2213200:BOX37 RS04395
gene id: 2213200:BOX37_RS04395
uniprot id: A0A1J0VMS0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

2213200:BOX37 RS21410
gene id: 2213200:BOX37_RS21410
uniprot id: A0A1J0VVH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

2213200:BOX37 RS22140
gene id: 2213200:BOX37_RS22140
uniprot id: A0A1J0VVP6
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

2213200:BOX37 RS06180
gene id: 2213200:BOX37_RS06180
uniprot id: A0A1J0VNJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

2213200:BOX37 RS30495
gene id: 2213200:BOX37_RS30495
uniprot id: A0A1J0VZM2
names: Similarity
messages: Belongs to the AB hydrolase superfamily. Lipase family.

2213200:BOX37 RS25975
gene id: 2213200:BOX37_RS25975
uniprot id: A0A1J0VXL1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

2213200:BOX37 RS11295
gene id: 2213200:BOX37_RS11295
uniprot id: A0A1J0VQY3
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

2213200:BOX37 RS19005
gene id: 2213200:BOX37_RS19005
uniprot id: A0A1J0VUH4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Cytoplasm
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the insertion of ferrous iron into coproporphyrin III to form Fe-coproporphyrin III.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2213200:BOX37 RS06705
gene id: 2213200:BOX37_RS06705
uniprot id: A0A1J0VNT2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

2213200:BOX37 RS31300
gene id: 2213200:BOX37_RS31300
uniprot id: A0A1J0VZV0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

2213200:BOX37 RS31135
gene id: 2213200:BOX37_RS31135
uniprot id: A0A1J0VZW1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the F420-dependent glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the coenzyme F420-dependent oxidation of glucose 6-phosphate (G6P) to 6-phosphogluconolactone.
messages: Homodimer.

2213200:BOX37 RS22505
gene id: 2213200:BOX37_RS22505
uniprot id: A0A1J0VVY2
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. S-2-haloalkanoic acid dehalogenase family.

2213200:BOX37 RS18190
gene id: 2213200:BOX37_RS18190
uniprot id: A0A1J0VTZ5
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

2213200:BOX37 RS29850
gene id: 2213200:BOX37_RS29850
uniprot id: A0A1J0VZD2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

2213200:BOX37 RS04185
gene id: 2213200:BOX37_RS04185
uniprot id: A0A1J0VMM5
names: Similarity
messages: Belongs to the EccE family.

2213200:BOX37 RS30020
gene id: 2213200:BOX37_RS30020
uniprot id: A0A1J0VZF1
names: Subcellular Location Annotation
messages: Membrane

2213200:BOX37 RS13075
gene id: 2213200:BOX37_RS13075
uniprot id: A0A1J0VRR8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

2213200:BOX37 RS25010
gene id: 2213200:BOX37_RS25010
uniprot id: A0A1J0VXC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acid desaturase type 1 family. AlkB subfamily.
messages: Cell inner membrane
messages: Membrane

2213200:BOX37 RS04310
gene id: 2213200:BOX37_RS04310
uniprot id: A0A1J0VMP8
names: Subcellular Location Annotation
messages: Membrane

2213200:BOX37 RS11625
gene id: 2213200:BOX37_RS11625
uniprot id: A0A1J0VR29
names: Similarity
messages: Belongs to the Nudix hydrolase family.

2213200:BOX37 RS22545
gene id: 2213200:BOX37_RS22545
uniprot id: A0A1J0W2T6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2213200:BOX37 RS04960
gene id: 2213200:BOX37_RS04960
uniprot id: A0A1J0VN12
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

2213200:BOX37 RS25630
gene id: 2213200:BOX37_RS25630
uniprot id: A0A1J0VX71
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

2213200:BOX37 RS20920
gene id: 2213200:BOX37_RS20920
uniprot id: A0A1J0VVC2
names: Subcellular Location Annotation
messages: Membrane

2213200:BOX37 RS25020
gene id: 2213200:BOX37_RS25020
uniprot id: A0A1J0VX44
names: Cofactor
names: Function
names: Similarity
messages: Bifunctional enzyme that catalyzes the GTP-dependent successive addition of two or more gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives, and the FMNH2-dependent reduction of dehydro-F420-0 to form F420-0.
messages: Binds 2 divalent metal cations per subunit. The ions could be magnesium and/or manganese.
messages: In the N-terminal section; belongs to the CofE family.
messages: Monovalent cation. The ion could be potassium.

2213200:BOX37 RS17070
gene id: 2213200:BOX37_RS17070
uniprot id: A0A1J0VTH8
names: Subunit
messages: Heterodimer of an alpha and a beta chain.

2213200:BOX37 RS21325
gene id: 2213200:BOX37_RS21325
uniprot id: A0A1J0VVF1
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

2213200:BOX37 RS30645
gene id: 2213200:BOX37_RS30645
uniprot id: A0A1J0VZX0
names: Similarity
messages: Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family.

2213200:BOX37 RS23635
gene id: 2213200:BOX37_RS23635
uniprot id: A0A1J0VWF0
names: Similarity
messages: Belongs to the cytochrome P450 family.

2213200:BOX37 RS06420
gene id: 2213200:BOX37_RS06420
uniprot id: A0A1J0VNN2
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

2213200:BOX37 RS07035
gene id: 2213200:BOX37_RS07035
uniprot id: A0A1J0VP07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic sulfate-binding protein family.
messages: Periplasm

2213200:BOX37 RS01955
gene id: 2213200:BOX37_RS01955
uniprot id: A0A1J0VLM5
names: Similarity
messages: Belongs to the AHA1 family.

2213200:BOX37 RS31420
gene id: 2213200:BOX37_RS31420
uniprot id: A0A1J0W022
names: Similarity
messages: Belongs to the EspG family.

2213200:BOX37 RS08225
gene id: 2213200:BOX37_RS08225
uniprot id: A0A1J0VPH6
names: Caution
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2213200:BOX37 RS26830
gene id: 2213200:BOX37_RS26830
uniprot id: A0A1J0VXU2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2213200:BOX37 RS14905
gene id: 2213200:BOX37_RS14905
uniprot id: A0A1J0VSH9
names: Similarity
messages: Belongs to the AB hydrolase superfamily. Lipase family.

2213200:BOX37 RS25045
gene id: 2213200:BOX37_RS25045
uniprot id: A0A1J0VX57
names: Similarity
messages: Belongs to the phosphohexose mutase family.

2213200:BOX37 RS21810
gene id: 2213200:BOX37_RS21810
uniprot id: A0A1J0VVM6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

2213200:BOX37 RS25060
gene id: 2213200:BOX37_RS25060
uniprot id: A0A1J0VXD2
names: Subcellular Location Annotation
messages: Membrane

2213200:BOX37 RS19990
gene id: 2213200:BOX37_RS19990
uniprot id: A0A1J0VV36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

2213200:BOX37 RS29335
gene id: 2213200:BOX37_RS29335
uniprot id: A0A1J0VZ56
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2213200:BOX37 RS03945
gene id: 2213200:BOX37_RS03945
uniprot id: A0A1J0VML5
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

2213200:BOX37 RS11855
gene id: 2213200:BOX37_RS11855
uniprot id: A0A1J0VR41
names: Similarity
messages: Belongs to the 4-hydroxy-2-oxovalerate aldolase family.

2213200:BOX37 RS01175
gene id: 2213200:BOX37_RS01175
uniprot id: A0A1J0VLC8
names: Subcellular Location Annotation
messages: Membrane

2213200:BOX37 RS15395
gene id: 2213200:BOX37_RS15395
uniprot id: A0A1J0VSR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2213200:BOX37 RS29575
gene id: 2213200:BOX37_RS29575
uniprot id: A0A1J0VYY5
names: Similarity
messages: Belongs to the F420H(2)-dependent quinone reductase family.

2213200:BOX37 RS21135
gene id: 2213200:BOX37_RS21135
uniprot id: A0A1J0VV80
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

2213200:BOX37 RS04290
gene id: 2213200:BOX37_RS04290
uniprot id: A0A1J0VMT4
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

2213200:BOX37 RS20955
gene id: 2213200:BOX37_RS20955
uniprot id: A0A1J0W2R1
names: Subcellular Location Annotation
messages: Cytoplasm

2213200:BOX37 RS00860
gene id: 2213200:BOX37_RS00860
uniprot id: A0A1J0VL43
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 85 family.
messages: Cell membrane
messages: Membrane

2213200:BOX37 RS11690
gene id: 2213200:BOX37_RS11690
uniprot id: A0A1J0VR20
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

2213200:BOX37 RS04030
gene id: 2213200:BOX37_RS04030
uniprot id: A0A1J0VML1
names: Similarity
messages: Belongs to the mycobacterial PPE family.

2213200:BOX37 RS04115
gene id: 2213200:BOX37_RS04115
uniprot id: A0A1J0VMQ1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

2213200:BOX37 RS10290
gene id: 2213200:BOX37_RS10290
uniprot id: A0A1J0VQE6
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

2213200:BOX37 RS15245
gene id: 2213200:BOX37_RS15245
uniprot id: A0A1J0W222
names: Similarity
messages: Belongs to the gluconokinase GntK/GntV family.

2213200:BOX37 RS27825
gene id: 2213200:BOX37_RS27825
uniprot id: A0A1J0VYF7
names: Similarity
messages: Belongs to the cytochrome P450 family.

2213200:BOX37 RS30510
gene id: 2213200:BOX37_RS30510
uniprot id: A0A1J0VZC7
names: Similarity
messages: Belongs to the WXG100 family.

2213200:BOX37 RS09005
gene id: 2213200:BOX37_RS09005
uniprot id: A0A1J0VQ32
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2213200:BOX37 RS12495
gene id: 2213200:BOX37_RS12495
uniprot id: A0A1J0VRE6
names: Similarity
messages: Belongs to the FAD-binding monooxygenase family.

2213200:BOX37 RS08085
gene id: 2213200:BOX37_RS08085
uniprot id: A0A1J0W1Q2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

2213200:BOX37 RS10090
gene id: 2213200:BOX37_RS10090
uniprot id: A0A1J0VQC8
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

2213200:BOX37 RS05045
gene id: 2213200:BOX37_RS05045
uniprot id: A0A1J0W145
names: Similarity
messages: Belongs to the F420H(2)-dependent quinone reductase family.

2213200:BOX37 RS30920
gene id: 2213200:BOX37_RS30920
uniprot id: A0A1J0VZT9
names: Similarity
messages: Belongs to the homogentisate dioxygenase family.

2213200:BOX37 RS27540
gene id: 2213200:BOX37_RS27540
uniprot id: A0A1J0W395
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

2213200:BOX37 RS27800
gene id: 2213200:BOX37_RS27800
uniprot id: A0A1J0VYE5
names: Similarity
messages: Belongs to the universal stress protein A family.

2213200:BOX37 RS05880
gene id: 2213200:BOX37_RS05880
uniprot id: A0A1J0VNH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2213200:BOX37 RS17680
gene id: 2213200:BOX37_RS17680
uniprot id: A0A1J0VTU9
names: Subcellular Location Annotation
messages: Cytoplasm

2213200:BOX37 RS15875
gene id: 2213200:BOX37_RS15875
uniprot id: A0A1J0VT06
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane

2213200:BOX37 RS11565
gene id: 2213200:BOX37_RS11565
uniprot id: A0A1J0W1N6
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

2213200:BOX37 RS09025
gene id: 2213200:BOX37_RS09025
uniprot id: A0A1J0W1K8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Rieske iron-sulfur protein family.
messages: Cell membrane
messages: Iron-sulfur subunit of the cytochrome bc1 complex, an essential component of the respiratory electron transport chain required for ATP synthesis. The bc1 complex catalyzes the oxidation of menaquinol and the reduction of cytochrome c in the respiratory chain. The bc1 complex operates through a Q-cycle mechanism that couples electron transfer to generation of the proton gradient that drives ATP synthesis.
messages: Membrane

2213200:BOX37 RS23630
gene id: 2213200:BOX37_RS23630
uniprot id: A0A1J0VWD2
names: Similarity
messages: Belongs to the cytochrome P450 family.

2213200:BOX37 RS26505
gene id: 2213200:BOX37_RS26505
uniprot id: A0A1J0VXU3
names: Similarity
messages: Belongs to the YciI family.

2213200:BOX37 RS21010
gene id: 2213200:BOX37_RS21010
uniprot id: A0A1J0VVI8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

2213200:BOX37 RS07220
gene id: 2213200:BOX37_RS07220
uniprot id: A0A1J0VP39
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

2213200:BOX37 RS29095
gene id: 2213200:BOX37_RS29095
uniprot id: A0A1J0VYU3
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

2213200:BOX37 RS29150
gene id: 2213200:BOX37_RS29150
uniprot id: A0A1J0W3E3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

2213200:BOX37 RS09075
gene id: 2213200:BOX37_RS09075
uniprot id: A0A1J0VQ37
names: Similarity
messages: Belongs to the carotenoid/retinoid oxidoreductase family.

2213200:BOX37 RS03725
gene id: 2213200:BOX37_RS03725
uniprot id: A0A1J0VMI4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

2213200:BOX37 RS11340
gene id: 2213200:BOX37_RS11340
uniprot id: A0A1J0VR51
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

2213200:BOX37 RS09565
gene id: 2213200:BOX37_RS09565
uniprot id: A0A1J0VQ34
names: Similarity
messages: Belongs to the arylamine N-acetyltransferase family.

2213200:BOX37 RS32790
gene id: 2213200:BOX37_RS32790
uniprot id: A0A1J0W0N7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

2213200:BOX37 RS25625
gene id: 2213200:BOX37_RS25625
uniprot id: A0A1J0VXM2
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

2213200:BOX37 RS09995
gene id: 2213200:BOX37_RS09995
uniprot id: A0A1J0W1Q0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

2213200:BOX37 RS01730
gene id: 2213200:BOX37_RS01730
uniprot id: A0A1J0VLK5
names: Similarity
messages: Belongs to the YoeB family.

2213200:BOX37 RS19870
gene id: 2213200:BOX37_RS19870
uniprot id: A0A1J0VUU1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

2213200:BOX37 RS22585
gene id: 2213200:BOX37_RS22585
uniprot id: A0A1J0VW20
names: Subcellular Location Annotation
messages: Membrane

2213200:BOX37 RS12735
gene id: 2213200:BOX37_RS12735
uniprot id: A0A1J0VRH9
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

2213200:BOX37 RS32335
gene id: 2213200:BOX37_RS32335
uniprot id: A0A1J0W0M4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

2213200:BOX37 RS17965
gene id: 2213200:BOX37_RS17965
uniprot id: A0A1J0VTV2
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

2213200:BOX37 RS00655
gene id: 2213200:BOX37_RS00655
uniprot id: A0A1J0VL47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

2213200:BOX37 RS29955
gene id: 2213200:BOX37_RS29955
uniprot id: A0A1J0VZ80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

2213200:BOX37 RS10370
gene id: 2213200:BOX37_RS10370
uniprot id: A0A1J0VQF4
names: Subcellular Location Annotation
messages: Membrane

2213200:BOX37 RS24105
gene id: 2213200:BOX37_RS24105
uniprot id: A0A1J0VWP9
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF2.
messages: Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.

2213200:BOX37 RS19490
gene id: 2213200:BOX37_RS19490
uniprot id: A0A1J0VUW8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

2213200:BOX37 RS08915
gene id: 2213200:BOX37_RS08915
uniprot id: A0A1J0W1D6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Membrane
messages: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).

2213200:BOX37 RS01435
gene id: 2213200:BOX37_RS01435
uniprot id: A0A1J0VLD9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2213200:BOX37 RS30440
gene id: 2213200:BOX37_RS30440
uniprot id: A0A1J0VZE4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

2213200:BOX37 RS00710
gene id: 2213200:BOX37_RS00710
uniprot id: A0A1J0VL32
names: Similarity
messages: Belongs to the UDP-galactopyranose/dTDP-fucopyranose mutase family.

2213200:BOX37 RS31620
gene id: 2213200:BOX37_RS31620
uniprot id: A0A1J0W037
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

2213200:BOX37 RS21095
gene id: 2213200:BOX37_RS21095
uniprot id: A0A1J0VVE4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

2213200:BOX37 RS25395
gene id: 2213200:BOX37_RS25395
uniprot id: A0A1J0VXA9
names: Function
names: Similarity
messages: Belongs to the PstS family.
messages: Involved in the system for phosphate transport across the cytoplasmic membrane.

2213200:BOX37 RS13615
gene id: 2213200:BOX37_RS13615
uniprot id: A0A1J0VS53
names: Similarity
messages: Belongs to the CFA/CMAS family.

2213200:BOX37 RS09475
gene id: 2213200:BOX37_RS09475
uniprot id: A0A1J0VQ97
names: Similarity
messages: Belongs to the AHA1 family.

2213200:BOX37 RS24500
gene id: 2213200:BOX37_RS24500
uniprot id: A0A1J0VWQ1
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family. MbtB subfamily.

2213200:BOX37 RS03735
gene id: 2213200:BOX37_RS03735
uniprot id: A0A1J0VMH8
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

2213200:BOX37 RS19730
gene id: 2213200:BOX37_RS19730
uniprot id: A0A1J0VUP1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

2213200:BOX37 RS04340
gene id: 2213200:BOX37_RS04340
uniprot id: A0A1J0VMR6
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

2213200:BOX37 RS19410
gene id: 2213200:BOX37_RS19410
uniprot id: A0A1J0VUN7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

2213200:BOX37 RS13090
gene id: 2213200:BOX37_RS13090
uniprot id: A0A1J0VRP8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

2213200:BOX37 RS22235
gene id: 2213200:BOX37_RS22235
uniprot id: A0A1J0VVW6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 2 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

2213200:BOX37 RS01160
gene id: 2213200:BOX37_RS01160
uniprot id: A0A1J0VL82
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2213200:BOX37 RS29045
gene id: 2213200:BOX37_RS29045
uniprot id: A0A1J0VYZ1
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
messages: Part of the 50S ribosomal subunit.

2213200:BOX37 RS02180
gene id: 2213200:BOX37_RS02180
uniprot id: A0A1J0VLS2
names: Similarity
messages: Belongs to the 4-hydroxy-2-oxovalerate aldolase family.

2213200:BOX37 RS32190
gene id: 2213200:BOX37_RS32190
uniprot id: A0A1J0W0K2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

2213200:BOX37 RS02575
gene id: 2213200:BOX37_RS02575
uniprot id: A0A1J0VLX2
names: Similarity
messages: Belongs to the EspG family.

2213200:BOX37 RS11165
gene id: 2213200:BOX37_RS11165
uniprot id: A0A1J0VQS4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2213200:BOX37 RS12330
gene id: 2213200:BOX37_RS12330
uniprot id: A0A1J0VRK9
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the RuBisCO large chain family. Type I subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterohexadecamer of 8 large chains and 8 small chains.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site.
messages: The basic functional RuBisCO is composed of a large chain homodimer in a 'head-to-tail' conformation. In form I RuBisCO this homodimer is arranged in a barrel-like tetramer with the small subunits forming a tetrameric 'cap' on each end of the 'barrel'.

2213200:BOX37 RS04910
gene id: 2213200:BOX37_RS04910
uniprot id: A0A1J0VN03
names: Similarity
messages: Belongs to the AccD/PCCB family.

2213200:BOX37 RS19215
gene id: 2213200:BOX37_RS19215
uniprot id: A0A1J0VUE9
names: Subcellular Location Annotation
messages: Membrane

2213200:BOX37 RS08550
gene id: 2213200:BOX37_RS08550
uniprot id: A0A1J0VPN0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CutC family.
messages: Cytoplasm
messages: Once thought to be involved in copper homeostasis, experiments in E.coli have shown this is not the case.

2213200:BOX37 RS26380
gene id: 2213200:BOX37_RS26380
uniprot id: A0A1J0VXJ9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

2213200:BOX37 RS10340
gene id: 2213200:BOX37_RS10340
uniprot id: A0A1J0VQI8
names: Similarity
messages: Belongs to the DNA glycosylase MPG family.

2213200:BOX37 RS02065
gene id: 2213200:BOX37_RS02065
uniprot id: A0A1J0VLR3
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

2213200:BOX37 RS01010
gene id: 2213200:BOX37_RS01010
uniprot id: A0A1J0VL78
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

2213200:BOX37 RS17945
gene id: 2213200:BOX37_RS17945
uniprot id: A0A1J0VTW5
names: Similarity
messages: Belongs to the asp23 family.

2213200:BOX37 RS00070
gene id: 2213200:BOX37_RS00070
uniprot id: A0A1J0VKT9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

2213200:BOX37 RS01580
gene id: 2213200:BOX37_RS01580
uniprot id: A0A1J0VLH2
names: Similarity
messages: Belongs to the Nudix hydrolase family. PCD1 subfamily.

2213200:BOX37 RS20455
gene id: 2213200:BOX37_RS20455
uniprot id: A0A1J0VVA9
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.

2213200:BOX37 RS18155
gene id: 2213200:BOX37_RS18155
uniprot id: A0A1J0VU06
names: Subcellular Location Annotation
messages: Membrane

2213200:BOX37 RS09490
gene id: 2213200:BOX37_RS09490
uniprot id: A0A1J0W1V4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2213200:BOX37 RS02550
gene id: 2213200:BOX37_RS02550
uniprot id: A0A1J0VLY8
names: Similarity
messages: Belongs to the WXG100 family.

2213200:BOX37 RS31480
gene id: 2213200:BOX37_RS31480
uniprot id: A0A1J0W072
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

2213200:BOX37 RS14625
gene id: 2213200:BOX37_RS14625
uniprot id: A0A1J0VSM7
names: PTM
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

2213200:BOX37 RS04615
gene id: 2213200:BOX37_RS04615
uniprot id: A0A1J0VMX3
names: Similarity
messages: Belongs to the barstar family.

2213200:BOX37 RS29920
gene id: 2213200:BOX37_RS29920
uniprot id: A0A1J0VZ39
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TPP enzyme family. MenD subfamily.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
messages: Homodimer.

2213200:BOX37 RS02600
gene id: 2213200:BOX37_RS02600
uniprot id: A0A1J0VLZ8
names: Similarity
messages: Belongs to the GARS family.

2213200:BOX37 RS29785
gene id: 2213200:BOX37_RS29785
uniprot id: A0A1J0VZC0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

2213200:BOX37 RS27835
gene id: 2213200:BOX37_RS27835
uniprot id: A0A1J0VY93
names: Similarity
messages: Belongs to the cytochrome P450 family.

2213200:BOX37 RS03685
gene id: 2213200:BOX37_RS03685
uniprot id: A0A1J0W156
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

2213200:BOX37 RS20040
gene id: 2213200:BOX37_RS20040
uniprot id: A0A1J0W2L1
names: Similarity
messages: Belongs to the Nudix hydrolase family.

2213200:BOX37 RS32835
gene id: 2213200:BOX37_RS32835
uniprot id: A0A1J0W3N9
names: Similarity
names: Subunit
messages: Belongs to the RNase H family.
messages: Monomer.

2213200:BOX37 RS02990
gene id: 2213200:BOX37_RS02990
uniprot id: A0A1J0VM61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPAT/DAPAT family.
messages: Cell membrane
messages: Membrane

2213200:BOX37 RS04555
gene id: 2213200:BOX37_RS04555
uniprot id: A0A1J0VMX4
names: Cofactor
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

2213200:BOX37 RS30795
gene id: 2213200:BOX37_RS30795
uniprot id: A0A1J0VZH8
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

2213200:BOX37 RS21270
gene id: 2213200:BOX37_RS21270
uniprot id: A0A1J0VVB5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

2213200:BOX37 RS30905
gene id: 2213200:BOX37_RS30905
uniprot id: A0A1J0VZM8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

2213200:BOX37 RS20305
gene id: 2213200:BOX37_RS20305
uniprot id: A0A1J0VUX1
names: Similarity
messages: Belongs to the iron/ascorbate-dependent oxidoreductase family.

2213200:BOX37 RS12725
gene id: 2213200:BOX37_RS12725
uniprot id: A0A1J0VRS3
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.

2213200:BOX37 RS29240
gene id: 2213200:BOX37_RS29240
uniprot id: A0A1J0VZ18
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

2213200:BOX37 RS00920
gene id: 2213200:BOX37_RS00920
uniprot id: A0A1J0VL49
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

2213200:BOX37 RS18480
gene id: 2213200:BOX37_RS18480
uniprot id: A0A1J0VU60
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

2213200:BOX37 RS04860
gene id: 2213200:BOX37_RS04860
uniprot id: A0A1J0VN21
names: Similarity
names: Subunit
messages: Belongs to the aldehyde dehydrogenase family.
messages: Homotetramer.

2213200:BOX37 RS01625
gene id: 2213200:BOX37_RS01625
uniprot id: A0A1J0VLI4
names: Similarity
messages: Belongs to the GSP E family.

2213200:BOX37 RS17170
gene id: 2213200:BOX37_RS17170
uniprot id: A0A1J0VTH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

2213200:BOX37 RS18160
gene id: 2213200:BOX37_RS18160
uniprot id: A0A1J0VU93
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

2213200:BOX37 RS27500
gene id: 2213200:BOX37_RS27500
uniprot id: A0A1J0VY16
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

2213200:BOX37 RS09800
gene id: 2213200:BOX37_RS09800
uniprot id: A0A1J0VQ73
names: Similarity
messages: Belongs to the thioredoxin family.

2213200:BOX37 RS29235
gene id: 2213200:BOX37_RS29235
uniprot id: A0A1J0VZ43
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

2213200:BOX37 RS31440
gene id: 2213200:BOX37_RS31440
uniprot id: A0A1J0W005
names: Caution
names: Similarity
messages: Belongs to the globin family. Two-domain flavohemoproteins subfamily.
messages: In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2213200:BOX37 RS17825
gene id: 2213200:BOX37_RS17825
uniprot id: A0A1J0VTT2
names: Cofactor
names: Similarity
messages: Belongs to the carotenoid oxygenase family.
messages: Binds 1 Fe(2+) ion per subunit.

2213200:BOX37 RS12560
gene id: 2213200:BOX37_RS12560
uniprot id: A0A1J0VRP9
names: Function
names: Similarity
messages: Belongs to the ectoine synthase family.
messages: Catalyzes the circularization of gamma-N-acetyl-alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6-tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant.

2213200:BOX37 RS25185
gene id: 2213200:BOX37_RS25185
uniprot id: A0A1J0VX56
names: Similarity
messages: Belongs to the HMG-CoA lyase family.
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

2213200:BOX37 RS32140
gene id: 2213200:BOX37_RS32140
uniprot id: A0A1J0W055
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

2213200:BOX37 RS12360
gene id: 2213200:BOX37_RS12360
uniprot id: A0A1J0VRE1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

2213200:BOX37 RS27510
gene id: 2213200:BOX37_RS27510
uniprot id: A0A1J0VYA8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2213200:BOX37 RS02695
gene id: 2213200:BOX37_RS02695
uniprot id: A0A1J0VLZ5
names: Similarity
messages: Belongs to the peptidase M18 family.

2213200:BOX37 RS09700
gene id: 2213200:BOX37_RS09700
uniprot id: A0A1J0VQ52
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

2213200:BOX37 RS23340
gene id: 2213200:BOX37_RS23340
uniprot id: A0A1J0VWD8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
messages: Membrane

2213200:BOX37 RS11630
gene id: 2213200:BOX37_RS11630
uniprot id: A0A1J0VQZ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

2213200:BOX37 RS21995
gene id: 2213200:BOX37_RS21995
uniprot id: A0A1J0VVQ3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

2213200:BOX37 RS22475
gene id: 2213200:BOX37_RS22475
uniprot id: A0A1J0VW07
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

2213200:BOX37 RS29410
gene id: 2213200:BOX37_RS29410
uniprot id: A0A1J0VZ61
names: Subcellular Location Annotation
messages: Membrane

2213200:BOX37 RS11925
gene id: 2213200:BOX37_RS11925
uniprot id: A0A1J0VR52
names: Similarity
messages: Belongs to the non-flavoprotein flavin reductase family.

2213200:BOX37 RS09600
gene id: 2213200:BOX37_RS09600
uniprot id: A0A1J0VQ68
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

2213200:BOX37 RS21350
gene id: 2213200:BOX37_RS21350
uniprot id: A0A1J0VVC6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

2213200:BOX37 RS20585
gene id: 2213200:BOX37_RS20585
uniprot id: A0A1J0VV76
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2213200:BOX37 RS20500
gene id: 2213200:BOX37_RS20500
uniprot id: A0A1J0VUZ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

2213200:BOX37 RS11115
gene id: 2213200:BOX37_RS11115
uniprot id: A0A1J0VQV1
names: Subcellular Location Annotation
messages: Membrane

2213200:BOX37 RS15585
gene id: 2213200:BOX37_RS15585
uniprot id: A0A1J0VSS2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

2213200:BOX37 RS09045
gene id: 2213200:BOX37_RS09045
uniprot id: A0A1J0VPV9
names: Similarity
messages: Belongs to the AHA1 family.

2213200:BOX37 RS12550
gene id: 2213200:BOX37_RS12550
uniprot id: A0A1J0VRH3
names: Function
names: Similarity
messages: Belongs to the acetyltransferase family. EctA subfamily.
messages: Catalyzes the acetylation of L-2,4-diaminobutyrate (DABA) to gamma-N-acetyl-alpha,gamma-diaminobutyric acid (ADABA) with acetyl coenzyme A.

2213200:BOX37 RS13730
gene id: 2213200:BOX37_RS13730
uniprot id: A0A1J0VRX8
names: Similarity
messages: Belongs to the glutamate synthase family.

2213200:BOX37 RS29765
gene id: 2213200:BOX37_RS29765
uniprot id: A0A1J0VZD3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

2213200:BOX37 RS01800
gene id: 2213200:BOX37_RS01800
uniprot id: A0A1J0VLL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

2213200:BOX37 RS19695
gene id: 2213200:BOX37_RS19695
uniprot id: A0A1J0VUR0
names: Subcellular Location Annotation
messages: Membrane

2213200:BOX37 RS31055
gene id: 2213200:BOX37_RS31055
uniprot id: A0A1J0W3M5
names: Similarity
messages: Belongs to the adenylyl cyclase class-3 family.

2213200:BOX37 RS09200
gene id: 2213200:BOX37_RS09200
uniprot id: A0A1J0VPY5
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

2213200:BOX37 RS23525
gene id: 2213200:BOX37_RS23525
uniprot id: A0A1J0VWD6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

2213200:BOX37 RS18650
gene id: 2213200:BOX37_RS18650
uniprot id: A0A1J0VU81
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

2213200:BOX37 RS23060
gene id: 2213200:BOX37_RS23060
uniprot id: A0A1J0VW52
names: Subcellular Location Annotation
messages: Membrane

2213200:BOX37 RS25445
gene id: 2213200:BOX37_RS25445
uniprot id: A0A1J0VX42
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

2213200:BOX37 RS08730
gene id: 2213200:BOX37_RS08730
uniprot id: A0A1J0VPR3
names: Function
names: Similarity
messages: Belongs to the nucleoside phosphorylase PpnP family.
messages: Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions.

2213200:BOX37 RS31000
gene id: 2213200:BOX37_RS31000
uniprot id: A0A1J0VZV6
names: Function
messages: Catalyzes the phosphorylation of hydroxymethylpyrimidine phosphate (HMP-P) to HMP-PP, and of HMP to HMP-P.

2213200:BOX37 RS15725
gene id: 2213200:BOX37_RS15725
uniprot id: A0A1J0VSU8
names: Similarity
messages: Belongs to the DNA polymerase type-A family.

2213200:BOX37 RS30105
gene id: 2213200:BOX37_RS30105
uniprot id: A0A1J0VZA8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transcriptional regulatory Rex family.
messages: Cytoplasm
messages: Homodimer.
messages: Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.

2213200:BOX37 RS07675
gene id: 2213200:BOX37_RS07675
uniprot id: A0A1J0VPF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

2213200:BOX37 RS30935
gene id: 2213200:BOX37_RS30935
uniprot id: A0A1J0VZY4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

2213200:BOX37 RS27955
gene id: 2213200:BOX37_RS27955
uniprot id: A0A1J0VYA2
names: Subcellular Location Annotation
messages: Membrane

2213200:BOX37 RS03750
gene id: 2213200:BOX37_RS03750
uniprot id: A0A1J0VMH5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

2213200:BOX37 RS30785
gene id: 2213200:BOX37_RS30785
uniprot id: A0A1J0W3J6
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

2213200:BOX37 RS04650
gene id: 2213200:BOX37_RS04650
uniprot id: A0A1J0VMW1
names: Similarity
messages: Belongs to the peptidase S11 family.

