223919:F3K33 RS20900
gene id: 223919:F3K33_RS20900
uniprot id: A0A5P2EYK2
names: Function
names: Similarity
messages: Belongs to the mannonate dehydratase family.
messages: Catalyzes the dehydration of D-mannonate.

223919:F3K33 RS12070
gene id: 223919:F3K33_RS12070
uniprot id: A0A5P2EXZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

223919:F3K33 RS23255
gene id: 223919:F3K33_RS23255
uniprot id: A0A5P2EZT8
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
messages: Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

223919:F3K33 RS24460
gene id: 223919:F3K33_RS24460
uniprot id: A0A5P2F0G2
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

223919:F3K33 RS05835
gene id: 223919:F3K33_RS05835
uniprot id: A0A5P2ER04
names: Similarity
messages: Belongs to the glycosyl hydrolase 25 family.

223919:F3K33 RS18955
gene id: 223919:F3K33_RS18955
uniprot id: A0A5P2F8F9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CbiN family.
messages: Cell membrane
messages: Forms an energy-coupling factor (ECF) transporter complex composed of an ATP-binding protein (A component, CbiO), a transmembrane protein (T component, CbiQ) and 2 possible substrate-capture proteins (S components, CbiM and CbiN) of unknown stoichimetry.
messages: Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import.

223919:F3K33 RS00595
gene id: 223919:F3K33_RS00595
uniprot id: A0A5P2ERV0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

223919:F3K33 RS08610
gene id: 223919:F3K33_RS08610
uniprot id: A0A5P2EY16
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.

223919:F3K33 RS13130
gene id: 223919:F3K33_RS13130
uniprot id: A0A5P2EUG5
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

223919:F3K33 RS08905
gene id: 223919:F3K33_RS08905
uniprot id: A0A5P2ESL3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

223919:F3K33 RS05325
gene id: 223919:F3K33_RS05325
uniprot id: A0A5P2ESV5
names: Caution
names: Function
names: Similarity
messages: Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor.
messages: Belongs to the biotin--protein ligase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

223919:F3K33 RS22170
gene id: 223919:F3K33_RS22170
uniprot id: A0A5P2FAD7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

223919:F3K33 RS09100
gene id: 223919:F3K33_RS09100
uniprot id: A0A5P2ESM5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

223919:F3K33 RS25390
gene id: 223919:F3K33_RS25390
uniprot id: A0A5P2FC02
names: Similarity
messages: Belongs to the P(II) protein family.

223919:F3K33 RS08260
gene id: 223919:F3K33_RS08260
uniprot id: A0A5P2ES67
names: Similarity
messages: Belongs to the MotB family.

223919:F3K33 RS02485
gene id: 223919:F3K33_RS02485
uniprot id: A0A5P2EPD9
names: Function
names: Similarity
messages: Belongs to the RecD family. RecD-like subfamily.
messages: DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity.

223919:F3K33 RS24880
gene id: 223919:F3K33_RS24880
uniprot id: A0A5P2F107
names: Function
names: Similarity
messages: Belongs to the 'phage' integrase family.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.

223919:F3K33 RS03630
gene id: 223919:F3K33_RS03630
uniprot id: A0A5P2EPR7
names: Similarity
messages: Belongs to the RNase H family.

223919:F3K33 RS15150
gene id: 223919:F3K33_RS15150
uniprot id: A0A5P2EVT0
names: Similarity
messages: Belongs to the peptidase C40 family.

223919:F3K33 RS21675
gene id: 223919:F3K33_RS21675
uniprot id: A0A5P2EYP1
names: Similarity
messages: Belongs to the acylphosphatase family.

223919:F3K33 RS21115
gene id: 223919:F3K33_RS21115
uniprot id: A0A5P2EYH2
names: Similarity
messages: Belongs to the DapA family.

223919:F3K33 RS21325
gene id: 223919:F3K33_RS21325
uniprot id: A0A5P2F283
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

223919:F3K33 RS07825
gene id: 223919:F3K33_RS07825
uniprot id: A0A5P2EUJ0
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

223919:F3K33 RS15465
gene id: 223919:F3K33_RS15465
uniprot id: A0A5P2EYG5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

223919:F3K33 RS22600
gene id: 223919:F3K33_RS22600
uniprot id: A0A5P2F3P8
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-I family.

223919:F3K33 RS04240
gene id: 223919:F3K33_RS04240
uniprot id: A0A5P2ESL8
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

223919:F3K33 RS19335
gene id: 223919:F3K33_RS19335
uniprot id: A0A5P2EXG8
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

223919:F3K33 RS15660
gene id: 223919:F3K33_RS15660
uniprot id: A0A5P2EZV7
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

223919:F3K33 RS24555
gene id: 223919:F3K33_RS24555
uniprot id: A0A5P2F062
names: Similarity
messages: Belongs to the 4-oxalocrotonate tautomerase family.

223919:F3K33 RS25120
gene id: 223919:F3K33_RS25120
uniprot id: A0A5P2F514
names: Similarity
messages: Belongs to the CinA family.

223919:F3K33 RS05380
gene id: 223919:F3K33_RS05380
uniprot id: A0A5P2EQS7
names: Subcellular Location Annotation
messages: Membrane

223919:F3K33 RS12325
gene id: 223919:F3K33_RS12325
uniprot id: A0A5P2EXR1
names: Function
names: Similarity
messages: Belongs to the flavodoxin family.
messages: Low-potential electron donor to a number of redox enzymes.

223919:F3K33 RS09635
gene id: 223919:F3K33_RS09635
uniprot id: A0A5P2ESZ0
names: PTM
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.
messages: Carbamylation allows a single lysine to coordinate two divalent metal cations.

223919:F3K33 RS25010
gene id: 223919:F3K33_RS25010
uniprot id: A0A5P2FBU6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

223919:F3K33 RS10995
gene id: 223919:F3K33_RS10995
uniprot id: A0A5P2ETK4
names: Cofactor
names: Similarity
messages: Belongs to the iron-containing alcohol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.

223919:F3K33 RS09535
gene id: 223919:F3K33_RS09535
uniprot id: A0A5P2ESU7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

223919:F3K33 RS18480
gene id: 223919:F3K33_RS18480
uniprot id: A0A5P2F3G7
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

223919:F3K33 RS12185
gene id: 223919:F3K33_RS12185
uniprot id: A0A5P2F553
names: Subcellular Location Annotation
messages: Membrane

223919:F3K33 RS25590
gene id: 223919:F3K33_RS25590
uniprot id: A0A5P2F374
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

223919:F3K33 RS09400
gene id: 223919:F3K33_RS09400
uniprot id: A0A5P2ESL4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

223919:F3K33 RS19860
gene id: 223919:F3K33_RS19860
uniprot id: A0A5P2EY18
names: Cofactor
names: Similarity
messages: Belongs to the iron-containing alcohol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.

223919:F3K33 RS22970
gene id: 223919:F3K33_RS22970
uniprot id: A0A5P2F5W0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).

223919:F3K33 RS13340
gene id: 223919:F3K33_RS13340
uniprot id: A0A5P2EUR1
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

223919:F3K33 RS06250
gene id: 223919:F3K33_RS06250
uniprot id: A0A5P2ETP7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

223919:F3K33 RS03425
gene id: 223919:F3K33_RS03425
uniprot id: A0A5P2EPT8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

223919:F3K33 RS20500
gene id: 223919:F3K33_RS20500
uniprot id: A0A5P2F4I6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetokinase family.
messages: Cytoplasm

223919:F3K33 RS08145
gene id: 223919:F3K33_RS08145
uniprot id: A0A5P2ES50
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

223919:F3K33 RS21365
gene id: 223919:F3K33_RS21365
uniprot id: A0A5P2EYM3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

223919:F3K33 RS22050
gene id: 223919:F3K33_RS22050
uniprot id: A0A5P2EZ12
names: Function
names: Similarity
messages: Belongs to the CheD family.
messages: Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.

223919:F3K33 RS10410
gene id: 223919:F3K33_RS10410
uniprot id: A0A5P2ET43
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TER reductase family.
messages: Involved in the fatty acid synthesis (FAS II). Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to a coenzyme A (CoA).
messages: Monomer.

223919:F3K33 RS08475
gene id: 223919:F3K33_RS08475
uniprot id: A0A5P2ESA3
names: Similarity
messages: Belongs to the hemerythrin family.

223919:F3K33 RS15455
gene id: 223919:F3K33_RS15455
uniprot id: A0A5P2EZR7
names: Subcellular Location Annotation
messages: Membrane

223919:F3K33 RS15085
gene id: 223919:F3K33_RS15085
uniprot id: A0A5P2F1N8
names: Similarity
messages: Belongs to the thioredoxin family.

223919:F3K33 RS14945
gene id: 223919:F3K33_RS14945
uniprot id: A0A5P2EY69
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

223919:F3K33 RS22080
gene id: 223919:F3K33_RS22080
uniprot id: A0A5P2F5F0
names: Similarity
messages: Belongs to the UPF0473 family.

223919:F3K33 RS15375
gene id: 223919:F3K33_RS15375
uniprot id: A0A5P2EVQ8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HCP family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Binds 1 hybrid [4Fe-2O-2S] cluster.
messages: Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
messages: Cytoplasm

223919:F3K33 RS20675
gene id: 223919:F3K33_RS20675
uniprot id: A0A5P2EYN6
names: Similarity
messages: Belongs to the peptidase M29 family.

223919:F3K33 RS01270
gene id: 223919:F3K33_RS01270
uniprot id: A0A5P2ES66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

223919:F3K33 RS20660
gene id: 223919:F3K33_RS20660
uniprot id: A0A5P2F154
names: Function
names: Similarity
names: Subunit
messages: Belongs to the YdjC deacetylase family.
messages: Homodimer.
messages: Probably catalyzes the deacetylation of acetylated carbohydrates an important step in the degradation of oligosaccharides.

223919:F3K33 RS21205
gene id: 223919:F3K33_RS21205
uniprot id: A0A5P2EYY9
names: Similarity
messages: Belongs to the BMP lipoprotein family.

223919:F3K33 RS00980
gene id: 223919:F3K33_RS00980
uniprot id: A0A5P2ENX6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

223919:F3K33 RS05480
gene id: 223919:F3K33_RS05480
uniprot id: A0A5P2EQV8
names: Subcellular Location Annotation
messages: Membrane

223919:F3K33 RS13135
gene id: 223919:F3K33_RS13135
uniprot id: A0A5P2EUM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0014 family.
messages: Membrane

223919:F3K33 RS01265
gene id: 223919:F3K33_RS01265
uniprot id: A0A5P2ES37
names: Similarity
messages: Belongs to the bacterial solute-binding protein 1 family.

223919:F3K33 RS19350
gene id: 223919:F3K33_RS19350
uniprot id: A0A5P2EXK4
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

223919:F3K33 RS17370
gene id: 223919:F3K33_RS17370
uniprot id: A0A5P2F213
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

223919:F3K33 RS21830
gene id: 223919:F3K33_RS21830
uniprot id: A0A5P2EYS6
names: Subcellular Location Annotation
messages: Cytoplasm

223919:F3K33 RS01475
gene id: 223919:F3K33_RS01475
uniprot id: A0A5P2EZM7
names: Subcellular Location Annotation
messages: Membrane

223919:F3K33 RS01050
gene id: 223919:F3K33_RS01050
uniprot id: A0A5P2ERZ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

223919:F3K33 RS22045
gene id: 223919:F3K33_RS22045
uniprot id: A0A5P2EZ73
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

223919:F3K33 RS12405
gene id: 223919:F3K33_RS12405
uniprot id: A0A5P2EU96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

223919:F3K33 RS00110
gene id: 223919:F3K33_RS00110
uniprot id: A0A5P2ENJ3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. AddB/RexB type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster.
messages: Heterodimer of AddA and AddB.
messages: The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddB nuclease domain is not required for chi fragment generation; this subunit has 5' -> 3' nuclease activity.

223919:F3K33 RS07690
gene id: 223919:F3K33_RS07690
uniprot id: A0A5P2EU59
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the flotillin-like FloA family.
messages: Cell membrane
messages: Found in functional membrane microdomains (FMM) that may be equivalent to eukaryotic membrane rafts FMMs are highly dynamic and increase in number as cells age. Flotillins are thought to be important factors in membrane fluidity.
messages: Homooligomerizes.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane raft

223919:F3K33 RS04425
gene id: 223919:F3K33_RS04425
uniprot id: A0A5P2ESB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TspO/BZRP family.
messages: Membrane

223919:F3K33 RS24890
gene id: 223919:F3K33_RS24890
uniprot id: A0A5P2F0J8
names: Similarity
messages: Belongs to the pyruvate kinase family.

223919:F3K33 RS19430
gene id: 223919:F3K33_RS19430
uniprot id: A0A5P2F0I4
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

223919:F3K33 RS19095
gene id: 223919:F3K33_RS19095
uniprot id: A0A5P2F033
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

223919:F3K33 RS21715
gene id: 223919:F3K33_RS21715
uniprot id: A0A5P2FA42
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

223919:F3K33 RS14910
gene id: 223919:F3K33_RS14910
uniprot id: A0A5P2F1K8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

223919:F3K33 RS12570
gene id: 223919:F3K33_RS12570
uniprot id: A0A5P2EX02
names: Subcellular Location Annotation
messages: Membrane

223919:F3K33 RS13630
gene id: 223919:F3K33_RS13630
uniprot id: A0A5P2EYE3
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

223919:F3K33 RS17800
gene id: 223919:F3K33_RS17800
uniprot id: A0A5P2EZH3
names: Similarity
messages: Belongs to the polypeptide deformylase family.

223919:F3K33 RS23305
gene id: 223919:F3K33_RS23305
uniprot id: A0A5P2EZU9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

223919:F3K33 RS06135
gene id: 223919:F3K33_RS06135
uniprot id: A0A5P2EUT5
names: Function
names: Subcellular Location Annotation
messages: ATPase. Has a role at an early stage in the morphogenesis of the spore coat.
messages: Cytoplasm

223919:F3K33 RS04310
gene id: 223919:F3K33_RS04310
uniprot id: A0A5P2EQB8
names: Subcellular Location Annotation
messages: Membrane

223919:F3K33 RS00925
gene id: 223919:F3K33_RS00925
uniprot id: A0A5P2ENQ4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

223919:F3K33 RS01890
gene id: 223919:F3K33_RS01890
uniprot id: A0A5P2ENY4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

223919:F3K33 RS00170
gene id: 223919:F3K33_RS00170
uniprot id: A0A5P2EN64
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

223919:F3K33 RS08360
gene id: 223919:F3K33_RS08360
uniprot id: A0A5P2ES19
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

223919:F3K33 RS08170
gene id: 223919:F3K33_RS08170
uniprot id: A0A5P2EVU7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

223919:F3K33 RS18350
gene id: 223919:F3K33_RS18350
uniprot id: A0A5P2F1E1
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

223919:F3K33 RS17965
gene id: 223919:F3K33_RS17965
uniprot id: A0A5P2F0J3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

223919:F3K33 RS12080
gene id: 223919:F3K33_RS12080
uniprot id: A0A5P2EWP7
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 51 family.
messages: Homohexamer; trimer of dimers.

223919:F3K33 RS24590
gene id: 223919:F3K33_RS24590
uniprot id: A0A5P2F4R7
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

223919:F3K33 RS12525
gene id: 223919:F3K33_RS12525
uniprot id: A0A5P2EXV0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

223919:F3K33 RS00195
gene id: 223919:F3K33_RS00195
uniprot id: A0A5P2EQQ3
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

223919:F3K33 RS00750
gene id: 223919:F3K33_RS00750
uniprot id: A0A5P2EZ84
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

223919:F3K33 RS17385
gene id: 223919:F3K33_RS17385
uniprot id: A0A5P2EWK5
names: Similarity
messages: Belongs to the hemerythrin family.

223919:F3K33 RS01015
gene id: 223919:F3K33_RS01015
uniprot id: A0A5P2ETX1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

223919:F3K33 RS12435
gene id: 223919:F3K33_RS12435
uniprot id: A0A5P2F599
names: Similarity
messages: Belongs to the ribose-phosphate pyrophosphokinase family.

223919:F3K33 RS06885
gene id: 223919:F3K33_RS06885
uniprot id: A0A5P2EV00
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen.
messages: Homooctamer.

223919:F3K33 RS19370
gene id: 223919:F3K33_RS19370
uniprot id: A0A5P2F1W0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

223919:F3K33 RS16340
gene id: 223919:F3K33_RS16340
uniprot id: A0A5P2EW48
names: Function
names: Similarity
messages: Belongs to the UPF0677 family.
messages: Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity.

223919:F3K33 RS00860
gene id: 223919:F3K33_RS00860
uniprot id: A0A5P2ER01
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

223919:F3K33 RS02480
gene id: 223919:F3K33_RS02480
uniprot id: A0A5P2EP67
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

223919:F3K33 RS18740
gene id: 223919:F3K33_RS18740
uniprot id: A0A5P2F8B7
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

223919:F3K33 RS20650
gene id: 223919:F3K33_RS20650
uniprot id: A0A5P2F2I3
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 4 family.
messages: Binds 1 NAD(+) per subunit.
messages: Homotetramer.

223919:F3K33 RS24005
gene id: 223919:F3K33_RS24005
uniprot id: A0A5P2F4F7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

223919:F3K33 RS08800
gene id: 223919:F3K33_RS08800
uniprot id: A0A5P2ESJ3
names: Subcellular Location Annotation
messages: Membrane

223919:F3K33 RS16685
gene id: 223919:F3K33_RS16685
uniprot id: A0A5P2EWA0
names: Subcellular Location Annotation
messages: Membrane

223919:F3K33 RS10655
gene id: 223919:F3K33_RS10655
uniprot id: A0A5P2F4E0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

223919:F3K33 RS16940
gene id: 223919:F3K33_RS16940
uniprot id: A0A5P2F0R9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein SsuA/TauA family.
messages: Periplasm

223919:F3K33 RS20885
gene id: 223919:F3K33_RS20885
uniprot id: A0A5P2F4Q6
names: Subcellular Location Annotation
messages: Cell membrane

223919:F3K33 RS09140
gene id: 223919:F3K33_RS09140
uniprot id: A0A5P2EYB7
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.

223919:F3K33 RS09485
gene id: 223919:F3K33_RS09485
uniprot id: A0A5P2EWB4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

223919:F3K33 RS09365
gene id: 223919:F3K33_RS09365
uniprot id: A0A5P2ESR8
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

223919:F3K33 RS07675
gene id: 223919:F3K33_RS07675
uniprot id: A0A5P2ERX4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the branched chain amino acid transporter family.
messages: Cell membrane
messages: Component of the transport system for branched-chain amino acids.
messages: Membrane

223919:F3K33 RS10400
gene id: 223919:F3K33_RS10400
uniprot id: A0A5P2EVV8
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

223919:F3K33 RS24660
gene id: 223919:F3K33_RS24660
uniprot id: A0A5P2F082
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

223919:F3K33 RS05320
gene id: 223919:F3K33_RS05320
uniprot id: A0A5P2EQR8
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by fructose 1,6-bisphosphate (FBP).
messages: Belongs to the LDH/MDH superfamily. LDH family.
messages: Catalyzes the conversion of lactate to pyruvate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

223919:F3K33 RS25855
gene id: 223919:F3K33_RS25855
uniprot id: A0A5P2FC82
names: Similarity
messages: Belongs to the leucine-binding protein family.

223919:F3K33 RS07005
gene id: 223919:F3K33_RS07005
uniprot id: A0A5P2F2G3
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

223919:F3K33 RS03405
gene id: 223919:F3K33_RS03405
uniprot id: A0A5P2F0K1
names: Similarity
messages: Belongs to the sigma-54 factor family.

223919:F3K33 RS07235
gene id: 223919:F3K33_RS07235
uniprot id: A0A5P2ERQ4
names: Subcellular Location Annotation
messages: Membrane

223919:F3K33 RS25760
gene id: 223919:F3K33_RS25760
uniprot id: A0A5P2F3A0
names: Similarity
messages: Belongs to the DEAD box helicase family.

223919:F3K33 RS02665
gene id: 223919:F3K33_RS02665
uniprot id: A0A5P2ER53
names: Subcellular Location Annotation
messages: Membrane

223919:F3K33 RS05235
gene id: 223919:F3K33_RS05235
uniprot id: A0A5P2EU99
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

223919:F3K33 RS03070
gene id: 223919:F3K33_RS03070
uniprot id: A0A5P2EPM9
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

223919:F3K33 RS15250
gene id: 223919:F3K33_RS15250
uniprot id: A0A5P2F1S6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

223919:F3K33 RS24970
gene id: 223919:F3K33_RS24970
uniprot id: A0A5P2F6W3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation.

223919:F3K33 RS14465
gene id: 223919:F3K33_RS14465
uniprot id: A0A5P2EYT8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

223919:F3K33 RS00470
gene id: 223919:F3K33_RS00470
uniprot id: A0A5P2ENJ1
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

223919:F3K33 RS01375
gene id: 223919:F3K33_RS01375
uniprot id: A0A5P2EZK7
names: Similarity
messages: Belongs to the DtxR/MntR family.

223919:F3K33 RS15295
gene id: 223919:F3K33_RS15295
uniprot id: A0A5P2F6Q4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

223919:F3K33 RS20295
gene id: 223919:F3K33_RS20295
uniprot id: A0A5P2F0Y1
names: Subcellular Location Annotation
messages: Membrane

223919:F3K33 RS20345
gene id: 223919:F3K33_RS20345
uniprot id: A0A5P2F0Z1
names: Similarity
messages: Belongs to the EamA transporter family.

223919:F3K33 RS07790
gene id: 223919:F3K33_RS07790
uniprot id: A0A5P2ERZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CotF family.
messages: Spore coat

223919:F3K33 RS25375
gene id: 223919:F3K33_RS25375
uniprot id: A0A5P2F332
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

223919:F3K33 RS00180
gene id: 223919:F3K33_RS00180
uniprot id: A0A5P2ERJ9
names: Function
names: Similarity
messages: Belongs to the methylglyoxal synthase family.
messages: Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.

223919:F3K33 RS10730
gene id: 223919:F3K33_RS10730
uniprot id: A0A5P2ETH4
names: Function
messages: Component of the dihydroxyacetone kinase complex, which is responsible for the phosphoenolpyruvate (PEP)-dependent phosphorylation of dihydroxyacetone. DhaM serves as the phosphoryl donor. Is phosphorylated by phosphoenolpyruvate in an EI- and HPr-dependent reaction, and a phosphorelay system on histidine residues finally leads to phosphoryl transfer to DhaL and dihydroxyacetone.

223919:F3K33 RS03235
gene id: 223919:F3K33_RS03235
uniprot id: A0A5P2ERE9
names: Function
names: Similarity
messages: Belongs to the LarC family.
messages: Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2+), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor-dependent enzymes.

223919:F3K33 RS05525
gene id: 223919:F3K33_RS05525
uniprot id: A0A5P2EQV4
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

223919:F3K33 RS04755
gene id: 223919:F3K33_RS04755
uniprot id: A0A5P2F1A1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

223919:F3K33 RS01340
gene id: 223919:F3K33_RS01340
uniprot id: A0A5P2ENN2
names: Similarity
messages: Belongs to the mannitol dehydrogenase family.

223919:F3K33 RS25380
gene id: 223919:F3K33_RS25380
uniprot id: A0A5P2F4C2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
messages: Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD).

223919:F3K33 RS21840
gene id: 223919:F3K33_RS21840
uniprot id: A0A5P2EZ39
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: Membrane

223919:F3K33 RS19275
gene id: 223919:F3K33_RS19275
uniprot id: A0A5P2F0F0
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

223919:F3K33 RS09825
gene id: 223919:F3K33_RS09825
uniprot id: A0A5P2ET15
names: PTM
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.
messages: Carbamylation allows a single lysine to coordinate two divalent metal cations.

223919:F3K33 RS15305
gene id: 223919:F3K33_RS15305
uniprot id: A0A5P2EYD2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

223919:F3K33 RS04540
gene id: 223919:F3K33_RS04540
uniprot id: A0A5P2F161
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

223919:F3K33 RS05970
gene id: 223919:F3K33_RS05970
uniprot id: A0A5P2ET73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

223919:F3K33 RS12850
gene id: 223919:F3K33_RS12850
uniprot id: A0A5P2EYD5
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

223919:F3K33 RS22760
gene id: 223919:F3K33_RS22760
uniprot id: A0A5P2FAM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

223919:F3K33 RS25640
gene id: 223919:F3K33_RS25640
uniprot id: A0A5P2F0Y7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 32 family.
messages: Cytoplasm
messages: Enables the bacterium to metabolize sucrose as a sole carbon source.

223919:F3K33 RS17720
gene id: 223919:F3K33_RS17720
uniprot id: A0A5P2EZJ5
names: Similarity
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.

223919:F3K33 RS03920
gene id: 223919:F3K33_RS03920
uniprot id: A0A5P2EPY1
names: Subcellular Location Annotation
messages: Membrane

223919:F3K33 RS13810
gene id: 223919:F3K33_RS13810
uniprot id: A0A5P2EXL7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Cell membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

223919:F3K33 RS16155
gene id: 223919:F3K33_RS16155
uniprot id: A0A5P2EYU3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

223919:F3K33 RS06155
gene id: 223919:F3K33_RS06155
uniprot id: A0A5P2EQY3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

223919:F3K33 RS11400
gene id: 223919:F3K33_RS11400
uniprot id: A0A5P2EWE4
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

223919:F3K33 RS23165
gene id: 223919:F3K33_RS23165
uniprot id: A0A5P2F222
names: Subcellular Location Annotation
messages: Membrane

223919:F3K33 RS18795
gene id: 223919:F3K33_RS18795
uniprot id: A0A5P2F8C9
names: Similarity
messages: Belongs to the FGGY kinase family.

223919:F3K33 RS01900
gene id: 223919:F3K33_RS01900
uniprot id: A0A5P2ESD9
names: Similarity
messages: Belongs to the UPF0178 family.

223919:F3K33 RS07990
gene id: 223919:F3K33_RS07990
uniprot id: A0A5P2ERU9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

223919:F3K33 RS01345
gene id: 223919:F3K33_RS01345
uniprot id: A0A5P2ENX7
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

223919:F3K33 RS20610
gene id: 223919:F3K33_RS20610
uniprot id: A0A5P2EY39
names: Subcellular Location Annotation
messages: Membrane

223919:F3K33 RS25315
gene id: 223919:F3K33_RS25315
uniprot id: A0A5P2F0S3
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

223919:F3K33 RS01460
gene id: 223919:F3K33_RS01460
uniprot id: A0A5P2EQK6
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

223919:F3K33 RS24390
gene id: 223919:F3K33_RS24390
uniprot id: A0A5P2F6K9
names: Subcellular Location Annotation
messages: Membrane

223919:F3K33 RS26220
gene id: 223919:F3K33_RS26220
uniprot id: A0A5P2F4S0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

223919:F3K33 RS05130
gene id: 223919:F3K33_RS05130
uniprot id: A0A5P2EU12
names: Similarity
messages: Belongs to the PHP hydrolase family. HisK subfamily.

223919:F3K33 RS19785
gene id: 223919:F3K33_RS19785
uniprot id: A0A5P2F455
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 32 family.
messages: Cytoplasm
messages: Enables the bacterium to metabolize sucrose as a sole carbon source.

223919:F3K33 RS21520
gene id: 223919:F3K33_RS21520
uniprot id: A0A5P2EYW7
names: Similarity
messages: Belongs to the glutamine synthetase family.

223919:F3K33 RS06495
gene id: 223919:F3K33_RS06495
uniprot id: A0A5P2F274
names: Similarity
messages: Belongs to the peptidase M16 family.

223919:F3K33 RS13670
gene id: 223919:F3K33_RS13670
uniprot id: A0A5P2EUX0
names: Cofactor
messages: Binds 1 Mg(2+) ion per trimer.

223919:F3K33 RS03210
gene id: 223919:F3K33_RS03210
uniprot id: A0A5P2EV07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

223919:F3K33 RS14630
gene id: 223919:F3K33_RS14630
uniprot id: A0A5P2EZB3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lactate permease family.
messages: Cell membrane
messages: Membrane
messages: Uptake of L-lactate across the membrane. Can also transport D-lactate and glycolate.

223919:F3K33 RS17455
gene id: 223919:F3K33_RS17455
uniprot id: A0A5P2F0Z9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

223919:F3K33 RS09980
gene id: 223919:F3K33_RS09980
uniprot id: A0A5P2ET38
names: Similarity
messages: Belongs to the NifD/NifK/NifE/NifN family.

223919:F3K33 RS04315
gene id: 223919:F3K33_RS04315
uniprot id: A0A5P2EQ58
names: Subcellular Location Annotation
messages: Membrane

223919:F3K33 RS07040
gene id: 223919:F3K33_RS07040
uniprot id: A0A5P2ETT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

223919:F3K33 RS00885
gene id: 223919:F3K33_RS00885
uniprot id: A0A5P2ENF3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

223919:F3K33 RS25095
gene id: 223919:F3K33_RS25095
uniprot id: A0A5P2F0P1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

223919:F3K33 RS23015
gene id: 223919:F3K33_RS23015
uniprot id: A0A5P2F3X3
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

223919:F3K33 RS07400
gene id: 223919:F3K33_RS07400
uniprot id: A0A5P2ERW0
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

223919:F3K33 RS00985
gene id: 223919:F3K33_RS00985
uniprot id: A0A5P2ENH1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

223919:F3K33 RS25860
gene id: 223919:F3K33_RS25860
uniprot id: A0A5P2F418
names: Subcellular Location Annotation
messages: Membrane

223919:F3K33 RS07245
gene id: 223919:F3K33_RS07245
uniprot id: A0A5P2ERQ3
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.

223919:F3K33 RS03860
gene id: 223919:F3K33_RS03860
uniprot id: A0A5P2EQ11
names: Subcellular Location Annotation
messages: Membrane

223919:F3K33 RS23490
gene id: 223919:F3K33_RS23490
uniprot id: A0A5P2F464
names: Similarity
messages: Belongs to the Tlp family.

223919:F3K33 RS14650
gene id: 223919:F3K33_RS14650
uniprot id: A0A5P2F1G1
names: Subcellular Location Annotation
messages: Membrane

223919:F3K33 RS11535
gene id: 223919:F3K33_RS11535
uniprot id: A0A5P2F4V2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UbiX/PAD1 family. YclB subfamily.
messages: Homododecamer.
messages: Involved in the non-oxidative decarboxylation and detoxification of phenolic derivatives. Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for phenolic acid decarboxylase.

223919:F3K33 RS04530
gene id: 223919:F3K33_RS04530
uniprot id: A0A5P2ETP5
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

223919:F3K33 RS13620
gene id: 223919:F3K33_RS13620
uniprot id: A0A5P2EUV8
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

223919:F3K33 RS10915
gene id: 223919:F3K33_RS10915
uniprot id: A0A5P2EW71
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

223919:F3K33 RS10865
gene id: 223919:F3K33_RS10865
uniprot id: A0A5P2EW61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0060 family.
messages: Cell membrane

223919:F3K33 RS18515
gene id: 223919:F3K33_RS18515
uniprot id: A0A5P2F1G5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily.
messages: Cell membrane

223919:F3K33 RS20990
gene id: 223919:F3K33_RS20990
uniprot id: A0A5P2EYA6
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

223919:F3K33 RS07550
gene id: 223919:F3K33_RS07550
uniprot id: A0A5P2ERY8
names: Cofactor
names: Similarity
messages: Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.
messages: Binds 3 [4Fe-4S] clusters per subunit.

223919:F3K33 RS21100
gene id: 223919:F3K33_RS21100
uniprot id: A0A5P2EYC6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

223919:F3K33 RS18825
gene id: 223919:F3K33_RS18825
uniprot id: A0A5P2EXI0
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

223919:F3K33 RS09915
gene id: 223919:F3K33_RS09915
uniprot id: A0A5P2EYP9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer and homodimer.

223919:F3K33 RS14635
gene id: 223919:F3K33_RS14635
uniprot id: A0A5P2F6E6
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

223919:F3K33 RS05240
gene id: 223919:F3K33_RS05240
uniprot id: A0A5P2F1I7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

223919:F3K33 RS03110
gene id: 223919:F3K33_RS03110
uniprot id: A0A5P2EUY6
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

223919:F3K33 RS01025
gene id: 223919:F3K33_RS01025
uniprot id: A0A5P2ENS1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.
messages: Cytoplasm
messages: Monomer.

223919:F3K33 RS07905
gene id: 223919:F3K33_RS07905
uniprot id: A0A5P2EU97
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

223919:F3K33 RS00955
gene id: 223919:F3K33_RS00955
uniprot id: A0A5P2EZC9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

223919:F3K33 RS05955
gene id: 223919:F3K33_RS05955
uniprot id: A0A5P2ER38
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

223919:F3K33 RS14795
gene id: 223919:F3K33_RS14795
uniprot id: A0A5P2EVM2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

223919:F3K33 RS21530
gene id: 223919:F3K33_RS21530
uniprot id: A0A5P2F1A0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

223919:F3K33 RS10510
gene id: 223919:F3K33_RS10510
uniprot id: A0A5P2ET59
names: Similarity
messages: Belongs to the PHP hydrolase family. HisK subfamily.

223919:F3K33 RS01145
gene id: 223919:F3K33_RS01145
uniprot id: A0A5P2EQE5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

223919:F3K33 RS05630
gene id: 223919:F3K33_RS05630
uniprot id: A0A5P2EQW8
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

223919:F3K33 RS04980
gene id: 223919:F3K33_RS04980
uniprot id: A0A5P2EU44
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MurCDEF family. MurT subfamily.
messages: Forms a heterodimer with GatD.
messages: The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The MurT subunit catalyzes the ATP-dependent amidation of D-glutamate residue of lipid II, converting it to an isoglutamine residue.

223919:F3K33 RS23730
gene id: 223919:F3K33_RS23730
uniprot id: A0A5P2EZY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

223919:F3K33 RS20430
gene id: 223919:F3K33_RS20430
uniprot id: A0A5P2F1Q2
names: Similarity
messages: Belongs to the peptidase S33 family.

223919:F3K33 RS25370
gene id: 223919:F3K33_RS25370
uniprot id: A0A5P2F0T3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

223919:F3K33 RS03520
gene id: 223919:F3K33_RS03520
uniprot id: A0A5P2EV61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

223919:F3K33 RS24600
gene id: 223919:F3K33_RS24600
uniprot id: A0A5P2F3C0
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

223919:F3K33 RS23965
gene id: 223919:F3K33_RS23965
uniprot id: A0A5P2F6D4
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

223919:F3K33 RS05625
gene id: 223919:F3K33_RS05625
uniprot id: A0A5P2EQP7
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

223919:F3K33 RS16465
gene id: 223919:F3K33_RS16465
uniprot id: A0A5P2EZV9
names: Subcellular Location Annotation
messages: Membrane

223919:F3K33 RS14685
gene id: 223919:F3K33_RS14685
uniprot id: A0A5P2EYX3
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

223919:F3K33 RS15540
gene id: 223919:F3K33_RS15540
uniprot id: A0A5P2EVU3
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

223919:F3K33 RS21825
gene id: 223919:F3K33_RS21825
uniprot id: A0A5P2F5A3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliJ family.
messages: Cell membrane
messages: Membrane

223919:F3K33 RS24645
gene id: 223919:F3K33_RS24645
uniprot id: A0A5P2FBM3
names: Similarity
messages: Belongs to the MotB family.

223919:F3K33 RS11610
gene id: 223919:F3K33_RS11610
uniprot id: A0A5P2EXS9
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. Nitrilase family.

223919:F3K33 RS07570
gene id: 223919:F3K33_RS07570
uniprot id: A0A5P2EVB4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpC family.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

223919:F3K33 RS22110
gene id: 223919:F3K33_RS22110
uniprot id: A0A5P2F2P5
names: Similarity
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.

223919:F3K33 RS12665
gene id: 223919:F3K33_RS12665
uniprot id: A0A5P2EUD2
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

223919:F3K33 RS23950
gene id: 223919:F3K33_RS23950
uniprot id: A0A5P2F4E5
names: Subcellular Location Annotation
messages: Membrane

223919:F3K33 RS13765
gene id: 223919:F3K33_RS13765
uniprot id: A0A5P2F0W1
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

223919:F3K33 RS15255
gene id: 223919:F3K33_RS15255
uniprot id: A0A5P2EVG8
names: Function
names: Similarity
messages: Belongs to the complex I 30 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

223919:F3K33 RS15725
gene id: 223919:F3K33_RS15725
uniprot id: A0A5P2EYL7
names: Domain
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
messages: Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.

223919:F3K33 RS04230
gene id: 223919:F3K33_RS04230
uniprot id: A0A5P2ETN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

223919:F3K33 RS01640
gene id: 223919:F3K33_RS01640
uniprot id: A0A5P2EZQ7
names: Similarity
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

223919:F3K33 RS09875
gene id: 223919:F3K33_RS09875
uniprot id: A0A5P2ET18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

223919:F3K33 RS10420
gene id: 223919:F3K33_RS10420
uniprot id: A0A5P2ETB8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TenA family.
messages: Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway.
messages: Homotetramer.

