227882:SAVERM RS19035
gene id: 227882:SAVERM_RS19035
uniprot id: Q82H57
names: Function
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.
messages: Catalyzes the ATP-dependent phosphorylation of fructose-l-phosphate to fructose-l,6-bisphosphate.

227882:SAVERM RS13910
gene id: 227882:SAVERM_RS13910
uniprot id: Q82JT2
names: Similarity
messages: Belongs to the heat shock protein 90 family.

227882:SAVERM RS21005
gene id: 227882:SAVERM_RS21005
uniprot id: Q82G21
names: Similarity
messages: Belongs to the PhoU family.
messages: Belongs to the UPF0111 family.

227882:SAVERM RS24380
gene id: 227882:SAVERM_RS24380
uniprot id: Q82E92
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

227882:SAVERM RS18955
gene id: 227882:SAVERM_RS18955
uniprot id: Q82H75
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

227882:SAVERM RS33310
gene id: 227882:SAVERM_RS33310
uniprot id: Q829D0
names: Subcellular Location Annotation
messages: Membrane

227882:SAVERM RS18620
gene id: 227882:SAVERM_RS18620
uniprot id: Q82HA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SsgA family.
messages: Cell septum

227882:SAVERM RS30900
gene id: 227882:SAVERM_RS30900
uniprot id: Q82AQ9
names: Similarity
messages: Belongs to the glutamine synthetase family.

227882:SAVERM RS07720
gene id: 227882:SAVERM_RS07720
uniprot id: Q82N52
names: Similarity
messages: Belongs to the glycosyl hydrolase 42 family.

227882:SAVERM RS25585
gene id: 227882:SAVERM_RS25585
uniprot id: Q82DL8
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

227882:SAVERM RS04910
gene id: 227882:SAVERM_RS04910
uniprot id: Q82PL5
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

227882:SAVERM RS34320
gene id: 227882:SAVERM_RS34320
uniprot id: Q828J0
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic ubiquitin-like protein family.
messages: Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation.
messages: Strongly interacts with the proteasome-associated ATPase ARC through a hydrophobic interface; the interacting region of Pup lies in its C-terminal half. There is one Pup binding site per ARC hexamer ring.
messages: The N-terminal unstructured half of Pup provides a signal required to initiate unfolding and degradation by the proteasome but is not needed for pupylation, while the C-terminal helical half of Pup interacts with ARC to target proteins to the proteasome.

227882:SAVERM RS25330
gene id: 227882:SAVERM_RS25330
uniprot id: Q82DR2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Catalyzes the reversible conversion of aspartate and 2-oxoglutarate to glutamate and oxaloacetate (PubMed:24302739). Does not have prephenate aminotransferase activity (PubMed:24302739).
messages: Cytoplasm
messages: Homodimer.

227882:SAVERM RS06305
gene id: 227882:SAVERM_RS06305
uniprot id: Q82NX8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

227882:SAVERM RS25440
gene id: 227882:SAVERM_RS25440
uniprot id: Q82DP2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

227882:SAVERM RS11675
gene id: 227882:SAVERM_RS11675
uniprot id: Q82KY5
names: Subcellular Location Annotation
messages: Membrane

227882:SAVERM RS31540
gene id: 227882:SAVERM_RS31540
uniprot id: Q82AD5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

227882:SAVERM RS08205
gene id: 227882:SAVERM_RS08205
uniprot id: Q82MV6
names: Similarity
messages: Belongs to the LacAB/RpiB family.

227882:SAVERM RS31150
gene id: 227882:SAVERM_RS31150
uniprot id: Q82AL1
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
messages: Belongs to the sulfur carrier protein TusA family.

227882:SAVERM RS18985
gene id: 227882:SAVERM_RS18985
uniprot id: Q82H69
names: Subcellular Location Annotation
messages: Membrane

227882:SAVERM RS35300
gene id: 227882:SAVERM_RS35300
uniprot id: Q827Q6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

227882:SAVERM RS26235
gene id: 227882:SAVERM_RS26235
uniprot id: Q82D96
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.

227882:SAVERM RS19955
gene id: 227882:SAVERM_RS19955
uniprot id: Q82GN4
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

227882:SAVERM RS41235
gene id: 227882:SAVERM_RS41235
uniprot id: Q82PN3
names: Similarity
messages: Belongs to the cytochrome P450 family.

227882:SAVERM RS10880
gene id: 227882:SAVERM_RS10880
uniprot id: Q82LE0
names: Similarity
messages: Belongs to the CdaR family.

227882:SAVERM RS27120
gene id: 227882:SAVERM_RS27120
uniprot id: Q82CT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

227882:SAVERM RS34750
gene id: 227882:SAVERM_RS34750
uniprot id: Q828A2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

227882:SAVERM RS02405
gene id: 227882:SAVERM_RS02405
uniprot id: Q82QW4
names: Similarity
messages: Belongs to the myoviridae tail sheath protein family.

227882:SAVERM RS16220
gene id: 227882:SAVERM_RS16220
uniprot id: Q82IK4
names: Cofactor
names: Function
messages: Binds 1 [3Fe-4S] cluster.
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

227882:SAVERM RS14655
gene id: 227882:SAVERM_RS14655
uniprot id: Q82JD8
names: Subcellular Location Annotation
messages: Cytoplasm

227882:SAVERM RS16695
gene id: 227882:SAVERM_RS16695
uniprot id: Q82ID4
names: Similarity
messages: Belongs to the catalase family.

227882:SAVERM RS02520
gene id: 227882:SAVERM_RS02520
uniprot id: Q82QU1
names: Function
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

227882:SAVERM RS28695
gene id: 227882:SAVERM_RS28695
uniprot id: Q82BZ4
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

227882:SAVERM RS36510
gene id: 227882:SAVERM_RS36510
uniprot id: Q826R8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UreF family.
messages: Cytoplasm
messages: Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
messages: UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

227882:SAVERM RS01930
gene id: 227882:SAVERM_RS01930
uniprot id: Q82R51
names: Subcellular Location Annotation
messages: Membrane

227882:SAVERM RS25660
gene id: 227882:SAVERM_RS25660
uniprot id: Q82DK2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

227882:SAVERM RS25420
gene id: 227882:SAVERM_RS25420
uniprot id: P66338
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

227882:SAVERM RS05065
gene id: 227882:SAVERM_RS05065
uniprot id: Q82PI5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpC family.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

227882:SAVERM RS30915
gene id: 227882:SAVERM_RS30915
uniprot id: Q82AQ7
names: Similarity
messages: Belongs to the ArsC family.

227882:SAVERM RS32480
gene id: 227882:SAVERM_RS32480
uniprot id: Q829U5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 2 subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

227882:SAVERM RS32940
gene id: 227882:SAVERM_RS32940
uniprot id: Q829K5
names: Similarity
messages: Belongs to the CobH/CbiC family.

227882:SAVERM RS35650
gene id: 227882:SAVERM_RS35650
uniprot id: Q827I4
names: Similarity
messages: Belongs to the D-glutamate cyclase family.

227882:SAVERM RS15450
gene id: 227882:SAVERM_RS15450
uniprot id: Q82J11
names: Subcellular Location Annotation
messages: Cell membrane

227882:SAVERM RS31190
gene id: 227882:SAVERM_RS31190
uniprot id: Q82AK3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Rieske iron-sulfur protein family.
messages: Cell membrane
messages: Iron-sulfur subunit of the cytochrome bc1 complex, an essential component of the respiratory electron transport chain required for ATP synthesis. The bc1 complex catalyzes the oxidation of menaquinol and the reduction of cytochrome c in the respiratory chain. The bc1 complex operates through a Q-cycle mechanism that couples electron transfer to generation of the proton gradient that drives ATP synthesis.
messages: Membrane

227882:SAVERM RS25210
gene id: 227882:SAVERM_RS25210
uniprot id: Q82DT2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

227882:SAVERM RS22965
gene id: 227882:SAVERM_RS22965
uniprot id: Q82F16
names: Subcellular Location Annotation
messages: Cytoplasm

227882:SAVERM RS31360
gene id: 227882:SAVERM_RS31360
uniprot id: Q82AG9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterioferritin family.
messages: Homooligomer of 24 subunits, arranged as 12 dimers, that are packed together to form an approximately spherical molecule with a central cavity, in which large amounts of iron can be deposited.
messages: Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex.

227882:SAVERM RS27155
gene id: 227882:SAVERM_RS27155
uniprot id: Q82CS8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-to-5' exoribonuclease specific for small oligoribonucleotides.
messages: Belongs to the oligoribonuclease family.
messages: Cytoplasm

227882:SAVERM RS12305
gene id: 227882:SAVERM_RS12305
uniprot id: Q82KL9
names: Function
names: Subcellular Location Annotation
messages: May play a structural or regulatory role in gas vesicle synthesis.
messages: Vesicle
messages: gas vesicle

227882:SAVERM RS10510
gene id: 227882:SAVERM_RS10510
uniprot id: Q82LL4
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. Allantoinase family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Carboxylation allows a single lysine to coordinate two zinc ions.
messages: Catalyzes the conversion of allantoin (5-ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring.
messages: Homotetramer.

227882:SAVERM RS36025
gene id: 227882:SAVERM_RS36025
uniprot id: Q827B3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

227882:SAVERM RS22055
gene id: 227882:SAVERM_RS22055
uniprot id: Q82FI7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

227882:SAVERM RS36595
gene id: 227882:SAVERM_RS36595
uniprot id: Q826Q2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CobB/CobQ family. GatD subfamily.
messages: Forms a heterodimer with MurT.
messages: The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The GatD subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia. The resulting ammonia molecule is channeled to the active site of MurT.

227882:SAVERM RS17760
gene id: 227882:SAVERM_RS17760
uniprot id: Q82HS5
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

227882:SAVERM RS32425
gene id: 227882:SAVERM_RS32425
uniprot id: Q829V6
names: Subcellular Location Annotation
messages: Membrane

227882:SAVERM RS05600
gene id: 227882:SAVERM_RS05600
uniprot id: Q79ZL1
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

227882:SAVERM RS25630
gene id: 227882:SAVERM_RS25630
uniprot id: Q82DK9
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

227882:SAVERM RS21370
gene id: 227882:SAVERM_RS21370
uniprot id: Q82FW4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

227882:SAVERM RS31070
gene id: 227882:SAVERM_RS31070
uniprot id: Q82AM7
names: Function
names: Similarity
messages: Belongs to the CobT family.
messages: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).

227882:SAVERM RS11305
gene id: 227882:SAVERM_RS11305
uniprot id: Q82L59
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

227882:SAVERM RS28230
gene id: 227882:SAVERM_RS28230
uniprot id: Q82C86
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

227882:SAVERM RS25300
gene id: 227882:SAVERM_RS25300
uniprot id: Q82DR8
names: Similarity
messages: Belongs to the UPF0336 family.

227882:SAVERM RS35440
gene id: 227882:SAVERM_RS35440
uniprot id: Q827M7
names: Subcellular Location Annotation
messages: Membrane

227882:SAVERM RS29040
gene id: 227882:SAVERM_RS29040
uniprot id: Q82BS6
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

227882:SAVERM RS35545
gene id: 227882:SAVERM_RS35545
uniprot id: Q827K5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

227882:SAVERM RS13880
gene id: 227882:SAVERM_RS13880
uniprot id: Q82JT8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

227882:SAVERM RS13435
gene id: 227882:SAVERM_RS13435
uniprot id: Q82K28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

227882:SAVERM RS33565
gene id: 227882:SAVERM_RS33565
uniprot id: Q828Y3
names: Similarity
messages: Belongs to the transglycosylase family. Rpf subfamily.

227882:SAVERM RS05255
gene id: 227882:SAVERM_RS05255
uniprot id: Q82PG7
names: Similarity
messages: Belongs to the thioesterase family.

227882:SAVERM RS36395
gene id: 227882:SAVERM_RS36395
uniprot id: Q826U1
names: Subcellular Location Annotation
messages: Membrane

227882:SAVERM RS09935
gene id: 227882:SAVERM_RS09935
uniprot id: Q82LX6
names: Function
names: Similarity
messages: Belongs to the gas vesicle protein type A family.
messages: Gas vesicles are small, hollow, gas filled protein structures that are found in several microbial planktonic microorganisms. They allow the positioning of the organism at the favorable depth for growth.

227882:SAVERM RS25375
gene id: 227882:SAVERM_RS25375
uniprot id: Q82DQ4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

227882:SAVERM RS03840
gene id: 227882:SAVERM_RS03840
uniprot id: Q82Q54
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

227882:SAVERM RS21275
gene id: 227882:SAVERM_RS21275
uniprot id: Q82FY0
names: Subcellular Location Annotation
messages: Membrane

227882:SAVERM RS10275
gene id: 227882:SAVERM_RS10275
uniprot id: Q82LR1
names: PTM
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.
messages: Carbamylation allows a single lysine to coordinate two divalent metal cations.

227882:SAVERM RS30265
gene id: 227882:SAVERM_RS30265
uniprot id: Q82B34
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

227882:SAVERM RS19795
gene id: 227882:SAVERM_RS19795
uniprot id: Q82GR6
names: Subcellular Location Annotation
messages: Membrane

227882:SAVERM RS13695
gene id: 227882:SAVERM_RS13695
uniprot id: Q82JX4
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

227882:SAVERM RS16735
gene id: 227882:SAVERM_RS16735
uniprot id: Q82IC6
names: Subcellular Location Annotation
messages: Cytoplasm

227882:SAVERM RS37575
gene id: 227882:SAVERM_RS37575
uniprot id: Q825X5
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

227882:SAVERM RS08585
gene id: 227882:SAVERM_RS08585
uniprot id: Q82MP0
names: Subcellular Location Annotation
messages: Membrane

227882:SAVERM RS22775
gene id: 227882:SAVERM_RS22775
uniprot id: Q82F57
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

227882:SAVERM RS34060
gene id: 227882:SAVERM_RS34060
uniprot id: Q828N3
names: Similarity
messages: Belongs to the gluconokinase GntK/GntV family.

227882:SAVERM RS37465
gene id: 227882:SAVERM_RS37465
uniprot id: Q825Z7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Catalyzes the production of L-lysyl-tRNA(Lys)transfer and the transfer of a lysyl group from L-lysyl-tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), one of the components of the bacterial membrane with a positive net charge. LPG synthesis contributes to the resistance to cationic antimicrobial peptides (CAMPs) and likely protects M.tuberculosis against the CAMPs produced by competiting microorganisms (bacteriocins). In fact, the modification of anionic phosphatidylglycerol with positively charged L-lysine results in repulsion of the peptides.
messages: Cell membrane
messages: Cytoplasm
messages: Homodimer.
messages: In the C-terminal section; belongs to the class-II aminoacyl-tRNA synthetase family.
messages: In the N-terminal section; belongs to the LPG synthetase family.
messages: Membrane

227882:SAVERM RS32535
gene id: 227882:SAVERM_RS32535
uniprot id: Q829T4
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

227882:SAVERM RS30655
gene id: 227882:SAVERM_RS30655
uniprot id: Q82AV8
names: Subcellular Location Annotation
messages: Membrane

227882:SAVERM RS18530
gene id: 227882:SAVERM_RS18530
uniprot id: Q82HC3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

227882:SAVERM RS01125
gene id: 227882:SAVERM_RS01125
uniprot id: Q82RK1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

227882:SAVERM RS14575
gene id: 227882:SAVERM_RS14575
uniprot id: Q82JF4
names: Similarity
messages: Belongs to the peptidase S8 family.

227882:SAVERM RS06315
gene id: 227882:SAVERM_RS06315
uniprot id: Q82NX6
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of adenosine and 2-deoxyadenosine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

227882:SAVERM RS24385
gene id: 227882:SAVERM_RS24385
uniprot id: Q82E91
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.

227882:SAVERM RS23085
gene id: 227882:SAVERM_RS23085
uniprot id: Q82EZ4
names: Subcellular Location Annotation
messages: Membrane

227882:SAVERM RS09540
gene id: 227882:SAVERM_RS09540
uniprot id: Q82M51
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M15D family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide.

227882:SAVERM RS31000
gene id: 227882:SAVERM_RS31000
uniprot id: Q82AP1
names: Subcellular Location Annotation
messages: Membrane

227882:SAVERM RS37235
gene id: 227882:SAVERM_RS37235
uniprot id: Q826E4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

227882:SAVERM RS12680
gene id: 227882:SAVERM_RS12680
uniprot id: Q82KH3
names: Subcellular Location Annotation
messages: Membrane

227882:SAVERM RS27965
gene id: 227882:SAVERM_RS27965
uniprot id: Q82CD3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Aliphatic sulfonates importer (TC 3.A.1.17.2) family.
messages: Cell membrane
messages: Part of the ABC transporter complex SsuABC involved in aliphatic sulfonates import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (SsuB), two transmembrane proteins (SsuC) and a solute-binding protein (SsuA).

227882:SAVERM RS35970
gene id: 227882:SAVERM_RS35970
uniprot id: Q827C4
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

227882:SAVERM RS01965
gene id: 227882:SAVERM_RS01965
uniprot id: Q82R44
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

227882:SAVERM RS13740
gene id: 227882:SAVERM_RS13740
uniprot id: Q82JW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

227882:SAVERM RS07220
gene id: 227882:SAVERM_RS07220
uniprot id: Q82NF3
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

227882:SAVERM RS07410
gene id: 227882:SAVERM_RS07410
uniprot id: Q82NB3
names: Similarity
messages: Belongs to the FAD-binding monooxygenase family.

227882:SAVERM RS13160
gene id: 227882:SAVERM_RS13160
uniprot id: Q82K82
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

227882:SAVERM RS38405
gene id: 227882:SAVERM_RS38405
uniprot id: Q825H8
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

227882:SAVERM RS37315
gene id: 227882:SAVERM_RS37315
uniprot id: Q826C8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

227882:SAVERM RS36790
gene id: 227882:SAVERM_RS36790
uniprot id: Q79Z21
names: Subunit
messages: Homodimer.

227882:SAVERM RS04470
gene id: 227882:SAVERM_RS04470
uniprot id: Q82PR9
names: Similarity
messages: Belongs to the phosphohexose mutase family.

227882:SAVERM RS28170
gene id: 227882:SAVERM_RS28170
uniprot id: Q82C98
names: Function
names: Similarity
messages: Belongs to the MreC family.
messages: Involved in formation and maintenance of cell shape.

227882:SAVERM RS21475
gene id: 227882:SAVERM_RS21475
uniprot id: Q82FU8
names: Subcellular Location Annotation
messages: Cytoplasm

227882:SAVERM RS05035
gene id: 227882:SAVERM_RS05035
uniprot id: Q82PJ1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

227882:SAVERM RS12280
gene id: 227882:SAVERM_RS12280
uniprot id: Q82KM4
names: Function
names: Subcellular Location Annotation
messages: May play a structural or regulatory role in gas vesicle synthesis.
messages: Vesicle
messages: gas vesicle

227882:SAVERM RS26650
gene id: 227882:SAVERM_RS26650
uniprot id: Q82D23
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

227882:SAVERM RS36985
gene id: 227882:SAVERM_RS36985
uniprot id: Q826J3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

227882:SAVERM RS13175
gene id: 227882:SAVERM_RS13175
uniprot id: Q82K79
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

227882:SAVERM RS33220
gene id: 227882:SAVERM_RS33220
uniprot id: Q829E9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

227882:SAVERM RS17910
gene id: 227882:SAVERM_RS17910
uniprot id: Q82HP4
names: Similarity
messages: Belongs to the peptidase C40 family.

227882:SAVERM RS23360
gene id: 227882:SAVERM_RS23360
uniprot id: Q82EU1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.

227882:SAVERM RS32680
gene id: 227882:SAVERM_RS32680
uniprot id: Q829Q5
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

227882:SAVERM RS37685
gene id: 227882:SAVERM_RS37685
uniprot id: Q79Z08
names: Function
names: Similarity
messages: Belongs to the EgtB family.
messages: Catalyzes the oxidative sulfurization of hercynine (N-alpha,N-alpha,N-alpha-trimethyl-L-histidine) into hercynyl-gamma-L-glutamyl-L-cysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine.

227882:SAVERM RS19010
gene id: 227882:SAVERM_RS19010
uniprot id: Q82H62
names: Similarity
messages: Belongs to the peptidase S58 family.

227882:SAVERM RS00975
gene id: 227882:SAVERM_RS00975
uniprot id: Q82RN4
names: Similarity
messages: Belongs to the cytochrome P450 family.

227882:SAVERM RS25225
gene id: 227882:SAVERM_RS25225
uniprot id: Q82DS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

227882:SAVERM RS31555
gene id: 227882:SAVERM_RS31555
uniprot id: Q82AD2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SepF family.
messages: Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
messages: Cytoplasm
messages: Homodimer. Interacts with FtsZ.

227882:SAVERM RS25870
gene id: 227882:SAVERM_RS25870
uniprot id: Q82DG6
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

227882:SAVERM RS22035
gene id: 227882:SAVERM_RS22035
uniprot id: Q82FJ1
names: Function
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: May catalyze the transamination reaction in phenylalanine biosynthesis.

227882:SAVERM RS25230
gene id: 227882:SAVERM_RS25230
uniprot id: Q82DS8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

227882:SAVERM RS32740
gene id: 227882:SAVERM_RS32740
uniprot id: Q829P3
names: Similarity
messages: Belongs to the DapA family.

227882:SAVERM RS19480
gene id: 227882:SAVERM_RS19480
uniprot id: Q82GX7
names: Similarity
messages: Belongs to the peptidase M1 family.

227882:SAVERM RS19920
gene id: 227882:SAVERM_RS19920
uniprot id: Q82GP1
names: Similarity
messages: Belongs to the UPF0309 family.

227882:SAVERM RS24210
gene id: 227882:SAVERM_RS24210
uniprot id: Q82EC5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

227882:SAVERM RS30780
gene id: 227882:SAVERM_RS30780
uniprot id: Q81ZW1
names: Function
names: Similarity
messages: Belongs to the GlnE family.
messages: Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell.

227882:SAVERM RS04430
gene id: 227882:SAVERM_RS04430
uniprot id: Q82PS8
names: Subcellular Location Annotation
messages: Membrane

227882:SAVERM RS29905
gene id: 227882:SAVERM_RS29905
uniprot id: Q82BA5
names: Function
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

227882:SAVERM RS04870
gene id: 227882:SAVERM_RS04870
uniprot id: Q82PM3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic Ku family.
messages: Homodimer. Interacts with LigD.
messages: With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD.

227882:SAVERM RS04585
gene id: 227882:SAVERM_RS04585
uniprot id: Q82PP6
names: Subcellular Location Annotation
messages: Cytoplasm

227882:SAVERM RS10245
gene id: 227882:SAVERM_RS10245
uniprot id: Q82LR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AmiS/UreI family.
messages: Membrane

227882:SAVERM RS19835
gene id: 227882:SAVERM_RS19835
uniprot id: Q82GQ8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

227882:SAVERM RS36185
gene id: 227882:SAVERM_RS36185
uniprot id: Q826Y2
names: Subcellular Location Annotation
messages: Membrane

227882:SAVERM RS08370
gene id: 227882:SAVERM_RS08370
uniprot id: Q82MT1
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

227882:SAVERM RS25015
gene id: 227882:SAVERM_RS25015
uniprot id: Q82DX0
names: Subcellular Location Annotation
messages: Membrane

227882:SAVERM RS11255
gene id: 227882:SAVERM_RS11255
uniprot id: Q82L68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

227882:SAVERM RS30145
gene id: 227882:SAVERM_RS30145
uniprot id: Q82B58
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Probably part of an ABC transporter complex. Responsible for energy coupling to the transport system (By similarity).

227882:SAVERM RS20395
gene id: 227882:SAVERM_RS20395
uniprot id: Q82GE5
names: Similarity
messages: Belongs to the peptidase M1 family.

227882:SAVERM RS09895
gene id: 227882:SAVERM_RS09895
uniprot id: Q82LY4
names: Similarity
messages: Belongs to the peptidase C56 family.

227882:SAVERM RS24280
gene id: 227882:SAVERM_RS24280
uniprot id: Q82EB1
names: Function
names: PTM
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system CseB/CseC involved in the stability of the cell envelope. CseB activates transcription of RNA polymerase sigma-E factor, in response to changes in the cell envelope (By similarity).
messages: Phosphorylated by CseC.

227882:SAVERM RS30685
gene id: 227882:SAVERM_RS30685
uniprot id: Q82AV2
names: Caution
names: Similarity
messages: Belongs to the globin family. Two-domain flavohemoproteins subfamily.
messages: In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

227882:SAVERM RS12840
gene id: 227882:SAVERM_RS12840
uniprot id: Q82KE1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

227882:SAVERM RS25455
gene id: 227882:SAVERM_RS25455
uniprot id: Q82DN9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

227882:SAVERM RS18230
gene id: 227882:SAVERM_RS18230
uniprot id: Q82HI0
names: Similarity
messages: Belongs to the CFA/CMAS family.

227882:SAVERM RS37460
gene id: 227882:SAVERM_RS37460
uniprot id: Q825Z8
names: Similarity
messages: Belongs to the universal stress protein A family.

227882:SAVERM RS29835
gene id: 227882:SAVERM_RS29835
uniprot id: Q82BB9
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

227882:SAVERM RS25520
gene id: 227882:SAVERM_RS25520
uniprot id: Q82DM7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

227882:SAVERM RS19855
gene id: 227882:SAVERM_RS19855
uniprot id: Q82GQ4
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

227882:SAVERM RS25345
gene id: 227882:SAVERM_RS25345
uniprot id: Q82DR0
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

227882:SAVERM RS16680
gene id: 227882:SAVERM_RS16680
uniprot id: Q82ID7
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

227882:SAVERM RS18405
gene id: 227882:SAVERM_RS18405
uniprot id: Q82HE7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

227882:SAVERM RS38325
gene id: 227882:SAVERM_RS38325
uniprot id: Q825J2
names: Similarity
messages: Belongs to the F420H(2)-dependent quinone reductase family.

227882:SAVERM RS24055
gene id: 227882:SAVERM_RS24055
uniprot id: Q82EF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Membrane

227882:SAVERM RS01360
gene id: 227882:SAVERM_RS01360
uniprot id: Q82RF8
names: Similarity
messages: Belongs to the GSP E family.

227882:SAVERM RS05480
gene id: 227882:SAVERM_RS05480
uniprot id: Q82PC6
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

227882:SAVERM RS27775
gene id: 227882:SAVERM_RS27775
uniprot id: Q82CH0
names: Cofactor
names: Similarity
messages: Belongs to the glycosyl hydrolase 4 family.
messages: Binds 1 NAD(+) per subunit.

227882:SAVERM RS09665
gene id: 227882:SAVERM_RS09665
uniprot id: Q82M28
names: Subcellular Location Annotation
messages: Membrane

227882:SAVERM RS10620
gene id: 227882:SAVERM_RS10620
uniprot id: Q82LJ2
names: Function
names: Similarity
messages: Belongs to the uricase family.
messages: Catalyzes the oxidation of uric acid to 5-hydroxyisourate, which is further processed to form (S)-allantoin.

227882:SAVERM RS25010
gene id: 227882:SAVERM_RS25010
uniprot id: Q82DX1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

227882:SAVERM RS20335
gene id: 227882:SAVERM_RS20335
uniprot id: Q82GF6
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

227882:SAVERM RS25515
gene id: 227882:SAVERM_RS25515
uniprot id: Q82DM8
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

227882:SAVERM RS17820
gene id: 227882:SAVERM_RS17820
uniprot id: Q82HR3
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.

227882:SAVERM RS27895
gene id: 227882:SAVERM_RS27895
uniprot id: Q82CE6
names: Similarity
messages: Belongs to the Nudix hydrolase family.

227882:SAVERM RS09405
gene id: 227882:SAVERM_RS09405
uniprot id: Q82M78
names: Subcellular Location Annotation
messages: Membrane

227882:SAVERM RS26035
gene id: 227882:SAVERM_RS26035
uniprot id: Q82DD2
names: Similarity
messages: Belongs to the PGI/PMI family.

227882:SAVERM RS27875
gene id: 227882:SAVERM_RS27875
uniprot id: Q82CF0
names: Similarity
messages: Belongs to the peptidase S8 family.

227882:SAVERM RS32960
gene id: 227882:SAVERM_RS32960
uniprot id: Q829K1
names: Subcellular Location Annotation
messages: Membrane

227882:SAVERM RS15560
gene id: 227882:SAVERM_RS15560
uniprot id: Q82IY8
names: Cofactor
names: Disruption Phenotype
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the FAD-binding monooxygenase family.
messages: Binds 1 FAD per subunit.
messages: Catalyzes the flavin-dependent Baeyer-Villiger oxidation of 1-deoxy-11-oxopentalenic acid to neopentalenolactone D in the biosynthesis of neopentalenolactone antibiotic.
messages: Cells lacking both ptlE and ptlD accumulate 1-deoxy-11-oxopentalenic acid.
messages: S.avermitilis does not produce pentalenolactone itself in vivo but instead a group of new metabolites that are neopentalenolactone derivatives.

227882:SAVERM RS12405
gene id: 227882:SAVERM_RS12405
uniprot id: Q79ZF5
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

227882:SAVERM RS22340
gene id: 227882:SAVERM_RS22340
uniprot id: Q82FD2
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

227882:SAVERM RS08940
gene id: 227882:SAVERM_RS08940
uniprot id: Q82MH0
names: Similarity
messages: Belongs to the DDAH family.

227882:SAVERM RS25315
gene id: 227882:SAVERM_RS25315
uniprot id: Q82DR5
names: Subcellular Location Annotation
messages: Membrane

227882:SAVERM RS33335
gene id: 227882:SAVERM_RS33335
uniprot id: Q829C5
names: Similarity
messages: Belongs to the DNA glycosylase MPG family.

227882:SAVERM RS27780
gene id: 227882:SAVERM_RS27780
uniprot id: Q82CG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

227882:SAVERM RS26710
gene id: 227882:SAVERM_RS26710
uniprot id: Q82D12
names: Subcellular Location Annotation
messages: Membrane

227882:SAVERM RS12750
gene id: 227882:SAVERM_RS12750
uniprot id: Q82KF9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

227882:SAVERM RS17845
gene id: 227882:SAVERM_RS17845
uniprot id: Q82HQ6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

227882:SAVERM RS26765
gene id: 227882:SAVERM_RS26765
uniprot id: Q82D02
names: Subcellular Location Annotation
messages: Membrane

227882:SAVERM RS36155
gene id: 227882:SAVERM_RS36155
uniprot id: Q826Y8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

227882:SAVERM RS23545
gene id: 227882:SAVERM_RS23545
uniprot id: Q82EQ7
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

227882:SAVERM RS15880
gene id: 227882:SAVERM_RS15880
uniprot id: Q82IS6
names: Similarity
messages: Belongs to the peptidase S16 family.

227882:SAVERM RS11820
gene id: 227882:SAVERM_RS11820
uniprot id: Q82KV6
names: Subcellular Location Annotation
messages: Cell membrane

227882:SAVERM RS10310
gene id: 227882:SAVERM_RS10310
uniprot id: Q82LQ4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

227882:SAVERM RS36480
gene id: 227882:SAVERM_RS36480
uniprot id: Q826S4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

227882:SAVERM RS13635
gene id: 227882:SAVERM_RS13635
uniprot id: Q82JY6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Fe(3+) ion importer (TC 3.A.1.10) family.
messages: Cell membrane
messages: Part of the ABC transporter complex FbpABC involved in Fe(3+) ions import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (FbpC), two transmembrane proteins (FbpB) and a solute-binding protein (FbpA).

227882:SAVERM RS24840
gene id: 227882:SAVERM_RS24840
uniprot id: Q82E03
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the radical SAM superfamily. MqnE family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3-[(1-carboxyvinyl)oxy]benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate.

227882:SAVERM RS18360
gene id: 227882:SAVERM_RS18360
uniprot id: Q82HF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

227882:SAVERM RS08535
gene id: 227882:SAVERM_RS08535
uniprot id: Q82MQ0
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

227882:SAVERM RS27760
gene id: 227882:SAVERM_RS27760
uniprot id: Q82CH3
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

227882:SAVERM RS36485
gene id: 227882:SAVERM_RS36485
uniprot id: Q826S3
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

227882:SAVERM RS25950
gene id: 227882:SAVERM_RS25950
uniprot id: Q82DF0
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

227882:SAVERM RS26270
gene id: 227882:SAVERM_RS26270
uniprot id: Q82D89
names: Similarity
messages: Belongs to the CDP-glycerol glycerophosphotransferase family.

227882:SAVERM RS29425
gene id: 227882:SAVERM_RS29425
uniprot id: Q82BK2
names: Subcellular Location Annotation
messages: Membrane

227882:SAVERM RS13870
gene id: 227882:SAVERM_RS13870
uniprot id: Q82JU0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

227882:SAVERM RS32890
gene id: 227882:SAVERM_RS32890
uniprot id: Q829L5
names: Function
names: Similarity
messages: Belongs to the ectoine synthase family.
messages: Catalyzes the circularization of gamma-N-acetyl-alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6-tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant.

227882:SAVERM RS30970
gene id: 227882:SAVERM_RS30970
uniprot id: Q82AP7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

227882:SAVERM RS17015
gene id: 227882:SAVERM_RS17015
uniprot id: Q82I71
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.
messages: Cytoplasm
messages: Monomer.

227882:SAVERM RS25255
gene id: 227882:SAVERM_RS25255
uniprot id: Q82DS3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

227882:SAVERM RS18965
gene id: 227882:SAVERM_RS18965
uniprot id: Q82H73
names: Similarity
messages: Belongs to the UDPGP type 2 family.

227882:SAVERM RS33210
gene id: 227882:SAVERM_RS33210
uniprot id: Q829F1
names: Similarity
messages: Belongs to the peptidase U62 family.

227882:SAVERM RS24155
gene id: 227882:SAVERM_RS24155
uniprot id: Q82ED6
names: Subcellular Location Annotation
messages: Mitochondrion

227882:SAVERM RS19805
gene id: 227882:SAVERM_RS19805
uniprot id: Q82GR4
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

227882:SAVERM RS32990
gene id: 227882:SAVERM_RS32990
uniprot id: Q829J5
names: Function
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.

227882:SAVERM RS09290
gene id: 227882:SAVERM_RS09290
uniprot id: Q82MA0
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

227882:SAVERM RS27515
gene id: 227882:SAVERM_RS27515
uniprot id: Q82CL5
names: Similarity
messages: Belongs to the citrate synthase family.

227882:SAVERM RS35110
gene id: 227882:SAVERM_RS35110
uniprot id: Q81ZV5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glutaminase PdxT/SNO family.
messages: Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.
messages: In the presence of PdxS, forms a dodecamer of heterodimers. Only shows activity in the heterodimer.

227882:SAVERM RS12010
gene id: 227882:SAVERM_RS12010
uniprot id: Q82KS5
names: Subcellular Location Annotation
messages: Membrane

227882:SAVERM RS15385
gene id: 227882:SAVERM_RS15385
uniprot id: Q82J23
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

227882:SAVERM RS19000
gene id: 227882:SAVERM_RS19000
uniprot id: Q82H65
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

227882:SAVERM RS33910
gene id: 227882:SAVERM_RS33910
uniprot id: Q828R3
names: Function
messages: TetR is the repressor of the tetracycline resistance element; its N-terminal region forms a helix-turn-helix structure and binds DNA. Binding of tetracycline to TetR reduces the repressor affinity for the tetracycline resistance gene (tetA) promoter operator sites.

227882:SAVERM RS25450
gene id: 227882:SAVERM_RS25450
uniprot id: Q82DP0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity).

227882:SAVERM RS19525
gene id: 227882:SAVERM_RS19525
uniprot id: Q82GW8
names: Similarity
messages: Belongs to the glutathione peroxidase family.