2213200:BOX37 RS17375
gene id: 2213200:BOX37_RS17375
uniprot id: A0A1J0VTQ2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

2213200:BOX37 RS11135
gene id: 2213200:BOX37_RS11135
uniprot id: A0A1J0VQU4
names: Cofactor
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
messages: Binds 2 nickel ions per subunit.
messages: Carbamylation allows a single lysine to coordinate two nickel ions.
messages: Carboxylation allows a single lysine to coordinate two nickel ions.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

2213200:BOX37 RS21125
gene id: 2213200:BOX37_RS21125
uniprot id: A0A1J0W2M9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2213200:BOX37 RS04280
gene id: 2213200:BOX37_RS04280
uniprot id: A0A1J0W181
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

2213200:BOX37 RS15795
gene id: 2213200:BOX37_RS15795
uniprot id: A0A1J0VSY8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

2213200:BOX37 RS18920
gene id: 2213200:BOX37_RS18920
uniprot id: A0A1J0VUD2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

2213200:BOX37 RS26200
gene id: 2213200:BOX37_RS26200
uniprot id: A0A1J0VXG7
names: Cofactor
names: Similarity
messages: Belongs to the fatty acid desaturase type 2 family.
messages: Binds 2 iron ions per subunit.

2213200:BOX37 RS19835
gene id: 2213200:BOX37_RS19835
uniprot id: A0A1J0VUP5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

2213200:BOX37 RS31275
gene id: 2213200:BOX37_RS31275
uniprot id: A0A1J0W075
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

2213200:BOX37 RS10820
gene id: 2213200:BOX37_RS10820
uniprot id: A0A1J0VQW0
names: Similarity
messages: Belongs to the creatininase superfamily.

2213200:BOX37 RS25980
gene id: 2213200:BOX37_RS25980
uniprot id: A0A1J0VXE5
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

2213200:BOX37 RS14510
gene id: 2213200:BOX37_RS14510
uniprot id: A0A1J0VSD3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

2213200:BOX37 RS19825
gene id: 2213200:BOX37_RS19825
uniprot id: A0A1J0VUT2
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

2213200:BOX37 RS16385
gene id: 2213200:BOX37_RS16385
uniprot id: A0A1J0VT44
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

2213200:BOX37 RS10990
gene id: 2213200:BOX37_RS10990
uniprot id: A0A1J0VQT1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2213200:BOX37 RS01080
gene id: 2213200:BOX37_RS01080
uniprot id: A0A1J0VLA3
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

2213200:BOX37 RS32280
gene id: 2213200:BOX37_RS32280
uniprot id: A0A1J0W078
names: Similarity
messages: Belongs to the glycosyl hydrolase 25 family.

2213200:BOX37 RS21535
gene id: 2213200:BOX37_RS21535
uniprot id: A0A1J0W2U7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2213200:BOX37 RS32595
gene id: 2213200:BOX37_RS32595
uniprot id: A0A1J0W402
names: Subcellular Location Annotation
messages: Membrane

2213200:BOX37 RS30390
gene id: 2213200:BOX37_RS30390
uniprot id: A0A1J0VZT0
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

2213200:BOX37 RS20745
gene id: 2213200:BOX37_RS20745
uniprot id: A0A1J0VV94
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

2213200:BOX37 RS15510
gene id: 2213200:BOX37_RS15510
uniprot id: A0A1J0VSS6
names: Subcellular Location Annotation
messages: Membrane

2213200:BOX37 RS22670
gene id: 2213200:BOX37_RS22670
uniprot id: A0A1J0VW24
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.

2213200:BOX37 RS23700
gene id: 2213200:BOX37_RS23700
uniprot id: A0A1J0VWF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0182 family.
messages: Cell membrane

2213200:BOX37 RS11665
gene id: 2213200:BOX37_RS11665
uniprot id: A0A1J0VR98
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
messages: Cytoplasm
messages: The 20S proteasome core is composed of 14 alpha and 14 beta subunits that assemble into four stacked heptameric rings, resulting in a barrel-shaped structure. The two inner rings, each composed of seven catalytic beta subunits, are sandwiched by two outer rings, each composed of seven alpha subunits. The catalytic chamber with the active sites is on the inside of the barrel. Has a gated structure, the ends of the cylinder being occluded by the N-termini of the alpha-subunits. Is capped by the proteasome-associated ATPase, ARC.
messages: The formation of the proteasomal ATPase ARC-20S proteasome complex, likely via the docking of the C-termini of ARC into the intersubunit pockets in the alpha-rings, may trigger opening of the gate for substrate entry. Interconversion between the open-gate and close-gate conformations leads to a dynamic regulation of the 20S proteasome proteolysis activity.

2213200:BOX37 RS19365
gene id: 2213200:BOX37_RS19365
uniprot id: A0A1J0VUJ1
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

2213200:BOX37 RS31975
gene id: 2213200:BOX37_RS31975
uniprot id: A0A1J0W0G6
names: Similarity
messages: Belongs to the isochorismate synthase family.

2213200:BOX37 RS08560
gene id: 2213200:BOX37_RS08560
uniprot id: A0A1J0VPQ0
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

2213200:BOX37 RS14545
gene id: 2213200:BOX37_RS14545
uniprot id: A0A1J0VSC7
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

2213200:BOX37 RS05425
gene id: 2213200:BOX37_RS05425
uniprot id: A0A1J0VN97
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2213200:BOX37 RS30380
gene id: 2213200:BOX37_RS30380
uniprot id: A0A1J0VZK3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

2213200:BOX37 RS12305
gene id: 2213200:BOX37_RS12305
uniprot id: A0A1J0VRB2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

2213200:BOX37 RS30680
gene id: 2213200:BOX37_RS30680
uniprot id: A0A1J0VZQ2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2213200:BOX37 RS11610
gene id: 2213200:BOX37_RS11610
uniprot id: A0A1J0VQZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2213200:BOX37 RS10755
gene id: 2213200:BOX37_RS10755
uniprot id: A0A1J0VQV5
names: Similarity
messages: Belongs to the peptidase A31 family.

2213200:BOX37 RS25770
gene id: 2213200:BOX37_RS25770
uniprot id: A0A1J0VXP9
names: Function
names: Similarity
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

2213200:BOX37 RS13135
gene id: 2213200:BOX37_RS13135
uniprot id: A0A1J0VRS6
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: Could possibly oxidize fatty acids using specific components.

2213200:BOX37 RS04445
gene id: 2213200:BOX37_RS04445
uniprot id: A0A1J0VMV4
names: Similarity
messages: Belongs to the IMPDH/GMPR family.

2213200:BOX37 RS31390
gene id: 2213200:BOX37_RS31390
uniprot id: A0A1J0VZS7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2213200:BOX37 RS07650
gene id: 2213200:BOX37_RS07650
uniprot id: A0A1J0VPB1
names: Similarity
messages: In the C-terminal section; belongs to the anthranilate synthase component I family.

2213200:BOX37 RS04410
gene id: 2213200:BOX37_RS04410
uniprot id: A0A1J0VMR4
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

2213200:BOX37 RS11195
gene id: 2213200:BOX37_RS11195
uniprot id: A0A1J0VQT2
names: Similarity
messages: Belongs to the cytochrome P450 family.

2213200:BOX37 RS24335
gene id: 2213200:BOX37_RS24335
uniprot id: A0A1J0W2Z4
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

2213200:BOX37 RS05070
gene id: 2213200:BOX37_RS05070
uniprot id: A0A1J0VN46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

2213200:BOX37 RS29030
gene id: 2213200:BOX37_RS29030
uniprot id: A0A1J0W3E6
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

2213200:BOX37 RS23470
gene id: 2213200:BOX37_RS23470
uniprot id: A0A1J0VWG3
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

2213200:BOX37 RS19195
gene id: 2213200:BOX37_RS19195
uniprot id: A0A1J0VUS4
names: Subcellular Location Annotation
messages: Membrane

2213200:BOX37 RS14865
gene id: 2213200:BOX37_RS14865
uniprot id: A0A1J0VSR6
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

2213200:BOX37 RS09930
gene id: 2213200:BOX37_RS09930
uniprot id: A0A1J0VQ98
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

2213200:BOX37 RS07920
gene id: 2213200:BOX37_RS07920
uniprot id: A0A1J0VPE6
names: Function
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

2213200:BOX37 RS15915
gene id: 2213200:BOX37_RS15915
uniprot id: A0A1J0VSX7
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 5 (UDGb) family.

2213200:BOX37 RS13205
gene id: 2213200:BOX37_RS13205
uniprot id: A0A1J0VRQ0
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

2213200:BOX37 RS00985
gene id: 2213200:BOX37_RS00985
uniprot id: A0A1J0VL57
names: Similarity
names: Subunit
messages: Belongs to the Bpa family.
messages: Forms a homooligomeric, either hexameric or heptameric, ring-like structure which stacks co-axially with the proteasomal alpha-rings.

2213200:BOX37 RS08740
gene id: 2213200:BOX37_RS08740
uniprot id: A0A1J0VPT9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

2213200:BOX37 RS02880
gene id: 2213200:BOX37_RS02880
uniprot id: A0A1J0VM31
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

2213200:BOX37 RS22170
gene id: 2213200:BOX37_RS22170
uniprot id: A0A1J0W2R9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

2213200:BOX37 RS01760
gene id: 2213200:BOX37_RS01760
uniprot id: A0A1J0VLI9
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

2213200:BOX37 RS24760
gene id: 2213200:BOX37_RS24760
uniprot id: A0A1J0W343
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

2213200:BOX37 RS12565
gene id: 2213200:BOX37_RS12565
uniprot id: A0A1J0VRF5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PhyH family. EctD subfamily.
messages: Homodimer.
messages: Involved in the biosynthesis of 5-hydroxyectoine, called compatible solute, which helps organisms to survive extreme osmotic stress by acting as a highly soluble organic osmolyte. Catalyzes the 2-oxoglutarate-dependent selective hydroxylation of L-ectoine to yield (4S,5S)-5-hydroxyectoine.

2213200:BOX37 RS02350
gene id: 2213200:BOX37_RS02350
uniprot id: A0A1J0VLV9
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

2213200:BOX37 RS25585
gene id: 2213200:BOX37_RS25585
uniprot id: A0A1J0VXE3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.
messages: In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: In the N-terminal section; belongs to the MIP18 family.

2213200:BOX37 RS32540
gene id: 2213200:BOX37_RS32540
uniprot id: A0A1J0W0I6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

2213200:BOX37 RS05395
gene id: 2213200:BOX37_RS05395
uniprot id: A0A1J0VN93
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

2213200:BOX37 RS10725
gene id: 2213200:BOX37_RS10725
uniprot id: A0A1J0VQM4
names: Similarity
names: Subunit
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase small subunit family.
messages: Heterodimer of a large and a small subunit.

2213200:BOX37 RS15675
gene id: 2213200:BOX37_RS15675
uniprot id: A0A1J0VT50
names: Similarity
messages: Belongs to the FAD-binding monooxygenase family.

2213200:BOX37 RS20055
gene id: 2213200:BOX37_RS20055
uniprot id: A0A1J0VUY6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Catalyzes the conjugation of the 1'-hydroxyl group of D-myo-inositol-3-phosphate (also named L-myo-inositol-1-phosphate) with a lipid tail of cytidine diphosphate diacylglycerol (CDP-DAG), forming phosphatidylinositol phosphate (PIP) and CMP. PIP is a precursor of phosphatidylinositol (PI) which is an essential lipid required for cell wall formation.
messages: Cell membrane
messages: Contains a di-nuclear catalytic Mg(2+) center.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

2213200:BOX37 RS17780
gene id: 2213200:BOX37_RS17780
uniprot id: A0A1J0VTS4
names: Subcellular Location Annotation
messages: Membrane

2213200:BOX37 RS02995
gene id: 2213200:BOX37_RS02995
uniprot id: A0A1J0VM50
names: Similarity
messages: Belongs to the AccD/PCCB family.

2213200:BOX37 RS11300
gene id: 2213200:BOX37_RS11300
uniprot id: A0A1J0VQY5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

2213200:BOX37 RS23090
gene id: 2213200:BOX37_RS23090
uniprot id: A0A1J0VW99
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpC family.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

2213200:BOX37 RS15265
gene id: 2213200:BOX37_RS15265
uniprot id: A0A1J0W264
names: Subcellular Location Annotation
messages: Membrane

2213200:BOX37 RS01890
gene id: 2213200:BOX37_RS01890
uniprot id: A0A1J0VLL2
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

2213200:BOX37 RS01770
gene id: 2213200:BOX37_RS01770
uniprot id: A0A1J0VLL4
names: Subcellular Location Annotation
messages: Membrane

2213200:BOX37 RS00425
gene id: 2213200:BOX37_RS00425
uniprot id: A0A1J0W108
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.
messages: Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.

2213200:BOX37 RS16245
gene id: 2213200:BOX37_RS16245
uniprot id: A0A1J0VT29
names: Subcellular Location Annotation
messages: Membrane

2213200:BOX37 RS18490
gene id: 2213200:BOX37_RS18490
uniprot id: A0A1J0VU39
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

2213200:BOX37 RS21030
gene id: 2213200:BOX37_RS21030
uniprot id: A0A1J0VV79
names: Similarity
messages: Belongs to the pirin family.

2213200:BOX37 RS30470
gene id: 2213200:BOX37_RS30470
uniprot id: A0A1J0VZJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

2213200:BOX37 RS19325
gene id: 2213200:BOX37_RS19325
uniprot id: A0A1J0VUI0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

2213200:BOX37 RS21510
gene id: 2213200:BOX37_RS21510
uniprot id: A0A1J0VVF0
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family.

2213200:BOX37 RS02860
gene id: 2213200:BOX37_RS02860
uniprot id: A0A1J0VM36
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PstS family.
messages: Part of the ABC transporter complex PstSACB involved in phosphate import.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

2213200:BOX37 RS06580
gene id: 2213200:BOX37_RS06580
uniprot id: A0A1J0VNT6
names: Similarity
messages: Belongs to the peptidase M1 family.

2213200:BOX37 RS09165
gene id: 2213200:BOX37_RS09165
uniprot id: A0A1J0VPX6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

2213200:BOX37 RS11520
gene id: 2213200:BOX37_RS11520
uniprot id: A0A1J0W1U4
names: Similarity
messages: Belongs to the carnitine/choline acetyltransferase family.

2213200:BOX37 RS14850
gene id: 2213200:BOX37_RS14850
uniprot id: A0A1J0VSG5
names: Similarity
messages: Belongs to the CdaR family.

2213200:BOX37 RS26045
gene id: 2213200:BOX37_RS26045
uniprot id: A0A1J0VXK4
names: Subcellular Location Annotation
messages: Membrane

2213200:BOX37 RS31130
gene id: 2213200:BOX37_RS31130
uniprot id: A0A1J0W017
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

2213200:BOX37 RS15195
gene id: 2213200:BOX37_RS15195
uniprot id: A0A1J0W2B7
names: Similarity
messages: Belongs to the cytochrome P450 family.

2213200:BOX37 RS10345
gene id: 2213200:BOX37_RS10345
uniprot id: A0A1J0W1R5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

2213200:BOX37 RS30570
gene id: 2213200:BOX37_RS30570
uniprot id: A0A1J0VZQ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.
messages: Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU).
messages: Homotetramer.

2213200:BOX37 RS20775
gene id: 2213200:BOX37_RS20775
uniprot id: A0A1J0VVF6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

2213200:BOX37 RS12605
gene id: 2213200:BOX37_RS12605
uniprot id: A0A1J0VRI2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2213200:BOX37 RS09285
gene id: 2213200:BOX37_RS09285
uniprot id: A0A1J0VPY8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

2213200:BOX37 RS01165
gene id: 2213200:BOX37_RS01165
uniprot id: A0A1J0VLC0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.
messages: Cell membrane
messages: Involved in the import of queuosine (Q) precursors, required for Q precursor salvage.

2213200:BOX37 RS08340
gene id: 2213200:BOX37_RS08340
uniprot id: A0A1J0VPK0
names: Similarity
messages: Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family.

2213200:BOX37 RS24765
gene id: 2213200:BOX37_RS24765
uniprot id: A0A1J0VWZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

2213200:BOX37 RS18360
gene id: 2213200:BOX37_RS18360
uniprot id: A0A1J0VU16
names: Similarity
messages: Belongs to the TfdA dioxygenase family.

2213200:BOX37 RS09515
gene id: 2213200:BOX37_RS09515
uniprot id: A0A1J0VQ47
names: Similarity
messages: Belongs to the F420H(2)-dependent quinone reductase family.

2213200:BOX37 RS27845
gene id: 2213200:BOX37_RS27845
uniprot id: A0A1J0VYF6
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

2213200:BOX37 RS04415
gene id: 2213200:BOX37_RS04415
uniprot id: A0A1J0VMR5
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

2213200:BOX37 RS22815
gene id: 2213200:BOX37_RS22815
uniprot id: A0A1J0VW15
names: Similarity
messages: Belongs to the site-specific recombinase resolvase family.

2213200:BOX37 RS12985
gene id: 2213200:BOX37_RS12985
uniprot id: A0A1J0VRN7
names: Function
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.

2213200:BOX37 RS03200
gene id: 2213200:BOX37_RS03200
uniprot id: A0A1J0VM79
names: Similarity
messages: Belongs to the citrate synthase family.

2213200:BOX37 RS02985
gene id: 2213200:BOX37_RS02985
uniprot id: A0A1J0VM52
names: Domain
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

2213200:BOX37 RS19125
gene id: 2213200:BOX37_RS19125
uniprot id: A0A1J0VUR5
names: Subcellular Location Annotation
messages: Membrane

2213200:BOX37 RS04760
gene id: 2213200:BOX37_RS04760
uniprot id: A0A1J0VMZ7
names: Similarity
messages: Belongs to the UPRTase family.

2213200:BOX37 RS31410
gene id: 2213200:BOX37_RS31410
uniprot id: A0A1J0VZW6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

2213200:BOX37 RS09690
gene id: 2213200:BOX37_RS09690
uniprot id: A0A1J0VQ58
names: Similarity
messages: Belongs to the TrpC family.

2213200:BOX37 RS30650
gene id: 2213200:BOX37_RS30650
uniprot id: A0A1J0VZF8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

2213200:BOX37 RS16365
gene id: 2213200:BOX37_RS16365
uniprot id: A0A1J0VT61
names: Similarity
messages: Belongs to the ThrE exporter (TC 2.A.79) family.

2213200:BOX37 RS13410
gene id: 2213200:BOX37_RS13410
uniprot id: A0A1J0VRU3
names: Similarity
messages: Belongs to the PhoU family.

2213200:BOX37 RS10875
gene id: 2213200:BOX37_RS10875
uniprot id: A0A1J0VQP2
names: Function
messages: TetR is the repressor of the tetracycline resistance element; its N-terminal region forms a helix-turn-helix structure and binds DNA. Binding of tetracycline to TetR reduces the repressor affinity for the tetracycline resistance gene (tetA) promoter operator sites.

2213200:BOX37 RS30805
gene id: 2213200:BOX37_RS30805
uniprot id: A0A1J0VZQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

2213200:BOX37 RS06520
gene id: 2213200:BOX37_RS06520
uniprot id: A0A1J0VNS7
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

2213200:BOX37 RS00395
gene id: 2213200:BOX37_RS00395
uniprot id: A0A1J0VKY5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

2213200:BOX37 RS11680
gene id: 2213200:BOX37_RS11680
uniprot id: A0A1J0VR42
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

2213200:BOX37 RS09965
gene id: 2213200:BOX37_RS09965
uniprot id: A0A1J0VQD1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

2213200:BOX37 RS21285
gene id: 2213200:BOX37_RS21285
uniprot id: A0A1J0VVM8
names: Subcellular Location Annotation
messages: Membrane

2213200:BOX37 RS06220
gene id: 2213200:BOX37_RS06220
uniprot id: A0A1J0VNJ8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

2213200:BOX37 RS29225
gene id: 2213200:BOX37_RS29225
uniprot id: A0A1J0VZA5
names: Similarity
messages: Belongs to the FPG family.

2213200:BOX37 RS18575
gene id: 2213200:BOX37_RS18575
uniprot id: A0A1J0VU59
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

2213200:BOX37 RS04455
gene id: 2213200:BOX37_RS04455
uniprot id: A0A1J0VMS9
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

2213200:BOX37 RS20230
gene id: 2213200:BOX37_RS20230
uniprot id: A0A1J0VV77
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

2213200:BOX37 RS14820
gene id: 2213200:BOX37_RS14820
uniprot id: A0A1J0VSQ9
names: Similarity
messages: Belongs to the cytochrome P450 family.

2213200:BOX37 RS30490
gene id: 2213200:BOX37_RS30490
uniprot id: A0A1J0VZF7
names: Cofactor
messages: Can also use Mn(2+) ion.

2213200:BOX37 RS12920
gene id: 2213200:BOX37_RS12920
uniprot id: A0A1J0VRM5
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

2213200:BOX37 RS14100
gene id: 2213200:BOX37_RS14100
uniprot id: A0A1J0VSE2
names: Similarity
messages: Belongs to the universal stress protein A family.

2213200:BOX37 RS05330
gene id: 2213200:BOX37_RS05330
uniprot id: A0A1J0VNA5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

2213200:BOX37 RS04605
gene id: 2213200:BOX37_RS04605
uniprot id: A0A1J0VMV3
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

2213200:BOX37 RS11740
gene id: 2213200:BOX37_RS11740
uniprot id: A0A1J0VR39
names: Similarity
messages: Belongs to the peptidase M24B family.

2213200:BOX37 RS00020
gene id: 2213200:BOX37_RS00020
uniprot id: A0A1J0W0K7
names: Similarity
messages: Belongs to the UPF0232 family.

2213200:BOX37 RS01380
gene id: 2213200:BOX37_RS01380
uniprot id: A0A1J0VLG1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2213200:BOX37 RS30860
gene id: 2213200:BOX37_RS30860
uniprot id: A0A1J0VZM1
names: Subcellular Location Annotation
messages: Membrane

2213200:BOX37 RS21805
gene id: 2213200:BOX37_RS21805
uniprot id: A0A1J0VVN4
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2213200:BOX37 RS08985
gene id: 2213200:BOX37_RS08985
uniprot id: A0A1J0VPV6
names: Similarity
messages: Belongs to the peptidase C40 family.

2213200:BOX37 RS01440
gene id: 2213200:BOX37_RS01440
uniprot id: A0A1J0VLF6
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

2213200:BOX37 RS01255
gene id: 2213200:BOX37_RS01255
uniprot id: A0A1J0VLA4
names: Subcellular Location Annotation
messages: Membrane

2213200:BOX37 RS20625
gene id: 2213200:BOX37_RS20625
uniprot id: A0A1J0W2U1
names: Subcellular Location Annotation
messages: Membrane

2213200:BOX37 RS11780
gene id: 2213200:BOX37_RS11780
uniprot id: A0A1J0VR46
names: Similarity
messages: Belongs to the CobH/CbiC family.

2213200:BOX37 RS10140
gene id: 2213200:BOX37_RS10140
uniprot id: A0A1J0VQD5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

2213200:BOX37 RS03410
gene id: 2213200:BOX37_RS03410
uniprot id: A0A1J0VMB6
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

2213200:BOX37 RS29595
gene id: 2213200:BOX37_RS29595
uniprot id: A0A1J0VZ28
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

2213200:BOX37 RS15090
gene id: 2213200:BOX37_RS15090
uniprot id: A0A1J0VSK7
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: Could possibly oxidize fatty acids using specific components.

2213200:BOX37 RS20605
gene id: 2213200:BOX37_RS20605
uniprot id: A0A1J0VV50
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

2213200:BOX37 RS07985
gene id: 2213200:BOX37_RS07985
uniprot id: A0A1J0W1H7
names: Function
names: Similarity
messages: Belongs to the AlaDH/PNT family.
messages: Catalyzes the reversible reductive amination of pyruvate to L-alanine.

2213200:BOX37 RS19245
gene id: 2213200:BOX37_RS19245
uniprot id: A0A1J0VUF4
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2213200:BOX37 RS10460
gene id: 2213200:BOX37_RS10460
uniprot id: A0A1J0VQK6
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

2213200:BOX37 RS33095
gene id: 2213200:BOX37_RS33095
uniprot id: A0A1J0W0N0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

2213200:BOX37 RS09160
gene id: 2213200:BOX37_RS09160
uniprot id: A0A1J0VPX8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

2213200:BOX37 RS20895
gene id: 2213200:BOX37_RS20895
uniprot id: A0A1J0VV91
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily.
messages: Belongs to the spermidine/spermine synthase family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
messages: Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
messages: Heterotetramer of two alpha and two beta chains arranged as a dimer of alpha/beta heterodimers.
messages: Homodimer or homotetramer.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl group blocking the N-terminus of the alpha chain.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2213200:BOX37 RS29060
gene id: 2213200:BOX37_RS29060
uniprot id: A0A1J0VZ02
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

2213200:BOX37 RS10315
gene id: 2213200:BOX37_RS10315
uniprot id: A0A1J0VQG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

2213200:BOX37 RS25475
gene id: 2213200:BOX37_RS25475
uniprot id: A0A1J0VXA2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cutinase family.
messages: Catalyzes the hydrolysis of complex carboxylic polyesters found in the cell wall of plants. Degrades cutin, a macromolecule that forms the structure of the plant cuticle.
messages: Secreted

2213200:BOX37 RS13000
gene id: 2213200:BOX37_RS13000
uniprot id: A0A1J0VRW7
names: Similarity
messages: Belongs to the NtaA/SnaA/DszA monooxygenase family.

2213200:BOX37 RS11230
gene id: 2213200:BOX37_RS11230
uniprot id: A0A1J0VQW1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
messages: Cytoplasm
messages: Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
messages: Homodimer. UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

2213200:BOX37 RS24920
gene id: 2213200:BOX37_RS24920
uniprot id: A0A1J0VXA8
names: Similarity
messages: Belongs to the long-chain O-acyltransferase family.

2213200:BOX37 RS06690
gene id: 2213200:BOX37_RS06690
uniprot id: A0A1J0VNU6
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

2213200:BOX37 RS04765
gene id: 2213200:BOX37_RS04765
uniprot id: A0A1J0VMX1
names: Similarity
messages: Belongs to the phosphohexose mutase family.

2213200:BOX37 RS07165
gene id: 2213200:BOX37_RS07165
uniprot id: A0A1J0VP05
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

2213200:BOX37 RS14415
gene id: 2213200:BOX37_RS14415
uniprot id: A0A1J0VS99
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: Could possibly oxidize fatty acids using specific components.

2213200:BOX37 RS01945
gene id: 2213200:BOX37_RS01945
uniprot id: A0A1J0VLN1
names: Subcellular Location Annotation
messages: Membrane

2213200:BOX37 RS08825
gene id: 2213200:BOX37_RS08825
uniprot id: A0A1J0VPV1
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

2213200:BOX37 RS30455
gene id: 2213200:BOX37_RS30455
uniprot id: A0A1J0VZT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VKOR family.
messages: Membrane

2213200:BOX37 RS05035
gene id: 2213200:BOX37_RS05035
uniprot id: A0A1J0VN44
names: Subcellular Location Annotation
messages: Membrane

2213200:BOX37 RS02080
gene id: 2213200:BOX37_RS02080
uniprot id: A0A1J0VLQ8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

2213200:BOX37 RS29370
gene id: 2213200:BOX37_RS29370
uniprot id: A0A1J0VZ45
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

2213200:BOX37 RS29780
gene id: 2213200:BOX37_RS29780
uniprot id: A0A1J0VZ60
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

2213200:BOX37 RS04920
gene id: 2213200:BOX37_RS04920
uniprot id: A0A1J0W125
names: Cofactor
names: Similarity
messages: Belongs to the fatty acid desaturase type 2 family.
messages: Binds 2 iron ions per subunit.

2213200:BOX37 RS20400
gene id: 2213200:BOX37_RS20400
uniprot id: A0A1J0VVA3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2213200:BOX37 RS02325
gene id: 2213200:BOX37_RS02325
uniprot id: A0A1J0VLT6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

2213200:BOX37 RS19595
gene id: 2213200:BOX37_RS19595
uniprot id: A0A1J0W2J8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

2213200:BOX37 RS28715
gene id: 2213200:BOX37_RS28715
uniprot id: A0A1J0W3E9
names: Similarity
messages: Belongs to the AB hydrolase superfamily. Lipase family.

2213200:BOX37 RS13600
gene id: 2213200:BOX37_RS13600
uniprot id: A0A1J0VRW9
names: Subcellular Location Annotation
messages: Membrane

2213200:BOX37 RS08860
gene id: 2213200:BOX37_RS08860
uniprot id: A0A1J0VPT4
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

2213200:BOX37 RS31475
gene id: 2213200:BOX37_RS31475
uniprot id: A0A1J0VZU2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

2213200:BOX37 RS12035
gene id: 2213200:BOX37_RS12035
uniprot id: A0A1J0VRA1
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

2213200:BOX37 RS31485
gene id: 2213200:BOX37_RS31485
uniprot id: A0A1J0W012
names: Subcellular Location Annotation
messages: Membrane

2213200:BOX37 RS29805
gene id: 2213200:BOX37_RS29805
uniprot id: A0A1J0VZE1
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

2213200:BOX37 RS25645
gene id: 2213200:BOX37_RS25645
uniprot id: A0A1J0W382
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NucS endonuclease family.
messages: Cleaves both 3' and 5' ssDNA extremities of branched DNA structures.
messages: Cytoplasm

2213200:BOX37 RS25865
gene id: 2213200:BOX37_RS25865
uniprot id: A0A1J0VXB2
names: Similarity
messages: Belongs to the LOG family.

2213200:BOX37 RS16755
gene id: 2213200:BOX37_RS16755
uniprot id: A0A1J0VTA8
names: Function
names: Similarity
messages: APS kinase catalyzes the synthesis of activated sulfate.
messages: Belongs to the APS kinase family.
messages: Catalyzes the synthesis of activated sulfate.
messages: In the C-terminal section; belongs to the APS kinase family.
messages: In the N-terminal section; belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.

2213200:BOX37 RS17075
gene id: 2213200:BOX37_RS17075
uniprot id: A0A1J0VTS2
names: Subunit
messages: Heterodimer of an alpha and a beta chain.

2213200:BOX37 RS01075
gene id: 2213200:BOX37_RS01075
uniprot id: A0A1J0W128
names: Similarity
messages: Belongs to the Vsr family.

2213200:BOX37 RS19480
gene id: 2213200:BOX37_RS19480
uniprot id: A0A1J0VUK4
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

2213200:BOX37 RS13350
gene id: 2213200:BOX37_RS13350
uniprot id: A0A1J0VS07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2213200:BOX37 RS10535
gene id: 2213200:BOX37_RS10535
uniprot id: A0A1J0W1J9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

2213200:BOX37 RS00495
gene id: 2213200:BOX37_RS00495
uniprot id: A0A1J0VL01
names: Similarity
messages: Belongs to the EspG family.

2213200:BOX37 RS21175
gene id: 2213200:BOX37_RS21175
uniprot id: A0A1J0VVC9
names: Similarity
messages: Belongs to the PspA/IM30 family.

2213200:BOX37 RS21885
gene id: 2213200:BOX37_RS21885
uniprot id: A0A1J0VVR6
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

2213200:BOX37 RS29070
gene id: 2213200:BOX37_RS29070
uniprot id: A0A1J0VZ82
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

2213200:BOX37 RS22005
gene id: 2213200:BOX37_RS22005
uniprot id: A0A1J0VVL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0719 family.
messages: Membrane

2213200:BOX37 RS20280
gene id: 2213200:BOX37_RS20280
uniprot id: A0A1J0W2K0
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

2213200:BOX37 RS01110
gene id: 2213200:BOX37_RS01110
uniprot id: A0A1J0W0S4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

2213200:BOX37 RS05380
gene id: 2213200:BOX37_RS05380
uniprot id: A0A1J0VN88
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

2213200:BOX37 RS29935
gene id: 2213200:BOX37_RS29935
uniprot id: A0A1J0W3H8
names: Caution
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
messages: Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).
messages: Could possibly oxidize fatty acids using specific components.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2213200:BOX37 RS30140
gene id: 2213200:BOX37_RS30140
uniprot id: A0A1J0VZ69
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

2213200:BOX37 RS32655
gene id: 2213200:BOX37_RS32655
uniprot id: A0A1J0W0L3
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

2213200:BOX37 RS21840
gene id: 2213200:BOX37_RS21840
uniprot id: A0A1J0VVK3
names: Subcellular Location Annotation
messages: Membrane

2213200:BOX37 RS25930
gene id: 2213200:BOX37_RS25930
uniprot id: A0A1J0VXD9
names: Function
names: Similarity
messages: Catalyzes the radical-mediated synthesis of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (FO) from 5-amino-6-(D-ribitylamino)uracil and L-tyrosine.
messages: In the C-terminal section; belongs to the radical SAM superfamily. CofH family.
messages: In the N-terminal section; belongs to the radical SAM superfamily. CofG family.