223919:F3K33 RS18595
gene id: 223919:F3K33_RS18595
uniprot id: A0A5P2ET81
names: Function
names: Similarity
messages: Belongs to the transposase 11 family.
messages: Involved in the transposition of the insertion sequence IS5.

223919:F3K33 RS14270
gene id: 223919:F3K33_RS14270
uniprot id: A0A5P2EV58
names: Similarity
messages: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family.

223919:F3K33 RS09710
gene id: 223919:F3K33_RS09710
uniprot id: A0A5P2ESX8
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

223919:F3K33 RS08775
gene id: 223919:F3K33_RS08775
uniprot id: A0A5P2F3C3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

223919:F3K33 RS18000
gene id: 223919:F3K33_RS18000
uniprot id: A0A5P2EX23
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

223919:F3K33 RS11215
gene id: 223919:F3K33_RS11215
uniprot id: A0A5P2ETQ8
names: Similarity
messages: Belongs to the hemerythrin family.

223919:F3K33 RS06160
gene id: 223919:F3K33_RS06160
uniprot id: A0A5P2ER55
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

223919:F3K33 RS09835
gene id: 223919:F3K33_RS09835
uniprot id: A0A5P2EVJ4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia.

223919:F3K33 RS12785
gene id: 223919:F3K33_RS12785
uniprot id: A0A5P2EX41
names: Function
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. NagD family.
messages: Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro.

223919:F3K33 RS25510
gene id: 223919:F3K33_RS25510
uniprot id: A0A5P2F762
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

223919:F3K33 RS26205
gene id: 223919:F3K33_RS26205
uniprot id: A0A5P2F1B7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OXA1/ALB3/YidC family.
messages: Membrane

223919:F3K33 RS21860
gene id: 223919:F3K33_RS21860
uniprot id: A0A5P2F3B2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod.

223919:F3K33 RS14395
gene id: 223919:F3K33_RS14395
uniprot id: A0A5P2EXY3
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. SigI subfamily.
messages: Cytoplasm
messages: Interacts with RsgI.
messages: Negatively regulated by the anti-sigma-I factor RsgI.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

223919:F3K33 RS22830
gene id: 223919:F3K33_RS22830
uniprot id: A0A5P2EZV3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the arabinose isomerase family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the conversion of L-arabinose to L-ribulose.

223919:F3K33 RS13285
gene id: 223919:F3K33_RS13285
uniprot id: A0A5P2EUJ4
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

223919:F3K33 RS04670
gene id: 223919:F3K33_RS04670
uniprot id: A0A5P2EQ86
names: Similarity
messages: Belongs to the peptidase S8 family.

223919:F3K33 RS04030
gene id: 223919:F3K33_RS04030
uniprot id: A0A5P2ERW8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

223919:F3K33 RS08540
gene id: 223919:F3K33_RS08540
uniprot id: A0A5P2EVT8
names: Similarity
messages: Belongs to the UDPGP type 2 family.

223919:F3K33 RS03655
gene id: 223919:F3K33_RS03655
uniprot id: A0A5P2ERN5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

223919:F3K33 RS20975
gene id: 223919:F3K33_RS20975
uniprot id: A0A5P2F9P6
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

223919:F3K33 RS24130
gene id: 223919:F3K33_RS24130
uniprot id: A0A5P2EZZ7
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

223919:F3K33 RS14845
gene id: 223919:F3K33_RS14845
uniprot id: A0A5P2EVA5
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

223919:F3K33 RS08265
gene id: 223919:F3K33_RS08265
uniprot id: A0A5P2EUH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

223919:F3K33 RS07045
gene id: 223919:F3K33_RS07045
uniprot id: A0A5P2EV26
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

223919:F3K33 RS04960
gene id: 223919:F3K33_RS04960
uniprot id: A0A5P2EQL1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial solute-binding protein 2 family.
messages: Periplasm
messages: The ABC transporter complex is composed of one ATP-binding protein (MglA), two transmembrane proteins (MglC) and a solute-binding protein (MglB).

223919:F3K33 RS03580
gene id: 223919:F3K33_RS03580
uniprot id: A0A5P2EPW4
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

223919:F3K33 RS03120
gene id: 223919:F3K33_RS03120
uniprot id: A0A5P2EPN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily.
messages: Cell membrane

223919:F3K33 RS06925
gene id: 223919:F3K33_RS06925
uniprot id: A0A5P2F122
names: Similarity
messages: Belongs to the UPF0735 family.

223919:F3K33 RS01630
gene id: 223919:F3K33_RS01630
uniprot id: A0A5P2EWL8
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

223919:F3K33 RS19750
gene id: 223919:F3K33_RS19750
uniprot id: A0A5P2EXS5
names: Similarity
messages: Belongs to the glycosyl hydrolase 32 family.

223919:F3K33 RS15170
gene id: 223919:F3K33_RS15170
uniprot id: A0A5P2EYA7
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

223919:F3K33 RS00335
gene id: 223919:F3K33_RS00335
uniprot id: A0A5P2EPZ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ribonuclease M5 family.
messages: Cytoplasm
messages: Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step.

223919:F3K33 RS21775
gene id: 223919:F3K33_RS21775
uniprot id: A0A5P2F587
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliR/MopE/SpaR family.
messages: Belongs to the type III secretion exporter family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

223919:F3K33 RS08140
gene id: 223919:F3K33_RS08140
uniprot id: A0A5P2ERY2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-3 family.
messages: Cytoplasm
messages: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
messages: Monomer.

223919:F3K33 RS04545
gene id: 223919:F3K33_RS04545
uniprot id: A0A5P2F5N4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

223919:F3K33 RS25755
gene id: 223919:F3K33_RS25755
uniprot id: A0A5P2F110
names: Domain
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

223919:F3K33 RS15380
gene id: 223919:F3K33_RS15380
uniprot id: A0A5P2EVM4
names: Function
names: Similarity
messages: Belongs to the flavodoxin family.
messages: Low-potential electron donor to a number of redox enzymes.

223919:F3K33 RS12755
gene id: 223919:F3K33_RS12755
uniprot id: A0A5P2F0A4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CutC family.
messages: Cytoplasm
messages: Once thought to be involved in copper homeostasis, experiments in E.coli have shown this is not the case.

223919:F3K33 RS16160
gene id: 223919:F3K33_RS16160
uniprot id: A0A5P2F2B9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

223919:F3K33 RS15445
gene id: 223919:F3K33_RS15445
uniprot id: A0A5P2EYF6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

223919:F3K33 RS05680
gene id: 223919:F3K33_RS05680
uniprot id: A0A5P2EQX9
names: Subcellular Location Annotation
messages: Membrane

223919:F3K33 RS02935
gene id: 223919:F3K33_RS02935
uniprot id: A0A5P2ERA1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

223919:F3K33 RS18790
gene id: 223919:F3K33_RS18790
uniprot id: A0A5P2F1L3
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

223919:F3K33 RS11190
gene id: 223919:F3K33_RS11190
uniprot id: A0A5P2F4P1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily.
messages: Cell membrane

223919:F3K33 RS16335
gene id: 223919:F3K33_RS16335
uniprot id: A0A5P2EW96
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

223919:F3K33 RS23880
gene id: 223919:F3K33_RS23880
uniprot id: A0A5P2F012
names: Subcellular Location Annotation
messages: Membrane

223919:F3K33 RS10750
gene id: 223919:F3K33_RS10750
uniprot id: A0A5P2EXC7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

223919:F3K33 RS18585
gene id: 223919:F3K33_RS18585
uniprot id: A0A5P2F3I7
names: Subcellular Location Annotation
messages: Membrane

223919:F3K33 RS22785
gene id: 223919:F3K33_RS22785
uniprot id: A0A5P2EZJ9
names: Subcellular Location Annotation
messages: Membrane

223919:F3K33 RS19845
gene id: 223919:F3K33_RS19845
uniprot id: A0A5P2F465
names: Function
messages: Component of the dihydroxyacetone kinase complex, which is responsible for the phosphoenolpyruvate (PEP)-dependent phosphorylation of dihydroxyacetone. DhaM serves as the phosphoryl donor. Is phosphorylated by phosphoenolpyruvate in an EI- and HPr-dependent reaction, and a phosphorelay system on histidine residues finally leads to phosphoryl transfer to DhaL and dihydroxyacetone.

223919:F3K33 RS20950
gene id: 223919:F3K33_RS20950
uniprot id: A0A5P2EYL5
names: Similarity
messages: Belongs to the IlvD/Edd family.

223919:F3K33 RS11965
gene id: 223919:F3K33_RS11965
uniprot id: A0A5P2EXJ4
names: Similarity
messages: Belongs to the hemerythrin family.

223919:F3K33 RS22930
gene id: 223919:F3K33_RS22930
uniprot id: A0A5P2EZX5
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

223919:F3K33 RS04525
gene id: 223919:F3K33_RS04525
uniprot id: A0A5P2ESE3
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

223919:F3K33 RS26215
gene id: 223919:F3K33_RS26215
uniprot id: A0A5P2F3H0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

223919:F3K33 RS24420
gene id: 223919:F3K33_RS24420
uniprot id: A0A5P2F3V7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

223919:F3K33 RS02840
gene id: 223919:F3K33_RS02840
uniprot id: A0A5P2ESX7
names: Similarity
messages: Belongs to the RutC family.

223919:F3K33 RS00890
gene id: 223919:F3K33_RS00890
uniprot id: A0A5P2EQ87
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

223919:F3K33 RS04590
gene id: 223919:F3K33_RS04590
uniprot id: A0A5P2ETW5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

223919:F3K33 RS26100
gene id: 223919:F3K33_RS26100
uniprot id: A0A5P2F166
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GdpP/PdeA phosphodiesterase family.
messages: Cell membrane
messages: For phosphodiesterase activity, probably binds 2 Mn(2+) per subunit.
messages: Has phosphodiesterase (PDE) activity against cyclic-di-AMP (c-di-AMP).

223919:F3K33 RS09760
gene id: 223919:F3K33_RS09760
uniprot id: A0A5P2EYM4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

223919:F3K33 RS15120
gene id: 223919:F3K33_RS15120
uniprot id: A0A5P2EZ41
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MenA family. Type 1 subfamily.
messages: Cell membrane
messages: Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK).
messages: Membrane

223919:F3K33 RS00600
gene id: 223919:F3K33_RS00600
uniprot id: A0A5P2EZ67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

223919:F3K33 RS04940
gene id: 223919:F3K33_RS04940
uniprot id: A0A5P2F1T2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

223919:F3K33 RS24915
gene id: 223919:F3K33_RS24915
uniprot id: A0A5P2F3I6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gluconeogenesis factor family.
messages: Cytoplasm
messages: Required for morphogenesis under gluconeogenic growth conditions.

223919:F3K33 RS06840
gene id: 223919:F3K33_RS06840
uniprot id: A0A5P2EV63
names: Similarity
messages: Belongs to the cycloisomerase 2 family.

223919:F3K33 RS08460
gene id: 223919:F3K33_RS08460
uniprot id: A0A5P2ES34
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

223919:F3K33 RS00320
gene id: 223919:F3K33_RS00320
uniprot id: A0A5P2ENG5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

223919:F3K33 RS08210
gene id: 223919:F3K33_RS08210
uniprot id: A0A5P2ES58
names: Subcellular Location Annotation
messages: Membrane

223919:F3K33 RS21865
gene id: 223919:F3K33_RS21865
uniprot id: A0A5P2FA80
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

223919:F3K33 RS22700
gene id: 223919:F3K33_RS22700
uniprot id: A0A5P2F3R9
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

223919:F3K33 RS14950
gene id: 223919:F3K33_RS14950
uniprot id: A0A5P2EZ10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

223919:F3K33 RS12935
gene id: 223919:F3K33_RS12935
uniprot id: A0A5P2EUK3
names: Similarity
messages: Belongs to the peptidase C40 family.

223919:F3K33 RS00460
gene id: 223919:F3K33_RS00460
uniprot id: A0A5P2ETM8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

223919:F3K33 RS19460
gene id: 223919:F3K33_RS19460
uniprot id: A0A5P2F094
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane.

223919:F3K33 RS12300
gene id: 223919:F3K33_RS12300
uniprot id: A0A5P2EU18
names: Similarity
messages: Belongs to the FldB/FldC dehydratase alpha/beta subunit family.

223919:F3K33 RS24145
gene id: 223919:F3K33_RS24145
uniprot id: A0A5P2F059
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

223919:F3K33 RS00725
gene id: 223919:F3K33_RS00725
uniprot id: A0A5P2ENS8
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

223919:F3K33 RS21940
gene id: 223919:F3K33_RS21940
uniprot id: A0A5P2EZ58
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

223919:F3K33 RS08235
gene id: 223919:F3K33_RS08235
uniprot id: A0A5P2EUR7
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

223919:F3K33 RS19225
gene id: 223919:F3K33_RS19225
uniprot id: A0A5P2F0D9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

223919:F3K33 RS08880
gene id: 223919:F3K33_RS08880
uniprot id: A0A5P2F3E6
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

223919:F3K33 RS02505
gene id: 223919:F3K33_RS02505
uniprot id: A0A5P2ESN0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

223919:F3K33 RS03515
gene id: 223919:F3K33_RS03515
uniprot id: A0A5P2ES97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

223919:F3K33 RS06880
gene id: 223919:F3K33_RS06880
uniprot id: A0A5P2ETQ2
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

223919:F3K33 RS06915
gene id: 223919:F3K33_RS06915
uniprot id: A0A5P2ERJ7
names: Similarity
messages: Belongs to the threonine synthase family.

223919:F3K33 RS24620
gene id: 223919:F3K33_RS24620
uniprot id: A0A5P2F0J1
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

223919:F3K33 RS07585
gene id: 223919:F3K33_RS07585
uniprot id: A0A5P2EUF1
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

223919:F3K33 RS17655
gene id: 223919:F3K33_RS17655
uniprot id: A0A5P2F127
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

223919:F3K33 RS05015
gene id: 223919:F3K33_RS05015
uniprot id: A0A5P2EQK4
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane.

223919:F3K33 RS12680
gene id: 223919:F3K33_RS12680
uniprot id: A0A5P2EYB0
names: Similarity
messages: Belongs to the glycosyl hydrolase 25 family.

223919:F3K33 RS06875
gene id: 223919:F3K33_RS06875
uniprot id: A0A5P2ERJ1
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

223919:F3K33 RS11735
gene id: 223919:F3K33_RS11735
uniprot id: A0A5P2EXG1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

223919:F3K33 RS13905
gene id: 223919:F3K33_RS13905
uniprot id: A0A5P2EYX2
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

223919:F3K33 RS09715
gene id: 223919:F3K33_RS09715
uniprot id: A0A5P2EVH6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

223919:F3K33 RS20170
gene id: 223919:F3K33_RS20170
uniprot id: A0A5P2F292
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

223919:F3K33 RS06795
gene id: 223919:F3K33_RS06795
uniprot id: A0A5P2F2C1
names: Function
messages: Decarboxylates L-threonine-O-3-phosphate to yield (R)-1-amino-2-propanol O-2-phosphate, the precursor for the linkage between the nucleotide loop and the corrin ring in cobalamin.

223919:F3K33 RS14660
gene id: 223919:F3K33_RS14660
uniprot id: A0A5P2EV78
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

223919:F3K33 RS08450
gene id: 223919:F3K33_RS08450
uniprot id: A0A5P2EUV7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

223919:F3K33 RS02875
gene id: 223919:F3K33_RS02875
uniprot id: A0A5P2EPP5
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

223919:F3K33 RS17995
gene id: 223919:F3K33_RS17995
uniprot id: A0A5P2EXA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

223919:F3K33 RS07060
gene id: 223919:F3K33_RS07060
uniprot id: A0A5P2EU52
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRA-CH family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
messages: Cytoplasm
messages: Homodimer.

223919:F3K33 RS00165
gene id: 223919:F3K33_RS00165
uniprot id: A0A5P2ENK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0073 (Hly-III) family.
messages: Membrane

223919:F3K33 RS06565
gene id: 223919:F3K33_RS06565
uniprot id: A0A5P2ERC5
names: Subcellular Location Annotation
messages: Membrane

223919:F3K33 RS19210
gene id: 223919:F3K33_RS19210
uniprot id: A0A5P2F1T5
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

223919:F3K33 RS03615
gene id: 223919:F3K33_RS03615
uniprot id: A0A5P2F0P4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

223919:F3K33 RS15655
gene id: 223919:F3K33_RS15655
uniprot id: A0A5P2EZE8
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

223919:F3K33 RS11175
gene id: 223919:F3K33_RS11175
uniprot id: A0A5P2EWA6
names: Similarity
messages: Belongs to the thioredoxin family.

223919:F3K33 RS24930
gene id: 223919:F3K33_RS24930
uniprot id: A0A5P2F118
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

223919:F3K33 RS21645
gene id: 223919:F3K33_RS21645
uniprot id: A0A5P2F1B9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

223919:F3K33 RS04305
gene id: 223919:F3K33_RS04305
uniprot id: A0A5P2EQ85
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HCP family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Binds 1 hybrid [4Fe-2O-2S] cluster.
messages: Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
messages: Cytoplasm

223919:F3K33 RS18510
gene id: 223919:F3K33_RS18510
uniprot id: A0A5P2F0T0
names: Subcellular Location Annotation
messages: Membrane

223919:F3K33 RS05285
gene id: 223919:F3K33_RS05285
uniprot id: A0A5P2EUA9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

223919:F3K33 RS23820
gene id: 223919:F3K33_RS23820
uniprot id: A0A5P2F0E7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

223919:F3K33 RS05975
gene id: 223919:F3K33_RS05975
uniprot id: A0A5P2EUH3
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

223919:F3K33 RS11615
gene id: 223919:F3K33_RS11615
uniprot id: A0A5P2F4W2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

223919:F3K33 RS01240
gene id: 223919:F3K33_RS01240
uniprot id: A0A5P2ENL5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 2 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

223919:F3K33 RS16985
gene id: 223919:F3K33_RS16985
uniprot id: A0A5P2EZ44
names: Subcellular Location Annotation
messages: Cytoplasm

223919:F3K33 RS06095
gene id: 223919:F3K33_RS06095
uniprot id: A0A5P2ETL9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

223919:F3K33 RS24565
gene id: 223919:F3K33_RS24565
uniprot id: A0A5P2F0H9
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

223919:F3K33 RS04255
gene id: 223919:F3K33_RS04255
uniprot id: A0A5P2EQ78
names: Similarity
messages: Belongs to the thioredoxin family.

223919:F3K33 RS25625
gene id: 223919:F3K33_RS25625
uniprot id: A0A5P2F0P5
names: Subcellular Location Annotation
messages: Membrane

223919:F3K33 RS04385
gene id: 223919:F3K33_RS04385
uniprot id: A0A5P2F130
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

223919:F3K33 RS18635
gene id: 223919:F3K33_RS18635
uniprot id: A0A5P2F3J8
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

223919:F3K33 RS13815
gene id: 223919:F3K33_RS13815
uniprot id: A0A5P2F0X5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

223919:F3K33 RS23745
gene id: 223919:F3K33_RS23745
uniprot id: A0A5P2F4A8
names: Similarity
messages: Belongs to the glycosyl hydrolase 25 family.

223919:F3K33 RS00715
gene id: 223919:F3K33_RS00715
uniprot id: A0A5P2END0
names: Similarity
messages: Belongs to the peptidase M20A family.

223919:F3K33 RS18505
gene id: 223919:F3K33_RS18505
uniprot id: A0A5P2ET81
names: Function
names: Similarity
messages: Belongs to the transposase 11 family.
messages: Involved in the transposition of the insertion sequence IS5.

223919:F3K33 RS21955
gene id: 223919:F3K33_RS21955
uniprot id: A0A5P2F2L5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliS family.
messages: cytosol

223919:F3K33 RS02305
gene id: 223919:F3K33_RS02305
uniprot id: A0A5P2EPG5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

223919:F3K33 RS23610
gene id: 223919:F3K33_RS23610
uniprot id: A0A5P2F665
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane.

223919:F3K33 RS00510
gene id: 223919:F3K33_RS00510
uniprot id: A0A5P2ETN9
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

223919:F3K33 RS11570
gene id: 223919:F3K33_RS11570
uniprot id: A0A5P2ETW3
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

223919:F3K33 RS01080
gene id: 223919:F3K33_RS01080
uniprot id: A0A5P2ENT0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex.
messages: Belongs to the ABC transporter superfamily. Energy-coupling factor EcfA family.
messages: Cell membrane
messages: Forms a stable energy-coupling factor (ECF) transporter complex composed of 2 membrane-embedded substrate-binding proteins (S component), 2 ATP-binding proteins (A component) and 2 transmembrane proteins (T component).
messages: Membrane

223919:F3K33 RS18175
gene id: 223919:F3K33_RS18175
uniprot id: A0A5P2F0M6
names: Subcellular Location Annotation
messages: Membrane

223919:F3K33 RS19870
gene id: 223919:F3K33_RS19870
uniprot id: A0A5P2EXU3
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

223919:F3K33 RS15800
gene id: 223919:F3K33_RS15800
uniprot id: A0A5P2EVU9
names: Subcellular Location Annotation
messages: Membrane

223919:F3K33 RS18670
gene id: 223919:F3K33_RS18670
uniprot id: A0A5P2EZW6
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

223919:F3K33 RS26725
gene id: 223919:F3K33_RS26725
uniprot id: A0A5P2EW89
names: Subcellular Location Annotation
messages: Cell membrane

223919:F3K33 RS00835
gene id: 223919:F3K33_RS00835
uniprot id: A0A5P2EQ74
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. Sigma-S contributes to the protection against external stress, thus playing a role in cellular fitness and survival.

223919:F3K33 RS06460
gene id: 223919:F3K33_RS06460
uniprot id: A0A5P2ER34
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

223919:F3K33 RS21595
gene id: 223919:F3K33_RS21595
uniprot id: A0A5P2F359
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A24 family.
messages: Membrane

223919:F3K33 RS22955
gene id: 223919:F3K33_RS22955
uniprot id: A0A5P2F3W3
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

223919:F3K33 RS07145
gene id: 223919:F3K33_RS07145
uniprot id: A0A5P2ETV3
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

223919:F3K33 RS22260
gene id: 223919:F3K33_RS22260
uniprot id: A0A5P2F2R9
names: Subcellular Location Annotation
messages: Membrane

223919:F3K33 RS07030
gene id: 223919:F3K33_RS07030
uniprot id: A0A5P2ERP5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

223919:F3K33 RS07390
gene id: 223919:F3K33_RS07390
uniprot id: A0A5P2ERJ6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

223919:F3K33 RS00760
gene id: 223919:F3K33_RS00760
uniprot id: A0A5P2ETR9
names: Similarity
messages: Belongs to the CtsR family.

223919:F3K33 RS01290
gene id: 223919:F3K33_RS01290
uniprot id: A0A5P2ENM6
names: Similarity
messages: Belongs to the CapA family.

223919:F3K33 RS10385
gene id: 223919:F3K33_RS10385
uniprot id: A0A5P2EWS4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

223919:F3K33 RS22815
gene id: 223919:F3K33_RS22815
uniprot id: A0A5P2F491
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 3B subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

223919:F3K33 RS23405
gene id: 223919:F3K33_RS23405
uniprot id: A0A5P2F065
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

223919:F3K33 RS19985
gene id: 223919:F3K33_RS19985
uniprot id: A0A5P2F0H3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

223919:F3K33 RS18875
gene id: 223919:F3K33_RS18875
uniprot id: A0A5P2EXI9
names: Subcellular Location Annotation
messages: Membrane

223919:F3K33 RS20855
gene id: 223919:F3K33_RS20855
uniprot id: A0A5P2F0X9
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

223919:F3K33 RS00440
gene id: 223919:F3K33_RS00440
uniprot id: A0A5P2ERP2
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

223919:F3K33 RS03420
gene id: 223919:F3K33_RS03420
uniprot id: A0A5P2EPN5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

223919:F3K33 RS01625
gene id: 223919:F3K33_RS01625
uniprot id: A0A5P2EQN1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

223919:F3K33 RS19820
gene id: 223919:F3K33_RS19820
uniprot id: A0A5P2F0E5
names: Similarity
messages: Belongs to the organic radical-activating enzymes family.

223919:F3K33 RS08740
gene id: 223919:F3K33_RS08740
uniprot id: A0A5P2ES78
names: Subcellular Location Annotation
messages: Membrane

223919:F3K33 RS11675
gene id: 223919:F3K33_RS11675
uniprot id: A0A5P2F4W8
names: Similarity
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

223919:F3K33 RS06955
gene id: 223919:F3K33_RS06955
uniprot id: A0A5P2EU31
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

223919:F3K33 RS01215
gene id: 223919:F3K33_RS01215
uniprot id: A0A5P2ES28
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

223919:F3K33 RS15910
gene id: 223919:F3K33_RS15910
uniprot id: A0A5P2EYN7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial solute-binding protein 2 family.
messages: Periplasm
messages: The ABC transporter complex is composed of one ATP-binding protein (MglA), two transmembrane proteins (MglC) and a solute-binding protein (MglB).

223919:F3K33 RS15965
gene id: 223919:F3K33_RS15965
uniprot id: A0A5P2EZL2
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

223919:F3K33 RS06340
gene id: 223919:F3K33_RS06340
uniprot id: A0A5P2EUX4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein S19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein S19.

223919:F3K33 RS02645
gene id: 223919:F3K33_RS02645
uniprot id: A0A5P2EPL2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

223919:F3K33 RS23240
gene id: 223919:F3K33_RS23240
uniprot id: A0A5P2F601
names: Subcellular Location Annotation
messages: Cytoplasm

223919:F3K33 RS00615
gene id: 223919:F3K33_RS00615
uniprot id: A0A5P2ENC1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

223919:F3K33 RS04975
gene id: 223919:F3K33_RS04975
uniprot id: A0A5P2ETY0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CobB/CobQ family. GatD subfamily.
messages: Forms a heterodimer with MurT.
messages: The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The GatD subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia. The resulting ammonia molecule is channeled to the active site of MurT.

223919:F3K33 RS20790
gene id: 223919:F3K33_RS20790
uniprot id: A0A5P2EYI6
names: Similarity
messages: Belongs to the EutP/PduV family.

223919:F3K33 RS03910
gene id: 223919:F3K33_RS03910
uniprot id: A0A5P2EQ20
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Homodimer.
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II ManXYZ PTS system is involved in mannose transport.

223919:F3K33 RS02815
gene id: 223919:F3K33_RS02815
uniprot id: A0A5P2EPN8
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

223919:F3K33 RS08420
gene id: 223919:F3K33_RS08420
uniprot id: A0A5P2ESC4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

223919:F3K33 RS18060
gene id: 223919:F3K33_RS18060
uniprot id: A0A5P2EZL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ro 60 kDa family.
messages: Cytoplasm

223919:F3K33 RS19765
gene id: 223919:F3K33_RS19765
uniprot id: A0A5P2F228
names: Subcellular Location Annotation
messages: Cytoplasm

223919:F3K33 RS13455
gene id: 223919:F3K33_RS13455
uniprot id: A0A5P2EUS9
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 4 family.
messages: Binds 1 NAD(+) per subunit.
messages: Homotetramer.

223919:F3K33 RS03215
gene id: 223919:F3K33_RS03215
uniprot id: A0A5P2EPK2
names: Subcellular Location Annotation
messages: Membrane

223919:F3K33 RS24675
gene id: 223919:F3K33_RS24675
uniprot id: A0A5P2F0F4
names: Similarity
messages: Belongs to the antibiotic N-acetyltransferase family.

223919:F3K33 RS01940
gene id: 223919:F3K33_RS01940
uniprot id: A0A5P2ENZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

223919:F3K33 RS11370
gene id: 223919:F3K33_RS11370
uniprot id: A0A5P2EZI7
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

223919:F3K33 RS10390
gene id: 223919:F3K33_RS10390
uniprot id: A0A5P2EX49
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

223919:F3K33 RS22155
gene id: 223919:F3K33_RS22155
uniprot id: A0A5P2F1K9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP-dependent AMP-binding enzyme family. DltA subfamily.
messages: Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP-dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

223919:F3K33 RS18655
gene id: 223919:F3K33_RS18655
uniprot id: A0A5P2EXE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OXA1/ALB3/YidC family.
messages: Membrane

223919:F3K33 RS08185
gene id: 223919:F3K33_RS08185
uniprot id: A0A5P2EUQ8
names: Similarity
messages: Belongs to the transpeptidase family.

223919:F3K33 RS20820
gene id: 223919:F3K33_RS20820
uniprot id: A0A5P2F9L3
names: Similarity
messages: Belongs to the DtxR/MntR family.

223919:F3K33 RS22720
gene id: 223919:F3K33_RS22720
uniprot id: A0A5P2F5R6
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

223919:F3K33 RS13935
gene id: 223919:F3K33_RS13935
uniprot id: A0A5P2EV39
names: Similarity
messages: Belongs to the D-glutamate cyclase family.

223919:F3K33 RS11005
gene id: 223919:F3K33_RS11005
uniprot id: A0A5P2EX60
names: Subcellular Location Annotation
messages: Membrane

223919:F3K33 RS07290
gene id: 223919:F3K33_RS07290
uniprot id: A0A5P2ERH4
names: Similarity
messages: Belongs to the peptidase M18 family.

223919:F3K33 RS23085
gene id: 223919:F3K33_RS23085
uniprot id: A0A5P2EZF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

223919:F3K33 RS12565
gene id: 223919:F3K33_RS12565
uniprot id: A0A5P2EUB4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the KduI family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of 5-dehydro-4-deoxy-D-glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate.

223919:F3K33 RS25805
gene id: 223919:F3K33_RS25805
uniprot id: A0A5P2F120
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

223919:F3K33 RS01060
gene id: 223919:F3K33_RS01060
uniprot id: A0A5P2EZE9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

223919:F3K33 RS21540
gene id: 223919:F3K33_RS21540
uniprot id: A0A5P2F347
names: Subcellular Location Annotation
messages: Membrane

223919:F3K33 RS18860
gene id: 223919:F3K33_RS18860
uniprot id: A0A5P2F3P2
names: Subcellular Location Annotation
messages: Membrane

223919:F3K33 RS23180
gene id: 223919:F3K33_RS23180
uniprot id: A0A5P2FAV8
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane.

223919:F3K33 RS04210
gene id: 223919:F3K33_RS04210
uniprot id: A0A5P2EQA1
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

223919:F3K33 RS21625
gene id: 223919:F3K33_RS21625
uniprot id: A0A5P2EYN0
names: Similarity
messages: Belongs to the IMPACT family.

223919:F3K33 RS06070
gene id: 223919:F3K33_RS06070
uniprot id: A0A5P2ER49
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

223919:F3K33 RS23815
gene id: 223919:F3K33_RS23815
uniprot id: A0A5P2EZU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

223919:F3K33 RS08175
gene id: 223919:F3K33_RS08175
uniprot id: A0A5P2F310
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

223919:F3K33 RS06190
gene id: 223919:F3K33_RS06190
uniprot id: A0A5P2EUU5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Cytoplasm
messages: Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.

223919:F3K33 RS01090
gene id: 223919:F3K33_RS01090
uniprot id: A0A5P2ENJ2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

223919:F3K33 RS11110
gene id: 223919:F3K33_RS11110
uniprot id: A0A5P2ETP2
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

223919:F3K33 RS15110
gene id: 223919:F3K33_RS15110
uniprot id: A0A5P2EVH7
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).

223919:F3K33 RS19320
gene id: 223919:F3K33_RS19320
uniprot id: A0A5P2F8M1
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

223919:F3K33 RS21915
gene id: 223919:F3K33_RS21915
uniprot id: A0A5P2FA91
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

223919:F3K33 RS06585
gene id: 223919:F3K33_RS06585
uniprot id: A0A5P2EUU4
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

223919:F3K33 RS00340
gene id: 223919:F3K33_RS00340
uniprot id: A0A5P2ERM4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

223919:F3K33 RS15820
gene id: 223919:F3K33_RS15820
uniprot id: A0A5P2F6Z8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

223919:F3K33 RS06770
gene id: 223919:F3K33_RS06770
uniprot id: A0A5P2ERK1
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

223919:F3K33 RS21135
gene id: 223919:F3K33_RS21135
uniprot id: A0A5P2F9S6
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

223919:F3K33 RS02260
gene id: 223919:F3K33_RS02260
uniprot id: A0A5P2EP28
names: Function
names: Similarity
messages: Belongs to the peptidase S51 family.
messages: Exopeptidase that catalyzes the hydrolytic cleavage of multi-L-arginyl-poly-L-aspartic acid (cyanophycin; a water-insoluble reserve polymer) into aspartate-arginine dipeptides.

223919:F3K33 RS22865
gene id: 223919:F3K33_RS22865
uniprot id: A0A5P2F2A6
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

223919:F3K33 RS23485
gene id: 223919:F3K33_RS23485
uniprot id: A0A5P2F3D4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetokinase family.
messages: Cytoplasm

223919:F3K33 RS08595
gene id: 223919:F3K33_RS08595
uniprot id: A0A5P2EW29
names: Similarity
messages: Belongs to the UPF0246 family.

223919:F3K33 RS10015
gene id: 223919:F3K33_RS10015
uniprot id: A0A5P2EVN4
names: Similarity
messages: Belongs to the Ahb/Nir family.

223919:F3K33 RS06715
gene id: 223919:F3K33_RS06715
uniprot id: A0A5P2ERF6
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

223919:F3K33 RS25865
gene id: 223919:F3K33_RS25865
uniprot id: A0A5P2F7D1
names: Subcellular Location Annotation
messages: Membrane

223919:F3K33 RS03330
gene id: 223919:F3K33_RS03330
uniprot id: A0A5P2EPW9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

223919:F3K33 RS19230
gene id: 223919:F3K33_RS19230
uniprot id: A0A5P2F3W2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

223919:F3K33 RS12410
gene id: 223919:F3K33_RS12410
uniprot id: A0A5P2EUB2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. Xpt subfamily.
messages: Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.
messages: Cytoplasm
messages: Homodimer.

223919:F3K33 RS01110
gene id: 223919:F3K33_RS01110
uniprot id: A0A5P2EZG0
names: Similarity
messages: Belongs to the class-I fumarase family.

223919:F3K33 RS04005
gene id: 223919:F3K33_RS04005
uniprot id: A0A5P2EVF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

223919:F3K33 RS08295
gene id: 223919:F3K33_RS08295
uniprot id: A0A5P2ES12
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

223919:F3K33 RS24920
gene id: 223919:F3K33_RS24920
uniprot id: A0A5P2F6V3
names: Function
names: Similarity
messages: Belongs to the RapZ-like family.
messages: Displays ATPase and GTPase activities.

223919:F3K33 RS15705
gene id: 223919:F3K33_RS15705
uniprot id: A0A5P2EYK0
names: Similarity
messages: Belongs to the DtxR/MntR family.

223919:F3K33 RS23415
gene id: 223919:F3K33_RS23415
uniprot id: A0A5P2EZX0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

223919:F3K33 RS15020
gene id: 223919:F3K33_RS15020
uniprot id: A0A5P2EZH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CotF family.
messages: Spore coat

223919:F3K33 RS15045
gene id: 223919:F3K33_RS15045
uniprot id: A0A5P2EVR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

223919:F3K33 RS24950
gene id: 223919:F3K33_RS24950
uniprot id: A0A5P2F451
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

223919:F3K33 RS12280
gene id: 223919:F3K33_RS12280
uniprot id: A0A5P2EY36
names: Similarity
messages: Belongs to the peptidase M16 family.

223919:F3K33 RS00905
gene id: 223919:F3K33_RS00905
uniprot id: A0A5P2EZB8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

223919:F3K33 RS13095
gene id: 223919:F3K33_RS13095
uniprot id: A0A5P2EUK7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

223919:F3K33 RS18755
gene id: 223919:F3K33_RS18755
uniprot id: A0A5P2EX57
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

223919:F3K33 RS14320
gene id: 223919:F3K33_RS14320
uniprot id: A0A5P2EV65
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

223919:F3K33 RS00705
gene id: 223919:F3K33_RS00705
uniprot id: A0A5P2EQW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Cell membrane
messages: Membrane

223919:F3K33 RS09125
gene id: 223919:F3K33_RS09125
uniprot id: A0A5P2EWD3
names: Subcellular Location Annotation
messages: Cytoplasm

223919:F3K33 RS25230
gene id: 223919:F3K33_RS25230
uniprot id: A0A5P2FBX2
names: Subcellular Location Annotation
messages: Membrane

223919:F3K33 RS23765
gene id: 223919:F3K33_RS23765
uniprot id: A0A5P2EZT3
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

223919:F3K33 RS23060
gene id: 223919:F3K33_RS23060
uniprot id: A0A5P2F360
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

223919:F3K33 RS06000
gene id: 223919:F3K33_RS06000
uniprot id: A0A5P2EQV7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

223919:F3K33 RS24270
gene id: 223919:F3K33_RS24270
uniprot id: A0A5P2F4L0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

223919:F3K33 RS08560
gene id: 223919:F3K33_RS08560
uniprot id: A0A5P2EY06
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

223919:F3K33 RS08600
gene id: 223919:F3K33_RS08600
uniprot id: A0A5P2F392
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase Z family.
messages: Binds 2 Zn(2+) ions.
messages: Homodimer.
messages: Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.

