228405:HNE RS17545
gene id: 228405:HNE_RS17545
uniprot id: Q0BWC3
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

228405:HNE RS16975
gene id: 228405:HNE_RS16975
uniprot id: Q0BWN7
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

228405:HNE RS10445
gene id: 228405:HNE_RS10445
uniprot id: Q0C0D5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

228405:HNE RS01970
gene id: 228405:HNE_RS01970
uniprot id: Q0C570
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

228405:HNE RS00720
gene id: 228405:HNE_RS00720
uniprot id: Q0C5W4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RuvC family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.

228405:HNE RS17445
gene id: 228405:HNE_RS17445
uniprot id: Q0BWE3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.

228405:HNE RS09975
gene id: 228405:HNE_RS09975
uniprot id: Q0C0M8
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

228405:HNE RS09950
gene id: 228405:HNE_RS09950
uniprot id: Q0C0N4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

228405:HNE RS12235
gene id: 228405:HNE_RS12235
uniprot id: Q0BZC2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SoxA family.
messages: Binds 2 heme groups per subunit.
messages: Heterodimer of SoxA and SoxX.
messages: Periplasm

228405:HNE RS05835
gene id: 228405:HNE_RS05835
uniprot id: Q0C2Z9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family.
messages: Membrane
messages: Required for nicotinamide riboside transport across the inner membrane.

228405:HNE RS03255
gene id: 228405:HNE_RS03255
uniprot id: Q0C4G2
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

228405:HNE RS07395
gene id: 228405:HNE_RS07395
uniprot id: Q0C235
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

228405:HNE RS17635
gene id: 228405:HNE_RS17635
uniprot id: Q0BWA5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Cytoplasm

228405:HNE RS00800
gene id: 228405:HNE_RS00800
uniprot id: Q0C5U8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

228405:HNE RS02650
gene id: 228405:HNE_RS02650
uniprot id: Q0C4T2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).

228405:HNE RS09930
gene id: 228405:HNE_RS09930
uniprot id: Q0C0N8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

228405:HNE RS03580
gene id: 228405:HNE_RS03580
uniprot id: Q0C498
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

228405:HNE RS02625
gene id: 228405:HNE_RS02625
uniprot id: Q0C4T7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acetylates the N-terminal alanine of ribosomal protein S18.
messages: Belongs to the acetyltransferase family. RimI subfamily.
messages: Cytoplasm

228405:HNE RS15425
gene id: 228405:HNE_RS15425
uniprot id: Q0BXK0
names: Function
messages: Acts on leucine, isoleucine and valine.

228405:HNE RS14835
gene id: 228405:HNE_RS14835
uniprot id: Q0BXW7
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

228405:HNE RS14520
gene id: 228405:HNE_RS14520
uniprot id: Q0BY29
names: Similarity
messages: Belongs to the MreC family.

228405:HNE RS09900
gene id: 228405:HNE_RS09900
uniprot id: Q0C0P4
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

228405:HNE RS11745
gene id: 228405:HNE_RS11745
uniprot id: Q0BZM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OpgD/OpgG family.
messages: Periplasm

228405:HNE RS10525
gene id: 228405:HNE_RS10525
uniprot id: Q0C0B8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

228405:HNE RS17195
gene id: 228405:HNE_RS17195
uniprot id: Q0BWJ4
names: Similarity
messages: Belongs to the TrpF family.

228405:HNE RS16550
gene id: 228405:HNE_RS16550
uniprot id: Q0BWX2
names: Subcellular Location Annotation
messages: Membrane

228405:HNE RS07565
gene id: 228405:HNE_RS07565
uniprot id: Q0C204
names: Similarity
messages: Belongs to the UPF0166 family.

228405:HNE RS02440
gene id: 228405:HNE_RS02440
uniprot id: Q0C4X3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gmhB family.
messages: Cytoplasm

228405:HNE RS11445
gene id: 228405:HNE_RS11445
uniprot id: Q0BZT3
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

228405:HNE RS09685
gene id: 228405:HNE_RS09685
uniprot id: Q0C0T5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

228405:HNE RS12930
gene id: 228405:HNE_RS12930
uniprot id: Q0BYY8
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

228405:HNE RS13715
gene id: 228405:HNE_RS13715
uniprot id: Q0BYJ2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

228405:HNE RS04340
gene id: 228405:HNE_RS04340
uniprot id: Q0C3U4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

228405:HNE RS06955
gene id: 228405:HNE_RS06955
uniprot id: Q0C2C5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

228405:HNE RS14875
gene id: 228405:HNE_RS14875
uniprot id: Q0BXV9
names: Similarity
messages: Belongs to the peptidase M17 family.

228405:HNE RS04445
gene id: 228405:HNE_RS04445
uniprot id: Q0C3S3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the R-transferase family. Bpt subfamily.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate.

228405:HNE RS08195
gene id: 228405:HNE_RS08195
uniprot id: Q0C1M6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell inner membrane
messages: Membrane

228405:HNE RS08020
gene id: 228405:HNE_RS08020
uniprot id: Q0C1R0
names: Cofactor
messages: Binds 1 Fe(2+) ion per subunit.

228405:HNE RS08290
gene id: 228405:HNE_RS08290
uniprot id: Q0C1K7
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

228405:HNE RS03145
gene id: 228405:HNE_RS03145
uniprot id: Q0C4I3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK.

228405:HNE RS14120
gene id: 228405:HNE_RS14120
uniprot id: Q0BYB2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

228405:HNE RS08590
gene id: 228405:HNE_RS08590
uniprot id: Q0C1E9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Catalyzes the dehydration of 6-phospho-D-gluconate to 2-dehydro-3-deoxy-6-phospho-D-gluconate.

228405:HNE RS06615
gene id: 228405:HNE_RS06615
uniprot id: Q0C2J3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

228405:HNE RS17165
gene id: 228405:HNE_RS17165
uniprot id: Q0BWK0
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

228405:HNE RS16650
gene id: 228405:HNE_RS16650
uniprot id: Q0BWV2
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

228405:HNE RS01500
gene id: 228405:HNE_RS01500
uniprot id: Q0C5G6
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

228405:HNE RS02515
gene id: 228405:HNE_RS02515
uniprot id: Q0C4V9
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.

228405:HNE RS04180
gene id: 228405:HNE_RS04180
uniprot id: Q0C3X9
names: Similarity
messages: Belongs to the YciI family.

228405:HNE RS02560
gene id: 228405:HNE_RS02560
uniprot id: Q0C4V0
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

228405:HNE RS10690
gene id: 228405:HNE_RS10690
uniprot id: Q0C084
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

228405:HNE RS07975
gene id: 228405:HNE_RS07975
uniprot id: Q0C1S0
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

228405:HNE RS02635
gene id: 228405:HNE_RS02635
uniprot id: Q0C4T5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a global negative controlling element, employing Fe(2+) as a cofactor to bind the operator of the repressed genes.
messages: Belongs to the Fur family.
messages: Cytoplasm
messages: Homodimer.

228405:HNE RS09250
gene id: 228405:HNE_RS09250
uniprot id: Q0C122
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GSP I family.
messages: Cell inner membrane
messages: Cleaved by prepilin peptidase.
messages: Component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm.
messages: Membrane
messages: Type II secretion is composed of four main components: the outer membrane complex, the inner membrane complex, the cytoplasmic secretion ATPase and the periplasm-spanning pseudopilus.

228405:HNE RS08800
gene id: 228405:HNE_RS08800
uniprot id: Q0C1A7
names: Similarity
messages: Belongs to the citrate synthase family.

228405:HNE RS03490
gene id: 228405:HNE_RS03490
uniprot id: Q0C4B4
names: Function
names: Similarity
messages: Belongs to the LpxK family.
messages: Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).

228405:HNE RS12100
gene id: 228405:HNE_RS12100
uniprot id: Q0BZF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

228405:HNE RS16060
gene id: 228405:HNE_RS16060
uniprot id: Q0BX73
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur, cytochrome b-556, and a hydrophobic anchor protein.

228405:HNE RS06295
gene id: 228405:HNE_RS06295
uniprot id: Q0C2Q6
names: Similarity
messages: Belongs to the FAD-binding monooxygenase family.

228405:HNE RS15870
gene id: 228405:HNE_RS15870
uniprot id: Q0BXA9
names: Similarity
messages: Belongs to the peptidase S41A family.

228405:HNE RS08910
gene id: 228405:HNE_RS08910
uniprot id: Q0C185
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

228405:HNE RS15095
gene id: 228405:HNE_RS15095
uniprot id: Q0BXR4
names: Subcellular Location Annotation
messages: Membrane

228405:HNE RS05285
gene id: 228405:HNE_RS05285
uniprot id: Q0C3A6
names: Function
names: Similarity
messages: Belongs to the MoaB/Mog family.
messages: May be involved in the biosynthesis of molybdopterin.

228405:HNE RS16290
gene id: 228405:HNE_RS16290
uniprot id: Q0BX26
names: Similarity
messages: Belongs to the PspA/IM30 family.

228405:HNE RS08670
gene id: 228405:HNE_RS08670
uniprot id: Q0C1D3
names: Subcellular Location Annotation
messages: Membrane

228405:HNE RS08420
gene id: 228405:HNE_RS08420
uniprot id: Q0C1I2
names: Similarity
messages: Belongs to the CopC family.

228405:HNE RS00310
gene id: 228405:HNE_RS00310
uniprot id: Q0C647
names: Similarity
messages: Belongs to the PRORSD1 family.

228405:HNE RS14035
gene id: 228405:HNE_RS14035
uniprot id: Q0BYC9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

228405:HNE RS08665
gene id: 228405:HNE_RS08665
uniprot id: Q0C1D4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell inner membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

228405:HNE RS09445
gene id: 228405:HNE_RS09445
uniprot id: Q0C0Y3
names: Cofactor
names: Function
messages: Accepts electrons from ETF and reduces ubiquinone.
messages: Binds 1 [4Fe-4S] cluster.

228405:HNE RS15280
gene id: 228405:HNE_RS15280
uniprot id: Q0BXM8
names: Subcellular Location Annotation
messages: Membrane

228405:HNE RS16095
gene id: 228405:HNE_RS16095
uniprot id: Q0BX66
names: Similarity
messages: Belongs to the UPF0235 family.

228405:HNE RS02370
gene id: 228405:HNE_RS02370
uniprot id: Q0C4Y8
names: Subunit
messages: Homotetramer.

228405:HNE RS05775
gene id: 228405:HNE_RS05775
uniprot id: Q0C311
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

228405:HNE RS09865
gene id: 228405:HNE_RS09865
uniprot id: Q0C0Q0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinylarginine dihydrolase family.
messages: Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO(2).
messages: Homodimer.

228405:HNE RS16510
gene id: 228405:HNE_RS16510
uniprot id: Q0BWY2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
messages: Homodimer.

228405:HNE RS02675
gene id: 228405:HNE_RS02675
uniprot id: Q0C4S7
names: Similarity
messages: Belongs to the pirin family.

228405:HNE RS04435
gene id: 228405:HNE_RS04435
uniprot id: Q0C3S5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

228405:HNE RS04800
gene id: 228405:HNE_RS04800
uniprot id: Q0C3K3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
messages: Belongs to the azoreductase type 1 family.
messages: Binds 1 FMN per subunit.
messages: Homodimer.
messages: Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones.

228405:HNE RS02885
gene id: 228405:HNE_RS02885
uniprot id: Q0C4N5
names: Function
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.

228405:HNE RS17865
gene id: 228405:HNE_RS17865
uniprot id: Q0C2Q4
names: Similarity
messages: Belongs to the glycosyl hydrolase 24 family.

228405:HNE RS13530
gene id: 228405:HNE_RS13530
uniprot id: Q0BYM8
names: Function
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
messages: Catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate and ammonia.

228405:HNE RS02260
gene id: 228405:HNE_RS02260
uniprot id: Q0C511
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Monomer.

228405:HNE RS01400
gene id: 228405:HNE_RS01400
uniprot id: Q0C5I1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

228405:HNE RS06780
gene id: 228405:HNE_RS06780
uniprot id: Q0C2G0
names: Subcellular Location Annotation
messages: Membrane

228405:HNE RS00085
gene id: 228405:HNE_RS00085
uniprot id: Q0C692
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

228405:HNE RS06685
gene id: 228405:HNE_RS06685
uniprot id: Q0C2H9
names: Similarity
messages: Belongs to the UPF0262 family.

228405:HNE RS08725
gene id: 228405:HNE_RS08725
uniprot id: Q0C1C2
names: Subcellular Location Annotation
messages: Cytoplasm

228405:HNE RS09995
gene id: 228405:HNE_RS09995
uniprot id: Q0C0M4
names: Similarity
messages: Belongs to the ribosome association toxin RatA family.

228405:HNE RS02065
gene id: 228405:HNE_RS02065
uniprot id: Q0C551
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

228405:HNE RS10910
gene id: 228405:HNE_RS10910
uniprot id: Q0C040
names: Similarity
messages: Belongs to the cytochrome P450 family.

228405:HNE RS07735
gene id: 228405:HNE_RS07735
uniprot id: Q0C1W7
names: Similarity
messages: Belongs to the PpiC/parvulin rotamase family.

228405:HNE RS09505
gene id: 228405:HNE_RS09505
uniprot id: Q0C0X1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell inner membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

228405:HNE RS04395
gene id: 228405:HNE_RS04395
uniprot id: Q0C3T3
names: Similarity
messages: Belongs to the AHA1 family.

228405:HNE RS01345
gene id: 228405:HNE_RS01345
uniprot id: Q0C5J1
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

228405:HNE RS13055
gene id: 228405:HNE_RS13055
uniprot id: Q0BYW3
names: Function
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.
messages: DNA-dependent ATPase that plays important roles in cellular responses to stalled DNA replication processes.

228405:HNE RS16560
gene id: 228405:HNE_RS16560
uniprot id: Q0BWX0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

228405:HNE RS14020
gene id: 228405:HNE_RS14020
uniprot id: Q0BYD2
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

228405:HNE RS11020
gene id: 228405:HNE_RS11020
uniprot id: Q0C019
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.

228405:HNE RS06885
gene id: 228405:HNE_RS06885
uniprot id: Q0C2D9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

228405:HNE RS09785
gene id: 228405:HNE_RS09785
uniprot id: Q0C0R6
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

228405:HNE RS11695
gene id: 228405:HNE_RS11695
uniprot id: Q0BZN2
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

228405:HNE RS11945
gene id: 228405:HNE_RS11945
uniprot id: Q0BZI1
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

228405:HNE RS08035
gene id: 228405:HNE_RS08035
uniprot id: Q0C1Q7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GDT1 family.
messages: Membrane

228405:HNE RS14855
gene id: 228405:HNE_RS14855
uniprot id: Q0BXW3
names: Similarity
messages: Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family. Bacterial alpha-2-macroglobulin subfamily.

228405:HNE RS06960
gene id: 228405:HNE_RS06960
uniprot id: Q0C2C4
names: Caution
names: Function
names: PTM
names: Similarity
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

228405:HNE RS16310
gene id: 228405:HNE_RS16310
uniprot id: Q0BX22
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Catalyzes the last two steps in the biosynthesis of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the DAO family.
messages: In the N-terminal section; belongs to the methyltransferase superfamily. tRNA (mnm(5)s(2)U34)-methyltransferase family.

228405:HNE RS00570
gene id: 228405:HNE_RS00570
uniprot id: Q0C5Z4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

228405:HNE RS08240
gene id: 228405:HNE_RS08240
uniprot id: Q0C1L7
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

228405:HNE RS02235
gene id: 228405:HNE_RS02235
uniprot id: Q0C516
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.

228405:HNE RS08700
gene id: 228405:HNE_RS08700
uniprot id: Q0C1C7
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

228405:HNE RS15210
gene id: 228405:HNE_RS15210
uniprot id: Q0BXP1
names: Function
names: Similarity
messages: Belongs to the bacterioferritin family.
messages: Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex.

228405:HNE RS01645
gene id: 228405:HNE_RS01645
uniprot id: Q0C5D6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.
messages: Cytoplasm

228405:HNE RS03870
gene id: 228405:HNE_RS03870
uniprot id: Q0C439
names: Function
names: Similarity
names: Subunit
messages: APS kinase catalyzes the synthesis of activated sulfate.
messages: Belongs to the APS kinase family.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
messages: Catalyzes the synthesis of activated sulfate.
messages: Heterodimer composed of CysD, the smaller subunit, and CysN.
messages: In the C-terminal section; belongs to the APS kinase family.
messages: In the N-terminal section; belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
messages: Proposed to provide activated sulfate for transfer to Nod factor. ATP sulfurylase may be the GTPase, regulating ATP sulfurylase activity.
messages: Sulfate-activating enzymes, NodP and NodQ, may be physically associated.
messages: With CysD forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.

228405:HNE RS06500
gene id: 228405:HNE_RS06500
uniprot id: Q0C2L6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmE/CycJ family.
messages: Cell inner membrane
messages: Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.

228405:HNE RS13460
gene id: 228405:HNE_RS13460
uniprot id: Q0BYP3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

228405:HNE RS14840
gene id: 228405:HNE_RS14840
uniprot id: Q0BXW6
names: Subcellular Location Annotation
messages: Membrane

228405:HNE RS01265
gene id: 228405:HNE_RS01265
uniprot id: Q0C5K7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of five rings (E,L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

228405:HNE RS17780
gene id: 228405:HNE_RS17780
uniprot id: Q0C433
names: Similarity
messages: Belongs to the N-acylglucosamine 2-epimerase family.

228405:HNE RS10635
gene id: 228405:HNE_RS10635
uniprot id: Q0C096
names: Similarity
messages: Belongs to the PpiC/parvulin rotamase family.

228405:HNE RS17205
gene id: 228405:HNE_RS17205
uniprot id: Q0BWJ3
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

228405:HNE RS09015
gene id: 228405:HNE_RS09015
uniprot id: Q0C167
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

228405:HNE RS13005
gene id: 228405:HNE_RS13005
uniprot id: Q0BYX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

228405:HNE RS11195
gene id: 228405:HNE_RS11195
uniprot id: Q0BZY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

228405:HNE RS00555
gene id: 228405:HNE_RS00555
uniprot id: Q0C5Z7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

228405:HNE RS17510
gene id: 228405:HNE_RS17510
uniprot id: Q0BWD0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Membrane

228405:HNE RS13710
gene id: 228405:HNE_RS13710
uniprot id: Q0BYJ3
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Multidrug efflux pump.

228405:HNE RS08735
gene id: 228405:HNE_RS08735
uniprot id: Q0C1C0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

228405:HNE RS00785
gene id: 228405:HNE_RS00785
uniprot id: Q0C5V1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell inner membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

228405:HNE RS09545
gene id: 228405:HNE_RS09545
uniprot id: Q0C0W3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

228405:HNE RS14110
gene id: 228405:HNE_RS14110
uniprot id: Q0BYB4
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: Methylated by PrmB.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

228405:HNE RS14215
gene id: 228405:HNE_RS14215
uniprot id: Q0BY91
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

228405:HNE RS00820
gene id: 228405:HNE_RS00820
uniprot id: Q0C5U4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

228405:HNE RS15155
gene id: 228405:HNE_RS15155
uniprot id: Q0BXQ2
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

228405:HNE RS15915
gene id: 228405:HNE_RS15915
uniprot id: Q0BXA0
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 3 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

228405:HNE RS08460
gene id: 228405:HNE_RS08460
uniprot id: Q0C1H2
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

228405:HNE RS10665
gene id: 228405:HNE_RS10665
uniprot id: Q0C090
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

228405:HNE RS01365
gene id: 228405:HNE_RS01365
uniprot id: Q0C5I7
names: Similarity
messages: Belongs to the type III secretion exporter family.

228405:HNE RS17640
gene id: 228405:HNE_RS17640
uniprot id: Q0BWA4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.

