2249302:F0R75 RS03875
gene id: 2249302:F0R75_RS03875
uniprot id: A0A5C2C1W5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

2249302:F0R75 RS07745
gene id: 2249302:F0R75_RS07745
uniprot id: A0A5C2C4P7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

2249302:F0R75 RS07305
gene id: 2249302:F0R75_RS07305
uniprot id: A0A5C2C1C6
names: Similarity
messages: Belongs to the FBPase class 2 family.

2249302:F0R75 RS09645
gene id: 2249302:F0R75_RS09645
uniprot id: A0A5C2BZ24
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

2249302:F0R75 RS07690
gene id: 2249302:F0R75_RS07690
uniprot id: A0A5C2C4N4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

2249302:F0R75 RS06730
gene id: 2249302:F0R75_RS06730
uniprot id: A0A5C2C3C5
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

2249302:F0R75 RS01300
gene id: 2249302:F0R75_RS01300
uniprot id: A0A5C2BX69
names: Similarity
messages: Belongs to the ABC transporter superfamily.

2249302:F0R75 RS05745
gene id: 2249302:F0R75_RS05745
uniprot id: A0A5C2C4U5
names: Subcellular Location Annotation
messages: Membrane

2249302:F0R75 RS05070
gene id: 2249302:F0R75_RS05070
uniprot id: A0A5C2BVJ7
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

2249302:F0R75 RS08380
gene id: 2249302:F0R75_RS08380
uniprot id: A0A5C2C0X0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
messages: Forms an icosahedral capsid composed of 60 subunits, arranged as a dodecamer of pentamers.

2249302:F0R75 RS00895
gene id: 2249302:F0R75_RS00895
uniprot id: A0A5C2BZM3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

2249302:F0R75 RS01665
gene id: 2249302:F0R75_RS01665
uniprot id: A0A5C2C173
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

2249302:F0R75 RS05490
gene id: 2249302:F0R75_RS05490
uniprot id: A0A5C2C385
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

2249302:F0R75 RS09745
gene id: 2249302:F0R75_RS09745
uniprot id: A0A5C2BZ09
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

2249302:F0R75 RS06215
gene id: 2249302:F0R75_RS06215
uniprot id: A0A5C2C533
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

2249302:F0R75 RS06180
gene id: 2249302:F0R75_RS06180
uniprot id: A0A5C2C3Y7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2249302:F0R75 RS05360
gene id: 2249302:F0R75_RS05360
uniprot id: A0A5C2C314
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

2249302:F0R75 RS09680
gene id: 2249302:F0R75_RS09680
uniprot id: A0A5C2BZ43
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

2249302:F0R75 RS10075
gene id: 2249302:F0R75_RS10075
uniprot id: A0A5C2C5D2
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

2249302:F0R75 RS05780
gene id: 2249302:F0R75_RS05780
uniprot id: A0A5C2BVS6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

2249302:F0R75 RS00225
gene id: 2249302:F0R75_RS00225
uniprot id: A0A5C2C027
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

2249302:F0R75 RS07740
gene id: 2249302:F0R75_RS07740
uniprot id: A0A5C2C0M1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

2249302:F0R75 RS04950
gene id: 2249302:F0R75_RS04950
uniprot id: A0A5C2BWZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

2249302:F0R75 RS09320
gene id: 2249302:F0R75_RS09320
uniprot id: A0A5C2C573
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaD Na(+)/H(+) (TC 2.A.62) antiporter family.
messages: Membrane

2249302:F0R75 RS09740
gene id: 2249302:F0R75_RS09740
uniprot id: A0A5C2BZH3
names: Similarity
messages: Belongs to the glutaredoxin family. Monothiol subfamily.