223919:F3K33 RS12360
gene id: 223919:F3K33_RS12360
uniprot id: A0A5P2EUA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

223919:F3K33 RS15750
gene id: 223919:F3K33_RS15750
uniprot id: A0A5P2EVU2
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

223919:F3K33 RS00970
gene id: 223919:F3K33_RS00970
uniprot id: A0A5P2ENG9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

223919:F3K33 RS06570
gene id: 223919:F3K33_RS06570
uniprot id: A0A5P2ERE8
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

223919:F3K33 RS08105
gene id: 223919:F3K33_RS08105
uniprot id: A0A5P2ES40
names: Similarity
names: Subunit
messages: Belongs to the serine/threonine dehydratase family.
messages: In the native structure, TdcB is in a dimeric form, whereas in the TdcB-AMP complex, it exists in a tetrameric form (dimer of dimers).

223919:F3K33 RS17980
gene id: 223919:F3K33_RS17980
uniprot id: A0A5P2EZQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

223919:F3K33 RS26195
gene id: 223919:F3K33_RS26195
uniprot id: A0A5P2F0Y4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

223919:F3K33 RS07460
gene id: 223919:F3K33_RS07460
uniprot id: A0A5P2EU19
names: Similarity
messages: Belongs to the bacterial solute-binding protein 1 family.

223919:F3K33 RS03505
gene id: 223919:F3K33_RS03505
uniprot id: A0A5P2ET97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

223919:F3K33 RS03475
gene id: 223919:F3K33_RS03475
uniprot id: A0A5P2EPP4
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

223919:F3K33 RS10205
gene id: 223919:F3K33_RS10205
uniprot id: A0A5P2ET84
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ApbE family.
messages: Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.
messages: Magnesium. Can also use manganese.

223919:F3K33 RS24150
gene id: 223919:F3K33_RS24150
uniprot id: A0A5P2F2J6
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

223919:F3K33 RS14835
gene id: 223919:F3K33_RS14835
uniprot id: A0A5P2EY51
names: Function
names: Similarity
messages: Belongs to the transposase 11 family.
messages: Involved in the transposition of the insertion sequence IS5.

223919:F3K33 RS08005
gene id: 223919:F3K33_RS08005
uniprot id: A0A5P2ES23
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

223919:F3K33 RS06600
gene id: 223919:F3K33_RS06600
uniprot id: A0A5P2ETW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

223919:F3K33 RS09260
gene id: 223919:F3K33_RS09260
uniprot id: A0A5P2ESP7
names: Similarity
messages: Belongs to the ThrE exporter (TC 2.A.79) family.

223919:F3K33 RS07095
gene id: 223919:F3K33_RS07095
uniprot id: A0A5P2EV35
names: Similarity
messages: Belongs to the peptidase S16 family.

223919:F3K33 RS21515
gene id: 223919:F3K33_RS21515
uniprot id: A0A5P2EZ48
names: Caution
names: Function
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

223919:F3K33 RS03305
gene id: 223919:F3K33_RS03305
uniprot id: A0A5P2ES64
names: Cofactor
names: Similarity
messages: Belongs to the UPF0313 family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

223919:F3K33 RS00790
gene id: 223919:F3K33_RS00790
uniprot id: A0A5P2ERU4
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.

223919:F3K33 RS19410
gene id: 223919:F3K33_RS19410
uniprot id: A0A5P2F086
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.
messages: May be involved in the biosynthesis of molybdopterin.

223919:F3K33 RS12075
gene id: 223919:F3K33_RS12075
uniprot id: A0A5P2F535
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

223919:F3K33 RS08950
gene id: 223919:F3K33_RS08950
uniprot id: A0A5P2ESJ6
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

223919:F3K33 RS04340
gene id: 223919:F3K33_RS04340
uniprot id: A0A5P2ESN7
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.

223919:F3K33 RS02970
gene id: 223919:F3K33_RS02970
uniprot id: A0A5P2EPL3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MinC family.
messages: Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization.
messages: Interacts with MinD and FtsZ.

223919:F3K33 RS08605
gene id: 223919:F3K33_RS08605
uniprot id: A0A5P2EUY9
names: Domain
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

223919:F3K33 RS14020
gene id: 223919:F3K33_RS14020
uniprot id: A0A5P2F119
names: Similarity
messages: Belongs to the Nudix hydrolase family.

223919:F3K33 RS09585
gene id: 223919:F3K33_RS09585
uniprot id: A0A5P2ESY0
names: Similarity
messages: Belongs to the iron-containing alcohol dehydrogenase family.

223919:F3K33 RS11315
gene id: 223919:F3K33_RS11315
uniprot id: A0A5P2EZH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

223919:F3K33 RS20410
gene id: 223919:F3K33_RS20410
uniprot id: A0A5P2EYI8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial solute-binding protein 2 family.
messages: Periplasm
messages: The ABC transporter complex is composed of one ATP-binding protein (MglA), two transmembrane proteins (MglC) and a solute-binding protein (MglB).

223919:F3K33 RS08975
gene id: 223919:F3K33_RS08975
uniprot id: A0A5P2EWA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Membrane

223919:F3K33 RS00935
gene id: 223919:F3K33_RS00935
uniprot id: A0A5P2ENG2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

223919:F3K33 RS06615
gene id: 223919:F3K33_RS06615
uniprot id: A0A5P2ERD2
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

223919:F3K33 RS04640
gene id: 223919:F3K33_RS04640
uniprot id: A0A5P2FCG5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

223919:F3K33 RS00465
gene id: 223919:F3K33_RS00465
uniprot id: A0A5P2ENA7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

223919:F3K33 RS03730
gene id: 223919:F3K33_RS03730
uniprot id: A0A5P2EU48
names: Cofactor
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.

223919:F3K33 RS20835
gene id: 223919:F3K33_RS20835
uniprot id: A0A5P2EY78
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by fructose 1,6-bisphosphate (FBP).
messages: Belongs to the LDH/MDH superfamily. LDH family.
messages: Catalyzes the conversion of lactate to pyruvate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

223919:F3K33 RS11340
gene id: 223919:F3K33_RS11340
uniprot id: A0A5P2EWD5
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

223919:F3K33 RS21065
gene id: 223919:F3K33_RS21065
uniprot id: A0A5P2F116
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

223919:F3K33 RS12610
gene id: 223919:F3K33_RS12610
uniprot id: A0A5P2EUE8
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

223919:F3K33 RS26210
gene id: 223919:F3K33_RS26210
uniprot id: A0A5P2F183
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

223919:F3K33 RS22920
gene id: 223919:F3K33_RS22920
uniprot id: A0A5P2F5U7
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

223919:F3K33 RS06310
gene id: 223919:F3K33_RS06310
uniprot id: A0A5P2ER07
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

223919:F3K33 RS25630
gene id: 223919:F3K33_RS25630
uniprot id: A0A5P2F1F9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

223919:F3K33 RS07190
gene id: 223919:F3K33_RS07190
uniprot id: A0A5P2ERP3
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

223919:F3K33 RS04295
gene id: 223919:F3K33_RS04295
uniprot id: A0A5P2EVJ9
names: Cofactor
messages: Binds 1 [2Fe-2S] cluster per subunit.

223919:F3K33 RS03555
gene id: 223919:F3K33_RS03555
uniprot id: A0A5P2ETA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

223919:F3K33 RS17755
gene id: 223919:F3K33_RS17755
uniprot id: A0A5P2F0F6
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

223919:F3K33 RS04345
gene id: 223919:F3K33_RS04345
uniprot id: A0A5P2EVK9
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

223919:F3K33 RS21660
gene id: 223919:F3K33_RS21660
uniprot id: A0A5P2FA31
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Cell membrane
messages: Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.
messages: Membrane

223919:F3K33 RS06210
gene id: 223919:F3K33_RS06210
uniprot id: A0A5P2EQZ2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

223919:F3K33 RS05530
gene id: 223919:F3K33_RS05530
uniprot id: A0A5P2EQX3
names: Similarity
messages: Belongs to the SAICAR synthetase family.

223919:F3K33 RS10945
gene id: 223919:F3K33_RS10945
uniprot id: A0A5P2EW74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0053 family.
messages: Membrane

223919:F3K33 RS01155
gene id: 223919:F3K33_RS01155
uniprot id: A0A5P2ES47
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M38 family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Carboxylation allows a single lysine to coordinate two zinc ions.
messages: Catalyzes the hydrolytic cleavage of a subset of L-isoaspartyl (L-beta-aspartyl) dipeptides. Used to degrade proteins damaged by L-isoaspartyl residues formation.
messages: Cytoplasm

223919:F3K33 RS03205
gene id: 223919:F3K33_RS03205
uniprot id: A0A5P2ES45
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

223919:F3K33 RS15265
gene id: 223919:F3K33_RS15265
uniprot id: A0A5P2EVN8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

223919:F3K33 RS18405
gene id: 223919:F3K33_RS18405
uniprot id: A0A5P2EZR9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

223919:F3K33 RS05945
gene id: 223919:F3K33_RS05945
uniprot id: A0A5P2EQU9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
messages: Cytoplasm
messages: Homodimer. Forms a heterotetramer with IscU, interacts with other sulfur acceptors.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.

223919:F3K33 RS13385
gene id: 223919:F3K33_RS13385
uniprot id: A0A5P2EUL3
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

223919:F3K33 RS01255
gene id: 223919:F3K33_RS01255
uniprot id: A0A5P2ENM2
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

223919:F3K33 RS26190
gene id: 223919:F3K33_RS26190
uniprot id: A0A5P2F7I0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

223919:F3K33 RS03355
gene id: 223919:F3K33_RS03355
uniprot id: A0A5P2F0J0
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

223919:F3K33 RS19505
gene id: 223919:F3K33_RS19505
uniprot id: A0A5P2EXJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

223919:F3K33 RS19280
gene id: 223919:F3K33_RS19280
uniprot id: A0A5P2F3X1
names: Subcellular Location Annotation
messages: Membrane

223919:F3K33 RS06490
gene id: 223919:F3K33_RS06490
uniprot id: A0A5P2EV04
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

223919:F3K33 RS00185
gene id: 223919:F3K33_RS00185
uniprot id: A0A5P2ERN6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

223919:F3K33 RS25560
gene id: 223919:F3K33_RS25560
uniprot id: A0A5P2F3W4
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

223919:F3K33 RS01620
gene id: 223919:F3K33_RS01620
uniprot id: A0A5P2ENT6
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

223919:F3K33 RS08435
gene id: 223919:F3K33_RS08435
uniprot id: A0A5P2EVR8
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

223919:F3K33 RS00870
gene id: 223919:F3K33_RS00870
uniprot id: A0A5P2ENF4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

223919:F3K33 RS03965
gene id: 223919:F3K33_RS03965
uniprot id: A0A5P2EQ69
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

223919:F3K33 RS02700
gene id: 223919:F3K33_RS02700
uniprot id: A0A5P2EPA9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia.

223919:F3K33 RS06370
gene id: 223919:F3K33_RS06370
uniprot id: A0A5P2ERB6
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

223919:F3K33 RS03040
gene id: 223919:F3K33_RS03040
uniprot id: A0A5P2ESW9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

223919:F3K33 RS14505
gene id: 223919:F3K33_RS14505
uniprot id: A0A5P2EV89
names: Similarity
messages: Belongs to the peptidase S33 family.

223919:F3K33 RS15840
gene id: 223919:F3K33_RS15840
uniprot id: A0A5P2EW62
names: Similarity
messages: Belongs to the BMP lipoprotein family.

223919:F3K33 RS11010
gene id: 223919:F3K33_RS11010
uniprot id: A0A5P2EXI2
names: Subcellular Location Annotation
messages: Cytoplasm

223919:F3K33 RS23650
gene id: 223919:F3K33_RS23650
uniprot id: A0A5P2FB38
names: Similarity
messages: Belongs to the SIS family. PHI subfamily.

223919:F3K33 RS01165
gene id: 223919:F3K33_RS01165
uniprot id: A0A5P2F484
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the adenylate cyclase family. DacA/CdaA subfamily.
messages: Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably a homodimer.

223919:F3K33 RS05470
gene id: 223919:F3K33_RS05470
uniprot id: A0A5P2EQL3
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

223919:F3K33 RS07020
gene id: 223919:F3K33_RS07020
uniprot id: A0A5P2ERD9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
messages: This function is generally fulfilled by the C-terminal part of HisG, which is missing in some bacteria such as this one.

223919:F3K33 RS04520
gene id: 223919:F3K33_RS04520
uniprot id: A0A5P2EQA8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

223919:F3K33 RS01370
gene id: 223919:F3K33_RS01370
uniprot id: A0A5P2ES83
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

223919:F3K33 RS13825
gene id: 223919:F3K33_RS13825
uniprot id: A0A5P2EUZ5
names: Subcellular Location Annotation
messages: Membrane

223919:F3K33 RS00945
gene id: 223919:F3K33_RS00945
uniprot id: A0A5P2ERX6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

223919:F3K33 RS17735
gene id: 223919:F3K33_RS17735
uniprot id: A0A5P2EX54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

223919:F3K33 RS23520
gene id: 223919:F3K33_RS23520
uniprot id: A0A5P2EZZ0
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

223919:F3K33 RS05900
gene id: 223919:F3K33_RS05900
uniprot id: A0A5P2ER29
names: Similarity
messages: Belongs to the UDPGP type 2 family.

223919:F3K33 RS25500
gene id: 223919:F3K33_RS25500
uniprot id: A0A5P2FC20
names: Function
messages: Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.

223919:F3K33 RS14880
gene id: 223919:F3K33_RS14880
uniprot id: A0A5P2EZF6
names: Similarity
messages: Belongs to the DEAD box helicase family.

223919:F3K33 RS17740
gene id: 223919:F3K33_RS17740
uniprot id: A0A5P2EWX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

223919:F3K33 RS00630
gene id: 223919:F3K33_RS00630
uniprot id: A0A5P2ENC0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

223919:F3K33 RS15155
gene id: 223919:F3K33_RS15155
uniprot id: A0A5P2EVL9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division.

223919:F3K33 RS13295
gene id: 223919:F3K33_RS13295
uniprot id: A0A5P2EUS1
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.

223919:F3K33 RS25780
gene id: 223919:F3K33_RS25780
uniprot id: A0A5P2F408
names: Similarity
messages: Belongs to the P(II) protein family.

223919:F3K33 RS05220
gene id: 223919:F3K33_RS05220
uniprot id: A0A5P2EQP6
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

223919:F3K33 RS06465
gene id: 223919:F3K33_RS06465
uniprot id: A0A5P2ERA6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

223919:F3K33 RS02340
gene id: 223919:F3K33_RS02340
uniprot id: A0A5P2EUJ9
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

223919:F3K33 RS01070
gene id: 223919:F3K33_RS01070
uniprot id: A0A5P2ETY1
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

223919:F3K33 RS00405
gene id: 223919:F3K33_RS00405
uniprot id: A0A5P2EQT5
names: Function
names: Similarity
messages: Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Belongs to the organic radical-activating enzymes family.

223919:F3K33 RS03200
gene id: 223919:F3K33_RS03200
uniprot id: A0A5P2F0G1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AP endonuclease 2 family.
messages: Binds 3 Zn(2+) ions.
messages: Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.

223919:F3K33 RS13725
gene id: 223919:F3K33_RS13725
uniprot id: A0A5P2EUX8
names: Subcellular Location Annotation
messages: Membrane

223919:F3K33 RS07230
gene id: 223919:F3K33_RS07230
uniprot id: A0A5P2ERG5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

223919:F3K33 RS20970
gene id: 223919:F3K33_RS20970
uniprot id: A0A5P2F2T9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

223919:F3K33 RS17060
gene id: 223919:F3K33_RS17060
uniprot id: A0A5P2F2T7
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

223919:F3K33 RS21195
gene id: 223919:F3K33_RS21195
uniprot id: A0A5P2F4W6
names: Subcellular Location Annotation
messages: Membrane

223919:F3K33 RS07080
gene id: 223919:F3K33_RS07080
uniprot id: A0A5P2ERQ6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

223919:F3K33 RS03290
gene id: 223919:F3K33_RS03290
uniprot id: A0A5P2ET17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

223919:F3K33 RS06030
gene id: 223919:F3K33_RS06030
uniprot id: A0A5P2EUI9
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

223919:F3K33 RS05500
gene id: 223919:F3K33_RS05500
uniprot id: A0A5P2EUG2
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

223919:F3K33 RS25945
gene id: 223919:F3K33_RS25945
uniprot id: A0A5P2F4M1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

223919:F3K33 RS22145
gene id: 223919:F3K33_RS22145
uniprot id: A0A5P2EZ92
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-DCP.
messages: Belongs to the DltC family.
messages: Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall.
messages: Cytoplasm

223919:F3K33 RS07805
gene id: 223919:F3K33_RS07805
uniprot id: A0A5P2EU78
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CotF family.
messages: Spore coat

223919:F3K33 RS16890
gene id: 223919:F3K33_RS16890
uniprot id: A0A5P2EZ65
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

223919:F3K33 RS08010
gene id: 223919:F3K33_RS08010
uniprot id: A0A5P2EUC2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

223919:F3K33 RS05260
gene id: 223919:F3K33_RS05260
uniprot id: A0A5P2EQP5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

223919:F3K33 RS19595
gene id: 223919:F3K33_RS19595
uniprot id: A0A5P2F200
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

223919:F3K33 RS02925
gene id: 223919:F3K33_RS02925
uniprot id: A0A5P2EPQ5
names: Similarity
messages: Belongs to the peptidase C40 family.

223919:F3K33 RS05055
gene id: 223919:F3K33_RS05055
uniprot id: A0A5P2EQL2
names: Subcellular Location Annotation
messages: Membrane

223919:F3K33 RS00005
gene id: 223919:F3K33_RS00005
uniprot id: A0A5P2EN47
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

223919:F3K33 RS06230
gene id: 223919:F3K33_RS06230
uniprot id: A0A5P2ETC0
names: Similarity
messages: Belongs to the asp23 family.

223919:F3K33 RS11855
gene id: 223919:F3K33_RS11855
uniprot id: A0A5P2ETX9
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

223919:F3K33 RS08535
gene id: 223919:F3K33_RS08535
uniprot id: A0A5P2EUM3
names: Subcellular Location Annotation
messages: Membrane

223919:F3K33 RS06110
gene id: 223919:F3K33_RS06110
uniprot id: A0A5P2ER46
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

223919:F3K33 RS01235
gene id: 223919:F3K33_RS01235
uniprot id: A0A5P2EU16
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

223919:F3K33 RS06360
gene id: 223919:F3K33_RS06360
uniprot id: A0A5P2ER17
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

223919:F3K33 RS06265
gene id: 223919:F3K33_RS06265
uniprot id: A0A5P2ER71
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TmcAL family.
messages: Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of elongator tRNA(Met), using acetate and ATP as substrates. First activates an acetate ion to form acetyladenylate (Ac-AMP) and then transfers the acetyl group to tRNA to form ac(4)C34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

223919:F3K33 RS14620
gene id: 223919:F3K33_RS14620
uniprot id: A0A5P2EY24
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

223919:F3K33 RS07540
gene id: 223919:F3K33_RS07540
uniprot id: A0A5P2ERM5
names: Similarity
messages: Belongs to the peptidase S8 family.

223919:F3K33 RS20550
gene id: 223919:F3K33_RS20550
uniprot id: A0A5P2F135
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

223919:F3K33 RS12790
gene id: 223919:F3K33_RS12790
uniprot id: A0A5P2EXZ3
names: Similarity
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.

223919:F3K33 RS08795
gene id: 223919:F3K33_RS08795
uniprot id: A0A5P2ESG7
names: Similarity
messages: Belongs to the UPF0111 family.

223919:F3K33 RS22650
gene id: 223919:F3K33_RS22650
uniprot id: A0A5P2F3Q8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the galactose-1-phosphate uridylyltransferase type 2 family.
messages: Cytoplasm

223919:F3K33 RS01705
gene id: 223919:F3K33_RS01705
uniprot id: A0A5P2ENV0
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.

223919:F3K33 RS23620
gene id: 223919:F3K33_RS23620
uniprot id: A0A5P2F0A5
names: Cofactor
messages: Binds 1 Mg(2+) ion per trimer.

223919:F3K33 RS20175
gene id: 223919:F3K33_RS20175
uniprot id: A0A5P2F994
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

223919:F3K33 RS01430
gene id: 223919:F3K33_RS01430
uniprot id: A0A5P2ERA2
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

223919:F3K33 RS21090
gene id: 223919:F3K33_RS21090
uniprot id: A0A5P2F1D3
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

223919:F3K33 RS02370
gene id: 223919:F3K33_RS02370
uniprot id: A0A5P2ESL1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

223919:F3K33 RS06315
gene id: 223919:F3K33_RS06315
uniprot id: A0A5P2ER81
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

223919:F3K33 RS15745
gene id: 223919:F3K33_RS15745
uniprot id: A0A5P2EVY5
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

223919:F3K33 RS06270
gene id: 223919:F3K33_RS06270
uniprot id: A0A5P2ER98
names: Similarity
messages: Belongs to the phosphate acetyltransferase and butyryltransferase family.

223919:F3K33 RS19040
gene id: 223919:F3K33_RS19040
uniprot id: A0A5P2EXE9
names: Similarity
messages: Belongs to the glycosyl hydrolase 25 family.

223919:F3K33 RS25460
gene id: 223919:F3K33_RS25460
uniprot id: A0A5P2F0L6
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

223919:F3K33 RS10325
gene id: 223919:F3K33_RS10325
uniprot id: A0A5P2EVU6
names: Similarity
messages: Belongs to the manganese catalase family.

223919:F3K33 RS02960
gene id: 223919:F3K33_RS02960
uniprot id: A0A5P2EUV9
names: Similarity
messages: Belongs to the transpeptidase family.

223919:F3K33 RS07360
gene id: 223919:F3K33_RS07360
uniprot id: A0A5P2ETZ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

223919:F3K33 RS08430
gene id: 223919:F3K33_RS08430
uniprot id: A0A5P2EUK2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

223919:F3K33 RS12355
gene id: 223919:F3K33_RS12355
uniprot id: A0A5P2EU87
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

223919:F3K33 RS22290
gene id: 223919:F3K33_RS22290
uniprot id: A0A5P2EZK5
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 4 family.
messages: Binds 1 NAD(+) per subunit.
messages: Homotetramer.

223919:F3K33 RS26170
gene id: 223919:F3K33_RS26170
uniprot id: A0A5P2F4R0
names: Similarity
messages: Belongs to the ParB family.

223919:F3K33 RS05615
gene id: 223919:F3K33_RS05615
uniprot id: A0A5P2ETE3
names: Similarity
messages: Belongs to the fabD family.

223919:F3K33 RS25650
gene id: 223919:F3K33_RS25650
uniprot id: A0A5P2F4H0
names: Subcellular Location Annotation
messages: Membrane

223919:F3K33 RS11875
gene id: 223919:F3K33_RS11875
uniprot id: A0A5P2F4Z9
names: Subcellular Location Annotation
messages: Membrane

223919:F3K33 RS10135
gene id: 223919:F3K33_RS10135
uniprot id: A0A5P2EYU0
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase family.

223919:F3K33 RS10370
gene id: 223919:F3K33_RS10370
uniprot id: A0A5P2ET90
names: Similarity
messages: Belongs to the NAPRTase family.

223919:F3K33 RS00410
gene id: 223919:F3K33_RS00410
uniprot id: A0A5P2ETL8
names: Similarity
messages: Belongs to the DNA glycosylase MPG family.

223919:F3K33 RS05645
gene id: 223919:F3K33_RS05645
uniprot id: A0A5P2ET19
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

223919:F3K33 RS20490
gene id: 223919:F3K33_RS20490
uniprot id: A0A5P2F9F2
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

223919:F3K33 RS02625
gene id: 223919:F3K33_RS02625
uniprot id: A0A5P2ERT1
names: Cofactor
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Binds 1 Fe(3+) ion per subunit.

223919:F3K33 RS23685
gene id: 223919:F3K33_RS23685
uniprot id: A0A5P2F2B6
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

223919:F3K33 RS26130
gene id: 223919:F3K33_RS26130
uniprot id: A0A5P2F7H0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

223919:F3K33 RS08680
gene id: 223919:F3K33_RS08680
uniprot id: A0A5P2ESH3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

223919:F3K33 RS00815
gene id: 223919:F3K33_RS00815
uniprot id: A0A5P2ENE4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

223919:F3K33 RS12625
gene id: 223919:F3K33_RS12625
uniprot id: A0A5P2EXW9
names: Function
names: Similarity
messages: Belongs to the alpha/beta-type SASP family.
messages: SASP are bound to spore DNA. They are double-stranded DNA-binding proteins that cause DNA to change to an a-like conformation. They protect the DNA backbone from chemical and enzymatic cleavage and are thus involved in dormant spore's high resistance to UV light.

223919:F3K33 RS20305
gene id: 223919:F3K33_RS20305
uniprot id: A0A5P2EXY4
names: Similarity
messages: Belongs to the shaker potassium channel beta subunit family.

223919:F3K33 RS19500
gene id: 223919:F3K33_RS19500
uniprot id: A0A5P2F407
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

223919:F3K33 RS06350
gene id: 223919:F3K33_RS06350
uniprot id: A0A5P2ETS0
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

223919:F3K33 RS05555
gene id: 223919:F3K33_RS05555
uniprot id: A0A5P2F1Q5
names: Similarity
messages: Belongs to the GARS family.

223919:F3K33 RS09510
gene id: 223919:F3K33_RS09510
uniprot id: A0A5P2EVE3
names: Subcellular Location Annotation
messages: Membrane

223919:F3K33 RS21620
gene id: 223919:F3K33_RS21620
uniprot id: A0A5P2F556
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

223919:F3K33 RS24125
gene id: 223919:F3K33_RS24125
uniprot id: A0A5P2F6G3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

223919:F3K33 RS05145
gene id: 223919:F3K33_RS05145
uniprot id: A0A5P2ET48
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

223919:F3K33 RS16195
gene id: 223919:F3K33_RS16195
uniprot id: A0A5P2EZQ4
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.

223919:F3K33 RS14815
gene id: 223919:F3K33_RS14815
uniprot id: A0A5P2EY53
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

223919:F3K33 RS11275
gene id: 223919:F3K33_RS11275
uniprot id: A0A5P2ETS2
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

223919:F3K33 RS06625
gene id: 223919:F3K33_RS06625
uniprot id: A0A5P2ERF7
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

223919:F3K33 RS15765
gene id: 223919:F3K33_RS15765
uniprot id: A0A5P2EZX6
names: Subcellular Location Annotation
messages: Membrane

223919:F3K33 RS23005
gene id: 223919:F3K33_RS23005
uniprot id: A0A5P2F574
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ApbE family.
messages: Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.
messages: Magnesium. Can also use manganese.

223919:F3K33 RS01200
gene id: 223919:F3K33_RS01200
uniprot id: A0A5P2ENL3
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.
messages: In the N-terminal section; belongs to the DHNA family.

223919:F3K33 RS23030
gene id: 223919:F3K33_RS23030
uniprot id: A0A5P2F5W8
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

223919:F3K33 RS20945
gene id: 223919:F3K33_RS20945
uniprot id: A0A5P2EYT9
names: Subcellular Location Annotation
messages: Membrane

223919:F3K33 RS20555
gene id: 223919:F3K33_RS20555
uniprot id: A0A5P2F4J5
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

223919:F3K33 RS08275
gene id: 223919:F3K33_RS08275
uniprot id: A0A5P2EVW5
names: Function
names: Similarity
names: Subunit
messages: Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
messages: Homodimer and homohexamer; in equilibrium.
messages: Regulates transcriptional attenuation of the pyrimidine nucleotide (pyr) operon by binding in a uridine-dependent manner to specific sites on pyr mRNA. This disrupts an antiterminator hairpin in the RNA and favors formation of a downstream transcription terminator, leading to a reduced expression of downstream genes.

223919:F3K33 RS21235
gene id: 223919:F3K33_RS21235
uniprot id: A0A5P2F9U7
names: Similarity
messages: Belongs to the ClpA/ClpB family.

223919:F3K33 RS08590
gene id: 223919:F3K33_RS08590
uniprot id: A0A5P2EVU8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
messages: Belongs to the azoreductase type 1 family.
messages: Binds 1 FMN per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones.

223919:F3K33 RS21375
gene id: 223919:F3K33_RS21375
uniprot id: A0A5P2F294
names: Subcellular Location Annotation
messages: Membrane

223919:F3K33 RS12575
gene id: 223919:F3K33_RS12575
uniprot id: A0A5P2EXW0
names: Caution
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

223919:F3K33 RS05050
gene id: 223919:F3K33_RS05050
uniprot id: A0A5P2EQE3
names: Subcellular Location Annotation
messages: Membrane

223919:F3K33 RS08205
gene id: 223919:F3K33_RS08205
uniprot id: A0A5P2ES90
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

223919:F3K33 RS09820
gene id: 223919:F3K33_RS09820
uniprot id: A0A5P2ET05
names: Similarity
messages: Belongs to the carbamate kinase family.

223919:F3K33 RS01980
gene id: 223919:F3K33_RS01980
uniprot id: A0A5P2EP74
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

223919:F3K33 RS17005
gene id: 223919:F3K33_RS17005
uniprot id: A0A5P2EZ83
names: Function
names: Similarity
messages: Belongs to the desulfoferrodoxin family.
messages: Catalyzes the one-electron reduction of superoxide anion radical to hydrogen peroxide at a nonheme ferrous iron center. Plays a fundamental role in case of oxidative stress via its superoxide detoxification activity.

223919:F3K33 RS01975
gene id: 223919:F3K33_RS01975
uniprot id: A0A5P2ENZ9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

223919:F3K33 RS09780
gene id: 223919:F3K33_RS09780
uniprot id: A0A5P2ESY8
names: Function
names: Similarity
messages: Belongs to the 'phage' integrase family.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.

223919:F3K33 RS12930
gene id: 223919:F3K33_RS12930
uniprot id: A0A5P2EUI5
names: Similarity
messages: Belongs to the peptidase S66 family.

223919:F3K33 RS23335
gene id: 223919:F3K33_RS23335
uniprot id: A0A5P2F2I8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

223919:F3K33 RS15030
gene id: 223919:F3K33_RS15030
uniprot id: A0A5P2EY79
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

223919:F3K33 RS14040
gene id: 223919:F3K33_RS14040
uniprot id: A0A5P2EV57
names: Similarity
messages: Belongs to the flavin oxidoreductase frp family.

223919:F3K33 RS24655
gene id: 223919:F3K33_RS24655
uniprot id: A0A5P2F6R3
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

223919:F3K33 RS05265
gene id: 223919:F3K33_RS05265
uniprot id: A0A5P2EQR9
names: Similarity
messages: Belongs to the OMP decarboxylase family. Type 2 subfamily.

223919:F3K33 RS11625
gene id: 223919:F3K33_RS11625
uniprot id: A0A5P2EZN0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

223919:F3K33 RS15390
gene id: 223919:F3K33_RS15390
uniprot id: A0A5P2EZ96
names: Similarity
messages: In the N-terminal section; belongs to the zinc metallo-hydrolase group 3 family.

223919:F3K33 RS13795
gene id: 223919:F3K33_RS13795
uniprot id: A0A5P2EYH1
names: Similarity
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

223919:F3K33 RS08090
gene id: 223919:F3K33_RS08090
uniprot id: A0A5P2ERW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uridine kinase family.
messages: Cytoplasm

223919:F3K33 RS10895
gene id: 223919:F3K33_RS10895
uniprot id: A0A5P2EW66
names: Cofactor
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.

223919:F3K33 RS00855
gene id: 223919:F3K33_RS00855
uniprot id: A0A5P2EZA8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

223919:F3K33 RS13090
gene id: 223919:F3K33_RS13090
uniprot id: A0A5P2EUN5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

223919:F3K33 RS10210
gene id: 223919:F3K33_RS10210
uniprot id: A0A5P2ET62
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

223919:F3K33 RS02575
gene id: 223919:F3K33_RS02575
uniprot id: A0A5P2ERS0
names: Similarity
messages: Belongs to the glutamine synthetase family.

223919:F3K33 RS15850
gene id: 223919:F3K33_RS15850
uniprot id: A0A5P2EVV9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

223919:F3K33 RS14860
gene id: 223919:F3K33_RS14860
uniprot id: A0A5P2EVE1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

223919:F3K33 RS24210
gene id: 223919:F3K33_RS24210
uniprot id: A0A5P2F2K6
names: Similarity
messages: Belongs to the peptidase C40 family.

223919:F3K33 RS12655
gene id: 223919:F3K33_RS12655
uniprot id: A0A5P2EUE3
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

223919:F3K33 RS23850
gene id: 223919:F3K33_RS23850
uniprot id: A0A5P2FB75
names: Cofactor
messages: Binds 1 Mg(2+) ion per trimer.

223919:F3K33 RS13460
gene id: 223919:F3K33_RS13460
uniprot id: A0A5P2EXG6
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane.

223919:F3K33 RS21080
gene id: 223919:F3K33_RS21080
uniprot id: A0A5P2F2V7
names: Similarity
messages: Belongs to the CFA/CMAS family.

223919:F3K33 RS10110
gene id: 223919:F3K33_RS10110
uniprot id: A0A5P2EQN1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

223919:F3K33 RS03815
gene id: 223919:F3K33_RS03815
uniprot id: A0A5P2EPV9
names: Subcellular Location Annotation
messages: Membrane

223919:F3K33 RS13535
gene id: 223919:F3K33_RS13535
uniprot id: A0A5P2F0S0
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the peroxiredoxin family. Tpx subfamily.
messages: Homodimer.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. In this atypical 2-Cys peroxiredoxin, C(R) is present in the same subunit to form an intramolecular disulfide. The disulfide is subsequently reduced by thioredoxin.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

223919:F3K33 RS24505
gene id: 223919:F3K33_RS24505
uniprot id: A0A5P2F0S9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

223919:F3K33 RS01950
gene id: 223919:F3K33_RS01950
uniprot id: A0A5P2ESF0
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

223919:F3K33 RS06180
gene id: 223919:F3K33_RS06180
uniprot id: A0A5P2ETB0
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

223919:F3K33 RS03455
gene id: 223919:F3K33_RS03455
uniprot id: A0A5P2F0L2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

223919:F3K33 RS23385
gene id: 223919:F3K33_RS23385
uniprot id: A0A5P2FAZ2
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

223919:F3K33 RS13450
gene id: 223919:F3K33_RS13450
uniprot id: A0A5P2EUV1
names: Cofactor
messages: Binds 1 Mg(2+) ion per trimer.

223919:F3K33 RS05635
gene id: 223919:F3K33_RS05635
uniprot id: A0A5P2EQZ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

223919:F3K33 RS12505
gene id: 223919:F3K33_RS12505
uniprot id: A0A5P2EUB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

223919:F3K33 RS13110
gene id: 223919:F3K33_RS13110
uniprot id: A0A5P2EYI3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L/F-transferase family.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.

223919:F3K33 RS15180
gene id: 223919:F3K33_RS15180
uniprot id: A0A5P2EZ56
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

223919:F3K33 RS14530
gene id: 223919:F3K33_RS14530
uniprot id: A0A5P2EXZ9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

223919:F3K33 RS00780
gene id: 223919:F3K33_RS00780
uniprot id: A0A5P2END9
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

223919:F3K33 RS20860
gene id: 223919:F3K33_RS20860
uniprot id: A0A5P2F1Y4
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

223919:F3K33 RS25920
gene id: 223919:F3K33_RS25920
uniprot id: A0A5P2F0U7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

223919:F3K33 RS02950
gene id: 223919:F3K33_RS02950
uniprot id: A0A5P2F0B1
names: Function
names: Similarity
messages: Belongs to the MreC family.
messages: Involved in formation and maintenance of cell shape.

223919:F3K33 RS01230
gene id: 223919:F3K33_RS01230
uniprot id: A0A5P2ER64
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

223919:F3K33 RS15340
gene id: 223919:F3K33_RS15340
uniprot id: A0A5P2EZ87
names: Similarity
messages: Belongs to the HypD family.

223919:F3K33 RS16780
gene id: 223919:F3K33_RS16780
uniprot id: A0A5P2F2N6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial solute-binding protein 2 family.
messages: Periplasm
messages: The ABC transporter complex is composed of one ATP-binding protein (MglA), two transmembrane proteins (MglC) and a solute-binding protein (MglB).

