gk5
gene id: 244447:gk5
uniprot id: A0A3P8WKJ1
names: Similarity
messages: Belongs to the FGGY kinase family.

244447:osbpl7
gene id: 244447:osbpl7
uniprot id: A0A3P8W9G3
names: Similarity
messages: Belongs to the OSBP family.

244447:hint3
gene id: 244447:hint3
uniprot id: A0A3P8VNQ0
names: Similarity
messages: Belongs to the HINT family.

244447:LOC103379422
gene id: 244447:LOC103379422
uniprot id: A0A3P8W0S2
names: Subcellular Location Annotation
messages: Membrane

244447:LOC103388168
gene id: 244447:LOC103388168
uniprot id: A0A3P8UI09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

244447:LOC103380095
gene id: 244447:LOC103380095
uniprot id: A0A3P8V1Z7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM53 family.
messages: Membrane
messages: Nucleus outer membrane

244447:zadh2
gene id: 244447:zadh2
uniprot id: A0A3P8VUI4
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.

244447:tada2b
gene id: 244447:tada2b
uniprot id: A0A3P8WTP3
names: Subcellular Location Annotation
messages: Nucleus

244447:LOC103378004
gene id: 244447:LOC103378004
uniprot id: A0A3P8VH13
names: Subcellular Location Annotation
messages: Membrane

244447:LOC103384129
gene id: 244447:LOC103384129
uniprot id: A0A3P8VY78
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complexin/synaphin family.
messages: Synapse

244447:LOC103387794
gene id: 244447:LOC103387794
uniprot id: A0A3P8WPA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
messages: Cytoplasm

244447:LOC103388050
gene id: 244447:LOC103388050
uniprot id: A0A3P8WZ20
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

244447:LOC103394292
gene id: 244447:LOC103394292
uniprot id: A0A3P8W930
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anion exchanger (TC 2.A.31) family.
messages: Membrane

244447:slc4a11
gene id: 244447:slc4a11
uniprot id: A0A3P8W943
uniprot id: A0A3P8WEE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anion exchanger (TC 2.A.31) family.
messages: Membrane

244447:fli1
gene id: 244447:fli1
uniprot id: A0A3P8UTM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

244447:st3gal3
gene id: 244447:st3gal3
uniprot id: A0A3P8UQR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

244447:dtd1
gene id: 244447:dtd1
uniprot id: A0A3P8VRR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DTD family.
messages: Cytoplasm

244447:LOC103392487
gene id: 244447:LOC103392487
uniprot id: A0A3P8WV53
names: Caution
names: Similarity
messages: Belongs to the neuropilin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

244447:LOC103377410
gene id: 244447:LOC103377410
uniprot id: A0A3P8UQH5
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

244447:bcl7b
gene id: 244447:bcl7b
uniprot id: A0A3P8WUG5
names: Similarity
messages: Belongs to the BCL7 family.

244447:LOC103384172
gene id: 244447:LOC103384172
uniprot id: A0A3P8W7J6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LRRC8 family.
messages: Cell membrane
messages: Membrane

244447:mgst1
gene id: 244447:mgst1
uniprot id: A0A3P8WGH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAPEG family.
messages: Membrane

244447:LOC103383463
gene id: 244447:LOC103383463
uniprot id: A0A3P8WEB7
names: Similarity
messages: Belongs to the D-glutamate cyclase family.

244447:smpd2
gene id: 244447:smpd2
uniprot id: A0A3P8WEH4
names: Similarity
messages: Belongs to the neutral sphingomyelinase family.

244447:dars2
gene id: 244447:dars2
uniprot id: A0A3P8WQ81
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.

244447:mocos
gene id: 244447:mocos
uniprot id: A0A3P8VQF3
uniprot id: A0A3P8VQI7
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. MOCOS subfamily.
messages: Sulfurates the molybdenum cofactor. Sulfation of molybdenum is essential for xanthine dehydrogenase (XDH) and aldehyde oxidase (ADO) enzymes in which molybdenum cofactor is liganded by 1 oxygen and 1 sulfur atom in active form.

244447:LOC103396005
gene id: 244447:LOC103396005
uniprot id: A0A3P8WED4
uniprot id: A0A3P8WJC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adaptor complexes small subunit family.
messages: Cytoplasmic vesicle membrane
messages: Golgi apparatus
messages: clathrin-coated pit

244447:banf1
gene id: 244447:banf1
uniprot id: A0A3P8VU86
names: Subcellular Location Annotation
messages: Nucleus

244447:LOC103381580
gene id: 244447:LOC103381580
uniprot id: A0A3P8VCW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alpha/beta interferon family.
messages: Secreted

244447:smim12
gene id: 244447:smim12
uniprot id: A0A3P8W7D0
names: Similarity
messages: Belongs to the SMIM12 family.

244447:mpp7
gene id: 244447:mpp7
uniprot id: A0A3P8WAS1
names: Similarity
messages: Belongs to the MAGUK family.

244447:creb3l4
gene id: 244447:creb3l4
uniprot id: A0A3P8W4T4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. ATF subfamily.
messages: Endoplasmic reticulum membrane
messages: Membrane

244447:LOC103393595
gene id: 244447:LOC103393595
uniprot id: A0A3P8W3X0
names: Similarity
messages: Belongs to the MAGUK family.

244447:vgll4
gene id: 244447:vgll4
uniprot id: A0A3P8X3N5
uniprot id: A0A3P8X457
names: Function
names: Similarity
messages: Belongs to the vestigial family.
messages: May act as a specific coactivator for the mammalian TEFs.

244447:LOC103383009
gene id: 244447:LOC103383009
uniprot id: A0A3P8WFP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAPEG family.
messages: Membrane

244447:LOC103380453
gene id: 244447:LOC103380453
uniprot id: A0A3P8W761
names: Similarity
messages: Belongs to the pyruvate kinase family.

244447:LOC103382992
gene id: 244447:LOC103382992
uniprot id: A0A3P8WK58
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Rab GDI family.
messages: Cytoplasm
messages: Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP.

244447:hs3st2
gene id: 244447:hs3st2
uniprot id: A0A3P8VM89
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

244447:stip1
gene id: 244447:stip1
uniprot id: A0A3P8WHY0
uniprot id: A0A3P8WI00
names: Subcellular Location Annotation
messages: Cytoplasm

244447:LOC103397038
gene id: 244447:LOC103397038
uniprot id: A0A3P8VRF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PPP phosphatase family. PP-1 subfamily.
messages: Cleavage furrow
messages: Cytoplasm
messages: Midbody

244447:sult4a1
gene id: 244447:sult4a1
uniprot id: A0A3P8URJ5
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

244447:LOC103378618
gene id: 244447:LOC103378618
uniprot id: A0A3P8UB21
names: Subcellular Location Annotation
messages: PML body
messages: autophagosome
messages: cytosol

244447:LOC103383875
gene id: 244447:LOC103383875
uniprot id: A0A3P8VP18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAF1 family.
messages: Nucleus

244447:LOC103397438
gene id: 244447:LOC103397438
uniprot id: A0A3P8VUW9
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

244447:LOC103393901
gene id: 244447:LOC103393901
uniprot id: A0A3P8WFT4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tim44 family.
messages: Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner.
messages: Mitochondrion inner membrane

244447:LOC107988080
gene id: 244447:LOC107988080
uniprot id: A0A3P8VKK7
names: Similarity
messages: Belongs to the IL-17 family.

244447:zdhhc6
gene id: 244447:zdhhc6
uniprot id: A0A3P8VDC5
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

244447:LOC103394023
gene id: 244447:LOC103394023
uniprot id: A0A3P8WD92
names: Similarity
messages: Belongs to the alkaline phosphatase family.

244447:phkg1
gene id: 244447:phkg1
uniprot id: A0A3P8VPG7
names: Similarity
names: Subunit
messages: Belongs to the protein kinase superfamily.
messages: Hexadecamer of 4 heterotetramers, each composed of alpha, beta, gamma, and delta subunits. Alpha (PHKA1 or PHKA2) and beta (PHKB) are regulatory subunits, gamma (PHKG1 or PHKG2) is the catalytic subunit, and delta is calmodulin.

244447:actn3
gene id: 244447:actn3
uniprot id: A0A3P8UDL4
names: Similarity
messages: Belongs to the alpha-actinin family.

244447:glb1
gene id: 244447:glb1
uniprot id: A0A3P8UTK1
names: Similarity
messages: Belongs to the glycosyl hydrolase 35 family.

244447:LOC103383024
gene id: 244447:LOC103383024
uniprot id: A0A3P8WEK0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Interacts with PPIF; the interaction is impaired by CsA.
messages: Membrane
messages: Mitochondrion inner membrane

244447:LOC103393206
gene id: 244447:LOC103393206
uniprot id: A0A3P8WK35
names: Similarity
messages: Belongs to the CDR2 family.

244447:bmp4
gene id: 244447:bmp4
uniprot id: A0A0U1WUT6
names: Similarity
messages: Belongs to the TGF-beta family.

244447:LOC103393168
gene id: 244447:LOC103393168
uniprot id: A0A3P8WQD5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAVIN family.
messages: caveola

244447:foxf1
gene id: 244447:foxf1
uniprot id: A0A3P8W6T6
names: Subcellular Location Annotation
messages: Nucleus

244447:LOC103393680
gene id: 244447:LOC103393680
uniprot id: A0A3P8W960
uniprot id: A0A3P8WBJ3
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

244447:pappa
gene id: 244447:pappa
uniprot id: A0A3P8WNL9
names: Caution
names: Similarity
messages: Belongs to the peptidase M43B family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

244447:st6gal2
gene id: 244447:st6gal2
uniprot id: A0A3P8UTH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

244447:LOC103397062
gene id: 244447:LOC103397062
uniprot id: A0A3P8VVL3
names: Subcellular Location Annotation
messages: Membrane

244447:aldh6a1
gene id: 244447:aldh6a1
uniprot id: A0A3P8UL50
names: Function
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.
messages: Plays a role in valine and pyrimidine metabolism. Binds fatty acyl-CoA.

244447:LOC103377845
gene id: 244447:LOC103377845
uniprot id: A0A3P8V3J3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TGF-beta family.
messages: Homodimer; disulfide-linked.
messages: Transforming growth factor beta-1 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-1 (TGF-beta-1) chains, which constitute the regulatory and active subunit of TGF-beta-1, respectively.
messages: extracellular matrix

244447:LOC103395964
gene id: 244447:LOC103395964
uniprot id: A0A3P8W9A0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

244447:got1
gene id: 244447:got1
uniprot id: A0A3P8V3M9
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.
messages: In eukaryotes there are cytoplasmic, mitochondrial and chloroplastic isozymes.

244447:LOC103385474
gene id: 244447:LOC103385474
uniprot id: A0A3P8X5P9
names: Subcellular Location Annotation
messages: cytoskeleton

244447:LOC103387667
gene id: 244447:LOC103387667
uniprot id: A0A3P8WAM0
names: Similarity
messages: Belongs to the acylphosphatase family.

244447:LOC103379373
gene id: 244447:LOC103379373
uniprot id: A0A3P8VWL9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

244447:tbx2
gene id: 244447:tbx2
uniprot id: A0A3P8UXS1
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

244447:mrps23
gene id: 244447:mrps23
uniprot id: A0A3P8UPF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mS23 family.
messages: Mitochondrion

244447:LOC103386858
gene id: 244447:LOC103386858
uniprot id: A0A3P8UFL8
names: Subcellular Location Annotation
messages: Membrane

244447:postn
gene id: 244447:postn
uniprot id: A0A3P8WTG1
names: Subcellular Location Annotation
messages: extracellular matrix

244447:nagk
gene id: 244447:nagk
uniprot id: A0A3P8WI01
names: Similarity
messages: Belongs to the eukaryotic-type N-acetylglucosamine kinase family.

244447:pcyt1a
gene id: 244447:pcyt1a
uniprot id: T2BAQ6
names: Function
names: Similarity
messages: Belongs to the cytidylyltransferase family.
messages: Catalyzes the key rate-limiting step in the CDP-choline pathway for phosphatidylcholine biosynthesis.

244447:LOC103393380
gene id: 244447:LOC103393380
uniprot id: A0A3P8VAH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

244447:LOC103381942
gene id: 244447:LOC103381942
uniprot id: A0A3P8WM43
names: Similarity
messages: Belongs to the small GTPase superfamily. Arf family.
messages: Belongs to the small GTPase superfamily. SAR1 family.

244447:LOC103380211
gene id: 244447:LOC103380211
uniprot id: A0A3P8V5U9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

244447:LOC103386044
gene id: 244447:LOC103386044
uniprot id: A0A3P8UTQ5
names: Similarity
messages: Belongs to the peptidase M10A family.

244447:LOC103381621
gene id: 244447:LOC103381621
uniprot id: A0A3P8VKC7
names: Subcellular Location Annotation
messages: Membrane

244447:utp11
gene id: 244447:utp11
uniprot id: A0A3P8X1T0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UTP11 family.
messages: Component of the ribosomal small subunit (SSU) processome.
messages: Involved in nucleolar processing of pre-18S ribosomal RNA.
messages: nucleolus

244447:rpa1
gene id: 244447:rpa1
uniprot id: A0A3P8VYZ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.
messages: Belongs to the replication factor A protein 1 family.
messages: Component of the heterotrimeric canonical replication protein A complex (RPA).
messages: PML body

244447:bpgm
gene id: 244447:bpgm
uniprot id: A0A3P8W7E0
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.

244447:LOC103396997
gene id: 244447:LOC103396997
uniprot id: A0A3P8VID7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AB hydrolase superfamily. Lipase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

244447:cops3
gene id: 244447:cops3
uniprot id: A0A3P8WYG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSN3 family.
messages: Cytoplasm
messages: Nucleus

244447:nkx3-2
gene id: 244447:nkx3-2
uniprot id: A0A3P8UVW9
names: Subcellular Location Annotation
messages: Nucleus

244447:vps37b
gene id: 244447:vps37b
uniprot id: A0A3P8W3Y0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS37 family.
messages: Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. May be involved in cell growth and differentiation.
messages: Endosome membrane
messages: Late endosome membrane

244447:acvr1c
gene id: 244447:acvr1c
uniprot id: A0A3P8VY56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Membrane

244447:slc35b3
gene id: 244447:slc35b3
uniprot id: A0A3P8VQG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide-sugar transporter family. SLC35B subfamily.
messages: Membrane

244447:bloc1s6
gene id: 244447:bloc1s6
uniprot id: A0A3P8W2Q3
names: Function
names: Similarity
messages: Belongs to the BLOC1S6 family.
messages: Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. May play a role in intracellular vesicle trafficking, particularly in the vesicle-docking and fusion process.

244447:fam193b
gene id: 244447:fam193b
uniprot id: A0A3P8W4A9
names: Similarity
messages: Belongs to the FAM193 family.

244447:urad
gene id: 244447:urad
uniprot id: A0A3P8WH42
names: Function
names: Similarity
messages: Belongs to the OHCU decarboxylase family.
messages: Catalyzes the stereoselective decarboxylation of 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU) to (S)-allantoin.

244447:LOC103378056
gene id: 244447:LOC103378056
uniprot id: A0A3P8VEM6
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

244447:LOC103385081
gene id: 244447:LOC103385081
uniprot id: A0A3P8V638
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tachykinin family.
messages: Secreted

244447:LOC103379795
gene id: 244447:LOC103379795
uniprot id: A0A3P8UGT7
uniprot id: A0A3P8UK92
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

244447:LOC103396450
gene id: 244447:LOC103396450
uniprot id: A0A3P8W6Z8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calycin superfamily. Lipocalin family.
messages: Secreted

244447:cd164
gene id: 244447:cd164
uniprot id: A0A3P8WS11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CD164 family.
messages: Membrane

244447:gsto1
gene id: 244447:gsto1
uniprot id: A0A3P8WCD5
names: Function
names: Similarity
messages: Belongs to the GST superfamily. Omega family.
messages: Exhibits glutathione-dependent thiol transferase activity. Has high dehydroascorbate reductase activity and may contribute to the recycling of ascorbic acid. Participates in the biotransformation of inorganic arsenic and reduces monomethylarsonic acid (MMA).

244447:LOC103393624
gene id: 244447:LOC103393624
uniprot id: A0A3P8W8M9
uniprot id: A0A3P8WBE6
uniprot id: A0A3P8WBF2
uniprot id: A0A3P8WBR2
uniprot id: A0A3P8WBT0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CTF/NF-I family.
messages: Binds DNA as a homodimer.
messages: Nucleus
messages: Recognizes and binds the palindromic sequence 5'-TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication.

244447:timm8b
gene id: 244447:timm8b
uniprot id: A0A3P8V0M8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the small Tim family.
messages: Heterohexamer.
messages: Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.
messages: Mitochondrion inner membrane
messages: The twin CX3C motif contains 4 conserved Cys residues that form 2 disulfide bonds in the mitochondrial intermembrane space.

244447:LOC103387004
gene id: 244447:LOC103387004
uniprot id: A0A3P8ULG8
names: Subcellular Location Annotation
messages: Membrane

244447:actb
gene id: 244447:actb
uniprot id: A0A0A7DHF9
names: Similarity
messages: Belongs to the actin family.

244447:acat1
gene id: 244447:acat1
uniprot id: A0A3P8W5U7
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

244447:crebl2
gene id: 244447:crebl2
uniprot id: A0A3P8V074
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. ATF subfamily.
messages: Nucleus

244447:haao
gene id: 244447:haao
uniprot id: A0A3P8UCY1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 3-HAO family.
messages: Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

244447:LOC103385929
gene id: 244447:LOC103385929
uniprot id: A0A3P8UWG0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ARPC4 family.
messages: Cell projection
messages: Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament.
messages: cytoskeleton

244447:phpt1
gene id: 244447:phpt1
uniprot id: A0A3P8WYD4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the janus family.
messages: Cytoplasm
messages: Exhibits phosphohistidine phosphatase activity.
messages: Monomer.

244447:LOC103388948
gene id: 244447:LOC103388948
uniprot id: A0A3P8W961
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Polycomblike family.
messages: Nucleus

244447:mrps30
gene id: 244447:mrps30
uniprot id: A0A3P8WSA0
names: Subcellular Location Annotation
messages: Mitochondrion

244447:txnl4a
gene id: 244447:txnl4a
uniprot id: A0A3P8VHN8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DIM1 family.
messages: Nucleus
messages: Plays role in pre-mRNA splicing.

244447:LOC103383449
gene id: 244447:LOC103383449
uniprot id: A0A3P8ULL7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Membrane
messages: Retinol dehydrogenase with a clear preference for NADP. Converts all-trans-retinal to all-trans-retinol. May play a role in the regeneration of visual pigment at high light intensity.

244447:LOC103396390
gene id: 244447:LOC103396390
uniprot id: A0A3P8VW96
uniprot id: D7UEQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

244447:LOC103379655
gene id: 244447:LOC103379655
uniprot id: A0A3P8X6Q4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acid desaturase CarF family.
messages: Membrane

244447:gli1
gene id: 244447:gli1
uniprot id: A0A3P8VX49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GLI C2H2-type zinc-finger protein family.
messages: Nucleus

244447:eef1b2
gene id: 244447:eef1b2
uniprot id: A0A3P8VIR9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the EF-1-beta/EF-1-delta family.
messages: EF-1 is composed of 4 subunits: alpha, beta, delta, and gamma.
messages: EF-1-beta and EF-1-delta stimulate the exchange of GDP bound to EF-1-alpha to GTP.

244447:nrn1l
gene id: 244447:nrn1l
uniprot id: A0A3P8W693
names: Similarity
messages: Belongs to the neuritin family.

244447:dr1
gene id: 244447:dr1
uniprot id: A0A3P8VK67
names: Similarity
messages: Belongs to the NC2 beta/DR1 family.

244447:rnf111
gene id: 244447:rnf111
uniprot id: A0A3P8UJ79
uniprot id: A0A3P8UP41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Arkadia family.
messages: PML body

244447:LOC103382950
gene id: 244447:LOC103382950
uniprot id: A0A3P8W8V8
names: Similarity
messages: Belongs to the complex I LYR family.

244447:chrnb1
gene id: 244447:chrnb1
uniprot id: A0A3P8W894
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

244447:adgra2
gene id: 244447:adgra2
uniprot id: A0A3P8W3P0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily.
messages: Membrane

244447:ptgr2
gene id: 244447:ptgr2
uniprot id: A0A3P8V6R4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NADP-dependent oxidoreductase L4BD family.
messages: Cytoplasm
messages: Monomer.

244447:prpf19
gene id: 244447:prpf19
uniprot id: A0A3P8VLL9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat PRP19 family.
messages: Homotetramer.
messages: Lipid droplet
messages: Ubiquitin-protein ligase which is mainly involved pre-mRNA splicing and DNA repair. Required for pre-mRNA splicing as component of the spliceosome.
messages: nucleoplasm

244447:LOC103396882
gene id: 244447:LOC103396882
uniprot id: A0A3P8VF27
names: Subcellular Location Annotation
messages: Nucleus

244447:tk1
gene id: 244447:tk1
uniprot id: A0A3P8WD78
names: Similarity
messages: Belongs to the thymidine kinase family.

244447:ano5
gene id: 244447:ano5
uniprot id: A0A3P8V5L9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anoctamin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

244447:wnt9a
gene id: 244447:wnt9a
uniprot id: A0A3P8W3U4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

244447:LOC103381527
gene id: 244447:LOC103381527
uniprot id: A0A3P8VE68
uniprot id: A0A3P8VK01
names: Subcellular Location Annotation
messages: Z line

244447:LOC103384139
gene id: 244447:LOC103384139
uniprot id: A0A3P8W524
names: Subcellular Location Annotation
messages: Nucleus

244447:tonsl
gene id: 244447:tonsl
uniprot id: A0A3P8UT29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tonsoku family.
messages: Chromosome

244447:LOC103396722
gene id: 244447:LOC103396722
uniprot id: A0A3P8X5E8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

244447:LOC103383768
gene id: 244447:LOC103383768
uniprot id: A0A3P8VLZ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family. SLC25A38 subfamily.
messages: Membrane
messages: Mitochondrial glycine transporter that imports glycine into the mitochondrial matrix. Plays an important role in providing glycine for the first enzymatic step in heme biosynthesis, the condensation of glycine with succinyl-CoA to produce 5-aminolevulinate (ALA) in the miochondrial matrix. Required during erythropoiesis.
messages: Mitochondrion inner membrane

244447:LOC103397564
gene id: 244447:LOC103397564
uniprot id: A0A3P8WF49
names: Similarity
messages: Belongs to the IUNH family.

244447:fen1
gene id: 244447:fen1
uniprot id: A0A3P8VRD3
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XPG/RAD2 endonuclease family. FEN1 subfamily.
messages: Binds 2 magnesium ions per subunit. They probably participate in the reaction catalyzed by the enzyme. May bind an additional third magnesium ion after substrate binding.
messages: Interacts with PCNA. Three molecules of FEN1 bind to one PCNA trimer with each molecule binding to one PCNA monomer. PCNA stimulates the nuclease activity without altering cleavage specificity.
messages: Mitochondrion
messages: Phosphorylated. Phosphorylation upon DNA damage induces relocalization to the nuclear plasma.
messages: Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site-terminated flap. Acts as a genome stabilization factor that prevents flaps from equilibrating into structures that lead to duplications and deletions. Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA, and exhibits RNase H activity. Also involved in replication and repair of rDNA and in repairing mitochondrial DNA.
messages: nucleolus
messages: nucleoplasm

244447:ptpn14
gene id: 244447:ptpn14
uniprot id: A0A3P8X387
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class subfamily.
messages: cytoskeleton

244447:LOC103392616
gene id: 244447:LOC103392616
uniprot id: A0A3P8X678
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

244447:polr3d
gene id: 244447:polr3d
uniprot id: A0A3P8VB56
names: Subcellular Location Annotation
messages: Nucleus

244447:LOC103386106
gene id: 244447:LOC103386106
uniprot id: A0A3P8UZ24
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HRG family.
messages: Endosome membrane
messages: Heme transporter that regulates intracellular heme availability through the endosomal or lysosomal compartment.
messages: Lysosome membrane
messages: Membrane

244447:col4a5
gene id: 244447:col4a5
uniprot id: A0A3P8UCZ0
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a 'chicken-wire' meshwork together with laminins, proteoglycans and entactin/nidogen.
messages: basement membrane

244447:st3gal1
gene id: 244447:st3gal1
uniprot id: A0A3P8W3A7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

244447:LOC103377267
gene id: 244447:LOC103377267
uniprot id: A0A3P8WL37
names: Similarity
messages: Belongs to the peptidase M14 family.

244447:c20h1orf123
gene id: 244447:c20h1orf123
uniprot id: A0A3P8VQZ5
names: Similarity
messages: Belongs to the UPF0587 family.

244447:ppil2
gene id: 244447:ppil2
uniprot id: A0A3P8WVM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cyclophilin-type PPIase family. PPIL2 subfamily.
messages: Nucleus

244447:LOC103397783
gene id: 244447:LOC103397783
uniprot id: A0A3P8WUS1
names: Subcellular Location Annotation
messages: Membrane

244447:LOC103396574
gene id: 244447:LOC103396574
uniprot id: A0A3P8X1U1
names: Subcellular Location Annotation
messages: Nucleus

244447:surf6
gene id: 244447:surf6
uniprot id: A0A3P8WBE7
names: Similarity
messages: Belongs to the SURF6 family.

244447:LOC103392643
gene id: 244447:LOC103392643
uniprot id: A0A3P8X349
uniprot id: A0A3P8X5R3
names: Subcellular Location Annotation
messages: Secreted
messages: Synapse

244447:LOC103382346
gene id: 244447:LOC103382346
uniprot id: A0A3P8UCN5
names: Function
names: Similarity
messages: Belongs to the parvalbumin family.
messages: In muscle, parvalbumin is thought to be involved in relaxation after contraction. It binds two calcium ions.

244447:LOC103389371
gene id: 244447:LOC103389371
uniprot id: A0A3P8USE2
names: Similarity
messages: Belongs to the intermediate filament family.

244447:mrpl32
gene id: 244447:mrpl32
uniprot id: A0A3P8VTV9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

244447:LOC103383736
gene id: 244447:LOC103383736
uniprot id: A0A3P8V8D4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Su(H) family.
messages: Nucleus

244447:g6pc3
gene id: 244447:g6pc3
uniprot id: A0A3P8VCI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glucose-6-phosphatase family.
messages: Endoplasmic reticulum membrane

244447:specc1l
gene id: 244447:specc1l
uniprot id: A0A3P8VNT2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytospin-A family.
messages: Involved in cytokinesis and spindle organization. May play a role in actin cytoskeleton organization and microtubule stabilization and hence required for proper cell adhesion and migration.
messages: May interact with both microtubules and actin cytoskeleton.
messages: cytoskeleton
messages: gap junction
messages: spindle

244447:LOC103381858
gene id: 244447:LOC103381858
uniprot id: A0A3P8WA24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Nucleus

244447:itpka
gene id: 244447:itpka
uniprot id: A0A3P8UKI9
names: Similarity
messages: Belongs to the inositol phosphokinase (IPK) family.

244447:LOC103393235
gene id: 244447:LOC103393235
uniprot id: A0A3P8W4W1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family. Sterol o-acyltransferase subfamily.
messages: Endoplasmic reticulum membrane
messages: Membrane

244447:serpinc1
gene id: 244447:serpinc1
uniprot id: A0A3P8VCR7
names: Similarity
messages: Belongs to the serpin family.

244447:LOC103379972
gene id: 244447:LOC103379972
uniprot id: A0A3P8UN56
names: Subcellular Location Annotation
messages: Membrane

244447:fam72a
gene id: 244447:fam72a
uniprot id: A0A3P8UYS5
names: Similarity
messages: Belongs to the FAM72 family.

244447:kcnk12
gene id: 244447:kcnk12
uniprot id: A0A3P8VYG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

244447:igf1
gene id: 244447:igf1
uniprot id: G4WG38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the insulin family.
messages: Secreted

244447:LOC103398107
gene id: 244447:LOC103398107
uniprot id: A0A3P8VXJ2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase A2 family.
messages: Binds 1 Ca(2+) ion per subunit.
messages: Secreted

244447:LOC103397199
gene id: 244447:LOC103397199
uniprot id: A0A3P8WUR8
uniprot id: A0A3P8X0H1
names: Similarity
messages: Belongs to the G-alpha family. G(q) subfamily.

244447:gda
gene id: 244447:gda
uniprot id: A0A3P8W7T7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia.

244447:trit1
gene id: 244447:trit1
uniprot id: A0A3P8VKL3
names: Function
names: Similarity
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37.

244447:LOC103396059
gene id: 244447:LOC103396059
uniprot id: A0A3P8WEX3
names: Similarity
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

244447:LOC103381476
gene id: 244447:LOC103381476
uniprot id: A0A3P8VH98
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL19 family.
messages: Component of the large ribosomal subunit.

244447:lhfpl5
gene id: 244447:lhfpl5
uniprot id: A0A3P8UHD5
names: Subcellular Location Annotation
messages: Membrane

244447:LOC103384381
gene id: 244447:LOC103384381
uniprot id: A0A3P8WL48
names: Subcellular Location Annotation
messages: Nucleus

244447:igsf11
gene id: 244447:igsf11
uniprot id: A0A3P8V2J7
names: Subcellular Location Annotation
messages: Membrane

244447:slc2a8
gene id: 244447:slc2a8
uniprot id: A0A3P8VIQ9
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

244447:LOC103394749
gene id: 244447:LOC103394749
uniprot id: A0A3P8VVK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type-B carboxylesterase/lipase family.
messages: Cell membrane
messages: Membrane

244447:LOC103395718
gene id: 244447:LOC103395718
uniprot id: A0A3P8WW57
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

244447:LOC103382126
gene id: 244447:LOC103382126
uniprot id: A0A0U1WUU0
names: Similarity
messages: Belongs to the TGF-beta family.

244447:LOC103382275
gene id: 244447:LOC103382275
uniprot id: A0A3P8UKF2
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

244447:LOC103378636
gene id: 244447:LOC103378636
uniprot id: A0A3P8UJ65
names: Subcellular Location Annotation
messages: extracellular space

244447:LOC103385572
gene id: 244447:LOC103385572
uniprot id: A0A3P8X5T9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

244447:nrxn1
gene id: 244447:nrxn1
uniprot id: A0A3P8V6P0
uniprot id: A0A3P8V8U6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neurexin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

244447:shkbp1
gene id: 244447:shkbp1
uniprot id: A0A3P8WFR0
names: Similarity
messages: Belongs to the KCTD3 family.

244447:paqr6
gene id: 244447:paqr6
uniprot id: A0A3P8W764
uniprot id: A0A3P8WCM3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

244447:allc
gene id: 244447:allc
uniprot id: A0A3P8V250
names: Similarity
messages: Belongs to the allantoicase family.

244447:LOC103384621
gene id: 244447:LOC103384621
uniprot id: A0A3P8UQN3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bZIP family.
messages: Homodimer; binds DNA as homodimer. Heterodimer; heterodimerizes with other members of ATF family and with JUN family members.
messages: Nucleus
messages: Stress-responsive chromatin regulator that plays a role in various biological processes including innate immunological memory, adipocyte differentiation or telomerase regulation. In absence of stress, contributes to the formation of heterochromatin and heterochromatin-like structure by recruiting histone H3K9 tri- and di-methyltransferases thus silencing the transcription of target genes such as STAT1 in adipocytes, or genes involved in innate immunity in macrophages and adipocytes. Stress induces ATF7 phosphorylation that disrupts interactions with histone methyltransferase and enhances the association with coactivators containing histone acetyltransferase and/or histone demethylase, leading to disruption of the heterochromatin-like structure and subsequently transcriptional activation. In response to TNF-alpha, which is induced by various stresses, phosphorylated ATF7 and telomerase are released from telomeres leading to telomere shortening.

244447:LOC103380535
gene id: 244447:LOC103380535
uniprot id: A0A3P8WD08
names: Similarity
messages: Belongs to the TEX28 family.

244447:grina
gene id: 244447:grina
uniprot id: A0A3P8WN84
names: Subcellular Location Annotation
messages: Membrane

244447:tbl3
gene id: 244447:tbl3
uniprot id: A0A3P8WIM2
names: Subcellular Location Annotation
messages: nucleolus

244447:nosip
gene id: 244447:nosip
uniprot id: A0A3P8VW41
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOSIP family.
messages: Cytoplasm
messages: Negatively regulates nitric oxide production by inducing nitric oxide synthase translocation to actin cytoskeleton and inhibiting its enzymatic activity.
messages: Nucleus

244447:ttyh2
gene id: 244447:ttyh2
uniprot id: A0A3P8WA90
uniprot id: A0A3P8WAA7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tweety family.
messages: Cell membrane
messages: Membrane
messages: Probable chloride channel.

244447:corin
gene id: 244447:corin
uniprot id: A0A3P8V705
names: Caution
names: Subcellular Location Annotation
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

244447:sod2
gene id: 244447:sod2
uniprot id: A0A3P8UDW4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.
messages: Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.
messages: Homotetramer.
messages: Mitochondrion matrix

244447:wdfy2
gene id: 244447:wdfy2
uniprot id: A0A3P8V9K6
names: Subcellular Location Annotation
messages: Early endosome
messages: Endosome

244447:sumf2
gene id: 244447:sumf2
uniprot id: A0A3P8WQ66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfatase-modifying factor family.
messages: Endoplasmic reticulum lumen

244447:LOC103381986
gene id: 244447:LOC103381986
uniprot id: A0A3P8WVT9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the V-ATPase proteolipid subunit family.
messages: Membrane
messages: Proton-conducting pore forming of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex. The V1 complex consists of three catalytic AB heterodimers that form a heterohexamer, three peripheral stalks each consisting of EG heterodimers, one central rotor including subunits D and F, and the regulatory subunits C and H. The proton translocation complex V0 consists of the proton transport subunit a, a ring of proteolipid subunits c9c'', rotary subunit d, subunits e and f, and the accessory subunits.
messages: Vacuole membrane
messages: clathrin-coated vesicle membrane
messages: synaptic vesicle membrane

244447:LOC103397875
gene id: 244447:LOC103397875
uniprot id: C9WPT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-1 family.
messages: Lysosome
messages: cytosol
messages: extracellular exosome

244447:ampd2
gene id: 244447:ampd2
uniprot id: A0A3P8UP26
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.

244447:bbox1
gene id: 244447:bbox1
uniprot id: A0A3P8UV52
names: Similarity
messages: Belongs to the gamma-BBH/TMLD family.

244447:sgcb
gene id: 244447:sgcb
uniprot id: A0A3P8WYB5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sarcoglycan beta/delta/gamma/zeta family.
messages: Component of the sarcoglycan complex, a subcomplex of the dystrophin-glycoprotein complex which forms a link between the F-actin cytoskeleton and the extracellular matrix.
messages: Cross-link to form 2 major subcomplexes: one consisting of SGCB, SGCD and SGCG and the other consisting of SGCB and SGCD. The association between SGCB and SGCG is particularly strong while SGCA is loosely associated with the other sarcoglycans.
messages: cytoskeleton
messages: sarcolemma

244447:LOC103392741
gene id: 244447:LOC103392741
uniprot id: A0A3P8VM06
names: Similarity
messages: Belongs to the small GTPase superfamily. Arf family.

244447:LOC103397093
gene id: 244447:LOC103397093
uniprot id: A0A3P8W0T4
names: Subcellular Location Annotation
messages: nucleoplasm

244447:LOC103378028
gene id: 244447:LOC103378028
uniprot id: A0A3P8UN74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the akirin family.
messages: Nucleus

244447:emc6
gene id: 244447:emc6
uniprot id: A0A3P8WI80
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EMC6 family.
messages: Component of the ER membrane protein complex (EMC).
messages: Endoplasmic reticulum membrane
messages: Membrane

244447:pfdn2
gene id: 244447:pfdn2
uniprot id: A0A3P8UJW4
names: Function
names: Similarity
messages: Belongs to the prefoldin subunit beta family.
messages: Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins.

244447:cstf1
gene id: 244447:cstf1
uniprot id: A0A3P8W5R7
names: Subcellular Location Annotation
messages: Nucleus

244447:castor2
gene id: 244447:castor2
uniprot id: A0A3P8W905
names: Similarity
messages: Belongs to the GATS family.

244447:LOC103380054
gene id: 244447:LOC103380054
uniprot id: A0A3P8UXV9
uniprot id: A0A3P8UZE4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

244447:mrto4
gene id: 244447:mrto4
uniprot id: A0A3P8X241
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with the pre-60S ribosomal particle.
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Component of the ribosome assembly machinery. Nuclear paralog of the ribosomal protein P0, it binds pre-60S subunits at an early stage of assembly in the nucleolus, and is replaced by P0 in cytoplasmic pre-60S subunits and mature 80S ribosomes.
messages: Cytoplasm
messages: nucleolus

244447:pnmt
gene id: 244447:pnmt
uniprot id: A0A3P8VCH8
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. NNMT/PNMT/TEMT family.

244447:mtnr1a
gene id: 244447:mtnr1a
uniprot id: A0A3P8WH39
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: High affinity receptor for melatonin. The activity of this receptor is mediated by pertussis toxin sensitive G proteins that inhibits adenylate cyclase activity.
messages: Membrane

244447:elp5
gene id: 244447:elp5
uniprot id: A0A3P8UPZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELP5 family.
messages: Cytoplasm
messages: Nucleus

244447:LOC103395724
gene id: 244447:LOC103395724
uniprot id: A0A3P8VPS1
names: Subcellular Location Annotation
messages: Membrane

244447:dmap1
gene id: 244447:dmap1
uniprot id: A0A3P8WA42
names: Subcellular Location Annotation
messages: Nucleus

244447:pts
gene id: 244447:pts
uniprot id: A0A3P8UX64
names: Function
names: Similarity
messages: Belongs to the PTPS family.
messages: Involved in the biosynthesis of tetrahydrobiopterin, an essential cofactor of aromatic amino acid hydroxylases. Catalyzes the transformation of 7,8-dihydroneopterin triphosphate into 6-pyruvoyl tetrahydropterin.

244447:LOC103384488
gene id: 244447:LOC103384488
uniprot id: A0A3P8WZV8
names: Similarity
messages: Belongs to the Gfo/Idh/MocA family.

244447:fam198a
gene id: 244447:fam198a
uniprot id: A0A3P8VWC0
names: Similarity
messages: Belongs to the GASK family.

244447:LOC103384304
gene id: 244447:LOC103384304
uniprot id: A0A3P8WDT3
names: Similarity
messages: Belongs to the syntaxin family.

244447:LOC103388612
gene id: 244447:LOC103388612
uniprot id: A0A3P8VJH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 47 family.
messages: Endoplasmic reticulum membrane

244447:LOC103389793
gene id: 244447:LOC103389793
uniprot id: A0A3P8V3A1
uniprot id: A0A3P8V756
uniprot id: A0A3P8V9F9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAGUK family.
messages: Membrane

244447:bet1
gene id: 244447:bet1
uniprot id: A0A3P8VXH4
names: Subcellular Location Annotation
messages: Membrane

244447:ifi30
gene id: 244447:ifi30
uniprot id: A0A3P8WEE0
names: Similarity
names: Subunit
messages: Belongs to the GILT family.
messages: Dimer; disulfide-linked.

244447:cops7a
gene id: 244447:cops7a
uniprot id: A0A3P8WVP0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSN7/EIF3M family. CSN7 subfamily.
messages: Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53, JUN, I-kappa-B-alpha/NFKBIA, ITPK1 and IRF8/ICSBP, possibly via its association with CK2 and PKD kinases. CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, respectively.
messages: Cytoplasm
messages: Nucleus

244447:rnf43
gene id: 244447:rnf43
uniprot id: A0A3P8VNV4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZNRF3 family.
messages: Cell membrane

244447:lhx6
gene id: 244447:lhx6
uniprot id: A0A3P8WM39
names: Subcellular Location Annotation
messages: Nucleus

244447:LOC103388472
gene id: 244447:LOC103388472
uniprot id: A0A3P8V242
names: Similarity
messages: Belongs to the zygin family.

244447:hoxc6
gene id: 244447:hoxc6
uniprot id: A0A3P8VAI1
names: Subcellular Location Annotation
messages: Nucleus

244447:LOC103384390
gene id: 244447:LOC103384390
uniprot id: A0A3P8WNK7
names: Subcellular Location Annotation
messages: Membrane

244447:ccdc124
gene id: 244447:ccdc124
uniprot id: A0A3P8WP05
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CCDC124 family.
messages: Interacts with RASGEF1B.
messages: Required for proper progression of late cytokinetic stages.

244447:dcaf11
gene id: 244447:dcaf11
uniprot id: A0A3P8VLG0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the WD repeat LEC14B family.
messages: Interacts with DDB1 and CUL4A.
messages: May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex.

244447:ankrd34a
gene id: 244447:ankrd34a
uniprot id: A0A3P8WYM8
names: Similarity
messages: Belongs to the ANKRD34 family.

244447:snx8
gene id: 244447:snx8
uniprot id: A0A3P8X586
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Membrane

244447:tbxa2r
gene id: 244447:tbxa2r
uniprot id: A0A3P8WEG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

244447:ptpre
gene id: 244447:ptpre
uniprot id: A0A3P8VJG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Receptor class 4 subfamily.
messages: Cell membrane
messages: Membrane

244447:LOC103377934
gene id: 244447:LOC103377934
uniprot id: A0A3P8V3W7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC35F solute transporter family.
messages: Membrane

244447:dao
gene id: 244447:dao
uniprot id: A0A3P8VAD8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DAMOX/DASOX family.
messages: Peroxisome

244447:LOC103395087
gene id: 244447:LOC103395087
uniprot id: A0A3P8VNW0
names: Subcellular Location Annotation
messages: focal adhesion
messages: lamellipodium
messages: sarcomere

244447:foxo1
gene id: 244447:foxo1
uniprot id: A0A3P8VPV7
names: Subcellular Location Annotation
messages: Nucleus

244447:mcrip1
gene id: 244447:mcrip1
uniprot id: A0A3P8WMZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCRIP family.
messages: Nucleus
messages: Stress granule

244447:dusp7
gene id: 244447:dusp7
uniprot id: A0A3P8VRR9
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.

244447:prkar1b
gene id: 244447:prkar1b
uniprot id: A0A3P8W3D8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cAMP-dependent kinase regulatory chain family.
messages: Cell membrane
messages: Membrane

244447:LOC103395475
gene id: 244447:LOC103395475
uniprot id: A0A3P8WQ11
names: Similarity
messages: Belongs to the MAP7 family.

244447:utp18
gene id: 244447:utp18
uniprot id: A0A3P8VJ21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat UTP18 family.
messages: nucleolus

244447:pdcd5
gene id: 244447:pdcd5
uniprot id: A0A3P8VF62
names: Similarity
messages: Belongs to the PDCD5 family.