2249302:F0R75 RS07725
gene id: 2249302:F0R75_RS07725
uniprot id: A0A5C2C0Y3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

2249302:F0R75 RS07730
gene id: 2249302:F0R75_RS07730
uniprot id: A0A5C2C053
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

2249302:F0R75 RS04410
gene id: 2249302:F0R75_RS04410
uniprot id: A0A5C2BWE2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

2249302:F0R75 RS10055
gene id: 2249302:F0R75_RS10055
uniprot id: A0A5C2BY49
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

2249302:F0R75 RS04200
gene id: 2249302:F0R75_RS04200
uniprot id: A0A5C2BVT6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

2249302:F0R75 RS04710
gene id: 2249302:F0R75_RS04710
uniprot id: A0A5C2BVJ5
names: Subcellular Location Annotation
messages: Membrane

2249302:F0R75 RS02330
gene id: 2249302:F0R75_RS02330
uniprot id: A0A5C2C270
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

2249302:F0R75 RS06530
gene id: 2249302:F0R75_RS06530
uniprot id: A0A5C2BUQ6
names: Subcellular Location Annotation
messages: Membrane

2249302:F0R75 RS09705
gene id: 2249302:F0R75_RS09705
uniprot id: A0A5C2C091
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

2249302:F0R75 RS08320
gene id: 2249302:F0R75_RS08320
uniprot id: A0A5C2C521
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

2249302:F0R75 RS07670
gene id: 2249302:F0R75_RS07670
uniprot id: A0A5C2BZD4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

2249302:F0R75 RS01760
gene id: 2249302:F0R75_RS01760
uniprot id: A0A5C2BXX4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

2249302:F0R75 RS04325
gene id: 2249302:F0R75_RS04325
uniprot id: A0A5C2C441
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

2249302:F0R75 RS07025
gene id: 2249302:F0R75_RS07025
uniprot id: A0A5C2C4Z4
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

2249302:F0R75 RS00765
gene id: 2249302:F0R75_RS00765
uniprot id: A0A5C2C0A7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecB family.
messages: Cytoplasm
messages: Homotetramer, a dimer of dimers. One homotetramer interacts with 1 SecA dimer.
messages: One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.

2249302:F0R75 RS05785
gene id: 2249302:F0R75_RS05785
uniprot id: A0A5C2C501
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uridine kinase family.
messages: Cytoplasm

2249302:F0R75 RS01295
gene id: 2249302:F0R75_RS01295
uniprot id: A0A5C2BY82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

2249302:F0R75 RS06100
gene id: 2249302:F0R75_RS06100
uniprot id: A0A5C2BVL4
names: Function
names: Similarity
messages: Belongs to the Fe(2+)-trafficking protein family.
messages: Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.

2249302:F0R75 RS07660
gene id: 2249302:F0R75_RS07660
uniprot id: A0A5C2BZM1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

2249302:F0R75 RS09950
gene id: 2249302:F0R75_RS09950
uniprot id: A0A5C2BY54
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphopentomutase family.
messages: Binds 1 or 2 manganese ions.
messages: Cytoplasm
messages: Phosphotransfer between the C1 and C5 carbon atoms of pentose.

2249302:F0R75 RS01790
gene id: 2249302:F0R75_RS01790
uniprot id: A0A5C2BX56
names: Similarity
messages: Belongs to the pyruvate kinase family.

2249302:F0R75 RS07135
gene id: 2249302:F0R75_RS07135
uniprot id: A0A5C2BVY0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MinC family.
messages: Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization.
messages: Interacts with MinD and FtsZ.

2249302:F0R75 RS07680
gene id: 2249302:F0R75_RS07680
uniprot id: A0A5C2C612
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

2249302:F0R75 RS05875
gene id: 2249302:F0R75_RS05875
uniprot id: A0A5C2BUV5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

2249302:F0R75 RS02575
gene id: 2249302:F0R75_RS02575
uniprot id: A0A5C2BXL3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

2249302:F0R75 RS06560
gene id: 2249302:F0R75_RS06560
uniprot id: A0A5C2BWR9
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).

