2325:TKV RS06250
gene id: 2325:TKV_RS06250
uniprot id: A0A097ARN2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

2325:TKV RS08015
gene id: 2325:TKV_RS08015
uniprot id: A0A097ASL2
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

2325:TKV RS10195
gene id: 2325:TKV_RS10195
uniprot id: A0A097ATT0
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

2325:TKV RS07485
gene id: 2325:TKV_RS07485
uniprot id: A0A097ASD6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell membrane
messages: Self-interacts. Interacts with FtsZ.

2325:TKV RS03150
gene id: 2325:TKV_RS03150
uniprot id: A0A097APT9
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2325:TKV RS06620
gene id: 2325:TKV_RS06620
uniprot id: A0A097ARV5
names: Similarity
messages: Belongs to the DprA/Smf family.

2325:TKV RS04100
gene id: 2325:TKV_RS04100
uniprot id: A0A097AQF9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

2325:TKV RS03900
gene id: 2325:TKV_RS03900
uniprot id: A0A097AQA3
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

2325:TKV RS05505
gene id: 2325:TKV_RS05505
uniprot id: A0A097AR85
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

2325:TKV RS05480
gene id: 2325:TKV_RS05480
uniprot id: A0A097AR80
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

2325:TKV RS05535
gene id: 2325:TKV_RS05535
uniprot id: A0A097AR79
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

2325:TKV RS00665
gene id: 2325:TKV_RS00665
uniprot id: A0A097ANE6
names: Function
names: Similarity
messages: Belongs to the HypA/HybF family.
messages: Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.

2325:TKV RS11320
gene id: 2325:TKV_RS11320
uniprot id: A0A097AUH1
names: Similarity
messages: Belongs to the glycosyl hydrolase 26 family.

2325:TKV RS00480
gene id: 2325:TKV_RS00480
uniprot id: A0A097ANA5
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

2325:TKV RS04900
gene id: 2325:TKV_RS04900
uniprot id: A0A097AQV3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

2325:TKV RS08980
gene id: 2325:TKV_RS08980
uniprot id: A0A097AT69
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
messages: This function is generally fulfilled by the C-terminal part of HisG, which is missing in some bacteria such as this one.

2325:TKV RS07470
gene id: 2325:TKV_RS07470
uniprot id: A0A097ASA9
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

2325:TKV RS06165
gene id: 2325:TKV_RS06165
uniprot id: A0A097ARK3
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

2325:TKV RS03110
gene id: 2325:TKV_RS03110
uniprot id: A0A097APW1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

2325:TKV RS00800
gene id: 2325:TKV_RS00800
uniprot id: A0A097ANH0
names: Subcellular Location Annotation
messages: Membrane

2325:TKV RS11270
gene id: 2325:TKV_RS11270
uniprot id: A0A097AUF9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

2325:TKV RS01425
gene id: 2325:TKV_RS01425
uniprot id: A0A097ANW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

2325:TKV RS07945
gene id: 2325:TKV_RS07945
uniprot id: A0A097ASI2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

2325:TKV RS07065
gene id: 2325:TKV_RS07065
uniprot id: A0A097AS42
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

2325:TKV RS00555
gene id: 2325:TKV_RS00555
uniprot id: A0A097ANC0
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

2325:TKV RS09255
gene id: 2325:TKV_RS09255
uniprot id: A0A097ATB2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic Ku family.
messages: Homodimer. Interacts with LigD.
messages: With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD.

2325:TKV RS03480
gene id: 2325:TKV_RS03480
uniprot id: A0A097AQ11
names: Similarity
messages: Belongs to the phosphohexose mutase family.

2325:TKV RS02540
gene id: 2325:TKV_RS02540
uniprot id: A0A097APH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

2325:TKV RS11215
gene id: 2325:TKV_RS11215
uniprot id: A0A097AUC3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PrsA family.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins.

2325:TKV RS12015
gene id: 2325:TKV_RS12015
uniprot id: A0A097AUQ6
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

2325:TKV RS01605
gene id: 2325:TKV_RS01605
uniprot id: A0A097ANZ7
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

2325:TKV RS01990
gene id: 2325:TKV_RS01990
uniprot id: A0A097AP90
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

2325:TKV RS03995
gene id: 2325:TKV_RS03995
uniprot id: A0A097AQB5
names: Cofactor
messages: Binds 2 magnesium ions per subunit.

2325:TKV RS03090
gene id: 2325:TKV_RS03090
uniprot id: A0A097APT1
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

2325:TKV RS08960
gene id: 2325:TKV_RS08960
uniprot id: A0A097AT29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

2325:TKV RS11165
gene id: 2325:TKV_RS11165
uniprot id: A0A097AUE0
names: Similarity
messages: Belongs to the GerABKA family.

2325:TKV RS09690
gene id: 2325:TKV_RS09690
uniprot id: A0A097ATL2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

2325:TKV RS09905
gene id: 2325:TKV_RS09905
uniprot id: A0A097ATK3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

2325:TKV RS11870
gene id: 2325:TKV_RS11870
uniprot id: A0A097AUS8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated exonuclease Cas4 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).
messages: Mg(2+) or Mn(2+) required for ssDNA cleavage activity.

2325:TKV RS08310
gene id: 2325:TKV_RS08310
uniprot id: A0A097ASR5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gluconeogenesis factor family.
messages: Cytoplasm
messages: Required for morphogenesis under gluconeogenic growth conditions.

2325:TKV RS05335
gene id: 2325:TKV_RS05335
uniprot id: A0A097AR30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

2325:TKV RS00870
gene id: 2325:TKV_RS00870
uniprot id: A0A097ANI6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

2325:TKV RS07935
gene id: 2325:TKV_RS07935
uniprot id: A0A097ASI6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Membrane

2325:TKV RS00475
gene id: 2325:TKV_RS00475
uniprot id: A0A097ANA8
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-I family.

2325:TKV RS09095
gene id: 2325:TKV_RS09095
uniprot id: A0A097AT93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

2325:TKV RS07875
gene id: 2325:TKV_RS07875
uniprot id: A0A097ASH4
names: Cofactor
messages: Binds 1 zinc ion per subunit.

2325:TKV RS03990
gene id: 2325:TKV_RS03990
uniprot id: A0A097AQC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

2325:TKV RS03085
gene id: 2325:TKV_RS03085
uniprot id: A0A097APV2
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

2325:TKV RS00670
gene id: 2325:TKV_RS00670
uniprot id: A0A097ANE7
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. HypB/HupM subfamily.

2325:TKV RS03120
gene id: 2325:TKV_RS03120
uniprot id: A0A097APS7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

2325:TKV RS11860
gene id: 2325:TKV_RS11860
uniprot id: A0A097AUS7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

2325:TKV RS00385
gene id: 2325:TKV_RS00385
uniprot id: A0A097AN88
names: Similarity
messages: Belongs to the class-I fumarase family.

2325:TKV RS05495
gene id: 2325:TKV_RS05495
uniprot id: A0A097AR59
names: Similarity
messages: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family.

2325:TKV RS05255
gene id: 2325:TKV_RS05255
uniprot id: A0A097AR14
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GDT1 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

2325:TKV RS03205
gene id: 2325:TKV_RS03205
uniprot id: A0A097APW0
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

2325:TKV RS00125
gene id: 2325:TKV_RS00125
uniprot id: A0A097AN48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

2325:TKV RS03125
gene id: 2325:TKV_RS03125
uniprot id: A0A097APT5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

2325:TKV RS06190
gene id: 2325:TKV_RS06190
uniprot id: A0A097ARK7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

2325:TKV RS06760
gene id: 2325:TKV_RS06760
uniprot id: A0A097ARW2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

2325:TKV RS05660
gene id: 2325:TKV_RS05660
uniprot id: A0A097ARA5
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

2325:TKV RS08945
gene id: 2325:TKV_RS08945
uniprot id: A0A097AT66
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

2325:TKV RS09400
gene id: 2325:TKV_RS09400
uniprot id: A0A097ATF5
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

2325:TKV RS01315
gene id: 2325:TKV_RS01315
uniprot id: A0A097ANU3
names: Subcellular Location Annotation
messages: Membrane

2325:TKV RS07480
gene id: 2325:TKV_RS07480
uniprot id: A0A097ASA6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

2325:TKV RS00970
gene id: 2325:TKV_RS00970
uniprot id: A0A097ANM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane

2325:TKV RS06575
gene id: 2325:TKV_RS06575
uniprot id: A0A097ARU6
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: Membrane

2325:TKV RS03605
gene id: 2325:TKV_RS03605
uniprot id: A0A097AQ37
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane
messages: This protein catalyzes the committed step to the synthesis of the acidic phospholipids.

2325:TKV RS01180
gene id: 2325:TKV_RS01180
uniprot id: A0A097ANQ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. C-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

2325:TKV RS09075
gene id: 2325:TKV_RS09075
uniprot id: A0A097AT86
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.
messages: May be involved in the biosynthesis of molybdopterin.

2325:TKV RS07450
gene id: 2325:TKV_RS07450
uniprot id: A0A097ASA3
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

2325:TKV RS04715
gene id: 2325:TKV_RS04715
uniprot id: A0A097AQT3
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

2325:TKV RS08785
gene id: 2325:TKV_RS08785
uniprot id: A0A097AT35
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division.

2325:TKV RS10840
gene id: 2325:TKV_RS10840
uniprot id: A0A097AU69
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

2325:TKV RS07505
gene id: 2325:TKV_RS07505
uniprot id: A0A097ASB0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2325:TKV RS11675
gene id: 2325:TKV_RS11675
uniprot id: A0A097AUP0
names: Subcellular Location Annotation
messages: Membrane

2325:TKV RS11095
gene id: 2325:TKV_RS11095
uniprot id: A0A097AUB7
names: Subcellular Location Annotation
messages: Membrane

2325:TKV RS00080
gene id: 2325:TKV_RS00080
uniprot id: A0A097AN41
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

2325:TKV RS05305
gene id: 2325:TKV_RS05305
uniprot id: A0A097AR24
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

2325:TKV RS06830
gene id: 2325:TKV_RS06830
uniprot id: A0A097ARZ7
names: Similarity
messages: Belongs to the asp23 family.

2325:TKV RS09070
gene id: 2325:TKV_RS09070
uniprot id: A0A097AT88
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

2325:TKV RS10360
gene id: 2325:TKV_RS10360
uniprot id: A0A097ATX4
names: Similarity
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Spore germination protein (SGP) (TC 2.A.3.9) family.

2325:TKV RS00810
gene id: 2325:TKV_RS00810
uniprot id: A0A097ANI1
names: Cofactor
names: Similarity
messages: Belongs to the AlaDH/PNT family.
messages: Binds 1 Mg(2+) ion per subunit.

2325:TKV RS04775
gene id: 2325:TKV_RS04775
uniprot id: A0A097AQR1
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

2325:TKV RS11260
gene id: 2325:TKV_RS11260
uniprot id: A0A097AUF3
names: Function
names: Similarity
messages: Belongs to the SpoVG family.
messages: Could be involved in septation.

2325:TKV RS11410
gene id: 2325:TKV_RS11410
uniprot id: A0A097AUF8
names: Similarity
messages: Belongs to the peptidase S41A family.

2325:TKV RS05965
gene id: 2325:TKV_RS05965
uniprot id: A0A097ARE9
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

2325:TKV RS01280
gene id: 2325:TKV_RS01280
uniprot id: A0A097ANS9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Cell membrane
messages: Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.
messages: Membrane

2325:TKV RS01600
gene id: 2325:TKV_RS01600
uniprot id: A0A097ANZ5
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

2325:TKV RS03055
gene id: 2325:TKV_RS03055
uniprot id: A0A097APS4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

2325:TKV RS04045
gene id: 2325:TKV_RS04045
uniprot id: A0A097AQG2
names: Similarity
messages: Belongs to the glycosyl hydrolase 65 family.

2325:TKV RS03545
gene id: 2325:TKV_RS03545
uniprot id: A0A097AQ27
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Amj family.
messages: Cell membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.

2325:TKV RS08755
gene id: 2325:TKV_RS08755
uniprot id: A0A097AT03
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

2325:TKV RS01225
gene id: 2325:TKV_RS01225
uniprot id: A0A097ANP9
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

2325:TKV RS06905
gene id: 2325:TKV_RS06905
uniprot id: A0A097AS11
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2325:TKV RS07620
gene id: 2325:TKV_RS07620
uniprot id: A0A097ASD9
names: Function
names: Similarity
messages: Belongs to the CobT family.
messages: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).

2325:TKV RS07815
gene id: 2325:TKV_RS07815
uniprot id: A0A097ASH7
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSP33 family.
messages: Cytoplasm
messages: Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.
messages: Under oxidizing conditions two disulfide bonds are formed involving the reactive cysteines. Under reducing conditions zinc is bound to the reactive cysteines and the protein is inactive.

2325:TKV RS10215
gene id: 2325:TKV_RS10215
uniprot id: A0A097ATU4
names: Activity Regulation
names: Function
names: Similarity
messages: Appears to be allosterically activated by the binding of pArg-containing polypeptides to the pArg-binding pocket localized in the C-terminal domain of McsB.
messages: Belongs to the ATP:guanido phosphotransferase family.
messages: Catalyzes the specific phosphorylation of arginine residues in proteins.

2325:TKV RS08865
gene id: 2325:TKV_RS08865
uniprot id: A0A097AT41
names: Function
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.

2325:TKV RS03570
gene id: 2325:TKV_RS03570
uniprot id: A0A097AQ49
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
messages: Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
messages: Homodimer.

2325:TKV RS10830
gene id: 2325:TKV_RS10830
uniprot id: A0A097AU60
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2325:TKV RS04795
gene id: 2325:TKV_RS04795
uniprot id: A0A097AQT2
names: Similarity
names: Subunit
messages: Belongs to the UPF0210 family.
messages: Homodimer.

2325:TKV RS07295
gene id: 2325:TKV_RS07295
uniprot id: A0A097AS80
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SepF family.
messages: Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
messages: Cytoplasm
messages: Homodimer. Interacts with FtsZ.

2325:TKV RS07690
gene id: 2325:TKV_RS07690
uniprot id: A0A097ASH8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
messages: Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
messages: Homodimer.

2325:TKV RS08300
gene id: 2325:TKV_RS08300
uniprot id: A0A097ASR9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 1 family.
messages: Cell membrane

2325:TKV RS09990
gene id: 2325:TKV_RS09990
uniprot id: A0A097ATP1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

2325:TKV RS06935
gene id: 2325:TKV_RS06935
uniprot id: A0A097AS16
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

2325:TKV RS08770
gene id: 2325:TKV_RS08770
uniprot id: A0A097AT19
names: Similarity
messages: Belongs to the peptidase S41A family.

2325:TKV RS08440
gene id: 2325:TKV_RS08440
uniprot id: A0A097ASX1
names: Similarity
messages: Belongs to the CRISPR-associated Csm3 family.

2325:TKV RS04195
gene id: 2325:TKV_RS04195
uniprot id: A0A097AQJ2
names: Similarity
messages: Belongs to the peptidase S49 family.

2325:TKV RS09945
gene id: 2325:TKV_RS09945
uniprot id: A0A097ATN1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

2325:TKV RS06870
gene id: 2325:TKV_RS06870
uniprot id: A0A097AS04
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

2325:TKV RS06275
gene id: 2325:TKV_RS06275
uniprot id: A0A097ARN7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Homohexamer. Forms a ring that surrounds DNA.
messages: Membrane

2325:TKV RS04285
gene id: 2325:TKV_RS04285
uniprot id: A0A097AQG5
names: Subcellular Location Annotation
messages: Membrane

2325:TKV RS11355
gene id: 2325:TKV_RS11355
uniprot id: A0A097AUH2
names: Similarity
messages: Belongs to the PHP hydrolase family. HisK subfamily.

2325:TKV RS05855
gene id: 2325:TKV_RS05855
uniprot id: A0A097ARE7
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

2325:TKV RS08655
gene id: 2325:TKV_RS08655
uniprot id: A0A097ASW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

2325:TKV RS01915
gene id: 2325:TKV_RS01915
uniprot id: A0A097AP70
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

2325:TKV RS03365
gene id: 2325:TKV_RS03365
uniprot id: A0A097APZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

2325:TKV RS11670
gene id: 2325:TKV_RS11670
uniprot id: A0A097AUN7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

2325:TKV RS10865
gene id: 2325:TKV_RS10865
uniprot id: A0A097AU74
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

2325:TKV RS01185
gene id: 2325:TKV_RS01185
uniprot id: A0A097ANQ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. N-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

2325:TKV RS11985
gene id: 2325:TKV_RS11985
uniprot id: A0A097AUV0
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

2325:TKV RS09965
gene id: 2325:TKV_RS09965
uniprot id: A0A097ATN0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

2325:TKV RS00740
gene id: 2325:TKV_RS00740
uniprot id: A0A097ANG1
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

2325:TKV RS08420
gene id: 2325:TKV_RS08420
uniprot id: A0A097ASU2
names: Similarity
messages: Belongs to the Fur family.