223919:F3K33 RS15735
gene id: 223919:F3K33_RS15735
uniprot id: A0A5P2EVQ3
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

223919:F3K33 RS02685
gene id: 223919:F3K33_RS02685
uniprot id: A0A5P2F064
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

223919:F3K33 RS18055
gene id: 223919:F3K33_RS18055
uniprot id: A0A5P2EWW7
names: Cofactor
names: Similarity
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.

223919:F3K33 RS05660
gene id: 223919:F3K33_RS05660
uniprot id: A0A5P2F1R9
names: Function
names: Similarity
names: Subunit
messages: Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization.
messages: Belongs to the HutP family.
messages: Homohexamer.

223919:F3K33 RS03575
gene id: 223919:F3K33_RS03575
uniprot id: A0A5P2EPQ8
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

223919:F3K33 RS26180
gene id: 223919:F3K33_RS26180
uniprot id: A0A5P2FCD6
names: Similarity
messages: Belongs to the ParB family.

223919:F3K33 RS12285
gene id: 223919:F3K33_RS12285
uniprot id: A0A5P2F570
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

223919:F3K33 RS00895
gene id: 223919:F3K33_RS00895
uniprot id: A0A5P2ERW6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

223919:F3K33 RS21180
gene id: 223919:F3K33_RS21180
uniprot id: A0A5P2F2X7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/UDP phosphorylase family.
messages: Catalyzes the reversible phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
messages: Homohexamer; trimer of homodimers.

223919:F3K33 RS15830
gene id: 223919:F3K33_RS15830
uniprot id: A0A5P2F256
names: Subcellular Location Annotation
messages: Membrane

223919:F3K33 RS23145
gene id: 223919:F3K33_RS23145
uniprot id: A0A5P2EZG7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

223919:F3K33 RS01895
gene id: 223919:F3K33_RS01895
uniprot id: A0A5P2EQS4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

223919:F3K33 RS16760
gene id: 223919:F3K33_RS16760
uniprot id: A0A5P2ET81
names: Function
names: Similarity
messages: Belongs to the transposase 11 family.
messages: Involved in the transposition of the insertion sequence IS5.

223919:F3K33 RS25515
gene id: 223919:F3K33_RS25515
uniprot id: A0A5P2F0M7
names: Subcellular Location Annotation
messages: Membrane

223919:F3K33 RS05200
gene id: 223919:F3K33_RS05200
uniprot id: A0A5P2EW23
names: Subcellular Location Annotation
messages: Membrane

223919:F3K33 RS15245
gene id: 223919:F3K33_RS15245
uniprot id: A0A5P2EYC0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

223919:F3K33 RS11835
gene id: 223919:F3K33_RS11835
uniprot id: A0A5P2EZR1
names: Function
names: Similarity
messages: Belongs to the CbiD family.
messages: Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.

223919:F3K33 RS08000
gene id: 223919:F3K33_RS08000
uniprot id: A0A5P2ES56
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

223919:F3K33 RS07010
gene id: 223919:F3K33_RS07010
uniprot id: A0A5P2EU42
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThiI family.
messages: Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
messages: Cytoplasm

223919:F3K33 RS00850
gene id: 223919:F3K33_RS00850
uniprot id: A0A5P2ERY6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

223919:F3K33 RS17575
gene id: 223919:F3K33_RS17575
uniprot id: A0A5P2EWN4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

223919:F3K33 RS09115
gene id: 223919:F3K33_RS09115
uniprot id: A0A5P2EUY8
names: Similarity
messages: Belongs to the mannitol dehydrogenase family. UxaB subfamily.

223919:F3K33 RS01095
gene id: 223919:F3K33_RS01095
uniprot id: A0A5P2EQD3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

223919:F3K33 RS04945
gene id: 223919:F3K33_RS04945
uniprot id: A0A5P2EVX1
names: Subcellular Location Annotation
messages: Membrane

223919:F3K33 RS07470
gene id: 223919:F3K33_RS07470
uniprot id: A0A5P2EVH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

223919:F3K33 RS05280
gene id: 223919:F3K33_RS05280
uniprot id: A0A5P2EU41
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

223919:F3K33 RS21150
gene id: 223919:F3K33_RS21150
uniprot id: A0A5P2EYD6
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

223919:F3K33 RS00275
gene id: 223919:F3K33_RS00275
uniprot id: A0A5P2ENL8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

223919:F3K33 RS23945
gene id: 223919:F3K33_RS23945
uniprot id: A0A5P2F3L7
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 4 family.
messages: Binds 1 NAD(+) per subunit.
messages: Homotetramer.

223919:F3K33 RS24410
gene id: 223919:F3K33_RS24410
uniprot id: A0A5P2F0A6
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

223919:F3K33 RS23275
gene id: 223919:F3K33_RS23275
uniprot id: A0A5P2F425
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

223919:F3K33 RS12445
gene id: 223919:F3K33_RS12445
uniprot id: A0A5P2F035
names: Similarity
messages: Belongs to the peptidase C40 family.

223919:F3K33 RS11100
gene id: 223919:F3K33_RS11100
uniprot id: A0A5P2ETG7
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

223919:F3K33 RS00820
gene id: 223919:F3K33_RS00820
uniprot id: A0A5P2ENN6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MrnC RNase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc); Rnc processes 30S rRNA into smaller rRNA precursors.

223919:F3K33 RS13055
gene id: 223919:F3K33_RS13055
uniprot id: A0A5P2EY38
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

223919:F3K33 RS03560
gene id: 223919:F3K33_RS03560
uniprot id: A0A5P2F0N3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nlpA lipoprotein family.
messages: Membrane

223919:F3K33 RS11425
gene id: 223919:F3K33_RS11425
uniprot id: A0A5P2EZJ8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

223919:F3K33 RS25930
gene id: 223919:F3K33_RS25930
uniprot id: A0A5P2F171
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

223919:F3K33 RS22950
gene id: 223919:F3K33_RS22950
uniprot id: A0A5P2F337
names: Similarity
messages: In the N-terminal section; belongs to the zinc metallo-hydrolase group 3 family.

223919:F3K33 RS03985
gene id: 223919:F3K33_RS03985
uniprot id: A0A5P2ETE2
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

223919:F3K33 RS08320
gene id: 223919:F3K33_RS08320
uniprot id: A0A5P2EUI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

223919:F3K33 RS11210
gene id: 223919:F3K33_RS11210
uniprot id: A0A5P2ETI7
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

223919:F3K33 RS15570
gene id: 223919:F3K33_RS15570
uniprot id: A0A5P2EYI5
names: Similarity
messages: Belongs to the pirin family.

223919:F3K33 RS22980
gene id: 223919:F3K33_RS22980
uniprot id: A0A5P2EZY6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

223919:F3K33 RS23105
gene id: 223919:F3K33_RS23105
uniprot id: A0A5P2EZL3
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

223919:F3K33 RS09815
gene id: 223919:F3K33_RS09815
uniprot id: A0A5P2EST6
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily.

223919:F3K33 RS01570
gene id: 223919:F3K33_RS01570
uniprot id: A0A5P2EQM1
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

223919:F3K33 RS10810
gene id: 223919:F3K33_RS10810
uniprot id: A0A5P2EW50
names: Similarity
messages: Belongs to the hemerythrin family.

223919:F3K33 RS22870
gene id: 223919:F3K33_RS22870
uniprot id: A0A5P2F5U0
names: Similarity
messages: Belongs to the aldose epimerase family.

223919:F3K33 RS01615
gene id: 223919:F3K33_RS01615
uniprot id: A0A5P2EP73
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transcriptional regulatory Rex family.
messages: Cytoplasm
messages: Homodimer.
messages: Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.

223919:F3K33 RS13970
gene id: 223919:F3K33_RS13970
uniprot id: A0A5P2F108
names: Subcellular Location Annotation
messages: Membrane

223919:F3K33 RS07465
gene id: 223919:F3K33_RS07465
uniprot id: A0A5P2EV94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

223919:F3K33 RS20615
gene id: 223919:F3K33_RS20615
uniprot id: A0A5P2EYM7
names: Subcellular Location Annotation
messages: Membrane

223919:F3K33 RS09920
gene id: 223919:F3K33_RS09920
uniprot id: A0A5P2ESV6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

223919:F3K33 RS15145
gene id: 223919:F3K33_RS15145
uniprot id: A0A5P2EVE8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

223919:F3K33 RS03805
gene id: 223919:F3K33_RS03805
uniprot id: A0A5P2EQ01
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

223919:F3K33 RS13925
gene id: 223919:F3K33_RS13925
uniprot id: A0A5P2EUW5
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

223919:F3K33 RS05580
gene id: 223919:F3K33_RS05580
uniprot id: A0A5P2EQY1
names: Similarity
messages: Belongs to the HepT RNase toxin family.

223919:F3K33 RS08470
gene id: 223919:F3K33_RS08470
uniprot id: A0A5P2ESD6
names: Cofactor
names: Function
names: Subcellular Location Annotation
messages: Binds 1 Ca(2+) ion per subunit.
messages: Cytoplasm
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

223919:F3K33 RS14550
gene id: 223919:F3K33_RS14550
uniprot id: A0A5P2EVI2
names: Similarity
messages: Belongs to the ABC transporter superfamily.

223919:F3K33 RS05105
gene id: 223919:F3K33_RS05105
uniprot id: A0A5P2EQF2
names: Subcellular Location Annotation
messages: Membrane

223919:F3K33 RS09300
gene id: 223919:F3K33_RS09300
uniprot id: A0A5P2ESJ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ScpB family.
messages: Cytoplasm
messages: Homodimer. Homodimerization may be required to stabilize the binding of ScpA to the Smc head domains. Component of a cohesin-like complex composed of ScpA, ScpB and the Smc homodimer, in which ScpA and ScpB bind to the head domain of Smc. The presence of the three proteins is required for the association of the complex with DNA.
messages: Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves.

223919:F3K33 RS04470
gene id: 223919:F3K33_RS04470
uniprot id: A0A5P2EQ97
names: Subcellular Location Annotation
messages: Membrane

223919:F3K33 RS04205
gene id: 223919:F3K33_RS04205
uniprot id: A0A5P2EQ67
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

223919:F3K33 RS25125
gene id: 223919:F3K33_RS25125
uniprot id: A0A5P2FBW5
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

223919:F3K33 RS24385
gene id: 223919:F3K33_RS24385
uniprot id: A0A5P2F373
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

223919:F3K33 RS07610
gene id: 223919:F3K33_RS07610
uniprot id: A0A5P2ERW4
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

223919:F3K33 RS09985
gene id: 223919:F3K33_RS09985
uniprot id: A0A5P2ET47
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NifD/NifK/NifE/NifN family.
messages: Binds 1 [8Fe-7S] cluster per heterodimer.
messages: Tetramer of two alpha and two beta chains. Forms complex with the iron protein (nitrogenase component 2).
messages: This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation.

223919:F3K33 RS03065
gene id: 223919:F3K33_RS03065
uniprot id: A0A5P2EPH6
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

223919:F3K33 RS03335
gene id: 223919:F3K33_RS03335
uniprot id: A0A5P2EPL7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

223919:F3K33 RS07890
gene id: 223919:F3K33_RS07890
uniprot id: A0A5P2ES11
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

223919:F3K33 RS06130
gene id: 223919:F3K33_RS06130
uniprot id: A0A5P2EUK8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

223919:F3K33 RS06165
gene id: 223919:F3K33_RS06165
uniprot id: A0A5P2ER77
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

223919:F3K33 RS09285
gene id: 223919:F3K33_RS09285
uniprot id: A0A5P2EVA1
names: Caution
names: Function
names: Similarity
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

223919:F3K33 RS02580
gene id: 223919:F3K33_RS02580
uniprot id: A0A5P2EUN8
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

223919:F3K33 RS12990
gene id: 223919:F3K33_RS12990
uniprot id: A0A5P2EUL1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
messages: Cytoplasm

223919:F3K33 RS21740
gene id: 223919:F3K33_RS21740
uniprot id: A0A5P2EZ11
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

223919:F3K33 RS03500
gene id: 223919:F3K33_RS03500
uniprot id: A0A5P2ET56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

223919:F3K33 RS15160
gene id: 223919:F3K33_RS15160
uniprot id: A0A5P2EVI7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation.

223919:F3K33 RS07490
gene id: 223919:F3K33_RS07490
uniprot id: A0A5P2ERL6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

223919:F3K33 RS01225
gene id: 223919:F3K33_RS01225
uniprot id: A0A5P2EZI0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

223919:F3K33 RS02160
gene id: 223919:F3K33_RS02160
uniprot id: A0A5P2EP10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LTA synthase family.
messages: Cell membrane
messages: Membrane

223919:F3K33 RS01065
gene id: 223919:F3K33_RS01065
uniprot id: A0A5P2ER37
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

223919:F3K33 RS15220
gene id: 223919:F3K33_RS15220
uniprot id: A0A5P2EVJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit D family.
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

223919:F3K33 RS15370
gene id: 223919:F3K33_RS15370
uniprot id: A0A5P2EVX3
names: Similarity
names: Subunit
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase small subunit family.
messages: Heterodimer of a large and a small subunit.

223919:F3K33 RS07150
gene id: 223919:F3K33_RS07150
uniprot id: A0A5P2EV46
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

223919:F3K33 RS01045
gene id: 223919:F3K33_RS01045
uniprot id: A0A5P2EQC1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

223919:F3K33 RS20655
gene id: 223919:F3K33_RS20655
uniprot id: A0A5P2ET81
names: Function
names: Similarity
messages: Belongs to the transposase 11 family.
messages: Involved in the transposition of the insertion sequence IS5.

223919:F3K33 RS10780
gene id: 223919:F3K33_RS10780
uniprot id: A0A5P2ETI4
names: Function
names: Subcellular Location Annotation
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.
messages: Membrane

223919:F3K33 RS00235
gene id: 223919:F3K33_RS00235
uniprot id: A0A5P2ERP4
names: Cofactor
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

223919:F3K33 RS23235
gene id: 223919:F3K33_RS23235
uniprot id: A0A5P2F2H1
names: Subcellular Location Annotation
messages: Membrane

223919:F3K33 RS14340
gene id: 223919:F3K33_RS14340
uniprot id: A0A5P2F696
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

223919:F3K33 RS03840
gene id: 223919:F3K33_RS03840
uniprot id: A0A5P2F0T5
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

223919:F3K33 RS19465
gene id: 223919:F3K33_RS19465
uniprot id: A0A5P2F196
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

223919:F3K33 RS12980
gene id: 223919:F3K33_RS12980
uniprot id: A0A5P2EUD6
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

223919:F3K33 RS08040
gene id: 223919:F3K33_RS08040
uniprot id: A0A5P2ERV9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

223919:F3K33 RS06330
gene id: 223919:F3K33_RS06330
uniprot id: A0A5P2ETD9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

223919:F3K33 RS05230
gene id: 223919:F3K33_RS05230
uniprot id: A0A5P2EU30
names: Cofactor
messages: Binds 1 zinc ion per subunit.

223919:F3K33 RS10105
gene id: 223919:F3K33_RS10105
uniprot id: A0A5P2ENT6
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

223919:F3K33 RS25340
gene id: 223919:F3K33_RS25340
uniprot id: A0A5P2F3S0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

223919:F3K33 RS13910
gene id: 223919:F3K33_RS13910
uniprot id: A0A5P2F615
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

223919:F3K33 RS00480
gene id: 223919:F3K33_RS00480
uniprot id: A0A5P2ENA8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

223919:F3K33 RS10840
gene id: 223919:F3K33_RS10840
uniprot id: A0A5P2ETI0
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

223919:F3K33 RS21845
gene id: 223919:F3K33_RS21845
uniprot id: A0A5P2EYW5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliF family.
messages: Membrane
messages: The M ring may be actively involved in energy transduction.

223919:F3K33 RS00845
gene id: 223919:F3K33_RS00845
uniprot id: A0A2P8RH15
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

223919:F3K33 RS20710
gene id: 223919:F3K33_RS20710
uniprot id: A0A5P2F9I9
names: Function
names: Similarity
messages: Belongs to the PduL family.
messages: Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate.

223919:F3K33 RS07050
gene id: 223919:F3K33_RS07050
uniprot id: A0A5P2EV99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

223919:F3K33 RS07530
gene id: 223919:F3K33_RS07530
uniprot id: A0A5P2EUE1
names: Similarity
messages: Belongs to the peptidase S8 family.

223919:F3K33 RS12985
gene id: 223919:F3K33_RS12985
uniprot id: A0A5P2EUJ6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
messages: Homodimer.

223919:F3K33 RS03155
gene id: 223919:F3K33_RS03155
uniprot id: A0A5P2ES35
names: Subcellular Location Annotation
messages: Membrane

223919:F3K33 RS06045
gene id: 223919:F3K33_RS06045
uniprot id: A0A5P2ETL0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

223919:F3K33 RS12035
gene id: 223919:F3K33_RS12035
uniprot id: A0A5P2EZV0
names: Similarity
messages: Belongs to the UPF0237 family.

223919:F3K33 RS12200
gene id: 223919:F3K33_RS12200
uniprot id: A0A5P2EU00
names: Function
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.
messages: Transcriptional repressor of xylose-utilizing enzymes.

223919:F3K33 RS00450
gene id: 223919:F3K33_RS00450
uniprot id: A0A5P2EZ47
names: Similarity
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.

223919:F3K33 RS10695
gene id: 223919:F3K33_RS10695
uniprot id: A0A5P2EWZ2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

223919:F3K33 RS15700
gene id: 223919:F3K33_RS15700
uniprot id: A0A5P2EVS9
names: Similarity
messages: Belongs to the UPF0751 family.

223919:F3K33 RS07130
gene id: 223919:F3K33_RS07130
uniprot id: A0A5P2ERR6
names: Similarity
messages: Belongs to the Fur family.

223919:F3K33 RS19480
gene id: 223919:F3K33_RS19480
uniprot id: A0A5P2F1Y2
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

223919:F3K33 RS00900
gene id: 223919:F3K33_RS00900
uniprot id: A0A5P2ERZ8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

223919:F3K33 RS22175
gene id: 223919:F3K33_RS22175
uniprot id: A0A5P2F1Y6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily.
messages: Homodimer.
messages: Involved in phosphonate degradation.

223919:F3K33 RS03315
gene id: 223919:F3K33_RS03315
uniprot id: A0A5P2EPL9
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

223919:F3K33 RS24165
gene id: 223919:F3K33_RS24165
uniprot id: A0A5P2FBC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

223919:F3K33 RS02675
gene id: 223919:F3K33_RS02675
uniprot id: A0A5P2ESU8
names: Similarity
messages: Belongs to the BMP lipoprotein family.

223919:F3K33 RS18275
gene id: 223919:F3K33_RS18275
uniprot id: A0A5P2EX07
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

223919:F3K33 RS08910
gene id: 223919:F3K33_RS08910
uniprot id: A0A5P2ESH8
names: Function
names: Similarity
messages: Belongs to the alpha/beta-type SASP family.
messages: SASP are bound to spore DNA. They are double-stranded DNA-binding proteins that cause DNA to change to an a-like conformation. They protect the DNA backbone from chemical and enzymatic cleavage and are thus involved in dormant spore's high resistance to UV light.

223919:F3K33 RS18950
gene id: 223919:F3K33_RS18950
uniprot id: A0A5P2F1P0
names: Subcellular Location Annotation
messages: Membrane

223919:F3K33 RS02155
gene id: 223919:F3K33_RS02155
uniprot id: A0A5P2EPE2
names: Subcellular Location Annotation
messages: Membrane

223919:F3K33 RS19770
gene id: 223919:F3K33_RS19770
uniprot id: A0A5P2F1N1
names: Subcellular Location Annotation
messages: Cytoplasm

223919:F3K33 RS17425
gene id: 223919:F3K33_RS17425
uniprot id: A0A5P2EX09
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

223919:F3K33 RS21240
gene id: 223919:F3K33_RS21240
uniprot id: A0A5P2F1G0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ClpS family.
messages: Binds to the N-terminal domain of the chaperone ClpA.
messages: Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.

223919:F3K33 RS14670
gene id: 223919:F3K33_RS14670
uniprot id: A0A5P2EVE7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

223919:F3K33 RS03430
gene id: 223919:F3K33_RS03430
uniprot id: A0A5P2EPY7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

223919:F3K33 RS12250
gene id: 223919:F3K33_RS12250
uniprot id: A0A5P2EU07
names: Similarity
messages: Belongs to the asparaginase 1 family.

223919:F3K33 RS24895
gene id: 223919:F3K33_RS24895
uniprot id: A0A5P2F2V8
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

223919:F3K33 RS23555
gene id: 223919:F3K33_RS23555
uniprot id: A0A5P2F2N0
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

223919:F3K33 RS01915
gene id: 223919:F3K33_RS01915
uniprot id: A0A5P2ERH5
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

223919:F3K33 RS23865
gene id: 223919:F3K33_RS23865
uniprot id: A0A5P2EZV2
names: Subcellular Location Annotation
messages: Membrane

223919:F3K33 RS07840
gene id: 223919:F3K33_RS07840
uniprot id: A0A5P2ES00
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

223919:F3K33 RS06290
gene id: 223919:F3K33_RS06290
uniprot id: A0A5P2EUW4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

223919:F3K33 RS01250
gene id: 223919:F3K33_RS01250
uniprot id: A0A5P2EP16
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

223919:F3K33 RS06440
gene id: 223919:F3K33_RS06440
uniprot id: A0A5P2EUZ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

223919:F3K33 RS22640
gene id: 223919:F3K33_RS22640
uniprot id: A0A5P2F1S9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. GalK subfamily.
messages: Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P).
messages: Cytoplasm

223919:F3K33 RS13050
gene id: 223919:F3K33_RS13050
uniprot id: A0A5P2EX85
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

223919:F3K33 RS06010
gene id: 223919:F3K33_RS06010
uniprot id: A0A5P2ER47
names: Function
names: Similarity
messages: Belongs to the transglycosylase MltG family.
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

223919:F3K33 RS02315
gene id: 223919:F3K33_RS02315
uniprot id: A0A5P2EQY9
names: Caution
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

223919:F3K33 RS01005
gene id: 223919:F3K33_RS01005
uniprot id: A0A5P2EZD9
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

223919:F3K33 RS05685
gene id: 223919:F3K33_RS05685
uniprot id: A0A5P2EQZ8
names: Similarity
messages: Belongs to the CpsD/CapB family.

223919:F3K33 RS21450
gene id: 223919:F3K33_RS21450
uniprot id: A0A5P2F1K7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the ABC transporter complex (TC 3.A.1.6.1) involved in sulfate/thiosulfate import.
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

223919:F3K33 RS04285
gene id: 223919:F3K33_RS04285
uniprot id: A0A5P2F112
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FNT transporter (TC 2.A.44) family.
messages: Membrane

223919:F3K33 RS24435
gene id: 223919:F3K33_RS24435
uniprot id: A0A5P2FBI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Cell membrane
messages: Membrane

223919:F3K33 RS20330
gene id: 223919:F3K33_RS20330
uniprot id: A0A5P2F1M9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

223919:F3K33 RS15895
gene id: 223919:F3K33_RS15895
uniprot id: A0A5P2EW73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0324 family.
messages: Membrane

223919:F3K33 RS09910
gene id: 223919:F3K33_RS09910
uniprot id: A0A5P2EVL3
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

223919:F3K33 RS22130
gene id: 223919:F3K33_RS22130
uniprot id: A0A5P2F5F6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M3B family.
messages: Binds 1 zinc ion.
messages: Has oligopeptidase activity and degrades a variety of small bioactive peptides.

223919:F3K33 RS12970
gene id: 223919:F3K33_RS12970
uniprot id: A0A5P2EX52
names: Cofactor
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.

223919:F3K33 RS01595
gene id: 223919:F3K33_RS01595
uniprot id: A0A5P2EU85
names: Similarity
messages: Belongs to the organic radical-activating enzymes family.

223919:F3K33 RS23130
gene id: 223919:F3K33_RS23130
uniprot id: A0A5P2FAU7
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

223919:F3K33 RS21765
gene id: 223919:F3K33_RS21765
uniprot id: A0A5P2FA54
names: Function
names: Similarity
messages: Belongs to the GTP-binding SRP family.
messages: Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum.

223919:F3K33 RS03595
gene id: 223919:F3K33_RS03595
uniprot id: A0A5P2ERM2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

223919:F3K33 RS24900
gene id: 223919:F3K33_RS24900
uniprot id: A0A5P2F440
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-C family. DnaE subfamily.
messages: Cytoplasm
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The alpha chain is the DNA polymerase.

223919:F3K33 RS06285
gene id: 223919:F3K33_RS06285
uniprot id: A0A5P2EUN2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

223919:F3K33 RS15260
gene id: 223919:F3K33_RS15260
uniprot id: A0A5P2EVV6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

223919:F3K33 RS09865
gene id: 223919:F3K33_RS09865
uniprot id: A0A5P2EYP0
names: Similarity
messages: Belongs to the RutC family.

223919:F3K33 RS04720
gene id: 223919:F3K33_RS04720
uniprot id: A0A5P2EQ95
names: Similarity
messages: Belongs to the type IA topoisomerase family.

223919:F3K33 RS17700
gene id: 223919:F3K33_RS17700
uniprot id: A0A5P2EZF3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

223919:F3K33 RS01660
gene id: 223919:F3K33_RS01660
uniprot id: A0A5P2EP24
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

223919:F3K33 RS02430
gene id: 223919:F3K33_RS02430
uniprot id: A0A5P2F029
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

223919:F3K33 RS06080
gene id: 223919:F3K33_RS06080
uniprot id: A0A5P2EUJ8
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

223919:F3K33 RS05605
gene id: 223919:F3K33_RS05605
uniprot id: A0A5P2EUI4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

223919:F3K33 RS18945
gene id: 223919:F3K33_RS18945
uniprot id: A0A5P2F104
names: Subcellular Location Annotation
messages: Membrane

223919:F3K33 RS20960
gene id: 223919:F3K33_RS20960
uniprot id: A0A5P2F0Z7
names: Subcellular Location Annotation
messages: Membrane

223919:F3K33 RS16915
gene id: 223919:F3K33_RS16915
uniprot id: A0A5P2EWH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0053 family.
messages: Membrane

223919:F3K33 RS09190
gene id: 223919:F3K33_RS09190
uniprot id: A0A5P2EYC7
names: Cofactor
names: Similarity
messages: Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.
messages: Binds 3 [4Fe-4S] clusters per subunit.

223919:F3K33 RS03445
gene id: 223919:F3K33_RS03445
uniprot id: A0A5P2ET45
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Membrane

223919:F3K33 RS09375
gene id: 223919:F3K33_RS09375
uniprot id: A0A5P2EW90
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

223919:F3K33 RS21585
gene id: 223919:F3K33_RS21585
uniprot id: A0A5P2F1B0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

223919:F3K33 RS02915
gene id: 223919:F3K33_RS02915
uniprot id: A0A5P2EPE8
names: Similarity
messages: Belongs to the pyruvate kinase family.

223919:F3K33 RS18215
gene id: 223919:F3K33_RS18215
uniprot id: A0A5P2EWZ8
names: Similarity
messages: Belongs to the thioesterase family.

223919:F3K33 RS26060
gene id: 223919:F3K33_RS26060
uniprot id: A0A5P2F4N7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

223919:F3K33 RS04650
gene id: 223919:F3K33_RS04650
uniprot id: A0A5P2F181
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

223919:F3K33 RS06865
gene id: 223919:F3K33_RS06865
uniprot id: A0A5P2ERJ0
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

223919:F3K33 RS01325
gene id: 223919:F3K33_RS01325
uniprot id: A0A5P2EZK0
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II CmtAB PTS system is involved in D-mannitol transport.

223919:F3K33 RS07305
gene id: 223919:F3K33_RS07305
uniprot id: A0A5P2ERR0
names: Similarity
messages: Belongs to the pyruvate kinase family.

223919:F3K33 RS08025
gene id: 223919:F3K33_RS08025
uniprot id: A0A5P2F2Y3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

223919:F3K33 RS11670
gene id: 223919:F3K33_RS11670
uniprot id: A0A5P2EXT9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

223919:F3K33 RS03765
gene id: 223919:F3K33_RS03765
uniprot id: A0A5P2ETA4
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

223919:F3K33 RS04480
gene id: 223919:F3K33_RS04480
uniprot id: A0A5P2ETN4
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

223919:F3K33 RS23370
gene id: 223919:F3K33_RS23370
uniprot id: A0A5P2F258
names: Subcellular Location Annotation
messages: Cytoplasm

223919:F3K33 RS08445
gene id: 223919:F3K33_RS08445
uniprot id: A0A5P2F364
names: Similarity
messages: Belongs to the TlyA family.

223919:F3K33 RS00230
gene id: 223919:F3K33_RS00230
uniprot id: A0A5P2ERK7
names: Similarity
messages: Belongs to the peptidase S8 family.

223919:F3K33 RS09560
gene id: 223919:F3K33_RS09560
uniprot id: A0A5P2F3S4
names: Similarity
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

223919:F3K33 RS03045
gene id: 223919:F3K33_RS03045
uniprot id: A0A5P2ET12
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

223919:F3K33 RS01470
gene id: 223919:F3K33_RS01470
uniprot id: A0A5P2ESA6
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

223919:F3K33 RS05875
gene id: 223919:F3K33_RS05875
uniprot id: A0A5P2F1V2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family.
messages: Membrane

223919:F3K33 RS08665
gene id: 223919:F3K33_RS08665
uniprot id: A0A5P2EY25
names: Similarity
messages: Belongs to the TrpC family.

223919:F3K33 RS04375
gene id: 223919:F3K33_RS04375
uniprot id: A0A5P2ETL3
names: Similarity
messages: Belongs to the peptidase M29 family.

223919:F3K33 RS02820
gene id: 223919:F3K33_RS02820
uniprot id: A0A5P2EPC6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

223919:F3K33 RS01675
gene id: 223919:F3K33_RS01675
uniprot id: A0A5P2EQN3
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

223919:F3K33 RS04515
gene id: 223919:F3K33_RS04515
uniprot id: A0A5P2EQE9
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

223919:F3K33 RS15210
gene id: 223919:F3K33_RS15210
uniprot id: A0A5P2EVU5
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

223919:F3K33 RS11235
gene id: 223919:F3K33_RS11235
uniprot id: A0A5P2EWB7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

223919:F3K33 RS05445
gene id: 223919:F3K33_RS05445
uniprot id: A0A5P2EU75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

223919:F3K33 RS22160
gene id: 223919:F3K33_RS22160
uniprot id: A0A5P2F2Q5
names: Similarity
messages: Belongs to the DltD family.

223919:F3K33 RS06320
gene id: 223919:F3K33_RS06320
uniprot id: A0A5P2ERA7
names: Function
names: Similarity
messages: Belongs to the UPF0122 family.
messages: Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein.

223919:F3K33 RS08240
gene id: 223919:F3K33_RS08240
uniprot id: A0A5P2EXU2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SepF family.
messages: Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
messages: Cytoplasm
messages: Homodimer. Interacts with FtsZ.

223919:F3K33 RS19670
gene id: 223919:F3K33_RS19670
uniprot id: A0A5P2EY62
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

223919:F3K33 RS13145
gene id: 223919:F3K33_RS13145
uniprot id: A0A5P2EUL6
names: Similarity
messages: Belongs to the peptidase S24 family.

223919:F3K33 RS23110
gene id: 223919:F3K33_RS23110
uniprot id: A0A5P2F212
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

223919:F3K33 RS13060
gene id: 223919:F3K33_RS13060
uniprot id: A0A5P2EYH3
names: Function
names: Similarity
messages: Belongs to the 'phage' integrase family.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.

223919:F3K33 RS18870
gene id: 223919:F3K33_RS18870
uniprot id: A0A5P2EXQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane

223919:F3K33 RS01315
gene id: 223919:F3K33_RS01315
uniprot id: A0A5P2ES44
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

223919:F3K33 RS09165
gene id: 223919:F3K33_RS09165
uniprot id: A0A5P2EUZ9
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

223919:F3K33 RS23265
gene id: 223919:F3K33_RS23265
uniprot id: A0A5P2F238
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

223919:F3K33 RS12320
gene id: 223919:F3K33_RS12320
uniprot id: A0A5P2EWV7
names: Similarity
messages: Belongs to the EamA transporter family.

223919:F3K33 RS05270
gene id: 223919:F3K33_RS05270
uniprot id: A0A5P2EQQ8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PyrK family.
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Heterotetramer of 2 PyrK and 2 PyrD type B subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(+).

223919:F3K33 RS24560
gene id: 223919:F3K33_RS24560
uniprot id: A0A5P2F0U0
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

223919:F3K33 RS17945
gene id: 223919:F3K33_RS17945
uniprot id: A0A5P2EX92
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

223919:F3K33 RS06610
gene id: 223919:F3K33_RS06610
uniprot id: A0A5P2ER69
names: Similarity
messages: Belongs to the glycosyl hydrolase 42 family.

223919:F3K33 RS17045
gene id: 223919:F3K33_RS17045
uniprot id: A0A5P2F0T7
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

223919:F3K33 RS12645
gene id: 223919:F3K33_RS12645
uniprot id: A0A5P2F079
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

223919:F3K33 RS05155
gene id: 223919:F3K33_RS05155
uniprot id: A0A5P2EQG0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

223919:F3K33 RS11420
gene id: 223919:F3K33_RS11420
uniprot id: A0A5P2EWF3
names: Subcellular Location Annotation
messages: Membrane

223919:F3K33 RS25425
gene id: 223919:F3K33_RS25425
uniprot id: A0A5P2F343
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

223919:F3K33 RS07820
gene id: 223919:F3K33_RS07820
uniprot id: A0A5P2F2V3
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

223919:F3K33 RS00710
gene id: 223919:F3K33_RS00710
uniprot id: A0A5P2ETR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

223919:F3K33 RS22125
gene id: 223919:F3K33_RS22125
uniprot id: A0A5P2F1X7
names: Subcellular Location Annotation
messages: Membrane

223919:F3K33 RS07085
gene id: 223919:F3K33_RS07085
uniprot id: A0A5P2ERM8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

223919:F3K33 RS11030
gene id: 223919:F3K33_RS11030
uniprot id: A0A5P2ETF5
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

223919:F3K33 RS22235
gene id: 223919:F3K33_RS22235
uniprot id: A0A5P2EYZ7
names: Similarity
messages: Belongs to the CdaR family.

223919:F3K33 RS15325
gene id: 223919:F3K33_RS15325
uniprot id: A0A5P2EVP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

223919:F3K33 RS06035
gene id: 223919:F3K33_RS06035
uniprot id: A0A5P2EUR6
names: Similarity
messages: Belongs to the GSP E family.

223919:F3K33 RS06890
gene id: 223919:F3K33_RS06890
uniprot id: A0A5P2EV71
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

223919:F3K33 RS06325
gene id: 223919:F3K33_RS06325
uniprot id: A0A5P2ER96
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

223919:F3K33 RS10860
gene id: 223919:F3K33_RS10860
uniprot id: A0A5P2F4I8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homotetramer.

223919:F3K33 RS06090
gene id: 223919:F3K33_RS06090
uniprot id: A0A5P2F1Z3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PstS family.
messages: Cell membrane
messages: Involved in the system for phosphate transport across the cytoplasmic membrane.
messages: Membrane
messages: Part of the ABC transporter complex PstSACB involved in phosphate import.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

223919:F3K33 RS24350
gene id: 223919:F3K33_RS24350
uniprot id: A0A5P2F0E3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

223919:F3K33 RS24925
gene id: 223919:F3K33_RS24925
uniprot id: A0A5P2F0D1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

223919:F3K33 RS03055
gene id: 223919:F3K33_RS03055
uniprot id: A0A5P2ES10
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

223919:F3K33 RS24965
gene id: 223919:F3K33_RS24965
uniprot id: A0A5P2F3J6
names: Similarity
messages: Belongs to the peptidase S41A family.

223919:F3K33 RS05990
gene id: 223919:F3K33_RS05990
uniprot id: A0A5P2ETK3
names: Similarity
messages: Belongs to the UPF0473 family.

223919:F3K33 RS00445
gene id: 223919:F3K33_RS00445
uniprot id: A0A5P2ERT0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

223919:F3K33 RS21750
gene id: 223919:F3K33_RS21750
uniprot id: A0A5P2F1D9
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

223919:F3K33 RS16365
gene id: 223919:F3K33_RS16365
uniprot id: A0A5P2EYY4
names: Function
names: Similarity
messages: Belongs to the 'phage' integrase family.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.

223919:F3K33 RS21140
gene id: 223919:F3K33_RS21140
uniprot id: A0A5P2F1E3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

223919:F3K33 RS01180
gene id: 223919:F3K33_RS01180
uniprot id: A0A5P2EU05
names: Similarity
messages: Belongs to the phosphate acetyltransferase and butyryltransferase family.

223919:F3K33 RS12010
gene id: 223919:F3K33_RS12010
uniprot id: A0A5P2EWP9
names: Function
names: Similarity
messages: Belongs to the alpha/beta-type SASP family.
messages: SASP are bound to spore DNA. They are double-stranded DNA-binding proteins that cause DNA to change to an a-like conformation. They protect the DNA backbone from chemical and enzymatic cleavage and are thus involved in dormant spore's high resistance to UV light.

