2249356:HYN86 RS03435
gene id: 2249356:HYN86_RS03435
uniprot id: A0A344LP60
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

2249356:HYN86 RS18340
gene id: 2249356:HYN86_RS18340
uniprot id: A0A344LX01
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

2249356:HYN86 RS08955
gene id: 2249356:HYN86_RS08955
uniprot id: A0A344LYM1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

2249356:HYN86 RS09270
gene id: 2249356:HYN86_RS09270
uniprot id: A0A344LS85
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

2249356:HYN86 RS05940
gene id: 2249356:HYN86_RS05940
uniprot id: A0A344LQH4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

2249356:HYN86 RS09285
gene id: 2249356:HYN86_RS09285
uniprot id: A0A344LS87
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

2249356:HYN86 RS00130
gene id: 2249356:HYN86_RS00130
uniprot id: A0A344LMF8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

2249356:HYN86 RS17405
gene id: 2249356:HYN86_RS17405
uniprot id: A0A344LWI0
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

2249356:HYN86 RS13620
gene id: 2249356:HYN86_RS13620
uniprot id: A0A344LUI4
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

2249356:HYN86 RS17250
gene id: 2249356:HYN86_RS17250
uniprot id: A0A344LWF2
names: Function
messages: Might have a role analogous to that of eukaryotic histone proteins.

2249356:HYN86 RS04810
gene id: 2249356:HYN86_RS04810
uniprot id: A0A344LPW8
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

2249356:HYN86 RS04775
gene id: 2249356:HYN86_RS04775
uniprot id: A0A344LPW1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

2249356:HYN86 RS05655
gene id: 2249356:HYN86_RS05655
uniprot id: A0A344LQB8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

2249356:HYN86 RS06780
gene id: 2249356:HYN86_RS06780
uniprot id: A0A344LQX7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.

2249356:HYN86 RS20375
gene id: 2249356:HYN86_RS20375
uniprot id: A0A344LY20
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
messages: Cytoplasm

2249356:HYN86 RS12615
gene id: 2249356:HYN86_RS12615
uniprot id: A0A344LTZ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

2249356:HYN86 RS02975
gene id: 2249356:HYN86_RS02975
uniprot id: A0A344LNX8
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

2249356:HYN86 RS15365
gene id: 2249356:HYN86_RS15365
uniprot id: A0A344LVF9
names: Similarity
messages: Belongs to the CvfB family.

2249356:HYN86 RS01965
gene id: 2249356:HYN86_RS01965
uniprot id: A0A344LNE4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

2249356:HYN86 RS12610
gene id: 2249356:HYN86_RS12610
uniprot id: A0A344LTZ5
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

2249356:HYN86 RS14805
gene id: 2249356:HYN86_RS14805
uniprot id: A0A344LV54
names: Similarity
messages: Belongs to the AlaDH/PNT family.

2249356:HYN86 RS02825
gene id: 2249356:HYN86_RS02825
uniprot id: A0A344LNV0
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2249356:HYN86 RS01845
gene id: 2249356:HYN86_RS01845
uniprot id: A0A344LNC1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

2249356:HYN86 RS05610
gene id: 2249356:HYN86_RS05610
uniprot id: A0A344LQA9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

2249356:HYN86 RS11740
gene id: 2249356:HYN86_RS11740
uniprot id: A0A344LTI3
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

2249356:HYN86 RS01920
gene id: 2249356:HYN86_RS01920
uniprot id: A0A344LND5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

2249356:HYN86 RS00625
gene id: 2249356:HYN86_RS00625
uniprot id: A0A344LMP6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2249356:HYN86 RS20590
gene id: 2249356:HYN86_RS20590
uniprot id: A0A344LY61
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

2249356:HYN86 RS02535
gene id: 2249356:HYN86_RS02535
uniprot id: A0A344LNP3
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.