2213200:BOX37 RS01280
gene id: 2213200:BOX37_RS01280
uniprot id: A0A1J0VLC9
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: Could possibly oxidize fatty acids using specific components.
messages: In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.

2213200:BOX37 RS25965
gene id: 2213200:BOX37_RS25965
uniprot id: A0A1J0VXC7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the MshB deacetylase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deacetylation of 1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway.

2213200:BOX37 RS04365
gene id: 2213200:BOX37_RS04365
uniprot id: A0A1J0VMQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaD and TsaB. TsaE seems to play an indirect role in the t(6)A biosynthesis pathway, possibly in regulating the core enzymatic function of TsaD.

2213200:BOX37 RS09545
gene id: 2213200:BOX37_RS09545
uniprot id: A0A1J0VQ62
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

2213200:BOX37 RS29115
gene id: 2213200:BOX37_RS29115
uniprot id: A0A1J0VZ89
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

2213200:BOX37 RS26910
gene id: 2213200:BOX37_RS26910
uniprot id: A0A1J0VXS5
names: Similarity
messages: Belongs to the peptidase S1 family.

2213200:BOX37 RS21275
gene id: 2213200:BOX37_RS21275
uniprot id: A0A1J0VVF4
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

2213200:BOX37 RS02460
gene id: 2213200:BOX37_RS02460
uniprot id: A0A1J0VLV8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

2213200:BOX37 RS31970
gene id: 2213200:BOX37_RS31970
uniprot id: A0A1J0W030
names: Similarity
messages: Belongs to the universal stress protein A family.

2213200:BOX37 RS16070
gene id: 2213200:BOX37_RS16070
uniprot id: A0A1J0VT00
names: Similarity
messages: Belongs to the eukaryotic/archaeal PrmC-related family.

2213200:BOX37 RS06925
gene id: 2213200:BOX37_RS06925
uniprot id: A0A1J0VNW4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

2213200:BOX37 RS30990
gene id: 2213200:BOX37_RS30990
uniprot id: A0A1J0VZP6
names: Similarity
messages: Belongs to the peptidase S33 family.

2213200:BOX37 RS04285
gene id: 2213200:BOX37_RS04285
uniprot id: A0A1J0VMR7
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

2213200:BOX37 RS20845
gene id: 2213200:BOX37_RS20845
uniprot id: A0A1J0VVG4
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

2213200:BOX37 RS27950
gene id: 2213200:BOX37_RS27950
uniprot id: A0A1J0VYN3
names: Similarity
messages: Belongs to the CsoR family.

2213200:BOX37 RS31140
gene id: 2213200:BOX37_RS31140
uniprot id: A0A1J0VZS5
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

2213200:BOX37 RS31040
gene id: 2213200:BOX37_RS31040
uniprot id: A0A1J0VZQ7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

2213200:BOX37 RS27505
gene id: 2213200:BOX37_RS27505
uniprot id: A0A1J0VYA0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

2213200:BOX37 RS23335
gene id: 2213200:BOX37_RS23335
uniprot id: A0A1J0VWA2
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

2213200:BOX37 RS14335
gene id: 2213200:BOX37_RS14335
uniprot id: A0A1J0VS79
names: Similarity
messages: Belongs to the NtaA/SnaA/DszA monooxygenase family.

2213200:BOX37 RS30800
gene id: 2213200:BOX37_RS30800
uniprot id: A0A1J0VZV4
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain.

2213200:BOX37 RS25810
gene id: 2213200:BOX37_RS25810
uniprot id: A0A1J0VXG6
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

2213200:BOX37 RS29625
gene id: 2213200:BOX37_RS29625
uniprot id: A0A1J0VZ79
names: Cofactor
names: Similarity
messages: Belongs to the 4HPPD family.
messages: Binds 1 Fe cation per subunit.

2213200:BOX37 RS22240
gene id: 2213200:BOX37_RS22240
uniprot id: A0A1J0VVX1
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

2213200:BOX37 RS05320
gene id: 2213200:BOX37_RS05320
uniprot id: A0A1J0VN87
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

2213200:BOX37 RS18505
gene id: 2213200:BOX37_RS18505
uniprot id: A0A1J0VU90
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

2213200:BOX37 RS11525
gene id: 2213200:BOX37_RS11525
uniprot id: A0A1J0VR13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA-PH family.
messages: Cytoplasm

2213200:BOX37 RS23350
gene id: 2213200:BOX37_RS23350
uniprot id: A0A1J0VWK8
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family. MbtB subfamily.

2213200:BOX37 RS25235
gene id: 2213200:BOX37_RS25235
uniprot id: A0A1J0VXF4
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

2213200:BOX37 RS27870
gene id: 2213200:BOX37_RS27870
uniprot id: A0A1J0VYG6
names: Similarity
messages: Belongs to the cytochrome P450 family.

2213200:BOX37 RS05420
gene id: 2213200:BOX37_RS05420
uniprot id: A0A1J0VNA4
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

2213200:BOX37 RS20440
gene id: 2213200:BOX37_RS20440
uniprot id: A0A1J0VUZ7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

2213200:BOX37 RS17795
gene id: 2213200:BOX37_RS17795
uniprot id: A0A1J0VTU5
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

2213200:BOX37 RS25085
gene id: 2213200:BOX37_RS25085
uniprot id: A0A1J0VX09
names: Subcellular Location Annotation
messages: Cytoplasm

2213200:BOX37 RS06765
gene id: 2213200:BOX37_RS06765
uniprot id: A0A1J0VNW6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

2213200:BOX37 RS15530
gene id: 2213200:BOX37_RS15530
uniprot id: A0A1J0VSR5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

2213200:BOX37 RS26140
gene id: 2213200:BOX37_RS26140
uniprot id: A0A1J0VXW1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

2213200:BOX37 RS04570
gene id: 2213200:BOX37_RS04570
uniprot id: A0A1J0VMW6
names: Activity Regulation
names: Caution
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2213200:BOX37 RS27550
gene id: 2213200:BOX37_RS27550
uniprot id: A0A1J0VYA6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

2213200:BOX37 RS29040
gene id: 2213200:BOX37_RS29040
uniprot id: A0A1J0VZ09
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

2213200:BOX37 RS04705
gene id: 2213200:BOX37_RS04705
uniprot id: A0A1J0VMX6
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.

2213200:BOX37 RS27150
gene id: 2213200:BOX37_RS27150
uniprot id: A0A1J0VXZ6
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

2213200:BOX37 RS31230
gene id: 2213200:BOX37_RS31230
uniprot id: A0A1J0VZQ4
names: Subcellular Location Annotation
messages: Membrane

2213200:BOX37 RS35195
gene id: 2213200:BOX37_RS35195
uniprot id: A0A1J0VQ16
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

2213200:BOX37 RS10240
gene id: 2213200:BOX37_RS10240
uniprot id: A0A1J0VQH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

2213200:BOX37 RS13575
gene id: 2213200:BOX37_RS13575
uniprot id: A0A1J0VRY7
names: Subcellular Location Annotation
messages: Membrane

2213200:BOX37 RS10280
gene id: 2213200:BOX37_RS10280
uniprot id: A0A1J0VQH2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IPP isomerase type 1 family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium ion binds only when substrate is bound.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).
messages: Cytoplasm

2213200:BOX37 RS18275
gene id: 2213200:BOX37_RS18275
uniprot id: A0A1J0W2F9
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

2213200:BOX37 RS17605
gene id: 2213200:BOX37_RS17605
uniprot id: A0A1J0VTQ1
names: Subcellular Location Annotation
messages: Membrane

2213200:BOX37 RS23840
gene id: 2213200:BOX37_RS23840
uniprot id: A0A1J0VWK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. TCR/Tet family.
messages: Membrane

2213200:BOX37 RS29055
gene id: 2213200:BOX37_RS29055
uniprot id: A0A1J0VYU5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

2213200:BOX37 RS17640
gene id: 2213200:BOX37_RS17640
uniprot id: A0A1J0VTS0
names: Similarity
messages: Belongs to the CFA/CMAS family.

2213200:BOX37 RS32545
gene id: 2213200:BOX37_RS32545
uniprot id: A0A1J0W0E2
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

2213200:BOX37 RS09170
gene id: 2213200:BOX37_RS09170
uniprot id: A0A1J0VPZ7
names: Subcellular Location Annotation
messages: Membrane

2213200:BOX37 RS14565
gene id: 2213200:BOX37_RS14565
uniprot id: A0A1J0VSB1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

2213200:BOX37 RS29720
gene id: 2213200:BOX37_RS29720
uniprot id: A0A1J0VZ08
names: Similarity
messages: Belongs to the pirin family.

2213200:BOX37 RS26975
gene id: 2213200:BOX37_RS26975
uniprot id: A0A1J0VY20
names: Similarity
messages: Belongs to the EccD/Snm4 family.

2213200:BOX37 RS10420
gene id: 2213200:BOX37_RS10420
uniprot id: A0A1J0VQI1
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2213200:BOX37 RS04055
gene id: 2213200:BOX37_RS04055
uniprot id: A0A1J0VMN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EccB family.
messages: Membrane

2213200:BOX37 RS21310
gene id: 2213200:BOX37_RS21310
uniprot id: A0A1J0VVC3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

2213200:BOX37 RS02980
gene id: 2213200:BOX37_RS02980
uniprot id: A0A1J0VM58
names: Similarity
messages: Belongs to the DyP-type peroxidase family.

2213200:BOX37 RS10055
gene id: 2213200:BOX37_RS10055
uniprot id: A0A1J0VQJ4
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

2213200:BOX37 RS05010
gene id: 2213200:BOX37_RS05010
uniprot id: A0A1J0VN28
names: Function
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

2213200:BOX37 RS15985
gene id: 2213200:BOX37_RS15985
uniprot id: A0A1J0VT25
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

2213200:BOX37 RS23985
gene id: 2213200:BOX37_RS23985
uniprot id: A0A1J0VWN4
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

2213200:BOX37 RS10650
gene id: 2213200:BOX37_RS10650
uniprot id: A0A1J0VQM9
names: Subcellular Location Annotation
messages: Membrane

2213200:BOX37 RS09230
gene id: 2213200:BOX37_RS09230
uniprot id: A0A1J0W1F1
names: Similarity
messages: Belongs to the peptidase C40 family.

2213200:BOX37 RS23240
gene id: 2213200:BOX37_RS23240
uniprot id: A0A1J0VW63
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Heterodimer of an alpha and a beta subunit.
messages: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

2213200:BOX37 RS27025
gene id: 2213200:BOX37_RS27025
uniprot id: A0A1J0VY01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CbxX/CfxQ family.
messages: Cytoplasm

2213200:BOX37 RS15610
gene id: 2213200:BOX37_RS15610
uniprot id: A0A1J0VSU4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

2213200:BOX37 RS06305
gene id: 2213200:BOX37_RS06305
uniprot id: A0A1J0VNL9
names: Similarity
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

2213200:BOX37 RS23845
gene id: 2213200:BOX37_RS23845
uniprot id: A0A1J0W313
names: Similarity
messages: Belongs to the phosphohexose mutase family.

2213200:BOX37 RS08015
gene id: 2213200:BOX37_RS08015
uniprot id: A0A1J0VPE8
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

2213200:BOX37 RS11840
gene id: 2213200:BOX37_RS11840
uniprot id: A0A1J0VR36
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sirtuin family. Class II subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form.

2213200:BOX37 RS14880
gene id: 2213200:BOX37_RS14880
uniprot id: A0A1J0VSJ1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

2213200:BOX37 RS09335
gene id: 2213200:BOX37_RS09335
uniprot id: A0A1J0VQ20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

2213200:BOX37 RS19305
gene id: 2213200:BOX37_RS19305
uniprot id: A0A1J0VUK9
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

2213200:BOX37 RS06795
gene id: 2213200:BOX37_RS06795
uniprot id: A0A1J0VNW1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

2213200:BOX37 RS17890
gene id: 2213200:BOX37_RS17890
uniprot id: A0A1J0VTY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2213200:BOX37 RS22620
gene id: 2213200:BOX37_RS22620
uniprot id: A0A1J0VW90
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

2213200:BOX37 RS31310
gene id: 2213200:BOX37_RS31310
uniprot id: A0A1J0VZU9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Cell membrane
messages: Membrane

2213200:BOX37 RS27905
gene id: 2213200:BOX37_RS27905
uniprot id: A0A1J0VYM5
names: Subcellular Location Annotation
messages: Membrane

2213200:BOX37 RS14745
gene id: 2213200:BOX37_RS14745
uniprot id: A0A1J0VSE6
names: Similarity
messages: Belongs to the Fur family.

2213200:BOX37 RS23850
gene id: 2213200:BOX37_RS23850
uniprot id: A0A1J0VWL4
names: Subcellular Location Annotation
messages: Membrane

2213200:BOX37 RS06625
gene id: 2213200:BOX37_RS06625
uniprot id: A0A1J0VNU4
names: Similarity
messages: Belongs to the YciI family.

2213200:BOX37 RS02025
gene id: 2213200:BOX37_RS02025
uniprot id: A0A1J0VLQ7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2213200:BOX37 RS23095
gene id: 2213200:BOX37_RS23095
uniprot id: A0A1J0VW42
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

2213200:BOX37 RS18315
gene id: 2213200:BOX37_RS18315
uniprot id: A0A1J0VU09
names: Subcellular Location Annotation
messages: Membrane

2213200:BOX37 RS29145
gene id: 2213200:BOX37_RS29145
uniprot id: A0A1J0VYV1
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

2213200:BOX37 RS24795
gene id: 2213200:BOX37_RS24795
uniprot id: A0A1J0VWW1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

2213200:BOX37 RS15280
gene id: 2213200:BOX37_RS15280
uniprot id: A0A1J0VSQ6
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

2213200:BOX37 RS18800
gene id: 2213200:BOX37_RS18800
uniprot id: A0A1J0W2G7
names: Similarity
messages: Belongs to the cytochrome P450 family.

2213200:BOX37 RS25825
gene id: 2213200:BOX37_RS25825
uniprot id: A0A1J0VXI0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatB family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

2213200:BOX37 RS02900
gene id: 2213200:BOX37_RS02900
uniprot id: A0A1J0VM49
names: Cofactor
names: Similarity
messages: Belongs to the fatty acid desaturase type 2 family.
messages: Binds 2 iron ions per subunit.

2213200:BOX37 RS04060
gene id: 2213200:BOX37_RS04060
uniprot id: A0A1J0VMP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CbxX/CfxQ family.
messages: Cytoplasm

2213200:BOX37 RS32260
gene id: 2213200:BOX37_RS32260
uniprot id: A0A1J0W0F5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

2213200:BOX37 RS32725
gene id: 2213200:BOX37_RS32725
uniprot id: A0A1J0W0T6
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

2213200:BOX37 RS16495
gene id: 2213200:BOX37_RS16495
uniprot id: A0A1J0VTA5
names: Subcellular Location Annotation
messages: Membrane

2213200:BOX37 RS12010
gene id: 2213200:BOX37_RS12010
uniprot id: A0A1J0VR80
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

2213200:BOX37 RS18710
gene id: 2213200:BOX37_RS18710
uniprot id: A0A1J0VUK0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

2213200:BOX37 RS28610
gene id: 2213200:BOX37_RS28610
uniprot id: A0A1J0VYI6
names: Subcellular Location Annotation
messages: Cytoplasm

2213200:BOX37 RS31025
gene id: 2213200:BOX37_RS31025
uniprot id: A0A1J0W000
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

2213200:BOX37 RS26065
gene id: 2213200:BOX37_RS26065
uniprot id: A0A1J0W346
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

2213200:BOX37 RS11675
gene id: 2213200:BOX37_RS11675
uniprot id: A0A1J0VR37
names: Function
messages: TetR is the repressor of the tetracycline resistance element; its N-terminal region forms a helix-turn-helix structure and binds DNA. Binding of tetracycline to TetR reduces the repressor affinity for the tetracycline resistance gene (tetA) promoter operator sites.

2213200:BOX37 RS09385
gene id: 2213200:BOX37_RS09385
uniprot id: A0A1J0VQ28
names: Function
names: Similarity
messages: Belongs to the serine/threonine dehydratase family.
messages: Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.

2213200:BOX37 RS11080
gene id: 2213200:BOX37_RS11080
uniprot id: A0A1J0VQQ7
names: Similarity
messages: Belongs to the CFA/CMAS family.

2213200:BOX37 RS20520
gene id: 2213200:BOX37_RS20520
uniprot id: A0A1J0VV35
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2213200:BOX37 RS15095
gene id: 2213200:BOX37_RS15095
uniprot id: A0A1J0VSL2
names: Similarity
messages: Belongs to the YciI family.

2213200:BOX37 RS25710
gene id: 2213200:BOX37_RS25710
uniprot id: A0A1J0VXB0
names: Similarity
messages: Belongs to the peptidase S58 family.

2213200:BOX37 RS06210
gene id: 2213200:BOX37_RS06210
uniprot id: A0A1J0VNM7
names: Similarity
messages: Belongs to the pirin family.

2213200:BOX37 RS10720
gene id: 2213200:BOX37_RS10720
uniprot id: A0A1J0VQK4
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. HypB/HupM subfamily.

2213200:BOX37 RS25405
gene id: 2213200:BOX37_RS25405
uniprot id: A0A1J0VX53
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

2213200:BOX37 RS23585
gene id: 2213200:BOX37_RS23585
uniprot id: A0A1J0VWH5
names: Subcellular Location Annotation
messages: Membrane

2213200:BOX37 RS29560
gene id: 2213200:BOX37_RS29560
uniprot id: A0A1J0VZ83
names: Subcellular Location Annotation
messages: Membrane

2213200:BOX37 RS12340
gene id: 2213200:BOX37_RS12340
uniprot id: A0A1J0VRF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CbxX/CfxQ family.
messages: Cytoplasm

2213200:BOX37 RS29795
gene id: 2213200:BOX37_RS29795
uniprot id: A0A1J0VZJ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

2213200:BOX37 RS26550
gene id: 2213200:BOX37_RS26550
uniprot id: A0A1J0W362
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Membrane

2213200:BOX37 RS04500
gene id: 2213200:BOX37_RS04500
uniprot id: A0A1J0VMW5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

2213200:BOX37 RS31115
gene id: 2213200:BOX37_RS31115
uniprot id: A0A1J0VZX6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the CobB/CobQ family.
messages: Involved in acetate metabolism.
messages: The N-terminal region seems to be important for proper quaternary structure. The C-terminal region contains the substrate-binding site.

2213200:BOX37 RS11070
gene id: 2213200:BOX37_RS11070
uniprot id: A0A1J0VQU5
names: Subcellular Location Annotation
messages: Membrane

2213200:BOX37 RS10155
gene id: 2213200:BOX37_RS10155
uniprot id: A0A1J0VQB6
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

2213200:BOX37 RS23390
gene id: 2213200:BOX37_RS23390
uniprot id: A0A1J0VWC7
names: Similarity
messages: Belongs to the AB hydrolase superfamily. Lipase family.

2213200:BOX37 RS03010
gene id: 2213200:BOX37_RS03010
uniprot id: A0A1J0VM38
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

2213200:BOX37 RS00085
gene id: 2213200:BOX37_RS00085
uniprot id: A0A1J0VKS2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrgA family.
messages: Cell membrane
messages: Involved in cell division.

2213200:BOX37 RS09175
gene id: 2213200:BOX37_RS09175
uniprot id: A0A1J0VQ55
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2213200:BOX37 RS16685
gene id: 2213200:BOX37_RS16685
uniprot id: A0A1J0VTB0
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

2213200:BOX37 RS29470
gene id: 2213200:BOX37_RS29470
uniprot id: A0A1J0VZ59
names: Similarity
messages: Belongs to the catalase family.

2213200:BOX37 RS15900
gene id: 2213200:BOX37_RS15900
uniprot id: A0A1J0VSY9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

2213200:BOX37 RS06370
gene id: 2213200:BOX37_RS06370
uniprot id: A0A1J0W1D1
names: Similarity
messages: Belongs to the iron/ascorbate-dependent oxidoreductase family.

2213200:BOX37 RS20020
gene id: 2213200:BOX37_RS20020
uniprot id: A0A1J0W2F8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

2213200:BOX37 RS23495
gene id: 2213200:BOX37_RS23495
uniprot id: A0A1J0VWE4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
messages: Homodimer.

2213200:BOX37 RS04585
gene id: 2213200:BOX37_RS04585
uniprot id: A0A1J0VMX5
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

2213200:BOX37 RS22250
gene id: 2213200:BOX37_RS22250
uniprot id: A0A1J0W2T0
names: Subcellular Location Annotation
messages: Cytoplasm

2213200:BOX37 RS08855
gene id: 2213200:BOX37_RS08855
uniprot id: A0A1J0VPU0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

2213200:BOX37 RS01815
gene id: 2213200:BOX37_RS01815
uniprot id: A0A1J0VLJ7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2213200:BOX37 RS29440
gene id: 2213200:BOX37_RS29440
uniprot id: A0A1J0VYW8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

2213200:BOX37 RS09195
gene id: 2213200:BOX37_RS09195
uniprot id: A0A1J0VPY6
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

2213200:BOX37 RS07555
gene id: 2213200:BOX37_RS07555
uniprot id: A0A1J0VP90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

2213200:BOX37 RS15925
gene id: 2213200:BOX37_RS15925
uniprot id: A0A1J0VT15
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family. Carboxylic acid reductase subfamily.
messages: Binds 1 phosphopantetheine covalently.
messages: Catalyzes the ATP- and NADPH-dependent reduction of carboxylic acids to the corresponding aldehydes.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The N-terminal domain likely catalyzes substrate activation by formation of an initial acyl-AMP intermediate, the central region contains the phosphopantetheine attachment site, and the C-terminal domain catalyzes the reduction by NADPH of the intermediate thioester formed from the attack of the phosphopantetheine thiol at the carbonyl carbon of acyl-AMP.

2213200:BOX37 RS08605
gene id: 2213200:BOX37_RS08605
uniprot id: A0A1J0W1C8
names: Similarity
messages: Belongs to the calycin superfamily. Lipocalin family.

2213200:BOX37 RS08770
gene id: 2213200:BOX37_RS08770
uniprot id: A0A1J0VPS0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

2213200:BOX37 RS05360
gene id: 2213200:BOX37_RS05360
uniprot id: A0A1J0VN63
names: Subcellular Location Annotation
messages: Membrane

2213200:BOX37 RS20910
gene id: 2213200:BOX37_RS20910
uniprot id: A0A1J0VV49
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

2213200:BOX37 RS21465
gene id: 2213200:BOX37_RS21465
uniprot id: A0A1J0VVH6
names: Subcellular Location Annotation
messages: Membrane

2213200:BOX37 RS05465
gene id: 2213200:BOX37_RS05465
uniprot id: A0A1J0VN84
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

2213200:BOX37 RS17385
gene id: 2213200:BOX37_RS17385
uniprot id: A0A1J0VTL0
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

2213200:BOX37 RS21970
gene id: 2213200:BOX37_RS21970
uniprot id: A0A1J0VVT6
names: Activity Regulation
names: Caution
names: Domain
names: Function
names: Similarity
messages: Belongs to the GlnD family.
messages: Has four distinct domains: an N-terminal nucleotidyltransferase (NT) domain responsible for UTase activity, a central HD domain that encodes UR activity, and two C-terminal ACT domains that seem to have a role in glutamine sensing.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism.
messages: Uridylyltransferase (UTase) activity is inhibited by glutamine, while glutamine activates uridylyl-removing (UR) activity.

2213200:BOX37 RS21315
gene id: 2213200:BOX37_RS21315
uniprot id: A0A1J0VVG2
names: Similarity
messages: Belongs to the ribF family.

2213200:BOX37 RS04270
gene id: 2213200:BOX37_RS04270
uniprot id: A0A1J0VMP6
names: Subcellular Location Annotation
messages: Membrane

2213200:BOX37 RS27105
gene id: 2213200:BOX37_RS27105
uniprot id: A0A1J0VXY8
names: Similarity
messages: Belongs to the mycobacterial PPE family.

2213200:BOX37 RS08100
gene id: 2213200:BOX37_RS08100
uniprot id: A0A1J0VPI3
names: Function
names: Similarity
messages: Belongs to the GlnE family.
messages: Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell.

2213200:BOX37 RS14705
gene id: 2213200:BOX37_RS14705
uniprot id: A0A1J0VSE0
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

2213200:BOX37 RS23740
gene id: 2213200:BOX37_RS23740
uniprot id: A0A1J0VWG5
names: Similarity
messages: Belongs to the adenylyl cyclase class-3 family.

2213200:BOX37 RS09205
gene id: 2213200:BOX37_RS09205
uniprot id: A0A1J0VPY4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SepF family.
messages: Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
messages: Cytoplasm
messages: Homodimer. Interacts with FtsZ.

2213200:BOX37 RS20960
gene id: 2213200:BOX37_RS20960
uniprot id: A0A1J0VVI0
names: Function
names: Similarity
names: Subunit
messages: Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity.
messages: Belongs to the AhpD family.
messages: Homotrimer.

2213200:BOX37 RS26330
gene id: 2213200:BOX37_RS26330
uniprot id: A0A1J0VXZ1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial microcompartment
messages: Belongs to the EutC family.
messages: Binds between the large and small subunits.
messages: Catalyzes the deamination of various vicinal amino-alcohols to oxo compounds. Allows this organism to utilize ethanolamine as the sole source of nitrogen and carbon in the presence of external vitamin B12.
messages: The basic unit is a heterodimer which dimerizes to form tetramers. The heterotetramers trimerize; 6 large subunits form a core ring with 6 small subunits projecting outwards.

2213200:BOX37 RS06790
gene id: 2213200:BOX37_RS06790
uniprot id: A0A1J0VNW8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

2213200:BOX37 RS12260
gene id: 2213200:BOX37_RS12260
uniprot id: A0A1J0VRA4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

2213200:BOX37 RS13275
gene id: 2213200:BOX37_RS13275
uniprot id: A0A1J0VRS7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

2213200:BOX37 RS32030
gene id: 2213200:BOX37_RS32030
uniprot id: A0A1J0W038
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

2213200:BOX37 RS30185
gene id: 2213200:BOX37_RS30185
uniprot id: A0A1J0VZP9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

2213200:BOX37 RS26790
gene id: 2213200:BOX37_RS26790
uniprot id: A0A1J0VXW2
names: Subcellular Location Annotation
messages: Membrane

2213200:BOX37 RS05715
gene id: 2213200:BOX37_RS05715
uniprot id: A0A1J0VNC1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

2213200:BOX37 RS22100
gene id: 2213200:BOX37_RS22100
uniprot id: A0A1J0VW03
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 independent methionine synthase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.

2213200:BOX37 RS32530
gene id: 2213200:BOX37_RS32530
uniprot id: A0A1J0W0B4
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

2213200:BOX37 RS16235
gene id: 2213200:BOX37_RS16235
uniprot id: A0A1J0VT62
names: Subcellular Location Annotation
messages: Membrane

2213200:BOX37 RS09135
gene id: 2213200:BOX37_RS09135
uniprot id: A0A1J0VQ44
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

2213200:BOX37 RS15700
gene id: 2213200:BOX37_RS15700
uniprot id: A0A1J0VSU9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

2213200:BOX37 RS10145
gene id: 2213200:BOX37_RS10145
uniprot id: A0A1J0VQE5
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

2213200:BOX37 RS22290
gene id: 2213200:BOX37_RS22290
uniprot id: A0A1J0VVY0
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

2213200:BOX37 RS04830
gene id: 2213200:BOX37_RS04830
uniprot id: A0A1J0VMX9
names: Activity Regulation
names: Caution
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2213200:BOX37 RS35575
gene id: 2213200:BOX37_RS35575
uniprot id: A0A1J0VY39
names: Subcellular Location Annotation
messages: Membrane

2213200:BOX37 RS22625
gene id: 2213200:BOX37_RS22625
uniprot id: A0A1J0VVW4
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

2213200:BOX37 RS16460
gene id: 2213200:BOX37_RS16460
uniprot id: A0A1J0VT75
names: Similarity
messages: Belongs to the CFA/CMAS family.

2213200:BOX37 RS00075
gene id: 2213200:BOX37_RS00075
uniprot id: A0A1J0VKU9
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

2213200:BOX37 RS21230
gene id: 2213200:BOX37_RS21230
uniprot id: A0A1J0VVD3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

2213200:BOX37 RS25790
gene id: 2213200:BOX37_RS25790
uniprot id: A0A1J0VXB1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
messages: Monomer.

2213200:BOX37 RS27585
gene id: 2213200:BOX37_RS27585
uniprot id: A0A1J0VY60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arginine deiminase family.
messages: Cytoplasm

2213200:BOX37 RS03880
gene id: 2213200:BOX37_RS03880
uniprot id: A0A1J0VMI0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

2213200:BOX37 RS10260
gene id: 2213200:BOX37_RS10260
uniprot id: A0A1J0W1J8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2213200:BOX37 RS30565
gene id: 2213200:BOX37_RS30565
uniprot id: A0A1J0VZE0
names: Function
names: Similarity
messages: Belongs to the uricase family.
messages: Catalyzes the oxidation of uric acid to 5-hydroxyisourate, which is further processed to form (S)-allantoin.

2213200:BOX37 RS30600
gene id: 2213200:BOX37_RS30600
uniprot id: A0A1J0VZW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2213200:BOX37 RS16895
gene id: 2213200:BOX37_RS16895
uniprot id: A0A1J0W270
names: Similarity
messages: Belongs to the AB hydrolase superfamily. Lipase family.

2213200:BOX37 RS02005
gene id: 2213200:BOX37_RS02005
uniprot id: A0A1J0VLQ4
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

2213200:BOX37 RS03055
gene id: 2213200:BOX37_RS03055
uniprot id: A0A1J0VM47
names: Similarity
messages: Belongs to the helicase family. RAD25/XPB subfamily.

2213200:BOX37 RS09840
gene id: 2213200:BOX37_RS09840
uniprot id: A0A1J0VQ82
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2213200:BOX37 RS11015
gene id: 2213200:BOX37_RS11015
uniprot id: A0A1J0VQS2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2213200:BOX37 RS08615
gene id: 2213200:BOX37_RS08615
uniprot id: A0A1J0VPW4
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

2213200:BOX37 RS27005
gene id: 2213200:BOX37_RS27005
uniprot id: A0A1J0VY42
names: Similarity
messages: Belongs to the mycobacterial PPE family.

2213200:BOX37 RS21340
gene id: 2213200:BOX37_RS21340
uniprot id: A0A1J0VVI3
names: Subcellular Location Annotation
messages: Membrane

2213200:BOX37 RS01845
gene id: 2213200:BOX37_RS01845
uniprot id: A0A1J0VLL6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

2213200:BOX37 RS17715
gene id: 2213200:BOX37_RS17715
uniprot id: A0A1J0VU28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

2213200:BOX37 RS05350
gene id: 2213200:BOX37_RS05350
uniprot id: A0A1J0W132
names: Caution
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

2213200:BOX37 RS11845
gene id: 2213200:BOX37_RS11845
uniprot id: A0A1J0VR71
names: Subcellular Location Annotation
messages: Membrane

2213200:BOX37 RS09680
gene id: 2213200:BOX37_RS09680
uniprot id: A0A1J0VQ79
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

2213200:BOX37 RS30850
gene id: 2213200:BOX37_RS30850
uniprot id: A0A1J0VZR3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

2213200:BOX37 RS18985
gene id: 2213200:BOX37_RS18985
uniprot id: A0A1J0VUE1
names: Subcellular Location Annotation
messages: Membrane

2213200:BOX37 RS05605
gene id: 2213200:BOX37_RS05605
uniprot id: A0A1J0VND1
names: Similarity
messages: Belongs to the thiolase-like superfamily. FabH family.