244447:LOC103386498
gene id: 244447:LOC103386498
uniprot id: A0A3P8UFG5
names: Similarity
messages: Belongs to the actin family.

244447:tmem70
gene id: 244447:tmem70
uniprot id: A0A3P8WQ64
names: Similarity
messages: Belongs to the TMEM70 family.

244447:LOC103388282
gene id: 244447:LOC103388282
uniprot id: A0A3P8UL98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CELF/BRUNOL family.
messages: Cytoplasm
messages: Nucleus

244447:sparc
gene id: 244447:sparc
uniprot id: A0A3P8VXM6
names: Similarity
messages: Belongs to the SPARC family.

244447:tp53i3
gene id: 244447:tp53i3
uniprot id: A0A3P8UZ26
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.

244447:LOC103388205
gene id: 244447:LOC103388205
uniprot id: A0A3P8UKW4
names: Similarity
messages: Belongs to the mesothelin family.

244447:eif2b1
gene id: 244447:eif2b1
uniprot id: A0A3P8VUR5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eIF-2B alpha/beta/delta subunits family.
messages: Catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP.
messages: Complex of five different subunits; alpha, beta, gamma, delta and epsilon.

244447:atp13a2
gene id: 244447:atp13a2
uniprot id: A0A3P8UZ87
uniprot id: A0A3P8V5H6
names: Similarity
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily.

244447:cdadc1
gene id: 244447:cdadc1
uniprot id: A0A3P8US87
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

244447:LOC103389349
gene id: 244447:LOC103389349
uniprot id: A0A3P8UQH8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the stanniocalcin family.
messages: Homodimer; disulfide-linked.
messages: Its primary function is the prevention of hypercalcemia. Upon release into the circulation, it lowers calcium transport by the gills, thereby reducing its rate of influx from the environment into the extracellular compartment. STC also stimulates phosphate reabsorption by renal proximal tubules. The consequence of this action is increased levels of plasma phosphate, which combines with excess calcium and promotes its disposal into bone and scales.

244447:LOC103396928
gene id: 244447:LOC103396928
uniprot id: A0A3P8VEU4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic/archaeal RNase P protein component 2 family.
messages: Component of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.
messages: nucleolus

244447:LOC103378776
gene id: 244447:LOC103378776
uniprot id: A0A3P8URT1
uniprot id: A0A3P8UT58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anoctamin family.
messages: Membrane

244447:csnk1e
gene id: 244447:csnk1e
uniprot id: A0A3P8V8F3
names: Similarity
messages: Belongs to the protein kinase superfamily.

244447:LOC103391256
gene id: 244447:LOC103391256
uniprot id: A0A3P8WF87
names: Similarity
messages: Belongs to the synuclein family.

244447:nme3
gene id: 244447:nme3
uniprot id: A0A3P8WPR4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Major role in the synthesis of nucleoside triphosphates other than ATP.
messages: Nucleus
messages: lamellipodium
messages: ruffle

244447:lyg
gene id: 244447:lyg
uniprot id: H8YU86
names: Similarity
messages: Belongs to the glycosyl hydrolase 23 family.

244447:ntn4
gene id: 244447:ntn4
uniprot id: A0A3P8UYE3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

244447:cdh22
gene id: 244447:cdh22
uniprot id: A0A3P8WTJ3
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane
messages: Membrane

244447:usp20
gene id: 244447:usp20
uniprot id: A0A3P8WGG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C19 family. USP20/USP33 subfamily.
messages: centrosome
messages: perinuclear region

244447:pde7b
gene id: 244447:pde7b
uniprot id: A0A3P8UQW7
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

244447:fev
gene id: 244447:fev
uniprot id: A0A3P8WYZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

244447:LOC103397594
gene id: 244447:LOC103397594
uniprot id: A0A3P8WK07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMC family.
messages: Membrane

244447:map2k5
gene id: 244447:map2k5
uniprot id: A0A3P8VZF6
names: Similarity
messages: Belongs to the protein kinase superfamily.

244447:ei24
gene id: 244447:ei24
uniprot id: A0A3P8W146
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EI24 family.
messages: Membrane

244447:LOC103397893
gene id: 244447:LOC103397893
uniprot id: A0A3P8V7I9
names: Similarity
messages: Belongs to the protein prenyltransferase subunit beta family.

244447:cblb
gene id: 244447:cblb
uniprot id: A0A3P8WQF7
names: Domain
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: E3 ubiquitin-protein ligase which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, and transfers it to substrates, generally promoting their degradation by the proteasome.
messages: The N-terminus is composed of the phosphotyrosine binding (PTB) domain, a short linker region and the RING-type zinc finger. The PTB domain, which is also called TKB (tyrosine kinase binding) domain, is composed of three different subdomains: a four-helix bundle (4H), a calcium-binding EF hand and a divergent SH2 domain.

244447:LOC103388428
gene id: 244447:LOC103388428
uniprot id: A0A3P8UW53
names: Subcellular Location Annotation
messages: Nucleus

244447:LOC103387173
gene id: 244447:LOC103387173
uniprot id: A0A3P8UWB4
names: Similarity
messages: Belongs to the cytochrome P450 family.

244447:LOC103377848
gene id: 244447:LOC103377848
uniprot id: A0A3P8UNW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

244447:notum
gene id: 244447:notum
uniprot id: A0A3P8VQY2
names: Similarity
messages: Belongs to the pectinacetylesterase family. Notum subfamily.

244447:ruvbl1
gene id: 244447:ruvbl1
uniprot id: A0A3P8US83
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RuvB family.
messages: Dynein axonemal particle
messages: Nucleus
messages: Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding.

244447:LOC103385437
gene id: 244447:LOC103385437
uniprot id: A0A3P8WXJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Mitochondrion inner membrane

244447:ttc27
gene id: 244447:ttc27
uniprot id: A0A3P8WHE4
names: Similarity
messages: Belongs to the TTC27 family.

244447:cldn19
gene id: 244447:cldn19
uniprot id: A0A3P8WMY2
uniprot id: A0A3P8WNM4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

244447:abl2
gene id: 244447:abl2
uniprot id: A0A3P8W2B8
uniprot id: A0A3P8W2F2
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

244447:rffl
gene id: 244447:rffl
uniprot id: A0A3P8WD09
names: Subcellular Location Annotation
messages: Cell membrane

244447:zhx2
gene id: 244447:zhx2
uniprot id: A0A3P8VX73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZHX family.
messages: Nucleus

244447:LOC103389594
gene id: 244447:LOC103389594
uniprot id: A0A3P8VB45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

244447:LOC103392788
gene id: 244447:LOC103392788
uniprot id: A0A3P8VQF1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Might be involved in growth regulation, and in myelinization in the peripheral nervous system.

244447:LOC103384387
gene id: 244447:LOC103384387
uniprot id: A0A3P8WMU2
names: Similarity
messages: Belongs to the UXT family.

244447:wnt1
gene id: 244447:wnt1
uniprot id: A0A3P8V9R5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

244447:LOC103391015
gene id: 244447:LOC103391015
uniprot id: A0A3P8VUX3
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

244447:gdpd2
gene id: 244447:gdpd2
uniprot id: A0A3P8UWQ7
names: Similarity
messages: Belongs to the glycerophosphoryl diester phosphodiesterase family.

244447:LOC103397836
gene id: 244447:LOC103397836
uniprot id: A0A3P8V5Z5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LRRC8 family.
messages: Cell membrane
messages: Membrane

244447:sgpl1
gene id: 244447:sgpl1
uniprot id: A0A3P8VUH8
names: Similarity
messages: Belongs to the group II decarboxylase family.

244447:otop2
gene id: 244447:otop2
uniprot id: A0A3P8VRT7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the otopetrin family.
messages: Cell membrane
messages: Membrane

244447:LOC103388086
gene id: 244447:LOC103388086
uniprot id: A0A3P8UD32
names: Subcellular Location Annotation
messages: Membrane

244447:fam3c
gene id: 244447:fam3c
uniprot id: A0A3P8V5Q8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM3 family.
messages: Secreted

244447:pipox
gene id: 244447:pipox
uniprot id: A0A3P8V3M5
names: Similarity
messages: Belongs to the MSOX/MTOX family.

244447:LOC103380705
gene id: 244447:LOC103380705
uniprot id: A0A3P8WUS9
names: Similarity
messages: Belongs to the cytochrome P450 family.

244447:LOC103391039
gene id: 244447:LOC103391039
uniprot id: A0A3P8W242
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

244447:LOC103398146
gene id: 244447:LOC103398146
uniprot id: A0A3P8VUU8
names: Similarity
messages: Belongs to the FAM219 family.

244447:ddx51
gene id: 244447:ddx51
uniprot id: A0A3P8WK03
names: Similarity
messages: Belongs to the DEAD box helicase family.

244447:lgmn
gene id: 244447:lgmn
uniprot id: A0A3P8VDW7
names: Similarity
messages: Belongs to the peptidase C13 family.

244447:LOC103393600
gene id: 244447:LOC103393600
uniprot id: A0A3P8W339
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Heterodimer; with an rxr molecule. Binds DNA preferentially as a rar/rxr heterodimer.
messages: Nucleus

244447:dmbx1
gene id: 244447:dmbx1
uniprot id: A0A3P8VUF1
names: Subcellular Location Annotation
messages: Nucleus

244447:mrps15
gene id: 244447:mrps15
uniprot id: A0A3P8WQB6
names: Similarity
messages: Belongs to the universal ribosomal protein uS15 family.

244447:LOC107989993
gene id: 244447:LOC107989993
uniprot id: A0A0Y0G6Q3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FARP (FMRFamide related peptide) family.
messages: Secreted

244447:LOC103381659
gene id: 244447:LOC103381659
uniprot id: A0A3P8VSC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transcription factor STAT family.
messages: Cytoplasm
messages: Nucleus

244447:lgi1
gene id: 244447:lgi1
uniprot id: A0A3P8VCJ8
names: Subcellular Location Annotation
messages: Secreted

244447:klhl15
gene id: 244447:klhl15
uniprot id: A0A3P8WAC2
uniprot id: A0A3P8WIF9
names: Subcellular Location Annotation
messages: Nucleus

244447:tmem192
gene id: 244447:tmem192
uniprot id: A0A3P8V038
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM192 family.
messages: Late endosome
messages: Lysosome membrane
messages: Membrane

244447:pik3cb
gene id: 244447:pik3cb
uniprot id: A0A3P8VZT4
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.

244447:cd36
gene id: 244447:cd36
uniprot id: A0A3P8V7L8
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the CD36 family.
messages: Cell membrane
messages: Golgi apparatus
messages: Membrane
messages: Membrane raft

244447:LOC103395315
gene id: 244447:LOC103395315
uniprot id: A0A3P8WCQ7
uniprot id: A0A3P8WCR2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

244447:LOC107989480
gene id: 244447:LOC107989480
uniprot id: A0A3P8VKQ5
names: Caution
names: Function
names: Subunit
messages: Heterodimer of a light chain and a heavy chain linked by a disulfide bond.
messages: Initiates the extrinsic pathway of blood coagulation. Serine protease that circulates in the blood in a zymogen form. Factor VII is converted to factor VIIa by factor Xa, factor XIIa, factor IXa, or thrombin by minor proteolysis. In the presence of tissue factor and calcium ions, factor VIIa then converts factor X to factor Xa by limited proteolysis. Factor VIIa will also convert factor IX to factor IXa in the presence of tissue factor and calcium.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

244447:LOC103397790
gene id: 244447:LOC103397790
uniprot id: A0A3P8WSJ5
names: Similarity
messages: Belongs to the peptidase M17 family.

244447:sh3bgrl
gene id: 244447:sh3bgrl
uniprot id: A0A3P8WPK5
names: Similarity
messages: Belongs to the SH3BGR family.

244447:LOC103388738
gene id: 244447:LOC103388738
uniprot id: A0A3P8VMC4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

244447:aoc1
gene id: 244447:aoc1
uniprot id: A0A3P8V8I8
uniprot id: A0A3P8VB53
names: Cofactor
names: PTM
names: Similarity
messages: Belongs to the copper/topaquinone oxidase family.
messages: Contains 1 topaquinone per subunit.
messages: Topaquinone (TPQ) is generated by copper-dependent autoxidation of a specific tyrosyl residue.

244447:slc1a2
gene id: 244447:slc1a2
uniprot id: A0A3P8W472
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

244447:LOC103378799
gene id: 244447:LOC103378799
uniprot id: A0A3P8UV46
names: Subcellular Location Annotation
messages: Membrane

244447:fam83c
gene id: 244447:fam83c
uniprot id: A0A3P8WM99
names: Similarity
messages: Belongs to the FAM83 family.

244447:fam69c
gene id: 244447:fam69c
uniprot id: A0A3P8WLZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DIPK family.
messages: Endoplasmic reticulum membrane

244447:rrp12
gene id: 244447:rrp12
uniprot id: A0A3P8VI71
names: Similarity
messages: Belongs to the RRP12 family.

244447:LOC103384023
gene id: 244447:LOC103384023
uniprot id: A0A3P8VPE1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEC23/SEC24 family. SEC23 subfamily.
messages: COPII-coated vesicle membrane
messages: Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: cytosol

244447:LOC103397973
gene id: 244447:LOC103397973
uniprot id: A0A3P8VJY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SURF4 family.
messages: Membrane

244447:pik3ca
gene id: 244447:pik3ca
uniprot id: A0A3P8X0H3
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.

244447:asip
gene id: 244447:asip
uniprot id: A0A3P8WY79
names: Subcellular Location Annotation
messages: Secreted

244447:LOC103397984
gene id: 244447:LOC103397984
uniprot id: A0A3P8VLK6
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

244447:rpa2
gene id: 244447:rpa2
uniprot id: A0A3P8WQT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the replication factor A protein 2 family.
messages: Nucleus

244447:dctn2
gene id: 244447:dctn2
uniprot id: A0A3P8VR09
names: Function
names: Similarity
messages: Belongs to the dynactin subunit 2 family.
messages: Modulates cytoplasmic dynein binding to an organelle, and plays a role in prometaphase chromosome alignment and spindle organization during mitosis. Involved in anchoring microtubules to centrosomes. May play a role in synapse formation during brain development.

244447:hspb8
gene id: 244447:hspb8
uniprot id: A0A3P8X0U7
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

244447:cpn1
gene id: 244447:cpn1
uniprot id: A0A3P8VAP1
names: Similarity
messages: Belongs to the peptidase M14 family.

244447:slc6a17
gene id: 244447:slc6a17
uniprot id: A0A3P8UWV3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

244447:LOC103398270
gene id: 244447:LOC103398270
uniprot id: A0A3P8WBG1
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. cGMP subfamily.

244447:isyna1
gene id: 244447:isyna1
uniprot id: A0A3P8V4S2
names: Similarity
messages: Belongs to the myo-inositol 1-phosphate synthase family.

244447:LOC103394972
gene id: 244447:LOC103394972
uniprot id: A0A3P8WLS2
names: Subcellular Location Annotation
messages: Membrane

244447:tm2d3
gene id: 244447:tm2d3
uniprot id: A0A3P8VQD0
names: Subcellular Location Annotation
messages: Membrane

244447:mpv17l2
gene id: 244447:mpv17l2
uniprot id: A0A3P8WER7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxisomal membrane protein PXMP2/4 family.
messages: Membrane

244447:LOC103390810
gene id: 244447:LOC103390810
uniprot id: A0A3P8V5U2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Endosome membrane
messages: Membrane

244447:vkorc1l1
gene id: 244447:vkorc1l1
uniprot id: A0A3P8WLA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VKOR family.
messages: Endoplasmic reticulum membrane
messages: Membrane

244447:prpf4
gene id: 244447:prpf4
uniprot id: A0A3P8WZ87
names: Subcellular Location Annotation
messages: Nucleus speckle

244447:lrrn1
gene id: 244447:lrrn1
uniprot id: A0A3P8UV53
names: Subcellular Location Annotation
messages: Membrane

244447:pld5
gene id: 244447:pld5
uniprot id: A0A3P8VSX1
names: Similarity
messages: Belongs to the phospholipase D family.

244447:LOC103380712
gene id: 244447:LOC103380712
uniprot id: A0A3P8WRX3
names: Subcellular Location Annotation
messages: Nucleus

244447:mtmr10
gene id: 244447:mtmr10
uniprot id: A0A3P8UJF5
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.

244447:serinc1
gene id: 244447:serinc1
uniprot id: A0A3P8WH50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TDE1 family.
messages: Membrane

244447:LOC103395228
gene id: 244447:LOC103395228
uniprot id: A0A3P8VYQ0
uniprot id: A0A3P8W1E4
names: Subcellular Location Annotation
messages: Cytoplasm

244447:ppme1
gene id: 244447:ppme1
uniprot id: A0A3P8WCG4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the AB hydrolase superfamily.
messages: Binds PPP2CA and PPP2CB.
messages: Demethylates proteins that have been reversibly carboxymethylated. Demethylates PPP2CB (in vitro) and PPP2CA. Binding to PPP2CA displaces the manganese ion and inactivates the enzyme.

244447:LOC103397570
gene id: 244447:LOC103397570
uniprot id: A0A3P8WFC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

244447:LOC103398354
gene id: 244447:LOC103398354
uniprot id: A0A3P8UFC6
names: Similarity
messages: Belongs to the serpin family. Ov-serpin subfamily.

244447:agpat4
gene id: 244447:agpat4
uniprot id: A0A3P8V410
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

244447:LOC103394978
gene id: 244447:LOC103394978
uniprot id: A0A3P8WSS6
names: Subcellular Location Annotation
messages: Nucleus

244447:LOC103396190
gene id: 244447:LOC103396190
uniprot id: A0A3P8WVD8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complement C6/C7/C8/C9 family.
messages: Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

244447:tysnd1
gene id: 244447:tysnd1
uniprot id: A0A3P8V2Y7
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1B family.
messages: Peroxisomal protease that mediates both the removal of the leader peptide from proteins containing a PTS2 target sequence and processes several PTS1-containing proteins. Catalyzes the processing of PTS1-proteins involved in the peroxisomal beta-oxidation of fatty acids.
messages: Peroxisome
messages: The full-lengh TYSND1 is the active the proteolytic processing of PTS1- and PTS2-proteins and in self-cleavage, and intermolecular self-cleavage of TYSND1 down-regulates its protease activity.

244447:nipal3
gene id: 244447:nipal3
uniprot id: A0A3P8ULS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NIPA family.
messages: Membrane

244447:prss16
gene id: 244447:prss16
uniprot id: A0A3P8V5J4
names: Similarity
messages: Belongs to the peptidase S28 family.

244447:LOC107990263
gene id: 244447:LOC107990263
uniprot id: A0A3P8WCT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta-microseminoprotein family.
messages: Secreted

244447:slc25a40
gene id: 244447:slc25a40
uniprot id: A0A3P8UPV0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

244447:nkiras2
gene id: 244447:nkiras2
uniprot id: A0A3P8WLU7
names: Similarity
messages: Belongs to the small GTPase superfamily. Ras family. KappaB-Ras subfamily.

244447:pax6
gene id: 244447:pax6
uniprot id: A0A3P8WD93
uniprot id: A0A3P8WDA4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paired homeobox family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

244447:LOC103380557
gene id: 244447:LOC103380557
uniprot id: A0A3P8WAY6
names: Similarity
messages: Belongs to the LEM family.

244447:hapln4
gene id: 244447:hapln4
uniprot id: A0A3P8VDV8
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

244447:arhgap26
gene id: 244447:arhgap26
uniprot id: A0A3P8VWT1
names: Subcellular Location Annotation
messages: cytoskeleton
messages: focal adhesion

244447:LOC103392009
gene id: 244447:LOC103392009
uniprot id: A0A3P8VKN9
names: Similarity
messages: Belongs to the WD repeat EBI family.

244447:ehhadh
gene id: 244447:ehhadh
uniprot id: A0A3P8W158
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.

244447:LOC103394667
gene id: 244447:LOC103394667
uniprot id: A0A3P8VHS4
uniprot id: A0A3P8VKP5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CYRI family.
messages: Membrane

244447:LOC103396559
gene id: 244447:LOC103396559
uniprot id: A0A3P8WSA8
names: Similarity
messages: Belongs to the Niban family.

244447:LOC103393429
gene id: 244447:LOC103393429
uniprot id: A0A3P8W8S4
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lysyl oxidase family.
messages: Contains 1 lysine tyrosylquinone.
messages: Mediates the post-translational oxidative deamination of lysine residues on target proteins leading to the formation of deaminated lysine (allysine).
messages: The lysine tyrosylquinone cross-link (LTQ) is generated by condensation of the epsilon-amino group of a lysine with a topaquinone produced by oxidation of tyrosine.
messages: extracellular space

244447:LOC103389010
gene id: 244447:LOC103389010
uniprot id: A0A3P8WAD1
names: Similarity
messages: Belongs to the apolipoprotein A1/A4/E family.

244447:LOC103396414
gene id: 244447:LOC103396414
uniprot id: A0A3P8W0T3
names: Similarity
messages: Belongs to the SNF7 family.

244447:LOC103381556
gene id: 244447:LOC103381556
uniprot id: A0A3P8VS52
names: Caution
names: Similarity
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

244447:iah1
gene id: 244447:iah1
uniprot id: A0A3P8UP28
names: Function
names: Similarity
messages: Belongs to the 'GDSL' lipolytic enzyme family. IAH1 subfamily.
messages: Probable lipase.

244447:LOC103395050
gene id: 244447:LOC103395050
uniprot id: A0A1D8QQG5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

244447:gtf2e1
gene id: 244447:gtf2e1
uniprot id: A0A3P8WFY6
names: Similarity
messages: Belongs to the TFIIE alpha subunit family.

244447:iscu
gene id: 244447:iscu
uniprot id: A0A3P8WDZ8
names: Function
names: Similarity
messages: Belongs to the NifU family.
messages: Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins.

244447:LOC103386292
gene id: 244447:LOC103386292
uniprot id: A0A3P8UJN7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel (TC 2.A.49) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

244447:LOC103380135
gene id: 244447:LOC103380135
uniprot id: A0A3P8V240
names: Similarity
messages: Belongs to the bZIP family. Maf subfamily.

244447:cmc1
gene id: 244447:cmc1
uniprot id: A0A3P8VMG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CMC family.
messages: Mitochondrion

244447:endou
gene id: 244447:endou
uniprot id: A0A3P8UPY2
names: Similarity
names: Subunit
messages: Belongs to the ENDOU family.
messages: Monomer.

244447:LOC103394273
gene id: 244447:LOC103394273
uniprot id: A0A3P8WGM6
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

244447:LOC103384461
gene id: 244447:LOC103384461
uniprot id: A0A3P8WRL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane

244447:LOC103393953
gene id: 244447:LOC103393953
uniprot id: A0A3P8VM29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 'GDXG' lipolytic enzyme family.
messages: Cell membrane
messages: Lipid droplet
messages: caveola
messages: cytosol

244447:sh3bgrl3
gene id: 244447:sh3bgrl3
uniprot id: A0A3P8VN49
names: Similarity
messages: Belongs to the SH3BGR family.

244447:LOC103391191
gene id: 244447:LOC103391191
uniprot id: A0A3P8WF97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family.
messages: Belongs to the acetate uptake transporter (AceTr) (TC 2.A.96) family.
messages: Membrane

244447:LOC103391539
gene id: 244447:LOC103391539
uniprot id: A0A3P8X0M8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

244447:LOC103396322
gene id: 244447:LOC103396322
uniprot id: A0A3P8VSJ1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

244447:vamp3
gene id: 244447:vamp3
uniprot id: A0A3P8UZE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Membrane

244447:LOC103382001
gene id: 244447:LOC103382001
uniprot id: A0A3P8WTV0
uniprot id: A0A3P8WTV8
uniprot id: A0A3P8WXT0
names: Subcellular Location Annotation
messages: Membrane

244447:LOC103378323
gene id: 244447:LOC103378323
uniprot id: A0A3P8WBT5
uniprot id: A0A3P8WE62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nectin family.
messages: Membrane

244447:hoxc8
gene id: 244447:hoxc8
uniprot id: A0A3P8VD63
names: Subcellular Location Annotation
messages: Nucleus

244447:LOC103383933
gene id: 244447:LOC103383933
uniprot id: A0A3P8VHH2
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lysyl oxidase family.
messages: Contains 1 lysine tyrosylquinone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mediates the post-translational oxidative deamination of lysine residues on target proteins leading to the formation of deaminated lysine (allysine).
messages: The lysine tyrosylquinone cross-link (LTQ) is generated by condensation of the epsilon-amino group of a lysine with a topaquinone produced by oxidation of tyrosine.
messages: extracellular space

244447:LOC103390756
gene id: 244447:LOC103390756
uniprot id: A0A3P8UA99
names: Subcellular Location Annotation
messages: Nucleus

244447:taf6
gene id: 244447:taf6
uniprot id: A0A3P8V9K2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF6 family.
messages: Nucleus

244447:LOC103387811
gene id: 244447:LOC103387811
uniprot id: A0A3P8WTJ0
names: Similarity
messages: Belongs to the pyridoxine kinase family.

244447:LOC103385780
gene id: 244447:LOC103385780
uniprot id: A0A3P8UMN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

244447:hacl1
gene id: 244447:hacl1
uniprot id: A0A3P8V392
names: Similarity
messages: Belongs to the TPP enzyme family.

244447:LOC103393325
gene id: 244447:LOC103393325
uniprot id: A0A3P8V4S9
uniprot id: A0A3P8VAY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. PAR subfamily.
messages: Nucleus

244447:LOC103395435
gene id: 244447:LOC103395435
uniprot id: A0A3P8WU35
uniprot id: A0A3P8WWG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the myelin proteolipid protein family.
messages: Membrane

244447:LOC103381718
gene id: 244447:LOC103381718
uniprot id: A0A3P8VYT5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

244447:slc40a1
gene id: 244447:slc40a1
uniprot id: A0A3P8WHK3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferroportin (FP) (TC 2.A.100) family. SLC40A subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: May be involved in iron transport and iron homeostasis.
messages: Membrane

244447:gtf2h1
gene id: 244447:gtf2h1
uniprot id: A0A3P8V654
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFB1 family.
messages: Nucleus

244447:anapc16
gene id: 244447:anapc16
uniprot id: A0A3P8WGM5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the APC16 family.
messages: Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.
messages: Cytoplasm
messages: Nucleus
messages: kinetochore

244447:gdf11
gene id: 244447:gdf11
uniprot id: A0A3P8V1V2
names: Similarity
messages: Belongs to the TGF-beta family.

244447:dpt
gene id: 244447:dpt
uniprot id: A0A3P8UPN4
names: Similarity
messages: Belongs to the dermatopontin family.

244447:LOC103383788
gene id: 244447:LOC103383788
uniprot id: A0A3P8VHV9
names: Function
names: Similarity
messages: Belongs to the rod/cone cGMP-PDE gamma subunit family.
messages: Participates in processes of transmission and amplification of the visual signal. cGMP-PDEs are the effector molecules in G-protein-mediated phototransduction in vertebrate rods and cones.

244447:prmt5
gene id: 244447:prmt5
uniprot id: A0A3P8X1P0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA).
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily.
messages: Cytoplasm
messages: Nucleus

244447:sema5a
gene id: 244447:sema5a
uniprot id: A0A3P8VMK0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

244447:LOC103392838
gene id: 244447:LOC103392838
uniprot id: A0A3P8VZ30
names: Similarity
messages: Belongs to the pyrroline-5-carboxylate reductase family.

244447:LOC103392730
gene id: 244447:LOC103392730
uniprot id: A0A3P8VPM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Membrane

244447:LOC103389365
gene id: 244447:LOC103389365
uniprot id: A0A3P8UJA6
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

244447:prdx5
gene id: 244447:prdx5
uniprot id: A0A3P8VNR2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxiredoxin family. Prx5 subfamily.
messages: Peroxisome matrix
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides and as sensor of hydrogen peroxide-mediated signaling events.

244447:egfl7
gene id: 244447:egfl7
uniprot id: A0A3P8W4N4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

244447:LOC103379412
gene id: 244447:LOC103379412
uniprot id: A0A3P8VXV0
names: Similarity
messages: Belongs to the BtpA family.

244447:LOC103394994
gene id: 244447:LOC103394994
uniprot id: A0A3P8WP03
names: Similarity
messages: Belongs to the WD repeat coronin family.

244447:usp44
gene id: 244447:usp44
uniprot id: A0A3P8UZV5
names: Similarity
messages: Belongs to the peptidase C19 family.

244447:ss18
gene id: 244447:ss18
uniprot id: A0A3P8VTP3
uniprot id: A0A3P8VZ63
names: Similarity
messages: Belongs to the SS18 family.

244447:LOC103389224
gene id: 244447:LOC103389224
uniprot id: A0A3P8UDA0
names: Subcellular Location Annotation
messages: extracellular matrix

244447:LOC103392887
gene id: 244447:LOC103392887
uniprot id: A0A3P8VYT4
names: Similarity
messages: Belongs to the TECPR1 family.

244447:slc6a4
gene id: 244447:slc6a4
uniprot id: A0A3P8UYG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

244447:LOC103395579
gene id: 244447:LOC103395579
uniprot id: A0A3P8WWG1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 7 family.
messages: Golgi apparatus membrane
messages: Membrane
messages: Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids.

244447:tub
gene id: 244447:tub
uniprot id: A0A3P8VM83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TUB family.
messages: Secreted

244447:LOC103397469
gene id: 244447:LOC103397469
uniprot id: A0A3P8VRC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adaptor complexes medium subunit family.
messages: Cytoplasmic vesicle membrane
messages: Golgi apparatus

244447:slc17a6
gene id: 244447:slc17a6
uniprot id: A0A3P8V5B1
names: Subcellular Location Annotation
messages: Membrane

244447:eed
gene id: 244447:eed
uniprot id: A0A3P8UFP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat ESC family.
messages: Nucleus

244447:LOC103386337
gene id: 244447:LOC103386337
uniprot id: A0A3P8VL64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 2 family.
messages: Golgi apparatus membrane
messages: Membrane

244447:LOC103379930
gene id: 244447:LOC103379930
uniprot id: A0A3P8ULE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
messages: Cleavage furrow
messages: Midbody
messages: cilium axoneme
messages: kinetochore
messages: spindle

244447:dnase2
gene id: 244447:dnase2
uniprot id: A0A3P8W684
names: Similarity
messages: Belongs to the DNase II family.

244447:drd3
gene id: 244447:drd3
uniprot id: A0A3P8WPT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

244447:LOC103396249
gene id: 244447:LOC103396249
uniprot id: A0A3P8WX40
names: Similarity
messages: Belongs to the GORASP family.

244447:LOC103385733
gene id: 244447:LOC103385733
uniprot id: A0A3P8UH94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM3 family.
messages: Secreted

244447:polr2b
gene id: 244447:polr2b
uniprot id: A0A3P8V592
names: Function
names: Similarity
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.

244447:LOC103390621
gene id: 244447:LOC103390621
uniprot id: A0A3P8VBA7
names: Similarity
messages: Belongs to the myozenin family.

244447:LOC103391677
gene id: 244447:LOC103391677
uniprot id: A0A3P8UV77
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.

244447:LOC103393491
gene id: 244447:LOC103393491
uniprot id: A0A3P8VUE7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PPP1R35 family.
messages: centriole

244447:LOC103382086
gene id: 244447:LOC103382086
uniprot id: A0A3P8WTR4
uniprot id: A0A3P8WZI4
names: Subcellular Location Annotation
messages: Membrane

244447:LOC103386667
gene id: 244447:LOC103386667
uniprot id: A0A3P8UI85
names: Subcellular Location Annotation
messages: Membrane

244447:mfn2
gene id: 244447:mfn2
uniprot id: A0A3P8UVL2
names: Subcellular Location Annotation
messages: Membrane
messages: Mitochondrion outer membrane

244447:gatad1
gene id: 244447:gatad1
uniprot id: A0A3P8WR51
names: Subcellular Location Annotation
messages: Nucleus

244447:LOC103384880
gene id: 244447:LOC103384880
uniprot id: A0A3P8UXT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

244447:irf6
gene id: 244447:irf6
uniprot id: A0A3P8UTV5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IRF family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

244447:LOC103384932
gene id: 244447:LOC103384932
uniprot id: A0A3P8V4K3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

244447:LOC103391252
gene id: 244447:LOC103391252
uniprot id: A0A1L6KTK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

244447:slc16a7
gene id: 244447:slc16a7
uniprot id: A0A3P8WD71
names: Similarity
names: Subcellular Location Annotation
messages: Basolateral cell membrane
messages: Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.
messages: Cytoplasm
messages: Membrane

244447:fign
gene id: 244447:fign
uniprot id: A0A3P8VMK1
uniprot id: A0A3P8VSZ8
names: Similarity
messages: Belongs to the AAA ATPase family.

244447:dis3l
gene id: 244447:dis3l
uniprot id: A0A3P8VDE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNR ribonuclease family.
messages: Cytoplasm

244447:ptgir
gene id: 244447:ptgir
uniprot id: A0A3P8VBD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

244447:LOC103384436
gene id: 244447:LOC103384436
uniprot id: A0A3P8WV44
names: Similarity
messages: Belongs to the DNase I family.

244447:cdv3
gene id: 244447:cdv3
uniprot id: A0A3P8X0G1
names: Similarity
messages: Belongs to the CDV3 family.

244447:slitrk3
gene id: 244447:slitrk3
uniprot id: A0A3P8UPH5
names: Similarity
messages: Belongs to the SLITRK family.

244447:sema5b
gene id: 244447:sema5b
uniprot id: A0A3P8V0Q4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

244447:sord
gene id: 244447:sord
uniprot id: A0A3P8US43
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the zinc-containing alcohol dehydrogenase family.
messages: Mitochondrion membrane
messages: flagellum

244447:gabbr2
gene id: 244447:gabbr2
uniprot id: A0A3P8VF48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 3 family. GABA-B receptor subfamily.
messages: Cell membrane
messages: Membrane

244447:LOC103396118
gene id: 244447:LOC103396118
uniprot id: A0A3P8WI65
names: Similarity
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily.

244447:LOC103382138
gene id: 244447:LOC103382138
uniprot id: A0A3P8X2D7
names: Similarity
messages: Belongs to the DeSI family.

244447:ing5
gene id: 244447:ing5
uniprot id: A0A3P8V1H4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ING family.
messages: Component of an histone acetyltransferase complex.
messages: Component of an histone acetyltransferase complex. Interacts with H3K4me3 and to a lesser extent with H3K4me2.
messages: Nucleus
messages: The PHD-type zinc finger mediates the binding to H3K4me3.

244447:LOC103382281
gene id: 244447:LOC103382281
uniprot id: A0A3P8UII5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSG1 family.
messages: Membrane

244447:LOC103384120
gene id: 244447:LOC103384120
uniprot id: A0A3P8VXC0
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

244447:ttll9
gene id: 244447:ttll9
uniprot id: A0A3P8V7Z6
names: Similarity
messages: Belongs to the tubulin--tyrosine ligase family.

244447:LOC103379212
gene id: 244447:LOC103379212
uniprot id: A0A3P8VAP4
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

244447:LOC103386395
gene id: 244447:LOC103386395
uniprot id: A0A3P8UBI1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SCAR/WAVE family.
messages: Binds actin and the Arp2/3 complex.
messages: Downstream effector molecule involved in the transmission of signals from tyrosine kinase receptors and small GTPases to the actin cytoskeleton. Promotes formation of actin filaments. Part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex.
messages: cytoskeleton

244447:rnasek
gene id: 244447:rnasek
uniprot id: A0A3P8VC61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase K family.
messages: Membrane

244447:nfya
gene id: 244447:nfya
uniprot id: A0A3P8UWZ9
uniprot id: A0A3P8UX04
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NFYA/HAP2 subunit family.
messages: Component of the sequence-specific heterotrimeric transcription factor (NF-Y) which specifically recognizes a 5'-CCAAT-3' box motif found in the promoters of its target genes.
messages: Heterotrimer.
messages: Nucleus

244447:LOC103387386
gene id: 244447:LOC103387386
uniprot id: A0A3P8VEY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COX15/CtaA family.
messages: Membrane

244447:LOC103389654
gene id: 244447:LOC103389654
uniprot id: A0A3P8VFM4
names: Similarity
messages: Belongs to the alpha-ketoglutarate dehydrogenase family.

244447:LOC103395391
gene id: 244447:LOC103395391
uniprot id: A0A3P8WHJ4
uniprot id: A0A3P8WMP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM120 family.
messages: Membrane
messages: Nucleus inner membrane

244447:LOC103385783
gene id: 244447:LOC103385783
uniprot id: A0A3P8UMU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptophysin/synaptobrevin family.
messages: Membrane

244447:snrpd3
gene id: 244447:snrpd3
uniprot id: A0A3P8UQM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP core protein family.
messages: Nucleus
messages: cytosol

244447:foxi3
gene id: 244447:foxi3
uniprot id: A0A3P8WGY6
names: Subcellular Location Annotation
messages: Nucleus

244447:polr3k
gene id: 244447:polr3k
uniprot id: A0A3P8VLF7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.
messages: Component of the RNA polymerase III (Pol III) complex consisting of 17 subunits.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: nucleolus

244447:pdia6
gene id: 244447:pdia6
uniprot id: A0A3P8X1D4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein disulfide isomerase family.
messages: Endoplasmic reticulum lumen
messages: Melanosome

244447:LOC103399907
gene id: 244447:LOC103399907
uniprot id: A0A3P8ULK6
names: Subcellular Location Annotation
messages: Nucleus

244447:adamts16
gene id: 244447:adamts16
uniprot id: A0A3P8USB8
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

244447:fam199x
gene id: 244447:fam199x
uniprot id: A0A3P8W231
names: Similarity
messages: Belongs to the FAM199 family.

244447:acly
gene id: 244447:acly
uniprot id: A0A3P8WLJ4
names: Function
names: Similarity
names: Subunit
messages: Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the succinate/malate CoA ligase alpha subunit family.
messages: In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family.

244447:LOC103390929
gene id: 244447:LOC103390929
uniprot id: A0A3P8V7G4
names: Similarity
messages: Belongs to the JAKMIP family.

244447:LOC103391788
gene id: 244447:LOC103391788
uniprot id: A0A3P8UZH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the jagunal family.
messages: Endoplasmic reticulum membrane
messages: Membrane

244447:drd1
gene id: 244447:drd1
uniprot id: A0A3P8W6L3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

244447:trmt5
gene id: 244447:trmt5
uniprot id: A0A3P8UIS2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRM5 / TYW2 family.
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM5/TYW2 family.
messages: Cytoplasm
messages: Mitochondrion matrix
messages: Monomer.
messages: Nucleus
messages: Specifically methylates the N1 position of guanosine-37 in various cytoplasmic and mitochondrial tRNAs. Methylation is not dependent on the nature of the nucleoside 5' of the target nucleoside. This is the first step in the biosynthesis of wybutosine (yW), a modified base adjacent to the anticodon of tRNAs and required for accurate decoding.

244447:tsc22d2
gene id: 244447:tsc22d2
uniprot id: A0A3P8WF61
names: Similarity
messages: Belongs to the TSC-22/Dip/Bun family.

244447:nxt2
gene id: 244447:nxt2
uniprot id: A0A3P8WR83
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Has a role in nuclear-cytoplasmic transport of proteins and mRNAs.
messages: Nucleus

244447:dcaf13
gene id: 244447:dcaf13
uniprot id: A0A3P8W6P6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat DCAF13/WDSOF1 family.
messages: nucleolus

244447:slco3a1
gene id: 244447:slco3a1
uniprot id: A0A3P8UV42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the organo anion transporter (TC 2.A.60) family.
messages: Cell membrane
messages: Membrane

244447:nup62
gene id: 244447:nup62
uniprot id: A0A3P8V7X1
names: Similarity
messages: Belongs to the nucleoporin NSP1/NUP62 family.

244447:LOC103389147
gene id: 244447:LOC103389147
uniprot id: A0A3P8WMP5
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. HMG-CoA synthase family.
messages: Catalyzes the condensation of acetyl-CoA with acetoacetyl-CoA to form HMG-CoA.

244447:LOC103377222
gene id: 244447:LOC103377222
uniprot id: A0A3P8WL51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family.
messages: Cell membrane
messages: Membrane

244447:LOC103389936
gene id: 244447:LOC103389936
uniprot id: A0A3P8V3N6
names: Function
names: Similarity
messages: Belongs to the profilin family.
messages: Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG.

244447:LOC103396286
gene id: 244447:LOC103396286
uniprot id: A0A3P8VTX8
names: Caution
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Binds equally well IGF1 and IGF2.
messages: IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. Promotes cell migration.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

244447:LOC103377433
gene id: 244447:LOC103377433
uniprot id: A0A3P8UCY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calycin superfamily. Lipocalin family.
messages: Secreted

244447:LOC103382562
gene id: 244447:LOC103382562
uniprot id: A0A3P8UXM9
names: Similarity
messages: Belongs to the DNA photolyase class-1 family.

244447:LOC103398190
gene id: 244447:LOC103398190
uniprot id: A0A3P8WCD2
names: Similarity
messages: Belongs to the LIX1 family.

244447:LOC103377456
gene id: 244447:LOC103377456
uniprot id: A0A3P8UI98
names: Similarity
messages: Belongs to the SNF7 family.

244447:LOC103388483
gene id: 244447:LOC103388483
uniprot id: A0A3P8VFL2
names: Similarity
messages: Belongs to the cytochrome P450 family.

244447:LOC103381509
gene id: 244447:LOC103381509
uniprot id: A0A3P8VFR8
names: Function
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
messages: Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues within the same substrate, with a preference for phosphotyrosine as a substrate (By similarity). Involved in the modulation of AMPK and MAPK1/2 signaling pathways.
messages: Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate.

244447:LOC103397486
gene id: 244447:LOC103397486
uniprot id: A0A3P8VIX0
names: Subcellular Location Annotation
messages: Membrane

244447:LOC103396535
gene id: 244447:LOC103396535
uniprot id: A0A3P8WP68
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

244447:LOC103395620
gene id: 244447:LOC103395620
uniprot id: A0A3P8WZY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF9 family.
messages: Nucleus

244447:LOC103384926
gene id: 244447:LOC103384926
uniprot id: A0A3P8V005
names: Subcellular Location Annotation
messages: Membrane

244447:LOC103377294
gene id: 244447:LOC103377294
uniprot id: A0A3P8WNK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAVIN family.
messages: caveola

244447:ncbp1
gene id: 244447:ncbp1
uniprot id: A0A3P8VYN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NCBP1 family.
messages: Nucleus

244447:vps26a
gene id: 244447:vps26a
uniprot id: A0A3P8W8S9
names: Similarity
messages: Belongs to the VPS26 family.

244447:polr3c
gene id: 244447:polr3c
uniprot id: A0A3P8USN0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic RPC3/POLR3C RNA polymerase subunit family.
messages: Component of the RNA polymerase III (Pol III) complex consisting of 17 subunits.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific core component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs.
messages: Nucleus

244447:tjp2
gene id: 244447:tjp2
uniprot id: A0A3P8VHL4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAGUK family.
messages: Cell membrane
messages: Membrane
messages: tight junction

244447:LOC103377124
gene id: 244447:LOC103377124
uniprot id: A0A3P8W695
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.