2249356:HYN86 RS00005
gene id: 2249356:HYN86_RS00005
uniprot id: A0A344LMD9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

2249356:HYN86 RS01980
gene id: 2249356:HYN86_RS01980
uniprot id: A0A344LNE7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

2249356:HYN86 RS12545
gene id: 2249356:HYN86_RS12545
uniprot id: A0A344LTY2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

2249356:HYN86 RS12460
gene id: 2249356:HYN86_RS12460
uniprot id: A0A344LTW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

2249356:HYN86 RS10385
gene id: 2249356:HYN86_RS10385
uniprot id: A0A344LST7
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

2249356:HYN86 RS09315
gene id: 2249356:HYN86_RS09315
uniprot id: A0A344LS93
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

2249356:HYN86 RS01935
gene id: 2249356:HYN86_RS01935
uniprot id: A0A344LND8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

2249356:HYN86 RS12215
gene id: 2249356:HYN86_RS12215
uniprot id: A0A344LTS5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

2249356:HYN86 RS05010
gene id: 2249356:HYN86_RS05010
uniprot id: A0A344LQ04
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

2249356:HYN86 RS08620
gene id: 2249356:HYN86_RS08620
uniprot id: A0A344LRW7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

2249356:HYN86 RS12010
gene id: 2249356:HYN86_RS12010
uniprot id: A0A344LTN6
names: Similarity
messages: Belongs to the UPF0111 family.

2249356:HYN86 RS01950
gene id: 2249356:HYN86_RS01950
uniprot id: A0A344LNE1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

2249356:HYN86 RS06960
gene id: 2249356:HYN86_RS06960
uniprot id: A0A344LR12
names: Similarity
messages: Belongs to the PAPS reductase family. CysD subfamily.

2249356:HYN86 RS01835
gene id: 2249356:HYN86_RS01835
uniprot id: A0A344LNB9
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

2249356:HYN86 RS00085
gene id: 2249356:HYN86_RS00085
uniprot id: A0A344LMF4
names: Similarity
messages: Belongs to the AlaDH/PNT family.

2249356:HYN86 RS00495
gene id: 2249356:HYN86_RS00495
uniprot id: A0A344LMM1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

2249356:HYN86 RS01860
gene id: 2249356:HYN86_RS01860
uniprot id: A0A344LNC4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

2249356:HYN86 RS09300
gene id: 2249356:HYN86_RS09300
uniprot id: A0A344LS90
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

2249356:HYN86 RS01925
gene id: 2249356:HYN86_RS01925
uniprot id: A0A344LND6
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

2249356:HYN86 RS08720
gene id: 2249356:HYN86_RS08720
uniprot id: A0A344LRY6
names: Similarity
messages: Belongs to the TelA family.

2249356:HYN86 RS12150
gene id: 2249356:HYN86_RS12150
uniprot id: A0A344LTR2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein L14 (rplN).

2249356:HYN86 RS06840
gene id: 2249356:HYN86_RS06840
uniprot id: A0A344LQY9
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.

2249356:HYN86 RS07165
gene id: 2249356:HYN86_RS07165
uniprot id: A0A344LR51
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

2249356:HYN86 RS13590
gene id: 2249356:HYN86_RS13590
uniprot id: A0A344LUH8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2249356:HYN86 RS01930
gene id: 2249356:HYN86_RS01930
uniprot id: A0A344LND7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

2249356:HYN86 RS04955
gene id: 2249356:HYN86_RS04955
uniprot id: A0A344LPZ5
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

2249356:HYN86 RS07595
gene id: 2249356:HYN86_RS07595
uniprot id: A0A344LRD4
names: Similarity
messages: Belongs to the thioredoxin family.