228405:HNE RS06570
gene id: 228405:HNE_RS06570
uniprot id: Q0C2K2
names: Subcellular Location Annotation
messages: Membrane

228405:HNE RS03435
gene id: 228405:HNE_RS03435
uniprot id: Q0C4C5
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

228405:HNE RS11120
gene id: 228405:HNE_RS11120
uniprot id: Q0C000
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

228405:HNE RS13870
gene id: 228405:HNE_RS13870
uniprot id: Q0BYG0
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

228405:HNE RS15930
gene id: 228405:HNE_RS15930
uniprot id: Q0BX97
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

228405:HNE RS16590
gene id: 228405:HNE_RS16590
uniprot id: Q0BWW4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

228405:HNE RS01590
gene id: 228405:HNE_RS01590
uniprot id: Q0C5E8
names: Similarity
messages: Belongs to the GST superfamily.

228405:HNE RS03690
gene id: 228405:HNE_RS03690
uniprot id: Q0C476
names: Similarity
messages: Belongs to the ros/MucR family.

228405:HNE RS01200
gene id: 228405:HNE_RS01200
uniprot id: Q0C5M0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliF family.
messages: Membrane
messages: The M ring may be actively involved in energy transduction.

228405:HNE RS05650
gene id: 228405:HNE_RS05650
uniprot id: Q0C336
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PNT beta subunit family.
messages: Cell inner membrane
messages: Membrane
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

228405:HNE RS09095
gene id: 228405:HNE_RS09095
uniprot id: Q0C152
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

228405:HNE RS14985
gene id: 228405:HNE_RS14985
uniprot id: Q0BXT7
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

228405:HNE RS13850
gene id: 228405:HNE_RS13850
uniprot id: Q0BYG5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

228405:HNE RS00415
gene id: 228405:HNE_RS00415
uniprot id: Q0C626
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0053 family. Hemolysin C subfamily.
messages: Membrane

228405:HNE RS14315
gene id: 228405:HNE_RS14315
uniprot id: Q0BY71
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit A family.

228405:HNE RS17470
gene id: 228405:HNE_RS17470
uniprot id: Q0BWD8
names: Similarity
messages: Belongs to the HpcH/HpaI aldolase family.

228405:HNE RS17335
gene id: 228405:HNE_RS17335
uniprot id: Q0BWG6
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

228405:HNE RS08560
gene id: 228405:HNE_RS08560
uniprot id: Q0C1F4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

228405:HNE RS03215
gene id: 228405:HNE_RS03215
uniprot id: Q0C4H0
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

228405:HNE RS10450
gene id: 228405:HNE_RS10450
uniprot id: Q0C0D4
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

228405:HNE RS02765
gene id: 228405:HNE_RS02765
uniprot id: Q0C4R0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Monomer.

228405:HNE RS01820
gene id: 228405:HNE_RS01820
uniprot id: Q0C5A0
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

228405:HNE RS06820
gene id: 228405:HNE_RS06820
uniprot id: Q0C2F2
names: Function
names: Similarity
messages: Belongs to the glutamate--cysteine ligase type 2 family. EgtA subfamily.
messages: Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC).

228405:HNE RS00970
gene id: 228405:HNE_RS00970
uniprot id: Q0C5R4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Monomer.

228405:HNE RS09180
gene id: 228405:HNE_RS09180
uniprot id: Q0C135
names: Subcellular Location Annotation
messages: Cell outer membrane

228405:HNE RS10360
gene id: 228405:HNE_RS10360
uniprot id: Q0C0F3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

228405:HNE RS11640
gene id: 228405:HNE_RS11640
uniprot id: Q0BZP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

228405:HNE RS02070
gene id: 228405:HNE_RS02070
uniprot id: Q0C550
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

228405:HNE RS05150
gene id: 228405:HNE_RS05150
uniprot id: Q0C3D3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Binds a copper A center.
messages: Cell membrane
messages: Membrane
messages: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).

228405:HNE RS12650
gene id: 228405:HNE_RS12650
uniprot id: Q0BZ42
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

228405:HNE RS02305
gene id: 228405:HNE_RS02305
uniprot id: Q0C502
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

228405:HNE RS04550
gene id: 228405:HNE_RS04550
uniprot id: Q0C3Q3
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

228405:HNE RS11600
gene id: 228405:HNE_RS11600
uniprot id: Q0BZQ1
names: Subcellular Location Annotation
messages: Membrane

228405:HNE RS09485
gene id: 228405:HNE_RS09485
uniprot id: Q0C0X5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

228405:HNE RS12690
gene id: 228405:HNE_RS12690
uniprot id: Q0BZ34
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

228405:HNE RS06580
gene id: 228405:HNE_RS06580
uniprot id: Q0C2K0
names: Similarity
messages: Belongs to the UPF0145 family.

228405:HNE RS09775
gene id: 228405:HNE_RS09775
uniprot id: Q0C0R8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: Forms a 24-polypeptide structural core with octahedral symmetry.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

228405:HNE RS16995
gene id: 228405:HNE_RS16995
uniprot id: Q0BWN3
names: Similarity
messages: Belongs to the UPF0386 family.

228405:HNE RS13835
gene id: 228405:HNE_RS13835
uniprot id: Q0BYG8
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

228405:HNE RS09680
gene id: 228405:HNE_RS09680
uniprot id: Q0C0T6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

228405:HNE RS03075
gene id: 228405:HNE_RS03075
uniprot id: Q0C4J7
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
messages: O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.

228405:HNE RS14125
gene id: 228405:HNE_RS14125
uniprot id: Q0BYB1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

228405:HNE RS01660
gene id: 228405:HNE_RS01660
uniprot id: Q0C5D3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoH subfamily.
messages: Cytoplasm
messages: Interacts with the RNA polymerase core enzyme.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes.

228405:HNE RS14080
gene id: 228405:HNE_RS14080
uniprot id: Q0BYC0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

228405:HNE RS00730
gene id: 228405:HNE_RS00730
uniprot id: Q0C5W2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvB family.
messages: Forms a complex with RuvA.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.

228405:HNE RS01055
gene id: 228405:HNE_RS01055
uniprot id: Q0C5P7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

228405:HNE RS01095
gene id: 228405:HNE_RS01095
uniprot id: Q0C5N9
names: Similarity
messages: Belongs to the peptidase S45 family.

228405:HNE RS09165
gene id: 228405:HNE_RS09165
uniprot id: Q0C138
names: Cofactor
names: Similarity
messages: Belongs to the nitroreductase family.
messages: Binds 1 FMN per subunit.

228405:HNE RS17160
gene id: 228405:HNE_RS17160
uniprot id: Q0BWK1
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

228405:HNE RS00220
gene id: 228405:HNE_RS00220
uniprot id: Q0C665
names: Similarity
messages: Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.

228405:HNE RS13680
gene id: 228405:HNE_RS13680
uniprot id: Q0BYJ9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

228405:HNE RS00320
gene id: 228405:HNE_RS00320
uniprot id: Q0C645
names: Similarity
messages: Belongs to the PRA-PH family.

228405:HNE RS05470
gene id: 228405:HNE_RS05470
uniprot id: Q0C369
names: Similarity
messages: Belongs to the PrpD family.

228405:HNE RS06835
gene id: 228405:HNE_RS06835
uniprot id: Q0C2E9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

228405:HNE RS01215
gene id: 228405:HNE_RS01215
uniprot id: Q0C5L7
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliP/MopC/SpaP family.
messages: Membrane

228405:HNE RS13645
gene id: 228405:HNE_RS13645
uniprot id: Q0BYK6
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.

228405:HNE RS10465
gene id: 228405:HNE_RS10465
uniprot id: Q0C0D1
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the peroxidase family. Peroxidase/catalase subfamily.
messages: Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.
messages: Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.
messages: Homodimer or homotetramer.

228405:HNE RS16330
gene id: 228405:HNE_RS16330
uniprot id: Q0BX18
names: Similarity
messages: Belongs to the UPF0260 family.

228405:HNE RS06135
gene id: 228405:HNE_RS06135
uniprot id: Q0C2T8
names: Similarity
messages: Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family.

228405:HNE RS09800
gene id: 228405:HNE_RS09800
uniprot id: Q0C0R3
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

228405:HNE RS15735
gene id: 228405:HNE_RS15735
uniprot id: Q0BXD7
names: Similarity
messages: Belongs to the class I fructose-bisphosphate aldolase family.

228405:HNE RS17000
gene id: 228405:HNE_RS17000
uniprot id: Q0BWN2
names: Similarity
messages: Belongs to the Gfa family.

228405:HNE RS00750
gene id: 228405:HNE_RS00750
uniprot id: Q0C5V8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

228405:HNE RS15495
gene id: 228405:HNE_RS15495
uniprot id: Q0BXI6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

228405:HNE RS05225
gene id: 228405:HNE_RS05225
uniprot id: Q0C3B7
names: Subcellular Location Annotation
messages: Membrane

228405:HNE RS04485
gene id: 228405:HNE_RS04485
uniprot id: Q0C3R5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

228405:HNE RS10765
gene id: 228405:HNE_RS10765
uniprot id: Q0C069
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

228405:HNE RS07390
gene id: 228405:HNE_RS07390
uniprot id: Q0C236
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

228405:HNE RS11855
gene id: 228405:HNE_RS11855
uniprot id: Q0BZK0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urocanase family.
messages: Binds 1 NAD(+) per subunit.
messages: Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
messages: Cytoplasm

228405:HNE RS03685
gene id: 228405:HNE_RS03685
uniprot id: Q0C477
names: Subcellular Location Annotation
messages: Membrane

228405:HNE RS07345
gene id: 228405:HNE_RS07345
uniprot id: Q0C246
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

228405:HNE RS00530
gene id: 228405:HNE_RS00530
uniprot id: Q0C602
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell inner membrane
messages: Membrane

228405:HNE RS01195
gene id: 228405:HNE_RS01195
uniprot id: Q0C5M1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell inner membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

228405:HNE RS02770
gene id: 228405:HNE_RS02770
uniprot id: Q0C4Q9
names: Function
names: Similarity
messages: Belongs to the esterase D family.
messages: Serine hydrolase involved in the detoxification of formaldehyde.

228405:HNE RS10660
gene id: 228405:HNE_RS10660
uniprot id: Q0C091
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase MltG family.
messages: Cell inner membrane
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

228405:HNE RS06065
gene id: 228405:HNE_RS06065
uniprot id: Q0C2V2
names: Similarity
messages: Belongs to the GST superfamily.

228405:HNE RS14620
gene id: 228405:HNE_RS14620
uniprot id: Q0BY09
names: Similarity
messages: Belongs to the group II decarboxylase family.

228405:HNE RS16410
gene id: 228405:HNE_RS16410
uniprot id: Q0BX02
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

228405:HNE RS15180
gene id: 228405:HNE_RS15180
uniprot id: Q0BXP7
names: Similarity
messages: Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.

228405:HNE RS02645
gene id: 228405:HNE_RS02645
uniprot id: Q0C4T3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

228405:HNE RS15945
gene id: 228405:HNE_RS15945
uniprot id: Q0BX95
names: Subcellular Location Annotation
messages: Membrane

228405:HNE RS09585
gene id: 228405:HNE_RS09585
uniprot id: Q0C0V5
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

228405:HNE RS05770
gene id: 228405:HNE_RS05770
uniprot id: Q0C312
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

228405:HNE RS02570
gene id: 228405:HNE_RS02570
uniprot id: Q0C4U8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.

228405:HNE RS05170
gene id: 228405:HNE_RS05170
uniprot id: Q0C3C8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

228405:HNE RS16355
gene id: 228405:HNE_RS16355
uniprot id: Q0BX13
names: Similarity
messages: Belongs to the AHA1 family.

228405:HNE RS14795
gene id: 228405:HNE_RS14795
uniprot id: Q0BXX5
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

228405:HNE RS10035
gene id: 228405:HNE_RS10035
uniprot id: Q0C0L7
names: Function
messages: This protein is a positive regulator for the phosphate regulon. Transcription of this operon is positively regulated by PhoB and PhoR when phosphate is limited.

228405:HNE RS10255
gene id: 228405:HNE_RS10255
uniprot id: Q0C0H3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family.
messages: Membrane

228405:HNE RS00405
gene id: 228405:HNE_RS00405
uniprot id: Q0C628
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

228405:HNE RS13525
gene id: 228405:HNE_RS13525
uniprot id: Q0BYN0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TrkH potassium transport family.
messages: Cell inner membrane
messages: Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA.
messages: Membrane

228405:HNE RS02800
gene id: 228405:HNE_RS02800
uniprot id: Q0C4Q3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

228405:HNE RS13455
gene id: 228405:HNE_RS13455
uniprot id: Q0BYP4
names: Similarity
messages: Belongs to the GcvT family.

228405:HNE RS15675
gene id: 228405:HNE_RS15675
uniprot id: Q0BXE9
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.

228405:HNE RS09370
gene id: 228405:HNE_RS09370
uniprot id: Q0C0Z8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

228405:HNE RS08675
gene id: 228405:HNE_RS08675
uniprot id: Q0C1D2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

228405:HNE RS14970
gene id: 228405:HNE_RS14970
uniprot id: Q0BXU0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

228405:HNE RS11305
gene id: 228405:HNE_RS11305
uniprot id: Q0BZW2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

228405:HNE RS16475
gene id: 228405:HNE_RS16475
uniprot id: Q0BWY9
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.

228405:HNE RS01175
gene id: 228405:HNE_RS01175
uniprot id: Q0C5M5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

228405:HNE RS12430
gene id: 228405:HNE_RS12430
uniprot id: Q0BZ83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP G family.
messages: Cell inner membrane
messages: Membrane

228405:HNE RS08090
gene id: 228405:HNE_RS08090
uniprot id: Q0C1P6
names: Function
names: Similarity
messages: Belongs to the acetyltransferase family. EctA subfamily.
messages: Catalyzes the acetylation of L-2,4-diaminobutyrate (DABA) to gamma-N-acetyl-alpha,gamma-diaminobutyric acid (ADABA) with acetyl coenzyme A.

228405:HNE RS01050
gene id: 228405:HNE_RS01050
uniprot id: Q0C5P8
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

228405:HNE RS00810
gene id: 228405:HNE_RS00810
uniprot id: Q0C5U6
names: Function
names: Similarity
messages: Belongs to the SELO family.
messages: Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).

228405:HNE RS06725
gene id: 228405:HNE_RS06725
uniprot id: Q0C2H1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

228405:HNE RS10365
gene id: 228405:HNE_RS10365
uniprot id: Q0C0F2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

228405:HNE RS14960
gene id: 228405:HNE_RS14960
uniprot id: Q0BXU2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell inner membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).

228405:HNE RS08770
gene id: 228405:HNE_RS08770
uniprot id: Q0C1B3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamA family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

228405:HNE RS02095
gene id: 228405:HNE_RS02095
uniprot id: Q0C545
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

228405:HNE RS00515
gene id: 228405:HNE_RS00515
uniprot id: Q0C605
names: Similarity
messages: Belongs to the PhoH family.

228405:HNE RS10240
gene id: 228405:HNE_RS10240
uniprot id: Q0C0H6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

228405:HNE RS14070
gene id: 228405:HNE_RS14070
uniprot id: Q0BYC2
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

228405:HNE RS14800
gene id: 228405:HNE_RS14800
uniprot id: Q0BXX4
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

228405:HNE RS16245
gene id: 228405:HNE_RS16245
uniprot id: Q0BX36
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

228405:HNE RS04770
gene id: 228405:HNE_RS04770
uniprot id: Q0C3K8
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

228405:HNE RS11290
gene id: 228405:HNE_RS11290
uniprot id: Q0BZW5
names: Subcellular Location Annotation
messages: Membrane

228405:HNE RS02275
gene id: 228405:HNE_RS02275
uniprot id: Q0C508
names: Similarity
messages: Belongs to the YkuD family.

228405:HNE RS04470
gene id: 228405:HNE_RS04470
uniprot id: Q0C3R8
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

228405:HNE RS08760
gene id: 228405:HNE_RS08760
uniprot id: Q0C1B5
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

228405:HNE RS00565
gene id: 228405:HNE_RS00565
uniprot id: Q0C5Z5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

228405:HNE RS03780
gene id: 228405:HNE_RS03780
uniprot id: Q0C457
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

228405:HNE RS09345
gene id: 228405:HNE_RS09345
uniprot id: Q0C103
names: Similarity
messages: Belongs to the adrenodoxin/putidaredoxin family.

228405:HNE RS02410
gene id: 228405:HNE_RS02410
uniprot id: Q0C4X9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

228405:HNE RS16425
gene id: 228405:HNE_RS16425
uniprot id: Q0BWZ9
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

228405:HNE RS08635
gene id: 228405:HNE_RS08635
uniprot id: Q0C1E0
names: Function
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

228405:HNE RS00210
gene id: 228405:HNE_RS00210
uniprot id: Q0C667
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

228405:HNE RS08415
gene id: 228405:HNE_RS08415
uniprot id: Q0C1I3
names: Subcellular Location Annotation
messages: Membrane

228405:HNE RS09050
gene id: 228405:HNE_RS09050
uniprot id: Q0C161
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Monomer.

228405:HNE RS06740
gene id: 228405:HNE_RS06740
uniprot id: Q0C2G8
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

228405:HNE RS09240
gene id: 228405:HNE_RS09240
uniprot id: Q0C124
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP G family.
messages: Cell inner membrane
messages: Membrane

228405:HNE RS04850
gene id: 228405:HNE_RS04850
uniprot id: Q0C3J1
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

228405:HNE RS13840
gene id: 228405:HNE_RS13840
uniprot id: Q0BYG7
names: Similarity
messages: Belongs to the cytochrome P450 family.

228405:HNE RS06200
gene id: 228405:HNE_RS06200
uniprot id: Q0C2S6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

228405:HNE RS00930
gene id: 228405:HNE_RS00930
uniprot id: Q0C5S2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

228405:HNE RS08830
gene id: 228405:HNE_RS08830
uniprot id: Q0C1A1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.

228405:HNE RS16045
gene id: 228405:HNE_RS16045
uniprot id: Q0BX76
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD.

228405:HNE RS02185
gene id: 228405:HNE_RS02185
uniprot id: Q0C526
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

228405:HNE RS00090
gene id: 228405:HNE_RS00090
uniprot id: Q0C691
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

228405:HNE RS00005
gene id: 228405:HNE_RS00005
uniprot id: Q0C6A8
names: Function
names: Similarity
messages: Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PDRP subfamily.
messages: Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation.

228405:HNE RS16660
gene id: 228405:HNE_RS16660
uniprot id: Q0BWV0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

228405:HNE RS06330
gene id: 228405:HNE_RS06330
uniprot id: Q0C2P9
names: Caution
names: Similarity
messages: Belongs to the NTE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

228405:HNE RS11060
gene id: 228405:HNE_RS11060
uniprot id: Q0C011
names: Subcellular Location Annotation
messages: Membrane

228405:HNE RS07040
gene id: 228405:HNE_RS07040
uniprot id: Q0C2A8
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

228405:HNE RS15765
gene id: 228405:HNE_RS15765
uniprot id: Q0BXD1
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

228405:HNE RS10095
gene id: 228405:HNE_RS10095
uniprot id: Q0C0K5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

228405:HNE RS02890
gene id: 228405:HNE_RS02890
uniprot id: Q0C4N4
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

228405:HNE RS04625
gene id: 228405:HNE_RS04625
uniprot id: Q0C3N7
names: Similarity
messages: Belongs to the YkuD family.

228405:HNE RS09490
gene id: 228405:HNE_RS09490
uniprot id: Q0C0X4
names: Function
names: Similarity
messages: A possible function for this protein is to guide the assembly of the membrane sector of the ATPase enzyme complex.
messages: Belongs to the bacterial AtpI family.

228405:HNE RS05870
gene id: 228405:HNE_RS05870
uniprot id: Q0C2Z1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

228405:HNE RS03415
gene id: 228405:HNE_RS03415
uniprot id: Q0C4C9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

228405:HNE RS01225
gene id: 228405:HNE_RS01225
uniprot id: Q0C5L5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgI family.
messages: Periplasm
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

228405:HNE RS00815
gene id: 228405:HNE_RS00815
uniprot id: Q0C5U5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

228405:HNE RS07665
gene id: 228405:HNE_RS07665
uniprot id: Q0C1Y1
names: Function
names: Similarity
messages: Belongs to the MoaB/Mog family.
messages: May be involved in the biosynthesis of molybdopterin.