2213200:BOX37 RS10995
gene id: 2213200:BOX37_RS10995
uniprot id: A0A1J0VQP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2213200:BOX37 RS25230
gene id: 2213200:BOX37_RS25230
uniprot id: A0A1J0VX63
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

2213200:BOX37 RS27440
gene id: 2213200:BOX37_RS27440
uniprot id: A0A1J0VYF8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2213200:BOX37 RS03600
gene id: 2213200:BOX37_RS03600
uniprot id: A0A1J0VMD5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

2213200:BOX37 RS02765
gene id: 2213200:BOX37_RS02765
uniprot id: A0A1J0VM21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

2213200:BOX37 RS02285
gene id: 2213200:BOX37_RS02285
uniprot id: A0A1J0W188
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

2213200:BOX37 RS25760
gene id: 2213200:BOX37_RS25760
uniprot id: A0A1J0VXG5
names: Subcellular Location Annotation
messages: Membrane

2213200:BOX37 RS20555
gene id: 2213200:BOX37_RS20555
uniprot id: A0A1J0VV15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 87 family.
messages: Membrane

2213200:BOX37 RS02855
gene id: 2213200:BOX37_RS02855
uniprot id: A0A1J0VM39
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetyltransferase family. MshD subfamily.
messages: Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

2213200:BOX37 RS12020
gene id: 2213200:BOX37_RS12020
uniprot id: A0A1J0VR86
names: Similarity
messages: Belongs to the ComB family.

2213200:BOX37 RS24410
gene id: 2213200:BOX37_RS24410
uniprot id: A0A1J0VWU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

2213200:BOX37 RS14505
gene id: 2213200:BOX37_RS14505
uniprot id: A0A1J0VSC1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

2213200:BOX37 RS17365
gene id: 2213200:BOX37_RS17365
uniprot id: A0A1J0VTN9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the malate synthase family. GlcB subfamily.
messages: Cytoplasm
messages: Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

2213200:BOX37 RS15410
gene id: 2213200:BOX37_RS15410
uniprot id: A0A1J0VT10
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

2213200:BOX37 RS21190
gene id: 2213200:BOX37_RS21190
uniprot id: A0A1J0VV88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

2213200:BOX37 RS21880
gene id: 2213200:BOX37_RS21880
uniprot id: A0A1J0VVR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

2213200:BOX37 RS19760
gene id: 2213200:BOX37_RS19760
uniprot id: A0A1J0VUT5
names: Similarity
messages: Belongs to the peptidase C40 family.

2213200:BOX37 RS24535
gene id: 2213200:BOX37_RS24535
uniprot id: A0A1J0W2Z8
names: Subcellular Location Annotation
messages: Membrane

2213200:BOX37 RS06780
gene id: 2213200:BOX37_RS06780
uniprot id: A0A1J0VNU0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

2213200:BOX37 RS18925
gene id: 2213200:BOX37_RS18925
uniprot id: A0A1J0VUN2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

2213200:BOX37 RS16875
gene id: 2213200:BOX37_RS16875
uniprot id: A0A1J0VTE4
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

2213200:BOX37 RS09910
gene id: 2213200:BOX37_RS09910
uniprot id: A0A1J0VQ77
names: Similarity
messages: Belongs to the universal stress protein A family.

2213200:BOX37 RS05575
gene id: 2213200:BOX37_RS05575
uniprot id: A0A1J0VNC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

2213200:BOX37 RS18675
gene id: 2213200:BOX37_RS18675
uniprot id: A0A1J0VUA5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

2213200:BOX37 RS17460
gene id: 2213200:BOX37_RS17460
uniprot id: A0A1J0VTP0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2213200:BOX37 RS25670
gene id: 2213200:BOX37_RS25670
uniprot id: A0A1J0VXF0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

2213200:BOX37 RS23625
gene id: 2213200:BOX37_RS23625
uniprot id: A0A1J0VWI3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

2213200:BOX37 RS24225
gene id: 2213200:BOX37_RS24225
uniprot id: A0A1J0VWP1
names: Similarity
messages: Belongs to the GHMP kinase family. GalK subfamily.

2213200:BOX37 RS16680
gene id: 2213200:BOX37_RS16680
uniprot id: A0A1J0VTA7
names: Similarity
messages: Belongs to the F420H(2)-dependent quinone reductase family.

2213200:BOX37 RS06865
gene id: 2213200:BOX37_RS06865
uniprot id: A0A1J0VNX7
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

2213200:BOX37 RS31345
gene id: 2213200:BOX37_RS31345
uniprot id: A0A1J0W050
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

2213200:BOX37 RS15450
gene id: 2213200:BOX37_RS15450
uniprot id: A0A1J0VSR2
names: Function
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Involved in the hydrocarbon hydroxylating system, which transfers electrons from NADH to rubredoxin reductase and then through rubredoxin to alkane 1 monooxygenase.

2213200:BOX37 RS05335
gene id: 2213200:BOX37_RS05335
uniprot id: A0A1J0VN70
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2213200:BOX37 RS26555
gene id: 2213200:BOX37_RS26555
uniprot id: A0A1J0W3C6
names: Subcellular Location Annotation
messages: Membrane

2213200:BOX37 RS24305
gene id: 2213200:BOX37_RS24305
uniprot id: A0A1J0W353
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0182 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2213200:BOX37 RS18655
gene id: 2213200:BOX37_RS18655
uniprot id: A0A1J0VU77
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

2213200:BOX37 RS05180
gene id: 2213200:BOX37_RS05180
uniprot id: A0A1J0VN81
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

2213200:BOX37 RS06565
gene id: 2213200:BOX37_RS06565
uniprot id: A0A1J0VNT5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

2213200:BOX37 RS10395
gene id: 2213200:BOX37_RS10395
uniprot id: A0A1J0VQP7
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

2213200:BOX37 RS24975
gene id: 2213200:BOX37_RS24975
uniprot id: A0A1J0VX36
names: Caution
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

2213200:BOX37 RS17255
gene id: 2213200:BOX37_RS17255
uniprot id: A0A1J0VTJ1
names: Cofactor
names: Similarity
messages: Belongs to the peptidase S45 family.
messages: Binds 1 Ca(2+) ion per dimer.

2213200:BOX37 RS01900
gene id: 2213200:BOX37_RS01900
uniprot id: A0A1J0VLL1
names: Similarity
messages: Belongs to the cysteine dioxygenase family.

2213200:BOX37 RS00875
gene id: 2213200:BOX37_RS00875
uniprot id: A0A1J0W0W1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

2213200:BOX37 RS19660
gene id: 2213200:BOX37_RS19660
uniprot id: A0A1J0W2V9
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

2213200:BOX37 RS12675
gene id: 2213200:BOX37_RS12675
uniprot id: A0A1J0W1R8
names: Subcellular Location Annotation
messages: Membrane

2213200:BOX37 RS14930
gene id: 2213200:BOX37_RS14930
uniprot id: A0A1J0VSJ9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

2213200:BOX37 RS00915
gene id: 2213200:BOX37_RS00915
uniprot id: A0A1J0VL51
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.

2213200:BOX37 RS32365
gene id: 2213200:BOX37_RS32365
uniprot id: A0A1J0W0J3
names: Function
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family. MenC type 1 subfamily.
messages: Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 2-succinylbenzoate (OSB).

2213200:BOX37 RS20995
gene id: 2213200:BOX37_RS20995
uniprot id: A0A1J0VV75
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

2213200:BOX37 RS15705
gene id: 2213200:BOX37_RS15705
uniprot id: A0A1J0VSV9
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

2213200:BOX37 RS20620
gene id: 2213200:BOX37_RS20620
uniprot id: A0A1J0W2K3
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

2213200:BOX37 RS25720
gene id: 2213200:BOX37_RS25720
uniprot id: A0A1J0VXE9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ClpS family.
messages: Binds to the N-terminal domain of the chaperone ClpA.
messages: Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.

2213200:BOX37 RS04990
gene id: 2213200:BOX37_RS04990
uniprot id: A0A1J0VN39
names: Similarity
messages: Belongs to the peptidase S51 family.

2213200:BOX37 RS28945
gene id: 2213200:BOX37_RS28945
uniprot id: A0A1J0W3G4
names: Similarity
messages: Belongs to the UDPGP type 2 family.

2213200:BOX37 RS10160
gene id: 2213200:BOX37_RS10160
uniprot id: A0A1J0VQF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

2213200:BOX37 RS03045
gene id: 2213200:BOX37_RS03045
uniprot id: A0A1J0W141
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

2213200:BOX37 RS06620
gene id: 2213200:BOX37_RS06620
uniprot id: A0A1J0VNR8
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

2213200:BOX37 RS30930
gene id: 2213200:BOX37_RS30930
uniprot id: A0A1J0VZK7
names: Subcellular Location Annotation
messages: Membrane

2213200:BOX37 RS12290
gene id: 2213200:BOX37_RS12290
uniprot id: A0A1J0VRA8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

2213200:BOX37 RS26115
gene id: 2213200:BOX37_RS26115
uniprot id: A0A1J0VXN5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

2213200:BOX37 RS17955
gene id: 2213200:BOX37_RS17955
uniprot id: A0A1J0VTX2
names: Similarity
messages: Belongs to the asp23 family.

2213200:BOX37 RS32535
gene id: 2213200:BOX37_RS32535
uniprot id: A0A1J0W0P9
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2213200:BOX37 RS33085
gene id: 2213200:BOX37_RS33085
uniprot id: A0A1J0W0S5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

2213200:BOX37 RS07180
gene id: 2213200:BOX37_RS07180
uniprot id: A0A1J0VP31
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

2213200:BOX37 RS01390
gene id: 2213200:BOX37_RS01390
uniprot id: A0A1J0VLD2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homotetramer.

2213200:BOX37 RS21300
gene id: 2213200:BOX37_RS21300
uniprot id: A0A1J0VVH3
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family. MbtB subfamily.

2213200:BOX37 RS08565
gene id: 2213200:BOX37_RS08565
uniprot id: A0A1J0VPU6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

2213200:BOX37 RS24400
gene id: 2213200:BOX37_RS24400
uniprot id: A0A1J0VX30
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acireductone dioxygenase (ARD) family.
messages: Binds 1 Fe(2+) cation per monomer.
messages: Binds 1 nickel ion per monomer.
messages: Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
messages: Monomer.

2213200:BOX37 RS03920
gene id: 2213200:BOX37_RS03920
uniprot id: A0A1J0VMK7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

2213200:BOX37 RS31550
gene id: 2213200:BOX37_RS31550
uniprot id: A0A1J0W0B8
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

2213200:BOX37 RS31250
gene id: 2213200:BOX37_RS31250
uniprot id: A0A1J0W3K6
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

2213200:BOX37 RS14675
gene id: 2213200:BOX37_RS14675
uniprot id: A0A1J0VSN4
names: Similarity
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.

2213200:BOX37 RS02405
gene id: 2213200:BOX37_RS02405
uniprot id: A0A1J0VLW2
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

2213200:BOX37 RS19580
gene id: 2213200:BOX37_RS19580
uniprot id: A0A1J0VUK5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

2213200:BOX37 RS21025
gene id: 2213200:BOX37_RS21025
uniprot id: A0A1J0VVD6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

2213200:BOX37 RS19010
gene id: 2213200:BOX37_RS19010
uniprot id: A0A1J0VUC2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

2213200:BOX37 RS25675
gene id: 2213200:BOX37_RS25675
uniprot id: A0A1J0VXD6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

2213200:BOX37 RS21565
gene id: 2213200:BOX37_RS21565
uniprot id: A0A1J0VVL3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

2213200:BOX37 RS08130
gene id: 2213200:BOX37_RS08130
uniprot id: A0A1J0VPH7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Homotetramer.

2213200:BOX37 RS20065
gene id: 2213200:BOX37_RS20065
uniprot id: A0A1J0VUT4
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2213200:BOX37 RS03760
gene id: 2213200:BOX37_RS03760
uniprot id: A0A1J0VMG0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

2213200:BOX37 RS04640
gene id: 2213200:BOX37_RS04640
uniprot id: A0A1J0VMX0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2213200:BOX37 RS10675
gene id: 2213200:BOX37_RS10675
uniprot id: A0A1J0W1Z4
names: Cofactor
names: Similarity
messages: Belongs to the fatty acid desaturase type 2 family.
messages: Binds 2 iron ions per subunit.

2213200:BOX37 RS06585
gene id: 2213200:BOX37_RS06585
uniprot id: A0A1J0VNS9
names: Similarity
messages: Belongs to the SAICAR synthetase family.

2213200:BOX37 RS14040
gene id: 2213200:BOX37_RS14040
uniprot id: A0A1J0VS29
names: Similarity
messages: Belongs to the CsoR family.

2213200:BOX37 RS19875
gene id: 2213200:BOX37_RS19875
uniprot id: A0A1J0VV18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

2213200:BOX37 RS22305
gene id: 2213200:BOX37_RS22305
uniprot id: A0A1J0VVW2
names: Similarity
messages: Belongs to the cytochrome P450 family.

2213200:BOX37 RS03090
gene id: 2213200:BOX37_RS03090
uniprot id: A0A1J0VM68
names: Similarity
messages: Belongs to the transglycosylase family. Rpf subfamily.

2213200:BOX37 RS14450
gene id: 2213200:BOX37_RS14450
uniprot id: A0A1J0VS97
names: Similarity
messages: Belongs to the cytochrome P450 family.

2213200:BOX37 RS13265
gene id: 2213200:BOX37_RS13265
uniprot id: A0A1J0VRQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 2 subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

2213200:BOX37 RS03450
gene id: 2213200:BOX37_RS03450
uniprot id: A0A1J0VMC1
names: Similarity
messages: Belongs to the HipA Ser/Thr kinase family.

2213200:BOX37 RS21520
gene id: 2213200:BOX37_RS21520
uniprot id: A0A1J0VVF5
names: Similarity
messages: Belongs to the MQO family.

2213200:BOX37 RS09445
gene id: 2213200:BOX37_RS09445
uniprot id: A0A1J0VQ14
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2213200:BOX37 RS21705
gene id: 2213200:BOX37_RS21705
uniprot id: A0A1J0W2T3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Membrane

2213200:BOX37 RS29680
gene id: 2213200:BOX37_RS29680
uniprot id: A0A1J0VZ40
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

2213200:BOX37 RS24745
gene id: 2213200:BOX37_RS24745
uniprot id: A0A1J0VX02
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

2213200:BOX37 RS11940
gene id: 2213200:BOX37_RS11940
uniprot id: A0A1J0VR85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

2213200:BOX37 RS29960
gene id: 2213200:BOX37_RS29960
uniprot id: A0A1J0VZE3
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

2213200:BOX37 RS29555
gene id: 2213200:BOX37_RS29555
uniprot id: A0A1J0W3F6
names: Subcellular Location Annotation
messages: Membrane

2213200:BOX37 RS17360
gene id: 2213200:BOX37_RS17360
uniprot id: A0A1J0VTK5
names: Similarity
messages: Belongs to the TPP enzyme family.

2213200:BOX37 RS18525
gene id: 2213200:BOX37_RS18525
uniprot id: A0A1J0VU51
names: Subcellular Location Annotation
messages: Membrane

2213200:BOX37 RS30090
gene id: 2213200:BOX37_RS30090
uniprot id: A0A1J0VZ58
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

2213200:BOX37 RS19980
gene id: 2213200:BOX37_RS19980
uniprot id: A0A1J0VUT0
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

2213200:BOX37 RS26120
gene id: 2213200:BOX37_RS26120
uniprot id: A0A1J0VXG8
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

2213200:BOX37 RS12265
gene id: 2213200:BOX37_RS12265
uniprot id: A0A1J0VRC0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

2213200:BOX37 RS07710
gene id: 2213200:BOX37_RS07710
uniprot id: A0A1J0VP98
names: Similarity
messages: Belongs to the AHA1 family.

2213200:BOX37 RS04130
gene id: 2213200:BOX37_RS04130
uniprot id: A0A1J0VMP2
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

2213200:BOX37 RS02620
gene id: 2213200:BOX37_RS02620
uniprot id: A0A1J0VLY1
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

2213200:BOX37 RS19900
gene id: 2213200:BOX37_RS19900
uniprot id: A0A1J0VUR1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

2213200:BOX37 RS21985
gene id: 2213200:BOX37_RS21985
uniprot id: A0A1J0VVM4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

2213200:BOX37 RS02245
gene id: 2213200:BOX37_RS02245
uniprot id: A0A1J0VLS3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

2213200:BOX37 RS32040
gene id: 2213200:BOX37_RS32040
uniprot id: A0A1J0W0B6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.
messages: Cytoplasm
messages: Monomer.

2213200:BOX37 RS03065
gene id: 2213200:BOX37_RS03065
uniprot id: A0A1J0VM45
names: Similarity
messages: Belongs to the peptidase M1 family.

2213200:BOX37 RS01860
gene id: 2213200:BOX37_RS01860
uniprot id: A0A1J0VLK4
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

2213200:BOX37 RS30725
gene id: 2213200:BOX37_RS30725
uniprot id: A0A1J0VZR0
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

2213200:BOX37 RS22535
gene id: 2213200:BOX37_RS22535
uniprot id: A0A1J0VVV9
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

2213200:BOX37 RS10760
gene id: 2213200:BOX37_RS10760
uniprot id: A0A1J0VQK7
names: Similarity
messages: Belongs to the HupF/HypC family.

2213200:BOX37 RS00980
gene id: 2213200:BOX37_RS00980
uniprot id: A0A1J0W0P8
names: Subcellular Location Annotation
messages: Membrane

2213200:BOX37 RS14535
gene id: 2213200:BOX37_RS14535
uniprot id: A0A1J0VSL0
names: Subcellular Location Annotation
messages: Membrane

2213200:BOX37 RS27415
gene id: 2213200:BOX37_RS27415
uniprot id: A0A1J0VY38
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

2213200:BOX37 RS05515
gene id: 2213200:BOX37_RS05515
uniprot id: A0A1J0VN92
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

2213200:BOX37 RS06770
gene id: 2213200:BOX37_RS06770
uniprot id: A0A1J0W1L9
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

2213200:BOX37 RS10245
gene id: 2213200:BOX37_RS10245
uniprot id: A0A1J0VQD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family. Mmr subfamily.
messages: Cell membrane
messages: Membrane

2213200:BOX37 RS17245
gene id: 2213200:BOX37_RS17245
uniprot id: A0A1J0VTK8
names: Similarity
messages: Belongs to the group II decarboxylase family.

2213200:BOX37 RS09780
gene id: 2213200:BOX37_RS09780
uniprot id: A0A1J0VQ93
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.

2213200:BOX37 RS19530
gene id: 2213200:BOX37_RS19530
uniprot id: A0A1J0VUL1
names: Similarity
names: Subunit
messages: Belongs to the sigma-70 factor family. ECF subfamily.
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

2213200:BOX37 RS09725
gene id: 2213200:BOX37_RS09725
uniprot id: A0A1J0VQ86
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

2213200:BOX37 RS09610
gene id: 2213200:BOX37_RS09610
uniprot id: A0A1J0VQ36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

2213200:BOX37 RS18605
gene id: 2213200:BOX37_RS18605
uniprot id: A0A1J0VU56
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: Could possibly oxidize fatty acids using specific components.

2213200:BOX37 RS30855
gene id: 2213200:BOX37_RS30855
uniprot id: A0A1J0VZM7
names: Subcellular Location Annotation
messages: Membrane

2213200:BOX37 RS30660
gene id: 2213200:BOX37_RS30660
uniprot id: A0A1J0VZM9
names: Subcellular Location Annotation
messages: Membrane

2213200:BOX37 RS21765
gene id: 2213200:BOX37_RS21765
uniprot id: A0A1J0VVH7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2213200:BOX37 RS19985
gene id: 2213200:BOX37_RS19985
uniprot id: A0A1J0VUV9
names: Similarity
messages: Belongs to the AHA1 family.

2213200:BOX37 RS03715
gene id: 2213200:BOX37_RS03715
uniprot id: A0A1J0VMF5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

2213200:BOX37 RS04000
gene id: 2213200:BOX37_RS04000
uniprot id: A0A1J0VMJ3
names: Similarity
messages: Belongs to the EspG family.

2213200:BOX37 RS10250
gene id: 2213200:BOX37_RS10250
uniprot id: A0A1J0VQF6
names: Similarity
messages: Belongs to the serine/threonine dehydratase family.

2213200:BOX37 RS26440
gene id: 2213200:BOX37_RS26440
uniprot id: A0A1J0VXU7
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

2213200:BOX37 RS15735
gene id: 2213200:BOX37_RS15735
uniprot id: A0A1J0VSX1
names: Similarity
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.

2213200:BOX37 RS14560
gene id: 2213200:BOX37_RS14560
uniprot id: A0A1J0VSB2
names: Subcellular Location Annotation
messages: Membrane

2213200:BOX37 RS07475
gene id: 2213200:BOX37_RS07475
uniprot id: A0A1J0W1G2
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

2213200:BOX37 RS11010
gene id: 2213200:BOX37_RS11010
uniprot id: A0A1J0VQR8
names: Similarity
messages: Belongs to the cytochrome P450 family.

2213200:BOX37 RS13215
gene id: 2213200:BOX37_RS13215
uniprot id: A0A1J0W1V5
names: Similarity
messages: Belongs to the non-flavoprotein flavin reductase family.

2213200:BOX37 RS22110
gene id: 2213200:BOX37_RS22110
uniprot id: A0A1J0VVV2
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

2213200:BOX37 RS07140
gene id: 2213200:BOX37_RS07140
uniprot id: A0A1J0W180
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

2213200:BOX37 RS04510
gene id: 2213200:BOX37_RS04510
uniprot id: A0A1J0VMU4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-C family. DnaE2 subfamily.
messages: Cytoplasm
messages: DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase.

2213200:BOX37 RS00240
gene id: 2213200:BOX37_RS00240
uniprot id: A0A1J0VKX9
names: Subcellular Location Annotation
messages: Membrane

2213200:BOX37 RS19435
gene id: 2213200:BOX37_RS19435
uniprot id: A0A1J0VUJ7
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2213200:BOX37 RS05325
gene id: 2213200:BOX37_RS05325
uniprot id: A0A1J0VN83
names: Function
names: Similarity
messages: Belongs to the threonine synthase family.
messages: Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.

2213200:BOX37 RS00525
gene id: 2213200:BOX37_RS00525
uniprot id: A0A1J0VL20
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.

2213200:BOX37 RS16485
gene id: 2213200:BOX37_RS16485
uniprot id: A0A1J0VT63
names: Similarity
messages: Belongs to the peptidase S33 family.

2213200:BOX37 RS00400
gene id: 2213200:BOX37_RS00400
uniprot id: A0A1J0VL00
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

2213200:BOX37 RS26430
gene id: 2213200:BOX37_RS26430
uniprot id: A0A1J0VXK7
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

2213200:BOX37 RS25090
gene id: 2213200:BOX37_RS25090
uniprot id: A0A1J0W329
names: Similarity
messages: Belongs to the cytochrome P450 family.

2213200:BOX37 RS05955
gene id: 2213200:BOX37_RS05955
uniprot id: A0A1J0VNI6
names: Subcellular Location Annotation
messages: Membrane

2213200:BOX37 RS04580
gene id: 2213200:BOX37_RS04580
uniprot id: A0A1J0VMT8
names: Activity Regulation
names: Caution
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2213200:BOX37 RS26145
gene id: 2213200:BOX37_RS26145
uniprot id: A0A1J0W358
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

2213200:BOX37 RS01285
gene id: 2213200:BOX37_RS01285
uniprot id: A0A1J0VLE3
names: Similarity
messages: Belongs to the protein kinase superfamily.

2213200:BOX37 RS27805
gene id: 2213200:BOX37_RS27805
uniprot id: A0A1J0VYE7
names: Subcellular Location Annotation
messages: Membrane

2213200:BOX37 RS09765
gene id: 2213200:BOX37_RS09765
uniprot id: A0A1J0VQE3
names: Subcellular Location Annotation
messages: Membrane

2213200:BOX37 RS15555
gene id: 2213200:BOX37_RS15555
uniprot id: A0A1J0VSS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

2213200:BOX37 RS21865
gene id: 2213200:BOX37_RS21865
uniprot id: A0A1J0VVW5
names: Similarity
messages: Belongs to the UPF0102 family.

2213200:BOX37 RS06570
gene id: 2213200:BOX37_RS06570
uniprot id: A0A1J0VNQ5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2213200:BOX37 RS03220
gene id: 2213200:BOX37_RS03220
uniprot id: A0A1J0VM73
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

2213200:BOX37 RS21305
gene id: 2213200:BOX37_RS21305
uniprot id: A0A1J0VVC0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

2213200:BOX37 RS09595
gene id: 2213200:BOX37_RS09595
uniprot id: A0A1J0VQ65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

2213200:BOX37 RS25100
gene id: 2213200:BOX37_RS25100
uniprot id: A0A1J0W3F2
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

2213200:BOX37 RS12075
gene id: 2213200:BOX37_RS12075
uniprot id: A0A1J0VR95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

2213200:BOX37 RS09585
gene id: 2213200:BOX37_RS09585
uniprot id: A0A1J0VQB3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

2213200:BOX37 RS23360
gene id: 2213200:BOX37_RS23360
uniprot id: A0A1J0VWE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Membrane

2213200:BOX37 RS34655
gene id: 2213200:BOX37_RS34655
uniprot id: A0A1J0VSM1
names: Subcellular Location Annotation
messages: Membrane

2213200:BOX37 RS14195
gene id: 2213200:BOX37_RS14195
uniprot id: A0A1J0VS67
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

2213200:BOX37 RS07370
gene id: 2213200:BOX37_RS07370
uniprot id: A0A1J0VP43
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

2213200:BOX37 RS02050
gene id: 2213200:BOX37_RS02050
uniprot id: A0A1J0VLP1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

2213200:BOX37 RS06940
gene id: 2213200:BOX37_RS06940
uniprot id: A0A1J0VNY5
names: Subcellular Location Annotation
messages: Membrane

2213200:BOX37 RS05725
gene id: 2213200:BOX37_RS05725
uniprot id: A0A1J0VNE8
names: Similarity
messages: Belongs to the HIBADH-related family.

2213200:BOX37 RS04780
gene id: 2213200:BOX37_RS04780
uniprot id: A0A1J0VMZ8
names: Similarity
messages: Belongs to the peptidase M20A family.

2213200:BOX37 RS17390
gene id: 2213200:BOX37_RS17390
uniprot id: A0A1J0VTN1
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

2213200:BOX37 RS00500
gene id: 2213200:BOX37_RS00500
uniprot id: A0A1J0VL11
names: Similarity
messages: Belongs to the mycobacterial PPE family.

2213200:BOX37 RS23875
gene id: 2213200:BOX37_RS23875
uniprot id: A0A1J0VWU5
names: Similarity
messages: Belongs to the Nudix hydrolase family.

2213200:BOX37 RS10060
gene id: 2213200:BOX37_RS10060
uniprot id: A0A1J0VQA1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PEPCase type 1 family.
messages: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
messages: Homotetramer.

2213200:BOX37 RS26285
gene id: 2213200:BOX37_RS26285
uniprot id: A0A1J0VXY4
names: Similarity
messages: Belongs to the adenylyl cyclase class-3 family.

2213200:BOX37 RS03755
gene id: 2213200:BOX37_RS03755
uniprot id: A0A1J0VMG1
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

2213200:BOX37 RS30840
gene id: 2213200:BOX37_RS30840
uniprot id: A0A1J0VZI6
names: Similarity
messages: Belongs to the AAA ATPase family.

2213200:BOX37 RS25875
gene id: 2213200:BOX37_RS25875
uniprot id: A0A1J0W341
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type 2 tetrahydrodipicolinate N-succinyltransferase family.
messages: Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2-amino-6-oxopimelate using succinyl-CoA.
messages: Cytoplasm
messages: Homotrimer.

2213200:BOX37 RS06645
gene id: 2213200:BOX37_RS06645
uniprot id: A0A1J0VNS2
names: Similarity
messages: Belongs to the LacAB/RpiB family.

2213200:BOX37 RS07805
gene id: 2213200:BOX37_RS07805
uniprot id: A0A1J0VPB3
names: Similarity
messages: Belongs to the MT-A70-like family.

2213200:BOX37 RS10715
gene id: 2213200:BOX37_RS10715
uniprot id: A0A1J0VQP5
names: Function
names: Similarity
messages: Belongs to the HypA/HybF family.
messages: Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.

2213200:BOX37 RS19380
gene id: 2213200:BOX37_RS19380
uniprot id: A0A1J0W2J0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

2213200:BOX37 RS23580
gene id: 2213200:BOX37_RS23580
uniprot id: A0A1J0W2W4
names: Similarity
messages: Belongs to the DODA-type extradiol aromatic ring-opening dioxygenase family.

2213200:BOX37 RS15770
gene id: 2213200:BOX37_RS15770
uniprot id: A0A1J0VT66
names: Similarity
messages: Belongs to the CmpA/NrtA family.

2213200:BOX37 RS11720
gene id: 2213200:BOX37_RS11720
uniprot id: A0A1J0VR49
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

2213200:BOX37 RS09440
gene id: 2213200:BOX37_RS09440
uniprot id: A0A1J0W1N2
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

2213200:BOX37 RS18795
gene id: 2213200:BOX37_RS18795
uniprot id: A0A1J0VUB4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

2213200:BOX37 RS22555
gene id: 2213200:BOX37_RS22555
uniprot id: A0A1J0VVY8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhD family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.

2213200:BOX37 RS25000
gene id: 2213200:BOX37_RS25000
uniprot id: A0A1J0VX29
names: Function
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Involved in the hydrocarbon hydroxylating system, which transfers electrons from NADH to rubredoxin reductase and then through rubredoxin to alkane 1 monooxygenase.

2213200:BOX37 RS09390
gene id: 2213200:BOX37_RS09390
uniprot id: A0A1J0W1N1
names: Similarity
messages: Belongs to the F420H(2)-dependent quinone reductase family.

2213200:BOX37 RS06740
gene id: 2213200:BOX37_RS06740
uniprot id: A0A1J0VNV4
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

2213200:BOX37 RS25175
gene id: 2213200:BOX37_RS25175
uniprot id: A0A1J0W325
names: Subcellular Location Annotation
messages: Membrane

2213200:BOX37 RS17195
gene id: 2213200:BOX37_RS17195
uniprot id: A0A1J0VTI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Membrane

2213200:BOX37 RS24735
gene id: 2213200:BOX37_RS24735
uniprot id: A0A1J0VWV2
names: Subcellular Location Annotation
messages: Membrane

2213200:BOX37 RS24110
gene id: 2213200:BOX37_RS24110
uniprot id: A0A1J0W322
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

2213200:BOX37 RS10565
gene id: 2213200:BOX37_RS10565
uniprot id: A0A1J0VQK5
names: Similarity
messages: Belongs to the AHA1 family.

2213200:BOX37 RS21815
gene id: 2213200:BOX37_RS21815
uniprot id: A0A1J0VVV7
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

2213200:BOX37 RS28180
gene id: 2213200:BOX37_RS28180
uniprot id: A0A1J0VYE8
names: Similarity
messages: Belongs to the cytochrome P450 family.

2213200:BOX37 RS01515
gene id: 2213200:BOX37_RS01515
uniprot id: A0A1J0VLH7
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

2213200:BOX37 RS10615
gene id: 2213200:BOX37_RS10615
uniprot id: A0A1J0VQJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2213200:BOX37 RS15880
gene id: 2213200:BOX37_RS15880
uniprot id: A0A1J0VSX6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

2213200:BOX37 RS09895
gene id: 2213200:BOX37_RS09895
uniprot id: A0A1J0VQ89
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

2213200:BOX37 RS11065
gene id: 2213200:BOX37_RS11065
uniprot id: A0A1J0VQQ9
names: Subcellular Location Annotation
messages: Membrane

2213200:BOX37 RS29260
gene id: 2213200:BOX37_RS29260
uniprot id: A0A1J0VZ30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the encapsulin family. Family 1 subfamily.
messages: Encapsulin nanocompartment

2213200:BOX37 RS17230
gene id: 2213200:BOX37_RS17230
uniprot id: A0A1J0VTI7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

2213200:BOX37 RS30965
gene id: 2213200:BOX37_RS30965
uniprot id: A0A1J0W027
names: Similarity
messages: Belongs to the AHA1 family.