223919:F3K33 RS00455
gene id: 223919:F3K33_RS00455
uniprot id: A0A5P2EQU4
names: Function
names: Similarity
messages: Belongs to the SpoVG family.
messages: Could be involved in septation.

223919:F3K33 RS08425
gene id: 223919:F3K33_RS08425
uniprot id: A0A5P2ES94
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

223919:F3K33 RS21280
gene id: 223919:F3K33_RS21280
uniprot id: A0A5P2F2Z8
names: Similarity
messages: Belongs to the heat shock protein 90 family.

223919:F3K33 RS06355
gene id: 223919:F3K33_RS06355
uniprot id: A0A5P2EWR8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.
messages: Cytoplasm
messages: Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity.

223919:F3K33 RS21630
gene id: 223919:F3K33_RS21630
uniprot id: A0A5P2EZ71
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

223919:F3K33 RS15865
gene id: 223919:F3K33_RS15865
uniprot id: A0A5P2F071
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PNP/UDP phosphorylase family.
messages: Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis.
messages: Cytoplasm

223919:F3K33 RS25505
gene id: 223919:F3K33_RS25505
uniprot id: A0A5P2F3V3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

223919:F3K33 RS03340
gene id: 223919:F3K33_RS03340
uniprot id: A0A5P2ERH6
names: Similarity
messages: Belongs to the Fur family.

223919:F3K33 RS08840
gene id: 223919:F3K33_RS08840
uniprot id: A0A5P2ESA0
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

223919:F3K33 RS06985
gene id: 223919:F3K33_RS06985
uniprot id: A0A5P2ETS3
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

223919:F3K33 RS12920
gene id: 223919:F3K33_RS12920
uniprot id: A0A5P2F0D6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

223919:F3K33 RS18485
gene id: 223919:F3K33_RS18485
uniprot id: A0A5P2EX10
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

223919:F3K33 RS03745
gene id: 223919:F3K33_RS03745
uniprot id: A0A5P2EPZ2
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

223919:F3K33 RS04125
gene id: 223919:F3K33_RS04125
uniprot id: A0A5P2EQ92
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

223919:F3K33 RS11380
gene id: 223919:F3K33_RS11380
uniprot id: A0A5P2ETL7
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

223919:F3K33 RS22940
gene id: 223919:F3K33_RS22940
uniprot id: A0A5P2EZI3
names: Similarity
messages: In the N-terminal section; belongs to the zinc metallo-hydrolase group 3 family.

223919:F3K33 RS04430
gene id: 223919:F3K33_RS04430
uniprot id: A0A5P2ETM4
names: Similarity
messages: Belongs to the peptidase S16 family.

223919:F3K33 RS14050
gene id: 223919:F3K33_RS14050
uniprot id: A0A5P2EXS3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. DbpA subfamily.
messages: Contains an N-terminal domain that binds non-specifically to RNA and a C-terminal domain that binds specifically and tightly to hairpin 92 of 23S rRNA.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes.

223919:F3K33 RS13120
gene id: 223919:F3K33_RS13120
uniprot id: A0A5P2EX83
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

223919:F3K33 RS12545
gene id: 223919:F3K33_RS12545
uniprot id: A0A5P2F054
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.
messages: Binds 3 [4Fe-4S] clusters.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

223919:F3K33 RS00795
gene id: 223919:F3K33_RS00795
uniprot id: A0A5P2ERX8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DisA family.
messages: Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation; upon encountering a lesion, the DisA focus arrests at the damaged site and halts c-di-AMP synthesis.
messages: Homooctamer.
messages: Participates in a DNA-damage check-point that is active prior to asymmetric division when DNA is damaged. DisA forms globular foci that rapidly scan along the chromosomes during sporulation, searching for lesions. When a lesion is present, DisA pauses at the lesion site. This triggers a cellular response that culminates in a temporary block in sporulation initiation.

223919:F3K33 RS07590
gene id: 223919:F3K33_RS07590
uniprot id: A0A5P2EXG9
names: Similarity
messages: Belongs to the 5'(3')-deoxyribonucleotidase family.

223919:F3K33 RS25445
gene id: 223919:F3K33_RS25445
uniprot id: A0A5P2FC12
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

223919:F3K33 RS01310
gene id: 223919:F3K33_RS01310
uniprot id: A0A5P2EQH4
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

223919:F3K33 RS14710
gene id: 223919:F3K33_RS14710
uniprot id: A0A5P2EV85
names: Subcellular Location Annotation
messages: Cytoplasm

223919:F3K33 RS15105
gene id: 223919:F3K33_RS15105
uniprot id: A0A5P2EVL0
names: Similarity
messages: Belongs to the UPF0251 family.

223919:F3K33 RS12705
gene id: 223919:F3K33_RS12705
uniprot id: A0A5P2EUE9
names: Similarity
names: Subunit
messages: Belongs to the RNase H family.
messages: Monomer.

223919:F3K33 RS09255
gene id: 223919:F3K33_RS09255
uniprot id: A0A5P2ESS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThrE exporter (TC 2.A.79) family.
messages: Membrane

223919:F3K33 RS17860
gene id: 223919:F3K33_RS17860
uniprot id: A0A5P2F0H5
names: Subcellular Location Annotation
messages: Membrane

223919:F3K33 RS02330
gene id: 223919:F3K33_RS02330
uniprot id: A0A5P2F011
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.

223919:F3K33 RS04635
gene id: 223919:F3K33_RS04635
uniprot id: A0A5P2ETR5
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

223919:F3K33 RS24635
gene id: 223919:F3K33_RS24635
uniprot id: A0A5P2F3Z4
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

223919:F3K33 RS18770
gene id: 223919:F3K33_RS18770
uniprot id: A0A5P2EX95
names: Subcellular Location Annotation
messages: Membrane

223919:F3K33 RS13350
gene id: 223919:F3K33_RS13350
uniprot id: A0A5P2EUQ9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

223919:F3K33 RS00915
gene id: 223919:F3K33_RS00915
uniprot id: A0A5P2ETV0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

223919:F3K33 RS22675
gene id: 223919:F3K33_RS22675
uniprot id: A0A5P2EZS2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial solute-binding protein 2 family.
messages: Periplasm
messages: The ABC transporter complex is composed of one ATP-binding protein (MglA), two transmembrane proteins (MglC) and a solute-binding protein (MglB).

223919:F3K33 RS03850
gene id: 223919:F3K33_RS03850
uniprot id: A0A5P2EVB9
names: Similarity
messages: Belongs to the barstar family.

223919:F3K33 RS07495
gene id: 223919:F3K33_RS07495
uniprot id: A0A5P2ERU7
names: Function
names: Similarity
messages: Belongs to the alpha/beta-type SASP family.
messages: SASP are bound to spore DNA. They are double-stranded DNA-binding proteins that cause DNA to change to an a-like conformation. They protect the DNA backbone from chemical and enzymatic cleavage and are thus involved in dormant spore's high resistance to UV light.

223919:F3K33 RS07475
gene id: 223919:F3K33_RS07475
uniprot id: A0A5P2F2Q1
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

223919:F3K33 RS15235
gene id: 223919:F3K33_RS15235
uniprot id: A0A5P2EZM3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

223919:F3K33 RS12040
gene id: 223919:F3K33_RS12040
uniprot id: A0A5P2ETX3
names: Similarity
names: Subunit
messages: Belongs to the UPF0210 family.
messages: Homodimer.

223919:F3K33 RS01135
gene id: 223919:F3K33_RS01135
uniprot id: A0A5P2ENZ7
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

223919:F3K33 RS05670
gene id: 223919:F3K33_RS05670
uniprot id: A0A5P2EWC7
names: Subcellular Location Annotation
messages: Membrane

223919:F3K33 RS14520
gene id: 223919:F3K33_RS14520
uniprot id: A0A5P2EZ95
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

223919:F3K33 RS07960
gene id: 223919:F3K33_RS07960
uniprot id: A0A5P2EUA8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvB family.
messages: Forms a complex with RuvA.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.

223919:F3K33 RS00210
gene id: 223919:F3K33_RS00210
uniprot id: A0A5P2ENF0
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

223919:F3K33 RS09750
gene id: 223919:F3K33_RS09750
uniprot id: A0A5P2F3V5
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

223919:F3K33 RS20220
gene id: 223919:F3K33_RS20220
uniprot id: A0A5P2F2A2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

223919:F3K33 RS24195
gene id: 223919:F3K33_RS24195
uniprot id: A0A5P2F1N6
names: Similarity
messages: Belongs to the CpsD/CapB family.

223919:F3K33 RS03175
gene id: 223919:F3K33_RS03175
uniprot id: A0A5P2EPU2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

223919:F3K33 RS19400
gene id: 223919:F3K33_RS19400
uniprot id: A0A5P2EXU0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhD family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for formate dehydrogenase (FDH) activity.

223919:F3K33 RS23675
gene id: 223919:F3K33_RS23675
uniprot id: A0A5P2F013
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

223919:F3K33 RS14790
gene id: 223919:F3K33_RS14790
uniprot id: A0A5P2EV96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

223919:F3K33 RS18715
gene id: 223919:F3K33_RS18715
uniprot id: A0A5P2EXF7
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

223919:F3K33 RS12860
gene id: 223919:F3K33_RS12860
uniprot id: A0A5P2EX33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

223919:F3K33 RS15335
gene id: 223919:F3K33_RS15335
uniprot id: A0A5P2EYD7
names: Similarity
messages: Belongs to the HypE family.

223919:F3K33 RS25525
gene id: 223919:F3K33_RS25525
uniprot id: A0A5P2F1D7
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

223919:F3K33 RS15505
gene id: 223919:F3K33_RS15505
uniprot id: A0A5P2EZS6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

223919:F3K33 RS06390
gene id: 223919:F3K33_RS06390
uniprot id: A0A5P2EUY3
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

223919:F3K33 RS00215
gene id: 223919:F3K33_RS00215
uniprot id: A0A5P2ENL1
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

223919:F3K33 RS23635
gene id: 223919:F3K33_RS23635
uniprot id: A0A5P2F2A7
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

223919:F3K33 RS06635
gene id: 223919:F3K33_RS06635
uniprot id: A0A5P2EUV2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LuxS family.
messages: Binds 1 Fe cation per subunit.
messages: Homodimer.
messages: Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).

223919:F3K33 RS13025
gene id: 223919:F3K33_RS13025
uniprot id: A0A5P2F0G0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

223919:F3K33 RS05045
gene id: 223919:F3K33_RS05045
uniprot id: A0A5P2EVZ2
names: Subcellular Location Annotation
messages: Cytoplasm

223919:F3K33 RS01140
gene id: 223919:F3K33_RS01140
uniprot id: A0A5P2ENK3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

223919:F3K33 RS23775
gene id: 223919:F3K33_RS23775
uniprot id: A0A5P2F034
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 4 family.
messages: Binds 1 NAD(+) per subunit.
messages: Homotetramer.

223919:F3K33 RS12535
gene id: 223919:F3K33_RS12535
uniprot id: A0A5P2F5C0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

223919:F3K33 RS13395
gene id: 223919:F3K33_RS13395
uniprot id: A0A5P2EUU1
names: Subcellular Location Annotation
messages: Membrane

223919:F3K33 RS01920
gene id: 223919:F3K33_RS01920
uniprot id: A0A5P2EUE0
names: Similarity
messages: Belongs to the nitroreductase family.

223919:F3K33 RS03750
gene id: 223919:F3K33_RS03750
uniprot id: A0A5P2EQ38
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

223919:F3K33 RS21980
gene id: 223919:F3K33_RS21980
uniprot id: A0A5P2EYU9
names: Similarity
messages: Belongs to the bacterial flagellin family.

223919:F3K33 RS02555
gene id: 223919:F3K33_RS02555
uniprot id: A0A5P2ESN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily.
messages: Cell membrane

223919:F3K33 RS09420
gene id: 223919:F3K33_RS09420
uniprot id: A0A5P2EVB6
names: Similarity
messages: Belongs to the transpeptidase family.

223919:F3K33 RS16645
gene id: 223919:F3K33_RS16645
uniprot id: A0A5P2EZY8
names: Similarity
messages: Belongs to the glycosyl hydrolase 25 family.

223919:F3K33 RS15350
gene id: 223919:F3K33_RS15350
uniprot id: A0A5P2F6R0
names: Similarity
messages: Belongs to the acylphosphatase family.
messages: Belongs to the carbamoyltransferase HypF family.

223919:F3K33 RS05310
gene id: 223919:F3K33_RS05310
uniprot id: A0A5P2EQQ5
names: Cofactor
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Binds 1 Fe(3+) ion per subunit.

223919:F3K33 RS19325
gene id: 223919:F3K33_RS19325
uniprot id: A0A5P2F0F9
names: Subcellular Location Annotation
messages: Membrane

223919:F3K33 RS12115
gene id: 223919:F3K33_RS12115
uniprot id: A0A5P2EXM3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose 5-phosphate isomerase family.
messages: Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
messages: Homodimer.

223919:F3K33 RS24160
gene id: 223919:F3K33_RS24160
uniprot id: A0A5P2F4I7
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

223919:F3K33 RS08895
gene id: 223919:F3K33_RS08895
uniprot id: A0A5P2ESA9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

223919:F3K33 RS13640
gene id: 223919:F3K33_RS13640
uniprot id: A0A5P2EYS4
names: Subcellular Location Annotation
messages: Membrane

223919:F3K33 RS17160
gene id: 223919:F3K33_RS17160
uniprot id: A0A5P2EZA5
names: Similarity
messages: Belongs to the PRORSD1 family.

223919:F3K33 RS22845
gene id: 223919:F3K33_RS22845
uniprot id: A0A5P2F1W6
names: Subcellular Location Annotation
messages: Membrane

223919:F3K33 RS26065
gene id: 223919:F3K33_RS26065
uniprot id: A0A5P2F5H9
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

223919:F3K33 RS24955
gene id: 223919:F3K33_RS24955
uniprot id: A0A5P2F4Y4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

223919:F3K33 RS01555
gene id: 223919:F3K33_RS01555
uniprot id: A0A5P2EP08
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

223919:F3K33 RS24940
gene id: 223919:F3K33_RS24940
uniprot id: A0A5P2F0L1
names: Subcellular Location Annotation
messages: Membrane

223919:F3K33 RS25050
gene id: 223919:F3K33_RS25050
uniprot id: A0A5P2F470
names: Similarity
messages: Belongs to the helicase family. RAD3/XPD subfamily.

223919:F3K33 RS24975
gene id: 223919:F3K33_RS24975
uniprot id: A0A5P2F0E0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division.

223919:F3K33 RS02145
gene id: 223919:F3K33_RS02145
uniprot id: A0A5P2EP09
names: Similarity
messages: Belongs to the peptidase U62 family.

223919:F3K33 RS09120
gene id: 223919:F3K33_RS09120
uniprot id: A0A5P2EW41
names: Similarity
messages: Belongs to the UxaA family.

223919:F3K33 RS18455
gene id: 223919:F3K33_RS18455
uniprot id: A0A5P2EZT0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

223919:F3K33 RS00140
gene id: 223919:F3K33_RS00140
uniprot id: A0A5P2EYY7
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type II sub-subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The autoendoproteolytic cleavage occurs by a canonical serine protease mechanism, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain. During this reaction, the Ser that is part of the protease active site of the proenzyme becomes the pyruvoyl prosthetic group, which constitutes an essential element of the active site of the mature decarboxylase.

223919:F3K33 RS13100
gene id: 223919:F3K33_RS13100
uniprot id: A0A5P2EX97
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

223919:F3K33 RS03105
gene id: 223919:F3K33_RS03105
uniprot id: A0A5P2ES26
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

223919:F3K33 RS00990
gene id: 223919:F3K33_RS00990
uniprot id: A0A5P2EQB0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

223919:F3K33 RS26115
gene id: 223919:F3K33_RS26115
uniprot id: A0A5P2F5I8
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

223919:F3K33 RS00250
gene id: 223919:F3K33_RS00250
uniprot id: A0A5P2ETJ0
names: Similarity
messages: Belongs to the ComB family.

223919:F3K33 RS12045
gene id: 223919:F3K33_RS12045
uniprot id: A0A5P2EU34
names: Cofactor
names: Similarity
messages: Belongs to the UPF0313 family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

223919:F3K33 RS00355
gene id: 223919:F3K33_RS00355
uniprot id: A0A5P2EQT0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

223919:F3K33 RS00030
gene id: 223919:F3K33_RS00030
uniprot id: A0A5P2ERI6
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

223919:F3K33 RS10650
gene id: 223919:F3K33_RS10650
uniprot id: A0A5P2EXA4
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

223919:F3K33 RS22755
gene id: 223919:F3K33_RS22755
uniprot id: A0A5P2F3S8
names: Similarity
messages: Belongs to the glycosyl hydrolase.

223919:F3K33 RS07025
gene id: 223919:F3K33_RS07025
uniprot id: A0A5P2ERL3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Lacks the C-terminal regulatory region which is replaced by HisZ.

223919:F3K33 RS04445
gene id: 223919:F3K33_RS04445
uniprot id: A0A5P2ESR2
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

223919:F3K33 RS03570
gene id: 223919:F3K33_RS03570
uniprot id: A0A5P2EV72
names: Similarity
messages: Belongs to the radical SAM superfamily. NifB family.

223919:F3K33 RS04605
gene id: 223919:F3K33_RS04605
uniprot id: A0A5P2EVR4
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

223919:F3K33 RS13525
gene id: 223919:F3K33_RS13525
uniprot id: A0A5P2F5V2
names: Similarity
messages: Belongs to the pirin family.

223919:F3K33 RS08055
gene id: 223919:F3K33_RS08055
uniprot id: A0A5P2ES32
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

223919:F3K33 RS06410
gene id: 223919:F3K33_RS06410
uniprot id: A0A5P2ER25
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

223919:F3K33 RS20770
gene id: 223919:F3K33_RS20770
uniprot id: A0A5P2F174
names: Subcellular Location Annotation
messages: Bacterial microcompartment

223919:F3K33 RS05180
gene id: 223919:F3K33_RS05180
uniprot id: A0A5P2EU20
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 26 family. TagA/TarA subfamily.
messages: Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid.

223919:F3K33 RS13750
gene id: 223919:F3K33_RS13750
uniprot id: A0A5P2EYU5
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

223919:F3K33 RS23700
gene id: 223919:F3K33_RS23700
uniprot id: A0A5P2FB50
names: Subcellular Location Annotation
messages: Cell membrane

223919:F3K33 RS02765
gene id: 223919:F3K33_RS02765
uniprot id: A0A5P2EPN1
names: Subcellular Location Annotation
messages: Membrane

223919:F3K33 RS02290
gene id: 223919:F3K33_RS02290
uniprot id: A0A5P2EUI6
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

223919:F3K33 RS10620
gene id: 223919:F3K33_RS10620
uniprot id: A0A5P2ET83
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

223919:F3K33 RS13975
gene id: 223919:F3K33_RS13975
uniprot id: A0A5P2EUX6
names: Subcellular Location Annotation
messages: Membrane

223919:F3K33 RS11335
gene id: 223919:F3K33_RS11335
uniprot id: A0A5P2ETQ6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

223919:F3K33 RS09505
gene id: 223919:F3K33_RS09505
uniprot id: A0A5P2F3R2
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A lyase-type mechanism (elimination/hydration) is suggested for the cleavage of the lactyl ether bond of MurNAc 6-phosphate, with the formation of an alpha,beta-unsaturated aldehyde intermediate with (E)-stereochemistry, followed by the syn addition of water to give product.
messages: Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.
messages: Homodimer.
messages: Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate.

223919:F3K33 RS01085
gene id: 223919:F3K33_RS01085
uniprot id: A0A5P2ENZ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the energy-coupling factor EcfT family.
messages: Cell membrane
messages: Forms a stable energy-coupling factor (ECF) transporter complex composed of 2 membrane-embedded substrate-binding proteins (S component), 2 ATP-binding proteins (A component) and 2 transmembrane proteins (T component).
messages: Membrane
messages: Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.

223919:F3K33 RS12365
gene id: 223919:F3K33_RS12365
uniprot id: A0A5P2EU70
names: Similarity
messages: Belongs to the GppA/Ppx family.

223919:F3K33 RS01010
gene id: 223919:F3K33_RS01010
uniprot id: A0A5P2ER28
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

223919:F3K33 RS21670
gene id: 223919:F3K33_RS21670
uniprot id: A0A5P2F566
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

223919:F3K33 RS07065
gene id: 223919:F3K33_RS07065
uniprot id: A0A5P2EX65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA-PH family.
messages: Cytoplasm

223919:F3K33 RS00290
gene id: 223919:F3K33_RS00290
uniprot id: A0A5P2ERL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily.
messages: Cell membrane

223919:F3K33 RS08670
gene id: 223919:F3K33_RS08670
uniprot id: A0A5P2ES68
names: Similarity
messages: Belongs to the TrpF family.

223919:F3K33 RS13005
gene id: 223919:F3K33_RS13005
uniprot id: A0A5P2EY28
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

223919:F3K33 RS25320
gene id: 223919:F3K33_RS25320
uniprot id: A0A5P2F321
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

223919:F3K33 RS12240
gene id: 223919:F3K33_RS12240
uniprot id: A0A5P2EWS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

223919:F3K33 RS02355
gene id: 223919:F3K33_RS02355
uniprot id: A0A5P2EPH5
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

223919:F3K33 RS13230
gene id: 223919:F3K33_RS13230
uniprot id: A0A5P2F0K5
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

223919:F3K33 RS00920
gene id: 223919:F3K33_RS00920
uniprot id: A0A5P2ENG1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

223919:F3K33 RS21525
gene id: 223919:F3K33_RS21525
uniprot id: A0A5P2EYQ4
names: Function
names: Similarity
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids threonine, isoleucine and methionine.

223919:F3K33 RS17020
gene id: 223919:F3K33_RS17020
uniprot id: A0A5P2EWT9
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase family.

223919:F3K33 RS11515
gene id: 223919:F3K33_RS11515
uniprot id: A0A5P2ETT5
names: Similarity
messages: Belongs to the HPA decarboxylase small subunit family.

223919:F3K33 RS14080
gene id: 223919:F3K33_RS14080
uniprot id: A0A5P2F131
names: Subcellular Location Annotation
messages: Cytoplasm

223919:F3K33 RS12170
gene id: 223919:F3K33_RS12170
uniprot id: A0A5P2EWS9
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

223919:F3K33 RS08875
gene id: 223919:F3K33_RS08875
uniprot id: A0A5P2EW83
names: Function
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family. DapH subfamily.
messages: Catalyzes the transfer of an acetyl group from acetyl-CoA to tetrahydrodipicolinate.

223919:F3K33 RS06810
gene id: 223919:F3K33_RS06810
uniprot id: A0A5P2ERA3
names: Function
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.

223919:F3K33 RS01100
gene id: 223919:F3K33_RS01100
uniprot id: A0A5P2ES06
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

223919:F3K33 RS06405
gene id: 223919:F3K33_RS06405
uniprot id: A0A5P2EWS8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

223919:F3K33 RS26095
gene id: 223919:F3K33_RS26095
uniprot id: A0A5P2F192
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

223919:F3K33 RS20570
gene id: 223919:F3K33_RS20570
uniprot id: A0A5P2EYE9
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

223919:F3K33 RS23025
gene id: 223919:F3K33_RS23025
uniprot id: A0A5P2F2D4
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

223919:F3K33 RS25455
gene id: 223919:F3K33_RS25455
uniprot id: A0A5P2F750
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

223919:F3K33 RS10430
gene id: 223919:F3K33_RS10430
uniprot id: A0A5P2EVX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

223919:F3K33 RS09295
gene id: 223919:F3K33_RS09295
uniprot id: A0A5P2F1G8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ScpA family.
messages: Component of a cohesin-like complex composed of ScpA, ScpB and the Smc homodimer, in which ScpA and ScpB bind to the head domain of Smc. The presence of the three proteins is required for the association of the complex with DNA.
messages: Cytoplasm
messages: Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves.

223919:F3K33 RS02860
gene id: 223919:F3K33_RS02860
uniprot id: A0A5P2EUT9
names: Function
names: Similarity
messages: Belongs to the alpha/beta-type SASP family.
messages: SASP are bound to spore DNA. They are double-stranded DNA-binding proteins that cause DNA to change to an a-like conformation. They protect the DNA backbone from chemical and enzymatic cleavage and are thus involved in dormant spore's high resistance to UV light.

223919:F3K33 RS21030
gene id: 223919:F3K33_RS21030
uniprot id: A0A5P2F1C5
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

223919:F3K33 RS16920
gene id: 223919:F3K33_RS16920
uniprot id: A0A5P2F5V9
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

223919:F3K33 RS09845
gene id: 223919:F3K33_RS09845
uniprot id: A0A5P2EWT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

223919:F3K33 RS13430
gene id: 223919:F3K33_RS13430
uniprot id: A0A5P2EXE1
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

223919:F3K33 RS23495
gene id: 223919:F3K33_RS23495
uniprot id: A0A5P2FB09
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

223919:F3K33 RS06630
gene id: 223919:F3K33_RS06630
uniprot id: A0A5P2ETK2
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

223919:F3K33 RS25335
gene id: 223919:F3K33_RS25335
uniprot id: A0A5P2FBZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

223919:F3K33 RS00995
gene id: 223919:F3K33_RS00995
uniprot id: A0A5P2ERY7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

223919:F3K33 RS16630
gene id: 223919:F3K33_RS16630
uniprot id: A0A5P2EWD9
names: Function
names: Similarity
messages: Belongs to the alpha/beta-type SASP family.
messages: SASP are bound to spore DNA. They are double-stranded DNA-binding proteins that cause DNA to change to an a-like conformation. They protect the DNA backbone from chemical and enzymatic cleavage and are thus involved in dormant spore's high resistance to UV light.

223919:F3K33 RS10320
gene id: 223919:F3K33_RS10320
uniprot id: A0A5P2ET81
names: Function
names: Similarity
messages: Belongs to the transposase 11 family.
messages: Involved in the transposition of the insertion sequence IS5.

223919:F3K33 RS05415
gene id: 223919:F3K33_RS05415
uniprot id: A0A5P2EQK5
names: Similarity
messages: Belongs to the GerABKA family.

223919:F3K33 RS01030
gene id: 223919:F3K33_RS01030
uniprot id: A0A5P2ENY5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

223919:F3K33 RS12915
gene id: 223919:F3K33_RS12915
uniprot id: A0A5P2EX43
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

223919:F3K33 RS04740
gene id: 223919:F3K33_RS04740
uniprot id: A0A5P2ESI6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

223919:F3K33 RS08965
gene id: 223919:F3K33_RS08965
uniprot id: A0A5P2EUV3
names: Subcellular Location Annotation
messages: Membrane

223919:F3K33 RS03970
gene id: 223919:F3K33_RS03970
uniprot id: A0A5P2EPY6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

223919:F3K33 RS15080
gene id: 223919:F3K33_RS15080
uniprot id: A0A5P2EY90
names: Subcellular Location Annotation
messages: Membrane

223919:F3K33 RS17430
gene id: 223919:F3K33_RS17430
uniprot id: A0A5P2EWS5
names: Similarity
messages: Belongs to the EamA transporter family.

223919:F3K33 RS21190
gene id: 223919:F3K33_RS21190
uniprot id: A0A5P2F1F2
names: Subcellular Location Annotation
messages: Membrane

223919:F3K33 RS12530
gene id: 223919:F3K33_RS12530
uniprot id: A0A5P2EY83
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RnfG family.
messages: Cell membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

223919:F3K33 RS21185
gene id: 223919:F3K33_RS21185
uniprot id: A0A5P2F9T6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

223919:F3K33 RS08415
gene id: 223919:F3K33_RS08415
uniprot id: A0A5P2ES93
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

223919:F3K33 RS13540
gene id: 223919:F3K33_RS13540
uniprot id: A0A5P2EUP3
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

223919:F3K33 RS14440
gene id: 223919:F3K33_RS14440
uniprot id: A0A5P2EVG3
names: Similarity
messages: Belongs to the DODA-type extradiol aromatic ring-opening dioxygenase family.

223919:F3K33 RS15855
gene id: 223919:F3K33_RS15855
uniprot id: A0A5P2EYM6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphopentomutase family.
messages: Binds 1 or 2 manganese ions.
messages: Cytoplasm
messages: Phosphotransfer between the C1 and C5 carbon atoms of pentose.

223919:F3K33 RS23230
gene id: 223919:F3K33_RS23230
uniprot id: A0A5P2FAW8
names: Subcellular Location Annotation
messages: Membrane

223919:F3K33 RS13165
gene id: 223919:F3K33_RS13165
uniprot id: A0A5P2EYJ3
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

223919:F3K33 RS22595
gene id: 223919:F3K33_RS22595
uniprot id: A0A5P2F2W6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the spermidine/spermine synthase family.
messages: Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
messages: Homodimer or homotetramer.

223919:F3K33 RS09545
gene id: 223919:F3K33_RS09545
uniprot id: A0A5P2EVD9
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

223919:F3K33 RS12805
gene id: 223919:F3K33_RS12805
uniprot id: A0A5P2F5G6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial solute-binding protein 2 family.
messages: Periplasm
messages: The ABC transporter complex is composed of one ATP-binding protein (MglA), two transmembrane proteins (MglC) and a solute-binding protein (MglB).

223919:F3K33 RS08410
gene id: 223919:F3K33_RS08410
uniprot id: A0A5P2ES25
names: Similarity
messages: Belongs to the asp23 family.

223919:F3K33 RS09975
gene id: 223919:F3K33_RS09975
uniprot id: A0A5P2ESW6
names: Similarity
messages: Belongs to the P(II) protein family.

223919:F3K33 RS01040
gene id: 223919:F3K33_RS01040
uniprot id: A0A5P2ENI1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

223919:F3K33 RS04595
gene id: 223919:F3K33_RS04595
uniprot id: A0A5P2F173
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Membrane

223919:F3K33 RS03415
gene id: 223919:F3K33_RS03415
uniprot id: A0A5P2EV47
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

223919:F3K33 RS22765
gene id: 223919:F3K33_RS22765
uniprot id: A0A5P2F289
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

223919:F3K33 RS14665
gene id: 223919:F3K33_RS14665
uniprot id: A0A5P2EVK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

223919:F3K33 RS07695
gene id: 223919:F3K33_RS07695
uniprot id: A0A5P2EVD3
names: Subcellular Location Annotation
messages: Membrane

223919:F3K33 RS25795
gene id: 223919:F3K33_RS25795
uniprot id: A0A5P2F1J1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

223919:F3K33 RS04550
gene id: 223919:F3K33_RS04550
uniprot id: A0A5P2EST0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

223919:F3K33 RS25680
gene id: 223919:F3K33_RS25680
uniprot id: A0A5P2F1G9
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 4 family.
messages: Binds 1 NAD(+) per subunit.
messages: Homotetramer.

223919:F3K33 RS02785
gene id: 223919:F3K33_RS02785
uniprot id: A0A5P2ESW7
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

223919:F3K33 RS06400
gene id: 223919:F3K33_RS06400
uniprot id: A0A5P2ETS9
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by GTP. Inhibited by UTP.
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

223919:F3K33 RS21805
gene id: 223919:F3K33_RS21805
uniprot id: A0A5P2F2J0
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

223919:F3K33 RS07285
gene id: 223919:F3K33_RS07285
uniprot id: A0A5P2EXA6
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HPrK/P family.
messages: Both phosphorylation and phosphorolysis are carried out by the same active site and suggest a common mechanism for both reactions.
messages: Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr). The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK/P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport: it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion.
messages: Homohexamer.
messages: The Walker A ATP-binding motif also binds Pi and PPi.

223919:F3K33 RS09605
gene id: 223919:F3K33_RS09605
uniprot id: A0A5P2EWP2
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

223919:F3K33 RS04410
gene id: 223919:F3K33_RS04410
uniprot id: A0A5P2EQA4
names: Subcellular Location Annotation
messages: Membrane

223919:F3K33 RS11480
gene id: 223919:F3K33_RS11480
uniprot id: A0A5P2EWG0
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

223919:F3K33 RS01540
gene id: 223919:F3K33_RS01540
uniprot id: A0A5P2ERC6
names: Similarity
messages: In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
messages: In the N-terminal section; belongs to the aldehyde dehydrogenase family.

223919:F3K33 RS19795
gene id: 223919:F3K33_RS19795
uniprot id: A0A5P2F1K6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

223919:F3K33 RS08200
gene id: 223919:F3K33_RS08200
uniprot id: A0A5P2ES60
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

223919:F3K33 RS08225
gene id: 223919:F3K33_RS08225
uniprot id: A0A5P2EVV4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sbp family.
messages: Cell membrane

223919:F3K33 RS01125
gene id: 223919:F3K33_RS01125
uniprot id: A0A5P2ENJ9
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

223919:F3K33 RS20785
gene id: 223919:F3K33_RS20785
uniprot id: A0A5P2EYR2
names: Similarity
messages: Belongs to the peptidase C56 family.

223919:F3K33 RS20225
gene id: 223919:F3K33_RS20225
uniprot id: A0A5P2F9A3
names: Similarity
messages: Belongs to the peptidase S8 family.

223919:F3K33 RS04735
gene id: 223919:F3K33_RS04735
uniprot id: A0A5P2EQF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

223919:F3K33 RS07440
gene id: 223919:F3K33_RS07440
uniprot id: A0A5P2ERK6
names: Similarity
messages: Belongs to the peptidase S8 family.

223919:F3K33 RS23140
gene id: 223919:F3K33_RS23140
uniprot id: A0A5P2F5Y3
names: Subcellular Location Annotation
messages: Membrane

223919:F3K33 RS07965
gene id: 223919:F3K33_RS07965
uniprot id: A0A5P2EVH9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

223919:F3K33 RS07970
gene id: 223919:F3K33_RS07970
uniprot id: A0A5P2EVQ7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

223919:F3K33 RS09480
gene id: 223919:F3K33_RS09480
uniprot id: A0A5P2EVC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

223919:F3K33 RS23095
gene id: 223919:F3K33_RS23095
uniprot id: A0A5P2EZQ9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

223919:F3K33 RS23805
gene id: 223919:F3K33_RS23805
uniprot id: A0A5P2F2W9
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

223919:F3K33 RS00865
gene id: 223919:F3K33_RS00865
uniprot id: A0A5P2ETU0
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

223919:F3K33 RS20110
gene id: 223919:F3K33_RS20110
uniprot id: A0A5P2F1J7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial solute-binding protein 2 family.
messages: Periplasm
messages: The ABC transporter complex is composed of one ATP-binding protein (MglA), two transmembrane proteins (MglC) and a solute-binding protein (MglB).

223919:F3K33 RS04070
gene id: 223919:F3K33_RS04070
uniprot id: A0A5P2EQ83
names: Similarity
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.

223919:F3K33 RS10180
gene id: 223919:F3K33_RS10180
uniprot id: A0A5P2F448
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

223919:F3K33 RS10610
gene id: 223919:F3K33_RS10610
uniprot id: A0A5P2EW01
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 2 subfamily.
messages: Cytoplasm
messages: Homodimer.

223919:F3K33 RS10615
gene id: 223919:F3K33_RS10615
uniprot id: A0A5P2EZ30
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

223919:F3K33 RS04180
gene id: 223919:F3K33_RS04180
uniprot id: A0A5P2EVI0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

223919:F3K33 RS23560
gene id: 223919:F3K33_RS23560
uniprot id: A0A5P2F657
names: Subcellular Location Annotation
messages: Membrane

223919:F3K33 RS24375
gene id: 223919:F3K33_RS24375
uniprot id: A0A5P2F4M8
names: Similarity
messages: Belongs to the peptidase M18 family.

223919:F3K33 RS17270
gene id: 223919:F3K33_RS17270
uniprot id: A0A5P2EZC4
names: Function
names: Similarity
messages: Belongs to the KptA/TPT1 family.
messages: Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP-ribose 1''-2''-cyclic phosphate (APPR>P). May function as an ADP-ribosylase.

223919:F3K33 RS15665
gene id: 223919:F3K33_RS15665
uniprot id: A0A5P2F6W8
names: Function
names: Similarity
messages: Belongs to the alpha/beta-type SASP family.
messages: SASP are bound to spore DNA. They are double-stranded DNA-binding proteins that cause DNA to change to an a-like conformation. They protect the DNA backbone from chemical and enzymatic cleavage and are thus involved in dormant spore's high resistance to UV light.