2249356:HYN86 RS06755
gene id: 2249356:HYN86_RS06755
uniprot id: A0A344LQX2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2249356:HYN86 RS20585
gene id: 2249356:HYN86_RS20585
uniprot id: A0A344LY60
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

2249356:HYN86 RS01820
gene id: 2249356:HYN86_RS01820
uniprot id: A0A344LNB6
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

2249356:HYN86 RS12770
gene id: 2249356:HYN86_RS12770
uniprot id: A0A344LU27
names: Similarity
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

2249356:HYN86 RS00030
gene id: 2249356:HYN86_RS00030
uniprot id: A0A344LME3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uridine kinase family.
messages: Cytoplasm

2249356:HYN86 RS02105
gene id: 2249356:HYN86_RS02105
uniprot id: A0A344LNG8
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

2249356:HYN86 RS08645
gene id: 2249356:HYN86_RS08645
uniprot id: A0A344LRX2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

2249356:HYN86 RS01955
gene id: 2249356:HYN86_RS01955
uniprot id: A0A344LNE2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

2249356:HYN86 RS09295
gene id: 2249356:HYN86_RS09295
uniprot id: A0A344LS89
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

2249356:HYN86 RS01865
gene id: 2249356:HYN86_RS01865
uniprot id: A0A344LNC5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

2249356:HYN86 RS02240
gene id: 2249356:HYN86_RS02240
uniprot id: A0A344LNJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

2249356:HYN86 RS01915
gene id: 2249356:HYN86_RS01915
uniprot id: A0A344LND4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

2249356:HYN86 RS06775
gene id: 2249356:HYN86_RS06775
uniprot id: A0A344LQX6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2249356:HYN86 RS00525
gene id: 2249356:HYN86_RS00525
uniprot id: A0A344LMM6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL31 family.

2249356:HYN86 RS06155
gene id: 2249356:HYN86_RS06155
uniprot id: A0A344LQL3
names: Similarity
messages: Belongs to the thioredoxin family.

2249356:HYN86 RS10810
gene id: 2249356:HYN86_RS10810
uniprot id: A0A344LT15
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

2249356:HYN86 RS05475
gene id: 2249356:HYN86_RS05475
uniprot id: A0A344LQ87
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

2249356:HYN86 RS09310
gene id: 2249356:HYN86_RS09310
uniprot id: A0A344LS92
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

2249356:HYN86 RS18420
gene id: 2249356:HYN86_RS18420
uniprot id: A0A344LX17
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 3B subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

2249356:HYN86 RS00665
gene id: 2249356:HYN86_RS00665
uniprot id: A0A344LMQ4
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

2249356:HYN86 RS05660
gene id: 2249356:HYN86_RS05660
uniprot id: A0A344LQB9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

2249356:HYN86 RS07115
gene id: 2249356:HYN86_RS07115
uniprot id: A0A344LR42
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

2249356:HYN86 RS12795
gene id: 2249356:HYN86_RS12795
uniprot id: A0A344LU32
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

2249356:HYN86 RS00200
gene id: 2249356:HYN86_RS00200
uniprot id: A0A344LMH1
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

2249356:HYN86 RS04220
gene id: 2249356:HYN86_RS04220
uniprot id: A0A344LPK8
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

2249356:HYN86 RS15560
gene id: 2249356:HYN86_RS15560
uniprot id: A0A344LVJ8
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS1 family.
messages: Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.

2249356:HYN86 RS07540
gene id: 2249356:HYN86_RS07540
uniprot id: A0A344LRC3
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

2249356:HYN86 RS05220
gene id: 2249356:HYN86_RS05220
uniprot id: A0A344LQ42
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

2249356:HYN86 RS01940
gene id: 2249356:HYN86_RS01940
uniprot id: A0A344LND9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

2249356:HYN86 RS01855
gene id: 2249356:HYN86_RS01855
uniprot id: A0A344LNC3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

2249356:HYN86 RS15070
gene id: 2249356:HYN86_RS15070
uniprot id: A0A344LVA3
names: Similarity
messages: Belongs to the SUI1 family.

2249356:HYN86 RS11205
gene id: 2249356:HYN86_RS11205
uniprot id: A0A344LT89
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

2249356:HYN86 RS01900
gene id: 2249356:HYN86_RS01900
uniprot id: A0A344LND1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

2249356:HYN86 RS04600
gene id: 2249356:HYN86_RS04600
uniprot id: A0A344LPS9
names: Similarity
messages: Belongs to the LacAB/RpiB family.

2249356:HYN86 RS06855
gene id: 2249356:HYN86_RS06855
uniprot id: A0A344LQZ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

2249356:HYN86 RS14980
gene id: 2249356:HYN86_RS14980
uniprot id: A0A344LV86
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

2249356:HYN86 RS02545
gene id: 2249356:HYN86_RS02545
uniprot id: A0A344LNP5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Membrane

2249356:HYN86 RS04570
gene id: 2249356:HYN86_RS04570
uniprot id: A0A344LPS3
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

2249356:HYN86 RS03770
gene id: 2249356:HYN86_RS03770
uniprot id: A0A344LPC3
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

2249356:HYN86 RS15795
gene id: 2249356:HYN86_RS15795
uniprot id: A0A344LVN2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

2249356:HYN86 RS00135
gene id: 2249356:HYN86_RS00135
uniprot id: A0A344LMF9
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

2249356:HYN86 RS05665
gene id: 2249356:HYN86_RS05665
uniprot id: A0A344LQC0
names: Subcellular Location Annotation
messages: Cytoplasm

2249356:HYN86 RS05995
gene id: 2249356:HYN86_RS05995
uniprot id: A0A344LYI8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2249356:HYN86 RS07740
gene id: 2249356:HYN86_RS07740
uniprot id: A0A344LRG0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

2249356:HYN86 RS02590
gene id: 2249356:HYN86_RS02590
uniprot id: A0A344LNQ3
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FBPase class 1 family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2249356:HYN86 RS01945
gene id: 2249356:HYN86_RS01945
uniprot id: A0A344LNE0
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

2249356:HYN86 RS00245
gene id: 2249356:HYN86_RS00245
uniprot id: A0A344LYC4
names: Similarity
messages: Belongs to the HSP15 family.

2249356:HYN86 RS00345
gene id: 2249356:HYN86_RS00345
uniprot id: A0A344LMJ3
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

2249356:HYN86 RS01905
gene id: 2249356:HYN86_RS01905
uniprot id: A0A344LND2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

2249356:HYN86 RS08625
gene id: 2249356:HYN86_RS08625
uniprot id: A0A344LRW8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Membrane

2249356:HYN86 RS01970
gene id: 2249356:HYN86_RS01970
uniprot id: A0A344LNE5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

2249356:HYN86 RS02990
gene id: 2249356:HYN86_RS02990
uniprot id: A0A344LNY1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

2249356:HYN86 RS10230
gene id: 2249356:HYN86_RS10230
uniprot id: A0A344LYN2
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

2249356:HYN86 RS09280
gene id: 2249356:HYN86_RS09280
uniprot id: A0A344LS86
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

2249356:HYN86 RS02425
gene id: 2249356:HYN86_RS02425
uniprot id: A0A344LNM4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

2249356:HYN86 RS09305
gene id: 2249356:HYN86_RS09305
uniprot id: A0A344LS91
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

2249356:HYN86 RS11925
gene id: 2249356:HYN86_RS11925
uniprot id: A0A344LTL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

2249356:HYN86 RS01895
gene id: 2249356:HYN86_RS01895
uniprot id: A0A344LYE3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

2249356:HYN86 RS18910
gene id: 2249356:HYN86_RS18910
uniprot id: A0A344LX99
names: Similarity
messages: Belongs to the peptidase C40 family.

2249356:HYN86 RS15230
gene id: 2249356:HYN86_RS15230
uniprot id: A0A344LVD2
names: Similarity
messages: Belongs to the deoxyhypusine synthase family.

2249356:HYN86 RS04625
gene id: 2249356:HYN86_RS04625
uniprot id: A0A344LPT3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Forms a complex with TatC.
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.

2249356:HYN86 RS01840
gene id: 2249356:HYN86_RS01840
uniprot id: A0A344LNC0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

2249356:HYN86 RS20870
gene id: 2249356:HYN86_RS20870
uniprot id: A0A344LYB3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

2249356:HYN86 RS01985
gene id: 2249356:HYN86_RS01985
uniprot id: A0A344LNE8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

2249356:HYN86 RS09290
gene id: 2249356:HYN86_RS09290
uniprot id: A0A344LS88
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.