2213200:BOX37 RS06895
gene id: 2213200:BOX37_RS06895
uniprot id: A0A1J0VNX8
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

2213200:BOX37 RS19475
gene id: 2213200:BOX37_RS19475
uniprot id: A0A1J0VUK2
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2213200:BOX37 RS23080
gene id: 2213200:BOX37_RS23080
uniprot id: A0A1J0VW36
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpA family.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds the extracellular potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

2213200:BOX37 RS24115
gene id: 2213200:BOX37_RS24115
uniprot id: A0A1J0VWR2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division.

2213200:BOX37 RS10790
gene id: 2213200:BOX37_RS10790
uniprot id: A0A1J0VQP4
names: Similarity
messages: Belongs to the HupF/HypC family.

2213200:BOX37 RS19655
gene id: 2213200:BOX37_RS19655
uniprot id: A0A1J0VUL5
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

2213200:BOX37 RS29295
gene id: 2213200:BOX37_RS29295
uniprot id: A0A1J0VYX4
names: Similarity
messages: Belongs to the peptidase S33 family.

2213200:BOX37 RS22165
gene id: 2213200:BOX37_RS22165
uniprot id: A0A1J0VVN7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

2213200:BOX37 RS08575
gene id: 2213200:BOX37_RS08575
uniprot id: A0A1J0VPN1
names: Subcellular Location Annotation
messages: Membrane

2213200:BOX37 RS11510
gene id: 2213200:BOX37_RS11510
uniprot id: A0A1J0VR75
names: Similarity
messages: Belongs to the iron/ascorbate-dependent oxidoreductase family.

2213200:BOX37 RS11540
gene id: 2213200:BOX37_RS11540
uniprot id: A0A1J0VQZ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM61 family.
messages: Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA.
messages: Homotetramer composed of a dimer of dimers.

2213200:BOX37 RS13025
gene id: 2213200:BOX37_RS13025
uniprot id: A0A1J0VRM6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

2213200:BOX37 RS18450
gene id: 2213200:BOX37_RS18450
uniprot id: A0A1J0VU31
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

2213200:BOX37 RS04350
gene id: 2213200:BOX37_RS04350
uniprot id: A0A1J0VMT5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2213200:BOX37 RS09985
gene id: 2213200:BOX37_RS09985
uniprot id: A0A1J0VQA6
names: Subcellular Location Annotation
messages: Membrane

2213200:BOX37 RS15850
gene id: 2213200:BOX37_RS15850
uniprot id: A0A1J0VSY1
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

2213200:BOX37 RS16750
gene id: 2213200:BOX37_RS16750
uniprot id: A0A1J0VTE6
names: Similarity
messages: Belongs to the PAPS reductase family. CysD subfamily.

2213200:BOX37 RS19295
gene id: 2213200:BOX37_RS19295
uniprot id: A0A1J0VUT9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

2213200:BOX37 RS29590
gene id: 2213200:BOX37_RS29590
uniprot id: A0A1J0VZ23
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

2213200:BOX37 RS24680
gene id: 2213200:BOX37_RS24680
uniprot id: A0A1J0VWZ9
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

2213200:BOX37 RS12350
gene id: 2213200:BOX37_RS12350
uniprot id: A0A1J0VRC1
names: Similarity
messages: Belongs to the phosphoribulokinase family.

2213200:BOX37 RS09710
gene id: 2213200:BOX37_RS09710
uniprot id: A0A1J0VQ78
names: Subcellular Location Annotation
messages: Membrane

2213200:BOX37 RS24790
gene id: 2213200:BOX37_RS24790
uniprot id: A0A1J0VX14
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

2213200:BOX37 RS18600
gene id: 2213200:BOX37_RS18600
uniprot id: A0A1J0VUA4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

2213200:BOX37 RS19110
gene id: 2213200:BOX37_RS19110
uniprot id: A0A1J0VUF7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic Ku family.
messages: Homodimer. Interacts with LigD.
messages: With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD.

2213200:BOX37 RS14520
gene id: 2213200:BOX37_RS14520
uniprot id: A0A1J0VSA2
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

2213200:BOX37 RS14630
gene id: 2213200:BOX37_RS14630
uniprot id: A0A1J0VSD0
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

2213200:BOX37 RS21625
gene id: 2213200:BOX37_RS21625
uniprot id: A0A1J0VVG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Cell membrane
messages: Membrane

2213200:BOX37 RS09970
gene id: 2213200:BOX37_RS09970
uniprot id: A0A1J0VQA4
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

2213200:BOX37 RS07720
gene id: 2213200:BOX37_RS07720
uniprot id: A0A1J0VPB4
names: Function
messages: TetR is the repressor of the tetracycline resistance element; its N-terminal region forms a helix-turn-helix structure and binds DNA. Binding of tetracycline to TetR reduces the repressor affinity for the tetracycline resistance gene (tetA) promoter operator sites.

2213200:BOX37 RS13645
gene id: 2213200:BOX37_RS13645
uniprot id: A0A1J0VRY2
names: Function
names: Similarity
messages: Belongs to the MqnA/MqnD family. MqnA subfamily.
messages: Catalyzes the dehydration of chorismate into 3-[(1-carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2).

2213200:BOX37 RS11170
gene id: 2213200:BOX37_RS11170
uniprot id: A0A1J0VQU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2213200:BOX37 RS01720
gene id: 2213200:BOX37_RS01720
uniprot id: A0A1J0W102
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

2213200:BOX37 RS02820
gene id: 2213200:BOX37_RS02820
uniprot id: A0A1J0VM40
names: Caution
names: Similarity
messages: Belongs to the nitrobindin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Lacks the conserved His residue that binds heme iron in the nitrobindin family.

2213200:BOX37 RS32980
gene id: 2213200:BOX37_RS32980
uniprot id: A0A1J0W0Q8
names: Similarity
messages: Belongs to the pirin family.

2213200:BOX37 RS12775
gene id: 2213200:BOX37_RS12775
uniprot id: A0A1J0VRK5
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

2213200:BOX37 RS21800
gene id: 2213200:BOX37_RS21800
uniprot id: A0A1J0W2Z1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

2213200:BOX37 RS01615
gene id: 2213200:BOX37_RS01615
uniprot id: A0A1J0VLI5
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

2213200:BOX37 RS26320
gene id: 2213200:BOX37_RS26320
uniprot id: A0A1J0VXQ4
names: Subcellular Location Annotation
messages: Membrane

2213200:BOX37 RS25195
gene id: 2213200:BOX37_RS25195
uniprot id: A0A1J0VX06
names: Similarity
messages: Belongs to the AP endonuclease 2 family.

2213200:BOX37 RS19310
gene id: 2213200:BOX37_RS19310
uniprot id: A0A1J0VUL9
names: Function
names: Similarity
messages: Belongs to the WhiA family.
messages: Involved in cell division and chromosome segregation.

2213200:BOX37 RS23480
gene id: 2213200:BOX37_RS23480
uniprot id: A0A1J0VWC8
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Electron transport system for the ribonucleotide reductase system NrdEF.

2213200:BOX37 RS07045
gene id: 2213200:BOX37_RS07045
uniprot id: A0A1J0VP03
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

2213200:BOX37 RS21920
gene id: 2213200:BOX37_RS21920
uniprot id: A0A1J0VVK2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

2213200:BOX37 RS31600
gene id: 2213200:BOX37_RS31600
uniprot id: A0A1J0W0C5
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: Could possibly oxidize fatty acids using specific components.

2213200:BOX37 RS21955
gene id: 2213200:BOX37_RS21955
uniprot id: A0A1J0VVX8
names: Subcellular Location Annotation
messages: Membrane

2213200:BOX37 RS10705
gene id: 2213200:BOX37_RS10705
uniprot id: A0A1J0VQJ9
names: Subcellular Location Annotation
messages: Membrane

2213200:BOX37 RS11400
gene id: 2213200:BOX37_RS11400
uniprot id: A0A1J0VQZ9
names: Similarity
messages: Belongs to the creatininase superfamily.

2213200:BOX37 RS26195
gene id: 2213200:BOX37_RS26195
uniprot id: A0A1J0VXW8
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

2213200:BOX37 RS03940
gene id: 2213200:BOX37_RS03940
uniprot id: A0A1J0VMM1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

2213200:BOX37 RS07195
gene id: 2213200:BOX37_RS07195
uniprot id: A0A1J0VP12
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

2213200:BOX37 RS04685
gene id: 2213200:BOX37_RS04685
uniprot id: A0A1J0W118
names: Similarity
messages: Belongs to the cytochrome P450 family.

2213200:BOX37 RS17980
gene id: 2213200:BOX37_RS17980
uniprot id: A0A1J0VTV5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

2213200:BOX37 RS27850
gene id: 2213200:BOX37_RS27850
uniprot id: A0A1J0VYF4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

2213200:BOX37 RS29640
gene id: 2213200:BOX37_RS29640
uniprot id: A0A1J0VZ99
names: Similarity
messages: Belongs to the iron/ascorbate-dependent oxidoreductase family.

2213200:BOX37 RS19930
gene id: 2213200:BOX37_RS19930
uniprot id: A0A1J0VUU9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

2213200:BOX37 RS15130
gene id: 2213200:BOX37_RS15130
uniprot id: A0A1J0W2D2
names: Subcellular Location Annotation
messages: Membrane

2213200:BOX37 RS26325
gene id: 2213200:BOX37_RS26325
uniprot id: A0A1J0VXQ0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial microcompartment
messages: Belongs to the EutB family.
messages: Binds between the large and small subunits.
messages: Catalyzes the deamination of various vicinal amino-alcohols to oxo compounds. Allows this organism to utilize ethanolamine as the sole source of nitrogen and carbon in the presence of vitamin B12.
messages: The basic unit is a heterodimer which dimerizes to form tetramers. The heterotetramers trimerize; 6 large subunits form a core ring with 6 small subunits projecting outwards.

2213200:BOX37 RS05340
gene id: 2213200:BOX37_RS05340
uniprot id: A0A1J0VN85
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

2213200:BOX37 RS18740
gene id: 2213200:BOX37_RS18740
uniprot id: A0A1J0VU86
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

2213200:BOX37 RS00650
gene id: 2213200:BOX37_RS00650
uniprot id: A0A1J0VL35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

2213200:BOX37 RS21725
gene id: 2213200:BOX37_RS21725
uniprot id: A0A1J0VVN8
names: Cofactor
names: Domain
names: Function
names: Similarity
messages: Belongs to the nitrobindin family.
messages: Binds 1 heme b group per subunit, that coordinates a highly solvent-exposed Fe(III) atom.
messages: Forms a 10-stranded antiparallel beta-barrel structure able to accommodate a hydrophobic ligand in its interior. In fact, this fold hosts the heme group, which is located in a wide surface cleft.
messages: Heme-binding protein able to scavenge peroxynitrite and to protect free L-tyrosine against peroxynitrite-mediated nitration, by acting as a peroxynitrite isomerase that converts peroxynitrite to nitrate. Therefore, this protein likely plays a role in peroxynitrite sensing and in the detoxification of reactive nitrogen and oxygen species (RNS and ROS, respectively). Is able to bind nitric oxide (NO) in vitro, but may act as a sensor of peroxynitrite levels in vivo.

2213200:BOX37 RS11260
gene id: 2213200:BOX37_RS11260
uniprot id: A0A1J0VQU1
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild-type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity.
messages: Belongs to the RecC family.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding.

2213200:BOX37 RS00975
gene id: 2213200:BOX37_RS00975
uniprot id: A0A1J0VL62
names: Similarity
messages: Belongs to the ABC transporter superfamily.

2213200:BOX37 RS15415
gene id: 2213200:BOX37_RS15415
uniprot id: A0A1J0VSQ1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

2213200:BOX37 RS15970
gene id: 2213200:BOX37_RS15970
uniprot id: A0A1J0W227
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

2213200:BOX37 RS06825
gene id: 2213200:BOX37_RS06825
uniprot id: A0A1J0VNX5
names: Similarity
messages: Belongs to the EspG family.

2213200:BOX37 RS14935
gene id: 2213200:BOX37_RS14935
uniprot id: A0A1J0VSH5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2213200:BOX37 RS03925
gene id: 2213200:BOX37_RS03925
uniprot id: A0A1J0VMI9
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

2213200:BOX37 RS13365
gene id: 2213200:BOX37_RS13365
uniprot id: A0A1J0VRR6
names: Cofactor
names: PTM
names: Similarity
messages: Belongs to the copper/topaquinone oxidase family.
messages: Contains 1 topaquinone per subunit.
messages: Topaquinone (TPQ) is generated by copper-dependent autoxidation of a specific tyrosyl residue.

2213200:BOX37 RS24240
gene id: 2213200:BOX37_RS24240
uniprot id: A0A1J0VX03
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

2213200:BOX37 RS30250
gene id: 2213200:BOX37_RS30250
uniprot id: A0A1J0VZG9
names: Function
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

2213200:BOX37 RS19690
gene id: 2213200:BOX37_RS19690
uniprot id: A0A1J0VUN3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.

2213200:BOX37 RS32435
gene id: 2213200:BOX37_RS32435
uniprot id: A0A1J0W0J8
names: Similarity
messages: Belongs to the myo-inositol 1-phosphate synthase family.

2213200:BOX37 RS14315
gene id: 2213200:BOX37_RS14315
uniprot id: A0A1J0W230
names: Similarity
messages: Belongs to the cytochrome P450 family.

2213200:BOX37 RS09015
gene id: 2213200:BOX37_RS09015
uniprot id: A0A1J0VPY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

2213200:BOX37 RS31395
gene id: 2213200:BOX37_RS31395
uniprot id: A0A1J0W057
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

2213200:BOX37 RS03935
gene id: 2213200:BOX37_RS03935
uniprot id: A0A1J0VMI5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

2213200:BOX37 RS07440
gene id: 2213200:BOX37_RS07440
uniprot id: A0A1J0VP70
names: Similarity
messages: Belongs to the long-chain O-acyltransferase family.

2213200:BOX37 RS07160
gene id: 2213200:BOX37_RS07160
uniprot id: A0A1J0VP33
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

2213200:BOX37 RS02525
gene id: 2213200:BOX37_RS02525
uniprot id: A0A1J0VLW3
names: Similarity
messages: Belongs to the glycosyltransferase 20 family.

2213200:BOX37 RS04700
gene id: 2213200:BOX37_RS04700
uniprot id: A0A1J0VMW9
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

2213200:BOX37 RS19320
gene id: 2213200:BOX37_RS19320
uniprot id: A0A1J0VUI4
names: Function
names: Similarity
messages: Belongs to the RapZ-like family.
messages: Displays ATPase and GTPase activities.

2213200:BOX37 RS24385
gene id: 2213200:BOX37_RS24385
uniprot id: A0A1J0VWR8
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

2213200:BOX37 RS03745
gene id: 2213200:BOX37_RS03745
uniprot id: A0A1J0VMG6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

2213200:BOX37 RS15650
gene id: 2213200:BOX37_RS15650
uniprot id: A0A1J0VSU2
names: Subcellular Location Annotation
messages: Membrane

2213200:BOX37 RS32125
gene id: 2213200:BOX37_RS32125
uniprot id: A0A1J0W0D0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

2213200:BOX37 RS13460
gene id: 2213200:BOX37_RS13460
uniprot id: A0A1J0VRV2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

2213200:BOX37 RS03955
gene id: 2213200:BOX37_RS03955
uniprot id: A0A1J0W109
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

2213200:BOX37 RS15500
gene id: 2213200:BOX37_RS15500
uniprot id: A0A1J0VSS9
names: Subcellular Location Annotation
messages: Membrane

2213200:BOX37 RS24655
gene id: 2213200:BOX37_RS24655
uniprot id: A0A1J0VWX2
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

2213200:BOX37 RS26275
gene id: 2213200:BOX37_RS26275
uniprot id: A0A1J0VXP6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2213200:BOX37 RS00595
gene id: 2213200:BOX37_RS00595
uniprot id: A0A1J0VL38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

2213200:BOX37 RS12710
gene id: 2213200:BOX37_RS12710
uniprot id: A0A1J0VRJ3
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

2213200:BOX37 RS04160
gene id: 2213200:BOX37_RS04160
uniprot id: A0A1J0VMR3
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. Nitrilase family.

2213200:BOX37 RS13195
gene id: 2213200:BOX37_RS13195
uniprot id: A0A1J0VRT4
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

2213200:BOX37 RS29165
gene id: 2213200:BOX37_RS29165
uniprot id: A0A1J0VZ12
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

2213200:BOX37 RS21200
gene id: 2213200:BOX37_RS21200
uniprot id: A0A1J0VVF8
names: Similarity
messages: Belongs to the YciI family.

2213200:BOX37 RS29790
gene id: 2213200:BOX37_RS29790
uniprot id: A0A1J0VZB2
names: Subcellular Location Annotation
messages: Membrane

2213200:BOX37 RS23970
gene id: 2213200:BOX37_RS23970
uniprot id: A0A1J0VWW2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

2213200:BOX37 RS09590
gene id: 2213200:BOX37_RS09590
uniprot id: A0A1J0VQ26
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

2213200:BOX37 RS09960
gene id: 2213200:BOX37_RS09960
uniprot id: A0A1J0W1I5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-3 family.
messages: Cytoplasm
messages: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
messages: Monomer.

2213200:BOX37 RS09150
gene id: 2213200:BOX37_RS09150
uniprot id: A0A1J0VQ07
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2213200:BOX37 RS09345
gene id: 2213200:BOX37_RS09345
uniprot id: A0A1J0W1F8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

2213200:BOX37 RS23245
gene id: 2213200:BOX37_RS23245
uniprot id: A0A1J0VW86
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ETF beta-subunit/FixA family.
messages: Heterodimer of an alpha and a beta subunit.
messages: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

2213200:BOX37 RS08600
gene id: 2213200:BOX37_RS08600
uniprot id: A0A1J0VPP0
names: Similarity
messages: Belongs to the DNA photolyase family.

2213200:BOX37 RS16825
gene id: 2213200:BOX37_RS16825
uniprot id: A0A1J0VTD6
names: Similarity
names: Subunit
messages: Belongs to the thiolase-like superfamily. Chalcone/stilbene synthases family.
messages: Homodimer.

2213200:BOX37 RS22665
gene id: 2213200:BOX37_RS22665
uniprot id: A0A1J0VVZ2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2213200:BOX37 RS03950
gene id: 2213200:BOX37_RS03950
uniprot id: A0A1J0VMM3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

2213200:BOX37 RS08450
gene id: 2213200:BOX37_RS08450
uniprot id: A0A1J0VPN6
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

2213200:BOX37 RS00050
gene id: 2213200:BOX37_RS00050
uniprot id: A0A1J0VKU8
names: Similarity
messages: Belongs to the F420H(2)-dependent quinone reductase family.

2213200:BOX37 RS15720
gene id: 2213200:BOX37_RS15720
uniprot id: A0A1J0VT58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

2213200:BOX37 RS11445
gene id: 2213200:BOX37_RS11445
uniprot id: A0A1J0VR67
names: Similarity
messages: Belongs to the peptidase S33 family.

2213200:BOX37 RS15405
gene id: 2213200:BOX37_RS15405
uniprot id: A0A1J0VSR0
names: Cofactor
names: Function
messages: Binds 1 [3Fe-4S] cluster.
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

2213200:BOX37 RS31085
gene id: 2213200:BOX37_RS31085
uniprot id: A0A1J0VZR8
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2213200:BOX37 RS15560
gene id: 2213200:BOX37_RS15560
uniprot id: A0A1J0W268
names: Similarity
messages: Belongs to the acyl-CoA oxidase family.

2213200:BOX37 RS22490
gene id: 2213200:BOX37_RS22490
uniprot id: A0A1J0VVW3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2213200:BOX37 RS05345
gene id: 2213200:BOX37_RS05345
uniprot id: A0A1J0VN95
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

2213200:BOX37 RS10000
gene id: 2213200:BOX37_RS10000
uniprot id: A0A1J0VQI6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

2213200:BOX37 RS10525
gene id: 2213200:BOX37_RS10525
uniprot id: A0A1J0VQJ2
names: Similarity
messages: Belongs to the AlaDH/PNT family.

2213200:BOX37 RS32055
gene id: 2213200:BOX37_RS32055
uniprot id: A0A1J0W3M2
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2213200:BOX37 RS25695
gene id: 2213200:BOX37_RS25695
uniprot id: A0A1J0VXF5
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

2213200:BOX37 RS11655
gene id: 2213200:BOX37_RS11655
uniprot id: A0A1J0VR26
names: Domain
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic ubiquitin-like protein family.
messages: Is modified by deamidation of its C-terminal glutamine to glutamate by the deamidase Dop, a prerequisite to the subsequent pupylation process.
messages: Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation.
messages: Strongly interacts with the proteasome-associated ATPase ARC through a hydrophobic interface; the interacting region of Pup lies in its C-terminal half. There is one Pup binding site per ARC hexamer ring.
messages: The N-terminal unstructured half of Pup provides a signal required to initiate unfolding and degradation by the proteasome but is not needed for pupylation, while the C-terminal helical half of Pup interacts with ARC to target proteins to the proteasome.

2213200:BOX37 RS24130
gene id: 2213200:BOX37_RS24130
uniprot id: A0A1J0VWR1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

2213200:BOX37 RS26415
gene id: 2213200:BOX37_RS26415
uniprot id: A0A1J0VXR6
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

2213200:BOX37 RS04125
gene id: 2213200:BOX37_RS04125
uniprot id: A0A1J0VMM8
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

2213200:BOX37 RS19995
gene id: 2213200:BOX37_RS19995
uniprot id: A0A1J0VUS0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glutaminase PdxT/SNO family.
messages: Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.
messages: In the presence of PdxS, forms a dodecamer of heterodimers. Only shows activity in the heterodimer.

2213200:BOX37 RS16890
gene id: 2213200:BOX37_RS16890
uniprot id: A0A1J0VTF6
names: Similarity
messages: Belongs to the AccD/PCCB family.

2213200:BOX37 RS24260
gene id: 2213200:BOX37_RS24260
uniprot id: A0A1J0VWM9
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

2213200:BOX37 RS08910
gene id: 2213200:BOX37_RS08910
uniprot id: A0A1J0VPX2
names: Similarity
messages: Belongs to the asparagine synthetase family.

2213200:BOX37 RS01995
gene id: 2213200:BOX37_RS01995
uniprot id: A0A1J0W110
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Catalyzes the reversible hydration of carbon dioxide to form bicarbonate.

2213200:BOX37 RS19240
gene id: 2213200:BOX37_RS19240
uniprot id: A0A1J0VUT3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 2 subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

2213200:BOX37 RS20350
gene id: 2213200:BOX37_RS20350
uniprot id: A0A1J0VV33
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

2213200:BOX37 RS14325
gene id: 2213200:BOX37_RS14325
uniprot id: A0A1J0VS82
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

2213200:BOX37 RS06685
gene id: 2213200:BOX37_RS06685
uniprot id: A0A1J0VNV2
names: Similarity
messages: Belongs to the XFP family.

2213200:BOX37 RS32375
gene id: 2213200:BOX37_RS32375
uniprot id: A0A1J0W0Q1
names: Similarity
messages: Belongs to the OsmC/Ohr family.

2213200:BOX37 RS01355
gene id: 2213200:BOX37_RS01355
uniprot id: A0A1J0VLE1
names: Subcellular Location Annotation
messages: Membrane

2213200:BOX37 RS09210
gene id: 2213200:BOX37_RS09210
uniprot id: A0A1J0VQ04
names: Similarity
messages: Belongs to the YggT family.

2213200:BOX37 RS01635
gene id: 2213200:BOX37_RS01635
uniprot id: A0A1J0W0R4
names: Subcellular Location Annotation
messages: Membrane

2213200:BOX37 RS03910
gene id: 2213200:BOX37_RS03910
uniprot id: A0A1J0VMJ4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

2213200:BOX37 RS22150
gene id: 2213200:BOX37_RS22150
uniprot id: A0A1J0VVT5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

2213200:BOX37 RS21575
gene id: 2213200:BOX37_RS21575
uniprot id: A0A1J0VVG1
names: Subcellular Location Annotation
messages: Membrane

2213200:BOX37 RS15045
gene id: 2213200:BOX37_RS15045
uniprot id: A0A1J0VSK2
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

2213200:BOX37 RS20905
gene id: 2213200:BOX37_RS20905
uniprot id: A0A1J0VVH2
names: Similarity
messages: Belongs to the 4-oxalocrotonate tautomerase family.

2213200:BOX37 RS20100
gene id: 2213200:BOX37_RS20100
uniprot id: A0A1J0W2N9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Catalyzes the reversible hydration of carbon dioxide to form bicarbonate.
messages: Membrane

2213200:BOX37 RS19855
gene id: 2213200:BOX37_RS19855
uniprot id: A0A1J0VUQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

2213200:BOX37 RS19040
gene id: 2213200:BOX37_RS19040
uniprot id: A0A1J0VUG6
names: Similarity
messages: Belongs to the peptidase C40 family.

2213200:BOX37 RS10375
gene id: 2213200:BOX37_RS10375
uniprot id: A0A1J0VQH3
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

2213200:BOX37 RS18630
gene id: 2213200:BOX37_RS18630
uniprot id: A0A1J0VU63
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

2213200:BOX37 RS03300
gene id: 2213200:BOX37_RS03300
uniprot id: A0A1J0VM91
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: Could possibly oxidize fatty acids using specific components.

2213200:BOX37 RS11710
gene id: 2213200:BOX37_RS11710
uniprot id: A0A1J0VR17
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

2213200:BOX37 RS12445
gene id: 2213200:BOX37_RS12445
uniprot id: A0A1J0VRH2
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

2213200:BOX37 RS32105
gene id: 2213200:BOX37_RS32105
uniprot id: A0A1J0W0C4
names: Subcellular Location Annotation
messages: Membrane

2213200:BOX37 RS02870
gene id: 2213200:BOX37_RS02870
uniprot id: A0A1J0VM34
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

2213200:BOX37 RS05015
gene id: 2213200:BOX37_RS05015
uniprot id: A0A1J0W1H6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PNT beta subunit family.
messages: Cell inner membrane
messages: Membrane
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

2213200:BOX37 RS06980
gene id: 2213200:BOX37_RS06980
uniprot id: A0A1J0VNX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

2213200:BOX37 RS18495
gene id: 2213200:BOX37_RS18495
uniprot id: A0A1J0VU78
names: Similarity
messages: Belongs to the TfdA dioxygenase family.

2213200:BOX37 RS04105
gene id: 2213200:BOX37_RS04105
uniprot id: A0A1J0VMP3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

2213200:BOX37 RS18775
gene id: 2213200:BOX37_RS18775
uniprot id: A0A1J0VU91
names: Subunit
messages: Heterodimer of an alpha and a beta chain.

2213200:BOX37 RS22480
gene id: 2213200:BOX37_RS22480
uniprot id: A0A1J0VW09
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

2213200:BOX37 RS11860
gene id: 2213200:BOX37_RS11860
uniprot id: A0A1J0VR58
names: Similarity
messages: Belongs to the acetaldehyde dehydrogenase family.

2213200:BOX37 RS12795
gene id: 2213200:BOX37_RS12795
uniprot id: A0A1J0VRM2
names: Similarity
names: Subunit
messages: Belongs to the glutaminase family.
messages: Homotetramer.

2213200:BOX37 RS05385
gene id: 2213200:BOX37_RS05385
uniprot id: A0A1J0VNB9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

2213200:BOX37 RS13725
gene id: 2213200:BOX37_RS13725
uniprot id: A0A1J0VS06
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20 family.
messages: Binds 2 Zn(2+) ions per subunit.

2213200:BOX37 RS20325
gene id: 2213200:BOX37_RS20325
uniprot id: A0A1J0VV11
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

2213200:BOX37 RS07945
gene id: 2213200:BOX37_RS07945
uniprot id: A0A1J0VPD7
names: Similarity
messages: Belongs to the AccD/PCCB family.

2213200:BOX37 RS07185
gene id: 2213200:BOX37_RS07185
uniprot id: A0A1J0VP24
names: Subcellular Location Annotation
messages: Membrane

2213200:BOX37 RS24545
gene id: 2213200:BOX37_RS24545
uniprot id: A0A1J0VWV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
messages: Membrane

2213200:BOX37 RS32610
gene id: 2213200:BOX37_RS32610
uniprot id: A0A1J0W0M3
names: Similarity
messages: Belongs to the HSP15 family.

2213200:BOX37 RS16835
gene id: 2213200:BOX37_RS16835
uniprot id: A0A1J0VTM8
names: Similarity
messages: Belongs to the LppX/LprAFG lipoprotein family.

2213200:BOX37 RS27490
gene id: 2213200:BOX37_RS27490
uniprot id: A0A1J0VY72
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. EgtE subfamily.
messages: Probably catalyzes the conversion of hercynylcysteine sulfoxide to ergothioneine.

2213200:BOX37 RS25280
gene id: 2213200:BOX37_RS25280
uniprot id: A0A1J0VXG2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. DeaD/CsdA subfamily.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation.

2213200:BOX37 RS21700
gene id: 2213200:BOX37_RS21700
uniprot id: A0A1J0VVK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

2213200:BOX37 RS02355
gene id: 2213200:BOX37_RS02355
uniprot id: A0A1J0VLW4
names: Similarity
messages: Belongs to the cytochrome P450 family.

2213200:BOX37 RS01775
gene id: 2213200:BOX37_RS01775
uniprot id: A0A1J0VLL3
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

2213200:BOX37 RS33045
gene id: 2213200:BOX37_RS33045
uniprot id: A0A1J0W3P9
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

2213200:BOX37 RS26375
gene id: 2213200:BOX37_RS26375
uniprot id: A0A1J0VXZ9
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

2213200:BOX37 RS11235
gene id: 2213200:BOX37_RS11235
uniprot id: A0A1J0VR35
names: Similarity
messages: Belongs to the UreD family.

2213200:BOX37 RS11660
gene id: 2213200:BOX37_RS11660
uniprot id: A0A1J0VR21
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
messages: Cytoplasm
messages: The 20S proteasome core is composed of 14 alpha and 14 beta subunits that assemble into four stacked heptameric rings, resulting in a barrel-shaped structure. The two inner rings, each composed of seven catalytic beta subunits, are sandwiched by two outer rings, each composed of seven alpha subunits. The catalytic chamber with the active sites is on the inside of the barrel. Has a gated structure, the ends of the cylinder being occluded by the N-termini of the alpha-subunits. Is capped by the proteasome-associated ATPase, ARC.
messages: The formation of the proteasomal ATPase ARC-20S proteasome complex, likely via the docking of the C-termini of ARC into the intersubunit pockets in the alpha-rings, may trigger opening of the gate for substrate entry. Interconversion between the open-gate and close-gate conformations leads to a dynamic regulation of the 20S proteasome proteolysis activity.

2213200:BOX37 RS05410
gene id: 2213200:BOX37_RS05410
uniprot id: A0A1J0VN71
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

2213200:BOX37 RS19895
gene id: 2213200:BOX37_RS19895
uniprot id: A0A1J0VUW0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvB family.
messages: Forms a complex with RuvA.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.

2213200:BOX37 RS21925
gene id: 2213200:BOX37_RS21925
uniprot id: A0A1J0VVS6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein S19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein S19.

2213200:BOX37 RS11945
gene id: 2213200:BOX37_RS11945
uniprot id: A0A1J0VR90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

2213200:BOX37 RS26280
gene id: 2213200:BOX37_RS26280
uniprot id: A0A1J0VXP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0073 (Hly-III) family.
messages: Membrane

2213200:BOX37 RS10265
gene id: 2213200:BOX37_RS10265
uniprot id: A0A1J0VQG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

2213200:BOX37 RS21745
gene id: 2213200:BOX37_RS21745
uniprot id: A0A1J0VVI7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

2213200:BOX37 RS25480
gene id: 2213200:BOX37_RS25480
uniprot id: A0A1J0VXJ6
names: Subcellular Location Annotation
messages: Membrane

2213200:BOX37 RS11530
gene id: 2213200:BOX37_RS11530
uniprot id: A0A1J0VR14
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Feedback inhibited by histidine.