244447:phospho1
gene id: 244447:phospho1
uniprot id: A0A3P8WNL4
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. PHOSPHO family.

244447:bpnt1
gene id: 244447:bpnt1
uniprot id: A0A3P8USH4
uniprot id: A0A3P8UUU8
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

244447:LOC103390626
gene id: 244447:LOC103390626
uniprot id: A0A3P8UCS2
names: Similarity
messages: Belongs to the KHDRBS family.

244447:LOC103393605
gene id: 244447:LOC103393605
uniprot id: A0A3P8W3A9
names: Subcellular Location Annotation
messages: Nucleus

244447:slc5a6
gene id: 244447:slc5a6
uniprot id: A0A3P8WPW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

244447:LOC103380473
gene id: 244447:LOC103380473
uniprot id: A0A3P8W3Z4
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

244447:LOC103379314
gene id: 244447:LOC103379314
uniprot id: A0A3P8UX92
names: Function
messages: Regulates (in vitro) the inhibition of rhodopsin phosphorylation in a calcium-dependent manner.

244447:LOC103398008
gene id: 244447:LOC103398008
uniprot id: A0A0D3QH52
names: Similarity
messages: Belongs to the PI3K p85 subunit family.

244447:rpl36
gene id: 244447:rpl36
uniprot id: A0A3P8WVN3
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL36 family.

244447:sars2
gene id: 244447:sars2
uniprot id: A0A3P8W9R0
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.

244447:rnf8
gene id: 244447:rnf8
uniprot id: A0A3P8WY87
uniprot id: A0A3P8X3T5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CHFR family.
messages: Belongs to the RNF8 family.
messages: E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites. Following DNA DSBs, it is recruited to the sites of damage by ATM-phosphorylated MDC1 and catalyzes the 'Lys-63'-linked ubiquitination of histones H2A and H2AX, thereby promoting the formation of TP53BP1 and BRCA1 ionizing radiation-induced foci (IRIF). H2A ubiquitination also mediates the ATM-dependent transcriptional silencing at regions flanking DSBs in cis, a mechanism to avoid collision between transcription and repair intermediates. Also catalyzes the formation of 'Lys-48'-linked polyubiquitin chains, leading to degradation of substrate proteins. In addition to its function in damage signaling, also plays a role in higher-order chromatin structure by mediating extensive chromatin decondensation.
messages: Homodimer. Forms a E2-E3 ubiquitin ligase complex composed of the RNF8 homodimer and a E2 heterodimer of UBE2N and UBE2V2.
messages: Nucleus
messages: The FHA domain specifically recognizes and binds ATM-phosphorylated MDC1.

244447:LOC103390204
gene id: 244447:LOC103390204
uniprot id: A0A3P8WLK1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM38 family.
messages: Membrane
messages: Monovalent cation channel required for maintenance of rapid intracellular calcium release. May act as a potassium counter-ion channel that functions in synchronization with calcium release from intracellular stores.

244447:syndig1l
gene id: 244447:syndig1l
uniprot id: A0A3P8UHE9
names: Similarity
messages: Belongs to the CD225/Dispanin family.

244447:rps15
gene id: 244447:rps15
uniprot id: A0A3P8VV61
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.

244447:LOC103380062
gene id: 244447:LOC103380062
uniprot id: A0A3P8UUB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Cell membrane
messages: Membrane
messages: extracellular exosome

244447:LOC103381988
gene id: 244447:LOC103381988
uniprot id: A0A3P8WRX7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the noggin family.
messages: Homodimer.
messages: Secreted

244447:LOC103393604
gene id: 244447:LOC103393604
uniprot id: A0A3P8W3F7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the COA3 family.
messages: Component of 250-400 kDa complexes called cytochrome oxidase assembly intermediates or COA complexes.
messages: Core component of the MITRAC (mitochondrial translation regulation assembly intermediate of cytochrome c oxidase complex) complex, that regulates cytochrome c oxidase assembly. MITRAC complexes regulate both translation of mitochondrial encoded components and assembly of nuclear-encoded components imported in mitochondrion. Required for efficient translation of MT-CO1 and mitochondrial respiratory chain complex IV assembly.
messages: Membrane
messages: Required for assembly of cytochrome c oxidase (complex IV).

244447:LOC103395841
gene id: 244447:LOC103395841
uniprot id: A0A3P8VRL5
names: Function
names: Similarity
messages: Belongs to the profilin family.
messages: Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG.

244447:LOC103380583
gene id: 244447:LOC103380583
uniprot id: A0A3P8WDJ1
names: Similarity
messages: Belongs to the protein kinase superfamily.

244447:nkx1-2
gene id: 244447:nkx1-2
uniprot id: A0A3P8UPK3
names: Subcellular Location Annotation
messages: Nucleus

244447:LOC103385251
gene id: 244447:LOC103385251
uniprot id: A0A3P8WGA8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the COQ10 family.
messages: Interacts with coenzyme Q.
messages: Required for the function of coenzyme Q in the respiratory chain. May serve as a chaperone or may be involved in the transport of Q6 from its site of synthesis to the catalytic sites of the respiratory complexes.

244447:LOC103394070
gene id: 244447:LOC103394070
uniprot id: A0A3P8VYI2
names: Similarity
messages: Belongs to the carnitine/choline acetyltransferase family.

244447:sec23a
gene id: 244447:sec23a
uniprot id: A0A3P8VYR5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEC23/SEC24 family. SEC23 subfamily.
messages: COPII-coated vesicle membrane
messages: Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: cytosol

244447:adssl1
gene id: 244447:adssl1
uniprot id: A0A3P8UCN4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.
messages: Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis.

244447:LOC103380411
gene id: 244447:LOC103380411
uniprot id: A0A3P8VMT7
names: Similarity
messages: Belongs to the teashirt C2H2-type zinc-finger protein family.

244447:myorg
gene id: 244447:myorg
uniprot id: A0A3P8V7L9
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

244447:LOC103381017
gene id: 244447:LOC103381017
uniprot id: A0A3P8UMN6
names: Similarity
messages: Belongs to the GDA1/CD39 NTPase family.

244447:LOC103398316
gene id: 244447:LOC103398316
uniprot id: A0A3P8WU57
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaves the gamma-glutamyl peptide bond of glutathione and glutathione conjugates.
messages: Membrane

244447:st8sia5
gene id: 244447:st8sia5
uniprot id: A0A3P8UNN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

244447:rab21
gene id: 244447:rab21
uniprot id: A0A3P8WSS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Cleavage furrow
messages: Cytoplasmic vesicle membrane
messages: Early endosome membrane
messages: Endoplasmic reticulum membrane
messages: Endosome membrane
messages: neuron projection
messages: trans-Golgi network

244447:spire2
gene id: 244447:spire2
uniprot id: A0A3P8X4C8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the spire family.
messages: Cell membrane
messages: Cytoplasmic vesicle membrane
messages: Membrane
messages: cytoskeleton

244447:gpd1
gene id: 244447:gpd1
uniprot id: A0A3P8WVL8
names: Similarity
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.

244447:agpat5
gene id: 244447:agpat5
uniprot id: A0A3P8VPP6
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

244447:f13a1
gene id: 244447:f13a1
uniprot id: A0A3P8WSR0
names: Similarity
messages: Belongs to the transglutaminase superfamily. Transglutaminase family.

244447:LOC103389586
gene id: 244447:LOC103389586
uniprot id: A0A3P8V5I6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the X(+)/potassium ATPases subunit beta family.
messages: Cell membrane
messages: Membrane
messages: This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane.

244447:mesd
gene id: 244447:mesd
uniprot id: A0A3P8V785
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MESD family.
messages: Endoplasmic reticulum

244447:LOC103392691
gene id: 244447:LOC103392691
uniprot id: A0A3P8VGN6
names: Subcellular Location Annotation
messages: Nucleus

244447:slc31a1
gene id: 244447:slc31a1
uniprot id: A0A3P8WWY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the copper transporter (Ctr) (TC 1.A.56) family. SLC31A subfamily.
messages: Membrane

244447:cenpm
gene id: 244447:cenpm
uniprot id: A0A3P8VCW9
names: Subcellular Location Annotation
messages: Nucleus

244447:LOC103389307
gene id: 244447:LOC103389307
uniprot id: A0A3P8UN31
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

244447:LOC103394801
gene id: 244447:LOC103394801
uniprot id: A0A3P8W4Z1
names: Similarity
messages: Belongs to the peptidase M10A family.

244447:dennd6a
gene id: 244447:dennd6a
uniprot id: A0A3P8WME6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DENND6 family.
messages: Endosome
messages: Recycling endosome

244447:LOC103388542
gene id: 244447:LOC103388542
uniprot id: H9CIJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

244447:aifm1
gene id: 244447:aifm1
uniprot id: A0A3P8WA83
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase family.

244447:arsi
gene id: 244447:arsi
uniprot id: A0A3P8VVQ7
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

244447:cmtm4
gene id: 244447:cmtm4
uniprot id: A0A3P8UEJ5
names: Subcellular Location Annotation
messages: Membrane

244447:hspa14
gene id: 244447:hspa14
uniprot id: A0A3P8WMA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heat shock protein 70 family.
messages: cytosol

244447:npm3
gene id: 244447:npm3
uniprot id: A0A3P8VGC2
names: Similarity
messages: Belongs to the nucleoplasmin family.

244447:LOC103392711
gene id: 244447:LOC103392711
uniprot id: A0A3P8VIY9
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

244447:snx19
gene id: 244447:snx19
uniprot id: A0A3P8V0Q1
names: Similarity
messages: Belongs to the sorting nexin family.

244447:ptpru
gene id: 244447:ptpru
uniprot id: A0A3P8V2Y3
uniprot id: A0A3P8V5N2
uniprot id: A0A3P8V7Q9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Receptor class 2B subfamily.
messages: Membrane

244447:creg2
gene id: 244447:creg2
uniprot id: A0A3P8V295
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CREG family.
messages: Secreted

244447:LOC103387002
gene id: 244447:LOC103387002
uniprot id: A0A3P8UPH6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat coronin family.
messages: Regulates leading edge dynamics and cell motility in fibroblasts. May be involved in cytokinesis and signal transduction.
messages: stress fiber

244447:cryl1
gene id: 244447:cryl1
uniprot id: A0A3P8VHX1
names: Similarity
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

244447:LOC103389517
gene id: 244447:LOC103389517
uniprot id: A0A3P8V338
names: Similarity
messages: Belongs to the TTC39 family.

244447:LOC103388376
gene id: 244447:LOC103388376
uniprot id: A0A3P8UYR2
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

244447:vps25
gene id: 244447:vps25
uniprot id: A0A3P8VDL9
names: Similarity
messages: Belongs to the VPS25 family.

244447:mphosph10
gene id: 244447:mphosph10
uniprot id: A0A3P8UJH8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MPP10 family.
messages: Component of the 60-80S U3 small nucleolar ribonucleoprotein (U3 snoRNP). Required for the early cleavages during pre-18S ribosomal RNA processing.
messages: nucleolus

244447:mpp3
gene id: 244447:mpp3
uniprot id: A0A3P8VNV7
uniprot id: A0A3P8VP11
uniprot id: A0A3P8VP29
names: Similarity
messages: Belongs to the MAGUK family.

244447:LOC103389940
gene id: 244447:LOC103389940
uniprot id: A0A3P8W0T7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-1 family.
messages: Lysosome
messages: cytosol
messages: extracellular exosome

244447:LOC103384186
gene id: 244447:LOC103384186
uniprot id: A0A3P8WAY0
names: Caution
names: Similarity
messages: Belongs to the peptidase M14 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

244447:LOC103382524
gene id: 244447:LOC103382524
uniprot id: A0A3P8UXI1
names: Similarity
messages: Belongs to the type II (or gamma) interferon family.

244447:LOC103388423
gene id: 244447:LOC103388423
uniprot id: A0A3P8V003
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus

244447:casd1
gene id: 244447:casd1
uniprot id: A0A3P8VYL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PC-esterase family. CASD1 subfamily.
messages: Membrane

244447:kitlg
gene id: 244447:kitlg
uniprot id: A0A3P8X2D1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCF family.
messages: Cytoplasm
messages: Secreted
messages: filopodium
messages: lamellipodium

244447:LOC103396959
gene id: 244447:LOC103396959
uniprot id: A0A3P8VI79
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

244447:cpped1
gene id: 244447:cpped1
uniprot id: A0A3P8WVA3
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. CPPED1 family.

244447:fitm2
gene id: 244447:fitm2
uniprot id: A0A3P8VP89
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

244447:camsap3
gene id: 244447:camsap3
uniprot id: A0A3P8VWC2
uniprot id: A0A3P8W264
names: Domain
names: Similarity
messages: Belongs to the CAMSAP1 family.
messages: The CKK domain binds microtubules.

244447:LOC103381542
gene id: 244447:LOC103381542
uniprot id: A0A3P8VQG4
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

244447:sgcd
gene id: 244447:sgcd
uniprot id: A0A3P8WX44
uniprot id: A0A3P8X2T0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sarcoglycan beta/delta/gamma/zeta family.
messages: cytoskeleton
messages: sarcolemma

244447:LOC103390053
gene id: 244447:LOC103390053
uniprot id: A0A3P8W6K4
uniprot id: A0A3P8W9I2
names: Subcellular Location Annotation
messages: Secreted
messages: Synapse

244447:exosc9
gene id: 244447:exosc9
uniprot id: A0A3P8W8B4
names: Subcellular Location Annotation
messages: Cytoplasm

244447:LOC103391687
gene id: 244447:LOC103391687
uniprot id: A0A3P8V1V9
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.

244447:adcy5
gene id: 244447:adcy5
uniprot id: A0A3P8V447
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Binds 2 magnesium ions per subunit. Is also active with manganese (in vitro).
messages: Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.
messages: Membrane

244447:rab39b
gene id: 244447:rab39b
uniprot id: A0A3P8WN91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Cell membrane
messages: Membrane

244447:LOC103392496
gene id: 244447:LOC103392496
uniprot id: A0A3P8WTP5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

244447:ppara
gene id: 244447:ppara
uniprot id: A0A3P8VXK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

244447:LOC103379376
gene id: 244447:LOC103379376
uniprot id: A0A3P8W2I6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Membrane
messages: cis-Golgi network membrane

244447:prrt1
gene id: 244447:prrt1
uniprot id: A0A3P8VR00
names: Similarity
messages: Belongs to the CD225/Dispanin family.

244447:dhrs7
gene id: 244447:dhrs7
uniprot id: A0A3P8UIM0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

244447:LOC103378725
gene id: 244447:LOC103378725
uniprot id: A0A3P8UIZ2
names: Similarity
messages: Belongs to the GTP cyclohydrolase I family.

244447:LOC103383297
gene id: 244447:LOC103383297
uniprot id: A0A3P8X5Q7
names: Subcellular Location Annotation
messages: Nucleus

244447:LOC103395457
gene id: 244447:LOC103395457
uniprot id: A0A3P8WN13
names: Subcellular Location Annotation
messages: Nucleus

244447:LOC103394397
gene id: 244447:LOC103394397
uniprot id: A0A3P8WJF9
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

244447:LOC103392690
gene id: 244447:LOC103392690
uniprot id: A0A3P8X6X1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PPP phosphatase family. PP-1 subfamily.
messages: Cytoplasm

244447:LOC103397629
gene id: 244447:LOC103397629
uniprot id: A0A3P8WUS3
names: Cofactor
names: Function
names: Subunit
messages: Binds 1 zinc ion per subunit.
messages: Homotetramer.
messages: Involved in the regulation of homocysteine metabolism.

244447:LOC103378320
gene id: 244447:LOC103378320
uniprot id: A0A3P8WDP6
names: Subcellular Location Annotation
messages: Membrane

244447:tead3
gene id: 244447:tead3
uniprot id: A0A3P8WED0
uniprot id: A0A3P8WF78
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis.

244447:adnp
gene id: 244447:adnp
uniprot id: A0A3P8UWA7
names: Subcellular Location Annotation
messages: Nucleus

244447:pmp22
gene id: 244447:pmp22
uniprot id: A0A3P8W5P4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Might be involved in growth regulation, and in myelinization in the peripheral nervous system.

244447:psmd5
gene id: 244447:psmd5
uniprot id: A0A3P8UIA6
names: Similarity
messages: Belongs to the proteasome subunit S5B/HSM3 family.

244447:phc3
gene id: 244447:phc3
uniprot id: A0A3P8W542
names: Subcellular Location Annotation
messages: Nucleus

244447:slc25a28
gene id: 244447:slc25a28
uniprot id: A0A3P8V649
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

244447:LOC103379817
gene id: 244447:LOC103379817
uniprot id: A0A3P8UL27
names: Similarity
messages: Belongs to the iron/ascorbate-dependent oxidoreductase family.

244447:LOC103390636
gene id: 244447:LOC103390636
uniprot id: A0A3P8US77
names: Subcellular Location Annotation
messages: Membrane

244447:LOC103386272
gene id: 244447:LOC103386272
uniprot id: A0A3P8VJ73
names: Subcellular Location Annotation
messages: Membrane

244447:avpr1a
gene id: 244447:avpr1a
uniprot id: A0A3P8UY60
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

244447:anpep
gene id: 244447:anpep
uniprot id: A0A3P8UER9
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.

244447:panx2
gene id: 244447:panx2
uniprot id: A0A3P8VQX6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pannexin family.
messages: Cell membrane
messages: Membrane
messages: Structural component of the gap junctions and the hemichannels.
messages: gap junction

244447:ndufv2
gene id: 244447:ndufv2
uniprot id: A0A3P8WLD2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.

244447:LOC103388843
gene id: 244447:LOC103388843
uniprot id: A0A3P8VV73
names: Subcellular Location Annotation
messages: Membrane

244447:p4hb
gene id: 244447:p4hb
uniprot id: A0A3P8WHM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein disulfide isomerase family.
messages: Endoplasmic reticulum lumen

244447:trmt1l
gene id: 244447:trmt1l
uniprot id: A0A3P8UF84
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family.
messages: May play a role in motor coordination and exploratory behavior.

244447:usp49
gene id: 244447:usp49
uniprot id: A0A3P8UJR6
names: Similarity
messages: Belongs to the peptidase C19 family.

244447:rspo2
gene id: 244447:rspo2
uniprot id: A0A0K0MV72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the R-spondin family.
messages: Secreted

244447:LOC103390753
gene id: 244447:LOC103390753
uniprot id: A0A3P8UWF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
messages: Cell membrane
messages: Membrane

244447:pmpcb
gene id: 244447:pmpcb
uniprot id: A0A3P8VK81
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase M16 family.
messages: Heterodimer of PMPCA (alpha) and PMPCB (beta) subunits, forming the mitochondrial processing protease (MPP) in which PMPCA is involved in substrate recognition and binding and PMPCB is the catalytic subunit.
messages: Mitochondrion matrix

244447:ddx20
gene id: 244447:ddx20
uniprot id: A0A3P8WSQ0
names: Similarity
messages: Belongs to the DEAD box helicase family.

244447:LOC103379240
gene id: 244447:LOC103379240
uniprot id: A0A2Z5VHI2
names: Caution
names: Cofactor
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

244447:dmrt1
gene id: 244447:dmrt1
uniprot id: A0A3P8WTZ3
uniprot id: A8TT10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DMRT family.
messages: Nucleus

244447:glod4
gene id: 244447:glod4
uniprot id: A0A3P8W0V5
names: Similarity
messages: Belongs to the glyoxalase I family.

244447:hepacam2
gene id: 244447:hepacam2
uniprot id: A0A3P8VZI2
names: Subcellular Location Annotation
messages: Membrane

244447:LOC103391512
gene id: 244447:LOC103391512
uniprot id: A0A3P8X062
names: Similarity
messages: Belongs to the peptidase S51 family.

244447:ptar1
gene id: 244447:ptar1
uniprot id: A0A3P8VKZ6
names: Similarity
messages: Belongs to the protein prenyltransferase subunit alpha family.

244447:LOC103397582
gene id: 244447:LOC103397582
uniprot id: A0A3P8WFX7
names: Similarity
messages: Belongs to the nucleosome assembly protein (NAP) family.

244447:brk1
gene id: 244447:brk1
uniprot id: A0A3P8UJT7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BRK1 family.
messages: cytoskeleton

244447:LOC103378083
gene id: 244447:LOC103378083
uniprot id: A0A3P8VF58
names: Similarity
messages: Belongs to the CD225/Dispanin family.

244447:LOC103390772
gene id: 244447:LOC103390772
uniprot id: A0A3P8V4N9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GLI C2H2-type zinc-finger protein family.
messages: Nucleus

244447:saraf
gene id: 244447:saraf
uniprot id: A0A3P8WDF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SARAF family.
messages: Endoplasmic reticulum membrane
messages: Membrane

244447:wasf3
gene id: 244447:wasf3
uniprot id: A0A3P8WGQ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SCAR/WAVE family.
messages: Binds actin and the Arp2/3 complex.
messages: Downstream effector molecule involved in the transmission of signals from tyrosine kinase receptors and small GTPases to the actin cytoskeleton. Promotes formation of actin filaments. Part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex.
messages: cytoskeleton

244447:pex16
gene id: 244447:pex16
uniprot id: A0A3P8VAC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxin-16 family.
messages: Peroxisome membrane

244447:LOC103392607
gene id: 244447:LOC103392607
uniprot id: A0A3P8X5H9
names: Similarity
messages: Belongs to the formin homology family.

244447:foxm1
gene id: 244447:foxm1
uniprot id: A0A3P8VHH7
names: Subcellular Location Annotation
messages: Nucleus

244447:hvcn1
gene id: 244447:hvcn1
uniprot id: A0A3P8UV50
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the hydrogen channel family.
messages: Homodimer.
messages: Membrane

244447:LOC103394463
gene id: 244447:LOC103394463
uniprot id: A0A3P8WW48
names: Similarity
messages: Belongs to the MS4A family.

244447:LOC103391951
gene id: 244447:LOC103391951
uniprot id: A0A3P8VKM6
names: Similarity
messages: Belongs to the peptidase C48 family.

244447:kcnb2
gene id: 244447:kcnb2
uniprot id: A0A3P8VJQ4
names: Subcellular Location Annotation
messages: Membrane
messages: Perikaryon

244447:LOC103391104
gene id: 244447:LOC103391104
uniprot id: A0A3P8W0R6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the shootin family.
messages: axon
messages: cytoskeleton
messages: filopodium
messages: lamellipodium

244447:mus81
gene id: 244447:mus81
uniprot id: A0A3P8ULU2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XPF family.
messages: Interacts with EME1 to form a DNA structure-specific endonuclease with substrate preference for branched DNA structures with a 5'-end at the branch nick. Typical substrates include 3'-flap structures, D-loops, replication forks and nicked Holliday junctions. May be required in mitosis for the processing of stalled or collapsed replication fork intermediates. May be required in meiosis for the repair of meiosis-specific double strand breaks subsequent to single-end invasion (SEI).
messages: Interacts with EME1.
messages: Nucleus

244447:tfap2c
gene id: 244447:tfap2c
uniprot id: A0A3P8WQS6
uniprot id: A0A3P8WQT1
names: Similarity
messages: Belongs to the AP-2 family.

244447:ints8
gene id: 244447:ints8
uniprot id: A0A3P8VIG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Integrator subunit 8 family.
messages: Nucleus

244447:LOC103392550
gene id: 244447:LOC103392550
uniprot id: A0A3P8X5E4
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

244447:LOC103387923
gene id: 244447:LOC103387923
uniprot id: A0A3P8WYG9
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

244447:LOC103391683
gene id: 244447:LOC103391683
uniprot id: A0A3P8UT70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LAMP family.
messages: Endosome membrane

244447:lap3
gene id: 244447:lap3
uniprot id: A0A3P8VTJ6
names: Similarity
names: Subunit
messages: Belongs to the peptidase M17 family.
messages: Homohexamer.

244447:tmem200a
gene id: 244447:tmem200a
uniprot id: A0A3P8WTJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM200 family.
messages: Membrane

244447:LOC103399738
gene id: 244447:LOC103399738
uniprot id: A0A3P8UPH9
names: Similarity
messages: Belongs to the carotenoid oxygenase family.

244447:ube2k
gene id: 244447:ube2k
uniprot id: A0A3P8V2X7
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

244447:pcyox1l
gene id: 244447:pcyox1l
uniprot id: A0A3P8WR03
names: Similarity
messages: Belongs to the prenylcysteine oxidase family.

244447:mrpl11
gene id: 244447:mrpl11
uniprot id: A0A3P8UYP2
names: Similarity
messages: Belongs to the universal ribosomal protein uL11 family.

244447:slc29a3
gene id: 244447:slc29a3
uniprot id: A0A3P8VTS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC29A/ENT transporter (TC 2.A.57) family.
messages: Membrane

244447:barx2
gene id: 244447:barx2
uniprot id: A0A3P8USS5
names: Subcellular Location Annotation
messages: Nucleus

244447:scamp3
gene id: 244447:scamp3
uniprot id: A0A3P8VI88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCAMP family.
messages: Membrane

244447:slc6a1
gene id: 244447:slc6a1
uniprot id: A0A3P8X6U3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

244447:adam10
gene id: 244447:adam10
uniprot id: A0A3P8UNY4
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

244447:cmc2
gene id: 244447:cmc2
uniprot id: A0A3P8WBN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CMC family.
messages: Mitochondrion

244447:LOC103380027
gene id: 244447:LOC103380027
uniprot id: A0A3P8UYB2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BCAP29/BCAP31 family.
messages: Endoplasmic reticulum membrane
messages: May play a role in anterograde transport of membrane proteins from the endoplasmic reticulum to the Golgi.
messages: Membrane

244447:hspa4l
gene id: 244447:hspa4l
uniprot id: A0A3P8UNV3
names: Similarity
messages: Belongs to the heat shock protein 70 family.

244447:LOC103386109
gene id: 244447:LOC103386109
uniprot id: A0A3P8UWK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Cytoplasm
messages: Nucleus

244447:LOC103398781
gene id: 244447:LOC103398781
uniprot id: A0A3P8UKH7
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

244447:polg
gene id: 244447:polg
uniprot id: A0A097RN08
uniprot id: A0A3P8W6Z7
names: Function
names: Subcellular Location Annotation
messages: Involved in the replication of mitochondrial DNA. Associates with mitochondrial DNA.
messages: mitochondrion nucleoid

244447:phox2b
gene id: 244447:phox2b
uniprot id: A0A3P8UV67
names: Subcellular Location Annotation
messages: Nucleus

244447:aspm
gene id: 244447:aspm
uniprot id: A0A3P8UQZ5
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

244447:hnf1a
gene id: 244447:hnf1a
uniprot id: A0A3P8VSE4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HNF1 homeobox family.
messages: Nucleus

244447:ccdc22
gene id: 244447:ccdc22
uniprot id: A0A3P8V091
names: Similarity
messages: Belongs to the CCDC22 family.

244447:LOC103392803
gene id: 244447:LOC103392803
uniprot id: A0A3P8VRU8
names: Subcellular Location Annotation
messages: Membrane

244447:LOC103395531
gene id: 244447:LOC103395531
uniprot id: A0A3P8WZT5
names: Function
names: Similarity
messages: Belongs to the arrestin family.
messages: May play a role in an as yet undefined retina-specific signal transduction. Could bind to photoactivated-phosphorylated red/green opsins.

244447:LOC103382659
gene id: 244447:LOC103382659
uniprot id: A0A3P8V346
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.
messages: Nucleus

244447:LOC103386180
gene id: 244447:LOC103386180
uniprot id: A0A3P8V0S7
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.

244447:LOC103392801
gene id: 244447:LOC103392801
uniprot id: A0A3P8VP96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family. KCNJ2 subfamily.
messages: Membrane

244447:LOC103389390
gene id: 244447:LOC103389390
uniprot id: A0A3P8UT05
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.

244447:LOC103391404
gene id: 244447:LOC103391404
uniprot id: A0A3P8X2J8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.

244447:LOC103388545
gene id: 244447:LOC103388545
uniprot id: A0A3P8V1D5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TDE1 family.
messages: Membrane

244447:LOC103397571
gene id: 244447:LOC103397571
uniprot id: A0A3P8WI29
names: Similarity
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. RAF subfamily.

244447:rpl30
gene id: 244447:rpl30
uniprot id: A0A3P8WR48
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL30 family.

244447:eps8l2
gene id: 244447:eps8l2
uniprot id: A0A3P8VBZ4
uniprot id: A0A3P8VC07
uniprot id: A0A3P8VC31
names: Similarity
messages: Belongs to the EPS8 family.

244447:hps5
gene id: 244447:hps5
uniprot id: A0A3P8VC82
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPS5 family.
messages: Component of the biogenesis of lysosome-related organelles complex-2 (or BLOC2) composed of HPS3, HPS5 and HPS6.
messages: May regulate the synthesis and function of lysosomes and of highly specialized organelles, such as melanosomes and platelet dense granules.
messages: cytosol

244447:fam187a
gene id: 244447:fam187a
uniprot id: A0A3P8VCA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM187 family.
messages: Membrane

244447:LOC103395083
gene id: 244447:LOC103395083
uniprot id: A0A3P8VL76
uniprot id: A0A3P8VNK0
names: Similarity
messages: Belongs to the adaptor complexes large subunit family.

244447:LOC103388995
gene id: 244447:LOC103388995
uniprot id: A0A3P8V3N8
names: Similarity
messages: Belongs to the cytochrome P450 family.

244447:LOC103398235
gene id: 244447:LOC103398235
uniprot id: A0A3P8WEA4
names: Function
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of long-chain fatty acids to their active form acyl-CoAs for both synthesis of cellular lipids, and degradation via beta-oxidation.

244447:lhfpl6
gene id: 244447:lhfpl6
uniprot id: A0A3P8V692
names: Subcellular Location Annotation
messages: Membrane

244447:LOC103376718
gene id: 244447:LOC103376718
uniprot id: A0A3P8UK22
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

244447:lypla1
gene id: 244447:lypla1
uniprot id: A0A3P8X2Q2
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 2 family.

244447:LOC103392511
gene id: 244447:LOC103392511
uniprot id: A0A3P8X4D2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSG1 family.
messages: Membrane

244447:LOC103396494
gene id: 244447:LOC103396494
uniprot id: A0A3P8WIP6
uniprot id: A0A3P8WIQ4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

244447:bud23
gene id: 244447:bud23
uniprot id: A0A3P8WL21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. BUD23/WBSCR22 family.
messages: Cytoplasm
messages: Nucleus

244447:gbe1
gene id: 244447:gbe1
uniprot id: A0A3P8VMD4
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.

244447:LOC103388971
gene id: 244447:LOC103388971
uniprot id: A0A3P8WAC9
names: Subcellular Location Annotation
messages: Membrane

244447:LOC103381972
gene id: 244447:LOC103381972
uniprot id: A0A3P8WLP3
names: Subcellular Location Annotation
messages: Membrane

244447:LOC103393264
gene id: 244447:LOC103393264
uniprot id: A0A3P8WUE5
names: Function
names: Similarity
messages: Belongs to the parvalbumin family.
messages: In muscle, parvalbumin is thought to be involved in relaxation after contraction. It binds two calcium ions.

244447:igflr1
gene id: 244447:igflr1
uniprot id: A0A3P8VAV8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

244447:mdfic
gene id: 244447:mdfic
uniprot id: A0A3P8VN68
names: Similarity
messages: Belongs to the MDFI family.

244447:usp16
gene id: 244447:usp16
uniprot id: A0A3P8VLE1
names: Similarity
messages: Belongs to the peptidase C19 family.

244447:tmem43
gene id: 244447:tmem43
uniprot id: A0A3P8ULX7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM43 family.
messages: Membrane

244447:LOC103386409
gene id: 244447:LOC103386409
uniprot id: A0A3P8VY73
names: Subcellular Location Annotation
messages: Nucleus

244447:smoc2
gene id: 244447:smoc2
uniprot id: A0A3P8WKX1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

244447:psma2
gene id: 244447:psma2
uniprot id: A0A3P8VWN8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Cytoplasm
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.

244447:rbpj
gene id: 244447:rbpj
uniprot id: A0A3P8V1Y9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Su(H) family.
messages: Nucleus

244447:ripor3
gene id: 244447:ripor3
uniprot id: A0A3P8WC16
names: Similarity
messages: Belongs to the RIPOR family.

244447:LOC103379234
gene id: 244447:LOC103379234
uniprot id: A0A3P8VLP8
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Interacts with ATP6V0C.
messages: Membrane

244447:LOC103394433
gene id: 244447:LOC103394433
uniprot id: A0A3P8WLD8
names: Similarity
messages: Belongs to the FAM83 family.

244447:LOC103385408
gene id: 244447:LOC103385408
uniprot id: A0A3P8X5K2
names: Similarity
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.

244447:polr2k
gene id: 244447:polr2k
uniprot id: A0A3P8WL44
names: Similarity
messages: Belongs to the archaeal Rpo12/eukaryotic RPC10 RNA polymerase subunit family.

244447:LOC103395808
gene id: 244447:LOC103395808
uniprot id: A0A3P8VNB9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. ERG27 subfamily.

244447:tp53inp1
gene id: 244447:tp53inp1
uniprot id: A0A3P8WYV6
names: Subcellular Location Annotation
messages: PML body
messages: autophagosome
messages: cytosol

244447:LOC103395882
gene id: 244447:LOC103395882
uniprot id: A0A3P8W0J7
names: Similarity
messages: Belongs to the PI3K p85 subunit family.

244447:cdc42ep4
gene id: 244447:cdc42ep4
uniprot id: A0A3P8W2Y5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BORG/CEP family.
messages: Endomembrane system

244447:trappc6b
gene id: 244447:trappc6b
uniprot id: A0A3P8V4F5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAPP small subunits family. BET3 subfamily.
messages: Endoplasmic reticulum
messages: cis-Golgi network

244447:LOC103389006
gene id: 244447:LOC103389006
uniprot id: A0A3P8WB09
names: Similarity
messages: Belongs to the cullin family.

244447:LOC103379378
gene id: 244447:LOC103379378
uniprot id: A0A3P8VWS7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

244447:igf2
gene id: 244447:igf2
uniprot id: B9VVQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the insulin family.
messages: Secreted

244447:sulf1
gene id: 244447:sulf1
uniprot id: A0A3P8W730
uniprot id: A0A3P8W754
names: Cofactor
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfatase family.
messages: Binds 1 Ca(2+) ion per subunit.
messages: Cell surface
messages: Endoplasmic reticulum
messages: Golgi stack
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

244447:rpl10a
gene id: 244447:rpl10a
uniprot id: A0A3P8URG5
names: Similarity
messages: Belongs to the universal ribosomal protein uL1 family.

244447:polr3a
gene id: 244447:polr3a
uniprot id: A0A3P8WF48
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Component of the RNA polymerase III (Pol III) complex consisting of 17 subunits.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Nucleus

244447:ckb
gene id: 244447:ckb
uniprot id: A0A3P8W4Y6
names: Similarity
messages: Belongs to the ATP:guanido phosphotransferase family.

244447:LOC103393294
gene id: 244447:LOC103393294
uniprot id: A0A3P8V514
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 2 family.
messages: Golgi apparatus membrane
messages: Membrane

244447:LOC103376740
gene id: 244447:LOC103376740
uniprot id: A0A3P8VB77
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

244447:LOC103385972
gene id: 244447:LOC103385972
uniprot id: A0A3P8UXQ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bZIP family.
messages: Homodimer; binds DNA as homodimer. Heterodimer; heterodimerizes with other members of ATF family and with JUN family members.
messages: Nucleus
messages: Stress-responsive chromatin regulator that plays a role in various biological processes including innate immunological memory, adipocyte differentiation or telomerase regulation. In absence of stress, contributes to the formation of heterochromatin and heterochromatin-like structure by recruiting histone H3K9 tri- and di-methyltransferases thus silencing the transcription of target genes such as STAT1 in adipocytes, or genes involved in innate immunity in macrophages and adipocytes. Stress induces ATF7 phosphorylation that disrupts interactions with histone methyltransferase and enhances the association with coactivators containing histone acetyltransferase and/or histone demethylase, leading to disruption of the heterochromatin-like structure and subsequently transcriptional activation. In response to TNF-alpha, which is induced by various stresses, phosphorylated ATF7 and telomerase are released from telomeres leading to telomere shortening.

244447:LOC103379701
gene id: 244447:LOC103379701
uniprot id: A0A3P8X484
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acyl-CoA reductase family.
messages: Catalyzes the reduction of fatty acyl-CoA to fatty alcohols.
messages: Peroxisome membrane

244447:LOC103377889
gene id: 244447:LOC103377889
uniprot id: A0A3P8V3U0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

244447:LOC103393002
gene id: 244447:LOC103393002
uniprot id: A0A3P8WBF3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Cytoplasm
messages: Homodimer and heterodimer with SSTR3 and SSTR5. Heterodimerization with SSTR3 inactivates SSTR3 receptor function. Heterodimerization with SSTR5 is enhanced by agonist stimulation of SSTR2 and increases SSTR2 cell growth inhibition activity. Following agonist stimulation, homodimers dissociate into monomers which is required for receptor internalization. Interacts with beta-arrestin; this interaction is necessary for receptor internalization and is destabilized by heterodimerization with SSTR5 which results in increased recycling of SSTR2 to the cell surface. Interacts (via C-terminus) with SHANK1 (via PDZ domain).
messages: Membrane
messages: Receptor for somatostatin-14 and -28. This receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase. In addition it stimulates phosphotyrosine phosphatase and PLC via pertussis toxin insensitive as well as sensitive G proteins. Inhibits calcium entry by suppressing voltage-dependent calcium channels. Acts as the functionally dominant somatostatin receptor in pancreatic alpha- and beta-cells where it mediates the inhibitory effect of somatostatin-14 on hormone secretion. Inhibits cell growth through enhancement of MAPK1 and MAPK2 phosphorylation and subsequent up-regulation of CDKN1B. Stimulates neuronal migration and axon outgrowth and may participate in neuron development and maturation during brain development. Mediates negative regulation of insulin receptor signaling through PTPN6. Inactivates SSTR3 receptor function following heterodimerization.

244447:vim
gene id: 244447:vim
uniprot id: A0A3P8VZH4
names: Function
names: Similarity
messages: Belongs to the intermediate filament family.
messages: Vimentins are class-III intermediate filaments found in various non-epithelial cells, especially mesenchymal cells. Vimentin is attached to the nucleus, endoplasmic reticulum, and mitochondria, either laterally or terminally.

244447:gpr155
gene id: 244447:gpr155
uniprot id: A0A3P8V690
names: Subcellular Location Annotation
messages: Membrane

244447:nsdhl
gene id: 244447:nsdhl
uniprot id: A0A3P8W7P8
names: Similarity
messages: Belongs to the 3-beta-HSD family.

244447:setd3
gene id: 244447:setd3
uniprot id: A0A3P8US39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class V-like SAM-binding methyltransferase superfamily. SETD3 actin-histidine methyltransferase family.
messages: Cytoplasm

244447:serpind1
gene id: 244447:serpind1
uniprot id: A0A3P8WUH4
names: Similarity
messages: Belongs to the serpin family.

244447:tm4sf5
gene id: 244447:tm4sf5
uniprot id: A0A3P8V3C1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L6 tetraspanin family.
messages: Membrane

244447:kif19
gene id: 244447:kif19
uniprot id: A0A3P8WA15
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

244447:LOC103397981
gene id: 244447:LOC103397981
uniprot id: A0A3P8VFF3
names: Similarity
messages: Belongs to the alpha-ketoglutarate dehydrogenase family.

244447:epg5
gene id: 244447:epg5
uniprot id: A0A3P8WC43
names: Similarity
messages: Belongs to the EPG5 family.

244447:irx2
gene id: 244447:irx2
uniprot id: A0A3P8UZE7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/IRO homeobox family.
messages: Nucleus

244447:ube2c
gene id: 244447:ube2c
uniprot id: A0A3P8X3W1
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

244447:LOC103383790
gene id: 244447:LOC103383790
uniprot id: A0A3P8V9L7
names: Function
names: Similarity
messages: Belongs to the rod/cone cGMP-PDE gamma subunit family.
messages: Participates in processes of transmission and amplification of the visual signal. cGMP-PDEs are the effector molecules in G-protein-mediated phototransduction in vertebrate rods and cones.

244447:vps41
gene id: 244447:vps41
uniprot id: A0A3P8WX35
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS41 family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane
messages: Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport pathways.
messages: Vesicle
messages: clathrin-coated vesicle
messages: trans-Golgi network

244447:LOC103394920
gene id: 244447:LOC103394920
uniprot id: A0A3P8WIR6
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

244447:LOC103380194
gene id: 244447:LOC103380194
uniprot id: A0A3P8V519
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

244447:dpf1
gene id: 244447:dpf1
uniprot id: A0A3P8WAW1
names: Similarity
messages: Belongs to the requiem/DPF family.

244447:LOC103379239
gene id: 244447:LOC103379239
uniprot id: A0A2Z5VHI2
names: Caution
names: Cofactor
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

244447:LOC103395374
gene id: 244447:LOC103395374
uniprot id: A0A3P8WB90
names: Subcellular Location Annotation
messages: Membrane

244447:LOC103379416
gene id: 244447:LOC103379416
uniprot id: A0A3P8W0R2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCAMP family.
messages: Membrane

244447:slc45a1
gene id: 244447:slc45a1
uniprot id: A0A3P8X661
names: Subcellular Location Annotation
messages: Membrane

244447:stx5
gene id: 244447:stx5
uniprot id: A0A3P8V4A2
uniprot id: A0A3P8V924
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the syntaxin family.
messages: Membrane

244447:LOC103384365
gene id: 244447:LOC103384365
uniprot id: A0A3P8WGU1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

244447:il10
gene id: 244447:il10
uniprot id: A0A3P8UYN6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-10 family.
messages: Immune regulatory cytokine.
messages: Secreted

244447:b4galnt4
gene id: 244447:b4galnt4
uniprot id: A0A3P8VJ88
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chondroitin N-acetylgalactosaminyltransferase family.
messages: Golgi stack membrane
messages: Membrane
messages: Transfers N-acetylgalactosamine (GalNAc) from UDP-GalNAc to N-acetylglucosamine-beta-benzyl with a beta-1,4-linkage to form N,N'-diacetyllactosediamine, GalNAc-beta-1,4-GlcNAc structures in N-linked glycans and probably O-linked glycans.

244447:LOC103379161
gene id: 244447:LOC103379161
uniprot id: A0A3P8WB54
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase IV family.
messages: Component of the cytochrome c oxidase (complex IV, CIV), a multisubunit enzyme composed of 14 subunits.
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.
messages: Membrane
messages: Mitochondrion inner membrane

244447:LOC103394480
gene id: 244447:LOC103394480
uniprot id: A0A2K8ESY2
names: Similarity
messages: Belongs to the tumor necrosis factor family.