227882:SAVERM RS36500
gene id: 227882:SAVERM_RS36500
uniprot id: Q826S0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease beta subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

227882:SAVERM RS07040
gene id: 227882:SAVERM_RS07040
uniprot id: Q82NI8
names: Similarity
messages: Belongs to the class-II fumarase/aspartase family. Aspartase subfamily.

227882:SAVERM RS26380
gene id: 227882:SAVERM_RS26380
uniprot id: Q82D71
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

227882:SAVERM RS28280
gene id: 227882:SAVERM_RS28280
uniprot id: Q82C75
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

227882:SAVERM RS28700
gene id: 227882:SAVERM_RS28700
uniprot id: Q82BZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

227882:SAVERM RS16725
gene id: 227882:SAVERM_RS16725
uniprot id: Q82IC8
names: Subcellular Location Annotation
messages: Membrane

227882:SAVERM RS21405
gene id: 227882:SAVERM_RS21405
uniprot id: Q82FV9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

227882:SAVERM RS29815
gene id: 227882:SAVERM_RS29815
uniprot id: Q82BC3
names: Similarity
messages: Belongs to the aldose epimerase family.

227882:SAVERM RS09920
gene id: 227882:SAVERM_RS09920
uniprot id: Q82LX9
names: Function
names: Subcellular Location Annotation
messages: May play a structural or regulatory role in gas vesicle synthesis.
messages: Vesicle
messages: gas vesicle

227882:SAVERM RS37735
gene id: 227882:SAVERM_RS37735
uniprot id: Q825U9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

227882:SAVERM RS12415
gene id: 227882:SAVERM_RS12415
uniprot id: Q79ZF3
names: Similarity
messages: Belongs to the cytochrome P450 family.

227882:SAVERM RS22210
gene id: 227882:SAVERM_RS22210
uniprot id: Q82FF7
names: Similarity
messages: Belongs to the myo-inositol 1-phosphate synthase family.

227882:SAVERM RS08505
gene id: 227882:SAVERM_RS08505
uniprot id: Q82MQ6
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

227882:SAVERM RS35175
gene id: 227882:SAVERM_RS35175
uniprot id: Q827T0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

227882:SAVERM RS15775
gene id: 227882:SAVERM_RS15775
uniprot id: Q82IU5
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

227882:SAVERM RS17775
gene id: 227882:SAVERM_RS17775
uniprot id: Q82HS2
names: Activity Regulation
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 2 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate. Exhibits remarkably higher catalytic efficiency for oxaloacetate reduction than for malate oxidation in vitro. Highly specific for NAD(H). Can also use NADPH for oxaloacetate reduction, but catalytic efficiency is 97-fold higher with NADH. No activity detected with NADP(+) and malate.
messages: Strongly inhibited by Hg(2+) and Zn(2+). Activated by Na(+), NH(4)(+), Ca(2+), Cu(2+) and Mg(2+).

227882:SAVERM RS11765
gene id: 227882:SAVERM_RS11765
uniprot id: Q82KW7
names: Subcellular Location Annotation
messages: Membrane

227882:SAVERM RS19915
gene id: 227882:SAVERM_RS19915
uniprot id: Q82GP2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DtxR/MntR family.
messages: Cytoplasm
messages: Homodimer.

227882:SAVERM RS07965
gene id: 227882:SAVERM_RS07965
uniprot id: Q82N03
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

227882:SAVERM RS06330
gene id: 227882:SAVERM_RS06330
uniprot id: Q82NX3
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

227882:SAVERM RS30605
gene id: 227882:SAVERM_RS30605
uniprot id: Q82AW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Cell membrane
messages: Membrane

227882:SAVERM RS16480
gene id: 227882:SAVERM_RS16480
uniprot id: Q82IG5
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

227882:SAVERM RS19785
gene id: 227882:SAVERM_RS19785
uniprot id: Q82GR8
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

227882:SAVERM RS29070
gene id: 227882:SAVERM_RS29070
uniprot id: Q82BS0
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

227882:SAVERM RS13875
gene id: 227882:SAVERM_RS13875
uniprot id: Q82JT9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

227882:SAVERM RS36880
gene id: 227882:SAVERM_RS36880
uniprot id: Q79Z16
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

227882:SAVERM RS24895
gene id: 227882:SAVERM_RS24895
uniprot id: Q82DZ3
names: Similarity
messages: Belongs to the peptidase A24 family.

227882:SAVERM RS25555
gene id: 227882:SAVERM_RS25555
uniprot id: Q82DM3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

227882:SAVERM RS29760
gene id: 227882:SAVERM_RS29760
uniprot id: Q82BD4
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

227882:SAVERM RS10530
gene id: 227882:SAVERM_RS10530
uniprot id: Q82LL0
names: Similarity
messages: Belongs to the malate synthase family.

227882:SAVERM RS32340
gene id: 227882:SAVERM_RS32340
uniprot id: Q829X3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

227882:SAVERM RS00335
gene id: 227882:SAVERM_RS00335
uniprot id: Q82YB1
names: Similarity
messages: Belongs to the ParB family.

227882:SAVERM RS02765
gene id: 227882:SAVERM_RS02765
uniprot id: Q82QQ4
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

227882:SAVERM RS25600
gene id: 227882:SAVERM_RS25600
uniprot id: Q82DL5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic pantothenate kinase family.
messages: Cytoplasm

227882:SAVERM RS26945
gene id: 227882:SAVERM_RS26945
uniprot id: Q82CW7
names: Similarity
messages: Belongs to the peptidase C40 family.

227882:SAVERM RS38165
gene id: 227882:SAVERM_RS38165
uniprot id: Q825M1
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

227882:SAVERM RS21695
gene id: 227882:SAVERM_RS21695
uniprot id: Q82FQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Belongs to the glycosyltransferase 2 family.
messages: Membrane

227882:SAVERM RS14730
gene id: 227882:SAVERM_RS14730
uniprot id: Q82JC2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

227882:SAVERM RS26115
gene id: 227882:SAVERM_RS26115
uniprot id: Q82DC0
names: Function
names: Similarity
messages: Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).

227882:SAVERM RS26445
gene id: 227882:SAVERM_RS26445
uniprot id: Q82D58
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

227882:SAVERM RS04140
gene id: 227882:SAVERM_RS04140
uniprot id: Q82PZ0
names: Similarity
messages: Belongs to the darcynin family.

227882:SAVERM RS03965
gene id: 227882:SAVERM_RS03965
uniprot id: Q82Q27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

227882:SAVERM RS20505
gene id: 227882:SAVERM_RS20505
uniprot id: Q82GC4
names: Subcellular Location Annotation
messages: Cell membrane

227882:SAVERM RS14305
gene id: 227882:SAVERM_RS14305
uniprot id: Q82JK9
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

227882:SAVERM RS28185
gene id: 227882:SAVERM_RS28185
uniprot id: Q82C95
names: Subcellular Location Annotation
messages: Membrane

227882:SAVERM RS29480
gene id: 227882:SAVERM_RS29480
uniprot id: Q82BJ1
names: Similarity
messages: Belongs to the antibiotic N-acetyltransferase family.

227882:SAVERM RS15130
gene id: 227882:SAVERM_RS15130
uniprot id: Q82J69
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

227882:SAVERM RS08765
gene id: 227882:SAVERM_RS08765
uniprot id: Q82MK5
names: Similarity
messages: Belongs to the ABC transporter superfamily.

227882:SAVERM RS04565
gene id: 227882:SAVERM_RS04565
uniprot id: Q82PQ0
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.

227882:SAVERM RS06530
gene id: 227882:SAVERM_RS06530
uniprot id: Q82NS9
names: Similarity
messages: Belongs to the DNA photolyase family.

227882:SAVERM RS12955
gene id: 227882:SAVERM_RS12955
uniprot id: Q82KB8
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

227882:SAVERM RS02655
gene id: 227882:SAVERM_RS02655
uniprot id: Q82QT0
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

227882:SAVERM RS15000
gene id: 227882:SAVERM_RS15000
uniprot id: Q82J78
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

227882:SAVERM RS38075
gene id: 227882:SAVERM_RS38075
uniprot id: Q825N9
names: Subcellular Location Annotation
messages: Membrane

227882:SAVERM RS30440
gene id: 227882:SAVERM_RS30440
uniprot id: Q82B02
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

227882:SAVERM RS27460
gene id: 227882:SAVERM_RS27460
uniprot id: Q82CM5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Ribose importer (TC 3.A.1.2.1) family.
messages: Cell membrane
messages: Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system.
messages: The complex is composed of an ATP-binding protein (RbsA), two transmembrane proteins (RbsC) and a solute-binding protein (RbsB).

227882:SAVERM RS12905
gene id: 227882:SAVERM_RS12905
uniprot id: Q82KC8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Monomer.

227882:SAVERM RS15145
gene id: 227882:SAVERM_RS15145
uniprot id: Q82J66
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

227882:SAVERM RS09375
gene id: 227882:SAVERM_RS09375
uniprot id: Q82M84
names: Function
names: Similarity
messages: Belongs to the bacterial two-domain DSD family.
messages: Catalyzes the conversion of 3-dehydroshikimate to protocatechuate (3,4-dihydroxybenzoate), a common intermediate of quinate and shikimate degradation pathways.

227882:SAVERM RS06445
gene id: 227882:SAVERM_RS06445
uniprot id: Q82NU9
names: Subcellular Location Annotation
messages: Membrane

227882:SAVERM RS34525
gene id: 227882:SAVERM_RS34525
uniprot id: Q828E8
names: Subcellular Location Annotation
messages: Membrane

227882:SAVERM RS23485
gene id: 227882:SAVERM_RS23485
uniprot id: Q82ER8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial microcompartment
messages: Belongs to the EutC family.
messages: Binds between the large and small subunits.
messages: Catalyzes the deamination of various vicinal amino-alcohols to oxo compounds. Allows this organism to utilize ethanolamine as the sole source of nitrogen and carbon in the presence of external vitamin B12.
messages: The basic unit is a heterodimer which dimerizes to form tetramers. The heterotetramers trimerize; 6 large subunits form a core ring with 6 small subunits projecting outwards.

227882:SAVERM RS27175
gene id: 227882:SAVERM_RS27175
uniprot id: Q82CS4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetate uptake transporter (AceTr) (TC 2.A.96) family.
messages: Membrane

227882:SAVERM RS26000
gene id: 227882:SAVERM_RS26000
uniprot id: Q82DE0
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

227882:SAVERM RS25355
gene id: 227882:SAVERM_RS25355
uniprot id: Q82DQ8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

227882:SAVERM RS25395
gene id: 227882:SAVERM_RS25395
uniprot id: Q82DQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

227882:SAVERM RS13255
gene id: 227882:SAVERM_RS13255
uniprot id: Q82K63
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EccB family.
messages: Membrane

227882:SAVERM RS38940
gene id: 227882:SAVERM_RS38940
uniprot id: Q82PQ6
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

227882:SAVERM RS28255
gene id: 227882:SAVERM_RS28255
uniprot id: Q82C81
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

227882:SAVERM RS14930
gene id: 227882:SAVERM_RS14930
uniprot id: Q82J92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

227882:SAVERM RS20985
gene id: 227882:SAVERM_RS20985
uniprot id: Q82G25
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

227882:SAVERM RS11240
gene id: 227882:SAVERM_RS11240
uniprot id: Q82L71
names: Subcellular Location Annotation
messages: Membrane

227882:SAVERM RS24185
gene id: 227882:SAVERM_RS24185
uniprot id: Q82ED0
names: Similarity
messages: Belongs to the threonine aldolase family.

227882:SAVERM RS25710
gene id: 227882:SAVERM_RS25710
uniprot id: Q82DJ2
names: Similarity
messages: Belongs to the glycosyl hydrolase 10 (cellulase F) family.

227882:SAVERM RS16265
gene id: 227882:SAVERM_RS16265
uniprot id: Q82IJ5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the MshB deacetylase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deacetylation of 1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway.

227882:SAVERM RS12940
gene id: 227882:SAVERM_RS12940
uniprot id: Q82KC1
names: Subcellular Location Annotation
messages: Cell membrane

227882:SAVERM RS12685
gene id: 227882:SAVERM_RS12685
uniprot id: Q82KH2
names: Subcellular Location Annotation
messages: Cytoplasm

227882:SAVERM RS23600
gene id: 227882:SAVERM_RS23600
uniprot id: Q82EP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

227882:SAVERM RS37765
gene id: 227882:SAVERM_RS37765
uniprot id: Q825U3
names: Similarity
messages: Belongs to the pirin family.

227882:SAVERM RS31385
gene id: 227882:SAVERM_RS31385
uniprot id: Q82AG5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

227882:SAVERM RS15315
gene id: 227882:SAVERM_RS15315
uniprot id: Q82J37
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic Ku family.
messages: Homodimer. Interacts with LigD.
messages: With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD.

227882:SAVERM RS22025
gene id: 227882:SAVERM_RS22025
uniprot id: Q82FJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

227882:SAVERM RS31420
gene id: 227882:SAVERM_RS31420
uniprot id: Q82AF8
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

227882:SAVERM RS22150
gene id: 227882:SAVERM_RS22150
uniprot id: Q82FG8
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

227882:SAVERM RS11785
gene id: 227882:SAVERM_RS11785
uniprot id: Q82KW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

227882:SAVERM RS21665
gene id: 227882:SAVERM_RS21665
uniprot id: Q82FR2
names: Subcellular Location Annotation
messages: Membrane

227882:SAVERM RS13410
gene id: 227882:SAVERM_RS13410
uniprot id: Q82K33
names: Similarity
messages: Belongs to the glycosyl hydrolase 12 (cellulase H) family.

227882:SAVERM RS25800
gene id: 227882:SAVERM_RS25800
uniprot id: Q82DH5
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

227882:SAVERM RS02730
gene id: 227882:SAVERM_RS02730
uniprot id: Q82QR5
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

227882:SAVERM RS21225
gene id: 227882:SAVERM_RS21225
uniprot id: P59721
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.

227882:SAVERM RS19830
gene id: 227882:SAVERM_RS19830
uniprot id: Q82GQ9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

227882:SAVERM RS19570
gene id: 227882:SAVERM_RS19570
uniprot id: Q82GV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

227882:SAVERM RS08895
gene id: 227882:SAVERM_RS08895
uniprot id: Q82MH9
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

227882:SAVERM RS17455
gene id: 227882:SAVERM_RS17455
uniprot id: Q82HY3
names: Similarity
names: Subunit
messages: Belongs to the CMP-NeuNAc synthase family.
messages: Belongs to the KdsC family.
messages: Homotetramer.

227882:SAVERM RS11760
gene id: 227882:SAVERM_RS11760
uniprot id: Q82KW8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

227882:SAVERM RS08510
gene id: 227882:SAVERM_RS08510
uniprot id: Q82MQ5
names: Similarity
messages: Belongs to the Dps family.

227882:SAVERM RS36235
gene id: 227882:SAVERM_RS36235
uniprot id: Q826X2
names: Similarity
messages: Belongs to the IMPACT family.

227882:SAVERM RS14955
gene id: 227882:SAVERM_RS14955
uniprot id: Q82J87
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family. Chitinase class II subfamily.

227882:SAVERM RS35505
gene id: 227882:SAVERM_RS35505
uniprot id: Q827L4
names: Subcellular Location Annotation
messages: Membrane

227882:SAVERM RS06840
gene id: 227882:SAVERM_RS06840
uniprot id: Q82NM9
names: Similarity
messages: Belongs to the XFP family.

227882:SAVERM RS28815
gene id: 227882:SAVERM_RS28815
uniprot id: Q82BX0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

227882:SAVERM RS27535
gene id: 227882:SAVERM_RS27535
uniprot id: Q82CL1
names: Subcellular Location Annotation
messages: Membrane

227882:SAVERM RS13970
gene id: 227882:SAVERM_RS13970
uniprot id: Q82JS0
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

227882:SAVERM RS33145
gene id: 227882:SAVERM_RS33145
uniprot id: Q829G4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM86 family.
messages: Membrane

227882:SAVERM RS12375
gene id: 227882:SAVERM_RS12375
uniprot id: Q79ZG1
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

227882:SAVERM RS14985
gene id: 227882:SAVERM_RS14985
uniprot id: Q82J81
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

227882:SAVERM RS30555
gene id: 227882:SAVERM_RS30555
uniprot id: Q82AX9
names: Similarity
messages: Belongs to the EfeM/EfeO family.

227882:SAVERM RS12295
gene id: 227882:SAVERM_RS12295
uniprot id: Q82KM1
names: Function
names: Similarity
messages: Belongs to the histone H1/H5 family. HCT subfamily.
messages: Might have a role in establishing the nucleoid structure of elementary bodies.

227882:SAVERM RS34530
gene id: 227882:SAVERM_RS34530
uniprot id: Q828E7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

227882:SAVERM RS07290
gene id: 227882:SAVERM_RS07290
uniprot id: Q82ND8
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the nitrobindin family.
messages: Binds 1 heme b group per subunit, that coordinates a highly solvent-exposed Fe(III) atom.
messages: Forms a 10-stranded antiparallel beta-barrel structure able to accommodate a hydrophobic ligand in its interior. In fact, this fold hosts the heme group, which is located in a wide surface cleft.
messages: Heme-binding protein able to scavenge peroxynitrite and to protect free L-tyrosine against peroxynitrite-mediated nitration, by acting as a peroxynitrite isomerase that converts peroxynitrite to nitrate. Therefore, this protein likely plays a role in peroxynitrite sensing and in the detoxification of reactive nitrogen and oxygen species (RNS and ROS, respectively). Is able to bind nitric oxide (NO) in vitro, but may act as a sensor of peroxynitrite levels in vivo.
messages: Homodimer.

227882:SAVERM RS08715
gene id: 227882:SAVERM_RS08715
uniprot id: Q82ML5
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

227882:SAVERM RS11985
gene id: 227882:SAVERM_RS11985
uniprot id: Q82KT0
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

227882:SAVERM RS30065
gene id: 227882:SAVERM_RS30065
uniprot id: Q82B74
names: Subcellular Location Annotation
messages: Membrane

227882:SAVERM RS29210
gene id: 227882:SAVERM_RS29210
uniprot id: Q82BP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

227882:SAVERM RS13830
gene id: 227882:SAVERM_RS13830
uniprot id: Q82JU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

227882:SAVERM RS03995
gene id: 227882:SAVERM_RS03995
uniprot id: Q82Q21
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

227882:SAVERM RS37690
gene id: 227882:SAVERM_RS37690
uniprot id: Q825V6
names: Function
names: Similarity
messages: Belongs to the glutamate--cysteine ligase type 2 family. EgtA subfamily.
messages: Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC). This compound is used as substrate for the biosynthesis of the low-molecular thiol compound ergothioneine.

227882:SAVERM RS32460
gene id: 227882:SAVERM_RS32460
uniprot id: Q829U9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

227882:SAVERM RS17980
gene id: 227882:SAVERM_RS17980
uniprot id: Q82HM9
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

227882:SAVERM RS36445
gene id: 227882:SAVERM_RS36445
uniprot id: Q826T1
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

227882:SAVERM RS20755
gene id: 227882:SAVERM_RS20755
uniprot id: Q82G71
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

227882:SAVERM RS17365
gene id: 227882:SAVERM_RS17365
uniprot id: Q82I02
names: Subcellular Location Annotation
messages: Membrane

227882:SAVERM RS35190
gene id: 227882:SAVERM_RS35190
uniprot id: Q827S7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

227882:SAVERM RS24065
gene id: 227882:SAVERM_RS24065
uniprot id: Q82EF4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

227882:SAVERM RS25920
gene id: 227882:SAVERM_RS25920
uniprot id: Q82DF6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

227882:SAVERM RS31865
gene id: 227882:SAVERM_RS31865
uniprot id: Q82A68
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan.
messages: Belongs to the glycosyl hydrolase 46 family.
messages: Secreted

227882:SAVERM RS25725
gene id: 227882:SAVERM_RS25725
uniprot id: Q82DI9
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

227882:SAVERM RS34860
gene id: 227882:SAVERM_RS34860
uniprot id: Q827Y0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Methionine importer (TC 3.A.1.24) family.
messages: Cell membrane
messages: Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (MetN), two transmembrane proteins (MetI) and a solute-binding protein (MetQ).

227882:SAVERM RS18625
gene id: 227882:SAVERM_RS18625
uniprot id: Q82HA4
names: Subcellular Location Annotation
messages: Membrane

227882:SAVERM RS18975
gene id: 227882:SAVERM_RS18975
uniprot id: Q82H71
names: Cofactor
names: Similarity
messages: Belongs to the peptidase S45 family.
messages: Binds 1 Ca(2+) ion per dimer.

227882:SAVERM RS30130
gene id: 227882:SAVERM_RS30130
uniprot id: Q82B61
names: Similarity
messages: Belongs to the AB hydrolase superfamily. Lipase family.

227882:SAVERM RS25400
gene id: 227882:SAVERM_RS25400
uniprot id: Q82DQ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

227882:SAVERM RS21000
gene id: 227882:SAVERM_RS21000
uniprot id: Q82G22
names: Subcellular Location Annotation
messages: Membrane

227882:SAVERM RS16610
gene id: 227882:SAVERM_RS16610
uniprot id: Q82IF1
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

227882:SAVERM RS09660
gene id: 227882:SAVERM_RS09660
uniprot id: Q82M29
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

227882:SAVERM RS21375
gene id: 227882:SAVERM_RS21375
uniprot id: Q82FW3
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

227882:SAVERM RS33265
gene id: 227882:SAVERM_RS33265
uniprot id: Q829D9
names: Subcellular Location Annotation
messages: Membrane

227882:SAVERM RS35280
gene id: 227882:SAVERM_RS35280
uniprot id: Q827R0
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

227882:SAVERM RS32840
gene id: 227882:SAVERM_RS32840
uniprot id: Q829M5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Membrane

227882:SAVERM RS07745
gene id: 227882:SAVERM_RS07745
uniprot id: Q82N47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

227882:SAVERM RS33530
gene id: 227882:SAVERM_RS33530
uniprot id: Q828Z0
names: Similarity
messages: Belongs to the prephenate/arogenate dehydrogenase family.

227882:SAVERM RS20890
gene id: 227882:SAVERM_RS20890
uniprot id: Q82G46
names: Subcellular Location Annotation
messages: Membrane

227882:SAVERM RS29485
gene id: 227882:SAVERM_RS29485
uniprot id: Q82BJ0
names: Similarity
messages: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family.

227882:SAVERM RS30335
gene id: 227882:SAVERM_RS30335
uniprot id: Q82B22
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

227882:SAVERM RS04850
gene id: 227882:SAVERM_RS04850
uniprot id: Q82PM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S33 family.
messages: Cytoplasm

227882:SAVERM RS27660
gene id: 227882:SAVERM_RS27660
uniprot id: Q82CI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

227882:SAVERM RS25505
gene id: 227882:SAVERM_RS25505
uniprot id: Q82DN0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

227882:SAVERM RS32580
gene id: 227882:SAVERM_RS32580
uniprot id: Q829S4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

227882:SAVERM RS26025
gene id: 227882:SAVERM_RS26025
uniprot id: Q82DD5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lactate permease family.
messages: Cell membrane
messages: Membrane
messages: Uptake of L-lactate across the membrane. Can also transport D-lactate and glycolate.

227882:SAVERM RS36470
gene id: 227882:SAVERM_RS36470
uniprot id: Q826S6
names: Similarity
messages: Belongs to the peptidase C40 family.

227882:SAVERM RS16985
gene id: 227882:SAVERM_RS16985
uniprot id: Q82I77
names: Similarity
messages: Belongs to the DSD1 family.

227882:SAVERM RS29850
gene id: 227882:SAVERM_RS29850
uniprot id: Q82BB6
names: Similarity
messages: Belongs to the CdaR family.

227882:SAVERM RS28145
gene id: 227882:SAVERM_RS28145
uniprot id: Q82CA3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

227882:SAVERM RS26330
gene id: 227882:SAVERM_RS26330
uniprot id: Q82D80
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division.

227882:SAVERM RS14590
gene id: 227882:SAVERM_RS14590
uniprot id: Q82JF1
names: Similarity
names: Subunit
messages: Belongs to the aminoglycoside phosphotransferase family.
messages: Monomer.

227882:SAVERM RS30825
gene id: 227882:SAVERM_RS30825
uniprot id: Q82AS5
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

227882:SAVERM RS01035
gene id: 227882:SAVERM_RS01035
uniprot id: Q82RM0
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

227882:SAVERM RS28015
gene id: 227882:SAVERM_RS28015
uniprot id: Q82CC4
names: Similarity
messages: Belongs to the FPG family.

227882:SAVERM RS19740
gene id: 227882:SAVERM_RS19740
uniprot id: Q82GS6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

227882:SAVERM RS23515
gene id: 227882:SAVERM_RS23515
uniprot id: Q82ER2
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

227882:SAVERM RS06835
gene id: 227882:SAVERM_RS06835
uniprot id: Q82NN0
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

227882:SAVERM RS03945
gene id: 227882:SAVERM_RS03945
uniprot id: Q82Q29
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

227882:SAVERM RS28080
gene id: 227882:SAVERM_RS28080
uniprot id: Q82CB2
names: Similarity
messages: Belongs to the EccD/Snm4 family.

227882:SAVERM RS14065
gene id: 227882:SAVERM_RS14065
uniprot id: Q82JQ7
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

227882:SAVERM RS09595
gene id: 227882:SAVERM_RS09595
uniprot id: Q82M42
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

227882:SAVERM RS23860
gene id: 227882:SAVERM_RS23860
uniprot id: Q82EJ3
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

227882:SAVERM RS12665
gene id: 227882:SAVERM_RS12665
uniprot id: Q82KH6
names: Similarity
messages: Belongs to the citrate synthase family.

227882:SAVERM RS25360
gene id: 227882:SAVERM_RS25360
uniprot id: Q82DQ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

227882:SAVERM RS10625
gene id: 227882:SAVERM_RS10625
uniprot id: Q82LJ1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.
messages: Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU).
messages: Homotetramer.

227882:SAVERM RS37350
gene id: 227882:SAVERM_RS37350
uniprot id: Q826C1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

227882:SAVERM RS19965
gene id: 227882:SAVERM_RS19965
uniprot id: Q82GN2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

227882:SAVERM RS24900
gene id: 227882:SAVERM_RS24900
uniprot id: Q82DZ2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the radical SAM superfamily. MqnC family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2).

227882:SAVERM RS34875
gene id: 227882:SAVERM_RS34875
uniprot id: Q827X7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nlpA lipoprotein family.
messages: Membrane

227882:SAVERM RS35345
gene id: 227882:SAVERM_RS35345
uniprot id: Q827P7
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

227882:SAVERM RS07010
gene id: 227882:SAVERM_RS07010
uniprot id: Q82NJ5
names: Similarity
messages: Belongs to the cytochrome P450 family.

227882:SAVERM RS08260
gene id: 227882:SAVERM_RS08260
uniprot id: Q82MV3
names: Similarity
messages: Belongs to the UPF0047 family.

227882:SAVERM RS29270
gene id: 227882:SAVERM_RS29270
uniprot id: Q82BN0
names: Similarity
messages: Belongs to the dGTPase family. Type 2 subfamily.

227882:SAVERM RS13130
gene id: 227882:SAVERM_RS13130
uniprot id: Q82K88
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

227882:SAVERM RS17385
gene id: 227882:SAVERM_RS17385
uniprot id: Q82HZ8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

227882:SAVERM RS21700
gene id: 227882:SAVERM_RS21700
uniprot id: Q82FQ5
names: Subcellular Location Annotation
messages: Cell membrane

227882:SAVERM RS02545
gene id: 227882:SAVERM_RS02545
uniprot id: Q79ZT8
names: Similarity
messages: Belongs to the thioesterase family.

227882:SAVERM RS31305
gene id: 227882:SAVERM_RS31305
uniprot id: Q82AI0
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

227882:SAVERM RS23975
gene id: 227882:SAVERM_RS23975
uniprot id: Q82EH2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

227882:SAVERM RS06285
gene id: 227882:SAVERM_RS06285
uniprot id: Q82NY2
names: Subcellular Location Annotation
messages: Membrane

227882:SAVERM RS31510
gene id: 227882:SAVERM_RS31510
uniprot id: Q82AE0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

227882:SAVERM RS25215
gene id: 227882:SAVERM_RS25215
uniprot id: Q82DT1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

227882:SAVERM RS37020
gene id: 227882:SAVERM_RS37020
uniprot id: Q826I7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

227882:SAVERM RS36585
gene id: 227882:SAVERM_RS36585
uniprot id: Q826Q4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

227882:SAVERM RS19935
gene id: 227882:SAVERM_RS19935
uniprot id: Q82GN8
names: Similarity
messages: Belongs to the citrate synthase family.

227882:SAVERM RS13835
gene id: 227882:SAVERM_RS13835
uniprot id: Q82JU6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

227882:SAVERM RS25140
gene id: 227882:SAVERM_RS25140
uniprot id: Q82DU6
names: Similarity
messages: Belongs to the peptidase M28 family. M28A subfamily.

227882:SAVERM RS11185
gene id: 227882:SAVERM_RS11185
uniprot id: Q82L82
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.
messages: Cytoplasm

227882:SAVERM RS29055
gene id: 227882:SAVERM_RS29055
uniprot id: Q82BS3
names: Similarity
messages: Belongs to the Fur family.

227882:SAVERM RS15700
gene id: 227882:SAVERM_RS15700
uniprot id: Q82IW0
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Global regulator that is part of the nutrient-sensing system. In the absence of glucosamine 6-P (GlcN6P), represses the phosphotransferase system (PTS) specific for the uptake of N-acetylglucosamine (PTSNag), and genes involved in the metabolism of chitin, as well as several genes involved in development, thereby linking carbon availability to morphogenesis.

227882:SAVERM RS29000
gene id: 227882:SAVERM_RS29000
uniprot id: Q82BT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

227882:SAVERM RS35580
gene id: 227882:SAVERM_RS35580
uniprot id: Q827J8
names: Subcellular Location Annotation
messages: Membrane

227882:SAVERM RS38005
gene id: 227882:SAVERM_RS38005
uniprot id: Q825Q3
names: Subcellular Location Annotation
messages: Membrane

227882:SAVERM RS16095
gene id: 227882:SAVERM_RS16095
uniprot id: Q82IN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Membrane

227882:SAVERM RS24470
gene id: 227882:SAVERM_RS24470
uniprot id: Q82E78
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transcriptional regulatory Rex family.
messages: Cytoplasm
messages: Homodimer.
messages: Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.

227882:SAVERM RS23790
gene id: 227882:SAVERM_RS23790
uniprot id: Q82EK8
names: Similarity
messages: Belongs to the GSP E family.

227882:SAVERM RS13725
gene id: 227882:SAVERM_RS13725
uniprot id: Q82JW8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

227882:SAVERM RS01145
gene id: 227882:SAVERM_RS01145
uniprot id: Q82RJ8
names: Subcellular Location Annotation
messages: Membrane

227882:SAVERM RS24485
gene id: 227882:SAVERM_RS24485
uniprot id: Q82E75
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

227882:SAVERM RS15160
gene id: 227882:SAVERM_RS15160
uniprot id: Q82J63
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

227882:SAVERM RS10140
gene id: 227882:SAVERM_RS10140
uniprot id: Q82LT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

227882:SAVERM RS14315
gene id: 227882:SAVERM_RS14315
uniprot id: Q82JK7
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

227882:SAVERM RS11290
gene id: 227882:SAVERM_RS11290
uniprot id: Q82L61
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

227882:SAVERM RS30810
gene id: 227882:SAVERM_RS30810
uniprot id: Q82AS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

227882:SAVERM RS36535
gene id: 227882:SAVERM_RS36535
uniprot id: Q826R3
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

227882:SAVERM RS14155
gene id: 227882:SAVERM_RS14155
uniprot id: Q82JN9
names: Cofactor
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
messages: Binds 2 nickel ions per subunit.
messages: Carboxylation allows a single lysine to coordinate two nickel ions.
messages: Cytoplasm
messages: May form a heterohexamer of 3 UreC (alpha) and 3 UreAB (gamma/beta) subunits. May also form a heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

227882:SAVERM RS08945
gene id: 227882:SAVERM_RS08945
uniprot id: Q82MG9
names: Cofactor
names: Similarity
messages: Belongs to the fatty acid desaturase type 2 family.
messages: Binds 2 iron ions per subunit.

227882:SAVERM RS08065
gene id: 227882:SAVERM_RS08065
uniprot id: Q82MY3
names: Similarity
messages: Belongs to the ACC deaminase/D-cysteine desulfhydrase family.

227882:SAVERM RS26045
gene id: 227882:SAVERM_RS26045
uniprot id: Q82DD0
names: Subcellular Location Annotation
messages: Membrane

227882:SAVERM RS14445
gene id: 227882:SAVERM_RS14445
uniprot id: Q82JI0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.

227882:SAVERM RS33165
gene id: 227882:SAVERM_RS33165
uniprot id: Q829G0
names: Similarity
messages: Belongs to the peptidase S8 family.

227882:SAVERM RS30545
gene id: 227882:SAVERM_RS30545
uniprot id: Q82AY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oxidase-dependent Fe transporter (OFeT) (TC 9.A.10.1) family.
messages: Membrane

227882:SAVERM RS33625
gene id: 227882:SAVERM_RS33625
uniprot id: Q828X0
names: Subcellular Location Annotation
messages: Membrane

227882:SAVERM RS25365
gene id: 227882:SAVERM_RS25365
uniprot id: Q82DQ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

227882:SAVERM RS33985
gene id: 227882:SAVERM_RS33985
uniprot id: Q828P8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

227882:SAVERM RS25425
gene id: 227882:SAVERM_RS25425
uniprot id: Q82DP5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

227882:SAVERM RS11995
gene id: 227882:SAVERM_RS11995
uniprot id: Q82KS8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.

227882:SAVERM RS13290
gene id: 227882:SAVERM_RS13290
uniprot id: Q82K56
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

227882:SAVERM RS32900
gene id: 227882:SAVERM_RS32900
uniprot id: Q829L3
names: Function
names: Similarity
messages: Belongs to the acetyltransferase family. EctA subfamily.
messages: Catalyzes the acetylation of L-2,4-diaminobutyrate (DABA) to gamma-N-acetyl-alpha,gamma-diaminobutyric acid (ADABA) with acetyl coenzyme A.

227882:SAVERM RS22245
gene id: 227882:SAVERM_RS22245
uniprot id: Q82FF0
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

227882:SAVERM RS32375
gene id: 227882:SAVERM_RS32375
uniprot id: Q829W6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gluconeogenesis factor family.
messages: Cytoplasm
messages: Required for morphogenesis under gluconeogenic growth conditions.

227882:SAVERM RS37525
gene id: 227882:SAVERM_RS37525
uniprot id: Q825Y4
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

227882:SAVERM RS26670
gene id: 227882:SAVERM_RS26670
uniprot id: Q82D19
names: Subcellular Location Annotation
messages: Membrane

227882:SAVERM RS05300
gene id: 227882:SAVERM_RS05300
uniprot id: Q82PF8
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

227882:SAVERM RS13295
gene id: 227882:SAVERM_RS13295
uniprot id: Q82K55
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

227882:SAVERM RS15940
gene id: 227882:SAVERM_RS15940
uniprot id: Q82IR3
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: Nucleus
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

227882:SAVERM RS19605
gene id: 227882:SAVERM_RS19605
uniprot id: Q82GV2
names: Cofactor
names: Function
names: Similarity
messages: Binds 2 [4Fe-4S] clusters. The clusters are coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated synthesis of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (FO) from 5-amino-6-(D-ribitylamino)uracil and L-tyrosine.
messages: In the C-terminal section; belongs to the radical SAM superfamily. CofH family.
messages: In the N-terminal section; belongs to the radical SAM superfamily. CofG family.

227882:SAVERM RS28935
gene id: 227882:SAVERM_RS28935
uniprot id: Q82BU7
names: Similarity
messages: Belongs to the DapA family.