2249302:F0R75 RS06430
gene id: 2249302:F0R75_RS06430
uniprot id: A0A5C2C3R8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

2249302:F0R75 RS07125
gene id: 2249302:F0R75_RS07125
uniprot id: A0A5C2C511
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

2249302:F0R75 RS01215
gene id: 2249302:F0R75_RS01215
uniprot id: A0A5C2BXL4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

2249302:F0R75 RS07145
gene id: 2249302:F0R75_RS07145
uniprot id: A0A5C2BVX6
names: Function
names: Similarity
messages: Belongs to the MinE family.
messages: Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.

2249302:F0R75 RS07665
gene id: 2249302:F0R75_RS07665
uniprot id: A0A5C2C190
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

2249302:F0R75 RS05055
gene id: 2249302:F0R75_RS05055
uniprot id: A0A5C2BWX5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

2249302:F0R75 RS04735
gene id: 2249302:F0R75_RS04735
uniprot id: A0A5C2C378
names: Subcellular Location Annotation
messages: Cytoplasm

2249302:F0R75 RS01335
gene id: 2249302:F0R75_RS01335
uniprot id: A0A5C2BZD2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2249302:F0R75 RS07720
gene id: 2249302:F0R75_RS07720
uniprot id: A0A5C2BZC3
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: Methylated by PrmB.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

2249302:F0R75 RS06425
gene id: 2249302:F0R75_RS06425
uniprot id: A0A5C2BWT4
names: Subcellular Location Annotation
messages: Cytoplasm

2249302:F0R75 RS02015
gene id: 2249302:F0R75_RS02015
uniprot id: A0A5C2C0Z1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

2249302:F0R75 RS07010
gene id: 2249302:F0R75_RS07010
uniprot id: A0A5C2BV42
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbD/TolR family.
messages: Cell inner membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

2249302:F0R75 RS00015
gene id: 2249302:F0R75_RS00015
uniprot id: A0A5C2BZY6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

2249302:F0R75 RS08335
gene id: 2249302:F0R75_RS08335
uniprot id: A0A5C2C080
names: Similarity
messages: Belongs to the Skp family.

2249302:F0R75 RS09720
gene id: 2249302:F0R75_RS09720
uniprot id: A0A5C2C082
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

2249302:F0R75 RS04315
gene id: 2249302:F0R75_RS04315
uniprot id: A0A5C2BX29
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

2249302:F0R75 RS00885
gene id: 2249302:F0R75_RS00885
uniprot id: A0A5C2BYC2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamA family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

2249302:F0R75 RS07490
gene id: 2249302:F0R75_RS07490
uniprot id: A0A5C2C1H5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

2249302:F0R75 RS07015
gene id: 2249302:F0R75_RS07015
uniprot id: A0A5C2C4A7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

2249302:F0R75 RS07760
gene id: 2249302:F0R75_RS07760
uniprot id: A0A5C2C0I4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di-trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2249302:F0R75 RS00605
gene id: 2249302:F0R75_RS00605
uniprot id: A0A5C2C244
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

2249302:F0R75 RS07130
gene id: 2249302:F0R75_RS07130
uniprot id: A0A5C2BWG4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

2249302:F0R75 RS07175
gene id: 2249302:F0R75_RS07175
uniprot id: A0A5C2BVL0
names: Similarity
messages: Belongs to the BolA/IbaG family.

2249302:F0R75 RS01765
gene id: 2249302:F0R75_RS01765
uniprot id: A0A5C2C1Y5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

2249302:F0R75 RS09730
gene id: 2249302:F0R75_RS09730
uniprot id: A0A5C2BZ33
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

2249302:F0R75 RS04560
gene id: 2249302:F0R75_RS04560
uniprot id: A0A5C2C454
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

2249302:F0R75 RS05415
gene id: 2249302:F0R75_RS05415
uniprot id: A0A5C2C325
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

2249302:F0R75 RS07695
gene id: 2249302:F0R75_RS07695
uniprot id: A0A5C2C5V3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

2249302:F0R75 RS09695
gene id: 2249302:F0R75_RS09695
uniprot id: A0A5C2BZ16
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

2249302:F0R75 RS00065
gene id: 2249302:F0R75_RS00065
uniprot id: A0A5C2BZZ6
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

2249302:F0R75 RS06065
gene id: 2249302:F0R75_RS06065
uniprot id: A0A5C2C504
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide.