223919:F3K33 RS08930
gene id: 223919:F3K33_RS08930
uniprot id: A0A5P2F3F4
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

223919:F3K33 RS11640
gene id: 223919:F3K33_RS11640
uniprot id: A0A5P2ETX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

223919:F3K33 RS23365
gene id: 223919:F3K33_RS23365
uniprot id: A0A5P2EZR3
names: Subcellular Location Annotation
messages: Membrane

223919:F3K33 RS10120
gene id: 223919:F3K33_RS10120
uniprot id: A0A5P2ESD5
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

223919:F3K33 RS14735
gene id: 223919:F3K33_RS14735
uniprot id: A0A5P2EYX9
names: Subcellular Location Annotation
messages: Membrane

223919:F3K33 RS09965
gene id: 223919:F3K33_RS09965
uniprot id: A0A5P2EVM1
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the NifH/BchL/ChlL family.
messages: Binds 1 [4Fe-4S] cluster per dimer.
messages: Homodimer.
messages: The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein.
messages: The reversible ADP-ribosylation of Arg inactivates the nitrogenase reductase and regulates nitrogenase activity.
messages: The reversible ADP-ribosylation of Arg-97 inactivates the nitrogenase reductase and regulates nitrogenase activity.

223919:F3K33 RS25265
gene id: 223919:F3K33_RS25265
uniprot id: A0A5P2F0R4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

223919:F3K33 RS05185
gene id: 223919:F3K33_RS05185
uniprot id: A0A5P2EU86
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Membrane

223919:F3K33 RS00395
gene id: 223919:F3K33_RS00395
uniprot id: A0A5P2ERR8
names: Function
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.
messages: This protein is a Fe-Mo-cofactor biosynthetic component.

223919:F3K33 RS24525
gene id: 223919:F3K33_RS24525
uniprot id: A0A5P2F2Q8
names: Subcellular Location Annotation
messages: Membrane

223919:F3K33 RS11630
gene id: 223919:F3K33_RS11630
uniprot id: A0A5P2ETQ4
names: Subcellular Location Annotation
messages: Membrane

223919:F3K33 RS24345
gene id: 223919:F3K33_RS24345
uniprot id: A0A5P2F0P7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

223919:F3K33 RS22275
gene id: 223919:F3K33_RS22275
uniprot id: A0A5P2F206
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

223919:F3K33 RS20810
gene id: 223919:F3K33_RS20810
uniprot id: A0A5P2F241
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

223919:F3K33 RS07855
gene id: 223919:F3K33_RS07855
uniprot id: A0A5P2EU89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

223919:F3K33 RS24910
gene id: 223919:F3K33_RS24910
uniprot id: A0A5P2FBS3
names: Function
names: Similarity
messages: Belongs to the WhiA family.
messages: Involved in cell division and chromosome segregation.

223919:F3K33 RS08885
gene id: 223919:F3K33_RS08885
uniprot id: A0A5P2EV37
names: Function
names: Similarity
messages: Belongs to the nucleoside phosphorylase PpnP family.
messages: Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions.

223919:F3K33 RS16085
gene id: 223919:F3K33_RS16085
uniprot id: A0A5P2F753
names: Subcellular Location Annotation
messages: Cell membrane

223919:F3K33 RS04080
gene id: 223919:F3K33_RS04080
uniprot id: A0A5P2EQ05
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

223919:F3K33 RS09530
gene id: 223919:F3K33_RS09530
uniprot id: A0A5P2ESX0
names: Similarity
messages: Belongs to the agmatine deiminase family.

223919:F3K33 RS02500
gene id: 223919:F3K33_RS02500
uniprot id: A0A5P2ER22
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

223919:F3K33 RS23070
gene id: 223919:F3K33_RS23070
uniprot id: A0A5P2FAT7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

223919:F3K33 RS21590
gene id: 223919:F3K33_RS21590
uniprot id: A0A5P2F2D7
names: Similarity
messages: Belongs to the GSP E family.

223919:F3K33 RS20395
gene id: 223919:F3K33_RS20395
uniprot id: A0A5P2F105
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0053 family.
messages: Membrane

223919:F3K33 RS18095
gene id: 223919:F3K33_RS18095
uniprot id: A0A5P2EXB8
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

223919:F3K33 RS00500
gene id: 223919:F3K33_RS00500
uniprot id: A0A5P2EZ57
names: Subcellular Location Annotation
messages: Membrane

223919:F3K33 RS10625
gene id: 223919:F3K33_RS10625
uniprot id: A0A5P2ETE8
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

223919:F3K33 RS15040
gene id: 223919:F3K33_RS15040
uniprot id: A0A5P2EVC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

223919:F3K33 RS18885
gene id: 223919:F3K33_RS18885
uniprot id: A0A5P2F000
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. HypB/HupM subfamily.

223919:F3K33 RS21220
gene id: 223919:F3K33_RS21220
uniprot id: A0A5P2F144
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

223919:F3K33 RS23345
gene id: 223919:F3K33_RS23345
uniprot id: A0A5P2EZL1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

223919:F3K33 RS23565
gene id: 223919:F3K33_RS23565
uniprot id: A0A5P2EZP7
names: Similarity
messages: Belongs to the polysaccharide synthase family.

223919:F3K33 RS14085
gene id: 223919:F3K33_RS14085
uniprot id: A0A5P2EUZ4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LDH/MDH superfamily. LDH family.
messages: Catalyzes the conversion of lactate to pyruvate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

223919:F3K33 RS15780
gene id: 223919:F3K33_RS15780
uniprot id: A0A5P2F246
names: Function
names: Similarity
messages: Belongs to the alpha/beta-type SASP family.
messages: SASP are bound to spore DNA. They are double-stranded DNA-binding proteins that cause DNA to change to an a-like conformation. They protect the DNA backbone from chemical and enzymatic cleavage and are thus involved in dormant spore's high resistance to UV light.

223919:F3K33 RS09015
gene id: 223919:F3K33_RS09015
uniprot id: A0A5P2EUW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

223919:F3K33 RS00620
gene id: 223919:F3K33_RS00620
uniprot id: A0A5P2ENK8
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

223919:F3K33 RS17605
gene id: 223919:F3K33_RS17605
uniprot id: A0A5P2EZH5
names: Subcellular Location Annotation
messages: Membrane

223919:F3K33 RS24625
gene id: 223919:F3K33_RS24625
uniprot id: A0A5P2F0E4
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

223919:F3K33 RS18605
gene id: 223919:F3K33_RS18605
uniprot id: A0A5P2EX64
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

223919:F3K33 RS12275
gene id: 223919:F3K33_RS12275
uniprot id: A0A5P2EXQ2
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

223919:F3K33 RS21245
gene id: 223919:F3K33_RS21245
uniprot id: A0A5P2F4X7
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-I family.

223919:F3K33 RS20920
gene id: 223919:F3K33_RS20920
uniprot id: A0A5P2F2P2
names: Subcellular Location Annotation
messages: Membrane

223919:F3K33 RS24475
gene id: 223919:F3K33_RS24475
uniprot id: A0A5P2F3W8
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.

223919:F3K33 RS23050
gene id: 223919:F3K33_RS23050
uniprot id: A0A5P2EZK2
names: Activity Regulation
names: Function
names: Similarity
names: Subunit
messages: Activated by phosphorylation and inhibited by fructose 1,6-bisphosphate (FBP).
messages: Belongs to the FGGY kinase family.
messages: Homotetramer and homodimer (in equilibrium).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.

223919:F3K33 RS06835
gene id: 223919:F3K33_RS06835
uniprot id: A0A5P2EUZ0
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.

223919:F3K33 RS25840
gene id: 223919:F3K33_RS25840
uniprot id: A0A5P2F3B0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glutaminase PdxT/SNO family.
messages: Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.
messages: In the presence of PdxS, forms a dodecamer of heterodimers. Only shows activity in the heterodimer.

223919:F3K33 RS07955
gene id: 223919:F3K33_RS07955
uniprot id: A0A5P2ES17
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

223919:F3K33 RS03935
gene id: 223919:F3K33_RS03935
uniprot id: A0A5P2ETH6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

223919:F3K33 RS04500
gene id: 223919:F3K33_RS04500
uniprot id: A0A5P2EVP2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

223919:F3K33 RS25910
gene id: 223919:F3K33_RS25910
uniprot id: A0A5P2F429
names: Similarity
messages: In the N-terminal section; belongs to the zinc metallo-hydrolase group 3 family.

223919:F3K33 RS25030
gene id: 223919:F3K33_RS25030
uniprot id: A0A5P2F138
names: Subcellular Location Annotation
messages: Membrane

223919:F3K33 RS07430
gene id: 223919:F3K33_RS07430
uniprot id: A0A5P2EUC0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HCP family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Binds 1 hybrid [4Fe-2O-2S] cluster.
messages: Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
messages: Cytoplasm

223919:F3K33 RS07170
gene id: 223919:F3K33_RS07170
uniprot id: A0A5P2EX87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

223919:F3K33 RS02985
gene id: 223919:F3K33_RS02985
uniprot id: A0A5P2ERB1
names: Subcellular Location Annotation
messages: Membrane

223919:F3K33 RS22585
gene id: 223919:F3K33_RS22585
uniprot id: A0A5P2EZB0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. NspC subfamily.
messages: Cytoplasm
messages: Homodimer.

223919:F3K33 RS25245
gene id: 223919:F3K33_RS25245
uniprot id: A0A5P2FCV3
names: Subcellular Location Annotation
messages: Cytoplasm

223919:F3K33 RS09205
gene id: 223919:F3K33_RS09205
uniprot id: A0A5P2ESR6
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

223919:F3K33 RS24980
gene id: 223919:F3K33_RS24980
uniprot id: A0A5P2F128
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

223919:F3K33 RS25180
gene id: 223919:F3K33_RS25180
uniprot id: A0A5P2F0Q2
names: Function
names: Similarity
messages: Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PDRP subfamily.
messages: Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation.

223919:F3K33 RS13080
gene id: 223919:F3K33_RS13080
uniprot id: A0A5P2EUF5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

223919:F3K33 RS02975
gene id: 223919:F3K33_RS02975
uniprot id: A0A5P2EPQ9
names: Function
names: Similarity
messages: ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.
messages: Belongs to the ParA family. MinD subfamily.

223919:F3K33 RS01000
gene id: 223919:F3K33_RS01000
uniprot id: A0A5P2ES21
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

223919:F3K33 RS21385
gene id: 223919:F3K33_RS21385
uniprot id: A0A5P2F9X8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

223919:F3K33 RS01195
gene id: 223919:F3K33_RS01195
uniprot id: A0A5P2EP07
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

223919:F3K33 RS24610
gene id: 223919:F3K33_RS24610
uniprot id: A0A5P2F072
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

223919:F3K33 RS22085
gene id: 223919:F3K33_RS22085
uniprot id: A0A5P2EYW6
names: Cofactor
names: Similarity
messages: Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.
messages: Binds 3 [4Fe-4S] clusters per subunit.

223919:F3K33 RS15810
gene id: 223919:F3K33_RS15810
uniprot id: A0A5P2EZH9
names: Subcellular Location Annotation
messages: Membrane

223919:F3K33 RS14545
gene id: 223919:F3K33_RS14545
uniprot id: A0A5P2EV66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

223919:F3K33 RS02195
gene id: 223919:F3K33_RS02195
uniprot id: A0A5P2EP17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1C family.
messages: Membrane

223919:F3K33 RS05505
gene id: 223919:F3K33_RS05505
uniprot id: A0A5P2F1P5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

223919:F3K33 RS01680
gene id: 223919:F3K33_RS01680
uniprot id: A0A5P2ESA5
names: Function
names: Similarity
messages: Belongs to the 'phage' integrase family.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.

223919:F3K33 RS19935
gene id: 223919:F3K33_RS19935
uniprot id: A0A5P2F1G7
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

223919:F3K33 RS09170
gene id: 223919:F3K33_RS09170
uniprot id: A0A5P2EW47
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

223919:F3K33 RS13015
gene id: 223919:F3K33_RS13015
uniprot id: A0A5P2F5K7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Membrane

223919:F3K33 RS08290
gene id: 223919:F3K33_RS08290
uniprot id: A0A5P2EXV3
names: Function
names: Similarity
names: Subunit
messages: Associates with stalled 50S ribosomal subunits.
messages: Belongs to the NEMF family.
messages: Part of the ribosome quality control system (RQC). Recruits Ala-charged tRNA and directs the elongation of stalled nascent chains on 50S ribosomal subunits, leading to non-templated C-terminal Ala extensions (Ala tail). The Ala tail promotes nascent chain degradation. May add between 1 and at least 8 Ala residues. Binds to stalled 50S ribosomal subunits.

223919:F3K33 RS22975
gene id: 223919:F3K33_RS22975
uniprot id: A0A5P2EZD7
names: Function
names: Similarity
messages: Belongs to the Thz kinase family.
messages: Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).

223919:F3K33 RS20890
gene id: 223919:F3K33_RS20890
uniprot id: A0A5P2EY91
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Uronate isomerase family.

223919:F3K33 RS06435
gene id: 223919:F3K33_RS06435
uniprot id: A0A5P2EUR4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

223919:F3K33 RS08455
gene id: 223919:F3K33_RS08455
uniprot id: A0A5P2EXY2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

223919:F3K33 RS04105
gene id: 223919:F3K33_RS04105
uniprot id: A0A5P2ESK1
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

223919:F3K33 RS00805
gene id: 223919:F3K33_RS00805
uniprot id: A0A5P2EQZ1
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

223919:F3K33 RS06780
gene id: 223919:F3K33_RS06780
uniprot id: A0A5P2ETN3
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

223919:F3K33 RS02670
gene id: 223919:F3K33_RS02670
uniprot id: A0A5P2ESQ6
names: Subcellular Location Annotation
messages: Membrane

223919:F3K33 RS09405
gene id: 223919:F3K33_RS09405
uniprot id: A0A5P2EST3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

223919:F3K33 RS23340
gene id: 223919:F3K33_RS23340
uniprot id: A0A5P2F621
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase D family. Cardiolipin synthase subfamily.
messages: Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

223919:F3K33 RS23080
gene id: 223919:F3K33_RS23080
uniprot id: A0A5P2F5X7
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

223919:F3K33 RS22705
gene id: 223919:F3K33_RS22705
uniprot id: A0A5P2F1N3
names: Subcellular Location Annotation
messages: Membrane

223919:F3K33 RS02380
gene id: 223919:F3K33_RS02380
uniprot id: A0A5P2F019
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

223919:F3K33 RS22230
gene id: 223919:F3K33_RS22230
uniprot id: A0A5P2F5H8
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

223919:F3K33 RS26185
gene id: 223919:F3K33_RS26185
uniprot id: A0A5P2F473
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

223919:F3K33 RS00190
gene id: 223919:F3K33_RS00190
uniprot id: A0A5P2EZ00
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

223919:F3K33 RS19515
gene id: 223919:F3K33_RS19515
uniprot id: A0A5P2EXV9
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase family.

223919:F3K33 RS08165
gene id: 223919:F3K33_RS08165
uniprot id: A0A5P2EVM6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

223919:F3K33 RS08190
gene id: 223919:F3K33_RS08190
uniprot id: A0A5P2EXT2
names: Similarity
messages: Belongs to the transpeptidase family.

223919:F3K33 RS04700
gene id: 223919:F3K33_RS04700
uniprot id: A0A5P2ETY8
names: Similarity
messages: Belongs to the disproportionating enzyme family.

223919:F3K33 RS08230
gene id: 223919:F3K33_RS08230
uniprot id: A0A5P2F324
names: Similarity
messages: Belongs to the UPF0749 family.

223919:F3K33 RS23800
gene id: 223919:F3K33_RS23800
uniprot id: A0A5P2FB64
names: Similarity
messages: Belongs to the glycosyl hydrolase 30 family.

223919:F3K33 RS05275
gene id: 223919:F3K33_RS05275
uniprot id: A0A5P2ESU3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate.
messages: Cytoplasm

223919:F3K33 RS20335
gene id: 223919:F3K33_RS20335
uniprot id: A0A5P2F2C3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

223919:F3K33 RS03190
gene id: 223919:F3K33_RS03190
uniprot id: A0A5P2ESZ9
names: Similarity
messages: Belongs to the phosphohexose mutase family.

223919:F3K33 RS24595
gene id: 223919:F3K33_RS24595
uniprot id: A0A5P2FBL3
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

223919:F3K33 RS11880
gene id: 223919:F3K33_RS11880
uniprot id: A0A5P2EWK9
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

223919:F3K33 RS02110
gene id: 223919:F3K33_RS02110
uniprot id: A0A5P2ERI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0719 family.
messages: Membrane

223919:F3K33 RS19550
gene id: 223919:F3K33_RS19550
uniprot id: A0A5P2F0K3
names: Subcellular Location Annotation
messages: Membrane

223919:F3K33 RS13775
gene id: 223919:F3K33_RS13775
uniprot id: A0A5P2EUY7
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

223919:F3K33 RS12190
gene id: 223919:F3K33_RS12190
uniprot id: A0A5P2EWR7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the xylose isomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.

223919:F3K33 RS07055
gene id: 223919:F3K33_RS07055
uniprot id: A0A5P2F2H2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

223919:F3K33 RS06480
gene id: 223919:F3K33_RS06480
uniprot id: A0A5P2ETH1
names: Similarity
messages: Belongs to the ribF family.

223919:F3K33 RS06005
gene id: 223919:F3K33_RS06005
uniprot id: A0A5P2ER30
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

223919:F3K33 RS11490
gene id: 223919:F3K33_RS11490
uniprot id: A0A5P2ETN5
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

223919:F3K33 RS25885
gene id: 223919:F3K33_RS25885
uniprot id: A0A5P2F133
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-insensitive subfamily.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force.

223919:F3K33 RS10985
gene id: 223919:F3K33_RS10985
uniprot id: A0A5P2ETM5
names: Similarity
messages: Belongs to the 6-phosphogluconate dehydrogenase family.

223919:F3K33 RS17315
gene id: 223919:F3K33_RS17315
uniprot id: A0A5P2EWJ4
names: Similarity
messages: Belongs to the EamA transporter family.

223919:F3K33 RS12370
gene id: 223919:F3K33_RS12370
uniprot id: A0A5P2EWW6
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

223919:F3K33 RS24585
gene id: 223919:F3K33_RS24585
uniprot id: A0A5P2F3Y6
names: Similarity
messages: Belongs to the hemerythrin family.

223919:F3K33 RS25440
gene id: 223919:F3K33_RS25440
uniprot id: A0A5P2F803
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

223919:F3K33 RS15365
gene id: 223919:F3K33_RS15365
uniprot id: A0A5P2EVI8
names: Similarity
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.

223919:F3K33 RS07630
gene id: 223919:F3K33_RS07630
uniprot id: A0A5P2F2S3
names: Subcellular Location Annotation
messages: Membrane

223919:F3K33 RS07090
gene id: 223919:F3K33_RS07090
uniprot id: A0A5P2ETU1
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

223919:F3K33 RS04260
gene id: 223919:F3K33_RS04260
uniprot id: A0A5P2EQA9
names: Similarity
messages: Belongs to the glutathione peroxidase family.

223919:F3K33 RS24235
gene id: 223919:F3K33_RS24235
uniprot id: A0A5P2F6I2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

223919:F3K33 RS06295
gene id: 223919:F3K33_RS06295
uniprot id: A0A5P2F235
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

223919:F3K33 RS01055
gene id: 223919:F3K33_RS01055
uniprot id: A0A5P2ES29
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

223919:F3K33 RS06505
gene id: 223919:F3K33_RS06505
uniprot id: A0A5P2EWU8
names: Function
names: Similarity
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids threonine, isoleucine and methionine.

223919:F3K33 RS00770
gene id: 223919:F3K33_RS00770
uniprot id: A0A5P2ENM7
names: Caution
names: Similarity
messages: Belongs to the ATP:guanido phosphotransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

223919:F3K33 RS16960
gene id: 223919:F3K33_RS16960
uniprot id: A0A5P2EWA1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

223919:F3K33 RS26120
gene id: 223919:F3K33_RS26120
uniprot id: A0A5P2FCC3
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

223919:F3K33 RS15615
gene id: 223919:F3K33_RS15615
uniprot id: A0A5P2F6V7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial solute-binding protein 2 family.
messages: Periplasm
messages: The ABC transporter complex is composed of one ATP-binding protein (MglA), two transmembrane proteins (MglC) and a solute-binding protein (MglB).

223919:F3K33 RS11605
gene id: 223919:F3K33_RS11605
uniprot id: A0A5P2EXE4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

223919:F3K33 RS03625
gene id: 223919:F3K33_RS03625
uniprot id: A0A5P2EV81
names: Subcellular Location Annotation
messages: Membrane

223919:F3K33 RS06060
gene id: 223919:F3K33_RS06060
uniprot id: A0A5P2ER36
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

223919:F3K33 RS09880
gene id: 223919:F3K33_RS09880
uniprot id: A0A5P2ET26
names: Similarity
messages: Belongs to the xanthine dehydrogenase family.

223919:F3K33 RS13980
gene id: 223919:F3K33_RS13980
uniprot id: A0A5P2EV27
names: Similarity
messages: Belongs to the leucine-binding protein family.

223919:F3K33 RS19755
gene id: 223919:F3K33_RS19755
uniprot id: A0A5P2F0D8
names: Subcellular Location Annotation
messages: Membrane

223919:F3K33 RS21350
gene id: 223919:F3K33_RS21350
uniprot id: A0A5P2EYH9
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

223919:F3K33 RS15670
gene id: 223919:F3K33_RS15670
uniprot id: A0A5P2EYK7
names: Similarity
messages: Belongs to the IPP isomerase type 1 family.

223919:F3K33 RS02635
gene id: 223919:F3K33_RS02635
uniprot id: A0A5P2EP98
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acetylates the N-terminal alanine of ribosomal protein S18.
messages: Belongs to the acetyltransferase family. RimI subfamily.
messages: Cytoplasm

223919:F3K33 RS04440
gene id: 223919:F3K33_RS04440
uniprot id: A0A5P2F142
names: Function
names: Similarity
messages: Belongs to the anti-sigma-factor family.
messages: Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.

223919:F3K33 RS02940
gene id: 223919:F3K33_RS02940
uniprot id: A0A5P2ESU9
names: Similarity
messages: Belongs to the UPF0758 family.

223919:F3K33 RS21785
gene id: 223919:F3K33_RS21785
uniprot id: A0A5P2EZA3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliP/MopC/SpaP family.
messages: Cell membrane
messages: Membrane
messages: Plays a role in the flagellum-specific transport system.

223919:F3K33 RS03545
gene id: 223919:F3K33_RS03545
uniprot id: A0A5P2ERL2
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the NifH/BchL/ChlL family.
messages: Binds 1 [4Fe-4S] cluster per dimer.
messages: Homodimer.
messages: The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein.
messages: The reversible ADP-ribosylation of Arg inactivates the nitrogenase reductase and regulates nitrogenase activity.
messages: The reversible ADP-ribosylation of Arg-102 inactivates the nitrogenase reductase and regulates nitrogenase activity.

223919:F3K33 RS04510
gene id: 223919:F3K33_RS04510
uniprot id: A0A5P2EQC2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

223919:F3K33 RS11280
gene id: 223919:F3K33_RS11280
uniprot id: A0A5P2ETP8
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

223919:F3K33 RS24115
gene id: 223919:F3K33_RS24115
uniprot id: A0A5P2FBC2
names: Subcellular Location Annotation
messages: Membrane
messages: Nucleus membrane

223919:F3K33 RS13390
gene id: 223919:F3K33_RS13390
uniprot id: A0A5P2EUS2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

223919:F3K33 RS00965
gene id: 223919:F3K33_RS00965
uniprot id: A0A5P2ETW1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

223919:F3K33 RS10690
gene id: 223919:F3K33_RS10690
uniprot id: A0A5P2EW16
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

223919:F3K33 RS05650
gene id: 223919:F3K33_RS05650
uniprot id: A0A5P2EUC1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

223919:F3K33 RS05410
gene id: 223919:F3K33_RS05410
uniprot id: A0A5P2EW65
names: Similarity
messages: Belongs to the CvfB family.

223919:F3K33 RS17115
gene id: 223919:F3K33_RS17115
uniprot id: A0A5P2F2U2
names: Similarity
messages: Belongs to the LacAB/RpiB family.

223919:F3K33 RS03350
gene id: 223919:F3K33_RS03350
uniprot id: A0A5P2ET69
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Clade 'B2' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Non-allosteric.

223919:F3K33 RS08270
gene id: 223919:F3K33_RS08270
uniprot id: A0A5P2EVP5
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

223919:F3K33 RS24790
gene id: 223919:F3K33_RS24790
uniprot id: A0A5P2F4V5
names: Similarity
messages: Belongs to the CbxX/CfxQ family.

223919:F3K33 RS20355
gene id: 223919:F3K33_RS20355
uniprot id: A0A5P2ET81
names: Function
names: Similarity
messages: Belongs to the transposase 11 family.
messages: Involved in the transposition of the insertion sequence IS5.

223919:F3K33 RS04015
gene id: 223919:F3K33_RS04015
uniprot id: A0A5P2EQ36
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

223919:F3K33 RS16395
gene id: 223919:F3K33_RS16395
uniprot id: A0A5P2EW59
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chloramphenicol acetyltransferase family.
messages: Homotrimer.
messages: This enzyme is an effector of chloramphenicol resistance in bacteria.

223919:F3K33 RS06345
gene id: 223919:F3K33_RS06345
uniprot id: A0A5P2F240
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

223919:F3K33 RS21260
gene id: 223919:F3K33_RS21260
uniprot id: A0A5P2EYR6
names: Similarity
messages: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family.

223919:F3K33 RS15635
gene id: 223919:F3K33_RS15635
uniprot id: A0A5P2EW26
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

223919:F3K33 RS23160
gene id: 223919:F3K33_RS23160
uniprot id: A0A5P2EZM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YejK family.
messages: nucleoid

223919:F3K33 RS21285
gene id: 223919:F3K33_RS21285
uniprot id: A0A5P2F9V8
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

223919:F3K33 RS08980
gene id: 223919:F3K33_RS08980
uniprot id: A0A5P2F3G1
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

223919:F3K33 RS12950
gene id: 223919:F3K33_RS12950
uniprot id: A0A5P2EX66
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

223919:F3K33 RS02980
gene id: 223919:F3K33_RS02980
uniprot id: A0A5P2EPF5
names: Function
names: Similarity
messages: Belongs to the MinE family.
messages: Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.

223919:F3K33 RS04235
gene id: 223919:F3K33_RS04235
uniprot id: A0A5P2F101
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

223919:F3K33 RS26110
gene id: 223919:F3K33_RS26110
uniprot id: A0A5P2F4P7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

223919:F3K33 RS21970
gene id: 223919:F3K33_RS21970
uniprot id: A0A5P2F1U9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'-UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

223919:F3K33 RS25495
gene id: 223919:F3K33_RS25495
uniprot id: A0A5P2F583
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

223919:F3K33 RS25015
gene id: 223919:F3K33_RS25015
uniprot id: A0A5P2F3K6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Belongs to the P-Pant transferase superfamily. Gsp/Sfp/HetI/AcpT family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

223919:F3K33 RS00115
gene id: 223919:F3K33_RS00115
uniprot id: A0A5P2EN52
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. AddA subfamily.
messages: Heterodimer of AddA and AddB/RexB.
messages: The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation; this subunit has the helicase and 3' -> 5' nuclease activities.

223919:F3K33 RS17000
gene id: 223919:F3K33_RS17000
uniprot id: A0A5P2F7J2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial solute-binding protein 2 family.
messages: Periplasm
messages: The ABC transporter complex is composed of one ATP-binding protein (MglA), two transmembrane proteins (MglC) and a solute-binding protein (MglB).

223919:F3K33 RS21650
gene id: 223919:F3K33_RS21650
uniprot id: A0A5P2F2E9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

223919:F3K33 RS15230
gene id: 223919:F3K33_RS15230
uniprot id: A0A5P2EZ66
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit C family.
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

223919:F3K33 RS07795
gene id: 223919:F3K33_RS07795
uniprot id: A0A5P2ES22
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

223919:F3K33 RS26075
gene id: 223919:F3K33_RS26075
uniprot id: A0A5P2F449
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

223919:F3K33 RS05545
gene id: 223919:F3K33_RS05545
uniprot id: A0A5P2EUA5
names: Caution
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

223919:F3K33 RS13000
gene id: 223919:F3K33_RS13000
uniprot id: A0A5P2EX75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

223919:F3K33 RS02245
gene id: 223919:F3K33_RS02245
uniprot id: A0A5P2EP27
names: Similarity
messages: Belongs to the glutathione peroxidase family.

223919:F3K33 RS06485
gene id: 223919:F3K33_RS06485
uniprot id: A0A5P2EUS4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

223919:F3K33 RS19190
gene id: 223919:F3K33_RS19190
uniprot id: A0A5P2EXP7
names: Similarity
messages: Belongs to the hemerythrin family.

223919:F3K33 RS11320
gene id: 223919:F3K33_RS11320
uniprot id: A0A5P2ETK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

223919:F3K33 RS21985
gene id: 223919:F3K33_RS21985
uniprot id: A0A5P2EZF2
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

223919:F3K33 RS13225
gene id: 223919:F3K33_RS13225
uniprot id: A0A5P2EXA3
names: Similarity
messages: Belongs to the TPP enzyme family.

223919:F3K33 RS07160
gene id: 223919:F3K33_RS07160
uniprot id: A0A5P2F2J1
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

223919:F3K33 RS11685
gene id: 223919:F3K33_RS11685
uniprot id: A0A5P2EZP0
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type II sub-subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The autoendoproteolytic cleavage occurs by a canonical serine protease mechanism, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain. During this reaction, the Ser that is part of the protease active site of the proenzyme becomes the pyruvoyl prosthetic group, which constitutes an essential element of the active site of the mature decarboxylase.

223919:F3K33 RS24070
gene id: 223919:F3K33_RS24070
uniprot id: A0A5P2F6F3
names: Subcellular Location Annotation
messages: Membrane

223919:F3K33 RS10990
gene id: 223919:F3K33_RS10990
uniprot id: A0A5P2ETM1
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

223919:F3K33 RS06100
gene id: 223919:F3K33_RS06100
uniprot id: A0A5P2EWL3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

223919:F3K33 RS06430
gene id: 223919:F3K33_RS06430
uniprot id: A0A5P2ETG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

223919:F3K33 RS05535
gene id: 223919:F3K33_RS05535
uniprot id: A0A5P2EQW0
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

223919:F3K33 RS24405
gene id: 223919:F3K33_RS24405
uniprot id: A0A5P2F0F3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

223919:F3K33 RS15400
gene id: 223919:F3K33_RS15400
uniprot id: A0A5P2EZQ5
names: Similarity
messages: In the N-terminal section; belongs to the zinc metallo-hydrolase group 3 family.

223919:F3K33 RS04225
gene id: 223919:F3K33_RS04225
uniprot id: A0A5P2ETH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

223919:F3K33 RS02620
gene id: 223919:F3K33_RS02620
uniprot id: A0A5P2F055
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic riboflavin transporter (P-RFT) (TC 2.A.87) family.
messages: Cell membrane
messages: Membrane
messages: Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex.

223919:F3K33 RS08065
gene id: 223919:F3K33_RS08065
uniprot id: A0A5P2EVK6
names: Caution
names: Function
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

223919:F3K33 RS05345
gene id: 223919:F3K33_RS05345
uniprot id: A0A5P2ET87
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

223919:F3K33 RS20480
gene id: 223919:F3K33_RS20480
uniprot id: A0A5P2F1Q9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

223919:F3K33 RS09290
gene id: 223919:F3K33_RS09290
uniprot id: A0A5P2EYE7
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

223919:F3K33 RS21335
gene id: 223919:F3K33_RS21335
uniprot id: A0A5P2F9W8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

223919:F3K33 RS23600
gene id: 223919:F3K33_RS23600
uniprot id: A0A5P2FB27
names: Cofactor
messages: Binds 1 Mg(2+) ion per trimer.

223919:F3K33 RS06525
gene id: 223919:F3K33_RS06525
uniprot id: A0A5P2ERD7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane
messages: This protein catalyzes the committed step to the synthesis of the acidic phospholipids.

223919:F3K33 RS16235
gene id: 223919:F3K33_RS16235
uniprot id: A0A5P2EW70
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

223919:F3K33 RS06515
gene id: 223919:F3K33_RS06515
uniprot id: A0A5P2ERB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Membrane

223919:F3K33 RS22240
gene id: 223919:F3K33_RS22240
uniprot id: A0A5P2EZK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

223919:F3K33 RS14575
gene id: 223919:F3K33_RS14575
uniprot id: A0A5P2EZA4
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

223919:F3K33 RS08835
gene id: 223919:F3K33_RS08835
uniprot id: A0A5P2EY57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

223919:F3K33 RS25200
gene id: 223919:F3K33_RS25200
uniprot id: A0A5P2F492
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LDH/MDH superfamily. LDH family.
messages: Catalyzes the conversion of lactate to pyruvate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

223919:F3K33 RS01945
gene id: 223919:F3K33_RS01945
uniprot id: A0A5P2EQT4
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

223919:F3K33 RS06225
gene id: 223919:F3K33_RS06225
uniprot id: A0A5P2ER76
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

223919:F3K33 RS24285
gene id: 223919:F3K33_RS24285
uniprot id: A0A5P2F6J1
names: Subcellular Location Annotation
messages: Membrane

223919:F3K33 RS00625
gene id: 223919:F3K33_RS00625
uniprot id: A0A5P2ENS2
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

223919:F3K33 RS24440
gene id: 223919:F3K33_RS24440
uniprot id: A0A5P2F384
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

223919:F3K33 RS09645
gene id: 223919:F3K33_RS09645
uniprot id: A0A5P2EVG6
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20 family.
messages: Binds 2 Zn(2+) ions per subunit.

223919:F3K33 RS06545
gene id: 223919:F3K33_RS06545
uniprot id: A0A5P2F282
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The phosphoryl group from phosphoenolpyruvate (PEP) is transferred to the phosphoryl carrier protein HPr by enzyme I. Phospho-HPr then transfers it to the PTS EIIA domain.

223919:F3K33 RS19600
gene id: 223919:F3K33_RS19600
uniprot id: A0A5P2F8Y7
names: Function
names: Similarity
messages: Belongs to the ADC family.
messages: Catalyzes the conversion of acetoacetate to acetone and carbon dioxide.

223919:F3K33 RS13505
gene id: 223919:F3K33_RS13505
uniprot id: A0A5P2EUT8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

223919:F3K33 RS05090
gene id: 223919:F3K33_RS05090
uniprot id: A0A5P2F1F5
names: Subcellular Location Annotation
messages: Membrane

223919:F3K33 RS11850
gene id: 223919:F3K33_RS11850
uniprot id: A0A5P2EU04
names: Function
names: Similarity
names: Subunit
messages: Belongs to the precorrin methyltransferase family.
messages: Homodimer.
messages: Methylates cobalt-precorrin-2 at the C-20 position to produce cobalt-precorrin-3A in the anaerobic cobalamin biosynthesis pathway.

223919:F3K33 RS14535
gene id: 223919:F3K33_RS14535
uniprot id: A0A5P2F1D5
names: Similarity
messages: Belongs to the TPP enzyme family.

223919:F3K33 RS20935
gene id: 223919:F3K33_RS20935
uniprot id: A0A5P2F4R9
names: Cofactor
messages: Binds 1 zinc ion per subunit.

223919:F3K33 RS06240
gene id: 223919:F3K33_RS06240
uniprot id: A0A5P2EUV5
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

223919:F3K33 RS17450
gene id: 223919:F3K33_RS17450
uniprot id: A0A5P2F0B0
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

223919:F3K33 RS09315
gene id: 223919:F3K33_RS09315
uniprot id: A0A5P2ESQ7
names: Similarity
messages: Belongs to the peptidase S11 family.

223919:F3K33 RS11485
gene id: 223919:F3K33_RS11485
uniprot id: A0A5P2EZL0
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

223919:F3K33 RS03845
gene id: 223919:F3K33_RS03845
uniprot id: A0A5P2ESE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ribonuclease N1/T1 family.
messages: Secreted

223919:F3K33 RS07505
gene id: 223919:F3K33_RS07505
uniprot id: A0A5P2ERU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

223919:F3K33 RS08720
gene id: 223919:F3K33_RS08720
uniprot id: A0A5P2EW49
names: Function
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

223919:F3K33 RS10855
gene id: 223919:F3K33_RS10855
uniprot id: A0A5P2EXF3
names: Similarity
messages: Belongs to the ArsC family.

223919:F3K33 RS07565
gene id: 223919:F3K33_RS07565
uniprot id: A0A5P2EU39
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system and for the release of the potassium ions to the cytoplasm.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

223919:F3K33 RS06775
gene id: 223919:F3K33_RS06775
uniprot id: A0A5P2ERH2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Membrane

223919:F3K33 RS06300
gene id: 223919:F3K33_RS06300
uniprot id: A0A5P2ETR0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

223919:F3K33 RS23770
gene id: 223919:F3K33_RS23770
uniprot id: A0A5P2F0D5
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

223919:F3K33 RS14850
gene id: 223919:F3K33_RS14850
uniprot id: A0A5P2EVN1
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

223919:F3K33 RS11245
gene id: 223919:F3K33_RS11245
uniprot id: A0A5P2EXM1
names: Similarity
messages: Belongs to the EamA transporter family.