2213200:BOX37 RS12015
gene id: 2213200:BOX37_RS12015
uniprot id: A0A1J0VR87
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

2213200:BOX37 RS21370
gene id: 2213200:BOX37_RS21370
uniprot id: A0A1J0VVF9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

2213200:BOX37 RS00780
gene id: 2213200:BOX37_RS00780
uniprot id: A0A1J0VL29
names: Similarity
messages: Belongs to the AccD/PCCB family.

2213200:BOX37 RS00960
gene id: 2213200:BOX37_RS00960
uniprot id: A0A1J0VL86
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

2213200:BOX37 RS12555
gene id: 2213200:BOX37_RS12555
uniprot id: A0A1J0VRH5
names: Function
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
messages: Catalyzes reversively the conversion of L-aspartate beta-semialdehyde (ASA) to L-2,4-diaminobutyrate (DABA) by transamination with L-glutamate.

2213200:BOX37 RS00320
gene id: 2213200:BOX37_RS00320
uniprot id: A0A1J0VKW8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class II aldolase/RraA-like family.
messages: Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2-oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions.
messages: Homotrimer.

2213200:BOX37 RS28380
gene id: 2213200:BOX37_RS28380
uniprot id: A0A1J0VYH4
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2213200:BOX37 RS07990
gene id: 2213200:BOX37_RS07990
uniprot id: A0A1J0VPG7
names: Similarity
names: Subunit
messages: Belongs to the sigma-70 factor family. ECF subfamily.
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

2213200:BOX37 RS14915
gene id: 2213200:BOX37_RS14915
uniprot id: A0A1J0VSH4
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

2213200:BOX37 RS06240
gene id: 2213200:BOX37_RS06240
uniprot id: A0A1J0VNM6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2213200:BOX37 RS20855
gene id: 2213200:BOX37_RS20855
uniprot id: A0A1J0W2L8
names: Similarity
messages: Belongs to the histone deacetylase family.

2213200:BOX37 RS25490
gene id: 2213200:BOX37_RS25490
uniprot id: A0A1J0VXC5
names: Similarity
names: Subunit
messages: Belongs to the sigma-70 factor family. ECF subfamily.
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

2213200:BOX37 RS14940
gene id: 2213200:BOX37_RS14940
uniprot id: A0A1J0VSI3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2213200:BOX37 RS23555
gene id: 2213200:BOX37_RS23555
uniprot id: A0A1J0VWH2
names: Subcellular Location Annotation
messages: Membrane

2213200:BOX37 RS02030
gene id: 2213200:BOX37_RS02030
uniprot id: A0A1J0VLP9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

2213200:BOX37 RS09760
gene id: 2213200:BOX37_RS09760
uniprot id: A0A1J0VQ87
names: Subcellular Location Annotation
messages: Membrane

2213200:BOX37 RS26085
gene id: 2213200:BOX37_RS26085
uniprot id: A0A1J0VXL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

2213200:BOX37 RS07170
gene id: 2213200:BOX37_RS07170
uniprot id: A0A1J0VP06
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

2213200:BOX37 RS21360
gene id: 2213200:BOX37_RS21360
uniprot id: A0A1J0VVH0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

2213200:BOX37 RS24265
gene id: 2213200:BOX37_RS24265
uniprot id: A0A1J0VWQ0
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

2213200:BOX37 RS19470
gene id: 2213200:BOX37_RS19470
uniprot id: A0A1J0VUI9
names: Similarity
messages: Belongs to the OMP decarboxylase family. Type 2 subfamily.

2213200:BOX37 RS27465
gene id: 2213200:BOX37_RS27465
uniprot id: A0A1J0VY44
names: Function
names: Similarity
names: Subunit
messages: Belongs to the methyltransferase superfamily. EgtD family.
messages: Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine.
messages: Monomer.

2213200:BOX37 RS01660
gene id: 2213200:BOX37_RS01660
uniprot id: A0A1J0VLK1
names: Subcellular Location Annotation
messages: Cytoplasm

2213200:BOX37 RS14435
gene id: 2213200:BOX37_RS14435
uniprot id: A0A1J0VSB6
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

2213200:BOX37 RS18980
gene id: 2213200:BOX37_RS18980
uniprot id: A0A1J0VUC4
names: Similarity
messages: Belongs to the band 7/mec-2 family.

2213200:BOX37 RS17830
gene id: 2213200:BOX37_RS17830
uniprot id: A0A1J0VTW6
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

2213200:BOX37 RS12825
gene id: 2213200:BOX37_RS12825
uniprot id: A0A1J0VRK8
names: Similarity
messages: Belongs to the YciI family.

2213200:BOX37 RS13200
gene id: 2213200:BOX37_RS13200
uniprot id: A0A1J0VRT0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

2213200:BOX37 RS24465
gene id: 2213200:BOX37_RS24465
uniprot id: A0A1J0VWV4
names: Similarity
messages: Belongs to the FAD-binding monooxygenase family.

2213200:BOX37 RS09040
gene id: 2213200:BOX37_RS09040
uniprot id: A0A1J0VPW3
names: Similarity
messages: Belongs to the class-II DAHP synthase family.

2213200:BOX37 RS04035
gene id: 2213200:BOX37_RS04035
uniprot id: A0A1J0VMM4
names: Similarity
messages: Belongs to the EspG family.

2213200:BOX37 RS32815
gene id: 2213200:BOX37_RS32815
uniprot id: A0A1J0W0V2
names: Similarity
messages: Belongs to the thioesterase family.

2213200:BOX37 RS02395
gene id: 2213200:BOX37_RS02395
uniprot id: A0A1J0VLW8
names: Similarity
names: Subunit
messages: Belongs to the sigma-70 factor family. ECF subfamily.
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

2213200:BOX37 RS11650
gene id: 2213200:BOX37_RS11650
uniprot id: A0A1J0VR12
names: Similarity
messages: Belongs to the Pup ligase/Pup deamidase family. Pup deamidase subfamily.

2213200:BOX37 RS07580
gene id: 2213200:BOX37_RS07580
uniprot id: A0A1J0VP85
names: Subcellular Location Annotation
messages: Membrane

2213200:BOX37 RS30115
gene id: 2213200:BOX37_RS30115
uniprot id: A0A1J0VZA2
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

2213200:BOX37 RS09225
gene id: 2213200:BOX37_RS09225
uniprot id: A0A1J0VPY0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

2213200:BOX37 RS31945
gene id: 2213200:BOX37_RS31945
uniprot id: A0A1J0W058
names: Similarity
messages: Belongs to the 6-phosphogluconate dehydrogenase family.

2213200:BOX37 RS19405
gene id: 2213200:BOX37_RS19405
uniprot id: A0A1J0VUN0
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

2213200:BOX37 RS24045
gene id: 2213200:BOX37_RS24045
uniprot id: A0A1J0VWJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

2213200:BOX37 RS15645
gene id: 2213200:BOX37_RS15645
uniprot id: A0A1J0VST1
names: Similarity
messages: Belongs to the peptidase S11 family.

2213200:BOX37 RS03180
gene id: 2213200:BOX37_RS03180
uniprot id: A0A1J0VM93
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2213200:BOX37 RS16240
gene id: 2213200:BOX37_RS16240
uniprot id: A0A1J0W245
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

2213200:BOX37 RS04950
gene id: 2213200:BOX37_RS04950
uniprot id: A0A1J0W1A4
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

2213200:BOX37 RS21090
gene id: 2213200:BOX37_RS21090
uniprot id: A0A1J0VVE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

2213200:BOX37 RS10640
gene id: 2213200:BOX37_RS10640
uniprot id: A0A1J0VQT6
names: Similarity
messages: Belongs to the AccD/PCCB family.

2213200:BOX37 RS25135
gene id: 2213200:BOX37_RS25135
uniprot id: A0A1J0W361
names: Similarity
messages: Belongs to the UPF0225 family.

2213200:BOX37 RS14010
gene id: 2213200:BOX37_RS14010
uniprot id: A0A1J0VSC6
names: Similarity
messages: Belongs to the universal stress protein A family.

2213200:BOX37 RS24435
gene id: 2213200:BOX37_RS24435
uniprot id: A0A1J0VWV3
names: Subcellular Location Annotation
messages: Membrane

2213200:BOX37 RS00025
gene id: 2213200:BOX37_RS00025
uniprot id: A0A1J0VKS1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

2213200:BOX37 RS21225
gene id: 2213200:BOX37_RS21225
uniprot id: A0A1J0VVE6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

2213200:BOX37 RS19865
gene id: 2213200:BOX37_RS19865
uniprot id: A0A1J0VUR6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

2213200:BOX37 RS09130
gene id: 2213200:BOX37_RS09130
uniprot id: A0A1J0W1L7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

2213200:BOX37 RS09435
gene id: 2213200:BOX37_RS09435
uniprot id: A0A1J0VQ19
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
messages: Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.
messages: Cytoplasm
messages: Homodimer.

2213200:BOX37 RS12150
gene id: 2213200:BOX37_RS12150
uniprot id: A0A1J0VRB8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2213200:BOX37 RS09280
gene id: 2213200:BOX37_RS09280
uniprot id: A0A1J0VQ75
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

2213200:BOX37 RS07600
gene id: 2213200:BOX37_RS07600
uniprot id: A0A1J0VPA0
names: Function
names: Similarity
messages: Belongs to the ApbE family.
messages: Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.

2213200:BOX37 RS24395
gene id: 2213200:BOX37_RS24395
uniprot id: A0A1J0VWT4
names: Function
names: Similarity
messages: Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).

2213200:BOX37 RS03365
gene id: 2213200:BOX37_RS03365
uniprot id: A0A1J0VMA5
names: Similarity
messages: Belongs to the adenylyl cyclase class-3 family.

2213200:BOX37 RS12355
gene id: 2213200:BOX37_RS12355
uniprot id: A0A1J0VRD6
names: Subcellular Location Annotation
messages: Membrane

2213200:BOX37 RS02200
gene id: 2213200:BOX37_RS02200
uniprot id: A0A1J0VLR4
names: Similarity
messages: Belongs to the extradiol ring-cleavage dioxygenase family.

2213200:BOX37 RS10300
gene id: 2213200:BOX37_RS10300
uniprot id: A0A1J0VQG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

2213200:BOX37 RS06800
gene id: 2213200:BOX37_RS06800
uniprot id: A0A1J0W1K9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

2213200:BOX37 RS32715
gene id: 2213200:BOX37_RS32715
uniprot id: A0A1J0W0V0
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

2213200:BOX37 RS13430
gene id: 2213200:BOX37_RS13430
uniprot id: A0A1J0W1Z9
names: Similarity
messages: In the N-terminal section; belongs to the CRISPR-associated nuclease Cas3-HD family.
messages: In the central section; belongs to the CRISPR-associated helicase Cas3 family.

2213200:BOX37 RS24835
gene id: 2213200:BOX37_RS24835
uniprot id: A0A1J0VX08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2213200:BOX37 RS31110
gene id: 2213200:BOX37_RS31110
uniprot id: A0A1J0VZW4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

2213200:BOX37 RS16535
gene id: 2213200:BOX37_RS16535
uniprot id: A0A1J0VT71
names: Subcellular Location Annotation
messages: Membrane

2213200:BOX37 RS04335
gene id: 2213200:BOX37_RS04335
uniprot id: A0A1J0VMQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AB hydrolase superfamily.
messages: Periplasm

2213200:BOX37 RS19175
gene id: 2213200:BOX37_RS19175
uniprot id: A0A1J0VUE2
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

2213200:BOX37 RS24125
gene id: 2213200:BOX37_RS24125
uniprot id: A0A1J0VWM7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

2213200:BOX37 RS17485
gene id: 2213200:BOX37_RS17485
uniprot id: A0A1J0VTM5
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

2213200:BOX37 RS07125
gene id: 2213200:BOX37_RS07125
uniprot id: A0A1J0VNZ8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.
messages: Cytoplasm

2213200:BOX37 RS08995
gene id: 2213200:BOX37_RS08995
uniprot id: A0A1J0VPV3
names: Similarity
messages: Belongs to the TrpF family.

2213200:BOX37 RS19605
gene id: 2213200:BOX37_RS19605
uniprot id: A0A1J0VUX7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm

2213200:BOX37 RS15370
gene id: 2213200:BOX37_RS15370
uniprot id: A0A1J0VSR9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2213200:BOX37 RS21785
gene id: 2213200:BOX37_RS21785
uniprot id: A0A1J0VVJ0
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

2213200:BOX37 RS26305
gene id: 2213200:BOX37_RS26305
uniprot id: A0A1J0VXR9
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

2213200:BOX37 RS13745
gene id: 2213200:BOX37_RS13745
uniprot id: A0A1J0VS02
names: Similarity
messages: Belongs to the glutamine synthetase family.

2213200:BOX37 RS28460
gene id: 2213200:BOX37_RS28460
uniprot id: A0A1J0VYR1
names: Similarity
messages: Belongs to the colicin/pyosin nuclease family.

2213200:BOX37 RS29825
gene id: 2213200:BOX37_RS29825
uniprot id: A0A1J0VZ65
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

2213200:BOX37 RS02090
gene id: 2213200:BOX37_RS02090
uniprot id: A0A1J0VLQ5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

2213200:BOX37 RS31220
gene id: 2213200:BOX37_RS31220
uniprot id: A0A1J0W067
names: Similarity
messages: Belongs to the band 7/mec-2 family. Flotillin subfamily.

2213200:BOX37 RS14750
gene id: 2213200:BOX37_RS14750
uniprot id: A0A1J0VSE9
names: Similarity
messages: Belongs to the prokaryotic/mitochondrial release factor family.

2213200:BOX37 RS21845
gene id: 2213200:BOX37_RS21845
uniprot id: A0A1J0VVJ9
names: Subcellular Location Annotation
messages: Membrane

2213200:BOX37 RS06500
gene id: 2213200:BOX37_RS06500
uniprot id: A0A1J0VNU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

2213200:BOX37 RS23400
gene id: 2213200:BOX37_RS23400
uniprot id: A0A1J0VW93
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
messages: Tetramer of two alpha and two beta subunits.

2213200:BOX37 RS03330
gene id: 2213200:BOX37_RS03330
uniprot id: A0A1J0VMB2
names: Subcellular Location Annotation
messages: Membrane

2213200:BOX37 RS03460
gene id: 2213200:BOX37_RS03460
uniprot id: A0A1J0VMB1
names: Subcellular Location Annotation
messages: Membrane

2213200:BOX37 RS21855
gene id: 2213200:BOX37_RS21855
uniprot id: A0A1J0W2R4
names: Similarity
messages: Belongs to the DprA/Smf family.

2213200:BOX37 RS01735
gene id: 2213200:BOX37_RS01735
uniprot id: A0A1J0VLK9
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

2213200:BOX37 RS29600
gene id: 2213200:BOX37_RS29600
uniprot id: A0A1J0VZ91
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

2213200:BOX37 RS12145
gene id: 2213200:BOX37_RS12145
uniprot id: A0A1J0VR84
names: Similarity
messages: Belongs to the MQO family.

2213200:BOX37 RS23860
gene id: 2213200:BOX37_RS23860
uniprot id: A0A1J0VWI8
names: Similarity
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.

2213200:BOX37 RS30865
gene id: 2213200:BOX37_RS30865
uniprot id: A0A1J0VZT1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

2213200:BOX37 RS21875
gene id: 2213200:BOX37_RS21875
uniprot id: A0A1J0W2R0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

2213200:BOX37 RS03140
gene id: 2213200:BOX37_RS03140
uniprot id: A0A1J0VM85
names: Similarity
messages: Belongs to the neutral ceramidase family.

2213200:BOX37 RS21085
gene id: 2213200:BOX37_RS21085
uniprot id: A0A1J0VV72
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

2213200:BOX37 RS18395
gene id: 2213200:BOX37_RS18395
uniprot id: A0A1J0VU46
names: Similarity
messages: Belongs to the CbbQ/NirQ/NorQ/GpvN family.

2213200:BOX37 RS29210
gene id: 2213200:BOX37_RS29210
uniprot id: A0A1J0VYW7
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

2213200:BOX37 RS10330
gene id: 2213200:BOX37_RS10330
uniprot id: A0A1J0VQE2
names: Subcellular Location Annotation
messages: Membrane

2213200:BOX37 RS09180
gene id: 2213200:BOX37_RS09180
uniprot id: A0A1J0VPX1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

2213200:BOX37 RS04205
gene id: 2213200:BOX37_RS04205
uniprot id: A0A1J0VMR8
names: Similarity
messages: Belongs to the EccD/Snm4 family.

2213200:BOX37 RS06695
gene id: 2213200:BOX37_RS06695
uniprot id: A0A1J0W166
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

2213200:BOX37 RS32940
gene id: 2213200:BOX37_RS32940
uniprot id: A0A1J0W0K6
names: Similarity
messages: Belongs to the peptidase M13 family.

2213200:BOX37 RS26970
gene id: 2213200:BOX37_RS26970
uniprot id: A0A1J0VXW6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

2213200:BOX37 RS16515
gene id: 2213200:BOX37_RS16515
uniprot id: A0A1J0VT83
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family. MbtB subfamily.

2213200:BOX37 RS15920
gene id: 2213200:BOX37_RS15920
uniprot id: A0A1J0VT09
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

2213200:BOX37 RS26965
gene id: 2213200:BOX37_RS26965
uniprot id: A0A1J0VXW5
names: Similarity
messages: Belongs to the EccE family.

2213200:BOX37 RS10165
gene id: 2213200:BOX37_RS10165
uniprot id: A0A1J0VQG4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

2213200:BOX37 RS18215
gene id: 2213200:BOX37_RS18215
uniprot id: A0A1J0W2F5
names: Subcellular Location Annotation
messages: Membrane

2213200:BOX37 RS16560
gene id: 2213200:BOX37_RS16560
uniprot id: A0A1J0VT76
names: Similarity
names: Subunit
messages: Belongs to the acetyltransferase Eis family.
messages: Homohexamer; trimer of dimers.

2213200:BOX37 RS32355
gene id: 2213200:BOX37_RS32355
uniprot id: A0A1J0W0C1
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

2213200:BOX37 RS04400
gene id: 2213200:BOX37_RS04400
uniprot id: A0A1J0VMS8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cell surface
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
messages: capsule
messages: cell wall

2213200:BOX37 RS15000
gene id: 2213200:BOX37_RS15000
uniprot id: A0A1J0VSU5
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

2213200:BOX37 RS17050
gene id: 2213200:BOX37_RS17050
uniprot id: A0A1J0VTF5
names: Similarity
messages: Belongs to the AHA1 family.

2213200:BOX37 RS08920
gene id: 2213200:BOX37_RS08920
uniprot id: A0A1J0VPU4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with subunits I, II and III to form cytochrome c oxidase.
messages: Belongs to the cytochrome c oxidase bacterial subunit CtaF family.
messages: Cell membrane
messages: Membrane
messages: Part of cytochrome c oxidase, its function is unknown.

2213200:BOX37 RS32180
gene id: 2213200:BOX37_RS32180
uniprot id: A0A1J0W0M0
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

2213200:BOX37 RS29430
gene id: 2213200:BOX37_RS29430
uniprot id: A0A1J0VZD6
names: Similarity
messages: Belongs to the AccD/PCCB family.

2213200:BOX37 RS12125
gene id: 2213200:BOX37_RS12125
uniprot id: A0A1J0VR96
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase-binding protein RbpA family.
messages: Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters.
messages: Forms a complex with the RNAP catalytic core and with free principal sigma factors.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2213200:BOX37 RS21850
gene id: 2213200:BOX37_RS21850
uniprot id: A0A1J0VVP1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

2213200:BOX37 RS01785
gene id: 2213200:BOX37_RS01785
uniprot id: A0A1J0VLK7
names: Similarity
messages: Belongs to the peptidase S13 family.

2213200:BOX37 RS21750
gene id: 2213200:BOX37_RS21750
uniprot id: A0A1J0VVM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

2213200:BOX37 RS01820
gene id: 2213200:BOX37_RS01820
uniprot id: A0A1J0VLJ9
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

2213200:BOX37 RS16210
gene id: 2213200:BOX37_RS16210
uniprot id: A0A1J0VT37
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

2213200:BOX37 RS20950
gene id: 2213200:BOX37_RS20950
uniprot id: A0A1J0VV97
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2213200:BOX37 RS14515
gene id: 2213200:BOX37_RS14515
uniprot id: A0A1J0VSA6
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

2213200:BOX37 RS16005
gene id: 2213200:BOX37_RS16005
uniprot id: A0A1J0VT07
names: Similarity
messages: Belongs to the FAD-binding monooxygenase family.

2213200:BOX37 RS02250
gene id: 2213200:BOX37_RS02250
uniprot id: A0A1J0VLU5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

2213200:BOX37 RS32615
gene id: 2213200:BOX37_RS32615
uniprot id: A0A1J0W0T4
names: Similarity
messages: Belongs to the peptidase C40 family.

2213200:BOX37 RS20170
gene id: 2213200:BOX37_RS20170
uniprot id: A0A1J0VUX2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2213200:BOX37 RS15110
gene id: 2213200:BOX37_RS15110
uniprot id: A0A1J0VSK3
names: Subcellular Location Annotation
messages: Membrane

2213200:BOX37 RS25080
gene id: 2213200:BOX37_RS25080
uniprot id: A0A1J0VX64
names: Subcellular Location Annotation
messages: Membrane

2213200:BOX37 RS15480
gene id: 2213200:BOX37_RS15480
uniprot id: A0A1J0VST4
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

2213200:BOX37 RS31470
gene id: 2213200:BOX37_RS31470
uniprot id: A0A1J0W0A5
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

2213200:BOX37 RS05665
gene id: 2213200:BOX37_RS05665
uniprot id: A0A1J0VND9
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

2213200:BOX37 RS19235
gene id: 2213200:BOX37_RS19235
uniprot id: A0A1J0VUI7
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Homodimer.

2213200:BOX37 RS33055
gene id: 2213200:BOX37_RS33055
uniprot id: A0A1J0W0M2
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

2213200:BOX37 RS24340
gene id: 2213200:BOX37_RS24340
uniprot id: A0A1J0VWT8
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

2213200:BOX37 RS25620
gene id: 2213200:BOX37_RS25620
uniprot id: A0A1J0VXC9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

2213200:BOX37 RS11245
gene id: 2213200:BOX37_RS11245
uniprot id: A0A1J0VQX5
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

2213200:BOX37 RS18725
gene id: 2213200:BOX37_RS18725
uniprot id: A0A1J0VUB9
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

2213200:BOX37 RS24300
gene id: 2213200:BOX37_RS24300
uniprot id: A0A1J0VWM0
names: Similarity
messages: Belongs to the transglycosylase family. Rpf subfamily.

2213200:BOX37 RS04770
gene id: 2213200:BOX37_RS04770
uniprot id: A0A1J0VMX2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: Homotrimer.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. Cleaves guanosine, inosine, 2'-deoxyguanosine and 2'-deoxyinosine.

2213200:BOX37 RS23190
gene id: 2213200:BOX37_RS23190
uniprot id: A0A1J0VW55
names: Subcellular Location Annotation
messages: Membrane

2213200:BOX37 RS09265
gene id: 2213200:BOX37_RS09265
uniprot id: A0A1J0VPZ2
names: Subcellular Location Annotation
messages: Cell membrane

2213200:BOX37 RS04170
gene id: 2213200:BOX37_RS04170
uniprot id: A0A1J0VMN4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
messages: Catalyzes the reversible phosphorylation of S-methyl-5'-thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.
messages: Homohexamer. Dimer of a homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2213200:BOX37 RS12535
gene id: 2213200:BOX37_RS12535
uniprot id: A0A1J0VRI6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

2213200:BOX37 RS26510
gene id: 2213200:BOX37_RS26510
uniprot id: A0A1J0VXS7
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

2213200:BOX37 RS12285
gene id: 2213200:BOX37_RS12285
uniprot id: A0A1J0VRK1
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

2213200:BOX37 RS10795
gene id: 2213200:BOX37_RS10795
uniprot id: A0A1J0VQQ2
names: Similarity
messages: Belongs to the HypD family.

2213200:BOX37 RS12420
gene id: 2213200:BOX37_RS12420
uniprot id: A0A1J0VRF0
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

2213200:BOX37 RS22195
gene id: 2213200:BOX37_RS22195
uniprot id: A0A1J0VVQ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

2213200:BOX37 RS19445
gene id: 2213200:BOX37_RS19445
uniprot id: A0A1J0VUW2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

2213200:BOX37 RS15180
gene id: 2213200:BOX37_RS15180
uniprot id: A0A1J0VSM4
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

2213200:BOX37 RS04870
gene id: 2213200:BOX37_RS04870
uniprot id: A0A1J0VMZ9
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

2213200:BOX37 RS13820
gene id: 2213200:BOX37_RS13820
uniprot id: A0A1J0VS09
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

2213200:BOX37 RS14720
gene id: 2213200:BOX37_RS14720
uniprot id: A0A1J0VSP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2213200:BOX37 RS01705
gene id: 2213200:BOX37_RS01705
uniprot id: A0A1J0W0U7
names: Similarity
messages: Belongs to the peptidase M1 family.

2213200:BOX37 RS11875
gene id: 2213200:BOX37_RS11875
uniprot id: A0A1J0VRD7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

2213200:BOX37 RS19300
gene id: 2213200:BOX37_RS19300
uniprot id: A0A1J0VUG2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

2213200:BOX37 RS12600
gene id: 2213200:BOX37_RS12600
uniprot id: A0A1J0W1X7
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

2213200:BOX37 RS09845
gene id: 2213200:BOX37_RS09845
uniprot id: A0A1J0VQ83
names: Similarity
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.

2213200:BOX37 RS09650
gene id: 2213200:BOX37_RS09650
uniprot id: A0A1J0VQ51
names: Similarity
messages: Belongs to the CdaR family.

2213200:BOX37 RS22065
gene id: 2213200:BOX37_RS22065
uniprot id: A0A1J0VVU7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

2213200:BOX37 RS26175
gene id: 2213200:BOX37_RS26175
uniprot id: A0A1J0VXJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2213200:BOX37 RS13280
gene id: 2213200:BOX37_RS13280
uniprot id: A0A1J0VRS8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the F420-dependent glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the coenzyme F420-dependent oxidation of glucose 6-phosphate (G6P) to 6-phosphogluconolactone.
messages: Homodimer.

2213200:BOX37 RS26190
gene id: 2213200:BOX37_RS26190
uniprot id: A0A1J0VXM6
names: Similarity
messages: Belongs to the FBPase class 2 family.

2213200:BOX37 RS08735
gene id: 2213200:BOX37_RS08735
uniprot id: A0A1J0VPR0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

2213200:BOX37 RS26990
gene id: 2213200:BOX37_RS26990
uniprot id: A0A1J0VY89
names: Similarity
messages: Belongs to the EspG family.

2213200:BOX37 RS04645
gene id: 2213200:BOX37_RS04645
uniprot id: A0A1J0VMY8
names: Subcellular Location Annotation
messages: Membrane

2213200:BOX37 RS16335
gene id: 2213200:BOX37_RS16335
uniprot id: A0A1J0VT73
names: Similarity
messages: Belongs to the universal stress protein A family.

2213200:BOX37 RS02760
gene id: 2213200:BOX37_RS02760
uniprot id: A0A1J0VM03
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

2213200:BOX37 RS30620
gene id: 2213200:BOX37_RS30620
uniprot id: A0A1J0W3V6
names: Similarity
messages: Belongs to the ATP-dependent DNA ligase family.

2213200:BOX37 RS03870
gene id: 2213200:BOX37_RS03870
uniprot id: A0A1J0VMI6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

2213200:BOX37 RS22190
gene id: 2213200:BOX37_RS22190
uniprot id: A0A1J0VVW1
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

2213200:BOX37 RS29120
gene id: 2213200:BOX37_RS29120
uniprot id: A0A1J0VYS5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

2213200:BOX37 RS11985
gene id: 2213200:BOX37_RS11985
uniprot id: A0A1J0VR60
names: Similarity
messages: Belongs to the extradiol ring-cleavage dioxygenase family.

2213200:BOX37 RS25400
gene id: 2213200:BOX37_RS25400
uniprot id: A0A1J0VXB3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

2213200:BOX37 RS11125
gene id: 2213200:BOX37_RS11125
uniprot id: A0A1J0VQR6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease gamma subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

2213200:BOX37 RS19210
gene id: 2213200:BOX37_RS19210
uniprot id: A0A1J0VUK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Membrane

2213200:BOX37 RS14825
gene id: 2213200:BOX37_RS14825
uniprot id: A0A1J0W246
names: Similarity
messages: Belongs to the cytochrome P450 family.

2213200:BOX37 RS22180
gene id: 2213200:BOX37_RS22180
uniprot id: A0A1J0VVV8
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

2213200:BOX37 RS31020
gene id: 2213200:BOX37_RS31020
uniprot id: A0A1J0VZM3
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

2213200:BOX37 RS01605
gene id: 2213200:BOX37_RS01605
uniprot id: A0A1J0VLI3
names: Caution
names: Function
names: PTM
names: Similarity
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2213200:BOX37 RS02655
gene id: 2213200:BOX37_RS02655
uniprot id: A0A1J0W0X5
names: Subcellular Location Annotation
messages: Membrane

2213200:BOX37 RS06375
gene id: 2213200:BOX37_RS06375
uniprot id: A0A1J0VNM1
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

2213200:BOX37 RS27645
gene id: 2213200:BOX37_RS27645
uniprot id: A0A1J0VY71
names: Subcellular Location Annotation
messages: Membrane

2213200:BOX37 RS11130
gene id: 2213200:BOX37_RS11130
uniprot id: A0A1J0VQT5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease beta subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

2213200:BOX37 RS09155
gene id: 2213200:BOX37_RS09155
uniprot id: A0A1J0VPX4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

2213200:BOX37 RS20145
gene id: 2213200:BOX37_RS20145
uniprot id: A0A1J0VV04
names: Subcellular Location Annotation
messages: Secreted

2213200:BOX37 RS06575
gene id: 2213200:BOX37_RS06575
uniprot id: A0A1J0VNR0
names: Similarity
messages: Belongs to the peptidase S14 family.

2213200:BOX37 RS05460
gene id: 2213200:BOX37_RS05460
uniprot id: A0A1J0VNB1
names: Cofactor
names: Similarity
messages: Belongs to the fatty acid desaturase type 2 family.
messages: Binds 2 iron ions per subunit.

2213200:BOX37 RS21560
gene id: 2213200:BOX37_RS21560
uniprot id: A0A1J0VVL6
names: Function
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.

2213200:BOX37 RS12365
gene id: 2213200:BOX37_RS12365
uniprot id: A0A1J0W1Q5
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

2213200:BOX37 RS20315
gene id: 2213200:BOX37_RS20315
uniprot id: A0A1J0VUY5
names: Similarity
messages: Belongs to the iron/ascorbate-dependent oxidoreductase family.

2213200:BOX37 RS07940
gene id: 2213200:BOX37_RS07940
uniprot id: A0A1J0VPF9
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

2213200:BOX37 RS15270
gene id: 2213200:BOX37_RS15270
uniprot id: A0A1J0VSM6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2213200:BOX37 RS12105
gene id: 2213200:BOX37_RS12105
uniprot id: A0A1J0W1Q1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

2213200:BOX37 RS18220
gene id: 2213200:BOX37_RS18220
uniprot id: A0A1J0VU41
names: Subcellular Location Annotation
messages: Membrane

2213200:BOX37 RS25860
gene id: 2213200:BOX37_RS25860
uniprot id: A0A1J0W357
names: Similarity
messages: Belongs to the LOG family.

2213200:BOX37 RS23085
gene id: 2213200:BOX37_RS23085
uniprot id: A0A1J0VW98
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system and for the release of the potassium ions to the cytoplasm.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

2213200:BOX37 RS22300
gene id: 2213200:BOX37_RS22300
uniprot id: A0A1J0VVS3
names: Similarity
messages: Belongs to the cytochrome P450 family.

2213200:BOX37 RS03720
gene id: 2213200:BOX37_RS03720
uniprot id: A0A1J0VMF6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

2213200:BOX37 RS01270
gene id: 2213200:BOX37_RS01270
uniprot id: A0A1J0VL97
names: Similarity
messages: Belongs to the DnaX/STICHEL family.