2249302:F0R75 RS05795
gene id: 2249302:F0R75_RS05795
uniprot id: A0A5C2C3R7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HesB/IscA family.
messages: Binds 1 iron-sulfur cluster per subunit.
messages: Homodimer.
messages: Required for insertion of 4Fe-4S clusters for at least IspG.

2249302:F0R75 RS07710
gene id: 2249302:F0R75_RS07710
uniprot id: A0A5C2C4Y0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

2249302:F0R75 RS09545
gene id: 2249302:F0R75_RS09545
uniprot id: A0A5C2C5A8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

2249302:F0R75 RS01395
gene id: 2249302:F0R75_RS01395
uniprot id: A0A5C2BXC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

2249302:F0R75 RS05365
gene id: 2249302:F0R75_RS05365
uniprot id: A0A5C2BVL3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

2249302:F0R75 RS08655
gene id: 2249302:F0R75_RS08655
uniprot id: A0A5C2C5N4
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.

2249302:F0R75 RS03810
gene id: 2249302:F0R75_RS03810
uniprot id: A0A5C2BXI6
names: Subcellular Location Annotation
messages: Membrane

2249302:F0R75 RS02010
gene id: 2249302:F0R75_RS02010
uniprot id: A0A5C2C1W9
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

2249302:F0R75 RS03010
gene id: 2249302:F0R75_RS03010
uniprot id: A0A5C2BXP9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

2249302:F0R75 RS05880
gene id: 2249302:F0R75_RS05880
uniprot id: A0A5C2C2W6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

2249302:F0R75 RS06295
gene id: 2249302:F0R75_RS06295
uniprot id: A0A5C2BVI2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

2249302:F0R75 RS08030
gene id: 2249302:F0R75_RS08030
uniprot id: A0A5C2BZF5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the calycin superfamily. Lipocalin family.
messages: Cell outer membrane
messages: Homodimer.
messages: Involved in the storage or transport of lipids necessary for membrane maintenance under stressful conditions. Displays a binding preference for lysophospholipids.

2249302:F0R75 RS05790
gene id: 2249302:F0R75_RS05790
uniprot id: A0A5C2BWB2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

2249302:F0R75 RS06930
gene id: 2249302:F0R75_RS06930
uniprot id: A0A5C2BW11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0382 family.
messages: Membrane

2249302:F0R75 RS07620
gene id: 2249302:F0R75_RS07620
uniprot id: A0A5C2C524
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

2249302:F0R75 RS01740
gene id: 2249302:F0R75_RS01740
uniprot id: A0A5C2BX68
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

2249302:F0R75 RS03730
gene id: 2249302:F0R75_RS03730
uniprot id: A0A5C2BX18
names: Similarity
messages: Belongs to the site-specific recombinase resolvase family.

2249302:F0R75 RS03890
gene id: 2249302:F0R75_RS03890
uniprot id: A0A5C2C3W2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

2249302:F0R75 RS07450
gene id: 2249302:F0R75_RS07450
uniprot id: A0A5C2C1C0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell inner membrane
messages: Membrane

2249302:F0R75 RS02820
gene id: 2249302:F0R75_RS02820
uniprot id: A0A5C2C2G1
names: Similarity
messages: Belongs to the ribosome association toxin RatA family.

2249302:F0R75 RS08790
gene id: 2249302:F0R75_RS08790
uniprot id: A0A5C2BZU7
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

2249302:F0R75 RS02580
gene id: 2249302:F0R75_RS02580
uniprot id: A0A5C2C246
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

2249302:F0R75 RS05895
gene id: 2249302:F0R75_RS05895
uniprot id: A0A5C2C3A7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

2249302:F0R75 RS07685
gene id: 2249302:F0R75_RS07685
uniprot id: A0A5C2C0N1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

2249302:F0R75 RS02875
gene id: 2249302:F0R75_RS02875
uniprot id: A0A5C2C2H1
names: Cofactor
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Binds 1 Fe(3+) ion per subunit.