227882:SAVERM RS31560
gene id: 227882:SAVERM_RS31560
uniprot id: Q82AD1
names: Similarity
messages: Belongs to the YggT family.

227882:SAVERM RS07575
gene id: 227882:SAVERM_RS07575
uniprot id: Q82N81
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell membrane
messages: Membrane

227882:SAVERM RS28020
gene id: 227882:SAVERM_RS28020
uniprot id: Q82CC3
names: Similarity
names: Subunit
messages: Belongs to the acetyltransferase Eis family.
messages: Homohexamer; trimer of dimers.

227882:SAVERM RS23170
gene id: 227882:SAVERM_RS23170
uniprot id: Q82EX7
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

227882:SAVERM RS27205
gene id: 227882:SAVERM_RS27205
uniprot id: Q79Z46
names: Function
messages: Acyltransferase required for the direct transfer of medium- to long-chain fatty acyl moieties from a carrier protein (MbtL) on to the epsilon-amino group of lysine residue in the mycobactin core.

227882:SAVERM RS07730
gene id: 227882:SAVERM_RS07730
uniprot id: Q82N50
names: Similarity
messages: Belongs to the glycosyl hydrolase 39 family.

227882:SAVERM RS22860
gene id: 227882:SAVERM_RS22860
uniprot id: Q82F38
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

227882:SAVERM RS03405
gene id: 227882:SAVERM_RS03405
uniprot id: Q82QC8
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

227882:SAVERM RS06440
gene id: 227882:SAVERM_RS06440
uniprot id: Q82NV0
names: Subcellular Location Annotation
messages: Membrane

227882:SAVERM RS04835
gene id: 227882:SAVERM_RS04835
uniprot id: Q82PN0
names: Similarity
messages: Belongs to the shaker potassium channel beta subunit family.

227882:SAVERM RS34305
gene id: 227882:SAVERM_RS34305
uniprot id: Q828J3
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

227882:SAVERM RS21425
gene id: 227882:SAVERM_RS21425
uniprot id: Q82FV6
names: Similarity
messages: Belongs to the SAICAR synthetase family.

227882:SAVERM RS37450
gene id: 227882:SAVERM_RS37450
uniprot id: Q826A0
names: Similarity
messages: Belongs to the CapA family.

227882:SAVERM RS14515
gene id: 227882:SAVERM_RS14515
uniprot id: Q82JG6
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

227882:SAVERM RS35305
gene id: 227882:SAVERM_RS35305
uniprot id: Q827Q5
names: Similarity
messages: Belongs to the OMP decarboxylase family. Type 2 subfamily.

227882:SAVERM RS06640
gene id: 227882:SAVERM_RS06640
uniprot id: Q82NQ8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Gfo/Idh/MocA family.
messages: Homotetramer.
messages: Involved in the oxidation of myo-inositol (MI) to 2-keto-myo-inositol (2KMI or 2-inosose).

227882:SAVERM RS12885
gene id: 227882:SAVERM_RS12885
uniprot id: Q82KD2
names: Similarity
messages: Belongs to the peptidase M1 family.

227882:SAVERM RS14160
gene id: 227882:SAVERM_RS14160
uniprot id: Q82JN8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterohexamer of 3 UreC (alpha) and 3 UreAB (gamma/beta) subunits.
messages: In the C-terminal section; belongs to the urease beta subunit family.
messages: In the N-terminal section; belongs to the urease gamma subunit family.

227882:SAVERM RS25325
gene id: 227882:SAVERM_RS25325
uniprot id: Q82DR3
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.

227882:SAVERM RS24110
gene id: 227882:SAVERM_RS24110
uniprot id: Q82EE5
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

227882:SAVERM RS17295
gene id: 227882:SAVERM_RS17295
uniprot id: Q82I16
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: Homotrimer.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. Cleaves guanosine, inosine, 2'-deoxyguanosine and 2'-deoxyinosine.

227882:SAVERM RS20865
gene id: 227882:SAVERM_RS20865
uniprot id: Q82G50
names: Subcellular Location Annotation
messages: Cell membrane

227882:SAVERM RS09735
gene id: 227882:SAVERM_RS09735
uniprot id: Q82M15
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

227882:SAVERM RS13595
gene id: 227882:SAVERM_RS13595
uniprot id: Q82JZ4
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

227882:SAVERM RS11280
gene id: 227882:SAVERM_RS11280
uniprot id: Q82L63
names: Cofactor
names: PTM
names: Similarity
messages: Belongs to the copper/topaquinone oxidase family.
messages: Contains 1 topaquinone per subunit.
messages: Topaquinone (TPQ) is generated by copper-dependent autoxidation of a specific tyrosyl residue.

227882:SAVERM RS07165
gene id: 227882:SAVERM_RS07165
uniprot id: Q82NG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

227882:SAVERM RS38020
gene id: 227882:SAVERM_RS38020
uniprot id: Q825Q0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

227882:SAVERM RS24815
gene id: 227882:SAVERM_RS24815
uniprot id: Q82E08
names: Subcellular Location Annotation
messages: Membrane

227882:SAVERM RS12600
gene id: 227882:SAVERM_RS12600
uniprot id: Q82KI9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.

227882:SAVERM RS36735
gene id: 227882:SAVERM_RS36735
uniprot id: Q826N0
names: Subcellular Location Annotation
messages: Membrane

227882:SAVERM RS18425
gene id: 227882:SAVERM_RS18425
uniprot id: Q82HE3
names: Function
names: Similarity
messages: Belongs to the PEPCase type 1 family.
messages: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.

227882:SAVERM RS30660
gene id: 227882:SAVERM_RS30660
uniprot id: Q82AV7
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

227882:SAVERM RS36780
gene id: 227882:SAVERM_RS36780
uniprot id: Q826M2
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

227882:SAVERM RS32600
gene id: 227882:SAVERM_RS32600
uniprot id: Q829S0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type 2 tetrahydrodipicolinate N-succinyltransferase family.
messages: Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2-amino-6-oxopimelate using succinyl-CoA.
messages: Cytoplasm
messages: Homotrimer.

227882:SAVERM RS20310
gene id: 227882:SAVERM_RS20310
uniprot id: Q82GG1
names: Similarity
messages: Belongs to the glycosyltransferase 20 family.

227882:SAVERM RS22185
gene id: 227882:SAVERM_RS22185
uniprot id: Q82FG2
names: Similarity
messages: Belongs to the FemABX family.

227882:SAVERM RS32295
gene id: 227882:SAVERM_RS32295
uniprot id: Q829Y2
names: Subcellular Location Annotation
messages: Membrane

227882:SAVERM RS32750
gene id: 227882:SAVERM_RS32750
uniprot id: Q829P1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

227882:SAVERM RS21350
gene id: 227882:SAVERM_RS21350
uniprot id: Q82FW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

227882:SAVERM RS22165
gene id: 227882:SAVERM_RS22165
uniprot id: P66471
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

227882:SAVERM RS04500
gene id: 227882:SAVERM_RS04500
uniprot id: Q82PR2
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

227882:SAVERM RS25915
gene id: 227882:SAVERM_RS25915
uniprot id: Q82DF7
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

227882:SAVERM RS34890
gene id: 227882:SAVERM_RS34890
uniprot id: Q827X4
names: Function
names: Similarity
messages: Belongs to the CobT family.
messages: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).

227882:SAVERM RS33490
gene id: 227882:SAVERM_RS33490
uniprot id: Q828Z8
names: Similarity
messages: Belongs to the Nudix hydrolase family.

227882:SAVERM RS25790
gene id: 227882:SAVERM_RS25790
uniprot id: Q82DH7
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

227882:SAVERM RS25475
gene id: 227882:SAVERM_RS25475
uniprot id: Q82DN5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

227882:SAVERM RS35365
gene id: 227882:SAVERM_RS35365
uniprot id: Q827P3
names: Similarity
messages: Belongs to the SorC transcriptional regulatory family.

227882:SAVERM RS10550
gene id: 227882:SAVERM_RS10550
uniprot id: Q82LK6
names: Similarity
messages: Belongs to the IucA/IucC family.

227882:SAVERM RS24295
gene id: 227882:SAVERM_RS24295
uniprot id: Q82EA8
names: Similarity
messages: Belongs to the Nth/MutY family.

227882:SAVERM RS09280
gene id: 227882:SAVERM_RS09280
uniprot id: Q82MA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

227882:SAVERM RS14695
gene id: 227882:SAVERM_RS14695
uniprot id: Q82JD0
names: Similarity
names: Subunit
messages: Belongs to the pyruvate kinase family.
messages: Homotetramer.

227882:SAVERM RS24050
gene id: 227882:SAVERM_RS24050
uniprot id: Q82EF7
names: Similarity
messages: Belongs to the UPF0145 family.

227882:SAVERM RS31585
gene id: 227882:SAVERM_RS31585
uniprot id: Q82AC6
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

227882:SAVERM RS22715
gene id: 227882:SAVERM_RS22715
uniprot id: Q82F68
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
messages: Cytoplasm
messages: Homodimer.

227882:SAVERM RS34895
gene id: 227882:SAVERM_RS34895
uniprot id: Q827X3
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

227882:SAVERM RS32690
gene id: 227882:SAVERM_RS32690
uniprot id: Q829Q3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

227882:SAVERM RS24080
gene id: 227882:SAVERM_RS24080
uniprot id: Q82EF1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

227882:SAVERM RS13380
gene id: 227882:SAVERM_RS13380
uniprot id: Q82K39
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

227882:SAVERM RS12990
gene id: 227882:SAVERM_RS12990
uniprot id: Q82KB1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

227882:SAVERM RS26200
gene id: 227882:SAVERM_RS26200
uniprot id: Q82DA3
names: Similarity
messages: Belongs to the CDP-glycerol glycerophosphotransferase family.

227882:SAVERM RS37600
gene id: 227882:SAVERM_RS37600
uniprot id: Q825X0
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

227882:SAVERM RS03750
gene id: 227882:SAVERM_RS03750
uniprot id: Q82Q72
names: Similarity
messages: Belongs to the gluconokinase GntK/GntV family.

227882:SAVERM RS24420
gene id: 227882:SAVERM_RS24420
uniprot id: Q82E88
names: Subcellular Location Annotation
messages: Membrane

227882:SAVERM RS12960
gene id: 227882:SAVERM_RS12960
uniprot id: Q82KB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

227882:SAVERM RS11990
gene id: 227882:SAVERM_RS11990
uniprot id: Q82KS9
names: Subcellular Location Annotation
messages: Membrane

227882:SAVERM RS17575
gene id: 227882:SAVERM_RS17575
uniprot id: Q82HW1
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.

227882:SAVERM RS34825
gene id: 227882:SAVERM_RS34825
uniprot id: Q827Y7
names: Subcellular Location Annotation
messages: Membrane

227882:SAVERM RS24995
gene id: 227882:SAVERM_RS24995
uniprot id: Q82DX4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

227882:SAVERM RS28335
gene id: 227882:SAVERM_RS28335
uniprot id: Q82C66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

227882:SAVERM RS27125
gene id: 227882:SAVERM_RS27125
uniprot id: Q82CT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

227882:SAVERM RS15495
gene id: 227882:SAVERM_RS15495
uniprot id: Q82J01
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

227882:SAVERM RS10290
gene id: 227882:SAVERM_RS10290
uniprot id: Q82LQ8
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

227882:SAVERM RS05925
gene id: 227882:SAVERM_RS05925
uniprot id: Q82P48
names: Subcellular Location Annotation
messages: Cell membrane

227882:SAVERM RS15570
gene id: 227882:SAVERM_RS15570
uniprot id: Q82IY5
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

227882:SAVERM RS23345
gene id: 227882:SAVERM_RS23345
uniprot id: Q82EU4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the spermidine/spermine synthase family.
messages: Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
messages: Cell membrane
messages: Homodimer or homotetramer.

227882:SAVERM RS10985
gene id: 227882:SAVERM_RS10985
uniprot id: Q82LC1
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

227882:SAVERM RS35330
gene id: 227882:SAVERM_RS35330
uniprot id: Q827Q0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

227882:SAVERM RS32380
gene id: 227882:SAVERM_RS32380
uniprot id: Q829W5
names: Function
names: Similarity
messages: Belongs to the WhiA family.
messages: Involved in cell division and chromosome segregation.

227882:SAVERM RS37355
gene id: 227882:SAVERM_RS37355
uniprot id: Q826C0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

227882:SAVERM RS12310
gene id: 227882:SAVERM_RS12310
uniprot id: Q82KL8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gas vesicle protein type A family.
messages: Gas vesicles are small, hollow, gas filled protein structures that are found in several microbial planktonic microorganisms. They allow the positioning of the organism at the favorable depth for growth. GvpA type proteins form the essential core of the structure.
messages: gas vesicle membrane

227882:SAVERM RS35540
gene id: 227882:SAVERM_RS35540
uniprot id: Q827K6
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family.

227882:SAVERM RS33180
gene id: 227882:SAVERM_RS33180
uniprot id: Q829F7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

227882:SAVERM RS37165
gene id: 227882:SAVERM_RS37165
uniprot id: Q826F8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

227882:SAVERM RS35475
gene id: 227882:SAVERM_RS35475
uniprot id: Q827M0
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

227882:SAVERM RS35760
gene id: 227882:SAVERM_RS35760
uniprot id: Q827G2
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

227882:SAVERM RS09990
gene id: 227882:SAVERM_RS09990
uniprot id: Q82LW5
names: Similarity
messages: Belongs to the arginase family.

227882:SAVERM RS26050
gene id: 227882:SAVERM_RS26050
uniprot id: Q82DC9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

227882:SAVERM RS25620
gene id: 227882:SAVERM_RS25620
uniprot id: Q82DL1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

227882:SAVERM RS26985
gene id: 227882:SAVERM_RS26985
uniprot id: Q82CW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

227882:SAVERM RS26690
gene id: 227882:SAVERM_RS26690
uniprot id: Q82D15
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

227882:SAVERM RS32955
gene id: 227882:SAVERM_RS32955
uniprot id: Q829K2
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

227882:SAVERM RS09640
gene id: 227882:SAVERM_RS09640
uniprot id: Q82M33
names: Subcellular Location Annotation
messages: Membrane

227882:SAVERM RS11755
gene id: 227882:SAVERM_RS11755
uniprot id: Q82KW9
names: Subcellular Location Annotation
messages: Membrane

227882:SAVERM RS04425
gene id: 227882:SAVERM_RS04425
uniprot id: Q82PS9
names: Subcellular Location Annotation
messages: Membrane

227882:SAVERM RS18685
gene id: 227882:SAVERM_RS18685
uniprot id: Q82H92
names: Subcellular Location Annotation
messages: Membrane

227882:SAVERM RS17350
gene id: 227882:SAVERM_RS17350
uniprot id: Q82I05
names: Subcellular Location Annotation
messages: Cell membrane

227882:SAVERM RS08290
gene id: 227882:SAVERM_RS08290
uniprot id: Q82MU7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase MltG family.
messages: Cell membrane
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

227882:SAVERM RS06225
gene id: 227882:SAVERM_RS06225
uniprot id: Q82NZ3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.
messages: Gly-125 is present instead of the conserved His which is expected to be an active site residue.

227882:SAVERM RS08785
gene id: 227882:SAVERM_RS08785
uniprot id: Q82MK1
names: Cofactor
messages: Binds 1 zinc ion per subunit.

227882:SAVERM RS09120
gene id: 227882:SAVERM_RS09120
uniprot id: Q82MD4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

227882:SAVERM RS21525
gene id: 227882:SAVERM_RS21525
uniprot id: Q82FT8
names: Similarity
messages: Belongs to the ice-binding protein family.

227882:SAVERM RS13950
gene id: 227882:SAVERM_RS13950
uniprot id: Q82JS4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

227882:SAVERM RS25615
gene id: 227882:SAVERM_RS25615
uniprot id: Q82DL2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

227882:SAVERM RS26040
gene id: 227882:SAVERM_RS26040
uniprot id: Q82DD1
names: Cofactor
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 1 family.
messages: Binds 1 zinc ion per subunit.

227882:SAVERM RS03240
gene id: 227882:SAVERM_RS03240
uniprot id: Q82QF8
names: Similarity
messages: Belongs to the DyP-type peroxidase family.

227882:SAVERM RS29175
gene id: 227882:SAVERM_RS29175
uniprot id: Q82BP9
names: Subcellular Location Annotation
messages: Cell membrane

227882:SAVERM RS32045
gene id: 227882:SAVERM_RS32045
uniprot id: Q82A33
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

227882:SAVERM RS18030
gene id: 227882:SAVERM_RS18030
uniprot id: Q82HL9
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

227882:SAVERM RS10835
gene id: 227882:SAVERM_RS10835
uniprot id: Q82LE9
names: Similarity
messages: Belongs to the cytochrome P450 family.

227882:SAVERM RS08555
gene id: 227882:SAVERM_RS08555
uniprot id: Q82MP6
names: Subcellular Location Annotation
messages: Membrane

227882:SAVERM RS19400
gene id: 227882:SAVERM_RS19400
uniprot id: Q82GZ2
names: Similarity
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.

227882:SAVERM RS16635
gene id: 227882:SAVERM_RS16635
uniprot id: Q82IE6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

227882:SAVERM RS24990
gene id: 227882:SAVERM_RS24990
uniprot id: Q82DX5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the complex I 75 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

227882:SAVERM RS16380
gene id: 227882:SAVERM_RS16380
uniprot id: Q79ZA3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

227882:SAVERM RS19615
gene id: 227882:SAVERM_RS19615
uniprot id: Q82GV0
names: Similarity
messages: Belongs to the F420H(2)-dependent quinone reductase family.

227882:SAVERM RS35275
gene id: 227882:SAVERM_RS35275
uniprot id: Q827R1
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

227882:SAVERM RS25530
gene id: 227882:SAVERM_RS25530
uniprot id: Q82DM5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Monomer.

227882:SAVERM RS09170
gene id: 227882:SAVERM_RS09170
uniprot id: Q82MC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

227882:SAVERM RS34500
gene id: 227882:SAVERM_RS34500
uniprot id: Q828F3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

227882:SAVERM RS04940
gene id: 227882:SAVERM_RS04940
uniprot id: Q82PK9
names: Subcellular Location Annotation
messages: Cytoplasm

227882:SAVERM RS26515
gene id: 227882:SAVERM_RS26515
uniprot id: Q82D45
names: Subcellular Location Annotation
messages: Membrane

227882:SAVERM RS35485
gene id: 227882:SAVERM_RS35485
uniprot id: Q827L8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA-PH family.
messages: Cytoplasm

227882:SAVERM RS15715
gene id: 227882:SAVERM_RS15715
uniprot id: Q82IV7
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

227882:SAVERM RS12095
gene id: 227882:SAVERM_RS12095
uniprot id: Q81ZI7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PAPS reductase family. CysD subfamily.
messages: Heterodimer composed of CysD, the smaller subunit, and CysN.
messages: With CysN forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.

227882:SAVERM RS33060
gene id: 227882:SAVERM_RS33060
uniprot id: Q829I1
names: Similarity
messages: Belongs to the asp23 family.

227882:SAVERM RS27590
gene id: 227882:SAVERM_RS27590
uniprot id: Q82CK0
names: Subcellular Location Annotation
messages: Membrane

227882:SAVERM RS34325
gene id: 227882:SAVERM_RS34325
uniprot id: Q828I8
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
messages: Cytoplasm
messages: The 20S proteasome core is composed of 14 alpha and 14 beta subunits that assemble into four stacked heptameric rings, resulting in a barrel-shaped structure. The two inner rings, each composed of seven catalytic beta subunits, are sandwiched by two outer rings, each composed of seven alpha subunits. The catalytic chamber with the active sites is on the inside of the barrel. Has a gated structure, the ends of the cylinder being occluded by the N-termini of the alpha-subunits. Is capped by the proteasome-associated ATPase, ARC.
messages: The formation of the proteasomal ATPase ARC-20S proteasome complex, likely via the docking of the C-termini of ARC into the intersubunit pockets in the alpha-rings, may trigger opening of the gate for substrate entry. Interconversion between the open-gate and close-gate conformations leads to a dynamic regulation of the 20S proteasome proteolysis activity.

227882:SAVERM RS08495
gene id: 227882:SAVERM_RS08495
uniprot id: Q82MQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

227882:SAVERM RS31040
gene id: 227882:SAVERM_RS31040
uniprot id: Q82AN3
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

227882:SAVERM RS23830
gene id: 227882:SAVERM_RS23830
uniprot id: Q82EJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-insensitive subfamily.
messages: Cell membrane
messages: Homodimer.
messages: Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force.

227882:SAVERM RS07780
gene id: 227882:SAVERM_RS07780
uniprot id: Q82N40
names: Subcellular Location Annotation
messages: Membrane

227882:SAVERM RS35575
gene id: 227882:SAVERM_RS35575
uniprot id: Q827J9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase-binding protein RbpA family.
messages: Bind 1 Zn(2+) per subunit.
messages: Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters.
messages: Forms a complex with the RNAP catalytic core and with free principal sigma factors.

227882:SAVERM RS01365
gene id: 227882:SAVERM_RS01365
uniprot id: Q82RF7
names: Subcellular Location Annotation
messages: Membrane

227882:SAVERM RS24875
gene id: 227882:SAVERM_RS24875
uniprot id: Q82DZ6
names: Subcellular Location Annotation
messages: Cytoplasm

227882:SAVERM RS24340
gene id: 227882:SAVERM_RS24340
uniprot id: Q82E99
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.

227882:SAVERM RS08595
gene id: 227882:SAVERM_RS08595
uniprot id: Q82MN8
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

227882:SAVERM RS29855
gene id: 227882:SAVERM_RS29855
uniprot id: Q82BB5
names: Similarity
messages: Belongs to the pirin family.

227882:SAVERM RS03395
gene id: 227882:SAVERM_RS03395
uniprot id: Q82QD0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SsgA family.
messages: Cell septum

227882:SAVERM RS21880
gene id: 227882:SAVERM_RS21880
uniprot id: Q82FM1
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

227882:SAVERM RS08850
gene id: 227882:SAVERM_RS08850
uniprot id: Q82MI8
names: Similarity
messages: Belongs to the DAMOX/DASOX family.

227882:SAVERM RS14455
gene id: 227882:SAVERM_RS14455
uniprot id: Q82JH8
names: Similarity
messages: Belongs to the glycosyl hydrolase 25 family.

227882:SAVERM RS07180
gene id: 227882:SAVERM_RS07180
uniprot id: Q82NG1
names: Subcellular Location Annotation
messages: Membrane

227882:SAVERM RS09600
gene id: 227882:SAVERM_RS09600
uniprot id: Q82M41
names: Similarity
messages: Belongs to the TPP enzyme family.

227882:SAVERM RS32365
gene id: 227882:SAVERM_RS32365
uniprot id: Q829W8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

227882:SAVERM RS36105
gene id: 227882:SAVERM_RS36105
uniprot id: Q826Z8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Membrane

227882:SAVERM RS13820
gene id: 227882:SAVERM_RS13820
uniprot id: Q82JU9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

227882:SAVERM RS28120
gene id: 227882:SAVERM_RS28120
uniprot id: Q82CA7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

227882:SAVERM RS41630
gene id: 227882:SAVERM_RS41630
uniprot id: Q82J65
names: Function
names: Similarity
messages: Belongs to the threonine synthase family.
messages: Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.

227882:SAVERM RS10335
gene id: 227882:SAVERM_RS10335
uniprot id: Q82LP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

227882:SAVERM RS32685
gene id: 227882:SAVERM_RS32685
uniprot id: Q829Q4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

227882:SAVERM RS27785
gene id: 227882:SAVERM_RS27785
uniprot id: Q82CG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

227882:SAVERM RS18430
gene id: 227882:SAVERM_RS18430
uniprot id: Q82HE2
names: Subcellular Location Annotation
messages: Membrane

227882:SAVERM RS35155
gene id: 227882:SAVERM_RS35155
uniprot id: Q827T4
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

227882:SAVERM RS29840
gene id: 227882:SAVERM_RS29840
uniprot id: Q82BB8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

227882:SAVERM RS21745
gene id: 227882:SAVERM_RS21745
uniprot id: Q82FP8
names: Similarity
messages: Belongs to the protease inhibitor I16 (SSI) family.

227882:SAVERM RS34155
gene id: 227882:SAVERM_RS34155
uniprot id: Q828M2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MshC subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent condensation of GlcN-Ins and L-cysteine to form L-Cys-GlcN-Ins.
messages: Monomer.

227882:SAVERM RS11215
gene id: 227882:SAVERM_RS11215
uniprot id: Q82L76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

227882:SAVERM RS41635
gene id: 227882:SAVERM_RS41635
uniprot id: Q82J64
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

227882:SAVERM RS37960
gene id: 227882:SAVERM_RS37960
uniprot id: Q825R2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgE subfamily.
messages: Homodimer.
messages: Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1->4)-glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB.

227882:SAVERM RS13080
gene id: 227882:SAVERM_RS13080
uniprot id: Q82K93
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Cell membrane
messages: Consists of an N-terminal domain, which is sufficient for the localization to the septal ring and is required for cell division, followed by a linker domain, and a C-terminal domain, which forms the translocation motor involved in chromosome segregation. The C-terminal domain can be further subdivided into alpha, beta and gamma subdomains. The alpha and beta subdomains form the DNA pump, and the gamma subdomain is a regulatory subdomain (By similarity).
messages: Essential cell division protein that coordinates cell division and chromosome segregation. The N-terminus is involved in assembly of the cell-division machinery. The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the dif recombination site, which is located within the replication terminus region. Required for activation of the Xer recombinase, allowing activation of chromosome unlinking by recombination (By similarity).
messages: Homohexamer. Forms a ring that surrounds DNA (By similarity).

227882:SAVERM RS31280
gene id: 227882:SAVERM_RS31280
uniprot id: Q82AI5
names: Similarity
messages: Belongs to the arsA ATPase family.

227882:SAVERM RS04075
gene id: 227882:SAVERM_RS04075
uniprot id: Q82Q04
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

227882:SAVERM RS27445
gene id: 227882:SAVERM_RS27445
uniprot id: Q82CM8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbsD / FucU family. RbsD subfamily.
messages: Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose.
messages: Cytoplasm
messages: Homodecamer.

227882:SAVERM RS10330
gene id: 227882:SAVERM_RS10330
uniprot id: Q82LQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

227882:SAVERM RS33215
gene id: 227882:SAVERM_RS33215
uniprot id: Q829F0
names: Similarity
messages: Belongs to the peptidase U62 family.

227882:SAVERM RS24030
gene id: 227882:SAVERM_RS24030
uniprot id: Q82EG1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

227882:SAVERM RS35075
gene id: 227882:SAVERM_RS35075
uniprot id: Q827U5
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.

227882:SAVERM RS12565
gene id: 227882:SAVERM_RS12565
uniprot id: Q82KJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Cytoplasm
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the insertion of ferrous iron into coproporphyrin III to form Fe-coproporphyrin III.

227882:SAVERM RS35795
gene id: 227882:SAVERM_RS35795
uniprot id: Q827F5
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

227882:SAVERM RS23820
gene id: 227882:SAVERM_RS23820
uniprot id: Q82EK0
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

227882:SAVERM RS26635
gene id: 227882:SAVERM_RS26635
uniprot id: Q82D26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family.
messages: Membrane

227882:SAVERM RS02575
gene id: 227882:SAVERM_RS02575
uniprot id: Q79ZT4
names: Similarity
messages: Belongs to the cytochrome P450 family.

227882:SAVERM RS15615
gene id: 227882:SAVERM_RS15615
uniprot id: Q82IX6
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

227882:SAVERM RS12090
gene id: 227882:SAVERM_RS12090
uniprot id: Q82KR0
names: Caution
names: Function
names: Similarity
messages: Belongs to the APS kinase family.
messages: Catalyzes the synthesis of activated sulfate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

227882:SAVERM RS30030
gene id: 227882:SAVERM_RS30030
uniprot id: Q82B81
names: Subcellular Location Annotation
messages: Membrane

227882:SAVERM RS16630
gene id: 227882:SAVERM_RS16630
uniprot id: Q82IE7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

227882:SAVERM RS36890
gene id: 227882:SAVERM_RS36890
uniprot id: Q93HF3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the xylose isomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.

227882:SAVERM RS20065
gene id: 227882:SAVERM_RS20065
uniprot id: Q82GL0
names: Subcellular Location Annotation
messages: Membrane

227882:SAVERM RS15545
gene id: 227882:SAVERM_RS15545
uniprot id: Q82IZ1
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the PhyH family.
messages: Catalyzes the conversion of 1-deoxypentalenic acid to 11-beta-hydroxy-1-deoxypentalenic acid in the biosynthesis of neopentalenolactone antibiotic.
messages: S.avermitilis does not produce pentalenolactone itself in vivo but instead a group of new metabolites that are neopentalenolactone derivatives.

227882:SAVERM RS35150
gene id: 227882:SAVERM_RS35150
uniprot id: Q827T5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

227882:SAVERM RS25760
gene id: 227882:SAVERM_RS25760
uniprot id: Q82DI3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

227882:SAVERM RS13785
gene id: 227882:SAVERM_RS13785
uniprot id: Q82JV6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

227882:SAVERM RS15675
gene id: 227882:SAVERM_RS15675
uniprot id: P59689
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
messages: Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.

227882:SAVERM RS36075
gene id: 227882:SAVERM_RS36075
uniprot id: Q827A4
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane

227882:SAVERM RS02235
gene id: 227882:SAVERM_RS02235
uniprot id: Q82QZ7
names: Function
names: Similarity
messages: Belongs to the catalase family. HPII subfamily.
messages: Serves to protect cells from the toxic effects of hydrogen peroxide.

227882:SAVERM RS37220
gene id: 227882:SAVERM_RS37220
uniprot id: Q826E8
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

227882:SAVERM RS16760
gene id: 227882:SAVERM_RS16760
uniprot id: Q82IC1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

227882:SAVERM RS05635
gene id: 227882:SAVERM_RS05635
uniprot id: Q82PA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

227882:SAVERM RS22130
gene id: 227882:SAVERM_RS22130
uniprot id: Q82FH2
names: Subcellular Location Annotation
messages: Membrane

227882:SAVERM RS09450
gene id: 227882:SAVERM_RS09450
uniprot id: Q82M69
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the GTP cyclohydrolase II family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.

227882:SAVERM RS28005
gene id: 227882:SAVERM_RS28005
uniprot id: Q82CC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family.
messages: Membrane

227882:SAVERM RS29170
gene id: 227882:SAVERM_RS29170
uniprot id: Q82BQ0
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.

227882:SAVERM RS11355
gene id: 227882:SAVERM_RS11355
uniprot id: Q82L49
names: Similarity
messages: Belongs to the terpene synthase family.

227882:SAVERM RS20770
gene id: 227882:SAVERM_RS20770
uniprot id: Q82G68
names: Caution
names: Similarity
messages: Belongs to the nitrobindin family.
messages: Lacks the conserved His residue that binds heme iron in the nitrobindin family.

227882:SAVERM RS11455
gene id: 227882:SAVERM_RS11455
uniprot id: Q82L29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

227882:SAVERM RS32590
gene id: 227882:SAVERM_RS32590
uniprot id: Q829S2
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

227882:SAVERM RS22255
gene id: 227882:SAVERM_RS22255
uniprot id: Q82FE8
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

227882:SAVERM RS09960
gene id: 227882:SAVERM_RS09960
uniprot id: Q82LX1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gas vesicle protein type A family.
messages: Gas vesicles are small, hollow, gas filled protein structures that are found in several microbial planktonic microorganisms. They allow the positioning of the organism at the favorable depth for growth. GvpA type proteins form the essential core of the structure.
messages: gas vesicle membrane

227882:SAVERM RS20740
gene id: 227882:SAVERM_RS20740
uniprot id: Q82G74
names: Similarity
names: Subunit
messages: Belongs to the acetyltransferase Eis family.
messages: Homohexamer; trimer of dimers.

227882:SAVERM RS35270
gene id: 227882:SAVERM_RS35270
uniprot id: Q827R2
names: Function
names: Similarity
messages: Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
messages: Regulates the transcription of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines.

227882:SAVERM RS07365
gene id: 227882:SAVERM_RS07365
uniprot id: Q82NC2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

227882:SAVERM RS21945
gene id: 227882:SAVERM_RS21945
uniprot id: Q82FK8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.

227882:SAVERM RS13680
gene id: 227882:SAVERM_RS13680
uniprot id: Q82JX7
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

227882:SAVERM RS35120
gene id: 227882:SAVERM_RS35120
uniprot id: Q820F5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RuvC family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.

227882:SAVERM RS17810
gene id: 227882:SAVERM_RS17810
uniprot id: Q82HR5
names: Subcellular Location Annotation
messages: Membrane

227882:SAVERM RS11520
gene id: 227882:SAVERM_RS11520
uniprot id: Q82L16
names: Subcellular Location Annotation
messages: Cell membrane

227882:SAVERM RS20530
gene id: 227882:SAVERM_RS20530
uniprot id: Q82GB8
names: Function
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

227882:SAVERM RS32965
gene id: 227882:SAVERM_RS32965
uniprot id: Q829K0
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

227882:SAVERM RS31570
gene id: 227882:SAVERM_RS31570
uniprot id: Q82AC9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

227882:SAVERM RS14235
gene id: 227882:SAVERM_RS14235
uniprot id: Q82JM3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

227882:SAVERM RS25250
gene id: 227882:SAVERM_RS25250
uniprot id: Q82DS4
names: Subcellular Location Annotation
messages: Membrane

227882:SAVERM RS17110
gene id: 227882:SAVERM_RS17110
uniprot id: Q82I53
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

227882:SAVERM RS31250
gene id: 227882:SAVERM_RS31250
uniprot id: Q82AJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 87 family.
messages: Membrane

227882:SAVERM RS24620
gene id: 227882:SAVERM_RS24620
uniprot id: Q82E48
names: Subcellular Location Annotation
messages: Cell membrane

227882:SAVERM RS26620
gene id: 227882:SAVERM_RS26620
uniprot id: Q82D29
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

227882:SAVERM RS26420
gene id: 227882:SAVERM_RS26420
uniprot id: Q82D63
names: Subcellular Location Annotation
messages: Membrane

227882:SAVERM RS06355
gene id: 227882:SAVERM_RS06355
uniprot id: Q82NW7
names: Subcellular Location Annotation
messages: Membrane

227882:SAVERM RS14230
gene id: 227882:SAVERM_RS14230
uniprot id: Q59818
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.

227882:SAVERM RS07690
gene id: 227882:SAVERM_RS07690
uniprot id: Q82N58
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

227882:SAVERM RS30025
gene id: 227882:SAVERM_RS30025
uniprot id: Q82B82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

227882:SAVERM RS25100
gene id: 227882:SAVERM_RS25100
uniprot id: Q82DV4
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

227882:SAVERM RS23160
gene id: 227882:SAVERM_RS23160
uniprot id: Q82EX9
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock (By similarity).

227882:SAVERM RS35130
gene id: 227882:SAVERM_RS35130
uniprot id: Q820F3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvB family.
messages: Forms a complex with RuvA.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.

227882:SAVERM RS08875
gene id: 227882:SAVERM_RS08875
uniprot id: Q82MI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family.
messages: Membrane

227882:SAVERM RS35865
gene id: 227882:SAVERM_RS35865
uniprot id: Q827E5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sbp family.
messages: Cell membrane

227882:SAVERM RS31525
gene id: 227882:SAVERM_RS31525
uniprot id: Q82AD7
names: Subcellular Location Annotation
messages: Membrane

227882:SAVERM RS14805
gene id: 227882:SAVERM_RS14805
uniprot id: Q82JB7
names: Similarity
messages: Belongs to the UPF0045 family.