244447:b9d1
gene id: 244447:b9d1
uniprot id: A0A3P8WNB6
names: Subcellular Location Annotation
messages: cilium basal body

244447:oxtr
gene id: 244447:oxtr
uniprot id: A0A3P8UN96
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

244447:LOC103389003
gene id: 244447:LOC103389003
uniprot id: A0A3P8WB89
names: Subcellular Location Annotation
messages: extracellular space

244447:LOC103377596
gene id: 244447:LOC103377596
uniprot id: A0A3P8UN09
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

244447:ypel5
gene id: 244447:ypel5
uniprot id: A0A3P8UXH5
names: Similarity
messages: Belongs to the yippee family.

244447:mboat2
gene id: 244447:mboat2
uniprot id: A0A3P8USB1
names: Subcellular Location Annotation
messages: Membrane

244447:LOC103384626
gene id: 244447:LOC103384626
uniprot id: A0A3P8UMV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transcription factor STAT family.
messages: Cytoplasm
messages: Nucleus

244447:ndufa8
gene id: 244447:ndufa8
uniprot id: A0A3P8WJE5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFA8 subunit family.
messages: Mitochondrion inner membrane
messages: Mitochondrion intermembrane space

244447:uncx
gene id: 244447:uncx
uniprot id: A0A3P8X553
names: Subcellular Location Annotation
messages: Nucleus

244447:mocs1
gene id: 244447:mocs1
uniprot id: A0A3P8WN03
names: Similarity
messages: In the C-terminal section; belongs to the MoaC family.
messages: In the N-terminal section; belongs to the radical SAM superfamily. MoaA family.

244447:LOC103397823
gene id: 244447:LOC103397823
uniprot id: A0A3P8WX01
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IL-12B family.
messages: Heterodimer with IL12A; disulfide-linked. The heterodimer is known as interleukin IL-12.
messages: Secreted

244447:tfap2a
gene id: 244447:tfap2a
uniprot id: A0A3P8VJG8
uniprot id: A0A3P8VMH8
uniprot id: A0A3P8VPS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AP-2 family.
messages: Nucleus

244447:pex19
gene id: 244447:pex19
uniprot id: A0A3P8X0Q4
uniprot id: A0A3P8X2K9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxin-19 family.
messages: Interacts with a broad range of peroxisomal membrane proteins, including PEX3, PEX10, PEX11A, PEX11B, PEX12, PEX13, PEX14 and PEX16, PXMP2/PMP22, PXMP4/PMP24, SLC25A17/PMP34, ABCD1/ALDP, ABCD2/ALDRP, and ABCD3/PMP70. Also interacts with the tumor suppressor CDKN2A/p19ARF.
messages: Necessary for early peroxisomal biogenesis. Acts both as a cytosolic chaperone and as an import receptor for peroxisomal membrane proteins (PMPs). Binds and stabilizes newly synthesized PMPs in the cytoplasm by interacting with their hydrophobic membrane-spanning domains, and targets them to the peroxisome membrane by binding to the integral membrane protein PEX3. Excludes CDKN2A from the nucleus and prevents its interaction with MDM2, which results in active degradation of TP53.
messages: Peroxisome membrane

244447:LOC103388715
gene id: 244447:LOC103388715
uniprot id: A0A3P8VN95
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

244447:LOC103392895
gene id: 244447:LOC103392895
uniprot id: A0A3P8W1V0
names: Function
names: Similarity
messages: Belongs to the parvalbumin family.
messages: In muscle, parvalbumin is thought to be involved in relaxation after contraction. It binds two calcium ions.

244447:rnf40
gene id: 244447:rnf40
uniprot id: A0A3P8VYE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BRE1 family.
messages: Nucleus

244447:LOC103386020
gene id: 244447:LOC103386020
uniprot id: A0A3P8UUL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

244447:nipal2
gene id: 244447:nipal2
uniprot id: A0A3P8VH47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NIPA family.
messages: Membrane

244447:LOC103389824
gene id: 244447:LOC103389824
uniprot id: A0A3P8VJB0
names: Similarity
messages: Belongs to the small GTPase superfamily. Ras family.

244447:LOC103388831
gene id: 244447:LOC103388831
uniprot id: A0A3P8W2C7
names: Similarity
messages: Belongs to the intermediate filament family.

244447:shox2
gene id: 244447:shox2
uniprot id: A0A3P8WN79
names: Subcellular Location Annotation
messages: Nucleus

244447:kif23
gene id: 244447:kif23
uniprot id: A0A3P8V7C4
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

244447:LOC103383749
gene id: 244447:LOC103383749
uniprot id: A0A3P8VAW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCAF family.
messages: Nucleus

244447:LOC103394104
gene id: 244447:LOC103394104
uniprot id: A0A3P8VVF9
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

244447:gdap1
gene id: 244447:gdap1
uniprot id: A0A3P8VKK0
names: Similarity
messages: Belongs to the GST superfamily.

244447:olfm3
gene id: 244447:olfm3
uniprot id: A0A3P8W8T3
names: Subcellular Location Annotation
messages: Secreted
messages: Synapse

244447:cfh
gene id: 244447:cfh
uniprot id: A0A0U3QS86
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

244447:LOC103389754
gene id: 244447:LOC103389754
uniprot id: A0A3P8W433
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.

244447:LOC103385080
gene id: 244447:LOC103385080
uniprot id: A0A3P8VC73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family. Beta3-Gal-T subfamily.
messages: Membrane

244447:LOC103378337
gene id: 244447:LOC103378337
uniprot id: A0A3P8WBY0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

244447:neurl2
gene id: 244447:neurl2
uniprot id: A0A3P8UKX1
names: Subcellular Location Annotation
messages: Cytoplasm

244447:ap3b2
gene id: 244447:ap3b2
uniprot id: A0A3P8UVF3
uniprot id: A0A3P8UWV0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adaptor complexes large subunit family.
messages: Subunit of non-clathrin- and clathrin-associated adaptor protein complex 3 (AP-3) that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. AP-3 appears to be involved in the sorting of a subset of transmembrane proteins targeted to lysosomes and lysosome-related organelles. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals.
messages: clathrin-coated vesicle membrane

244447:LOC103388667
gene id: 244447:LOC103388667
uniprot id: A0A3P8VJM0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for thyrotropin-releasing hormone (TRH). Upon ligand binding, this G-protein-coupled receptor triggers activation of the phosphatidylinositol (IP3)-calcium-protein kinase C (PKC) pathway.

244447:LOC103390593
gene id: 244447:LOC103390593
uniprot id: A0A3P8UND5
names: Similarity
messages: Belongs to the GDNFR family.

244447:LOC103389142
gene id: 244447:LOC103389142
uniprot id: A0A3P8WQV4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Apical cell membrane
messages: Belongs to the ATPase alpha/beta chains family.
messages: Non-catalytic subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex. The V1 complex consists of three catalytic AB heterodimers that form a heterohexamer, three peripheral stalks each consisting of EG heterodimers, one central rotor including subunits D and F, and the regulatory subunits C and H. The proton translocation complex V0 consists of the proton transport subunit a, a ring of proteolipid subunits c9c'', rotary subunit d, subunits e and f, and the accessory subunits.

244447:dvl1
gene id: 244447:dvl1
uniprot id: A0A3P8WYP1
names: Similarity
messages: Belongs to the DSH family.

244447:pnpla4
gene id: 244447:pnpla4
uniprot id: A0A3P8W253
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

244447:LOC103392076
gene id: 244447:LOC103392076
uniprot id: A0A3P8VX12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

244447:cep57
gene id: 244447:cep57
uniprot id: A0A3P8WNV3
names: Similarity
messages: Belongs to the translokin family.

244447:rad23b
gene id: 244447:rad23b
uniprot id: A0A3P8WIT3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RAD23 family.
messages: Cytoplasm
messages: Multiubiquitin chain receptor involved in modulation of proteasomal degradation. Involved in nucleotide excision repair.
messages: Nucleus

244447:LOC103386393
gene id: 244447:LOC103386393
uniprot id: A0A3P8VUI7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TGF-beta family.
messages: Homodimeric or heterodimeric through association with alpha and beta subunits, linked by one or more disulfide bonds. Inhibins are heterodimers of one alpha and one beta subunit. Activins are homo- or heterodimers of beta subunits only.
messages: Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins.
messages: Secreted

244447:ak3
gene id: 244447:ak3
uniprot id: A0A3P8UK73
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family. AK3 subfamily.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon GTP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent GTP hydrolysis.
messages: Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities.
messages: Mitochondrion matrix
messages: Monomer.

244447:creg1
gene id: 244447:creg1
uniprot id: A0A3P8VDD0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CREG family.
messages: Secreted

244447:gins3
gene id: 244447:gins3
uniprot id: A0A3P8UFU6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GINS3/PSF3 family.
messages: Chromosome
messages: Component of the GINS complex.
messages: Nucleus
messages: The GINS complex plays an essential role in the initiation of DNA replication.

244447:LOC103392579
gene id: 244447:LOC103392579
uniprot id: A0A3P8X1W9
names: Subcellular Location Annotation
messages: Membrane

244447:ccny
gene id: 244447:ccny
uniprot id: A0A3P8VWM3
names: Similarity
messages: Belongs to the cyclin family. Cyclin AB subfamily.
messages: Belongs to the cyclin family. Cyclin Y subfamily.

244447:LOC103397442
gene id: 244447:LOC103397442
uniprot id: A0A3P8VL12
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.

244447:LOC103378748
gene id: 244447:LOC103378748
uniprot id: A0A3P8UI16
uniprot id: A0A3P8UQ79
names: Similarity
messages: Belongs to the nucleobindin family.

244447:bbs5
gene id: 244447:bbs5
uniprot id: A0A3P8W026
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BBS5 family.
messages: Membrane
messages: Required for ciliogenesis.
messages: centriolar satellite
messages: cilium membrane

244447:acadvl
gene id: 244447:acadvl
uniprot id: A0A3P8UH41
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

244447:b2m
gene id: 244447:b2m
uniprot id: C4PJS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta-2-microglobulin family.
messages: Secreted

244447:LOC103384251
gene id: 244447:LOC103384251
uniprot id: A0A3P8WBC5
names: Similarity
messages: Belongs to the calreticulin family.

244447:LOC103387763
gene id: 244447:LOC103387763
uniprot id: A0A3P8WPA7
names: Subcellular Location Annotation
messages: Nucleus

244447:LOC103381950
gene id: 244447:LOC103381950
uniprot id: A0A3P8WP43
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Vesicular transporter family.
messages: Membrane

244447:mrpl30
gene id: 244447:mrpl30
uniprot id: A0A3P8UTM0
names: Similarity
messages: Belongs to the universal ribosomal protein uL30 family.

244447:slc25a19
gene id: 244447:slc25a19
uniprot id: A0A3P8VZF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

244447:LOC103391655
gene id: 244447:LOC103391655
uniprot id: A0A3P8UYQ9
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

244447:rnf114
gene id: 244447:rnf114
uniprot id: A0A3P8X1J8
names: Subunit
messages: Interacts with XAF1, the interaction increases XAF1 stability and proapoptotic effects, and may regulate IFN signaling.

244447:spast
gene id: 244447:spast
uniprot id: A0A3P8VX81
names: Similarity
messages: Belongs to the AAA ATPase family.

244447:rprd1a
gene id: 244447:rprd1a
uniprot id: A0A3P8WJU2
names: Similarity
messages: Belongs to the UPF0400 (RTT103) family.

244447:LOC103380768
gene id: 244447:LOC103380768
uniprot id: A0A3P8WSD8
names: Similarity
messages: Belongs to the cytochrome P450 family.

244447:med23
gene id: 244447:med23
uniprot id: A0A3P8WTN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mediator complex subunit 23 family.
messages: Nucleus

244447:crkl
gene id: 244447:crkl
uniprot id: A0A3P8UYA4
names: Similarity
messages: Belongs to the CRK family.

244447:ing2
gene id: 244447:ing2
uniprot id: A0A3P8W820
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ING family.
messages: Component of an histone acetyltransferase complex.
messages: Component of an histone acetyltransferase complex. Interacts with H3K4me3 and to a lesser extent with H3K4me2.
messages: Nucleus
messages: The PHD-type zinc finger mediates the binding to H3K4me3.

244447:LOC103381403
gene id: 244447:LOC103381403
uniprot id: A0A3P8V3Q1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with GIRK2, GIRK3 or GIRK4 to form a G-protein activated heteromultimer pore-forming unit. The resulting inward current is much larger.
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family. KCNJ3 subfamily.
messages: Membrane
messages: This potassium channel is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. This receptor plays a crucial role in regulating the heartbeat.

244447:LOC103396674
gene id: 244447:LOC103396674
uniprot id: A0A3P8X0I4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

244447:rrp36
gene id: 244447:rrp36
uniprot id: A0A3P8UGJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with 90S and pre-40S pre-ribosomal particles.
messages: Belongs to the RRP36 family.
messages: Component of the 90S pre-ribosome involved in the maturation of rRNAs. Required for early cleavages of the pre-RNAs in the 40S ribosomal subunit maturation pathway.
messages: nucleolus

244447:ppil1
gene id: 244447:ppil1
uniprot id: A0A3P8UG82
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

244447:exoc8
gene id: 244447:exoc8
uniprot id: A0A3P8UP09
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EXO84 family.
messages: Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.
messages: growth cone
messages: perinuclear region

244447:cldn1
gene id: 244447:cldn1
uniprot id: A0A3P8WKP4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

244447:LOC103378281
gene id: 244447:LOC103378281
uniprot id: A0A3P8W852
names: Similarity
messages: Belongs to the TCAF family.

244447:LOC103383815
gene id: 244447:LOC103383815
uniprot id: A0A3P8VF26
uniprot id: A0A3P8VHY2
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Functions as a GTPase-activating protein for the small GTPases RHOA, RHOB, RHOC and CDC42, terminating their downstream signaling. This induces morphological changes and detachment through cytoskeletal reorganization, playing a critical role in biological processes such as cell migration and proliferation. Also functions in vivo as an activator of the phospholipase PLCD1. Active DLC1 increases cell migration velocity but reduces directionality.
messages: Interacts with EF1A1, facilitates EF1A1 distribution to the membrane periphery and ruffles upon growth factor stimulation and suppresses cell migration.
messages: Membrane
messages: focal adhesion

244447:nqo1
gene id: 244447:nqo1
uniprot id: A0A3P8VA25
names: Similarity
messages: Belongs to the NAD(P)H dehydrogenase (quinone) family.

244447:bud31
gene id: 244447:bud31
uniprot id: A0A3P8V3A3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BUD31 (G10) family.
messages: Nucleus

244447:gabarap
gene id: 244447:gabarap
uniprot id: A0A3P8UTA7
names: Similarity
messages: Belongs to the ATG8 family.

244447:LOC103392074
gene id: 244447:LOC103392074
uniprot id: A0A3P8VX00
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calsequestrin family.
messages: Calsequestrin is a high-capacity, moderate affinity, calcium-binding protein and thus acts as an internal calcium store in muscle.
messages: Sarcoplasmic reticulum lumen

244447:nodal
gene id: 244447:nodal
uniprot id: A0A3P8WPC1
names: Similarity
messages: Belongs to the TGF-beta family.

244447:agmat
gene id: 244447:agmat
uniprot id: A0A3P8WQI2
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.

244447:hnf4a
gene id: 244447:hnf4a
uniprot id: A0A3P8VPF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

244447:tmlhe
gene id: 244447:tmlhe
uniprot id: A0A3P8VXN9
names: Similarity
messages: Belongs to the gamma-BBH/TMLD family.

244447:tmem63b
gene id: 244447:tmem63b
uniprot id: A0A3P8VSM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSC1 (TC 1.A.17) family.
messages: Membrane

244447:eif5a
gene id: 244447:eif5a
uniprot id: A0A3P8UTC9
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eIF-5A family.
messages: Endoplasmic reticulum membrane
messages: eIF-5A seems to be the only eukaryotic protein to have a hypusine residue which is a post-translational modification of a lysine by the addition of a butylamino group.
messages: mRNA-binding protein involved in translation elongation. Has an important function at the level of mRNA turnover, probably acting downstream of decapping. Critical for the efficient synthesis of peptide bonds between consecutive proline residues. Can resolve ribosomal stalling caused by consecutive prolines during translation. Involved in actin dynamics and cell cycle progression, mRNA decay and probably in a pathway involved in stress response and maintenance of cell wall integrity. Functions as a regulator of apoptosis.

244447:LOC103384533
gene id: 244447:LOC103384533
uniprot id: A0A3P8UKQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

244447:LOC103383494
gene id: 244447:LOC103383494
uniprot id: A0A3P8UTT8
names: Similarity
messages: Belongs to the actin family.

244447:cpox
gene id: 244447:cpox
uniprot id: A0A3P8W4M7
names: Similarity
names: Subunit
messages: Belongs to the aerobic coproporphyrinogen-III oxidase family.
messages: Homodimer.

244447:mri1
gene id: 244447:mri1
uniprot id: A0A3P8VTW9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).
messages: Cytoplasm
messages: Nucleus

244447:hmgcr
gene id: 244447:hmgcr
uniprot id: A0A3P8VKB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HMG-CoA reductase family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Peroxisome membrane

244447:LOC103383814
gene id: 244447:LOC103383814
uniprot id: A0A3P8VIA4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CTL (choline transporter-like) family.
messages: Cell membrane
messages: Choline transporter.
messages: Membrane

244447:LOC103379602
gene id: 244447:LOC103379602
uniprot id: A0A3P8V4S4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

244447:xpc
gene id: 244447:xpc
uniprot id: A0A3P8VAI2
names: Similarity
messages: Belongs to the XPC family.

244447:LOC103394835
gene id: 244447:LOC103394835
uniprot id: A0A3P8W246
names: Similarity
messages: Belongs to the BTG family.

244447:KEH01 p06
gene id: 244447:KEH01_p06
uniprot id: C5H0G0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 3 family.
messages: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity of complex I.
messages: Mitochondrion membrane

244447:tnpo3
gene id: 244447:tnpo3
uniprot id: A0A3P8V3W5
names: Subcellular Location Annotation
messages: Cytoplasm

244447:LOC103379316
gene id: 244447:LOC103379316
uniprot id: A0A3P8VPT8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Cytochromes P450 are a group of heme-thiolate monooxygenases. They oxidize a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Microsome membrane

244447:LOC103390748
gene id: 244447:LOC103390748
uniprot id: A0A3P8UWC4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Catalyzes the exchange of ADP and ATP across the membrane.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Monomer.

244447:LOC103379076
gene id: 244447:LOC103379076
uniprot id: A0A3P8VZ74
names: Subcellular Location Annotation
messages: cytoskeleton

244447:LOC103390181
gene id: 244447:LOC103390181
uniprot id: A0A3P8WHX1
names: Similarity
messages: Belongs to the TGF-beta family.

244447:dhrs11
gene id: 244447:dhrs11
uniprot id: A0A3P8WF47
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

244447:tf
gene id: 244447:tf
uniprot id: L7NCQ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferrin family.
messages: Monomer.
messages: Secreted
messages: Transferrins are iron binding transport proteins which bind Fe(3+) ion in association with the binding of an anion, usually bicarbonate.

244447:LOC103393388
gene id: 244447:LOC103393388
uniprot id: A0A3P8UEJ9
names: Similarity
messages: Belongs to the MAX family.

244447:olfml2a
gene id: 244447:olfml2a
uniprot id: A0A3P8VKK1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

244447:lmod1
gene id: 244447:lmod1
uniprot id: A0A3P8WSQ7
names: Subcellular Location Annotation
messages: cytoskeleton
messages: sarcomere

244447:LOC103390683
gene id: 244447:LOC103390683
uniprot id: A0A3P8VAX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tyrosinase family.
messages: Melanosome membrane

244447:LOC103380153
gene id: 244447:LOC103380153
uniprot id: A0A3P8V155
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

244447:LOC103397849
gene id: 244447:LOC103397849
uniprot id: A0A3P8X1T3
names: Similarity
messages: Belongs to the NipSnap family.

244447:nudt21
gene id: 244447:nudt21
uniprot id: A0A3P8UNM0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Nudix hydrolase family. CPSF5 subfamily.
messages: Component of the cleavage factor Im (CFIm) complex that functions as an activator of the pre-mRNA 3'-end cleavage and polyadenylation processing required for the maturation of pre-mRNA into functional mRNAs. CFIm contributes to the recruitment of multiprotein complexes on specific sequences on the pre-mRNA 3'-end, so called cleavage and polyadenylation signals (pA signals). Most pre-mRNAs contain multiple pA signals, resulting in alternative cleavage and polyadenylation (APA) producing mRNAs with variable 3'-end formation. The CFIm complex acts as a key regulator of cleavage and polyadenylation site choice during APA through its binding to 5'-UGUA-3' elements localized in the 3'-untranslated region (UTR) for a huge number of pre-mRNAs.
messages: Cytoplasm
messages: Homodimer (via N- and C-terminus); binds RNA as homodimer. Component of the cleavage factor Im (CFIm) complex.
messages: Nucleus

244447:LOC103380524
gene id: 244447:LOC103380524
uniprot id: A0A3P8WCM8
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

244447:LOC103380081
gene id: 244447:LOC103380081
uniprot id: A0A3P8UVI0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: Mitochondrion
messages: The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein (GCSH) shuttles the methylamine group of glycine from the P protein (GLDC) to the T protein (GCST).
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

244447:trappc3
gene id: 244447:trappc3
uniprot id: A0A3P8W6I3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAPP small subunits family. BET3 subfamily.
messages: Endoplasmic reticulum
messages: Homodimer.
messages: May play a role in vesicular transport from endoplasmic reticulum to Golgi.
messages: cis-Golgi network

244447:atp23
gene id: 244447:atp23
uniprot id: A0A3P8WID8
names: Similarity
messages: Belongs to the peptidase M76 family.

244447:LOC103391552
gene id: 244447:LOC103391552
uniprot id: A0A3P8W8A8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

244447:LOC103391297
gene id: 244447:LOC103391297
uniprot id: A0A3P8WJA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

244447:uba1
gene id: 244447:uba1
uniprot id: A0A3P8WVP9
names: Similarity
messages: Belongs to the ubiquitin-activating E1 family.

244447:asxl2
gene id: 244447:asxl2
uniprot id: A0A3P8VA65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Asx family.
messages: Nucleus

244447:vps16
gene id: 244447:vps16
uniprot id: A0A3P8VME0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS16 family.
messages: Early endosome
messages: Late endosome membrane
messages: Lysosome membrane
messages: Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes.
messages: Vesicle

244447:LOC103394147
gene id: 244447:LOC103394147
uniprot id: A0A3P8W5U3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

244447:dgcr2
gene id: 244447:dgcr2
uniprot id: A0A3P8WF10
uniprot id: A0A3P8WHJ0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

244447:LOC103388161
gene id: 244447:LOC103388161
uniprot id: A0A3P8V344
names: Similarity
messages: Belongs to the peptidase C19 family.

244447:LOC103392729
gene id: 244447:LOC103392729
uniprot id: A0A3P8VPH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Membrane
messages: cis-Golgi network membrane

244447:pkp3
gene id: 244447:pkp3
uniprot id: A0A3P8V3D4
names: Similarity
messages: Belongs to the beta-catenin family.

244447:ptgfr
gene id: 244447:ptgfr
uniprot id: A0A3P8X0N0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

244447:fut9
gene id: 244447:fut9
uniprot id: A0A3P8URA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 10 family.
messages: Golgi stack membrane

244447:ctsh
gene id: 244447:ctsh
uniprot id: A0A3P8W3R1
names: Similarity
messages: Belongs to the peptidase C1 family.

244447:trub1
gene id: 244447:trub1
uniprot id: A0A3P8VYT6
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family.

244447:ccnj
gene id: 244447:ccnj
uniprot id: A0A3P8VF84
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cyclin family. Cyclin AB subfamily.
messages: Essential for the control of the cell cycle at the G2/M (mitosis) transition.
messages: Interacts with the CDK1 protein kinase to form a serine/threonine kinase holoenzyme complex also known as maturation promoting factor (MPF). The cyclin subunit imparts substrate specificity to the complex.

244447:galnt7
gene id: 244447:galnt7
uniprot id: A0A3P8WCS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

244447:LOC103389036
gene id: 244447:LOC103389036
uniprot id: A0A3P8WAK0
uniprot id: A0A3P8WIP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAGUK family.
messages: Cell membrane
messages: Membrane
messages: tight junction

244447:ctbs
gene id: 244447:ctbs
uniprot id: A0A3P8VJ76
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family.

244447:cpd
gene id: 244447:cpd
uniprot id: A0A3P8VHL7
names: Similarity
messages: Belongs to the peptidase M14 family.

244447:necap2
gene id: 244447:necap2
uniprot id: A0A3P8UQN7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NECAP family.
messages: Involved in endocytosis.
messages: clathrin-coated vesicle membrane

244447:gper1
gene id: 244447:gper1
uniprot id: A0A3P8VPJ0
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

244447:sox9
gene id: 244447:sox9
uniprot id: A0A3P8WED3
uniprot id: E3SC19
names: Subcellular Location Annotation
messages: Nucleus

244447:nlk
gene id: 244447:nlk
uniprot id: A0A3P8UVM5
names: Activity Regulation
names: Similarity
messages: Activated by threonine and tyrosine phosphorylation.
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.

244447:LOC103385593
gene id: 244447:LOC103385593
uniprot id: A0A3P8X420
names: Similarity
messages: Belongs to the TPD52 family.

244447:LOC103397178
gene id: 244447:LOC103397178
uniprot id: A0A3P8W083
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

244447:LOC103395179
gene id: 244447:LOC103395179
uniprot id: A0A3P8VRY7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

244447:podxl2
gene id: 244447:podxl2
uniprot id: A0A3P8WEI7
names: Subcellular Location Annotation
messages: Membrane

244447:prrx1
gene id: 244447:prrx1
uniprot id: A0A3P8UM63
uniprot id: A0A3P8UNB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paired homeobox family.
messages: Nucleus

244447:nploc4
gene id: 244447:nploc4
uniprot id: A0A3P8UQ48
names: Similarity
messages: Belongs to the NPL4 family.

244447:hdhd2
gene id: 244447:hdhd2
uniprot id: A0A3P8WX46
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

244447:LOC103385124
gene id: 244447:LOC103385124
uniprot id: A0A3P8VCE9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

244447:LOC103377494
gene id: 244447:LOC103377494
uniprot id: A0A3P8UP93
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane
messages: Membrane

244447:LOC103382008
gene id: 244447:LOC103382008
uniprot id: A0A3P8WUF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the carnitine/choline acetyltransferase family.
messages: Membrane
messages: Mitochondrion outer membrane

244447:nid1
gene id: 244447:nid1
uniprot id: A0A3P8W4J0
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: basement membrane

244447:cbl
gene id: 244447:cbl
uniprot id: A0A3P8WLK8
names: Domain
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: E3 ubiquitin-protein ligase which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, and transfers it to substrates, generally promoting their degradation by the proteasome.
messages: The N-terminus is composed of the phosphotyrosine binding (PTB) domain, a short linker region and the RING-type zinc finger. The PTB domain, which is also called TKB (tyrosine kinase binding) domain, is composed of three different subdomains: a four-helix bundle (4H), a calcium-binding EF hand and a divergent SH2 domain.

244447:LOC107988649
gene id: 244447:LOC107988649
uniprot id: A0A3Q9HIV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the spexin family.
messages: Secreted

244447:LOC103383382
gene id: 244447:LOC103383382
uniprot id: A0A3P8UGX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IRF2BP family.
messages: Nucleus

244447:rxra
gene id: 244447:rxra
uniprot id: A0A3P8UXU5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nuclear hormone receptor family. NR2 subfamily.
messages: Composed of three domains: a modulating N-terminal domain, a DNA-binding domain and a C-terminal ligand-binding domain.
messages: Homodimer. Heterodimer; with a rar molecule.
messages: Nucleus
messages: Receptor for retinoic acid that acts as a transcription factor. Forms homo- or heterodimers with retinoic acid receptors (rars) and binds to target response elements in response to their ligands, all-trans or 9-cis retinoic acid, to regulate gene expression in various biological processes.

244447:LOC103384837
gene id: 244447:LOC103384837
uniprot id: A0A3P8UHC4
names: Similarity
messages: Belongs to the MARCKS family.

244447:LOC103389952
gene id: 244447:LOC103389952
uniprot id: A0A3P8VVU8
names: Similarity
messages: Belongs to the PtdIns transfer protein family. PI transfer class IIA subfamily.

244447:mrpl27
gene id: 244447:mrpl27
uniprot id: A0A3P8UPV6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

244447:ezh1
gene id: 244447:ezh1
uniprot id: A0A3P8WLD4
names: Subcellular Location Annotation
messages: Nucleus

244447:coq6
gene id: 244447:coq6
uniprot id: A0A3P8UIP3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UbiH/COQ6 family.
messages: Cell projection
messages: Component of a multi-subunit COQ enzyme complex, composed of at least COQ3, COQ4, COQ5, COQ6, COQ7 and COQ9. Interacts with ADCK4 and COQ7.
messages: FAD-dependent monooxygenase required for the C5-ring hydroxylation during ubiquinone biosynthesis. Catalyzes the hydroxylation of 3-polyprenyl-4-hydroxybenzoic acid to 3-polyprenyl-4,5-dihydroxybenzoic acid. The electrons required for the hydroxylation reaction may be funneled indirectly from NADPH via a ferredoxin/ferredoxin reductase system to COQ6.
messages: Golgi apparatus
messages: Mitochondrion inner membrane

244447:foxl2
gene id: 244447:foxl2
uniprot id: E3SC20
names: Subcellular Location Annotation
messages: Nucleus

244447:amdhd1
gene id: 244447:amdhd1
uniprot id: A0A3P8UXQ2
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. HutI family.

244447:LOC103391308
gene id: 244447:LOC103391308
uniprot id: A0A3P8WT33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAF1 family.
messages: Nucleus

244447:lonp2
gene id: 244447:lonp2
uniprot id: A0A3P8W6B6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: ATP-dependent serine protease that mediates the selective degradation of misfolded and unassembled polypeptides in the peroxisomal matrix. Necessary for type 2 peroxisome targeting signal (PTS2)-containing protein processing and facilitates peroxisome matrix protein import.
messages: Belongs to the peptidase S16 family.
messages: Peroxisome matrix

244447:LOC103389268
gene id: 244447:LOC103389268
uniprot id: A0A3P8UKH5
names: Similarity
messages: Belongs to the cyclin family. Cyclin AB subfamily.

244447:LOC103394382
gene id: 244447:LOC103394382
uniprot id: A0A3P8WI59
names: Function
names: Similarity
messages: Belongs to the RutC family.
messages: Catalyzes the hydrolytic deamination of enamine/imine intermediates that form during the course of normal metabolism. May facilitate the release of ammonia from these potentially toxic reactive metabolites, reducing their impact on cellular components. It may act on enamine/imine intermediates formed by several types of pyridoxal-5'-phosphate-dependent dehydratases including L-threonine dehydratase.

244447:LOC103388880
gene id: 244447:LOC103388880
uniprot id: A0A3P8W131
names: Similarity
messages: Belongs to the syntaxin family.

244447:ankh
gene id: 244447:ankh
uniprot id: A0A3P8X2B9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ANKH family.
messages: Membrane
messages: Regulates intra- and extracellular levels of inorganic pyrophosphate (PPi), probably functioning as PPi transporter.

244447:LOC103398228
gene id: 244447:LOC103398228
uniprot id: A0A3P8W8K2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the stanniocalcin family.
messages: Homodimer; disulfide-linked.
messages: Its primary function is the prevention of hypercalcemia. Upon release into the circulation, it lowers calcium transport by the gills, thereby reducing its rate of influx from the environment into the extracellular compartment. STC also stimulates phosphate reabsorption by renal proximal tubules. The consequence of this action is increased levels of plasma phosphate, which combines with excess calcium and promotes its disposal into bone and scales.

244447:mpdu1
gene id: 244447:mpdu1
uniprot id: A0A3P8WC14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MPDU1 (TC 2.A.43.3) family.
messages: Membrane

244447:rpl31
gene id: 244447:rpl31
uniprot id: A0A3P8VNL3
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL31 family.
messages: Component of the large ribosomal subunit.

244447:LOC103397076
gene id: 244447:LOC103397076
uniprot id: A0A3P8WW89
names: Subcellular Location Annotation
messages: Membrane

244447:LOC103386709
gene id: 244447:LOC103386709
uniprot id: A0A3P8WWA4
names: Subcellular Location Annotation
messages: extracellular space

244447:LOC103395858
gene id: 244447:LOC103395858
uniprot id: A0A3P8VW16
uniprot id: A0A3P8VW56
names: Similarity
messages: Belongs to the JHDM3 histone demethylase family.

244447:xk
gene id: 244447:xk
uniprot id: A0A3P8USJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XK family.
messages: Membrane

244447:LOC103389871
gene id: 244447:LOC103389871
uniprot id: A0A3P8VM69
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAR3 family.
messages: Cell junction
messages: Endomembrane system

244447:emc3
gene id: 244447:emc3
uniprot id: A0A3P8ULN3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EMC3 family.
messages: Component of the ER membrane protein complex (EMC).
messages: Membrane

244447:emc10
gene id: 244447:emc10
uniprot id: A0A3P8VV54
uniprot id: A0A3P8W3I8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EMC10 family.
messages: Component of the ER membrane protein complex (EMC).
messages: Membrane

244447:LOC103394811
gene id: 244447:LOC103394811
uniprot id: A0A3P8VYB2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 43 family.
messages: Golgi apparatus membrane
messages: Membrane

244447:LOC103377182
gene id: 244447:LOC103377182
uniprot id: A0A3P8WBG9
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eIF-5A family.
messages: Endoplasmic reticulum membrane
messages: eIF-5A seems to be the only eukaryotic protein to have a hypusine residue which is a post-translational modification of a lysine by the addition of a butylamino group.
messages: mRNA-binding protein involved in translation elongation. Has an important function at the level of mRNA turnover, probably acting downstream of decapping. Critical for the efficient synthesis of peptide bonds between consecutive proline residues. Can resolve ribosomal stalling caused by consecutive prolines during translation. Involved in actin dynamics and cell cycle progression, mRNA decay and probably in a pathway involved in stress response and maintenance of cell wall integrity. Functions as a regulator of apoptosis.

244447:pitrm1
gene id: 244447:pitrm1
uniprot id: A0A3P8X563
names: Subunit
messages: Monomer and homodimer; homodimerization is induced by binding of the substrate.

244447:LOC103390640
gene id: 244447:LOC103390640
uniprot id: A0A3P8UXD9
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

244447:LOC103391347
gene id: 244447:LOC103391347
uniprot id: A0A3P8WPB7
names: Similarity
messages: Belongs to the dapper family.

244447:sf3b5
gene id: 244447:sf3b5
uniprot id: A0A3P8UW55
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SF3B5 family.
messages: Component of the spliceosome B complex.
messages: Nucleus

244447:sgsm3
gene id: 244447:sgsm3
uniprot id: A0A3P8W183
names: Similarity
messages: Belongs to the small G protein signaling modulator family.

244447:rnf34
gene id: 244447:rnf34
uniprot id: A0A3P8WLG9
names: Subcellular Location Annotation
messages: Cell membrane

244447:LOC103383782
gene id: 244447:LOC103383782
uniprot id: A0A3P8VGZ5
names: Similarity
messages: Belongs to the DEAD box helicase family.

244447:LOC103388194
gene id: 244447:LOC103388194
uniprot id: A0A3P8UHW1
names: Subcellular Location Annotation
messages: Nucleus

244447:copb1
gene id: 244447:copb1
uniprot id: A0A3P8VMZ3
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: COPI-coated vesicle membrane
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Membrane
messages: Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.
messages: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.

244447:pou4f2
gene id: 244447:pou4f2
uniprot id: A0A3P8UJY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POU transcription factor family.
messages: Nucleus

244447:ezr
gene id: 244447:ezr
uniprot id: A0A3P8X0T3
names: Subcellular Location Annotation
messages: Membrane
messages: cytoskeleton

244447:inpp4a
gene id: 244447:inpp4a
uniprot id: A0A3P8UWA5
uniprot id: A0A3P8UXU4
names: Similarity
messages: Belongs to the inositol 3,4-bisphosphate 4-phosphatase family.

244447:LOC103397870
gene id: 244447:LOC103397870
uniprot id: A0A3P8X4N3
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

244447:LOC103393660
gene id: 244447:LOC103393660
uniprot id: A0A3P8WJL1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELOF1 family.
messages: Nucleus
messages: Transcription elongation factor implicated in the maintenance of proper chromatin structure in actively transcribed regions.

244447:ifrd2
gene id: 244447:ifrd2
uniprot id: A0A3P8V0N0
uniprot id: A0A3P8V303
names: Similarity
messages: Belongs to the IFRD family.

244447:tomm40
gene id: 244447:tomm40
uniprot id: A0A3P8VQB7
uniprot id: A0A3P8VSN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tom40 family.
messages: Membrane
messages: Mitochondrion outer membrane

244447:kcnh6
gene id: 244447:kcnh6
uniprot id: A0A3P8X6T9
names: Subcellular Location Annotation
messages: Membrane

244447:LOC103388427
gene id: 244447:LOC103388427
uniprot id: A0A3P8V4U8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

244447:pcnx4
gene id: 244447:pcnx4
uniprot id: A0A3P8UIL5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pecanex family.
messages: Membrane

244447:ada
gene id: 244447:ada
uniprot id: A0A3P8VLI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.
messages: Cell junction
messages: Cell membrane
messages: Cytoplasmic vesicle lumen

244447:LOC103389096
gene id: 244447:LOC103389096
uniprot id: A0A3P8WJK8
names: Similarity
messages: Belongs to the histone H3 family.

244447:LOC103392309
gene id: 244447:LOC103392309
uniprot id: A0A3P8WB78
names: Similarity
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.

244447:LOC103377770
gene id: 244447:LOC103377770
uniprot id: A0A3P8V2Q6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCG family. Eye pigment precursor importer (TC 3.A.1.204) subfamily.
messages: Membrane

244447:LOC103397625
gene id: 244447:LOC103397625
uniprot id: A0A3P8WRX0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CRF-binding protein family.
messages: Binds CRF and inactivates it. May prevent inappropriate pituitary-adrenal stimulation in pregnancy.
messages: Secreted

244447:scn1b
gene id: 244447:scn1b
uniprot id: A0A3P8VI91
names: Subcellular Location Annotation
messages: Membrane

244447:sppl2b
gene id: 244447:sppl2b
uniprot id: A0A3P8WDH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A22B family.
messages: Endosome membrane
messages: Lysosome membrane
messages: Membrane

244447:cap2
gene id: 244447:cap2
uniprot id: A0A3P8WN05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAP family.
messages: Cell membrane

244447:incenp
gene id: 244447:incenp
uniprot id: A0A3P8VCV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the INCENP family.
messages: Nucleus
messages: spindle

244447:nup35
gene id: 244447:nup35
uniprot id: A0A3P8UL40
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Nup35 family.
messages: Functions as a component of the nuclear pore complex (NPC).
messages: nuclear pore complex

244447:eif4h
gene id: 244447:eif4h
uniprot id: A0A3P8WIJ2
names: Function
names: Subcellular Location Annotation
messages: Stimulates the RNA helicase activity of EIF4A in the translation initiation complex. Binds weakly mRNA.
messages: perinuclear region

244447:stx7
gene id: 244447:stx7
uniprot id: A0A3P8WUE8
names: Similarity
messages: Belongs to the syntaxin family.

244447:lzic
gene id: 244447:lzic
uniprot id: A0A3P8VBN4
names: Similarity
messages: Belongs to the CTNNBIP1 family.

244447:LOC103395203
gene id: 244447:LOC103395203
uniprot id: A0A3P8VXR1
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.

244447:LOC103388245
gene id: 244447:LOC103388245
uniprot id: A0A3P8UPK1
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

244447:LOC103397462
gene id: 244447:LOC103397462
uniprot id: A0A3P8VQ34
names: Similarity
messages: Belongs to the intermediate filament family.

244447:stk40
gene id: 244447:stk40
uniprot id: A0A3P8WY39
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: May be a negative regulator of NF-kappa-B and p53-mediated gene transcription.
messages: Nucleus

244447:gosr1
gene id: 244447:gosr1
uniprot id: A0A3P8V989
uniprot id: A0A3P8VF75
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GOSR1 family.
messages: Component of several multiprotein Golgi SNARE complexes.
messages: Golgi apparatus membrane
messages: Involved in transport from the ER to the Golgi apparatus as well as in intra-Golgi transport. It belongs to a super-family of proteins called t-SNAREs or soluble NSF (N-ethylmaleimide-sensitive factor) attachment protein receptor. May play a protective role against hydrogen peroxide induced cytotoxicity under glutathione depleted conditions in neuronal cells by regulating the intracellular ROS levels via inhibition of p38 MAPK (MAPK11, MAPK12, MAPK13 and MAPK14). Participates in docking and fusion stage of ER to cis-Golgi transport. Plays an important physiological role in VLDL-transport vesicle-Golgi fusion and thus in VLDL delivery to the hepatic cis-Golgi.
messages: Membrane

244447:LOC103378577
gene id: 244447:LOC103378577
uniprot id: A0A3P8WRX4
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.

244447:eif4a1
gene id: 244447:eif4a1
uniprot id: A0A3P8WF55
names: Similarity
messages: Belongs to the DEAD box helicase family. eIF4A subfamily.

244447:lzts2
gene id: 244447:lzts2
uniprot id: A0A3P8VV03
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LZTS2 family.
messages: Cytoplasm
messages: Negative regulator of katanin-mediated microtubule severing and release from the centrosome. Required for central spindle formation and the completion of cytokinesis. Negative regulator of the Wnt signaling pathway. Represses beta-catenin-mediated transcriptional activation by promoting the nuclear exclusion of beta-catenin.
messages: centrosome

244447:LOC103395057
gene id: 244447:LOC103395057
uniprot id: A0A3P8WZ09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family.
messages: Membrane

244447:LOC103396513
gene id: 244447:LOC103396513
uniprot id: A0A3P8WH38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Membrane

244447:acp5
gene id: 244447:acp5
uniprot id: A0A3P8W9R7
names: Cofactor
messages: Binds 2 iron ions per subunit.

244447:slc10a2
gene id: 244447:slc10a2
uniprot id: A0A3P8WF36
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bile acid:sodium symporter (BASS) (TC 2.A.28) family.
messages: Membrane
messages: Monomer and homodimer.

244447:cdk2ap1
gene id: 244447:cdk2ap1
uniprot id: A0A3P8VW78
names: Similarity
messages: Belongs to the CDK2AP family.

