225999:CXP39 RS01355
gene id: 225999:CXP39_RS01355
uniprot id: A0A2K9C1V2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

225999:CXP39 RS02145
gene id: 225999:CXP39_RS02145
uniprot id: A0A2K9BNH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

225999:CXP39 RS00555
gene id: 225999:CXP39_RS00555
uniprot id: A0A2K9BIW3
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

225999:CXP39 RS00685
gene id: 225999:CXP39_RS00685
uniprot id: A0A2K9BJ44
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

225999:CXP39 RS03510
gene id: 225999:CXP39_RS03510
uniprot id: A0A2K9BS54
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Membrane

225999:CXP39 RS01075
gene id: 225999:CXP39_RS01075
uniprot id: A0A2K9C537
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

225999:CXP39 RS02285
gene id: 225999:CXP39_RS02285
uniprot id: A0A2K9C2B3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

225999:CXP39 RS02835
gene id: 225999:CXP39_RS02835
uniprot id: A0A2K9BVH4
names: Subcellular Location Annotation
messages: Membrane

225999:CXP39 RS00960
gene id: 225999:CXP39_RS00960
uniprot id: A0A2K9C8N3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

225999:CXP39 RS03700
gene id: 225999:CXP39_RS03700
uniprot id: A0A2K9C318
names: Similarity
messages: Belongs to the LacAB/RpiB family.

225999:CXP39 RS02745
gene id: 225999:CXP39_RS02745
uniprot id: A0A2K9BNT9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

225999:CXP39 RS02215
gene id: 225999:CXP39_RS02215
uniprot id: A0A2K9BK17
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

225999:CXP39 RS01120
gene id: 225999:CXP39_RS01120
uniprot id: A0A2K9BJE0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

225999:CXP39 RS03440
gene id: 225999:CXP39_RS03440
uniprot id: A0A2K9BVS7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

225999:CXP39 RS01370
gene id: 225999:CXP39_RS01370
uniprot id: A0A2K9BR22
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

225999:CXP39 RS00620
gene id: 225999:CXP39_RS00620
uniprot id: A0A2K9CCE4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

225999:CXP39 RS02360
gene id: 225999:CXP39_RS02360
uniprot id: A0A2K9BNL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Membrane

225999:CXP39 RS02950
gene id: 225999:CXP39_RS02950
uniprot id: A0A2K9BNX5
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

225999:CXP39 RS03540
gene id: 225999:CXP39_RS03540
uniprot id: A0A2K9C6C1
names: Similarity
messages: Belongs to the HPrK/P family.

225999:CXP39 RS00525
gene id: 225999:CXP39_RS00525
uniprot id: A0A2K9C8F7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

225999:CXP39 RS03465
gene id: 225999:CXP39_RS03465
uniprot id: A0A2K9C9Z1
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

225999:CXP39 RS00230
gene id: 225999:CXP39_RS00230
uniprot id: A0A2K9C4M5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

225999:CXP39 RS01790
gene id: 225999:CXP39_RS01790
uniprot id: A0A2K9BR90
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

225999:CXP39 RS03565
gene id: 225999:CXP39_RS03565
uniprot id: A0A2K9BS64
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

225999:CXP39 RS03790
gene id: 225999:CXP39_RS03790
uniprot id: A0A2K9BKX5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

225999:CXP39 RS00510
gene id: 225999:CXP39_RS00510
uniprot id: A0A2K9BQK0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

225999:CXP39 RS00705
gene id: 225999:CXP39_RS00705
uniprot id: A0A2K9BUE4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

225999:CXP39 RS02365
gene id: 225999:CXP39_RS02365
uniprot id: A0A2K9CDA2
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

225999:CXP39 RS00820
gene id: 225999:CXP39_RS00820
uniprot id: A0A2K9BJ23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

225999:CXP39 RS00395
gene id: 225999:CXP39_RS00395
uniprot id: A0A2K9C1B4
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

225999:CXP39 RS03595
gene id: 225999:CXP39_RS03595
uniprot id: A0A2K9BZR3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
messages: Belongs to the azoreductase type 1 family.
messages: Binds 1 FMN per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones.

225999:CXP39 RS02515
gene id: 225999:CXP39_RS02515
uniprot id: A0A2K9BVB7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

225999:CXP39 RS02900
gene id: 225999:CXP39_RS02900
uniprot id: A0A2K9BNW6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

225999:CXP39 RS03110
gene id: 225999:CXP39_RS03110
uniprot id: A0A2K9CDP7
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

225999:CXP39 RS01500
gene id: 225999:CXP39_RS01500
uniprot id: A0A2K9BN52
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

225999:CXP39 RS03280
gene id: 225999:CXP39_RS03280
uniprot id: A0A2K9BZL0
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

225999:CXP39 RS00760
gene id: 225999:CXP39_RS00760
uniprot id: A0A2K9BUF5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

225999:CXP39 RS02555
gene id: 225999:CXP39_RS02555
uniprot id: A0A2K9BKA5
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

225999:CXP39 RS00055
gene id: 225999:CXP39_RS00055
uniprot id: A0A2K9CC45
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

225999:CXP39 RS02635
gene id: 225999:CXP39_RS02635
uniprot id: A0A2K9BRQ2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

225999:CXP39 RS03235
gene id: 225999:CXP39_RS03235
uniprot id: A0A2K9C2U0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

225999:CXP39 RS01685
gene id: 225999:CXP39_RS01685
uniprot id: A0A2K9BN86
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

225999:CXP39 RS03935
gene id: 225999:CXP39_RS03935
uniprot id: A0A2K9BSD3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