228405:HNE RS12090
gene id: 228405:HNE_RS12090
uniprot id: Q0BZF2
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

228405:HNE RS15490
gene id: 228405:HNE_RS15490
uniprot id: Q0BXI7
names: Subcellular Location Annotation
messages: Membrane

228405:HNE RS06830
gene id: 228405:HNE_RS06830
uniprot id: Q0C2F0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Membrane

228405:HNE RS16905
gene id: 228405:HNE_RS16905
uniprot id: Q0BWQ2
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

228405:HNE RS12920
gene id: 228405:HNE_RS12920
uniprot id: Q0BYZ0
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.

228405:HNE RS15810
gene id: 228405:HNE_RS15810
uniprot id: Q0BXC2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also edits incorrectly charged L-seryl-tRNA(Thr).
messages: Cytoplasm
messages: Homodimer.

228405:HNE RS00235
gene id: 228405:HNE_RS00235
uniprot id: Q0C662
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

228405:HNE RS11560
gene id: 228405:HNE_RS11560
uniprot id: Q0BZR2
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

228405:HNE RS09025
gene id: 228405:HNE_RS09025
uniprot id: Q0C165
names: Similarity
messages: Belongs to the HIBADH-related family.

228405:HNE RS14360
gene id: 228405:HNE_RS14360
uniprot id: Q0BY60
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

228405:HNE RS09185
gene id: 228405:HNE_RS09185
uniprot id: Q0C134
names: Subcellular Location Annotation
messages: Membrane

228405:HNE RS03530
gene id: 228405:HNE_RS03530
uniprot id: Q0C4A8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Maintains high levels of reduced glutathione.

228405:HNE RS09235
gene id: 228405:HNE_RS09235
uniprot id: Q0C125
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

228405:HNE RS17560
gene id: 228405:HNE_RS17560
uniprot id: Q0BWC0
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

228405:HNE RS16640
gene id: 228405:HNE_RS16640
uniprot id: Q0BWV4
names: Similarity
messages: Belongs to the SDHAF4 family.

228405:HNE RS10745
gene id: 228405:HNE_RS10745
uniprot id: Q0C072
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

228405:HNE RS00295
gene id: 228405:HNE_RS00295
uniprot id: Q0C650
names: Similarity
messages: Belongs to the AHA1 family.

228405:HNE RS06665
gene id: 228405:HNE_RS06665
uniprot id: Q0C2I3
names: Similarity
messages: Belongs to the cytochrome P450 family.

228405:HNE RS10065
gene id: 228405:HNE_RS10065
uniprot id: Q0C0L1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
messages: Belongs to the ClpX chaperone family. HslU subfamily.
messages: Cytoplasm

228405:HNE RS17390
gene id: 228405:HNE_RS17390
uniprot id: Q0BWF5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmC/CycZ/HelC family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

228405:HNE RS10440
gene id: 228405:HNE_RS10440
uniprot id: Q0C0D6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

228405:HNE RS03210
gene id: 228405:HNE_RS03210
uniprot id: Q0C4H1
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

228405:HNE RS04230
gene id: 228405:HNE_RS04230
uniprot id: Q0C3W7
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

228405:HNE RS16840
gene id: 228405:HNE_RS16840
uniprot id: Q0BWR4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Monomer.
messages: Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.

228405:HNE RS02850
gene id: 228405:HNE_RS02850
uniprot id: Q0C4P3
names: Cofactor
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Binds 1 Fe(3+) ion per subunit.

228405:HNE RS09530
gene id: 228405:HNE_RS09530
uniprot id: Q0C0W6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

228405:HNE RS02355
gene id: 228405:HNE_RS02355
uniprot id: Q0C4Z1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1C family.
messages: Periplasm

228405:HNE RS07260
gene id: 228405:HNE_RS07260
uniprot id: Q0C263
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

228405:HNE RS04035
gene id: 228405:HNE_RS04035
uniprot id: Q0C407
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

228405:HNE RS05430
gene id: 228405:HNE_RS05430
uniprot id: Q0C377
names: Function
names: Similarity
messages: Belongs to the polysaccharide deacetylase family.
messages: Is involved in generating a small heat-stable compound (Nod), an acylated oligomer of N-acetylglucosamine, that stimulates mitosis in various plant protoplasts.

228405:HNE RS00520
gene id: 228405:HNE_RS00520
uniprot id: Q0C604
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

228405:HNE RS09255
gene id: 228405:HNE_RS09255
uniprot id: Q0C121
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP J family.
messages: Cell inner membrane
messages: Membrane

228405:HNE RS09745
gene id: 228405:HNE_RS09745
uniprot id: Q0C0S4
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

228405:HNE RS13955
gene id: 228405:HNE_RS13955
uniprot id: Q0BYE5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

228405:HNE RS16365
gene id: 228405:HNE_RS16365
uniprot id: Q0BX11
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

228405:HNE RS07620
gene id: 228405:HNE_RS07620
uniprot id: Q0C1Z3
names: Subcellular Location Annotation
messages: Cytoplasm

228405:HNE RS03750
gene id: 228405:HNE_RS03750
uniprot id: Q0C463
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

228405:HNE RS17600
gene id: 228405:HNE_RS17600
uniprot id: Q0BWB2
names: Function
names: Similarity
messages: Belongs to the ParB family.
messages: Involved in chromosome partition. Localize to both poles of the predivisional cell following completion of DNA replication. Binds to the DNA origin of replication.

228405:HNE RS02155
gene id: 228405:HNE_RS02155
uniprot id: Q0C533
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

228405:HNE RS16275
gene id: 228405:HNE_RS16275
uniprot id: Q0BX30
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

228405:HNE RS06245
gene id: 228405:HNE_RS06245
uniprot id: Q0C2R7
names: Similarity
messages: Belongs to the TonB-dependent receptor family.

228405:HNE RS09765
gene id: 228405:HNE_RS09765
uniprot id: Q0C0S0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

228405:HNE RS10775
gene id: 228405:HNE_RS10775
uniprot id: Q0C067
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

228405:HNE RS08100
gene id: 228405:HNE_RS08100
uniprot id: Q0C1P4
names: Function
names: Similarity
messages: Belongs to the ectoine synthase family.
messages: Catalyzes the circularization of gamma-N-acetyl-alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6-tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant.

228405:HNE RS09230
gene id: 228405:HNE_RS09230
uniprot id: Q0C126
names: Similarity
messages: Belongs to the GSP E family.

228405:HNE RS03280
gene id: 228405:HNE_RS03280
uniprot id: Q0C4F7
names: Similarity
messages: Belongs to the peptidase C40 family.

228405:HNE RS11100
gene id: 228405:HNE_RS11100
uniprot id: Q0C004
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

228405:HNE RS00845
gene id: 228405:HNE_RS00845
uniprot id: Q0C5T9
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

228405:HNE RS03080
gene id: 228405:HNE_RS03080
uniprot id: Q0C4J6
names: Similarity
messages: Belongs to the aspartokinase family.

228405:HNE RS15320
gene id: 228405:HNE_RS15320
uniprot id: Q0BXM1
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

228405:HNE RS05215
gene id: 228405:HNE_RS05215
uniprot id: Q0C3B9
names: Function
names: Similarity
messages: Belongs to the peroxiredoxin family. Prx5 subfamily.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

228405:HNE RS14525
gene id: 228405:HNE_RS14525
uniprot id: Q0BY28
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

228405:HNE RS03845
gene id: 228405:HNE_RS03845
uniprot id: Q0C444
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

228405:HNE RS05130
gene id: 228405:HNE_RS05130
uniprot id: Q0C3D7
names: Similarity
messages: Belongs to the peptidase U62 family.

228405:HNE RS02005
gene id: 228405:HNE_RS02005
uniprot id: Q0C563
names: Subcellular Location Annotation
messages: Membrane

228405:HNE RS02820
gene id: 228405:HNE_RS02820
uniprot id: Q0C4P9
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

228405:HNE RS08465
gene id: 228405:HNE_RS08465
uniprot id: Q0C1H1
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

228405:HNE RS09335
gene id: 228405:HNE_RS09335
uniprot id: Q0C105
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

228405:HNE RS17505
gene id: 228405:HNE_RS17505
uniprot id: Q0BWD1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Essential cell division protein that coordinates cell division and chromosome segregation. The N-terminus is involved in assembly of the cell-division machinery. The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the dif recombination site, which is located within the replication terminus region. Translocation stops specifically at Xer-dif sites, where FtsK interacts with the Xer recombinase, allowing activation of chromosome unlinking by recombination. FtsK orienting polar sequences (KOPS) guide the direction of DNA translocation. FtsK can remove proteins from DNA as it translocates, but translocation stops specifically at XerCD-dif site, thereby preventing removal of XerC and XerD from dif.
messages: Homohexamer. Forms a ring that surrounds DNA.
messages: Membrane

228405:HNE RS07675
gene id: 228405:HNE_RS07675
uniprot id: Q0C1X9
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

228405:HNE RS08170
gene id: 228405:HNE_RS08170
uniprot id: Q0C1N1
names: Function
messages: Catalyzes the oxidation of D-lactate to pyruvate.

228405:HNE RS06505
gene id: 228405:HNE_RS06505
uniprot id: Q0C2L5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.
messages: Cell inner membrane
messages: Membrane

228405:HNE RS17345
gene id: 228405:HNE_RS17345
uniprot id: Q0BWG4
names: Similarity
messages: Belongs to the creatininase superfamily.

228405:HNE RS11125
gene id: 228405:HNE_RS11125
uniprot id: Q0BZZ9
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

228405:HNE RS13075
gene id: 228405:HNE_RS13075
uniprot id: Q0BYV9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

228405:HNE RS13720
gene id: 228405:HNE_RS13720
uniprot id: Q0BYJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

228405:HNE RS13190
gene id: 228405:HNE_RS13190
uniprot id: Q0BYU5
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

228405:HNE RS06845
gene id: 228405:HNE_RS06845
uniprot id: Q0C2E7
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

228405:HNE RS12385
gene id: 228405:HNE_RS12385
uniprot id: Q0BZ92
names: Function
messages: Acts on leucine, isoleucine and valine.

228405:HNE RS02340
gene id: 228405:HNE_RS02340
uniprot id: Q0C4Z4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the band 7/mec-2 family. HflK subfamily.
messages: HflC and HflK could encode or regulate a protease.
messages: HflC and HflK may interact to form a multimeric complex.
messages: Membrane

228405:HNE RS12155
gene id: 228405:HNE_RS12155
uniprot id: Q0BZD9
names: Similarity
messages: Belongs to the phosphate/phosphite/phosphonate binding protein family.

228405:HNE RS08750
gene id: 228405:HNE_RS08750
uniprot id: Q0C1B7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

228405:HNE RS00355
gene id: 228405:HNE_RS00355
uniprot id: Q0C638
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

228405:HNE RS00135
gene id: 228405:HNE_RS00135
uniprot id: Q0C682
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

228405:HNE RS10370
gene id: 228405:HNE_RS10370
uniprot id: Q0C0F1
names: Similarity
messages: Belongs to the CobT family.

228405:HNE RS11845
gene id: 228405:HNE_RS11845
uniprot id: Q0BZK2
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAL/histidase family.
messages: Contains an active site 4-methylidene-imidazol-5-one (MIO), which is formed autocatalytically by cyclization and dehydration of residues Ala-Ser-Gly.
messages: Cytoplasm

228405:HNE RS06300
gene id: 228405:HNE_RS06300
uniprot id: Q0C2Q5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

228405:HNE RS05695
gene id: 228405:HNE_RS05695
uniprot id: Q0C327
names: Similarity
messages: Belongs to the UDPGP type 2 family.

228405:HNE RS02825
gene id: 228405:HNE_RS02825
uniprot id: Q0C4P8
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

228405:HNE RS14730
gene id: 228405:HNE_RS14730
uniprot id: Q0BXY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

228405:HNE RS08740
gene id: 228405:HNE_RS08740
uniprot id: Q0C1B9
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.

228405:HNE RS02940
gene id: 228405:HNE_RS02940
uniprot id: Q0C4M3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

228405:HNE RS04235
gene id: 228405:HNE_RS04235
uniprot id: Q0C3W6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell inner membrane
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

228405:HNE RS14910
gene id: 228405:HNE_RS14910
uniprot id: Q0BXV2
names: Similarity
messages: Belongs to the bacterial secretin family.

228405:HNE RS04695
gene id: 228405:HNE_RS04695
uniprot id: Q0C3M3
names: Similarity
messages: Belongs to the ParA family. MinD subfamily.

228405:HNE RS02245
gene id: 228405:HNE_RS02245
uniprot id: Q0C514
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

228405:HNE RS11375
gene id: 228405:HNE_RS11375
uniprot id: Q0BZU6
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

228405:HNE RS11225
gene id: 228405:HNE_RS11225
uniprot id: Q0BZX9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

228405:HNE RS07685
gene id: 228405:HNE_RS07685
uniprot id: Q0C1X7
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

228405:HNE RS11770
gene id: 228405:HNE_RS11770
uniprot id: Q0BZL7
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.

228405:HNE RS04480
gene id: 228405:HNE_RS04480
uniprot id: Q0C3R6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

228405:HNE RS13630
gene id: 228405:HNE_RS13630
uniprot id: Q0BYK9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

228405:HNE RS16000
gene id: 228405:HNE_RS16000
uniprot id: Q0BX85
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 3B subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

228405:HNE RS04080
gene id: 228405:HNE_RS04080
uniprot id: Q0C3Z8
names: Similarity
messages: Belongs to the TlyA family.

228405:HNE RS13865
gene id: 228405:HNE_RS13865
uniprot id: Q0BYG1
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

228405:HNE RS12020
gene id: 228405:HNE_RS12020
uniprot id: Q0BZG6
names: Subcellular Location Annotation
messages: Membrane

228405:HNE RS01230
gene id: 228405:HNE_RS01230
uniprot id: Q0C5L4
names: Similarity
messages: Belongs to the bacterial flagellin family.

228405:HNE RS10480
gene id: 228405:HNE_RS10480
uniprot id: Q0C0C8
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

228405:HNE RS05735
gene id: 228405:HNE_RS05735
uniprot id: Q0C319
names: Subcellular Location Annotation
messages: Membrane

228405:HNE RS11635
gene id: 228405:HNE_RS11635
uniprot id: Q0BZP4
names: Similarity
messages: Belongs to the GST superfamily. NadH family.

228405:HNE RS09710
gene id: 228405:HNE_RS09710
uniprot id: Q0C0T0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

228405:HNE RS12750
gene id: 228405:HNE_RS12750
uniprot id: Q0BZ24
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Monomer.

228405:HNE RS06920
gene id: 228405:HNE_RS06920
uniprot id: Q0C2D2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliN/MopA/SpaO family.
messages: Cell membrane
messages: FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

228405:HNE RS15230
gene id: 228405:HNE_RS15230
uniprot id: Q0BXN7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

228405:HNE RS13310
gene id: 228405:HNE_RS13310
uniprot id: Q0BYS3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

228405:HNE RS09675
gene id: 228405:HNE_RS09675
uniprot id: Q0C0T7
names: Similarity
messages: Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.

228405:HNE RS02945
gene id: 228405:HNE_RS02945
uniprot id: Q0C4M2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm
messages: Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.

228405:HNE RS02700
gene id: 228405:HNE_RS02700
uniprot id: Q0C4S2
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

228405:HNE RS10405
gene id: 228405:HNE_RS10405
uniprot id: Q0C0E3
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

228405:HNE RS10390
gene id: 228405:HNE_RS10390
uniprot id: Q0C0E6
names: Domain
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
messages: Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.

228405:HNE RS13535
gene id: 228405:HNE_RS13535
uniprot id: Q0BYM7
names: Similarity
messages: Belongs to the universal stress protein A family.

228405:HNE RS04440
gene id: 228405:HNE_RS04440
uniprot id: Q0C3S4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial solute-binding protein 7 family.
messages: Homodimer.
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: Periplasm

228405:HNE RS04020
gene id: 228405:HNE_RS04020
uniprot id: Q0C410
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

228405:HNE RS08995
gene id: 228405:HNE_RS08995
uniprot id: Q0C171
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

228405:HNE RS00840
gene id: 228405:HNE_RS00840
uniprot id: Q0C5U0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inositol monophosphatase superfamily. CysQ family.
messages: Cell inner membrane
messages: Converts adenosine-3',5'-bisphosphate (PAP) to AMP.

228405:HNE RS00550
gene id: 228405:HNE_RS00550
uniprot id: Q0C5Z8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

228405:HNE RS04870
gene id: 228405:HNE_RS04870
uniprot id: Q0C3I8
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

228405:HNE RS11975
gene id: 228405:HNE_RS11975
uniprot id: Q0BZH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

228405:HNE RS13600
gene id: 228405:HNE_RS13600
uniprot id: Q0BYL5
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

228405:HNE RS01860
gene id: 228405:HNE_RS01860
uniprot id: Q0C592
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

228405:HNE RS00635
gene id: 228405:HNE_RS00635
uniprot id: Q0C5Y1
names: Similarity
messages: Belongs to the OMP decarboxylase family. Type 2 subfamily.

228405:HNE RS13430
gene id: 228405:HNE_RS13430
uniprot id: Q0BYP8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

228405:HNE RS00240
gene id: 228405:HNE_RS00240
uniprot id: Q0C661
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

228405:HNE RS08530
gene id: 228405:HNE_RS08530
uniprot id: Q0C1F9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

228405:HNE RS12605
gene id: 228405:HNE_RS12605
uniprot id: Q0BZ49
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

228405:HNE RS16880
gene id: 228405:HNE_RS16880
uniprot id: Q0BWQ7
names: Similarity
messages: Belongs to the tRNA methyltransferase O family.

228405:HNE RS04520
gene id: 228405:HNE_RS04520
uniprot id: Q0C3Q8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

228405:HNE RS15960
gene id: 228405:HNE_RS15960
uniprot id: Q0BX92
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

228405:HNE RS10325
gene id: 228405:HNE_RS10325
uniprot id: Q0C0G0
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

228405:HNE RS08165
gene id: 228405:HNE_RS08165
uniprot id: Q0C1N2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

228405:HNE RS05645
gene id: 228405:HNE_RS05645
uniprot id: Q0C337
names: Similarity
messages: Belongs to the peptidase S66 family.

228405:HNE RS01690
gene id: 228405:HNE_RS01690
uniprot id: Q0C5C6
names: Subcellular Location Annotation
messages: Membrane

228405:HNE RS08600
gene id: 228405:HNE_RS08600
uniprot id: Q0C1E7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell inner membrane
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

228405:HNE RS17020
gene id: 228405:HNE_RS17020
uniprot id: Q0BWM8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

228405:HNE RS11250
gene id: 228405:HNE_RS11250
uniprot id: Q0BZX4
names: Subcellular Location Annotation
messages: Membrane

228405:HNE RS02160
gene id: 228405:HNE_RS02160
uniprot id: Q0C532
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

228405:HNE RS08920
gene id: 228405:HNE_RS08920
uniprot id: Q0C183
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

228405:HNE RS13350
gene id: 228405:HNE_RS13350
uniprot id: Q0BYR5
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily.

228405:HNE RS11360
gene id: 228405:HNE_RS11360
uniprot id: Q0BZU9
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

228405:HNE RS02315
gene id: 228405:HNE_RS02315
uniprot id: Q0C500
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

228405:HNE RS10190
gene id: 228405:HNE_RS10190
uniprot id: Q0C0I6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

228405:HNE RS04970
gene id: 228405:HNE_RS04970
uniprot id: Q0C3G8
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.

228405:HNE RS02080
gene id: 228405:HNE_RS02080
uniprot id: Q0C548
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

228405:HNE RS00015
gene id: 228405:HNE_RS00015
uniprot id: Q0C6A6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).