223919:F3K33 RS21110
gene id: 223919:F3K33_RS21110
uniprot id: A0A5P2EYP2
names: Similarity
messages: Belongs to the IlvD/Edd family.

223919:F3K33 RS11915
gene id: 223919:F3K33_RS11915
uniprot id: A0A5P2EXI4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

223919:F3K33 RS25450
gene id: 223919:F3K33_RS25450
uniprot id: A0A5P2F3U2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

223919:F3K33 RS10590
gene id: 223919:F3K33_RS10590
uniprot id: A0A5P2EVZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Cell membrane
messages: Membrane

223919:F3K33 RS03540
gene id: 223919:F3K33_RS03540
uniprot id: A0A5P2EPQ1
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

223919:F3K33 RS25065
gene id: 223919:F3K33_RS25065
uniprot id: A0A5P2F3M1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

223919:F3K33 RS21470
gene id: 223919:F3K33_RS21470
uniprot id: A0A5P2EYV7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

223919:F3K33 RS22100
gene id: 223919:F3K33_RS22100
uniprot id: A0A5P2EZ22
names: Similarity
messages: Belongs to the RecJ family.

223919:F3K33 RS15630
gene id: 223919:F3K33_RS15630
uniprot id: A0A5P2EVN2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial solute-binding protein 2 family.
messages: Periplasm
messages: The ABC transporter complex is composed of one ATP-binding protein (MglA), two transmembrane proteins (MglC) and a solute-binding protein (MglB).

223919:F3K33 RS23295
gene id: 223919:F3K33_RS23295
uniprot id: A0A5P2EZJ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

223919:F3K33 RS00435
gene id: 223919:F3K33_RS00435
uniprot id: A0A5P2EQ13
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

223919:F3K33 RS01440
gene id: 223919:F3K33_RS01440
uniprot id: A0A5P2ENQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

223919:F3K33 RS06125
gene id: 223919:F3K33_RS06125
uniprot id: A0A5P2ET99
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

223919:F3K33 RS05995
gene id: 223919:F3K33_RS05995
uniprot id: A0A5P2EWJ8
names: Similarity
messages: Belongs to the Fur family.

223919:F3K33 RS01115
gene id: 223919:F3K33_RS01115
uniprot id: A0A5P2ER48
names: Similarity
messages: Belongs to the class-I fumarase family.

223919:F3K33 RS12105
gene id: 223919:F3K33_RS12105
uniprot id: A0A5P2EU24
names: Function
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. NagD family.
messages: Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro.

223919:F3K33 RS07100
gene id: 223919:F3K33_RS07100
uniprot id: A0A5P2EVA7
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

223919:F3K33 RS12745
gene id: 223919:F3K33_RS12745
uniprot id: A0A5P2F5F9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial solute-binding protein 2 family.
messages: Periplasm
messages: The ABC transporter complex is composed of one ATP-binding protein (MglA), two transmembrane proteins (MglC) and a solute-binding protein (MglB).

223919:F3K33 RS21735
gene id: 223919:F3K33_RS21735
uniprot id: A0A5P2EZ93
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

223919:F3K33 RS04665
gene id: 223919:F3K33_RS04665
uniprot id: A0A5P2EVS4
names: Similarity
messages: Belongs to the peptidase S8 family.

223919:F3K33 RS20050
gene id: 223919:F3K33_RS20050
uniprot id: A0A5P2F0I1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Cell membrane
messages: Membrane

223919:F3K33 RS17600
gene id: 223919:F3K33_RS17600
uniprot id: A0A5P2F7S1
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

223919:F3K33 RS03890
gene id: 223919:F3K33_RS03890
uniprot id: A0A5P2F0U5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

223919:F3K33 RS04920
gene id: 223919:F3K33_RS04920
uniprot id: A0A5P2ETW8
names: Similarity
messages: Belongs to the glycosyl hydrolase 25 family.

223919:F3K33 RS01075
gene id: 223919:F3K33_RS01075
uniprot id: A0A5P2ENI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane

223919:F3K33 RS18910
gene id: 223919:F3K33_RS18910
uniprot id: A0A5P2F3Q2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ApbE family.
messages: Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.
messages: Magnesium. Can also use manganese.

223919:F3K33 RS10845
gene id: 223919:F3K33_RS10845
uniprot id: A0A5P2EW57
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

223919:F3K33 RS21910
gene id: 223919:F3K33_RS21910
uniprot id: A0A5P2F3C2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

223919:F3K33 RS05300
gene id: 223919:F3K33_RS05300
uniprot id: A0A5P2EW43
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Belongs to the organic radical-activating enzymes family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm

223919:F3K33 RS06395
gene id: 223919:F3K33_RS06395
uniprot id: A0A5P2F254
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

223919:F3K33 RS02610
gene id: 223919:F3K33_RS02610
uniprot id: A0A5P2ESP6
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

223919:F3K33 RS01505
gene id: 223919:F3K33_RS01505
uniprot id: A0A5P2ENZ8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

223919:F3K33 RS20715
gene id: 223919:F3K33_RS20715
uniprot id: A0A5P2F165
names: Similarity
messages: Belongs to the bacterial microcompartments protein family.

223919:F3K33 RS25480
gene id: 223919:F3K33_RS25480
uniprot id: A0A5P2F0V3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane

223919:F3K33 RS05140
gene id: 223919:F3K33_RS05140
uniprot id: A0A5P2F1G6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

223919:F3K33 RS04760
gene id: 223919:F3K33_RS04760
uniprot id: A0A5P2ESX1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Catalyzes the sodium-dependent uptake of extracellular L-proline.
messages: Cell membrane
messages: Membrane

223919:F3K33 RS07915
gene id: 223919:F3K33_RS07915
uniprot id: A0A5P2EVP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

223919:F3K33 RS01245
gene id: 223919:F3K33_RS01245
uniprot id: A0A5P2ENV8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

223919:F3K33 RS05540
gene id: 223919:F3K33_RS05540
uniprot id: A0A5P2ET00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

223919:F3K33 RS11830
gene id: 223919:F3K33_RS11830
uniprot id: A0A5P2EWK3
names: Similarity
messages: Belongs to the CobH/CbiC family.

223919:F3K33 RS06275
gene id: 223919:F3K33_RS06275
uniprot id: A0A5P2ER86
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

223919:F3K33 RS22695
gene id: 223919:F3K33_RS22695
uniprot id: A0A5P2F2Z1
names: Subcellular Location Annotation
messages: Membrane

223919:F3K33 RS12415
gene id: 223919:F3K33_RS12415
uniprot id: A0A5P2EU79
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20B family.
messages: Binds 2 Zn(2+) ions per subunit.

223919:F3K33 RS18440
gene id: 223919:F3K33_RS18440
uniprot id: A0A5P2EXH6
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

223919:F3K33 RS08245
gene id: 223919:F3K33_RS08245
uniprot id: A0A5P2ES02
names: Similarity
messages: Belongs to the YggT family.

223919:F3K33 RS15860
gene id: 223919:F3K33_RS15860
uniprot id: A0A5P2EZI9
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

223919:F3K33 RS06790
gene id: 223919:F3K33_RS06790
uniprot id: A0A5P2EV59
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobD/CbiB family.
messages: Cell membrane
messages: Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
messages: Membrane

223919:F3K33 RS09235
gene id: 223919:F3K33_RS09235
uniprot id: A0A5P2EV92
names: Function
names: Similarity
names: Subunit
messages: In the N-terminal section; belongs to the glutamate--cysteine ligase type 1 family. Type 2 subfamily.
messages: Monomer.
messages: Synthesizes glutathione from L-glutamate and L-cysteine via gamma-L-glutamyl-L-cysteine.

223919:F3K33 RS24280
gene id: 223919:F3K33_RS24280
uniprot id: A0A5P2F351
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

223919:F3K33 RS06845
gene id: 223919:F3K33_RS06845
uniprot id: A0A5P2F2D3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MetA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

223919:F3K33 RS01185
gene id: 223919:F3K33_RS01185
uniprot id: A0A5P2ENK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetokinase family.
messages: Cytoplasm

223919:F3K33 RS02115
gene id: 223919:F3K33_RS02115
uniprot id: A0A5P2EUG1
names: Similarity
messages: Belongs to the peptidase M13 family.

223919:F3K33 RS20535
gene id: 223919:F3K33_RS20535
uniprot id: A0A5P2F1S5
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

223919:F3K33 RS21010
gene id: 223919:F3K33_RS21010
uniprot id: A0A5P2F106
names: Similarity
messages: Belongs to the DtxR/MntR family.

223919:F3K33 RS07195
gene id: 223919:F3K33_RS07195
uniprot id: A0A5P2ETW6
names: Subcellular Location Annotation
messages: Membrane

223919:F3K33 RS23930
gene id: 223919:F3K33_RS23930
uniprot id: A0A5P2F061
names: Subcellular Location Annotation
messages: Membrane

223919:F3K33 RS12380
gene id: 223919:F3K33_RS12380
uniprot id: A0A5P2EY55
names: Similarity
messages: Belongs to the iron-containing alcohol dehydrogenase family.

223919:F3K33 RS06075
gene id: 223919:F3K33_RS06075
uniprot id: A0A5P2ET91
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

223919:F3K33 RS18865
gene id: 223919:F3K33_RS18865
uniprot id: A0A5P2EX80
names: Subcellular Location Annotation
messages: Membrane

223919:F3K33 RS00175
gene id: 223919:F3K33_RS00175
uniprot id: A0A5P2EPW5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

223919:F3K33 RS08195
gene id: 223919:F3K33_RS08195
uniprot id: A0A5P2ERZ3
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

223919:F3K33 RS25925
gene id: 223919:F3K33_RS25925
uniprot id: A0A5P2F1M0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

223919:F3K33 RS08985
gene id: 223919:F3K33_RS08985
uniprot id: A0A5P2EV52
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

223919:F3K33 RS01535
gene id: 223919:F3K33_RS01535
uniprot id: A0A5P2EZN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

223919:F3K33 RS01655
gene id: 223919:F3K33_RS01655
uniprot id: A0A5P2ENU3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

223919:F3K33 RS12975
gene id: 223919:F3K33_RS12975
uniprot id: A0A5P2F0E9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

223919:F3K33 RS08160
gene id: 223919:F3K33_RS08160
uniprot id: A0A5P2EUF7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

223919:F3K33 RS00655
gene id: 223919:F3K33_RS00655
uniprot id: A0A5P2ERS6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

223919:F3K33 RS22215
gene id: 223919:F3K33_RS22215
uniprot id: A0A5P2F3H8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

223919:F3K33 RS16665
gene id: 223919:F3K33_RS16665
uniprot id: A0A5P2F2L9
names: Function
names: Similarity
messages: Belongs to the alpha/beta-type SASP family.
messages: SASP are bound to spore DNA. They are double-stranded DNA-binding proteins that cause DNA to change to an a-like conformation. They protect the DNA backbone from chemical and enzymatic cleavage and are thus involved in dormant spore's high resistance to UV light.

223919:F3K33 RS02790
gene id: 223919:F3K33_RS02790
uniprot id: A0A5P2F083
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the selenophosphate synthase 1 family. Class I subfamily.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Homodimer.
messages: Synthesizes selenophosphate from selenide and ATP.

223919:F3K33 RS13355
gene id: 223919:F3K33_RS13355
uniprot id: A0A5P2EXF0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

223919:F3K33 RS25240
gene id: 223919:F3K33_RS25240
uniprot id: A0A5P2F714
names: Subcellular Location Annotation
messages: Cytoplasm

223919:F3K33 RS25720
gene id: 223919:F3K33_RS25720
uniprot id: A0A5P2F3Z8
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

223919:F3K33 RS06375
gene id: 223919:F3K33_RS06375
uniprot id: A0A5P2ERA4
names: Similarity
messages: Belongs to the DprA/Smf family.

223919:F3K33 RS02945
gene id: 223919:F3K33_RS02945
uniprot id: A0A5P2ESZ2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

223919:F3K33 RS02615
gene id: 223919:F3K33_RS02615
uniprot id: A0A5P2EST8
names: Similarity
messages: Belongs to the hemerythrin family.

223919:F3K33 RS25400
gene id: 223919:F3K33_RS25400
uniprot id: A0A5P2F739
names: Similarity
messages: Belongs to the peptidase M13 family.

223919:F3K33 RS18760
gene id: 223919:F3K33_RS18760
uniprot id: A0A5P2EXN9
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

223919:F3K33 RS09045
gene id: 223919:F3K33_RS09045
uniprot id: A0A5P2ESE1
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

223919:F3K33 RS24265
gene id: 223919:F3K33_RS24265
uniprot id: A0A5P2F3S5
names: Similarity
messages: Belongs to the ABC transporter superfamily.

223919:F3K33 RS02395
gene id: 223919:F3K33_RS02395
uniprot id: A0A5P2EP57
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

223919:F3K33 RS09625
gene id: 223919:F3K33_RS09625
uniprot id: A0A5P2ESQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

223919:F3K33 RS22840
gene id: 223919:F3K33_RS22840
uniprot id: A0A5P2EZG1
names: Subcellular Location Annotation
messages: Membrane

223919:F3K33 RS00605
gene id: 223919:F3K33_RS00605
uniprot id: A0A5P2EQW4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

223919:F3K33 RS14965
gene id: 223919:F3K33_RS14965
uniprot id: A0A5P2EY67
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

223919:F3K33 RS24520
gene id: 223919:F3K33_RS24520
uniprot id: A0A5P2F0C4
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 4 family.
messages: Binds 1 NAD(+) per subunit.
messages: Homotetramer.

223919:F3K33 RS06150
gene id: 223919:F3K33_RS06150
uniprot id: A0A5P2EWM6
names: Similarity
messages: Belongs to the RemA family.

223919:F3K33 RS17090
gene id: 223919:F3K33_RS17090
uniprot id: A0A5P2F056
names: Subcellular Location Annotation
messages: Membrane

223919:F3K33 RS20360
gene id: 223919:F3K33_RS20360
uniprot id: A0A5P2EYH7
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

223919:F3K33 RS13900
gene id: 223919:F3K33_RS13900
uniprot id: A0A5P2EYJ4
names: Cofactor
names: Similarity
messages: Belongs to the iron-containing alcohol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.

223919:F3K33 RS21815
gene id: 223919:F3K33_RS21815
uniprot id: A0A5P2FA74
names: Function
names: Similarity
messages: Belongs to the FlgD family.
messages: Required for flagellar hook formation. May act as a scaffolding protein.

223919:F3K33 RS21425
gene id: 223919:F3K33_RS21425
uniprot id: A0A5P2EYN2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PAPS reductase family. CysD subfamily.
messages: Heterodimer composed of CysD, the smaller subunit, and CysN.
messages: With CysN forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.

223919:F3K33 RS11600
gene id: 223919:F3K33_RS11600
uniprot id: A0A5P2EWH3
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

223919:F3K33 RS04085
gene id: 223919:F3K33_RS04085
uniprot id: A0A5P2ERX7
names: Subcellular Location Annotation
messages: Membrane

223919:F3K33 RS14920
gene id: 223919:F3K33_RS14920
uniprot id: A0A5P2EVP0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

223919:F3K33 RS20590
gene id: 223919:F3K33_RS20590
uniprot id: A0A5P2F2H4
names: Similarity
messages: Belongs to the EamA transporter family.

223919:F3K33 RS21035
gene id: 223919:F3K33_RS21035
uniprot id: A0A5P2F4T9
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

223919:F3K33 RS24185
gene id: 223919:F3K33_RS24185
uniprot id: A0A5P2F0L8
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

223919:F3K33 RS13305
gene id: 223919:F3K33_RS13305
uniprot id: A0A5P2EXD8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

223919:F3K33 RS19375
gene id: 223919:F3K33_RS19375
uniprot id: A0A5P2F8N1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

223919:F3K33 RS12855
gene id: 223919:F3K33_RS12855
uniprot id: A0A5P2F5H5
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

223919:F3K33 RS07615
gene id: 223919:F3K33_RS07615
uniprot id: A0A5P2EU48
names: Cofactor
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.

223919:F3K33 RS08650
gene id: 223919:F3K33_RS08650
uniprot id: A0A5P2EW39
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

223919:F3K33 RS24120
gene id: 223919:F3K33_RS24120
uniprot id: A0A5P2F323
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

223919:F3K33 RS03820
gene id: 223919:F3K33_RS03820
uniprot id: A0A5P2ERS3
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

223919:F3K33 RS12055
gene id: 223919:F3K33_RS12055
uniprot id: A0A5P2EU15
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

223919:F3K33 RS15345
gene id: 223919:F3K33_RS15345
uniprot id: A0A5P2EZP5
names: Similarity
messages: Belongs to the HupF/HypC family.

223919:F3K33 RS23755
gene id: 223919:F3K33_RS23755
uniprot id: A0A5P2F2W1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LTA synthase family.
messages: Cell membrane
messages: Membrane

223919:F3K33 RS06760
gene id: 223919:F3K33_RS06760
uniprot id: A0A5P2ER94
names: Function
names: Similarity
messages: Belongs to the CobT family.
messages: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).

223919:F3K33 RS10030
gene id: 223919:F3K33_RS10030
uniprot id: A0A5P2ET46
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

223919:F3K33 RS19520
gene id: 223919:F3K33_RS19520
uniprot id: A0A5P2EXN5
names: Similarity
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

223919:F3K33 RS23695
gene id: 223919:F3K33_RS23695
uniprot id: A0A5P2F4A1
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

223919:F3K33 RS00370
gene id: 223919:F3K33_RS00370
uniprot id: A0A5P2ENH4
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

223919:F3K33 RS00010
gene id: 223919:F3K33_RS00010
uniprot id: A0A5P2ENC7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

223919:F3K33 RS06365
gene id: 223919:F3K33_RS06365
uniprot id: A0A5P2ER89
names: Similarity
messages: Belongs to the UPF0102 family.

223919:F3K33 RS09180
gene id: 223919:F3K33_RS09180
uniprot id: A0A5P2F3K4
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.

223919:F3K33 RS05250
gene id: 223919:F3K33_RS05250
uniprot id: A0A5P2EW34
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

223919:F3K33 RS08745
gene id: 223919:F3K33_RS08745
uniprot id: A0A5P2ESF8
names: Subcellular Location Annotation
messages: Membrane

223919:F3K33 RS16570
gene id: 223919:F3K33_RS16570
uniprot id: A0A5P2EWD2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

223919:F3K33 RS24135
gene id: 223919:F3K33_RS24135
uniprot id: A0A5P2F0K7
names: Similarity
messages: Belongs to the glycosyl hydrolase 66 family.

223919:F3K33 RS00365
gene id: 223919:F3K33_RS00365
uniprot id: A0A5P2EN93
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

223919:F3K33 RS22150
gene id: 223919:F3K33_RS22150
uniprot id: A0A5P2EZ32
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family.
messages: Cell membrane
messages: Membrane
messages: O-acyltransferase that catalyzes D-alanylation of both teichoic acid and lipoteichoic acid (LTA). D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall. Catalyzes D-alanylation from DltC carrier protein.

223919:F3K33 RS05550
gene id: 223919:F3K33_RS05550
uniprot id: A0A5P2EUH2
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

223919:F3K33 RS02265
gene id: 223919:F3K33_RS02265
uniprot id: A0A5P2EQX6
names: Function
names: Similarity
names: Subunit
messages: Catalyzes the ATP-dependent polymerization of arginine and aspartate to multi-L-arginyl-poly-L-aspartic acid (cyanophycin; a water-insoluble reserve polymer).
messages: Homodimer.
messages: In the C-terminal section; belongs to the MurCDEF family.

223919:F3K33 RS02320
gene id: 223919:F3K33_RS02320
uniprot id: A0A5P2ESK2
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

223919:F3K33 RS00960
gene id: 223919:F3K33_RS00960
uniprot id: A0A5P2ER18
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

223919:F3K33 RS06895
gene id: 223919:F3K33_RS06895
uniprot id: A0A5P2F2E2
names: Function
names: Similarity
messages: Belongs to the QueH family.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).

223919:F3K33 RS06385
gene id: 223919:F3K33_RS06385
uniprot id: A0A5P2EUQ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CodY family.
messages: Cytoplasm
messages: DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor.

223919:F3K33 RS02375
gene id: 223919:F3K33_RS02375
uniprot id: A0A5P2ESQ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

223919:F3K33 RS15815
gene id: 223919:F3K33_RS15815
uniprot id: A0A5P2EZY7
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

223919:F3K33 RS00975
gene id: 223919:F3K33_RS00975
uniprot id: A0A5P2ENR1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

223919:F3K33 RS03320
gene id: 223919:F3K33_RS03320
uniprot id: A0A5P2EPS0
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

223919:F3K33 RS04380
gene id: 223919:F3K33_RS04380
uniprot id: A0A5P2ETR7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
messages: Single-chain monomer with multiple functions.

223919:F3K33 RS03030
gene id: 223919:F3K33_RS03030
uniprot id: A0A5P2EPG4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

223919:F3K33 RS16035
gene id: 223919:F3K33_RS16035
uniprot id: A0A5P2EYS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily.
messages: Cell membrane

223919:F3K33 RS00880
gene id: 223919:F3K33_RS00880
uniprot id: A0A5P2ENV5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

223919:F3K33 RS07260
gene id: 223919:F3K33_RS07260
uniprot id: A0A5P2EVD5
names: Similarity
messages: Belongs to the UPF0473 family.

223919:F3K33 RS00020
gene id: 223919:F3K33_RS00020
uniprot id: A0A5P2EN39
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

223919:F3K33 RS04600
gene id: 223919:F3K33_RS04600
uniprot id: A0A5P2ESU2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

223919:F3K33 RS21510
gene id: 223919:F3K33_RS21510
uniprot id: A0A5P2EYK8
names: Similarity
messages: Belongs to the glutamate synthase family.

223919:F3K33 RS23545
gene id: 223919:F3K33_RS23545
uniprot id: A0A5P2F472
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

223919:F3K33 RS20730
gene id: 223919:F3K33_RS20730
uniprot id: A0A5P2EYQ2
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

223919:F3K33 RS09090
gene id: 223919:F3K33_RS09090
uniprot id: A0A5P2EYA9
names: Similarity
messages: Belongs to the mannitol dehydrogenase family. UxaB subfamily.

223919:F3K33 RS09335
gene id: 223919:F3K33_RS09335
uniprot id: A0A5P2F3N2
names: Subcellular Location Annotation
messages: Membrane

223919:F3K33 RS24155
gene id: 223919:F3K33_RS24155
uniprot id: A0A5P2F3Q9
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

223919:F3K33 RS02385
gene id: 223919:F3K33_RS02385
uniprot id: A0A5P2ERP0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

223919:F3K33 RS05740
gene id: 223919:F3K33_RS05740
uniprot id: A0A5P2EQZ4
names: Subcellular Location Annotation
messages: Membrane

223919:F3K33 RS07105
gene id: 223919:F3K33_RS07105
uniprot id: A0A5P2F2I2
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

223919:F3K33 RS24470
gene id: 223919:F3K33_RS24470
uniprot id: A0A5P2F2Q0
names: Subcellular Location Annotation
messages: Membrane

223919:F3K33 RS06055
gene id: 223919:F3K33_RS06055
uniprot id: A0A5P2EQW7
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

223919:F3K33 RS09105
gene id: 223919:F3K33_RS09105
uniprot id: A0A5P2ESP9
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

223919:F3K33 RS12050
gene id: 223919:F3K33_RS12050
uniprot id: A0A5P2EU47
names: Subcellular Location Annotation
messages: Membrane

223919:F3K33 RS15515
gene id: 223919:F3K33_RS15515
uniprot id: A0A5P2EYH4
names: Similarity
messages: Belongs to the class I fructose-bisphosphate aldolase family.

223919:F3K33 RS25565
gene id: 223919:F3K33_RS25565
uniprot id: A0A5P2F777
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

223919:F3K33 RS02550
gene id: 223919:F3K33_RS02550
uniprot id: A0A5P2ER32
names: Similarity
messages: Belongs to the EamA transporter family.

223919:F3K33 RS08945
gene id: 223919:F3K33_RS08945
uniprot id: A0A5P2ESC0
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

223919:F3K33 RS03265
gene id: 223919:F3K33_RS03265
uniprot id: A0A5P2EPL0
names: Similarity
messages: Belongs to the UPF0229 family.

223919:F3K33 RS01305
gene id: 223919:F3K33_RS01305
uniprot id: A0A5P2ENN3
names: Subcellular Location Annotation
messages: Membrane

223919:F3K33 RS22985
gene id: 223919:F3K33_RS22985
uniprot id: A0A5P2EZN7
names: Similarity
messages: Belongs to the ThiD family.

223919:F3K33 RS18815
gene id: 223919:F3K33_RS18815
uniprot id: A0A5P2EX67
names: Similarity
messages: Belongs to the peptidase C59 family.

223919:F3K33 RS00810
gene id: 223919:F3K33_RS00810
uniprot id: A0A5P2ETS5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

223919:F3K33 RS03710
gene id: 223919:F3K33_RS03710
uniprot id: A0A5P2ERP8
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

223919:F3K33 RS03395
gene id: 223919:F3K33_RS03395
uniprot id: A0A5P2ET35
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Could methylate the ribose at the nucleotide 34 wobble position in tRNA.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

223919:F3K33 RS03600
gene id: 223919:F3K33_RS03600
uniprot id: A0A5P2F102
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

223919:F3K33 RS15900
gene id: 223919:F3K33_RS15900
uniprot id: A0A5P2EW19
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

223919:F3K33 RS06920
gene id: 223919:F3K33_RS06920
uniprot id: A0A5P2ERM3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

223919:F3K33 RS20545
gene id: 223919:F3K33_RS20545
uniprot id: A0A5P2F9G3
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

223919:F3K33 RS01500
gene id: 223919:F3K33_RS01500
uniprot id: A0A5P2ENR4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

223919:F3K33 RS02200
gene id: 223919:F3K33_RS02200
uniprot id: A0A5P2EP93
names: Cofactor
messages: Binds 1 Mg(2+) ion per trimer.

223919:F3K33 RS02410
gene id: 223919:F3K33_RS02410
uniprot id: A0A5P2EP58
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

223919:F3K33 RS09145
gene id: 223919:F3K33_RS09145
uniprot id: A0A5P2ESG2
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

223919:F3K33 RS12775
gene id: 223919:F3K33_RS12775
uniprot id: A0A5P2EUF0
names: Subcellular Location Annotation
messages: Membrane

223919:F3K33 RS25535
gene id: 223919:F3K33_RS25535
uniprot id: A0A5P2F0W6
names: Subcellular Location Annotation
messages: Membrane

223919:F3K33 RS03870
gene id: 223919:F3K33_RS03870
uniprot id: A0A5P2EPX1
names: Similarity
messages: Belongs to the organic radical-activating enzymes family.

223919:F3K33 RS25360
gene id: 223919:F3K33_RS25360
uniprot id: A0A5P2F199
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

223919:F3K33 RS09055
gene id: 223919:F3K33_RS09055
uniprot id: A0A5P2ESP3
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. SigI subfamily.
messages: Cytoplasm
messages: Interacts with RsgI.
messages: Negatively regulated by the anti-sigma-I factor RsgI.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

223919:F3K33 RS06170
gene id: 223919:F3K33_RS06170
uniprot id: A0A5P2F7L9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

223919:F3K33 RS17250
gene id: 223919:F3K33_RS17250
uniprot id: A0A5P2EZ86
names: Similarity
messages: Belongs to the myoviridae tail sheath protein family.

223919:F3K33 RS18750
gene id: 223919:F3K33_RS18750
uniprot id: A0A5P2F3M4
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.

223919:F3K33 RS24885
gene id: 223919:F3K33_RS24885
uniprot id: A0A5P2F0P0
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

223919:F3K33 RS02295
gene id: 223919:F3K33_RS02295
uniprot id: A0A5P2EP37
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

223919:F3K33 RS23090
gene id: 223919:F3K33_RS23090
uniprot id: A0A5P2F005
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

223919:F3K33 RS01280
gene id: 223919:F3K33_RS01280
uniprot id: A0A5P2ER75
names: Similarity
messages: Belongs to the disproportionating enzyme family.

223919:F3K33 RS15950
gene id: 223919:F3K33_RS15950
uniprot id: A0A5P2EW25
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial solute-binding protein 2 family.
messages: Periplasm
messages: The ABC transporter complex is composed of one ATP-binding protein (MglA), two transmembrane proteins (MglC) and a solute-binding protein (MglB).

223919:F3K33 RS04355
gene id: 223919:F3K33_RS04355
uniprot id: A0A5P2EQ96
names: Similarity
messages: Belongs to the universal stress protein A family.

223919:F3K33 RS21855
gene id: 223919:F3K33_RS21855
uniprot id: A0A5P2F2J7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

223919:F3K33 RS20380
gene id: 223919:F3K33_RS20380
uniprot id: A0A5P2F1N7
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

223919:F3K33 RS01670
gene id: 223919:F3K33_RS01670
uniprot id: A0A5P2ENU5
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

223919:F3K33 RS08830
gene id: 223919:F3K33_RS08830
uniprot id: A0A5P2EV28
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

223919:F3K33 RS26090
gene id: 223919:F3K33_RS26090
uniprot id: A0A5P2F1N5
names: Similarity
messages: Belongs to the peptidase S16 family.

223919:F3K33 RS22710
gene id: 223919:F3K33_RS22710
uniprot id: A0A5P2FAL9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Galactose/methyl galactoside importer (TC 3.A.1.2.3) family.
messages: Cell membrane
messages: Part of the ABC transporter complex MglABC involved in galactose/methyl galactoside import. Responsible for energy coupling to the transport system.
messages: The complex is composed of one ATP-binding protein (MglA), two transmembrane proteins (MglC) and a solute-binding protein (MglB).

223919:F3K33 RS08030
gene id: 223919:F3K33_RS08030
uniprot id: A0A5P2EUN0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

223919:F3K33 RS21310
gene id: 223919:F3K33_RS21310
uniprot id: A0A5P2EYS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family.
messages: Cell membrane
messages: Membrane

223919:F3K33 RS23785
gene id: 223919:F3K33_RS23785
uniprot id: A0A5P2F2D1
names: Subcellular Location Annotation
messages: Membrane

223919:F3K33 RS07680
gene id: 223919:F3K33_RS07680
uniprot id: A0A5P2ES08
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

223919:F3K33 RS20005
gene id: 223919:F3K33_RS20005
uniprot id: A0A5P2F0T1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial solute-binding protein 2 family.
messages: Periplasm
messages: The ABC transporter complex is composed of one ATP-binding protein (MglA), two transmembrane proteins (MglC) and a solute-binding protein (MglB).

223919:F3K33 RS20340
gene id: 223919:F3K33_RS20340
uniprot id: A0A5P2F9C3
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

223919:F3K33 RS19425
gene id: 223919:F3K33_RS19425
uniprot id: A0A5P2F8V7
names: Function
messages: May be involved in the biosynthesis of molybdopterin.

223919:F3K33 RS14800
gene id: 223919:F3K33_RS14800
uniprot id: A0A5P2EVG5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial solute-binding protein 2 family.
messages: Periplasm
messages: The ABC transporter complex is composed of one ATP-binding protein (MglA), two transmembrane proteins (MglC) and a solute-binding protein (MglB).

223919:F3K33 RS06425
gene id: 223919:F3K33_RS06425
uniprot id: A0A5P2ERB2
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

223919:F3K33 RS06555
gene id: 223919:F3K33_RS06555
uniprot id: A0A5P2EWW3
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

223919:F3K33 RS01275
gene id: 223919:F3K33_RS01275
uniprot id: A0A5P2EZJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

223919:F3K33 RS23210
gene id: 223919:F3K33_RS23210
uniprot id: A0A5P2EZN3
names: Similarity
messages: Belongs to the FBPase class 3 family.

223919:F3K33 RS04970
gene id: 223919:F3K33_RS04970
uniprot id: A0A5P2ESM9
names: Similarity
messages: Belongs to the peptidase S11 family.

223919:F3K33 RS02795
gene id: 223919:F3K33_RS02795
uniprot id: A0A5P2ERW1
names: Similarity
messages: Belongs to the FldB/FldC dehydratase alpha/beta subunit family.

223919:F3K33 RS08900
gene id: 223919:F3K33_RS08900
uniprot id: A0A5P2ESI7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

223919:F3K33 RS20495
gene id: 223919:F3K33_RS20495
uniprot id: A0A5P2F125
names: Subcellular Location Annotation
messages: Membrane

223919:F3K33 RS12925
gene id: 223919:F3K33_RS12925
uniprot id: A0A5P2EUC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

223919:F3K33 RS09765
gene id: 223919:F3K33_RS09765
uniprot id: A0A5P2ESR9
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

223919:F3K33 RS22025
gene id: 223919:F3K33_RS22025
uniprot id: A0A5P2F1V9
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

223919:F3K33 RS03180
gene id: 223919:F3K33_RS03180
uniprot id: A0A5P2EPI9
names: Similarity
messages: Belongs to the LacAB/RpiB family.

223919:F3K33 RS24665
gene id: 223919:F3K33_RS24665
uniprot id: A0A5P2F0W0
names: Similarity
messages: Belongs to the manganese catalase family.

223919:F3K33 RS00315
gene id: 223919:F3K33_RS00315
uniprot id: A0A5P2EN84
names: Similarity
messages: Belongs to the peptidase M24B family.

223919:F3K33 RS22735
gene id: 223919:F3K33_RS22735
uniprot id: A0A5P2EZJ1
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

223919:F3K33 RS23715
gene id: 223919:F3K33_RS23715
uniprot id: A0A5P2EZS3
names: Function
names: Similarity
messages: Belongs to the mannonate dehydratase family.
messages: Catalyzes the dehydration of D-mannonate.

223919:F3K33 RS04995
gene id: 223919:F3K33_RS04995
uniprot id: A0A5P2EVY2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
messages: Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
messages: Homodimer.

223919:F3K33 RS01970
gene id: 223919:F3K33_RS01970
uniprot id: A0A5P2EUF2
names: Similarity
messages: Belongs to the HypE family.

223919:F3K33 RS03295
gene id: 223919:F3K33_RS03295
uniprot id: A0A5P2ET61
names: Similarity
messages: Belongs to the diacylglycerol/lipid kinase family.

223919:F3K33 RS00430
gene id: 223919:F3K33_RS00430
uniprot id: A0A5P2ENA2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

223919:F3K33 RS19615
gene id: 223919:F3K33_RS19615
uniprot id: A0A5P2EXL4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell membrane
messages: Probably interacts with PlsX.

223919:F3K33 RS08530
gene id: 223919:F3K33_RS08530
uniprot id: A0A5P2ESB3
names: Subcellular Location Annotation
messages: Membrane

223919:F3K33 RS20825
gene id: 223919:F3K33_RS20825
uniprot id: A0A5P2F184
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NRAMP family.
messages: Cell membrane
messages: H(+)-stimulated, divalent metal cation uptake system.

223919:F3K33 RS11530
gene id: 223919:F3K33_RS11530
uniprot id: A0A5P2EXR6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

223919:F3K33 RS03075
gene id: 223919:F3K33_RS03075
uniprot id: A0A5P2EPS5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

223919:F3K33 RS01885
gene id: 223919:F3K33_RS01885
uniprot id: A0A5P2EPB5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

223919:F3K33 RS19285
gene id: 223919:F3K33_RS19285
uniprot id: A0A5P2EXF6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 32 family.
messages: Cytoplasm
messages: Enables the bacterium to metabolize sucrose as a sole carbon source.

223919:F3K33 RS04100
gene id: 223919:F3K33_RS04100
uniprot id: A0A5P2F0Y2
names: Similarity
messages: Belongs to the TelA family.

223919:F3K33 RS24205
gene id: 223919:F3K33_RS24205
uniprot id: A0A5P2F067
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

223919:F3K33 RS04435
gene id: 223919:F3K33_RS04435
uniprot id: A0A5P2ETT2
names: Function
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.
messages: In the phosphorylated form it could act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma f from inhibition.

223919:F3K33 RS14935
gene id: 223919:F3K33_RS14935
uniprot id: A0A5P2EVE9
names: Subcellular Location Annotation
messages: Membrane

223919:F3K33 RS00800
gene id: 223919:F3K33_RS00800
uniprot id: A0A5P2EZ94
names: Similarity
messages: Belongs to the ycf81 family.

223919:F3K33 RS12465
gene id: 223919:F3K33_RS12465
uniprot id: A0A5P2EU94
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

223919:F3K33 RS18710
gene id: 223919:F3K33_RS18710
uniprot id: A0A5P2EXN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

223919:F3K33 RS02300
gene id: 223919:F3K33_RS02300
uniprot id: A0A5P2EPA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family.
messages: Membrane

223919:F3K33 RS05475
gene id: 223919:F3K33_RS05475
uniprot id: A0A5P2EQU0
names: Function
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.

223919:F3K33 RS19625
gene id: 223919:F3K33_RS19625
uniprot id: A0A5P2EXY0
names: Similarity
messages: Belongs to the YciI family.