2249302:F0R75 RS04855
gene id: 2249302:F0R75_RS04855
uniprot id: A0A5C2BVX1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

2249302:F0R75 RS00925
gene id: 2249302:F0R75_RS00925
uniprot id: A0A5C2BYE5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.
messages: Homotetramer.
messages: Uses inorganic polyphosphate (polyP) as a donor to convert GDP to GTP or ADP to ATP.

2249302:F0R75 RS08400
gene id: 2249302:F0R75_RS08400
uniprot id: A0A5C2C5I1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

2249302:F0R75 RS00010
gene id: 2249302:F0R75_RS00010
uniprot id: A0A5C2C100
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

2249302:F0R75 RS09500
gene id: 2249302:F0R75_RS09500
uniprot id: A0A5C2BZQ4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

2249302:F0R75 RS00915
gene id: 2249302:F0R75_RS00915
uniprot id: A0A5C2C1D6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZipA family.
messages: Cell inner membrane
messages: Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins.

2249302:F0R75 RS00910
gene id: 2249302:F0R75_RS00910
uniprot id: A0A5C2C0T3
names: Function
names: Similarity
messages: Belongs to the LpxB family.
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

2249302:F0R75 RS08565
gene id: 2249302:F0R75_RS08565
uniprot id: A0A5C2BYV2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

2249302:F0R75 RS09510
gene id: 2249302:F0R75_RS09510
uniprot id: A0A5C2C626
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

2249302:F0R75 RS07630
gene id: 2249302:F0R75_RS07630
uniprot id: A0A5C2C601
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

2249302:F0R75 RS03985
gene id: 2249302:F0R75_RS03985
uniprot id: A0A5C2C1X9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Catalyzes the deamination of dCTP to dUTP.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2249302:F0R75 RS00760
gene id: 2249302:F0R75_RS00760
uniprot id: A0A5C2BXN5
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

2249302:F0R75 RS04780
gene id: 2249302:F0R75_RS04780
uniprot id: A0A5C2C2Q6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

2249302:F0R75 RS05245
gene id: 2249302:F0R75_RS05245
uniprot id: A0A5C2BWL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

2249302:F0R75 RS01340
gene id: 2249302:F0R75_RS01340
uniprot id: A0A5C2BXD5
names: Similarity
messages: Belongs to the thioredoxin family.

2249302:F0R75 RS02140
gene id: 2249302:F0R75_RS02140
uniprot id: A0A5C2BWT1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2249302:F0R75 RS05505
gene id: 2249302:F0R75_RS05505
uniprot id: A0A5C2BVX8
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

2249302:F0R75 RS03255
gene id: 2249302:F0R75_RS03255
uniprot id: A0A5C2BW88
names: Similarity
messages: Belongs to the YjdM family.

2249302:F0R75 RS03275
gene id: 2249302:F0R75_RS03275
uniprot id: A0A5C2BX57
names: Function
names: Subunit
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease.

2249302:F0R75 RS07590
gene id: 2249302:F0R75_RS07590
uniprot id: A0A5C2C014
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

2249302:F0R75 RS08315
gene id: 2249302:F0R75_RS08315
uniprot id: A0A5C2C0B9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

2249302:F0R75 RS08325
gene id: 2249302:F0R75_RS08325
uniprot id: A0A5C2C676
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecB family.
messages: Cytoplasm
messages: Homotetramer, a dimer of dimers. One homotetramer interacts with 1 SecA dimer.
messages: One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.

2249302:F0R75 RS08155
gene id: 2249302:F0R75_RS08155
uniprot id: A0A5C2BZ36
names: Similarity
messages: Belongs to the YggT family.