228405:HNE RS08955
gene id: 228405:HNE_RS08955
uniprot id: Q0C176
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

228405:HNE RS01535
gene id: 228405:HNE_RS01535
uniprot id: Q0C5F9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

228405:HNE RS04900
gene id: 228405:HNE_RS04900
uniprot id: Q0C3I2
names: Similarity
messages: Belongs to the GST superfamily. NadH family.

228405:HNE RS18625
gene id: 228405:HNE_RS18625
uniprot id: Q0BX77
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b560 family.
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD. The complex can form homotrimers.
messages: The heme is bound between the two transmembrane subunits.

228405:HNE RS15860
gene id: 228405:HNE_RS15860
uniprot id: Q0BXB1
names: Function
names: Similarity
messages: Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
messages: Belongs to the Nudix hydrolase family. RppH subfamily.

228405:HNE RS05180
gene id: 228405:HNE_RS05180
uniprot id: Q0C3C6
names: Similarity
messages: Belongs to the threonine synthase family.

228405:HNE RS09500
gene id: 228405:HNE_RS09500
uniprot id: Q0C0X2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase C chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.

228405:HNE RS02270
gene id: 228405:HNE_RS02270
uniprot id: Q0C509
names: Similarity
messages: Belongs to the Nudix hydrolase family.

228405:HNE RS08295
gene id: 228405:HNE_RS08295
uniprot id: Q0C1K6
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

228405:HNE RS02550
gene id: 228405:HNE_RS02550
uniprot id: Q0C4V2
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

228405:HNE RS13695
gene id: 228405:HNE_RS13695
uniprot id: Q0BYJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmG family. TrmFO subfamily.
messages: Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
messages: Cytoplasm

228405:HNE RS10475
gene id: 228405:HNE_RS10475
uniprot id: Q0C0C9
names: Cofactor
messages: Binds 1 Fe(2+) ion per subunit.

228405:HNE RS08340
gene id: 228405:HNE_RS08340
uniprot id: Q0C1J8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MerT family.
messages: Cell inner membrane
messages: Membrane

228405:HNE RS08865
gene id: 228405:HNE_RS08865
uniprot id: Q0C194
names: Similarity
messages: Belongs to the CFA/CMAS family.

228405:HNE RS05585
gene id: 228405:HNE_RS05585
uniprot id: Q0C347
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

228405:HNE RS03335
gene id: 228405:HNE_RS03335
uniprot id: Q0C4E6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

228405:HNE RS14055
gene id: 228405:HNE_RS14055
uniprot id: Q0BYC5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

228405:HNE RS09905
gene id: 228405:HNE_RS09905
uniprot id: Q0C0P3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell inner membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

228405:HNE RS09760
gene id: 228405:HNE_RS09760
uniprot id: Q0C0S1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

228405:HNE RS10040
gene id: 228405:HNE_RS10040
uniprot id: Q0C0L6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

228405:HNE RS13020
gene id: 228405:HNE_RS13020
uniprot id: Q0BYW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

228405:HNE RS08360
gene id: 228405:HNE_RS08360
uniprot id: Q0C1J4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

228405:HNE RS08900
gene id: 228405:HNE_RS08900
uniprot id: Q0C187
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
messages: Cytoplasm
messages: Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.

228405:HNE RS08780
gene id: 228405:HNE_RS08780
uniprot id: Q0C1B1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

228405:HNE RS16235
gene id: 228405:HNE_RS16235
uniprot id: Q0BX38
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

228405:HNE RS10625
gene id: 228405:HNE_RS10625
uniprot id: Q0C098
names: Similarity
messages: Belongs to the DprA/Smf family.

228405:HNE RS09365
gene id: 228405:HNE_RS09365
uniprot id: Q0C0Z9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

228405:HNE RS08490
gene id: 228405:HNE_RS08490
uniprot id: Q0C1G7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TrbI/VirB10 family.
messages: Membrane

228405:HNE RS14890
gene id: 228405:HNE_RS14890
uniprot id: Q0BXV6
names: Subcellular Location Annotation
messages: Membrane

228405:HNE RS10045
gene id: 228405:HNE_RS10045
uniprot id: Q0C0L5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.
messages: Cell inner membrane
messages: Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

228405:HNE RS02975
gene id: 228405:HNE_RS02975
uniprot id: Q0C4L6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Cell inner membrane
messages: Homoheptamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.
messages: Membrane

228405:HNE RS13895
gene id: 228405:HNE_RS13895
uniprot id: Q0BYF4
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

228405:HNE RS17340
gene id: 228405:HNE_RS17340
uniprot id: Q0BWG5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.

228405:HNE RS10295
gene id: 228405:HNE_RS10295
uniprot id: Q0C0G6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

228405:HNE RS10845
gene id: 228405:HNE_RS10845
uniprot id: Q0C053
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.

228405:HNE RS13675
gene id: 228405:HNE_RS13675
uniprot id: Q0BYK0
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

228405:HNE RS15270
gene id: 228405:HNE_RS15270
uniprot id: Q0BXN0
names: Subcellular Location Annotation
messages: Membrane

228405:HNE RS06680
gene id: 228405:HNE_RS06680
uniprot id: Q0C2I0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

228405:HNE RS17385
gene id: 228405:HNE_RS17385
uniprot id: Q0BWF6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmB/CycW/HelB family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

228405:HNE RS12165
gene id: 228405:HNE_RS12165
uniprot id: Q0BZD7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

228405:HNE RS09705
gene id: 228405:HNE_RS09705
uniprot id: Q0C0T1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

228405:HNE RS10250
gene id: 228405:HNE_RS10250
uniprot id: Q0C0H4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

228405:HNE RS07695
gene id: 228405:HNE_RS07695
uniprot id: Q0C1X5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

228405:HNE RS11090
gene id: 228405:HNE_RS11090
uniprot id: Q0C006
names: Similarity
messages: Belongs to the iron/ascorbate-dependent oxidoreductase family.

228405:HNE RS05750
gene id: 228405:HNE_RS05750
uniprot id: Q0C316
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-insensitive subfamily.
messages: Cell inner membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force.

228405:HNE RS15920
gene id: 228405:HNE_RS15920
uniprot id: Q0BX99
names: Subcellular Location Annotation
messages: Membrane

228405:HNE RS14050
gene id: 228405:HNE_RS14050
uniprot id: Q0BYC6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

228405:HNE RS16190
gene id: 228405:HNE_RS16190
uniprot id: Q0BX47
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).

228405:HNE RS02610
gene id: 228405:HNE_RS02610
uniprot id: Q0C4U0
names: Similarity
messages: Belongs to the nitroreductase family. HadB/RutE subfamily.

228405:HNE RS11295
gene id: 228405:HNE_RS11295
uniprot id: Q0BZW4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

228405:HNE RS02655
gene id: 228405:HNE_RS02655
uniprot id: Q0C4T1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.

228405:HNE RS01270
gene id: 228405:HNE_RS01270
uniprot id: Q0C5K6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

228405:HNE RS10620
gene id: 228405:HNE_RS10620
uniprot id: Q0C099
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell inner membrane
messages: Probably interacts with PlsX.

228405:HNE RS03385
gene id: 228405:HNE_RS03385
uniprot id: Q0C4D6
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

228405:HNE RS03520
gene id: 228405:HNE_RS03520
uniprot id: Q0C4B0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.

228405:HNE RS10650
gene id: 228405:HNE_RS10650
uniprot id: Q0C093
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

228405:HNE RS16165
gene id: 228405:HNE_RS16165
uniprot id: Q0BX53
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

228405:HNE RS17525
gene id: 228405:HNE_RS17525
uniprot id: Q0BWC7
names: Similarity
messages: Belongs to the UPF0434 family.

228405:HNE RS09225
gene id: 228405:HNE_RS09225
uniprot id: Q0C127
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial secretin family. GSP D subfamily.
messages: Cell outer membrane

228405:HNE RS01290
gene id: 228405:HNE_RS01290
uniprot id: Q0C5K2
names: Function
names: Similarity
messages: Belongs to the FlgD family.
messages: Required for flagellar hook formation. May act as a scaffolding protein.

228405:HNE RS13910
gene id: 228405:HNE_RS13910
uniprot id: Q0BYF1
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.

228405:HNE RS10685
gene id: 228405:HNE_RS10685
uniprot id: Q0C085
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

228405:HNE RS16495
gene id: 228405:HNE_RS16495
uniprot id: Q0BWY5
names: Similarity
messages: Belongs to the ArsC family.

228405:HNE RS06935
gene id: 228405:HNE_RS06935
uniprot id: Q0C2C9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

228405:HNE RS07270
gene id: 228405:HNE_RS07270
uniprot id: Q0C261
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

228405:HNE RS16005
gene id: 228405:HNE_RS16005
uniprot id: Q0BX84
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

228405:HNE RS04705
gene id: 228405:HNE_RS04705
uniprot id: Q0C3M1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

228405:HNE RS05200
gene id: 228405:HNE_RS05200
uniprot id: Q0C3C2
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

228405:HNE RS15835
gene id: 228405:HNE_RS15835
uniprot id: Q0BXB7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

228405:HNE RS02795
gene id: 228405:HNE_RS02795
uniprot id: Q0C4Q4
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.

228405:HNE RS02755
gene id: 228405:HNE_RS02755
uniprot id: Q0C4R2
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

228405:HNE RS10670
gene id: 228405:HNE_RS10670
uniprot id: Q0C089
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

228405:HNE RS02595
gene id: 228405:HNE_RS02595
uniprot id: Q0C4U3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.

228405:HNE RS13365
gene id: 228405:HNE_RS13365
uniprot id: Q0BYR2
names: Similarity
messages: Belongs to the Nudix hydrolase family.

228405:HNE RS14920
gene id: 228405:HNE_RS14920
uniprot id: Q0BXV0
names: Similarity
messages: Belongs to the peptidase A24 family.

228405:HNE RS14040
gene id: 228405:HNE_RS14040
uniprot id: Q0BYC8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

228405:HNE RS06840
gene id: 228405:HNE_RS06840
uniprot id: Q0C2E8
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

228405:HNE RS11725
gene id: 228405:HNE_RS11725
uniprot id: Q0BZM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

228405:HNE RS15840
gene id: 228405:HNE_RS15840
uniprot id: Q0BXB5
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Toroid-shaped homodecamer, composed of two pentamers of five dimers.

228405:HNE RS01960
gene id: 228405:HNE_RS01960
uniprot id: Q0C572
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Belongs to the heat shock protein 70 family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell inner membrane
messages: Self-interacts. Interacts with FtsZ.

228405:HNE RS11435
gene id: 228405:HNE_RS11435
uniprot id: Q0BZT5
names: Subcellular Location Annotation
messages: Cytoplasm

228405:HNE RS13205
gene id: 228405:HNE_RS13205
uniprot id: Q0BYU2
names: Similarity
messages: Belongs to the PhoH family.

228405:HNE RS06865
gene id: 228405:HNE_RS06865
uniprot id: Q0C2E3
names: Subcellular Location Annotation
messages: Mitochondrion

228405:HNE RS14065
gene id: 228405:HNE_RS14065
uniprot id: Q0BYC3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

228405:HNE RS14115
gene id: 228405:HNE_RS14115
uniprot id: Q0BYB3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

228405:HNE RS15025
gene id: 228405:HNE_RS15025
uniprot id: Q0BXS9
names: Subcellular Location Annotation
messages: Membrane

228405:HNE RS03930
gene id: 228405:HNE_RS03930
uniprot id: Q0C427
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

228405:HNE RS09550
gene id: 228405:HNE_RS09550
uniprot id: Q0C0W2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.

228405:HNE RS02215
gene id: 228405:HNE_RS02215
uniprot id: Q0C520
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the hcp beta-lactamase family.
messages: Hydrolyzes 6-aminopenicillinic acid and 7-aminocephalosporanic acid (ACA) derivatives.
messages: Secreted

228405:HNE RS02050
gene id: 228405:HNE_RS02050
uniprot id: Q0C554
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Membrane

228405:HNE RS06770
gene id: 228405:HNE_RS06770
uniprot id: Q0C2G2
names: Similarity
messages: Belongs to the peptidase U62 family.

228405:HNE RS08395
gene id: 228405:HNE_RS08395
uniprot id: Q0C1I7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

228405:HNE RS09270
gene id: 228405:HNE_RS09270
uniprot id: Q0C118
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP M family.
messages: Cell inner membrane
messages: Membrane

228405:HNE RS01565
gene id: 228405:HNE_RS01565
uniprot id: Q0C5F3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

228405:HNE RS02875
gene id: 228405:HNE_RS02875
uniprot id: Q0C4N7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

228405:HNE RS13900
gene id: 228405:HNE_RS13900
uniprot id: Q0BYF3
names: Similarity
messages: Belongs to the thioesterase PaaI family.

228405:HNE RS08720
gene id: 228405:HNE_RS08720
uniprot id: Q0C1C3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3.A.1.125) family.
messages: Cell inner membrane
messages: Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.
messages: The complex is composed of two ATP-binding proteins (LolD) and two transmembrane proteins (LolC and LolE).

228405:HNE RS01350
gene id: 228405:HNE_RS01350
uniprot id: Q0C5J0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Membrane

228405:HNE RS02455
gene id: 228405:HNE_RS02455
uniprot id: Q0C4X1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. TCR/Tet family.
messages: Membrane
messages: Resistance to tetracycline by an active tetracycline efflux. This is an energy-dependent process that decreases the accumulation of the antibiotic in whole cells. This protein functions as a metal-tetracycline/H(+) antiporter.

228405:HNE RS09630
gene id: 228405:HNE_RS09630
uniprot id: Q0C0U6
names: Similarity
messages: Belongs to the BolA/IbaG family.

228405:HNE RS03590
gene id: 228405:HNE_RS03590
uniprot id: Q0C496
names: Subcellular Location Annotation
messages: Membrane

228405:HNE RS01900
gene id: 228405:HNE_RS01900
uniprot id: Q0C584
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

228405:HNE RS16690
gene id: 228405:HNE_RS16690
uniprot id: Q0BWU4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRA-CH family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
messages: Cytoplasm
messages: Homodimer.

228405:HNE RS14170
gene id: 228405:HNE_RS14170
uniprot id: Q0BYA1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

228405:HNE RS03765
gene id: 228405:HNE_RS03765
uniprot id: Q0C460
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

228405:HNE RS17215
gene id: 228405:HNE_RS17215
uniprot id: Q0BWJ1
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

228405:HNE RS02205
gene id: 228405:HNE_RS02205
uniprot id: Q0C522
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Membrane

228405:HNE RS05890
gene id: 228405:HNE_RS05890
uniprot id: Q0C2Y7
names: Subcellular Location Annotation
messages: Membrane

228405:HNE RS06630
gene id: 228405:HNE_RS06630
uniprot id: Q0C2J0
names: Similarity
messages: Belongs to the FGGY kinase family.

228405:HNE RS00305
gene id: 228405:HNE_RS00305
uniprot id: Q0C648
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

228405:HNE RS06545
gene id: 228405:HNE_RS06545
uniprot id: Q0C2K7
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

228405:HNE RS14135
gene id: 228405:HNE_RS14135
uniprot id: Q0BYA9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

228405:HNE RS09380
gene id: 228405:HNE_RS09380
uniprot id: Q0C0Z6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

228405:HNE RS12895
gene id: 228405:HNE_RS12895
uniprot id: Q0BYZ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

228405:HNE RS12710
gene id: 228405:HNE_RS12710
uniprot id: Q0BZ30
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

228405:HNE RS05030
gene id: 228405:HNE_RS05030
uniprot id: Q0C3F6
names: Similarity
messages: Belongs to the GST superfamily.

228405:HNE RS13995
gene id: 228405:HNE_RS13995
uniprot id: Q0BYD7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

228405:HNE RS04845
gene id: 228405:HNE_RS04845
uniprot id: Q0C3J2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family. ParE type 1 subfamily.
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

228405:HNE RS08280
gene id: 228405:HNE_RS08280
uniprot id: Q0C1K9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

228405:HNE RS09085
gene id: 228405:HNE_RS09085
uniprot id: Q0C154
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

228405:HNE RS02180
gene id: 228405:HNE_RS02180
uniprot id: Q0C527
names: Subcellular Location Annotation
messages: Membrane

228405:HNE RS12065
gene id: 228405:HNE_RS12065
uniprot id: Q0BZF7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

228405:HNE RS13160
gene id: 228405:HNE_RS13160
uniprot id: Q0BYV0
names: Subcellular Location Annotation
messages: Membrane

228405:HNE RS08825
gene id: 228405:HNE_RS08825
uniprot id: Q0C1A2
names: Similarity
messages: Belongs to the TrpC family.

228405:HNE RS00455
gene id: 228405:HNE_RS00455
uniprot id: Q0C618
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell inner membrane

228405:HNE RS00155
gene id: 228405:HNE_RS00155
uniprot id: Q0C678
names: Function
names: Similarity
names: Subunit
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Homodimer.

228405:HNE RS01570
gene id: 228405:HNE_RS01570
uniprot id: Q0C5F2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

228405:HNE RS17070
gene id: 228405:HNE_RS17070
uniprot id: Q0BWL8
names: Similarity
messages: Belongs to the citrate synthase family.

228405:HNE RS11095
gene id: 228405:HNE_RS11095
uniprot id: Q0C005
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

228405:HNE RS07375
gene id: 228405:HNE_RS07375
uniprot id: Q0C239
names: Subcellular Location Annotation
messages: Membrane

228405:HNE RS14030
gene id: 228405:HNE_RS14030
uniprot id: Q0BYD0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

228405:HNE RS15950
gene id: 228405:HNE_RS15950
uniprot id: Q0BX94
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

228405:HNE RS08585
gene id: 228405:HNE_RS08585
uniprot id: Q0C1F0
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

228405:HNE RS09875
gene id: 228405:HNE_RS09875
uniprot id: Q0C0P8
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

228405:HNE RS05680
gene id: 228405:HNE_RS05680
uniprot id: Q0C330
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

228405:HNE RS10330
gene id: 228405:HNE_RS10330
uniprot id: Q0C0F9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

228405:HNE RS01030
gene id: 228405:HNE_RS01030
uniprot id: Q0C5Q3
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

228405:HNE RS12665
gene id: 228405:HNE_RS12665
uniprot id: Q0BZ39
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

228405:HNE RS04310
gene id: 228405:HNE_RS04310
uniprot id: Q0C3V0
names: Similarity
messages: Belongs to the peptidase S9C family.

228405:HNE RS08095
gene id: 228405:HNE_RS08095
uniprot id: Q0C1P5
names: Function
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
messages: Catalyzes reversively the conversion of L-aspartate beta-semialdehyde (ASA) to L-2,4-diaminobutyrate (DABA) by transamination with L-glutamate.

228405:HNE RS11575
gene id: 228405:HNE_RS11575
uniprot id: Q0BZQ8
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

228405:HNE RS05530
gene id: 228405:HNE_RS05530
uniprot id: Q0C357
names: Function
names: Similarity
messages: Belongs to the polysaccharide deacetylase family.
messages: Is involved in generating a small heat-stable compound (Nod), an acylated oligomer of N-acetylglucosamine, that stimulates mitosis in various plant protoplasts.

228405:HNE RS09245
gene id: 228405:HNE_RS09245
uniprot id: Q0C123
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP H family.
messages: Cell inner membrane
messages: Membrane

228405:HNE RS07770
gene id: 228405:HNE_RS07770
uniprot id: Q0C1W0
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

228405:HNE RS15005
gene id: 228405:HNE_RS15005
uniprot id: Q0BXT3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

228405:HNE RS16985
gene id: 228405:HNE_RS16985
uniprot id: Q0BWN5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thioester dehydratase family. FabA subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP. Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length.

228405:HNE RS08450
gene id: 228405:HNE_RS08450
uniprot id: Q0C1H4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

228405:HNE RS10315
gene id: 228405:HNE_RS10315
uniprot id: Q0C0G2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glutamine synthetase family.
messages: Catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia.
messages: Cytoplasm
messages: Oligomer of 12 subunits arranged in the form of two hexagons.
messages: Oligomer of 12 subunits arranged in the form of two hexameric ring.