2213200:BOX37 RS04595
gene id: 2213200:BOX37_RS04595
uniprot id: A0A1J0VMY2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

2213200:BOX37 RS06710
gene id: 2213200:BOX37_RS06710
uniprot id: A0A1J0VNV3
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

2213200:BOX37 RS31120
gene id: 2213200:BOX37_RS31120
uniprot id: A0A1J0W051
names: Similarity
messages: Belongs to the F420H(2)-dependent quinone reductase family.

2213200:BOX37 RS30885
gene id: 2213200:BOX37_RS30885
uniprot id: A0A1J0VZJ7
names: Function
names: Similarity
messages: ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.
messages: Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.

2213200:BOX37 RS00005
gene id: 2213200:BOX37_RS00005
uniprot id: A0A1J0VKT1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

2213200:BOX37 RS18015
gene id: 2213200:BOX37_RS18015
uniprot id: A0A1J0VTW0
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2213200:BOX37 RS31380
gene id: 2213200:BOX37_RS31380
uniprot id: A0A1J0W015
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM86 family.
messages: Membrane

2213200:BOX37 RS03810
gene id: 2213200:BOX37_RS03810
uniprot id: A0A1J0VMJ8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

2213200:BOX37 RS10385
gene id: 2213200:BOX37_RS10385
uniprot id: A0A1J0VQH4
names: Similarity
messages: Belongs to the TlyA family.

2213200:BOX37 RS13065
gene id: 2213200:BOX37_RS13065
uniprot id: A0A1J0VRM7
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

2213200:BOX37 RS25055
gene id: 2213200:BOX37_RS25055
uniprot id: A0A1J0VX34
names: Cofactor
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 1 family.
messages: Binds 1 zinc ion per subunit.

2213200:BOX37 RS12120
gene id: 2213200:BOX37_RS12120
uniprot id: A0A1J0W1W4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

2213200:BOX37 RS28965
gene id: 2213200:BOX37_RS28965
uniprot id: A0A1J0VYS0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

2213200:BOX37 RS02705
gene id: 2213200:BOX37_RS02705
uniprot id: A0A1J0VM11
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

2213200:BOX37 RS21395
gene id: 2213200:BOX37_RS21395
uniprot id: A0A1J0VVI9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

2213200:BOX37 RS21295
gene id: 2213200:BOX37_RS21295
uniprot id: A0A1J0VVH5
names: Similarity
messages: Belongs to the peptidase M16 family.

2213200:BOX37 RS08075
gene id: 2213200:BOX37_RS08075
uniprot id: A0A1J0VPL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S33 family.
messages: Cytoplasm

2213200:BOX37 RS18475
gene id: 2213200:BOX37_RS18475
uniprot id: A0A1J0VU44
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

2213200:BOX37 RS19555
gene id: 2213200:BOX37_RS19555
uniprot id: A0A1J0VUX5
names: Similarity
messages: Belongs to the serpin family.

2213200:BOX37 RS01360
gene id: 2213200:BOX37_RS01360
uniprot id: A0A1J0VLB7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CobB/CobQ family. GatD subfamily.
messages: Forms a heterodimer with MurT.
messages: The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The GatD subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia. The resulting ammonia molecule is channeled to the active site of MurT.

2213200:BOX37 RS09735
gene id: 2213200:BOX37_RS09735
uniprot id: A0A1J0W1N7
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

2213200:BOX37 RS31355
gene id: 2213200:BOX37_RS31355
uniprot id: A0A1J0W3X0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

2213200:BOX37 RS29605
gene id: 2213200:BOX37_RS29605
uniprot id: A0A1J0VZ81
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

2213200:BOX37 RS00250
gene id: 2213200:BOX37_RS00250
uniprot id: A0A1J0VKY0
names: Similarity
messages: Belongs to the glutamate synthase family.

2213200:BOX37 RS25660
gene id: 2213200:BOX37_RS25660
uniprot id: A0A1J0VX93
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

2213200:BOX37 RS32160
gene id: 2213200:BOX37_RS32160
uniprot id: A0A1J0W089
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

2213200:BOX37 RS33115
gene id: 2213200:BOX37_RS33115
uniprot id: A0A1J0W115
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

2213200:BOX37 RS21930
gene id: 2213200:BOX37_RS21930
uniprot id: A0A1J0VVS4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: A probable RNA-binding protein.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm

2213200:BOX37 RS12255
gene id: 2213200:BOX37_RS12255
uniprot id: A0A1J0VRE0
names: Subcellular Location Annotation
messages: Membrane

2213200:BOX37 RS05310
gene id: 2213200:BOX37_RS05310
uniprot id: A0A1J0VN58
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

2213200:BOX37 RS01895
gene id: 2213200:BOX37_RS01895
uniprot id: A0A1J0VLM4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2213200:BOX37 RS32095
gene id: 2213200:BOX37_RS32095
uniprot id: A0A1J0W0I1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

2213200:BOX37 RS04100
gene id: 2213200:BOX37_RS04100
uniprot id: A0A1J0W165
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

2213200:BOX37 RS00410
gene id: 2213200:BOX37_RS00410
uniprot id: A0A1J0VKW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GDT1 family.
messages: Membrane

2213200:BOX37 RS25680
gene id: 2213200:BOX37_RS25680
uniprot id: A0A1J0VXN2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

2213200:BOX37 RS29100
gene id: 2213200:BOX37_RS29100
uniprot id: A0A1J0VYV2
names: Caution
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2213200:BOX37 RS28940
gene id: 2213200:BOX37_RS28940
uniprot id: A0A1J0VYP8
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

2213200:BOX37 RS20860
gene id: 2213200:BOX37_RS20860
uniprot id: A0A1J0VVB0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DtxR/MntR family.
messages: Cytoplasm
messages: Homodimer.

2213200:BOX37 RS32410
gene id: 2213200:BOX37_RS32410
uniprot id: A0A1J0W0C9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2213200:BOX37 RS35630
gene id: 2213200:BOX37_RS35630
uniprot id: A0A1J0VZ07
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

2213200:BOX37 RS06610
gene id: 2213200:BOX37_RS06610
uniprot id: A0A1J0VNU3
names: Similarity
messages: Belongs to the F420H(2)-dependent quinone reductase family.

2213200:BOX37 RS02885
gene id: 2213200:BOX37_RS02885
uniprot id: A0A1J0VM22
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

2213200:BOX37 RS06315
gene id: 2213200:BOX37_RS06315
uniprot id: A0A1J0VNP5
names: Subcellular Location Annotation
messages: Membrane

2213200:BOX37 RS22130
gene id: 2213200:BOX37_RS22130
uniprot id: A0A1J0VVV6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

2213200:BOX37 RS33105
gene id: 2213200:BOX37_RS33105
uniprot id: A0A1J0W0U5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

2213200:BOX37 RS15100
gene id: 2213200:BOX37_RS15100
uniprot id: A0A1J0VSK9
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

2213200:BOX37 RS19500
gene id: 2213200:BOX37_RS19500
uniprot id: A0A1J0VUP8
names: Function
names: Similarity
messages: Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
messages: Regulates the transcription of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines.

2213200:BOX37 RS09420
gene id: 2213200:BOX37_RS09420
uniprot id: A0A1J0VQ50
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

2213200:BOX37 RS10480
gene id: 2213200:BOX37_RS10480
uniprot id: A0A1J0VQI3
names: Similarity
messages: Belongs to the YggT family.

2213200:BOX37 RS29970
gene id: 2213200:BOX37_RS29970
uniprot id: A0A1J0VZL8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MenA family. Type 1 subfamily.
messages: Cell membrane
messages: Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK).
messages: Membrane

2213200:BOX37 RS03740
gene id: 2213200:BOX37_RS03740
uniprot id: A0A1J0VMG8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

2213200:BOX37 RS02800
gene id: 2213200:BOX37_RS02800
uniprot id: A0A1J0VM05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

2213200:BOX37 RS15220
gene id: 2213200:BOX37_RS15220
uniprot id: A0A1J0VSM0
names: Cofactor
messages: Binds 1 FAD per subunit.

2213200:BOX37 RS33060
gene id: 2213200:BOX37_RS33060
uniprot id: A0A1J0W0S8
names: Similarity
messages: Belongs to the thioredoxin family.

2213200:BOX37 RS21210
gene id: 2213200:BOX37_RS21210
uniprot id: A0A1J0W2X4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Essential cell division protein that coordinates cell division and chromosome segregation. The N-terminus is involved in assembly of the cell-division machinery. The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the dif recombination site, which is located within the replication terminus region. Required for activation of the Xer recombinase, allowing activation of chromosome unlinking by recombination.
messages: Membrane

2213200:BOX37 RS11775
gene id: 2213200:BOX37_RS11775
uniprot id: A0A1J0VR40
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

2213200:BOX37 RS00830
gene id: 2213200:BOX37_RS00830
uniprot id: A0A1J0VL73
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

2213200:BOX37 RS30870
gene id: 2213200:BOX37_RS30870
uniprot id: A0A1J0VZT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

2213200:BOX37 RS04730
gene id: 2213200:BOX37_RS04730
uniprot id: A0A1J0VMW2
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of adenosine and 2-deoxyadenosine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2213200:BOX37 RS06960
gene id: 2213200:BOX37_RS06960
uniprot id: A0A1J0VP00
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

2213200:BOX37 RS09510
gene id: 2213200:BOX37_RS09510
uniprot id: A0A1J0VQ25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

2213200:BOX37 RS11100
gene id: 2213200:BOX37_RS11100
uniprot id: A0A1J0VQT8
names: Similarity
messages: Belongs to the cytochrome P450 family.

2213200:BOX37 RS28200
gene id: 2213200:BOX37_RS28200
uniprot id: A0A1J0VYK2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

2213200:BOX37 RS02680
gene id: 2213200:BOX37_RS02680
uniprot id: A0A1J0VM02
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

2213200:BOX37 RS31925
gene id: 2213200:BOX37_RS31925
uniprot id: A0A1J0W023
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

2213200:BOX37 RS09620
gene id: 2213200:BOX37_RS09620
uniprot id: A0A1J0VQ64
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

2213200:BOX37 RS10390
gene id: 2213200:BOX37_RS10390
uniprot id: A0A1J0W1Y6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2213200:BOX37 RS07030
gene id: 2213200:BOX37_RS07030
uniprot id: A0A1J0VNY2
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

2213200:BOX37 RS11270
gene id: 2213200:BOX37_RS11270
uniprot id: A0A1J0VQX1
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD.
messages: Belongs to the RecD family.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding.

2213200:BOX37 RS15860
gene id: 2213200:BOX37_RS15860
uniprot id: A0A1J0VT82
names: Similarity
messages: Belongs to the universal stress protein A family.

2213200:BOX37 RS04750
gene id: 2213200:BOX37_RS04750
uniprot id: A0A1J0VMX7
names: Similarity
messages: Belongs to the peptidase C40 family.

2213200:BOX37 RS04795
gene id: 2213200:BOX37_RS04795
uniprot id: A0A1J0VMY7
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

2213200:BOX37 RS01275
gene id: 2213200:BOX37_RS01275
uniprot id: A0A1J0VLD5
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

2213200:BOX37 RS09260
gene id: 2213200:BOX37_RS09260
uniprot id: A0A1J0VPZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EamA transporter family.
messages: Membrane

2213200:BOX37 RS21045
gene id: 2213200:BOX37_RS21045
uniprot id: A0A1J0W2S6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2213200:BOX37 RS18580
gene id: 2213200:BOX37_RS18580
uniprot id: A0A1J0VU73
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

2213200:BOX37 RS03885
gene id: 2213200:BOX37_RS03885
uniprot id: A0A1J0VMH7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

2213200:BOX37 RS14735
gene id: 2213200:BOX37_RS14735
uniprot id: A0A1J0VSG0
names: Subcellular Location Annotation
messages: Membrane

2213200:BOX37 RS05940
gene id: 2213200:BOX37_RS05940
uniprot id: A0A1J0VNI1
names: Similarity
messages: Belongs to the universal stress protein A family.

2213200:BOX37 RS04425
gene id: 2213200:BOX37_RS04425
uniprot id: A0A1J0VMV0
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

2213200:BOX37 RS12250
gene id: 2213200:BOX37_RS12250
uniprot id: A0A1J0VRD4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

2213200:BOX37 RS22095
gene id: 2213200:BOX37_RS22095
uniprot id: A0A1J0W2V5
names: Function
messages: Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.

2213200:BOX37 RS09375
gene id: 2213200:BOX37_RS09375
uniprot id: A0A1J0VQ08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 13 family.
messages: Cytoplasm

2213200:BOX37 RS17275
gene id: 2213200:BOX37_RS17275
uniprot id: A0A1J0VTL1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Siderophore-Fe(3+) uptake transporter (SIUT) (TC 3.A.1.21) family.
messages: Cell inner membrane
messages: Forms a heterodimer with IrtB.

2213200:BOX37 RS24730
gene id: 2213200:BOX37_RS24730
uniprot id: A0A1J0VX07
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family. MbtB subfamily.

2213200:BOX37 RS11495
gene id: 2213200:BOX37_RS11495
uniprot id: A0A1J0VR02
names: Domain
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
messages: Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.

2213200:BOX37 RS13705
gene id: 2213200:BOX37_RS13705
uniprot id: A0A1J0VRZ0
names: Subcellular Location Annotation
messages: Membrane

2213200:BOX37 RS33100
gene id: 2213200:BOX37_RS33100
uniprot id: A0A1J0W0T3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

2213200:BOX37 RS17260
gene id: 2213200:BOX37_RS17260
uniprot id: A0A1J0VTM2
names: Similarity
messages: Belongs to the IucA/IucC family.

2213200:BOX37 RS10800
gene id: 2213200:BOX37_RS10800
uniprot id: A0A1J0VQK9
names: Similarity
messages: Belongs to the HypE family.

2213200:BOX37 RS20865
gene id: 2213200:BOX37_RS20865
uniprot id: A0A1J0VVB3
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

2213200:BOX37 RS09655
gene id: 2213200:BOX37_RS09655
uniprot id: A0A1J0VQ45
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRA-CH family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
messages: Cytoplasm
messages: Homodimer.

2213200:BOX37 RS15440
gene id: 2213200:BOX37_RS15440
uniprot id: A0A1J0W231
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acid desaturase type 1 family. AlkB subfamily.
messages: Cell inner membrane
messages: Membrane

2213200:BOX37 RS02445
gene id: 2213200:BOX37_RS02445
uniprot id: A0A1J0VLX0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

2213200:BOX37 RS30630
gene id: 2213200:BOX37_RS30630
uniprot id: A0A1J0VZI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

2213200:BOX37 RS07715
gene id: 2213200:BOX37_RS07715
uniprot id: A0A1J0VP96
names: Similarity
messages: Belongs to the F420H(2)-dependent quinone reductase family.

2213200:BOX37 RS24985
gene id: 2213200:BOX37_RS24985
uniprot id: A0A1J0VWZ4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

2213200:BOX37 RS21470
gene id: 2213200:BOX37_RS21470
uniprot id: A0A1J0VVR0
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

2213200:BOX37 RS26370
gene id: 2213200:BOX37_RS26370
uniprot id: A0A1J0VXQ8
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

2213200:BOX37 RS09635
gene id: 2213200:BOX37_RS09635
uniprot id: A0A1J0VQ33
names: Subcellular Location Annotation
messages: Membrane

2213200:BOX37 RS23535
gene id: 2213200:BOX37_RS23535
uniprot id: A0A1J0W339
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

2213200:BOX37 RS12345
gene id: 2213200:BOX37_RS12345
uniprot id: A0A1J0VRF6
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FBPase class 1 family.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2213200:BOX37 RS23475
gene id: 2213200:BOX37_RS23475
uniprot id: A0A1J0VWA9
names: Function
names: Similarity
messages: Belongs to the NrdI family.
messages: Probably involved in ribonucleotide reductase function.

2213200:BOX37 RS10980
gene id: 2213200:BOX37_RS10980
uniprot id: A0A1J0VQP1
names: Similarity
messages: Belongs to the SurE nucleotidase family.

2213200:BOX37 RS18040
gene id: 2213200:BOX37_RS18040
uniprot id: A0A1J0VTX0
names: Subcellular Location Annotation
messages: Membrane

2213200:BOX37 RS15125
gene id: 2213200:BOX37_RS15125
uniprot id: A0A1J0VSK6
names: Subcellular Location Annotation
messages: Membrane

2213200:BOX37 RS29800
gene id: 2213200:BOX37_RS29800
uniprot id: A0A1J0VZ24
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

2213200:BOX37 RS02255
gene id: 2213200:BOX37_RS02255
uniprot id: A0A1J0VLU2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

2213200:BOX37 RS06860
gene id: 2213200:BOX37_RS06860
uniprot id: A0A1J0VNV7
names: Cofactor
names: Similarity
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.

2213200:BOX37 RS23545
gene id: 2213200:BOX37_RS23545
uniprot id: A0A1J0VWN7
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

2213200:BOX37 RS31580
gene id: 2213200:BOX37_RS31580
uniprot id: A0A1J0VZZ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate.
messages: Homotrimer.

2213200:BOX37 RS00125
gene id: 2213200:BOX37_RS00125
uniprot id: A0A1J0VKV8
names: Subcellular Location Annotation
messages: Membrane

2213200:BOX37 RS09485
gene id: 2213200:BOX37_RS09485
uniprot id: A0A1J0VQ46
names: Function
messages: TetR is the repressor of the tetracycline resistance element; its N-terminal region forms a helix-turn-helix structure and binds DNA. Binding of tetracycline to TetR reduces the repressor affinity for the tetracycline resistance gene (tetA) promoter operator sites.

2213200:BOX37 RS03775
gene id: 2213200:BOX37_RS03775
uniprot id: A0A1J0VMI8
names: Subcellular Location Annotation
messages: Membrane

2213200:BOX37 RS19275
gene id: 2213200:BOX37_RS19275
uniprot id: A0A1J0W2U6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

2213200:BOX37 RS01130
gene id: 2213200:BOX37_RS01130
uniprot id: A0A1J0VLA7
names: Subcellular Location Annotation
messages: Membrane

2213200:BOX37 RS04900
gene id: 2213200:BOX37_RS04900
uniprot id: A0A1J0VN14
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

2213200:BOX37 RS04560
gene id: 2213200:BOX37_RS04560
uniprot id: A0A1J0VMU5
names: Subcellular Location Annotation
messages: Membrane

2213200:BOX37 RS17530
gene id: 2213200:BOX37_RS17530
uniprot id: A0A1J0VTZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

2213200:BOX37 RS22230
gene id: 2213200:BOX37_RS22230
uniprot id: A0A1J0VVQ1
names: Subcellular Location Annotation
messages: Membrane

2213200:BOX37 RS30640
gene id: 2213200:BOX37_RS30640
uniprot id: A0A1J0VZP4
names: Subcellular Location Annotation
messages: Membrane

2213200:BOX37 RS30275
gene id: 2213200:BOX37_RS30275
uniprot id: A0A1J0VZJ0
names: Subcellular Location Annotation
messages: Membrane

2213200:BOX37 RS02450
gene id: 2213200:BOX37_RS02450
uniprot id: A0A1J0VLV6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

2213200:BOX37 RS08250
gene id: 2213200:BOX37_RS08250
uniprot id: A0A1J0VPL0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glutamine synthetase family.
messages: Cytoplasm
messages: Oligomer of 12 subunits arranged in the form of two hexagons.

2213200:BOX37 RS19650
gene id: 2213200:BOX37_RS19650
uniprot id: A0A1J0VUY1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

2213200:BOX37 RS15895
gene id: 2213200:BOX37_RS15895
uniprot id: A0A1J0VSZ1
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

2213200:BOX37 RS03710
gene id: 2213200:BOX37_RS03710
uniprot id: A0A1J0VMG3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

2213200:BOX37 RS07095
gene id: 2213200:BOX37_RS07095
uniprot id: A0A1J0VNZ6
names: Subcellular Location Annotation
messages: Membrane

2213200:BOX37 RS30890
gene id: 2213200:BOX37_RS30890
uniprot id: A0A1J0VZX2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Cu-Zn superoxide dismutase family.
messages: Binds 1 copper ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems. May play a role in favoring mycobacterial survival in phagocytes.

2213200:BOX37 RS24285
gene id: 2213200:BOX37_RS24285
uniprot id: A0A1J0VWR7
names: Subcellular Location Annotation
messages: Membrane

2213200:BOX37 RS25800
gene id: 2213200:BOX37_RS25800
uniprot id: A0A1J0VXC6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
messages: Homotetramer.
messages: Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.

2213200:BOX37 RS09035
gene id: 2213200:BOX37_RS09035
uniprot id: A0A1J0W1L0
names: Cofactor
names: Function
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Exonuclease that cleaves single-stranded 3' overhangs of double-stranded RNA.
messages: Homodimer.

2213200:BOX37 RS11085
gene id: 2213200:BOX37_RS11085
uniprot id: A0A1J0VQS8
names: Similarity
messages: Belongs to the cytochrome P450 family.

2213200:BOX37 RS01570
gene id: 2213200:BOX37_RS01570
uniprot id: A0A1J0W100
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

2213200:BOX37 RS15835
gene id: 2213200:BOX37_RS15835
uniprot id: A0A1J0VSZ5
names: Similarity
messages: Belongs to the peptidase C56 family.

2213200:BOX37 RS16185
gene id: 2213200:BOX37_RS16185
uniprot id: A0A1J0VT54
names: Similarity
messages: Belongs to the UPF0098 family.

2213200:BOX37 RS26685
gene id: 2213200:BOX37_RS26685
uniprot id: A0A1J0VXY1
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

2213200:BOX37 RS15825
gene id: 2213200:BOX37_RS15825
uniprot id: A0A1J0VSW3
names: Similarity
messages: Belongs to the peptidase M1 family.

2213200:BOX37 RS26525
gene id: 2213200:BOX37_RS26525
uniprot id: A0A1J0W370
names: Similarity
messages: Belongs to the Nudix hydrolase family.

2213200:BOX37 RS22055
gene id: 2213200:BOX37_RS22055
uniprot id: A0A1J0VVM5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

2213200:BOX37 RS25925
gene id: 2213200:BOX37_RS25925
uniprot id: A0A1J0VXK0
names: Cofactor
names: Function
messages: Binds 1 [3Fe-4S] cluster.
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

2213200:BOX37 RS16510
gene id: 2213200:BOX37_RS16510
uniprot id: A0A1J0VT80
names: Similarity
messages: Belongs to the CdaR family.

2213200:BOX37 RS18310
gene id: 2213200:BOX37_RS18310
uniprot id: A0A1J0VUB6
names: Similarity
messages: Belongs to the universal stress protein A family.

2213200:BOX37 RS05890
gene id: 2213200:BOX37_RS05890
uniprot id: A0A1J0VNF7
names: Similarity
messages: Belongs to the phosphate/phosphite/phosphonate binding protein family.

2213200:BOX37 RS11415
gene id: 2213200:BOX37_RS11415
uniprot id: A0A1J0VQW6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I fumarase family.
messages: Catalyzes the reversible hydration of fumarate to (S)-malate.
messages: Homodimer.

2213200:BOX37 RS01585
gene id: 2213200:BOX37_RS01585
uniprot id: A0A1J0VLH8
names: Subcellular Location Annotation
messages: Membrane

2213200:BOX37 RS09540
gene id: 2213200:BOX37_RS09540
uniprot id: A0A1J0W1U3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate, the first step in the de novo biosynthesis of NAD(+).
messages: Cytoplasm

2213200:BOX37 RS21405
gene id: 2213200:BOX37_RS21405
uniprot id: A0A1J0VVD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

2213200:BOX37 RS09950
gene id: 2213200:BOX37_RS09950
uniprot id: A0A1J0VQ88
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

2213200:BOX37 RS20000
gene id: 2213200:BOX37_RS20000
uniprot id: A0A1J0VUX9
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

2213200:BOX37 RS31035
gene id: 2213200:BOX37_RS31035
uniprot id: A0A1J0VZQ9
names: Similarity
messages: Belongs to the AccD/PCCB family.

2213200:BOX37 RS04610
gene id: 2213200:BOX37_RS04610
uniprot id: A0A1J0VMW0
names: Similarity
messages: Belongs to the ribonuclease N1/T1 family.

2213200:BOX37 RS29275
gene id: 2213200:BOX37_RS29275
uniprot id: A0A1J0W3E8
names: Subcellular Location Annotation
messages: Membrane

2213200:BOX37 RS25105
gene id: 2213200:BOX37_RS25105
uniprot id: A0A1J0VX62
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

2213200:BOX37 RS15815
gene id: 2213200:BOX37_RS15815
uniprot id: A0A1J0VSX2
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

2213200:BOX37 RS22380
gene id: 2213200:BOX37_RS22380
uniprot id: A0A1J0W2S4
names: Similarity
messages: Belongs to the cytochrome P450 family.

2213200:BOX37 RS05100
gene id: 2213200:BOX37_RS05100
uniprot id: A0A1J0VN65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

2213200:BOX37 RS05960
gene id: 2213200:BOX37_RS05960
uniprot id: A0A1J0VNI7
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family. MbtB subfamily.

2213200:BOX37 RS22020
gene id: 2213200:BOX37_RS22020
uniprot id: A0A1J0W2S0
names: Similarity
messages: Belongs to the acylphosphatase family.

2213200:BOX37 RS01530
gene id: 2213200:BOX37_RS01530
uniprot id: A0A1J0VLG4
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

2213200:BOX37 RS09815
gene id: 2213200:BOX37_RS09815
uniprot id: A0A1J0VQ60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2213200:BOX37 RS20275
gene id: 2213200:BOX37_RS20275
uniprot id: A0A1J0VV84
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

2213200:BOX37 RS30810
gene id: 2213200:BOX37_RS30810
uniprot id: A0A1J0VZL9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

2213200:BOX37 RS18225
gene id: 2213200:BOX37_RS18225
uniprot id: A0A1J0VTZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family. Mmr subfamily.
messages: Cell membrane
messages: Membrane

2213200:BOX37 RS14025
gene id: 2213200:BOX37_RS14025
uniprot id: A0A1J0VS63
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

2213200:BOX37 RS10430
gene id: 2213200:BOX37_RS10430
uniprot id: A0A1J0VQI5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

2213200:BOX37 RS04120
gene id: 2213200:BOX37_RS04120
uniprot id: A0A1J0VMM7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

2213200:BOX37 RS23255
gene id: 2213200:BOX37_RS23255
uniprot id: A0A1J0VWA5
names: Similarity
messages: Belongs to the glycosyl hydrolase 57 family.

2213200:BOX37 RS33075
gene id: 2213200:BOX37_RS33075
uniprot id: A0A1J0W0J9
names: Similarity
messages: Belongs to the ParB family.

2213200:BOX37 RS01395
gene id: 2213200:BOX37_RS01395
uniprot id: A0A1J0VLE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

2213200:BOX37 RS19495
gene id: 2213200:BOX37_RS19495
uniprot id: A0A1J0VUJ2
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

2213200:BOX37 RS25470
gene id: 2213200:BOX37_RS25470
uniprot id: A0A1J0VXC2
names: Subcellular Location Annotation
messages: Membrane

2213200:BOX37 RS09880
gene id: 2213200:BOX37_RS09880
uniprot id: A0A1J0VQB7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the UPF0157 (GrpB) family.
messages: In the N-terminal section; belongs to the CoaE family.

2213200:BOX37 RS19050
gene id: 2213200:BOX37_RS19050
uniprot id: A0A1J0VUI2
names: Function
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.

2213200:BOX37 RS09215
gene id: 2213200:BOX37_RS09215
uniprot id: A0A1J0VQ66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DivIVA family.
messages: Cytoplasm

2213200:BOX37 RS04440
gene id: 2213200:BOX37_RS04440
uniprot id: A0A1J0W114
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

2213200:BOX37 RS03635
gene id: 2213200:BOX37_RS03635
uniprot id: A0A1J0VME7
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family. MbtB subfamily.

2213200:BOX37 RS20095
gene id: 2213200:BOX37_RS20095
uniprot id: A0A1J0VUZ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Catalyzes the reversible hydration of carbon dioxide to form bicarbonate.
messages: Membrane

2213200:BOX37 RS25520
gene id: 2213200:BOX37_RS25520
uniprot id: A0A1J0VXK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2213200:BOX37 RS20580
gene id: 2213200:BOX37_RS20580
uniprot id: A0A1J0VV71
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protoporphyrinogen/coproporphyrinogen oxidase family. Coproporphyrinogen III oxidase subfamily.
messages: Cytoplasm
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the oxidation of coproporphyrinogen III to coproporphyrin III.

2213200:BOX37 RS30500
gene id: 2213200:BOX37_RS30500
uniprot id: A0A1J0VZM4
names: Similarity
messages: Belongs to the Rpn/YhgA-like nuclease family.

2213200:BOX37 RS15775
gene id: 2213200:BOX37_RS15775
uniprot id: A0A1J0W277
names: Function
names: Similarity
messages: Belongs to the cyanase family.
messages: Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide.

2213200:BOX37 RS11315
gene id: 2213200:BOX37_RS11315
uniprot id: A0A1J0VQW4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

2213200:BOX37 RS21660
gene id: 2213200:BOX37_RS21660
uniprot id: A0A1J0VVT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2213200:BOX37 RS12065
gene id: 2213200:BOX37_RS12065
uniprot id: A0A1J0W226
names: Similarity
messages: Belongs to the peptidase U62 family.

2213200:BOX37 RS26310
gene id: 2213200:BOX37_RS26310
uniprot id: A0A1J0VXK3
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

2213200:BOX37 RS23410
gene id: 2213200:BOX37_RS23410
uniprot id: A0A1J0VWF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

2213200:BOX37 RS01430
gene id: 2213200:BOX37_RS01430
uniprot id: A0A1J0VLG3
names: Function
names: Similarity
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids lysine, threonine, isoleucine and methionine.

2213200:BOX37 RS13475
gene id: 2213200:BOX37_RS13475
uniprot id: A0A1J0VRT2
names: Similarity
messages: Belongs to the asparagine synthetase family.

2213200:BOX37 RS18515
gene id: 2213200:BOX37_RS18515
uniprot id: A0A1J0VU62
names: Similarity
messages: Belongs to the cytochrome P450 family.

2213200:BOX37 RS32130
gene id: 2213200:BOX37_RS32130
uniprot id: A0A1J0W0E8
names: Similarity
messages: Belongs to the F420H(2)-dependent quinone reductase family.

2213200:BOX37 RS14250
gene id: 2213200:BOX37_RS14250
uniprot id: A0A1J0VS66
names: Similarity
messages: Belongs to the FAD-binding monooxygenase family.

2213200:BOX37 RS02045
gene id: 2213200:BOX37_RS02045
uniprot id: A0A1J0VLN5
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

2213200:BOX37 RS12205
gene id: 2213200:BOX37_RS12205
uniprot id: A0A1J0VR92
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the peroxidase family. Peroxidase/catalase subfamily.
messages: Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.
messages: Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2213200:BOX37 RS22200
gene id: 2213200:BOX37_RS22200
uniprot id: A0A1J0VVQ4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

2213200:BOX37 RS26770
gene id: 2213200:BOX37_RS26770
uniprot id: A0A1J0VY00
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HsdR family.
messages: Subunit R is required for both nuclease and ATPase activities, but not for modification.
messages: The type I restriction/modification system is composed of three polypeptides R, M and S.

2213200:BOX37 RS27670
gene id: 2213200:BOX37_RS27670
uniprot id: A0A1J0VYD0
names: Subcellular Location Annotation
messages: Membrane

2213200:BOX37 RS04165
gene id: 2213200:BOX37_RS04165
uniprot id: A0A1J0W104
names: Similarity
messages: Belongs to the CsoR family.

2213200:BOX37 RS19590
gene id: 2213200:BOX37_RS19590
uniprot id: A0A1J0VUM0
names: Similarity
messages: Belongs to the peptidase A24 family.

2213200:BOX37 RS12645
gene id: 2213200:BOX37_RS12645
uniprot id: A0A1J0W240
names: Similarity
messages: Belongs to the peptidase S33 family.

2213200:BOX37 RS01910
gene id: 2213200:BOX37_RS01910
uniprot id: A0A1J0VLL8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

2213200:BOX37 RS08155
gene id: 2213200:BOX37_RS08155
uniprot id: A0A1J0VPJ4
names: Subcellular Location Annotation
messages: Cytoplasm

2213200:BOX37 RS23805
gene id: 2213200:BOX37_RS23805
uniprot id: A0A1J0W2X0
names: Similarity
messages: Belongs to the CdaR family.