225999:CXP39 RS00730
gene id: 225999:CXP39_RS00730
uniprot id: A0A2K9CCG4
names: Subcellular Location Annotation
messages: Membrane

225999:CXP39 RS02380
gene id: 225999:CXP39_RS02380
uniprot id: A0A2K9C5S3
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

225999:CXP39 RS02910
gene id: 225999:CXP39_RS02910
uniprot id: A0A2K9C9N8
names: Subcellular Location Annotation
messages: Membrane

225999:CXP39 RS02530
gene id: 225999:CXP39_RS02530
uniprot id: A0A2K9BKA6
names: Subcellular Location Annotation
messages: Cytoplasm

225999:CXP39 RS02985
gene id: 225999:CXP39_RS02985
uniprot id: A0A2K9BVK4
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

225999:CXP39 RS01570
gene id: 225999:CXP39_RS01570
uniprot id: A0A2K9C8Y5
names: Similarity
messages: Belongs to the dihydrofolate reductase family.

225999:CXP39 RS03760
gene id: 225999:CXP39_RS03760
uniprot id: A0A2K9BKZ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

225999:CXP39 RS00090
gene id: 225999:CXP39_RS00090
uniprot id: A0A2K9BU07
names: Subcellular Location Annotation
messages: Membrane

225999:CXP39 RS00650
gene id: 225999:CXP39_RS00650
uniprot id: A0A2K9BUD5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

225999:CXP39 RS00095
gene id: 225999:CXP39_RS00095
uniprot id: A0A2K9BIM7
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

225999:CXP39 RS02300
gene id: 225999:CXP39_RS02300
uniprot id: A0A2K9BRJ2
names: Subcellular Location Annotation
messages: Membrane

225999:CXP39 RS02855
gene id: 225999:CXP39_RS02855
uniprot id: A0A2K9CDJ5
names: Subcellular Location Annotation
messages: Membrane

225999:CXP39 RS01820
gene id: 225999:CXP39_RS01820
uniprot id: A0A2K9BYS9
names: Similarity
messages: Belongs to the peptidase M13 family.

225999:CXP39 RS03270
gene id: 225999:CXP39_RS03270
uniprot id: A0A2K9BKP0
names: Similarity
messages: Belongs to the thioredoxin family.

225999:CXP39 RS00185
gene id: 225999:CXP39_RS00185
uniprot id: A0A2K9BXX9
names: Cofactor
names: Similarity
messages: Belongs to the AlaDH/PNT family.
messages: Binds 1 Mg(2+) ion per subunit.

225999:CXP39 RS00765
gene id: 225999:CXP39_RS00765
uniprot id: A0A2K9BJ12
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

225999:CXP39 RS00455
gene id: 225999:CXP39_RS00455
uniprot id: A0A2K9BIU2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.

225999:CXP39 RS03500
gene id: 225999:CXP39_RS03500
uniprot id: A0A2K9BVT7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

225999:CXP39 RS01170
gene id: 225999:CXP39_RS01170
uniprot id: A0A2K9BJF4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

225999:CXP39 RS00460
gene id: 225999:CXP39_RS00460
uniprot id: A0A2K9BQJ2
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

225999:CXP39 RS02280
gene id: 225999:CXP39_RS02280
uniprot id: A0A2K9BZ24
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

225999:CXP39 RS02250
gene id: 225999:CXP39_RS02250
uniprot id: A0A2K9BNJ8
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

225999:CXP39 RS00465
gene id: 225999:CXP39_RS00465
uniprot id: A0A2K9BML4
names: Function
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

225999:CXP39 RS02020
gene id: 225999:CXP39_RS02020
uniprot id: A0A2K9BYW8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

225999:CXP39 RS00800
gene id: 225999:CXP39_RS00800
uniprot id: A0A2K9C4Y8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

225999:CXP39 RS00690
gene id: 225999:CXP39_RS00690
uniprot id: A0A2K9C4W6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

225999:CXP39 RS03045
gene id: 225999:CXP39_RS03045
uniprot id: A0A2K9BRY4
names: Similarity
messages: Belongs to the lipase/esterase LIP3/BchO family.

225999:CXP39 RS02535
gene id: 225999:CXP39_RS02535
uniprot id: A0A2K9BRN2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecU family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

225999:CXP39 RS02260
gene id: 225999:CXP39_RS02260
uniprot id: A0A2K9C9B1
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

225999:CXP39 RS03780
gene id: 225999:CXP39_RS03780
uniprot id: A0A2K9CA42
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

225999:CXP39 RS03410
gene id: 225999:CXP39_RS03410
uniprot id: A0A2K9CDT7
names: Subcellular Location Annotation
messages: Membrane

225999:CXP39 RS00580
gene id: 225999:CXP39_RS00580
uniprot id: A0A2K9BJ26
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

225999:CXP39 RS01630
gene id: 225999:CXP39_RS01630
uniprot id: A0A2K9BR61
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

225999:CXP39 RS03900
gene id: 225999:CXP39_RS03900
uniprot id: A0A2K9C6J5
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

225999:CXP39 RS02940
gene id: 225999:CXP39_RS02940
uniprot id: A0A2K9BKJ0
names: Subcellular Location Annotation
messages: Membrane

225999:CXP39 RS03145
gene id: 225999:CXP39_RS03145
uniprot id: A0A2K9BKN1
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
messages: Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

225999:CXP39 RS03450
gene id: 225999:CXP39_RS03450
uniprot id: A0A2K9BS44
names: Subcellular Location Annotation
messages: Membrane

225999:CXP39 RS03775
gene id: 225999:CXP39_RS03775
uniprot id: A0A2K9CE09
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

225999:CXP39 RS03100
gene id: 225999:CXP39_RS03100
uniprot id: A0A2K9BRZ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIIB subfamily.
messages: Cell inner membrane
messages: Mediates magnesium influx to the cytosol.