227882:SAVERM RS01105
gene id: 227882:SAVERM_RS01105
uniprot id: Q82RK5
names: Subcellular Location Annotation
messages: Membrane

227882:SAVERM RS29045
gene id: 227882:SAVERM_RS29045
uniprot id: Q82BS5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

227882:SAVERM RS15575
gene id: 227882:SAVERM_RS15575
uniprot id: Q82IY4
names: Cofactor
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the terpene synthase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Catalyzes the cyclization of farnesyl diphosphate (FPP) to the tricyclic sesquiterpene pentalenene in the biosynthesis of neopentalenolactone antibiotic.
messages: Monomer.
messages: S.avermitilis does not produce pentalenolactone itself in vivo but instead a group of new metabolites that are neopentalenolactone derivatives.
messages: The Asp-Asp-Xaa-Xaa-Asp/Glu (DDXXD/E) motif is important for the catalytic activity, presumably through binding to Mg(2+).

227882:SAVERM RS17085
gene id: 227882:SAVERM_RS17085
uniprot id: Q82I57
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

227882:SAVERM RS14685
gene id: 227882:SAVERM_RS14685
uniprot id: Q82JD2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the CobB/CobQ family.
messages: Involved in acetate metabolism.
messages: The N-terminal region seems to be important for proper quaternary structure. The C-terminal region contains the substrate-binding site (By similarity).

227882:SAVERM RS35235
gene id: 227882:SAVERM_RS35235
uniprot id: Q827R8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm

227882:SAVERM RS29380
gene id: 227882:SAVERM_RS29380
uniprot id: Q82BL0
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

227882:SAVERM RS32950
gene id: 227882:SAVERM_RS32950
uniprot id: Q829K3
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

227882:SAVERM RS37855
gene id: 227882:SAVERM_RS37855
uniprot id: Q825T4
names: Similarity
messages: Belongs to the peptidase A31 family.

227882:SAVERM RS17985
gene id: 227882:SAVERM_RS17985
uniprot id: Q82HM8
names: Subcellular Location Annotation
messages: Cell membrane

227882:SAVERM RS26125
gene id: 227882:SAVERM_RS26125
uniprot id: Q82DB8
names: Subcellular Location Annotation
messages: Cell membrane

227882:SAVERM RS36380
gene id: 227882:SAVERM_RS36380
uniprot id: Q826U4
names: Subcellular Location Annotation
messages: Membrane

227882:SAVERM RS34065
gene id: 227882:SAVERM_RS34065
uniprot id: Q79Z35
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

227882:SAVERM RS31995
gene id: 227882:SAVERM_RS31995
uniprot id: Q82A42
names: Similarity
names: Subunit
messages: Belongs to the pyruvate kinase family.
messages: Homotetramer.

227882:SAVERM RS18470
gene id: 227882:SAVERM_RS18470
uniprot id: Q82HD4
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

227882:SAVERM RS08770
gene id: 227882:SAVERM_RS08770
uniprot id: Q82MK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

227882:SAVERM RS22030
gene id: 227882:SAVERM_RS22030
uniprot id: Q82FJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell inner membrane
messages: Membrane

227882:SAVERM RS07085
gene id: 227882:SAVERM_RS07085
uniprot id: Q82NH9
names: Similarity
messages: Belongs to the glycosyl hydrolase 53 family.

227882:SAVERM RS24775
gene id: 227882:SAVERM_RS24775
uniprot id: Q82E16
names: Subcellular Location Annotation
messages: Membrane

227882:SAVERM RS22260
gene id: 227882:SAVERM_RS22260
uniprot id: Q82FE7
names: Similarity
messages: Belongs to the thioredoxin family.

227882:SAVERM RS13700
gene id: 227882:SAVERM_RS13700
uniprot id: Q82JX3
names: Similarity
messages: Belongs to the DprA/Smf family.

227882:SAVERM RS08335
gene id: 227882:SAVERM_RS08335
uniprot id: Q82MT8
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
messages: Part of the 50S ribosomal subunit.

227882:SAVERM RS20905
gene id: 227882:SAVERM_RS20905
uniprot id: Q82G41
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

227882:SAVERM RS14165
gene id: 227882:SAVERM_RS14165
uniprot id: Q82JN7
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

227882:SAVERM RS34885
gene id: 227882:SAVERM_RS34885
uniprot id: Q827X5
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

227882:SAVERM RS36315
gene id: 227882:SAVERM_RS36315
uniprot id: Q826V7
names: Similarity
names: Subunit
messages: Belongs to the sigma-70 factor family. ECF subfamily.
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

227882:SAVERM RS27105
gene id: 227882:SAVERM_RS27105
uniprot id: Q82CT7
names: Subcellular Location Annotation
messages: Cell membrane

227882:SAVERM RS26285
gene id: 227882:SAVERM_RS26285
uniprot id: Q82D86
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

227882:SAVERM RS10145
gene id: 227882:SAVERM_RS10145
uniprot id: Q82LT5
names: Similarity
messages: Belongs to the gluconokinase GntK/GntV family.

227882:SAVERM RS25000
gene id: 227882:SAVERM_RS25000
uniprot id: Q82DX3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

227882:SAVERM RS20035
gene id: 227882:SAVERM_RS20035
uniprot id: Q82GL6
names: Similarity
messages: Belongs to the cytochrome P450 family.

227882:SAVERM RS32785
gene id: 227882:SAVERM_RS32785
uniprot id: Q829N5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polysaccharide lyase 1 family.
messages: Secreted

227882:SAVERM RS10860
gene id: 227882:SAVERM_RS10860
uniprot id: Q82LE4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Membrane

227882:SAVERM RS23315
gene id: 227882:SAVERM_RS23315
uniprot id: Q82EU9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent (By similarity).
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK (By similarity).
messages: The Clp repeat (R) domain probably functions as a substrate-discriminating domain, recruiting aggregated proteins to the ClpB hexamer and/or stabilizing bound proteins. The NBD2 domain is responsible for oligomerization, whereas the NBD1 domain stabilizes the hexamer probably in an ATP-dependent manner. The movement of the coiled-coil domain is essential for ClpB ability to rescue proteins from an aggregated state, probably by pulling apart large aggregated proteins, which are bound between the coiled-coils motifs of adjacent ClpB subunits in the functional hexamer (By similarity).

227882:SAVERM RS19940
gene id: 227882:SAVERM_RS19940
uniprot id: Q82GN7
names: Similarity
messages: Belongs to the iron/ascorbate-dependent oxidoreductase family.

227882:SAVERM RS07430
gene id: 227882:SAVERM_RS07430
uniprot id: Q82NB0
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

227882:SAVERM RS30235
gene id: 227882:SAVERM_RS30235
uniprot id: Q82B40
names: Subcellular Location Annotation
messages: Membrane

227882:SAVERM RS18260
gene id: 227882:SAVERM_RS18260
uniprot id: Q82HH4
names: Similarity
messages: Belongs to the transglycosylase family. Rpf subfamily.

227882:SAVERM RS35680
gene id: 227882:SAVERM_RS35680
uniprot id: Q827H8
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

227882:SAVERM RS05260
gene id: 227882:SAVERM_RS05260
uniprot id: Q820G8
names: Similarity
messages: Belongs to the glutamate synthase family.

227882:SAVERM RS36625
gene id: 227882:SAVERM_RS36625
uniprot id: Q79Z25
names: Similarity
messages: Belongs to the cytochrome P450 family.

227882:SAVERM RS24970
gene id: 227882:SAVERM_RS24970
uniprot id: Q82DX9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 30 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

227882:SAVERM RS25570
gene id: 227882:SAVERM_RS25570
uniprot id: Q82DM1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.

227882:SAVERM RS34045
gene id: 227882:SAVERM_RS34045
uniprot id: Q828N6
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

227882:SAVERM RS19030
gene id: 227882:SAVERM_RS19030
uniprot id: Q82H58
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

227882:SAVERM RS18550
gene id: 227882:SAVERM_RS18550
uniprot id: Q82HB9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Belongs to the precorrin methyltransferase family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

227882:SAVERM RS13065
gene id: 227882:SAVERM_RS13065
uniprot id: Q82K96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

227882:SAVERM RS08990
gene id: 227882:SAVERM_RS08990
uniprot id: Q82MG0
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit A family.

227882:SAVERM RS17730
gene id: 227882:SAVERM_RS17730
uniprot id: Q82HT1
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

227882:SAVERM RS23060
gene id: 227882:SAVERM_RS23060
uniprot id: Q82EZ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate.
messages: Homotrimer.

227882:SAVERM RS09765
gene id: 227882:SAVERM_RS09765
uniprot id: Q82M09
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

227882:SAVERM RS07100
gene id: 227882:SAVERM_RS07100
uniprot id: Q82NH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

227882:SAVERM RS29080
gene id: 227882:SAVERM_RS29080
uniprot id: Q82BR8
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family.

227882:SAVERM RS17945
gene id: 227882:SAVERM_RS17945
uniprot id: Q82HN6
names: Subcellular Location Annotation
messages: Membrane

227882:SAVERM RS28765
gene id: 227882:SAVERM_RS28765
uniprot id: Q82BY0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S41B family.
messages: Cytoplasm
messages: Degrades oligopeptides.

227882:SAVERM RS11655
gene id: 227882:SAVERM_RS11655
uniprot id: Q82KZ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protoporphyrinogen/coproporphyrinogen oxidase family. Coproporphyrinogen III oxidase subfamily.
messages: Cytoplasm
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the oxidation of coproporphyrinogen III to coproporphyrin III.

227882:SAVERM RS34070
gene id: 227882:SAVERM_RS34070
uniprot id: Q93H19
names: Similarity
messages: Belongs to the UPF0225 family.

227882:SAVERM RS37865
gene id: 227882:SAVERM_RS37865
uniprot id: Q825T3
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. HypB/HupM subfamily.

227882:SAVERM RS27010
gene id: 227882:SAVERM_RS27010
uniprot id: Q82CV5
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

227882:SAVERM RS20480
gene id: 227882:SAVERM_RS20480
uniprot id: Q82GC9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).

227882:SAVERM RS33545
gene id: 227882:SAVERM_RS33545
uniprot id: Q828Y7
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

227882:SAVERM RS10400
gene id: 227882:SAVERM_RS10400
uniprot id: Q82LN6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

227882:SAVERM RS35905
gene id: 227882:SAVERM_RS35905
uniprot id: Q827D7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

227882:SAVERM RS31890
gene id: 227882:SAVERM_RS31890
uniprot id: Q82A63
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

227882:SAVERM RS26565
gene id: 227882:SAVERM_RS26565
uniprot id: Q82D37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

227882:SAVERM RS05135
gene id: 227882:SAVERM_RS05135
uniprot id: Q82PH2
names: Similarity
messages: Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family.

227882:SAVERM RS31550
gene id: 227882:SAVERM_RS31550
uniprot id: Q82AD3
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

227882:SAVERM RS35655
gene id: 227882:SAVERM_RS35655
uniprot id: Q827I3
names: Subcellular Location Annotation
messages: Membrane

227882:SAVERM RS12570
gene id: 227882:SAVERM_RS12570
uniprot id: Q82KJ5
names: Subcellular Location Annotation
messages: Membrane

227882:SAVERM RS31545
gene id: 227882:SAVERM_RS31545
uniprot id: Q82AD4
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

227882:SAVERM RS21380
gene id: 227882:SAVERM_RS21380
uniprot id: Q82FW2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

227882:SAVERM RS20160
gene id: 227882:SAVERM_RS20160
uniprot id: Q82GJ1
names: Function
names: Similarity
messages: Belongs to the MqnA/MqnD family. MqnD subfamily.
messages: Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2).

227882:SAVERM RS28130
gene id: 227882:SAVERM_RS28130
uniprot id: Q82CA5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

227882:SAVERM RS20910
gene id: 227882:SAVERM_RS20910
uniprot id: Q82G40
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetyltransferase family. MshD subfamily.
messages: Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol.
messages: Monomer.

227882:SAVERM RS09345
gene id: 227882:SAVERM_RS09345
uniprot id: Q82M90
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

227882:SAVERM RS35685
gene id: 227882:SAVERM_RS35685
uniprot id: Q827H7
names: Subcellular Location Annotation
messages: Membrane

227882:SAVERM RS18705
gene id: 227882:SAVERM_RS18705
uniprot id: Q82H87
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

227882:SAVERM RS15640
gene id: 227882:SAVERM_RS15640
uniprot id: Q82IX2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

227882:SAVERM RS16190
gene id: 227882:SAVERM_RS16190
uniprot id: Q82IL0
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

227882:SAVERM RS12030
gene id: 227882:SAVERM_RS12030
uniprot id: Q82KS1
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

227882:SAVERM RS37260
gene id: 227882:SAVERM_RS37260
uniprot id: Q826D9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
messages: Homotetramer.
messages: Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.

227882:SAVERM RS12120
gene id: 227882:SAVERM_RS12120
uniprot id: Q82KQ5
names: Subcellular Location Annotation
messages: Membrane

227882:SAVERM RS37060
gene id: 227882:SAVERM_RS37060
uniprot id: Q826H9
names: Cofactor
names: Similarity
messages: Belongs to the monomeric-type IDH family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

227882:SAVERM RS22825
gene id: 227882:SAVERM_RS22825
uniprot id: Q82F46
names: Subcellular Location Annotation
messages: Cell membrane

227882:SAVERM RS22330
gene id: 227882:SAVERM_RS22330
uniprot id: Q82FD4
names: Similarity
messages: Belongs to the UPF0232 family.

227882:SAVERM RS18415
gene id: 227882:SAVERM_RS18415
uniprot id: Q82HE5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

227882:SAVERM RS18765
gene id: 227882:SAVERM_RS18765
uniprot id: Q79Z83
names: Subcellular Location Annotation
messages: Membrane

227882:SAVERM RS24975
gene id: 227882:SAVERM_RS24975
uniprot id: Q82DX8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

227882:SAVERM RS09005
gene id: 227882:SAVERM_RS09005
uniprot id: Q82MF7
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

227882:SAVERM RS05625
gene id: 227882:SAVERM_RS05625
uniprot id: Q79ZK6
names: Similarity
messages: Belongs to the glycosyl hydrolase 42 family.

227882:SAVERM RS34225
gene id: 227882:SAVERM_RS34225
uniprot id: Q828K8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acireductone dioxygenase (ARD) family.
messages: Binds 1 Fe(2+) cation per monomer.
messages: Binds 1 nickel ion per monomer.
messages: Catalyzes 2 different reactions between oxygen and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
messages: Monomer.

227882:SAVERM RS29620
gene id: 227882:SAVERM_RS29620
uniprot id: Q82BG2
names: Similarity
messages: Belongs to the glycosyl hydrolase 51 family.

227882:SAVERM RS18555
gene id: 227882:SAVERM_RS18555
uniprot id: Q82HB8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 39 family.
messages: Cell membrane
messages: Membrane
messages: Transfers mannose from Dol-P-mannose to Ser or Thr residues on proteins.

227882:SAVERM RS02230
gene id: 227882:SAVERM_RS02230
uniprot id: Q82QZ8
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

227882:SAVERM RS25200
gene id: 227882:SAVERM_RS25200
uniprot id: Q82DT4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

227882:SAVERM RS23155
gene id: 227882:SAVERM_RS23155
uniprot id: Q82EY0
names: Subcellular Location Annotation
messages: Membrane

227882:SAVERM RS09930
gene id: 227882:SAVERM_RS09930
uniprot id: Q82LX7
names: Function
names: Subcellular Location Annotation
messages: May play a structural or regulatory role in gas vesicle synthesis.
messages: Vesicle
messages: gas vesicle

227882:SAVERM RS16505
gene id: 227882:SAVERM_RS16505
uniprot id: Q82IG0
names: Similarity
messages: Belongs to the Nudix hydrolase family.

227882:SAVERM RS33325
gene id: 227882:SAVERM_RS33325
uniprot id: Q829C7
names: Similarity
messages: Belongs to the UPF0098 family.

227882:SAVERM RS08910
gene id: 227882:SAVERM_RS08910
uniprot id: Q82MH6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endonuclease V family.
messages: Cytoplasm
messages: DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA.

227882:SAVERM RS13945
gene id: 227882:SAVERM_RS13945
uniprot id: Q82JS5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

227882:SAVERM RS34580
gene id: 227882:SAVERM_RS34580
uniprot id: Q828D6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S8 family.
messages: Cell membrane
messages: Membrane

227882:SAVERM RS27180
gene id: 227882:SAVERM_RS27180
uniprot id: Q82CS3
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

227882:SAVERM RS25370
gene id: 227882:SAVERM_RS25370
uniprot id: Q82DQ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

227882:SAVERM RS15785
gene id: 227882:SAVERM_RS15785
uniprot id: Q82IU3
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

227882:SAVERM RS35255
gene id: 227882:SAVERM_RS35255
uniprot id: Q827R4
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

227882:SAVERM RS27070
gene id: 227882:SAVERM_RS27070
uniprot id: Q82CU4
names: Subcellular Location Annotation
messages: Membrane

227882:SAVERM RS02365
gene id: 227882:SAVERM_RS02365
uniprot id: Q82QX2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

227882:SAVERM RS13960
gene id: 227882:SAVERM_RS13960
uniprot id: Q82JS2
names: Function
names: Similarity
messages: Belongs to the CofC family.
messages: Guanylyltransferase that catalyzes the activation of phosphoenolpyruvate (PEP) as enolpyruvoyl-2-diphospho-5'-guanosine, via the condensation of PEP with GTP. It is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor.

227882:SAVERM RS34740
gene id: 227882:SAVERM_RS34740
uniprot id: Q828A4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

227882:SAVERM RS31530
gene id: 227882:SAVERM_RS31530
uniprot id: Q820F6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).

227882:SAVERM RS09485
gene id: 227882:SAVERM_RS09485
uniprot id: Q82M62
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

227882:SAVERM RS25350
gene id: 227882:SAVERM_RS25350
uniprot id: Q82DQ9
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

227882:SAVERM RS03005
gene id: 227882:SAVERM_RS03005
uniprot id: Q82QK2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

227882:SAVERM RS08620
gene id: 227882:SAVERM_RS08620
uniprot id: Q82MN4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

227882:SAVERM RS03205
gene id: 227882:SAVERM_RS03205
uniprot id: Q82QG3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

227882:SAVERM RS09490
gene id: 227882:SAVERM_RS09490
uniprot id: Q82M61
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

227882:SAVERM RS10430
gene id: 227882:SAVERM_RS10430
uniprot id: Q82LN0
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

227882:SAVERM RS20765
gene id: 227882:SAVERM_RS20765
uniprot id: Q82G69
names: Similarity
messages: Belongs to the Fur family.

227882:SAVERM RS36865
gene id: 227882:SAVERM_RS36865
uniprot id: Q826L1
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

227882:SAVERM RS17160
gene id: 227882:SAVERM_RS17160
uniprot id: Q82I44
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

227882:SAVERM RS13930
gene id: 227882:SAVERM_RS13930
uniprot id: Q82JS8
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

227882:SAVERM RS21775
gene id: 227882:SAVERM_RS21775
uniprot id: Q82FP2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

227882:SAVERM RS14995
gene id: 227882:SAVERM_RS14995
uniprot id: Q82J79
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

227882:SAVERM RS18475
gene id: 227882:SAVERM_RS18475
uniprot id: Q82HD3
names: Cofactor
names: Similarity
messages: Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.
messages: Binds 1 zinc ion per subunit.

227882:SAVERM RS12895
gene id: 227882:SAVERM_RS12895
uniprot id: Q82KD0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

227882:SAVERM RS05155
gene id: 227882:SAVERM_RS05155
uniprot id: Q82PG8
names: Subcellular Location Annotation
messages: Membrane

227882:SAVERM RS11460
gene id: 227882:SAVERM_RS11460
uniprot id: Q82L28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

227882:SAVERM RS03825
gene id: 227882:SAVERM_RS03825
uniprot id: Q82Q58
names: Similarity
names: Subunit
messages: Belongs to the sigma-70 factor family. ECF subfamily.
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

227882:SAVERM RS30815
gene id: 227882:SAVERM_RS30815
uniprot id: Q82AS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

227882:SAVERM RS35755
gene id: 227882:SAVERM_RS35755
uniprot id: Q827G3
names: Similarity
messages: Belongs to the oxoprolinase family.

227882:SAVERM RS32555
gene id: 227882:SAVERM_RS32555
uniprot id: Q829T0
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.

227882:SAVERM RS11780
gene id: 227882:SAVERM_RS11780
uniprot id: Q82KW4
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

227882:SAVERM RS21260
gene id: 227882:SAVERM_RS21260
uniprot id: Q82FY1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the GTP cyclohydrolase II family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.

227882:SAVERM RS27255
gene id: 227882:SAVERM_RS27255
uniprot id: Q82CR3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

227882:SAVERM RS07715
gene id: 227882:SAVERM_RS07715
uniprot id: Q82N53
names: Similarity
messages: Belongs to the glycosyl hydrolase 67 family.

227882:SAVERM RS36560
gene id: 227882:SAVERM_RS36560
uniprot id: Q826Q8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

227882:SAVERM RS01845
gene id: 227882:SAVERM_RS01845
uniprot id: Q82R68
names: Similarity
messages: Belongs to the Nudix hydrolase family.

227882:SAVERM RS13760
gene id: 227882:SAVERM_RS13760
uniprot id: Q82JW1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: A probable RNA-binding protein.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm

227882:SAVERM RS14300
gene id: 227882:SAVERM_RS14300
uniprot id: Q82JL0
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

227882:SAVERM RS26480
gene id: 227882:SAVERM_RS26480
uniprot id: Q82D51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

227882:SAVERM RS17120
gene id: 227882:SAVERM_RS17120
uniprot id: Q82I51
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

227882:SAVERM RS24560
gene id: 227882:SAVERM_RS24560
uniprot id: Q82E60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0060 family.
messages: Cell membrane

227882:SAVERM RS32815
gene id: 227882:SAVERM_RS32815
uniprot id: Q81ZV8
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

227882:SAVERM RS23280
gene id: 227882:SAVERM_RS23280
uniprot id: Q82EV6
names: Similarity
messages: Belongs to the peptidase C40 family.

227882:SAVERM RS14585
gene id: 227882:SAVERM_RS14585
uniprot id: Q82JF2
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family. TreS subfamily.

227882:SAVERM RS14170
gene id: 227882:SAVERM_RS14170
uniprot id: Q82JN6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 2 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

227882:SAVERM RS09330
gene id: 227882:SAVERM_RS09330
uniprot id: Q82M93
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 2 subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

227882:SAVERM RS10750
gene id: 227882:SAVERM_RS10750
uniprot id: Q82LG6
names: Similarity
messages: Belongs to the malate synthase family.

227882:SAVERM RS10745
gene id: 227882:SAVERM_RS10745
uniprot id: Q82LG7
names: Cofactor
messages: Can also use Mn(2+) ion.

227882:SAVERM RS22175
gene id: 227882:SAVERM_RS22175
uniprot id: Q82FG4
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

227882:SAVERM RS30485
gene id: 227882:SAVERM_RS30485
uniprot id: Q82AZ3
names: Subcellular Location Annotation
messages: Membrane

227882:SAVERM RS12285
gene id: 227882:SAVERM_RS12285
uniprot id: Q82KM3
names: Function
names: Similarity
messages: Belongs to the gas vesicle protein type A family.
messages: Gas vesicles are small, hollow, gas filled protein structures that are found in several microbial planktonic microorganisms. They allow the positioning of the organism at the favorable depth for growth.

227882:SAVERM RS33255
gene id: 227882:SAVERM_RS33255
uniprot id: Q829E1
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

227882:SAVERM RS33700
gene id: 227882:SAVERM_RS33700
uniprot id: Q828V5
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

227882:SAVERM RS23560
gene id: 227882:SAVERM_RS23560
uniprot id: Q82EQ4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

227882:SAVERM RS16840
gene id: 227882:SAVERM_RS16840
uniprot id: Q82IA5
names: Similarity
messages: Belongs to the GSP E family.

227882:SAVERM RS18335
gene id: 227882:SAVERM_RS18335
uniprot id: Q82HG0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

227882:SAVERM RS35510
gene id: 227882:SAVERM_RS35510
uniprot id: Q827L3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CbxX/CfxQ family.
messages: Cytoplasm

227882:SAVERM RS37135
gene id: 227882:SAVERM_RS37135
uniprot id: Q826G4
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

227882:SAVERM RS27570
gene id: 227882:SAVERM_RS27570
uniprot id: Q82CK4
names: Similarity
messages: Belongs to the TPP enzyme family.

227882:SAVERM RS09775
gene id: 227882:SAVERM_RS09775
uniprot id: Q82M07
names: Similarity
messages: Belongs to the glycosyl hydrolase family 6.

227882:SAVERM RS06170
gene id: 227882:SAVERM_RS06170
uniprot id: Q79ZK2
names: Similarity
messages: Belongs to the melC1 family.

227882:SAVERM RS13360
gene id: 227882:SAVERM_RS13360
uniprot id: Q82K43
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

227882:SAVERM RS34220
gene id: 227882:SAVERM_RS34220
uniprot id: Q828K9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAD-like hydrolase superfamily. MasA/MtnC family.
messages: Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).
messages: Binds 1 Mg(2+) ion per subunit.
messages: Monomer.

227882:SAVERM RS32355
gene id: 227882:SAVERM_RS32355
uniprot id: Q829X0
names: Function
names: Subcellular Location Annotation
messages: Iron-sulfur subunit of the cytochrome bc1 complex, an essential component of the respiratory electron transport chain required for ATP synthesis. The bc1 complex catalyzes the oxidation of menaquinol and the reduction of cytochrome c in the respiratory chain. The bc1 complex operates through a Q-cycle mechanism that couples electron transfer to generation of the proton gradient that drives ATP synthesis.
messages: Membrane

227882:SAVERM RS08800
gene id: 227882:SAVERM_RS08800
uniprot id: Q82MJ8
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.

227882:SAVERM RS13170
gene id: 227882:SAVERM_RS13170
uniprot id: Q82K80
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

227882:SAVERM RS08815
gene id: 227882:SAVERM_RS08815
uniprot id: Q82MJ5
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

227882:SAVERM RS28225
gene id: 227882:SAVERM_RS28225
uniprot id: Q82C87
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

227882:SAVERM RS03630
gene id: 227882:SAVERM_RS03630
uniprot id: Q82Q92
names: Similarity
messages: Belongs to the glycosyl hydrolase 27 family.

227882:SAVERM RS05900
gene id: 227882:SAVERM_RS05900
uniprot id: Q82P52
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

227882:SAVERM RS31770
gene id: 227882:SAVERM_RS31770
uniprot id: Q82A88
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

227882:SAVERM RS16315
gene id: 227882:SAVERM_RS16315
uniprot id: Q82II6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

227882:SAVERM RS32205
gene id: 227882:SAVERM_RS32205
uniprot id: Q82A00
names: Subcellular Location Annotation
messages: Membrane

227882:SAVERM RS07445
gene id: 227882:SAVERM_RS07445
uniprot id: Q82NA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

227882:SAVERM RS25480
gene id: 227882:SAVERM_RS25480
uniprot id: Q82DN4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

227882:SAVERM RS32475
gene id: 227882:SAVERM_RS32475
uniprot id: Q829U6
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

227882:SAVERM RS25270
gene id: 227882:SAVERM_RS25270
uniprot id: Q82DS1
names: Similarity
messages: Belongs to the peptidase M20A family.

227882:SAVERM RS17180
gene id: 227882:SAVERM_RS17180
uniprot id: Q82I40
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

227882:SAVERM RS23045
gene id: 227882:SAVERM_RS23045
uniprot id: Q82F01
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

227882:SAVERM RS24750
gene id: 227882:SAVERM_RS24750
uniprot id: Q82E21
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

227882:SAVERM RS12705
gene id: 227882:SAVERM_RS12705
uniprot id: Q82KG8
names: Subcellular Location Annotation
messages: Cytoplasm

227882:SAVERM RS26555
gene id: 227882:SAVERM_RS26555
uniprot id: Q82D39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

227882:SAVERM RS33410
gene id: 227882:SAVERM_RS33410
uniprot id: Q829B4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.

227882:SAVERM RS17765
gene id: 227882:SAVERM_RS17765
uniprot id: Q82HS4
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

227882:SAVERM RS31290
gene id: 227882:SAVERM_RS31290
uniprot id: Q82AI3
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

227882:SAVERM RS07060
gene id: 227882:SAVERM_RS07060
uniprot id: Q82NI4
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane

227882:SAVERM RS27655
gene id: 227882:SAVERM_RS27655
uniprot id: Q82CI8
names: Subcellular Location Annotation
messages: Membrane

227882:SAVERM RS14880
gene id: 227882:SAVERM_RS14880
uniprot id: Q82JA2
names: Subcellular Location Annotation
messages: Membrane

227882:SAVERM RS29510
gene id: 227882:SAVERM_RS29510
uniprot id: Q82BI5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

227882:SAVERM RS28135
gene id: 227882:SAVERM_RS28135
uniprot id: Q820F8
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

227882:SAVERM RS33915
gene id: 227882:SAVERM_RS33915
uniprot id: Q828R2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

227882:SAVERM RS06595
gene id: 227882:SAVERM_RS06595
uniprot id: Q82NR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

227882:SAVERM RS20510
gene id: 227882:SAVERM_RS20510
uniprot id: Q82GC3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

227882:SAVERM RS28880
gene id: 227882:SAVERM_RS28880
uniprot id: Q82BV7
names: Subcellular Location Annotation
messages: Membrane

227882:SAVERM RS37055
gene id: 227882:SAVERM_RS37055
uniprot id: Q826I0
names: Similarity
messages: Belongs to the NtaA/SnaA/DszA monooxygenase family.

227882:SAVERM RS30280
gene id: 227882:SAVERM_RS30280
uniprot id: Q82B30
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

227882:SAVERM RS24650
gene id: 227882:SAVERM_RS24650
uniprot id: Q82E42
names: Subcellular Location Annotation
messages: Membrane

227882:SAVERM RS10760
gene id: 227882:SAVERM_RS10760
uniprot id: Q82LG4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 independent methionine synthase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.

227882:SAVERM RS28680
gene id: 227882:SAVERM_RS28680
uniprot id: Q82BZ8
names: Similarity
messages: Belongs to the arylamine N-acetyltransferase family.

227882:SAVERM RS20190
gene id: 227882:SAVERM_RS20190
uniprot id: Q82GI5
names: Similarity
messages: Belongs to the helicase family. RAD25/XPB subfamily.

227882:SAVERM RS08540
gene id: 227882:SAVERM_RS08540
uniprot id: Q82MP9
names: Similarity
messages: Belongs to the cytochrome P450 family.

227882:SAVERM RS15415
gene id: 227882:SAVERM_RS15415
uniprot id: Q82J17
names: Similarity
messages: Belongs to the glycosyl hydrolase 25 family.

227882:SAVERM RS36360
gene id: 227882:SAVERM_RS36360
uniprot id: Q826U8
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

227882:SAVERM RS26450
gene id: 227882:SAVERM_RS26450
uniprot id: Q82D57
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

227882:SAVERM RS14965
gene id: 227882:SAVERM_RS14965
uniprot id: Q82J85
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

227882:SAVERM RS13135
gene id: 227882:SAVERM_RS13135
uniprot id: Q82K87
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

227882:SAVERM RS06220
gene id: 227882:SAVERM_RS06220
uniprot id: Q82NZ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

227882:SAVERM RS13605
gene id: 227882:SAVERM_RS13605
uniprot id: Q82JZ2
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

227882:SAVERM RS13745
gene id: 227882:SAVERM_RS13745
uniprot id: Q82JW4
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

227882:SAVERM RS35335
gene id: 227882:SAVERM_RS35335
uniprot id: Q827P9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

227882:SAVERM RS23990
gene id: 227882:SAVERM_RS23990
uniprot id: Q82EG9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

227882:SAVERM RS12025
gene id: 227882:SAVERM_RS12025
uniprot id: Q82KS2
names: Subcellular Location Annotation
messages: Membrane

227882:SAVERM RS34450
gene id: 227882:SAVERM_RS34450
uniprot id: Q828G3
names: Similarity
messages: Belongs to the cytochrome P450 family.

227882:SAVERM RS27800
gene id: 227882:SAVERM_RS27800
uniprot id: Q82CG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

227882:SAVERM RS24365
gene id: 227882:SAVERM_RS24365
uniprot id: Q82E95
names: Subcellular Location Annotation
messages: Membrane

227882:SAVERM RS21785
gene id: 227882:SAVERM_RS21785
uniprot id: Q82FP0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

227882:SAVERM RS27375
gene id: 227882:SAVERM_RS27375
uniprot id: Q82CP1
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

227882:SAVERM RS07240
gene id: 227882:SAVERM_RS07240
uniprot id: Q82NE9
names: Subcellular Location Annotation
messages: Membrane

227882:SAVERM RS31690
gene id: 227882:SAVERM_RS31690
uniprot id: Q82AA5
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

227882:SAVERM RS31235
gene id: 227882:SAVERM_RS31235
uniprot id: Q82AJ4
names: Similarity
messages: Belongs to the peptidase C40 family.

227882:SAVERM RS30720
gene id: 227882:SAVERM_RS30720
uniprot id: Q82AU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

227882:SAVERM RS14290
gene id: 227882:SAVERM_RS14290
uniprot id: Q82JL2
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

227882:SAVERM RS34345
gene id: 227882:SAVERM_RS34345
uniprot id: Q828I4
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the Pup ligase/Pup deamidase family. Pup-conjugating enzyme subfamily.
messages: Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine.
messages: The reaction mechanism probably proceeds via the activation of Pup by phosphorylation of its C-terminal glutamate, which is then subject to nucleophilic attack by the substrate lysine, resulting in an isopeptide bond and the release of phosphate as a good leaving group.

227882:SAVERM RS23780
gene id: 227882:SAVERM_RS23780
uniprot id: Q82EL0
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

227882:SAVERM RS28950
gene id: 227882:SAVERM_RS28950
uniprot id: Q82BU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

227882:SAVERM RS13325
gene id: 227882:SAVERM_RS13325
uniprot id: Q82K50
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

227882:SAVERM RS05290
gene id: 227882:SAVERM_RS05290
uniprot id: Q82PG0
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

227882:SAVERM RS36675
gene id: 227882:SAVERM_RS36675
uniprot id: Q826P2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

227882:SAVERM RS37070
gene id: 227882:SAVERM_RS37070
uniprot id: Q826H7
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

227882:SAVERM RS12525
gene id: 227882:SAVERM_RS12525
uniprot id: Q82KK4
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

227882:SAVERM RS24580
gene id: 227882:SAVERM_RS24580
uniprot id: Q82E56
names: Subcellular Location Annotation
messages: Membrane

227882:SAVERM RS35770
gene id: 227882:SAVERM_RS35770
uniprot id: Q827G0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

227882:SAVERM RS35455
gene id: 227882:SAVERM_RS35455
uniprot id: Q827M4
names: Subcellular Location Annotation
messages: Membrane

227882:SAVERM RS05630
gene id: 227882:SAVERM_RS05630
uniprot id: Q82PA5
names: Similarity
messages: Belongs to the bacterial solute-binding protein 1 family.

227882:SAVERM RS09520
gene id: 227882:SAVERM_RS09520
uniprot id: Q82M55
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

227882:SAVERM RS17995
gene id: 227882:SAVERM_RS17995
uniprot id: Q82HM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Membrane

227882:SAVERM RS14415
gene id: 227882:SAVERM_RS14415
uniprot id: Q82JI6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

227882:SAVERM RS11720
gene id: 227882:SAVERM_RS11720
uniprot id: Q82KX6
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

227882:SAVERM RS29830
gene id: 227882:SAVERM_RS29830
uniprot id: Q82BC0
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

227882:SAVERM RS08005
gene id: 227882:SAVERM_RS08005
uniprot id: Q82MZ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

227882:SAVERM RS33870
gene id: 227882:SAVERM_RS33870
uniprot id: Q828S1
names: Subcellular Location Annotation
messages: Membrane

227882:SAVERM RS38540
gene id: 227882:SAVERM_RS38540
uniprot id: Q825F0
names: Function
names: Similarity
messages: Abolishes the inhibitory effect of tetracyclin on protein synthesis by a non-covalent modification of the ribosomes.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.