2213200:BOX37 RS05400
gene id: 2213200:BOX37_RS05400
uniprot id: A0A1J0VNA3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

2213200:BOX37 RS04520
gene id: 2213200:BOX37_RS04520
uniprot id: A0A1J0VMV8
names: Similarity
messages: Belongs to the UPF0235 family.

2213200:BOX37 RS29175
gene id: 2213200:BOX37_RS29175
uniprot id: A0A1J0VYT0
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: Could possibly oxidize fatty acids using specific components.

2213200:BOX37 RS10235
gene id: 2213200:BOX37_RS10235
uniprot id: A0A1J0VQG3
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2213200:BOX37 RS04145
gene id: 2213200:BOX37_RS04145
uniprot id: A0A1J0VML7
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. Nitrilase family.

2213200:BOX37 RS00455
gene id: 2213200:BOX37_RS00455
uniprot id: A0A1J0VKY3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

2213200:BOX37 RS11220
gene id: 2213200:BOX37_RS11220
uniprot id: A0A1J0VQU9
names: Subcellular Location Annotation
messages: Membrane

2213200:BOX37 RS04110
gene id: 2213200:BOX37_RS04110
uniprot id: A0A1J0VMN8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

2213200:BOX37 RS00610
gene id: 2213200:BOX37_RS00610
uniprot id: A0A1J0VL27
names: Subcellular Location Annotation
messages: Membrane

2213200:BOX37 RS10040
gene id: 2213200:BOX37_RS10040
uniprot id: A0A1J0W1I2
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

2213200:BOX37 RS22080
gene id: 2213200:BOX37_RS22080
uniprot id: A0A1J0VVP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

2213200:BOX37 RS00790
gene id: 2213200:BOX37_RS00790
uniprot id: A0A1J0VL65
names: Similarity
messages: Belongs to the EspG family.

2213200:BOX37 RS26565
gene id: 2213200:BOX37_RS26565
uniprot id: A0A1J0W366
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

2213200:BOX37 RS04985
gene id: 2213200:BOX37_RS04985
uniprot id: A0A1J0VN01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

2213200:BOX37 RS04550
gene id: 2213200:BOX37_RS04550
uniprot id: A0A1J0VMV6
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

2213200:BOX37 RS14650
gene id: 2213200:BOX37_RS14650
uniprot id: A0A1J0VSD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

2213200:BOX37 RS30635
gene id: 2213200:BOX37_RS30635
uniprot id: A0A1J0VZP5
names: Subcellular Location Annotation
messages: Membrane

2213200:BOX37 RS04670
gene id: 2213200:BOX37_RS04670
uniprot id: A0A1J0VMV5
names: Similarity
messages: Belongs to the UPF0758 family.

2213200:BOX37 RS25025
gene id: 2213200:BOX37_RS25025
uniprot id: A0A1J0VX52
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CofD family.
messages: Catalyzes the transfer of the phosphoenolpyruvate moiety from enoylpyruvoyl-2-diphospho-5'-guanosine (EPPG) to 7,8-didemethyl-8-hydroxy-5-deazariboflavin (FO) with the formation of dehydro coenzyme F420-0 and GMP.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2213200:BOX37 RS19280
gene id: 2213200:BOX37_RS19280
uniprot id: A0A1J0W2F4
names: Subcellular Location Annotation
messages: Membrane

2213200:BOX37 RS19400
gene id: 2213200:BOX37_RS19400
uniprot id: A0A1J0W2H3
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

2213200:BOX37 RS23520
gene id: 2213200:BOX37_RS23520
uniprot id: A0A1J0VWB6
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

2213200:BOX37 RS30790
gene id: 2213200:BOX37_RS30790
uniprot id: A0A1J0VZZ4
names: Similarity
names: Subunit
messages: Belongs to the sigma-70 factor family. ECF subfamily.
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

2213200:BOX37 RS04525
gene id: 2213200:BOX37_RS04525
uniprot id: A0A1J0VMT0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Could methylate the ribose at the nucleotide 34 wobble position in tRNA.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2213200:BOX37 RS08760
gene id: 2213200:BOX37_RS08760
uniprot id: A0A1J0VPV0
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

2213200:BOX37 RS15185
gene id: 2213200:BOX37_RS15185
uniprot id: A0A1J0VSM9
names: Similarity
messages: Belongs to the cytochrome P450 family.

2213200:BOX37 RS18555
gene id: 2213200:BOX37_RS18555
uniprot id: A0A1J0VU95
names: Subcellular Location Annotation
messages: Membrane

2213200:BOX37 RS17975
gene id: 2213200:BOX37_RS17975
uniprot id: A0A1J0VU00
names: Similarity
messages: Belongs to the AB hydrolase superfamily. Lipase family.

2213200:BOX37 RS03730
gene id: 2213200:BOX37_RS03730
uniprot id: A0A1J0VMH4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

2213200:BOX37 RS30915
gene id: 2213200:BOX37_RS30915
uniprot id: A0A1J0W3W7
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

2213200:BOX37 RS27350
gene id: 2213200:BOX37_RS27350
uniprot id: A0A1J0VY25
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

2213200:BOX37 RS19360
gene id: 2213200:BOX37_RS19360
uniprot id: A0A1J0VUH6
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

2213200:BOX37 RS17240
gene id: 2213200:BOX37_RS17240
uniprot id: A0A1J0VTJ8
names: Similarity
messages: Belongs to the lysine N(6)-hydroxylase/L-ornithine N(5)-oxygenase family.

2213200:BOX37 RS05315
gene id: 2213200:BOX37_RS05315
uniprot id: A0A1J0VN56
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

2213200:BOX37 RS22220
gene id: 2213200:BOX37_RS22220
uniprot id: A0A1J0VVT8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

2213200:BOX37 RS30665
gene id: 2213200:BOX37_RS30665
uniprot id: A0A1J0VZJ4
names: Subcellular Location Annotation
messages: Membrane

2213200:BOX37 RS28950
gene id: 2213200:BOX37_RS28950
uniprot id: A0A1J0W3E0
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

2213200:BOX37 RS26560
gene id: 2213200:BOX37_RS26560
uniprot id: A0A1J0W397
names: Subcellular Location Annotation
messages: Secreted

2213200:BOX37 RS01925
gene id: 2213200:BOX37_RS01925
uniprot id: A0A1J0VLP2
names: Subcellular Location Annotation
messages: Membrane

2213200:BOX37 RS23230
gene id: 2213200:BOX37_RS23230
uniprot id: A0A1J0VWB9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2213200:BOX37 RS06540
gene id: 2213200:BOX37_RS06540
uniprot id: A0A1J0VNS3
names: Similarity
messages: Belongs to the AB hydrolase superfamily. Lipase family.

2213200:BOX37 RS05565
gene id: 2213200:BOX37_RS05565
uniprot id: A0A1J0VNA0
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

2213200:BOX37 RS19315
gene id: 2213200:BOX37_RS19315
uniprot id: A0A1J0VUG8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gluconeogenesis factor family.
messages: Cytoplasm
messages: Required for morphogenesis under gluconeogenic growth conditions.

2213200:BOX37 RS01290
gene id: 2213200:BOX37_RS01290
uniprot id: A0A1J0VLD7
names: Similarity
messages: Belongs to the CFA/CMAS family.

2213200:BOX37 RS20355
gene id: 2213200:BOX37_RS20355
uniprot id: A0A1J0W2J2
names: Similarity
messages: Belongs to the CdaR family.

2213200:BOX37 RS08755
gene id: 2213200:BOX37_RS08755
uniprot id: A0A1J0VPU9
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

2213200:BOX37 RS26260
gene id: 2213200:BOX37_RS26260
uniprot id: A0A1J0VXR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic pantothenate kinase family.
messages: Cytoplasm

2213200:BOX37 RS31350
gene id: 2213200:BOX37_RS31350
uniprot id: A0A1J0VZZ2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.

2213200:BOX37 RS29770
gene id: 2213200:BOX37_RS29770
uniprot id: A0A1J0VZA3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

2213200:BOX37 RS30325
gene id: 2213200:BOX37_RS30325
uniprot id: A0A1J0VZJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

2213200:BOX37 RS01990
gene id: 2213200:BOX37_RS01990
uniprot id: A0A1J0VLM7
names: Similarity
messages: Belongs to the Nth/MutY family.

2213200:BOX37 RS30995
gene id: 2213200:BOX37_RS30995
uniprot id: A0A1J0VZV3
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

2213200:BOX37 RS20390
gene id: 2213200:BOX37_RS20390
uniprot id: A0A1J0VV17
names: Subcellular Location Annotation
messages: Membrane

2213200:BOX37 RS16500
gene id: 2213200:BOX37_RS16500
uniprot id: A0A1J0W2A8
names: Cofactor
names: Function
messages: Binds 1 [3Fe-4S] cluster.
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

2213200:BOX37 RS30340
gene id: 2213200:BOX37_RS30340
uniprot id: A0A1J0VZS2
names: Subcellular Location Annotation
messages: Membrane

2213200:BOX37 RS27325
gene id: 2213200:BOX37_RS27325
uniprot id: A0A1J0VYD6
names: Similarity
messages: Belongs to the cytochrome P450 family.

2213200:BOX37 RS15150
gene id: 2213200:BOX37_RS15150
uniprot id: A0A1J0VSX0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2213200:BOX37 RS18660
gene id: 2213200:BOX37_RS18660
uniprot id: A0A1J0VU84
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: Could possibly oxidize fatty acids using specific components.

2213200:BOX37 RS21205
gene id: 2213200:BOX37_RS21205
uniprot id: A0A1J0VVG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

2213200:BOX37 RS27570
gene id: 2213200:BOX37_RS27570
uniprot id: A0A1J0VY24
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily.
messages: Cytoplasm
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

2213200:BOX37 RS10670
gene id: 2213200:BOX37_RS10670
uniprot id: A0A1J0VQL8
names: Similarity
messages: Belongs to the adenylyl cyclase class-3 family.

2213200:BOX37 RS31455
gene id: 2213200:BOX37_RS31455
uniprot id: A0A1J0W020
names: Caution
names: Similarity
messages: Belongs to the globin family. Two-domain flavohemoproteins subfamily.
messages: In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2213200:BOX37 RS10045
gene id: 2213200:BOX37_RS10045
uniprot id: A0A1J0VQB9
names: Similarity
messages: Belongs to the AB hydrolase superfamily. Lipase family.

2213200:BOX37 RS26130
gene id: 2213200:BOX37_RS26130
uniprot id: A0A1J0VXM5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

2213200:BOX37 RS05900
gene id: 2213200:BOX37_RS05900
uniprot id: A0A1J0VNH8
names: Similarity
messages: Belongs to the AB hydrolase superfamily. Lipase family.

2213200:BOX37 RS24990
gene id: 2213200:BOX37_RS24990
uniprot id: A0A1J0VX10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acid desaturase type 1 family. AlkB subfamily.
messages: Cell inner membrane
messages: Membrane

2213200:BOX37 RS04070
gene id: 2213200:BOX37_RS04070
uniprot id: A0A1J0VMM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S8 family.
messages: Cell membrane
messages: Membrane

2213200:BOX37 RS16615
gene id: 2213200:BOX37_RS16615
uniprot id: A0A1J0VT84
names: Similarity
messages: Belongs to the AccD/PCCB family.

2213200:BOX37 RS15210
gene id: 2213200:BOX37_RS15210
uniprot id: A0A1J0VSP4
names: Similarity
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Homohexamer. The oligomerization is ATP-dependent.

2213200:BOX37 RS10305
gene id: 2213200:BOX37_RS10305
uniprot id: A0A1J0W1I9
names: Similarity
messages: Belongs to the UPF0434 family.

2213200:BOX37 RS12280
gene id: 2213200:BOX37_RS12280
uniprot id: A0A1J0VRC5
names: Function
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

2213200:BOX37 RS06650
gene id: 2213200:BOX37_RS06650
uniprot id: A0A1J0VNU5
names: Similarity
messages: Belongs to the FPG family.

2213200:BOX37 RS16320
gene id: 2213200:BOX37_RS16320
uniprot id: A0A1J0VT55
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MshC subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent condensation of GlcN-Ins and L-cysteine to form L-Cys-GlcN-Ins.
messages: Monomer.

2213200:BOX37 RS29330
gene id: 2213200:BOX37_RS29330
uniprot id: A0A1J0W3D7
names: Subcellular Location Annotation
messages: Membrane

2213200:BOX37 RS31385
gene id: 2213200:BOX37_RS31385
uniprot id: A0A1J0W092
names: Similarity
messages: Belongs to the thiolase-like superfamily. FabH family.

2213200:BOX37 RS22085
gene id: 2213200:BOX37_RS22085
uniprot id: A0A1J0VVT0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

2213200:BOX37 RS30770
gene id: 2213200:BOX37_RS30770
uniprot id: A0A1J0W3J0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cell surface
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
messages: capsule
messages: cell wall

2213200:BOX37 RS28875
gene id: 2213200:BOX37_RS28875
uniprot id: A0A1J0VYN8
names: Similarity
messages: Belongs to the AB hydrolase superfamily. Lipase family.

2213200:BOX37 RS32205
gene id: 2213200:BOX37_RS32205
uniprot id: A0A1J0W097
names: Similarity
messages: Belongs to the TPP enzyme family.

2213200:BOX37 RS05405
gene id: 2213200:BOX37_RS05405
uniprot id: A0A1J0VN76
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

2213200:BOX37 RS27020
gene id: 2213200:BOX37_RS27020
uniprot id: A0A1J0VY29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EccB family.
messages: Membrane

2213200:BOX37 RS01135
gene id: 2213200:BOX37_RS01135
uniprot id: A0A1J0VLB8
names: Subcellular Location Annotation
messages: Membrane

2213200:BOX37 RS30100
gene id: 2213200:BOX37_RS30100
uniprot id: A0A1J0VZE7
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

2213200:BOX37 RS14440
gene id: 2213200:BOX37_RS14440
uniprot id: A0A1J0VSC5
names: Similarity
messages: Belongs to the YciI family.

2213200:BOX37 RS00910
gene id: 2213200:BOX37_RS00910
uniprot id: A0A1J0VL77
names: Subcellular Location Annotation
messages: Membrane

2213200:BOX37 RS09235
gene id: 2213200:BOX37_RS09235
uniprot id: A0A1J0VQ13
names: Similarity
messages: Belongs to the UDPGP type 2 family.

2213200:BOX37 RS29220
gene id: 2213200:BOX37_RS29220
uniprot id: A0A1J0VZ22
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

2213200:BOX37 RS11715
gene id: 2213200:BOX37_RS11715
uniprot id: A0A1J0VR45
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

2213200:BOX37 RS08555
gene id: 2213200:BOX37_RS08555
uniprot id: A0A1J0VPM9
names: Activity Regulation
names: Caution
names: Function
names: Similarity
messages: Allosterically activated by N-acetylglucosamine 6-phosphate (GlcNAc6P).
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
messages: Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2213200:BOX37 RS24605
gene id: 2213200:BOX37_RS24605
uniprot id: A0A1J0W337
names: Similarity
messages: Belongs to the DEAD box helicase family.

2213200:BOX37 RS21975
gene id: 2213200:BOX37_RS21975
uniprot id: A0A1J0VVM7
names: Similarity
messages: Belongs to the P(II) protein family.

2213200:BOX37 RS07665
gene id: 2213200:BOX37_RS07665
uniprot id: A0A1J0VP94
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

2213200:BOX37 RS24175
gene id: 2213200:BOX37_RS24175
uniprot id: A0A1J0VWL8
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

2213200:BOX37 RS15445
gene id: 2213200:BOX37_RS15445
uniprot id: A0A1J0VSQ2
names: Function
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Involved in the hydrocarbon hydroxylating system, which transfers electrons from NADH to rubredoxin reductase and then through rubredoxin to alkane 1 monooxygenase.

2213200:BOX37 RS00935
gene id: 2213200:BOX37_RS00935
uniprot id: A0A1J0VL83
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

2213200:BOX37 RS04940
gene id: 2213200:BOX37_RS04940
uniprot id: A0A1J0VN33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

2213200:BOX37 RS05390
gene id: 2213200:BOX37_RS05390
uniprot id: A0A1J0VN78
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

2213200:BOX37 RS26410
gene id: 2213200:BOX37_RS26410
uniprot id: A0A1J0VXS0
names: Similarity
messages: Belongs to the phD/YefM antitoxin family.

2213200:BOX37 RS20890
gene id: 2213200:BOX37_RS20890
uniprot id: A0A1J0VV60
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

2213200:BOX37 RS29255
gene id: 2213200:BOX37_RS29255
uniprot id: A0A1J0VZ33
names: Similarity
messages: Belongs to the DyP-type peroxidase family.

2213200:BOX37 RS16775
gene id: 2213200:BOX37_RS16775
uniprot id: A0A1J0VTM3
names: Similarity
messages: Belongs to the cytochrome P450 family.

2213200:BOX37 RS14220
gene id: 2213200:BOX37_RS14220
uniprot id: A0A1J0VS62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

2213200:BOX37 RS00845
gene id: 2213200:BOX37_RS00845
uniprot id: A0A1J0VL71
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Arabinosyl transferase responsible for the polymerization of arabinose into the arabinan of arabinogalactan.
messages: Belongs to the emb family.
messages: Cell membrane
messages: Membrane

2213200:BOX37 RS06165
gene id: 2213200:BOX37_RS06165
uniprot id: A0A1J0VNL8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

2213200:BOX37 RS19185
gene id: 2213200:BOX37_RS19185
uniprot id: A0A1J0VUF5
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

2213200:BOX37 RS18530
gene id: 2213200:BOX37_RS18530
uniprot id: A0A1J0VU65
names: Similarity
messages: Belongs to the HIBADH-related family.

2213200:BOX37 RS12335
gene id: 2213200:BOX37_RS12335
uniprot id: A0A1J0VRB6
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the RuBisCO small chain family.
messages: Heterohexadecamer of 8 large and 8 small subunits.
messages: RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site. Although the small subunit is not catalytic it is essential for maximal activity.
messages: The basic functional RuBisCO is composed of a large chain homodimer in a 'head-to-tail' conformation. In form I RuBisCO this homodimer is arranged in a barrel-like tetramer with the small subunits forming a tetrameric 'cap' on each end of the 'barrel'.

2213200:BOX37 RS02700
gene id: 2213200:BOX37_RS02700
uniprot id: A0A1J0VM13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 87 family.
messages: Membrane

2213200:BOX37 RS09535
gene id: 2213200:BOX37_RS09535
uniprot id: A0A1J0VQ56
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

2213200:BOX37 RS30480
gene id: 2213200:BOX37_RS30480
uniprot id: A0A1J0VZG1
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 independent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.

2213200:BOX37 RS08000
gene id: 2213200:BOX37_RS08000
uniprot id: A0A1J0W1I0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SURF1 family.
messages: Cell membrane

2213200:BOX37 RS07130
gene id: 2213200:BOX37_RS07130
uniprot id: A0A1J0VP23
names: Function
messages: Catalyzes the reduction of sulfite to sulfide, a step in the biosynthesis of sulfur-containing amino acids and cofactors.

2213200:BOX37 RS11550
gene id: 2213200:BOX37_RS11550
uniprot id: A0A1J0VR08
names: Similarity
names: Subunit
messages: Belongs to the AAA ATPase family.
messages: Homohexamer. Assembles into a hexameric ring structure.

2213200:BOX37 RS23165
gene id: 2213200:BOX37_RS23165
uniprot id: A0A1J0VWH6
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

2213200:BOX37 RS02175
gene id: 2213200:BOX37_RS02175
uniprot id: A0A1J0VLT0
names: Similarity
messages: Belongs to the acetaldehyde dehydrogenase family.

2213200:BOX37 RS32575
gene id: 2213200:BOX37_RS32575
uniprot id: A0A1J0W0Q6
names: Similarity
messages: Belongs to the long-chain O-acyltransferase family.

2213200:BOX37 RS27560
gene id: 2213200:BOX37_RS27560
uniprot id: A0A1J0VY86
names: Similarity
messages: Belongs to the transglycosylase family. Rpf subfamily.

2213200:BOX37 RS21935
gene id: 2213200:BOX37_RS21935
uniprot id: A0A1J0VVM0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

2213200:BOX37 RS03030
gene id: 2213200:BOX37_RS03030
uniprot id: A0A1J0VM60
names: Similarity
names: Subunit
messages: Belongs to the sigma-70 factor family. ECF subfamily.
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

2213200:BOX37 RS24455
gene id: 2213200:BOX37_RS24455
uniprot id: A0A1J0W307
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

2213200:BOX37 RS29845
gene id: 2213200:BOX37_RS29845
uniprot id: A0A1J0VZ67
names: Similarity
messages: Belongs to the UPF0234 family.

2213200:BOX37 RS01885
gene id: 2213200:BOX37_RS01885
uniprot id: A0A1J0VLM6
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

2213200:BOX37 RS14000
gene id: 2213200:BOX37_RS14000
uniprot id: A0A1J0VS37
names: Similarity
messages: Belongs to the universal stress protein A family.

2213200:BOX37 RS02795
gene id: 2213200:BOX37_RS02795
uniprot id: A0A1J0VM18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell inner membrane
messages: Membrane

2213200:BOX37 RS08095
gene id: 2213200:BOX37_RS08095
uniprot id: A0A1J0VPI1
names: Similarity
messages: Belongs to the glutamine synthetase family.

2213200:BOX37 RS06870
gene id: 2213200:BOX37_RS06870
uniprot id: A0A1J0VNY4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

2213200:BOX37 RS04840
gene id: 2213200:BOX37_RS04840
uniprot id: A0A1J0VN16
names: Similarity
messages: Belongs to the FPG family.

2213200:BOX37 RS10590
gene id: 2213200:BOX37_RS10590
uniprot id: A0A1J0VQS5
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

2213200:BOX37 RS05490
gene id: 2213200:BOX37_RS05490
uniprot id: A0A1J0VND3
names: Subcellular Location Annotation
messages: Membrane

2213200:BOX37 RS15155
gene id: 2213200:BOX37_RS15155
uniprot id: A0A1J0VSL3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

2213200:BOX37 RS07935
gene id: 2213200:BOX37_RS07935
uniprot id: A0A1J0VPF7
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: Acyl carrier protein involved in meromycolate extension.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

2213200:BOX37 RS31235
gene id: 2213200:BOX37_RS31235
uniprot id: A0A1J0W034
names: Function
names: Similarity
names: Subunit
messages: Belongs to the trans-sulfuration enzymes family. MetZ subfamily.
messages: Catalyzes the formation of L-homocysteine from O-succinyl-L-homoserine (OSHS) and hydrogen sulfide.
messages: Homotetramer.

2213200:BOX37 RS08030
gene id: 2213200:BOX37_RS08030
uniprot id: A0A1J0VPK9
names: Similarity
messages: Belongs to the peptidase S1 family.

2213200:BOX37 RS03680
gene id: 2213200:BOX37_RS03680
uniprot id: A0A1J0VMG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Membrane

2213200:BOX37 RS08870
gene id: 2213200:BOX37_RS08870
uniprot id: A0A1J0VPT5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Membrane

2213200:BOX37 RS03285
gene id: 2213200:BOX37_RS03285
uniprot id: A0A1J0VMA0
names: Similarity
messages: Belongs to the AccD/PCCB family.

2213200:BOX37 RS11880
gene id: 2213200:BOX37_RS11880
uniprot id: A0A1J0VR44
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

2213200:BOX37 RS01855
gene id: 2213200:BOX37_RS01855
uniprot id: A0A1J0VLL5
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

2213200:BOX37 RS20190
gene id: 2213200:BOX37_RS20190
uniprot id: A0A1J0VUV3
names: Similarity
messages: Belongs to the nitrile hydratase subunit alpha family.

2213200:BOX37 RS19975
gene id: 2213200:BOX37_RS19975
uniprot id: A0A1J0VUT1
names: Similarity
messages: Belongs to the YciI family.

2213200:BOX37 RS15290
gene id: 2213200:BOX37_RS15290
uniprot id: A0A1J0VSN9
names: Subcellular Location Annotation
messages: Membrane

2213200:BOX37 RS30080
gene id: 2213200:BOX37_RS30080
uniprot id: A0A1J0VZN4
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

2213200:BOX37 RS30465
gene id: 2213200:BOX37_RS30465
uniprot id: A0A1J0VZN9
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

2213200:BOX37 RS02035
gene id: 2213200:BOX37_RS02035
uniprot id: A0A1J0VLN7
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.

2213200:BOX37 RS14885
gene id: 2213200:BOX37_RS14885
uniprot id: A0A1J0VSH0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

2213200:BOX37 RS02675
gene id: 2213200:BOX37_RS02675
uniprot id: A0A1J0VLZ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

2213200:BOX37 RS01600
gene id: 2213200:BOX37_RS01600
uniprot id: A0A1J0VLJ2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell inner membrane
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

2213200:BOX37 RS18590
gene id: 2213200:BOX37_RS18590
uniprot id: A0A1J0VU55
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

2213200:BOX37 RS03875
gene id: 2213200:BOX37_RS03875
uniprot id: A0A1J0VMK0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

2213200:BOX37 RS21455
gene id: 2213200:BOX37_RS21455
uniprot id: A0A1J0VVE7
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

2213200:BOX37 RS08245
gene id: 2213200:BOX37_RS08245
uniprot id: A0A1J0VPK5
names: Subcellular Location Annotation
messages: Membrane

2213200:BOX37 RS00030
gene id: 2213200:BOX37_RS00030
uniprot id: A0A1J0VKR3
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

2213200:BOX37 RS06455
gene id: 2213200:BOX37_RS06455
uniprot id: A0A1J0VNP3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

2213200:BOX37 RS30025
gene id: 2213200:BOX37_RS30025
uniprot id: A0A1J0VZE8
names: Subcellular Location Annotation
messages: Membrane

2213200:BOX37 RS01780
gene id: 2213200:BOX37_RS01780
uniprot id: A0A1J0VLL7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

2213200:BOX37 RS21055
gene id: 2213200:BOX37_RS21055
uniprot id: A0A1J0VVB4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

2213200:BOX37 RS24525
gene id: 2213200:BOX37_RS24525
uniprot id: A0A1J0VWU1
names: Function
messages: Catalyzes the reduction of sulfite to sulfide, a step in the biosynthesis of sulfur-containing amino acids and cofactors.

2213200:BOX37 RS19285
gene id: 2213200:BOX37_RS19285
uniprot id: A0A1J0VUH2
names: Similarity
messages: Belongs to the MmpS family.

2213200:BOX37 RS29390
gene id: 2213200:BOX37_RS29390
uniprot id: A0A1J0VZ42
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

2213200:BOX37 RS03930
gene id: 2213200:BOX37_RS03930
uniprot id: A0A1J0W150
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

2213200:BOX37 RS21860
gene id: 2213200:BOX37_RS21860
uniprot id: A0A1J0VVN3
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

2213200:BOX37 RS18175
gene id: 2213200:BOX37_RS18175
uniprot id: A0A1J0VU33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

2213200:BOX37 RS25785
gene id: 2213200:BOX37_RS25785
uniprot id: A0A1J0VXH8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgE subfamily.
messages: Homodimer.
messages: Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1->4)-glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB.

2213200:BOX37 RS23515
gene id: 2213200:BOX37_RS23515
uniprot id: A0A1J0VWG9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

2213200:BOX37 RS25985
gene id: 2213200:BOX37_RS25985
uniprot id: A0A1J0VXG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 87 family.
messages: Membrane

2213200:BOX37 RS02735
gene id: 2213200:BOX37_RS02735
uniprot id: A0A1J0W1A6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase Z family.
messages: Binds 2 Zn(2+) ions.
messages: Homodimer.
messages: Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.

2213200:BOX37 RS23160
gene id: 2213200:BOX37_RS23160
uniprot id: A0A1J0VW88
names: Similarity
messages: Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.

2213200:BOX37 RS15015
gene id: 2213200:BOX37_RS15015
uniprot id: A0A1J0VSL1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

2213200:BOX37 RS10490
gene id: 2213200:BOX37_RS10490
uniprot id: A0A1J0VQR3
names: Function
names: Similarity
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids lysine, threonine, isoleucine and methionine.

2213200:BOX37 RS29065
gene id: 2213200:BOX37_RS29065
uniprot id: A0A1J0VYZ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

2213200:BOX37 RS30535
gene id: 2213200:BOX37_RS30535
uniprot id: A0A1J0VZG6
names: Similarity
messages: Belongs to the allantoicase family.

2213200:BOX37 RS06470
gene id: 2213200:BOX37_RS06470
uniprot id: A0A1J0VNR9
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

2213200:BOX37 RS14780
gene id: 2213200:BOX37_RS14780
uniprot id: A0A1J0VSF2
names: Similarity
messages: Belongs to the cytochrome P450 family.

2213200:BOX37 RS24715
gene id: 2213200:BOX37_RS24715
uniprot id: A0A1J0VWT3
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family. MbtB subfamily.

2213200:BOX37 RS19645
gene id: 2213200:BOX37_RS19645
uniprot id: A0A1J0VUQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase MltG family.
messages: Cell membrane
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

2213200:BOX37 RS32920
gene id: 2213200:BOX37_RS32920
uniprot id: A0A1J0W0W2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2213200:BOX37 RS27980
gene id: 2213200:BOX37_RS27980
uniprot id: A0A1J0W3D4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
messages: Membrane

2213200:BOX37 RS19575
gene id: 2213200:BOX37_RS19575
uniprot id: A0A1J0VUQ9
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

2213200:BOX37 RS09975
gene id: 2213200:BOX37_RS09975
uniprot id: A0A1J0W1H2
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.

2213200:BOX37 RS20610
gene id: 2213200:BOX37_RS20610
uniprot id: A0A1J0W2Y5
names: Similarity
names: Subunit
messages: Belongs to the glutaminase family.
messages: Homotetramer.

2213200:BOX37 RS24120
gene id: 2213200:BOX37_RS24120
uniprot id: A0A1J0VWL2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in cellular division.

2213200:BOX37 RS04660
gene id: 2213200:BOX37_RS04660
uniprot id: A0A1J0VMY1
names: Similarity
messages: Belongs to the biopterin-dependent aromatic amino acid hydroxylase family.

2213200:BOX37 RS06900
gene id: 2213200:BOX37_RS06900
uniprot id: A0A1J0VP09
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein L14 (rplN).

2213200:BOX37 RS14350
gene id: 2213200:BOX37_RS14350
uniprot id: A0A1J0VS80
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

2213200:BOX37 RS27925
gene id: 2213200:BOX37_RS27925
uniprot id: A0A1J0VYH3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

2213200:BOX37 RS00205
gene id: 2213200:BOX37_RS00205
uniprot id: A0A1J0VKW4
names: Subcellular Location Annotation
messages: Membrane

2213200:BOX37 RS11620
gene id: 2213200:BOX37_RS11620
uniprot id: A0A1J0W1V0
names: Similarity
messages: Belongs to the ArsC family.

2213200:BOX37 RS02455
gene id: 2213200:BOX37_RS02455
uniprot id: A0A1J0VLW6
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

2213200:BOX37 RS12820
gene id: 2213200:BOX37_RS12820
uniprot id: A0A1J0VRJ5
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

2213200:BOX37 RS03915
gene id: 2213200:BOX37_RS03915
uniprot id: A0A1J0VMJ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

2213200:BOX37 RS09190
gene id: 2213200:BOX37_RS09190
uniprot id: A0A1J0VQ15
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

2213200:BOX37 RS13775
gene id: 2213200:BOX37_RS13775
uniprot id: A0A1J0VS03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

2213200:BOX37 RS10150
gene id: 2213200:BOX37_RS10150
uniprot id: A0A1J0VQL3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

2213200:BOX37 RS30095
gene id: 2213200:BOX37_RS30095
uniprot id: A0A1J0VZI4
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

2213200:BOX37 RS00460
gene id: 2213200:BOX37_RS00460
uniprot id: A0A1J0VKX5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

2213200:BOX37 RS10945
gene id: 2213200:BOX37_RS10945
uniprot id: A0A1J0VQR9
names: Function
names: Similarity
messages: ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.
messages: Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.

2213200:BOX37 RS01325
gene id: 2213200:BOX37_RS01325
uniprot id: A0A1J0VLD8
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.