225999:CXP39 RS00865
gene id: 225999:CXP39_RS00865
uniprot id: A0A2K9C1K7
names: Subcellular Location Annotation
messages: Membrane

225999:CXP39 RS00935
gene id: 225999:CXP39_RS00935
uniprot id: A0A2K9BUI3
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.

225999:CXP39 RS00345
gene id: 225999:CXP39_RS00345
uniprot id: A0A2K9BU75
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

225999:CXP39 RS03345
gene id: 225999:CXP39_RS03345
uniprot id: A0A2K9BS22
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

225999:CXP39 RS02740
gene id: 225999:CXP39_RS02740
uniprot id: A0A2K9BRS3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

225999:CXP39 RS00700
gene id: 225999:CXP39_RS00700
uniprot id: A0A2K9C1H7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

225999:CXP39 RS00575
gene id: 225999:CXP39_RS00575
uniprot id: A0A2K9C8G7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

225999:CXP39 RS02135
gene id: 225999:CXP39_RS02135
uniprot id: A0A2K9BK09
names: Activity Regulation
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.

225999:CXP39 RS01135
gene id: 225999:CXP39_RS01135
uniprot id: A0A2K9C1Q4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

225999:CXP39 RS03240
gene id: 225999:CXP39_RS03240
uniprot id: A0A2K9BVP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

225999:CXP39 RS00385
gene id: 225999:CXP39_RS00385
uniprot id: A0A2K9BY29
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

225999:CXP39 RS00360
gene id: 225999:CXP39_RS00360
uniprot id: A0A2K9BMJ2
names: Subcellular Location Annotation
messages: Membrane

225999:CXP39 RS00100
gene id: 225999:CXP39_RS00100
uniprot id: A0A2K9BQC3
names: Similarity
messages: Belongs to the ABC transporter superfamily.

225999:CXP39 RS03470
gene id: 225999:CXP39_RS03470
uniprot id: A0A2K9BKR9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

225999:CXP39 RS03420
gene id: 225999:CXP39_RS03420
uniprot id: A0A2K9BKQ8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

225999:CXP39 RS03715
gene id: 225999:CXP39_RS03715
uniprot id: A0A2K9BS96
names: Subcellular Location Annotation
messages: Membrane

225999:CXP39 RS01195
gene id: 225999:CXP39_RS01195
uniprot id: A0A2K9BJ96
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmG family. TrmFO subfamily.
messages: Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
messages: Cytoplasm

225999:CXP39 RS03630
gene id: 225999:CXP39_RS03630
uniprot id: A0A2K9CA18
names: Similarity
names: Subunit
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
messages: Homodimer.

225999:CXP39 RS00625
gene id: 225999:CXP39_RS00625
uniprot id: A0A2K9C8H8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

225999:CXP39 RS03695
gene id: 225999:CXP39_RS03695
uniprot id: A0A2K9BZT5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

225999:CXP39 RS02220
gene id: 225999:CXP39_RS02220
uniprot id: A0A2K9C5P5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

225999:CXP39 RS02590
gene id: 225999:CXP39_RS02590
uniprot id: A0A2K9BNQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

225999:CXP39 RS00515
gene id: 225999:CXP39_RS00515
uniprot id: A0A2K9BMM4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

225999:CXP39 RS00180
gene id: 225999:CXP39_RS00180
uniprot id: A0A2K9C4L7
names: Subcellular Location Annotation
messages: Membrane

225999:CXP39 RS02710
gene id: 225999:CXP39_RS02710
uniprot id: A0A2K9BKD5
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

225999:CXP39 RS00355
gene id: 225999:CXP39_RS00355
uniprot id: A0A2K9BQH2
names: Subcellular Location Annotation
messages: Membrane

225999:CXP39 RS03665
gene id: 225999:CXP39_RS03665
uniprot id: A0A2K9BS85
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

225999:CXP39 RS01330
gene id: 225999:CXP39_RS01330
uniprot id: A0A2K9CCR9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HsdR family.
messages: Subunit R is required for both nuclease and ATPase activities, but not for modification.
messages: The type I restriction/modification system is composed of three polypeptides R, M and S.

225999:CXP39 RS03360
gene id: 225999:CXP39_RS03360
uniprot id: A0A2K9C9W5
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

225999:CXP39 RS02715
gene id: 225999:CXP39_RS02715
uniprot id: A0A2K9C5X9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

225999:CXP39 RS00195
gene id: 225999:CXP39_RS00195
uniprot id: A0A2K9BU35
names: Similarity
messages: Belongs to the serine/threonine dehydratase family.

225999:CXP39 RS01655
gene id: 225999:CXP39_RS01655
uniprot id: A0A2K9C5D4
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

225999:CXP39 RS00135
gene id: 225999:CXP39_RS00135
uniprot id: A0A2K9C167
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

225999:CXP39 RS00710
gene id: 225999:CXP39_RS00710
uniprot id: A0A2K9BJ00
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

225999:CXP39 RS00410
gene id: 225999:CXP39_RS00410
uniprot id: A0A2K9BQI3
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

225999:CXP39 RS02695
gene id: 225999:CXP39_RS02695
uniprot id: A0A2K9BNS9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

225999:CXP39 RS02495
gene id: 225999:CXP39_RS02495
uniprot id: A0A2K9C5U1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

225999:CXP39 RS00940
gene id: 225999:CXP39_RS00940
uniprot id: A0A2K9BJ47
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Monomer.