2325:TKV RS08390
gene id: 2325:TKV_RS08390
uniprot id: A0A097ASW2
names: Function
names: Subcellular Location Annotation
messages: Chaperone that serves for the intracellular sequestration and transport of Cu(+). Delivers Cu(+) to the copper-exporting P-type ATPase A (CopA).
messages: Cytoplasm

2325:TKV RS08750
gene id: 2325:TKV_RS08750
uniprot id: A0A097ASY8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

2325:TKV RS05045
gene id: 2325:TKV_RS05045
uniprot id: A0A097AR05
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

2325:TKV RS01530
gene id: 2325:TKV_RS01530
uniprot id: A0A097ANY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

2325:TKV RS10090
gene id: 2325:TKV_RS10090
uniprot id: A0A097ATQ8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

2325:TKV RS00950
gene id: 2325:TKV_RS00950
uniprot id: A0A097ANL1
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

2325:TKV RS12040
gene id: 2325:TKV_RS12040
uniprot id: A0A097AUR1
names: Function
names: Similarity
names: Subunit
messages: Catalyzes the ATP-dependent polymerization of arginine and aspartate to multi-L-arginyl-poly-L-aspartic acid (cyanophycin; a water-insoluble reserve polymer).
messages: Homodimer.
messages: In the C-terminal section; belongs to the MurCDEF family.

2325:TKV RS09935
gene id: 2325:TKV_RS09935
uniprot id: A0A097ATN2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.
messages: Cytoplasm
messages: Monomer.

2325:TKV RS06160
gene id: 2325:TKV_RS06160
uniprot id: A0A097ARK9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

2325:TKV RS01700
gene id: 2325:TKV_RS01700
uniprot id: A0A097AP16
names: Cofactor
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

2325:TKV RS06950
gene id: 2325:TKV_RS06950
uniprot id: A0A097AS19
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

2325:TKV RS05510
gene id: 2325:TKV_RS05510
uniprot id: A0A097AR74
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

2325:TKV RS05820
gene id: 2325:TKV_RS05820
uniprot id: A0A097ARC2
names: Similarity
messages: Belongs to the asp23 family.

2325:TKV RS04095
gene id: 2325:TKV_RS04095
uniprot id: A0A097AQH2
names: Function
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family. DapH subfamily.
messages: Catalyzes the transfer of an acetyl group from acetyl-CoA to tetrahydrodipicolinate.

2325:TKV RS04470
gene id: 2325:TKV_RS04470
uniprot id: A0A097AQP3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

2325:TKV RS09960
gene id: 2325:TKV_RS09960
uniprot id: A0A097ATN6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

2325:TKV RS06650
gene id: 2325:TKV_RS06650
uniprot id: A0A097ARW1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.
messages: Cytoplasm
messages: Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity.

2325:TKV RS02880
gene id: 2325:TKV_RS02880
uniprot id: A0A097APP2
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

2325:TKV RS06290
gene id: 2325:TKV_RS06290
uniprot id: A0A097ARM4
names: Function
names: Similarity
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids threonine, isoleucine and methionine.

2325:TKV RS09290
gene id: 2325:TKV_RS09290
uniprot id: A0A097ATC5
names: Similarity
messages: Belongs to the GcvH family.

2325:TKV RS03460
gene id: 2325:TKV_RS03460
uniprot id: A0A097AQ28
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PdxS/SNZ family.
messages: Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
messages: In the presence of PdxT, forms a dodecamer of heterodimers.

2325:TKV RS05975
gene id: 2325:TKV_RS05975
uniprot id: A0A097ARH0
names: Function
names: Similarity
messages: Belongs to the anti-sigma-factor family.
messages: Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.

2325:TKV RS02795
gene id: 2325:TKV_RS02795
uniprot id: A0A097APM6
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

2325:TKV RS02935
gene id: 2325:TKV_RS02935
uniprot id: A0A097APT3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

2325:TKV RS06660
gene id: 2325:TKV_RS06660
uniprot id: A0A097ARU2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

2325:TKV RS02620
gene id: 2325:TKV_RS02620
uniprot id: A0A097API5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acetylates the N-terminal alanine of ribosomal protein S18.
messages: Belongs to the acetyltransferase family. RimI subfamily.
messages: Cytoplasm

2325:TKV RS06735
gene id: 2325:TKV_RS06735
uniprot id: A0A097ARV7
names: Similarity
messages: Belongs to the fabD family.

2325:TKV RS00095
gene id: 2325:TKV_RS00095
uniprot id: A0A097AN43
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2325:TKV RS08475
gene id: 2325:TKV_RS08475
uniprot id: A0A097ASV6
names: Similarity
messages: Belongs to the tRNA methyltransferase O family.

2325:TKV RS05970
gene id: 2325:TKV_RS05970
uniprot id: A0A097ARH8
names: Function
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.
messages: In the phosphorylated form it could act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma f from inhibition.

2325:TKV RS02155
gene id: 2325:TKV_RS02155
uniprot id: A0A097AP82
names: Subcellular Location Annotation
messages: Membrane

2325:TKV RS00755
gene id: 2325:TKV_RS00755
uniprot id: A0A097ANI2
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

2325:TKV RS11155
gene id: 2325:TKV_RS11155
uniprot id: A0A097AUD1
names: Similarity
messages: Belongs to the GerABKC lipoprotein family.

2325:TKV RS11855
gene id: 2325:TKV_RS11855
uniprot id: A0A097AUM9
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated protein Cas6/Cse3/CasE family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).

2325:TKV RS04410
gene id: 2325:TKV_RS04410
uniprot id: A0A097AQL0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. MrdB/RodA subfamily.
messages: Cell membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell wall elongation.

2325:TKV RS00425
gene id: 2325:TKV_RS00425
uniprot id: A0A097AN94
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

2325:TKV RS08650
gene id: 2325:TKV_RS08650
uniprot id: A0A097ASZ3
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

2325:TKV RS12010
gene id: 2325:TKV_RS12010
uniprot id: A0A097AUV5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

2325:TKV RS10240
gene id: 2325:TKV_RS10240
uniprot id: A0A097ATU9
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.

2325:TKV RS02145
gene id: 2325:TKV_RS02145
uniprot id: A0A097AP91
names: Similarity
messages: Belongs to the BMP lipoprotein family.

2325:TKV RS07020
gene id: 2325:TKV_RS07020
uniprot id: A0A097AS28
names: Function
names: Similarity
names: Subunit
messages: Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
messages: Homodimer and homohexamer; in equilibrium.
messages: Regulates transcriptional attenuation of the pyrimidine nucleotide (pyr) operon by binding in a uridine-dependent manner to specific sites on pyr mRNA. This disrupts an antiterminator hairpin in the RNA and favors formation of a downstream transcription terminator, leading to a reduced expression of downstream genes.

2325:TKV RS00225
gene id: 2325:TKV_RS00225
uniprot id: A0A097ASQ9
names: Similarity
messages: Belongs to the UPF0236 family.

2325:TKV RS06410
gene id: 2325:TKV_RS06410
uniprot id: A0A097ARR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

2325:TKV RS07735
gene id: 2325:TKV_RS07735
uniprot id: A0A097ASI8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

2325:TKV RS07200
gene id: 2325:TKV_RS07200
uniprot id: A0A097AS43
names: Similarity
messages: Belongs to the UPF0047 family.

2325:TKV RS08955
gene id: 2325:TKV_RS08955
uniprot id: A0A097AT64
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

2325:TKV RS11160
gene id: 2325:TKV_RS11160
uniprot id: A0A097AUB4
names: Similarity
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Spore germination protein (SGP) (TC 2.A.3.9) family.

2325:TKV RS00890
gene id: 2325:TKV_RS00890
uniprot id: A0A097ANJ0
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

2325:TKV RS12530
gene id: 2325:TKV_RS12530
uniprot id: A0A097ATU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0291 family.
messages: Cytoplasm

2325:TKV RS07280
gene id: 2325:TKV_RS07280
uniprot id: A0A097AS59
names: Subcellular Location Annotation
messages: Cytoplasm

2325:TKV RS11100
gene id: 2325:TKV_RS11100
uniprot id: A0A097AU98
names: Subcellular Location Annotation
messages: Membrane

2325:TKV RS06585
gene id: 2325:TKV_RS06585
uniprot id: A0A097ARS8
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

2325:TKV RS10450
gene id: 2325:TKV_RS10450
uniprot id: A0A097ATX5
names: Similarity
messages: Belongs to the zinc-associated anti-sigma factor (ZAS) superfamily. Anti-sigma-W factor family.

2325:TKV RS07440
gene id: 2325:TKV_RS07440
uniprot id: A0A097ASA1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PstS family.
messages: Cell membrane
messages: Involved in the system for phosphate transport across the cytoplasmic membrane.
messages: Membrane
messages: Part of the ABC transporter complex PstSACB involved in phosphate import.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

2325:TKV RS06285
gene id: 2325:TKV_RS06285
uniprot id: A0A097ARN5
names: Similarity
messages: Belongs to the peptidase S14 family.

2325:TKV RS06730
gene id: 2325:TKV_RS06730
uniprot id: A0A097ARX9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

2325:TKV RS09360
gene id: 2325:TKV_RS09360
uniprot id: A0A097ATD5
names: Cofactor
names: Function
names: Subunit
messages: Binds 2 [4Fe-4S] clusters. In this family the first cluster has a non-standard and varying [4Fe-4S] binding motif CX(2)CX(2)CX(4-5)CP.
messages: Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates.
messages: Heterodimer of the IorA and IorB subunits.

2325:TKV RS06755
gene id: 2325:TKV_RS06755
uniprot id: A0A097ARY4
names: Function
names: Similarity
messages: Belongs to the FapR family.
messages: Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism.

2325:TKV RS06720
gene id: 2325:TKV_RS06720
uniprot id: A0A097ARX3
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

2325:TKV RS11865
gene id: 2325:TKV_RS11865
uniprot id: A0A097AUN6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

2325:TKV RS06680
gene id: 2325:TKV_RS06680
uniprot id: A0A097ARW9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

2325:TKV RS09055
gene id: 2325:TKV_RS09055
uniprot id: A0A097AT85
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

2325:TKV RS08435
gene id: 2325:TKV_RS08435
uniprot id: A0A097ASU0
names: Similarity
messages: Belongs to the CRISPR-associated Csm4 family.

2325:TKV RS01490
gene id: 2325:TKV_RS01490
uniprot id: A0A097ANW4
names: Function
names: Similarity
messages: Belongs to the Thz kinase family.
messages: Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).

2325:TKV RS05415
gene id: 2325:TKV_RS05415
uniprot id: A0A097AR43
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

2325:TKV RS01710
gene id: 2325:TKV_RS01710
uniprot id: A0A097AP29
names: Subcellular Location Annotation
messages: Membrane

2325:TKV RS01275
gene id: 2325:TKV_RS01275
uniprot id: A0A097ANS8
names: Similarity
messages: Belongs to the iron-containing alcohol dehydrogenase family.

2325:TKV RS11885
gene id: 2325:TKV_RS11885
uniprot id: A0A097AUT2
names: Function
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).

2325:TKV RS01075
gene id: 2325:TKV_RS01075
uniprot id: A0A097ANM1
names: Similarity
messages: Belongs to the threonine aldolase family.

2325:TKV RS10355
gene id: 2325:TKV_RS10355
uniprot id: A0A097ATW3
names: Similarity
messages: Belongs to the GerABKA family.

2325:TKV RS03285
gene id: 2325:TKV_RS03285
uniprot id: A0A097APW7
names: Subcellular Location Annotation
messages: Membrane

2325:TKV RS04865
gene id: 2325:TKV_RS04865
uniprot id: A0A097AQW7
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

2325:TKV RS09975
gene id: 2325:TKV_RS09975
uniprot id: A0A097ATP2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

2325:TKV RS02870
gene id: 2325:TKV_RS02870
uniprot id: A0A097APP1
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

2325:TKV RS04925
gene id: 2325:TKV_RS04925
uniprot id: A0A097AQX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

2325:TKV RS08170
gene id: 2325:TKV_RS08170
uniprot id: A0A097ASP6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M20B family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Cleaves the N-terminal amino acid of tripeptides.
messages: Cytoplasm

2325:TKV RS04860
gene id: 2325:TKV_RS04860
uniprot id: A0A097AQU5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

2325:TKV RS01360
gene id: 2325:TKV_RS01360
uniprot id: A0A097ANU2
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

2325:TKV RS07855
gene id: 2325:TKV_RS07855
uniprot id: A0A097ASH6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

2325:TKV RS08485
gene id: 2325:TKV_RS08485
uniprot id: A0A097ASV0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

2325:TKV RS11395
gene id: 2325:TKV_RS11395
uniprot id: A0A097AUI6
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

2325:TKV RS12110
gene id: 2325:TKV_RS12110
uniprot id: A0A097AUX4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

2325:TKV RS05895
gene id: 2325:TKV_RS05895
uniprot id: A0A097ARD4
names: Cofactor
names: Function
names: Subcellular Location Annotation
messages: Binds 1 Ca(2+) ion per subunit.
messages: Cytoplasm
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

2325:TKV RS11295
gene id: 2325:TKV_RS11295
uniprot id: A0A097AUG4
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

2325:TKV RS10540
gene id: 2325:TKV_RS10540
uniprot id: A0A097AU02
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

2325:TKV RS04810
gene id: 2325:TKV_RS04810
uniprot id: A0A097AQR2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

2325:TKV RS08085
gene id: 2325:TKV_RS08085
uniprot id: A0A097ASM6
names: Cofactor
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

2325:TKV RS09205
gene id: 2325:TKV_RS09205
uniprot id: A0A097ATA9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.

2325:TKV RS04110
gene id: 2325:TKV_RS04110
uniprot id: A0A097AQF2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2325:TKV RS08965
gene id: 2325:TKV_RS08965
uniprot id: A0A097AT55
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

2325:TKV RS03130
gene id: 2325:TKV_RS03130
uniprot id: A0A097APU0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

2325:TKV RS04140
gene id: 2325:TKV_RS04140
uniprot id: A0A097AQE4
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M38 family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Carboxylation allows a single lysine to coordinate two zinc ions.
messages: Catalyzes the hydrolytic cleavage of a subset of L-isoaspartyl (L-beta-aspartyl) dipeptides. Used to degrade proteins damaged by L-isoaspartyl residues formation.
messages: Cytoplasm

2325:TKV RS09045
gene id: 2325:TKV_RS09045
uniprot id: A0A097AT83
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

2325:TKV RS05320
gene id: 2325:TKV_RS05320
uniprot id: A0A097AR38
names: Similarity
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.

2325:TKV RS00065
gene id: 2325:TKV_RS00065
uniprot id: A0A097AN64
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

2325:TKV RS10155
gene id: 2325:TKV_RS10155
uniprot id: A0A097ATS0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

2325:TKV RS08940
gene id: 2325:TKV_RS08940
uniprot id: A0A097AT49
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the PRA-PH family.
messages: In the N-terminal section; belongs to the PRA-CH family.

2325:TKV RS11085
gene id: 2325:TKV_RS11085
uniprot id: A0A097AUA1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

2325:TKV RS05670
gene id: 2325:TKV_RS05670
uniprot id: A0A097AR92
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2325:TKV RS00535
gene id: 2325:TKV_RS00535
uniprot id: A0A097AND9
names: Subcellular Location Annotation
messages: Membrane

2325:TKV RS02790
gene id: 2325:TKV_RS02790
uniprot id: A0A097APM8
names: Caution
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2325:TKV RS01580
gene id: 2325:TKV_RS01580
uniprot id: A0A097ANZ2
names: Similarity
messages: Belongs to the CobH/CbiC family.

2325:TKV RS02350
gene id: 2325:TKV_RS02350
uniprot id: A0A097APE1
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

2325:TKV RS07240
gene id: 2325:TKV_RS07240
uniprot id: A0A097AS70
names: Similarity
messages: Belongs to the TrpC family.

2325:TKV RS00090
gene id: 2325:TKV_RS00090
uniprot id: A0A097AN70
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

2325:TKV RS04005
gene id: 2325:TKV_RS04005
uniprot id: A0A097AQD8
names: Function
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.

2325:TKV RS01005
gene id: 2325:TKV_RS01005
uniprot id: A0A097ANL8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Could methylate the ribose at the nucleotide 34 wobble position in tRNA.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2325:TKV RS06215
gene id: 2325:TKV_RS06215
uniprot id: A0A097ARL2
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

2325:TKV RS01195
gene id: 2325:TKV_RS01195
uniprot id: A0A097ANR7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

2325:TKV RS00190
gene id: 2325:TKV_RS00190
uniprot id: A0A097AN57
names: Similarity
messages: Belongs to the alkaline phosphatase family.

2325:TKV RS06780
gene id: 2325:TKV_RS06780
uniprot id: A0A097ARY7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TmcAL family.
messages: Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of elongator tRNA(Met), using acetate and ATP as substrates. First activates an acetate ion to form acetyladenylate (Ac-AMP) and then transfers the acetyl group to tRNA to form ac(4)C34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2325:TKV RS00045
gene id: 2325:TKV_RS00045
uniprot id: A0A097AN31
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

2325:TKV RS00020
gene id: 2325:TKV_RS00020
uniprot id: A0A097AN27
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

2325:TKV RS11070
gene id: 2325:TKV_RS11070
uniprot id: A0A097AUB1
names: Similarity
messages: Belongs to the peptidase C40 family.

2325:TKV RS07025
gene id: 2325:TKV_RS07025
uniprot id: A0A097AS32
names: Similarity
messages: Belongs to the HypE family.

2325:TKV RS01200
gene id: 2325:TKV_RS01200
uniprot id: A0A097ASQ9
names: Similarity
messages: Belongs to the UPF0236 family.

2325:TKV RS07310
gene id: 2325:TKV_RS07310
uniprot id: A0A097AS81
names: Similarity
messages: Belongs to the RutC family.