244447:fuca1
gene id: 244447:fuca1
uniprot id: A0A3P8W752
names: Function
names: Similarity
names: Subunit
messages: Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins.
messages: Belongs to the glycosyl hydrolase 29 family.
messages: Homotetramer.

244447:LOC103391834
gene id: 244447:LOC103391834
uniprot id: A0A3P8V2V3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

244447:ywhae
gene id: 244447:ywhae
uniprot id: A0A3P8V0V6
names: Similarity
names: Subunit
messages: Belongs to the 14-3-3 family.
messages: Homodimer, and heterodimer with other family members.

244447:LOC103381528
gene id: 244447:LOC103381528
uniprot id: A0A3P8VEC6
uniprot id: A0A3P8VMH0
names: Similarity
messages: Belongs to the synuclein family.

244447:smc1a
gene id: 244447:smc1a
uniprot id: A0A3P8UNS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMC family. SMC1 subfamily.
messages: Chromosome
messages: Nucleus

244447:pex10
gene id: 244447:pex10
uniprot id: A0A3P8UY79
names: Function
names: Similarity
messages: Belongs to the pex2/pex10/pex12 family.
messages: Somewhat implicated in the biogenesis of peroxisomes.

244447:LOC103391298
gene id: 244447:LOC103391298
uniprot id: A0A3P8WM00
names: Similarity
messages: Belongs to the peptidase C1 family.

244447:LOC103396063
gene id: 244447:LOC103396063
uniprot id: A0A3P8WH60
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELO family. ELOVL1 subfamily.
messages: Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that exhibits activity toward saturated C18 to C26 acyl-CoA substrates, with the highest activity towards C22:0 acyl-CoA. May participate to the production of both saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: The C-terminal di-lysine motif may confer endoplasmic reticulum localization.

244447:LOC103398283
gene id: 244447:LOC103398283
uniprot id: A0A3P8WHN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Homer family.
messages: Cytoplasm
messages: Postsynaptic density
messages: Synapse

244447:LOC103397246
gene id: 244447:LOC103397246
uniprot id: A0A3P8WCI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the patched family.
messages: Membrane

244447:aga
gene id: 244447:aga
uniprot id: A0A3P8V0A1
names: Similarity
messages: Belongs to the Ntn-hydrolase family.

244447:ndufa3
gene id: 244447:ndufa3
uniprot id: A0A3P8UT09
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFA3 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Membrane
messages: Mitochondrion inner membrane

244447:LOC103383468
gene id: 244447:LOC103383468
uniprot id: A0A3P8UMD6
uniprot id: A0A3P8URY3
names: Similarity
messages: Belongs to the OSBP family.

244447:gal3st1
gene id: 244447:gal3st1
uniprot id: A0A3P8WLC1
names: Similarity
messages: Belongs to the galactose-3-O-sulfotransferase family.

244447:mvd
gene id: 244447:mvd
uniprot id: A0A3P8VCX6
names: Function
names: Similarity
messages: Belongs to the diphosphomevalonate decarboxylase family.
messages: Catalyzes the ATP dependent decarboxylation of (R)-5-diphosphomevalonate to form isopentenyl diphosphate (IPP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoids and sterol synthesis.

244447:atp5f1d
gene id: 244447:atp5f1d
uniprot id: A0A3P8UV29
names: Similarity
messages: Belongs to the ATPase epsilon chain family.

244447:ildr2
gene id: 244447:ildr2
uniprot id: A0A3P8V1I8
uniprot id: A0A3P8V1J3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. LISCH7 family.
messages: Membrane
messages: tight junction

244447:rps5
gene id: 244447:rps5
uniprot id: A0A3P8VQ66
names: Similarity
messages: Belongs to the universal ribosomal protein uS7 family.

244447:col4a3bp
gene id: 244447:col4a3bp
uniprot id: A0A3P8VT59
uniprot id: A0A3P8VVL2
names: Subcellular Location Annotation
messages: Endoplasmic reticulum
messages: Golgi apparatus

244447:tmem150a
gene id: 244447:tmem150a
uniprot id: A0A3P8VSW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DRAM/TMEM150 family.
messages: Cell membrane
messages: Membrane

244447:ddx52
gene id: 244447:ddx52
uniprot id: A0A3P8VQL5
names: Similarity
messages: Belongs to the DEAD box helicase family. DDX52/ROK1 subfamily.

244447:LOC103383989
gene id: 244447:LOC103383989
uniprot id: A0A3P8VLH4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C54 family.
messages: Cysteine protease that plays a key role in autophagy by mediating both proteolytic activation and delipidation of ATG8 family proteins.
messages: Cytoplasm

244447:LOC103384504
gene id: 244447:LOC103384504
uniprot id: A0A3P8X1E8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family.
messages: Monomer. Homodimer; disulfide-linked.
messages: Secreted
messages: The N- and C-terminal barrels adopt an identical fold despite having only 13% of conserved residues.
messages: The N-terminal region may be exposed to the interior of the granule, whereas the C-terminal portion may be embedded in the membrane. During phagocytosis and degranulation, proteases may be released and activated and cleave BPI at the junction of the N- and C-terminal portions of the molecule, providing controlled release of the N-terminal antibacterial fragment when bacteria are ingested.
messages: The cytotoxic action of BPI is limited to many species of Gram-negative bacteria; this specificity may be explained by a strong affinity of the very basic N-terminal half for the negatively charged lipopolysaccharides that are unique to the Gram-negative bacterial outer envelope.

244447:mrpl44
gene id: 244447:mrpl44
uniprot id: A0A3P8UP00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ribonuclease III family. Mitochondrion-specific ribosomal protein mL44 subfamily.
messages: Mitochondrion

244447:LOC103378371
gene id: 244447:LOC103378371
uniprot id: A0A3P8USA3
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

244447:LOC103395215
gene id: 244447:LOC103395215
uniprot id: A0A3P8VX27
uniprot id: A0A3P8VX38
names: Subcellular Location Annotation
messages: Membrane

244447:fam234a
gene id: 244447:fam234a
uniprot id: A0A3P8WNY0
names: Similarity
messages: Belongs to the FAM234 family.

244447:LOC103398162
gene id: 244447:LOC103398162
uniprot id: A0A3P8W2S4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TGF-beta family. GDNF subfamily.
messages: Secreted

244447:LOC103388818
gene id: 244447:LOC103388818
uniprot id: A0A3P8VWA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

244447:htra1
gene id: 244447:htra1
uniprot id: A0A3P8UTD7
names: Similarity
messages: Belongs to the peptidase S1C family.

244447:six6
gene id: 244447:six6
uniprot id: A0A3P8UPR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SIX/Sine oculis homeobox family.
messages: Nucleus

244447:alad
gene id: 244447:alad
uniprot id: A0A3P8WCD4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen.
messages: Homooctamer; active form. Homohexamer; low activity form.

244447:igf2bp2
gene id: 244447:igf2bp2
uniprot id: A0A3P8VVC2
names: Similarity
messages: Belongs to the RRM IMP/VICKZ family.

244447:narfl
gene id: 244447:narfl
uniprot id: A0A3P8WJH7
names: Similarity
messages: Belongs to the NARF family.

244447:ipo9
gene id: 244447:ipo9
uniprot id: A0A3P8WVF7
names: Subcellular Location Annotation
messages: Cytoplasm

244447:LOC103396276
gene id: 244447:LOC103396276
uniprot id: A0A3P8WRC0
uniprot id: A0A3P8WRJ3
uniprot id: A0A3P8WTH8
uniprot id: A0A3P8WTI9
names: Similarity
messages: Belongs to the MAGUK family.

244447:manba
gene id: 244447:manba
uniprot id: A0A3P8VW64
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycosyl hydrolase 2 family.
messages: Exoglycosidase that cleaves the single beta-linked mannose residue from the non-reducing end of all N-linked glycoprotein oligosaccharides.
messages: Lysosome
messages: Monomer.

244447:ube2h
gene id: 244447:ube2h
uniprot id: A0A3P8VGL8
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

244447:LOC103384843
gene id: 244447:LOC103384843
uniprot id: A0A3P8UZH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paired homeobox family.
messages: Nucleus

244447:LOC103397434
gene id: 244447:LOC103397434
uniprot id: A0A3P8VP19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PPP phosphatase family. PP-1 subfamily.
messages: Cleavage furrow
messages: Cytoplasm
messages: Midbody

244447:pemt
gene id: 244447:pemt
uniprot id: A0A3P8X1N3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class VI-like SAM-binding methyltransferase superfamily. PEMT/PEM2 methyltransferase family.
messages: Catalyzes the three sequential steps of the methylation pathway for the biosynthesis of phosphatidylcholine, a critical and essential component for membrane structure. Uses S-adenosylmethionine (S-adenosyl-L-methionine, SAM or AdoMet) as the methyl group donor for the methylation of phosphatidylethanolamine (1,2-diacyl-sn-glycero-3-phosphoethanolamine, PE) to phosphatidylmonomethylethanolamine (1,2-diacyl-sn-glycero-3-phospho-N-methylethanolamine, PMME), PMME to phosphatidyldimethylethanolamine (1,2-diacyl-sn-glycero-3-phospho-N,N-dimethylethanolamine, PDME), and PDME to phosphatidylcholine (1,2-diacyl-sn-glycero-3-phosphocholine, PC), producing S-adenosyl-L-homocysteine in each step.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Mitochondrion membrane

244447:acap1
gene id: 244447:acap1
uniprot id: A0A3P8ULN0
names: Activity Regulation
names: Domain
names: Function
names: Subcellular Location Annotation
messages: Endosome membrane
messages: GAP activity stimulated by phosphatidylinositol 4,5-bisphosphate (PIP2) and phosphatidic acid.
messages: GTPase-activating protein for the ADP ribosylation factor family.
messages: PH domain binds phospholipids including phosphatidic acid, phosphatidylinositol 3-phosphate, phosphatidylinositol 3,5-bisphosphate (PIP2) and phosphatidylinositol 3,4,5-trisphosphate (PIP3). May mediate protein binding to PIP2 or PIP3 containing membranes.
messages: The BAR domain mediates homodimerization, it can neither bind membrane nor impart curvature, but instead requires the neighboring PH domain to achieve these functions.

244447:LOC103387207
gene id: 244447:LOC103387207
uniprot id: A0A3P8V445
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily.
messages: dendrite

244447:scg5
gene id: 244447:scg5
uniprot id: A0A3P8UZ86
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 7B2 family.
messages: Secreted

244447:pigl
gene id: 244447:pigl
uniprot id: A0A3P8WEM5
names: Function
names: Similarity
messages: Belongs to the PIGL family.
messages: Involved in the second step of GPI biosynthesis. De-N-acetylation of N-acetylglucosaminyl-phosphatidylinositol.

244447:LOC103392531
gene id: 244447:LOC103392531
uniprot id: A0A3P8X4N8
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: RNA-binding protein that regulates alternative splicing events.

244447:lrrn3
gene id: 244447:lrrn3
uniprot id: A0A3P8VYW0
names: Subcellular Location Annotation
messages: Membrane

244447:fgf16
gene id: 244447:fgf16
uniprot id: A0A3P8WFT9
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

244447:endog
gene id: 244447:endog
uniprot id: A0A3P8VE18
names: Similarity
messages: Belongs to the DNA/RNA non-specific endonuclease family.

244447:LOC103399879
gene id: 244447:LOC103399879
uniprot id: A0A3P8UU40
names: Similarity
messages: Belongs to the glutathione peroxidase family.

244447:hibch
gene id: 244447:hibch
uniprot id: A0A3P8WFX3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: Hydrolyzes 3-hydroxyisobutyryl-CoA (HIBYL-CoA), a saline catabolite. Has high activity toward isobutyryl-CoA. Could be an isobutyryl-CoA dehydrogenase that functions in valine catabolism. Also hydrolyzes 3-hydroxypropanoyl-CoA.
messages: Mitochondrion

244447:ilk
gene id: 244447:ilk
uniprot id: A0A3P8VDY5
names: Subcellular Location Annotation
messages: focal adhesion
messages: lamellipodium
messages: sarcomere

244447:LOC103386239
gene id: 244447:LOC103386239
uniprot id: A0A3P8VD21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

244447:mars2
gene id: 244447:mars2
uniprot id: A0A3P8UVY9
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

244447:LOC103395874
gene id: 244447:LOC103395874
uniprot id: A0A3P8VY19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TORC family.
messages: Cytoplasm
messages: Nucleus

244447:aars
gene id: 244447:aars
uniprot id: A0A3P8W9S7
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Alax-L subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Monomer. Interacts with ANKRD16; the interaction is direct.

244447:LOC103388825
gene id: 244447:LOC103388825
uniprot id: A0A3P8VWE4
names: Similarity
messages: Belongs to the MS4A family.

244447:LOC103393606
gene id: 244447:LOC103393606
uniprot id: A0A3P8W386
names: Similarity
messages: Belongs to the proteasome subunit S9 family.

244447:LOC103381863
gene id: 244447:LOC103381863
uniprot id: A0A3P8WFE8
names: Similarity
names: Subunit
messages: Belongs to the cyclin-dependent kinase 5 activator family.
messages: Heterodimer of a catalytic subunit and a regulatory subunit.

244447:LOC103396588
gene id: 244447:LOC103396588
uniprot id: A0A3P8X5X2
names: Similarity
messages: Belongs to the peptidase M10A family.

244447:LOC103390458
gene id: 244447:LOC103390458
uniprot id: A0A3P8UK06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Orai family.
messages: Membrane

244447:gys2
gene id: 244447:gys2
uniprot id: A0A3P8WE78
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 3 family.
messages: Transfers the glycosyl residue from UDP-Glc to the non-reducing end of alpha-1,4-glucan.

244447:ctsc
gene id: 244447:ctsc
uniprot id: A0A3P8WQY5
names: Similarity
names: Subunit
messages: Belongs to the peptidase C1 family.
messages: Tetramer of heterotrimers consisting of exclusion domain, heavy- and light chains.

244447:fam19a5
gene id: 244447:fam19a5
uniprot id: A0A3P8VXX0
names: Similarity
messages: Belongs to the TAFA family.

244447:ghitm
gene id: 244447:ghitm
uniprot id: A0A3P8WRE3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

244447:LOC103381880
gene id: 244447:LOC103381880
uniprot id: A0A3P8WEH6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

244447:LOC103379120
gene id: 244447:LOC103379120
uniprot id: A0A3P8W5A6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase T2 family.
messages: Lysosome lumen

244447:anapc11
gene id: 244447:anapc11
uniprot id: A0A3P8WHR4
names: Similarity
messages: Belongs to the RING-box family.

244447:ssr1
gene id: 244447:ssr1
uniprot id: A0A3P8WJ00
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP-alpha family.
messages: Endoplasmic reticulum membrane
messages: Heterotetramer of TRAP-alpha, TRAP-beta, TRAP-delta and TRAP-gamma.
messages: Membrane
messages: Shows a remarkable charge distribution with the N-terminus being highly negatively charged, and the cytoplasmic C-terminus positively charged.
messages: TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins. May be involved in the recycling of the translocation apparatus after completion of the translocation process or may function as a membrane-bound chaperone facilitating folding of translocated proteins.

244447:dnttip1
gene id: 244447:dnttip1
uniprot id: A0A3P8X234
names: Subcellular Location Annotation
messages: Nucleus

244447:myoc
gene id: 244447:myoc
uniprot id: A0A3P8UVS1
names: Caution
names: Subcellular Location Annotation
messages: Endoplasmic reticulum
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Mitochondrion intermembrane space
messages: Mitochondrion outer membrane
messages: Rough endoplasmic reticulum
messages: cilium
messages: extracellular exosome
messages: extracellular space

244447:rrad
gene id: 244447:rrad
uniprot id: A0A3P8V4B1
names: Similarity
messages: Belongs to the small GTPase superfamily. RGK family.

244447:LOC103389137
gene id: 244447:LOC103389137
uniprot id: A0A3P8WLX4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GDNFR family.
messages: Cell membrane
messages: Membrane
messages: Receptor for neurturin. Mediates the NRTN-induced autophosphorylation and activation of the RET receptor. Also able to mediate GDNF signaling through the RET tyrosine kinase receptor.

244447:LOC103376636
gene id: 244447:LOC103376636
uniprot id: A0A3P8V6J5
names: Subcellular Location Annotation
messages: Nucleus

244447:LOC103384367
gene id: 244447:LOC103384367
uniprot id: A0A3P8WH15
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: PP1 comprises a catalytic subunit, and one or several targeting or regulatory subunits.

244447:LOC103383541
gene id: 244447:LOC103383541
uniprot id: A0A3P8WK48
names: Subcellular Location Annotation
messages: Early endosome
messages: Endosome

244447:usp1
gene id: 244447:usp1
uniprot id: A0A3P8WRZ0
names: Similarity
messages: Belongs to the peptidase C19 family.

244447:LOC103394988
gene id: 244447:LOC103394988
uniprot id: A0A3P8WTN2
names: Similarity
messages: Belongs to the ATP:guanido phosphotransferase family.

244447:csnk2a2
gene id: 244447:csnk2a2
uniprot id: A0A3P8W2E2
names: Similarity
messages: Belongs to the protein kinase superfamily.

244447:LOC103378806
gene id: 244447:LOC103378806
uniprot id: A0A3P8UQL2
names: Similarity
names: Subcellular Location Annotation
messages: Basolateral cell membrane
messages: Belongs to the potassium channel family. KQT (TC 1.A.1.15) subfamily. Kv7.1/KCNQ1 sub-subfamily.
messages: Cell membrane
messages: Cytoplasmic vesicle membrane
messages: Endoplasmic reticulum
messages: Lateral cell membrane
messages: Membrane
messages: Membrane raft

244447:vwa2
gene id: 244447:vwa2
uniprot id: A0A3P8V8K6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

244447:nat10
gene id: 244447:nat10
uniprot id: A0A3P8VZ79
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA cytidine acetyltransferase family. NAT10 subfamily.
messages: Interacts with THUMPD1.
messages: RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA-binding adapter protein THUMPD1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation.
messages: nucleolus

244447:aasdhppt
gene id: 244447:aasdhppt
uniprot id: A0A3P8WQB0
names: Similarity
messages: Belongs to the P-Pant transferase superfamily. AcpS family.

244447:LOC103398017
gene id: 244447:LOC103398017
uniprot id: A0A3P8VL03
names: Similarity
messages: Belongs to the complex I LYR family. SDHAF1 subfamily.

244447:LOC103389838
gene id: 244447:LOC103389838
uniprot id: A0A3P8VJ97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CD3Z/FCER1G family.
messages: Cell membrane
messages: Membrane

244447:LOC103397628
gene id: 244447:LOC103397628
uniprot id: A0A3P8WR18
names: Subcellular Location Annotation
messages: Membrane

244447:naa30
gene id: 244447:naa30
uniprot id: A0A3P8ULE1
names: Similarity
messages: Belongs to the acetyltransferase family. MAK3 subfamily.

244447:chdh
gene id: 244447:chdh
uniprot id: A0A3P8V6A0
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

244447:tmem121b
gene id: 244447:tmem121b
uniprot id: A0A3P8WFE1
names: Similarity
messages: Belongs to the TMEM121 family.

244447:gpr161
gene id: 244447:gpr161
uniprot id: A0A3P8USM2
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

244447:LOC103388355
gene id: 244447:LOC103388355
uniprot id: A0A3P8V1W4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family. GuaC type 1 subfamily.
messages: Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.
messages: Homotetramer.

244447:ndufaf7
gene id: 244447:ndufaf7
uniprot id: A0A3P8V0D3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Arginine methyltransferase involved in the assembly or stability of mitochondrial NADH:ubiquinone oxidoreductase complex (complex I).
messages: Belongs to the NDUFAF7 family.
messages: Mitochondrion

244447:LOC103394294
gene id: 244447:LOC103394294
uniprot id: A0A3P8WEU3
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

244447:LOC103379914
gene id: 244447:LOC103379914
uniprot id: A0A3P8UM35
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essential roles within the cell by associating with different regulatory particles. Associated with two 19S regulatory particles, forms the 26S proteasome and thus participates in the ATP-dependent degradation of ubiquitinated proteins. The 26S proteasome plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins that could impair cellular functions, and by removing proteins whose functions are no longer required. Associated with the PA200 or PA28, the 20S proteasome mediates ubiquitin-independent protein degradation. This type of proteolysis is required in several pathways including spermatogenesis (20S-PA200 complex) or generation of a subset of MHC class I-presented antigenic peptides (20S-PA28 complex).
messages: Cytoplasm
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.

244447:thumpd3
gene id: 244447:thumpd3
uniprot id: A0A3P8UUG7
names: Similarity
messages: Belongs to the methyltransferase superfamily.

244447:LOC103387241
gene id: 244447:LOC103387241
uniprot id: A0A3P8UWG5
names: Similarity
messages: Belongs to the PPase family.

244447:LOC103392698
gene id: 244447:LOC103392698
uniprot id: A0A3P8VEH1
names: Similarity
messages: Belongs to the UPF0585 family.

244447:ccdc85c
gene id: 244447:ccdc85c
uniprot id: A0A3P8WRS2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCDC85 family.
messages: adherens junction

244447:LOC103394526
gene id: 244447:LOC103394526
uniprot id: A0A3P8VE63
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CKS family.
messages: Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function.
messages: Forms a homohexamer that can probably bind six kinase subunits.

244447:gtf3c5
gene id: 244447:gtf3c5
uniprot id: A0A3P8UJC2
names: Subcellular Location Annotation
messages: Nucleus

244447:LOC103389244
gene id: 244447:LOC103389244
uniprot id: A0A3P8UGT6
names: Subcellular Location Annotation
messages: Nucleus

244447:pax8
gene id: 244447:pax8
uniprot id: A0A3P8WTV6
names: Subcellular Location Annotation
messages: Nucleus

244447:LOC103388053
gene id: 244447:LOC103388053
uniprot id: A0A3P8WYB0
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.

244447:mrps6
gene id: 244447:mrps6
uniprot id: A0A3P8VWG8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.

244447:LOC103395322
gene id: 244447:LOC103395322
uniprot id: A0A3P8W993
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

244447:LOC103388494
gene id: 244447:LOC103388494
uniprot id: A0A3P8VBM6
names: Cofactor
names: Similarity
messages: Belongs to the paraoxonase family.
messages: Binds 2 calcium ions per subunit.

244447:LOC103383017
gene id: 244447:LOC103383017
uniprot id: A0A3P8WKY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LRRC8 family.
messages: Cell membrane
messages: Membrane

244447:LOC103386507
gene id: 244447:LOC103386507
uniprot id: A0A3P8W613
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

244447:prps2
gene id: 244447:prps2
uniprot id: A0A3P8UYP6
names: Similarity
messages: Belongs to the ribose-phosphate pyrophosphokinase family.

244447:ing4
gene id: 244447:ing4
uniprot id: A0A3P8X369
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ING family.
messages: Component of an histone acetyltransferase complex.
messages: Component of an histone acetyltransferase complex. Interacts with H3K4me3 and to a lesser extent with H3K4me2.
messages: Nucleus
messages: The PHD-type zinc finger mediates the binding to H3K4me3.

244447:LOC103389306
gene id: 244447:LOC103389306
uniprot id: A0A3P8UP82
names: Similarity
messages: Belongs to the cholesterol 7-desaturase family.

244447:LOC103390352
gene id: 244447:LOC103390352
uniprot id: A0A3P8WYK9
uniprot id: A0A3P8WZ43
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UDP-glycosyltransferase family.
messages: Membrane

244447:st6galnac6
gene id: 244447:st6galnac6
uniprot id: A0A3P8W8L7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

244447:LOC103396062
gene id: 244447:LOC103396062
uniprot id: A0A3P8WH41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Bcl-2 family.
messages: Membrane

244447:cep44
gene id: 244447:cep44
uniprot id: A0A3P8VRD6
names: Subcellular Location Annotation
messages: Midbody
messages: centriole
messages: spindle pole

244447:LOC103395462
gene id: 244447:LOC103395462
uniprot id: A0A3P8WPW7
names: Similarity
messages: Belongs to the CD225/Dispanin family.

244447:gpat4
gene id: 244447:gpat4
uniprot id: A0A3P8VDQ5
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

244447:npc1
gene id: 244447:npc1
uniprot id: A0A3P8VUE3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the patched family.
messages: Membrane

244447:LOC103389933
gene id: 244447:LOC103389933
uniprot id: A0A3P8VV05
names: Similarity
messages: Belongs to the arrestin family.

244447:ints12
gene id: 244447:ints12
uniprot id: A0A3P8UQU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Integrator subunit 12 family.
messages: Nucleus

244447:pex13
gene id: 244447:pex13
uniprot id: A0A3P8UQI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxin-13 family.
messages: Membrane
messages: Peroxisome membrane

244447:hdac4
gene id: 244447:hdac4
uniprot id: A0A3P8UYV7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone deacetylase family. HD type 2 subfamily.
messages: Nucleus
messages: Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.

244447:LOC103382036
gene id: 244447:LOC103382036
uniprot id: A0A3P8WUY6
names: Subcellular Location Annotation
messages: extracellular space

244447:ubl3
gene id: 244447:ubl3
uniprot id: A0A3P8W2H2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

244447:LOC103384493
gene id: 244447:LOC103384493
uniprot id: A0A3P8WTD1
names: Subcellular Location Annotation
messages: sarcolemma

244447:LOC103393220
gene id: 244447:LOC103393220
uniprot id: A0A3P8WPY0
names: Similarity
messages: Belongs to the glycerophosphoryl diester phosphodiesterase family.

244447:LOC103392947
gene id: 244447:LOC103392947
uniprot id: A0A3P8W2S7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

244447:phb
gene id: 244447:phb
uniprot id: A0A3P8WFH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prohibitin family.
messages: Cell membrane
messages: Mitochondrion inner membrane

244447:lbr
gene id: 244447:lbr
uniprot id: A0A3P8WRB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERG4/ERG24 family.
messages: Cytoplasm
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Nucleus inner membrane

244447:pdcd10
gene id: 244447:pdcd10
uniprot id: A0A3P8UHF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PDCD10 family.
messages: Cell membrane
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Membrane

244447:LOC103381119
gene id: 244447:LOC103381119
uniprot id: A0A3P8UY08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.
messages: Nucleus

244447:crybb1
gene id: 244447:crybb1
uniprot id: A0A3P8VS94
names: Function
names: Similarity
names: Subunit
messages: Belongs to the beta/gamma-crystallin family.
messages: Crystallins are the dominant structural components of the vertebrate eye lens.
messages: Homo/heterodimer, or complexes of higher-order. The structure of beta-crystallin oligomers seems to be stabilized through interactions between the N-terminal arms.

244447:dlx3
gene id: 244447:dlx3
uniprot id: A0A3P8WT97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the distal-less homeobox family.
messages: Nucleus

244447:LOC103384195
gene id: 244447:LOC103384195
uniprot id: A0A3P8WB07
names: Similarity
messages: Belongs to the peptidase S1C family.

244447:LOC103382305
gene id: 244447:LOC103382305
uniprot id: A0A3P8UF58
names: Similarity
messages: Belongs to the JIP scaffold family.

244447:LOC103381636
gene id: 244447:LOC103381636
uniprot id: A0A3P8VRA0
names: Similarity
messages: Belongs to the peptidase C64 family.

244447:LOC103397926
gene id: 244447:LOC103397926
uniprot id: A0A3P8VH78
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.

244447:LOC103380935
gene id: 244447:LOC103380935
uniprot id: A0A3P8WZ49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ripply family.
messages: Nucleus

244447:kif7
gene id: 244447:kif7
uniprot id: A0A3P8V9Q4
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

244447:LOC103381707
gene id: 244447:LOC103381707
uniprot id: A0A3P8VZW3
names: Similarity
messages: Belongs to the UPF0488 family.

244447:mybl1
gene id: 244447:mybl1
uniprot id: A0A3P8WBR4
names: Subcellular Location Annotation
messages: Nucleus

244447:mettl15
gene id: 244447:mettl15
uniprot id: A0A3P8UF96
names: Similarity
messages: Belongs to the methyltransferase superfamily. RsmH family.

244447:scamp5
gene id: 244447:scamp5
uniprot id: A0A3P8VY53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCAMP family.
messages: Membrane

244447:lrp3
gene id: 244447:lrp3
uniprot id: A0A3P8VGK5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

244447:svop
gene id: 244447:svop
uniprot id: A0A3P8VCU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily.
messages: Membrane

244447:ogg1
gene id: 244447:ogg1
uniprot id: A0A3P8X105
names: Similarity
messages: Belongs to the type-1 OGG1 family.

244447:ctdp1
gene id: 244447:ctdp1
uniprot id: A0A3P8W3Q2
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: This promotes the activity of RNA polymerase II.

244447:LOC103383474
gene id: 244447:LOC103383474
uniprot id: A0A3P8WBE3
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

244447:LOC103384601
gene id: 244447:LOC103384601
uniprot id: A0A3P8UJL3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase.

244447:snrpf
gene id: 244447:snrpf
uniprot id: A0A3P8UYD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP Sm proteins family. SmF/LSm6 subfamily.
messages: Nucleus

244447:nxn
gene id: 244447:nxn
uniprot id: A0A3P8W9F5
names: Similarity
messages: Belongs to the nucleoredoxin family.

244447:LOC103387301
gene id: 244447:LOC103387301
uniprot id: A0A3P8V6W3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

244447:praf2
gene id: 244447:praf2
uniprot id: A0A3P8W5K1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA1 family.
messages: Membrane

244447:LOC107989142
gene id: 244447:LOC107989142
uniprot id: A0A3P8V252
names: Subcellular Location Annotation
messages: extracellular space

244447:stam2
gene id: 244447:stam2
uniprot id: A0A3P8UYQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STAM family.
messages: Early endosome membrane

244447:grid1
gene id: 244447:grid1
uniprot id: A0A3P8UTG8
uniprot id: A0A3P8UWK7
uniprot id: A0A3P8UWR6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

244447:map2k1
gene id: 244447:map2k1
uniprot id: A0A3P8VBW5
names: Similarity
messages: Belongs to the protein kinase superfamily.

244447:imp3
gene id: 244447:imp3
uniprot id: A0A3P8WN36
names: Similarity
messages: Belongs to the universal ribosomal protein uS4 family.

244447:LOC103378548
gene id: 244447:LOC103378548
uniprot id: A0A3P8WW27
names: Caution
names: Similarity
messages: Belongs to the secreted frizzled-related protein (sFRP) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

244447:LOC103377903
gene id: 244447:LOC103377903
uniprot id: A0A3P8V5D3
names: Function
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.
messages: May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway.

244447:cenpn
gene id: 244447:cenpn
uniprot id: A0A3P8WEM9
names: Similarity
messages: Belongs to the CENP-N/CHL4 family.

244447:parp2
gene id: 244447:parp2
uniprot id: A0A3P8X2L8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ARTD/PARP family.
messages: Nucleus

244447:LOC103385940
gene id: 244447:LOC103385940
uniprot id: A0A3P8UNJ1
names: Similarity
messages: Belongs to the VHL family.

244447:LOC103382520
gene id: 244447:LOC103382520
uniprot id: A0A3P8UWQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the potassium channel family. A (Shaker) (TC 1.A.1.2) subfamily. Kv1.5/KCNA5 sub-subfamily.
messages: Cell membrane
messages: Membrane

244447:tmem244
gene id: 244447:tmem244
uniprot id: A0A3P8WU83
names: Subcellular Location Annotation
messages: Membrane

244447:grk3
gene id: 244447:grk3
uniprot id: A0A3P8VXE4
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.

244447:LOC103393323
gene id: 244447:LOC103393323
uniprot id: A0A3P8V4X0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aconitase/IPM isomerase family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.
messages: Mitochondrion

244447:wdr83os
gene id: 244447:wdr83os
uniprot id: A0A3P8X552
names: Similarity
messages: Belongs to the Asterix family.

244447:ndufb3
gene id: 244447:ndufb3
uniprot id: A0A3P8VH76
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFB3 subunit family.
messages: Mitochondrion inner membrane

244447:LOC103395679
gene id: 244447:LOC103395679
uniprot id: A0A3P8V9G0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NIPA family.
messages: Membrane

244447:LOC103380370
gene id: 244447:LOC103380370
uniprot id: A0A3P8VCG2
uniprot id: A0A3P8VKM3
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

244447:LOC103392567
gene id: 244447:LOC103392567
uniprot id: A0A3P8X498
names: Subcellular Location Annotation
messages: Membrane

244447:LOC103377926
gene id: 244447:LOC103377926
uniprot id: A0A3P8V3A9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

244447:rad1
gene id: 244447:rad1
uniprot id: A0A3P8WWP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the rad1 family.
messages: Nucleus

244447:mcm7
gene id: 244447:mcm7
uniprot id: A0A3P8UW73
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.
messages: Belongs to the MCM family.
messages: Chromosome
messages: Nucleus

244447:b3gnt9
gene id: 244447:b3gnt9
uniprot id: A0A3P8X083
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

244447:nectin1
gene id: 244447:nectin1
uniprot id: A0A3P8VBM5
names: Subcellular Location Annotation
messages: Membrane

244447:scamp2
gene id: 244447:scamp2
uniprot id: A0A3P8ULW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCAMP family.
messages: Membrane

244447:LOC103380317
gene id: 244447:LOC103380317
uniprot id: A0A3P8VG28
uniprot id: A0A3P8VP31
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the fibulin family.
messages: Homomultimerizes and interacts with various extracellular matrix components.
messages: Incorporated into fibronectin-containing matrix fibers. May play a role in cell adhesion and migration along protein fibers within the extracellular matrix (ECM). Could be important for certain developmental processes and contribute to the supramolecular organization of ECM architecture, in particular to those of basement membranes.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

244447:lsm6
gene id: 244447:lsm6
uniprot id: A0A3P8UBH4
uniprot id: A0A3P8UFJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP Sm proteins family. SmF/LSm6 subfamily.
messages: Nucleus

244447:ybey
gene id: 244447:ybey
uniprot id: A0A3P8WGE7
names: Similarity
messages: Belongs to the endoribonuclease YbeY family.

244447:LOC103395096
gene id: 244447:LOC103395096
uniprot id: A0A3P8VMF9
names: Similarity
messages: Belongs to the band 7/mec-2 family.

244447:LOC103381756
gene id: 244447:LOC103381756
uniprot id: A0A3P8VXY9
names: Similarity
messages: Belongs to the MAGUK family.

244447:acp7
gene id: 244447:acp7
uniprot id: A0A3P8UCZ3
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. Purple acid phosphatase family.

244447:LOC103378156
gene id: 244447:LOC103378156
uniprot id: A0A3P8VQ32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Cationic amino acid transporter (CAT) (TC 2.A.3.3) family.
messages: Cell membrane
messages: Membrane

244447:pus3
gene id: 244447:pus3
uniprot id: A0A3P8VDM3
names: Similarity
messages: Belongs to the tRNA pseudouridine synthase TruA family.

244447:LOC103383189
gene id: 244447:LOC103383189
uniprot id: A0A3P8X0K2
names: Similarity
messages: Belongs to the cytochrome P450 family.

244447:LOC103385956
gene id: 244447:LOC103385956
uniprot id: A0A3P8UQC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family. Beta3-Gal-T subfamily.
messages: Membrane

244447:slc25a10
gene id: 244447:slc25a10
uniprot id: A0A3P8VAT0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

244447:LOC103380253
gene id: 244447:LOC103380253
uniprot id: A0A3P8V324
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.
messages: Cytoplasm
messages: Hydrolyzes ATP, and can also hydrolyze GTP with lower efficiency. Has lower affinity for GTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Nucleus
messages: nucleolus

244447:ccno
gene id: 244447:ccno
uniprot id: A0A3P8VEV1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cyclin family. Cyclin AB subfamily.
messages: Essential for the control of the cell cycle at the G2/M (mitosis) transition.
messages: Interacts with the CDK1 protein kinase to form a serine/threonine kinase holoenzyme complex also known as maturation promoting factor (MPF). The cyclin subunit imparts substrate specificity to the complex.

244447:dbnl
gene id: 244447:dbnl
uniprot id: A0A3P8VHD7
uniprot id: A0A3P8VHK8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABP1 family.
messages: Cell membrane
messages: Early endosome
messages: Endosome
messages: Golgi apparatus membrane
messages: Perikaryon
messages: Postsynaptic density
messages: Synapse
messages: cell cortex
messages: clathrin-coated vesicle membrane
messages: cytoskeleton
messages: dendrite
messages: lamellipodium
messages: neuron projection
messages: podosome
messages: ruffle

244447:LOC103394107
gene id: 244447:LOC103394107
uniprot id: A0A3P8W1A1
names: Subcellular Location Annotation
messages: Nucleus

244447:LOC103390624
gene id: 244447:LOC103390624
uniprot id: A0A3P8UPJ8
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

244447:eif1ax
gene id: 244447:eif1ax
uniprot id: A0A3P8W908
names: Function
names: Similarity
messages: Belongs to the eIF-1A family.
messages: Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits.

244447:LOC103390395
gene id: 244447:LOC103390395
uniprot id: A0A3P8UMF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GOLPH3/VPS74 family.
messages: Golgi stack membrane
messages: Membrane
messages: trans-Golgi network membrane

244447:slc37a3
gene id: 244447:slc37a3
uniprot id: A0A3P8VS37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family.
messages: Membrane

244447:LOC103396454
gene id: 244447:LOC103396454
uniprot id: A0A3P8WD22
names: Similarity
messages: Belongs to the SKI family.

244447:LOC103397057
gene id: 244447:LOC103397057
uniprot id: A0A3P8VV94
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

244447:get4
gene id: 244447:get4
uniprot id: A0A3P8WYI3
names: Similarity
messages: Belongs to the GET4 family.

244447:ppp4r3b
gene id: 244447:ppp4r3b
uniprot id: A0A3P8UKL7
names: Similarity
messages: Belongs to the SMEK family.

244447:lrig2
gene id: 244447:lrig2
uniprot id: A0A3P8WMB5
names: Subcellular Location Annotation
messages: Membrane

244447:LOC103377476
gene id: 244447:LOC103377476
uniprot id: A0A3P8UG19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Toll-like receptor family.
messages: Membrane

244447:psmb6
gene id: 244447:psmb6
uniprot id: A0A3P8V7H1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome complex.
messages: Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
messages: Cytoplasm
messages: Nucleus
messages: The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. This subunit is involved in antigen processing to generate class I binding peptides.

244447:LOC103389376
gene id: 244447:LOC103389376
uniprot id: A0A3P8UQ39
names: Similarity
messages: Belongs to the BZW family.

244447:kdm2a
gene id: 244447:kdm2a
uniprot id: A0A3P8VEP4
names: Similarity
messages: Belongs to the JHDM1 histone demethylase family. JHDM1D subfamily.

244447:LOC103389428
gene id: 244447:LOC103389428
uniprot id: A0A3P8V1B0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

244447:tor2a
gene id: 244447:tor2a
uniprot id: A0A3P8VP50
names: Similarity
messages: Belongs to the ClpA/ClpB family. Torsin subfamily.

244447:LOC103383813
gene id: 244447:LOC103383813
uniprot id: A0A3P8VIA6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

244447:chaf1a
gene id: 244447:chaf1a
uniprot id: A0A3P8VAC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CHAF1A family.
messages: Nucleus

244447:LOC103381862
gene id: 244447:LOC103381862
uniprot id: A0A3P8W786
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Required for vesicle-mediated transport. Catalyzes the fusion of transport vesicles within the Golgi cisternae. Is also required for transport from the endoplasmic reticulum to the Golgi stack. Seems to function as a fusion protein required for the delivery of cargo proteins to all compartments of the Golgi stack independent of vesicle origin.

244447:LOC103387265
gene id: 244447:LOC103387265
uniprot id: A0A3P8V679
names: Similarity
messages: Belongs to the Ntn-hydrolase family.

244447:LOC103385082
gene id: 244447:LOC103385082
uniprot id: A0A3P8WNH3
names: Subcellular Location Annotation
messages: Nucleus

244447:LOC103393644
gene id: 244447:LOC103393644
uniprot id: A0A3P8WE14
uniprot id: A0A3P8WGW5
names: Subcellular Location Annotation
messages: Endosome membrane
messages: Membrane

244447:LOC103388604
gene id: 244447:LOC103388604
uniprot id: A0A3P8VPB3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ELO family. ELOVL4 subfamily.
messages: Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that specifically elongates C24:0 and C26:0 acyl-CoAs. May participate to the production of saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Oligomer.

244447:tspan8
gene id: 244447:tspan8
uniprot id: A0A3P8UTQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

244447:sdhd
gene id: 244447:sdhd
uniprot id: A0A3P8V0M4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CybS family.
messages: Component of complex II composed of four subunits: the flavoprotein (FP) SDHA, iron-sulfur protein (IP) SDHB, and a cytochrome b560 composed of SDHC and SDHD.
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).
messages: Mitochondrion inner membrane

244447:sgk2
gene id: 244447:sgk2
uniprot id: A0A3P8WVV4
names: Similarity
messages: Belongs to the protein kinase superfamily.

244447:sirt3
gene id: 244447:sirt3
uniprot id: A0A3P8V9W0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the sirtuin family. Class I subfamily.
messages: Binds 1 zinc ion per subunit.
messages: NAD-dependent protein deacetylase.

244447:LOC103380320
gene id: 244447:LOC103380320
uniprot id: A0A3P8VG59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Nucleus

244447:lmf1
gene id: 244447:lmf1
uniprot id: A0A3P8X1M1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lipase maturation factor family.
messages: Endoplasmic reticulum membrane
messages: Involved in the maturation of specific proteins in the endoplasmic reticulum.
messages: Membrane

244447:LOC103393959
gene id: 244447:LOC103393959
uniprot id: A0A3P8VL93
names: Similarity
messages: Belongs to the intermediate filament family.

244447:taf5l
gene id: 244447:taf5l
uniprot id: A0A3P8VW69
names: Similarity
messages: Belongs to the WD repeat TAF5 family.

244447:LOC103396459
gene id: 244447:LOC103396459
uniprot id: A0A3P8W8A6
names: Subcellular Location Annotation
messages: Cytoplasm

244447:slc39a14
gene id: 244447:slc39a14
uniprot id: A0A3P8X3D5
names: Subcellular Location Annotation
messages: Membrane

244447:cnot8
gene id: 244447:cnot8
uniprot id: A0A3P8X2P9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAF1 family.
messages: Nucleus

244447:vegfb
gene id: 244447:vegfb
uniprot id: A0A3P8V6V8
names: Similarity
messages: Belongs to the PDGF/VEGF growth factor family.

244447:LOC103383191
gene id: 244447:LOC103383191
uniprot id: A0A3P8UHE0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: gap junction

244447:mff
gene id: 244447:mff
uniprot id: A0A3P8UP95
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tango11 family.
messages: Membrane
messages: Mitochondrion outer membrane
messages: Peroxisome
messages: Plays a role in mitochondrial and peroxisomal fission. Promotes the recruitment and association of the fission mediator dynamin-related protein 1 (DNM1L) to the mitochondrial surface.