2249302:F0R75 RS09685
gene id: 2249302:F0R75_RS09685
uniprot id: A0A5C2C570
names: Subcellular Location Annotation
messages: Membrane

2249302:F0R75 RS05805
gene id: 2249302:F0R75_RS05805
uniprot id: A0A5C2C4C7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

2249302:F0R75 RS07610
gene id: 2249302:F0R75_RS07610
uniprot id: A0A5C2C4V9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

2249302:F0R75 RS03055
gene id: 2249302:F0R75_RS03055
uniprot id: A0A5C2BXD3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

2249302:F0R75 RS04600
gene id: 2249302:F0R75_RS04600
uniprot id: A0A5C2BWL9
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

2249302:F0R75 RS09780
gene id: 2249302:F0R75_RS09780
uniprot id: A0A5C2C702
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

2249302:F0R75 RS03920
gene id: 2249302:F0R75_RS03920
uniprot id: A0A5C2C2V8
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

2249302:F0R75 RS09405
gene id: 2249302:F0R75_RS09405
uniprot id: A0A5C2C610
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

2249302:F0R75 RS07780
gene id: 2249302:F0R75_RS07780
uniprot id: A0A5C2C044
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

2249302:F0R75 RS04320
gene id: 2249302:F0R75_RS04320
uniprot id: A0A5C2BXY8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

2249302:F0R75 RS01000
gene id: 2249302:F0R75_RS01000
uniprot id: A0A5C2BYQ6
names: Similarity
messages: Belongs to the CFA/CMAS family.

2249302:F0R75 RS09540
gene id: 2249302:F0R75_RS09540
uniprot id: A0A5C2BZI8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: Composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

2249302:F0R75 RS07075
gene id: 2249302:F0R75_RS07075
uniprot id: A0A5C2BWH4
names: Similarity
messages: Belongs to the ArsC family.

2249302:F0R75 RS02510
gene id: 2249302:F0R75_RS02510
uniprot id: A0A5C2BX06
names: Subcellular Location Annotation
messages: Membrane

2249302:F0R75 RS01920
gene id: 2249302:F0R75_RS01920
uniprot id: A0A5C2C2U4
names: Subcellular Location Annotation
messages: Membrane

2249302:F0R75 RS05345
gene id: 2249302:F0R75_RS05345
uniprot id: A0A5C2C3Q2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2249302:F0R75 RS00005
gene id: 2249302:F0R75_RS00005
uniprot id: A0A5C2BYU9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

2249302:F0R75 RS02130
gene id: 2249302:F0R75_RS02130
uniprot id: A0A5C2BWZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamD family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

2249302:F0R75 RS06750
gene id: 2249302:F0R75_RS06750
uniprot id: A0A5C2BV88
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2249302:F0R75 RS03760
gene id: 2249302:F0R75_RS03760
uniprot id: A0A5C2C1U6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

2249302:F0R75 RS04795
gene id: 2249302:F0R75_RS04795
uniprot id: A0A5C2C383
names: Similarity
messages: Belongs to the peptidase T1B family. HslV subfamily.

2249302:F0R75 RS08600
gene id: 2249302:F0R75_RS08600
uniprot id: A0A5C2C0S7
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome. Modification of Lys-34 is required for alleviation.
messages: May be beta-lysylated on the epsilon-amino group of Lys-34 by the combined action of EpmA and EpmB, and then hydroxylated on the C5 position of the same residue by EpmC (if this protein is present). Lysylation is critical for the stimulatory effect of EF-P on peptide-bond formation. The lysylation moiety may extend toward the peptidyltransferase center and stabilize the terminal 3-CCA end of the tRNA. Hydroxylation of the C5 position on Lys-34 may allow additional potential stabilizing hydrogen-bond interactions with the P-tRNA.

2249302:F0R75 RS07675
gene id: 2249302:F0R75_RS07675
uniprot id: A0A5C2C3X2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

2249302:F0R75 RS09760
gene id: 2249302:F0R75_RS09760
uniprot id: A0A5C2BZK7
names: Similarity
messages: Belongs to the citrate synthase family.