228405:HNE RS02760
gene id: 228405:HNE_RS02760
uniprot id: Q0C4R1
names: Similarity
messages: Belongs to the DEAD box helicase family.

228405:HNE RS03955
gene id: 228405:HNE_RS03955
uniprot id: Q0C422
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.
messages: Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

228405:HNE RS16170
gene id: 228405:HNE_RS16170
uniprot id: Q0BX52
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

228405:HNE RS09570
gene id: 228405:HNE_RS09570
uniprot id: Q0C0V8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell inner membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

228405:HNE RS05920
gene id: 228405:HNE_RS05920
uniprot id: Q0C2Y1
names: Subcellular Location Annotation
messages: Membrane

228405:HNE RS10145
gene id: 228405:HNE_RS10145
uniprot id: Q0C0J5
names: Similarity
messages: Belongs to the dGTPase family. Type 2 subfamily.

228405:HNE RS16360
gene id: 228405:HNE_RS16360
uniprot id: Q0BX12
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

228405:HNE RS08655
gene id: 228405:HNE_RS08655
uniprot id: Q0C1D6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

228405:HNE RS15355
gene id: 228405:HNE_RS15355
uniprot id: Q0BXL4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueG family.
messages: Binds 2 [4Fe-4S] clusters per monomer.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

228405:HNE RS03595
gene id: 228405:HNE_RS03595
uniprot id: Q0C495
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

228405:HNE RS08855
gene id: 228405:HNE_RS08855
uniprot id: Q0C196
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

228405:HNE RS08745
gene id: 228405:HNE_RS08745
uniprot id: Q0C1B8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

228405:HNE RS14780
gene id: 228405:HNE_RS14780
uniprot id: Q0BXX8
names: Function
names: Similarity
messages: In the C-terminal section; belongs to the aldehyde dehydrogenase family.
messages: In the N-terminal section; belongs to the proline dehydrogenase family.
messages: Oxidizes proline to glutamate for use as a carbon and nitrogen source.

228405:HNE RS02335
gene id: 228405:HNE_RS02335
uniprot id: Q0C4Z5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

228405:HNE RS04715
gene id: 228405:HNE_RS04715
uniprot id: Q0C3L9
names: Similarity
messages: Belongs to the pseudomonas-type ThrB family.

228405:HNE RS15505
gene id: 228405:HNE_RS15505
uniprot id: Q0BXI4
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

228405:HNE RS17300
gene id: 228405:HNE_RS17300
uniprot id: Q0BWH4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

228405:HNE RS02860
gene id: 228405:HNE_RS02860
uniprot id: Q0C4P1
names: Similarity
messages: Belongs to the thioesterase PaaI family.

228405:HNE RS15700
gene id: 228405:HNE_RS15700
uniprot id: Q0BXE4
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

228405:HNE RS04430
gene id: 228405:HNE_RS04430
uniprot id: Q0C3S6
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.

228405:HNE RS10725
gene id: 228405:HNE_RS10725
uniprot id: Q0C077
names: Function
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.

228405:HNE RS15540
gene id: 228405:HNE_RS15540
uniprot id: Q0BXH7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

228405:HNE RS08525
gene id: 228405:HNE_RS08525
uniprot id: Q0C1G0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family.
messages: Membrane

228405:HNE RS11260
gene id: 228405:HNE_RS11260
uniprot id: Q0BZX2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

228405:HNE RS01380
gene id: 228405:HNE_RS01380
uniprot id: Q0C5I4
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

228405:HNE RS18950
gene id: 228405:HNE_RS18950
uniprot id: Q0C0V9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatB family.
messages: Cell inner membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

228405:HNE RS02015
gene id: 228405:HNE_RS02015
uniprot id: Q0C561
names: Similarity
messages: Belongs to the peptidase S13 family.

228405:HNE RS17105
gene id: 228405:HNE_RS17105
uniprot id: Q0BWL1
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

228405:HNE RS02810
gene id: 228405:HNE_RS02810
uniprot id: Q0C4Q1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

228405:HNE RS15190
gene id: 228405:HNE_RS15190
uniprot id: Q0BXP5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

228405:HNE RS15585
gene id: 228405:HNE_RS15585
uniprot id: Q0BXG9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.

228405:HNE RS00400
gene id: 228405:HNE_RS00400
uniprot id: Q0C629
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

228405:HNE RS08885
gene id: 228405:HNE_RS08885
uniprot id: Q0C190
names: Function
names: Similarity
names: Subunit
messages: Catalyzes the ADP transfer from ATP to D-glycero-beta-D-manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose.
messages: Catalyzes the phosphorylation of D-glycero-D-manno-heptose 7-phosphate at the C-1 position to selectively form D-glycero-beta-D-manno-heptose-1,7-bisphosphate.
messages: Homodimer.
messages: In the C-terminal section; belongs to the cytidylyltransferase family.
messages: In the N-terminal section; belongs to the carbohydrate kinase PfkB family.

228405:HNE RS10485
gene id: 228405:HNE_RS10485
uniprot id: Q0C0C7
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

228405:HNE RS06095
gene id: 228405:HNE_RS06095
uniprot id: Q0C2U6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CcoP / FixP family.
messages: Binds 2 heme C groups per subunit.
messages: C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex.
messages: Cell inner membrane
messages: Component of the cbb3-type cytochrome c oxidase.
messages: Membrane

228405:HNE RS10710
gene id: 228405:HNE_RS10710
uniprot id: Q0C080
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

228405:HNE RS04580
gene id: 228405:HNE_RS04580
uniprot id: Q0C3P7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the hcp beta-lactamase family.
messages: Hydrolyzes 6-aminopenicillinic acid and 7-aminocephalosporanic acid (ACA) derivatives.
messages: Secreted

228405:HNE RS00835
gene id: 228405:HNE_RS00835
uniprot id: Q0C5U1
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

228405:HNE RS05865
gene id: 228405:HNE_RS05865
uniprot id: Q0C2Z2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

228405:HNE RS08860
gene id: 228405:HNE_RS08860
uniprot id: Q0C195
names: Activity Regulation
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.

228405:HNE RS03350
gene id: 228405:HNE_RS03350
uniprot id: Q0C4E3
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

228405:HNE RS11365
gene id: 228405:HNE_RS11365
uniprot id: Q0BZU8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF nuclease family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

228405:HNE RS13110
gene id: 228405:HNE_RS13110
uniprot id: Q0BYV2
names: Similarity
messages: Belongs to the peptidase A24 family.

228405:HNE RS08580
gene id: 228405:HNE_RS08580
uniprot id: Q0C1F1
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

228405:HNE RS15080
gene id: 228405:HNE_RS15080
uniprot id: Q0BXR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

228405:HNE RS03965
gene id: 228405:HNE_RS03965
uniprot id: Q0C420
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

228405:HNE RS09740
gene id: 228405:HNE_RS09740
uniprot id: Q0C0S5
names: Similarity
messages: Belongs to the RecJ family.

228405:HNE RS08130
gene id: 228405:HNE_RS08130
uniprot id: Q0C1N8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Macrolide exporter (TC 3.A.1.122) family.
messages: Cell inner membrane
messages: Homodimer.
messages: Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.

228405:HNE RS06670
gene id: 228405:HNE_RS06670
uniprot id: Q0C2I2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm

228405:HNE RS03710
gene id: 228405:HNE_RS03710
uniprot id: Q0C471
names: Similarity
messages: Belongs to the SufE family.

228405:HNE RS04350
gene id: 228405:HNE_RS04350
uniprot id: Q0C3U2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.

228405:HNE RS08840
gene id: 228405:HNE_RS08840
uniprot id: Q0C199
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

228405:HNE RS04245
gene id: 228405:HNE_RS04245
uniprot id: Q0C3W4
names: Similarity
messages: Belongs to the peptidase M16 family.

228405:HNE RS11415
gene id: 228405:HNE_RS11415
uniprot id: Q0BZT8
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

228405:HNE RS12875
gene id: 228405:HNE_RS12875
uniprot id: Q0BYZ9
names: Similarity
messages: Belongs to the SAICAR synthetase family.

228405:HNE RS01815
gene id: 228405:HNE_RS01815
uniprot id: Q0C5A1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

228405:HNE RS05300
gene id: 228405:HNE_RS05300
uniprot id: Q0C3A3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

228405:HNE RS05345
gene id: 228405:HNE_RS05345
uniprot id: Q0C394
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

228405:HNE RS00755
gene id: 228405:HNE_RS00755
uniprot id: Q0C5V7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

228405:HNE RS05605
gene id: 228405:HNE_RS05605
uniprot id: Q0C343
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

228405:HNE RS14015
gene id: 228405:HNE_RS14015
uniprot id: Q0BYD3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

228405:HNE RS11165
gene id: 228405:HNE_RS11165
uniprot id: Q0BZZ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.

228405:HNE RS03465
gene id: 228405:HNE_RS03465
uniprot id: Q0C4B9
names: Similarity
messages: Belongs to the DEAD box helicase family.

228405:HNE RS12435
gene id: 228405:HNE_RS12435
uniprot id: Q0BZ82
names: Similarity
messages: Belongs to the GSP E family.

228405:HNE RS00180
gene id: 228405:HNE_RS00180
uniprot id: Q0C673
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Cell inner membrane
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

228405:HNE RS01825
gene id: 228405:HNE_RS01825
uniprot id: Q0C599
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

228405:HNE RS06355
gene id: 228405:HNE_RS06355
uniprot id: Q0C2P3
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

228405:HNE RS05450
gene id: 228405:HNE_RS05450
uniprot id: Q0C373
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

228405:HNE RS09120
gene id: 228405:HNE_RS09120
uniprot id: Q0C147
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

228405:HNE RS11900
gene id: 228405:HNE_RS11900
uniprot id: Q0BZJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

228405:HNE RS04345
gene id: 228405:HNE_RS04345
uniprot id: Q0C3U3
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

228405:HNE RS01480
gene id: 228405:HNE_RS01480
uniprot id: Q0C5H0
names: Function
names: Similarity
messages: Belongs to the Dus family. DusA subfamily.
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs.

228405:HNE RS17925
gene id: 228405:HNE_RS17925
uniprot id: Q0C1U7
names: Subcellular Location Annotation
messages: Membrane

228405:HNE RS04825
gene id: 228405:HNE_RS04825
uniprot id: Q0C3J7
names: Similarity
messages: Belongs to the AlaDH/PNT family.

228405:HNE RS16405
gene id: 228405:HNE_RS16405
uniprot id: Q0BX03
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

228405:HNE RS10150
gene id: 228405:HNE_RS10150
uniprot id: Q0C0J4
names: Similarity
messages: Belongs to the HesB/IscA family.

228405:HNE RS02385
gene id: 228405:HNE_RS02385
uniprot id: Q0C4Y4
names: Subcellular Location Annotation
messages: Membrane

228405:HNE RS17975
gene id: 228405:HNE_RS17975
uniprot id: Q0C174
names: Function
names: Similarity
messages: Belongs to the RlpA family.
messages: Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.

228405:HNE RS14885
gene id: 228405:HNE_RS14885
uniprot id: Q0BXV7
names: Subcellular Location Annotation
messages: Membrane

228405:HNE RS06855
gene id: 228405:HNE_RS06855
uniprot id: Q0C2E5
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: May be specifically involved in the processing, transport, and/or maturation of the MADH beta-subunit.
messages: Membrane

228405:HNE RS00120
gene id: 228405:HNE_RS00120
uniprot id: Q0C685
names: Similarity
messages: Belongs to the AHA1 family.

228405:HNE RS05490
gene id: 228405:HNE_RS05490
uniprot id: Q0C365
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

228405:HNE RS03905
gene id: 228405:HNE_RS03905
uniprot id: Q0C432
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

228405:HNE RS03200
gene id: 228405:HNE_RS03200
uniprot id: Q0C4H3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm

228405:HNE RS06860
gene id: 228405:HNE_RS06860
uniprot id: Q0C2E4
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

228405:HNE RS00660
gene id: 228405:HNE_RS00660
uniprot id: Q0C5X6
names: Similarity
messages: Belongs to the YciI family.

228405:HNE RS08545
gene id: 228405:HNE_RS08545
uniprot id: Q0C1F7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA gyrase inhibitor YacG family.
messages: Binds 1 zinc ion.
messages: Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.
messages: Interacts with GyrB.

228405:HNE RS09290
gene id: 228405:HNE_RS09290
uniprot id: Q0C114
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

228405:HNE RS02200
gene id: 228405:HNE_RS02200
uniprot id: Q0C523
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homotetramer.

228405:HNE RS16090
gene id: 228405:HNE_RS16090
uniprot id: Q0BX67
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

228405:HNE RS03405
gene id: 228405:HNE_RS03405
uniprot id: Q0C4D1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

228405:HNE RS16715
gene id: 228405:HNE_RS16715
uniprot id: Q0BWT9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

228405:HNE RS03660
gene id: 228405:HNE_RS03660
uniprot id: Q0C482
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

228405:HNE RS14095
gene id: 228405:HNE_RS14095
uniprot id: Q0BYB7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

228405:HNE RS14155
gene id: 228405:HNE_RS14155
uniprot id: Q0BYA5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

228405:HNE RS01755
gene id: 228405:HNE_RS01755
uniprot id: Q0C5B3
names: Cofactor
names: Function
names: Miscellaneous
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
messages: Membrane
messages: The Rieske protein is a high potential 2Fe-2S protein.
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

228405:HNE RS07305
gene id: 228405:HNE_RS07305
uniprot id: Q0C254
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

228405:HNE RS11275
gene id: 228405:HNE_RS11275
uniprot id: Q0BZW8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

228405:HNE RS15130
gene id: 228405:HNE_RS15130
uniprot id: Q0BXQ7
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

228405:HNE RS05110
gene id: 228405:HNE_RS05110
uniprot id: Q0C3E1
names: Similarity
messages: Belongs to the ClpA/ClpB family.

228405:HNE RS14395
gene id: 228405:HNE_RS14395
uniprot id: Q0BY54
names: Similarity
messages: Belongs to the peptidase M1 family.

228405:HNE RS14005
gene id: 228405:HNE_RS14005
uniprot id: Q0BYD5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Monomer.

228405:HNE RS17690
gene id: 228405:HNE_RS17690
uniprot id: Q0C5V2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

228405:HNE RS11700
gene id: 228405:HNE_RS11700
uniprot id: Q0BZN1
names: Function
messages: Acts on leucine, isoleucine and valine.

228405:HNE RS04765
gene id: 228405:HNE_RS04765
uniprot id: Q0C3K9
names: Similarity
messages: Belongs to the DODA-type extradiol aromatic ring-opening dioxygenase family.

228405:HNE RS14945
gene id: 228405:HNE_RS14945
uniprot id: Q0BXU5
names: Subcellular Location Annotation
messages: Membrane

228405:HNE RS15125
gene id: 228405:HNE_RS15125
uniprot id: Q0BXQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

228405:HNE RS14000
gene id: 228405:HNE_RS14000
uniprot id: Q0BYD6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

228405:HNE RS17820
gene id: 228405:HNE_RS17820
uniprot id: Q0C3E6
names: Similarity
messages: Belongs to the peptidase S11 family.

228405:HNE RS08880
gene id: 228405:HNE_RS08880
uniprot id: Q0C191
names: Similarity
messages: Belongs to the DNA photolyase family.

228405:HNE RS09590
gene id: 228405:HNE_RS09590
uniprot id: Q0C0V4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenine deaminase type 2 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism.

228405:HNE RS11690
gene id: 228405:HNE_RS11690
uniprot id: Q0BZN3
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

228405:HNE RS10205
gene id: 228405:HNE_RS10205
uniprot id: Q0C0I3
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

228405:HNE RS11520
gene id: 228405:HNE_RS11520
uniprot id: Q0BZR9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

228405:HNE RS03665
gene id: 228405:HNE_RS03665
uniprot id: Q0C481
names: Subcellular Location Annotation
messages: Membrane

228405:HNE RS17155
gene id: 228405:HNE_RS17155
uniprot id: Q0BWK2
names: Similarity
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

228405:HNE RS17250
gene id: 228405:HNE_RS17250
uniprot id: Q0BWI4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane

228405:HNE RS14140
gene id: 228405:HNE_RS14140
uniprot id: Q0BYA8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

228405:HNE RS00280
gene id: 228405:HNE_RS00280
uniprot id: Q0C653
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

228405:HNE RS06010
gene id: 228405:HNE_RS06010
uniprot id: Q0C2W3
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

228405:HNE RS13640
gene id: 228405:HNE_RS13640
uniprot id: Q0BYK7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

228405:HNE RS14285
gene id: 228405:HNE_RS14285
uniprot id: Q0BY77
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

228405:HNE RS17900
gene id: 228405:HNE_RS17900
uniprot id: Q0C280
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

228405:HNE RS15465
gene id: 228405:HNE_RS15465
uniprot id: Q0BXJ1
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

228405:HNE RS12860
gene id: 228405:HNE_RS12860
uniprot id: Q0BZ02
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

228405:HNE RS02735
gene id: 228405:HNE_RS02735
uniprot id: Q0C4R6
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

228405:HNE RS10310
gene id: 228405:HNE_RS10310
uniprot id: Q0C0G3
names: Similarity
names: Subunit
messages: Belongs to the P(II) protein family.
messages: Homotrimer.

228405:HNE RS03515
gene id: 228405:HNE_RS03515
uniprot id: Q0C4B1
names: Function
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family.
messages: Specifically catalyzes the dephosphorylation of 2-phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress.

228405:HNE RS00025
gene id: 228405:HNE_RS00025
uniprot id: Q0C6A4
names: Function
names: Subunit
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease.

228405:HNE RS08200
gene id: 228405:HNE_RS08200
uniprot id: Q0C1M5
names: Subcellular Location Annotation
messages: Membrane

228405:HNE RS13655
gene id: 228405:HNE_RS13655
uniprot id: Q0BYK4
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

228405:HNE RS05760
gene id: 228405:HNE_RS05760
uniprot id: Q0C314
names: Similarity
messages: Belongs to the UPF0174 family.

228405:HNE RS05740
gene id: 228405:HNE_RS05740
uniprot id: Q0C318
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

228405:HNE RS01340
gene id: 228405:HNE_RS01340
uniprot id: Q0C5J2
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

228405:HNE RS17135
gene id: 228405:HNE_RS17135
uniprot id: Q0BWK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

228405:HNE RS05845
gene id: 228405:HNE_RS05845
uniprot id: Q0C2Z7
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.

228405:HNE RS00020
gene id: 228405:HNE_RS00020
uniprot id: Q0C6A5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

228405:HNE RS00260
gene id: 228405:HNE_RS00260
uniprot id: Q0C657
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

228405:HNE RS15295
gene id: 228405:HNE_RS15295
uniprot id: Q0BXM6
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

228405:HNE RS07365
gene id: 228405:HNE_RS07365
uniprot id: Q0C242
names: Similarity
messages: Belongs to the FrmR/RcnR family.

228405:HNE RS17180
gene id: 228405:HNE_RS17180
uniprot id: Q0BWJ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

228405:HNE RS02555
gene id: 228405:HNE_RS02555
uniprot id: Q0C4V1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

228405:HNE RS13230
gene id: 228405:HNE_RS13230
uniprot id: Q0BYT7
names: Subcellular Location Annotation
messages: Membrane

228405:HNE RS09135
gene id: 228405:HNE_RS09135
uniprot id: Q0C144
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.

228405:HNE RS07010
gene id: 228405:HNE_RS07010
uniprot id: Q0C2B4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
messages: Single-chain monomer with multiple functions.

228405:HNE RS09055
gene id: 228405:HNE_RS09055
uniprot id: Q0C160
names: Similarity
messages: Belongs to the Gfa family.