225999:CXP39 RS01560
gene id: 225999:CXP39_RS01560
uniprot id: A0A2K9BN65
names: Subcellular Location Annotation
messages: Membrane

225999:CXP39 RS01780
gene id: 225999:CXP39_RS01780
uniprot id: A0A2K9BUX6
names: Similarity
messages: Belongs to the HAM1 NTPase family.

225999:CXP39 RS00635
gene id: 225999:CXP39_RS00635
uniprot id: A0A2K9C4V6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

225999:CXP39 RS00640
gene id: 225999:CXP39_RS00640
uniprot id: A0A2K9BY74
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

225999:CXP39 RS03115
gene id: 225999:CXP39_RS03115
uniprot id: A0A2K9C9T4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

225999:CXP39 RS01785
gene id: 225999:CXP39_RS01785
uniprot id: A0A2K9BJS3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Could methylate the ribose at the nucleotide 34 wobble position in tRNA.
messages: Cytoplasm

225999:CXP39 RS01530
gene id: 225999:CXP39_RS01530
uniprot id: A0A2K9C1X9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

225999:CXP39 RS01275
gene id: 225999:CXP39_RS01275
uniprot id: A0A2K9BN14
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

225999:CXP39 RS03090
gene id: 225999:CXP39_RS03090
uniprot id: A0A2K9BVM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

225999:CXP39 RS03030
gene id: 225999:CXP39_RS03030
uniprot id: A0A2K9C2Q7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

225999:CXP39 RS00335
gene id: 225999:CXP39_RS00335
uniprot id: A0A2K9BY18
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

225999:CXP39 RS00050
gene id: 225999:CXP39_RS00050
uniprot id: A0A2K9BMD8
names: Similarity
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.

225999:CXP39 RS03835
gene id: 225999:CXP39_RS03835
uniprot id: A0A2K9CA59
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

225999:CXP39 RS00190
gene id: 225999:CXP39_RS00190
uniprot id: A0A2K9C177
names: Similarity
messages: Belongs to the RutC family.

225999:CXP39 RS03025
gene id: 225999:CXP39_RS03025
uniprot id: A0A2K9BZG9
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

225999:CXP39 RS00140
gene id: 225999:CXP39_RS00140
uniprot id: A0A2K9BU17
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

225999:CXP39 RS01165
gene id: 225999:CXP39_RS01165
uniprot id: A0A2K9C8S4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

225999:CXP39 RS02490
gene id: 225999:CXP39_RS02490
uniprot id: A0A2K9BK94
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

225999:CXP39 RS03560
gene id: 225999:CXP39_RS03560
uniprot id: A0A2K9BKV3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

225999:CXP39 RS03570
gene id: 225999:CXP39_RS03570
uniprot id: A0A2K9BP79
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

225999:CXP39 RS03735
gene id: 225999:CXP39_RS03735
uniprot id: A0A2K9BKW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

225999:CXP39 RS02650
gene id: 225999:CXP39_RS02650
uniprot id: A0A2K9C9I6
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

225999:CXP39 RS03690
gene id: 225999:CXP39_RS03690
uniprot id: A0A2K9C6F4
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

225999:CXP39 RS01200
gene id: 225999:CXP39_RS01200
uniprot id: A0A2K9BQZ1
names: Cofactor
messages: Binds 1 zinc ion per subunit.

225999:CXP39 RS03660
gene id: 225999:CXP39_RS03660
uniprot id: A0A2K9BKX2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

225999:CXP39 RS00585
gene id: 225999:CXP39_RS00585
uniprot id: A0A2K9C4U6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

225999:CXP39 RS02275
gene id: 225999:CXP39_RS02275
uniprot id: A0A2K9C5Q4
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

225999:CXP39 RS03845
gene id: 225999:CXP39_RS03845
uniprot id: A0A2K9BKZ4
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

225999:CXP39 RS02955
gene id: 225999:CXP39_RS02955
uniprot id: A0A2K9CDL4
names: Function
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.
messages: Catalyzes the ATP-dependent phosphorylation of fructose-l-phosphate to fructose-l,6-bisphosphate.

225999:CXP39 RS00545
gene id: 225999:CXP39_RS00545
uniprot id: A0A2K9C1E4
names: Similarity
messages: Belongs to the ABC transporter superfamily.

225999:CXP39 RS02660
gene id: 225999:CXP39_RS02660
uniprot id: A0A2K9C5X0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

225999:CXP39 RS02840
gene id: 225999:CXP39_RS02840
uniprot id: A0A2K9BKG8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

225999:CXP39 RS02230
gene id: 225999:CXP39_RS02230
uniprot id: A0A2K9C2A3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

225999:CXP39 RS01185
gene id: 225999:CXP39_RS01185
uniprot id: A0A2K9C1S1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

225999:CXP39 RS03710
gene id: 225999:CXP39_RS03710
uniprot id: A0A2K9BKY3
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

225999:CXP39 RS03830
gene id: 225999:CXP39_RS03830
uniprot id: A0A2K9CE23
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

225999:CXP39 RS00435
gene id: 225999:CXP39_RS00435
uniprot id: A0A2K9C4R9
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

225999:CXP39 RS01130
gene id: 225999:CXP39_RS01130
uniprot id: A0A2K9BYF8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

225999:CXP39 RS03055
gene id: 225999:CXP39_RS03055
uniprot id: A0A2K9CDN2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
messages: Consists of three domains: the N-terminal catalytic domain, the anticodon-binding domain and the C-terminal extension.
messages: Cytoplasm
messages: Homodimer.

225999:CXP39 RS00980
gene id: 225999:CXP39_RS00980
uniprot id: A0A2K9C1M8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

225999:CXP39 RS01680
gene id: 225999:CXP39_RS01680
uniprot id: A0A2K9BR71
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

225999:CXP39 RS00535
gene id: 225999:CXP39_RS00535
uniprot id: A0A2K9C4T6
names: Similarity
messages: Belongs to the peptidase M17 family.

225999:CXP39 RS00145
gene id: 225999:CXP39_RS00145
uniprot id: A0A2K9BIN6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
messages: Belongs to the azoreductase type 1 family.
messages: Binds 1 FMN per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones.

225999:CXP39 RS01460
gene id: 225999:CXP39_RS01460
uniprot id: A0A2K9C8W7
names: Subcellular Location Annotation
messages: Membrane

225999:CXP39 RS03525
gene id: 225999:CXP39_RS03525
uniprot id: A0A2K9CDV9
names: Similarity
messages: Belongs to the Lgt family.

225999:CXP39 RS03645
gene id: 225999:CXP39_RS03645
uniprot id: A0A2K9BZS4
names: Similarity
messages: Belongs to the ATPase epsilon chain family.

225999:CXP39 RS00255
gene id: 225999:CXP39_RS00255
uniprot id: A0A2K9BQF4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

225999:CXP39 RS02330
gene id: 225999:CXP39_RS02330
uniprot id: A0A2K9BZ33
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

225999:CXP39 RS00695
gene id: 225999:CXP39_RS00695
uniprot id: A0A2K9BY85
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

225999:CXP39 RS03445
gene id: 225999:CXP39_RS03445
uniprot id: A0A2K9BKS4
names: Subcellular Location Annotation
messages: Membrane

225999:CXP39 RS02235
gene id: 225999:CXP39_RS02235
uniprot id: A0A2K9BV63
names: Subcellular Location Annotation
messages: Membrane

225999:CXP39 RS03010
gene id: 225999:CXP39_RS03010
uniprot id: A0A2K9C9R2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

225999:CXP39 RS03800
gene id: 225999:CXP39_RS03800
uniprot id: A0A2K9BZV7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

225999:CXP39 RS01525
gene id: 225999:CXP39_RS01525
uniprot id: A0A2K9BYM9
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

225999:CXP39 RS02560
gene id: 225999:CXP39_RS02560
uniprot id: A0A2K9C5V0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

225999:CXP39 RS00020
gene id: 225999:CXP39_RS00020
uniprot id: A0A2K9C4I7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ribonuclease M5 family.
messages: Cytoplasm
messages: Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step.

225999:CXP39 RS03840
gene id: 225999:CXP39_RS03840
uniprot id: A0A2K9BSF5
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

225999:CXP39 RS02815
gene id: 225999:CXP39_RS02815
uniprot id: A0A2K9BKF4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

225999:CXP39 RS03820
gene id: 225999:CXP39_RS03820
uniprot id: A0A2K9BSB4
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

225999:CXP39 RS01715
gene id: 225999:CXP39_RS01715
uniprot id: A0A2K9C208
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

225999:CXP39 RS02480
gene id: 225999:CXP39_RS02480
uniprot id: A0A2K9C9F0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein S19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein S19.

225999:CXP39 RS02160
gene id: 225999:CXP39_RS02160
uniprot id: A0A2K9BK07
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

225999:CXP39 RS02705
gene id: 225999:CXP39_RS02705
uniprot id: A0A2K9C9K0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

225999:CXP39 RS03755
gene id: 225999:CXP39_RS03755
uniprot id: A0A2K9BVY5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

225999:CXP39 RS00250
gene id: 225999:CXP39_RS00250
uniprot id: A0A2K9BIQ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

225999:CXP39 RS01645
gene id: 225999:CXP39_RS01645
uniprot id: A0A2K9C8Z9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

225999:CXP39 RS01990
gene id: 225999:CXP39_RS01990
uniprot id: A0A2K9BRD3
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

225999:CXP39 RS00925
gene id: 225999:CXP39_RS00925
uniprot id: A0A2K9BYC4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThiI family.
messages: Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
messages: Cytoplasm

225999:CXP39 RS01125
gene id: 225999:CXP39_RS01125
uniprot id: A0A2K9C545
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

225999:CXP39 RS03005
gene id: 225999:CXP39_RS03005
uniprot id: A0A2K9CDM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family.
messages: Membrane

225999:CXP39 RS03535
gene id: 225999:CXP39_RS03535
uniprot id: A0A2K9BKS9
names: Similarity
messages: Belongs to the Lgt family.

225999:CXP39 RS03000
gene id: 225999:CXP39_RS03000
uniprot id: A0A2K9BNY5
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

225999:CXP39 RS01490
gene id: 225999:CXP39_RS01490
uniprot id: A0A2K9BJJ4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

225999:CXP39 RS01810
gene id: 225999:CXP39_RS01810
uniprot id: A0A2K9BJT5
names: Subcellular Location Annotation
messages: Membrane

225999:CXP39 RS00025
gene id: 225999:CXP39_RS00025
uniprot id: A0A2K9BXV1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

225999:CXP39 RS00995
gene id: 225999:CXP39_RS00995
uniprot id: A0A2K9BQV1
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

225999:CXP39 RS00910
gene id: 225999:CXP39_RS00910
uniprot id: A0A2K9C8M3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

225999:CXP39 RS02025
gene id: 225999:CXP39_RS02025
uniprot id: A0A2K9C265
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvB family.
messages: Forms a complex with RuvA.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.

225999:CXP39 RS03520
gene id: 225999:CXP39_RS03520
uniprot id: A0A2K9BP70
names: Function
names: Similarity
messages: Belongs to the WhiA family.
messages: Involved in cell division and chromosome segregation.

225999:CXP39 RS03505
gene id: 225999:CXP39_RS03505
uniprot id: A0A2K9BKT7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

225999:CXP39 RS02685
gene id: 225999:CXP39_RS02685
uniprot id: A0A2K9BKD8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

225999:CXP39 RS00200
gene id: 225999:CXP39_RS00200
uniprot id: A0A2K9BIP6
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

225999:CXP39 RS03040
gene id: 225999:CXP39_RS03040
uniprot id: A0A2K9BKL0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

225999:CXP39 RS02320
gene id: 225999:CXP39_RS02320
uniprot id: A0A2K9BK57
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

225999:CXP39 RS00015
gene id: 225999:CXP39_RS00015
uniprot id: A0A2K9BIT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm

225999:CXP39 RS03670
gene id: 225999:CXP39_RS03670
uniprot id: A0A2K9BPA1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

225999:CXP39 RS02265
gene id: 225999:CXP39_RS02265
uniprot id: A0A2K9BK50
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

225999:CXP39 RS03435
gene id: 225999:CXP39_RS03435
uniprot id: A0A2K9C2W9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

225999:CXP39 RS01950
gene id: 225999:CXP39_RS01950
uniprot id: A0A2K9CD18
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

225999:CXP39 RS01885
gene id: 225999:CXP39_RS01885
uniprot id: A0A2K9BJU3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

225999:CXP39 RS02100
gene id: 225999:CXP39_RS02100
uniprot id: A0A2K9CD53
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AP endonuclease 2 family.
messages: Binds 3 Zn(2+) ions.
messages: Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.

225999:CXP39 RS02015
gene id: 225999:CXP39_RS02015
uniprot id: A0A2K9C5K0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

225999:CXP39 RS01700
gene id: 225999:CXP39_RS01700
uniprot id: A0A2K9BJR9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

225999:CXP39 RS02355
gene id: 225999:CXP39_RS02355
uniprot id: A0A2K9BRK2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

225999:CXP39 RS02055
gene id: 225999:CXP39_RS02055
uniprot id: A0A2K9C976
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

225999:CXP39 RS00785
gene id: 225999:CXP39_RS00785
uniprot id: A0A2K9CCH4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

225999:CXP39 RS02550
gene id: 225999:CXP39_RS02550
uniprot id: A0A2K9C9G1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

225999:CXP39 RS01535
gene id: 225999:CXP39_RS01535
uniprot id: A0A2K9BUT7
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

225999:CXP39 RS00010
gene id: 225999:CXP39_RS00010
uniprot id: A0A2K9C870
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

225999:CXP39 RS00300
gene id: 225999:CXP39_RS00300
uniprot id: A0A2K9BIR3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

225999:CXP39 RS02110
gene id: 225999:CXP39_RS02110
uniprot id: A0A2K9BJZ7
names: Similarity
messages: Belongs to the TlyA family.

225999:CXP39 RS02240
gene id: 225999:CXP39_RS02240
uniprot id: A0A2K9BK45
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

225999:CXP39 RS01020
gene id: 225999:CXP39_RS01020
uniprot id: A0A2K9C527
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

225999:CXP39 RS02475
gene id: 225999:CXP39_RS02475
uniprot id: A0A2K9CDC5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

225999:CXP39 RS00005
gene id: 225999:CXP39_RS00005
uniprot id: A0A2K9CC35
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

225999:CXP39 RS00735
gene id: 225999:CXP39_RS00735
uniprot id: A0A2K9C8J6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

225999:CXP39 RS03400
gene id: 225999:CXP39_RS03400
uniprot id: A0A2K9BS34
names: Subcellular Location Annotation
messages: Cytoplasm

225999:CXP39 RS00985
gene id: 225999:CXP39_RS00985
uniprot id: A0A2K9BUJ3
names: Similarity
names: Subunit
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Tetramer of two alpha and two beta subunits.

225999:CXP39 RS01480
gene id: 225999:CXP39_RS01480
uniprot id: A0A2K9C1X1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

225999:CXP39 RS03050
gene id: 225999:CXP39_RS03050
uniprot id: A0A2K9BNZ5
names: Similarity
messages: Belongs to the RNase H family.

225999:CXP39 RS03015
gene id: 225999:CXP39_RS03015
uniprot id: A0A2K9BKJ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

225999:CXP39 RS03675
gene id: 225999:CXP39_RS03675
uniprot id: A0A2K9CDY8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

225999:CXP39 RS02510
gene id: 225999:CXP39_RS02510
uniprot id: A0A2K9C2F1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase Y family.
messages: Cell membrane
messages: Endoribonuclease that initiates mRNA decay.

225999:CXP39 RS01905
gene id: 225999:CXP39_RS01905
uniprot id: A0A2K9C947
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uridine kinase family.
messages: Cytoplasm

225999:CXP39 RS00030
gene id: 225999:CXP39_RS00030
uniprot id: A0A2K9C149
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.

225999:CXP39 RS00595
gene id: 225999:CXP39_RS00595
uniprot id: A0A2K9C1F9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

225999:CXP39 RS02105
gene id: 225999:CXP39_RS02105
uniprot id: A0A2K9C983
names: Similarity
messages: Belongs to the NusB family.

225999:CXP39 RS00915
gene id: 225999:CXP39_RS00915
uniprot id: A0A2K9BJ92
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

225999:CXP39 RS03635
gene id: 225999:CXP39_RS03635
uniprot id: A0A2K9BKU7
names: Similarity
messages: Belongs to the phosphohexose mutase family.

225999:CXP39 RS00680
gene id: 225999:CXP39_RS00680
uniprot id: A0A2K9C8I9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.
messages: Cytoplasm
messages: Monomer.

225999:CXP39 RS00600
gene id: 225999:CXP39_RS00600
uniprot id: A0A2K9BUC4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

225999:CXP39 RS02460
gene id: 225999:CXP39_RS02460
uniprot id: A0A2K9BK96
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

225999:CXP39 RS01045
gene id: 225999:CXP39_RS01045
uniprot id: A0A2K9BQW1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

225999:CXP39 RS02185
gene id: 225999:CXP39_RS02185
uniprot id: A0A2K9BV53
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

225999:CXP39 RS00305
gene id: 225999:CXP39_RS00305
uniprot id: A0A2K9BQG4
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

225999:CXP39 RS00240
gene id: 225999:CXP39_RS00240
uniprot id: A0A2K9C187
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

225999:CXP39 RS01725
gene id: 225999:CXP39_RS01725
uniprot id: A0A2K9BUX1
names: Similarity
messages: Belongs to the RibF family.

225999:CXP39 RS01510
gene id: 225999:CXP39_RS01510
uniprot id: A0A2K9C8X5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

225999:CXP39 RS01930
gene id: 225999:CXP39_RS01930
uniprot id: A0A2K9BV03
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 2 subfamily.
messages: Cell membrane
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

225999:CXP39 RS02925
gene id: 225999:CXP39_RS02925
uniprot id: A0A2K9BZE7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

225999:CXP39 RS02440
gene id: 225999:CXP39_RS02440
uniprot id: A0A2K9BZ53
names: Similarity
messages: Belongs to the ABC transporter superfamily.

225999:CXP39 RS01650
gene id: 225999:CXP39_RS01650
uniprot id: A0A2K9BJP2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-C family. PolC subfamily.
messages: Cytoplasm
messages: Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

225999:CXP39 RS02545
gene id: 225999:CXP39_RS02545
uniprot id: A0A2K9CDD9
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

225999:CXP39 RS01475
gene id: 225999:CXP39_RS01475
uniprot id: A0A2K9BYL9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

225999:CXP39 RS02005
gene id: 225999:CXP39_RS02005
uniprot id: A0A2K9C960
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LDH/MDH superfamily. LDH family.
messages: Catalyzes the conversion of lactate to pyruvate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

225999:CXP39 RS02720
gene id: 225999:CXP39_RS02720
uniprot id: A0A2K9BZA3
names: Similarity
messages: Belongs to the FtsK/SpoIIIE/SftA family.

225999:CXP39 RS01080
gene id: 225999:CXP39_RS01080
uniprot id: A0A2K9BYE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

225999:CXP39 RS00645
gene id: 225999:CXP39_RS00645
uniprot id: A0A2K9C1G7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

225999:CXP39 RS01265
gene id: 225999:CXP39_RS01265
uniprot id: A0A2K9BJC0
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.

225999:CXP39 RS02465
gene id: 225999:CXP39_RS02465
uniprot id: A0A2K9BRM2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.
messages: Cytoplasm
messages: Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity.

225999:CXP39 RS03375
gene id: 225999:CXP39_RS03375
uniprot id: A0A2K9C691
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

225999:CXP39 RS03600
gene id: 225999:CXP39_RS03600
uniprot id: A0A2K9C2Z9
names: Similarity
messages: Belongs to the PNP/UDP phosphorylase family.

225999:CXP39 RS00715
gene id: 225999:CXP39_RS00715
uniprot id: A0A2K9BQP2
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

225999:CXP39 RS02995
gene id: 225999:CXP39_RS02995
uniprot id: A0A2K9BRX2
names: Similarity
messages: Belongs to the pyruvate kinase family.

225999:CXP39 RS00330
gene id: 225999:CXP39_RS00330
uniprot id: A0A2K9C4P6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

225999:CXP39 RS00260
gene id: 225999:CXP39_RS00260
uniprot id: A0A2K9BMH6
names: Similarity
messages: Belongs to the phosphate acetyltransferase and butyryltransferase family.

225999:CXP39 RS00520
gene id: 225999:CXP39_RS00520
uniprot id: A0A2K9CCC6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

225999:CXP39 RS03640
gene id: 225999:CXP39_RS03640
uniprot id: A0A2K9C6E3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

225999:CXP39 RS02115
gene id: 225999:CXP39_RS02115
uniprot id: A0A2K9C5M5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

225999:CXP39 RS00400
gene id: 225999:CXP39_RS00400
uniprot id: A0A2K9BU85
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

225999:CXP39 RS00565
gene id: 225999:CXP39_RS00565
uniprot id: A0A2K9BMN3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

225999:CXP39 RS00855
gene id: 225999:CXP39_RS00855
uniprot id: A0A2K9C4Z9
names: Similarity
messages: Belongs to the Fur family.

225999:CXP39 RS03895
gene id: 225999:CXP39_RS03895
uniprot id: A0A2K9BL04
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

225999:CXP39 RS00590
gene id: 225999:CXP39_RS00590
uniprot id: A0A2K9BY64
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

225999:CXP39 RS00660
gene id: 225999:CXP39_RS00660
uniprot id: A0A2K9BQN2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

225999:CXP39 RS00825
gene id: 225999:CXP39_RS00825
uniprot id: A0A2K9BQR8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

225999:CXP39 RS00990
gene id: 225999:CXP39_RS00990
uniprot id: A0A2K9BJ53
names: Function
names: Similarity
messages: Belongs to the NrdI family.
messages: Probably involved in ribonucleotide reductase function.

225999:CXP39 RS00605
gene id: 225999:CXP39_RS00605
uniprot id: A0A2K9BIX3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

225999:CXP39 RS03680
gene id: 225999:CXP39_RS03680
uniprot id: A0A2K9CA27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Membrane

225999:CXP39 RS02580
gene id: 225999:CXP39_RS02580
uniprot id: A0A2K9BKB8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

225999:CXP39 RS00495
gene id: 225999:CXP39_RS00495
uniprot id: A0A2K9C1D4
names: Subcellular Location Annotation
messages: Membrane

225999:CXP39 RS00955
gene id: 225999:CXP39_RS00955
uniprot id: A0A2K9CCK5
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

225999:CXP39 RS02370
gene id: 225999:CXP39_RS02370
uniprot id: A0A2K9C9D0
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

225999:CXP39 RS03530
gene id: 225999:CXP39_RS03530
uniprot id: A0A2K9CA01
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Homodimer.

225999:CXP39 RS03875
gene id: 225999:CXP39_RS03875
uniprot id: A0A2K9BSC4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

225999:CXP39 RS00630
gene id: 225999:CXP39_RS00630
uniprot id: A0A2K9BJ37
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

225999:CXP39 RS01280
gene id: 225999:CXP39_RS01280
uniprot id: A0A2K9CCQ9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

225999:CXP39 RS02450
gene id: 225999:CXP39_RS02450
uniprot id: A0A2K9C2E1
names: Similarity
messages: Belongs to the DprA/Smf family.

225999:CXP39 RS01110
gene id: 225999:CXP39_RS01110
uniprot id: A0A2K9CCN3
names: Similarity
messages: Belongs to the asp23 family.

225999:CXP39 RS02405
gene id: 225999:CXP39_RS02405
uniprot id: A0A2K9BRL2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

225999:CXP39 RS01335
gene id: 225999:CXP39_RS01335
uniprot id: A0A2K9C8U9
names: Similarity
messages: Belongs to the glycosyl hydrolase 53 family.

225999:CXP39 RS03770
gene id: 225999:CXP39_RS03770
uniprot id: A0A2K9BPC3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

225999:CXP39 RS03745
gene id: 225999:CXP39_RS03745
uniprot id: A0A2K9BZU8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

225999:CXP39 RS03125
gene id: 225999:CXP39_RS03125
uniprot id: A0A2K9C659
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

225999:CXP39 RS03655
gene id: 225999:CXP39_RS03655
uniprot id: A0A2K9BVW6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

225999:CXP39 RS02895
gene id: 225999:CXP39_RS02895
uniprot id: A0A2K9BRV0
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

225999:CXP39 RS00040
gene id: 225999:CXP39_RS00040
uniprot id: A0A2K9BIL0
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

225999:CXP39 RS00270
gene id: 225999:CXP39_RS00270
uniprot id: A0A2K9C8B1
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

225999:CXP39 RS02060
gene id: 225999:CXP39_RS02060
uniprot id: A0A2K9BJY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0154 family.
messages: Membrane

225999:CXP39 RS03825
gene id: 225999:CXP39_RS03825
uniprot id: A0A2K9BPD3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

225999:CXP39 RS02885
gene id: 225999:CXP39_RS02885
uniprot id: A0A2K9BVI4
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

225999:CXP39 RS03940
gene id: 225999:CXP39_RS03940
uniprot id: A0A2K9BPF3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

225999:CXP39 RS00570
gene id: 225999:CXP39_RS00570
uniprot id: A0A2K9CCD5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

225999:CXP39 RS02315
gene id: 225999:CXP39_RS02315
uniprot id: A0A2K9C9C3
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

225999:CXP39 RS03815
gene id: 225999:CXP39_RS03815
uniprot id: A0A2K9BKZ9
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

225999:CXP39 RS01105
gene id: 225999:CXP39_RS01105
uniprot id: A0A2K9BMY3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

225999:CXP39 RS00115
gene id: 225999:CXP39_RS00115
uniprot id: A0A2K9C884
names: Subcellular Location Annotation
messages: Membrane

225999:CXP39 RS02665
gene id: 225999:CXP39_RS02665
uniprot id: A0A2K9BZ93
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

225999:CXP39 RS01800
gene id: 225999:CXP39_RS01800
uniprot id: A0A2K9CCY8
names: Subcellular Location Annotation
messages: Membrane

225999:CXP39 RS01730
gene id: 225999:CXP39_RS01730
uniprot id: A0A2K9BJP9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

225999:CXP39 RS03740
gene id: 225999:CXP39_RS03740
uniprot id: A0A2K9C6G4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

225999:CXP39 RS02905
gene id: 225999:CXP39_RS02905
uniprot id: A0A2K9CDK5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-3 family.
messages: Cytoplasm
messages: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
messages: Monomer.

225999:CXP39 RS02225
gene id: 225999:CXP39_RS02225
uniprot id: A0A2K9BZ13
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.