2249302:F0R75 RS02535
gene id: 2249302:F0R75_RS02535
uniprot id: A0A5C2C374
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

2249302:F0R75 RS04240
gene id: 2249302:F0R75_RS04240
uniprot id: A0A5C2BW01
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

2249302:F0R75 RS04800
gene id: 2249302:F0R75_RS04800
uniprot id: A0A5C2BVY1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
messages: Belongs to the ClpX chaperone family. HslU subfamily.
messages: Cytoplasm

2249302:F0R75 RS02220
gene id: 2249302:F0R75_RS02220
uniprot id: A0A5C2C128
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

2249302:F0R75 RS00675
gene id: 2249302:F0R75_RS00675
uniprot id: A0A5C2C6Q2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Membrane

2249302:F0R75 RS05800
gene id: 2249302:F0R75_RS05800
uniprot id: A0A5C2BWL2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

2249302:F0R75 RS07550
gene id: 2249302:F0R75_RS07550
uniprot id: A0A5C2C4A0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

2249302:F0R75 RS05445
gene id: 2249302:F0R75_RS05445
uniprot id: A0A5C2BVY9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptF/LptG family.
messages: Cell inner membrane
messages: Component of the lipopolysaccharide transport and assembly complex. The LptBFG transporter is composed of two ATP-binding proteins (LptB) and two transmembrane proteins (LptF and LptG).
messages: Membrane
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane.

2249302:F0R75 RS05085
gene id: 2249302:F0R75_RS05085
uniprot id: A0A5C2BW57
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

2249302:F0R75 RS09700
gene id: 2249302:F0R75_RS09700
uniprot id: A0A5C2BZF7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

2249302:F0R75 RS03915
gene id: 2249302:F0R75_RS03915
uniprot id: A0A5C2C2E8
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

2249302:F0R75 RS03245
gene id: 2249302:F0R75_RS03245
uniprot id: A0A5C2C1L1
names: Similarity
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.

2249302:F0R75 RS09865
gene id: 2249302:F0R75_RS09865
uniprot id: A0A5C2BZI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

2249302:F0R75 RS07655
gene id: 2249302:F0R75_RS07655
uniprot id: A0A5C2C4B9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

2249302:F0R75 RS06850
gene id: 2249302:F0R75_RS06850
uniprot id: A0A5C2C3T9
names: Subcellular Location Annotation
messages: Membrane

2249302:F0R75 RS07615
gene id: 2249302:F0R75_RS07615
uniprot id: A0A5C2C3W0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

2249302:F0R75 RS05735
gene id: 2249302:F0R75_RS05735
uniprot id: A0A5C2C382
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsB family.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

2249302:F0R75 RS07735
gene id: 2249302:F0R75_RS07735
uniprot id: A0A5C2C622
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

2249302:F0R75 RS06120
gene id: 2249302:F0R75_RS06120
uniprot id: A0A5C2C4I5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Cytoplasm
messages: Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

2249302:F0R75 RS02355
gene id: 2249302:F0R75_RS02355
uniprot id: A0A5C2BXR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

2249302:F0R75 RS07700
gene id: 2249302:F0R75_RS07700
uniprot id: A0A5C2C194
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

2249302:F0R75 RS04225
gene id: 2249302:F0R75_RS04225
uniprot id: A0A5C2C426
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

2249302:F0R75 RS02325
gene id: 2249302:F0R75_RS02325
uniprot id: A0A5C2C147
names: Similarity
messages: Belongs to the LOG family.