227882:SAVERM RS30540
gene id: 227882:SAVERM_RS30540
uniprot id: Q82AY2
names: Subcellular Location Annotation
messages: Cell membrane

227882:SAVERM RS11005
gene id: 227882:SAVERM_RS11005
uniprot id: Q82LB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

227882:SAVERM RS33890
gene id: 227882:SAVERM_RS33890
uniprot id: Q828R7
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

227882:SAVERM RS22665
gene id: 227882:SAVERM_RS22665
uniprot id: Q82F79
names: Similarity
messages: Belongs to the LOR family.

227882:SAVERM RS31230
gene id: 227882:SAVERM_RS31230
uniprot id: Q82AJ5
names: Similarity
messages: Belongs to the peptidase C40 family.

227882:SAVERM RS25205
gene id: 227882:SAVERM_RS25205
uniprot id: Q82DT3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

227882:SAVERM RS02650
gene id: 227882:SAVERM_RS02650
uniprot id: Q82QT1
names: Similarity
names: Subunit
messages: Belongs to the sigma-70 factor family. ECF subfamily.
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

227882:SAVERM RS20385
gene id: 227882:SAVERM_RS20385
uniprot id: Q82GE7
names: Similarity
messages: Belongs to the Nudix hydrolase family.

227882:SAVERM RS26315
gene id: 227882:SAVERM_RS26315
uniprot id: Q82D82
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF2.
messages: Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.

227882:SAVERM RS12240
gene id: 227882:SAVERM_RS12240
uniprot id: Q82KN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

227882:SAVERM RS24270
gene id: 227882:SAVERM_RS24270
uniprot id: Q82EB3
names: Subcellular Location Annotation
messages: Membrane

227882:SAVERM RS05075
gene id: 227882:SAVERM_RS05075
uniprot id: Q82PI3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpA family.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds the extracellular potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

227882:SAVERM RS22160
gene id: 227882:SAVERM_RS22160
uniprot id: Q82FG6
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

227882:SAVERM RS24010
gene id: 227882:SAVERM_RS24010
uniprot id: Q82EG5
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

227882:SAVERM RS23760
gene id: 227882:SAVERM_RS23760
uniprot id: Q82EL4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Catalyzes the reversible hydration of carbon dioxide to form bicarbonate.
messages: Membrane

227882:SAVERM RS31215
gene id: 227882:SAVERM_RS31215
uniprot id: Q82AJ8
names: Subcellular Location Annotation
messages: Membrane

227882:SAVERM RS23965
gene id: 227882:SAVERM_RS23965
uniprot id: Q82EH4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

227882:SAVERM RS35125
gene id: 227882:SAVERM_RS35125
uniprot id: Q820F4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

227882:SAVERM RS07070
gene id: 227882:SAVERM_RS07070
uniprot id: Q82NI2
names: Similarity
messages: Belongs to the UPF0166 family.

227882:SAVERM RS19930
gene id: 227882:SAVERM_RS19930
uniprot id: Q82GN9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
messages: Homodimer.

227882:SAVERM RS16440
gene id: 227882:SAVERM_RS16440
uniprot id: Q82IH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

227882:SAVERM RS07325
gene id: 227882:SAVERM_RS07325
uniprot id: Q82ND1
names: Similarity
messages: Belongs to the TPP enzyme family.

227882:SAVERM RS13925
gene id: 227882:SAVERM_RS13925
uniprot id: Q82JS9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

227882:SAVERM RS02965
gene id: 227882:SAVERM_RS02965
uniprot id: Q82QK9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

227882:SAVERM RS03615
gene id: 227882:SAVERM_RS03615
uniprot id: Q82Q95
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

227882:SAVERM RS16745
gene id: 227882:SAVERM_RS16745
uniprot id: Q82IC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

227882:SAVERM RS19760
gene id: 227882:SAVERM_RS19760
uniprot id: Q82GS3
names: Cofactor
names: Similarity
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.

227882:SAVERM RS25540
gene id: 227882:SAVERM_RS25540
uniprot id: P60516
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

227882:SAVERM RS15505
gene id: 227882:SAVERM_RS15505
uniprot id: Q82IZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

227882:SAVERM RS22290
gene id: 227882:SAVERM_RS22290
uniprot id: P59811
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration (By similarity).
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins (By similarity).

227882:SAVERM RS19990
gene id: 227882:SAVERM_RS19990
uniprot id: Q82GM7
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

227882:SAVERM RS23855
gene id: 227882:SAVERM_RS23855
uniprot id: Q82EJ4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

227882:SAVERM RS17495
gene id: 227882:SAVERM_RS17495
uniprot id: Q82HX5
names: Subunit
messages: Heterodimer of an alpha and a beta chain.

227882:SAVERM RS14225
gene id: 227882:SAVERM_RS14225
uniprot id: Q82JM4
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

227882:SAVERM RS30790
gene id: 227882:SAVERM_RS30790
uniprot id: Q82AT2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

227882:SAVERM RS12510
gene id: 227882:SAVERM_RS12510
uniprot id: Q82KK7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

227882:SAVERM RS32245
gene id: 227882:SAVERM_RS32245
uniprot id: Q829Z2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pseudouridine-5'-phosphate glycosidase family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the reversible cleavage of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway.
messages: Homotrimer.

227882:SAVERM RS32260
gene id: 227882:SAVERM_RS32260
uniprot id: Q829Y9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

227882:SAVERM RS37970
gene id: 227882:SAVERM_RS37970
uniprot id: Q825R0
names: Similarity
names: Subunit
messages: Belongs to the aminoglycoside phosphotransferase family.
messages: Monomer.

227882:SAVERM RS22465
gene id: 227882:SAVERM_RS22465
uniprot id: Q82FB5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
messages: Belongs to the azoreductase type 1 family.
messages: Binds 1 FMN per subunit.
messages: Homodimer.
messages: Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones.

227882:SAVERM RS04130
gene id: 227882:SAVERM_RS04130
uniprot id: Q82PZ2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

227882:SAVERM RS36630
gene id: 227882:SAVERM_RS36630
uniprot id: Q79Z24
names: Similarity
messages: Belongs to the thiolase-like superfamily. Chalcone/stilbene synthases family.

227882:SAVERM RS09500
gene id: 227882:SAVERM_RS09500
uniprot id: Q82M59
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

227882:SAVERM RS25490
gene id: 227882:SAVERM_RS25490
uniprot id: P66418
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

227882:SAVERM RS20040
gene id: 227882:SAVERM_RS20040
uniprot id: Q82GL5
names: Similarity
messages: Belongs to the cytochrome P450 family.

227882:SAVERM RS09140
gene id: 227882:SAVERM_RS09140
uniprot id: Q82MD0
names: Similarity
messages: Belongs to the proline racemase family.

227882:SAVERM RS23385
gene id: 227882:SAVERM_RS23385
uniprot id: Q82ET6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the kynureninase family.
messages: Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

227882:SAVERM RS34630
gene id: 227882:SAVERM_RS34630
uniprot id: Q828C6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

227882:SAVERM RS06340
gene id: 227882:SAVERM_RS06340
uniprot id: Q82NX0
names: Similarity
messages: Belongs to the cytochrome P450 family.

227882:SAVERM RS34865
gene id: 227882:SAVERM_RS34865
uniprot id: Q827X9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

227882:SAVERM RS37175
gene id: 227882:SAVERM_RS37175
uniprot id: Q826F6
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock (By similarity).

227882:SAVERM RS20045
gene id: 227882:SAVERM_RS20045
uniprot id: Q82GL4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

227882:SAVERM RS21025
gene id: 227882:SAVERM_RS21025
uniprot id: Q82G17
names: Similarity
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.

227882:SAVERM RS14385
gene id: 227882:SAVERM_RS14385
uniprot id: Q82JJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

227882:SAVERM RS05830
gene id: 227882:SAVERM_RS05830
uniprot id: Q82P66
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

227882:SAVERM RS03990
gene id: 227882:SAVERM_RS03990
uniprot id: Q82Q22
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

227882:SAVERM RS38115
gene id: 227882:SAVERM_RS38115
uniprot id: Q825N1
names: Similarity
messages: Belongs to the cytochrome P450 family.

227882:SAVERM RS08630
gene id: 227882:SAVERM_RS08630
uniprot id: Q82MN2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the zinc-containing alcohol dehydrogenase family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate.
messages: Cytoplasm
messages: Homotetramer.

227882:SAVERM RS05860
gene id: 227882:SAVERM_RS05860
uniprot id: Q82P60
names: Subcellular Location Annotation
messages: Membrane

227882:SAVERM RS19810
gene id: 227882:SAVERM_RS19810
uniprot id: Q82GR3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

227882:SAVERM RS16835
gene id: 227882:SAVERM_RS16835
uniprot id: Q82IA6
names: Subcellular Location Annotation
messages: Membrane

227882:SAVERM RS36990
gene id: 227882:SAVERM_RS36990
uniprot id: Q826J2
names: Activity Regulation
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.

227882:SAVERM RS21605
gene id: 227882:SAVERM_RS21605
uniprot id: Q82FS2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

227882:SAVERM RS44710
gene id: 227882:SAVERM_RS44710
uniprot id: Q82K10
names: Subcellular Location Annotation
messages: Membrane

227882:SAVERM RS11335
gene id: 227882:SAVERM_RS11335
uniprot id: Q82L53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 13 family.
messages: Cytoplasm

227882:SAVERM RS12645
gene id: 227882:SAVERM_RS12645
uniprot id: Q82KI0
names: Similarity
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.

227882:SAVERM RS19655
gene id: 227882:SAVERM_RS19655
uniprot id: Q82GU2
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

227882:SAVERM RS27860
gene id: 227882:SAVERM_RS27860
uniprot id: Q82CF3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

227882:SAVERM RS02515
gene id: 227882:SAVERM_RS02515
uniprot id: Q82QU2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PNT beta subunit family.
messages: Cell inner membrane
messages: Membrane
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

227882:SAVERM RS05225
gene id: 227882:SAVERM_RS05225
uniprot id: Q79ZM2
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

227882:SAVERM RS35390
gene id: 227882:SAVERM_RS35390
uniprot id: Q827N8
names: Subcellular Location Annotation
messages: Membrane

227882:SAVERM RS21975
gene id: 227882:SAVERM_RS21975
uniprot id: Q82FK3
names: Subcellular Location Annotation
messages: Membrane

227882:SAVERM RS18265
gene id: 227882:SAVERM_RS18265
uniprot id: Q82HH3
names: Similarity
messages: Belongs to the transglycosylase family. Rpf subfamily.

227882:SAVERM RS28895
gene id: 227882:SAVERM_RS28895
uniprot id: Q82BV4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M4 family.
messages: Extracellular zinc metalloprotease.
messages: Secreted

227882:SAVERM RS00790
gene id: 227882:SAVERM_RS00790
uniprot id: Q82RS1
names: Subcellular Location Annotation
messages: Cell membrane

227882:SAVERM RS12710
gene id: 227882:SAVERM_RS12710
uniprot id: Q82KG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

227882:SAVERM RS36885
gene id: 227882:SAVERM_RS36885
uniprot id: Q79Z15
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Catalyzes the phosphorylation of D-xylulose to D-xylulose 5-phosphate.

227882:SAVERM RS33535
gene id: 227882:SAVERM_RS33535
uniprot id: Q828Y9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

227882:SAVERM RS32390
gene id: 227882:SAVERM_RS32390
uniprot id: Q829W3
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
messages: Catalyzes the oxidative phosphorylation of glyceraldehyde 3-phosphate (G3P) to 1,3-bisphosphoglycerate (BPG) using the cofactor NAD. The first reaction step involves the formation of a hemiacetal intermediate between G3P and a cysteine residue, and this hemiacetal intermediate is then oxidized to a thioester, with concomitant reduction of NAD to NADH. The reduced NADH is then exchanged with the second NAD, and the thioester is attacked by a nucleophilic inorganic phosphate to produce BPG.
messages: Cytoplasm
messages: Homotetramer.
messages: Inhibited by pentalenolactone.

227882:SAVERM RS05265
gene id: 227882:SAVERM_RS05265
uniprot id: Q82PG6
names: Similarity
messages: Belongs to the TPP enzyme family.

227882:SAVERM RS14980
gene id: 227882:SAVERM_RS14980
uniprot id: Q82J82
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

227882:SAVERM RS27970
gene id: 227882:SAVERM_RS27970
uniprot id: Q82CD2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

227882:SAVERM RS08995
gene id: 227882:SAVERM_RS08995
uniprot id: Q82MF9
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

227882:SAVERM RS14840
gene id: 227882:SAVERM_RS14840
uniprot id: Q82JB0
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

227882:SAVERM RS28780
gene id: 227882:SAVERM_RS28780
uniprot id: Q82BX7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenine deaminase type 2 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism.

227882:SAVERM RS32090
gene id: 227882:SAVERM_RS32090
uniprot id: Q82A24
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

227882:SAVERM RS23480
gene id: 227882:SAVERM_RS23480
uniprot id: Q82ER9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial microcompartment
messages: Belongs to the EutB family.
messages: Binds between the large and small subunits.
messages: Catalyzes the deamination of various vicinal amino-alcohols to oxo compounds. Allows this organism to utilize ethanolamine as the sole source of nitrogen and carbon in the presence of vitamin B12.
messages: The basic unit is a heterodimer which dimerizes to form tetramers. The heterotetramers trimerize; 6 large subunits form a core ring with 6 small subunits projecting outwards.

227882:SAVERM RS33605
gene id: 227882:SAVERM_RS33605
uniprot id: Q828X4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with subunits II, III and IV to form cytochrome c oxidase.
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Binds 1 copper B ion per subunit.
messages: Binds 2 heme groups per subunit.
messages: Cell membrane
messages: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B (By similarity).

227882:SAVERM RS17680
gene id: 227882:SAVERM_RS17680
uniprot id: Q82HU1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.

227882:SAVERM RS30690
gene id: 227882:SAVERM_RS30690
uniprot id: Q82AV1
names: Similarity
messages: Belongs to the glutamine synthetase family.

227882:SAVERM RS28745
gene id: 227882:SAVERM_RS28745
uniprot id: Q82BY4
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

227882:SAVERM RS07520
gene id: 227882:SAVERM_RS07520
uniprot id: Q82N92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

227882:SAVERM RS38345
gene id: 227882:SAVERM_RS38345
uniprot id: Q825I8
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the cytochrome P450 family.
messages: Catalyzes the conversion of 1-deoxypentalenic acid to pentalenic acid in the biosynthesis of neopentalenolactone antibiotic.
messages: S.avermitilis does not produce pentalenolactone itself in vivo but instead a group of new metabolites that are neopentalenolactone derivatives.

227882:SAVERM RS04460
gene id: 227882:SAVERM_RS04460
uniprot id: Q82PS1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 2 subfamily.
messages: Cytoplasm
messages: Homotetramer.

227882:SAVERM RS35350
gene id: 227882:SAVERM_RS35350
uniprot id: Q827P6
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

227882:SAVERM RS13985
gene id: 227882:SAVERM_RS13985
uniprot id: Q82JR8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

227882:SAVERM RS24965
gene id: 227882:SAVERM_RS24965
uniprot id: Q82DY0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

227882:SAVERM RS22700
gene id: 227882:SAVERM_RS22700
uniprot id: Q82F71
names: Similarity
messages: Belongs to the pirin family.

227882:SAVERM RS07350
gene id: 227882:SAVERM_RS07350
uniprot id: Q82NC5
names: Subcellular Location Annotation
messages: Membrane

227882:SAVERM RS25185
gene id: 227882:SAVERM_RS25185
uniprot id: Q82DT7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

227882:SAVERM RS29740
gene id: 227882:SAVERM_RS29740
uniprot id: Q82BD8
names: Subcellular Location Annotation
messages: Membrane

227882:SAVERM RS12110
gene id: 227882:SAVERM_RS12110
uniprot id: Q82KQ7
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

227882:SAVERM RS25525
gene id: 227882:SAVERM_RS25525
uniprot id: Q82DM6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

227882:SAVERM RS08570
gene id: 227882:SAVERM_RS08570
uniprot id: Q82MP3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class II aldolase/RraA-like family.
messages: Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2-oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions.
messages: Homotrimer.

227882:SAVERM RS33135
gene id: 227882:SAVERM_RS33135
uniprot id: Q829G6
names: Subcellular Location Annotation
messages: Membrane

227882:SAVERM RS26575
gene id: 227882:SAVERM_RS26575
uniprot id: Q53586
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the 4HPPD family.
messages: Binds 1 Fe cation per subunit.
messages: Homodimer.

227882:SAVERM RS07560
gene id: 227882:SAVERM_RS07560
uniprot id: Q82N84
names: Similarity
messages: Belongs to the CdaR family.

227882:SAVERM RS32550
gene id: 227882:SAVERM_RS32550
uniprot id: Q829T1
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

227882:SAVERM RS23365
gene id: 227882:SAVERM_RS23365
uniprot id: Q82EU0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.

227882:SAVERM RS26160
gene id: 227882:SAVERM_RS26160
uniprot id: Q82DB1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

227882:SAVERM RS04740
gene id: 227882:SAVERM_RS04740
uniprot id: Q79ZP6
names: Cofactor
names: Similarity
messages: Belongs to the peptidase S45 family.
messages: Binds 1 Ca(2+) ion per dimer.

227882:SAVERM RS08720
gene id: 227882:SAVERM_RS08720
uniprot id: Q82ML4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

227882:SAVERM RS36520
gene id: 227882:SAVERM_RS36520
uniprot id: Q826R6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UreD family.
messages: Cytoplasm
messages: Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
messages: UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

227882:SAVERM RS24480
gene id: 227882:SAVERM_RS24480
uniprot id: Q82E76
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

227882:SAVERM RS03255
gene id: 227882:SAVERM_RS03255
uniprot id: Q82QF6
names: Subcellular Location Annotation
messages: Membrane

227882:SAVERM RS26030
gene id: 227882:SAVERM_RS26030
uniprot id: Q82DD4
names: Similarity
messages: Belongs to the phosphohexose mutase family.

227882:SAVERM RS13755
gene id: 227882:SAVERM_RS13755
uniprot id: Q82JW2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein S19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein S19.

227882:SAVERM RS11080
gene id: 227882:SAVERM_RS11080
uniprot id: Q82LA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polysaccharide lyase 4 family.
messages: Secreted

227882:SAVERM RS28270
gene id: 227882:SAVERM_RS28270
uniprot id: Q82C78
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

227882:SAVERM RS35415
gene id: 227882:SAVERM_RS35415
uniprot id: Q827N2
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

227882:SAVERM RS08670
gene id: 227882:SAVERM_RS08670
uniprot id: Q82MM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
messages: Cytoplasm

227882:SAVERM RS34295
gene id: 227882:SAVERM_RS34295
uniprot id: Q828J5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM61 family.
messages: Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA.
messages: Homotetramer composed of a dimer of dimers.

227882:SAVERM RS12795
gene id: 227882:SAVERM_RS12795
uniprot id: Q82KF0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

227882:SAVERM RS23555
gene id: 227882:SAVERM_RS23555
uniprot id: Q82EQ5
names: Function
names: Similarity
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids lysine, threonine, isoleucine and methionine.

227882:SAVERM RS36515
gene id: 227882:SAVERM_RS36515
uniprot id: Q826R7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
messages: Cytoplasm
messages: Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
messages: Homodimer. UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

227882:SAVERM RS36590
gene id: 227882:SAVERM_RS36590
uniprot id: Q826Q3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

227882:SAVERM RS22295
gene id: 227882:SAVERM_RS22295
uniprot id: Q82FE1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

227882:SAVERM RS27950
gene id: 227882:SAVERM_RS27950
uniprot id: Q82CD6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family.
messages: Membrane

227882:SAVERM RS27450
gene id: 227882:SAVERM_RS27450
uniprot id: Q82CM7
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

227882:SAVERM RS10725
gene id: 227882:SAVERM_RS10725
uniprot id: Q82LH1
names: Subunit
messages: Heterodimer of an alpha and a beta chain.

227882:SAVERM RS30640
gene id: 227882:SAVERM_RS30640
uniprot id: Q82AW1
names: Subcellular Location Annotation
messages: Membrane

227882:SAVERM RS08480
gene id: 227882:SAVERM_RS08480
uniprot id: Q82MR0
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

227882:SAVERM RS07515
gene id: 227882:SAVERM_RS07515
uniprot id: Q82N93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

227882:SAVERM RS06755
gene id: 227882:SAVERM_RS06755
uniprot id: Q82NP4
names: Function
names: Similarity
messages: Belongs to the phenylacetyl-CoA ligase family.
messages: Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).

227882:SAVERM RS19060
gene id: 227882:SAVERM_RS19060
uniprot id: Q82H52
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

227882:SAVERM RS37875
gene id: 227882:SAVERM_RS37875
uniprot id: Q825T1
names: Similarity
messages: Belongs to the HupF/HypC family.

227882:SAVERM RS37370
gene id: 227882:SAVERM_RS37370
uniprot id: Q826B6
names: Similarity
messages: Belongs to the glycosyl hydrolase 38 family.

227882:SAVERM RS11320
gene id: 227882:SAVERM_RS11320
uniprot id: Q82L56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protease inhibitor I16 (SSI) family.
messages: Secreted

227882:SAVERM RS06460
gene id: 227882:SAVERM_RS06460
uniprot id: Q82NU6
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

227882:SAVERM RS18225
gene id: 227882:SAVERM_RS18225
uniprot id: Q82HI1
names: Subcellular Location Annotation
messages: Membrane

227882:SAVERM RS33695
gene id: 227882:SAVERM_RS33695
uniprot id: Q828V6
names: Similarity
messages: Belongs to the DNA polymerase type-C family. DnaE2 subfamily.

227882:SAVERM RS25295
gene id: 227882:SAVERM_RS25295
uniprot id: P66234
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

227882:SAVERM RS24490
gene id: 227882:SAVERM_RS24490
uniprot id: Q82E74
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

227882:SAVERM RS18410
gene id: 227882:SAVERM_RS18410
uniprot id: Q82HE6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

227882:SAVERM RS16175
gene id: 227882:SAVERM_RS16175
uniprot id: Q82IL3
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

227882:SAVERM RS07620
gene id: 227882:SAVERM_RS07620
uniprot id: Q82N72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CbxX/CfxQ family.
messages: Cytoplasm

227882:SAVERM RS32190
gene id: 227882:SAVERM_RS32190
uniprot id: Q82A03
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

227882:SAVERM RS07090
gene id: 227882:SAVERM_RS07090
uniprot id: Q82NH8
names: Similarity
messages: Belongs to the glycosyl hydrolase 42 family.

227882:SAVERM RS16655
gene id: 227882:SAVERM_RS16655
uniprot id: Q82IE2
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

227882:SAVERM RS17390
gene id: 227882:SAVERM_RS17390
uniprot id: Q82HZ7
names: Subcellular Location Annotation
messages: Membrane

227882:SAVERM RS20125
gene id: 227882:SAVERM_RS20125
uniprot id: Q82GJ8
names: Subcellular Location Annotation
messages: Cell membrane

227882:SAVERM RS34240
gene id: 227882:SAVERM_RS34240
uniprot id: Q828K5
names: Activity Regulation
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.

227882:SAVERM RS36915
gene id: 227882:SAVERM_RS36915
uniprot id: Q826K5
names: Similarity
messages: Belongs to the cytochrome P450 family.

227882:SAVERM RS25785
gene id: 227882:SAVERM_RS25785
uniprot id: Q82DH8
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

227882:SAVERM RS04415
gene id: 227882:SAVERM_RS04415
uniprot id: Q82PT1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

227882:SAVERM RS15850
gene id: 227882:SAVERM_RS15850
uniprot id: Q82IT0
names: Similarity
messages: Belongs to the Fur family.

227882:SAVERM RS35375
gene id: 227882:SAVERM_RS35375
uniprot id: Q827P1
names: Similarity
messages: Belongs to the barstar family.

227882:SAVERM RS35705
gene id: 227882:SAVERM_RS35705
uniprot id: Q827H3
names: Similarity
messages: Belongs to the GcvT family.

227882:SAVERM RS16605
gene id: 227882:SAVERM_RS16605
uniprot id: Q82IF2
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

227882:SAVERM RS17905
gene id: 227882:SAVERM_RS17905
uniprot id: Q82HP5
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

227882:SAVERM RS09145
gene id: 227882:SAVERM_RS09145
uniprot id: Q82MC9
names: Similarity
messages: Belongs to the DapA family.

227882:SAVERM RS21010
gene id: 227882:SAVERM_RS21010
uniprot id: Q82G20
names: Similarity
messages: Belongs to the CsoR family.

227882:SAVERM RS31045
gene id: 227882:SAVERM_RS31045
uniprot id: Q82AN2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

227882:SAVERM RS11950
gene id: 227882:SAVERM_RS11950
uniprot id: Q79ZH2
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

227882:SAVERM RS18870
gene id: 227882:SAVERM_RS18870
uniprot id: Q93HC3
names: Function
names: PTM
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of the apo-ACP-like protein.
messages: Acyl carrier protein.

227882:SAVERM RS32835
gene id: 227882:SAVERM_RS32835
uniprot id: Q829M6
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

227882:SAVERM RS30115
gene id: 227882:SAVERM_RS30115
uniprot id: Q82B64
names: Similarity
messages: Belongs to the cytochrome P450 family.

227882:SAVERM RS24455
gene id: 227882:SAVERM_RS24455
uniprot id: Q82E81
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

227882:SAVERM RS16030
gene id: 227882:SAVERM_RS16030
uniprot id: Q82IP5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

227882:SAVERM RS09380
gene id: 227882:SAVERM_RS09380
uniprot id: Q82M83
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).

227882:SAVERM RS30620
gene id: 227882:SAVERM_RS30620
uniprot id: Q82AW5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

227882:SAVERM RS24040
gene id: 227882:SAVERM_RS24040
uniprot id: Q82EF9
names: Subcellular Location Annotation
messages: Membrane

227882:SAVERM RS34810
gene id: 227882:SAVERM_RS34810
uniprot id: Q827Z0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

227882:SAVERM RS14670
gene id: 227882:SAVERM_RS14670
uniprot id: Q82JD5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

227882:SAVERM RS35460
gene id: 227882:SAVERM_RS35460
uniprot id: Q827M3
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

227882:SAVERM RS32300
gene id: 227882:SAVERM_RS32300
uniprot id: Q829Y1
names: Subcellular Location Annotation
messages: Membrane

227882:SAVERM RS31565
gene id: 227882:SAVERM_RS31565
uniprot id: Q82AD0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DivIVA family.
messages: Cytoplasm

227882:SAVERM RS13980
gene id: 227882:SAVERM_RS13980
uniprot id: Q82JR9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

227882:SAVERM RS20475
gene id: 227882:SAVERM_RS20475
uniprot id: Q82GD0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

227882:SAVERM RS24125
gene id: 227882:SAVERM_RS24125
uniprot id: Q82EE2
names: Subcellular Location Annotation
messages: Membrane

227882:SAVERM RS33635
gene id: 227882:SAVERM_RS33635
uniprot id: Q828W8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SepF family.
messages: Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
messages: Cytoplasm
messages: Homodimer. Interacts with FtsZ.

227882:SAVERM RS34005
gene id: 227882:SAVERM_RS34005
uniprot id: Q828P4
names: Subcellular Location Annotation
messages: Membrane

227882:SAVERM RS31765
gene id: 227882:SAVERM_RS31765
uniprot id: Q82A89
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRA-CH family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
messages: Cytoplasm
messages: Homodimer.

227882:SAVERM RS32465
gene id: 227882:SAVERM_RS32465
uniprot id: Q829U8
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

227882:SAVERM RS16575
gene id: 227882:SAVERM_RS16575
uniprot id: Q79Z91
names: Similarity
messages: Belongs to the thioesterase family.

227882:SAVERM RS12560
gene id: 227882:SAVERM_RS12560
uniprot id: Q82KJ7
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

227882:SAVERM RS18630
gene id: 227882:SAVERM_RS18630
uniprot id: Q82HA3
names: Subcellular Location Annotation
messages: Membrane

227882:SAVERM RS23495
gene id: 227882:SAVERM_RS23495
uniprot id: Q82ER6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

227882:SAVERM RS15985
gene id: 227882:SAVERM_RS15985
uniprot id: Q82IQ4
names: Subcellular Location Annotation
messages: Membrane

227882:SAVERM RS33205
gene id: 227882:SAVERM_RS33205
uniprot id: Q829F2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

227882:SAVERM RS21690
gene id: 227882:SAVERM_RS21690
uniprot id: Q82FQ7
names: Subcellular Location Annotation
messages: Membrane

227882:SAVERM RS11500
gene id: 227882:SAVERM_RS11500
uniprot id: Q82L20
names: Function
names: Similarity
messages: Belongs to the ApbE family.
messages: Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.

227882:SAVERM RS20485
gene id: 227882:SAVERM_RS20485
uniprot id: Q82GC8
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

227882:SAVERM RS11735
gene id: 227882:SAVERM_RS11735
uniprot id: Q82KX3
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.

227882:SAVERM RS09860
gene id: 227882:SAVERM_RS09860
uniprot id: Q82LZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

227882:SAVERM RS16335
gene id: 227882:SAVERM_RS16335
uniprot id: Q82II5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

227882:SAVERM RS14435
gene id: 227882:SAVERM_RS14435
uniprot id: Q82JI2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

227882:SAVERM RS31180
gene id: 227882:SAVERM_RS31180
uniprot id: Q82AK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane

227882:SAVERM RS03375
gene id: 227882:SAVERM_RS03375
uniprot id: Q82QD4
names: Function
messages: TetR is the repressor of the tetracycline resistance element; its N-terminal region forms a helix-turn-helix structure and binds DNA. Binding of tetracycline to TetR reduces the repressor affinity for the tetracycline resistance gene (tetA) promoter operator sites.

227882:SAVERM RS29710
gene id: 227882:SAVERM_RS29710
uniprot id: Q82BE4
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

227882:SAVERM RS14390
gene id: 227882:SAVERM_RS14390
uniprot id: Q82JJ1
names: Similarity
messages: Belongs to the peptidase M1 family.

227882:SAVERM RS20215
gene id: 227882:SAVERM_RS20215
uniprot id: Q82GI0
names: Similarity
messages: Belongs to the CutC family.

227882:SAVERM RS33010
gene id: 227882:SAVERM_RS33010
uniprot id: Q829J1
names: Similarity
messages: Belongs to the glycosyl hydrolase 25 family.

227882:SAVERM RS22690
gene id: 227882:SAVERM_RS22690
uniprot id: Q82F73
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

227882:SAVERM RS24955
gene id: 227882:SAVERM_RS24955
uniprot id: Q82DY2
names: Similarity
messages: Belongs to the peptidase C40 family.

227882:SAVERM RS26990
gene id: 227882:SAVERM_RS26990
uniprot id: Q82CV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

227882:SAVERM RS36655
gene id: 227882:SAVERM_RS36655
uniprot id: Q826P6
names: Function
names: Similarity
messages: Belongs to the ATP-dependent DNA ligase family.
messages: DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair.

227882:SAVERM RS12650
gene id: 227882:SAVERM_RS12650
uniprot id: Q82KH9
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

227882:SAVERM RS25190
gene id: 227882:SAVERM_RS25190
uniprot id: Q82DT6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex (By similarity).
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

227882:SAVERM RS14440
gene id: 227882:SAVERM_RS14440
uniprot id: Q82JI1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

227882:SAVERM RS33070
gene id: 227882:SAVERM_RS33070
uniprot id: Q829H9
names: Similarity
messages: Belongs to the asp23 family.

227882:SAVERM RS24520
gene id: 227882:SAVERM_RS24520
uniprot id: Q82E68
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

227882:SAVERM RS11705
gene id: 227882:SAVERM_RS11705
uniprot id: Q82KX9
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

227882:SAVERM RS31485
gene id: 227882:SAVERM_RS31485
uniprot id: Q82AE5
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Catalyzes the reversible hydration of carbon dioxide to form bicarbonate.

227882:SAVERM RS31800
gene id: 227882:SAVERM_RS31800
uniprot id: Q82A82
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

227882:SAVERM RS13650
gene id: 227882:SAVERM_RS13650
uniprot id: Q82JY3
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

227882:SAVERM RS21555
gene id: 227882:SAVERM_RS21555
uniprot id: Q82FT1
names: Cofactor
names: Similarity
messages: Belongs to the peptidase S45 family.
messages: Binds 1 Ca(2+) ion per dimer.

227882:SAVERM RS18990
gene id: 227882:SAVERM_RS18990
uniprot id: Q82H67
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Although this enzyme belongs to the family of MTA phosphorylases based on sequence homology, it lacks several conserved amino acids in the substrate binding pocket that confer specificity towards MTA.
messages: Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
messages: Homohexamer. Dimer of a homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Purine nucleoside phosphorylase involved in purine salvage.

227882:SAVERM RS16850
gene id: 227882:SAVERM_RS16850
uniprot id: Q82IA3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

227882:SAVERM RS12880
gene id: 227882:SAVERM_RS12880
uniprot id: Q82KD3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

227882:SAVERM RS17515
gene id: 227882:SAVERM_RS17515
uniprot id: Q82HX2
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

227882:SAVERM RS37195
gene id: 227882:SAVERM_RS37195
uniprot id: Q826F2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent (By similarity).
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK (By similarity).
messages: The Clp repeat (R) domain probably functions as a substrate-discriminating domain, recruiting aggregated proteins to the ClpB hexamer and/or stabilizing bound proteins. The NBD2 domain is responsible for oligomerization, whereas the NBD1 domain stabilizes the hexamer probably in an ATP-dependent manner. The movement of the coiled-coil domain is essential for ClpB ability to rescue proteins from an aggregated state, probably by pulling apart large aggregated proteins, which are bound between the coiled-coils motifs of adjacent ClpB subunits in the functional hexamer (By similarity).

227882:SAVERM RS15580
gene id: 227882:SAVERM_RS15580
uniprot id: Q82IY3
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Catalyzes the conversion of pentalenene to pentalen-13-al by stepwise oxidation via pentalen-13-ol, a precursor of neopentalenolactone antibiotic.
messages: Membrane
messages: S.avermitilis does not produce pentalenolactone itself in vivo but instead a group of new metabolites that are neopentalenolactone derivatives.

227882:SAVERM RS08270
gene id: 227882:SAVERM_RS08270
uniprot id: Q82MV1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Aliphatic sulfonates importer (TC 3.A.1.17.2) family.
messages: Cell membrane
messages: Part of the ABC transporter complex SsuABC involved in aliphatic sulfonates import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (SsuB), two transmembrane proteins (SsuC) and a solute-binding protein (SsuA).

227882:SAVERM RS11015
gene id: 227882:SAVERM_RS11015
uniprot id: Q82LB5
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

227882:SAVERM RS28740
gene id: 227882:SAVERM_RS28740
uniprot id: Q82BY5
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

227882:SAVERM RS09670
gene id: 227882:SAVERM_RS09670
uniprot id: Q82M27
names: Similarity
messages: Belongs to the ketopantoate reductase family.

227882:SAVERM RS14330
gene id: 227882:SAVERM_RS14330
uniprot id: Q82JK4
names: Similarity
messages: Belongs to the LOG family.

227882:SAVERM RS03170
gene id: 227882:SAVERM_RS03170
uniprot id: Q82QG9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sirtuin family. Class II subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form.

227882:SAVERM RS17750
gene id: 227882:SAVERM_RS17750
uniprot id: Q82HS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

227882:SAVERM RS12835
gene id: 227882:SAVERM_RS12835
uniprot id: Q82KE2
names: Cofactor
names: Function
names: Similarity
messages: 5'-deoxyadenosylcobalamine (coenzyme B12).
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen (By similarity).