228405:HNE RS07500
gene id: 228405:HNE_RS07500
uniprot id: Q0C216
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

228405:HNE RS09805
gene id: 228405:HNE_RS09805
uniprot id: Q0C0R2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

228405:HNE RS13560
gene id: 228405:HNE_RS13560
uniprot id: Q0BYM3
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

228405:HNE RS14085
gene id: 228405:HNE_RS14085
uniprot id: Q0BYB9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

228405:HNE RS13405
gene id: 228405:HNE_RS13405
uniprot id: Q0BYQ3
names: Function
names: Similarity
messages: Belongs to the TrhO family.
messages: Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.

228405:HNE RS17190
gene id: 228405:HNE_RS17190
uniprot id: Q0BWJ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

228405:HNE RS15520
gene id: 228405:HNE_RS15520
uniprot id: Q0BXI1
names: Subcellular Location Annotation
messages: Membrane

228405:HNE RS04595
gene id: 228405:HNE_RS04595
uniprot id: Q0C3P4
names: Similarity
messages: Belongs to the GARS family.

228405:HNE RS06560
gene id: 228405:HNE_RS06560
uniprot id: Q0C2K4
names: Similarity
messages: Belongs to the Gfa family.

228405:HNE RS09145
gene id: 228405:HNE_RS09145
uniprot id: Q0C142
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

228405:HNE RS04290
gene id: 228405:HNE_RS04290
uniprot id: Q0C3V4
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

228405:HNE RS16050
gene id: 228405:HNE_RS16050
uniprot id: Q0BX75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Cell inner membrane
messages: Membrane

228405:HNE RS10050
gene id: 228405:HNE_RS10050
uniprot id: Q0C0L4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Membrane

228405:HNE RS11410
gene id: 228405:HNE_RS11410
uniprot id: Q0BZT9
names: Similarity
messages: Belongs to the FBPase class 2 family.

228405:HNE RS08775
gene id: 228405:HNE_RS08775
uniprot id: Q0C1B2
names: Similarity
messages: Belongs to the Skp family.

228405:HNE RS07495
gene id: 228405:HNE_RS07495
uniprot id: Q0C217
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Cob(I)alamin adenosyltransferase family.
messages: Cytoplasm
messages: Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids.

228405:HNE RS17610
gene id: 228405:HNE_RS17610
uniprot id: Q0BWB0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.

228405:HNE RS04465
gene id: 228405:HNE_RS04465
uniprot id: Q0C3R9
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

228405:HNE RS11730
gene id: 228405:HNE_RS11730
uniprot id: Q0BZM4
names: Similarity
messages: Belongs to the LOG family.

228405:HNE RS04925
gene id: 228405:HNE_RS04925
uniprot id: Q0C3H7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Cell membrane
messages: Membrane

228405:HNE RS12655
gene id: 228405:HNE_RS12655
uniprot id: Q0BZ41
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

228405:HNE RS04720
gene id: 228405:HNE_RS04720
uniprot id: Q0C3L8
names: Subcellular Location Annotation
messages: Membrane

228405:HNE RS13790
gene id: 228405:HNE_RS13790
uniprot id: Q0BYH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

228405:HNE RS14025
gene id: 228405:HNE_RS14025
uniprot id: Q0BYD1
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

228405:HNE RS01775
gene id: 228405:HNE_RS01775
uniprot id: Q0C5A9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
messages: Catalyzes the reversible phosphorylation of S-methyl-5'-thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.
messages: Homohexamer. Dimer of a homotrimer.

228405:HNE RS03420
gene id: 228405:HNE_RS03420
uniprot id: Q0C4C8
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Catalyzes the reversible phosphorylation of pyruvate and phosphate.

228405:HNE RS05885
gene id: 228405:HNE_RS05885
uniprot id: Q0C2Y8
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

228405:HNE RS07310
gene id: 228405:HNE_RS07310
uniprot id: Q0C253
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

228405:HNE RS16180
gene id: 228405:HNE_RS16180
uniprot id: Q0BX50
names: Similarity
messages: Belongs to the Gfa family.

228405:HNE RS05375
gene id: 228405:HNE_RS05375
uniprot id: Q0C388
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

228405:HNE RS12565
gene id: 228405:HNE_RS12565
uniprot id: Q0BZ58
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

228405:HNE RS11200
gene id: 228405:HNE_RS11200
uniprot id: Q0BZY4
names: Caution
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

228405:HNE RS04040
gene id: 228405:HNE_RS04040
uniprot id: Q0C406
names: Similarity
names: Subunit
messages: Belongs to the beta-eliminating lyase family.
messages: Homotetramer.

228405:HNE RS12190
gene id: 228405:HNE_RS12190
uniprot id: Q0BZD1
names: Function
names: Similarity
messages: Belongs to the catalase family. HPII subfamily.
messages: Serves to protect cells from the toxic effects of hydrogen peroxide.

228405:HNE RS10675
gene id: 228405:HNE_RS10675
uniprot id: Q0C088
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

228405:HNE RS10925
gene id: 228405:HNE_RS10925
uniprot id: Q0C037
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

228405:HNE RS10135
gene id: 228405:HNE_RS10135
uniprot id: Q0C0J7
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

228405:HNE RS06720
gene id: 228405:HNE_RS06720
uniprot id: Q0C2H2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

228405:HNE RS03540
gene id: 228405:HNE_RS03540
uniprot id: Q0C4A6
names: Similarity
messages: Belongs to the class-II DAHP synthase family.

228405:HNE RS01760
gene id: 228405:HNE_RS01760
uniprot id: Q0C5B2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b family.
messages: Binds 2 heme groups non-covalently.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
messages: Membrane
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

228405:HNE RS06790
gene id: 228405:HNE_RS06790
uniprot id: Q0C2F8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family.
messages: Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.
messages: Cell inner membrane

228405:HNE RS07845
gene id: 228405:HNE_RS07845
uniprot id: Q0C1U6
names: Subcellular Location Annotation
messages: Membrane

228405:HNE RS14425
gene id: 228405:HNE_RS14425
uniprot id: Q0BY48
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

228405:HNE RS05525
gene id: 228405:HNE_RS05525
uniprot id: Q0C358
names: Function
names: Similarity
messages: Belongs to the polysaccharide deacetylase family.
messages: Is involved in generating a small heat-stable compound (Nod), an acylated oligomer of N-acetylglucosamine, that stimulates mitosis in various plant protoplasts.

228405:HNE RS06925
gene id: 228405:HNE_RS06925
uniprot id: Q0C2D1
names: Similarity
messages: Belongs to the biopterin-dependent aromatic amino acid hydroxylase family.

228405:HNE RS03360
gene id: 228405:HNE_RS03360
uniprot id: Q0C4E1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase E/G family. RNase E subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per homotetramer.
messages: Cell inner membrane
messages: Cytoplasm
messages: Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs.
messages: Homotetramer formed by a dimer of dimers.

228405:HNE RS16395
gene id: 228405:HNE_RS16395
uniprot id: Q0BX05
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

228405:HNE RS08820
gene id: 228405:HNE_RS08820
uniprot id: Q0C1A3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

228405:HNE RS13420
gene id: 228405:HNE_RS13420
uniprot id: Q0BYQ0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

228405:HNE RS10415
gene id: 228405:HNE_RS10415
uniprot id: Q0C0E1
names: Similarity
messages: Belongs to the MlaA family.

228405:HNE RS09835
gene id: 228405:HNE_RS09835
uniprot id: Q0C0Q6
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.

228405:HNE RS13465
gene id: 228405:HNE_RS13465
uniprot id: Q0BYP2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. N-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

228405:HNE RS09175
gene id: 228405:HNE_RS09175
uniprot id: Q0C136
names: Subcellular Location Annotation
messages: Membrane

228405:HNE RS10940
gene id: 228405:HNE_RS10940
uniprot id: Q0C034
names: Similarity
messages: Belongs to the TPP enzyme family.

228405:HNE RS11385
gene id: 228405:HNE_RS11385
uniprot id: Q0BZU4
names: Function
messages: Multidrug efflux pump.

228405:HNE RS10820
gene id: 228405:HNE_RS10820
uniprot id: Q0C058
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Member of a two-component regulatory system.

228405:HNE RS04405
gene id: 228405:HNE_RS04405
uniprot id: Q0C3T1
names: Subcellular Location Annotation
messages: Membrane

228405:HNE RS05625
gene id: 228405:HNE_RS05625
uniprot id: Q0C340
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

228405:HNE RS09375
gene id: 228405:HNE_RS09375
uniprot id: Q0C0Z7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase delta chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

228405:HNE RS14075
gene id: 228405:HNE_RS14075
uniprot id: Q0BYC1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

228405:HNE RS02915
gene id: 228405:HNE_RS02915
uniprot id: Q0C4M9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. NspC subfamily.
messages: Catalyzes the decarboxylation of carboxynorspermidine and carboxyspermidine.
messages: Cytoplasm
messages: Homodimer.

228405:HNE RS16450
gene id: 228405:HNE_RS16450
uniprot id: Q0BWZ4
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.

228405:HNE RS05160
gene id: 228405:HNE_RS05160
uniprot id: Q0C3D1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell inner membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
messages: Interacts with CtaA.

228405:HNE RS14045
gene id: 228405:HNE_RS14045
uniprot id: Q0BYC7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

228405:HNE RS16300
gene id: 228405:HNE_RS16300
uniprot id: Q0BX24
names: Subcellular Location Annotation
messages: Membrane

228405:HNE RS15040
gene id: 228405:HNE_RS15040
uniprot id: Q0BXS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane

228405:HNE RS14605
gene id: 228405:HNE_RS14605
uniprot id: Q0BY12
names: Similarity
messages: Belongs to the cytochrome P450 family.

228405:HNE RS05840
gene id: 228405:HNE_RS05840
uniprot id: Q0C2Z8
names: Cofactor
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

228405:HNE RS10955
gene id: 228405:HNE_RS10955
uniprot id: Q0C031
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

228405:HNE RS17380
gene id: 228405:HNE_RS17380
uniprot id: Q0BWF7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. CcmA exporter (TC 3.A.1.107) family.
messages: Cell inner membrane
messages: Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (CcmA) and two transmembrane proteins (CcmB).

228405:HNE RS15140
gene id: 228405:HNE_RS15140
uniprot id: Q0BXQ5
names: Similarity
messages: Belongs to the peptidase M13 family.

228405:HNE RS08905
gene id: 228405:HNE_RS08905
uniprot id: Q0C186
names: Similarity
messages: Belongs to the Gfa family.

228405:HNE RS14445
gene id: 228405:HNE_RS14445
uniprot id: Q0BY44
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MlaE permease family.
messages: Cell inner membrane
messages: Could be part of an ABC transporter complex.
messages: Membrane

228405:HNE RS11110
gene id: 228405:HNE_RS11110
uniprot id: Q0C002
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

228405:HNE RS06525
gene id: 228405:HNE_RS06525
uniprot id: Q0C2L1
names: Function
names: Similarity
messages: Belongs to the CcmH/CycL/Ccl2/NrfF family.
messages: Possible subunit of a heme lyase.

228405:HNE RS16920
gene id: 228405:HNE_RS16920
uniprot id: Q0BWP9
names: Similarity
messages: Belongs to the Gfa family.

228405:HNE RS13760
gene id: 228405:HNE_RS13760
uniprot id: Q0BYI3
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

228405:HNE RS14145
gene id: 228405:HNE_RS14145
uniprot id: Q0BYA7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

228405:HNE RS07985
gene id: 228405:HNE_RS07985
uniprot id: Q0C1R8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

228405:HNE RS14105
gene id: 228405:HNE_RS14105
uniprot id: Q0BYB5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

228405:HNE RS10060
gene id: 228405:HNE_RS10060
uniprot id: Q0C0L2
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

228405:HNE RS05565
gene id: 228405:HNE_RS05565
uniprot id: Q0C350
names: Function
messages: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.

228405:HNE RS10170
gene id: 228405:HNE_RS10170
uniprot id: Q0C0J0
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

228405:HNE RS03890
gene id: 228405:HNE_RS03890
uniprot id: Q0C435
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

228405:HNE RS07195
gene id: 228405:HNE_RS07195
uniprot id: Q0C275
names: Similarity
messages: Belongs to the YciI family.

228405:HNE RS02280
gene id: 228405:HNE_RS02280
uniprot id: Q0C507
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

228405:HNE RS16240
gene id: 228405:HNE_RS16240
uniprot id: Q0BX37
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MetA family.
messages: Cytoplasm
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

228405:HNE RS14060
gene id: 228405:HNE_RS14060
uniprot id: Q0BYC4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

228405:HNE RS16015
gene id: 228405:HNE_RS16015
uniprot id: Q0BX82
names: Similarity
messages: Belongs to the phosphohexose mutase family.

228405:HNE RS02910
gene id: 228405:HNE_RS02910
uniprot id: Q0C4N0
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

228405:HNE RS01965
gene id: 228405:HNE_RS01965
uniprot id: Q0C571
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsQ/DivIB family. FtsQ subfamily.
messages: Cell inner membrane
messages: Essential cell division protein.

228405:HNE RS06155
gene id: 228405:HNE_RS06155
uniprot id: Q0C2T4
names: Similarity
messages: Belongs to the LOG family.

228405:HNE RS05220
gene id: 228405:HNE_RS05220
uniprot id: Q0C3B8
names: Similarity
messages: Belongs to the band 7/mec-2 family.

228405:HNE RS06260
gene id: 228405:HNE_RS06260
uniprot id: Q0C2R4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

228405:HNE RS04865
gene id: 228405:HNE_RS04865
uniprot id: Q0C3I9
names: Similarity
messages: Belongs to the FAD-binding monooxygenase family.

228405:HNE RS03675
gene id: 228405:HNE_RS03675
uniprot id: Q0C479
names: Subcellular Location Annotation
messages: Membrane

228405:HNE RS01245
gene id: 228405:HNE_RS01245
uniprot id: Q0C5L1
names: Similarity
messages: Belongs to the MotB family.

228405:HNE RS13985
gene id: 228405:HNE_RS13985
uniprot id: Q0BYD9
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

228405:HNE RS02265
gene id: 228405:HNE_RS02265
uniprot id: Q0C510
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

228405:HNE RS13270
gene id: 228405:HNE_RS13270
uniprot id: Q0BYS9
names: Subcellular Location Annotation
messages: Membrane

228405:HNE RS14950
gene id: 228405:HNE_RS14950
uniprot id: Q0BXU4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

228405:HNE RS08755
gene id: 228405:HNE_RS08755
uniprot id: Q0C1B6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

228405:HNE RS14415
gene id: 228405:HNE_RS14415
uniprot id: Q0BY50
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

228405:HNE RS08555
gene id: 228405:HNE_RS08555
uniprot id: Q0C1F5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

228405:HNE RS15010
gene id: 228405:HNE_RS15010
uniprot id: Q0BXT2
names: Function
names: Similarity
messages: Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity.
messages: Belongs to the AhpD family.

228405:HNE RS00080
gene id: 228405:HNE_RS00080
uniprot id: Q0C693
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

228405:HNE RS01935
gene id: 228405:HNE_RS01935
uniprot id: Q0C577
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

228405:HNE RS04115
gene id: 228405:HNE_RS04115
uniprot id: Q0C3Z2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
messages: Homodimer.

228405:HNE RS17045
gene id: 228405:HNE_RS17045
uniprot id: Q0BWM3
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

228405:HNE RS03860
gene id: 228405:HNE_RS03860
uniprot id: Q0C441
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

228405:HNE RS02175
gene id: 228405:HNE_RS02175
uniprot id: Q0C528
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

228405:HNE RS09655
gene id: 228405:HNE_RS09655
uniprot id: Q0C0U1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
messages: Cytoplasm

228405:HNE RS01560
gene id: 228405:HNE_RS01560
uniprot id: Q0C5F4
names: Subcellular Location Annotation
messages: Membrane

228405:HNE RS07380
gene id: 228405:HNE_RS07380
uniprot id: Q0C238
names: Similarity
messages: Belongs to the pirin family.

228405:HNE RS07600
gene id: 228405:HNE_RS07600
uniprot id: Q0C1Z7
names: Subcellular Location Annotation
messages: Membrane

228405:HNE RS07580
gene id: 228405:HNE_RS07580
uniprot id: Q0C201
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

228405:HNE RS13700
gene id: 228405:HNE_RS13700
uniprot id: Q0BYJ5
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TtcA family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is chelated by three Cys residues, the fourth Fe has a free coordination site that may bind a sulfur atom transferred from the persulfide of IscS.
messages: Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.
messages: Cytoplasm
messages: Homodimer.
messages: The thiolation reaction likely consists of two steps: a first activation step by ATP to form an adenylated intermediate of the target base of tRNA, and a second nucleophilic substitution step of the sulfur (S) atom supplied by the hydrosulfide attached to the Fe-S cluster.

228405:HNE RS10680
gene id: 228405:HNE_RS10680
uniprot id: Q0C086
names: Similarity
messages: Belongs to the fabD family.

228405:HNE RS06045
gene id: 228405:HNE_RS06045
uniprot id: Q0C2V6
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

228405:HNE RS09410
gene id: 228405:HNE_RS09410
uniprot id: Q0C0Z0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

228405:HNE RS04175
gene id: 228405:HNE_RS04175
uniprot id: Q0C3Y0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

228405:HNE RS13815
gene id: 228405:HNE_RS13815
uniprot id: Q0BYH2
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 5 (UDGb) family.

228405:HNE RS04410
gene id: 228405:HNE_RS04410
uniprot id: Q0C3T0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

228405:HNE RS14500
gene id: 228405:HNE_RS14500
uniprot id: Q0BY33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

228405:HNE RS14290
gene id: 228405:HNE_RS14290
uniprot id: Q0BY76
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

228405:HNE RS00350
gene id: 228405:HNE_RS00350
uniprot id: Q0C639
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

228405:HNE RS07315
gene id: 228405:HNE_RS07315
uniprot id: Q0C252
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

228405:HNE RS17375
gene id: 228405:HNE_RS17375
uniprot id: Q0BWF8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.

228405:HNE RS09390
gene id: 228405:HNE_RS09390
uniprot id: Q0C0Z4
names: Similarity
messages: Belongs to the thioesterase PaaI family.

228405:HNE RS03970
gene id: 228405:HNE_RS03970
uniprot id: Q0C419
names: Similarity
messages: Belongs to the ABC transporter superfamily.

228405:HNE RS00110
gene id: 228405:HNE_RS00110
uniprot id: Q0C687
names: Similarity
messages: Belongs to the AHA1 family.

228405:HNE RS17675
gene id: 228405:HNE_RS17675
uniprot id: Q0C5Y7
names: Subcellular Location Annotation
messages: Cell membrane

228405:HNE RS10970
gene id: 228405:HNE_RS10970
uniprot id: Q0C028
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

228405:HNE RS05290
gene id: 228405:HNE_RS05290
uniprot id: Q0C3A5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaE family.
messages: Converts molybdopterin precursor Z into molybdopterin. This requires the incorporation of two sulfur atoms into precursor Z to generate a dithiolene group. The sulfur is provided by MoaD.
messages: Heterotetramer of 2 MoaD subunits and 2 MoaE subunits. Also stable as homodimer. The enzyme changes between these two forms during catalysis.

228405:HNE RS17175
gene id: 228405:HNE_RS17175
uniprot id: Q0BWJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

228405:HNE RS12550
gene id: 228405:HNE_RS12550
uniprot id: Q0BZ61
names: Similarity
messages: Belongs to the HsdR family.

228405:HNE RS13765
gene id: 228405:HNE_RS13765
uniprot id: Q0BYI2
names: Similarity
messages: Belongs to the Nudix hydrolase family.

228405:HNE RS02840
gene id: 228405:HNE_RS02840
uniprot id: Q0C4P5
names: Similarity
messages: Belongs to the cytochrome P450 family.

228405:HNE RS10195
gene id: 228405:HNE_RS10195
uniprot id: Q0C0I5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.

228405:HNE RS17660
gene id: 228405:HNE_RS17660
uniprot id: Q0C669
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

228405:HNE RS00010
gene id: 228405:HNE_RS00010
uniprot id: Q0C6A7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family.
messages: Cytoplasm
messages: Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

228405:HNE RS12355
gene id: 228405:HNE_RS12355
uniprot id: Q0BZ98
names: Similarity
messages: Belongs to the TPP enzyme family.

228405:HNE RS09170
gene id: 228405:HNE_RS09170
uniprot id: Q0C137
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
messages: Cytoplasm

228405:HNE RS01855
gene id: 228405:HNE_RS01855
uniprot id: Q0C593
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

228405:HNE RS14450
gene id: 228405:HNE_RS14450
uniprot id: Q0BY43
names: Cofactor
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.

228405:HNE RS15725
gene id: 228405:HNE_RS15725
uniprot id: Q0BXD9
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

228405:HNE RS04370
gene id: 228405:HNE_RS04370
uniprot id: Q0C3T8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell inner membrane
messages: Cytoplasm
messages: Monomer.

228405:HNE RS09645
gene id: 228405:HNE_RS09645
uniprot id: Q0C0U3
names: Similarity
messages: Belongs to the glutaredoxin family. Monothiol subfamily.

228405:HNE RS03645
gene id: 228405:HNE_RS03645
uniprot id: Q0C485
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

228405:HNE RS06825
gene id: 228405:HNE_RS06825
uniprot id: Q0C2F1
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

228405:HNE RS04935
gene id: 228405:HNE_RS04935
uniprot id: Q0C3H5
names: Subcellular Location Annotation
messages: Membrane

228405:HNE RS02075
gene id: 228405:HNE_RS02075
uniprot id: Q0C549
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell inner membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

228405:HNE RS15990
gene id: 228405:HNE_RS15990
uniprot id: Q0BX87
names: Similarity
messages: Belongs to the PhzF family.

228405:HNE RS00915
gene id: 228405:HNE_RS00915
uniprot id: Q0C5S5
names: Subcellular Location Annotation
messages: Membrane

228405:HNE RS12105
gene id: 228405:HNE_RS12105
uniprot id: Q0BZE9
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

228405:HNE RS09600
gene id: 228405:HNE_RS09600
uniprot id: Q0C0V2
names: Similarity
messages: Belongs to the DAMOX/DASOX family.

228405:HNE RS03805
gene id: 228405:HNE_RS03805
uniprot id: Q0C452
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

228405:HNE RS04985
gene id: 228405:HNE_RS04985
uniprot id: Q0C3G5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP12 family.
messages: Mitochondrion

228405:HNE RS08945
gene id: 228405:HNE_RS08945
uniprot id: Q0C178
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.

228405:HNE RS00390
gene id: 228405:HNE_RS00390
uniprot id: Q0C631
names: Similarity
messages: Belongs to the HpcH/HpaI aldolase family.

228405:HNE RS09755
gene id: 228405:HNE_RS09755
uniprot id: Q0C0S2
names: Subcellular Location Annotation
messages: Membrane

228405:HNE RS01490
gene id: 228405:HNE_RS01490
uniprot id: Q0C5G8
names: Subcellular Location Annotation
messages: Membrane

228405:HNE RS13705
gene id: 228405:HNE_RS13705
uniprot id: Q0BYJ4
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

228405:HNE RS06145
gene id: 228405:HNE_RS06145
uniprot id: Q0C2T6
names: Cofactor
messages: Can also use Mn(2+) ion.

228405:HNE RS12880
gene id: 228405:HNE_RS12880
uniprot id: Q0BYZ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

228405:HNE RS05065
gene id: 228405:HNE_RS05065
uniprot id: Q0C3E9
names: Similarity
messages: Belongs to the polysaccharide synthase family.

228405:HNE RS00410
gene id: 228405:HNE_RS00410
uniprot id: Q0C627
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm

228405:HNE RS08690
gene id: 228405:HNE_RS08690
uniprot id: Q0C1C9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

228405:HNE RS01520
gene id: 228405:HNE_RS01520
uniprot id: Q0C5G2
names: Similarity
messages: Belongs to the prokaryotic GSH synthase family.

228405:HNE RS12820
gene id: 228405:HNE_RS12820
uniprot id: Q0BZ10
names: Subcellular Location Annotation
messages: Membrane

228405:HNE RS03795
gene id: 228405:HNE_RS03795
uniprot id: Q0C454
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

228405:HNE RS07280
gene id: 228405:HNE_RS07280
uniprot id: Q0C259
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

228405:HNE RS09265
gene id: 228405:HNE_RS09265
uniprot id: Q0C119
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP L family.
messages: Cell inner membrane
messages: Membrane

228405:HNE RS08120
gene id: 228405:HNE_RS08120
uniprot id: Q0C1P0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Catalyzes the sodium-dependent uptake of extracellular L-proline.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

228405:HNE RS11330
gene id: 228405:HNE_RS11330
uniprot id: Q0BZV7
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

228405:HNE RS15755
gene id: 228405:HNE_RS15755
uniprot id: Q0BXD3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).

228405:HNE RS11550
gene id: 228405:HNE_RS11550
uniprot id: Q0BZR3
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

228405:HNE RS09935
gene id: 228405:HNE_RS09935
uniprot id: Q0C0N7
names: Subcellular Location Annotation
messages: Membrane

228405:HNE RS10380
gene id: 228405:HNE_RS10380
uniprot id: Q0C0E8
names: Similarity
messages: Belongs to the pyruvate kinase family.

228405:HNE RS03495
gene id: 228405:HNE_RS03495
uniprot id: Q0C4B3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Cell inner membrane
messages: Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.

228405:HNE RS17290
gene id: 228405:HNE_RS17290
uniprot id: Q0BWH6
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

228405:HNE RS00325
gene id: 228405:HNE_RS00325
uniprot id: Q0C644
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

228405:HNE RS08365
gene id: 228405:HNE_RS08365
uniprot id: Q0C1J3
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

228405:HNE RS08765
gene id: 228405:HNE_RS08765
uniprot id: Q0C1B4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

228405:HNE RS03340
gene id: 228405:HNE_RS03340
uniprot id: Q0C4E5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

228405:HNE RS12160
gene id: 228405:HNE_RS12160
uniprot id: Q0BZD8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Phosphonates importer (TC 3.A.1.9.1) family.
messages: Cell inner membrane
messages: Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (PhnC), two transmembrane proteins (PhnE) and a solute-binding protein (PhnD).

228405:HNE RS13010
gene id: 228405:HNE_RS13010
uniprot id: Q0BYX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

228405:HNE RS03810
gene id: 228405:HNE_RS03810
uniprot id: Q0C451
names: Similarity
messages: Belongs to the UPF0102 family.

228405:HNE RS14585
gene id: 228405:HNE_RS14585
uniprot id: Q0BY15
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

228405:HNE RS00505
gene id: 228405:HNE_RS00505
uniprot id: Q0C608
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell inner membrane
messages: Membrane

228405:HNE RS09970
gene id: 228405:HNE_RS09970
uniprot id: Q0C0N0
names: Function
names: Similarity
messages: Bifunctional enzyme that catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF).
messages: In the C-terminal section; belongs to the IspF family.
messages: In the N-terminal section; belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.

228405:HNE RS01990
gene id: 228405:HNE_RS01990
uniprot id: Q0C566
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

228405:HNE RS03245
gene id: 228405:HNE_RS03245
uniprot id: Q0C4G4
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

228405:HNE RS16265
gene id: 228405:HNE_RS16265
uniprot id: Q0BX32
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

228405:HNE RS03620
gene id: 228405:HNE_RS03620
uniprot id: Q0C490
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

228405:HNE RS03880
gene id: 228405:HNE_RS03880
uniprot id: Q0C437
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

228405:HNE RS03380
gene id: 228405:HNE_RS03380
uniprot id: Q0C4D7
names: Subcellular Location Annotation
messages: Membrane

228405:HNE RS09260
gene id: 228405:HNE_RS09260
uniprot id: Q0C120
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP K family.
messages: Cell inner membrane
messages: Membrane

228405:HNE RS06795
gene id: 228405:HNE_RS06795
uniprot id: Q0C2F7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

228405:HNE RS06310
gene id: 228405:HNE_RS06310
uniprot id: Q0C2Q3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

228405:HNE RS12725
gene id: 228405:HNE_RS12725
uniprot id: Q0BZ28
names: Function
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.

228405:HNE RS15710
gene id: 228405:HNE_RS15710
uniprot id: Q0BXE2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell inner membrane
messages: Cytoplasm
messages: May bind 1 zinc ion per subunit.
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

228405:HNE RS05725
gene id: 228405:HNE_RS05725
uniprot id: Q0C321
names: Similarity
messages: Belongs to the GSP E family.

228405:HNE RS14825
gene id: 228405:HNE_RS14825
uniprot id: Q0BXW9
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily.

228405:HNE RS06800
gene id: 228405:HNE_RS06800
uniprot id: Q0C2F6
names: Subcellular Location Annotation
messages: Membrane

228405:HNE RS15390
gene id: 228405:HNE_RS15390
uniprot id: Q0BXK7
names: Similarity
messages: Belongs to the GST superfamily.

228405:HNE RS08605
gene id: 228405:HNE_RS08605
uniprot id: Q0C1E6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity).

228405:HNE RS12815
gene id: 228405:HNE_RS12815
uniprot id: Q0BZ11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

228405:HNE RS00160
gene id: 228405:HNE_RS00160
uniprot id: Q0C677
names: Similarity
messages: Belongs to the N-acylglucosamine 2-epimerase family.

228405:HNE RS17225
gene id: 228405:HNE_RS17225
uniprot id: Q0BWI9
names: Similarity
messages: Belongs to the alkaline phosphatase family.

228405:HNE RS05495
gene id: 228405:HNE_RS05495
uniprot id: Q0C364
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

228405:HNE RS14130
gene id: 228405:HNE_RS14130
uniprot id: Q0BYB0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

228405:HNE RS15575
gene id: 228405:HNE_RS15575
uniprot id: Q0BXH1
names: Similarity
messages: Belongs to the peptidase S58 family.

228405:HNE RS01065
gene id: 228405:HNE_RS01065
uniprot id: Q0C5P5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

228405:HNE RS05540
gene id: 228405:HNE_RS05540
uniprot id: Q0C355
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

228405:HNE RS03095
gene id: 228405:HNE_RS03095
uniprot id: Q0C4J3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

228405:HNE RS16830
gene id: 228405:HNE_RS16830
uniprot id: Q0BWR6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

228405:HNE RS17265
gene id: 228405:HNE_RS17265
uniprot id: Q0BWI1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.

228405:HNE RS12970
gene id: 228405:HNE_RS12970
uniprot id: Q0BYX9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

228405:HNE RS06190
gene id: 228405:HNE_RS06190
uniprot id: Q0C2S8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
messages: Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.
messages: Cytoplasm
messages: Homodimer.

228405:HNE RS11230
gene id: 228405:HNE_RS11230
uniprot id: Q0BZX8
names: Similarity
messages: Belongs to the YjdM family.

228405:HNE RS07510
gene id: 228405:HNE_RS07510
uniprot id: Q0C214
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

228405:HNE RS17615
gene id: 228405:HNE_RS17615
uniprot id: Q0BWA9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

228405:HNE RS01445
gene id: 228405:HNE_RS01445
uniprot id: Q0C5H7
names: Similarity
messages: Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family.

228405:HNE RS00525
gene id: 228405:HNE_RS00525
uniprot id: Q0C603
names: Similarity
messages: Belongs to the UPF0053 family. Hemolysin C subfamily.

228405:HNE RS04920
gene id: 228405:HNE_RS04920
uniprot id: Q0C3H8
names: Similarity
messages: Belongs to the ArsC family.

228405:HNE RS00075
gene id: 228405:HNE_RS00075
uniprot id: Q0C694
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

228405:HNE RS01580
gene id: 228405:HNE_RS01580
uniprot id: Q0C5F0
names: Function
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

228405:HNE RS09770
gene id: 228405:HNE_RS09770
uniprot id: Q0C0R9
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

228405:HNE RS11950
gene id: 228405:HNE_RS11950
uniprot id: Q0BZI0
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

228405:HNE RS16140
gene id: 228405:HNE_RS16140
uniprot id: Q0BX58
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

228405:HNE RS07980
gene id: 228405:HNE_RS07980
uniprot id: Q0C1R9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

228405:HNE RS09360
gene id: 228405:HNE_RS09360
uniprot id: Q0C100
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

228405:HNE RS11370
gene id: 228405:HNE_RS11370
uniprot id: Q0BZU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

228405:HNE RS14270
gene id: 228405:HNE_RS14270
uniprot id: Q0BY80
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

228405:HNE RS05580
gene id: 228405:HNE_RS05580
uniprot id: Q0C348
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

228405:HNE RS02045
gene id: 228405:HNE_RS02045
uniprot id: Q0C555
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

228405:HNE RS17015
gene id: 228405:HNE_RS17015
uniprot id: Q0BWM9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

228405:HNE RS00545
gene id: 228405:HNE_RS00545
uniprot id: Q0C5Z9
names: Subcellular Location Annotation
messages: Cytoplasm

228405:HNE RS05950
gene id: 228405:HNE_RS05950
uniprot id: Q0C2X5
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

228405:HNE RS05440
gene id: 228405:HNE_RS05440
uniprot id: Q0C375
names: Similarity
messages: Belongs to the HpcH/HpaI aldolase family.

228405:HNE RS04215
gene id: 228405:HNE_RS04215
uniprot id: Q0C3X2
names: Function
names: Similarity
messages: Belongs to the ribF family.
messages: Catalyzes the phosphorylation of riboflavin to FMN followed by the adenylation of FMN to FAD.

228405:HNE RS08710
gene id: 228405:HNE_RS08710
uniprot id: Q0C1C5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 2 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
messages: Cytoplasm
messages: Homodimer.

228405:HNE RS09830
gene id: 228405:HNE_RS09830
uniprot id: Q0C0Q7
names: Similarity
messages: Belongs to the SdhE FAD assembly factor family.

228405:HNE RS12070
gene id: 228405:HNE_RS12070
uniprot id: Q0BZF6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

228405:HNE RS11810
gene id: 228405:HNE_RS11810
uniprot id: Q0BZK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

228405:HNE RS02575
gene id: 228405:HNE_RS02575
uniprot id: Q0C4U7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

228405:HNE RS01275
gene id: 228405:HNE_RS01275
uniprot id: Q0C5K5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FlgA family.
messages: Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly.
messages: Periplasm

228405:HNE RS07960
gene id: 228405:HNE_RS07960
uniprot id: Q0C1S4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

228405:HNE RS13330
gene id: 228405:HNE_RS13330
uniprot id: Q0BYR9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

228405:HNE RS17240
gene id: 228405:HNE_RS17240
uniprot id: Q0BWI6
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

228405:HNE RS15015
gene id: 228405:HNE_RS15015
uniprot id: Q0BXT1
names: Subcellular Location Annotation
messages: Cytoplasm

228405:HNE RS07660
gene id: 228405:HNE_RS07660
uniprot id: Q0C1Y2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaE family.
messages: Converts molybdopterin precursor Z into molybdopterin. This requires the incorporation of two sulfur atoms into precursor Z to generate a dithiolene group. The sulfur is provided by MoaD.
messages: Heterotetramer of 2 MoaD subunits and 2 MoaE subunits. Also stable as homodimer. The enzyme changes between these two forms during catalysis.

228405:HNE RS10790
gene id: 228405:HNE_RS10790
uniprot id: Q0C064
names: Similarity
messages: Belongs to the TPP enzyme family.

228405:HNE RS11255
gene id: 228405:HNE_RS11255
uniprot id: Q0BZX3
names: Subcellular Location Annotation
messages: Membrane

228405:HNE RS10350
gene id: 228405:HNE_RS10350
uniprot id: Q0C0F5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RlmJ family.
messages: Monomer.
messages: Specifically methylates the adenine in position 2030 of 23S rRNA.

228405:HNE RS03040
gene id: 228405:HNE_RS03040
uniprot id: Q0C4K4
names: Subcellular Location Annotation
messages: Membrane

228405:HNE RS09470
gene id: 228405:HNE_RS09470
uniprot id: Q0C0X8
names: Cofactor
names: Function
names: Similarity
messages: Adenine glycosylase active on G-A mispairs. MutY also corrects error-prone DNA synthesis past GO lesions which are due to the oxidatively damaged form of guanine: 7,8-dihydro-8-oxoguanine (8-oxo-dGTP).
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.

228405:HNE RS00450
gene id: 228405:HNE_RS00450
uniprot id: Q0C619
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.

228405:HNE RS00030
gene id: 228405:HNE_RS00030
uniprot id: Q0C6A3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecB family.
messages: Cytoplasm
messages: Homotetramer, a dimer of dimers. One homotetramer interacts with 1 SecA dimer.
messages: One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.

228405:HNE RS04965
gene id: 228405:HNE_RS04965
uniprot id: Q0C3G9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell inner membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.

228405:HNE RS11340
gene id: 228405:HNE_RS11340
uniprot id: Q0BZV5
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

228405:HNE RS00765
gene id: 228405:HNE_RS00765
uniprot id: Q0C5V5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TolB family.
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: Periplasm
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

228405:HNE RS00330
gene id: 228405:HNE_RS00330
uniprot id: Q0C643
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

228405:HNE RS01235
gene id: 228405:HNE_RS01235
uniprot id: Q0C5L3
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

228405:HNE RS05860
gene id: 228405:HNE_RS05860
uniprot id: Q0C2Z3
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

228405:HNE RS01940
gene id: 228405:HNE_RS01940
uniprot id: Q0C576
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamD family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

228405:HNE RS04360
gene id: 228405:HNE_RS04360
uniprot id: Q0C3U0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

228405:HNE RS13040
gene id: 228405:HNE_RS13040
uniprot id: Q0BYW6
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.

228405:HNE RS13015
gene id: 228405:HNE_RS13015
uniprot id: Q0BYX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

228405:HNE RS14100
gene id: 228405:HNE_RS14100
uniprot id: Q0BYB6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

228405:HNE RS08850
gene id: 228405:HNE_RS08850
uniprot id: Q0C197
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

228405:HNE RS07005
gene id: 228405:HNE_RS07005
uniprot id: Q0C2B5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.

228405:HNE RS05745
gene id: 228405:HNE_RS05745
uniprot id: Q0C317
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

228405:HNE RS09525
gene id: 228405:HNE_RS09525
uniprot id: Q0C0W7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

228405:HNE RS12580
gene id: 228405:HNE_RS12580
uniprot id: Q0BZ55
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

228405:HNE RS00465
gene id: 228405:HNE_RS00465
uniprot id: Q0C616
names: Similarity
messages: Belongs to the glutamate synthase family.

228405:HNE RS15000
gene id: 228405:HNE_RS15000
uniprot id: Q0BXT4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

228405:HNE RS03555
gene id: 228405:HNE_RS03555
uniprot id: Q0C4A3
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

228405:HNE RS13935
gene id: 228405:HNE_RS13935
uniprot id: Q0BYE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.
messages: Membrane

228405:HNE RS04740
gene id: 228405:HNE_RS04740
uniprot id: Q0C3L4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

228405:HNE RS14680
gene id: 228405:HNE_RS14680
uniprot id: Q0BXZ7
names: Similarity
messages: Belongs to the Dps family.

228405:HNE RS12075
gene id: 228405:HNE_RS12075
uniprot id: Q0BZF5
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

228405:HNE RS00960
gene id: 228405:HNE_RS00960
uniprot id: Q0C5R6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

228405:HNE RS05570
gene id: 228405:HNE_RS05570
uniprot id: Q0C349
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

228405:HNE RS03925
gene id: 228405:HNE_RS03925
uniprot id: Q0C428
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

228405:HNE RS10215
gene id: 228405:HNE_RS10215
uniprot id: Q0C0I1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.

228405:HNE RS08595
gene id: 228405:HNE_RS08595
uniprot id: Q0C1E8
names: Similarity
messages: Belongs to the bacterial glucokinase family.

228405:HNE RS13385
gene id: 228405:HNE_RS13385
uniprot id: Q0BYQ7
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

228405:HNE RS03655
gene id: 228405:HNE_RS03655
uniprot id: Q0C483
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

228405:HNE RS02865
gene id: 228405:HNE_RS02865
uniprot id: Q0C4P0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

228405:HNE RS09405
gene id: 228405:HNE_RS09405
uniprot id: Q0C0Z1
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

228405:HNE RS13755
gene id: 228405:HNE_RS13755
uniprot id: Q0BYI4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

228405:HNE RS10695
gene id: 228405:HNE_RS10695
uniprot id: Q0C083
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

228405:HNE RS09520
gene id: 228405:HNE_RS09520
uniprot id: Q0C0W8
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

228405:HNE RS05910
gene id: 228405:HNE_RS05910
uniprot id: Q0C2Y3
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

228405:HNE RS06930
gene id: 228405:HNE_RS06930
uniprot id: Q0C2D0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

228405:HNE RS08190
gene id: 228405:HNE_RS08190
uniprot id: Q0C1M7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

228405:HNE RS01865
gene id: 228405:HNE_RS01865
uniprot id: Q0C591
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

228405:HNE RS08795
gene id: 228405:HNE_RS08795
uniprot id: Q0C1A8
names: Function
names: Similarity
messages: Belongs to the LpxB family.
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

228405:HNE RS13855
gene id: 228405:HNE_RS13855
uniprot id: Q0BYG4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

228405:HNE RS14175
gene id: 228405:HNE_RS14175
uniprot id: Q0BYA0
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

228405:HNE RS06110
gene id: 228405:HNE_RS06110
uniprot id: Q0C2U3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Binds 1 copper ion per subunit, denoted as copper B.
messages: Binds 2 heme groups per subunit, denoted as high- and low-spin.
messages: Membrane

228405:HNE RS00770
gene id: 228405:HNE_RS00770
uniprot id: Q0C5V4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Pal lipoprotein family.
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

228405:HNE RS16955
gene id: 228405:HNE_RS16955
uniprot id: Q0BWP1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

228405:HNE RS01615
gene id: 228405:HNE_RS01615
uniprot id: Q0C5E2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

228405:HNE RS11085
gene id: 228405:HNE_RS11085
uniprot id: Q0C007
names: Subcellular Location Annotation
messages: Membrane

228405:HNE RS03055
gene id: 228405:HNE_RS03055
uniprot id: Q0C4K1
names: Similarity
messages: Belongs to the group II decarboxylase family.

228405:HNE RS14265
gene id: 228405:HNE_RS14265
uniprot id: Q0BY81
names: Subcellular Location Annotation
messages: Membrane

228405:HNE RS15370
gene id: 228405:HNE_RS15370
uniprot id: Q0BXL1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

228405:HNE RS08445
gene id: 228405:HNE_RS08445
uniprot id: Q0C1H8
names: Similarity
messages: Belongs to the FrmR/RcnR family.

228405:HNE RS02165
gene id: 228405:HNE_RS02165
uniprot id: Q0C530
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

228405:HNE RS04875
gene id: 228405:HNE_RS04875
uniprot id: Q0C3I7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

228405:HNE RS08495
gene id: 228405:HNE_RS08495
uniprot id: Q0C1G6
names: Similarity
messages: Belongs to the TrbG/VirB9 family.

228405:HNE RS14150
gene id: 228405:HNE_RS14150
uniprot id: Q0BYA6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

228405:HNE RS04725
gene id: 228405:HNE_RS04725
uniprot id: Q0C3L7
names: Subcellular Location Annotation
messages: Membrane

228405:HNE RS01575
gene id: 228405:HNE_RS01575
uniprot id: Q0C5F1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-ketoglutarate dehydrogenase family.
messages: E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).
messages: Homodimer. Part of the 2-oxoglutarate dehydrogenase (OGDH) complex composed of E1 (2-oxoglutarate dehydrogenase), E2 (dihydrolipoamide succinyltransferase) and E3 (dihydrolipoamide dehydrogenase); the complex contains multiple copies of the three enzymatic components (E1, E2 and E3).

228405:HNE RS10175
gene id: 228405:HNE_RS10175
uniprot id: Q0C0I9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

228405:HNE RS09355
gene id: 228405:HNE_RS09355
uniprot id: Q0C101
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

228405:HNE RS07880
gene id: 228405:HNE_RS07880
uniprot id: Q0C1T9
names: Subcellular Location Annotation
messages: Membrane

228405:HNE RS14755
gene id: 228405:HNE_RS14755
uniprot id: Q0BXY3
names: Similarity
messages: Belongs to the FAD-binding monooxygenase family.

228405:HNE RS15225
gene id: 228405:HNE_RS15225
uniprot id: Q0BXN8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

228405:HNE RS16400
gene id: 228405:HNE_RS16400
uniprot id: Q0BX04
names: Similarity
messages: Belongs to the formate--tetrahydrofolate ligase family.

228405:HNE RS01920
gene id: 228405:HNE_RS01920
uniprot id: Q0C580
names: Function
messages: Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins.

228405:HNE RS15455
gene id: 228405:HNE_RS15455
uniprot id: Q0BXJ3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

228405:HNE RS13725
gene id: 228405:HNE_RS13725
uniprot id: Q0BYJ0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

228405:HNE RS01495
gene id: 228405:HNE_RS01495
uniprot id: Q0C5G7
names: Similarity
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the malic enzymes family.

228405:HNE RS00945
gene id: 228405:HNE_RS00945
uniprot id: Q0C5R9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell inner membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.

228405:HNE RS15795
gene id: 228405:HNE_RS15795
uniprot id: Q0BXC5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

228405:HNE RS13830
gene id: 228405:HNE_RS13830
uniprot id: Q0BYG9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

228405:HNE RS16030
gene id: 228405:HNE_RS16030
uniprot id: Q0BX79
names: Subcellular Location Annotation
messages: Membrane

228405:HNE RS12910
gene id: 228405:HNE_RS12910
uniprot id: Q0BYZ2
names: Similarity
messages: Belongs to the HesB/IscA family.

228405:HNE RS13380
gene id: 228405:HNE_RS13380
uniprot id: Q0BYQ8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Cytoplasm
messages: Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

228405:HNE RS04355
gene id: 228405:HNE_RS04355
uniprot id: Q0C3U1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.

228405:HNE RS16610
gene id: 228405:HNE_RS16610
uniprot id: Q0BWW0
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.

228405:HNE RS13650
gene id: 228405:HNE_RS13650
uniprot id: Q0BYK5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

228405:HNE RS08730
gene id: 228405:HNE_RS08730
uniprot id: Q0C1C1
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

228405:HNE RS00950
gene id: 228405:HNE_RS00950
uniprot id: Q0C5R8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

228405:HNE RS07710
gene id: 228405:HNE_RS07710
uniprot id: Q0C1X2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
messages: Cell membrane
messages: Membrane

228405:HNE RS04110
gene id: 228405:HNE_RS04110
uniprot id: Q0C3Z3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

228405:HNE RS11755
gene id: 228405:HNE_RS11755
uniprot id: Q0BZM0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

228405:HNE RS14090
gene id: 228405:HNE_RS14090
uniprot id: Q0BYB8
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

228405:HNE RS05280
gene id: 228405:HNE_RS05280
uniprot id: Q0C3A7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

228405:HNE RS16990
gene id: 228405:HNE_RS16990
uniprot id: Q0BWN4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

228405:HNE RS01090
gene id: 228405:HNE_RS01090
uniprot id: Q0C5P0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

228405:HNE RS16670
gene id: 228405:HNE_RS16670
uniprot id: Q0BWU8
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

228405:HNE RS07535
gene id: 228405:HNE_RS07535
uniprot id: Q0C210
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

228405:HNE RS14845
gene id: 228405:HNE_RS14845
uniprot id: Q0BXW5
names: Caution
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

228405:HNE RS04425
gene id: 228405:HNE_RS04425
uniprot id: Q0C3S7
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

228405:HNE RS05380
gene id: 228405:HNE_RS05380
uniprot id: Q0C387
names: Subcellular Location Annotation
messages: Membrane

228405:HNE RS14310
gene id: 228405:HNE_RS14310
uniprot id: Q0BY72
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

228405:HNE RS02110
gene id: 228405:HNE_RS02110
uniprot id: Q0C542
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family.
messages: Cytoplasm
messages: Homotrimer.

228405:HNE RS05265
gene id: 228405:HNE_RS05265
uniprot id: Q0C3A9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

228405:HNE RS02590
gene id: 228405:HNE_RS02590
uniprot id: Q0C4U4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell inner membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Membrane

228405:HNE RS09575
gene id: 228405:HNE_RS09575
uniprot id: Q0C0V7
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

228405:HNE RS12440
gene id: 228405:HNE_RS12440
uniprot id: Q0BZ81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

228405:HNE RS14480
gene id: 228405:HNE_RS14480
uniprot id: Q0BY37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0382 family.
messages: Membrane

228405:HNE RS03550
gene id: 228405:HNE_RS03550
uniprot id: Q0C4A4
names: Function
messages: Multidrug efflux pump.

228405:HNE RS16960
gene id: 228405:HNE_RS16960
uniprot id: Q0BWP0
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

228405:HNE RS00225
gene id: 228405:HNE_RS00225
uniprot id: Q0C664
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

228405:HNE RS15485
gene id: 228405:HNE_RS15485
uniprot id: Q0BXI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM86 family.
messages: Membrane

228405:HNE RS05275
gene id: 228405:HNE_RS05275
uniprot id: Q0C3A8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

228405:HNE RS01670
gene id: 228405:HNE_RS01670
uniprot id: Q0C5D1
names: Subcellular Location Annotation
messages: Membrane

228405:HNE RS13860
gene id: 228405:HNE_RS13860
uniprot id: Q0BYG3
names: Similarity
messages: Belongs to the transglycosylase Slt family.
messages: Belongs to the virb1 family.

228405:HNE RS17120
gene id: 228405:HNE_RS17120
uniprot id: Q0BWK8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

228405:HNE RS01910
gene id: 228405:HNE_RS01910
uniprot id: Q0C582
names: Similarity
messages: Belongs to the peptidase M24B family.

228405:HNE RS17465
gene id: 228405:HNE_RS17465
uniprot id: Q0BWD9
names: Similarity
messages: Belongs to the ArsC family.

228405:HNE RS05325
gene id: 228405:HNE_RS05325
uniprot id: Q0C398
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

228405:HNE RS14645
gene id: 228405:HNE_RS14645
uniprot id: Q0BY04
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

228405:HNE RS02345
gene id: 228405:HNE_RS02345
uniprot id: Q0C4Z3
names: Function
names: Similarity
messages: Belongs to the band 7/mec-2 family. HflC subfamily.
messages: HflC and HflK could regulate a protease.

228405:HNE RS01955
gene id: 228405:HNE_RS01955
uniprot id: Q0C573
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

228405:HNE RS08930
gene id: 228405:HNE_RS08930
uniprot id: Q0C181
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

228405:HNE RS04375
gene id: 228405:HNE_RS04375
uniprot id: Q0C3T7
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

228405:HNE RS03935
gene id: 228405:HNE_RS03935
uniprot id: Q0C426
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

228405:HNE RS03920
gene id: 228405:HNE_RS03920
uniprot id: Q0C429
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

228405:HNE RS09925
gene id: 228405:HNE_RS09925
uniprot id: Q0C0N9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

228405:HNE RS05140
gene id: 228405:HNE_RS05140
uniprot id: Q0C3D5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

228405:HNE RS11460
gene id: 228405:HNE_RS11460
uniprot id: Q0BZT0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the COX15/CtaA family. Type 2 subfamily.
messages: Catalyzes the conversion of heme O to heme A by two successive hydroxylations of the methyl group at C8. The first hydroxylation forms heme I, the second hydroxylation results in an unstable dihydroxymethyl group, which spontaneously dehydrates, resulting in the formyl group of heme A.
messages: Cell membrane
messages: Interacts with CtaB.

228405:HNE RS13220
gene id: 228405:HNE_RS13220
uniprot id: Q0BYT9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the trans-sulfuration enzymes family. MetZ subfamily.
messages: Catalyzes the formation of L-homocysteine from O-succinyl-L-homoserine (OSHS) and hydrogen sulfide.
messages: Homotetramer.

228405:HNE RS08135
gene id: 228405:HNE_RS08135
uniprot id: Q0C1N7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

228405:HNE RS04815
gene id: 228405:HNE_RS04815
uniprot id: Q0C3K0
names: Similarity
messages: Belongs to the pirin family.

228405:HNE RS06695
gene id: 228405:HNE_RS06695
uniprot id: Q0C2H7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

228405:HNE RS07745
gene id: 228405:HNE_RS07745
uniprot id: Q0C1W5
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.

228405:HNE RS06195
gene id: 228405:HNE_RS06195
uniprot id: Q0C2S7
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

228405:HNE RS07485
gene id: 228405:HNE_RS07485
uniprot id: Q0C219
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell inner membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Membrane

228405:HNE RS03430
gene id: 228405:HNE_RS03430
uniprot id: Q0C4C6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

228405:HNE RS14700
gene id: 228405:HNE_RS14700
uniprot id: Q0BXZ3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

228405:HNE RS03375
gene id: 228405:HNE_RS03375
uniprot id: Q0C4D8
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

228405:HNE RS01870
gene id: 228405:HNE_RS01870
uniprot id: Q0C590
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

228405:HNE RS12560
gene id: 228405:HNE_RS12560
uniprot id: Q0BZ59
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

228405:HNE RS17185
gene id: 228405:HNE_RS17185
uniprot id: Q0BWJ6
names: Similarity
messages: Belongs to the CutA family.

228405:HNE RS05355
gene id: 228405:HNE_RS05355
uniprot id: Q0C392
names: Similarity
messages: Belongs to the HMG-CoA lyase family.

228405:HNE RS16850
gene id: 228405:HNE_RS16850
uniprot id: Q0BWR2
names: Similarity
names: Subunit
messages: Belongs to the P(II) protein family.
messages: Homotrimer.

228405:HNE RS10530
gene id: 228405:HNE_RS10530
uniprot id: Q0C0B7
names: Similarity
messages: Belongs to the sodium:galactoside symporter (TC 2.A.2) family.

228405:HNE RS00860
gene id: 228405:HNE_RS00860
uniprot id: Q0C5T6
names: Similarity
messages: Belongs to the OmpW/AlkL family.

228405:HNE RS11285
gene id: 228405:HNE_RS11285
uniprot id: Q0BZW6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

228405:HNE RS17685
gene id: 228405:HNE_RS17685
uniprot id: Q0C5V3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CpoB family.
messages: Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division.
messages: Periplasm

228405:HNE RS11450
gene id: 228405:HNE_RS11450
uniprot id: Q0BZT2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

228405:HNE RS09310
gene id: 228405:HNE_RS09310
uniprot id: Q0C110
names: Similarity
messages: Belongs to the thioredoxin family.

228405:HNE RS18215
gene id: 228405:HNE_RS18215
uniprot id: Q0BWS5
names: Subcellular Location Annotation
messages: Membrane

228405:HNE RS09030
gene id: 228405:HNE_RS09030
uniprot id: Q0C164
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

228405:HNE RS17485
gene id: 228405:HNE_RS17485
uniprot id: Q0BWD5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EamA transporter family.
messages: Membrane

228405:HNE RS16545
gene id: 228405:HNE_RS16545
uniprot id: Q0BWX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Membrane

228405:HNE RS10700
gene id: 228405:HNE_RS10700
uniprot id: Q0C082
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins.

228405:HNE RS07785
gene id: 228405:HNE_RS07785
uniprot id: Q0C1V8
names: Similarity
messages: Belongs to the glycosyltransferase 20 family.

228405:HNE RS16705
gene id: 228405:HNE_RS16705
uniprot id: Q0BWU1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

228405:HNE RS04775
gene id: 228405:HNE_RS04775
uniprot id: Q0C3K7
names: Subcellular Location Annotation
messages: Cytoplasm

228405:HNE RS15770
gene id: 228405:HNE_RS15770
uniprot id: Q0BXD0
names: Similarity
messages: Belongs to the FAD-binding monooxygenase family.

228405:HNE RS14335
gene id: 228405:HNE_RS14335
uniprot id: Q0BY66
names: Similarity
messages: Belongs to the extradiol ring-cleavage dioxygenase family.

228405:HNE RS08645
gene id: 228405:HNE_RS08645
uniprot id: Q0C1D8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the complex I 75 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

228405:HNE RS16680
gene id: 228405:HNE_RS16680
uniprot id: Q0BWU6
names: Similarity
messages: Belongs to the HMG-CoA lyase family.

228405:HNE RS11170
gene id: 228405:HNE_RS11170
uniprot id: Q0BZZ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase D family.
messages: Cytoplasm
messages: Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides.

228405:HNE RS04680
gene id: 228405:HNE_RS04680
uniprot id: Q0C3M6
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

228405:HNE RS02705
gene id: 228405:HNE_RS02705
uniprot id: Q0C4S1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

228405:HNE RS04385
gene id: 228405:HNE_RS04385
uniprot id: Q0C3T5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.
messages: Cell membrane
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

228405:HNE RS11440
gene id: 228405:HNE_RS11440
uniprot id: Q0BZT4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 2 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

228405:HNE RS13065
gene id: 228405:HNE_RS13065
uniprot id: Q0BYW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1C family.
messages: Periplasm

228405:HNE RS05710
gene id: 228405:HNE_RS05710
uniprot id: Q0C324
names: Similarity
messages: Belongs to the bacterial secretin family.

228405:HNE RS09540
gene id: 228405:HNE_RS09540
uniprot id: Q0C0W4
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

228405:HNE RS08370
gene id: 228405:HNE_RS08370
uniprot id: Q0C1J2
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

228405:HNE RS07705
gene id: 228405:HNE_RS07705
uniprot id: Q0C1X3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
messages: Membrane

228405:HNE RS14980
gene id: 228405:HNE_RS14980
uniprot id: Q0BXT8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

228405:HNE RS04945
gene id: 228405:HNE_RS04945
uniprot id: Q0C3H2
names: Similarity
messages: Belongs to the universal stress protein A family.

228405:HNE RS17585
gene id: 228405:HNE_RS17585
uniprot id: Q0BWB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

228405:HNE RS14975
gene id: 228405:HNE_RS14975
uniprot id: Q0BXT9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell inner membrane

228405:HNE RS00580
gene id: 228405:HNE_RS00580
uniprot id: Q0C5Z2
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

228405:HNE RS14815
gene id: 228405:HNE_RS14815
uniprot id: Q0BXX1
names: Function
names: Subunit
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
messages: Homodimer. Part of the PDH complex, consisting of multiple copies of pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

228405:HNE RS09780
gene id: 228405:HNE_RS09780
uniprot id: Q0C0R7
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.

228405:HNE RS08650
gene id: 228405:HNE_RS08650
uniprot id: Q0C1D7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

228405:HNE RS17620
gene id: 228405:HNE_RS17620
uniprot id: Q0BWA8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.

228405:HNE RS06520
gene id: 228405:HNE_RS06520
uniprot id: Q0C2L2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1C family.
messages: Periplasm

228405:HNE RS11130
gene id: 228405:HNE_RS11130
uniprot id: Q0BZZ8
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

228405:HNE RS17170
gene id: 228405:HNE_RS17170
uniprot id: Q0BWJ9
names: Function
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.
messages: Functions in two distinct reactions of the de novo folate biosynthetic pathway. Catalyzes the addition of a glutamate residue to dihydropteroate (7,8-dihydropteroate or H2Pte) to form dihydrofolate (7,8-dihydrofolate monoglutamate or H2Pte-Glu). Also catalyzes successive additions of L-glutamate to tetrahydrofolate or 10-formyltetrahydrofolate or 5,10-methylenetetrahydrofolate, leading to folylpolyglutamate derivatives.

228405:HNE RS10165
gene id: 228405:HNE_RS10165
uniprot id: Q0C0J1
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

228405:HNE RS06975
gene id: 228405:HNE_RS06975
uniprot id: Q0C2C1
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

228405:HNE RS13070
gene id: 228405:HNE_RS13070
uniprot id: Q0BYW0
names: Similarity
messages: Belongs to the sodium:galactoside symporter (TC 2.A.2) family.