2249302:F0R75 RS06025
gene id: 2249302:F0R75_RS06025
uniprot id: A0A5C2BWP4
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

2249302:F0R75 RS04910
gene id: 2249302:F0R75_RS04910
uniprot id: A0A5C2BXM8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

2249302:F0R75 RS00050
gene id: 2249302:F0R75_RS00050
uniprot id: A0A5C2C103
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

2249302:F0R75 RS02065
gene id: 2249302:F0R75_RS02065
uniprot id: A0A5C2BYE1
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

2249302:F0R75 RS07640
gene id: 2249302:F0R75_RS07640
uniprot id: A0A5C2C002
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

2249302:F0R75 RS04930
gene id: 2249302:F0R75_RS04930
uniprot id: A0A5C2BW84
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RuvC family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.

2249302:F0R75 RS04245
gene id: 2249302:F0R75_RS04245
uniprot id: A0A5C2C212
names: Similarity
messages: Belongs to the peptidase S13 family.

2249302:F0R75 RS05215
gene id: 2249302:F0R75_RS05215
uniprot id: A0A5C2C4K2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).

2249302:F0R75 RS08085
gene id: 2249302:F0R75_RS08085
uniprot id: A0A5C2C110
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

2249302:F0R75 RS09535
gene id: 2249302:F0R75_RS09535
uniprot id: A0A5C2C6R6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

2249302:F0R75 RS07185
gene id: 2249302:F0R75_RS07185
uniprot id: A0A5C2BVX0
names: Similarity
messages: Belongs to the MlaA family.

2249302:F0R75 RS03740
gene id: 2249302:F0R75_RS03740
uniprot id: A0A5C2BXC3
names: Similarity
messages: Belongs to the FrmR/RcnR family.

2249302:F0R75 RS02085
gene id: 2249302:F0R75_RS02085
uniprot id: A0A5C2BXV0
names: Subcellular Location Annotation
messages: Membrane

2249302:F0R75 RS07605
gene id: 2249302:F0R75_RS07605
uniprot id: A0A5C2C4A8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

2249302:F0R75 RS09090
gene id: 2249302:F0R75_RS09090
uniprot id: A0A5C2C535
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

2249302:F0R75 RS04305
gene id: 2249302:F0R75_RS04305
uniprot id: A0A5C2BWK5
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.

2249302:F0R75 RS09975
gene id: 2249302:F0R75_RS09975
uniprot id: A0A5C2BZG8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

2249302:F0R75 RS10070
gene id: 2249302:F0R75_RS10070
uniprot id: A0A5C2BY36
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

2249302:F0R75 RS05815
gene id: 2249302:F0R75_RS05815
uniprot id: A0A5C2BV50
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsL family.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
messages: Membrane
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

2249302:F0R75 RS02235
gene id: 2249302:F0R75_RS02235
uniprot id: A0A5C2BWX8
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

2249302:F0R75 RS09905
gene id: 2249302:F0R75_RS09905
uniprot id: A0A5C2BYY0
names: Subcellular Location Annotation
messages: Membrane

2249302:F0R75 RS00900
gene id: 2249302:F0R75_RS00900
uniprot id: A0A5C2BYZ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

2249302:F0R75 RS05100
gene id: 2249302:F0R75_RS05100
uniprot id: A0A5C2BXI0
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

2249302:F0R75 RS04180
gene id: 2249302:F0R75_RS04180
uniprot id: A0A5C2BW79
names: Function
names: Similarity
messages: Belongs to the ABC transporter superfamily. Outer membrane lipopolysaccharide export (TC 1.B.42) family.
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane. Probably responsible for energy coupling to the transport system.

2249302:F0R75 RS03960
gene id: 2249302:F0R75_RS03960
uniprot id: A0A5C2BY47
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

2249302:F0R75 RS07635
gene id: 2249302:F0R75_RS07635
uniprot id: A0A5C2C0P1
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

2249302:F0R75 RS07155
gene id: 2249302:F0R75_RS07155
uniprot id: A0A5C2BV26
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MlaE permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the ABC transporter complex MlaFEDB, which is involved in a phospholipid transport pathway that maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (MlaF), two transmembrane proteins (MlaE), two cytoplasmic solute-binding proteins (MlaB) and six periplasmic solute-binding proteins (MlaD).