227882:SAVERM RS10710
gene id: 227882:SAVERM_RS10710
uniprot id: Q82LH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

227882:SAVERM RS14900
gene id: 227882:SAVERM_RS14900
uniprot id: Q82J98
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NucS endonuclease family.
messages: Cleaves both 3' and 5' ssDNA extremities of branched DNA structures.
messages: Cytoplasm

227882:SAVERM RS19080
gene id: 227882:SAVERM_RS19080
uniprot id: Q82H48
names: Subcellular Location Annotation
messages: Membrane

227882:SAVERM RS24285
gene id: 227882:SAVERM_RS24285
uniprot id: Q82EB0
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: May be involved in the stabilization of the cell envelope or may interact with the sensor protein CseC to modulate its activity, in response to cell envelope stress.

227882:SAVERM RS16450
gene id: 227882:SAVERM_RS16450
uniprot id: Q82IH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

227882:SAVERM RS32710
gene id: 227882:SAVERM_RS32710
uniprot id: Q829P9
names: Similarity
messages: Belongs to the DapA family.

227882:SAVERM RS26875
gene id: 227882:SAVERM_RS26875
uniprot id: Q82CY0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

227882:SAVERM RS24195
gene id: 227882:SAVERM_RS24195
uniprot id: Q82EC8
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

227882:SAVERM RS24780
gene id: 227882:SAVERM_RS24780
uniprot id: Q82E15
names: Subcellular Location Annotation
messages: Membrane

227882:SAVERM RS26475
gene id: 227882:SAVERM_RS26475
uniprot id: Q82D52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

227882:SAVERM RS12130
gene id: 227882:SAVERM_RS12130
uniprot id: Q82KQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arginine deiminase family.
messages: Cytoplasm

227882:SAVERM RS33895
gene id: 227882:SAVERM_RS33895
uniprot id: Q828R6
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

227882:SAVERM RS31975
gene id: 227882:SAVERM_RS31975
uniprot id: Q82A46
names: Similarity
messages: Belongs to the group II decarboxylase family.

227882:SAVERM RS10735
gene id: 227882:SAVERM_RS10735
uniprot id: Q82LG9
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

227882:SAVERM RS16115
gene id: 227882:SAVERM_RS16115
uniprot id: Q82IM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

227882:SAVERM RS25565
gene id: 227882:SAVERM_RS25565
uniprot id: Q82DM2
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

227882:SAVERM RS09590
gene id: 227882:SAVERM_RS09590
uniprot id: Q82M43
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

227882:SAVERM RS24660
gene id: 227882:SAVERM_RS24660
uniprot id: Q82E40
names: Subcellular Location Annotation
messages: Cytoplasm

227882:SAVERM RS10595
gene id: 227882:SAVERM_RS10595
uniprot id: Q82LJ7
names: Subcellular Location Annotation
messages: Membrane

227882:SAVERM RS33630
gene id: 227882:SAVERM_RS33630
uniprot id: Q828W9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

227882:SAVERM RS13505
gene id: 227882:SAVERM_RS13505
uniprot id: Q82K12
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

227882:SAVERM RS06120
gene id: 227882:SAVERM_RS06120
uniprot id: Q82P07
names: Similarity
messages: Belongs to the FGGY kinase family.

227882:SAVERM RS11260
gene id: 227882:SAVERM_RS11260
uniprot id: Q82L67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

227882:SAVERM RS24475
gene id: 227882:SAVERM_RS24475
uniprot id: Q82E77
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

227882:SAVERM RS06810
gene id: 227882:SAVERM_RS06810
uniprot id: Q82NN5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

227882:SAVERM RS37965
gene id: 227882:SAVERM_RS37965
uniprot id: Q825R1
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family. TreS subfamily.

227882:SAVERM RS35315
gene id: 227882:SAVERM_RS35315
uniprot id: Q827Q3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

227882:SAVERM RS35765
gene id: 227882:SAVERM_RS35765
uniprot id: Q827G1
names: Activity Regulation
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.

227882:SAVERM RS17400
gene id: 227882:SAVERM_RS17400
uniprot id: Q82HZ5
names: Similarity
names: Subunit
messages: Belongs to the sigma-70 factor family. ECF subfamily.
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

227882:SAVERM RS27980
gene id: 227882:SAVERM_RS27980
uniprot id: Q82CD0
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

227882:SAVERM RS25970
gene id: 227882:SAVERM_RS25970
uniprot id: Q82DE6
names: Similarity
messages: Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family.

227882:SAVERM RS10605
gene id: 227882:SAVERM_RS10605
uniprot id: Q82LJ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan.
messages: Belongs to the glycosyl hydrolase 46 family.
messages: Secreted

227882:SAVERM RS27210
gene id: 227882:SAVERM_RS27210
uniprot id: Q79Z45
names: Similarity
messages: Belongs to the lysine N(6)-hydroxylase/L-ornithine N(5)-oxygenase family.

227882:SAVERM RS04405
gene id: 227882:SAVERM_RS04405
uniprot id: Q82PT3
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

227882:SAVERM RS00675
gene id: 227882:SAVERM_RS00675
uniprot id: Q82RU6
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.

227882:SAVERM RS20115
gene id: 227882:SAVERM_RS20115
uniprot id: Q82GK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Membrane

227882:SAVERM RS10660
gene id: 227882:SAVERM_RS10660
uniprot id: Q82LI4
names: Similarity
messages: Belongs to the catalase family.

227882:SAVERM RS24305
gene id: 227882:SAVERM_RS24305
uniprot id: Q82EA6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DisA family.
messages: Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation; upon encountering a lesion, the DisA focus arrests at the damaged site and halts c-di-AMP synthesis.
messages: Homooctamer.
messages: Participates in a DNA-damage check-point that is active prior to asymmetric division when DNA is damaged. DisA forms globular foci that rapidly scan along the chromosomes during sporulation, searching for lesions. When a lesion is present, DisA pauses at the lesion site. This triggers a cellular response that culminates in a temporary block in sporulation initiation.

227882:SAVERM RS25390
gene id: 227882:SAVERM_RS25390
uniprot id: Q82DQ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

227882:SAVERM RS22685
gene id: 227882:SAVERM_RS22685
uniprot id: Q82F74
names: Similarity
messages: Belongs to the peptidase M18 family.

227882:SAVERM RS26625
gene id: 227882:SAVERM_RS26625
uniprot id: Q82D28
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ClpS family.
messages: Binds to the N-terminal domain of the chaperone ClpA.
messages: Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.

227882:SAVERM RS31515
gene id: 227882:SAVERM_RS31515
uniprot id: Q82AD9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane

227882:SAVERM RS29205
gene id: 227882:SAVERM_RS29205
uniprot id: Q82BP3
names: Function
messages: Catalyzes the reduction of sulfite to sulfide, a step in the biosynthesis of sulfur-containing amino acids and cofactors.

227882:SAVERM RS15555
gene id: 227882:SAVERM_RS15555
uniprot id: Q82IY9
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the oxidation of 1-deoxy-11-beta-hydroxypentalenic acid to 1-deoxy-11-oxopentalenic acid in the biosynthesis of neopentalenolactone antibiotic.
messages: S.avermitilis does not produce pentalenolactone itself in vivo but instead a group of new metabolites that are neopentalenolactone derivatives.

227882:SAVERM RS24085
gene id: 227882:SAVERM_RS24085
uniprot id: Q82EF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

227882:SAVERM RS00900
gene id: 227882:SAVERM_RS00900
uniprot id: Q82RQ0
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

227882:SAVERM RS20995
gene id: 227882:SAVERM_RS20995
uniprot id: Q82G23
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.
messages: Cell membrane
messages: Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

227882:SAVERM RS25535
gene id: 227882:SAVERM_RS25535
uniprot id: Q82DM4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

227882:SAVERM RS28175
gene id: 227882:SAVERM_RS28175
uniprot id: Q82C97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Membrane

227882:SAVERM RS20250
gene id: 227882:SAVERM_RS20250
uniprot id: Q82GH3
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A lyase-type mechanism (elimination/hydration) is suggested for the cleavage of the lactyl ether bond of MurNAc 6-phosphate, with the formation of an alpha,beta-unsaturated aldehyde intermediate with (E)-stereochemistry, followed by the syn addition of water to give product.
messages: Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.
messages: Homodimer.
messages: Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate.

227882:SAVERM RS09090
gene id: 227882:SAVERM_RS09090
uniprot id: Q82ME0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

227882:SAVERM RS21965
gene id: 227882:SAVERM_RS21965
uniprot id: Q82FK5
names: Subcellular Location Annotation
messages: Membrane

227882:SAVERM RS35225
gene id: 227882:SAVERM_RS35225
uniprot id: Q827S0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

227882:SAVERM RS35595
gene id: 227882:SAVERM_RS35595
uniprot id: Q827J5
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

227882:SAVERM RS27510
gene id: 227882:SAVERM_RS27510
uniprot id: Q82CL6
names: Function
names: Similarity
messages: Belongs to the RecD family. RecD-like subfamily.
messages: DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity.

227882:SAVERM RS27985
gene id: 227882:SAVERM_RS27985
uniprot id: Q82CC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

227882:SAVERM RS15870
gene id: 227882:SAVERM_RS15870
uniprot id: Q82IS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0182 family.
messages: Cell membrane

227882:SAVERM RS03475
gene id: 227882:SAVERM_RS03475
uniprot id: Q82QB3
names: Function
names: Subcellular Location Annotation
messages: May play a structural or regulatory role in gas vesicle synthesis.
messages: Vesicle
messages: gas vesicle

227882:SAVERM RS14340
gene id: 227882:SAVERM_RS14340
uniprot id: Q82JK2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm

227882:SAVERM RS10650
gene id: 227882:SAVERM_RS10650
uniprot id: Q82LI6
names: Similarity
messages: Belongs to the hyi family.

227882:SAVERM RS18340
gene id: 227882:SAVERM_RS18340
uniprot id: Q82HF9
names: Subcellular Location Annotation
messages: Membrane

227882:SAVERM RS14610
gene id: 227882:SAVERM_RS14610
uniprot id: Q82JE7
names: Similarity
messages: Belongs to the thioredoxin family.

227882:SAVERM RS25435
gene id: 227882:SAVERM_RS25435
uniprot id: Q82DP3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

227882:SAVERM RS36110
gene id: 227882:SAVERM_RS36110
uniprot id: Q826Z7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

227882:SAVERM RS08725
gene id: 227882:SAVERM_RS08725
uniprot id: Q82ML3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

227882:SAVERM RS07105
gene id: 227882:SAVERM_RS07105
uniprot id: Q82NH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

227882:SAVERM RS25700
gene id: 227882:SAVERM_RS25700
uniprot id: Q82DJ4
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

227882:SAVERM RS32485
gene id: 227882:SAVERM_RS32485
uniprot id: Q829U4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

227882:SAVERM RS15345
gene id: 227882:SAVERM_RS15345
uniprot id: Q82J31
names: Subcellular Location Annotation
messages: Membrane

227882:SAVERM RS27795
gene id: 227882:SAVERM_RS27795
uniprot id: Q82CG6
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

227882:SAVERM RS25410
gene id: 227882:SAVERM_RS25410
uniprot id: Q82DP7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

227882:SAVERM RS17840
gene id: 227882:SAVERM_RS17840
uniprot id: Q82HQ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

227882:SAVERM RS31160
gene id: 227882:SAVERM_RS31160
uniprot id: Q82AK9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with subunits II, III and IV to form cytochrome c oxidase.
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Binds 1 copper B ion per subunit.
messages: Binds 2 heme groups per subunit.
messages: Cell membrane
messages: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B (By similarity).

227882:SAVERM RS31700
gene id: 227882:SAVERM_RS31700
uniprot id: Q82AA2
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

227882:SAVERM RS06870
gene id: 227882:SAVERM_RS06870
uniprot id: Q82NM3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

227882:SAVERM RS14810
gene id: 227882:SAVERM_RS14810
uniprot id: Q82JB6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

227882:SAVERM RS09955
gene id: 227882:SAVERM_RS09955
uniprot id: Q82LX2
names: Function
names: Subcellular Location Annotation
messages: May play a structural or regulatory role in gas vesicle synthesis.
messages: Vesicle
messages: gas vesicle

227882:SAVERM RS34355
gene id: 227882:SAVERM_RS34355
uniprot id: Q828I2
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

227882:SAVERM RS28945
gene id: 227882:SAVERM_RS28945
uniprot id: Q82BU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

227882:SAVERM RS22315
gene id: 227882:SAVERM_RS22315
uniprot id: Q82FD7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

227882:SAVERM RS10730
gene id: 227882:SAVERM_RS10730
uniprot id: Q82LH0
names: Subunit
messages: Heterodimer of an alpha and a beta chain.

227882:SAVERM RS27200
gene id: 227882:SAVERM_RS27200
uniprot id: Q82CR9
names: Similarity
messages: Belongs to the IucA/IucC family.

227882:SAVERM RS13895
gene id: 227882:SAVERM_RS13895
uniprot id: Q82JT5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

227882:SAVERM RS10360
gene id: 227882:SAVERM_RS10360
uniprot id: Q82LP4
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

227882:SAVERM RS29140
gene id: 227882:SAVERM_RS29140
uniprot id: Q82BQ6
names: Subcellular Location Annotation
messages: Membrane

227882:SAVERM RS37455
gene id: 227882:SAVERM_RS37455
uniprot id: Q825Z9
names: Subcellular Location Annotation
messages: Membrane

227882:SAVERM RS35105
gene id: 227882:SAVERM_RS35105
uniprot id: Q827U0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PdxS/SNZ family.
messages: Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
messages: In the presence of PdxT, forms a dodecamer of heterodimers.

227882:SAVERM RS13765
gene id: 227882:SAVERM_RS13765
uniprot id: Q82JW0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

227882:SAVERM RS14355
gene id: 227882:SAVERM_RS14355
uniprot id: Q82JJ9
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.

227882:SAVERM RS10960
gene id: 227882:SAVERM_RS10960
uniprot id: Q82LC4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

227882:SAVERM RS35370
gene id: 227882:SAVERM_RS35370
uniprot id: Q827P2
names: Similarity
messages: Belongs to the ribonuclease N1/T1 family.

227882:SAVERM RS10315
gene id: 227882:SAVERM_RS10315
uniprot id: Q82LQ3
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaved by autocatalysis into a large and a small subunit.
messages: This enzyme consists of two polypeptide chains, which are synthesized in precursor form from a single polypeptide.

227882:SAVERM RS18060
gene id: 227882:SAVERM_RS18060
uniprot id: Q82HL3
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20 family.
messages: Binds 2 Zn(2+) ions per subunit.

227882:SAVERM RS37680
gene id: 227882:SAVERM_RS37680
uniprot id: Q79Z09
names: Function
messages: Catalyzes the hydrolysis of the gamma-glutamyl amide bond of hercynyl-gamma-L-glutamyl-L-cysteine sulfoxide to produce hercynylcysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine.

227882:SAVERM RS24310
gene id: 227882:SAVERM_RS24310
uniprot id: Q82EA5
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

227882:SAVERM RS31185
gene id: 227882:SAVERM_RS31185
uniprot id: Q82AK4
names: Caution
names: PTM
names: Subcellular Location Annotation
names: Subunit
messages: Binds 2 heme c groups covalently per subunit.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The cytochrome bc1 complex is composed of a cytochrome b (QcrB), the Rieske iron-sulfur protein (QcrA) and a diheme cytochrome c (QcrC) subunit.

227882:SAVERM RS24820
gene id: 227882:SAVERM_RS24820
uniprot id: Q82E07
names: Similarity
messages: Belongs to the UbiD family.

227882:SAVERM RS27700
gene id: 227882:SAVERM_RS27700
uniprot id: Q82CI4
names: Subunit
messages: Homotetramer.

227882:SAVERM RS31685
gene id: 227882:SAVERM_RS31685
uniprot id: Q82AA6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

227882:SAVERM RS11790
gene id: 227882:SAVERM_RS11790
uniprot id: Q82KW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

227882:SAVERM RS22310
gene id: 227882:SAVERM_RS22310
uniprot id: Q82FD8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

227882:SAVERM RS23540
gene id: 227882:SAVERM_RS23540
uniprot id: Q82EQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

227882:SAVERM RS25795
gene id: 227882:SAVERM_RS25795
uniprot id: Q82DH6
names: Similarity
messages: Belongs to the IMPDH/GMPR family.

227882:SAVERM RS38945
gene id: 227882:SAVERM_RS38945
uniprot id: Q82P45
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

227882:SAVERM RS31580
gene id: 227882:SAVERM_RS31580
uniprot id: Q82AC7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

227882:SAVERM RS12000
gene id: 227882:SAVERM_RS12000
uniprot id: Q82KS7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

227882:SAVERM RS33200
gene id: 227882:SAVERM_RS33200
uniprot id: Q829F3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

227882:SAVERM RS34445
gene id: 227882:SAVERM_RS34445
uniprot id: Q828G4
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

227882:SAVERM RS22780
gene id: 227882:SAVERM_RS22780
uniprot id: Q82F56
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M7 family.
messages: Binds 1 Ca(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Secreted

227882:SAVERM RS26665
gene id: 227882:SAVERM_RS26665
uniprot id: Q82D20
names: Subcellular Location Annotation
messages: Membrane

227882:SAVERM RS22280
gene id: 227882:SAVERM_RS22280
uniprot id: Q82FE3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Specifically methylates the N7 position of guanine in position 518 of 16S rRNA.

227882:SAVERM RS22400
gene id: 227882:SAVERM_RS22400
uniprot id: Q82FC4
names: Similarity
messages: Belongs to the UPF0749 family.

227882:SAVERM RS02565
gene id: 227882:SAVERM_RS02565
uniprot id: Q82QT6
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

227882:SAVERM RS05905
gene id: 227882:SAVERM_RS05905
uniprot id: Q82P51
names: Similarity
messages: Belongs to the glycosyl hydrolase.

227882:SAVERM RS21685
gene id: 227882:SAVERM_RS21685
uniprot id: Q82FQ8
names: Subcellular Location Annotation
messages: Membrane

227882:SAVERM RS04655
gene id: 227882:SAVERM_RS04655
uniprot id: Q79ZR0
names: Similarity
messages: Belongs to the thioesterase family.

227882:SAVERM RS25485
gene id: 227882:SAVERM_RS25485
uniprot id: Q82DN3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

227882:SAVERM RS26455
gene id: 227882:SAVERM_RS26455
uniprot id: Q82D56
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

227882:SAVERM RS37420
gene id: 227882:SAVERM_RS37420
uniprot id: Q826A6
names: Subcellular Location Annotation
messages: Membrane

227882:SAVERM RS35290
gene id: 227882:SAVERM_RS35290
uniprot id: Q827Q8
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

227882:SAVERM RS21875
gene id: 227882:SAVERM_RS21875
uniprot id: Q82FM2
names: Similarity
messages: Belongs to the peptidase M24B family.

227882:SAVERM RS34730
gene id: 227882:SAVERM_RS34730
uniprot id: Q828A6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

227882:SAVERM RS32025
gene id: 227882:SAVERM_RS32025
uniprot id: Q82A37
names: Subcellular Location Annotation
messages: Membrane

227882:SAVERM RS14680
gene id: 227882:SAVERM_RS14680
uniprot id: Q82JD3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

227882:SAVERM RS06095
gene id: 227882:SAVERM_RS06095
uniprot id: Q82P12
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

227882:SAVERM RS34330
gene id: 227882:SAVERM_RS34330
uniprot id: Q828I7
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
messages: Cytoplasm
messages: The 20S proteasome core is composed of 14 alpha and 14 beta subunits that assemble into four stacked heptameric rings, resulting in a barrel-shaped structure. The two inner rings, each composed of seven catalytic beta subunits, are sandwiched by two outer rings, each composed of seven alpha subunits. The catalytic chamber with the active sites is on the inside of the barrel. Has a gated structure, the ends of the cylinder being occluded by the N-termini of the alpha-subunits. Is capped by the proteasome-associated ATPase, ARC.
messages: The formation of the proteasomal ATPase ARC-20S proteasome complex, likely via the docking of the C-termini of ARC into the intersubunit pockets in the alpha-rings, may trigger opening of the gate for substrate entry. Interconversion between the open-gate and close-gate conformations leads to a dynamic regulation of the 20S proteasome proteolysis activity.

227882:SAVERM RS35205
gene id: 227882:SAVERM_RS35205
uniprot id: Q827S4
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

227882:SAVERM RS14990
gene id: 227882:SAVERM_RS14990
uniprot id: Q82J80
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.

227882:SAVERM RS37270
gene id: 227882:SAVERM_RS37270
uniprot id: Q826D7
names: Similarity
messages: Belongs to the long-chain O-acyltransferase family.

227882:SAVERM RS19870
gene id: 227882:SAVERM_RS19870
uniprot id: Q82GQ1
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

227882:SAVERM RS15795
gene id: 227882:SAVERM_RS15795
uniprot id: Q82IU1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Monomer.

227882:SAVERM RS14970
gene id: 227882:SAVERM_RS14970
uniprot id: Q82J84
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

227882:SAVERM RS10505
gene id: 227882:SAVERM_RS10505
uniprot id: Q82LL5
names: Similarity
messages: Belongs to the allantoicase family.

227882:SAVERM RS27580
gene id: 227882:SAVERM_RS27580
uniprot id: Q82CK2
names: Subcellular Location Annotation
messages: Membrane

227882:SAVERM RS34775
gene id: 227882:SAVERM_RS34775
uniprot id: Q827Z7
names: Subcellular Location Annotation
messages: Membrane

227882:SAVERM RS13070
gene id: 227882:SAVERM_RS13070
uniprot id: Q82K95
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
messages: Cytoplasm

227882:SAVERM RS34745
gene id: 227882:SAVERM_RS34745
uniprot id: Q828A3
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

227882:SAVERM RS25995
gene id: 227882:SAVERM_RS25995
uniprot id: Q82DE1
names: Similarity
messages: Belongs to the cysteine dioxygenase family.

227882:SAVERM RS37665
gene id: 227882:SAVERM_RS37665
uniprot id: Q825V7
names: Subcellular Location Annotation
messages: Membrane

227882:SAVERM RS14690
gene id: 227882:SAVERM_RS14690
uniprot id: Q82JD1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

227882:SAVERM RS01370
gene id: 227882:SAVERM_RS01370
uniprot id: Q82RF6
names: Subcellular Location Annotation
messages: Membrane

227882:SAVERM RS13140
gene id: 227882:SAVERM_RS13140
uniprot id: Q82K86
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidylate synthase ThyX family.
messages: Binds 4 FAD per tetramer. Each FAD binding site is formed by three monomers.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
messages: Homotetramer.

227882:SAVERM RS23450
gene id: 227882:SAVERM_RS23450
uniprot id: Q82ES4
names: Similarity
messages: Belongs to the cytochrome P450 family.

227882:SAVERM RS14450
gene id: 227882:SAVERM_RS14450
uniprot id: Q82JH9
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

227882:SAVERM RS25025
gene id: 227882:SAVERM_RS25025
uniprot id: Q82DW8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

227882:SAVERM RS33050
gene id: 227882:SAVERM_RS33050
uniprot id: Q829I3
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

227882:SAVERM RS07300
gene id: 227882:SAVERM_RS07300
uniprot id: Q82ND6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

227882:SAVERM RS37730
gene id: 227882:SAVERM_RS37730
uniprot id: Q825V0
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

227882:SAVERM RS11175
gene id: 227882:SAVERM_RS11175
uniprot id: Q82L84
names: Function
messages: Catalyzes the reduction of sulfite to sulfide, a step in the biosynthesis of sulfur-containing amino acids and cofactors.

227882:SAVERM RS35700
gene id: 227882:SAVERM_RS35700
uniprot id: Q827H4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MSOX/MTOX family. MSOX subfamily.
messages: Binds 1 FAD per subunit.
messages: Catalyzes the oxidative demethylation of sarcosine.
messages: Cytoplasm
messages: Monomer.

227882:SAVERM RS32995
gene id: 227882:SAVERM_RS32995
uniprot id: Q829J4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobD/CbiB family.
messages: Cell membrane
messages: Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
messages: Membrane

227882:SAVERM RS08000
gene id: 227882:SAVERM_RS08000
uniprot id: Q82MZ6
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

227882:SAVERM RS11590
gene id: 227882:SAVERM_RS11590
uniprot id: Q82L02
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Catalyzes the reversible hydration of carbon dioxide to form bicarbonate.
messages: Reversible hydration of carbon dioxide.

227882:SAVERM RS16195
gene id: 227882:SAVERM_RS16195
uniprot id: Q82IK9
names: Similarity
messages: Belongs to the LOG family.

227882:SAVERM RS22595
gene id: 227882:SAVERM_RS22595
uniprot id: Q82F90
names: Similarity
names: Subunit
messages: Belongs to the Bpa family.
messages: Forms a homooligomeric, either hexameric or heptameric, ring-like structure which stacks co-axially with the proteasomal alpha-rings.

227882:SAVERM RS12550
gene id: 227882:SAVERM_RS12550
uniprot id: Q82KJ9
names: Subcellular Location Annotation
messages: Cell membrane

227882:SAVERM RS09510
gene id: 227882:SAVERM_RS09510
uniprot id: Q82M57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

227882:SAVERM RS14545
gene id: 227882:SAVERM_RS14545
uniprot id: Q82JG0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M4 family.
messages: Extracellular zinc metalloprotease.
messages: Secreted

227882:SAVERM RS11020
gene id: 227882:SAVERM_RS11020
uniprot id: Q81ZY7
names: Similarity
messages: Belongs to the glycosyl hydrolase 10 (cellulase F) family.

227882:SAVERM RS24035
gene id: 227882:SAVERM_RS24035
uniprot id: Q82EG0
names: Similarity
messages: Belongs to the group II decarboxylase family.

227882:SAVERM RS23380
gene id: 227882:SAVERM_RS23380
uniprot id: Q82ET7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tryptophan 2,3-dioxygenase family.
messages: Binds 1 heme group per subunit.
messages: Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L-tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

227882:SAVERM RS35135
gene id: 227882:SAVERM_RS35135
uniprot id: Q827T8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

227882:SAVERM RS26920
gene id: 227882:SAVERM_RS26920
uniprot id: Q82CX1
names: Similarity
messages: Belongs to the glycosyl hydrolase family 6.

227882:SAVERM RS34735
gene id: 227882:SAVERM_RS34735
uniprot id: Q828A5
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e. capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

227882:SAVERM RS17430
gene id: 227882:SAVERM_RS17430
uniprot id: Q82HY8
names: Similarity
messages: Belongs to the BMP lipoprotein family.

227882:SAVERM RS05795
gene id: 227882:SAVERM_RS05795
uniprot id: Q82P73
names: Subcellular Location Annotation
messages: Membrane

227882:SAVERM RS14195
gene id: 227882:SAVERM_RS14195
uniprot id: Q82JN0
names: Cofactor
messages: Binds 1 FAD per subunit.

227882:SAVERM RS20290
gene id: 227882:SAVERM_RS20290
uniprot id: Q82GG5
names: Subcellular Location Annotation
messages: Cytoplasm

227882:SAVERM RS17020
gene id: 227882:SAVERM_RS17020
uniprot id: Q82I70
names: Subcellular Location Annotation
messages: Membrane

227882:SAVERM RS30575
gene id: 227882:SAVERM_RS30575
uniprot id: Q82AX4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

227882:SAVERM RS02570
gene id: 227882:SAVERM_RS02570
uniprot id: Q79ZT5
names: Similarity
messages: Belongs to the cytochrome P450 family.

227882:SAVERM RS25545
gene id: 227882:SAVERM_RS25545
uniprot id: P66302
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

227882:SAVERM RS31695
gene id: 227882:SAVERM_RS31695
uniprot id: Q82AA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

227882:SAVERM RS30990
gene id: 227882:SAVERM_RS30990
uniprot id: Q82AP3
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

227882:SAVERM RS06745
gene id: 227882:SAVERM_RS06745
uniprot id: Q82NP6
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

227882:SAVERM RS35480
gene id: 227882:SAVERM_RS35480
uniprot id: Q827L9
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

227882:SAVERM RS24290
gene id: 227882:SAVERM_RS24290
uniprot id: Q82EA9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sigma-70 factor family. ECF subfamily.
messages: Cytoplasm
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is required for normal cell wall integrity; it is recruited by RNA polymerase to transcribe genes with cell wall-related functions (By similarity).

227882:SAVERM RS10030
gene id: 227882:SAVERM_RS10030
uniprot id: Q82LV7
names: Subcellular Location Annotation
messages: Membrane

227882:SAVERM RS10070
gene id: 227882:SAVERM_RS10070
uniprot id: Q82LU9
names: Activity Regulation
names: Function
names: Similarity
names: Subunit
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Crotonyl-CoA carboxylase/reductase subfamily.
messages: Catalyzes the conversion of crotonyl-CoA to butyryl-CoA. It uses only NADP as electron donor. May have a role in providing butyryl-CoA as a starter unit for straight-chain fatty acid biosynthesis.
messages: Homodimer.
messages: Inhibited by NADPH at concentrations above 200 uM, by MgCl (30%), by ZnCl(2) (55%), and by CoCl, MnCl and CaCl (100%). Also inhibited by iodoacetamide, N-ethylmaleamide, the thiol group inhibitor beta-chloromercuribenzoate, palmitoyl-CoA and myristoyl-CoA.

227882:SAVERM RS15750
gene id: 227882:SAVERM_RS15750
uniprot id: Q82IV0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

227882:SAVERM RS27810
gene id: 227882:SAVERM_RS27810
uniprot id: Q82CG3
names: Subcellular Location Annotation
messages: Membrane

227882:SAVERM RS20940
gene id: 227882:SAVERM_RS20940
uniprot id: Q82G34
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

227882:SAVERM RS12865
gene id: 227882:SAVERM_RS12865
uniprot id: Q82KD6
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

227882:SAVERM RS33285
gene id: 227882:SAVERM_RS33285
uniprot id: Q829D5
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxygen, probably at the conserved histidine residue, and transfers its phosphate group probably to a conserved aspartate residue of NreC. NreB/NreC activates the expression of the nitrate (narGHJI) and nitrite (nir) reductase operons, as well as the putative nitrate transporter gene narT.

227882:SAVERM RS17480
gene id: 227882:SAVERM_RS17480
uniprot id: Q82HX8
names: Function
messages: TetR is the repressor of the tetracycline resistance element; its N-terminal region forms a helix-turn-helix structure and binds DNA. Binding of tetracycline to TetR reduces the repressor affinity for the tetracycline resistance gene (tetA) promoter operator sites.

227882:SAVERM RS10740
gene id: 227882:SAVERM_RS10740
uniprot id: Q82LG8
names: Similarity
messages: Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family.

227882:SAVERM RS13165
gene id: 227882:SAVERM_RS13165
uniprot id: Q82K81
names: Similarity
messages: Belongs to the peptidase M16 family.

227882:SAVERM RS11370
gene id: 227882:SAVERM_RS11370
uniprot id: Q82L46
names: Similarity
messages: Belongs to the damage-control phosphatase family. Sugar phosphate phosphatase III subfamily.

227882:SAVERM RS15800
gene id: 227882:SAVERM_RS15800
uniprot id: Q82IU0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

227882:SAVERM RS14755
gene id: 227882:SAVERM_RS14755
uniprot id: Q79ZD7
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

227882:SAVERM RS38065
gene id: 227882:SAVERM_RS38065
uniprot id: Q825P1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Ribose importer (TC 3.A.1.2.1) family.
messages: Cell membrane
messages: Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system.
messages: The complex is composed of an ATP-binding protein (RbsA), two transmembrane proteins (RbsC) and a solute-binding protein (RbsB).

227882:SAVERM RS22525
gene id: 227882:SAVERM_RS22525
uniprot id: Q82FA3
names: Subcellular Location Annotation
messages: Membrane

227882:SAVERM RS25020
gene id: 227882:SAVERM_RS25020
uniprot id: Q82DW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

227882:SAVERM RS25890
gene id: 227882:SAVERM_RS25890
uniprot id: Q82DG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

227882:SAVERM RS33280
gene id: 227882:SAVERM_RS33280
uniprot id: Q829D6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

227882:SAVERM RS38440
gene id: 227882:SAVERM_RS38440
uniprot id: Q825H1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the protease inhibitor I16 (SSI) family.
messages: Homodimer.
messages: Secreted
messages: Strong inhibitor of bacterial serine proteases such as subtilisin.

227882:SAVERM RS00815
gene id: 227882:SAVERM_RS00815
uniprot id: Q82RR7
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the terpene synthase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Catalyzes the cyclization of farnesyl diphosphate to avermitilol.
messages: The recombinent enzyme produces avermitilol (85%), accompanied by small quantities of germacrene A, germacrene B and viridiflorol.

227882:SAVERM RS06505
gene id: 227882:SAVERM_RS06505
uniprot id: Q82NT5
names: Similarity
messages: Belongs to the DszC flavin monooxygenase family.

227882:SAVERM RS09035
gene id: 227882:SAVERM_RS09035
uniprot id: Q82MF1
names: Function
names: Similarity
messages: Belongs to the anhydro-N-acetylmuramic acid kinase family.
messages: Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.

227882:SAVERM RS07380
gene id: 227882:SAVERM_RS07380
uniprot id: Q82NB9
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

227882:SAVERM RS23575
gene id: 227882:SAVERM_RS23575
uniprot id: Q82EQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SURF1 family.
messages: Cell membrane

227882:SAVERM RS34620
gene id: 227882:SAVERM_RS34620
uniprot id: Q828C8
names: Subcellular Location Annotation
messages: Cell membrane

227882:SAVERM RS31790
gene id: 227882:SAVERM_RS31790
uniprot id: Q82A84
names: Similarity
messages: Belongs to the TrpC family.

227882:SAVERM RS00935
gene id: 227882:SAVERM_RS00935
uniprot id: Q82RP3
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

227882:SAVERM RS38215
gene id: 227882:SAVERM_RS38215
uniprot id: Q825L2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

227882:SAVERM RS04320
gene id: 227882:SAVERM_RS04320
uniprot id: Q82PV1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

227882:SAVERM RS08885
gene id: 227882:SAVERM_RS08885
uniprot id: Q82MI1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

227882:SAVERM RS11195
gene id: 227882:SAVERM_RS11195
uniprot id: Q81ZI7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PAPS reductase family. CysD subfamily.
messages: Heterodimer composed of CysD, the smaller subunit, and CysN.
messages: With CysN forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.

227882:SAVERM RS25560
gene id: 227882:SAVERM_RS25560
uniprot id: P60313
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

227882:SAVERM RS33445
gene id: 227882:SAVERM_RS33445
uniprot id: Q829A7
names: Activity Regulation
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.

227882:SAVERM RS22440
gene id: 227882:SAVERM_RS22440
uniprot id: Q820G2
names: Subcellular Location Annotation
messages: Membrane

227882:SAVERM RS13665
gene id: 227882:SAVERM_RS13665
uniprot id: Q82JY0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

227882:SAVERM RS35140
gene id: 227882:SAVERM_RS35140
uniprot id: Q827T7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

227882:SAVERM RS18135
gene id: 227882:SAVERM_RS18135
uniprot id: Q82HJ8
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

227882:SAVERM RS25745
gene id: 227882:SAVERM_RS25745
uniprot id: Q820G1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

227882:SAVERM RS18480
gene id: 227882:SAVERM_RS18480
uniprot id: Q82HD2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

227882:SAVERM RS28775
gene id: 227882:SAVERM_RS28775
uniprot id: Q82BX8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase Z family.
messages: Binds 2 Zn(2+) ions.
messages: Homodimer.
messages: Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.