244447:wif1
gene id: 244447:wif1
uniprot id: A0A3P8W9X8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

244447:sfxn1
gene id: 244447:sfxn1
uniprot id: A0A3P8WHL4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sideroflexin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Mitochondrion membrane

244447:LOC103384248
gene id: 244447:LOC103384248
uniprot id: A0A3P8WBI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

244447:plpp3
gene id: 244447:plpp3
uniprot id: A0A3P8V2M6
uniprot id: A0A3P8V2N2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Membrane

244447:gtf2a1
gene id: 244447:gtf2a1
uniprot id: A0A3P8WSU1
uniprot id: A0A3P8WXZ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFIIA subunit 1 family.
messages: Nucleus

244447:ppp5c
gene id: 244447:ppp5c
uniprot id: A0A3P8V676
names: Similarity
messages: Belongs to the PPP phosphatase family. PP-5 (PP-T) subfamily.

244447:LOC103388716
gene id: 244447:LOC103388716
uniprot id: A0A3P8VNP4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Cell membrane
messages: Membrane
messages: Membrane raft
messages: Transmembrane serine/threonine kinase forming with the TGF-beta type I serine/threonine kinase receptor, TGFBR1, the non-promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinogenesis. The formation of the receptor complex composed of 2 TGFBR1 and 2 TGFBR2 molecules symmetrically bound to the cytokine dimer results in the phosphorylation and the activation of TGFRB1 by the constitutively active TGFBR2. Activated TGFBR1 phosphorylates SMAD2 which dissociates from the receptor and interacts with SMAD4. The SMAD2-SMAD4 complex is subsequently translocated to the nucleus where it modulates the transcription of the TGF-beta-regulated genes. This constitutes the canonical SMAD-dependent TGF-beta signaling cascade. Also involved in non-canonical, SMAD-independent TGF-beta signaling pathways.

244447:LOC103396642
gene id: 244447:LOC103396642
uniprot id: A0A3P8X259
names: Similarity
messages: Belongs to the SAPAP family.

244447:amd1
gene id: 244447:amd1
uniprot id: A0A3P8WB20
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the eukaryotic AdoMetDC family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Essential for biosynthesis of the polyamines spermidine and spermine. Promotes maintenance and self-renewal of embryonic stem cells, by maintaining spermine levels.

244447:LOC103389196
gene id: 244447:LOC103389196
uniprot id: A0A3P8WWK0
names: Similarity
messages: Belongs to the glutamine synthetase family.

244447:LOC103379180
gene id: 244447:LOC103379180
uniprot id: A0A3P8VA73
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the p22phox family.
messages: Cell membrane
messages: Composed of a heavy chain (beta) and a light chain (alpha). Component of an NADPH oxidase complex composed of a heterodimer formed by the membrane proteins CYBA and CYBB and the cytosolic subunits NCF1, NCF2 and NCF4. Interacts with NCF1 (via SH3 domain).
messages: Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. Associates with NOX3 to form a functional NADPH oxidase constitutively generating superoxide.
messages: Membrane

244447:LOC103388750
gene id: 244447:LOC103388750
uniprot id: A0A3P8VQJ6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycosyl hydrolase 27 family.
messages: Homodimer.
messages: Lysosome

244447:ube2b
gene id: 244447:ube2b
uniprot id: A0A3P8W8K1
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

244447:cth
gene id: 244447:cth
uniprot id: A0A3P8VDD7
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

244447:LOC103395072
gene id: 244447:LOC103395072
uniprot id: A0A3P8WU16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POU transcription factor family. Class-2 subfamily.
messages: Nucleus

244447:sidt2
gene id: 244447:sidt2
uniprot id: A0A3P8UPI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SID1 family.
messages: Membrane

244447:LOC103376743
gene id: 244447:LOC103376743
uniprot id: A0A3P8VBI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the hcp beta-lactamase family.
messages: Mitochondrion intermembrane space

244447:LOC103377374
gene id: 244447:LOC103377374
uniprot id: A0A3P8X036
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mediator complex subunit 1 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Nucleus

244447:LOC103392726
gene id: 244447:LOC103392726
uniprot id: A0A3P8VND9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

244447:slc46a2
gene id: 244447:slc46a2
uniprot id: A0A3P8WYK2
names: Subcellular Location Annotation
messages: Membrane

244447:LOC103390129
gene id: 244447:LOC103390129
uniprot id: A0A3P8WDP4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UQCR10/QCR9 family.
messages: Component of the ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII), a multisubunit enzyme composed of 3 respiratory subunits cytochrome b, cytochrome c1 and Rieske protein, 2 core protein subunits, and additional low-molecular weight protein subunits.
messages: Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. The cytochrome b-c1 complex catalyzes electron transfer from ubiquinol to cytochrome c, linking this redox reaction to translocation of protons across the mitochondrial inner membrane, with protons being carried across the membrane as hydrogens on the quinol. In the process called Q cycle, 2 protons are consumed from the matrix, 4 protons are released into the intermembrane space and 2 electrons are passed to cytochrome c.
messages: Membrane
messages: Mitochondrion inner membrane

244447:LOC103383199
gene id: 244447:LOC103383199
uniprot id: A0A3P8X0B6
names: Similarity
messages: Belongs to the GDA1/CD39 NTPase family.

244447:ppp2cb
gene id: 244447:ppp2cb
uniprot id: A0A3P8VLY3
names: Similarity
messages: Belongs to the PPP phosphatase family.

244447:slc39a1
gene id: 244447:slc39a1
uniprot id: A0A3P8W7S2
names: Subcellular Location Annotation
messages: Membrane

244447:fermt1
gene id: 244447:fermt1
uniprot id: A0A3P8UT00
names: Similarity
messages: Belongs to the kindlin family.

244447:LOC103381010
gene id: 244447:LOC103381010
uniprot id: A0A3P8UIP2
names: Similarity
messages: Belongs to the YY transcription factor family.

244447:LOC103397627
gene id: 244447:LOC103397627
uniprot id: A0A3P8WWX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCAMP family.
messages: Membrane

244447:cuta
gene id: 244447:cuta
uniprot id: A0A3P8UN48
names: Similarity
names: Subunit
messages: Belongs to the CutA family.
messages: Homotrimer.

244447:samd4b
gene id: 244447:samd4b
uniprot id: A0A3P8VSA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMAUG family.
messages: Cytoplasm

244447:hsf4
gene id: 244447:hsf4
uniprot id: A0A3P8X0B7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSF family.
messages: Nucleus

244447:gpr157
gene id: 244447:gpr157
uniprot id: A0A3P8VD19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 5 family.
messages: Membrane

244447:mtif3
gene id: 244447:mtif3
uniprot id: A0A3P8UY43
names: Similarity
messages: Belongs to the IF-3 family.

244447:LOC103378848
gene id: 244447:LOC103378848
uniprot id: A0A3P8V0W2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

244447:LOC103383730
gene id: 244447:LOC103383730
uniprot id: A0A3P8V5F0
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.

244447:bok
gene id: 244447:bok
uniprot id: A0A3P8VGS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Bcl-2 family.
messages: Membrane

244447:lig3
gene id: 244447:lig3
uniprot id: A0A3P8W685
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP-dependent DNA ligase family.
messages: Nucleus

244447:ypel1
gene id: 244447:ypel1
uniprot id: A0A3P8VHK3
names: Similarity
messages: Belongs to the yippee family.

244447:adamts20
gene id: 244447:adamts20
uniprot id: A0A3P8V9A2
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

244447:opn3
gene id: 244447:opn3
uniprot id: A0A3P8VIT9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
messages: Membrane

244447:lztfl1
gene id: 244447:lztfl1
uniprot id: A0A3P8WSW9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LZTFL1 family.
messages: Cytoplasm
messages: Regulates ciliary localization of the BBSome complex. Together with the BBSome complex, controls SMO ciliary trafficking and contributes to the sonic hedgehog (SHH) pathway regulation. May play a role in neurite outgrowth. May have tumor suppressor function.
messages: Self-associates. Interacts with BBS9; the interaction mediates the association of LZTL1 with the BBsome complex and regulates BBSome ciliary trafficking.

244447:ca12
gene id: 244447:ca12
uniprot id: A0A3P8UMH6
names: Function
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

244447:coq8a
gene id: 244447:coq8a
uniprot id: A0A3P8WT90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. ADCK protein kinase family.
messages: Membrane
messages: Mitochondrion

244447:evpl
gene id: 244447:evpl
uniprot id: A0A3P8VHC7
names: Subcellular Location Annotation
messages: cytoskeleton

244447:nit2
gene id: 244447:nit2
uniprot id: A0A3P8VEZ4
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

244447:LOC103395386
gene id: 244447:LOC103395386
uniprot id: A0A3P8WHE7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Membrane
messages: The small GTPases Rab are key regulators in vesicle trafficking.

244447:LOC103381810
gene id: 244447:LOC103381810
uniprot id: A0A3P8W688
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

244447:tgfb2
gene id: 244447:tgfb2
uniprot id: A0A3P8VQE7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TGF-beta family.
messages: Homodimer; disulfide-linked.
messages: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-2 (TGF-beta-2) chains, which constitute the regulatory and active subunit of TGF-beta-2, respectively.
messages: extracellular matrix

244447:chmp4b
gene id: 244447:chmp4b
uniprot id: A0A3P8WVQ0
names: Similarity
messages: Belongs to the SNF7 family.

244447:LOC103397504
gene id: 244447:LOC103397504
uniprot id: A0A3P8W975
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM161 family.
messages: Membrane

244447:alkbh8
gene id: 244447:alkbh8
uniprot id: A0A3P8WN81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alkB family.
messages: Cytoplasm

244447:fzd2
gene id: 244447:fzd2
uniprot id: A0A3P8WQZ6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor Fz/Smo family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

244447:LOC103389706
gene id: 244447:LOC103389706
uniprot id: A0A3P8VWW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FUN14 family.
messages: Mitochondrion outer membrane

244447:slc2a4
gene id: 244447:slc2a4
uniprot id: A0A3P8UUQ8
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

244447:LOC103387304
gene id: 244447:LOC103387304
uniprot id: A0A3P8V3P6
names: Subcellular Location Annotation
messages: Nucleus

244447:LOC103385228
gene id: 244447:LOC103385228
uniprot id: A0A3P8W8V3
uniprot id: A0A3P8WEP5
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

244447:LOC103397460
gene id: 244447:LOC103397460
uniprot id: A0A3P8VQ63
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Catalyzes the conversion of phosphatidic acid (PA) to CDP-diacylglycerol (CDP-DAG), an essential intermediate in the synthesis of phosphatidylglycerol, cardiolipin and phosphatidylinositol.
messages: Membrane

244447:si
gene id: 244447:si
uniprot id: A0A3P8UJN3
names: Caution
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

244447:sgcg
gene id: 244447:sgcg
uniprot id: A0A3P8UNX4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sarcoglycan beta/delta/gamma/zeta family.
messages: Component of the sarcoglycan complex, a subcomplex of the dystrophin-glycoprotein complex which forms a link between the F-actin cytoskeleton and the extracellular matrix.
messages: cytoskeleton
messages: sarcolemma

244447:trappc13
gene id: 244447:trappc13
uniprot id: A0A3P8W4P5
uniprot id: A0A3P8WAJ6
names: Similarity
names: Subunit
messages: Belongs to the TRAPPC13 family.
messages: Part of the multisubunit TRAPP (transport protein particle) complex.

244447:LOC103398136
gene id: 244447:LOC103398136
uniprot id: A0A3P8W2T9
names: Similarity
messages: Belongs to the arrestin family.

244447:smad9
gene id: 244447:smad9
uniprot id: A0A3P8VXP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dwarfin/SMAD family.
messages: Cytoplasm
messages: Nucleus

244447:ankle2
gene id: 244447:ankle2
uniprot id: A0A3P8VU69
names: Similarity
messages: Belongs to the ANKLE2 family.

244447:trim9
gene id: 244447:trim9
uniprot id: A0A3P8V8T5
uniprot id: A0A3P8VEU5
uniprot id: A0A3P8VH01
names: Subcellular Location Annotation
messages: cytoskeleton

244447:LOC103390226
gene id: 244447:LOC103390226
uniprot id: A0A3P8WTG4
uniprot id: A0A3P8WVU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TNF receptor-associated factor family.
messages: Cytoplasm

244447:arpc1b
gene id: 244447:arpc1b
uniprot id: A0A3P8UM20
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat ARPC1 family.
messages: Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.
messages: Nucleus
messages: cytoskeleton

244447:LOC103396430
gene id: 244447:LOC103396430
uniprot id: A0A3P8W573
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

244447:mlst8
gene id: 244447:mlst8
uniprot id: A0A3P8UHP2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat LST8 family.
messages: Cytoplasm
messages: Part of TORC1 complex. Part of the TORC2 complex.
messages: Subunit of TORC1 and TORC2, which regulate cell growth and survival in response to nutrient and hormonal signals.

244447:hip1r
gene id: 244447:hip1r
uniprot id: A0A3P8W5Y9
names: Similarity
messages: Belongs to the SLA2 family.

244447:LOC103386026
gene id: 244447:LOC103386026
uniprot id: A0A0K2FPZ2
names: Similarity
messages: Belongs to the NRAMP family.

244447:LOC103386756
gene id: 244447:LOC103386756
uniprot id: A0A3P8WUM5
names: Subcellular Location Annotation
names: Subunit
messages: Efficient DNA binding requires dimerization with another bHLH protein. Binds DNA as a heterodimer with MAX.
messages: Nucleus

244447:mon2
gene id: 244447:mon2
uniprot id: A0A3P8VN72
names: Similarity
messages: Belongs to the MON2 family.

244447:ddc
gene id: 244447:ddc
uniprot id: A0A3P8VSD1
names: Similarity
names: Subunit
messages: Belongs to the group II decarboxylase family.
messages: Homodimer.

244447:LOC103385447
gene id: 244447:LOC103385447
uniprot id: A0A3P8X3B4
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane
messages: Membrane

244447:LOC103397767
gene id: 244447:LOC103397767
uniprot id: A0A3P8WZR2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-X family.
messages: Cytoplasm
messages: DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template-independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity.
messages: Nucleus
messages: Repair polymerase that plays a key role in base-excision repair. Has 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity that removes the 5' sugar phosphate and also acts as a DNA polymerase that adds one nucleotide to the 3' end of the arising single-nucleotide gap. Conducts 'gap-filling' DNA synthesis in a stepwise distributive fashion rather than in a processive fashion as for other DNA polymerases.

244447:LOC103388493
gene id: 244447:LOC103388493
uniprot id: A0A3P8VH82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

244447:exoc6
gene id: 244447:exoc6
uniprot id: A0A3P8VZ67
names: Function
names: Similarity
messages: Belongs to the SEC15 family.
messages: Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.

244447:arrb2
gene id: 244447:arrb2
uniprot id: A0A3P8X3P3
names: Similarity
messages: Belongs to the arrestin family.

244447:LOC103378177
gene id: 244447:LOC103378177
uniprot id: A0A3P8VSG6
uniprot id: A0A3P8VXW7
names: Subcellular Location Annotation
messages: Cytoplasm

244447:LOC103395242
gene id: 244447:LOC103395242
uniprot id: A0A3P8W054
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.
messages: Belongs to the replication factor A protein 1 family.
messages: Component of the heterotrimeric canonical replication protein A complex (RPA).
messages: PML body

244447:robo3
gene id: 244447:robo3
uniprot id: A0A3P8WRD8
names: Subcellular Location Annotation
messages: Membrane

244447:LOC103395356
gene id: 244447:LOC103395356
uniprot id: A0A3P8W8M7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Aquaporins facilitate the transport of water and small neutral solutes across cell membranes.
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

244447:mfap2
gene id: 244447:mfap2
uniprot id: A0A3P8UQT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MFAP family.
messages: extracellular matrix

244447:dohh
gene id: 244447:dohh
uniprot id: A0A3P8WVC8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the deoxyhypusine hydroxylase family.
messages: Binds 2 Fe(2+) ions per subunit.
messages: Catalyzes the hydroxylation of the N(6)-(4-aminobutyl)-L-lysine intermediate to form hypusine, an essential post-translational modification only found in mature eIF-5A factor.

244447:psme2
gene id: 244447:psme2
uniprot id: A0A3P8W8W7
names: Similarity
messages: Belongs to the PA28 family.

244447:chst10
gene id: 244447:chst10
uniprot id: A0A3P8VRB2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 2 family.
messages: Golgi apparatus membrane
messages: Membrane

244447:eif3j
gene id: 244447:eif3j
uniprot id: A0A3P8UNA2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit J family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
messages: Cytoplasm

244447:mrps21
gene id: 244447:mrps21
uniprot id: A0A3P8VDD4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

244447:gadd45a
gene id: 244447:gadd45a
uniprot id: A0A3P8WMJ2
names: Similarity
messages: Belongs to the GADD45 family.

244447:scap
gene id: 244447:scap
uniprot id: A0A3P8W8C1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat SCAP family.
messages: COPII-coated vesicle membrane
messages: Golgi apparatus membrane

244447:gchfr
gene id: 244447:gchfr
uniprot id: A0A3P8UCN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GFRP family.
messages: Membrane
messages: Nucleus membrane
messages: cytosol

244447:LOC103385331
gene id: 244447:LOC103385331
uniprot id: A0A3P8WVB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urotensin-2 family.
messages: Secreted

244447:pdk3
gene id: 244447:pdk3
uniprot id: A0A3P8VUN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PDK/BCKDK protein kinase family.
messages: Mitochondrion matrix

244447:LOC103391057
gene id: 244447:LOC103391057
uniprot id: A0A3P8W3W4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat SMU1 family.
messages: Nucleus speckle

244447:pms2
gene id: 244447:pms2
uniprot id: A0A3P8UL58
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.

244447:pdf
gene id: 244447:pdf
uniprot id: A0A3P8UDA8
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins.

244447:LOC103389904
gene id: 244447:LOC103389904
uniprot id: A0A3P8VZ35
names: Subcellular Location Annotation
messages: Golgi apparatus membrane
messages: Membrane

244447:LOC103383236
gene id: 244447:LOC103383236
uniprot id: A0A3P8X0V3
names: Similarity
messages: Belongs to the PDGF/VEGF growth factor family.

244447:LOC103376919
gene id: 244447:LOC103376919
uniprot id: A0A3P8VGT6
names: Similarity
messages: Belongs to the carotenoid oxygenase family.

244447:LOC103386095
gene id: 244447:LOC103386095
uniprot id: A0A3P8UZM3
names: Similarity
messages: Belongs to the TGF-beta family.

244447:LOC103397234
gene id: 244447:LOC103397234
uniprot id: A0A3P8WBF8
names: Similarity
messages: Belongs to the TGF-beta family.

244447:LOC103384941
gene id: 244447:LOC103384941
uniprot id: A0A3P8V272
names: Subcellular Location Annotation
messages: extracellular space

244447:LOC103386123
gene id: 244447:LOC103386123
uniprot id: A0A3P8V2T5
names: Similarity
messages: Belongs to the lipin family.

244447:scfd2
gene id: 244447:scfd2
uniprot id: A0A3P8WXQ7
names: Similarity
messages: Belongs to the STXBP/unc-18/SEC1 family.

244447:gpx8
gene id: 244447:gpx8
uniprot id: A0A3P8VET7
names: Similarity
messages: Belongs to the glutathione peroxidase family.

244447:klc1
gene id: 244447:klc1
uniprot id: A0A3P8W7R3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the kinesin light chain family.
messages: Kinesin is a microtubule-associated force-producing protein that play a role in organelle transport.
messages: Oligomeric complex composed of two heavy chains and two light chains.
messages: cytoskeleton

244447:LOC103396965
gene id: 244447:LOC103396965
uniprot id: A0A3P8VFR9
uniprot id: A0A3P8VP16
names: Similarity
messages: Belongs to the ataxin-2 family.

244447:LOC103395387
gene id: 244447:LOC103395387
uniprot id: A0A3P8WMZ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 3 family.
messages: Cell membrane
messages: Membrane

244447:LOC103385324
gene id: 244447:LOC103385324
uniprot id: A0A3P8WQ06
names: Similarity
messages: Belongs to the PPP4R2 family.

244447:LOC103386277
gene id: 244447:LOC103386277
uniprot id: A0A3P8VEE1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 3 family.
messages: Cell membrane
messages: Membrane

244447:aar2
gene id: 244447:aar2
uniprot id: A0A3P8WZ55
names: Function
names: Similarity
messages: Belongs to the AAR2 family.
messages: Component of the U5 snRNP complex that is required for spliceosome assembly and for pre-mRNA splicing.

244447:LOC103381313
gene id: 244447:LOC103381313
uniprot id: A0A3P8UZH8
names: Similarity
messages: Belongs to the cytochrome c oxidase VIIa family.

244447:glyctk
gene id: 244447:glyctk
uniprot id: A0A3P8X764
names: Similarity
messages: Belongs to the glycerate kinase type-2 family.

244447:LOC103397980
gene id: 244447:LOC103397980
uniprot id: A0A3P8VL92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM163 family.
messages: Membrane

244447:LOC103396490
gene id: 244447:LOC103396490
uniprot id: A0A3P8WFK7
names: Subcellular Location Annotation
messages: Secreted
messages: Synapse

244447:sms
gene id: 244447:sms
uniprot id: A0A3P8VI37
names: Similarity
messages: Belongs to the spermidine/spermine synthase family.

244447:adprm
gene id: 244447:adprm
uniprot id: A0A3P8UVK3
names: Similarity
names: Subunit
messages: Belongs to the ADPRibase-Mn family.
messages: Monomer.

244447:LOC103381893
gene id: 244447:LOC103381893
uniprot id: A0A3P8WAR5
names: Similarity
messages: Belongs to the syntaxin family.

244447:naa25
gene id: 244447:naa25
uniprot id: A0A3P8W167
names: Similarity
messages: Belongs to the MDM20/NAA25 family.

244447:acaa2
gene id: 244447:acaa2
uniprot id: A0A3P8WVP5
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

244447:sf3b6
gene id: 244447:sf3b6
uniprot id: A0A3P8WY82
names: Subcellular Location Annotation
messages: Nucleus

244447:LOC103393031
gene id: 244447:LOC103393031
uniprot id: A0A3P8W9H6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERD2 family.
messages: COPI-coated vesicle membrane
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

244447:wtap
gene id: 244447:wtap
uniprot id: A0A3P8UJX2
names: Similarity
messages: Belongs to the fl(2)d family.

244447:LOC103386050
gene id: 244447:LOC103386050
uniprot id: A0A3P8V0Q7
names: Subcellular Location Annotation
messages: Membrane

244447:LOC103381921
gene id: 244447:LOC103381921
uniprot id: A0A3P8WIC5
names: Subcellular Location Annotation
names: Subunit
messages: May interact with TSPO.
messages: Mitochondrion

244447:LOC103398295
gene id: 244447:LOC103398295
uniprot id: A0A3P8WGG3
uniprot id: A0A3P8WM28
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family. PDE4 subfamily.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

244447:wrnip1
gene id: 244447:wrnip1
uniprot id: A0A3P8VLI2
uniprot id: A0A3P8VPK3
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

244447:LOC103381975
gene id: 244447:LOC103381975
uniprot id: A0A3P8WQR5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit C family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
messages: Cytoplasm

244447:LOC103397605
gene id: 244447:LOC103397605
uniprot id: A0A3P8WQA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UDP-glycosyltransferase family.
messages: Membrane

244447:slc25a46
gene id: 244447:slc25a46
uniprot id: A0A3P8WYR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion outer membrane

244447:man2a1
gene id: 244447:man2a1
uniprot id: A0A3P8WWZ7
names: Cofactor
names: Similarity
messages: Belongs to the glycosyl hydrolase 38 family.
messages: Binds 1 zinc ion per subunit.

244447:slc19a1
gene id: 244447:slc19a1
uniprot id: A0A3P8UNL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the reduced folate carrier (RFC) transporter (TC 2.A.48) family.
messages: Membrane

244447:LOC103377624
gene id: 244447:LOC103377624
uniprot id: A0A3P8UJM2
names: Subcellular Location Annotation
messages: Nucleus

244447:LOC103387892
gene id: 244447:LOC103387892
uniprot id: A0A3P8UZ59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase VIII family.
messages: Membrane
messages: Mitochondrion inner membrane

244447:brinp1
gene id: 244447:brinp1
uniprot id: A0A3P8WQN7
names: Similarity
messages: Belongs to the BRINP family.

244447:slc14a1
gene id: 244447:slc14a1
uniprot id: A0A3P8WIH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urea transporter family.
messages: Cell membrane
messages: Membrane

244447:LOC103383557
gene id: 244447:LOC103383557
uniprot id: A0A3P8UWJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ubiquitin family. SUMO subfamily.
messages: Nucleus

244447:slc20a1
gene id: 244447:slc20a1
uniprot id: A0A3P8WN65
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane
messages: Sodium-phosphate symporter which plays a fundamental housekeeping role in phosphate transport.

244447:LOC103390655
gene id: 244447:LOC103390655
uniprot id: A0A3P8UZ73
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Endosome
messages: Membrane
messages: This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that stimulate adenylate cyclase.

244447:LOC103397732
gene id: 244447:LOC103397732
uniprot id: A0A3P8WXY2
names: Function
names: Similarity
messages: Belongs to the KCMF1 family.
messages: Has intrinsic E3 ubiquitin ligase activity and promotes ubiquitination.

244447:LOC103389235
gene id: 244447:LOC103389235
uniprot id: A0A3P8UG87
uniprot id: A0A3P8UME9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Receptor class 8 subfamily.
messages: Membrane
messages: secretory vesicle membrane

244447:LOC103378148
gene id: 244447:LOC103378148
uniprot id: A0A3P8VSM6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

244447:wnt16
gene id: 244447:wnt16
uniprot id: A0A3P8UY39
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

244447:LOC103397876
gene id: 244447:LOC103397876
uniprot id: A0A3P8WXC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ACDP family.
messages: Membrane

244447:hsdl2
gene id: 244447:hsdl2
uniprot id: A0A3P8WZE5
names: Subcellular Location Annotation
messages: Peroxisome

244447:spo11
gene id: 244447:spo11
uniprot id: A0A3P8WZD1
names: Similarity
messages: Belongs to the TOP6A family.

244447:copg2
gene id: 244447:copg2
uniprot id: A0A3P8VAN0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the COPG family.
messages: COPI-coated vesicle membrane
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Membrane
messages: Oligomeric complex.
messages: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.

244447:exoc5
gene id: 244447:exoc5
uniprot id: A0A3P8UDC0
names: Function
names: Similarity
messages: Belongs to the SEC10 family.
messages: Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.

244447:foxa2
gene id: 244447:foxa2
uniprot id: A0A3P8UDY1
names: Subcellular Location Annotation
messages: Nucleus

244447:srpx2
gene id: 244447:srpx2
uniprot id: A0A3P8UQF0
names: Caution
names: Subcellular Location Annotation
messages: Cell surface
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted
messages: Synapse

244447:ada2
gene id: 244447:ada2
uniprot id: A0A3P8V8F7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. ADGF subfamily.
messages: Secreted

244447:LOC103388849
gene id: 244447:LOC103388849
uniprot id: A0A3P8VY71
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 7 family.
messages: Golgi apparatus membrane
messages: Membrane
messages: Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids.

244447:LOC103390401
gene id: 244447:LOC103390401
uniprot id: A0A3P8UDN9
names: Similarity
messages: Belongs to the TGF-beta family.

244447:ccser1
gene id: 244447:ccser1
uniprot id: A0A3P8V3Z4
uniprot id: A0A3P8V7Q2
names: Similarity
messages: Belongs to the CCSER family.

244447:LOC103399914
gene id: 244447:LOC103399914
uniprot id: A0A3P8UV89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the potassium channel HCN family.
messages: Cell membrane
messages: Membrane

244447:LOC103392544
gene id: 244447:LOC103392544
uniprot id: A0A3P8WXM4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cyclin family. Cyclin AB subfamily.
messages: Essential for the control of the cell cycle at the G2/M (mitosis) transition.
messages: Interacts with the CDK1 protein kinase to form a serine/threonine kinase holoenzyme complex also known as maturation promoting factor (MPF). The cyclin subunit imparts substrate specificity to the complex.

244447:cstf3
gene id: 244447:cstf3
uniprot id: A0A3P8W9W9
names: Subcellular Location Annotation
messages: Nucleus

244447:nab1
gene id: 244447:nab1
uniprot id: A0A3P8V5S3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NAB family.
messages: Homomultimers may associate with EGR1 bound to DNA.
messages: Nucleus

244447:LOC103381409
gene id: 244447:LOC103381409
uniprot id: A0A3P8V552
names: Similarity
messages: Belongs to the SMARCD family.

244447:hspa9
gene id: 244447:hspa9
uniprot id: A0A3P8URL0
names: Similarity
messages: Belongs to the heat shock protein 70 family.

244447:LOC103391080
gene id: 244447:LOC103391080
uniprot id: A0A3P8VX43
names: Subcellular Location Annotation
messages: Membrane

244447:txn
gene id: 244447:txn
uniprot id: I3VA01
names: Similarity
messages: Belongs to the thioredoxin family.

244447:LOC103382313
gene id: 244447:LOC103382313
uniprot id: E2JF88
names: Similarity
messages: Belongs to the globin family.

244447:fuz
gene id: 244447:fuz
uniprot id: A0A3P8VWK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fuzzy family.
messages: cytoskeleton

244447:LOC103389672
gene id: 244447:LOC103389672
uniprot id: A0A3P8VPY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

244447:LOC103392434
gene id: 244447:LOC103392434
uniprot id: A0A3P8WRZ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

244447:tmem161a
gene id: 244447:tmem161a
uniprot id: A0A3P8V7E3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM161 family.
messages: Membrane

244447:dirc2
gene id: 244447:dirc2
uniprot id: A0A3P8V4H8
names: Subcellular Location Annotation
messages: Membrane

244447:tmem201
gene id: 244447:tmem201
uniprot id: A0A3P8V794
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM201 family.
messages: Membrane
messages: Nucleus inner membrane

244447:LOC103397877
gene id: 244447:LOC103397877
uniprot id: A0A3P8WXC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

244447:arrdc2
gene id: 244447:arrdc2
uniprot id: A0A3P8WD45
uniprot id: A0A3P8WL45
names: Similarity
messages: Belongs to the arrestin family.

244447:mis18a
gene id: 244447:mis18a
uniprot id: A0A3P8WYS1
names: Function
names: Subcellular Location Annotation
messages: Required for recruitment of CENPA to centromeres and normal chromosome segregation during mitosis.
messages: centromere

244447:LOC103394264
gene id: 244447:LOC103394264
uniprot id: A0A3P8WBG5
names: Similarity
messages: Belongs to the peptidase C1 family.

244447:ccnq
gene id: 244447:ccnq
uniprot id: A0A3P8URZ2
names: Similarity
messages: Belongs to the cyclin family. Cyclin AB subfamily.
messages: Belongs to the cyclin family. Cyclin-like FAM58 subfamily.

244447:LOC103378738
gene id: 244447:LOC103378738
uniprot id: A0A3P8UQZ7
names: Similarity
messages: Belongs to the MARCKS family.

244447:pfdn1
gene id: 244447:pfdn1
uniprot id: A0A3P8VDG1
names: Similarity
messages: Belongs to the prefoldin subunit beta family.

244447:sec22c
gene id: 244447:sec22c
uniprot id: A0A3P8WS98
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Endoplasmic reticulum membrane
messages: May be involved in vesicle transport between the ER and the Golgi complex.
messages: Membrane

244447:ddost
gene id: 244447:ddost
uniprot id: A0A3P8UWH2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DDOST 48 kDa subunit family.
messages: Component of the oligosaccharyltransferase (OST) complex.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER).

244447:smo
gene id: 244447:smo
uniprot id: A0A3P8VM23
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor Fz/Smo family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

244447:fam126b
gene id: 244447:fam126b
uniprot id: A0A3P8VS48
uniprot id: A0A3P8VUQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM126 family.
messages: Cell membrane
messages: Membrane
messages: cytosol

244447:acss2
gene id: 244447:acss2
uniprot id: A0A3P8UJX5
uniprot id: A0A3P8UKY6
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

244447:slitrk6
gene id: 244447:slitrk6
uniprot id: A0A3P8VJN4
names: Similarity
messages: Belongs to the SLITRK family.

244447:elf4
gene id: 244447:elf4
uniprot id: A0A3P8UME2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

244447:nit1
gene id: 244447:nit1
uniprot id: A0A3P8UBG4
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

244447:LOC103397092
gene id: 244447:LOC103397092
uniprot id: A0A3P8VUL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GOLM family.
messages: Membrane

244447:LOC103394439
gene id: 244447:LOC103394439
uniprot id: A0A3P8WPJ3
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

244447:LOC103386560
gene id: 244447:LOC103386560
uniprot id: A0A3P8WCE9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.
messages: Cell membrane
messages: Membrane
messages: Proton-coupled monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and isoleucine, and the ketone bodies acetoacetate, beta-hydroxybutyrate and acetate. Depending on the tissue and on cicumstances, mediates the import or export of lactic acid and ketone bodies. Required for normal nutrient assimilation, increase of white adipose tissue and body weight gain when on a high-fat diet. Plays a role in cellular responses to a high-fat diet by modulating the cellular levels of lactate and pyruvate, small molecules that contribute to the regulation of central metabolic pathways and insulin secretion, with concomitant effects on plasma insulin levels and blood glucose homeostasis.

244447:kcng4
gene id: 244447:kcng4
uniprot id: A0A3P8X1V3
names: Subcellular Location Annotation
messages: Membrane

244447:LOC103380120
gene id: 244447:LOC103380120
uniprot id: A0A3P8UU26
names: Similarity
messages: Belongs to the prickle / espinas / testin family.

244447:xrcc5
gene id: 244447:xrcc5
uniprot id: A0A3P8VQN3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ku80 family.
messages: Nucleus
messages: Single-stranded DNA-dependent ATP-dependent helicase.

244447:LOC103398532
gene id: 244447:LOC103398532
uniprot id: A0A3P8UFT1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

244447:LOC103399961
gene id: 244447:LOC103399961
uniprot id: A0A3P8UT55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

244447:adcy6
gene id: 244447:adcy6
uniprot id: A0A3P8X1F5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Binds 2 magnesium ions per subunit. Is also active with manganese (in vitro).
messages: Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.
messages: Membrane

244447:atxn1
gene id: 244447:atxn1
uniprot id: A0A3P8WQ60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATXN1 family.
messages: Nucleus

244447:LOC103397673
gene id: 244447:LOC103397673
uniprot id: A0A3P8WJ32
uniprot id: A0A3P8WS68
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ephrin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

244447:man2c1
gene id: 244447:man2c1
uniprot id: A0A3P8US80
names: Similarity
messages: Belongs to the glycosyl hydrolase 38 family.

244447:LOC103377906
gene id: 244447:LOC103377906
uniprot id: A0A3P8V4L1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

244447:kiaa1024
gene id: 244447:kiaa1024
uniprot id: A0A3P8VB51
names: Similarity
messages: Belongs to the MINAR family.

244447:LOC103391350
gene id: 244447:LOC103391350
uniprot id: A0A3P8WL80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIG1 family.
messages: Membrane

244447:LOC103389549
gene id: 244447:LOC103389549
uniprot id: A0A3P8V6W5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type I cytokine receptor family. Type 1 subfamily.
messages: Membrane
messages: The WSXWS motif appears to be necessary for proper protein folding and thereby efficient intracellular transport and cell-surface receptor binding.
messages: The box 1 motif is required for JAK interaction and/or activation.
messages: This is a receptor for the anterior pituitary hormone prolactin.

244447:pptc7
gene id: 244447:pptc7
uniprot id: A0A3P8VSJ2
names: Similarity
messages: Belongs to the PP2C family.

244447:rab4a
gene id: 244447:rab4a
uniprot id: A0A3P8UD59
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Cell membrane
messages: Protein transport.

244447:LOC103393960
gene id: 244447:LOC103393960
uniprot id: A0A3P8UI24
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

244447:sptan1
gene id: 244447:sptan1
uniprot id: A0A3P8UIV6
uniprot id: A0A3P8US10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the spectrin family.
messages: cell cortex
messages: cytoskeleton

244447:LOC103392203
gene id: 244447:LOC103392203
uniprot id: A0A3P8W132
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM41 family.
messages: Membrane

244447:hcrtr2
gene id: 244447:hcrtr2
uniprot id: A0A3P8VU94
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

244447:pdgfrl
gene id: 244447:pdgfrl
uniprot id: A0A3P8WV54
names: Subcellular Location Annotation
names: Subunit
messages: Forms a complex composed of PDGFRL, TNK2 and GRB2.
messages: Secreted

244447:tpd52l2
gene id: 244447:tpd52l2
uniprot id: A0A3P8VMI9
names: Similarity
messages: Belongs to the TPD52 family.

244447:aplp2
gene id: 244447:aplp2
uniprot id: A0A3P8V6C3
uniprot id: A0A3P8V9Y6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the APP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

244447:LOC103391315
gene id: 244447:LOC103391315
uniprot id: A0A3P8WM60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

244447:atpaf1
gene id: 244447:atpaf1
uniprot id: A0A3P8ULE0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP11 family.
messages: Mitochondrion

244447:mitf
gene id: 244447:mitf
uniprot id: A0A3P8WQV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MiT/TFE family.
messages: Nucleus

244447:il1rapl1
gene id: 244447:il1rapl1
uniprot id: A0A3P8V3I3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the interleukin-1 receptor family.
messages: Membrane

244447:naprt
gene id: 244447:naprt
uniprot id: A0A3P8UTS6
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

244447:zw10
gene id: 244447:zw10
uniprot id: A0A3P8VKD4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZW10 family.
messages: kinetochore

244447:LOC103379028
gene id: 244447:LOC103379028
uniprot id: A0A3P8VFC2
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

244447:cfl1
gene id: 244447:cfl1
uniprot id: A0A3P8UZM8
names: Similarity
messages: Belongs to the actin-binding proteins ADF family.

244447:LOC103394606
gene id: 244447:LOC103394606
uniprot id: A0A3P8VCQ2
names: Similarity
messages: Belongs to the NDRG family.

244447:cep76
gene id: 244447:cep76
uniprot id: A0A3P8W0C6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CEP76 family.
messages: Centrosomal protein involved in regulation of centriole duplication. Required to limit centriole duplication to once per cell cycle by preventing centriole reduplication.
messages: centriole

244447:nr4a3
gene id: 244447:nr4a3
uniprot id: A0A3P8UK00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

244447:LOC103385266
gene id: 244447:LOC103385266
uniprot id: A0A3P8WPC6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the plexin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

244447:cnot10
gene id: 244447:cnot10
uniprot id: A0A3P8VV36
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CNOT10 family.
messages: Component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation.
messages: Cytoplasm
messages: Nucleus

244447:LOC103388835
gene id: 244447:LOC103388835
uniprot id: A0A3P8VX55
uniprot id: A0A3P8VX63
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

244447:slc1a1
gene id: 244447:slc1a1
uniprot id: A0A3P8WQD2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

244447:LOC103398145
gene id: 244447:LOC103398145
uniprot id: A0A3P8VXL5
uniprot id: A0A3P8W0A4
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

244447:LOC103386341
gene id: 244447:LOC103386341
uniprot id: A0A3P8VN46
names: Similarity
names: Subunit
messages: Belongs to the phosphatase and actin regulator family.
messages: Binds PPP1CA and actin.

244447:cd55
gene id: 244447:cd55
uniprot id: A0A3P8WG37
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

244447:LOC103395363
gene id: 244447:LOC103395363
uniprot id: A0A3P8WI06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC35F solute transporter family.
messages: Membrane

244447:zyg11b
gene id: 244447:zyg11b
uniprot id: A0A3P8V8Q3
names: Similarity
messages: Belongs to the zyg-11 family.

244447:LOC103385597
gene id: 244447:LOC103385597
uniprot id: A0A3P8X3J7
names: Similarity
messages: Belongs to the PPDPF family.

244447:LOC103398280
gene id: 244447:LOC103398280
uniprot id: A0A3P8WGE0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TDE1 family.
messages: Cell membrane
messages: Membrane

244447:LOC103397689
gene id: 244447:LOC103397689
uniprot id: A0A3P8WN56
uniprot id: A5JPX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR5 subfamily.
messages: Nucleus

244447:LOC103384726
gene id: 244447:LOC103384726
uniprot id: A0A3P8UX81
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.

244447:LOC103377856
gene id: 244447:LOC103377856
uniprot id: A0A3P8V434
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LRRC8 family.
messages: Cell membrane
messages: Membrane

244447:slc35b2
gene id: 244447:slc35b2
uniprot id: A0A3P8X007
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide-sugar transporter family. SLC35B subfamily.
messages: Membrane

244447:sbds
gene id: 244447:sbds
uniprot id: A0A3P8V775
names: Function
names: Similarity
messages: Belongs to the SDO1/SBDS family.
messages: Required for the assembly of mature ribosomes and ribosome biogenesis. Together with EFL1, triggers the GTP-dependent release of EIF6 from 60S pre-ribosomes in the cytoplasm, thereby activating ribosomes for translation competence by allowing 80S ribosome assembly and facilitating EIF6 recycling to the nucleus, where it is required for 60S rRNA processing and nuclear export. Required for normal levels of protein synthesis. May play a role in cellular stress resistance. May play a role in cellular response to DNA damage. May play a role in cell proliferation.

244447:LOC103378180
gene id: 244447:LOC103378180
uniprot id: A0A3P8UNU4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase inhibitor family.
messages: Endogenous F(1)F(o)-ATPase inhibitor limiting ATP depletion when the mitochondrial membrane potential falls below a threshold and the F(1)F(o)-ATP synthase starts hydrolyzing ATP to pump protons out of the mitochondrial matrix. Required to avoid the consumption of cellular ATP when the F(1)F(o)-ATP synthase enzyme acts as an ATP hydrolase.
messages: Forms an alpha-helical dimer with monomers associated via an antiparallel alpha-helical coiled coil, leaving each N-terminal inhibitory region accessible for interaction with an F1 catalytic domain. The inhibitory N-terminal region binds the alpha(ADP-bound)-beta(ADP-bound) (ATP5F1A-ATP5F1B) interface of F1-ATPase, and also contact the central gamma subunit (ATP5F1C). This dimeric state is favored by pH values below 7.0, and at higher values the dimers associate to form inactive homotetramer, where the inhibitory region is occluded, masking its inhibitory activity.
messages: Homodimer; represents the active form and is present at a pH value below 6.5. Homotetramer; represents the inactive form and is present at a pH value above 7.0.
messages: Indirectly acts as a regulator of heme synthesis in erythroid tissues: regulates heme synthesis by modulating the mitochondrial pH and redox potential, allowing fech to efficiently catalyze the incorporation of iron into protoporphyrin IX to produce heme.
messages: Mitochondrion

244447:eif3h
gene id: 244447:eif3h
uniprot id: A0A3P8VMU6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit H family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
messages: Cytoplasm

244447:smim19
gene id: 244447:smim19
uniprot id: A0A3P8W4D7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMIM19 family.
messages: Membrane

244447:c6h11orf58
gene id: 244447:c6h11orf58
uniprot id: A0A3P8UIB6
names: Similarity
messages: Belongs to the SMAP family.