2325:TKV RS06370
gene id: 2325:TKV_RS06370
uniprot id: A0A097ARN1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-C family. PolC subfamily.
messages: Cytoplasm
messages: Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

2325:TKV RS00615
gene id: 2325:TKV_RS00615
uniprot id: A0A097AND6
names: Subcellular Location Annotation
messages: Membrane

2325:TKV RS01480
gene id: 2325:TKV_RS01480
uniprot id: A0A097ANX0
names: Similarity
messages: Belongs to the ThiD family.

2325:TKV RS09465
gene id: 2325:TKV_RS09465
uniprot id: A0A097ATF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CotF family.
messages: Spore coat

2325:TKV RS05605
gene id: 2325:TKV_RS05605
uniprot id: A0A097ARA4
names: Similarity
messages: Belongs to the UPF0297 family.

2325:TKV RS03140
gene id: 2325:TKV_RS03140
uniprot id: A0A097APU3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

2325:TKV RS07360
gene id: 2325:TKV_RS07360
uniprot id: A0A097AS88
names: Function
names: Subcellular Location Annotation
messages: ATPase. Has a role at an early stage in the morphogenesis of the spore coat.
messages: Cytoplasm

2325:TKV RS02655
gene id: 2325:TKV_RS02655
uniprot id: A0A097APM5
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

2325:TKV RS10055
gene id: 2325:TKV_RS10055
uniprot id: A0A097ATR0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

2325:TKV RS00255
gene id: 2325:TKV_RS00255
uniprot id: A0A097AN68
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane

2325:TKV RS01665
gene id: 2325:TKV_RS01665
uniprot id: A0A097AP18
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CbiM family.
messages: Cell membrane
messages: Forms an energy-coupling factor (ECF) transporter complex composed of an ATP-binding protein (A component, CbiO), a transmembrane protein (T component, CbiQ) and 2 possible substrate-capture proteins (S components, CbiM and CbiN) of unknown stoichimetry.
messages: Membrane
messages: Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import.

2325:TKV RS10185
gene id: 2325:TKV_RS10185
uniprot id: A0A097ATS8
names: Similarity
messages: Belongs to the ycf81 family.

2325:TKV RS09050
gene id: 2325:TKV_RS09050
uniprot id: A0A097AT81
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

2325:TKV RS05105
gene id: 2325:TKV_RS05105
uniprot id: A0A097AQY6
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

2325:TKV RS07995
gene id: 2325:TKV_RS07995
uniprot id: A0A097ASJ1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

2325:TKV RS08295
gene id: 2325:TKV_RS08295
uniprot id: A0A097ASR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

2325:TKV RS03105
gene id: 2325:TKV_RS03105
uniprot id: A0A097APT4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

2325:TKV RS06900
gene id: 2325:TKV_RS06900
uniprot id: A0A097AS08
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

2325:TKV RS08730
gene id: 2325:TKV_RS08730
uniprot id: A0A097ASZ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

2325:TKV RS10320
gene id: 2325:TKV_RS10320
uniprot id: A0A097ATV2
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

2325:TKV RS06670
gene id: 2325:TKV_RS06670
uniprot id: A0A097ARW4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A probable RNA chaperone. Forms a complex with KhpB which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm
messages: Forms a complex with KhpB.

2325:TKV RS06795
gene id: 2325:TKV_RS06795
uniprot id: A0A097ARY8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

2325:TKV RS02785
gene id: 2325:TKV_RS02785
uniprot id: A0A097APL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

2325:TKV RS07270
gene id: 2325:TKV_RS07270
uniprot id: A0A097AS76
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

2325:TKV RS09595
gene id: 2325:TKV_RS09595
uniprot id: A0A097ATF1
names: Subcellular Location Annotation
messages: Membrane

2325:TKV RS12115
gene id: 2325:TKV_RS12115
uniprot id: A0A097AUX6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

2325:TKV RS04485
gene id: 2325:TKV_RS04485
uniprot id: A0A097AQM7
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

2325:TKV RS01175
gene id: 2325:TKV_RS01175
uniprot id: A0A097ANN9
names: Caution
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FBP aldolase/phosphatase family.
messages: Catalyzes two subsequent steps in gluconeogenesis: the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3-phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P).
messages: Consists of a single catalytic domain, but remodels its active-site architecture via a large structural change to exhibit dual activities.
messages: Homooctamer; dimer of tetramers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2325:TKV RS05680
gene id: 2325:TKV_RS05680
uniprot id: A0A097ARB7
names: Similarity
messages: Belongs to the GSP E family.

2325:TKV RS09910
gene id: 2325:TKV_RS09910
uniprot id: A0A097ATM7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

2325:TKV RS05375
gene id: 2325:TKV_RS05375
uniprot id: A0A097AR62
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

2325:TKV RS05760
gene id: 2325:TKV_RS05760
uniprot id: A0A097ARC7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

2325:TKV RS07375
gene id: 2325:TKV_RS07375
uniprot id: A0A097AS91
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

2325:TKV RS02740
gene id: 2325:TKV_RS02740
uniprot id: A0A097APL8
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

2325:TKV RS02440
gene id: 2325:TKV_RS02440
uniprot id: A0A097APF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

2325:TKV RS04920
gene id: 2325:TKV_RS04920
uniprot id: A0A097AQV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

2325:TKV RS07490
gene id: 2325:TKV_RS07490
uniprot id: A0A097ASA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sbp family.
messages: Cell membrane

2325:TKV RS06460
gene id: 2325:TKV_RS06460
uniprot id: A0A097ARS2
names: Function
names: Similarity
messages: Belongs to the CheD family.
messages: Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.

2325:TKV RS11255
gene id: 2325:TKV_RS11255
uniprot id: A0A097AUC5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2325:TKV RS10820
gene id: 2325:TKV_RS10820
uniprot id: A0A097AU56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

2325:TKV RS07755
gene id: 2325:TKV_RS07755
uniprot id: A0A097ASF4
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2325:TKV RS03975
gene id: 2325:TKV_RS03975
uniprot id: A0A097AQE7
names: Similarity
messages: Belongs to the glycosyl hydrolase 65 family.

2325:TKV RS03340
gene id: 2325:TKV_RS03340
uniprot id: A0A097APZ0
names: Subcellular Location Annotation
messages: Membrane

2325:TKV RS03075
gene id: 2325:TKV_RS03075
uniprot id: A0A097APS5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

2325:TKV RS00705
gene id: 2325:TKV_RS00705
uniprot id: A0A097ANH2
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

2325:TKV RS06600
gene id: 2325:TKV_RS06600
uniprot id: A0A097ARV1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CodY family.
messages: Cytoplasm
messages: DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor.

2325:TKV RS11825
gene id: 2325:TKV_RS11825
uniprot id: A0A097AUR8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

2325:TKV RS11200
gene id: 2325:TKV_RS11200
uniprot id: A0A097ASQ9
names: Similarity
messages: Belongs to the UPF0236 family.

2325:TKV RS07820
gene id: 2325:TKV_RS07820
uniprot id: A0A097ASG5
names: Subcellular Location Annotation
messages: Cytoplasm

2325:TKV RS02895
gene id: 2325:TKV_RS02895
uniprot id: A0A097APP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

2325:TKV RS09420
gene id: 2325:TKV_RS09420
uniprot id: A0A097ATE6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the adenylate cyclase family. DacA/CdaA subfamily.
messages: Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.
messages: Probably a homodimer.

2325:TKV RS04365
gene id: 2325:TKV_RS04365
uniprot id: A0A097AQI0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

2325:TKV RS06405
gene id: 2325:TKV_RS06405
uniprot id: A0A097ARR0
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2325:TKV RS09010
gene id: 2325:TKV_RS09010
uniprot id: A0A097AT65
names: Subcellular Location Annotation
messages: Membrane

2325:TKV RS05265
gene id: 2325:TKV_RS05265
uniprot id: A0A097AR46
names: Function
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.
messages: Transcriptional repressor of xylose-utilizing enzymes.

2325:TKV RS04445
gene id: 2325:TKV_RS04445
uniprot id: A0A097AQN7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
messages: Cytoplasm

2325:TKV RS05485
gene id: 2325:TKV_RS05485
uniprot id: A0A097AR68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

2325:TKV RS04370
gene id: 2325:TKV_RS04370
uniprot id: A0A097AQM2
names: Similarity
messages: Belongs to the UPF0758 family.

2325:TKV RS06175
gene id: 2325:TKV_RS06175
uniprot id: A0A097ARL8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

2325:TKV RS08070
gene id: 2325:TKV_RS08070
uniprot id: A0A097ASK7
names: Similarity
messages: Belongs to the Mg-chelatase subunit H family.

2325:TKV RS10255
gene id: 2325:TKV_RS10255
uniprot id: A0A097ATU0
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

2325:TKV RS11620
gene id: 2325:TKV_RS11620
uniprot id: A0A097AUM7
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
messages: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.

2325:TKV RS05310
gene id: 2325:TKV_RS05310
uniprot id: A0A097AR37
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
messages: Monomer.

2325:TKV RS09030
gene id: 2325:TKV_RS09030
uniprot id: A0A097AT44
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2325:TKV RS00335
gene id: 2325:TKV_RS00335
uniprot id: A0A097ANA4
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

2325:TKV RS09675
gene id: 2325:TKV_RS09675
uniprot id: A0A097ATJ8
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

2325:TKV RS06505
gene id: 2325:TKV_RS06505
uniprot id: A0A097ART1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type III secretion exporter family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

2325:TKV RS04415
gene id: 2325:TKV_RS04415
uniprot id: A0A097AQJ0
names: Caution
names: Function
names: Similarity
messages: Belongs to the methylglyoxal synthase family.
messages: Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2325:TKV RS07365
gene id: 2325:TKV_RS07365
uniprot id: A0A097AS87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

2325:TKV RS10165
gene id: 2325:TKV_RS10165
uniprot id: A0A097ATT4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

2325:TKV RS05615
gene id: 2325:TKV_RS05615
uniprot id: A0A097AR93
names: Similarity
messages: Belongs to the UPF0473 family.

2325:TKV RS01660
gene id: 2325:TKV_RS01660
uniprot id: A0A097ANZ9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

2325:TKV RS02480
gene id: 2325:TKV_RS02480
uniprot id: A0A097APG2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

2325:TKV RS06895
gene id: 2325:TKV_RS06895
uniprot id: A0A097AS10
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

2325:TKV RS05620
gene id: 2325:TKV_RS05620
uniprot id: A0A097AR82
names: Similarity
messages: Belongs to the Fur family.

2325:TKV RS09940
gene id: 2325:TKV_RS09940
uniprot id: A0A097ATM6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

2325:TKV RS00010
gene id: 2325:TKV_RS00010
uniprot id: A0A097AN26
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

2325:TKV RS12055
gene id: 2325:TKV_RS12055
uniprot id: A0A097AUW5
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.

2325:TKV RS06510
gene id: 2325:TKV_RS06510
uniprot id: A0A097ART3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliR/MopE/SpaR family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

2325:TKV RS08430
gene id: 2325:TKV_RS08430
uniprot id: A0A097ASS5
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated Csm5 family.
messages: This subunit might be involved in maturation of a crRNA intermediate to its mature form.

2325:TKV RS10740
gene id: 2325:TKV_RS10740
uniprot id: A0A097AU49
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

2325:TKV RS05645
gene id: 2325:TKV_RS05645
uniprot id: A0A097AR87
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family.
messages: Catalyzes the methylation of 5-hydroxyuridine (ho5U) to form 5-methoxyuridine (mo5U) at position 34 in tRNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2325:TKV RS00245
gene id: 2325:TKV_RS00245
uniprot id: A0A097AN69
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

2325:TKV RS04325
gene id: 2325:TKV_RS04325
uniprot id: A0A097AQG6
names: Similarity
messages: Belongs to the NadC/ModD family.

2325:TKV RS01090
gene id: 2325:TKV_RS01090
uniprot id: A0A097ANP4
names: Similarity
messages: Belongs to the Fur family.

2325:TKV RS07530
gene id: 2325:TKV_RS07530
uniprot id: A0A097ASB4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

2325:TKV RS00240
gene id: 2325:TKV_RS00240
uniprot id: A0A097AN67
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

2325:TKV RS09890
gene id: 2325:TKV_RS09890
uniprot id: A0A097ATL8
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

2325:TKV RS00690
gene id: 2325:TKV_RS00690
uniprot id: A0A097ANF2
names: Similarity
messages: Belongs to the HypD family.

2325:TKV RS10070
gene id: 2325:TKV_RS10070
uniprot id: A0A097ATQ7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

2325:TKV RS00885
gene id: 2325:TKV_RS00885
uniprot id: A0A097ANI8
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

2325:TKV RS01625
gene id: 2325:TKV_RS01625
uniprot id: A0A097AP00
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

2325:TKV RS00610
gene id: 2325:TKV_RS00610
uniprot id: A0A097ANF3
names: Similarity
messages: Belongs to the AAA ATPase family.
messages: In the C-terminal section; belongs to the peptidase M41 family.

2325:TKV RS07940
gene id: 2325:TKV_RS07940
uniprot id: A0A097ASK0
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

2325:TKV RS00075
gene id: 2325:TKV_RS00075
uniprot id: A0A097AN37
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

2325:TKV RS00725
gene id: 2325:TKV_RS00725
uniprot id: A0A097ANF6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.

2325:TKV RS04225
gene id: 2325:TKV_RS04225
uniprot id: A0A097AQH1
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.

2325:TKV RS03035
gene id: 2325:TKV_RS03035
uniprot id: A0A097APS0
names: Subcellular Location Annotation
messages: Membrane

2325:TKV RS11425
gene id: 2325:TKV_RS11425
uniprot id: A0A097AUF7
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

2325:TKV RS01380
gene id: 2325:TKV_RS01380
uniprot id: A0A097ANV1
names: Similarity
messages: Belongs to the UPF0111 family.

2325:TKV RS05885
gene id: 2325:TKV_RS05885
uniprot id: A0A097ARF1
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

2325:TKV RS06210
gene id: 2325:TKV_RS06210
uniprot id: A0A097ARM0
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

2325:TKV RS04760
gene id: 2325:TKV_RS04760
uniprot id: A0A097AQQ2
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

2325:TKV RS08760
gene id: 2325:TKV_RS08760
uniprot id: A0A097AT30
names: Similarity
messages: Belongs to the ComB family.

2325:TKV RS10855
gene id: 2325:TKV_RS10855
uniprot id: A0A097AU66
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

2325:TKV RS05835
gene id: 2325:TKV_RS05835
uniprot id: A0A097ARE0
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

2325:TKV RS08250
gene id: 2325:TKV_RS08250
uniprot id: A0A097ASR0
names: Function
names: Similarity
messages: Belongs to the WhiA family.
messages: Involved in cell division and chromosome segregation.

2325:TKV RS09555
gene id: 2325:TKV_RS09555
uniprot id: A0A097ATH1
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

2325:TKV RS01570
gene id: 2325:TKV_RS01570
uniprot id: A0A097ANZ6
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

2325:TKV RS01125
gene id: 2325:TKV_RS01125
uniprot id: A0A097ANN2
names: Similarity
messages: Belongs to the UPF0749 family.

2325:TKV RS09165
gene id: 2325:TKV_RS09165
uniprot id: A0A097AT67
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 26 family. TagA/TarA subfamily.
messages: Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid.

2325:TKV RS00770
gene id: 2325:TKV_RS00770
uniprot id: A0A097ANG2
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

2325:TKV RS10895
gene id: 2325:TKV_RS10895
uniprot id: A0A097AU73
names: Subcellular Location Annotation
messages: Membrane

2325:TKV RS06360
gene id: 2325:TKV_RS06360
uniprot id: A0A097ARQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

2325:TKV RS06380
gene id: 2325:TKV_RS06380
uniprot id: A0A097ARQ4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

2325:TKV RS11450
gene id: 2325:TKV_RS11450
uniprot id: A0A097AUJ4
names: Similarity
messages: Belongs to the glycosyl hydrolase 130 family.

2325:TKV RS08395
gene id: 2325:TKV_RS08395
uniprot id: A0A097AST7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

2325:TKV RS01220
gene id: 2325:TKV_RS01220
uniprot id: A0A097ANS4
names: Similarity
messages: Belongs to the OsmC/Ohr family.

2325:TKV RS01410
gene id: 2325:TKV_RS01410
uniprot id: A0A097ANV2
names: Similarity
messages: Belongs to the CapA family.

2325:TKV RS03665
gene id: 2325:TKV_RS03665
uniprot id: A0A097AQ41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

2325:TKV RS00715
gene id: 2325:TKV_RS00715
uniprot id: A0A097ANF5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2325:TKV RS02640
gene id: 2325:TKV_RS02640
uniprot id: A0A097APJ0
names: Similarity
messages: Belongs to the MotB family.

2325:TKV RS00575
gene id: 2325:TKV_RS00575
uniprot id: A0A097ANC6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

2325:TKV RS11795
gene id: 2325:TKV_RS11795
uniprot id: A0A097AUR3
names: Similarity
messages: Belongs to the P(II) protein family.

2325:TKV RS02580
gene id: 2325:TKV_RS02580
uniprot id: A0A097APL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Membrane

2325:TKV RS03490
gene id: 2325:TKV_RS03490
uniprot id: A0A097AQ17
names: Subcellular Location Annotation
messages: Membrane

2325:TKV RS07720
gene id: 2325:TKV_RS07720
uniprot id: A0A097ASG2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

2325:TKV RS04905
gene id: 2325:TKV_RS04905
uniprot id: A0A097AQV2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

2325:TKV RS02390
gene id: 2325:TKV_RS02390
uniprot id: A0A097APE5
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

2325:TKV RS10030
gene id: 2325:TKV_RS10030
uniprot id: A0A097ATQ3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

2325:TKV RS02410
gene id: 2325:TKV_RS02410
uniprot id: A0A097APH4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum
messages: Belongs to the FliD family.
messages: Homopentamer.
messages: Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
messages: Secreted

2325:TKV RS04495
gene id: 2325:TKV_RS04495
uniprot id: A0A097AQP8
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

2325:TKV RS00875
gene id: 2325:TKV_RS00875
uniprot id: A0A097ANI4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Membrane

2325:TKV RS01715
gene id: 2325:TKV_RS01715
uniprot id: A0A097ANZ3
names: Subcellular Location Annotation
messages: Membrane

2325:TKV RS05405
gene id: 2325:TKV_RS05405
uniprot id: A0A097AR53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

2325:TKV RS10200
gene id: 2325:TKV_RS10200
uniprot id: A0A097ATS7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NRAMP family.
messages: Cell membrane
messages: H(+)-stimulated, divalent metal cation uptake system.

2325:TKV RS06725
gene id: 2325:TKV_RS06725
uniprot id: A0A097ARX5
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

2325:TKV RS03185
gene id: 2325:TKV_RS03185
uniprot id: A0A097APV6
names: Similarity
messages: Belongs to the UPF0175 family.

2325:TKV RS06515
gene id: 2325:TKV_RS06515
uniprot id: A0A097ARR3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

2325:TKV RS08090
gene id: 2325:TKV_RS08090
uniprot id: A0A097ASL1
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

2325:TKV RS08710
gene id: 2325:TKV_RS08710
uniprot id: A0A097AT22
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

2325:TKV RS00760
gene id: 2325:TKV_RS00760
uniprot id: A0A097ANG9
names: Similarity
messages: Belongs to the LacAB/RpiB family.

2325:TKV RS02860
gene id: 2325:TKV_RS02860
uniprot id: A0A097APN3
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

2325:TKV RS09265
gene id: 2325:TKV_RS09265
uniprot id: A0A097ATB9
names: Similarity
messages: Belongs to the UPF0047 family.

2325:TKV RS11465
gene id: 2325:TKV_RS11465
uniprot id: A0A097AUG8
names: Caution
names: Function
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the 2'-O methylation of guanosine at position 18 in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2325:TKV RS09740
gene id: 2325:TKV_RS09740
uniprot id: A0A097ATM1
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MobA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.
messages: Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.

2325:TKV RS06610
gene id: 2325:TKV_RS06610
uniprot id: A0A097ART5
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

2325:TKV RS00415
gene id: 2325:TKV_RS00415
uniprot id: A0A097AN96
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

2325:TKV RS06685
gene id: 2325:TKV_RS06685
uniprot id: A0A097ARU7
names: Function
names: Similarity
messages: Belongs to the UPF0122 family.
messages: Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein.

2325:TKV RS01060
gene id: 2325:TKV_RS01060
uniprot id: A0A097ANN0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. AddA subfamily.
messages: Heterodimer of AddA and AddB/RexB.
messages: The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation; this subunit has the helicase and 3' -> 5' nuclease activities.

2325:TKV RS07985
gene id: 2325:TKV_RS07985
uniprot id: A0A097ASJ8
names: Similarity
messages: Belongs to the Fur family.

2325:TKV RS00195
gene id: 2325:TKV_RS00195
uniprot id: A0A097AN61
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

2325:TKV RS05640
gene id: 2325:TKV_RS05640
uniprot id: A0A097AR98
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase MltG family.
messages: Cell membrane
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

2325:TKV RS07920
gene id: 2325:TKV_RS07920
uniprot id: A0A097ASH9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

2325:TKV RS09860
gene id: 2325:TKV_RS09860
uniprot id: A0A097ATM0
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

2325:TKV RS09800
gene id: 2325:TKV_RS09800
uniprot id: A0A097ATJ1
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

2325:TKV RS10415
gene id: 2325:TKV_RS10415
uniprot id: A0A097ATX6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

2325:TKV RS01880
gene id: 2325:TKV_RS01880
uniprot id: A0A097AP53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

2325:TKV RS01375
gene id: 2325:TKV_RS01375
uniprot id: A0A097ANU9
names: Subcellular Location Annotation
messages: Membrane

2325:TKV RS02175
gene id: 2325:TKV_RS02175
uniprot id: A0A097APC4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphopentomutase family.
messages: Binds 1 or 2 manganese ions.
messages: Cytoplasm
messages: Phosphotransfer between the C1 and C5 carbon atoms of pentose.

2325:TKV RS02515
gene id: 2325:TKV_RS02515
uniprot id: A0A097APG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

2325:TKV RS00105
gene id: 2325:TKV_RS00105
uniprot id: A0A097AN46
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

2325:TKV RS08560
gene id: 2325:TKV_RS08560
uniprot id: A0A097ASW9
names: Similarity
messages: Belongs to the universal stress protein A family.

2325:TKV RS01065
gene id: 2325:TKV_RS01065
uniprot id: A0A097ANP0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

2325:TKV RS06095
gene id: 2325:TKV_RS06095
uniprot id: A0A097ARK2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

2325:TKV RS11245
gene id: 2325:TKV_RS11245
uniprot id: A0A097AUF5
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

2325:TKV RS03240
gene id: 2325:TKV_RS03240
uniprot id: A0A097APV1
names: Subcellular Location Annotation
messages: Membrane

2325:TKV RS00250
gene id: 2325:TKV_RS00250
uniprot id: A0A097AN71
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane

2325:TKV RS01415
gene id: 2325:TKV_RS01415
uniprot id: A0A097ANW6
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

2325:TKV RS10145
gene id: 2325:TKV_RS10145
uniprot id: A0A097ATS1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

2325:TKV RS10235
gene id: 2325:TKV_RS10235
uniprot id: A0A097ATT8
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

2325:TKV RS02900
gene id: 2325:TKV_RS02900
uniprot id: A0A097APS3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

2325:TKV RS09080
gene id: 2325:TKV_RS09080
uniprot id: A0A097AT91
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.
messages: May be involved in the biosynthesis of molybdopterin.

2325:TKV RS00945
gene id: 2325:TKV_RS00945
uniprot id: A0A097ANL7
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

2325:TKV RS02380
gene id: 2325:TKV_RS02380
uniprot id: A0A097APE4
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

2325:TKV RS01545
gene id: 2325:TKV_RS01545
uniprot id: A0A097ANZ1
names: Function
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.

2325:TKV RS10095
gene id: 2325:TKV_RS10095
uniprot id: A0A097ATR2
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

2325:TKV RS06690
gene id: 2325:TKV_RS06690
uniprot id: A0A097ARU9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

2325:TKV RS07960
gene id: 2325:TKV_RS07960
uniprot id: A0A097ASJ5
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

2325:TKV RS06580
gene id: 2325:TKV_RS06580
uniprot id: A0A097ARU8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliF family.
messages: Membrane
messages: The M ring may be actively involved in energy transduction.

2325:TKV RS02325
gene id: 2325:TKV_RS02325
uniprot id: A0A097APD4
names: Function
names: Similarity
messages: Belongs to the RecD family. RecD-like subfamily.
messages: DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity.

2325:TKV RS05215
gene id: 2325:TKV_RS05215
uniprot id: A0A097AR36
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2325:TKV RS00985
gene id: 2325:TKV_RS00985
uniprot id: A0A097ANL2
names: Subcellular Location Annotation
messages: Membrane

2325:TKV RS04850
gene id: 2325:TKV_RS04850
uniprot id: A0A097AQU6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

2325:TKV RS02135
gene id: 2325:TKV_RS02135
uniprot id: A0A097APA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

2325:TKV RS08040
gene id: 2325:TKV_RS08040
uniprot id: A0A097ASK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

2325:TKV RS11640
gene id: 2325:TKV_RS11640
uniprot id: A0A097AUN2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Heptamer of 7 subunits arranged in a ring.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

2325:TKV RS03865
gene id: 2325:TKV_RS03865
uniprot id: A0A097AQ80
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

2325:TKV RS09460
gene id: 2325:TKV_RS09460
uniprot id: A0A097ATC1
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

2325:TKV RS00345
gene id: 2325:TKV_RS00345
uniprot id: A0A097AN84
names: Similarity
messages: Belongs to the glycosyl hydrolase 130 family.

2325:TKV RS07245
gene id: 2325:TKV_RS07245
uniprot id: A0A097AS73
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2325:TKV RS07495
gene id: 2325:TKV_RS07495
uniprot id: A0A097ASB3
names: Similarity
messages: Belongs to the UPF0749 family.

2325:TKV RS09895
gene id: 2325:TKV_RS09895
uniprot id: A0A097ATM3
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

2325:TKV RS08245
gene id: 2325:TKV_RS08245
uniprot id: A0A097ASQ6
names: Function
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The phosphoryl group from phosphoenolpyruvate (PEP) is transferred to the phosphoryl carrier protein HPr by enzyme I. Phospho-HPr then transfers it to the PTS EIIA domain.

2325:TKV RS07350
gene id: 2325:TKV_RS07350
uniprot id: A0A097AS74
names: Similarity
messages: Belongs to the FldB/FldC dehydratase alpha/beta subunit family.

2325:TKV RS02210
gene id: 2325:TKV_RS02210
uniprot id: A0A097APC1
names: Function
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.
messages: This protein is a Fe-Mo-cofactor biosynthetic component.

2325:TKV RS02705
gene id: 2325:TKV_RS02705
uniprot id: A0A097APN5
names: Similarity
messages: Belongs to the peptidase S8 family.

2325:TKV RS07730
gene id: 2325:TKV_RS07730
uniprot id: A0A097ASE9
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

2325:TKV RS01365
gene id: 2325:TKV_RS01365
uniprot id: A0A097ANV4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pseudouridine-5'-phosphate glycosidase family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the reversible cleavage of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway.
messages: Homotrimer.

2325:TKV RS04310
gene id: 2325:TKV_RS04310
uniprot id: A0A097AQH0
names: Similarity
messages: Belongs to the transglycosylase Slt family.

2325:TKV RS00050
gene id: 2325:TKV_RS00050
uniprot id: A0A097AN33
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

2325:TKV RS11705
gene id: 2325:TKV_RS11705
uniprot id: A0A097AUK9
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

2325:TKV RS09930
gene id: 2325:TKV_RS09930
uniprot id: A0A097ATK8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

2325:TKV RS08645
gene id: 2325:TKV_RS08645
uniprot id: A0A097ASZ0
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

2325:TKV RS03095
gene id: 2325:TKV_RS03095
uniprot id: A0A097APS2
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

2325:TKV RS11995
gene id: 2325:TKV_RS11995
uniprot id: A0A097AUV3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GdpP/PdeA phosphodiesterase family.
messages: Cell membrane
messages: For phosphodiesterase activity, probably binds 2 Mn(2+) per subunit.
messages: Has phosphodiesterase (PDE) activity against cyclic-di-AMP (c-di-AMP).

2325:TKV RS04375
gene id: 2325:TKV_RS04375
uniprot id: A0A097AQK6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2325:TKV RS11230
gene id: 2325:TKV_RS11230
uniprot id: A0A097AUC0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

2325:TKV RS02220
gene id: 2325:TKV_RS02220
uniprot id: A0A097APA6
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

2325:TKV RS06835
gene id: 2325:TKV_RS06835
uniprot id: A0A097ARX7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

2325:TKV RS05205
gene id: 2325:TKV_RS05205
uniprot id: A0A097AR04
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

2325:TKV RS06805
gene id: 2325:TKV_RS06805
uniprot id: A0A097ARZ2
names: Function
names: Similarity
messages: Belongs to the alpha/beta-type SASP family.
messages: SASP are bound to spore DNA. They are double-stranded DNA-binding proteins that cause DNA to change to an a-like conformation. They protect the DNA backbone from chemical and enzymatic cleavage and are thus involved in dormant spore's high resistance to UV light.

2325:TKV RS03415
gene id: 2325:TKV_RS03415
uniprot id: A0A097APY1
names: Similarity
messages: Belongs to the 4-oxalocrotonate tautomerase family.

2325:TKV RS06525
gene id: 2325:TKV_RS06525
uniprot id: A0A097ART6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

2325:TKV RS11430
gene id: 2325:TKV_RS11430
uniprot id: A0A097AUJ1
names: Similarity
messages: Belongs to the UPF0735 family.

2325:TKV RS00030
gene id: 2325:TKV_RS00030
uniprot id: A0A097AN30
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CobB/CobQ family. GatD subfamily.
messages: Forms a heterodimer with MurT.
messages: The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The GatD subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia. The resulting ammonia molecule is channeled to the active site of MurT.

2325:TKV RS08720
gene id: 2325:TKV_RS08720
uniprot id: A0A097AT10
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HPrK/P family.
messages: Both phosphorylation and phosphorolysis are carried out by the same active site and suggest a common mechanism for both reactions.
messages: Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr). The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK/P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport: it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion.
messages: Homohexamer.
messages: The Walker A ATP-binding motif also binds Pi and PPi.

2325:TKV RS03855
gene id: 2325:TKV_RS03855
uniprot id: A0A097AQC2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

2325:TKV RS10035
gene id: 2325:TKV_RS10035
uniprot id: A0A097ATP9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

2325:TKV RS07255
gene id: 2325:TKV_RS07255
uniprot id: A0A097AS54
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

2325:TKV RS03585
gene id: 2325:TKV_RS03585
uniprot id: A0A097AQ10
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2325:TKV RS09885
gene id: 2325:TKV_RS09885
uniprot id: A0A097ATM4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane
messages: Part of an ABC transporter complex. Responsible for energy coupling to the transport system.

2325:TKV RS01485
gene id: 2325:TKV_RS01485
uniprot id: A0A097ANX1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).

2325:TKV RS02595
gene id: 2325:TKV_RS02595
uniprot id: A0A097API0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

2325:TKV RS05460
gene id: 2325:TKV_RS05460
uniprot id: A0A097AR60
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

2325:TKV RS07575
gene id: 2325:TKV_RS07575
uniprot id: A0A097ASC4
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

2325:TKV RS05740
gene id: 2325:TKV_RS05740
uniprot id: A0A097ARB9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

2325:TKV RS02780
gene id: 2325:TKV_RS02780
uniprot id: A0A097APM2
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

2325:TKV RS00120
gene id: 2325:TKV_RS00120
uniprot id: A0A097AN47
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

2325:TKV RS02170
gene id: 2325:TKV_RS02170
uniprot id: A0A097AP96
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

2325:TKV RS11010
gene id: 2325:TKV_RS11010
uniprot id: A0A097AUA5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIIB subfamily.
messages: Cell inner membrane
messages: Mediates magnesium influx to the cytosol.

2325:TKV RS06140
gene id: 2325:TKV_RS06140
uniprot id: A0A097ARJ8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

2325:TKV RS01630
gene id: 2325:TKV_RS01630
uniprot id: A0A097AP03
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

2325:TKV RS10045
gene id: 2325:TKV_RS10045
uniprot id: A0A097ATQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

2325:TKV RS11250
gene id: 2325:TKV_RS11250
uniprot id: A0A097AUE8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

2325:TKV RS03475
gene id: 2325:TKV_RS03475
uniprot id: A0A097AQ02
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

2325:TKV RS03595
gene id: 2325:TKV_RS03595
uniprot id: A0A097AQ29
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2325:TKV RS09870
gene id: 2325:TKV_RS09870
uniprot id: A0A097ATL9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2325:TKV RS05200
gene id: 2325:TKV_RS05200
uniprot id: A0A097AR08
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

2325:TKV RS03155
gene id: 2325:TKV_RS03155
uniprot id: A0A097APU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

2325:TKV RS02675
gene id: 2325:TKV_RS02675
uniprot id: A0A097APN0
names: Cofactor
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.

2325:TKV RS00660
gene id: 2325:TKV_RS00660
uniprot id: A0A097ANG4
names: Similarity
messages: Belongs to the HupF/HypC family.

2325:TKV RS00420
gene id: 2325:TKV_RS00420
uniprot id: A0A097AN97
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2325:TKV RS11235
gene id: 2325:TKV_RS11235
uniprot id: A0A097AUE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1C family.
messages: Membrane

2325:TKV RS04600
gene id: 2325:TKV_RS04600
uniprot id: A0A097AQM5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

2325:TKV RS02940
gene id: 2325:TKV_RS02940
uniprot id: A0A097APR0
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

2325:TKV RS08805
gene id: 2325:TKV_RS08805
uniprot id: A0A097AT14
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

2325:TKV RS05125
gene id: 2325:TKV_RS05125
uniprot id: A0A097AQY9
names: Subcellular Location Annotation
messages: Membrane

2325:TKV RS04340
gene id: 2325:TKV_RS04340
uniprot id: A0A097AQH5
names: Similarity
messages: Belongs to the peptidase C40 family.

2325:TKV RS06500
gene id: 2325:TKV_RS06500
uniprot id: A0A097ARS7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

2325:TKV RS11845
gene id: 2325:TKV_RS11845
uniprot id: A0A097AUS3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

2325:TKV RS02865
gene id: 2325:TKV_RS02865
uniprot id: A0A097APP4
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2325:TKV RS01900
gene id: 2325:TKV_RS01900
uniprot id: A0A097ASQ9
names: Similarity
messages: Belongs to the UPF0236 family.

2325:TKV RS02930
gene id: 2325:TKV_RS02930
uniprot id: A0A097APQ8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

2325:TKV RS05555
gene id: 2325:TKV_RS05555
uniprot id: A0A097AR95
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2325:TKV RS02395
gene id: 2325:TKV_RS02395
uniprot id: A0A097APE7
names: Similarity
messages: Belongs to the asparagine synthetase family.

2325:TKV RS00860
gene id: 2325:TKV_RS00860
uniprot id: A0A097ANJ1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

2325:TKV RS08140
gene id: 2325:TKV_RS08140
uniprot id: A0A097ASR3
names: Similarity
messages: Belongs to the manganese catalase family.

2325:TKV RS06645
gene id: 2325:TKV_RS06645
uniprot id: A0A097ARV9
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

2325:TKV RS03170
gene id: 2325:TKV_RS03170
uniprot id: A0A097APT6
names: Subcellular Location Annotation
messages: Membrane

2325:TKV RS06435
gene id: 2325:TKV_RS06435
uniprot id: A0A097ARR7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

2325:TKV RS04480
gene id: 2325:TKV_RS04480
uniprot id: A0A097AQJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

2325:TKV RS06325
gene id: 2325:TKV_RS06325
uniprot id: A0A097ARP7
names: Similarity
messages: Belongs to the ribF family.

2325:TKV RS03260
gene id: 2325:TKV_RS03260
uniprot id: A0A097APW2
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

2325:TKV RS10440
gene id: 2325:TKV_RS10440
uniprot id: A0A097ATY9
names: Similarity
messages: Belongs to the EamA transporter family.

2325:TKV RS06270
gene id: 2325:TKV_RS06270
uniprot id: A0A097ARL0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
messages: Cytoplasm

2325:TKV RS02625
gene id: 2325:TKV_RS02625
uniprot id: A0A097APJ5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

2325:TKV RS05325
gene id: 2325:TKV_RS05325
uniprot id: A0A097AR33
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
messages: Synthesizes alpha-1,4-glucan chains using ADP-glucose.

2325:TKV RS12105
gene id: 2325:TKV_RS12105
uniprot id: A0A097AUT0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OXA1/ALB3/YidC family.
messages: Membrane

2325:TKV RS05870
gene id: 2325:TKV_RS05870
uniprot id: A0A097ARD0
names: Similarity
messages: Belongs to the TlyA family.

2325:TKV RS08885
gene id: 2325:TKV_RS08885
uniprot id: A0A097AT48
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated exonuclease Cas4 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).
messages: Mg(2+) or Mn(2+) required for ssDNA cleavage activity.

2325:TKV RS01550
gene id: 2325:TKV_RS01550
uniprot id: A0A097ANV8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobD/CbiB family.
messages: Cell membrane
messages: Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
messages: Membrane

2325:TKV RS08005
gene id: 2325:TKV_RS08005
uniprot id: A0A097ASN4
names: Similarity
messages: Belongs to the peptidase S16 family.

2325:TKV RS10005
gene id: 2325:TKV_RS10005
uniprot id: A0A097ATP8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

2325:TKV RS04275
gene id: 2325:TKV_RS04275
uniprot id: A0A097AQF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

2325:TKV RS04840
gene id: 2325:TKV_RS04840
uniprot id: A0A097AQU0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

2325:TKV RS04460
gene id: 2325:TKV_RS04460
uniprot id: A0A097AQM1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

2325:TKV RS04020
gene id: 2325:TKV_RS04020
uniprot id: A0A097AQC0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).

2325:TKV RS07610
gene id: 2325:TKV_RS07610
uniprot id: A0A097ASG3
names: Similarity
messages: Belongs to the desulfoferrodoxin family.

2325:TKV RS04705
gene id: 2325:TKV_RS04705
uniprot id: A0A097AQR9
names: Subcellular Location Annotation
messages: Membrane

2325:TKV RS07345
gene id: 2325:TKV_RS07345
uniprot id: A0A097AS72
names: Similarity
messages: Belongs to the FldB/FldC dehydratase alpha/beta subunit family.

2325:TKV RS02355
gene id: 2325:TKV_RS02355
uniprot id: A0A097APE0
names: Similarity
messages: Belongs to the bacterial flagellin family.

2325:TKV RS10020
gene id: 2325:TKV_RS10020
uniprot id: A0A097ATP7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

2325:TKV RS07900
gene id: 2325:TKV_RS07900
uniprot id: A0A097ASI1
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

2325:TKV RS11610
gene id: 2325:TKV_RS11610
uniprot id: A0A097AUJ2
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated protein Cas6/Cse3/CasE family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).

2325:TKV RS07550
gene id: 2325:TKV_RS07550
uniprot id: A0A097ASC1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

2325:TKV RS08790
gene id: 2325:TKV_RS08790
uniprot id: A0A097AT23
names: Similarity
messages: Belongs to the CdaR family.

2325:TKV RS11050
gene id: 2325:TKV_RS11050
uniprot id: A0A097AUB8
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

2325:TKV RS01460
gene id: 2325:TKV_RS01460
uniprot id: A0A097ANW2
names: Cofactor
messages: Binds 1 [2Fe-2S] cluster per subunit.

2325:TKV RS05210
gene id: 2325:TKV_RS05210
uniprot id: A0A097AR17
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M3B family.
messages: Binds 1 zinc ion.
messages: Has oligopeptidase activity and degrades a variety of small bioactive peptides.

2325:TKV RS10460
gene id: 2325:TKV_RS10460
uniprot id: A0A097ATY1
names: Subcellular Location Annotation
messages: Membrane

2325:TKV RS08160
gene id: 2325:TKV_RS08160
uniprot id: A0A097ASR8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2325:TKV RS07030
gene id: 2325:TKV_RS07030
uniprot id: A0A097AS15
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

2325:TKV RS02435
gene id: 2325:TKV_RS02435
uniprot id: A0A097APH9
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

2325:TKV RS04280
gene id: 2325:TKV_RS04280
uniprot id: A0A097AQI4
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

2325:TKV RS06665
gene id: 2325:TKV_RS06665
uniprot id: A0A097ARU4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein S19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein S19.

2325:TKV RS01340
gene id: 2325:TKV_RS01340
uniprot id: A0A097ANU8
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

2325:TKV RS05420
gene id: 2325:TKV_RS05420
uniprot id: A0A097AR61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

2325:TKV RS02845
gene id: 2325:TKV_RS02845
uniprot id: A0A097APN6
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane.

2325:TKV RS07515
gene id: 2325:TKV_RS07515
uniprot id: A0A097ASB1
names: Subcellular Location Annotation
messages: Membrane

2325:TKV RS06255
gene id: 2325:TKV_RS06255
uniprot id: A0A097ARM8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

2325:TKV RS03510
gene id: 2325:TKV_RS03510
uniprot id: A0A097AQ15
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

2325:TKV RS02500
gene id: 2325:TKV_RS02500
uniprot id: A0A097APG8
names: Similarity
messages: Belongs to the Mg-chelatase subunit H family.

2325:TKV RS11630
gene id: 2325:TKV_RS11630
uniprot id: A0A097AUN0
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

2325:TKV RS02820
gene id: 2325:TKV_RS02820
uniprot id: A0A097APN1
names: Subcellular Location Annotation
messages: Membrane

2325:TKV RS06695
gene id: 2325:TKV_RS06695
uniprot id: A0A097ARW8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

2325:TKV RS04050
gene id: 2325:TKV_RS04050
uniprot id: A0A097AQE8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S8 family.
messages: Monomer.
messages: Serine protease with a broad substrate specificity.

2325:TKV RS01435
gene id: 2325:TKV_RS01435
uniprot id: A0A097ANV7
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

2325:TKV RS07750
gene id: 2325:TKV_RS07750
uniprot id: A0A097ASF6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

2325:TKV RS06775
gene id: 2325:TKV_RS06775
uniprot id: A0A097ARY5
names: Similarity
messages: Belongs to the phosphate acetyltransferase and butyryltransferase family.

2325:TKV RS02745
gene id: 2325:TKV_RS02745
uniprot id: A0A097APL5
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

2325:TKV RS09865
gene id: 2325:TKV_RS09865
uniprot id: A0A097ATL4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

2325:TKV RS06605
gene id: 2325:TKV_RS06605
uniprot id: A0A097ARV2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
messages: Belongs to the ClpX chaperone family. HslU subfamily.
messages: Cytoplasm

2325:TKV RS04380
gene id: 2325:TKV_RS04380
uniprot id: A0A097AQH6
names: Function
names: Similarity
messages: Belongs to the MreC family.
messages: Involved in formation and maintenance of cell shape.

2325:TKV RS08740
gene id: 2325:TKV_RS08740
uniprot id: A0A097AT12
names: Subcellular Location Annotation
messages: Membrane

2325:TKV RS07005
gene id: 2325:TKV_RS07005
uniprot id: A0A097AS09
names: Similarity
messages: Belongs to the OMP decarboxylase family. Type 2 subfamily.

2325:TKV RS01540
gene id: 2325:TKV_RS01540
uniprot id: A0A097ANX4
names: Domain
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the CobB/CbiA family.
messages: Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source.
messages: Comprises of two domains. The C-terminal domain contains the binding site for glutamine and catalyzes the hydrolysis of this substrate to glutamate and ammonia. The N-terminal domain is anticipated to bind ATP and cobyrinate and catalyzes the ultimate synthesis of the diamide product. The ammonia produced via the glutaminase domain is probably translocated to the adjacent domain via a molecular tunnel, where it reacts with an activated intermediate.
messages: The a and c carboxylates of cobyrinate are activated for nucleophilic attack via formation of a phosphorylated intermediate by ATP. CbiA catalyzes first the amidation of the c-carboxylate, and then that of the a-carboxylate.

2325:TKV RS00685
gene id: 2325:TKV_RS00685
uniprot id: A0A097ANG7
names: Similarity
messages: Belongs to the HupF/HypC family.

2325:TKV RS04230
gene id: 2325:TKV_RS04230
uniprot id: A0A097AQF6
names: Similarity
messages: Belongs to the UPF0340 family.

2325:TKV RS06715
gene id: 2325:TKV_RS06715
uniprot id: A0A097ARV4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

2325:TKV RS00070
gene id: 2325:TKV_RS00070
uniprot id: A0A097AN38
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2325:TKV RS06060
gene id: 2325:TKV_RS06060
uniprot id: A0A097ARI5
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

2325:TKV RS06430
gene id: 2325:TKV_RS06430
uniprot id: A0A097ARR5
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2325:TKV RS00460
gene id: 2325:TKV_RS00460
uniprot id: A0A097ANC3
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

2325:TKV RS09585
gene id: 2325:TKV_RS09585
uniprot id: A0A097ATH3
names: Subcellular Location Annotation
messages: Membrane

2325:TKV RS11220
gene id: 2325:TKV_RS11220
uniprot id: A0A097AUF0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

2325:TKV RS06150
gene id: 2325:TKV_RS06150
uniprot id: A0A097ARL3
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
messages: Heterotetramer of two alpha and two beta chains arranged as a dimer of alpha/beta heterodimers.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl group blocking the N-terminus of the alpha chain.

2325:TKV RS06675
gene id: 2325:TKV_RS06675
uniprot id: A0A097ARW6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

2325:TKV RS00390
gene id: 2325:TKV_RS00390
uniprot id: A0A097ANB4
names: Similarity
messages: Belongs to the class-I fumarase family.

2325:TKV RS08915
gene id: 2325:TKV_RS08915
uniprot id: A0A097AT43
names: Similarity
messages: Belongs to the phosphohexose mutase family.

2325:TKV RS01035
gene id: 2325:TKV_RS01035
uniprot id: A0A097ANM5
names: Similarity
messages: Belongs to the hemerythrin family.

2325:TKV RS07230
gene id: 2325:TKV_RS07230
uniprot id: A0A097AS50
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

2325:TKV RS11520
gene id: 2325:TKV_RS11520
uniprot id: A0A097AUK8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

2325:TKV RS02875
gene id: 2325:TKV_RS02875
uniprot id: A0A097APR8
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

2325:TKV RS04130
gene id: 2325:TKV_RS04130
uniprot id: A0A097AQD1
names: Similarity
messages: Belongs to the glutamine synthetase family.

2325:TKV RS03270
gene id: 2325:TKV_RS03270
uniprot id: A0A097APX1
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

2325:TKV RS11990
gene id: 2325:TKV_RS11990
uniprot id: A0A097AUQ2
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

2325:TKV RS04630
gene id: 2325:TKV_RS04630
uniprot id: A0A097AQN0
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

2325:TKV RS06020
gene id: 2325:TKV_RS06020
uniprot id: A0A097ARI7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ScpB family.
messages: Cytoplasm
messages: Homodimer. Homodimerization may be required to stabilize the binding of ScpA to the Smc head domains. Component of a cohesin-like complex composed of ScpA, ScpB and the Smc homodimer, in which ScpA and ScpB bind to the head domain of Smc. The presence of the three proteins is required for the association of the complex with DNA.
messages: Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves.

2325:TKV RS06340
gene id: 2325:TKV_RS06340
uniprot id: A0A097ARN4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

2325:TKV RS08900
gene id: 2325:TKV_RS08900
uniprot id: A0A097AT56
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpC family.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

2325:TKV RS00330
gene id: 2325:TKV_RS00330
uniprot id: A0A097AN77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

2325:TKV RS11350
gene id: 2325:TKV_RS11350
uniprot id: A0A097AUH6
names: Activity Regulation
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.

2325:TKV RS09710
gene id: 2325:TKV_RS09710
uniprot id: A0A097ATK0
names: Subcellular Location Annotation
messages: Membrane

2325:TKV RS02180
gene id: 2325:TKV_RS02180
uniprot id: A0A097AP88
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
messages: Catalyzes phosphorolysis of the pyrimidine nucleosides uridine, thymidine and 2'-deoxyuridine with the formation of the corresponding pyrimidine base and ribose-1-phosphate.
messages: Homodimer.

2325:TKV RS04635
gene id: 2325:TKV_RS04635
uniprot id: A0A097AQQ5
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

2325:TKV RS11475
gene id: 2325:TKV_RS11475
uniprot id: A0A097AUK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CRISPR system Cmr5 family.
messages: Cytoplasm

2325:TKV RS11525
gene id: 2325:TKV_RS11525
uniprot id: A0A097AUH8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

2325:TKV RS02605
gene id: 2325:TKV_RS02605
uniprot id: A0A097API6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic riboflavin transporter (P-RFT) (TC 2.A.87) family.
messages: Cell membrane
messages: Membrane
messages: Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex.

2325:TKV RS05115
gene id: 2325:TKV_RS05115
uniprot id: A0A097AR18
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

2325:TKV RS06850
gene id: 2325:TKV_RS06850
uniprot id: A0A097ARZ8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

2325:TKV RS06890
gene id: 2325:TKV_RS06890
uniprot id: A0A097ARZ1
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

2325:TKV RS11975
gene id: 2325:TKV_RS11975
uniprot id: A0A097AUQ5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HCP family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Binds 1 hybrid [4Fe-2O-2S] cluster.
messages: Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
messages: Cytoplasm

2325:TKV RS09210
gene id: 2325:TKV_RS09210
uniprot id: A0A097ATB8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Belongs to the P-Pant transferase superfamily. Gsp/Sfp/HetI/AcpT family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

2325:TKV RS07370
gene id: 2325:TKV_RS07370
uniprot id: A0A097AS89
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell membrane
messages: Probably interacts with PlsX.

2325:TKV RS09995
gene id: 2325:TKV_RS09995
uniprot id: A0A097ATN9
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

2325:TKV RS05695
gene id: 2325:TKV_RS05695
uniprot id: A0A097AR96
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A24 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Plays an essential role in type IV pili and type II pseudopili formation by proteolytically removing the leader sequence from substrate proteins and subsequently monomethylating the alpha-amino group of the newly exposed N-terminal phenylalanine.

2325:TKV RS11305
gene id: 2325:TKV_RS11305
uniprot id: A0A097AUD4
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.

2325:TKV RS10010
gene id: 2325:TKV_RS10010
uniprot id: A0A097ATP5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

2325:TKV RS10870
gene id: 2325:TKV_RS10870
uniprot id: A0A097AU68
names: Cofactor
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.

2325:TKV RS11835
gene id: 2325:TKV_RS11835
uniprot id: A0A097AUS2
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

2325:TKV RS08715
gene id: 2325:TKV_RS08715
uniprot id: A0A097AT06
names: Cofactor
names: Similarity
messages: Belongs to the PHP family.
messages: Binds 3 Zn(2+) ions per subunit.

2325:TKV RS01170
gene id: 2325:TKV_RS01170
uniprot id: A0A097ANR1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-insensitive subfamily.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force.

2325:TKV RS06300
gene id: 2325:TKV_RS06300
uniprot id: A0A097ARP2
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

2325:TKV RS04755
gene id: 2325:TKV_RS04755
uniprot id: A0A097AQS5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

2325:TKV RS08845
gene id: 2325:TKV_RS08845
uniprot id: A0A097AT32
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

2325:TKV RS00325
gene id: 2325:TKV_RS00325
uniprot id: A0A097AN81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

2325:TKV RS08445
gene id: 2325:TKV_RS08445
uniprot id: A0A097ASU8
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated Csm2 family.
messages: This subunit may be involved in monitoring complementarity of crRNA and target RNA.

2325:TKV RS11420
gene id: 2325:TKV_RS11420
uniprot id: A0A097AUI8
names: Function
names: Similarity
messages: Belongs to the threonine synthase family.
messages: Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.

2325:TKV RS11665
gene id: 2325:TKV_RS11665
uniprot id: A0A097AUN8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

2325:TKV RS03010
gene id: 2325:TKV_RS03010
uniprot id: A0A097APR5
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

2325:TKV RS11680
gene id: 2325:TKV_RS11680
uniprot id: A0A097AUK4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2325:TKV RS02800
gene id: 2325:TKV_RS02800
uniprot id: A0A097APQ4
names: Similarity
messages: Belongs to the GARS family.

2325:TKV RS07925
gene id: 2325:TKV_RS07925
uniprot id: A0A097ASI0
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

2325:TKV RS06495
gene id: 2325:TKV_RS06495
uniprot id: A0A097ARQ7
names: Function
names: Similarity
messages: Belongs to the GTP-binding SRP family.
messages: Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum.

2325:TKV RS11185
gene id: 2325:TKV_RS11185
uniprot id: A0A097AUD8
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

2325:TKV RS04105
gene id: 2325:TKV_RS04105
uniprot id: A0A097AQC6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

2325:TKV RS08285
gene id: 2325:TKV_RS08285
uniprot id: A0A097ASQ9
names: Similarity
messages: Belongs to the UPF0236 family.

2325:TKV RS10880
gene id: 2325:TKV_RS10880
uniprot id: A0A097AU72
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus
messages: Repair polymerase that plays a key role in base-excision repair. Has 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity that removes the 5' sugar phosphate and also acts as a DNA polymerase that adds one nucleotide to the 3' end of the arising single-nucleotide gap. Conducts 'gap-filling' DNA synthesis in a stepwise distributive fashion rather than in a processive fashion as for other DNA polymerases.

2325:TKV RS09970
gene id: 2325:TKV_RS09970
uniprot id: A0A097ATN5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

2325:TKV RS08970
gene id: 2325:TKV_RS08970
uniprot id: A0A097AT68
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

2325:TKV RS02065
gene id: 2325:TKV_RS02065
uniprot id: A0A097AP76
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

2325:TKV RS02700
gene id: 2325:TKV_RS02700
uniprot id: A0A097APK6
names: Function
names: Similarity
names: Subunit
messages: Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization.
messages: Belongs to the HutP family.
messages: Homohexamer.

2325:TKV RS10115
gene id: 2325:TKV_RS10115
uniprot id: A0A097ATQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

2325:TKV RS07975
gene id: 2325:TKV_RS07975
uniprot id: A0A097ASJ0
names: Similarity
messages: Belongs to the acylphosphatase family.

2325:TKV RS11130
gene id: 2325:TKV_RS11130
uniprot id: A0A097AUC6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

2325:TKV RS09160
gene id: 2325:TKV_RS09160
uniprot id: A0A097ATA7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

2325:TKV RS09760
gene id: 2325:TKV_RS09760
uniprot id: A0A097ATL1
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

2325:TKV RS00310
gene id: 2325:TKV_RS00310
uniprot id: A0A097AN99
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

2325:TKV RS01010
gene id: 2325:TKV_RS01010
uniprot id: A0A097ANL9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

2325:TKV RS04395
gene id: 2325:TKV_RS04395
uniprot id: A0A097AQM6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MinC family.
messages: Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization.
messages: Interacts with MinD and FtsZ.

2325:TKV RS10365
gene id: 2325:TKV_RS10365
uniprot id: A0A097ATW4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

2325:TKV RS09680
gene id: 2325:TKV_RS09680
uniprot id: A0A097ATJ3
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

2325:TKV RS00850
gene id: 2325:TKV_RS00850
uniprot id: A0A097ANI0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2325:TKV RS06320
gene id: 2325:TKV_RS06320
uniprot id: A0A097ARM1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

2325:TKV RS10015
gene id: 2325:TKV_RS10015
uniprot id: A0A097ATP6
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

2325:TKV RS05755
gene id: 2325:TKV_RS05755
uniprot id: A0A097ARC8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

2325:TKV RS01190
gene id: 2325:TKV_RS01190
uniprot id: A0A097ANR4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

2325:TKV RS00235
gene id: 2325:TKV_RS00235
uniprot id: A0A097AN91
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

2325:TKV RS05960
gene id: 2325:TKV_RS05960
uniprot id: A0A097ARG9
names: Function
names: Similarity
messages: Belongs to the 'phage' integrase family.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.

2325:TKV RS11780
gene id: 2325:TKV_RS11780
uniprot id: A0A097AUL7
names: Similarity
messages: Belongs to the glutamate synthase family.

2325:TKV RS07330
gene id: 2325:TKV_RS07330
uniprot id: A0A097AS85
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

2325:TKV RS08950
gene id: 2325:TKV_RS08950
uniprot id: A0A097AT59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

2325:TKV RS06820
gene id: 2325:TKV_RS06820
uniprot id: A0A097ARZ5
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

2325:TKV RS11560
gene id: 2325:TKV_RS11560
uniprot id: A0A097AUL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CRISPR system Cmr5 family.
messages: Cytoplasm

2325:TKV RS10265
gene id: 2325:TKV_RS10265
uniprot id: A0A097ATV4
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

2325:TKV RS01085
gene id: 2325:TKV_RS01085
uniprot id: A0A097ANN7
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Belongs to the peroxiredoxin family. Prx6 subfamily.
messages: Cytoplasm
messages: Homodecamer. Pentamer of dimers that assemble into a ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. In this 1-Cys peroxiredoxin, no C(R) is present and C(P) instead forms a disulfide with a cysteine from another protein or with a small thiol molecule.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

2325:TKV RS00100
gene id: 2325:TKV_RS00100
uniprot id: A0A097AN42
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

2325:TKV RS09495
gene id: 2325:TKV_RS09495
uniprot id: A0A097ATC9
names: Similarity
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Spore germination protein (SGP) (TC 2.A.3.9) family.

2325:TKV RS09880
gene id: 2325:TKV_RS09880
uniprot id: A0A097ATJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex.
messages: Belongs to the ABC transporter superfamily. Energy-coupling factor EcfA family.
messages: Cell membrane
messages: Forms a stable energy-coupling factor (ECF) transporter complex composed of 2 membrane-embedded substrate-binding proteins (S component), 2 ATP-binding proteins (A component) and 2 transmembrane proteins (T component).
messages: Membrane

2325:TKV RS04300
gene id: 2325:TKV_RS04300
uniprot id: A0A097AQG1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
messages: Single-chain monomer with multiple functions.

2325:TKV RS06545
gene id: 2325:TKV_RS06545
uniprot id: A0A097ART8
names: Similarity
messages: Belongs to the FlgD family.

2325:TKV RS01330
gene id: 2325:TKV_RS01330
uniprot id: A0A097ANU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0014 family.
messages: Membrane

2325:TKV RS01670
gene id: 2325:TKV_RS01670
uniprot id: A0A097ANY3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CbiN family.
messages: Cell membrane
messages: Forms an energy-coupling factor (ECF) transporter complex composed of an ATP-binding protein (A component, CbiO), a transmembrane protein (T component, CbiQ) and 2 possible substrate-capture proteins (S components, CbiM and CbiN) of unknown stoichimetry.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import.

2325:TKV RS00005
gene id: 2325:TKV_RS00005
uniprot id: A0A097AN25
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

2325:TKV RS05590
gene id: 2325:TKV_RS05590
uniprot id: A0A097AR89
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2325:TKV RS10170
gene id: 2325:TKV_RS10170
uniprot id: A0A097ATS5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2325:TKV RS02805
gene id: 2325:TKV_RS02805
uniprot id: A0A097APM7
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

2325:TKV RS06195
gene id: 2325:TKV_RS06195
uniprot id: A0A097ARJ5
names: Function
names: Similarity
messages: Belongs to the 'phage' integrase family.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.

2325:TKV RS07015
gene id: 2325:TKV_RS07015
uniprot id: A0A097AS30
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

2325:TKV RS01635
gene id: 2325:TKV_RS01635
uniprot id: A0A097ANZ4
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

2325:TKV RS08130
gene id: 2325:TKV_RS08130
uniprot id: A0A097ASN5
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

2325:TKV RS01440
gene id: 2325:TKV_RS01440
uniprot id: A0A097ANX2
names: Similarity
messages: Belongs to the Fur family.

2325:TKV RS04725
gene id: 2325:TKV_RS04725
uniprot id: A0A097AQQ0
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Autoproteolytically processed. The inactive tetrameric zymogen termed p46 autoprocesses to a smaller form termed p41, which is active only during spore germination.
messages: Belongs to the peptidase A25 family.
messages: Homotetramer.
messages: Initiates the rapid degradation of small, acid-soluble proteins during spore germination.

2325:TKV RS08325
gene id: 2325:TKV_RS08325
uniprot id: A0A097ASS4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

2325:TKV RS02415
gene id: 2325:TKV_RS02415
uniprot id: A0A097APF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliS family.
messages: cytosol

2325:TKV RS02450
gene id: 2325:TKV_RS02450
uniprot id: A0A097APG0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

2325:TKV RS10080
gene id: 2325:TKV_RS10080
uniprot id: A0A097ATR7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

2325:TKV RS07825
gene id: 2325:TKV_RS07825
uniprot id: A0A097ASG4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sirtuin family. Class U subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form.

2325:TKV RS06615
gene id: 2325:TKV_RS06615
uniprot id: A0A097ART4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

2325:TKV RS02670
gene id: 2325:TKV_RS02670
uniprot id: A0A097APK1
names: Similarity
messages: Belongs to the asp23 family.

2325:TKV RS08450
gene id: 2325:TKV_RS08450
uniprot id: A0A097ASV1
names: Similarity
messages: Belongs to the CRISPR-associated Cas10/Csm1 family.

2325:TKV RS05085
gene id: 2325:TKV_RS05085
uniprot id: A0A097AQZ1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

2325:TKV RS06260
gene id: 2325:TKV_RS06260
uniprot id: A0A097ARN0
names: Similarity
messages: Belongs to the CinA family.

2325:TKV RS06630
gene id: 2325:TKV_RS06630
uniprot id: A0A097ARV8
names: Similarity
messages: Belongs to the UPF0102 family.

2325:TKV RS06415
gene id: 2325:TKV_RS06415
uniprot id: A0A097ARP6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

2325:TKV RS01405
gene id: 2325:TKV_RS01405
uniprot id: A0A097ANV6
names: Similarity
messages: Belongs to the mannitol dehydrogenase family.

2325:TKV RS00085
gene id: 2325:TKV_RS00085
uniprot id: A0A097AN40
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 2 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

2325:TKV RS02060
gene id: 2325:TKV_RS02060
uniprot id: A0A097AP92
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

2325:TKV RS01685
gene id: 2325:TKV_RS01685
uniprot id: A0A097AP04
names: Similarity
messages: Belongs to the band 7/mec-2 family.

2325:TKV RS00680
gene id: 2325:TKV_RS00680
uniprot id: A0A097ANE5
names: Similarity
messages: Belongs to the acylphosphatase family.
messages: Belongs to the carbamoyltransferase HypF family.

2325:TKV RS01100
gene id: 2325:TKV_RS01100
uniprot id: A0A097ANM7
names: Cofactor
names: Similarity
messages: Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.
messages: Binds 1 zinc ion per subunit.

2325:TKV RS04845
gene id: 2325:TKV_RS04845
uniprot id: A0A097AQU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Membrane

2325:TKV RS09705
gene id: 2325:TKV_RS09705
uniprot id: A0A097ATJ5
names: Similarity
messages: Belongs to the formate--tetrahydrofolate ligase family.

2325:TKV RS06425
gene id: 2325:TKV_RS06425
uniprot id: A0A097ARR6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

2325:TKV RS08305
gene id: 2325:TKV_RS08305
uniprot id: A0A097ASQ3
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

2325:TKV RS05630
gene id: 2325:TKV_RS05630
uniprot id: A0A097ARA7
names: Similarity
messages: Belongs to the UPF0342 family.

2325:TKV RS02240
gene id: 2325:TKV_RS02240
uniprot id: A0A097APC6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM61 family.
messages: Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA.
messages: Homotetramer composed of a dimer of dimers.

2325:TKV RS05275
gene id: 2325:TKV_RS05275
uniprot id: A0A097AR25
names: Similarity
messages: Belongs to the thioredoxin family.

2325:TKV RS06930
gene id: 2325:TKV_RS06930
uniprot id: A0A097AS13
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2325:TKV RS05880
gene id: 2325:TKV_RS05880
uniprot id: A0A097ARF2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

2325:TKV RS09780
gene id: 2325:TKV_RS09780
uniprot id: A0A097ATL6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

2325:TKV RS08225
gene id: 2325:TKV_RS08225
uniprot id: A0A097ASQ5
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2325:TKV RS02425
gene id: 2325:TKV_RS02425
uniprot id: A0A097APF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

2325:TKV RS07590
gene id: 2325:TKV_RS07590
uniprot id: A0A097ASC3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThiI family.
messages: Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
messages: Cytoplasm

2325:TKV RS08905
gene id: 2325:TKV_RS08905
uniprot id: A0A097AT47
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system and for the release of the potassium ions to the cytoplasm.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

2325:TKV RS09985
gene id: 2325:TKV_RS09985
uniprot id: A0A097ATP0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

2325:TKV RS07965
gene id: 2325:TKV_RS07965
uniprot id: A0A097ASK5
names: Similarity
messages: Belongs to the SorC transcriptional regulatory family.

2325:TKV RS07745
gene id: 2325:TKV_RS07745
uniprot id: A0A097ASG8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

2325:TKV RS06635
gene id: 2325:TKV_RS06635
uniprot id: A0A097ART9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.

2325:TKV RS02225
gene id: 2325:TKV_RS02225
uniprot id: A0A097APD0
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

2325:TKV RS06305
gene id: 2325:TKV_RS06305
uniprot id: A0A097ARN9
names: Similarity
messages: Belongs to the peptidase M16 family.

2325:TKV RS04260
gene id: 2325:TKV_RS04260
uniprot id: A0A097AQG0
names: Subcellular Location Annotation
messages: Membrane

2325:TKV RS07660
gene id: 2325:TKV_RS07660
uniprot id: A0A097ASH2
names: Similarity
messages: Belongs to the peptidase M18 family.

2325:TKV RS01785
gene id: 2325:TKV_RS01785
uniprot id: A0A097AP21
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

2325:TKV RS08385
gene id: 2325:TKV_RS08385
uniprot id: A0A097ASR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

2325:TKV RS08155
gene id: 2325:TKV_RS08155
uniprot id: A0A097ASN0
names: Function
names: Similarity
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

2325:TKV RS10000
gene id: 2325:TKV_RS10000
uniprot id: A0A097ATP4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

2325:TKV RS10100
gene id: 2325:TKV_RS10100
uniprot id: A0A097ATR5
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

2325:TKV RS01370
gene id: 2325:TKV_RS01370
uniprot id: A0A097ANS6
names: Similarity
messages: Belongs to the Tlp family.

2325:TKV RS02115
gene id: 2325:TKV_RS02115
uniprot id: A0A097APA2
names: Cofactor
names: Similarity
messages: Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.
messages: Binds 3 [4Fe-4S] clusters per subunit.

2325:TKV RS00765
gene id: 2325:TKV_RS00765
uniprot id: A0A097ANG6
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

2325:TKV RS02600
gene id: 2325:TKV_RS02600
uniprot id: A0A097API8
names: Similarity
messages: Belongs to the carbamate kinase family.

2325:TKV RS06400
gene id: 2325:TKV_RS06400
uniprot id: A0A097ARR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

2325:TKV RS09065
gene id: 2325:TKV_RS09065
uniprot id: A0A097AT77
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

2325:TKV RS11805
gene id: 2325:TKV_RS11805
uniprot id: A0A097AUM0
names: Similarity
messages: Belongs to the glutamine synthetase family.

2325:TKV RS11345
gene id: 2325:TKV_RS11345
uniprot id: A0A097AUE6
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

2325:TKV RS02725
gene id: 2325:TKV_RS02725
uniprot id: A0A097APL2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

2325:TKV RS10245
gene id: 2325:TKV_RS10245
uniprot id: A0A097ATU1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

2325:TKV RS07715
gene id: 2325:TKV_RS07715
uniprot id: A0A097ASF1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

2325:TKV RS05020
gene id: 2325:TKV_RS05020
uniprot id: A0A097AQX7
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

2325:TKV RS01350
gene id: 2325:TKV_RS01350
uniprot id: A0A097ANU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

2325:TKV RS08235
gene id: 2325:TKV_RS08235
uniprot id: A0A097ASP7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-C family. DnaE subfamily.
messages: Cytoplasm
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The alpha chain is the DNA polymerase.

2325:TKV RS03080
gene id: 2325:TKV_RS03080
uniprot id: A0A097APS9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

2325:TKV RS10075
gene id: 2325:TKV_RS10075
uniprot id: A0A097ATQ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

2325:TKV RS09510
gene id: 2325:TKV_RS09510
uniprot id: A0A097ATF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

2325:TKV RS01930
gene id: 2325:TKV_RS01930
uniprot id: A0A097AP75
names: Similarity
messages: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family.

2325:TKV RS06920
gene id: 2325:TKV_RS06920
uniprot id: A0A097ARZ6
names: Similarity
messages: Belongs to the RemA family.

2325:TKV RS04290
gene id: 2325:TKV_RS04290
uniprot id: A0A097AQK7
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

2325:TKV RS09915
gene id: 2325:TKV_RS09915
uniprot id: A0A097ATM2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

2325:TKV RS08150
gene id: 2325:TKV_RS08150
uniprot id: A0A097ASP0
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.

2325:TKV RS06045
gene id: 2325:TKV_RS06045
uniprot id: A0A097ARJ2
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

2325:TKV RS09090
gene id: 2325:TKV_RS09090
uniprot id: A0A097AT80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane

2325:TKV RS04875
gene id: 2325:TKV_RS04875
uniprot id: A0A097AQU9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of glycine to tRNA(Gly).
messages: Cytoplasm
messages: Homodimer.

2325:TKV RS02610
gene id: 2325:TKV_RS02610
uniprot id: A0A097APL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

2325:TKV RS03135
gene id: 2325:TKV_RS03135
uniprot id: A0A097APW5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

2325:TKV RS09405
gene id: 2325:TKV_RS09405
uniprot id: A0A097ATB1
names: Similarity
messages: Belongs to the phosphate acetyltransferase and butyryltransferase family.

2325:TKV RS00530
gene id: 2325:TKV_RS00530
uniprot id: A0A097ANB5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

2325:TKV RS05850
gene id: 2325:TKV_RS05850
uniprot id: A0A097ARF0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

2325:TKV RS02730
gene id: 2325:TKV_RS02730
uniprot id: A0A097APK9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

2325:TKV RS03030
gene id: 2325:TKV_RS03030
uniprot id: A0A097APU2
names: Similarity
messages: Belongs to the leucine-binding protein family.

2325:TKV RS00735
gene id: 2325:TKV_RS00735
uniprot id: A0A097ANG3
names: Caution
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

2325:TKV RS06590
gene id: 2325:TKV_RS06590
uniprot id: A0A097ART0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

2325:TKV RS06995
gene id: 2325:TKV_RS06995
uniprot id: A0A097AS23
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate.
messages: Cytoplasm

2325:TKV RS02160
gene id: 2325:TKV_RS02160
uniprot id: A0A097APB2
names: Subcellular Location Annotation
messages: Membrane

2325:TKV RS02535
gene id: 2325:TKV_RS02535
uniprot id: A0A097APH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

2325:TKV RS00855
gene id: 2325:TKV_RS00855
uniprot id: A0A097ANJ9
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

2325:TKV RS00450
gene id: 2325:TKV_RS00450
uniprot id: A0A097ANA2
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

2325:TKV RS00795
gene id: 2325:TKV_RS00795
uniprot id: A0A097ANG8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2325:TKV RS02815
gene id: 2325:TKV_RS02815
uniprot id: A0A097APN4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LuxS family.
messages: Binds 1 Fe cation per subunit.
messages: Homodimer.
messages: Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).

2325:TKV RS04345
gene id: 2325:TKV_RS04345
uniprot id: A0A097AQL8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

2325:TKV RS10705
gene id: 2325:TKV_RS10705
uniprot id: A0A097AU34
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

2325:TKV RS04770
gene id: 2325:TKV_RS04770
uniprot id: A0A097AQS9
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

2325:TKV RS07235
gene id: 2325:TKV_RS07235
uniprot id: A0A097AS71
names: Similarity
messages: Belongs to the TrpF family.

2325:TKV RS09980
gene id: 2325:TKV_RS09980
uniprot id: A0A097ATP3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

2325:TKV RS06560
gene id: 2325:TKV_RS06560
uniprot id: A0A097ARS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliJ family.
messages: Cell membrane
messages: Membrane

2325:TKV RS06180
gene id: 2325:TKV_RS06180
uniprot id: A0A097ARL1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

2325:TKV RS09715
gene id: 2325:TKV_RS09715
uniprot id: A0A097ATL7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhD family.
messages: Cytoplasm
messages: Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.

2325:TKV RS02685
gene id: 2325:TKV_RS02685
uniprot id: A0A097APK2
names: Similarity
messages: Belongs to the glutamate synthase family.

2325:TKV RS01020
gene id: 2325:TKV_RS01020
uniprot id: A0A097ANM9
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

2325:TKV RS11145
gene id: 2325:TKV_RS11145
uniprot id: A0A097AUC7
names: Similarity
messages: Belongs to the SleB family.

2325:TKV RS09345
gene id: 2325:TKV_RS09345
uniprot id: A0A097ATD1
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

2325:TKV RS02850
gene id: 2325:TKV_RS02850
uniprot id: A0A097APR4
names: Cofactor
messages: Binds 1 Mg(2+) ion per trimer.

2325:TKV RS04750
gene id: 2325:TKV_RS04750
uniprot id: A0A097AQQ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

2325:TKV RS10180
gene id: 2325:TKV_RS10180
uniprot id: A0A097ATS6
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

2325:TKV RS07340
gene id: 2325:TKV_RS07340
uniprot id: A0A097AS86
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

2325:TKV RS09140
gene id: 2325:TKV_RS09140
uniprot id: A0A097AT62
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Clade 'B2' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Non-allosteric.

2325:TKV RS10825
gene id: 2325:TKV_RS10825
uniprot id: A0A097AU48
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2325:TKV RS09040
gene id: 2325:TKV_RS09040
uniprot id: A0A097AT71
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MetX family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

2325:TKV RS09085
gene id: 2325:TKV_RS09085
uniprot id: A0A097AT51
names: Function
messages: May be involved in the biosynthesis of molybdopterin.

2325:TKV RS03115
gene id: 2325:TKV_RS03115
uniprot id: A0A097APT7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

2325:TKV RS06875
gene id: 2325:TKV_RS06875
uniprot id: A0A097AS03
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Cytoplasm
messages: Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.

2325:TKV RS00395
gene id: 2325:TKV_RS00395
uniprot id: A0A097AN93
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family.

2325:TKV RS03200
gene id: 2325:TKV_RS03200
uniprot id: A0A097APY0
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

2325:TKV RS02775
gene id: 2325:TKV_RS02775
uniprot id: A0A097APP9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

2325:TKV RS07225
gene id: 2325:TKV_RS07225
uniprot id: A0A097AS48
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

2325:TKV RS10315
gene id: 2325:TKV_RS10315
uniprot id: A0A097ATV5
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

2325:TKV RS07880
gene id: 2325:TKV_RS07880
uniprot id: A0A097ASH5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/UDP phosphorylase family.
messages: Catalyzes the reversible phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
messages: Homohexamer; trimer of homodimers.

2325:TKV RS11400
gene id: 2325:TKV_RS11400
uniprot id: A0A097AUI2
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

2325:TKV RS07035
gene id: 2325:TKV_RS07035
uniprot id: A0A097AS17
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

2325:TKV RS06075
gene id: 2325:TKV_RS06075
uniprot id: A0A097ARJ1
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.

2325:TKV RS04400
gene id: 2325:TKV_RS04400
uniprot id: A0A097AQL2
names: Function
names: Similarity
messages: ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.
messages: Belongs to the ParA family. MinD subfamily.

2325:TKV RS12120
gene id: 2325:TKV_RS12120
uniprot id: A0A097AUS6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

2325:TKV RS07000
gene id: 2325:TKV_RS07000
uniprot id: A0A097AS26
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PyrK family.
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Heterotetramer of 2 PyrK and 2 PyrD type B subunits.
messages: Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(+).

2325:TKV RS01305
gene id: 2325:TKV_RS01305
uniprot id: A0A097ANT4
names: Similarity
messages: Belongs to the FldB/FldC dehydratase alpha/beta subunit family.

2325:TKV RS05865
gene id: 2325:TKV_RS05865
uniprot id: A0A097ARE8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

2325:TKV RS06245
gene id: 2325:TKV_RS06245
uniprot id: A0A097ARK5
names: Function
names: Similarity
messages: Belongs to the RNase Y family.
messages: Endoribonuclease that initiates mRNA decay.

2325:TKV RS07665
gene id: 2325:TKV_RS07665
uniprot id: A0A097ASE0
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

2325:TKV RS02760
gene id: 2325:TKV_RS02760
uniprot id: A0A097APL4
names: Similarity
messages: Belongs to the SAICAR synthetase family.

2325:TKV RS05055
gene id: 2325:TKV_RS05055
uniprot id: A0A097AQX6
names: Induction
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SspI family.
messages: Expressed only in the forespore compartment of sporulating cells.
messages: Spore core

2325:TKV RS00695
gene id: 2325:TKV_RS00695
uniprot id: A0A097ANF1
names: Similarity
messages: Belongs to the HypE family.

2325:TKV RS00170
gene id: 2325:TKV_RS00170
uniprot id: A0A097AN52
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

2325:TKV RS03275
gene id: 2325:TKV_RS03275
uniprot id: A0A097APV5
names: Similarity
messages: Belongs to the polysaccharide synthase family.

2325:TKV RS02055
gene id: 2325:TKV_RS02055
uniprot id: A0A097AP93
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

2325:TKV RS00750
gene id: 2325:TKV_RS00750
uniprot id: A0A097ANG0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.

2325:TKV RS05770
gene id: 2325:TKV_RS05770
uniprot id: A0A097ARB2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

2325:TKV RS05750
gene id: 2325:TKV_RS05750
uniprot id: A0A097ARC9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

2325:TKV RS04615
gene id: 2325:TKV_RS04615
uniprot id: A0A097AQQ8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

2325:TKV RS10470
gene id: 2325:TKV_RS10470
uniprot id: A0A097ATY0
names: Cofactor
names: Similarity
messages: Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.
messages: Binds 3 [4Fe-4S] clusters per subunit.

2325:TKV RS04385
gene id: 2325:TKV_RS04385
uniprot id: A0A097AQK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Membrane

2325:TKV RS00035
gene id: 2325:TKV_RS00035
uniprot id: A0A097AN32
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MurCDEF family. MurT subfamily.
messages: Forms a heterodimer with GatD.
messages: The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The MurT subunit catalyzes the ATP-dependent amidation of D-glutamate residue of lipid II, converting it to an isoglutamine residue.

2325:TKV RS00180
gene id: 2325:TKV_RS00180
uniprot id: A0A097AN54
names: Similarity
messages: Belongs to the histone deacetylase family.

2325:TKV RS05065
gene id: 2325:TKV_RS05065
uniprot id: A0A097AR10
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

2325:TKV RS09920
gene id: 2325:TKV_RS09920
uniprot id: A0A097ATM8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

2325:TKV RS04890
gene id: 2325:TKV_RS04890
uniprot id: A0A097AQX0
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.

2325:TKV RS04885
gene id: 2325:TKV_RS04885
uniprot id: A0A097AQV1
names: Function
names: Similarity
messages: Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PDRP subfamily.
messages: Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation.

2325:TKV RS04305
gene id: 2325:TKV_RS04305
uniprot id: A0A097AQI9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

2325:TKV RS06640
gene id: 2325:TKV_RS06640
uniprot id: A0A097ARU0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

2325:TKV RS00130
gene id: 2325:TKV_RS00130
uniprot id: A0A097AN51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Cell membrane
messages: Membrane

2325:TKV RS04790
gene id: 2325:TKV_RS04790
uniprot id: A0A097AQT7
names: Similarity
messages: Belongs to the UPF0237 family.

2325:TKV RS01030
gene id: 2325:TKV_RS01030
uniprot id: A0A097ANM4
names: Subcellular Location Annotation
messages: Membrane

2325:TKV RS10845
gene id: 2325:TKV_RS10845
uniprot id: A0A097AU63
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

2325:TKV RS10085
gene id: 2325:TKV_RS10085
uniprot id: A0A097ATR1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

2325:TKV RS07455
gene id: 2325:TKV_RS07455
uniprot id: A0A097ASA2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

2325:TKV RS02755
gene id: 2325:TKV_RS02755
uniprot id: A0A097APL7
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

2325:TKV RS12030
gene id: 2325:TKV_RS12030
uniprot id: A0A097AUV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

2325:TKV RS03960
gene id: 2325:TKV_RS03960
uniprot id: A0A097AQ99
names: Function
names: Similarity
messages: Belongs to the alpha/beta-type SASP family.
messages: SASP are bound to spore DNA. They are double-stranded DNA-binding proteins that cause DNA to change to an a-like conformation. They protect the DNA backbone from chemical and enzymatic cleavage and are thus involved in dormant spore's high resistance to UV light.

2325:TKV RS05610
gene id: 2325:TKV_RS05610
uniprot id: A0A097AR94
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

2325:TKV RS07415
gene id: 2325:TKV_RS07415
uniprot id: A0A097AS97
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

2325:TKV RS10025
gene id: 2325:TKV_RS10025
uniprot id: A0A097ATQ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

2325:TKV RS05875
gene id: 2325:TKV_RS05875
uniprot id: A0A097ARF5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2325:TKV RS06265
gene id: 2325:TKV_RS06265
uniprot id: A0A097ARL9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane
messages: This protein catalyzes the committed step to the synthesis of the acidic phospholipids.

2325:TKV RS01345
gene id: 2325:TKV_RS01345
uniprot id: A0A097ANS0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2325:TKV RS00975
gene id: 2325:TKV_RS00975
uniprot id: A0A097ANM0
names: Subcellular Location Annotation
messages: Membrane

2325:TKV RS05390
gene id: 2325:TKV_RS05390
uniprot id: A0A097AR39
names: Similarity
messages: Belongs to the IMPACT family.

2325:TKV RS02315
gene id: 2325:TKV_RS02315
uniprot id: A0A097APB4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

2325:TKV RS01055
gene id: 2325:TKV_RS01055
uniprot id: A0A097ANM8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. AddB/RexB type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster.
messages: Heterodimer of AddA and AddB.
messages: The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddB nuclease domain is not required for chi fragment generation; this subunit has 5' -> 3' nuclease activity.

2325:TKV RS07510
gene id: 2325:TKV_RS07510
uniprot id: A0A097ASE3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2325:TKV RS01135
gene id: 2325:TKV_RS01135
uniprot id: A0A097ANP7
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by fructose 1,6-bisphosphate (FBP).
messages: Belongs to the LDH/MDH superfamily. LDH family.
messages: Catalyzes the conversion of lactate to pyruvate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2325:TKV RS10225
gene id: 2325:TKV_RS10225
uniprot id: A0A097ATT2
names: Similarity
messages: Belongs to the CtsR family.

2325:TKV RS05445
gene id: 2325:TKV_RS05445
uniprot id: A0A097AR65
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvB family.
messages: Forms a complex with RuvA.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.

2325:TKV RS08180
gene id: 2325:TKV_RS08180
uniprot id: A0A097ASN7
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

2325:TKV RS07425
gene id: 2325:TKV_RS07425
uniprot id: A0A097ASA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane

2325:TKV RS01690
gene id: 2325:TKV_RS01690
uniprot id: A0A097AP24
names: Subcellular Location Annotation
messages: Membrane

2325:TKV RS12060
gene id: 2325:TKV_RS12060
uniprot id: A0A097AUR6
names: Similarity
messages: Belongs to the ParB family.

2325:TKV RS04135
gene id: 2325:TKV_RS04135
uniprot id: A0A097AQF8
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

2325:TKV RS10295
gene id: 2325:TKV_RS10295
uniprot id: A0A097ATU7
names: Cofactor
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.

2325:TKV RS11415
gene id: 2325:TKV_RS11415
uniprot id: A0A097AUJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

2325:TKV RS08975
gene id: 2325:TKV_RS08975
uniprot id: A0A097AT63
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Lacks the C-terminal regulatory region which is replaced by HisZ.

2325:TKV RS01755
gene id: 2325:TKV_RS01755
uniprot id: A0A097AP27
names: Subcellular Location Annotation
messages: Membrane

2325:TKV RS06595
gene id: 2325:TKV_RS06595
uniprot id: A0A097ARV0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod.

2325:TKV RS10305
gene id: 2325:TKV_RS10305
uniprot id: A0A097ATV3
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

2325:TKV RS02370
gene id: 2325:TKV_RS02370
uniprot id: A0A097APE3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'-UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

2325:TKV RS00135
gene id: 2325:TKV_RS00135
uniprot id: A0A097AN49
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2325:TKV RS07640
gene id: 2325:TKV_RS07640
uniprot id: A0A097ASD5
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

2325:TKV RS07535
gene id: 2325:TKV_RS07535
uniprot id: A0A097ASE8
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2325:TKV RS04500
gene id: 2325:TKV_RS04500
uniprot id: A0A097AQN2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein L14 (rplN).

2325:TKV RS00340
gene id: 2325:TKV_RS00340
uniprot id: A0A097AN85
names: Similarity
messages: Belongs to the glycosyl hydrolase 130 family.

2325:TKV RS02385
gene id: 2325:TKV_RS02385
uniprot id: A0A097APG9
names: Function
names: Similarity
messages: A P subtype restriction enzyme that recognizes the double-stranded unmethylated sequence 5'-GATC-3'.
messages: Belongs to the DpnII type II restriction endonuclease family.

2325:TKV RS06455
gene id: 2325:TKV_RS06455
uniprot id: A0A097ARS1
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

2325:TKV RS04405
gene id: 2325:TKV_RS04405
uniprot id: A0A097AQI1
names: Function
names: Similarity
messages: Belongs to the MinE family.
messages: Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.

2325:TKV RS08220
gene id: 2325:TKV_RS08220
uniprot id: A0A097ASQ0
names: Similarity
messages: Belongs to the pyruvate kinase family.
messages: In the C-terminal section; belongs to the PEP-utilizing enzyme family.

2325:TKV RS09950
gene id: 2325:TKV_RS09950
uniprot id: A0A097ATN8
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

2325:TKV RS10410
gene id: 2325:TKV_RS10410
uniprot id: A0A097ATY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

2325:TKV RS03345
gene id: 2325:TKV_RS03345
uniprot id: A0A097APW8
names: Subcellular Location Annotation
messages: Membrane

2325:TKV RS06330
gene id: 2325:TKV_RS06330
uniprot id: A0A097ARP4
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

2325:TKV RS10060
gene id: 2325:TKV_RS10060
uniprot id: A0A097ATQ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

2325:TKV RS08810
gene id: 2325:TKV_RS08810
uniprot id: A0A097AT40
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

2325:TKV RS09570
gene id: 2325:TKV_RS09570
uniprot id: A0A097ATE5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Membrane

2325:TKV RS05595
gene id: 2325:TKV_RS05595
uniprot id: A0A097AR78
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

2325:TKV RS03505
gene id: 2325:TKV_RS03505
uniprot id: A0A097AQ07
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. CpsB/CapC family.

2325:TKV RS07010
gene id: 2325:TKV_RS07010
uniprot id: A0A097AS12
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2325:TKV RS05235
gene id: 2325:TKV_RS05235
uniprot id: A0A097AR21
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

2325:TKV RS06655
gene id: 2325:TKV_RS06655
uniprot id: A0A097ARW3
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

2325:TKV RS06070
gene id: 2325:TKV_RS06070
uniprot id: A0A097ARJ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the spermidine/spermine synthase family.
messages: Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
messages: Homodimer or homotetramer.

2325:TKV RS00780
gene id: 2325:TKV_RS00780
uniprot id: A0A097ANI7
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

2325:TKV RS08920
gene id: 2325:TKV_RS08920
uniprot id: A0A097AT61
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

2325:TKV RS02645
gene id: 2325:TKV_RS02645
uniprot id: A0A097APK0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transcriptional regulatory Rex family.
messages: Cytoplasm
messages: Homodimer.
messages: Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.

2325:TKV RS03560
gene id: 2325:TKV_RS03560
uniprot id: A0A097AQ25
names: Subcellular Location Annotation
messages: Membrane

2325:TKV RS00520
gene id: 2325:TKV_RS00520
uniprot id: A0A097ANB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arginine deiminase family.
messages: Cytoplasm

2325:TKV RS03145
gene id: 2325:TKV_RS03145
uniprot id: A0A097APT2
names: Similarity
messages: Belongs to the EamA transporter family.

2325:TKV RS04520
gene id: 2325:TKV_RS04520
uniprot id: A0A097AQQ3
names: Similarity
messages: Belongs to the asparagine synthetase family.

2325:TKV RS11460
gene id: 2325:TKV_RS11460
uniprot id: A0A097AUJ8
names: Similarity
messages: Belongs to the EamA transporter family.

2325:TKV RS09365
gene id: 2325:TKV_RS09365
uniprot id: A0A097ATD7
names: Similarity
messages: Belongs to the phosphate acetyltransferase and butyryltransferase family.

2325:TKV RS10745
gene id: 2325:TKV_RS10745
uniprot id: A0A097AU42
names: Function
names: Similarity
messages: Belongs to the desulfoferrodoxin family.
messages: Catalyzes the one-electron reduction of superoxide anion radical to hydrogen peroxide at a nonheme ferrous iron center. Plays a fundamental role in case of oxidative stress via its superoxide detoxification activity.

2325:TKV RS01795
gene id: 2325:TKV_RS01795
uniprot id: A0A097AP44
names: Subcellular Location Annotation
messages: Membrane

2325:TKV RS01565
gene id: 2325:TKV_RS01565
uniprot id: A0A097ANX9
names: Function
messages: Decarboxylates L-threonine-O-3-phosphate to yield (R)-1-amino-2-propanol O-2-phosphate, the precursor for the linkage between the nucleotide loop and the corrin ring in cobalamin.

2325:TKV RS00455
gene id: 2325:TKV_RS00455
uniprot id: A0A097ANA0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

2325:TKV RS09645
gene id: 2325:TKV_RS09645
uniprot id: A0A097ATG2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

2325:TKV RS03650
gene id: 2325:TKV_RS03650
uniprot id: A0A097AQ65
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

2325:TKV RS09025
gene id: 2325:TKV_RS09025
uniprot id: A0A097AT82
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mediates influx of magnesium ions.
messages: Membrane

2325:TKV RS05600
gene id: 2325:TKV_RS05600
uniprot id: A0A097AR97
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

2325:TKV RS10105
gene id: 2325:TKV_RS10105
uniprot id: A0A097ATS2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

2325:TKV RS08580
gene id: 2325:TKV_RS08580
uniprot id: A0A097ASX5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the branched-chain polyamine synthase family.
messages: Cytoplasm
messages: Involved in the biosynthesis of branched-chain polyamines, which support the growth of thermophiles under high-temperature conditions. Catalyzes the sequential condensation of spermidine with the aminopropyl groups of decarboxylated S-adenosylmethionines to produce N(4)-bis(aminopropyl)spermidine via N(4)-aminopropylspermidine.

2325:TKV RS05185
gene id: 2325:TKV_RS05185
uniprot id: A0A097AR12
names: Similarity
messages: Belongs to the 6-phosphogluconate dehydrogenase family.

2325:TKV RS11660
gene id: 2325:TKV_RS11660
uniprot id: A0A097AUJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

2325:TKV RS07545
gene id: 2325:TKV_RS07545
uniprot id: A0A097ASC2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsL family.
messages: Cell membrane
messages: Essential cell division protein.
messages: Membrane

2325:TKV RS02250
gene id: 2325:TKV_RS02250
uniprot id: A0A097APD3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

2325:TKV RS00430
gene id: 2325:TKV_RS00430
uniprot id: A0A097ANB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0394 family.
messages: Membrane

2325:TKV RS09545
gene id: 2325:TKV_RS09545
uniprot id: A0A097ATI0
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

2325:TKV RS11535
gene id: 2325:TKV_RS11535
uniprot id: A0A097AUL1
names: Similarity
messages: In the N-terminal section; belongs to the CRISPR-associated nuclease Cas3-HD family.
messages: In the central section; belongs to the CRISPR-associated helicase Cas3 family.

2325:TKV RS03500
gene id: 2325:TKV_RS03500
uniprot id: A0A097APZ5
names: Similarity
messages: Belongs to the CpsD/CapB family.

2325:TKV RS03985
gene id: 2325:TKV_RS03985
uniprot id: A0A097AQA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

2325:TKV RS04250
gene id: 2325:TKV_RS04250
uniprot id: A0A097AQF1
names: Subcellular Location Annotation
messages: Membrane

2325:TKV RS06750
gene id: 2325:TKV_RS06750
uniprot id: A0A097ARY0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

2325:TKV RS01390
gene id: 2325:TKV_RS01390
uniprot id: A0A097ANV9
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II CmtAB PTS system is involved in D-mannitol transport.

2325:TKV RS06810
gene id: 2325:TKV_RS06810
uniprot id: A0A097ARX2
names: Function
names: Similarity
messages: Belongs to the alpha/beta-type SASP family.
messages: SASP are bound to spore DNA. They are double-stranded DNA-binding proteins that cause DNA to change to an a-like conformation. They protect the DNA backbone from chemical and enzymatic cleavage and are thus involved in dormant spore's high resistance to UV light.

2325:TKV RS10480
gene id: 2325:TKV_RS10480
uniprot id: A0A097ATY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

2325:TKV RS07525
gene id: 2325:TKV_RS07525
uniprot id: A0A097ASB5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

2325:TKV RS05530
gene id: 2325:TKV_RS05530
uniprot id: A0A097AR90
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

2325:TKV RS08510
gene id: 2325:TKV_RS08510
uniprot id: A0A097ASW0
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

2325:TKV RS06770
gene id: 2325:TKV_RS06770
uniprot id: A0A097ARY3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

2325:TKV RS11285
gene id: 2325:TKV_RS11285
uniprot id: A0A097AUG0
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

2325:TKV RS05685
gene id: 2325:TKV_RS05685
uniprot id: A0A097ARB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell membrane
messages: Membrane

2325:TKV RS05845
gene id: 2325:TKV_RS05845
uniprot id: A0A097ARC6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

2325:TKV RS02000
gene id: 2325:TKV_RS02000
uniprot id: A0A097AP84
names: Subcellular Location Annotation
messages: Membrane

2325:TKV RS06205
gene id: 2325:TKV_RS06205
uniprot id: A0A097ARL7
names: Similarity
messages: Belongs to the CbxX/CfxQ family.

2325:TKV RS03370
gene id: 2325:TKV_RS03370
uniprot id: A0A097APX3
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

2325:TKV RS00775
gene id: 2325:TKV_RS00775
uniprot id: A0A097ANG5
names: Subcellular Location Annotation
messages: Membrane

2325:TKV RS10720
gene id: 2325:TKV_RS10720
uniprot id: A0A097AU36
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

2325:TKV RS10150
gene id: 2325:TKV_RS10150
uniprot id: A0A097ATR8
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

2325:TKV RS06365
gene id: 2325:TKV_RS06365
uniprot id: A0A097ARN6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

2325:TKV RS10445
gene id: 2325:TKV_RS10445
uniprot id: A0A097ATY3
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

2325:TKV RS10050
gene id: 2325:TKV_RS10050
uniprot id: A0A097ATQ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

2325:TKV RS00745
gene id: 2325:TKV_RS00745
uniprot id: A0A097ANF9
names: Subcellular Location Annotation
messages: Membrane

2325:TKV RS07970
gene id: 2325:TKV_RS07970
uniprot id: A0A097ASI7
names: Similarity
messages: Belongs to the sigma-54 factor family.

2325:TKV RS12085
gene id: 2325:TKV_RS12085
uniprot id: A0A097AUW8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

2325:TKV RS09900
gene id: 2325:TKV_RS09900
uniprot id: A0A097ATN4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

2325:TKV RS01640
gene id: 2325:TKV_RS01640
uniprot id: A0A097AP13
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen.
messages: Homooctamer.

2325:TKV RS08400
gene id: 2325:TKV_RS08400
uniprot id: A0A097ASU1
names: Similarity
messages: Belongs to the UPF0251 family.

2325:TKV RS00590
gene id: 2325:TKV_RS00590
uniprot id: A0A097ANC9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

2325:TKV RS04785
gene id: 2325:TKV_RS04785
uniprot id: A0A097AQQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

2325:TKV RS02770
gene id: 2325:TKV_RS02770
uniprot id: A0A097APM0
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

2325:TKV RS05945
gene id: 2325:TKV_RS05945
uniprot id: A0A097ARH2
names: Similarity
messages: Belongs to the Nudix hydrolase family.

2325:TKV RS06315
gene id: 2325:TKV_RS06315
uniprot id: A0A097ARM9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

2325:TKV RS04525
gene id: 2325:TKV_RS04525
uniprot id: A0A097AQN8
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

2325:TKV RS06130
gene id: 2325:TKV_RS06130
uniprot id: A0A097ARK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

2325:TKV RS10310
gene id: 2325:TKV_RS10310
uniprot id: A0A097ATW6
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

2325:TKV RS06535
gene id: 2325:TKV_RS06535
uniprot id: A0A097ARR8
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

2325:TKV RS00620
gene id: 2325:TKV_RS00620
uniprot id: A0A097AND8
names: Subcellular Location Annotation
messages: Membrane

2325:TKV RS03535
gene id: 2325:TKV_RS03535
uniprot id: A0A097AQ20
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

2325:TKV RS06170
gene id: 2325:TKV_RS06170
uniprot id: A0A097ARI9
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

2325:TKV RS05440
gene id: 2325:TKV_RS05440
uniprot id: A0A097AR51
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

2325:TKV RS07520
gene id: 2325:TKV_RS07520
uniprot id: A0A097ASB7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

2325:TKV RS10910
gene id: 2325:TKV_RS10910
uniprot id: A0A097AU71
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

2325:TKV RS04145
gene id: 2325:TKV_RS04145
uniprot id: A0A097AQI3
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

2325:TKV RS00115
gene id: 2325:TKV_RS00115
uniprot id: A0A097AN75
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

2325:TKV RS05525
gene id: 2325:TKV_RS05525
uniprot id: A0A097AR81
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

2325:TKV RS08340
gene id: 2325:TKV_RS08340
uniprot id: A0A097ASV2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2325:TKV RS02765
gene id: 2325:TKV_RS02765
uniprot id: A0A097APM3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

2325:TKV RS05280
gene id: 2325:TKV_RS05280
uniprot id: A0A097AR20
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-I family.

2325:TKV RS01680
gene id: 2325:TKV_RS01680
uniprot id: A0A097AP12
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane
messages: Part of an ABC transporter complex. Responsible for energy coupling to the transport system.

2325:TKV RS09340
gene id: 2325:TKV_RS09340
uniprot id: A0A097ATD3
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

2325:TKV RS07430
gene id: 2325:TKV_RS07430
uniprot id: A0A097AS98
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

2325:TKV RS10040
gene id: 2325:TKV_RS10040
uniprot id: A0A097ATQ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

2325:TKV RS05570
gene id: 2325:TKV_RS05570
uniprot id: A0A097AR73
names: Similarity
messages: Belongs to the thioredoxin family.

2325:TKV RS06625
gene id: 2325:TKV_RS06625
uniprot id: A0A097ARV6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

2325:TKV RS04560
gene id: 2325:TKV_RS04560
uniprot id: A0A097AQL6
names: Similarity
messages: Belongs to the P-Pant transferase superfamily. Gsp/Sfp/HetI/AcpT family.

2325:TKV RS11265
gene id: 2325:TKV_RS11265
uniprot id: A0A097AUD3
names: Similarity
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.

2325:TKV RS11635
gene id: 2325:TKV_RS11635
uniprot id: A0A097AUJ5
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

2325:TKV RS10350
gene id: 2325:TKV_RS10350
uniprot id: A0A097ATW0
names: Similarity
messages: Belongs to the GerABKC lipoprotein family.

2325:TKV RS08910
gene id: 2325:TKV_RS08910
uniprot id: A0A097AT53
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpA family.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds the extracellular potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

2325:TKV RS08205
gene id: 2325:TKV_RS08205
uniprot id: A0A097ASP2
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

2325:TKV RS07630
gene id: 2325:TKV_RS07630
uniprot id: A0A097ASD2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

2325:TKV RS05435
gene id: 2325:TKV_RS05435
uniprot id: A0A097AR54
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RuvC family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.

2325:TKV RS00150
gene id: 2325:TKV_RS00150
uniprot id: A0A097AN80
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

2325:TKV RS11120
gene id: 2325:TKV_RS11120
uniprot id: A0A097AUC2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

2325:TKV RS06945
gene id: 2325:TKV_RS06945
uniprot id: A0A097AS02
names: Function
names: Similarity
names: Subunit
messages: Associates with stalled 50S ribosomal subunits.
messages: Belongs to the NEMF family.
messages: Part of the ribosome quality control system (RQC). Recruits Ala-charged tRNA and directs the elongation of stalled nascent chains on 50S ribosomal subunits, leading to non-templated C-terminal Ala extensions (Ala tail). The Ala tail promotes nascent chain degradation. May add between 1 and at least 8 Ala residues. Binds to stalled 50S ribosomal subunits.

2325:TKV RS09875
gene id: 2325:TKV_RS09875
uniprot id: A0A097ATN3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the energy-coupling factor EcfT family.
messages: Cell membrane
messages: Forms a stable energy-coupling factor (ECF) transporter complex composed of 2 membrane-embedded substrate-binding proteins (S component), 2 ATP-binding proteins (A component) and 2 transmembrane proteins (T component).
messages: Membrane
messages: Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.

2325:TKV RS00965
gene id: 2325:TKV_RS00965
uniprot id: A0A097ANK8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

2325:TKV RS07955
gene id: 2325:TKV_RS07955
uniprot id: A0A097ASM3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

2325:TKV RS05550
gene id: 2325:TKV_RS05550
uniprot id: A0A097AR86
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

2325:TKV RS02230
gene id: 2325:TKV_RS02230
uniprot id: A0A097APA0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

2325:TKV RS11875
gene id: 2325:TKV_RS11875
uniprot id: A0A097AUS9
names: Similarity
messages: In the N-terminal section; belongs to the CRISPR-associated nuclease Cas3-HD family.
messages: In the central section; belongs to the CRISPR-associated helicase Cas3 family.

2325:TKV RS11135
gene id: 2325:TKV_RS11135
uniprot id: A0A097AUA9
names: Function
names: Similarity
messages: Belongs to the alpha/beta-type SASP family.
messages: SASP are bound to spore DNA. They are double-stranded DNA-binding proteins that cause DNA to change to an a-like conformation. They protect the DNA backbone from chemical and enzymatic cleavage and are thus involved in dormant spore's high resistance to UV light.

2325:TKV RS02265
gene id: 2325:TKV_RS02265
uniprot id: A0A097APB6
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

2325:TKV RS12045
gene id: 2325:TKV_RS12045
uniprot id: A0A097AUW4
names: Function
names: Similarity
messages: Belongs to the peptidase S51 family.
messages: Exopeptidase that catalyzes the hydrolytic cleavage of multi-L-arginyl-poly-L-aspartic acid (cyanophycin; a water-insoluble reserve polymer) into aspartate-arginine dipeptides.