227882:SAVERM RS16625
gene id: 227882:SAVERM_RS16625
uniprot id: Q82IE8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

227882:SAVERM RS33005
gene id: 227882:SAVERM_RS33005
uniprot id: Q829J2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane

227882:SAVERM RS24880
gene id: 227882:SAVERM_RS24880
uniprot id: Q82DZ5
names: Function
names: Similarity
messages: Belongs to the MqnA/MqnD family. MqnA subfamily.
messages: Catalyzes the dehydration of chorismate into 3-[(1-carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2).

227882:SAVERM RS06585
gene id: 227882:SAVERM_RS06585
uniprot id: Q82NR8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycosyl hydrolase 2 family.
messages: Hydrolyzes chitosan and chitooligosaccharides with retention of anomeric configuration. Has no beta-mannosidase activity.
messages: Monomer.
messages: Secreted

227882:SAVERM RS38070
gene id: 227882:SAVERM_RS38070
uniprot id: Q825P0
names: Subcellular Location Annotation
messages: Membrane

227882:SAVERM RS13750
gene id: 227882:SAVERM_RS13750
uniprot id: Q82JW3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

227882:SAVERM RS13735
gene id: 227882:SAVERM_RS13735
uniprot id: Q82JW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

227882:SAVERM RS24715
gene id: 227882:SAVERM_RS24715
uniprot id: Q82E29
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

227882:SAVERM RS21935
gene id: 227882:SAVERM_RS21935
uniprot id: Q82FL0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the DyP-type peroxidase family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group non-covalently per subunit.
messages: Involved in the recovery of exogenous heme iron. Extracts iron from heme while preserving the protoporphyrin ring intact.

227882:SAVERM RS36615
gene id: 227882:SAVERM_RS36615
uniprot id: Q79Z27
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

227882:SAVERM RS38935
gene id: 227882:SAVERM_RS38935
uniprot id: Q82PY3
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

227882:SAVERM RS13495
gene id: 227882:SAVERM_RS13495
uniprot id: Q82K14
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
messages: Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD).

227882:SAVERM RS09605
gene id: 227882:SAVERM_RS09605
uniprot id: Q82M40
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CoA-transferase III family. Frc subfamily.
messages: Homodimer.
messages: Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate (By similarity).

227882:SAVERM RS29130
gene id: 227882:SAVERM_RS29130
uniprot id: Q82BQ8
names: Subcellular Location Annotation
messages: Membrane

227882:SAVERM RS33485
gene id: 227882:SAVERM_RS33485
uniprot id: Q828Z9
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

227882:SAVERM RS18830
gene id: 227882:SAVERM_RS18830
uniprot id: Q79Z71
names: Similarity
names: Subunit
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family. SbnA subfamily.
messages: Homodimer.

227882:SAVERM RS13035
gene id: 227882:SAVERM_RS13035
uniprot id: Q82KA2
names: Similarity
messages: Belongs to the FPG family.

227882:SAVERM RS13775
gene id: 227882:SAVERM_RS13775
uniprot id: Q82JV8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
messages: Consists of three domains: the N-terminal catalytic domain, the anticodon-binding domain and the C-terminal extension.
messages: Cytoplasm
messages: Homodimer.

227882:SAVERM RS32665
gene id: 227882:SAVERM_RS32665
uniprot id: Q829Q8
names: Subcellular Location Annotation
messages: Membrane

227882:SAVERM RS37675
gene id: 227882:SAVERM_RS37675
uniprot id: Q79Z10
names: Function
names: Similarity
names: Subunit
messages: Belongs to the methyltransferase superfamily. EgtD family.
messages: Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine.
messages: Monomer.

227882:SAVERM RS36505
gene id: 227882:SAVERM_RS36505
uniprot id: Q826R9
names: Cofactor
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
messages: Binds 2 nickel ions per subunit.
messages: Carboxylation allows a single lysine to coordinate two nickel ions.
messages: Cytoplasm
messages: May form a heterohexamer of 3 UreC (alpha) and 3 UreAB (gamma/beta) subunits. May also form a heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

227882:SAVERM RS20340
gene id: 227882:SAVERM_RS20340
uniprot id: Q82GF5
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

227882:SAVERM RS09285
gene id: 227882:SAVERM_RS09285
uniprot id: Q82MA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

227882:SAVERM RS30050
gene id: 227882:SAVERM_RS30050
uniprot id: Q82B77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GDT1 family.
messages: Membrane

227882:SAVERM RS12270
gene id: 227882:SAVERM_RS12270
uniprot id: Q82KM6
names: Function
names: Subcellular Location Annotation
messages: May play a structural or regulatory role in gas vesicle synthesis.
messages: Vesicle
messages: gas vesicle

227882:SAVERM RS09335
gene id: 227882:SAVERM_RS09335
uniprot id: Q82M92
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

227882:SAVERM RS15140
gene id: 227882:SAVERM_RS15140
uniprot id: Q82J67
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

227882:SAVERM RS32420
gene id: 227882:SAVERM_RS32420
uniprot id: Q829V7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

227882:SAVERM RS09720
gene id: 227882:SAVERM_RS09720
uniprot id: Q82M18
names: Similarity
messages: Belongs to the glycosyl hydrolase 33 family.

227882:SAVERM RS10230
gene id: 227882:SAVERM_RS10230
uniprot id: Q82LR9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. FDH subfamily.
messages: Catalyzes the NAD(+)-dependent oxidation of formate to carbon dioxide. Formate oxidation is the final step in the methanol oxidation pathway in methylotrophic microorganisms. Has a role in the detoxification of exogenous formate in non-methylotrophic organisms.
messages: Cytoplasm
messages: Homodimer.

227882:SAVERM RS34215
gene id: 227882:SAVERM_RS34215
uniprot id: Q828L0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the aldolase class II family. MtnB subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P).

227882:SAVERM RS03835
gene id: 227882:SAVERM_RS03835
uniprot id: Q82Q56
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

227882:SAVERM RS21250
gene id: 227882:SAVERM_RS21250
uniprot id: Q82FY3
names: Function
names: Similarity
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

227882:SAVERM RS25495
gene id: 227882:SAVERM_RS25495
uniprot id: Q82DN2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

227882:SAVERM RS10485
gene id: 227882:SAVERM_RS10485
uniprot id: Q82LL9
names: Similarity
messages: Belongs to the ribonuclease N1/T1 family.

227882:SAVERM RS30805
gene id: 227882:SAVERM_RS30805
uniprot id: Q82AS9
names: Similarity
messages: Belongs to the bacterial solute-binding protein 1 family.

227882:SAVERM RS36440
gene id: 227882:SAVERM_RS36440
uniprot id: Q826T2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

227882:SAVERM RS33850
gene id: 227882:SAVERM_RS33850
uniprot id: Q828S5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the homogentisate dioxygenase family.
messages: Hexamer; dimer of trimers.
messages: Involved in the catabolism of homogentisate (2,5-dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate.

227882:SAVERM RS33120
gene id: 227882:SAVERM_RS33120
uniprot id: Q829G9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

227882:SAVERM RS33460
gene id: 227882:SAVERM_RS33460
uniprot id: Q829A4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AlaDH/PNT family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reductive amination of pyruvate to L-alanine.

227882:SAVERM RS24930
gene id: 227882:SAVERM_RS24930
uniprot id: Q81ZX2
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).

227882:SAVERM RS33560
gene id: 227882:SAVERM_RS33560
uniprot id: Q828Y4
names: Similarity
messages: Belongs to the transglycosylase family. Rpf subfamily.

227882:SAVERM RS22385
gene id: 227882:SAVERM_RS22385
uniprot id: Q82FC6
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

227882:SAVERM RS31885
gene id: 227882:SAVERM_RS31885
uniprot id: Q82A64
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

227882:SAVERM RS33225
gene id: 227882:SAVERM_RS33225
uniprot id: Q829E8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

227882:SAVERM RS37825
gene id: 227882:SAVERM_RS37825
uniprot id: Q79Z00
names: Similarity
names: Subunit
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase small subunit family.
messages: Heterodimer of a large and a small subunit.

227882:SAVERM RS37015
gene id: 227882:SAVERM_RS37015
uniprot id: Q826I8
names: Function
messages: Catalyzes the phosphorylation of hydroxymethylpyrimidine phosphate (HMP-P) to HMP-PP, and of HMP to HMP-P.

227882:SAVERM RS31715
gene id: 227882:SAVERM_RS31715
uniprot id: Q82A99
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

227882:SAVERM RS11905
gene id: 227882:SAVERM_RS11905
uniprot id: Q79ZI0
names: Subcellular Location Annotation
messages: Membrane

227882:SAVERM RS01065
gene id: 227882:SAVERM_RS01065
uniprot id: Q82RL4
names: Subcellular Location Annotation
messages: Cell membrane

227882:SAVERM RS35435
gene id: 227882:SAVERM_RS35435
uniprot id: Q827M8
names: Similarity
messages: Belongs to the glycosyl hydrolase family 6.

227882:SAVERM RS06845
gene id: 227882:SAVERM_RS06845
uniprot id: Q82NM8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.
messages: Homotetramer.
messages: Uses inorganic polyphosphate (polyP) as a donor to convert GDP to GTP or ADP to ATP.

227882:SAVERM RS13320
gene id: 227882:SAVERM_RS13320
uniprot id: Q82K51
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

227882:SAVERM RS22095
gene id: 227882:SAVERM_RS22095
uniprot id: Q82FH9
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

227882:SAVERM RS26260
gene id: 227882:SAVERM_RS26260
uniprot id: Q82D91
names: Similarity
messages: Belongs to the OsmC/Ohr family.

227882:SAVERM RS24150
gene id: 227882:SAVERM_RS24150
uniprot id: Q82ED7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

227882:SAVERM RS35850
gene id: 227882:SAVERM_RS35850
uniprot id: Q827E8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

227882:SAVERM RS27230
gene id: 227882:SAVERM_RS27230
uniprot id: Q79Z42
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

227882:SAVERM RS31980
gene id: 227882:SAVERM_RS31980
uniprot id: Q82A45
names: Similarity
messages: Belongs to the lysine N(6)-hydroxylase/L-ornithine N(5)-oxygenase family.

227882:SAVERM RS06135
gene id: 227882:SAVERM_RS06135
uniprot id: Q82P04
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

227882:SAVERM RS14580
gene id: 227882:SAVERM_RS14580
uniprot id: Q82JF3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgE subfamily.
messages: Homodimer.
messages: Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1->4)-glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB.

227882:SAVERM RS30470
gene id: 227882:SAVERM_RS30470
uniprot id: Q82AZ6
names: Subcellular Location Annotation
messages: Membrane

227882:SAVERM RS09745
gene id: 227882:SAVERM_RS09745
uniprot id: Q82M13
names: Subcellular Location Annotation
messages: Membrane

227882:SAVERM RS28990
gene id: 227882:SAVERM_RS28990
uniprot id: Q82BT6
names: Similarity
messages: Belongs to the clavaminate synthase family.

227882:SAVERM RS26275
gene id: 227882:SAVERM_RS26275
uniprot id: Q82D88
names: Similarity
messages: Belongs to the CDP-glycerol glycerophosphotransferase family.

227882:SAVERM RS16650
gene id: 227882:SAVERM_RS16650
uniprot id: Q82IE3
names: Similarity
messages: Belongs to the FBPase class 2 family.

227882:SAVERM RS28905
gene id: 227882:SAVERM_RS28905
uniprot id: Q82BV3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homotetramer.

227882:SAVERM RS38220
gene id: 227882:SAVERM_RS38220
uniprot id: Q825L1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

227882:SAVERM RS15340
gene id: 227882:SAVERM_RS15340
uniprot id: Q82J32
names: Subcellular Location Annotation
messages: Cell membrane

227882:SAVERM RS32160
gene id: 227882:SAVERM_RS32160
uniprot id: Q82A10
names: Similarity
messages: Belongs to the cytochrome P450 family.

227882:SAVERM RS29075
gene id: 227882:SAVERM_RS29075
uniprot id: Q82BR9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of glycine to tRNA(Gly).
messages: Cytoplasm
messages: Homodimer.

227882:SAVERM RS20360
gene id: 227882:SAVERM_RS20360
uniprot id: Q82GF1
names: Similarity
messages: Belongs to the prokaryotic/mitochondrial release factor family.

227882:SAVERM RS34385
gene id: 227882:SAVERM_RS34385
uniprot id: Q828H6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

227882:SAVERM RS26905
gene id: 227882:SAVERM_RS26905
uniprot id: Q82CX4
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

227882:SAVERM RS32745
gene id: 227882:SAVERM_RS32745
uniprot id: Q829P2
names: Similarity
messages: Belongs to the IlvD/Edd family.

227882:SAVERM RS32455
gene id: 227882:SAVERM_RS32455
uniprot id: Q829V0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

227882:SAVERM RS35320
gene id: 227882:SAVERM_RS35320
uniprot id: Q827Q2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

227882:SAVERM RS11975
gene id: 227882:SAVERM_RS11975
uniprot id: Q82KT2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

227882:SAVERM RS15685
gene id: 227882:SAVERM_RS15685
uniprot id: Q82IW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

227882:SAVERM RS36100
gene id: 227882:SAVERM_RS36100
uniprot id: Q826Z9
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

227882:SAVERM RS12765
gene id: 227882:SAVERM_RS12765
uniprot id: Q82KF6
names: Similarity
messages: Belongs to the Nudix hydrolase family.

227882:SAVERM RS22305
gene id: 227882:SAVERM_RS22305
uniprot id: Q82FD9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

227882:SAVERM RS31655
gene id: 227882:SAVERM_RS31655
uniprot id: Q82AB2
names: Subcellular Location Annotation
messages: Membrane

227882:SAVERM RS34545
gene id: 227882:SAVERM_RS34545
uniprot id: Q828E4
names: Similarity
messages: Belongs to the glutamine synthetase family.

227882:SAVERM RS06970
gene id: 227882:SAVERM_RS06970
uniprot id: Q82NK3
names: Similarity
messages: Belongs to the universal stress protein A family.

227882:SAVERM RS11245
gene id: 227882:SAVERM_RS11245
uniprot id: Q82L70
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

227882:SAVERM RS04750
gene id: 227882:SAVERM_RS04750
uniprot id: Q79ZP4
names: Similarity
messages: Belongs to the thioesterase family.

227882:SAVERM RS34480
gene id: 227882:SAVERM_RS34480
uniprot id: Q828F7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

227882:SAVERM RS35490
gene id: 227882:SAVERM_RS35490
uniprot id: Q827L7
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Feedback inhibited by histidine.

227882:SAVERM RS29435
gene id: 227882:SAVERM_RS29435
uniprot id: Q82BK0
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

227882:SAVERM RS13485
gene id: 227882:SAVERM_RS13485
uniprot id: Q82K16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

227882:SAVERM RS20990
gene id: 227882:SAVERM_RS20990
uniprot id: Q82G24
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

227882:SAVERM RS32825
gene id: 227882:SAVERM_RS32825
uniprot id: Q829M8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polysaccharide lyase 3 family.
messages: Catalyzes the depolymerization of both polygalacturonate and pectins of methyl esterification degree from 22 to 89%, with an endo mode of action. In contrast to the majority of pectate lyases, displays high activity on highly methylated pectins.
messages: Secreted

227882:SAVERM RS07035
gene id: 227882:SAVERM_RS07035
uniprot id: Q82NI9
names: Similarity
names: Subunit
messages: Belongs to the glutaminase family.
messages: Homotetramer.

227882:SAVERM RS05495
gene id: 227882:SAVERM_RS05495
uniprot id: Q82PC3
names: Similarity
messages: Belongs to the peptidase S1 family.

227882:SAVERM RS31335
gene id: 227882:SAVERM_RS31335
uniprot id: Q82AH4
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
messages: Cytoplasm
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Non-allosteric.

227882:SAVERM RS07020
gene id: 227882:SAVERM_RS07020
uniprot id: Q82NJ3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

227882:SAVERM RS36955
gene id: 227882:SAVERM_RS36955
uniprot id: Q826J9
names: Similarity
messages: Belongs to the eukaryotic/archaeal PrmC-related family.

227882:SAVERM RS18695
gene id: 227882:SAVERM_RS18695
uniprot id: Q82H90
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S41B family.
messages: Cytoplasm
messages: Degrades oligopeptides.

227882:SAVERM RS36375
gene id: 227882:SAVERM_RS36375
uniprot id: Q826U5
names: Subcellular Location Annotation
messages: Membrane

227882:SAVERM RS30510
gene id: 227882:SAVERM_RS30510
uniprot id: Q82AY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell membrane
messages: Membrane

227882:SAVERM RS31165
gene id: 227882:SAVERM_RS31165
uniprot id: Q82AK8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with subunits I, II and III to form cytochrome c oxidase.
messages: Belongs to the cytochrome c oxidase bacterial subunit CtaF family.
messages: Cell membrane
messages: Part of cytochrome c oxidase, its function is unknown.

227882:SAVERM RS30270
gene id: 227882:SAVERM_RS30270
uniprot id: Q82B33
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

227882:SAVERM RS05665
gene id: 227882:SAVERM_RS05665
uniprot id: Q82P98
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.

227882:SAVERM RS05605
gene id: 227882:SAVERM_RS05605
uniprot id: Q79ZL0
names: Similarity
messages: Belongs to the carotenoid/retinoid oxidoreductase family.

227882:SAVERM RS09255
gene id: 227882:SAVERM_RS09255
uniprot id: Q82MA7
names: Similarity
messages: Belongs to the glycosyl hydrolase 38 family.

227882:SAVERM RS19735
gene id: 227882:SAVERM_RS19735
uniprot id: Q82GS7
names: Similarity
messages: Belongs to the F420H(2)-dependent quinone reductase family.

227882:SAVERM RS21930
gene id: 227882:SAVERM_RS21930
uniprot id: Q82FL1
names: Subcellular Location Annotation
messages: Membrane

227882:SAVERM RS09115
gene id: 227882:SAVERM_RS09115
uniprot id: Q82MD5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

227882:SAVERM RS23940
gene id: 227882:SAVERM_RS23940
uniprot id: Q82EH9
names: Similarity
messages: Belongs to the DNA polymerase type-A family.

227882:SAVERM RS27215
gene id: 227882:SAVERM_RS27215
uniprot id: Q79Z44
names: Similarity
messages: Belongs to the group II decarboxylase family.

227882:SAVERM RS06545
gene id: 227882:SAVERM_RS06545
uniprot id: Q82NS6
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

227882:SAVERM RS16245
gene id: 227882:SAVERM_RS16245
uniprot id: Q82IJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Membrane

227882:SAVERM RS34695
gene id: 227882:SAVERM_RS34695
uniprot id: Q828B3
names: Similarity
messages: Belongs to the glycosyl hydrolase 51 family.

227882:SAVERM RS25470
gene id: 227882:SAVERM_RS25470
uniprot id: Q82DN6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

227882:SAVERM RS07870
gene id: 227882:SAVERM_RS07870
uniprot id: Q82N22
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta subunit.
messages: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

227882:SAVERM RS14150
gene id: 227882:SAVERM_RS14150
uniprot id: Q82JP0
names: Similarity
messages: Belongs to the agmatine deiminase family.

227882:SAVERM RS12180
gene id: 227882:SAVERM_RS12180
uniprot id: Q82KP3
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.

227882:SAVERM RS28820
gene id: 227882:SAVERM_RS28820
uniprot id: Q82BW9
names: Subcellular Location Annotation
messages: Membrane

227882:SAVERM RS12125
gene id: 227882:SAVERM_RS12125
uniprot id: Q82KQ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm
messages: Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.

227882:SAVERM RS02930
gene id: 227882:SAVERM_RS02930
uniprot id: Q82QL7
names: Function
messages: TetR is the repressor of the tetracycline resistance element; its N-terminal region forms a helix-turn-helix structure and binds DNA. Binding of tetracycline to TetR reduces the repressor affinity for the tetracycline resistance gene (tetA) promoter operator sites.

227882:SAVERM RS30120
gene id: 227882:SAVERM_RS30120
uniprot id: Q82B63
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

227882:SAVERM RS04965
gene id: 227882:SAVERM_RS04965
uniprot id: Q82PK4
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

227882:SAVERM RS17585
gene id: 227882:SAVERM_RS17585
uniprot id: Q82HV9
names: Subcellular Location Annotation
messages: Membrane

227882:SAVERM RS08105
gene id: 227882:SAVERM_RS08105
uniprot id: Q82MX6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

227882:SAVERM RS20090
gene id: 227882:SAVERM_RS20090
uniprot id: Q82GK5
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

227882:SAVERM RS34905
gene id: 227882:SAVERM_RS34905
uniprot id: Q827X1
names: Similarity
messages: Belongs to the Nudix hydrolase family.

227882:SAVERM RS29060
gene id: 227882:SAVERM_RS29060
uniprot id: Q82BS2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

227882:SAVERM RS11865
gene id: 227882:SAVERM_RS11865
uniprot id: Q82KU7
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

227882:SAVERM RS25385
gene id: 227882:SAVERM_RS25385
uniprot id: P0A4A4
names: Biotechnology
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity).
messages: One streptomycin resistant strain of S.coelicolor and S.lividans (K88E) produces increased quantities of the natural antibiotic actinorhodin; strains which are resistant to multiple drugs produce more antibiotic.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex (By similarity).
messages: With S4 and S5 plays an important role in translational accuracy.

227882:SAVERM RS25690
gene id: 227882:SAVERM_RS25690
uniprot id: Q82DJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

227882:SAVERM RS21440
gene id: 227882:SAVERM_RS21440
uniprot id: Q82FV3
names: Similarity
messages: Belongs to the GARS family.

227882:SAVERM RS09690
gene id: 227882:SAVERM_RS09690
uniprot id: Q82M23
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhD family.
messages: Cytoplasm
messages: Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.

227882:SAVERM RS11915
gene id: 227882:SAVERM_RS11915
uniprot id: Q79ZH8
names: Similarity
messages: Belongs to the thioesterase family.

227882:SAVERM RS18065
gene id: 227882:SAVERM_RS18065
uniprot id: Q82HL2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urocanase family.
messages: Binds 1 NAD(+) per subunit.
messages: Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
messages: Cytoplasm

227882:SAVERM RS38460
gene id: 227882:SAVERM_RS38460
uniprot id: Q825G7
names: Subcellular Location Annotation
messages: Membrane

227882:SAVERM RS24375
gene id: 227882:SAVERM_RS24375
uniprot id: Q82E93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

227882:SAVERM RS36785
gene id: 227882:SAVERM_RS36785
uniprot id: Q79Z22
names: Similarity
messages: Belongs to the CdaR family.

227882:SAVERM RS12575
gene id: 227882:SAVERM_RS12575
uniprot id: Q82KJ4
names: Similarity
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.

227882:SAVERM RS31705
gene id: 227882:SAVERM_RS31705
uniprot id: Q82AA1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Involved in both the histidine and tryptophan biosynthetic pathways.

227882:SAVERM RS15805
gene id: 227882:SAVERM_RS15805
uniprot id: Q82IT9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

227882:SAVERM RS27650
gene id: 227882:SAVERM_RS27650
uniprot id: Q82CI9
names: Subcellular Location Annotation
messages: Membrane

227882:SAVERM RS09975
gene id: 227882:SAVERM_RS09975
uniprot id: Q82LW8
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

227882:SAVERM RS04880
gene id: 227882:SAVERM_RS04880
uniprot id: Q82PM1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An FAD-requiring monooxygenase active on some tetracycline antibiotic derivatives, which leads to their inactivation. Hydroxylates carbon 11a of tetracycline and some analogs.
messages: Belongs to the aromatic-ring hydroxylase family. TetX subfamily.
messages: Consists of an N-terminal FAD-binding domain with a Rossman fold and a C-terminal substrate-binding domain.
messages: Cytoplasm
messages: Monomer.

227882:SAVERM RS27380
gene id: 227882:SAVERM_RS27380
uniprot id: Q82CP0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

227882:SAVERM RS17195
gene id: 227882:SAVERM_RS17195
uniprot id: Q82I37
names: Subcellular Location Annotation
messages: Membrane

227882:SAVERM RS14760
gene id: 227882:SAVERM_RS14760
uniprot id: Q79ZD6
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

227882:SAVERM RS36430
gene id: 227882:SAVERM_RS36430
uniprot id: Q826T4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.

227882:SAVERM RS09620
gene id: 227882:SAVERM_RS09620
uniprot id: Q82M37
names: Subcellular Location Annotation
messages: Membrane

227882:SAVERM RS06930
gene id: 227882:SAVERM_RS06930
uniprot id: Q82NL1
names: Similarity
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

227882:SAVERM RS37745
gene id: 227882:SAVERM_RS37745
uniprot id: Q825U7
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

227882:SAVERM RS27730
gene id: 227882:SAVERM_RS27730
uniprot id: Q82CH8
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

227882:SAVERM RS14910
gene id: 227882:SAVERM_RS14910
uniprot id: Q82J96
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

227882:SAVERM RS08805
gene id: 227882:SAVERM_RS08805
uniprot id: Q82MJ7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IPP isomerase type 1 family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium ion binds only when substrate is bound.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).
messages: Cytoplasm

227882:SAVERM RS34310
gene id: 227882:SAVERM_RS34310
uniprot id: Q828J2
names: Domain
names: Function
names: Similarity
names: Subunit
messages: ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis.
messages: Belongs to the AAA ATPase family.
messages: Consists of three main regions, an N-terminal coiled-coil domain that binds to protein Pup and functions as a docking station, an interdomain involved in ARC hexamerization, and a C-terminal ATPase domain of the AAA type.
messages: Homohexamer. Assembles into a hexameric ring structure that caps the 20S proteasome core. Strongly interacts with the prokaryotic ubiquitin-like protein Pup through a hydrophobic interface; the interacting region of ARC lies in its N-terminal coiled-coil domain. There is one Pup binding site per ARC hexamer ring. Upon ATP-binding, the C-terminus of ARC interacts with the alpha-rings of the proteasome core, possibly by binding to the intersubunit pockets.

227882:SAVERM RS35855
gene id: 227882:SAVERM_RS35855
uniprot id: Q827E7
names: Similarity
messages: Belongs to the phosphohexose mutase family.

227882:SAVERM RS07065
gene id: 227882:SAVERM_RS07065
uniprot id: Q82NI3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.

227882:SAVERM RS32660
gene id: 227882:SAVERM_RS32660
uniprot id: Q829Q9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ro 60 kDa family.
messages: Cytoplasm

227882:SAVERM RS12005
gene id: 227882:SAVERM_RS12005
uniprot id: Q82KS6
names: Cofactor
names: Function
messages: Binds 1 [3Fe-4S] cluster.
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

227882:SAVERM RS25050
gene id: 227882:SAVERM_RS25050
uniprot id: Q82DW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

227882:SAVERM RS37180
gene id: 227882:SAVERM_RS37180
uniprot id: Q826F5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

227882:SAVERM RS34235
gene id: 227882:SAVERM_RS34235
uniprot id: Q828K6
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

227882:SAVERM RS27315
gene id: 227882:SAVERM_RS27315
uniprot id: Q82CQ1
names: Subcellular Location Annotation
messages: Secreted

227882:SAVERM RS15135
gene id: 227882:SAVERM_RS15135
uniprot id: Q82J68
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

227882:SAVERM RS12480
gene id: 227882:SAVERM_RS12480
uniprot id: Q82KL3
names: Subcellular Location Annotation
messages: Membrane

227882:SAVERM RS25500
gene id: 227882:SAVERM_RS25500
uniprot id: Q82DN1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

227882:SAVERM RS27235
gene id: 227882:SAVERM_RS27235
uniprot id: Q82CR7
names: Similarity
messages: Belongs to the HMG-CoA lyase family.

227882:SAVERM RS13420
gene id: 227882:SAVERM_RS13420
uniprot id: Q82K31
names: Similarity
messages: Belongs to the glycosyl hydrolase 42 family.

227882:SAVERM RS22705
gene id: 227882:SAVERM_RS22705
uniprot id: Q82F70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

227882:SAVERM RS38530
gene id: 227882:SAVERM_RS38530
uniprot id: Q825F2
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

227882:SAVERM RS11155
gene id: 227882:SAVERM_RS11155
uniprot id: Q82L88
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

227882:SAVERM RS15690
gene id: 227882:SAVERM_RS15690
uniprot id: Q82IW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

227882:SAVERM RS19120
gene id: 227882:SAVERM_RS19120
uniprot id: Q82H40
names: Similarity
messages: Belongs to the acyl-CoA oxidase family.

227882:SAVERM RS27945
gene id: 227882:SAVERM_RS27945
uniprot id: Q82CD7
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

227882:SAVERM RS26060
gene id: 227882:SAVERM_RS26060
uniprot id: Q82DC7
names: Subcellular Location Annotation
messages: Membrane

227882:SAVERM RS11680
gene id: 227882:SAVERM_RS11680
uniprot id: Q82KY4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.

227882:SAVERM RS24980
gene id: 227882:SAVERM_RS24980
uniprot id: Q82DX7
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.

227882:SAVERM RS05340
gene id: 227882:SAVERM_RS05340
uniprot id: Q82PF2
names: Subcellular Location Annotation
messages: Membrane

227882:SAVERM RS14935
gene id: 227882:SAVERM_RS14935
uniprot id: Q82J91
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

227882:SAVERM RS11565
gene id: 227882:SAVERM_RS11565
uniprot id: Q82L07
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

227882:SAVERM RS38420
gene id: 227882:SAVERM_RS38420
uniprot id: Q825H5
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

227882:SAVERM RS34245
gene id: 227882:SAVERM_RS34245
uniprot id: Q828K4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

227882:SAVERM RS23165
gene id: 227882:SAVERM_RS23165
uniprot id: Q82EX8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

227882:SAVERM RS30635
gene id: 227882:SAVERM_RS30635
uniprot id: Q82AW2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

227882:SAVERM RS21590
gene id: 227882:SAVERM_RS21590
uniprot id: Q82FS4
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

227882:SAVERM RS06180
gene id: 227882:SAVERM_RS06180
uniprot id: Q79ZK0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

227882:SAVERM RS24095
gene id: 227882:SAVERM_RS24095
uniprot id: Q82EE8
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Toroid-shaped homodecamer, composed of two pentamers of five dimers.

227882:SAVERM RS09680
gene id: 227882:SAVERM_RS09680
uniprot id: Q82M25
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

227882:SAVERM RS17580
gene id: 227882:SAVERM_RS17580
uniprot id: Q82HW0
names: Cofactor
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.

227882:SAVERM RS17395
gene id: 227882:SAVERM_RS17395
uniprot id: Q82HZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta sliding clamp family.
messages: Cytoplasm

227882:SAVERM RS13190
gene id: 227882:SAVERM_RS13190
uniprot id: Q82K76
names: Similarity
messages: Belongs to the EccD/Snm4 family.

227882:SAVERM RS07075
gene id: 227882:SAVERM_RS07075
uniprot id: Q82NI1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.

227882:SAVERM RS16600
gene id: 227882:SAVERM_RS16600
uniprot id: Q82IF3
names: Similarity
messages: Belongs to the YoeB family.

227882:SAVERM RS04230
gene id: 227882:SAVERM_RS04230
uniprot id: Q82PX1
names: Function
names: Similarity
messages: ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.
messages: Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.

227882:SAVERM RS32980
gene id: 227882:SAVERM_RS32980
uniprot id: Q829J7
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family.

227882:SAVERM RS28285
gene id: 227882:SAVERM_RS28285
uniprot id: Q82C74
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein L14 (rplN).

227882:SAVERM RS20660
gene id: 227882:SAVERM_RS20660
uniprot id: Q82G90
names: Similarity
messages: Belongs to the peptidase C40 family.

227882:SAVERM RS36325
gene id: 227882:SAVERM_RS36325
uniprot id: Q826V5
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

227882:SAVERM RS25510
gene id: 227882:SAVERM_RS25510
uniprot id: Q82DM9
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

227882:SAVERM RS07205
gene id: 227882:SAVERM_RS07205
uniprot id: Q82NF6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

227882:SAVERM RS25235
gene id: 227882:SAVERM_RS25235
uniprot id: Q82DS7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

227882:SAVERM RS33510
gene id: 227882:SAVERM_RS33510
uniprot id: Q828Z4
names: Function
names: Subcellular Location Annotation
messages: Iron-sulfur subunit of the cytochrome bc1 complex, an essential component of the respiratory electron transport chain required for ATP synthesis. The bc1 complex catalyzes the oxidation of menaquinol and the reduction of cytochrome c in the respiratory chain. The bc1 complex operates through a Q-cycle mechanism that couples electron transfer to generation of the proton gradient that drives ATP synthesis.
messages: Membrane

227882:SAVERM RS22170
gene id: 227882:SAVERM_RS22170
uniprot id: Q82FG5
names: Subunit
messages: Homotetramer.

227882:SAVERM RS12890
gene id: 227882:SAVERM_RS12890
uniprot id: Q82KD1
names: Similarity
messages: Belongs to the RelA/SpoT family.

227882:SAVERM RS18915
gene id: 227882:SAVERM_RS18915
uniprot id: Q79Z56
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

227882:SAVERM RS25430
gene id: 227882:SAVERM_RS25430
uniprot id: Q82DP4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

227882:SAVERM RS28160
gene id: 227882:SAVERM_RS28160
uniprot id: Q82CA0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

227882:SAVERM RS30245
gene id: 227882:SAVERM_RS30245
uniprot id: Q82B38
names: Subcellular Location Annotation
messages: Membrane

227882:SAVERM RS32030
gene id: 227882:SAVERM_RS32030
uniprot id: Q82A36
names: Subcellular Location Annotation
messages: Membrane

227882:SAVERM RS31805
gene id: 227882:SAVERM_RS31805
uniprot id: Q82A81
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

227882:SAVERM RS37860
gene id: 227882:SAVERM_RS37860
uniprot id: Q820F2
names: Function
names: Similarity
messages: Belongs to the HypA/HybF family.
messages: Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.

227882:SAVERM RS22660
gene id: 227882:SAVERM_RS22660
uniprot id: Q82F80
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

227882:SAVERM RS17690
gene id: 227882:SAVERM_RS17690
uniprot id: Q82HT9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Belongs to the peptidase S8 family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

227882:SAVERM RS31745
gene id: 227882:SAVERM_RS31745
uniprot id: Q82A93
names: Subcellular Location Annotation
messages: Membrane

227882:SAVERM RS18445
gene id: 227882:SAVERM_RS18445
uniprot id: Q82HD9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. Tam family.
messages: Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate.
messages: Cytoplasm

227882:SAVERM RS16455
gene id: 227882:SAVERM_RS16455
uniprot id: Q82IH0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

227882:SAVERM RS25775
gene id: 227882:SAVERM_RS25775
uniprot id: Q82DI0
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

227882:SAVERM RS22235
gene id: 227882:SAVERM_RS22235
uniprot id: Q82FF2
names: Subcellular Location Annotation
messages: Membrane

227882:SAVERM RS21920
gene id: 227882:SAVERM_RS21920
uniprot id: Q82FL3
names: Similarity
messages: Belongs to the SCO1/2 family.

227882:SAVERM RS35820
gene id: 227882:SAVERM_RS35820
uniprot id: Q827F0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

227882:SAVERM RS35360
gene id: 227882:SAVERM_RS35360
uniprot id: Q827P4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

227882:SAVERM RS03460
gene id: 227882:SAVERM_RS03460
uniprot id: Q82QB7
names: Function
names: Subcellular Location Annotation
messages: May play a structural or regulatory role in gas vesicle synthesis.
messages: Vesicle
messages: gas vesicle

227882:SAVERM RS34030
gene id: 227882:SAVERM_RS34030
uniprot id: Q828N9
names: Subcellular Location Annotation
messages: Membrane

227882:SAVERM RS05285
gene id: 227882:SAVERM_RS05285
uniprot id: Q82PG1
names: Similarity
messages: Belongs to the YciI family.

227882:SAVERM RS35645
gene id: 227882:SAVERM_RS35645
uniprot id: Q827I5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LamB/PxpA family.
messages: Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
messages: Forms a complex composed of PxpA, PxpB and PxpC.