244447:LOC103391188
gene id: 244447:LOC103391188
uniprot id: A0A3P8WBG8
names: Subcellular Location Annotation
messages: Membrane

244447:LOC103385672
gene id: 244447:LOC103385672
uniprot id: A0A3P8X4I0
names: Subcellular Location Annotation
messages: Nucleus

244447:rpl9
gene id: 244447:rpl9
uniprot id: A0A3P8UZ20
names: Similarity
messages: Belongs to the universal ribosomal protein uL6 family.

244447:LOC103388975
gene id: 244447:LOC103388975
uniprot id: A0A3P8WDC4
names: Similarity
messages: Belongs to the FAM110 family.

244447:shroom4
gene id: 244447:shroom4
uniprot id: A0A3P8UEH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the shroom family.
messages: cytoskeleton

244447:erbb4
gene id: 244447:erbb4
uniprot id: A0A3P8V3S0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. EGF receptor subfamily.
messages: Membrane

244447:echdc1
gene id: 244447:echdc1
uniprot id: A0A3P8VP07
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

244447:LOC103388353
gene id: 244447:LOC103388353
uniprot id: A0A3P8V0H5
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

244447:LOC103380482
gene id: 244447:LOC103380482
uniprot id: A0A3P8VXM7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endosulfine family.
messages: Cytoplasm
messages: Protein phosphatase inhibitor that specifically inhibits protein phosphatase 2A (PP2A) during mitosis.

244447:plg
gene id: 244447:plg
uniprot id: A0A3P8V360
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1 family. Plasminogen subfamily.
messages: Converted into plasmin by plasminogen activators, both plasminogen and its activator being bound to fibrin.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated by CSPG4. Binds to cells.
messages: extracellular space

244447:LOC103396975
gene id: 244447:LOC103396975
uniprot id: A0A3P8VJQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

244447:LOC103391436
gene id: 244447:LOC103391436
uniprot id: A0A3P8W580
names: Similarity
messages: Belongs to the mab-21 family.

244447:me2
gene id: 244447:me2
uniprot id: A0A3P8WH03
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

244447:cnot6l
gene id: 244447:cnot6l
uniprot id: A0A3P8W328
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCR4/nocturin family.
messages: Cytoplasm
messages: Nucleus

244447:mapk8
gene id: 244447:mapk8
uniprot id: A0A3P8WYS2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.
messages: Cytoplasm
messages: Responds to activation by environmental stress and pro-inflammatory cytokines by phosphorylating a number of transcription factors, and thus regulates transcriptional activity.

244447:LOC103380785
gene id: 244447:LOC103380785
uniprot id: A0A3P8WVU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POU transcription factor family. Class-3 subfamily.
messages: Nucleus

244447:arl14
gene id: 244447:arl14
uniprot id: A0A3P8WRD0
names: Similarity
messages: Belongs to the small GTPase superfamily. Arf family.

244447:abhd16a
gene id: 244447:abhd16a
uniprot id: A0A3P8WVW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AB hydrolase superfamily. ABHD16 family.
messages: Membrane

244447:abcb6
gene id: 244447:abcb6
uniprot id: A0A3P8VPY2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. ABCB family. Heavy Metal importer (TC 3.A.1.210) subfamily.
messages: Early endosome membrane
messages: Endosome membrane
messages: Golgi apparatus membrane
messages: Homodimer.
messages: Late endosome membrane
messages: Lysosome membrane
messages: Melanosome membrane
messages: Membrane
messages: Mitochondrion outer membrane
messages: extracellular exosome
messages: multivesicular body membrane

244447:arrdc3
gene id: 244447:arrdc3
uniprot id: A0A3P8WEU4
names: Similarity
messages: Belongs to the arrestin family.

244447:LOC103382384
gene id: 244447:LOC103382384
uniprot id: A0A3P8UBB0
names: Subcellular Location Annotation
messages: Nucleus

244447:LOC103384992
gene id: 244447:LOC103384992
uniprot id: A0A3P8V0T8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

244447:LOC103385014
gene id: 244447:LOC103385014
uniprot id: A0A3P8V2J4
names: Similarity
messages: Belongs to the TCF/LEF family.

244447:rplp0
gene id: 244447:rplp0
uniprot id: A0A3P8V986
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Ribosomal protein P0 is the functional equivalent of E.coli protein L10.

244447:LOC103378552
gene id: 244447:LOC103378552
uniprot id: A0A3P8WSY5
names: Similarity
messages: Belongs to the folate receptor family.

244447:nxpe3
gene id: 244447:nxpe3
uniprot id: A0A3P8USV3
names: Similarity
messages: Belongs to the NXPE family.

244447:pi4k2b
gene id: 244447:pi4k2b
uniprot id: A0A3P8WB49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PI3/PI4-kinase family. Type II PI4K subfamily.
messages: Membrane

244447:LOC103379158
gene id: 244447:LOC103379158
uniprot id: A0A3P8UUQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DP1 family.
messages: Membrane

244447:LOC103376746
gene id: 244447:LOC103376746
uniprot id: A0A3P8VB35
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

244447:atg5
gene id: 244447:atg5
uniprot id: A0A3P8VPG2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATG5 family.
messages: Conjugated with ATG12.
messages: Involved in autophagic vesicle formation. Conjugation with ATG12, through a ubiquitin-like conjugating system involving ATG7 as an E1-like activating enzyme and ATG10 as an E2-like conjugating enzyme, is essential for its function. The ATG12-ATG5 conjugate acts as an E3-like enzyme which is required for lipidation of ATG8 family proteins and their association to the vesicle membranes. Involved in mitochondrial quality control after oxidative damage, and in subsequent cellular longevity. Plays a critical role in multiple aspects of lymphocyte development and is essential for both B and T lymphocyte survival and proliferation. Required for optimal processing and presentation of antigens for MHC II. Involved in the maintenance of axon morphology and membrane structures, as well as in normal adipocyte differentiation. Promotes primary ciliogenesis through removal of OFD1 from centriolar satellites and degradation of IFT20 via the autophagic pathway.
messages: May play an important role in the apoptotic process, possibly within the modified cytoskeleton. Its expression is a relatively late event in the apoptotic process, occurring downstream of caspase activity. Plays a crucial role in IFN-gamma-induced autophagic cell death by interacting with FADD.
messages: Preautophagosomal structure membrane

244447:LOC103386984
gene id: 244447:LOC103386984
uniprot id: A0A3P8UPF3
uniprot id: A0A3P8UPG1
names: Similarity
messages: Belongs to the OSBP family.

244447:oxct1
gene id: 244447:oxct1
uniprot id: A0A3P8WIF0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 3-oxoacid CoA-transferase family.
messages: Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.
messages: Mitochondrion

244447:enpp6
gene id: 244447:enpp6
uniprot id: A0A3P8WYR7
names: Similarity
messages: Belongs to the nucleotide pyrophosphatase/phosphodiesterase family.

244447:slc49a3
gene id: 244447:slc49a3
uniprot id: A0A3P8W115
names: Subcellular Location Annotation
messages: Membrane

244447:LOC103384854
gene id: 244447:LOC103384854
uniprot id: A0A3P8UXI5
names: Subcellular Location Annotation
messages: nucleolus

244447:enpep
gene id: 244447:enpep
uniprot id: A0A3P8UWF2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homodimer; disulfide-linked.

244447:LOC103395053
gene id: 244447:LOC103395053
uniprot id: A0A3P8WYY7
names: Similarity
messages: Belongs to the heat shock protein 70 family.

244447:LOC103395982
gene id: 244447:LOC103395982
uniprot id: A0A3P8WG19
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRP38 family.
messages: May be required for pre-mRNA splicing.
messages: Nucleus

244447:LOC103393075
gene id: 244447:LOC103393075
uniprot id: A0A3P8WGJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

244447:eif4a3
gene id: 244447:eif4a3
uniprot id: A0A3P8X1C6
names: Similarity
messages: Belongs to the DEAD box helicase family.

244447:sbno1
gene id: 244447:sbno1
uniprot id: A0A3P8VWF3
names: Similarity
messages: Belongs to the SBNO family.

244447:LOC103382719
gene id: 244447:LOC103382719
uniprot id: A0A3P8VD16
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERGIC family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Golgi apparatus membrane
messages: Plays a role in transport between endoplasmic reticulum and Golgi.

244447:LOC103382554
gene id: 244447:LOC103382554
uniprot id: A0A3P8UUP2
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

244447:tmem208
gene id: 244447:tmem208
uniprot id: A0A3P8VZN0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM208 family.
messages: Endoplasmic reticulum membrane
messages: May function as a negative regulator of endoplasmic reticulum-stress induced autophagy.
messages: Membrane

244447:ninj1
gene id: 244447:ninj1
uniprot id: A0A3P8UHJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ninjurin family.
messages: Membrane

244447:LOC103391250
gene id: 244447:LOC103391250
uniprot id: A0A3P8WFT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

244447:LOC103389207
gene id: 244447:LOC103389207
uniprot id: A0A3P8WSX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NTE family.
messages: Endoplasmic reticulum membrane
messages: Membrane

244447:manea
gene id: 244447:manea
uniprot id: A0A3P8URB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 99 family.
messages: Golgi apparatus membrane
messages: Membrane

244447:dag1
gene id: 244447:dag1
uniprot id: A0A3P8W8A2
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane
messages: The dystroglycan complex is involved in a number of processes including laminin and basement membrane assembly, sarcolemmal stability, cell survival, peripheral nerve myelination, nodal structure, cell migration, and epithelial polarization.
messages: Transmembrane protein that plays important roles in connecting the extracellular matrix to the cytoskeleton. Acts as a cell adhesion receptor in both muscle and non-muscle tissues. Receptor for both DMD and UTRN and, through these interactions, scaffolds axin to the cytoskeleton. Also functions in cell adhesion-mediated signaling and implicated in cell polarity.
messages: extracellular space
messages: nucleoplasm
messages: sarcolemma

244447:klhl40
gene id: 244447:klhl40
uniprot id: A0A3P8WM68
names: Similarity
names: Subcellular Location Annotation
messages: A band
messages: Belongs to the KLHL40 family.
messages: I band

244447:LOC103382779
gene id: 244447:LOC103382779
uniprot id: A0A3P8VM45
names: Subcellular Location Annotation
messages: Membrane

244447:pes1
gene id: 244447:pes1
uniprot id: A0A3P8WM63
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pescadillo family.
messages: Component of the PeBoW complex, composed of BOP1, PES1 and WDR12. Within the PeBoW complex BOP1 interacts directly with PES1 and WDR12. The PeBoW complex also associates with the 66S pre-ribosome.
messages: Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.
messages: nucleolus
messages: nucleoplasm

244447:LOC103385160
gene id: 244447:LOC103385160
uniprot id: A0A3P8VK84
names: Similarity
messages: Belongs to the PPDPF family.

244447:zdhhc15
gene id: 244447:zdhhc15
uniprot id: A0A3P8WCT2
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

244447:tex10
gene id: 244447:tex10
uniprot id: A0A3P8UIN1
names: Similarity
messages: Belongs to the IPI1/TEX10 family.

244447:LOC103383486
gene id: 244447:LOC103383486
uniprot id: A0A3P8UNR4
names: Similarity
messages: Belongs to the TAPR1 family.

244447:rpp30
gene id: 244447:rpp30
uniprot id: A0A3P8UPR1
names: Similarity
messages: Belongs to the eukaryotic/archaeal RNase P protein component 3 family.

244447:LOC103387816
gene id: 244447:LOC103387816
uniprot id: A0A3P8WVY1
names: Function
names: Similarity
messages: Belongs to the cytochrome c oxidase subunit 6B.
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.

244447:rpl7l1
gene id: 244447:rpl7l1
uniprot id: A0A3P8WTA6
names: Similarity
messages: Belongs to the universal ribosomal protein uL30 family.

244447:cct8
gene id: 244447:cct8
uniprot id: A0A3P8VJE9
uniprot id: A0A3P8VM08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCP-1 chaperonin family.
messages: cilium basal body

244447:LOC103378040
gene id: 244447:LOC103378040
uniprot id: A0A3P8VDR4
names: Subcellular Location Annotation
messages: Mitochondrion

244447:LOC103398324
gene id: 244447:LOC103398324
uniprot id: A0A3P8WUR6
names: Function
names: Similarity
messages: Belongs to the vestigial family.
messages: May act as a specific coactivator for the mammalian TEFs.

244447:bcl9l
gene id: 244447:bcl9l
uniprot id: A0A3P8VE66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BCL9 family.
messages: Nucleus

244447:cemip2
gene id: 244447:cemip2
uniprot id: A0A3P8W7L9
names: Similarity
messages: Belongs to the CEMIP family.

244447:gtf2e2
gene id: 244447:gtf2e2
uniprot id: A0A3P8VAP3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TFIIE beta subunit family.
messages: Nucleus
messages: Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase.
messages: Tetramer of two alpha and two beta chains.

244447:LOC103386601
gene id: 244447:LOC103386601
uniprot id: A0A3P8WLR2
uniprot id: A0A3P8WP62
names: Subcellular Location Annotation
messages: Cell membrane
messages: Cytoplasmic vesicle membrane
messages: Membrane
messages: cytosol
messages: ruffle membrane
messages: synaptosome

244447:LOC103380016
gene id: 244447:LOC103380016
uniprot id: A0A3P8UY51
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: A pair of annexin repeats may form one binding site for calcium and phospholipid.
messages: Belongs to the annexin family.
messages: Membrane
messages: basement membrane

244447:klhl36
gene id: 244447:klhl36
uniprot id: A0A3P8UJJ3
names: Function
messages: Probable substrate-specific adapter of an E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.

244447:LOC103391702
gene id: 244447:LOC103391702
uniprot id: A0A3P8V0Q3
names: Similarity
messages: Belongs to the IUNH family.

244447:alx3
gene id: 244447:alx3
uniprot id: A0A3P8UWU2
names: Subcellular Location Annotation
messages: Nucleus

244447:vps54
gene id: 244447:vps54
uniprot id: A0A3P8VK38
names: Similarity
messages: Belongs to the VPS54 family.

244447:mdm1
gene id: 244447:mdm1
uniprot id: A0A3P8V207
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MDM1 family.
messages: Nucleus
messages: centriole

244447:LOC103395272
gene id: 244447:LOC103395272
uniprot id: A0A3P8W4H7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.
messages: Cytoplasm
messages: Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, neuronal growth cone collapse and cell migration.
messages: growth cone

244447:btaf1
gene id: 244447:btaf1
uniprot id: A0A3P8VC51
names: Subcellular Location Annotation
messages: Nucleus

244447:csrnp1
gene id: 244447:csrnp1
uniprot id: A0A3P8WKP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AXUD1 family.
messages: Nucleus

244447:ociad1
gene id: 244447:ociad1
uniprot id: A0A3P8VIP2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OCIAD1 family.
messages: Endosome
messages: Interacts with STAT3.
messages: Maintains stem cell potency. Increases STAT3 phosphorylation and controls ERK phosphorylation. May act as a scaffold, increasing STAT3 recruitment onto endosomes.
messages: The OCIA domain is necessary and sufficient for endosomal localization.

244447:hyls1
gene id: 244447:hyls1
uniprot id: A0A3P8WZ50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HYLS1 family.
messages: centriole
messages: cilium

244447:ptgis
gene id: 244447:ptgis
uniprot id: A0A3P8UPX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Endoplasmic reticulum membrane

244447:ist1
gene id: 244447:ist1
uniprot id: A0A3P8UI06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IST1 family.
messages: Cytoplasmic vesicle
messages: Nucleus envelope

244447:asl
gene id: 244447:asl
uniprot id: A0A3P8WRG2
names: Similarity
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.

244447:ccr7
gene id: 244447:ccr7
uniprot id: A0A3P8W519
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Early endosome
messages: Endosome
messages: Membrane

244447:LOC103378807
gene id: 244447:LOC103378807
uniprot id: A0A3P8UN88
names: Similarity
messages: Belongs to the CDI family.

244447:unc50
gene id: 244447:unc50
uniprot id: A0A3P8UJK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the unc-50 family.
messages: Membrane
messages: Nucleus inner membrane

244447:fgf23
gene id: 244447:fgf23
uniprot id: A0A3P8VC34
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

244447:slc25a26
gene id: 244447:slc25a26
uniprot id: A0A3P8V228
uniprot id: A0A3P8V3C5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

244447:ric8a
gene id: 244447:ric8a
uniprot id: A0A3P8X4X7
uniprot id: A0A3P8X5V8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the synembryn family.
messages: Cytoplasm
messages: Guanine nucleotide exchange factor (GEF), which can activate some, but not all, G-alpha proteins by exchanging bound GDP for free GTP.
messages: Interacts with some GDP-bound G alpha proteins. Does not interact with G-alpha proteins when they are in complex with subunits beta and gamma.

244447:phlda2
gene id: 244447:phlda2
uniprot id: A0A3P8VKE6
names: Subcellular Location Annotation
messages: Cytoplasm

244447:wars2
gene id: 244447:wars2
uniprot id: A0A3P8VGI9
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

244447:lbh
gene id: 244447:lbh
uniprot id: A0A3P8USY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LBH family.
messages: Cytoplasm
messages: Nucleus

244447:LOC103398273
gene id: 244447:LOC103398273
uniprot id: A0A3P8WIB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the repulsive guidance molecule (RGM) family.
messages: Cell membrane
messages: Membrane

244447:tmem237
gene id: 244447:tmem237
uniprot id: A0A3P8V6U2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM237 family.
messages: Component of the transition zone in primary cilia. Required for ciliogenesis.
messages: Membrane
messages: cilium

244447:LOC103396333
gene id: 244447:LOC103396333
uniprot id: A0A3P8VYS0
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.
messages: Membrane
messages: desmosome

244447:LOC103392022
gene id: 244447:LOC103392022
uniprot id: A0A3P8VLS7
names: Similarity
messages: Belongs to the SLITRK family.

244447:tyw3
gene id: 244447:tyw3
uniprot id: A0A3P8X075
names: Function
names: Similarity
messages: Belongs to the TYW3 family.
messages: Probable S-adenosyl-L-methionine-dependent methyltransferase that acts as a component of the wybutosine biosynthesis pathway. Wybutosine is a hyper modified guanosine with a tricyclic base found at the 3'-position adjacent to the anticodon of eukaryotic phenylalanine tRNA.

244447:LOC103377068
gene id: 244447:LOC103377068
uniprot id: A0A3P8W1T5
names: Similarity
messages: Belongs to the CCDC90 family.

244447:LOC103386087
gene id: 244447:LOC103386087
uniprot id: A0A3P8UV75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM183 family.
messages: Membrane

244447:mettl4
gene id: 244447:mettl4
uniprot id: A0A3P8UJS2
names: Similarity
messages: Belongs to the MT-A70-like family.

244447:ccnl1
gene id: 244447:ccnl1
uniprot id: A0A3P8UHI7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cyclin family. Cyclin AB subfamily.
messages: Belongs to the cyclin family. Cyclin L subfamily.
messages: Essential for the control of the cell cycle at the G2/M (mitosis) transition.
messages: Interacts with the CDK1 protein kinase to form a serine/threonine kinase holoenzyme complex also known as maturation promoting factor (MPF). The cyclin subunit imparts substrate specificity to the complex.
messages: Nucleus speckle
messages: nucleoplasm

244447:LOC103394755
gene id: 244447:LOC103394755
uniprot id: A0A3P8VTD3
names: Subcellular Location Annotation
messages: Membrane

244447:kpna4
gene id: 244447:kpna4
uniprot id: A0A3P8WMM2
names: Similarity
messages: Belongs to the importin alpha family.

244447:scpep1
gene id: 244447:scpep1
uniprot id: A0A3P8W5I0
names: Similarity
messages: Belongs to the peptidase S10 family.

244447:slc43a3
gene id: 244447:slc43a3
uniprot id: A0A3P8V7S9
names: Subcellular Location Annotation
messages: Membrane

244447:eogt
gene id: 244447:eogt
uniprot id: A0A3P8V0I3
names: Similarity
messages: Belongs to the glycosyltransferase 61 family.

244447:LOC103391028
gene id: 244447:LOC103391028
uniprot id: A0A3P8VS41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P33MONOX family.
messages: Cytoplasm

244447:LOC103385828
gene id: 244447:LOC103385828
uniprot id: A0A3P8UQ06
names: Similarity
messages: Belongs to the TEX28 family.

244447:LOC103389450
gene id: 244447:LOC103389450
uniprot id: T2B9L0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Membrane

244447:LOC103388381
gene id: 244447:LOC103388381
uniprot id: A0A3P8UXK5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

244447:LOC103377788
gene id: 244447:LOC103377788
uniprot id: A0A3P8UXE4
uniprot id: A0A3P8UXF2
names: Similarity
messages: Belongs to the peptidase C19 family.

244447:ereg
gene id: 244447:ereg
uniprot id: A0A3P8WYJ0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

244447:LOC103393635
gene id: 244447:LOC103393635
uniprot id: A0A3P8WF07
names: Similarity
messages: Belongs to the DNase I family.

244447:galnt11
gene id: 244447:galnt11
uniprot id: A0A3P8WWA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

244447:ubiad1
gene id: 244447:ubiad1
uniprot id: A0A3P8V3A2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family.
messages: Membrane

244447:trim36
gene id: 244447:trim36
uniprot id: A0A172PZL3
uniprot id: A0A3P8V897
names: Subcellular Location Annotation
messages: cytoskeleton

244447:anapc2
gene id: 244447:anapc2
uniprot id: A0A3P8VSY1
names: Similarity
messages: Belongs to the cullin family.

244447:nol12
gene id: 244447:nol12
uniprot id: A0A3P8V996
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRP17 family.
messages: nucleolus

244447:tlr3
gene id: 244447:tlr3
uniprot id: A0A3P8WBG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Toll-like receptor family.
messages: Membrane

244447:parpbp
gene id: 244447:parpbp
uniprot id: A0A3P8V4D8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PARI family.
messages: Cytoplasm
messages: Nucleus

244447:dsel
gene id: 244447:dsel
uniprot id: A0A3P8WZ81
names: Similarity
messages: Belongs to the dermatan-sulfate isomerase family.

244447:katnal2
gene id: 244447:katnal2
uniprot id: A0A3P8WX37
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family. Katanin p60 subunit A1 subfamily. A-like 2 sub-subfamily.
messages: Cytoplasm
messages: Severs microtubules in vitro in an ATP-dependent manner. This activity may promote rapid reorganization of cellular microtubule arrays.
messages: cytoskeleton
messages: spindle
messages: spindle pole

244447:ppfia4
gene id: 244447:ppfia4
uniprot id: A0A3P8UZ79
names: Similarity
messages: Belongs to the liprin family. Liprin-alpha subfamily.

244447:LOC103395960
gene id: 244447:LOC103395960
uniprot id: A0A3P8W8Y0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCC4/mau-2 family.
messages: nucleoplasm

244447:LOC103389958
gene id: 244447:LOC103389958
uniprot id: A0A3P8VWS2
names: Subcellular Location Annotation
messages: Chromosome
messages: Nucleus

244447:LOC103379893
gene id: 244447:LOC103379893
uniprot id: A0A3P8V6X4
names: Similarity
messages: Belongs to the glycosyltransferase 92 family.

244447:LOC103378666
gene id: 244447:LOC103378666
uniprot id: A0A3P8UE87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

244447:rfx1
gene id: 244447:rfx1
uniprot id: A0A3P8W0H5
names: Subcellular Location Annotation
messages: Nucleus

244447:faah2
gene id: 244447:faah2
uniprot id: A0A3P8V1Q3
names: Similarity
messages: Belongs to the amidase family.

244447:crabp1
gene id: 244447:crabp1
uniprot id: A0A3P8USL2
names: Function
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
messages: Cytosolic CRABPs may regulate the access of retinoic acid to the nuclear retinoic acid receptors.

244447:KEH01 p01
gene id: 244447:KEH01_p01
uniprot id: C5H0G5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome b family.
messages: Binds 2 heme groups non-covalently.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
messages: Membrane
messages: Mitochondrion inner membrane

244447:LOC103394908
gene id: 244447:LOC103394908
uniprot id: A0A3P8WDI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

244447:LOC103387031
gene id: 244447:LOC103387031
uniprot id: A0A3P8URC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the serine esterase family.
messages: Endoplasmic reticulum membrane
messages: Membrane

244447:LOC103378077
gene id: 244447:LOC103378077
uniprot id: A0A3P8VCW0
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

244447:atxn1l
gene id: 244447:atxn1l
uniprot id: A0A3P8UH45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATXN1 family.
messages: Nucleus

244447:tmem184c
gene id: 244447:tmem184c
uniprot id: A0A3P8UFM4
names: Subcellular Location Annotation
messages: Membrane

244447:cyr61
gene id: 244447:cyr61
uniprot id: A0A3P8WSF3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCN family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

244447:LOC103384198
gene id: 244447:LOC103384198
uniprot id: A0A3P8W6A1
names: Similarity
messages: Belongs to the TOM1 family.

244447:sfxn4
gene id: 244447:sfxn4
uniprot id: A0A3P8VKL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sideroflexin family.
messages: Membrane

244447:entpd2
gene id: 244447:entpd2
uniprot id: A0A3P8UIF4
names: Similarity
messages: Belongs to the GDA1/CD39 NTPase family.

244447:csrnp2
gene id: 244447:csrnp2
uniprot id: A0A3P8WE45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AXUD1 family.
messages: Nucleus

244447:LOC103379203
gene id: 244447:LOC103379203
uniprot id: A0A3P8VBC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anoctamin family.
messages: Membrane

244447:LOC103386454
gene id: 244447:LOC103386454
uniprot id: A0A3P8W154
names: Similarity
messages: Belongs to the copine family.

244447:nkx3-1
gene id: 244447:nkx3-1
uniprot id: A0A3P8W5I2
names: Subcellular Location Annotation
messages: Nucleus

244447:LOC103382243
gene id: 244447:LOC103382243
uniprot id: A0A3P8VYX6
names: Subcellular Location Annotation
messages: Nucleus

244447:galc
gene id: 244447:galc
uniprot id: A0A3P8WJC9
uniprot id: A0A3P8WM32
names: Similarity
messages: Belongs to the glycosyl hydrolase 59 family.

244447:lpar6
gene id: 244447:lpar6
uniprot id: A0A3P8V8X6
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

244447:glul
gene id: 244447:glul
uniprot id: A0A3P8WRA6
names: Similarity
messages: Belongs to the glutamine synthetase family.

244447:tmem256
gene id: 244447:tmem256
uniprot id: A0A3P8W289
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM256 family.
messages: Membrane

244447:zdhhc7
gene id: 244447:zdhhc7
uniprot id: A0A3P8VZU0
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

244447:LOC103386906
gene id: 244447:LOC103386906
uniprot id: A0A3P8UFN6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

244447:upf1
gene id: 244447:upf1
uniprot id: A0A3P8WKZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA2/NAM7 helicase family.
messages: Cytoplasm

244447:atp6v1a
gene id: 244447:atp6v1a
uniprot id: A0A3P8WIJ8
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.

244447:LOC103377655
gene id: 244447:LOC103377655
uniprot id: A0A3P8UNZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the P2X receptor family.
messages: Functional P2XRs are organized as homomeric and heteromeric trimers.
messages: Membrane
messages: Receptor for ATP that acts as a ligand-gated ion channel.

244447:LOC103396405
gene id: 244447:LOC103396405
uniprot id: A0A3P8VZ27
uniprot id: A0A3P8VZ32
names: Subcellular Location Annotation
messages: Membrane

244447:map3k5
gene id: 244447:map3k5
uniprot id: A0A3P8UYK6
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.

244447:tie1
gene id: 244447:tie1
uniprot id: A0A3P8WXE4
names: Caution
names: Subcellular Location Annotation
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

244447:tbca
gene id: 244447:tbca
uniprot id: A0A3P8W0H3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TBCA family.
messages: Supercomplex made of cofactors A to E. Cofactors A and D function by capturing and stabilizing tubulin in a quasi-native conformation. Cofactor E binds to the cofactor D-tubulin complex; interaction with cofactor C then causes the release of tubulin polypeptides that are committed to the native state.
messages: Tubulin-folding protein; involved in the early step of the tubulin folding pathway.
messages: cytoskeleton

244447:tmem178b
gene id: 244447:tmem178b
uniprot id: A0A3P8WCX9
names: Similarity
messages: Belongs to the TMEM178 family.

244447:LOC103394531
gene id: 244447:LOC103394531
uniprot id: A0A3P8VE15
names: Similarity
messages: Belongs to the S-100 family.

244447:sephs1
gene id: 244447:sephs1
uniprot id: A0A3P8V6A9
names: Function
messages: Synthesizes selenophosphate from selenide and ATP.

244447:LOC103393093
gene id: 244447:LOC103393093
uniprot id: A0A3P8WC70
uniprot id: A0A3P8WFA1
names: Similarity
messages: Belongs to the TOM1 family.

244447:LOC103394109
gene id: 244447:LOC103394109
uniprot id: A0A3P8W1A7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the E2F/DP family.
messages: Nucleus

244447:lars
gene id: 244447:lars
uniprot id: A0A3P8WD38
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

244447:slc50a1
gene id: 244447:slc50a1
uniprot id: A0A3P8URG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SWEET sugar transporter family.
messages: Membrane

244447:LOC103379687
gene id: 244447:LOC103379687
uniprot id: A0A3P8X6A1
names: Similarity
messages: Belongs to the ATG8 family.

244447:LOC103380165
gene id: 244447:LOC103380165
uniprot id: A0A3P8V450
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

244447:slc35b1
gene id: 244447:slc35b1
uniprot id: A0A3P8X6R5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide-sugar transporter family. SLC35B subfamily.
messages: Membrane

244447:LOC103389897
gene id: 244447:LOC103389897
uniprot id: A0A3P8VZI6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

244447:dis3l2
gene id: 244447:dis3l2
uniprot id: A0A3P8WP72
uniprot id: A0A3P8WR37
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5'-exoribonuclease that specifically recognizes RNAs polyuridylated at their 3' end and mediates their degradation. Component of an exosome-independent RNA degradation pathway that mediates degradation of both mRNAs and miRNAs that have been polyuridylated by a terminal uridylyltransferase. Essential for correct mitosis, and negatively regulates cell proliferation.
messages: Belongs to the RNR ribonuclease family. DIS3L2 subfamily.
messages: Cytoplasm
messages: P-body
messages: Specifically recognizes and binds polyuridylated RNAs via 3 RNA-binding regions (named U-zone 1, U-zone 2 and U-zone 3) that form an open funnel on one face of the catalytic domain, allowing RNA to navigate a path to the active site.

244447:LOC103391053
gene id: 244447:LOC103391053
uniprot id: A0A3P8VXM0
names: Subcellular Location Annotation
messages: Nucleus

244447:LOC103398250
gene id: 244447:LOC103398250
uniprot id: A0A3P8WBC7
names: Similarity
messages: Belongs to the GDNFR family.

244447:LOC103390991
gene id: 244447:LOC103390991
uniprot id: A0A3P8VRI9
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the SLC34A transporter family.
messages: Cell membrane
messages: Membrane

244447:kat6b
gene id: 244447:kat6b
uniprot id: A0A3P8VIG6
names: Similarity
messages: Belongs to the MYST (SAS/MOZ) family.

244447:LOC103385021
gene id: 244447:LOC103385021
uniprot id: A0A3P8V931
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

244447:pcyt2
gene id: 244447:pcyt2
uniprot id: A0A3P8VEP0
names: Similarity
messages: Belongs to the cytidylyltransferase family.

244447:tp53i11
gene id: 244447:tp53i11
uniprot id: A0A3P8W4A0
names: Subcellular Location Annotation
messages: Membrane

244447:LOC103377989
gene id: 244447:LOC103377989
uniprot id: A0A3P8V9P0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

244447:nxph4
gene id: 244447:nxph4
uniprot id: A0A3P8VS59
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neurexophilin family.
messages: May be signaling molecules that resemble neuropeptides.
messages: Secreted

244447:htr7
gene id: 244447:htr7
uniprot id: A0A3P8UM19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

244447:LOC103394607
gene id: 244447:LOC103394607
uniprot id: A0A3P8VIP0
names: Subcellular Location Annotation
messages: Nucleus

244447:tipin
gene id: 244447:tipin
uniprot id: A0A3P8VAQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSM3 family.
messages: Nucleus
messages: Plays an important role in the control of DNA replication and the maintenance of replication fork stability.

244447:slc48a1
gene id: 244447:slc48a1
uniprot id: A0A3P8WJ11
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HRG family.
messages: Endosome membrane
messages: Heme transporter that regulates intracellular heme availability through the endosomal or lysosomal compartment.
messages: Lysosome membrane
messages: Membrane

244447:dpy19l4
gene id: 244447:dpy19l4
uniprot id: A0A3P8VF53
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dpy-19 family.
messages: Membrane
messages: Probable C-mannosyltransferase that mediates C-mannosylation of tryptophan residues on target proteins.

244447:LOC103386619
gene id: 244447:LOC103386619
uniprot id: A0A3P8WRQ3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

244447:angptl4
gene id: 244447:angptl4
uniprot id: A0A3P8VY46
names: Subcellular Location Annotation
messages: Secreted

244447:dad1
gene id: 244447:dad1
uniprot id: A0A3P8WQK3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DAD/OST2 family.
messages: Component of the oligosaccharyltransferase (OST) complex.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity.

244447:LOC103395484
gene id: 244447:LOC103395484
uniprot id: A0A3P8WTQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Endosome membrane
messages: Membrane

244447:mpp6
gene id: 244447:mpp6
uniprot id: A0A3P8VV64
uniprot id: A0A3P8W3K2
names: Similarity
messages: Belongs to the MAGUK family.

244447:LOC103378257
gene id: 244447:LOC103378257
uniprot id: A0A3P8W9Y2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

244447:gpr4
gene id: 244447:gpr4
uniprot id: A0A3P8V177
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

244447:msra
gene id: 244447:msra
uniprot id: A0A3P8UVG1
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.

244447:gpn3
gene id: 244447:gpn3
uniprot id: A0A3P8UZD7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GPN-loop GTPase family.
messages: Binds to RNA polymerase II (RNAPII).
messages: Small GTPase required for proper localization of RNA polymerase II (RNAPII). May act at an RNAP assembly step prior to nuclear import.
messages: Small GTPase required for proper nuclear import of RNA polymerase II and III (RNAPII and RNAPIII). May act at an RNAP assembly step prior to nuclear import.

244447:LOC103396246
gene id: 244447:LOC103396246
uniprot id: A0A3P8WS53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

244447:igfbp2
gene id: 244447:igfbp2
uniprot id: A0A3P8V341
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

244447:trmt10c
gene id: 244447:trmt10c
uniprot id: A0A3P8VAX1
names: Subcellular Location Annotation
messages: mitochondrion nucleoid

244447:ldlrad3
gene id: 244447:ldlrad3
uniprot id: A0A3P8W422
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

244447:app
gene id: 244447:app
uniprot id: A0A3P8W1W0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the APP family.
messages: Cell membrane
messages: Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

244447:LOC103380828
gene id: 244447:LOC103380828
uniprot id: A0A3P8X4I2
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 4 family.

244447:syngr1
gene id: 244447:syngr1
uniprot id: A0A3P8UP58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptogyrin family.
messages: Membrane

244447:LOC103383092
gene id: 244447:LOC103383092
uniprot id: A0A3P8X390
names: Similarity
messages: Belongs to the CNOT2/3/5 family.

244447:asphd2
gene id: 244447:asphd2
uniprot id: A0A3P8WRY3
names: Similarity
messages: Belongs to the aspartyl/asparaginyl beta-hydroxylase family.

244447:cav2
gene id: 244447:cav2
uniprot id: A0A3P8X0W7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the caveolin family.
messages: Cell membrane
messages: Golgi apparatus membrane
messages: May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity.
messages: Membrane
messages: caveola

244447:nexmif
gene id: 244447:nexmif
uniprot id: A0A3P8W9P5
names: Subcellular Location Annotation
messages: Nucleus

244447:LOC103381604
gene id: 244447:LOC103381604
uniprot id: A0A3P8VMA5
names: Similarity
messages: Belongs to the TACO1 family.

244447:ergic1
gene id: 244447:ergic1
uniprot id: A0A3P8W6Z6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERGIC family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Golgi apparatus membrane
messages: Plays a role in transport between endoplasmic reticulum and Golgi.

244447:LOC103384861
gene id: 244447:LOC103384861
uniprot id: A0A3P8UYN1
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL22 family.

244447:LOC103393591
gene id: 244447:LOC103393591
uniprot id: A0A3P8W4C2
names: Similarity
messages: Belongs to the protein kinase superfamily.

244447:ptx3
gene id: 244447:ptx3
uniprot id: A0A3P8ULG3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

244447:anxa1
gene id: 244447:anxa1
uniprot id: A0A3P8WAJ7
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: A pair of annexin repeats may form one binding site for calcium and phospholipid.
messages: Basolateral cell membrane
messages: Belongs to the annexin family.
messages: Cell membrane
messages: Cytoplasm
messages: Lateral cell membrane
messages: Membrane
messages: Nucleus
messages: cilium

244447:LOC103383467
gene id: 244447:LOC103383467
uniprot id: A0A3P8UME4
names: Similarity
messages: Belongs to the peptidase C14A family.

244447:LOC103385782
gene id: 244447:LOC103385782
uniprot id: A0A3P8UIA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
messages: Membrane

244447:cdk5
gene id: 244447:cdk5
uniprot id: A0A3P8VSQ0
names: Similarity
messages: Belongs to the protein kinase superfamily.

244447:LOC103384405
gene id: 244447:LOC103384405
uniprot id: A0A3P8WPT8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the F-actin-capping protein alpha subunit family.
messages: F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.
messages: Heterodimer of an alpha and a beta subunit.

244447:LOC103377975
gene id: 244447:LOC103377975
uniprot id: A0A3P8VA42
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1 family.
messages: Degrades extracellular matrix.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

244447:LOC103390172
gene id: 244447:LOC103390172
uniprot id: A0A3P8WEI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRP4 family.
messages: Cytoplasm

244447:marveld3
gene id: 244447:marveld3
uniprot id: A0A3P8UHB3
names: Subcellular Location Annotation
messages: Membrane

244447:pah
gene id: 244447:pah
uniprot id: A0A3P8UXX2
names: Similarity
messages: Belongs to the biopterin-dependent aromatic amino acid hydroxylase family.

244447:LOC103394203
gene id: 244447:LOC103394203
uniprot id: A0A3P8W1Y8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

244447:hmgcll1
gene id: 244447:hmgcll1
uniprot id: A0A3P8VNS2
names: Similarity
messages: Belongs to the HMG-CoA lyase family.

244447:LOC103391967
gene id: 244447:LOC103391967
uniprot id: A0A3P8VG03
names: Subcellular Location Annotation
messages: Membrane
messages: cytoskeleton

244447:engase
gene id: 244447:engase
uniprot id: A0A3P8W9V1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 85 family.
messages: cytosol

244447:ddrgk1
gene id: 244447:ddrgk1
uniprot id: A0A3P8V440
names: Similarity
messages: Belongs to the DDRGK1 family.

244447:LOC103395395
gene id: 244447:LOC103395395
uniprot id: A0A3P8WMH1
names: Domain
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: E3 ubiquitin-protein ligase which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, and transfers it to substrates, generally promoting their degradation by the proteasome.
messages: The N-terminus is composed of the phosphotyrosine binding (PTB) domain, a short linker region and the RING-type zinc finger. The PTB domain, which is also called TKB (tyrosine kinase binding) domain, is composed of three different subdomains: a four-helix bundle (4H), a calcium-binding EF hand and a divergent SH2 domain.

244447:bmp2
gene id: 244447:bmp2
uniprot id: A0A0U1T3U2
names: Similarity
messages: Belongs to the TGF-beta family.

244447:LOC103392428
gene id: 244447:LOC103392428
uniprot id: A0A3P8WM04
names: Subcellular Location Annotation
messages: Secreted

244447:cd79a
gene id: 244447:cd79a
uniprot id: A0A3P8VUZ7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

244447:dnaja2
gene id: 244447:dnaja2
uniprot id: A0A3P8VGM2
names: Subcellular Location Annotation
messages: Membrane

244447:LOC103381920
gene id: 244447:LOC103381920
uniprot id: A0A3P8WI38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

244447:LOC103397759
gene id: 244447:LOC103397759
uniprot id: A0A3P8WWV4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

244447:gfm2
gene id: 244447:gfm2
uniprot id: A0A3P8W4S7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Mitochondrial GTPase that mediates the disassembly of ribosomes from messenger RNA at the termination of mitochondrial protein biosynthesis. Acts in collaboration with MRRF. GTP hydrolysis follows the ribosome disassembly and probably occurs on the ribosome large subunit. Not involved in the GTP-dependent ribosomal translocation step during translation elongation.
messages: Mitochondrion

244447:fgf8
gene id: 244447:fgf8
uniprot id: A0A3P8WIA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heparin-binding growth factors family.
messages: Secreted

244447:LOC103386117
gene id: 244447:LOC103386117
uniprot id: A0A3P8V087
names: Cofactor
names: Similarity
messages: Belongs to the transglutaminase superfamily. Transglutaminase family.
messages: Binds 1 Ca(2+) ion per subunit.

244447:pigc
gene id: 244447:pigc
uniprot id: A0A3P8V0K4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGC family.
messages: Membrane

244447:cers6
gene id: 244447:cers6
uniprot id: A0A3P8VYC6
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Nucleus

244447:LOC103378714
gene id: 244447:LOC103378714
uniprot id: A0A3P8UJN2
names: Subcellular Location Annotation
messages: extracellular space

244447:LOC103378293
gene id: 244447:LOC103378293
uniprot id: A0A3P8W724
names: Similarity
messages: Belongs to the class I fructose-bisphosphate aldolase family.

244447:lrrc8d
gene id: 244447:lrrc8d
uniprot id: A0A3P8WQ51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LRRC8 family.
messages: Cell membrane
messages: Membrane

244447:capn9
gene id: 244447:capn9
uniprot id: A0A3P8VTE4
names: Similarity
messages: Belongs to the peptidase C2 family.

244447:LOC103379944
gene id: 244447:LOC103379944
uniprot id: A0A3P8V6V2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HARBI1 family.
messages: Nucleus

244447:LOC103382905
gene id: 244447:LOC103382905
uniprot id: A0A3P8W086
names: Similarity
messages: Belongs to the CDI family.

244447:serpinh1
gene id: 244447:serpinh1
uniprot id: A0A3P8UUJ9
names: Function
names: Similarity
messages: Belongs to the serpin family.
messages: Binds specifically to collagen. Could be involved as a chaperone in the biosynthetic pathway of collagen.

244447:LOC103396461
gene id: 244447:LOC103396461
uniprot id: A0A3P8WB36
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

244447:c7h6orf58
gene id: 244447:c7h6orf58
uniprot id: A0A3P8WXN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LEG1 family.
messages: Secreted

244447:thrb
gene id: 244447:thrb
uniprot id: A0A068ETB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Nucleus

244447:ciao1
gene id: 244447:ciao1
uniprot id: A0A3P8WJG3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the WD repeat CIA1 family.
messages: Component of the CIA complex.
messages: Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins.

244447:LOC103379554
gene id: 244447:LOC103379554
uniprot id: A0A3P8X2T6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

244447:fbln1
gene id: 244447:fbln1
uniprot id: A0A3P8VUY4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the fibulin family.
messages: Homomultimerizes and interacts with various extracellular matrix components.
messages: Incorporated into fibronectin-containing matrix fibers. May play a role in cell adhesion and migration along protein fibers within the extracellular matrix (ECM). Could be important for certain developmental processes and contribute to the supramolecular organization of ECM architecture, in particular to those of basement membranes.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

244447:adprhl2
gene id: 244447:adprhl2
uniprot id: A0A3P8WEQ5
names: Similarity
messages: Belongs to the ADP-ribosylglycohydrolase family.

244447:pqlc1
gene id: 244447:pqlc1
uniprot id: A0A3P8W3V0
names: Subcellular Location Annotation
messages: Membrane

244447:trappc2l
gene id: 244447:trappc2l
uniprot id: A0A3P8UN46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAPP small subunits family. Sedlin subfamily.
messages: perinuclear region

244447:LOC103393988
gene id: 244447:LOC103393988
uniprot id: A0A3P8VKW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

244447:cdh8
gene id: 244447:cdh8
uniprot id: A0A3P8VEK6
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane
messages: Membrane

244447:p2rx5
gene id: 244447:p2rx5
uniprot id: A0A3P8WCK8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the P2X receptor family.
messages: Functional P2XRs are organized as homomeric and heteromeric trimers.
messages: Membrane
messages: Receptor for ATP that acts as a ligand-gated ion channel.

244447:vasn
gene id: 244447:vasn
uniprot id: A0A3P8WFH7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

244447:LOC103380130
gene id: 244447:LOC103380130
uniprot id: A0A3P8V8J2
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZP domain family. ZPC subfamily.
messages: Cell membrane
messages: Component of the zona pellucida, an extracellular matrix surrounding oocytes which mediates sperm binding, induction of the acrosome reaction and prevents post-fertilization polyspermy. The zona pellucida is composed of 3 to 4 glycoproteins, ZP1, ZP2, ZP3, and ZP4. ZP3 is essential for sperm binding and zona matrix formation.
messages: Proteolytically cleaved before the transmembrane segment to yield the secreted ectodomain incorporated in the zona pellucida.
messages: The ZP domain is involved in the polymerization of the ZP proteins to form the zona pellucida.
messages: Zona pellucida

244447:LOC103376904
gene id: 244447:LOC103376904
uniprot id: A0A3P8VIJ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 7 family.
messages: Golgi apparatus membrane
messages: Membrane
messages: Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids.

244447:LOC103392787
gene id: 244447:LOC103392787
uniprot id: A0A3P8VQH3
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

244447:LOC103384892
gene id: 244447:LOC103384892
uniprot id: A0A3P8V1Y6
names: Subcellular Location Annotation
messages: Nucleus

244447:jph1
gene id: 244447:jph1
uniprot id: A0A3P8VTN9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the junctophilin family.
messages: Cell membrane
messages: Endoplasmic reticulum membrane
messages: Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels.
messages: Membrane

244447:LOC103396278
gene id: 244447:LOC103396278
uniprot id: A0A3P8VM98
names: Subcellular Location Annotation
messages: Membrane

244447:gata4
gene id: 244447:gata4
uniprot id: A0A3P8WZK1
names: Subcellular Location Annotation
messages: Nucleus

244447:LOC103396073
gene id: 244447:LOC103396073
uniprot id: A0A3P8WIR8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC12A transporter family.
messages: Membrane

244447:hgh1
gene id: 244447:hgh1
uniprot id: A0A3P8W2S0
names: Similarity
messages: Belongs to the HGH1 family.

244447:mms19
gene id: 244447:mms19
uniprot id: A0A3P8WWH1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MET18/MMS19 family.
messages: Component of the CIA complex.
messages: Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into apoproteins specifically involved in DNA metabolism and genomic integrity. In the CIA complex, MMS19 acts as an adapter between early-acting CIA components and a subset of cellular target iron-sulfur proteins.
messages: Nucleus
messages: spindle

244447:rnd3
gene id: 244447:rnd3
uniprot id: A0A3P8VEZ0
names: Function
messages: Binds GTP but lacks intrinsic GTPase activity and is resistant to Rho-specific GTPase-activating proteins.

244447:homez
gene id: 244447:homez
uniprot id: A0A3P8WZU4
names: Subcellular Location Annotation
messages: Nucleus

244447:LOC103387354
gene id: 244447:LOC103387354
uniprot id: A0A3P8V826
names: Subcellular Location Annotation
messages: Nucleus

244447:LOC103398437
gene id: 244447:LOC103398437
uniprot id: A0A3P8UFJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CART family.
messages: Secreted

244447:LOC103390675
gene id: 244447:LOC103390675
uniprot id: A0A3P8URJ6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tenascin family. Teneurin subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

244447:pcmtd1
gene id: 244447:pcmtd1
uniprot id: A0A3P8VX97
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

244447:LOC103395408
gene id: 244447:LOC103395408
uniprot id: A0A3P8WN70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

244447:LOC103392851
gene id: 244447:LOC103392851
uniprot id: A0A3P8VVW3
names: Similarity
messages: Belongs to the glycosyltransferase 25 family.

244447:sf3a3
gene id: 244447:sf3a3
uniprot id: A0A3P8VUV4
names: Similarity
messages: Belongs to the SF3A3 family.

244447:rabggta
gene id: 244447:rabggta
uniprot id: A0A3P8URV1
names: Function
names: Similarity
messages: Belongs to the protein prenyltransferase subunit alpha family.
messages: Catalyzes the transfer of a geranyl-geranyl moiety from geranyl-geranyl pyrophosphate to cysteines occuring in specific C-terminal amino acid sequences.
messages: Catalyzes the transfer of a geranylgeranyl moiety from geranylgeranyl diphosphate to both cysteines of Rab proteins with the C-terminal sequence -XXCC, -XCXC and -CCXX, such as RAB1A, RAB3A, RAB5A and RAB7A.

244447:LOC103377973
gene id: 244447:LOC103377973
uniprot id: A0A3P8USH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
messages: clathrin-coated pit
messages: clathrin-coated vesicle
messages: filopodium
messages: microvillus

244447:LOC103393348
gene id: 244447:LOC103393348
uniprot id: A0A3P8V938
names: Subcellular Location Annotation
messages: Nucleus

244447:LOC103387343
gene id: 244447:LOC103387343
uniprot id: A0A3P8UUC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

244447:wipi2
gene id: 244447:wipi2
uniprot id: A0A3P8V8P6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat PROPPIN family.
messages: Preautophagosomal structure membrane

244447:pgf
gene id: 244447:pgf
uniprot id: A0A3P8UDF3
names: Similarity
messages: Belongs to the PDGF/VEGF growth factor family.

244447:entr1
gene id: 244447:entr1
uniprot id: A0A3P8VH99
names: Similarity
messages: Belongs to the ENTR1 family.

244447:LOC103392547
gene id: 244447:LOC103392547
uniprot id: A0A3P8WYS7
names: Similarity
messages: Belongs to the NGF-beta family.

244447:eci1
gene id: 244447:eci1
uniprot id: A0A3P8WKN4
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

244447:LOC103384380
gene id: 244447:LOC103384380
uniprot id: A0A3P8WNU2
names: Similarity
messages: Belongs to the MDFI family.

244447:LOC103394262
gene id: 244447:LOC103394262
uniprot id: A0A3P8WBH4
names: Similarity
messages: Belongs to the peptidase C1 family.

244447:LOC103399846
gene id: 244447:LOC103399846
uniprot id: A0A3P8UJH1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 7 family.
messages: Golgi apparatus membrane
messages: Membrane
messages: Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids.

244447:rfng
gene id: 244447:rfng
uniprot id: A0A3P8VSX5
names: Subcellular Location Annotation
messages: Membrane

244447:srf
gene id: 244447:srf
uniprot id: A0A3P8W7L6
uniprot id: A0A3P8WAP1
names: Subcellular Location Annotation
messages: Nucleus

244447:LOC103379958
gene id: 244447:LOC103379958
uniprot id: A0A3P8V4Q8
names: Similarity
messages: Belongs to the G-alpha family. G(q) subfamily.

244447:LOC103392807
gene id: 244447:LOC103392807
uniprot id: A0A3P8VUJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the otopetrin family.
messages: Cell membrane
messages: Membrane

244447:LOC103382499
gene id: 244447:LOC103382499
uniprot id: A0A3P8UTT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

244447:wnt10b
gene id: 244447:wnt10b
uniprot id: A0A3P8VAK7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

244447:mrrf
gene id: 244447:mrrf
uniprot id: A0A3P8WJ58
names: Function
names: Similarity
messages: Belongs to the RRF family.
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

244447:LOC103382307
gene id: 244447:LOC103382307
uniprot id: A0A3P8UNE1
names: Similarity
messages: Belongs to the globin family.

244447:numb
gene id: 244447:numb
uniprot id: A0A3P8VLN6
uniprot id: A0A3P8VPR8
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Plays a role in the process of neurogenesis.

244447:LOC103381519
gene id: 244447:LOC103381519
uniprot id: A0A3P8VLS1
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily.

244447:rtcb
gene id: 244447:rtcb
uniprot id: A0A3P8USK7
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.
messages: Catalytic component of the tRNA-splicing ligase complex.
messages: Catalytic subunit of the tRNA-splicing ligase complex that acts by directly joining spliced tRNA halves to mature-sized tRNAs by incorporating the precursor-derived splice junction phosphate into the mature tRNA as a canonical 3',5'-phosphodiester. May act as an RNA ligase with broad substrate specificity, and may function toward other RNAs.
messages: Cytoplasm
messages: Ligation probably proceeds through 3 nucleotidyl transfer steps, with 2',3'-cyclic phosphate termini being hydrolyzed to 3'-P termini in a step that precedes 3'-P activation with GMP. In the first nucleotidyl transfer step, RTCB reacts with GTP to form a covalent RTCB-histidine-GMP intermediate with release of PPi; in the second step, the GMP moiety is transferred to the RNA 3'-P; in the third step, the 5'-OH from the opposite RNA strand attacks the activated 3'-P to form a 3',5'-phosphodiester bond and release GMP.

244447:alox5
gene id: 244447:alox5
uniprot id: A0A3P8V857
names: Caution
names: Similarity
messages: Belongs to the lipoxygenase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

244447:LOC103397254
gene id: 244447:LOC103397254
uniprot id: A0A3P8WFZ0
names: Similarity
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family.

244447:tcta
gene id: 244447:tcta
uniprot id: A0A3P8X4K6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCTA family.
messages: Membrane

244447:LOC103388214
gene id: 244447:LOC103388214
uniprot id: A0A3P8UJI1
names: Similarity
messages: Belongs to the S-100 family.

244447:lclat1
gene id: 244447:lclat1
uniprot id: A0A3P8UP05
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

244447:LOC103397791
gene id: 244447:LOC103397791
uniprot id: A0A3P8X0F1
names: Similarity
messages: Belongs to the FAH family.

244447:adamts1
gene id: 244447:adamts1
uniprot id: A0A3P8VZ62
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

244447:tmem86a
gene id: 244447:tmem86a
uniprot id: A0A3P8VJR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM86 family.
messages: Membrane

244447:LOC103394114
gene id: 244447:LOC103394114
uniprot id: A0A3P8WH68
names: Subcellular Location Annotation
messages: Membrane

244447:odc1
gene id: 244447:odc1
uniprot id: A0A3P8WJV8
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

244447:slc39a8
gene id: 244447:slc39a8
uniprot id: A0A3P8VW90
names: Subcellular Location Annotation
messages: Membrane

244447:mettl14
gene id: 244447:mettl14
uniprot id: A0A3P8VPA5
names: Similarity
messages: Belongs to the MT-A70-like family.

244447:srm
gene id: 244447:srm
uniprot id: A0A3P8UYW7
names: Similarity
messages: Belongs to the spermidine/spermine synthase family.

244447:arhgap32
gene id: 244447:arhgap32
uniprot id: A0A3P8WJD0
uniprot id: A0A3P8WMC9
uniprot id: A0A3P8WQ84
names: Similarity
messages: Belongs to the PX domain-containing GAP family.

244447:LOC103390990
gene id: 244447:LOC103390990
uniprot id: A0A3P8VUI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

244447:aebp1
gene id: 244447:aebp1
uniprot id: A0A3P8VI48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M14 family.
messages: Secreted

244447:nudt1
gene id: 244447:nudt1
uniprot id: A0A3P8X2A5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Nudix hydrolase family.
messages: Monomer.
messages: Nucleus

244447:yipf1
gene id: 244447:yipf1
uniprot id: A0A3P8WCJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YIP1 family.
messages: Endosome membrane
messages: Late endosome membrane
messages: Membrane
messages: cis-Golgi network membrane
messages: trans-Golgi network membrane

244447:LOC103388692
gene id: 244447:LOC103388692
uniprot id: A0A3P8VIE2
names: Similarity
messages: Belongs to the S-100 family.

244447:atp5po
gene id: 244447:atp5po
uniprot id: A0A3P8WEZ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain and the peripheric stalk, which acts as a stator to hold the catalytic alpha(3)beta(3) subcomplex and subunit a/ATP6 static relative to the rotary elements.
messages: Mitochondrion inner membrane

244447:clstn2
gene id: 244447:clstn2
uniprot id: A0A3P8W3R2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Golgi apparatus membrane
messages: Membrane

244447:LOC103388518
gene id: 244447:LOC103388518
uniprot id: A0A3P8V185
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the shootin family.
messages: axon
messages: cytoskeleton
messages: filopodium
messages: lamellipodium

244447:LOC103382576
gene id: 244447:LOC103382576
uniprot id: A0A1L6KTK5
names: Function
messages: Plays a role in skin pigmentation by antagonizing the action of melanotropin alpha. Induces melanin concentration within the melanophores. May participate in the control of the hypothalamo-pituitary adrenal gland axis by inhibiting the release of ACTH.

244447:rps6ka6
gene id: 244447:rps6ka6
uniprot id: A0A3P8WNR3
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.

244447:LOC103389443
gene id: 244447:LOC103389443
uniprot id: A0A3P8UWS4
names: Subcellular Location Annotation
messages: Cell membrane
messages: invadopodium membrane
messages: lamellipodium membrane

244447:LOC103382975
gene id: 244447:LOC103382975
uniprot id: A0A3P8WE60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protease inhibitor I35 (TIMP) family.
messages: extracellular matrix

244447:sdk2
gene id: 244447:sdk2
uniprot id: A0A3P8W2T7
uniprot id: A0A3P8W7Q1
uniprot id: A0A3P8WAK5
names: Subcellular Location Annotation
messages: Membrane

244447:LOC103392520
gene id: 244447:LOC103392520
uniprot id: A0A3P8WX94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the krueppel C2H2-type zinc-finger protein family.
messages: Nucleus

244447:itm2b
gene id: 244447:itm2b
uniprot id: A0A3P8WY49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ITM2 family.
messages: Membrane

244447:ncstn
gene id: 244447:ncstn
uniprot id: A0A3P8X5C9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nicastrin family.
messages: Membrane

244447:LOC103387070
gene id: 244447:LOC103387070
uniprot id: A0A3P8UXB2
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3 GTPase family.

244447:LOC103387334
gene id: 244447:LOC103387334
uniprot id: A0A3P8V7T2
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Putative Notch ligand involved in the mediation of Notch signaling.

244447:bves
gene id: 244447:bves
uniprot id: A0A3P8W6S1
names: Similarity
messages: Belongs to the popeye family.

244447:inka1
gene id: 244447:inka1
uniprot id: A0A3P8UG30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the INKA family.
messages: Nucleus

244447:ppat
gene id: 244447:ppat
uniprot id: A0A3P8UYC9
names: Cofactor
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

244447:hscb
gene id: 244447:hscb
uniprot id: A0A3P8V5Z0
names: Similarity
messages: Belongs to the HscB family.

244447:LOC103385705
gene id: 244447:LOC103385705
uniprot id: A0A3P8X2M8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

244447:taf4
gene id: 244447:taf4
uniprot id: A0A3P8V4L7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF4 family.
messages: Nucleus

244447:LOC103391394
gene id: 244447:LOC103391394
uniprot id: A0A3P8WXH3
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: May be involved in podosome and invadosome formation.
messages: invadopodium
messages: podosome

244447:hdac9
gene id: 244447:hdac9
uniprot id: A0A3P8UZ47
uniprot id: A0A3P8UZ51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone deacetylase family. HD type 2 subfamily.
messages: Nucleus

244447:LOC103377376
gene id: 244447:LOC103377376
uniprot id: A0A3P8WV08
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane
messages: Membrane

244447:KEH01 p08
gene id: 244447:KEH01_p08
uniprot id: C5H0F8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase A chain family.
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Membrane
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Key component of the proton channel; it may play a direct role in the translocation of protons across the membrane.
messages: Mitochondrion inner membrane

244447:bsx
gene id: 244447:bsx
uniprot id: A0A3P8WV15
names: Subcellular Location Annotation
messages: Nucleus

244447:LOC103383836
gene id: 244447:LOC103383836
uniprot id: A0A3P8VNF1
names: Similarity
messages: Belongs to the SPARC family.

244447:LOC103388199
gene id: 244447:LOC103388199
uniprot id: A0A3P8UIQ7
uniprot id: A0A3P8US95
names: Function
names: Subcellular Location Annotation
messages: General regulator of phagocytosis. Required to uptake Gram negative bacterium by macrophages.
messages: Golgi apparatus
messages: Membrane
messages: Mitochondrion

244447:capzb
gene id: 244447:capzb
uniprot id: A0A3P8URA6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the F-actin-capping protein beta subunit family.
messages: F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.
messages: Heterodimer of an alpha and a beta subunit.
messages: cytoskeleton

244447:LOC103385562
gene id: 244447:LOC103385562
uniprot id: A0A3P8X6Q0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPATS2 family.
messages: Cytoplasm

244447:LOC103387006
gene id: 244447:LOC103387006
uniprot id: A0A3P8UNY5
names: Similarity
messages: Belongs to the cytochrome P450 family.

244447:chst14
gene id: 244447:chst14
uniprot id: A0A3P8UZS3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 2 family.
messages: Golgi apparatus membrane
messages: Membrane

244447:LOC103389087
gene id: 244447:LOC103389087
uniprot id: A0A3P8WLA4
names: Similarity
messages: Belongs to the GADD45 family.

244447:mthfd1
gene id: 244447:mthfd1
uniprot id: A0A3P8UIX3
names: Similarity
names: Subunit
messages: Homodimer.
messages: In the C-terminal section; belongs to the formate--tetrahydrofolate ligase family.
messages: In the N-terminal section; belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.

244447:LOC103390066
gene id: 244447:LOC103390066
uniprot id: A0A3P8W6W7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TNF receptor-associated factor family.
messages: Cytoplasm

244447:slc18a2
gene id: 244447:slc18a2
uniprot id: A0A3P8WM34
names: Subcellular Location Annotation
messages: Membrane

244447:furin
gene id: 244447:furin
uniprot id: A0A3P8W7L7
names: Similarity
messages: Belongs to the peptidase S8 family.

244447:hsd3b1
gene id: 244447:hsd3b1
uniprot id: A0A3P8VJ35
names: Similarity
messages: Belongs to the 3-beta-HSD family.

244447:gpd2
gene id: 244447:gpd2
uniprot id: A0A3P8V507
uniprot id: A0A3P8V8T4
names: Function
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Calcium-responsive mitochondrial glycerol-3-phosphate dehydrogenase which seems to be a key component of the pancreatic beta-cell glucose-sensing device.

244447:LOC103379946
gene id: 244447:LOC103379946
uniprot id: A0A3P8UT33
names: Subcellular Location Annotation
names: Subunit
messages: Efficient DNA binding requires dimerization with another bHLH protein.
messages: Nucleus

244447:LOC103396194
gene id: 244447:LOC103396194
uniprot id: A0A3P8WVI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Membrane

244447:sntb1
gene id: 244447:sntb1
uniprot id: A0A3P8V1N1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the syntrophin family.
messages: Cell junction
messages: cytoskeleton

244447:LOC103388732
gene id: 244447:LOC103388732
uniprot id: A0A3P8VPN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CALHM family.
messages: Membrane

244447:cdca7l
gene id: 244447:cdca7l
uniprot id: A0A3P8VHQ4
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

244447:syngr3
gene id: 244447:syngr3
uniprot id: A0A3P8WVT0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptogyrin family.
messages: Membrane

244447:LOC103392018
gene id: 244447:LOC103392018
uniprot id: A0A3P8VIH5
names: Subcellular Location Annotation
messages: Membrane

244447:rhag
gene id: 244447:rhag
uniprot id: A0A3P8WYP4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonium transporter (TC 2.A.49) family. Rh subfamily.
messages: Cell membrane
messages: Functions as an ammonia transporter. May play a role in the elimination of ammonia in the gill.
messages: Membrane

244447:LOC103393035
gene id: 244447:LOC103393035
uniprot id: A0A3P8W3W7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

244447:oaf
gene id: 244447:oaf
uniprot id: A0A3P8WH35
names: Similarity
messages: Belongs to the OAF family.

244447:fnip1
gene id: 244447:fnip1
uniprot id: A0A3P8VWJ2
uniprot id: A0A3P8VZG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FNIP family.
messages: Lysosome membrane
messages: Membrane

244447:LOC103391689
gene id: 244447:LOC103391689
uniprot id: A0A3P8UTG2
names: Subcellular Location Annotation
messages: Membrane

244447:hnrnpc
gene id: 244447:hnrnpc
uniprot id: A0A3P8X358
names: Similarity
messages: Belongs to the RRM HNRPC family. RALY subfamily.

244447:gins4
gene id: 244447:gins4
uniprot id: A0A3P8VED2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GINS4/SLD5 family.
messages: Chromosome
messages: Nucleus
messages: Required for initiation of chromosomal DNA replication. Core component of CDC45-MCM-GINS (CMG) helicase, the molecular machine that unwinds template DNA during replication, and around which the replisome is built.

244447:tmem14a
gene id: 244447:tmem14a
uniprot id: A0A3P8VGL2
names: Similarity
messages: Belongs to the TMEM14 family.

244447:pou4f3
gene id: 244447:pou4f3
uniprot id: A0A3P8W736
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POU transcription factor family.
messages: Nucleus

244447:LOC103392995
gene id: 244447:LOC103392995
uniprot id: A0A3P8WBN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCRIP family.
messages: Nucleus
messages: Stress granule

244447:LOC103397585
gene id: 244447:LOC103397585
uniprot id: A0A3P8WFV0
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

244447:impad1
gene id: 244447:impad1
uniprot id: A0A3P8WMS1
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

244447:LOC103387463
gene id: 244447:LOC103387463
uniprot id: A0A3P8VDP5
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

244447:LOC103381952
gene id: 244447:LOC103381952
uniprot id: A0A3P8WIU0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

244447:ngb
gene id: 244447:ngb
uniprot id: A0A3P8UDI1
names: Similarity
messages: Belongs to the globin family.

244447:etfdh
gene id: 244447:etfdh
uniprot id: A0A3P8UW51
names: Cofactor
names: Function
messages: Accepts electrons from ETF and reduces ubiquinone.
messages: Binds 1 [4Fe-4S] cluster.

244447:LOC107988356
gene id: 244447:LOC107988356
uniprot id: A0A1V0QH40
names: Similarity
messages: Belongs to the nanos family.

244447:LOC103394751
gene id: 244447:LOC103394751
uniprot id: A0A3P8VQ79
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

244447:LOC103380488
gene id: 244447:LOC103380488
uniprot id: A2TF39
names: Similarity
messages: Belongs to the cytochrome P450 family.

244447:acsl5
gene id: 244447:acsl5
uniprot id: A0A3P8VUK3
names: Function
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of long-chain fatty acids to their active form acyl-CoAs for both synthesis of cellular lipids, and degradation via beta-oxidation.

244447:LOC103390298
gene id: 244447:LOC103390298
uniprot id: A0A3P8WX61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

244447:metap1d
gene id: 244447:metap1d
uniprot id: A0A3P8W8B3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).

244447:clcn4
gene id: 244447:clcn4
uniprot id: A0A3P8VHM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel (TC 2.A.49) family.
messages: Membrane

244447:yars
gene id: 244447:yars
uniprot id: A0A3P8VRA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Nucleus

244447:LOC103377781
gene id: 244447:LOC103377781
uniprot id: A0A3P8V6A4
names: Subcellular Location Annotation
messages: Nucleus

244447:LOC103394940
gene id: 244447:LOC103394940
uniprot id: A0A3P8WFS2
uniprot id: A0A3P8WHV0
names: Subcellular Location Annotation
messages: Chromosome
messages: Nucleus

244447:LOC103397322
gene id: 244447:LOC103397322
uniprot id: A0A3P8VH88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

244447:LOC103393045
gene id: 244447:LOC103393045
uniprot id: A0A3P8WCJ9
names: Similarity
messages: Belongs to the 3-beta-HSD family.

244447:enkur
gene id: 244447:enkur
uniprot id: A0A3P8WQ15
names: Subcellular Location Annotation
messages: cilium axoneme

244447:gjd2
gene id: 244447:gjd2
uniprot id: A0A3P8UPB3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

244447:spen
gene id: 244447:spen
uniprot id: A0A3P8UUL1
names: Similarity
messages: Belongs to the RRM Spen family.

244447:LOC103385013
gene id: 244447:LOC103385013
uniprot id: A0A3P8VAU6
names: Similarity
messages: Belongs to the OSBP family.

244447:ap1m2
gene id: 244447:ap1m2
uniprot id: A0A3P8W4R4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adaptor complexes medium subunit family.
messages: Golgi apparatus
messages: Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules.
messages: clathrin-coated vesicle membrane

244447:csgalnact1
gene id: 244447:csgalnact1
uniprot id: A0A3P8ULH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chondroitin N-acetylgalactosaminyltransferase family.
messages: Golgi stack membrane
messages: Membrane

244447:trpc1
gene id: 244447:trpc1
uniprot id: A0A3P8WB30
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transient receptor (TC 1.A.4) family. STrpC subfamily. TRPC1 sub-subfamily.
messages: Membrane
messages: Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Seems to be also activated by intracellular calcium store depletion.

244447:LOC103397959
gene id: 244447:LOC103397959
uniprot id: A0A3P8VF25
names: Similarity
messages: Belongs to the FHIP family.

244447:mms22l
gene id: 244447:mms22l
uniprot id: A0A3P8W672
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MMS22 family. MMS22L subfamily.
messages: Chromosome
messages: Nucleus

244447:LOC103378403
gene id: 244447:LOC103378403
uniprot id: A0A3P8WFJ9
names: Similarity
messages: Belongs to the arrestin family.

244447:LOC103380722
gene id: 244447:LOC103380722
uniprot id: A0A3P8WY71
names: Function
messages: Regulates (in vitro) the inhibition of rhodopsin phosphorylation in a calcium-dependent manner.

244447:LOC103389977
gene id: 244447:LOC103389977
uniprot id: A0A3P8VW43
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

244447:pknox1
gene id: 244447:pknox1
uniprot id: A0A3P8WZN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/MEIS homeobox family.
messages: Nucleus

244447:LOC103392320
gene id: 244447:LOC103392320
uniprot id: A0A3P8W7I8
names: Subcellular Location Annotation
messages: extracellular space

244447:LOC103389308
gene id: 244447:LOC103389308
uniprot id: A0A3P8UHC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

244447:LOC103394973
gene id: 244447:LOC103394973
uniprot id: A0A3P8WJ42
names: Subcellular Location Annotation
messages: Membrane

244447:kirrel1
gene id: 244447:kirrel1
uniprot id: A0A3P8W2A3
names: Subcellular Location Annotation
messages: Membrane

244447:LOC103381549
gene id: 244447:LOC103381549
uniprot id: A0A3P8VS38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Cell membrane
messages: Cytoplasmic vesicle
messages: Endosome
messages: Membrane
messages: Perikaryon
messages: Recycling endosome
messages: Synaptic cell membrane
messages: Vesicle
messages: dendrite

244447:LOC103392345
gene id: 244447:LOC103392345
uniprot id: A0A3P8WBA2
names: Similarity
messages: Belongs to the actin family. ARP3 subfamily.

244447:LOC103376722
gene id: 244447:LOC103376722
uniprot id: A0A3P8VE67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FMO family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Microsome membrane

244447:sema3a
gene id: 244447:sema3a
uniprot id: A0A3P8VKM0
names: Caution
names: Similarity
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

244447:fsip1
gene id: 244447:fsip1
uniprot id: A0A3P8UAF5
names: Similarity
messages: Belongs to the FSIP1 family.

244447:dhodh
gene id: 244447:dhodh
uniprot id: A0A3P8UP44
names: Function
names: Similarity
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor. Required for UMP biosynthesis via de novo pathway.

244447:kremen1
gene id: 244447:kremen1
uniprot id: A0A3P8X5G6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

244447:LOC103391462
gene id: 244447:LOC103391462
uniprot id: A0A3P8WY52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CENP-U/AME1 family.
messages: Nucleus

244447:tgfb1i1
gene id: 244447:tgfb1i1
uniprot id: A0A3P8VJV6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paxillin family.
messages: Functions as a molecular adapter coordinating multiple protein-protein interactions at the focal adhesion complex and in the nucleus. Links various intracellular signaling modules to plasma membrane receptors and regulates the Wnt and TGFB signaling pathways.
messages: Nucleus matrix
messages: The LD (leucine and aspartate-rich) motif 3 mediates interaction with GIT1 and functions as a nuclear export signal.
messages: cytoskeleton
messages: focal adhesion

244447:ubald1
gene id: 244447:ubald1
uniprot id: A0A3P8X230
names: Similarity
messages: Belongs to the UBALD family.

244447:LOC103395476
gene id: 244447:LOC103395476
uniprot id: A0A3P8WYN4
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.

244447:cyyr1
gene id: 244447:cyyr1
uniprot id: A0A3P8W4P8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CYYR1 family.
messages: Membrane

244447:LOC103379338
gene id: 244447:LOC103379338
uniprot id: A0A3P8UX83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCM family.
messages: Nucleus

244447:LOC103393708
gene id: 244447:LOC103393708
uniprot id: A0A0N9H565
uniprot id: A0A0N9H7N8
names: Similarity
messages: Belongs to the DEAD box helicase family.

244447:sugp1
gene id: 244447:sugp1
uniprot id: A0A3P8WAI1
names: Subcellular Location Annotation
messages: Nucleus

244447:LOC103394776
gene id: 244447:LOC103394776
uniprot id: A0A3P8VVU3
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

244447:LOC103383428
gene id: 244447:LOC103383428
uniprot id: A0A3P8UJB6
names: Subcellular Location Annotation
messages: Nucleus

244447:LOC103382363
gene id: 244447:LOC103382363
uniprot id: A0A3P8UC02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fascin family.
messages: cytoskeleton

244447:LOC103391375
gene id: 244447:LOC103391375
uniprot id: A0A3P8WQW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CYSTM1 family.
messages: Membrane

244447:agtr1
gene id: 244447:agtr1
uniprot id: A0A3P8WL59
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for angiotensin II, a vasoconstricting peptide, which acts as a key regulator of blood pressure and sodium retention by the kidney. The activated receptor in turn couples to G-alpha proteins G(q) and thus activates phospholipase C and increases the cytosolic Ca(2+) concentrations, which in turn triggers cellular responses such as stimulation of protein kinase C.

244447:LOC103397992
gene id: 244447:LOC103397992
uniprot id: A0A3P8VJ50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC12A transporter family.
messages: Cell membrane
messages: Membrane

244447:LOC103381943
gene id: 244447:LOC103381943
uniprot id: A0A3P8WJ95
names: Similarity
messages: Belongs to the PPase family.

244447:LOC103388319
gene id: 244447:LOC103388319
uniprot id: A0A3P8V0J4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Binds 2 magnesium ions per subunit. Is also active with manganese (in vitro).
messages: Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.
messages: Membrane

244447:tamm41
gene id: 244447:tamm41
uniprot id: A0A3P8X222
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAM41 family.
messages: Catalyzes the conversion of phosphatidic acid (PA) to CDP-diacylglycerol (CDP-DAG), an essential intermediate in the synthesis of phosphatidylglycerol, cardiolipin and phosphatidylinositol.
messages: Mitochondrion inner membrane

244447:tspan6
gene id: 244447:tspan6
uniprot id: A0A3P8UNX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

244447:rbks
gene id: 244447:rbks
uniprot id: A0A3P8UVS4
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

244447:cachd1
gene id: 244447:cachd1
uniprot id: A0A3P8WND3
names: Similarity
messages: Belongs to the calcium channel subunit alpha-2/delta family.

244447:tpm1
gene id: 244447:tpm1
uniprot id: A0A3P8UPB8
uniprot id: A0A3P8UPC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tropomyosin family.
messages: cytoskeleton

244447:pcnx1
gene id: 244447:pcnx1
uniprot id: A0A3P8VJB4
uniprot id: A0A3P8VJF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pecanex family.
messages: Membrane

244447:pdgfc
gene id: 244447:pdgfc
uniprot id: A0A3P8UYU6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PDGF/VEGF growth factor family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

244447:LOC103394928
gene id: 244447:LOC103394928
uniprot id: A0A3P8WGL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase VIIb family.
messages: Membrane
messages: Mitochondrion inner membrane

244447:ak5
gene id: 244447:ak5
uniprot id: A0A3P8X143
uniprot id: A0A3P8X6J2
names: Similarity
messages: Belongs to the adenylate kinase family.

244447:ambp
gene id: 244447:ambp
uniprot id: A0A3P8ULJ3
names: Similarity
names: Subcellular Location Annotation
messages: In the N-terminal section; belongs to the calycin superfamily. Lipocalin family.
messages: Secreted

244447:LOC103391169
gene id: 244447:LOC103391169
uniprot id: A0A3P8W8L4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family.
messages: Catalyzes the synthesis of phosphoribosylpyrophosphate (PRPP) that is essential for nucleotide synthesis.
messages: Homodimer. The active form is probably a hexamer composed of 3 homodimers.

244447:pigx
gene id: 244447:pigx
uniprot id: A0A3P8UZY4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGX family.
messages: Endoplasmic reticulum membrane
messages: Essential component of glycosylphosphatidylinositol-mannosyltransferase 1 which transfers the first of the 4 mannoses in the GPI-anchor precursors during GPI-anchor biosynthesis.

244447:fxr1
gene id: 244447:fxr1
uniprot id: A0A3P8UQ67
names: Similarity
messages: Belongs to the FMR1 family.

244447:ebp
gene id: 244447:ebp
uniprot id: A0A3P8UL12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EBP family.
messages: Endoplasmic reticulum membrane
messages: Membrane

244447:LOC103381480
gene id: 244447:LOC103381480
uniprot id: A0A3P8VRC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M14 family.
messages: Secreted

244447:LOC103386274
gene id: 244447:LOC103386274
uniprot id: A0A3P8VDZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA1 family.
messages: Membrane

244447:prph
gene id: 244447:prph
uniprot id: A0A3P8UTK4
names: Similarity
messages: Belongs to the intermediate filament family.

244447:KEH01 p12
gene id: 244447:KEH01_p12
uniprot id: C5H0F4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 2 family.
messages: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I.
messages: Membrane
messages: Mitochondrion inner membrane

244447:gpr37
gene id: 244447:gpr37
uniprot id: A0A3P8VTU4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

244447:clrn3
gene id: 244447:clrn3
uniprot id: A0A3P8VMP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the clarin family.
messages: Membrane

244447:LOC103390944
gene id: 244447:LOC103390944
uniprot id: A0A3P8V6G4
names: Similarity
messages: Belongs to the syntaxin family.

244447:LOC103389506
gene id: 244447:LOC103389506
uniprot id: A0A3P8V8T2
names: Similarity
messages: Belongs to the TSC-22/Dip/Bun family.

244447:cntnap5
gene id: 244447:cntnap5
uniprot id: A0A3P8V200
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neurexin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

244447:tmem177
gene id: 244447:tmem177
uniprot id: A0A3P8WQ83
names: Function
names: Similarity
messages: Belongs to the TMEM177 family.
messages: Plays a role in the early steps of cytochrome c oxidase subunit II (MT-CO2/COX2) maturation and is required for the stabilization of COX20 and the newly synthesized MT-CO2/COX2 protein.

244447:hoxc11
gene id: 244447:hoxc11
uniprot id: A0A3P8VAN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus

244447:LOC103391637
gene id: 244447:LOC103391637
uniprot id: A0A3P8UVS3
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

244447:siah1
gene id: 244447:siah1
uniprot id: A0A3P8X5X9
names: Domain
names: Function
names: Similarity
messages: Belongs to the SINA (Seven in absentia) family.
messages: E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.
messages: The RING-type zinc finger domain is essential for ubiquitin ligase activity.
messages: The SBD domain (substrate-binding domain) mediates the interaction with substrate proteins. It is related to the TRAF family.

244447:shpk
gene id: 244447:shpk
uniprot id: A0A3P8WFN0
names: Similarity
messages: Belongs to the FGGY kinase family.

244447:LOC103391542
gene id: 244447:LOC103391542
uniprot id: A0A3P8X061
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

244447:LOC103381080
gene id: 244447:LOC103381080
uniprot id: A0A3P8UU23
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In association with mitochondrial contact site and cristae organizing system (MICOS) complex components and mitochondrial outer membrane sorting assembly machinery (SAM) complex components may regulate mitochondrial dynamics playing a role in determining mitochondrial length, distribution and motility.
messages: Membrane
messages: Mitochondrion outer membrane

244447:LOC103399726
gene id: 244447:LOC103399726
uniprot id: A0A3P8UPG8
names: Similarity
messages: Belongs to the AccD/PCCB family.

244447:LOC103395443
gene id: 244447:LOC103395443
uniprot id: A0A3P8WRJ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

244447:tctn3
gene id: 244447:tctn3
uniprot id: A0A3P8VGF9
names: Similarity
names: Subunit
messages: Belongs to the tectonic family.
messages: Part of the tectonic-like complex (also named B9 complex).

244447:LOC103386524
gene id: 244447:LOC103386524
uniprot id: A0A3P8WAS4
names: Similarity
names: Subunit
messages: Belongs to the 14-3-3 family.
messages: Homodimer, and heterodimer with other family members.

244447:ston1
gene id: 244447:ston1
uniprot id: A0A3P8VWE1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Stoned B family.
messages: Cytoplasm
messages: May be involved in the endocytic machinery.

244447:LOC103392321
gene id: 244447:LOC103392321
uniprot id: A0A3P8WCX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UDP-glycosyltransferase family.
messages: Membrane

244447:foxk2
gene id: 244447:foxk2
uniprot id: A0A3P8UVM3
names: Subcellular Location Annotation
messages: Nucleus

244447:sumf1
gene id: 244447:sumf1
uniprot id: A0A3P8UTI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfatase-modifying factor family.
messages: Endoplasmic reticulum lumen

244447:LOC103377210
gene id: 244447:LOC103377210
uniprot id: A0A3P8WN11
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the DNA photolyase class-1 family.
messages: Binds 1 5,10-methenyltetrahydrofolate (MTHF) per subunit.
messages: Binds 1 FAD per subunit.
messages: May have a photoreceptor function.

244447:LOC103397722
gene id: 244447:LOC103397722
uniprot id: A0A3P8WG13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

244447:fgf14
gene id: 244447:fgf14
uniprot id: A0A3P8UZY8
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

244447:rmi1
gene id: 244447:rmi1
uniprot id: A0A3P8VYV9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RMI1 family.
messages: Essential component of the RMI complex, a complex that plays an important role in the processing of homologous recombination intermediates to limit DNA crossover formation in cells. Promotes TOP3A binding to double Holliday junctions (DHJ) and hence stimulates TOP3A-mediated dissolution. Required for BLM phosphorylation during mitosis. Within the BLM complex, required for BLM and TOP3A stability.
messages: Nucleus

244447:atp6v1h
gene id: 244447:atp6v1h
uniprot id: A0A3P8VZU2
uniprot id: A0A3P8W2C6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the V-ATPase H subunit family.
messages: Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.

244447:LOC103393287
gene id: 244447:LOC103393287
uniprot id: A0A3P8VBC1
names: Similarity
messages: Belongs to the peptidase A1 family.

244447:LOC103379367
gene id: 244447:LOC103379367
uniprot id: A0A3P8VSU8
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

244447:LOC103397695
gene id: 244447:LOC103397695
uniprot id: A0A3P8WPJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

244447:ndufb6
gene id: 244447:ndufb6
uniprot id: A0A3P8URQ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFB6 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

244447:dnajb12
gene id: 244447:dnajb12
uniprot id: A0A3P8WPQ2
names: Subcellular Location Annotation
messages: Membrane

244447:adamts5
gene id: 244447:adamts5
uniprot id: A0A3P8W0C1
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

244447:atp5mc1
gene id: 244447:atp5mc1
uniprot id: A0A3P8VZM9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Membrane
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. A homomeric c-ring of probably 10 subunits is part of the complex rotary element.
messages: Mitochondrion membrane

244447:irf7
gene id: 244447:irf7
uniprot id: H2ESV0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IRF family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

244447:arid1a
gene id: 244447:arid1a
uniprot id: A0A3P8V107
names: Subcellular Location Annotation
messages: Nucleus

244447:paf1
gene id: 244447:paf1
uniprot id: A0A3P8W161
names: Similarity
messages: Belongs to the PAF1 family.

244447:tpd52
gene id: 244447:tpd52
uniprot id: A0A3P8WJ64
names: Similarity
messages: Belongs to the TPD52 family.

244447:btf3l4
gene id: 244447:btf3l4
uniprot id: A0A3P8X6J8
names: Similarity
messages: Belongs to the NAC-beta family.

244447:LOC103379123
gene id: 244447:LOC103379123
uniprot id: A0A3P8W5J3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

244447:sfxn2
gene id: 244447:sfxn2
uniprot id: A0A3P8W8G1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sideroflexin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Mitochondrion membrane

244447:aprt
gene id: 244447:aprt
uniprot id: A0A3P8WTW5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm

244447:ctnnbip1
gene id: 244447:ctnnbip1
uniprot id: A0A3P8VBS6
names: Similarity
messages: Belongs to the CTNNBIP1 family.