223919:F3K33 RS05770
gene id: 223919:F3K33_RS05770
uniprot id: A0A5P2EWE6
names: Similarity
messages: Belongs to the UDPGP type 2 family.

223919:F3K33 RS25135
gene id: 223919:F3K33_RS25135
uniprot id: A0A5P2F700
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.

223919:F3K33 RS25035
gene id: 223919:F3K33_RS25035
uniprot id: A0A5P2F0S4
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

223919:F3K33 RS19485
gene id: 223919:F3K33_RS19485
uniprot id: A0A5P2F8W7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

223919:F3K33 RS00940
gene id: 223919:F3K33_RS00940
uniprot id: A0A5P2EQ99
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

223919:F3K33 RS05420
gene id: 223919:F3K33_RS05420
uniprot id: A0A5P2EQS5
names: Similarity
messages: Belongs to the asparagine synthetase family.

223919:F3K33 RS08150
gene id: 223919:F3K33_RS08150
uniprot id: A0A5P2ES81
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

223919:F3K33 RS05165
gene id: 223919:F3K33_RS05165
uniprot id: A0A5P2EQP8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

223919:F3K33 RS21950
gene id: 223919:F3K33_RS21950
uniprot id: A0A5P2F1H9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum
messages: Belongs to the FliD family.
messages: Homopentamer.
messages: Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
messages: Secreted

223919:F3K33 RS04400
gene id: 223919:F3K33_RS04400
uniprot id: A0A5P2EVM3
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

223919:F3K33 RS02900
gene id: 223919:F3K33_RS02900
uniprot id: A0A5P2F0A1
names: Similarity
messages: Belongs to the PspA/IM30 family.

223919:F3K33 RS21850
gene id: 223919:F3K33_RS21850
uniprot id: A0A5P2F1G3
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

223919:F3K33 RS15280
gene id: 223919:F3K33_RS15280
uniprot id: A0A5P2EYC9
names: Subcellular Location Annotation
messages: Membrane

223919:F3K33 RS04705
gene id: 223919:F3K33_RS04705
uniprot id: A0A5P2F191
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

223919:F3K33 RS00485
gene id: 223919:F3K33_RS00485
uniprot id: A0A5P2EQ23
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

223919:F3K33 RS22095
gene id: 223919:F3K33_RS22095
uniprot id: A0A5P2EZ82
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

223919:F3K33 RS11695
gene id: 223919:F3K33_RS11695
uniprot id: A0A5P2ETR3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

223919:F3K33 RS13930
gene id: 223919:F3K33_RS13930
uniprot id: A0A5P2EV16
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LamB/PxpA family.
messages: Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
messages: Forms a complex composed of PxpA, PxpB and PxpC.

223919:F3K33 RS12585
gene id: 223919:F3K33_RS12585
uniprot id: A0A5P2F5C8
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

223919:F3K33 RS20765
gene id: 223919:F3K33_RS20765
uniprot id: A0A5P2F9K1
names: Similarity
messages: Belongs to the bacterial microcompartments protein family.

223919:F3K33 RS13310
gene id: 223919:F3K33_RS13310
uniprot id: A0A5P2EY85
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

223919:F3K33 RS09435
gene id: 223919:F3K33_RS09435
uniprot id: A0A5P2F3Q1
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

223919:F3K33 RS22875
gene id: 223919:F3K33_RS22875
uniprot id: A0A5P2EZB9
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

223919:F3K33 RS06015
gene id: 223919:F3K33_RS06015
uniprot id: A0A5P2ER40
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family.
messages: Catalyzes the methylation of 5-hydroxyuridine (ho5U) to form 5-methoxyuridine (mo5U) at position 34 in tRNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

223919:F3K33 RS07375
gene id: 223919:F3K33_RS07375
uniprot id: A0A5P2F2M9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

223919:F3K33 RS18725
gene id: 223919:F3K33_RS18725
uniprot id: A0A5P2EZX7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

223919:F3K33 RS25185
gene id: 223919:F3K33_RS25185
uniprot id: A0A5P2F303
names: Similarity
messages: Belongs to the peptidase A8 family.

223919:F3K33 RS23315
gene id: 223919:F3K33_RS23315
uniprot id: A0A5P2F247
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reduced FMN (FMNH(2)).

223919:F3K33 RS06420
gene id: 223919:F3K33_RS06420
uniprot id: A0A5P2ERC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

223919:F3K33 RS23325
gene id: 223919:F3K33_RS23325
uniprot id: A0A5P2F435
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

223919:F3K33 RS26050
gene id: 223919:F3K33_RS26050
uniprot id: A0A5P2F155
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acyl-ACP thioesterase family.
messages: chloroplast

223919:F3K33 RS11000
gene id: 223919:F3K33_RS11000
uniprot id: A0A5P2EW81
names: Subcellular Location Annotation
messages: Membrane

223919:F3K33 RS07035
gene id: 223919:F3K33_RS07035
uniprot id: A0A5P2ERL4
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

223919:F3K33 RS03865
gene id: 223919:F3K33_RS03865
uniprot id: A0A5P2EQ55
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

223919:F3K33 RS20910
gene id: 223919:F3K33_RS20910
uniprot id: A0A5P2F0Y9
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

223919:F3K33 RS25350
gene id: 223919:F3K33_RS25350
uniprot id: A0A5P2F0J6
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

223919:F3K33 RS15595
gene id: 223919:F3K33_RS15595
uniprot id: A0A5P2EVR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

223919:F3K33 RS06530
gene id: 223919:F3K33_RS06530
uniprot id: A0A5P2ETI3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

223919:F3K33 RS15140
gene id: 223919:F3K33_RS15140
uniprot id: A0A5P2F1Q4
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

223919:F3K33 RS05340
gene id: 223919:F3K33_RS05340
uniprot id: A0A5P2F1K3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Cell membrane
messages: Membrane

223919:F3K33 RS11520
gene id: 223919:F3K33_RS11520
uniprot id: A0A5P2EWG5
names: Similarity
messages: Belongs to the organic radical-activating enzymes family.

223919:F3K33 RS06445
gene id: 223919:F3K33_RS06445
uniprot id: A0A5P2F264
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

223919:F3K33 RS21040
gene id: 223919:F3K33_RS21040
uniprot id: A0A5P2EYB6
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

223919:F3K33 RS06115
gene id: 223919:F3K33_RS06115
uniprot id: A0A5P2ER70
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

223919:F3K33 RS10020
gene id: 223919:F3K33_RS10020
uniprot id: A0A5P2EYS0
names: Similarity
messages: Belongs to the Ahb/Nir family.

223919:F3K33 RS02400
gene id: 223919:F3K33_RS02400
uniprot id: A0A5P2EPD1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

223919:F3K33 RS08920
gene id: 223919:F3K33_RS08920
uniprot id: A0A5P2EW03
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSP33 family.
messages: Cytoplasm
messages: Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.
messages: Under oxidizing conditions two disulfide bonds are formed involving the reactive cysteines. Under reducing conditions zinc is bound to the reactive cysteines and the protein is inactive.

223919:F3K33 RS21780
gene id: 223919:F3K33_RS21780
uniprot id: A0A5P2EYR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Membrane

223919:F3K33 RS15135
gene id: 223919:F3K33_RS15135
uniprot id: A0A5P2EY98
names: Subcellular Location Annotation
messages: Membrane

223919:F3K33 RS02825
gene id: 223919:F3K33_RS02825
uniprot id: A0A5P2ER82
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer and homodimer.

223919:F3K33 RS15825
gene id: 223919:F3K33_RS15825
uniprot id: A0A5P2F1F2
names: Subcellular Location Annotation
messages: Membrane

223919:F3K33 RS19055
gene id: 223919:F3K33_RS19055
uniprot id: A0A5P2F1R0
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

223919:F3K33 RS21485
gene id: 223919:F3K33_RS21485
uniprot id: A0A5P2F2B7
names: Cofactor
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

223919:F3K33 RS02335
gene id: 223919:F3K33_RS02335
uniprot id: A0A5P2ERN0
names: Similarity
messages: Belongs to the LacAB/RpiB family.

223919:F3K33 RS06680
gene id: 223919:F3K33_RS06680
uniprot id: A0A5P2ETL1
names: Cofactor
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

223919:F3K33 RS02965
gene id: 223919:F3K33_RS02965
uniprot id: A0A5P2EPF7
names: Similarity
messages: Belongs to the SfsA family.

223919:F3K33 RS06415
gene id: 223919:F3K33_RS06415
uniprot id: A0A5P2ER97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

223919:F3K33 RS03905
gene id: 223919:F3K33_RS03905
uniprot id: A0A5P2EPV8
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

223919:F3K33 RS04620
gene id: 223919:F3K33_RS04620
uniprot id: A0A5P2EQG2
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.

223919:F3K33 RS16615
gene id: 223919:F3K33_RS16615
uniprot id: A0A5P2F2K3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

223919:F3K33 RS18880
gene id: 223919:F3K33_RS18880
uniprot id: A0A5P2EXB6
names: Subcellular Location Annotation
messages: Membrane

223919:F3K33 RS26085
gene id: 223919:F3K33_RS26085
uniprot id: A0A5P2F0W7
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

223919:F3K33 RS04950
gene id: 223919:F3K33_RS04950
uniprot id: A0A5P2EQC9
names: Subcellular Location Annotation
messages: Membrane

223919:F3K33 RS03125
gene id: 223919:F3K33_RS03125
uniprot id: A0A5P2EPT3
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

223919:F3K33 RS00950
gene id: 223919:F3K33_RS00950
uniprot id: A0A5P2ES07
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

223919:F3K33 RS00650
gene id: 223919:F3K33_RS00650
uniprot id: A0A5P2EQ42
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of glycine to tRNA(Gly).
messages: Cytoplasm
messages: Homodimer.

223919:F3K33 RS05980
gene id: 223919:F3K33_RS05980
uniprot id: A0A5P2EUQ6
names: Similarity
messages: Belongs to the UPF0297 family.

223919:F3K33 RS02270
gene id: 223919:F3K33_RS02270
uniprot id: A0A5P2ESJ1
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

223919:F3K33 RS05620
gene id: 223919:F3K33_RS05620
uniprot id: A0A5P2EWB6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

223919:F3K33 RS21330
gene id: 223919:F3K33_RS21330
uniprot id: A0A5P2F305
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

223919:F3K33 RS10090
gene id: 223919:F3K33_RS10090
uniprot id: A0A5P2ET57
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAK/KUP transporter (TC 2.A.72) family.
messages: Cell membrane
messages: Membrane
messages: Transport of potassium into the cell.

223919:F3K33 RS25620
gene id: 223919:F3K33_RS25620
uniprot id: A0A5P2F790
names: Subcellular Location Annotation
messages: Membrane

223919:F3K33 RS25045
gene id: 223919:F3K33_RS25045
uniprot id: A0A5P2F2Y5
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

223919:F3K33 RS11955
gene id: 223919:F3K33_RS11955
uniprot id: A0A5P2ETZ9
names: Similarity
messages: Belongs to the UPF0047 family.

223919:F3K33 RS05855
gene id: 223919:F3K33_RS05855
uniprot id: A0A5P2ER14
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial solute-binding protein 2 family.
messages: Periplasm
messages: The ABC transporter complex is composed of one ATP-binding protein (MglA), two transmembrane proteins (MglC) and a solute-binding protein (MglB).

223919:F3K33 RS00910
gene id: 223919:F3K33_RS00910
uniprot id: A0A2P8RH15
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

223919:F3K33 RS16870
gene id: 223919:F3K33_RS16870
uniprot id: A0A5P2EZ28
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

223919:F3K33 RS10040
gene id: 223919:F3K33_RS10040
uniprot id: A0A5P2ET33
names: Similarity
messages: Belongs to the HepT RNase toxin family.

223919:F3K33 RS04485
gene id: 223919:F3K33_RS04485
uniprot id: A0A5P2ETU2
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Autoproteolytically processed. The inactive tetrameric zymogen termed p46 autoprocesses to a smaller form termed p41, which is active only during spore germination.
messages: Belongs to the peptidase A25 family.
messages: Homotetramer.
messages: Initiates the rapid degradation of small, acid-soluble proteins during spore germination.

223919:F3K33 RS22715
gene id: 223919:F3K33_RS22715
uniprot id: A0A5P2F279
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial solute-binding protein 2 family.
messages: Periplasm
messages: The ABC transporter complex is composed of one ATP-binding protein (MglA), two transmembrane proteins (MglC) and a solute-binding protein (MglB).

223919:F3K33 RS21175
gene id: 223919:F3K33_RS21175
uniprot id: A0A5P2F248
names: Similarity
messages: Belongs to the ArsC family.

223919:F3K33 RS19830
gene id: 223919:F3K33_RS19830
uniprot id: A0A5P2F239
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

223919:F3K33 RS21890
gene id: 223919:F3K33_RS21890
uniprot id: A0A5P2EZ49
names: Similarity
messages: Belongs to the polysaccharide synthase family.

223919:F3K33 RS20690
gene id: 223919:F3K33_RS20690
uniprot id: A0A5P2F7W9
names: Similarity
messages: Belongs to the bacterial microcompartments protein family.

223919:F3K33 RS15845
gene id: 223919:F3K33_RS15845
uniprot id: A0A5P2EW06
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/UDP phosphorylase family.
messages: Catalyzes the reversible phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
messages: Homohexamer; trimer of homodimers.

223919:F3K33 RS00035
gene id: 223919:F3K33_RS00035
uniprot id: A0A5P2ERL5
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

223919:F3K33 RS02520
gene id: 223919:F3K33_RS02520
uniprot id: A0A5P2ERR2
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

223919:F3K33 RS25115
gene id: 223919:F3K33_RS25115
uniprot id: A0A5P2F482
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sirtuin family. Class U subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form.

223919:F3K33 RS23320
gene id: 223919:F3K33_RS23320
uniprot id: A0A5P2F3A5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

223919:F3K33 RS12520
gene id: 223919:F3K33_RS12520
uniprot id: A0A5P2EWZ4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

223919:F3K33 RS23300
gene id: 223919:F3K33_RS23300
uniprot id: A0A5P2F044
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Monomer.

223919:F3K33 RS03085
gene id: 223919:F3K33_RS03085
uniprot id: A0A5P2ERC8
names: Similarity
messages: Belongs to the peptidase S11 family.

223919:F3K33 RS01020
gene id: 223919:F3K33_RS01020
uniprot id: A0A5P2ENH9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

223919:F3K33 RS09620
gene id: 223919:F3K33_RS09620
uniprot id: A0A5P2EYK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

223919:F3K33 RS02185
gene id: 223919:F3K33_RS02185
uniprot id: A0A5P2ERJ5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

223919:F3K33 RS13790
gene id: 223919:F3K33_RS13790
uniprot id: A0A5P2EXM4
names: Similarity
messages: Belongs to the TPP enzyme family.

223919:F3K33 RS25025
gene id: 223919:F3K33_RS25025
uniprot id: A0A5P2F0E8
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

223919:F3K33 RS20280
gene id: 223919:F3K33_RS20280
uniprot id: A0A5P2F1L9
names: Similarity
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.

223919:F3K33 RS10680
gene id: 223919:F3K33_RS10680
uniprot id: A0A5P2ETG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

223919:F3K33 RS11820
gene id: 223919:F3K33_RS11820
uniprot id: A0A5P2EXV2
names: Domain
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the CobB/CbiA family.
messages: Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source.
messages: Comprises of two domains. The C-terminal domain contains the binding site for glutamine and catalyzes the hydrolysis of this substrate to glutamate and ammonia. The N-terminal domain is anticipated to bind ATP and cobyrinate and catalyzes the ultimate synthesis of the diamide product. The ammonia produced via the glutaminase domain is probably translocated to the adjacent domain via a molecular tunnel, where it reacts with an activated intermediate.
messages: The a and c carboxylates of cobyrinate are activated for nucleophilic attack via formation of a phosphorylated intermediate by ATP. CbiA catalyzes first the amidation of the c-carboxylate, and then that of the a-carboxylate.

223919:F3K33 RS06335
gene id: 223919:F3K33_RS06335
uniprot id: A0A5P2EUP4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A probable RNA chaperone. Forms a complex with KhpB which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm
messages: Forms a complex with KhpB.

223919:F3K33 RS18265
gene id: 223919:F3K33_RS18265
uniprot id: A0A5P2EXE5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

223919:F3K33 RS18965
gene id: 223919:F3K33_RS18965
uniprot id: A0A5P2F3R1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane
messages: Part of an ABC transporter complex. Responsible for energy coupling to the transport system.

223919:F3K33 RS20505
gene id: 223919:F3K33_RS20505
uniprot id: A0A5P2EY19
names: Similarity
messages: Belongs to the KdgT transporter family.

223919:F3K33 RS12830
gene id: 223919:F3K33_RS12830
uniprot id: A0A5P2EUI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

223919:F3K33 RS08440
gene id: 223919:F3K33_RS08440
uniprot id: A0A5P2EVZ7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

223919:F3K33 RS25800
gene id: 223919:F3K33_RS25800
uniprot id: A0A5P2F150
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

223919:F3K33 RS07975
gene id: 223919:F3K33_RS07975
uniprot id: A0A5P2F2X4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

223919:F3K33 RS16945
gene id: 223919:F3K33_RS16945
uniprot id: A0A5P2F7I6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

223919:F3K33 RS16775
gene id: 223919:F3K33_RS16775
uniprot id: A0A5P2EZ42
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

223919:F3K33 RS07560
gene id: 223919:F3K33_RS07560
uniprot id: A0A5P2ERV8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpA family.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds the extracellular potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

223919:F3K33 RS24050
gene id: 223919:F3K33_RS24050
uniprot id: A0A5P2F3N6
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

223919:F3K33 RS16670
gene id: 223919:F3K33_RS16670
uniprot id: A0A5P2EW58
names: Subcellular Location Annotation
messages: Membrane

223919:F3K33 RS17610
gene id: 223919:F3K33_RS17610
uniprot id: A0A5P2F319
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

223919:F3K33 RS09655
gene id: 223919:F3K33_RS09655
uniprot id: A0A5P2EWQ5
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

223919:F3K33 RS22065
gene id: 223919:F3K33_RS22065
uniprot id: A0A5P2F3E9
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

223919:F3K33 RS07395
gene id: 223919:F3K33_RS07395
uniprot id: A0A5P2ERS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

223919:F3K33 RS09410
gene id: 223919:F3K33_RS09410
uniprot id: A0A5P2ESV2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.
messages: Ca(+)/H(+) antiporter that extrudes calcium in exchange for external protons.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

223919:F3K33 RS09995
gene id: 223919:F3K33_RS09995
uniprot id: A0A5P2EVM7
names: Function
names: Similarity
messages: Belongs to the NifD/NifK/NifE/NifN family.
messages: Belongs to the radical SAM superfamily. NifB family.
messages: Involved in the biosynthesis of the iron-molybdenum cofactor (FeMo-co or M-cluster) found in the dinitrogenase enzyme of the nitrogenase complex in nitrogen-fixing microorganisms. NifB catalyzes the crucial step of radical SAM-dependent carbide insertion that occurs concomitant with the insertion of a 9th sulfur and the rearrangement/coupling of two [4Fe-4S] clusters into a [8Fe-9S-C] cluster, the precursor to the M-cluster.

223919:F3K33 RS08220
gene id: 223919:F3K33_RS08220
uniprot id: A0A5P2EVN5
names: Similarity
messages: Belongs to the UPF0749 family.

223919:F3K33 RS18370
gene id: 223919:F3K33_RS18370
uniprot id: A0A5P2F3F0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

223919:F3K33 RS00610
gene id: 223919:F3K33_RS00610
uniprot id: A0A5P2ETQ1
names: Similarity
messages: Belongs to the formate--tetrahydrofolate ligase family.

223919:F3K33 RS11025
gene id: 223919:F3K33_RS11025
uniprot id: A0A5P2EZC8
names: Function
names: Similarity
messages: Belongs to the mannonate dehydratase family.
messages: Catalyzes the dehydration of D-mannonate.

223919:F3K33 RS03385
gene id: 223919:F3K33_RS03385
uniprot id: A0A5P2EPM6
names: Similarity
messages: Belongs to the glycosyl hydrolase 25 family.

223919:F3K33 RS13160
gene id: 223919:F3K33_RS13160
uniprot id: A0A5P2EY56
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

223919:F3K33 RS12540
gene id: 223919:F3K33_RS12540
uniprot id: A0A5P2EWX8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

223919:F3K33 RS02390
gene id: 223919:F3K33_RS02390
uniprot id: A0A5P2EUL0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

223919:F3K33 RS05985
gene id: 223919:F3K33_RS05985
uniprot id: A0A5P2F1X2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

223919:F3K33 RS08585
gene id: 223919:F3K33_RS08585
uniprot id: A0A5P2EUN1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

223919:F3K33 RS23645
gene id: 223919:F3K33_RS23645
uniprot id: A0A5P2F491
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 3B subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

223919:F3K33 RS17365
gene id: 223919:F3K33_RS17365
uniprot id: A0A5P2EWG1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial solute-binding protein 2 family.
messages: Periplasm
messages: The ABC transporter complex is composed of one ATP-binding protein (MglA), two transmembrane proteins (MglC) and a solute-binding protein (MglB).

223919:F3K33 RS14450
gene id: 223919:F3K33_RS14450
uniprot id: A0A5P2EVB0
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

223919:F3K33 RS05170
gene id: 223919:F3K33_RS05170
uniprot id: A0A5P2EQN6
names: Similarity
messages: Belongs to the phosphohexose mutase family.

223919:F3K33 RS09040
gene id: 223919:F3K33_RS09040
uniprot id: A0A5P2EY95
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

223919:F3K33 RS12815
gene id: 223919:F3K33_RS12815
uniprot id: A0A5P2F0B4
names: Function
names: Similarity
messages: Belongs to the SELO family.
messages: Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).

223919:F3K33 RS23350
gene id: 223919:F3K33_RS23350
uniprot id: A0A5P2F053
names: Function
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. NagD family.
messages: Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro.

223919:F3K33 RS02955
gene id: 223919:F3K33_RS02955
uniprot id: A0A5P2ERY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Membrane

223919:F3K33 RS04710
gene id: 223919:F3K33_RS04710
uniprot id: A0A5P2ESW1
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

223919:F3K33 RS11635
gene id: 223919:F3K33_RS11635
uniprot id: A0A5P2ETX2
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

223919:F3K33 RS15755
gene id: 223919:F3K33_RS15755
uniprot id: A0A5P2EYL1
names: Subcellular Location Annotation
messages: Membrane

223919:F3K33 RS24615
gene id: 223919:F3K33_RS24615
uniprot id: A0A5P2F0V0
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

223919:F3K33 RS09525
gene id: 223919:F3K33_RS09525
uniprot id: A0A5P2ESV3
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily.

223919:F3K33 RS06645
gene id: 223919:F3K33_RS06645
uniprot id: A0A5P2F2A0
names: Subcellular Location Annotation
messages: Membrane

223919:F3K33 RS20510
gene id: 223919:F3K33_RS20510
uniprot id: A0A5P2EYK9
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

223919:F3K33 RS12195
gene id: 223919:F3K33_RS12195
uniprot id: A0A5P2EZY3
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Catalyzes the phosphorylation of D-xylulose to D-xylulose 5-phosphate.

223919:F3K33 RS15875
gene id: 223919:F3K33_RS15875
uniprot id: A0A5P2EYP7
names: Function
messages: TetR is the repressor of the tetracycline resistance element; its N-terminal region forms a helix-turn-helix structure and binds DNA. Binding of tetracycline to TetR reduces the repressor affinity for the tetracycline resistance gene (tetA) promoter operator sites.

223919:F3K33 RS25295
gene id: 223919:F3K33_RS25295
uniprot id: A0A5P2F721
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

223919:F3K33 RS13365
gene id: 223919:F3K33_RS13365
uniprot id: A0A5P2EYM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Membrane

223919:F3K33 RS07985
gene id: 223919:F3K33_RS07985
uniprot id: A0A5P2EXP2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

223919:F3K33 RS02310
gene id: 223919:F3K33_RS02310
uniprot id: A0A5P2EP38
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.

223919:F3K33 RS04010
gene id: 223919:F3K33_RS04010
uniprot id: A0A5P2EPX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

223919:F3K33 RS10240
gene id: 223919:F3K33_RS10240
uniprot id: A0A5P2EVS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

223919:F3K33 RS00930
gene id: 223919:F3K33_RS00930
uniprot id: A0A5P2ENW8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

223919:F3K33 RS02150
gene id: 223919:F3K33_RS02150
uniprot id: A0A5P2EP83
names: Similarity
messages: Belongs to the peptidase U62 family.

223919:F3K33 RS11415
gene id: 223919:F3K33_RS11415
uniprot id: A0A5P2F4T3
names: Similarity
messages: Belongs to the UPF0166 family.

223919:F3K33 RS19675
gene id: 223919:F3K33_RS19675
uniprot id: A0A5P2F197
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family.
messages: Cell membrane
messages: Membrane

223919:F3K33 RS09265
gene id: 223919:F3K33_RS09265
uniprot id: A0A5P2EV86
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

223919:F3K33 RS10675
gene id: 223919:F3K33_RS10675
uniprot id: A0A5P2ETF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

223919:F3K33 RS14885
gene id: 223919:F3K33_RS14885
uniprot id: A0A5P2F6I8
names: Subcellular Location Annotation
messages: Cytoplasm

223919:F3K33 RS03440
gene id: 223919:F3K33_RS03440
uniprot id: A0A5P2ERI8
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

223919:F3K33 RS03915
gene id: 223919:F3K33_RS03915
uniprot id: A0A5P2EQ60
names: Subcellular Location Annotation
messages: Membrane

223919:F3K33 RS14730
gene id: 223919:F3K33_RS14730
uniprot id: A0A5P2EY42
names: Subcellular Location Annotation
messages: Membrane

223919:F3K33 RS24650
gene id: 223919:F3K33_RS24650
uniprot id: A0A5P2F3D0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Membrane

223919:F3K33 RS06215
gene id: 223919:F3K33_RS06215
uniprot id: A0A5P2ER62
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

223919:F3K33 RS12605
gene id: 223919:F3K33_RS12605
uniprot id: A0A5P2EUD3
names: Similarity
messages: Belongs to the FBPase class 3 family.

223919:F3K33 RS08255
gene id: 223919:F3K33_RS08255
uniprot id: A0A5P2ES99
names: Subcellular Location Annotation
messages: Cytoplasm

223919:F3K33 RS20285
gene id: 223919:F3K33_RS20285
uniprot id: A0A5P2F2B2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SspH family.
messages: Spore core

223919:F3K33 RS02770
gene id: 223919:F3K33_RS02770
uniprot id: A0A5P2EPB8
names: Similarity
messages: Belongs to the xanthine dehydrogenase family.

223919:F3K33 RS01635
gene id: 223919:F3K33_RS01635
uniprot id: A0A5P2ESD5
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

223919:F3K33 RS00875
gene id: 223919:F3K33_RS00875
uniprot id: A0A5P2ENP5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

223919:F3K33 RS06175
gene id: 223919:F3K33_RS06175
uniprot id: A0A5P2ER68
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

223919:F3K33 RS03185
gene id: 223919:F3K33_RS03185
uniprot id: A0A5P2ERE2
names: Similarity
messages: Belongs to the aldolase class II family. AraD/FucA subfamily.

223919:F3K33 RS05640
gene id: 223919:F3K33_RS05640
uniprot id: A0A5P2EQY0
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

223919:F3K33 RS15720
gene id: 223919:F3K33_RS15720
uniprot id: A0A5P2F6X8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

223919:F3K33 RS13675
gene id: 223919:F3K33_RS13675
uniprot id: A0A5P2EUZ1
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

223919:F3K33 RS19380
gene id: 223919:F3K33_RS19380
uniprot id: A0A5P2F0G7
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MobA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.
messages: Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.

223919:F3K33 RS16460
gene id: 223919:F3K33_RS16460
uniprot id: A0A5P2EYX8
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

223919:F3K33 RS10565
gene id: 223919:F3K33_RS10565
uniprot id: A0A5P2ETD8
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

223919:F3K33 RS16880
gene id: 223919:F3K33_RS16880
uniprot id: A0A5P2F0R0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

223919:F3K33 RS07200
gene id: 223919:F3K33_RS07200
uniprot id: A0A5P2EV56
names: Subcellular Location Annotation
messages: Membrane

223919:F3K33 RS12825
gene id: 223919:F3K33_RS12825
uniprot id: A0A5P2EUG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

223919:F3K33 RS10060
gene id: 223919:F3K33_RS10060
uniprot id: A0A5P2F426
names: Similarity
messages: Belongs to the HicA mRNA interferase family.

223919:F3K33 RS20980
gene id: 223919:F3K33_RS20980
uniprot id: A0A5P2F1B4
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

223919:F3K33 RS12205
gene id: 223919:F3K33_RS12205
uniprot id: A0A5P2EU60
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 3B subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

223919:F3K33 RS04365
gene id: 223919:F3K33_RS04365
uniprot id: A0A5P2EQ70
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.

223919:F3K33 RS16415
gene id: 223919:F3K33_RS16415
uniprot id: A0A5P2F7B2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

223919:F3K33 RS12885
gene id: 223919:F3K33_RS12885
uniprot id: A0A5P2EUJ7
names: Similarity
messages: Belongs to the class II ribonucleoside-triphosphate reductase family.

223919:F3K33 RS21795
gene id: 223919:F3K33_RS21795
uniprot id: A0A5P2EYV0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

223919:F3K33 RS16320
gene id: 223919:F3K33_RS16320
uniprot id: A0A5P2F2F3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-C family. PolC subfamily.
messages: Cytoplasm
messages: Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

223919:F3K33 RS20725
gene id: 223919:F3K33_RS20725
uniprot id: A0A5P2EY61
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

223919:F3K33 RS23310
gene id: 223919:F3K33_RS23310
uniprot id: A0A5P2EZQ2
names: Function
names: Subcellular Location Annotation
messages: Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.
messages: Cytoplasm

223919:F3K33 RS25075
gene id: 223919:F3K33_RS25075
uniprot id: A0A5P2F0F8
names: Similarity
messages: Belongs to the peptidase C40 family.

223919:F3K33 RS10195
gene id: 223919:F3K33_RS10195
uniprot id: A0A5P2ET01
names: Subcellular Location Annotation
messages: Membrane

223919:F3K33 RS22075
gene id: 223919:F3K33_RS22075
uniprot id: A0A5P2F1W7
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

223919:F3K33 RS13655
gene id: 223919:F3K33_RS13655
uniprot id: A0A5P2EXI7
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane.

223919:F3K33 RS03760
gene id: 223919:F3K33_RS03760
uniprot id: A0A5P2ERQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

223919:F3K33 RS25785
gene id: 223919:F3K33_RS25785
uniprot id: A0A5P2F7B8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

223919:F3K33 RS25685
gene id: 223919:F3K33_RS25685
uniprot id: A0A5P2F134
names: Subcellular Location Annotation
messages: Membrane

223919:F3K33 RS09990
gene id: 223919:F3K33_RS09990
uniprot id: A0A5P2ET24
names: Function
names: Similarity
messages: Belongs to the NifD/NifK/NifE/NifN family.
messages: This protein may play a role in the biosynthesis of the prosthetic group of nitrogenase (FeMo cofactor).

223919:F3K33 RS22670
gene id: 223919:F3K33_RS22670
uniprot id: A0A5P2EZ79
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.

223919:F3K33 RS20580
gene id: 223919:F3K33_RS20580
uniprot id: A0A5P2F0S6
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

223919:F3K33 RS05760
gene id: 223919:F3K33_RS05760
uniprot id: A0A5P2F1T6
names: Similarity
messages: Belongs to the UDP-galactopyranose/dTDP-fucopyranose mutase family.

223919:F3K33 RS05255
gene id: 223919:F3K33_RS05255
uniprot id: A0A5P2EQH5
names: Function
names: Similarity
messages: Belongs to the PyrI family.
messages: Involved in allosteric regulation of aspartate carbamoyltransferase.

223919:F3K33 RS06380
gene id: 223919:F3K33_RS06380
uniprot id: A0A5P2ETE9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

223919:F3K33 RS13770
gene id: 223919:F3K33_RS13770
uniprot id: A0A5P2EUT6
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

223919:F3K33 RS22680
gene id: 223919:F3K33_RS22680
uniprot id: A0A5P2EZI4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial solute-binding protein 2 family.
messages: Periplasm
messages: The ABC transporter complex is composed of one ATP-binding protein (MglA), two transmembrane proteins (MglC) and a solute-binding protein (MglB).

223919:F3K33 RS24170
gene id: 223919:F3K33_RS24170
uniprot id: A0A5P2F331
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

223919:F3K33 RS22645
gene id: 223919:F3K33_RS22645
uniprot id: A0A5P2F2Y1
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

223919:F3K33 RS20425
gene id: 223919:F3K33_RS20425
uniprot id: A0A5P2F0P9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Cell membrane
messages: Membrane

223919:F3K33 RS09930
gene id: 223919:F3K33_RS09930
uniprot id: A0A5P2ET28
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

223919:F3K33 RS06605
gene id: 223919:F3K33_RS06605
uniprot id: A0A5P2EWX7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

223919:F3K33 RS04565
gene id: 223919:F3K33_RS04565
uniprot id: A0A5P2EQD1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

223919:F3K33 RS06195
gene id: 223919:F3K33_RS06195
uniprot id: A0A5P2F211
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

223919:F3K33 RS09035
gene id: 223919:F3K33_RS09035
uniprot id: A0A5P2EV60
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. DbpA subfamily.
messages: Contains an N-terminal domain that binds non-specifically to RNA and a C-terminal domain that binds specifically and tightly to hairpin 92 of 23S rRNA.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes.

223919:F3K33 RS08675
gene id: 223919:F3K33_RS08675
uniprot id: A0A5P2ESE7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

223919:F3K33 RS21975
gene id: 223919:F3K33_RS21975
uniprot id: A0A5P2F5D0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin. Binds to flagellin and participates in the assembly of the flagellum.
messages: Belongs to the FliW family.
messages: Cytoplasm
messages: Interacts with translational regulator CsrA and flagellin(s).

223919:F3K33 RS23590
gene id: 223919:F3K33_RS23590
uniprot id: A0A5P2F3F5
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane.

223919:F3K33 RS25765
gene id: 223919:F3K33_RS25765
uniprot id: A0A5P2F4I9
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

223919:F3K33 RS14325
gene id: 223919:F3K33_RS14325
uniprot id: A0A5P2EXX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

223919:F3K33 RS18960
gene id: 223919:F3K33_RS18960
uniprot id: A0A5P2F088
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CbiM family.
messages: Cell membrane
messages: Forms an energy-coupling factor (ECF) transporter complex composed of an ATP-binding protein (A component, CbiO), a transmembrane protein (T component, CbiQ) and 2 possible substrate-capture proteins (S components, CbiM and CbiN) of unknown stoichimetry.
messages: Membrane
messages: Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import.

223919:F3K33 RS19630
gene id: 223919:F3K33_RS19630
uniprot id: A0A5P2EXQ4
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

223919:F3K33 RS10220
gene id: 223919:F3K33_RS10220
uniprot id: A0A5P2EWN7
names: Cofactor
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Binds 1 FAD per subunit.
messages: Binds 1 FMN covalently per subunit.

223919:F3K33 RS12385
gene id: 223919:F3K33_RS12385
uniprot id: A0A5P2F589
names: Similarity
messages: Belongs to the peptidase S66 family.

223919:F3K33 RS24465
gene id: 223919:F3K33_RS24465
uniprot id: A0A5P2F0B6
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

223919:F3K33 RS10115
gene id: 223919:F3K33_RS10115
uniprot id: A0A5P2EWL8
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

223919:F3K33 RS09085
gene id: 223919:F3K33_RS09085
uniprot id: A0A5P2EV68
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Uronate isomerase family.

223919:F3K33 RS16560
gene id: 223919:F3K33_RS16560
uniprot id: A0A5P2EWL7
names: Function
names: Similarity
messages: Belongs to the alpha/beta-type SASP family.
messages: SASP are bound to spore DNA. They are double-stranded DNA-binding proteins that cause DNA to change to an a-like conformation. They protect the DNA backbone from chemical and enzymatic cleavage and are thus involved in dormant spore's high resistance to UV light.

223919:F3K33 RS12695
gene id: 223919:F3K33_RS12695
uniprot id: A0A5P2F089
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

223919:F3K33 RS19450
gene id: 223919:F3K33_RS19450
uniprot id: A0A5P2EXV1
names: Cofactor
messages: Binds 1 Mg(2+) ion per trimer.

223919:F3K33 RS15320
gene id: 223919:F3K33_RS15320
uniprot id: A0A5P2EVW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NlpA lipoprotein family.
messages: Membrane

223919:F3K33 RS03620
gene id: 223919:F3K33_RS03620
uniprot id: A0A5P2ESB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nlpA lipoprotein family.
messages: Membrane

223919:F3K33 RS22015
gene id: 223919:F3K33_RS22015
uniprot id: A0A5P2F3D7
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: Membrane