227882:SAVERM RS15035
gene id: 227882:SAVERM_RS15035
uniprot id: Q79ZC5
names: Similarity
messages: Belongs to the cytochrome P450 family.

227882:SAVERM RS27170
gene id: 227882:SAVERM_RS27170
uniprot id: Q82CS5
names: Similarity
messages: Belongs to the universal stress protein A family.

227882:SAVERM RS17225
gene id: 227882:SAVERM_RS17225
uniprot id: Q82I31
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

227882:SAVERM RS31415
gene id: 227882:SAVERM_RS31415
uniprot id: Q82AF9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).

227882:SAVERM RS31200
gene id: 227882:SAVERM_RS31200
uniprot id: Q82AK1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.

227882:SAVERM RS27540
gene id: 227882:SAVERM_RS27540
uniprot id: Q82CL0
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

227882:SAVERM RS03370
gene id: 227882:SAVERM_RS03370
uniprot id: Q82QD5
names: Similarity
messages: In the N-terminal section; belongs to the cytochrome P450 family.

227882:SAVERM RS38230
gene id: 227882:SAVERM_RS38230
uniprot id: Q825K9
names: Subcellular Location Annotation
messages: Membrane

227882:SAVERM RS36050
gene id: 227882:SAVERM_RS36050
uniprot id: Q81ZV4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell membrane
messages: Membrane

227882:SAVERM RS03415
gene id: 227882:SAVERM_RS03415
uniprot id: Q82QC6
names: Similarity
messages: Belongs to the cytochrome P450 family.

227882:SAVERM RS20525
gene id: 227882:SAVERM_RS20525
uniprot id: Q82GB9
names: Subcellular Location Annotation
messages: Membrane

227882:SAVERM RS13465
gene id: 227882:SAVERM_RS13465
uniprot id: Q82K21
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

227882:SAVERM RS18500
gene id: 227882:SAVERM_RS18500
uniprot id: Q82HC8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

227882:SAVERM RS16140
gene id: 227882:SAVERM_RS16140
uniprot id: Q82IM1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.
messages: In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: In the N-terminal section; belongs to the MIP18 family.

227882:SAVERM RS22320
gene id: 227882:SAVERM_RS22320
uniprot id: Q82FD6
names: Similarity
messages: Belongs to the 6-phosphogluconate dehydrogenase family.

227882:SAVERM RS05510
gene id: 227882:SAVERM_RS05510
uniprot id: Q82PC0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

227882:SAVERM RS13845
gene id: 227882:SAVERM_RS13845
uniprot id: Q82JU5
names: Similarity
messages: Belongs to the acylphosphatase family.

227882:SAVERM RS31350
gene id: 227882:SAVERM_RS31350
uniprot id: Q82AH1
names: Similarity
messages: Belongs to the class-II DAHP synthase family.

227882:SAVERM RS24960
gene id: 227882:SAVERM_RS24960
uniprot id: Q82DY1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

227882:SAVERM RS17640
gene id: 227882:SAVERM_RS17640
uniprot id: Q82HU8
names: Subcellular Location Annotation
messages: Cell membrane

227882:SAVERM RS09065
gene id: 227882:SAVERM_RS09065
uniprot id: Q82ME5
names: Similarity
messages: Belongs to the bacterial phospholipase C family.

227882:SAVERM RS18525
gene id: 227882:SAVERM_RS18525
uniprot id: Q820G3
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

227882:SAVERM RS33095
gene id: 227882:SAVERM_RS33095
uniprot id: Q829H4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SURF1 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

227882:SAVERM RS24800
gene id: 227882:SAVERM_RS24800
uniprot id: Q82E11
names: Similarity
messages: Belongs to the iron/ascorbate-dependent oxidoreductase family.

227882:SAVERM RS31035
gene id: 227882:SAVERM_RS31035
uniprot id: Q82AN4
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

227882:SAVERM RS20285
gene id: 227882:SAVERM_RS20285
uniprot id: Q82GG6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

227882:SAVERM RS28830
gene id: 227882:SAVERM_RS28830
uniprot id: Q82BW7
names: Subcellular Location Annotation
messages: Membrane

227882:SAVERM RS17805
gene id: 227882:SAVERM_RS17805
uniprot id: Q82HR6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

227882:SAVERM RS03575
gene id: 227882:SAVERM_RS03575
uniprot id: Q82QA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

227882:SAVERM RS18115
gene id: 227882:SAVERM_RS18115
uniprot id: Q82HK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

227882:SAVERM RS13520
gene id: 227882:SAVERM_RS13520
uniprot id: Q82K09
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of aminodeoxyfutalosine (AFL) into futalosine (FL), a step in the biosynthesis of menaquinone (MK, vitamin K2). To a lesser extent, can also deaminate adenosine, 5'-methylthioadenosine, 5'-deoxyadenosine, and 2'-deoxyadenosine.

227882:SAVERM RS13705
gene id: 227882:SAVERM_RS13705
uniprot id: Q82JX2
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

227882:SAVERM RS33315
gene id: 227882:SAVERM_RS33315
uniprot id: Q829C9
names: Similarity
messages: Belongs to the band 7/mec-2 family.

227882:SAVERM RS34380
gene id: 227882:SAVERM_RS34380
uniprot id: Q828H7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

227882:SAVERM RS25220
gene id: 227882:SAVERM_RS25220
uniprot id: Q82DT0
names: Subcellular Location Annotation
messages: Membrane

227882:SAVERM RS05025
gene id: 227882:SAVERM_RS05025
uniprot id: Q82PJ3
names: Similarity
names: Subunit
messages: Belongs to the sigma-70 factor family. ECF subfamily.
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

227882:SAVERM RS15105
gene id: 227882:SAVERM_RS15105
uniprot id: Q82J74
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

227882:SAVERM RS35145
gene id: 227882:SAVERM_RS35145
uniprot id: Q827T6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

227882:SAVERM RS33665
gene id: 227882:SAVERM_RS33665
uniprot id: Q828W2
names: Similarity
messages: Belongs to the NtaA/SnaA/DszA monooxygenase family.

227882:SAVERM RS13050
gene id: 227882:SAVERM_RS13050
uniprot id: Q82K99
names: Similarity
messages: Belongs to the Dps family.

227882:SAVERM RS33670
gene id: 227882:SAVERM_RS33670
uniprot id: Q828W1
names: Similarity
messages: Belongs to the NtaA/SnaA/DszA monooxygenase family.

227882:SAVERM RS17090
gene id: 227882:SAVERM_RS17090
uniprot id: Q82I56
names: Similarity
messages: Belongs to the serine/threonine dehydratase family.

227882:SAVERM RS08925
gene id: 227882:SAVERM_RS08925
uniprot id: Q82MH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SsgA family.
messages: Cell septum

227882:SAVERM RS27275
gene id: 227882:SAVERM_RS27275
uniprot id: Q82CQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

227882:SAVERM RS29185
gene id: 227882:SAVERM_RS29185
uniprot id: Q82BP7
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Catalyzes the reversible hydration of carbon dioxide to form bicarbonate.
messages: Reversible hydration of carbon dioxide.

227882:SAVERM RS20300
gene id: 227882:SAVERM_RS20300
uniprot id: Q82GG3
names: Function
names: Similarity
messages: Belongs to the threonine synthase family.
messages: Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.

227882:SAVERM RS17215
gene id: 227882:SAVERM_RS17215
uniprot id: Q82I33
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAL/histidase family.
messages: Contains an active site 4-methylidene-imidazol-5-one (MIO), which is formed autocatalytically by cyclization and dehydration of residues Cys-Ser-Gly.
messages: Cytoplasm

227882:SAVERM RS22325
gene id: 227882:SAVERM_RS22325
uniprot id: Q82FD5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

227882:SAVERM RS33405
gene id: 227882:SAVERM_RS33405
uniprot id: Q829B5
names: Similarity
messages: Belongs to the TlyA family.

227882:SAVERM RS08865
gene id: 227882:SAVERM_RS08865
uniprot id: Q82MI5
names: Similarity
messages: Belongs to the peptidase M1 family.

227882:SAVERM RS29515
gene id: 227882:SAVERM_RS29515
uniprot id: Q82BI4
names: Similarity
messages: Belongs to the peptidase S8 family.

227882:SAVERM RS22100
gene id: 227882:SAVERM_RS22100
uniprot id: Q82FH8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

227882:SAVERM RS14630
gene id: 227882:SAVERM_RS14630
uniprot id: Q82JE3
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
messages: Cytoplasm
messages: The 20S proteasome core is composed of 14 alpha and 14 beta subunits that assemble into four stacked heptameric rings, resulting in a barrel-shaped structure. The two inner rings, each composed of seven catalytic beta subunits, are sandwiched by two outer rings, each composed of seven alpha subunits. The catalytic chamber with the active sites is on the inside of the barrel. Has a gated structure, the ends of the cylinder being occluded by the N-termini of the alpha-subunits. Is capped by the proteasome-associated ATPase, ARC.
messages: The formation of the proteasomal ATPase ARC-20S proteasome complex, likely via the docking of the C-termini of ARC into the intersubunit pockets in the alpha-rings, may trigger opening of the gate for substrate entry. Interconversion between the open-gate and close-gate conformations leads to a dynamic regulation of the 20S proteasome proteolysis activity.

227882:SAVERM RS28235
gene id: 227882:SAVERM_RS28235
uniprot id: Q82C85
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

227882:SAVERM RS13280
gene id: 227882:SAVERM_RS13280
uniprot id: Q82K58
names: Similarity
messages: Belongs to the ribF family.

227882:SAVERM RS29195
gene id: 227882:SAVERM_RS29195
uniprot id: Q82BP5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

227882:SAVERM RS32885
gene id: 227882:SAVERM_RS32885
uniprot id: Q829L6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PhyH family. EctD subfamily.
messages: Binds 1 Fe(2+) ion.
messages: Homodimer.
messages: Involved in the biosynthesis of 5-hydroxyectoine, called compatible solute, which helps organisms to survive extreme osmotic stress by acting as a highly soluble organic osmolyte. Catalyzes the 2-oxoglutarate-dependent selective hydroxylation of L-ectoine to yield (4S,5S)-5-hydroxyectoine.

227882:SAVERM RS12965
gene id: 227882:SAVERM_RS12965
uniprot id: Q82KB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

227882:SAVERM RS31665
gene id: 227882:SAVERM_RS31665
uniprot id: Q82AB0
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

227882:SAVERM RS21340
gene id: 227882:SAVERM_RS21340
uniprot id: Q82FX0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
messages: Cytoplasm
messages: Homodimer.

227882:SAVERM RS25005
gene id: 227882:SAVERM_RS25005
uniprot id: Q82DX2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

227882:SAVERM RS32050
gene id: 227882:SAVERM_RS32050
uniprot id: Q82A32
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.

227882:SAVERM RS26680
gene id: 227882:SAVERM_RS26680
uniprot id: Q82D17
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

227882:SAVERM RS06850
gene id: 227882:SAVERM_RS06850
uniprot id: Q82NM7
names: Similarity
messages: Belongs to the universal stress protein A family.

227882:SAVERM RS36600
gene id: 227882:SAVERM_RS36600
uniprot id: Q826Q1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MurCDEF family. MurT subfamily.
messages: Forms a heterodimer with GatD.
messages: The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The MurT subunit catalyzes the ATP-dependent amidation of D-glutamate residue of lipid II, converting it to an isoglutamine residue.

227882:SAVERM RS14975
gene id: 227882:SAVERM_RS14975
uniprot id: Q82J83
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

227882:SAVERM RS03450
gene id: 227882:SAVERM_RS03450
uniprot id: Q82QB9
names: Function
names: Subcellular Location Annotation
messages: May play a structural or regulatory role in gas vesicle synthesis.
messages: Vesicle
messages: gas vesicle

227882:SAVERM RS27260
gene id: 227882:SAVERM_RS27260
uniprot id: Q82CR2
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

227882:SAVERM RS29280
gene id: 227882:SAVERM_RS29280
uniprot id: Q82BM8
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

227882:SAVERM RS35295
gene id: 227882:SAVERM_RS35295
uniprot id: Q827Q7
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

227882:SAVERM RS10090
gene id: 227882:SAVERM_RS10090
uniprot id: Q82LU5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

227882:SAVERM RS15540
gene id: 227882:SAVERM_RS15540
uniprot id: Q82IZ2
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
messages: Catalyzes the oxidative phosphorylation of glyceraldehyde 3-phosphate (G3P) to 1,3-bisphosphoglycerate (BPG) using the cofactor NAD. The first reaction step involves the formation of a hemiacetal intermediate between G3P and a cysteine residue, and this hemiacetal intermediate is then oxidized to a thioester, with concomitant reduction of NAD to NADH. The reduced NADH is then exchanged with the second NAD, and the thioester is attacked by a nucleophilic inorganic phosphate to produce BPG.
messages: Cytoplasm
messages: Homotetramer.
messages: Resistant to pentalenolactone.

227882:SAVERM RS25465
gene id: 227882:SAVERM_RS25465
uniprot id: Q82DN7
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

227882:SAVERM RS05640
gene id: 227882:SAVERM_RS05640
uniprot id: Q82PA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

227882:SAVERM RS33650
gene id: 227882:SAVERM_RS33650
uniprot id: Q828W5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

227882:SAVERM RS26335
gene id: 227882:SAVERM_RS26335
uniprot id: Q82D79
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in cellular division.

227882:SAVERM RS13800
gene id: 227882:SAVERM_RS13800
uniprot id: Q82JV3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

227882:SAVERM RS03220
gene id: 227882:SAVERM_RS03220
uniprot id: Q82QG1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the GTP cyclohydrolase II family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.

227882:SAVERM RS10465
gene id: 227882:SAVERM_RS10465
uniprot id: Q82LM3
names: Similarity
messages: Belongs to the cytochrome P450 family.

227882:SAVERM RS04960
gene id: 227882:SAVERM_RS04960
uniprot id: Q82PK5
names: Function
messages: Inhibits mammalian alpha-amylases specifically but has no action on plant and microbial alpha-amylases.

227882:SAVERM RS34205
gene id: 227882:SAVERM_RS34205
uniprot id: Q828L2
names: Similarity
messages: Belongs to the BMP lipoprotein family.

227882:SAVERM RS24545
gene id: 227882:SAVERM_RS24545
uniprot id: Q82E63
names: Cofactor
names: Similarity
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.

227882:SAVERM RS17405
gene id: 227882:SAVERM_RS17405
uniprot id: Q82HZ3
names: Similarity
names: Subunit
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
messages: Homodimer.

227882:SAVERM RS31025
gene id: 227882:SAVERM_RS31025
uniprot id: Q82AN6
names: Function
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

227882:SAVERM RS06520
gene id: 227882:SAVERM_RS06520
uniprot id: Q82NT2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

227882:SAVERM RS17045
gene id: 227882:SAVERM_RS17045
uniprot id: Q82I65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

227882:SAVERM RS04255
gene id: 227882:SAVERM_RS04255
uniprot id: Q82PW6
names: Subcellular Location Annotation
messages: Membrane

227882:SAVERM RS16150
gene id: 227882:SAVERM_RS16150
uniprot id: Q82IL9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatB family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

227882:SAVERM RS08350
gene id: 227882:SAVERM_RS08350
uniprot id: Q82MT5
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

227882:SAVERM RS22490
gene id: 227882:SAVERM_RS22490
uniprot id: Q82FB0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

227882:SAVERM RS14725
gene id: 227882:SAVERM_RS14725
uniprot id: Q82JC3
names: Subunit
messages: Heterodimer of an alpha and a beta chain.

227882:SAVERM RS32755
gene id: 227882:SAVERM_RS32755
uniprot id: Q829P0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

227882:SAVERM RS11365
gene id: 227882:SAVERM_RS11365
uniprot id: Q82L47
names: Similarity
messages: Belongs to the cytochrome P450 family.

227882:SAVERM RS34870
gene id: 227882:SAVERM_RS34870
uniprot id: Q827X8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nlpA lipoprotein family.
messages: Membrane

227882:SAVERM RS31050
gene id: 227882:SAVERM_RS31050
uniprot id: Q82AN1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Membrane

227882:SAVERM RS36605
gene id: 227882:SAVERM_RS36605
uniprot id: Q826Q0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

227882:SAVERM RS43425
gene id: 227882:SAVERM_RS43425
uniprot id: Q82BT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

227882:SAVERM RS29890
gene id: 227882:SAVERM_RS29890
uniprot id: Q82BA8
names: Subcellular Location Annotation
messages: Membrane

227882:SAVERM RS11495
gene id: 227882:SAVERM_RS11495
uniprot id: Q82L21
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

227882:SAVERM RS09350
gene id: 227882:SAVERM_RS09350
uniprot id: Q82M89
names: Similarity
messages: Belongs to the 6-phosphogluconate dehydrogenase family.

227882:SAVERM RS14650
gene id: 227882:SAVERM_RS14650
uniprot id: Q82JD9
names: Subcellular Location Annotation
messages: Membrane

227882:SAVERM RS14570
gene id: 227882:SAVERM_RS14570
uniprot id: Q82JF5
names: Function
names: Similarity
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

227882:SAVERM RS17050
gene id: 227882:SAVERM_RS17050
uniprot id: Q82I64
names: Subcellular Location Annotation
messages: Membrane

227882:SAVERM RS14130
gene id: 227882:SAVERM_RS14130
uniprot id: Q82JP4
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

227882:SAVERM RS27195
gene id: 227882:SAVERM_RS27195
uniprot id: Q82CS0
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

227882:SAVERM RS36245
gene id: 227882:SAVERM_RS36245
uniprot id: Q826X0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

227882:SAVERM RS20315
gene id: 227882:SAVERM_RS20315
uniprot id: Q82GG0
names: Function
names: Similarity
messages: Belongs to the trehalose phosphatase family.
messages: Removes the phosphate from trehalose 6-phosphate to produce free trehalose.

227882:SAVERM RS04315
gene id: 227882:SAVERM_RS04315
uniprot id: Q82PV2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

227882:SAVERM RS13670
gene id: 227882:SAVERM_RS13670
uniprot id: Q82JX9
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by GTP. Inhibited by UTP.
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.

227882:SAVERM RS29700
gene id: 227882:SAVERM_RS29700
uniprot id: Q82BE6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An FAD-requiring monooxygenase active on some tetracycline antibiotic derivatives, which leads to their inactivation. Hydroxylates carbon 11a of tetracycline and some analogs.
messages: Belongs to the aromatic-ring hydroxylase family. TetX subfamily.
messages: Consists of an N-terminal FAD-binding domain with a Rossman fold and a C-terminal substrate-binding domain.
messages: Cytoplasm
messages: Monomer.

227882:SAVERM RS33620
gene id: 227882:SAVERM_RS33620
uniprot id: Q828X1
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

227882:SAVERM RS18200
gene id: 227882:SAVERM_RS18200
uniprot id: Q82HI5
names: Subcellular Location Annotation
messages: Membrane

227882:SAVERM RS17025
gene id: 227882:SAVERM_RS17025
uniprot id: Q82I69
names: Subcellular Location Annotation
messages: Membrane

227882:SAVERM RS31635
gene id: 227882:SAVERM_RS31635
uniprot id: Q82AB6
names: Subcellular Location Annotation
messages: Cytoplasm

227882:SAVERM RS12425
gene id: 227882:SAVERM_RS12425
uniprot id: Q79ZF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

227882:SAVERM RS31905
gene id: 227882:SAVERM_RS31905
uniprot id: Q82A60
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

227882:SAVERM RS34000
gene id: 227882:SAVERM_RS34000
uniprot id: Q828P5
names: Subcellular Location Annotation
messages: Membrane

227882:SAVERM RS06420
gene id: 227882:SAVERM_RS06420
uniprot id: Q82NV4
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

227882:SAVERM RS31985
gene id: 227882:SAVERM_RS31985
uniprot id: Q82A44
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

227882:SAVERM RS31850
gene id: 227882:SAVERM_RS31850
uniprot id: Q82A71
names: Subcellular Location Annotation
messages: Membrane

227882:SAVERM RS17420
gene id: 227882:SAVERM_RS17420
uniprot id: Q82HZ0
names: Subcellular Location Annotation
messages: Membrane

227882:SAVERM RS34195
gene id: 227882:SAVERM_RS34195
uniprot id: Q828L4
names: Subcellular Location Annotation
messages: Membrane

227882:SAVERM RS10095
gene id: 227882:SAVERM_RS10095
uniprot id: Q82LU4
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain.

227882:SAVERM RS07315
gene id: 227882:SAVERM_RS07315
uniprot id: Q82ND3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

227882:SAVERM RS05070
gene id: 227882:SAVERM_RS05070
uniprot id: Q82PI4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system and for the release of the potassium ions to the cytoplasm.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

227882:SAVERM RS25990
gene id: 227882:SAVERM_RS25990
uniprot id: Q82DE2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CofD family.
messages: Catalyzes the transfer of the phosphoenolpyruvate moiety from enoylpyruvoyl-2-diphospho-5'-guanosine (EPPG) to 7,8-didemethyl-8-hydroxy-5-deazariboflavin (FO) with the formation of dehydro coenzyme F420-0 and GMP.
messages: Homodimer.

227882:SAVERM RS27280
gene id: 227882:SAVERM_RS27280
uniprot id: Q82CQ8
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.

227882:SAVERM RS13215
gene id: 227882:SAVERM_RS13215
uniprot id: Q82K72
names: Similarity
messages: Belongs to the WXG100 family.

227882:SAVERM RS09475
gene id: 227882:SAVERM_RS09475
uniprot id: Q82M64
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.

227882:SAVERM RS29735
gene id: 227882:SAVERM_RS29735
uniprot id: Q82BD9
names: Similarity
messages: Belongs to the aldose epimerase family.

227882:SAVERM RS14405
gene id: 227882:SAVERM_RS14405
uniprot id: Q82JI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

227882:SAVERM RS12975
gene id: 227882:SAVERM_RS12975
uniprot id: Q82KB4
names: Similarity
messages: Belongs to the cysteine dioxygenase family.

227882:SAVERM RS15665
gene id: 227882:SAVERM_RS15665
uniprot id: Q82IW6
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

227882:SAVERM RS07340
gene id: 227882:SAVERM_RS07340
uniprot id: Q82NC8
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

227882:SAVERM RS25340
gene id: 227882:SAVERM_RS25340
uniprot id: Q82DR1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

227882:SAVERM RS22565
gene id: 227882:SAVERM_RS22565
uniprot id: Q82F96
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

227882:SAVERM RS17260
gene id: 227882:SAVERM_RS17260
uniprot id: Q82I23
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family.
messages: Cytoplasm
messages: Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

227882:SAVERM RS22760
gene id: 227882:SAVERM_RS22760
uniprot id: Q82F60
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Monomer.

227882:SAVERM RS10440
gene id: 227882:SAVERM_RS10440
uniprot id: Q82LM8
names: Subcellular Location Annotation
messages: Membrane

227882:SAVERM RS01315
gene id: 227882:SAVERM_RS01315
uniprot id: Q82RG5
names: Similarity
messages: Belongs to the peptidase C40 family.

227882:SAVERM RS26130
gene id: 227882:SAVERM_RS26130
uniprot id: Q82DB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpqB lipoprotein family.
messages: Cell membrane

227882:SAVERM RS13395
gene id: 227882:SAVERM_RS13395
uniprot id: Q82K36
names: Similarity
messages: Belongs to the glycosyl hydrolase 12 (cellulase H) family.

227882:SAVERM RS25770
gene id: 227882:SAVERM_RS25770
uniprot id: Q82DI1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

227882:SAVERM RS12805
gene id: 227882:SAVERM_RS12805
uniprot id: Q82KE8
names: Subcellular Location Annotation
messages: Membrane

227882:SAVERM RS26210
gene id: 227882:SAVERM_RS26210
uniprot id: Q82DA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

227882:SAVERM RS13430
gene id: 227882:SAVERM_RS13430
uniprot id: Q82K29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

227882:SAVERM RS26725
gene id: 227882:SAVERM_RS26725
uniprot id: Q820G0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Heptamer of 7 subunits arranged in a ring.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

227882:SAVERM RS25580
gene id: 227882:SAVERM_RS25580
uniprot id: Q82DL9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

227882:SAVERM RS35115
gene id: 227882:SAVERM_RS35115
uniprot id: Q827T9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

227882:SAVERM RS19545
gene id: 227882:SAVERM_RS19545
uniprot id: Q82GW4
names: Subcellular Location Annotation
messages: Membrane

227882:SAVERM RS32915
gene id: 227882:SAVERM_RS32915
uniprot id: Q829L0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

227882:SAVERM RS16740
gene id: 227882:SAVERM_RS16740
uniprot id: Q82IC5
names: Function
names: Similarity
names: Subunit
messages: Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity.
messages: Belongs to the AhpD family.
messages: Homotrimer.

227882:SAVERM RS32395
gene id: 227882:SAVERM_RS32395
uniprot id: Q829W2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

227882:SAVERM RS23735
gene id: 227882:SAVERM_RS23735
uniprot id: Q82EL9
names: Subcellular Location Annotation
messages: Membrane

227882:SAVERM RS34190
gene id: 227882:SAVERM_RS34190
uniprot id: Q828L5
names: Subcellular Location Annotation
messages: Membrane

227882:SAVERM RS23750
gene id: 227882:SAVERM_RS23750
uniprot id: Q82EL6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

227882:SAVERM RS13345
gene id: 227882:SAVERM_RS13345
uniprot id: Q82K46
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

227882:SAVERM RS15125
gene id: 227882:SAVERM_RS15125
uniprot id: Q82J70
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

227882:SAVERM RS21180
gene id: 227882:SAVERM_RS21180
uniprot id: Q82FZ5
names: Subcellular Location Annotation
messages: Membrane

227882:SAVERM RS21550
gene id: 227882:SAVERM_RS21550
uniprot id: Q82FT2
names: Function
messages: Acyltransferase required for the direct transfer of medium- to long-chain fatty acyl moieties from a carrier protein (MbtL) on to the epsilon-amino group of lysine residue in the mycobactin core.

227882:SAVERM RS34965
gene id: 227882:SAVERM_RS34965
uniprot id: Q827W6
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

227882:SAVERM RS30950
gene id: 227882:SAVERM_RS30950
uniprot id: Q82AQ1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glutamine synthetase family.
messages: Cytoplasm
messages: Oligomer of 12 subunits arranged in the form of two hexagons.

227882:SAVERM RS33170
gene id: 227882:SAVERM_RS33170
uniprot id: Q829F9
names: Similarity
messages: Belongs to the peptidase S8 family.

227882:SAVERM RS37880
gene id: 227882:SAVERM_RS37880
uniprot id: Q825T0
names: Similarity
messages: Belongs to the HypD family.

227882:SAVERM RS02810
gene id: 227882:SAVERM_RS02810
uniprot id: Q82QP6
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

227882:SAVERM RS34605
gene id: 227882:SAVERM_RS34605
uniprot id: Q828D1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

227882:SAVERM RS22395
gene id: 227882:SAVERM_RS22395
uniprot id: Q93JL8
names: Disruption Phenotype
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrgA family.
messages: Cell membrane
messages: Inactivation of the gene abolishes most sporulation septation in aerial hyphae.
messages: Involved in cell division. Coordinates growth and cell division. Required for the formation of the sporulation septa.

227882:SAVERM RS03270
gene id: 227882:SAVERM_RS03270
uniprot id: Q82QF4
names: Similarity
messages: Belongs to the glycosyl hydrolase 12 (cellulase H) family.

227882:SAVERM RS32275
gene id: 227882:SAVERM_RS32275
uniprot id: Q829Y6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

227882:SAVERM RS18600
gene id: 227882:SAVERM_RS18600
uniprot id: Q82HA9
names: Similarity
messages: Belongs to the group II decarboxylase family.

227882:SAVERM RS06130
gene id: 227882:SAVERM_RS06130
uniprot id: Q82P05
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M4 family.
messages: Extracellular zinc metalloprotease.
messages: Secreted

227882:SAVERM RS14870
gene id: 227882:SAVERM_RS14870
uniprot id: Q82JA4
names: Subcellular Location Annotation
messages: Membrane

227882:SAVERM RS03465
gene id: 227882:SAVERM_RS03465
uniprot id: Q82QB6
names: Function
names: Similarity
messages: Belongs to the gas vesicle protein type A family.
messages: Gas vesicles are small, hollow, gas filled protein structures that are found in several microbial planktonic microorganisms. They allow the positioning of the organism at the favorable depth for growth.

227882:SAVERM RS10795
gene id: 227882:SAVERM_RS10795
uniprot id: Q82LF7
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

227882:SAVERM RS22270
gene id: 227882:SAVERM_RS22270
uniprot id: Q82FE5
names: Similarity
messages: Belongs to the ParB family.

227882:SAVERM RS14845
gene id: 227882:SAVERM_RS14845
uniprot id: Q82JA9
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

227882:SAVERM RS25590
gene id: 227882:SAVERM_RS25590
uniprot id: Q82DL7
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

227882:SAVERM RS07865
gene id: 227882:SAVERM_RS07865
uniprot id: Q82N23
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Heterodimer of an alpha and a beta subunit.
messages: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

227882:SAVERM RS31970
gene id: 227882:SAVERM_RS31970
uniprot id: Q82A47
names: Similarity
messages: Belongs to the peptidase M1 family.

227882:SAVERM RS27285
gene id: 227882:SAVERM_RS27285
uniprot id: Q82CQ7
names: Similarity
messages: Belongs to the TPP enzyme family.

227882:SAVERM RS31535
gene id: 227882:SAVERM_RS31535
uniprot id: Q82AD6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsQ/DivIB family. FtsQ subfamily.
messages: Cell membrane
messages: Essential cell division protein.

227882:SAVERM RS23505
gene id: 227882:SAVERM_RS23505
uniprot id: Q82ER4
names: Similarity
messages: Belongs to the glycosyltransferase 2 family.

227882:SAVERM RS35060
gene id: 227882:SAVERM_RS35060
uniprot id: Q827U8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also edits incorrectly charged L-seryl-tRNA(Thr).
messages: Cytoplasm
messages: Homodimer.

227882:SAVERM RS22090
gene id: 227882:SAVERM_RS22090
uniprot id: Q82FI0
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

227882:SAVERM RS36495
gene id: 227882:SAVERM_RS36495
uniprot id: Q826S1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease gamma subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

227882:SAVERM RS25720
gene id: 227882:SAVERM_RS25720
uniprot id: Q82DJ0
names: Similarity
messages: Belongs to the YciI family.

227882:SAVERM RS28755
gene id: 227882:SAVERM_RS28755
uniprot id: Q82BY2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

227882:SAVERM RS35250
gene id: 227882:SAVERM_RS35250
uniprot id: Q827R5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

227882:SAVERM RS10925
gene id: 227882:SAVERM_RS10925
uniprot id: Q82LD1
names: Similarity
messages: Belongs to the TPP enzyme family.

227882:SAVERM RS27850
gene id: 227882:SAVERM_RS27850
uniprot id: Q82CF5
names: Similarity
messages: Belongs to the peptidase M1 family.

227882:SAVERM RS07025
gene id: 227882:SAVERM_RS07025
uniprot id: Q82NJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 87 family.
messages: Membrane

227882:SAVERM RS25460
gene id: 227882:SAVERM_RS25460
uniprot id: Q82DN8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

227882:SAVERM RS35805
gene id: 227882:SAVERM_RS35805
uniprot id: Q827F3
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

227882:SAVERM RS26410
gene id: 227882:SAVERM_RS26410
uniprot id: Q82D65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
messages: Membrane

227882:SAVERM RS14500
gene id: 227882:SAVERM_RS14500
uniprot id: Q82JG9
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

227882:SAVERM RS27455
gene id: 227882:SAVERM_RS27455
uniprot id: Q82CM6
names: Subcellular Location Annotation
messages: Membrane

227882:SAVERM RS05880
gene id: 227882:SAVERM_RS05880
uniprot id: Q82P56
names: Similarity
messages: Belongs to the glycosyl hydrolase 27 family.

227882:SAVERM RS01455
gene id: 227882:SAVERM_RS01455
uniprot id: Q82RD9
names: Subcellular Location Annotation
messages: Membrane

227882:SAVERM RS35215
gene id: 227882:SAVERM_RS35215
uniprot id: Q827S2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase MltG family.
messages: Cell membrane
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

227882:SAVERM RS09390
gene id: 227882:SAVERM_RS09390
uniprot id: Q82M81
names: Subcellular Location Annotation
messages: Membrane

227882:SAVERM RS09805
gene id: 227882:SAVERM_RS09805
uniprot id: Q82M02
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

227882:SAVERM RS37430
gene id: 227882:SAVERM_RS37430
uniprot id: Q826A4
names: Similarity
messages: Belongs to the FPG family.

227882:SAVERM RS03280
gene id: 227882:SAVERM_RS03280
uniprot id: Q82QF2
names: Similarity
messages: Belongs to the glycosyl hydrolase family 6.

227882:SAVERM RS31155
gene id: 227882:SAVERM_RS31155
uniprot id: Q82AL0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Binds a copper A center.
messages: Cell membrane
messages: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) (By similarity).

227882:SAVERM RS34610
gene id: 227882:SAVERM_RS34610
uniprot id: Q828D0
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

227882:SAVERM RS11740
gene id: 227882:SAVERM_RS11740
uniprot id: Q82KX2
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

227882:SAVERM RS27520
gene id: 227882:SAVERM_RS27520
uniprot id: Q82CL4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

227882:SAVERM RS25550
gene id: 227882:SAVERM_RS25550
uniprot id: P59756
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

227882:SAVERM RS38415
gene id: 227882:SAVERM_RS38415
uniprot id: Q825H6
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

227882:SAVERM RS09260
gene id: 227882:SAVERM_RS09260
uniprot id: Q82MA6
names: Cofactor
names: Similarity
messages: Belongs to the glycosyl hydrolase 4 family.
messages: Binds 1 NAD(+) per subunit.

227882:SAVERM RS17300
gene id: 227882:SAVERM_RS17300
uniprot id: Q82I15
names: Similarity
messages: Belongs to the phosphohexose mutase family.

227882:SAVERM RS15835
gene id: 227882:SAVERM_RS15835
uniprot id: Q82IT3
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

227882:SAVERM RS09085
gene id: 227882:SAVERM_RS09085
uniprot id: Q82ME1
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

227882:SAVERM RS25750
gene id: 227882:SAVERM_RS25750
uniprot id: Q82DI5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

227882:SAVERM RS25445
gene id: 227882:SAVERM_RS25445
uniprot id: Q82DP1
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

227882:SAVERM RS23980
gene id: 227882:SAVERM_RS23980
uniprot id: Q82EH1
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
messages: Part of the 50S ribosomal subunit.

227882:SAVERM RS10075
gene id: 227882:SAVERM_RS10075
uniprot id: Q82LU8
names: Subunit
messages: Heterodimer of an alpha and a beta chain.

227882:SAVERM RS25260
gene id: 227882:SAVERM_RS25260
uniprot id: Q82DS2
names: Similarity
messages: Belongs to the UPF0234 family.

227882:SAVERM RS12060
gene id: 227882:SAVERM_RS12060
uniprot id: Q82KR6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

227882:SAVERM RS30295
gene id: 227882:SAVERM_RS30295
uniprot id: Q82B27
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

227882:SAVERM RS32895
gene id: 227882:SAVERM_RS32895
uniprot id: Q829L4
names: Function
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
messages: Catalyzes reversively the conversion of L-aspartate beta-semialdehyde (ASA) to L-2,4-diaminobutyrate (DABA) by transamination with L-glutamate.

227882:SAVERM RS37445
gene id: 227882:SAVERM_RS37445
uniprot id: Q826A1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

227882:SAVERM RS28275
gene id: 227882:SAVERM_RS28275
uniprot id: Q82C76
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

227882:SAVERM RS13675
gene id: 227882:SAVERM_RS13675
uniprot id: Q82JX8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm