219594:STUM
gene id: 219594:STUM
uniprot id: A0A6J3CKD1
names: Subcellular Location Annotation
messages: Membrane

219594:TMEM263
gene id: 219594:TMEM263
uniprot id: A0A6J3EPA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM263 family.
messages: Membrane

219594:APAF1
gene id: 219594:APAF1
uniprot id: A0A6J3E0P4
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Monomer. Oligomerizes upon binding of cytochrome c and dATP.
messages: Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.

219594:NOL6
gene id: 219594:NOL6
uniprot id: A0A6J3EIP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NRAP family.
messages: nucleolus

219594:SLC28A2
gene id: 219594:SLC28A2
uniprot id: A0A6J3DHC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.
messages: Membrane

219594:SETD2
gene id: 219594:SETD2
uniprot id: A0A6J3CFQ0
names: Subcellular Location Annotation
messages: Nucleus

219594:RAMP2
gene id: 219594:RAMP2
uniprot id: A0A6J3E9G0
names: Similarity
messages: Belongs to the RAMP family.

219594:SLC39A9
gene id: 219594:SLC39A9
uniprot id: A0A6J3D4Q8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZIP transporter (TC 2.A.5) family.
messages: May act as a zinc-influx transporter.
messages: Membrane

219594:JAKMIP2
gene id: 219594:JAKMIP2
uniprot id: A0A6J3DML3
names: Similarity
messages: Belongs to the JAKMIP family.

219594:TMEM251
gene id: 219594:TMEM251
uniprot id: A0A6J3D1U5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM251 family.
messages: Membrane

219594:RPL14
gene id: 219594:RPL14
uniprot id: A0A6J3CKD9
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL14 family.

219594:LOC116498314
gene id: 219594:LOC116498314
uniprot id: A0A6J3E484
names: Similarity
names: Subunit
messages: Belongs to the avian keratin family.
messages: The avian keratins (F-ker, S-ker, C-ker and B-ker) are a complex mixture of very similar polypeptides.

219594:PRICKLE2
gene id: 219594:PRICKLE2
uniprot id: A0A6J3DJW1
names: Similarity
messages: Belongs to the prickle / espinas / testin family.

219594:LOC116496251
gene id: 219594:LOC116496251
uniprot id: A0A6J3E0L9
names: Similarity
messages: Belongs to the gonadal family.

219594:BEST4
gene id: 219594:BEST4
uniprot id: A0A6J3DDD0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bestrophin family.
messages: Cell membrane
messages: Forms chloride channels.
messages: Membrane

219594:GHSR
gene id: 219594:GHSR
uniprot id: A0A6J3DIR2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for ghrelin, coupled to G-alpha-11 proteins. Stimulates growth hormone secretion. Binds also other growth hormone releasing peptides (GHRP) (e.g. Met-enkephalin and GHRP-6) as well as non-peptide, low molecular weight secretagogues (e.g. L-692,429, MK-0677, adenosine).

219594:DKK1
gene id: 219594:DKK1
uniprot id: A0A6J3D809
names: Similarity
messages: Belongs to the dickkopf family.

219594:LOC116500149
gene id: 219594:LOC116500149
uniprot id: A0A6J3ECK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:LOC116498307
gene id: 219594:LOC116498307
uniprot id: A0A6J3E8K2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:ITGA2B
gene id: 219594:ITGA2B
uniprot id: A0A6J3E5N7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

219594:CPB2
gene id: 219594:CPB2
uniprot id: A0A6J3EHJ3
names: Similarity
messages: Belongs to the peptidase M14 family.

219594:HOXD13
gene id: 219594:HOXD13
uniprot id: A0A6J3DAX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus

219594:LOC116502358
gene id: 219594:LOC116502358
uniprot id: A0A6J3EQP4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

219594:PSIP1
gene id: 219594:PSIP1
uniprot id: A0A6J3ECY5
uniprot id: A0A6J3EJS3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HDGF family.
messages: Nucleus

219594:C7
gene id: 219594:C7
uniprot id: A0A6J3EFX9
uniprot id: A0A6J3EL59
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complement C6/C7/C8/C9 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

219594:LOC116486841
gene id: 219594:LOC116486841
uniprot id: A0A6J3CME5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the DNA photolyase class-1 family.
messages: Binds 1 5,10-methenyltetrahydrofolate (MTHF) per subunit.
messages: Binds 1 FAD per subunit.
messages: May have a photoreceptor function.

219594:RXRG
gene id: 219594:RXRG
uniprot id: A0A6J3DEV1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nuclear hormone receptor family. NR2 subfamily.
messages: Composed of three domains: a modulating N-terminal domain, a DNA-binding domain and a C-terminal ligand-binding domain.
messages: Homodimer. Heterodimer; with a rar molecule.
messages: Nucleus
messages: Receptor for retinoic acid that acts as a transcription factor. Forms homo- or heterodimers with retinoic acid receptors (rars) and binds to target response elements in response to their ligands, all-trans or 9-cis retinoic acid, to regulate gene expression in various biological processes.

219594:PLPP3
gene id: 219594:PLPP3
uniprot id: A0A6J3DE49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Membrane

219594:LOC116502285
gene id: 219594:LOC116502285
uniprot id: A0A6J3EQ56
names: Similarity
messages: Belongs to the interleukin-1 receptor family.

219594:GNG2
gene id: 219594:GNG2
uniprot id: A0A6J3D6P3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G protein gamma family.
messages: Cell membrane
messages: G proteins are composed of 3 units; alpha, beta and gamma.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

219594:GPM6B
gene id: 219594:GPM6B
uniprot id: A0A6J3D998
uniprot id: A0A6J3D9B6
uniprot id: A0A6J3D9C4
uniprot id: A0A6J3D9H3
uniprot id: A0A6J3DC74
uniprot id: A0A6J3DD09
uniprot id: A0A6J3DD20
uniprot id: A0A6J3DF11
uniprot id: A0A6J3DF45
uniprot id: A0A6J3DF57
uniprot id: A0A6J3DF68
uniprot id: A0A6J3DFC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the myelin proteolipid protein family.
messages: Membrane

219594:PRKCQ
gene id: 219594:PRKCQ
uniprot id: A0A6J3DUR0
uniprot id: A0A6J3DVJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
messages: Cytoplasm

219594:LMOD3
gene id: 219594:LMOD3
uniprot id: A0A6J3DL94
names: Subcellular Location Annotation
messages: cytoskeleton
messages: sarcomere

219594:LOC116489198
gene id: 219594:LOC116489198
uniprot id: A0A6J3CYF0
names: Similarity
messages: Belongs to the vasopressin/oxytocin family.

219594:NAGK
gene id: 219594:NAGK
uniprot id: A0A6J3CWZ9
names: Similarity
messages: Belongs to the eukaryotic-type N-acetylglucosamine kinase family.

219594:TMPRSS13
gene id: 219594:TMPRSS13
uniprot id: A0A6J3E888
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:SSR1
gene id: 219594:SSR1
uniprot id: A0A6J3CGG8
uniprot id: A0A6J3CK20
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP-alpha family.
messages: Endoplasmic reticulum membrane
messages: Heterotetramer of TRAP-alpha, TRAP-beta, TRAP-delta and TRAP-gamma.
messages: Membrane
messages: Shows a remarkable charge distribution with the N-terminus being highly negatively charged, and the cytoplasmic C-terminus positively charged.
messages: TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins. May be involved in the recycling of the translocation apparatus after completion of the translocation process or may function as a membrane-bound chaperone facilitating folding of translocated proteins.

219594:FAM199X
gene id: 219594:FAM199X
uniprot id: A0A6J3DT22
names: Similarity
messages: Belongs to the FAM199 family.

219594:FRMPD2
gene id: 219594:FRMPD2
uniprot id: A0A6J3DA02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class subfamily.
messages: cytoskeleton

219594:GPNMB
gene id: 219594:GPNMB
uniprot id: A0A6J3CIB5
names: Similarity
messages: Belongs to the PMEL/NMB family.

219594:ACTR10
gene id: 219594:ACTR10
uniprot id: A0A6J3D1R1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the actin family.
messages: cytoskeleton

219594:ACTR3
gene id: 219594:ACTR3
uniprot id: A0A6J3D734
names: Similarity
messages: Belongs to the actin family. ARP3 subfamily.

219594:LOC116499597
gene id: 219594:LOC116499597
uniprot id: A0A6J3EDX1
names: Similarity
names: Subunit
messages: Belongs to the avian keratin family.
messages: The avian keratins (F-ker, S-ker, C-ker and B-ker) are a complex mixture of very similar polypeptides.

219594:EDNRA
gene id: 219594:EDNRA
uniprot id: A0A6J3CUW0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Interacts with HDAC7 and KAT5.
messages: Membrane
messages: Receptor for endothelin-1. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of binding affinities for ET-A is: ET1 > ET2 >> ET3.

219594:UBE4B
gene id: 219594:UBE4B
uniprot id: A0A6J3E5X1
uniprot id: A0A6J3E706
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ubiquitin conjugation factor E4 family.
messages: Cytoplasm

219594:CORO2B
gene id: 219594:CORO2B
uniprot id: A0A6J3DHT6
uniprot id: A0A6J3DNA8
names: Similarity
messages: Belongs to the WD repeat coronin family.

219594:ERGIC2
gene id: 219594:ERGIC2
uniprot id: A0A6J3DAS4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERGIC family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Golgi apparatus membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays a role in transport between endoplasmic reticulum and Golgi.

219594:BAZ2A
gene id: 219594:BAZ2A
uniprot id: A0A6J3EBM7
names: Similarity
messages: Belongs to the WAL family.

219594:PDIA3
gene id: 219594:PDIA3
uniprot id: A0A6J3DHV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein disulfide isomerase family.
messages: Endoplasmic reticulum lumen

219594:SLC26A6
gene id: 219594:SLC26A6
uniprot id: A0A6J3DHX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

219594:DYNC2H1
gene id: 219594:DYNC2H1
uniprot id: A0A6J3DGS6
names: Similarity
messages: Belongs to the dynein heavy chain family.

219594:MRPS15
gene id: 219594:MRPS15
uniprot id: A0A6J3E4P8
names: Similarity
messages: Belongs to the universal ribosomal protein uS15 family.

219594:DPYSL2
gene id: 219594:DPYSL2
uniprot id: A0A6J3E9L7
uniprot id: A0A6J3EEW9
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.

219594:XPO7
gene id: 219594:XPO7
uniprot id: A0A6J3EDK2
uniprot id: A0A6J3EF96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exportin family.
messages: Cytoplasm
messages: Nucleus

219594:SHANK2
gene id: 219594:SHANK2
uniprot id: A0A6J3CZX8
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Postsynaptic density

219594:ND3
gene id: 219594:ND3
uniprot id: A0A068L9B6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 3 family.
messages: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity of complex I.
messages: Mitochondrion membrane

219594:RNF2
gene id: 219594:RNF2
uniprot id: A0A6J3DGF1
names: Subcellular Location Annotation
messages: Chromosome
messages: Cytoplasm

219594:AP4B1
gene id: 219594:AP4B1
uniprot id: A0A6J3E6F7
names: Similarity
messages: Belongs to the adaptor complexes large subunit family.

219594:KCNJ8
gene id: 219594:KCNJ8
uniprot id: A0A6J3DS93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.
messages: Membrane

219594:SUSD2
gene id: 219594:SUSD2
uniprot id: A0A6J3DXA5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:ASTL
gene id: 219594:ASTL
uniprot id: A0A6J3EEZ4
names: Caution
names: Cofactor
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:EIF3M
gene id: 219594:EIF3M
uniprot id: A0A6J3D663
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CSN7/EIF3M family. CSN7 subfamily.
messages: Belongs to the eIF-3 subunit M family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
messages: Cytoplasm

219594:STXBP5L
gene id: 219594:STXBP5L
uniprot id: A0A6J3DGP2
uniprot id: A0A6J3DIA3
uniprot id: A0A6J3DIB1
uniprot id: A0A6J3DIX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat L(2)GL family.
messages: Cell membrane
messages: Cytoplasm
messages: Membrane

219594:TRPC7
gene id: 219594:TRPC7
uniprot id: A0A6J3DUM3
names: Subcellular Location Annotation
messages: Membrane

219594:TOMM22
gene id: 219594:TOMM22
uniprot id: A0A6J3DIC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tom22 family.
messages: Mitochondrion outer membrane

219594:LOC116492938
gene id: 219594:LOC116492938
uniprot id: A0A6J3DKI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone H1/H5 family.
messages: Nucleus

219594:TMEM33
gene id: 219594:TMEM33
uniprot id: A0A6J3CVS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PER33/POM33 family.
messages: Membrane

219594:LOC116485351
gene id: 219594:LOC116485351
uniprot id: A0A6J3CGF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-7/IL-9 family.
messages: Secreted

219594:XYLT1
gene id: 219594:XYLT1
uniprot id: A0A6J3DPD8
uniprot id: A0A6J3DVH5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycosyltransferase 14 family. XylT subfamily.
messages: Golgi apparatus membrane
messages: Membrane
messages: Monomer.

219594:LOC116496101
gene id: 219594:LOC116496101
uniprot id: A0A6J3DY87
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway.
messages: Belongs to the VPS29 family.
messages: Endosome membrane

219594:EIF3A
gene id: 219594:EIF3A
uniprot id: A0A6J3D837
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit A family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M.
messages: Cytoplasm
messages: RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.

219594:YBEY
gene id: 219594:YBEY
uniprot id: A0A6J3D8I8
names: Similarity
messages: Belongs to the endoribonuclease YbeY family.

219594:PLPP4
gene id: 219594:PLPP4
uniprot id: A0A6J3D877
uniprot id: A0A6J3DBR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Membrane

219594:GOT2
gene id: 219594:GOT2
uniprot id: A0A6J3DQJ4
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.
messages: In eukaryotes there are cytoplasmic, mitochondrial and chloroplastic isozymes.

219594:SCD5
gene id: 219594:SCD5
uniprot id: A0A6J3CVB8
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acid desaturase type 1 family.
messages: Membrane
messages: The histidine box domains are involved in binding the catalytic metal ions.

219594:APOLD1
gene id: 219594:APOLD1
uniprot id: A0A6J3E539
names: Similarity
messages: Belongs to the apolipoprotein L family.

219594:LOC116497193
gene id: 219594:LOC116497193
uniprot id: A0A6J3DZA3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal Rpo11/eukaryotic RPB11/RPC19 RNA polymerase subunit family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB11 is part of the core element with the central large cleft.
messages: Nucleus

219594:POFUT2
gene id: 219594:POFUT2
uniprot id: A0A6J3D2N0
names: Similarity
messages: Belongs to the glycosyltransferase 68 family.

219594:UNC5A
gene id: 219594:UNC5A
uniprot id: A0A6J3DT40
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the unc-5 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for netrin required for axon guidance. Mediates axon repulsion of neuronal growth cones in the developing nervous system upon ligand binding.

219594:ND1
gene id: 219594:ND1
uniprot id: A0A068LAT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 1 family.
messages: Membrane
messages: Mitochondrion inner membrane

219594:CRYBA4
gene id: 219594:CRYBA4
uniprot id: A0A6J3E179
names: Function
names: Similarity
names: Subunit
messages: Belongs to the beta/gamma-crystallin family.
messages: Crystallins are the dominant structural components of the vertebrate eye lens.
messages: Homo/heterodimer, or complexes of higher-order. The structure of beta-crystallin oligomers seems to be stabilized through interactions between the N-terminal arms.

219594:FOXC2
gene id: 219594:FOXC2
uniprot id: A0A6J3DQE3
names: Subcellular Location Annotation
messages: Nucleus

219594:MMS22L
gene id: 219594:MMS22L
uniprot id: A0A6J3CX28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MMS22 family. MMS22L subfamily.
messages: Chromosome
messages: Nucleus

219594:CD8B
gene id: 219594:CD8B
uniprot id: A0A6J3CZ33
names: Subcellular Location Annotation
messages: Membrane

219594:NPVF
gene id: 219594:NPVF
uniprot id: A0A6J3CC19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FARP (FMRFamide related peptide) family.
messages: Secreted

219594:PSME3
gene id: 219594:PSME3
uniprot id: A0A6J3E4H8
uniprot id: A0A6J3E8U7
names: Similarity
messages: Belongs to the PA28 family.

219594:NTF3
gene id: 219594:NTF3
uniprot id: A0A6J3ED81
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NGF-beta family.
messages: Secreted
messages: Seems to promote the survival of visceral and proprioceptive sensory neurons.

219594:MINDY4
gene id: 219594:MINDY4
uniprot id: A0A6J3CHQ1
uniprot id: A0A6J3CIQ7
names: Function
names: Similarity
messages: Belongs to the MINDY deubiquitinase family. FAM188 subfamily.
messages: Hydrolase that can remove 'Lys-48'-linked conjugated ubiquitin from proteins.

219594:LOC116500324
gene id: 219594:LOC116500324
uniprot id: A0A6J3EGU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:RAB9A
gene id: 219594:RAB9A
uniprot id: A0A6J3DD73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: phagosome membrane

219594:LIN7C
gene id: 219594:LIN7C
uniprot id: A0A6J3D129
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lin-7 family.
messages: Cell junction
messages: Cell membrane
messages: Membrane
messages: Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells.

219594:DDI2
gene id: 219594:DDI2
uniprot id: A0A6J3E860
names: Similarity
messages: Belongs to the DDI1 family.

219594:NUDT18
gene id: 219594:NUDT18
uniprot id: A0A6J3E9Z1
names: Similarity
messages: Belongs to the Nudix hydrolase family.

219594:TLR7
gene id: 219594:TLR7
uniprot id: A0A6J3DR37
uniprot id: A0A6J3DX83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Toll-like receptor family.
messages: Endoplasmic reticulum membrane
messages: Lysosome
messages: Membrane
messages: phagosome

219594:LOC116501357
gene id: 219594:LOC116501357
uniprot id: A0A6J3EHR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:ELL3
gene id: 219594:ELL3
uniprot id: A0A6J3DHH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELL/occludin family.
messages: Nucleus

219594:CORO1C
gene id: 219594:CORO1C
uniprot id: A0A6J3DWP0
names: Similarity
messages: Belongs to the WD repeat coronin family.

219594:LAMC3
gene id: 219594:LAMC3
uniprot id: A0A6J3E4H7
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: basement membrane

219594:LOC116492687
gene id: 219594:LOC116492687
uniprot id: A0A6J3DD96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the interleukin-1 receptor family.
messages: axon
messages: dendrite

219594:SPO11
gene id: 219594:SPO11
uniprot id: A0A6J3DYR1
names: Similarity
messages: Belongs to the TOP6A family.

219594:GLP1R
gene id: 219594:GLP1R
uniprot id: A0A6J3CPK7
uniprot id: A0A6J3CRM1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

219594:PAQR3
gene id: 219594:PAQR3
uniprot id: A0A6J3CYD5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

219594:GBX1
gene id: 219594:GBX1
uniprot id: A0A6J3CLB8
names: Subcellular Location Annotation
messages: Nucleus

219594:TMEM132C
gene id: 219594:TMEM132C
uniprot id: A0A6J3DVW5
uniprot id: A0A6J3DYW7
uniprot id: A0A6J3DZY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM132 family.
messages: Membrane

219594:MED12L
gene id: 219594:MED12L
uniprot id: A0A6J3DBR5
uniprot id: A0A6J3DEC8
uniprot id: A0A6J3DED3
uniprot id: A0A6J3DFI7
uniprot id: A0A6J3DFJ4
uniprot id: A0A6J3DH95
uniprot id: A0A6J3DHT4
uniprot id: A0A6J3DHT9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mediator complex subunit 12 family.
messages: Nucleus

219594:CTNNA2
gene id: 219594:CTNNA2
uniprot id: A0A6J3CTL3
uniprot id: A0A6J3CZQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vinculin/alpha-catenin family.
messages: Cell membrane
messages: Membrane
messages: Nucleus
messages: adherens junction
messages: axon
messages: cytoskeleton

219594:LOC116496414
gene id: 219594:LOC116496414
uniprot id: A0A6J3E1M0
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

219594:RAB3GAP1
gene id: 219594:RAB3GAP1
uniprot id: A0A6J3D575
uniprot id: A0A6J3DB45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Rab3-GAP catalytic subunit family.
messages: Cytoplasm

219594:PAM
gene id: 219594:PAM
uniprot id: A0A6J3EC77
uniprot id: A0A6J3EDJ9
uniprot id: A0A6J3EIX8
names: Similarity
names: Subcellular Location Annotation
messages: In the C-terminal section; belongs to the peptidyl-alpha-hydroxyglycine alpha-amidating lyase family.
messages: In the N-terminal section; belongs to the copper type II ascorbate-dependent monooxygenase family.
messages: Membrane
messages: secretory vesicle membrane

219594:PIAS3
gene id: 219594:PIAS3
uniprot id: A0A6J3EA44
names: Similarity
messages: Belongs to the PIAS family.

219594:TMED6
gene id: 219594:TMED6
uniprot id: A0A6J3DIG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Endoplasmic reticulum membrane
messages: Membrane

219594:LOC116501471
gene id: 219594:LOC116501471
uniprot id: A0A6J3EGT9
uniprot id: A0A6J3EGU4
uniprot id: A0A6J3EGU8
uniprot id: A0A6J3EIC4
uniprot id: A0A6J3EID0
uniprot id: A0A6J3EM38
uniprot id: A0A6J3EM50
uniprot id: A0A6J3EM53
uniprot id: A0A6J3ENH7
uniprot id: A0A6J3ENI2
names: Similarity
messages: Belongs to the dymeclin family.

219594:CSMD3
gene id: 219594:CSMD3
uniprot id: A0A6J3CHE8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:KDM3A
gene id: 219594:KDM3A
uniprot id: A0A6J3D1R8
names: Subcellular Location Annotation
messages: Nucleus

219594:TEKT1
gene id: 219594:TEKT1
uniprot id: A0A6J3E1H3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tektin family.
messages: flagellum

219594:CHRDL1
gene id: 219594:CHRDL1
uniprot id: A0A6J3DNE1
names: Subcellular Location Annotation
messages: Secreted

219594:DDRGK1
gene id: 219594:DDRGK1
uniprot id: A0A6J3CU41
names: Similarity
messages: Belongs to the DDRGK1 family.

219594:PIK3C3
gene id: 219594:PIK3C3
uniprot id: A0A6J3ED77
uniprot id: A0A6J3EI20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.
messages: Midbody

219594:NAA25
gene id: 219594:NAA25
uniprot id: A0A6J3DYF9
uniprot id: A0A6J3DZJ3
names: Similarity
messages: Belongs to the MDM20/NAA25 family.

219594:SLC7A3
gene id: 219594:SLC7A3
uniprot id: A0A6J3DKE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Cationic amino acid transporter (CAT) (TC 2.A.3.3) family.
messages: Cell membrane
messages: Membrane

219594:UROD
gene id: 219594:UROD
uniprot id: A0A6J3D8X6
names: Similarity
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Homodimer.

219594:MRPS10
gene id: 219594:MRPS10
uniprot id: A0A6J3CTU4
uniprot id: A0A6J3CUY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Mitochondrion

219594:TAS1R3
gene id: 219594:TAS1R3
uniprot id: A0A6J3E233
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

219594:LOC116493544
gene id: 219594:LOC116493544
uniprot id: A0A6J3DNJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:KCNE3
gene id: 219594:KCNE3
uniprot id: A0A6J3EKK7
names: Similarity
messages: Belongs to the potassium channel KCNE family.

219594:ZCCHC8
gene id: 219594:ZCCHC8
uniprot id: A0A6J3DUP2
uniprot id: A0A6J3DYT0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZCCHC8 family.
messages: nucleoplasm

219594:VEGFA
gene id: 219594:VEGFA
uniprot id: A0A6J3CRF5
uniprot id: A0A6J3CTR4
uniprot id: A0A6J3CU68
uniprot id: A0A6J3CWG4
names: Similarity
messages: Belongs to the PDGF/VEGF growth factor family.

219594:GPX3
gene id: 219594:GPX3
uniprot id: A0A6J3DPW9
names: Similarity
messages: Belongs to the glutathione peroxidase family.

219594:LOC116490550
gene id: 219594:LOC116490550
uniprot id: A0A6J3D320
uniprot id: A0A6J3D8V9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:ATG4C
gene id: 219594:ATG4C
uniprot id: A0A6J3DG28
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C54 family.
messages: Cysteine protease that plays a key role in autophagy by mediating both proteolytic activation and delipidation of ATG8 family proteins.
messages: Cytoplasm

219594:CNOT2
gene id: 219594:CNOT2
uniprot id: A0A6J3DJS9
names: Similarity
messages: Belongs to the CNOT2/3/5 family.

219594:PPIH
gene id: 219594:PPIH
uniprot id: A0A6J3E7J0
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

219594:POLRMT
gene id: 219594:POLRMT
uniprot id: A0A6J3E7B9
uniprot id: A0A6J3ECE7
names: Function
names: Similarity
messages: Belongs to the phage and mitochondrial RNA polymerase family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.

219594:KCNQ1
gene id: 219594:KCNQ1
uniprot id: A0A6J3D078
names: Similarity
names: Subcellular Location Annotation
messages: Basolateral cell membrane
messages: Belongs to the potassium channel family. KQT (TC 1.A.1.15) subfamily. Kv7.1/KCNQ1 sub-subfamily.
messages: Cell membrane
messages: Cytoplasmic vesicle membrane
messages: Endoplasmic reticulum
messages: Lateral cell membrane
messages: Membrane
messages: Membrane raft

219594:C15H16orf71
gene id: 219594:C15H16orf71
uniprot id: A0A6J3DSL8
names: Function
messages: In cyliated cells, dynein axonemal particle-specific protein required for deployment of ODA to the axoneme. Interacts with outer dynein arm (ODA) subunits.

219594:PAPSS1
gene id: 219594:PAPSS1
uniprot id: A0A6J3CSA8
names: Similarity
messages: In the C-terminal section; belongs to the sulfate adenylyltransferase family.
messages: In the N-terminal section; belongs to the APS kinase family.

219594:SLC13A2
gene id: 219594:SLC13A2
uniprot id: A0A6J3E4I7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. NADC subfamily.
messages: Membrane

219594:LOC116500238
gene id: 219594:LOC116500238
uniprot id: A0A6J3ECU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. BTN/MOG family.
messages: Membrane

219594:SF3B4
gene id: 219594:SF3B4
uniprot id: A0A6J3EF60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SF3B4 family.
messages: Nucleus

219594:RPL38
gene id: 219594:RPL38
uniprot id: A0A6J3E067
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL38 family.

219594:THYN1
gene id: 219594:THYN1
uniprot id: A0A6J3E274
names: Function
messages: Specifically binds 5-hydroxymethylcytosine (5hmC), suggesting that it acts as a specific reader of 5hmC.

219594:CACNA1E
gene id: 219594:CACNA1E
uniprot id: A0A6J3DA59
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family.
messages: Membrane
messages: Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1E gives rise to R-type calcium currents.

219594:ABAT
gene id: 219594:ABAT
uniprot id: A0A6J3DRU4
names: Similarity
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer; disulfide-linked.

219594:LOC116490628
gene id: 219594:LOC116490628
uniprot id: A0A6J3D617
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

219594:ZNF532
gene id: 219594:ZNF532
uniprot id: A0A6J3EKF9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the krueppel C2H2-type zinc-finger protein family.
messages: May be involved in transcriptional regulation.
messages: Nucleus

219594:CDK10
gene id: 219594:CDK10
uniprot id: A0A6J3DLI5
names: Similarity
messages: Belongs to the protein kinase superfamily.

219594:RB1
gene id: 219594:RB1
uniprot id: A0A6J3DX77
uniprot id: A0A6J3DZH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the retinoblastoma protein (RB) family.
messages: Nucleus

219594:NCOA1
gene id: 219594:NCOA1
uniprot id: A0A6J3CQL4
uniprot id: A0A6J3CSV4
uniprot id: A0A6J3CVL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SRC/p160 nuclear receptor coactivator family.
messages: Nucleus

219594:PIEZO1
gene id: 219594:PIEZO1
uniprot id: A0A6J3DPG2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIEZO (TC 1.A.75) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

219594:TAF5L
gene id: 219594:TAF5L
uniprot id: A0A6J3CTS6
names: Similarity
messages: Belongs to the WD repeat TAF5 family.

219594:ITGA10
gene id: 219594:ITGA10
uniprot id: A0A6J3E929
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

219594:NDFIP1
gene id: 219594:NDFIP1
uniprot id: A0A6J3DS46
names: Subcellular Location Annotation
messages: Membrane

219594:CFAP299
gene id: 219594:CFAP299
uniprot id: A0A6J3CY20
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: May be involved in spermatogenesis.
messages: Nucleus

219594:PKDREJ
gene id: 219594:PKDREJ
uniprot id: A0A6J3CTQ2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polycystin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

219594:NAB2
gene id: 219594:NAB2
uniprot id: A0A6J3EAN3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NAB family.
messages: Homomultimers may associate with EGR1 bound to DNA.
messages: Nucleus

219594:HGH1
gene id: 219594:HGH1
uniprot id: A0A6J3CJT7
names: Similarity
messages: Belongs to the HGH1 family.

219594:XKR5
gene id: 219594:XKR5
uniprot id: A0A6J3CQK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XK family.
messages: Membrane

219594:LOC116491937
gene id: 219594:LOC116491937
uniprot id: A0A6J3DFI5
names: Similarity
messages: Belongs to the janus family.

219594:FGF17
gene id: 219594:FGF17
uniprot id: A0A6J3EF16
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

219594:LOC116490067
gene id: 219594:LOC116490067
uniprot id: A0A6J3D303
names: Domain
names: Subcellular Location Annotation
messages: The N-terminal C2 domain associates with lipid membranes upon calcium binding.
messages: cytosol

219594:MYF5
gene id: 219594:MYF5
uniprot id: A0A6J3ER18
names: Subcellular Location Annotation
names: Subunit
messages: Efficient DNA binding requires dimerization with another bHLH protein.
messages: Nucleus

219594:LOC116496671
gene id: 219594:LOC116496671
uniprot id: A0A6J3E1N4
names: Subcellular Location Annotation
messages: Membrane

219594:CFAP126
gene id: 219594:CFAP126
uniprot id: A0A6J3EE88
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the Flattop family.

219594:LOC116492939
gene id: 219594:LOC116492939
uniprot id: A0A6J3DID6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

219594:KIF18B
gene id: 219594:KIF18B
uniprot id: A0A6J3E5N3
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

219594:GSR
gene id: 219594:GSR
uniprot id: A0A6J3CZ61
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Cytoplasm
messages: Maintains high levels of reduced glutathione in the cytosol.

219594:LOC116501377
gene id: 219594:LOC116501377
uniprot id: A0A6J3EGC6
uniprot id: A0A6J3ELL1
uniprot id: A0A6J3ELP3
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

219594:SDF4
gene id: 219594:SDF4
uniprot id: A0A6J3E797
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CREC family.
messages: Golgi apparatus lumen

219594:PES1
gene id: 219594:PES1
uniprot id: A0A6J3DZ48
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pescadillo family.
messages: Component of the PeBoW complex, composed of BOP1, PES1 and WDR12. Within the PeBoW complex BOP1 interacts directly with PES1 and WDR12. The PeBoW complex also associates with the 66S pre-ribosome.
messages: Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.
messages: nucleolus
messages: nucleoplasm

219594:LOC116494255
gene id: 219594:LOC116494255
uniprot id: A0A6J3DMS1
uniprot id: A0A6J3DMS5
uniprot id: A0A6J3DPK0
uniprot id: A0A6J3DPK4
uniprot id: A0A6J3DQS1
uniprot id: A0A6J3DRJ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PICALM/SNAP91 family.
messages: Belongs to the prefoldin subunit alpha family.
messages: Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins.
messages: Heterohexamer of two PFD-alpha type and four PFD-beta type subunits.

219594:SLC26A8
gene id: 219594:SLC26A8
uniprot id: A0A6J3EAM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

219594:NCOA7
gene id: 219594:NCOA7
uniprot id: A0A6J3CKX7
uniprot id: A0A6J3CRW1
uniprot id: A0A6J3CRW5
names: Similarity
messages: Belongs to the OXR1 family.

219594:GNRH1
gene id: 219594:GNRH1
uniprot id: A0A6J3EFG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GnRH family.
messages: Secreted

219594:KCNJ16
gene id: 219594:KCNJ16
uniprot id: A0A6J3DWE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.
messages: Membrane

219594:CLPS
gene id: 219594:CLPS
uniprot id: A0A6J3EAG9
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Colipase is a cofactor of pancreatic lipase. It allows the lipase to anchor itself to the lipid-water interface. Without colipase the enzyme is washed off by bile salts, which have an inhibitory effect on the lipase.
messages: Enterostatin has a biological activity as a satiety signal.
messages: Forms a 1:1 stoichiometric complex with pancreatic lipase.
messages: Secreted

219594:CFL2
gene id: 219594:CFL2
uniprot id: A0A6J3D0V0
uniprot id: A0A6J3D0X6
names: Similarity
messages: Belongs to the actin-binding proteins ADF family.

219594:LSM3
gene id: 219594:LSM3
uniprot id: A0A6J3DJL9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the snRNP Sm proteins family.
messages: Binds specifically to the 3'-terminal U-tract of U6 snRNA.
messages: LSm subunits form a heteromer with a doughnut shape.
messages: Nucleus

219594:YPEL4
gene id: 219594:YPEL4
uniprot id: A0A6J3CZG3
names: Similarity
messages: Belongs to the yippee family.

219594:DAPK2
gene id: 219594:DAPK2
uniprot id: A0A6J3DHS7
uniprot id: A0A6J3DLV6
names: Similarity
messages: Belongs to the protein kinase superfamily.

219594:ARHGEF12
gene id: 219594:ARHGEF12
uniprot id: A0A6J3E3H0
uniprot id: A0A6J3E726
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Membrane

219594:HOXB1
gene id: 219594:HOXB1
uniprot id: A0A6J3EA16
names: Subcellular Location Annotation
messages: Nucleus

219594:NEK7
gene id: 219594:NEK7
uniprot id: A0A6J3DEB8
names: Similarity
messages: Belongs to the protein kinase superfamily.

219594:MINPP1
gene id: 219594:MINPP1
uniprot id: A0A6J3D976
names: Similarity
messages: Belongs to the histidine acid phosphatase family. MINPP1 subfamily.

219594:HGS
gene id: 219594:HGS
uniprot id: A0A6J3DWK3
uniprot id: A0A6J3E1I4
names: Subcellular Location Annotation
messages: Early endosome membrane

219594:HCRT
gene id: 219594:HCRT
uniprot id: A0A6J3E9U5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the orexin family.
messages: Cytoplasmic vesicle
messages: Endoplasmic reticulum
messages: Synapse
messages: Vesicle

219594:LDLRAD4
gene id: 219594:LDLRAD4
uniprot id: A0A6J3CHA3
uniprot id: A0A6J3CK77
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMEPA1 family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

219594:FBXO34
gene id: 219594:FBXO34
uniprot id: A0A6J3D1U4
names: Function
messages: Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex.

219594:SPP2
gene id: 219594:SPP2
uniprot id: A0A6J3D5A1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPP2 family.
messages: Could coordinate an aspect of bone turnover.
messages: Secreted

219594:LOC116494816
gene id: 219594:LOC116494816
uniprot id: A0A6J3DS80
names: Similarity
messages: Belongs to the LECT2/MIM-1 family.

219594:SEPTIN7
gene id: 219594:SEPTIN7
uniprot id: A0A6J3CJY3
uniprot id: A0A6J3CPN5
uniprot id: A0A6J3CQX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
messages: Cleavage furrow
messages: Midbody
messages: cilium axoneme
messages: kinetochore
messages: spindle

219594:ZBED4
gene id: 219594:ZBED4
uniprot id: A0A6J3EJU3
names: Subcellular Location Annotation
messages: Nucleus

219594:HECTD1
gene id: 219594:HECTD1
uniprot id: A0A6J3D1J0
uniprot id: A0A6J3D1J5
uniprot id: A0A6J3D3X5
uniprot id: A0A6J3D496
uniprot id: A0A6J3D4A1
uniprot id: A0A6J3D6H6
uniprot id: A0A6J3D7C6
uniprot id: A0A6J3D7C9
names: Function
names: Similarity
messages: Belongs to the UPL family. K-HECT subfamily.
messages: E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.

219594:MYCBP
gene id: 219594:MYCBP
uniprot id: A0A6J3E7M8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AMY1 family.
messages: Nucleus

219594:NAP1L1
gene id: 219594:NAP1L1
uniprot id: A0A6J3CQG1
uniprot id: A0A6J3CT77
uniprot id: A0A6J3CVE5
names: Similarity
messages: Belongs to the nucleosome assembly protein (NAP) family.

219594:MSH6
gene id: 219594:MSH6
uniprot id: A0A6J3CS53
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: Component of the post-replicative DNA mismatch repair system (MMR).

219594:RPS15
gene id: 219594:RPS15
uniprot id: A0A6J3E6U6
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.

219594:CENPT
gene id: 219594:CENPT
uniprot id: A0A6J3DIZ1
uniprot id: A0A6J3DN44
uniprot id: A0A6J3DPE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CENP-T/CNN1 family.
messages: Nucleus
messages: kinetochore

219594:IRF2BPL
gene id: 219594:IRF2BPL
uniprot id: A0A6J3D1X3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IRF2BP family.
messages: Nucleus

219594:DERL1
gene id: 219594:DERL1
uniprot id: A0A6J3CKE8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the derlin family.
messages: Endoplasmic reticulum membrane
messages: Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome.
messages: Membrane

219594:CHMP4B
gene id: 219594:CHMP4B
uniprot id: A0A6J3DWD4
names: Similarity
messages: Belongs to the SNF7 family.

219594:NDUFB8
gene id: 219594:NDUFB8
uniprot id: A0A6J3DAC0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFB8 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

219594:SHOC2
gene id: 219594:SHOC2
uniprot id: A0A6J3D9D0
names: Function
names: Similarity
messages: Belongs to the SHOC2 family.
messages: Regulatory subunit of protein phosphatase 1 (PP1c) that acts as a M-Ras/MRAS effector and participates in MAPK pathway activation. Upon M-Ras/MRAS activation, targets PP1c to specifically dephosphorylate the 'Ser-259' inhibitory site of RAF1 kinase and stimulate RAF1 activity at specialized signaling complexes.

219594:CRHR1
gene id: 219594:CRHR1
uniprot id: A0A6J3E4Y7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family.
messages: Cell membrane
messages: Membrane

219594:UFD1
gene id: 219594:UFD1
uniprot id: A0A6J3DWJ1
uniprot id: A0A6J3E0M3
names: Similarity
messages: Belongs to the UFD1 family.

219594:DYNC1I2
gene id: 219594:DYNC1I2
uniprot id: A0A6J3D388
uniprot id: A0A6J3D5S6
uniprot id: A0A6J3D931
names: Similarity
messages: Belongs to the dynein intermediate chain family.

219594:AGTPBP1
gene id: 219594:AGTPBP1
uniprot id: A0A6J3EIU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M14 family.
messages: cytosol

219594:RABEP1
gene id: 219594:RABEP1
uniprot id: A0A6J3E3V7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the rabaptin family.
messages: Cytoplasm
messages: Early endosome
messages: Endosome

219594:MTG2
gene id: 219594:MTG2
uniprot id: A0A6J3DX22
names: Similarity
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.

219594:LIPT1
gene id: 219594:LIPT1
uniprot id: A0A6J3DNT7
names: Similarity
messages: Belongs to the LplA family.

219594:AIFM1
gene id: 219594:AIFM1
uniprot id: A0A6J3DR36
uniprot id: A0A6J3DRX8
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase family.

219594:MTMR12
gene id: 219594:MTMR12
uniprot id: A0A6J3EEM9
uniprot id: A0A6J3EJP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.
messages: Sarcoplasmic reticulum
messages: sarcomere

219594:GJC2
gene id: 219594:GJC2
uniprot id: A0A6J3CH60
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

219594:SLC35D2
gene id: 219594:SLC35D2
uniprot id: A0A6J3EJQ8
names: Subcellular Location Annotation
messages: Membrane

219594:HTATSF1
gene id: 219594:HTATSF1
uniprot id: A0A6J3DQ46
names: Similarity
messages: Belongs to the HTATSF1 family.

219594:ADRB1
gene id: 219594:ADRB1
uniprot id: A0A6J3DDI6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:SOD2
gene id: 219594:SOD2
uniprot id: A0A6J3CQ46
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.
messages: Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.
messages: Homotetramer.
messages: Mitochondrion matrix

219594:ANKRD13B
gene id: 219594:ANKRD13B
uniprot id: A0A6J3E101
uniprot id: A0A6J3E3P6
names: Function
names: Subcellular Location Annotation
messages: Endosome
messages: Late endosome
messages: Membrane
messages: Ubiquitin-binding protein that specifically recognizes and binds 'Lys-63'-linked ubiquitin. Does not bind 'Lys-48'-linked ubiquitin. Positively regulates the internalization of ligand-activated EGFR by binding to the Ub moiety of ubiquitinated EGFR at the cell membrane.

219594:INPP4B
gene id: 219594:INPP4B
uniprot id: A0A6J3CTM7
uniprot id: A0A6J3CVY1
uniprot id: A0A6J3CWC5
uniprot id: A0A6J3CYQ0
uniprot id: A0A6J3CZR6
names: Similarity
messages: Belongs to the inositol 3,4-bisphosphate 4-phosphatase family.

219594:ADAM33
gene id: 219594:ADAM33
uniprot id: A0A6J3D0W0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:TNNT2
gene id: 219594:TNNT2
uniprot id: A0A6J3E627
uniprot id: A0A6J3EAK4
uniprot id: A0A6J3EB63
names: Function
names: Similarity
messages: Belongs to the troponin T family.
messages: Troponin T is the tropomyosin-binding subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity.

219594:RIMBP2
gene id: 219594:RIMBP2
uniprot id: A0A6J3DT50
uniprot id: A0A6J3DT57
uniprot id: A0A6J3DT62
uniprot id: A0A6J3DV44
uniprot id: A0A6J3DXB6
uniprot id: A0A6J3DXC2
uniprot id: A0A6J3DY44
uniprot id: A0A6J3DY49
uniprot id: A0A6J3DY54
uniprot id: A0A6J3DZ80
uniprot id: A0A6J3DZ85
names: Similarity
messages: Belongs to the RIMBP family.

219594:LOC116494906
gene id: 219594:LOC116494906
uniprot id: A0A6J3DSL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: centrosome

219594:DKK3
gene id: 219594:DKK3
uniprot id: A0A6J3D4H2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dickkopf family.
messages: Secreted

219594:CREM
gene id: 219594:CREM
uniprot id: A0A6J3CGF7
uniprot id: A0A6J3CI08
uniprot id: A0A6J3CJ29
uniprot id: A0A6J3CL02
uniprot id: A0A6J3CMN2
names: Subcellular Location Annotation
messages: Nucleus

219594:DNTTIP1
gene id: 219594:DNTTIP1
uniprot id: A0A6J3DTY7
uniprot id: A0A6J3DW57
names: Subcellular Location Annotation
messages: Nucleus

219594:LOC116495850
gene id: 219594:LOC116495850
uniprot id: A0A6J3DUS5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IRF family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

219594:ATP7A
gene id: 219594:ATP7A
uniprot id: A0A6J3DKI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Membrane
messages: trans-Golgi network membrane

219594:LOC116501310
gene id: 219594:LOC116501310
uniprot id: A0A6J3ELE0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:SEPSECS
gene id: 219594:SEPSECS
uniprot id: A0A6J3CWH1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SepSecS family.
messages: Converts O-phosphoseryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.
messages: Cytoplasm
messages: Homotetramer formed by a catalytic dimer and a non-catalytic dimer serving as a binding platform that orients tRNASec for catalysis. Each tetramer binds the CCA ends of two tRNAs which point to the active sites of the catalytic dimer.

219594:TLR3
gene id: 219594:TLR3
uniprot id: A0A6J3D1D4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Toll-like receptor family.
messages: Membrane

219594:SPSB4
gene id: 219594:SPSB4
uniprot id: A0A6J3DIY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPSB family.
messages: Cytoplasm

219594:VPS37A
gene id: 219594:VPS37A
uniprot id: A0A6J3CWS9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS37 family.
messages: Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. May be involved in cell growth and differentiation.
messages: Endosome membrane
messages: Late endosome membrane

219594:MVK
gene id: 219594:MVK
uniprot id: A0A6J3E0U4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Mevalonate kinase subfamily.
messages: Catalyzes the phosphorylation of mevalonate to mevalonate 5-phosphate, a key step in isoprenoid and cholesterol biosynthesis.
messages: Cytoplasm

219594:EGFL7
gene id: 219594:EGFL7
uniprot id: A0A6J3DYQ6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:PLPP5
gene id: 219594:PLPP5
uniprot id: A0A6J3E8A5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Membrane

219594:AP1M1
gene id: 219594:AP1M1
uniprot id: A0A6J3EBP7
names: Similarity
messages: Belongs to the adaptor complexes medium subunit family.

219594:KCNK10
gene id: 219594:KCNK10
uniprot id: A0A6J3D4P2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

219594:SLC10A2
gene id: 219594:SLC10A2
uniprot id: A0A6J3E8X5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bile acid:sodium symporter (BASS) (TC 2.A.28) family.
messages: Membrane
messages: Monomer and homodimer.

219594:LOC116502363
gene id: 219594:LOC116502363
uniprot id: A0A6J3EK30
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

219594:LOC116489511
gene id: 219594:LOC116489511
uniprot id: A0A6J3D035
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:LOC116491457
gene id: 219594:LOC116491457
uniprot id: A0A6J3DA50
names: Similarity
messages: Belongs to the cystatin family.

219594:SUDS3
gene id: 219594:SUDS3
uniprot id: A0A6J3DZ12
names: Subcellular Location Annotation
messages: Nucleus

219594:RBP1
gene id: 219594:RBP1
uniprot id: A0A6J3DIS6
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

219594:F5
gene id: 219594:F5
uniprot id: A0A6J3DIR4
names: Similarity
messages: Belongs to the multicopper oxidase family.

219594:OCLN
gene id: 219594:OCLN
uniprot id: A0A6J3ECN3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELL/occludin family.
messages: Cell membrane
messages: May play a role in the formation and regulation of the tight junction (TJ) paracellular permeability barrier.
messages: Membrane
messages: tight junction

219594:PPM1K
gene id: 219594:PPM1K
uniprot id: A0A6J3CWE6
names: Similarity
messages: Belongs to the PP2C family.

219594:SIGIRR
gene id: 219594:SIGIRR
uniprot id: A0A6J3D0B2
names: Similarity
messages: Belongs to the interleukin-1 receptor family.

219594:AGPAT5
gene id: 219594:AGPAT5
uniprot id: A0A6J3CLX6
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

219594:TTC27
gene id: 219594:TTC27
uniprot id: A0A6J3CQ89
names: Similarity
messages: Belongs to the TTC27 family.

219594:GRIK2
gene id: 219594:GRIK2
uniprot id: A0A6J3CPW4
uniprot id: A0A6J3CS61
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

219594:CIT
gene id: 219594:CIT
uniprot id: A0A6J3DV47
uniprot id: A0A6J3DV52
uniprot id: A0A6J3DWZ2
uniprot id: A0A6J3DZA2
uniprot id: A0A6J3E010
uniprot id: A0A6J3E019
uniprot id: A0A6J3E138
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.
messages: Cytoplasm
messages: Plays a role in cytokinesis. Displays serine/threonine protein kinase activity.

219594:LOC116493348
gene id: 219594:LOC116493348
uniprot id: A0A6J3DGE8
names: Subcellular Location Annotation
messages: cytoskeleton

219594:SLC8A1
gene id: 219594:SLC8A1
uniprot id: A0A6J3CRP0
uniprot id: A0A6J3CU01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. SLC8 subfamily.
messages: Cell membrane
messages: Membrane

219594:NMT2
gene id: 219594:NMT2
uniprot id: A0A6J3CJ65
names: Function
names: Similarity
messages: Adds a myristoyl group to the N-terminal glycine residue of certain cellular proteins.
messages: Belongs to the NMT family.

219594:SEPTIN4
gene id: 219594:SEPTIN4
uniprot id: A0A6J3E1L2
uniprot id: A0A6J3E694
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.

219594:ME1
gene id: 219594:ME1
uniprot id: A0A6J3CP18
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

219594:TDRD9
gene id: 219594:TDRD9
uniprot id: A0A6J3D6Q6
names: Similarity
messages: Belongs to the DEAD box helicase family. DEAH subfamily.

219594:LOC116499704
gene id: 219594:LOC116499704
uniprot id: A0A6J3EGG5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the selenium-binding protein family.
messages: Catalyzes the oxidation of methanethiol, an organosulfur compound known to be produced in substantial amounts by gut bacteria. Selenium-binding protein which may be involved in the sensing of reactive xenobiotics in the cytoplasm. May be involved in intra-Golgi protein transport.
messages: Membrane
messages: Nucleus
messages: cytosol

219594:AQP11
gene id: 219594:AQP11
uniprot id: A0A6J3EID6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family. AQP11/AQP12 subfamily.
messages: Membrane

219594:BAK1
gene id: 219594:BAK1
uniprot id: A0A6J3ED09
names: Similarity
messages: Belongs to the Bcl-2 family.

219594:STT3A
gene id: 219594:STT3A
uniprot id: A0A6J3E8X2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STT3 family.
messages: Membrane

219594:ERN2
gene id: 219594:ERN2
uniprot id: A0A6J3DVF5
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

219594:SLC46A1
gene id: 219594:SLC46A1
uniprot id: A0A6J3E6F5
names: Subcellular Location Annotation
messages: Membrane

219594:LOC116491416
gene id: 219594:LOC116491416
uniprot id: A0A6J3DAF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

219594:CRKL
gene id: 219594:CRKL
uniprot id: A0A6J3DVN0
names: Similarity
messages: Belongs to the CRK family.

219594:LOC116491819
gene id: 219594:LOC116491819
uniprot id: A0A6J3D9B1
names: Similarity
messages: Belongs to the aldo/keto reductase family.

219594:DENND6A
gene id: 219594:DENND6A
uniprot id: A0A6J3DLA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DENND6 family.
messages: Endosome
messages: Recycling endosome

219594:MANEAL
gene id: 219594:MANEAL
uniprot id: A0A6J3E7U5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 99 family.
messages: Golgi apparatus membrane
messages: Membrane

219594:BBOF1
gene id: 219594:BBOF1
uniprot id: A0A6J3CXT5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Basal body protein required in multiciliate cells to align and maintain cilia orientation in response to flow. May act by mediating a maturation step that stabilizes and aligns cilia orientation. Not required to respond to planar cell polarity (PCP) or flow-based orientation cues.
messages: Belongs to the BBOF1 family.
messages: cilium basal body

219594:NUP155
gene id: 219594:NUP155
uniprot id: A0A6J3EFZ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the non-repetitive/WGA-negative nucleoporin family.
messages: nuclear pore complex

219594:LOC116490327
gene id: 219594:LOC116490327
uniprot id: A0A6J3D6W5
uniprot id: A0A6J3D7Q9
names: Similarity
messages: Belongs to the MS4A family.

219594:SUOX
gene id: 219594:SUOX
uniprot id: A0A6J3EBL9
names: Function
names: Subunit
messages: Catalyzes the oxidation of sulfite to sulfate, the terminal reaction in the oxidative degradation of sulfur-containing amino acids.
messages: Homodimer.

219594:SGO1
gene id: 219594:SGO1
uniprot id: A0A6J3CPF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the shugoshin family.
messages: centromere

219594:PRKAR2B
gene id: 219594:PRKAR2B
uniprot id: A0A6J3DUE6
uniprot id: A0A6J3DW91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cAMP-dependent kinase regulatory chain family.
messages: Cell membrane
messages: Membrane

219594:SERF2
gene id: 219594:SERF2
uniprot id: A0A6J3DNE4
names: Similarity
messages: Belongs to the SERF family.

219594:LOC116497038
gene id: 219594:LOC116497038
uniprot id: A0A6J3DYH1
names: Similarity
messages: Belongs to the GDA1/CD39 NTPase family.

219594:CCDC126
gene id: 219594:CCDC126
uniprot id: A0A6J3CI46
names: Subcellular Location Annotation
messages: Secreted

219594:CACNA1C
gene id: 219594:CACNA1C
uniprot id: A0A6J3D2N7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. CACNA1C subfamily.
messages: Cell membrane
messages: Membrane
messages: Perikaryon
messages: Postsynaptic density membrane
messages: T-tubule
messages: Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death.
messages: dendrite
messages: sarcolemma

219594:CLIP1
gene id: 219594:CLIP1
uniprot id: A0A6J3DTP0
uniprot id: A0A6J3DTP5
uniprot id: A0A6J3DVL4
uniprot id: A0A6J3DVL9
uniprot id: A0A6J3DXV7
uniprot id: A0A6J3DXW2
uniprot id: A0A6J3DYM1
uniprot id: A0A6J3DYM6
uniprot id: A0A6J3DZP9
uniprot id: A0A6J3DZQ4
names: Subcellular Location Annotation
messages: cytoskeleton

219594:MARVELD3
gene id: 219594:MARVELD3
uniprot id: A0A6J3DQ77
names: Subcellular Location Annotation
messages: Membrane

219594:TUBGCP2
gene id: 219594:TUBGCP2
uniprot id: A0A6J3D9I0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TUBGCP family.
messages: Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome.
messages: centrosome

219594:STRN3
gene id: 219594:STRN3
uniprot id: A0A6J3D1D7
uniprot id: A0A6J3D774
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat striatin family.
messages: Membrane

219594:LOC116498861
gene id: 219594:LOC116498861
uniprot id: A0A6J3E6C3
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family. Chitinase class II subfamily.

219594:KCNJ13
gene id: 219594:KCNJ13
uniprot id: A0A6J3DHI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.
messages: Membrane

219594:LRP4
gene id: 219594:LRP4
uniprot id: A0A6J3CXU8
names: Caution
names: Similarity
messages: Belongs to the LDLR family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:RBL1
gene id: 219594:RBL1
uniprot id: A0A6J3DSC1
uniprot id: A0A6J3DUF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the retinoblastoma protein (RB) family.
messages: Nucleus

219594:OPLAH
gene id: 219594:OPLAH
uniprot id: A0A6J3CM50
names: Similarity
messages: Belongs to the oxoprolinase family.

219594:GSTO1
gene id: 219594:GSTO1
uniprot id: A0A6J3D6W8
names: Function
names: Similarity
messages: Belongs to the GST superfamily. Omega family.
messages: Exhibits glutathione-dependent thiol transferase activity. Has high dehydroascorbate reductase activity and may contribute to the recycling of ascorbic acid. Participates in the biotransformation of inorganic arsenic and reduces monomethylarsonic acid (MMA).

219594:MYF6
gene id: 219594:MYF6
uniprot id: A0A6J3EIE7
names: Subcellular Location Annotation
messages: Nucleus

219594:TCTE3
gene id: 219594:TCTE3
uniprot id: A0A6J3CRJ7
names: Similarity
messages: Belongs to the dynein light chain Tctex-type family.

219594:CHL1
gene id: 219594:CHL1
uniprot id: A0A6J3DFU7
uniprot id: A0A6J3DFV2
uniprot id: A0A6J3DII7
uniprot id: A0A6J3DJT7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. L1/neurofascin/NgCAM family.
messages: Membrane

219594:PCBD2
gene id: 219594:PCBD2
uniprot id: A0A6J3DSZ8
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

219594:TBX1
gene id: 219594:TBX1
uniprot id: A0A6J3DUQ8
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

219594:CSGALNACT1
gene id: 219594:CSGALNACT1
uniprot id: A0A6J3D2H1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chondroitin N-acetylgalactosaminyltransferase family.
messages: Golgi stack membrane
messages: Membrane

219594:TGFB2
gene id: 219594:TGFB2
uniprot id: A0A6J3CTW1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TGF-beta family.
messages: Homodimer; disulfide-linked.
messages: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-2 (TGF-beta-2) chains, which constitute the regulatory and active subunit of TGF-beta-2, respectively.
messages: extracellular matrix

219594:BATF
gene id: 219594:BATF
uniprot id: A0A6J3D1G2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family.
messages: Cytoplasm

219594:TOP2B
gene id: 219594:TOP2B
uniprot id: A0A6J3CI82
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type II topoisomerase family.
messages: Homodimer.
messages: Key decatenating enzyme that alters DNA topology by binding to two double-stranded DNA molecules, generating a double-stranded break in one of the strands, passing the intact strand through the broken strand, and religating the broken strand.
messages: nucleolus
messages: nucleoplasm

219594:FAM161B
gene id: 219594:FAM161B
uniprot id: A0A6J3D092
names: Similarity
messages: Belongs to the FAM161 family.

219594:LOC116499748
gene id: 219594:LOC116499748
uniprot id: A0A6J3EEK3
names: Similarity
names: Subunit
messages: Belongs to the avian keratin family.
messages: The avian keratins (F-ker, S-ker, C-ker and B-ker) are a complex mixture of very similar polypeptides.

219594:RPGRIP1L
gene id: 219594:RPGRIP1L
uniprot id: A0A6J3DJ46
uniprot id: A0A6J3DJ51
uniprot id: A0A6J3DLM7
uniprot id: A0A6J3DNA5
uniprot id: A0A6J3DPJ3
uniprot id: A0A6J3DQ95
names: Similarity
messages: Belongs to the RPGRIP1 family.

219594:LOC116495777
gene id: 219594:LOC116495777
uniprot id: A0A6J3DSH2
names: Similarity
messages: Belongs to the glycosyl hydrolase 47 family.

219594:CARMIL1
gene id: 219594:CARMIL1
uniprot id: A0A6J3CIM5
uniprot id: A0A6J3CK22
uniprot id: A0A6J3CK27
uniprot id: A0A6J3CLA8
uniprot id: A0A6J3CN81
uniprot id: A0A6J3CN88
uniprot id: A0A6J3CPM7
uniprot id: A0A6J3CPN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CARMIL family.
messages: Cytoplasm

219594:ARF4
gene id: 219594:ARF4
uniprot id: A0A6J3DIX7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: GTP-binding protein involved in protein trafficking; modulates vesicle budding and uncoating within the Golgi apparatus.
messages: Golgi apparatus

219594:SMAD4
gene id: 219594:SMAD4
uniprot id: A0A6J3ECB0
uniprot id: A0A6J3EH45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dwarfin/SMAD family.
messages: Cytoplasm
messages: Nucleus

219594:EML5
gene id: 219594:EML5
uniprot id: A0A6J3D053
uniprot id: A0A6J3D2R4
uniprot id: A0A6J3D606
names: Function
names: Similarity
messages: Belongs to the WD repeat EMAP family.
messages: May modify the assembly dynamics of microtubules, such that microtubules are slightly longer, but more dynamic.

219594:ALX1
gene id: 219594:ALX1
uniprot id: A0A6J3EJ60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paired homeobox family.
messages: Nucleus

219594:SERPIND1
gene id: 219594:SERPIND1
uniprot id: A0A6J3E068
names: Similarity
messages: Belongs to the serpin family.

219594:TELO2
gene id: 219594:TELO2
uniprot id: A0A6J3DSN7
names: Similarity
messages: Belongs to the TEL2 family.

219594:NAB1
gene id: 219594:NAB1
uniprot id: A0A6J3D3K0
uniprot id: A0A6J3D653
uniprot id: A0A6J3D6N0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NAB family.
messages: Homomultimers may associate with EGR1 bound to DNA.
messages: Nucleus

219594:NOX3
gene id: 219594:NOX3
uniprot id: A0A6J3CTG1
names: Subcellular Location Annotation
messages: Membrane

219594:DNAH9
gene id: 219594:DNAH9
uniprot id: A0A6J3E146
names: Similarity
messages: Belongs to the dynein heavy chain family.

219594:SEC23B
gene id: 219594:SEC23B
uniprot id: A0A6J3CNR6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEC23/SEC24 family. SEC23 subfamily.
messages: COPII-coated vesicle membrane
messages: Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: cytosol

219594:LOC116486466
gene id: 219594:LOC116486466
uniprot id: A0A6J3CJL3
names: Similarity
messages: Belongs to the biopterin-dependent aromatic amino acid hydroxylase family.

219594:HSPA5
gene id: 219594:HSPA5
uniprot id: A0A6J3E3N3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heat shock protein 70 family.
messages: Endoplasmic reticulum lumen

219594:PLEKHA8
gene id: 219594:PLEKHA8
uniprot id: A0A6J3CFN1
names: Subcellular Location Annotation
messages: Membrane
messages: trans-Golgi network membrane

219594:ADNP
gene id: 219594:ADNP
uniprot id: A0A6J3DWU6
uniprot id: A0A6J3DXV5
names: Subcellular Location Annotation
messages: Nucleus

219594:SLC35E4
gene id: 219594:SLC35E4
uniprot id: A0A6J3DYB2
names: Subcellular Location Annotation
messages: Membrane

219594:LOC116492642
gene id: 219594:LOC116492642
uniprot id: A0A6J3DGZ5
names: Subcellular Location Annotation
messages: Membrane

219594:SLC16A1
gene id: 219594:SLC16A1
uniprot id: A0A6J3ECU0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.
messages: Cell membrane
messages: Membrane
messages: Proton-coupled monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and isoleucine, and the ketone bodies acetoacetate, beta-hydroxybutyrate and acetate. Depending on the tissue and on cicumstances, mediates the import or export of lactic acid and ketone bodies. Required for normal nutrient assimilation, increase of white adipose tissue and body weight gain when on a high-fat diet. Plays a role in cellular responses to a high-fat diet by modulating the cellular levels of lactate and pyruvate, small molecules that contribute to the regulation of central metabolic pathways and insulin secretion, with concomitant effects on plasma insulin levels and blood glucose homeostasis.

219594:LOC116497724
gene id: 219594:LOC116497724
uniprot id: A0A6J3E803
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

219594:MC4R
gene id: 219594:MC4R
uniprot id: A0A6J3CJS5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor specific to the heptapeptide core common to adrenocorticotropic hormone and alpha-, beta-, and gamma-MSH. Plays a central role in energy homeostasis and somatic growth. This receptor is mediated by G proteins that stimulate adenylate cyclase (cAMP).

219594:LDLRAD3
gene id: 219594:LDLRAD3
uniprot id: A0A6J3D0G3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:EEF1A2
gene id: 219594:EEF1A2
uniprot id: A0A6J3DRT4
names: Function
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

219594:EFHC1
gene id: 219594:EFHC1
uniprot id: A0A6J3CRM4
uniprot id: A0A6J3CTY6
names: Subcellular Location Annotation
messages: cilium axoneme

219594:RALB
gene id: 219594:RALB
uniprot id: A0A6J3D688
names: Similarity
messages: Belongs to the small GTPase superfamily. Ras family.

219594:TCTA
gene id: 219594:TCTA
uniprot id: A0A6J3DLA5
names: Similarity
messages: Belongs to the TCTA family.

219594:MUC4
gene id: 219594:MUC4
uniprot id: A0A6J3DHZ7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:IDO2
gene id: 219594:IDO2
uniprot id: A0A6J3EAC1
names: Similarity
messages: Belongs to the indoleamine 2,3-dioxygenase family.

219594:GFRA2
gene id: 219594:GFRA2
uniprot id: A0A6J3EDP0
uniprot id: A0A6J3EFD5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GDNFR family.
messages: Cell membrane
messages: Membrane
messages: Receptor for neurturin. Mediates the NRTN-induced autophosphorylation and activation of the RET receptor. Also able to mediate GDNF signaling through the RET tyrosine kinase receptor.

219594:NRG4
gene id: 219594:NRG4
uniprot id: A0A6J3DHU1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neuregulin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

219594:CSTF2
gene id: 219594:CSTF2
uniprot id: A0A6J3DLY3
uniprot id: A0A6J3DS54
names: Subcellular Location Annotation
messages: Nucleus

219594:PRMT7
gene id: 219594:PRMT7
uniprot id: A0A6J3DQI6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA), with a preference for the formation of MMA. Specifically mediates the symmetrical dimethylation of arginine residues in the small nuclear ribonucleoproteins Sm D1 (SNRPD1) and Sm D3 (SNRPD3); such methylation being required for the assembly and biogenesis of snRNP core particles. Specifically mediates the symmetric dimethylation of histone H4 'Arg-3' to form H4R3me2s. Plays a role in gene imprinting by being recruited by CTCFL at the H19 imprinted control region (ICR) and methylating histone H4 to form H4R3me2s, possibly leading to recruit DNA methyltransferases at these sites. May also play a role in embryonic stem cell (ESC) pluripotency. Also able to mediate the arginine methylation of histone H2A and myelin basic protein (MBP) in vitro; the relevance of such results is however unclear in vivo.
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. PRMT7 subfamily.
messages: Nucleus
messages: cytosol

219594:LOC116490160
gene id: 219594:LOC116490160
uniprot id: A0A6J3D3S9
names: Similarity
messages: Belongs to the peptidase A1 family.

219594:ADRA2C
gene id: 219594:ADRA2C
uniprot id: A0A6J3CZ51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:NUDT6
gene id: 219594:NUDT6
uniprot id: A0A6J3CY33
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Nudix hydrolase family.
messages: Cytoplasm
messages: May contribute to the regulation of cell proliferation.
messages: Mitochondrion
messages: Monomer and homodimer.
messages: Nucleus

219594:RSPH3
gene id: 219594:RSPH3
uniprot id: A0A6J3CSR1
names: Similarity
messages: Belongs to the flagellar radial spoke RSP3 family.

219594:KIZ
gene id: 219594:KIZ
uniprot id: A0A6J3CKL9
uniprot id: A0A6J3CM71
uniprot id: A0A6J3CNA1
uniprot id: A0A6J3CRK0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the kizuna family.
messages: Centrosomal protein required for establishing a robust mitotic centrosome architecture that can endure the forces that converge on the centrosomes during spindle formation. Required for stabilizing the expanded pericentriolar material around the centriole.
messages: centrosome
messages: cilium basal body

219594:ENTR1
gene id: 219594:ENTR1
uniprot id: A0A6J3DZS2
names: Similarity
messages: Belongs to the ENTR1 family.

219594:IQCD
gene id: 219594:IQCD
uniprot id: A0A6J3DZN3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DRC10 family.
messages: Component of the nexin-dynein regulatory complex (N-DRC), a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes.
messages: flagellum axoneme

219594:NIPBL
gene id: 219594:NIPBL
uniprot id: A0A6J3ECF0
uniprot id: A0A6J3EDS3
uniprot id: A0A6J3EH88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCC2/Nipped-B family.
messages: Nucleus

219594:LOC116491966
gene id: 219594:LOC116491966
uniprot id: A0A6J3DCJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FMO family.
messages: Endoplasmic reticulum membrane
messages: Microsome membrane

219594:LOC116494267
gene id: 219594:LOC116494267
uniprot id: A0A6J3DMU0
uniprot id: A0A6J3DPM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
messages: Membrane

219594:UNC45A
gene id: 219594:UNC45A
uniprot id: A0A6J3DGQ9
names: Subcellular Location Annotation
messages: perinuclear region

219594:GABRA4
gene id: 219594:GABRA4
uniprot id: A0A6J3CZR9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

219594:C12H19orf12
gene id: 219594:C12H19orf12
uniprot id: A0A6J3DQG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the C19orf12 family.
messages: Mitochondrion membrane

219594:LMOD1
gene id: 219594:LMOD1
uniprot id: A0A6J3E5I7
names: Subcellular Location Annotation
messages: cytoskeleton
messages: sarcomere

219594:FSIP1
gene id: 219594:FSIP1
uniprot id: A0A6J3CZ34
names: Similarity
messages: Belongs to the FSIP1 family.

219594:ENPEP
gene id: 219594:ENPEP
uniprot id: A0A6J3D0Q1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homodimer; disulfide-linked.

219594:DPF3
gene id: 219594:DPF3
uniprot id: A0A6J3D0E9
uniprot id: A0A6J3D0F4
uniprot id: A0A6J3D2U8
uniprot id: A0A6J3D329
uniprot id: A0A6J3D334
uniprot id: A0A6J3D6B1
uniprot id: A0A6J3D6B6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the requiem/DPF family.
messages: Nucleus

219594:LOC116497929
gene id: 219594:LOC116497929
uniprot id: A0A6J3E936
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM45 family.
messages: Membrane

219594:LOC116491607
gene id: 219594:LOC116491607
uniprot id: A0A6J3D852
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Conversion of pregnenolone and progesterone to their 17-alpha-hydroxylated products and subsequently to dehydroepiandrosterone (DHEA) and androstenedione. Catalyzes both the 17-alpha-hydroxylation and the 17,20-lyase reaction.
messages: Membrane

219594:KIF15
gene id: 219594:KIF15
uniprot id: A0A6J3CL00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
messages: spindle

219594:LOC116485683
gene id: 219594:LOC116485683
uniprot id: A0A6J3CF63
names: Similarity
names: Subunit
messages: Belongs to the avian keratin family.
messages: The avian keratins (F-ker, S-ker, C-ker and B-ker) are a complex mixture of very similar polypeptides.

219594:SIN3A
gene id: 219594:SIN3A
uniprot id: A0A6J3DKK0
uniprot id: A0A6J3DNG7
names: Subcellular Location Annotation
messages: Nucleus

219594:LPCAT2
gene id: 219594:LPCAT2
uniprot id: A0A6J3DQB1
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

219594:LOC116490528
gene id: 219594:LOC116490528
uniprot id: A0A6J3D8R3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium channel (TC 1.A.1.10) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.
messages: Membrane

219594:RPA3
gene id: 219594:RPA3
uniprot id: A0A6J3CI89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the replication factor A protein 3 family.
messages: Nucleus

219594:LOC116496235
gene id: 219594:LOC116496235
uniprot id: A0A6J3DWG3
uniprot id: A0A6J3DZI9
uniprot id: A0A6J3E0J6
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

219594:TIMELESS
gene id: 219594:TIMELESS
uniprot id: A0A6J3EF66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the timeless family.
messages: Nucleus

219594:FABP3
gene id: 219594:FABP3
uniprot id: A0A6J3E378
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

219594:HMGA2
gene id: 219594:HMGA2
uniprot id: A0A6J3EHU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HMGA family.
messages: Nucleus

219594:PRIM2
gene id: 219594:PRIM2
uniprot id: A0A6J3CRG7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the eukaryotic-type primase large subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Regulatory subunit of the DNA primase complex and component of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which play an essential role in the initiation of DNA synthesis. The primase subunit of the polymerase alpha complex initiates DNA synthesis by oligomerising short RNA primers on both leading and lagging strands.

219594:LOC116500448
gene id: 219594:LOC116500448
uniprot id: A0A6J3ECD7
uniprot id: A0A6J3EDR8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

219594:N6AMT1
gene id: 219594:N6AMT1
uniprot id: A0A6J3EKC9
names: Similarity
messages: Belongs to the eukaryotic/archaeal PrmC-related family.

219594:P2RY2
gene id: 219594:P2RY2
uniprot id: A0A6J3EQW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:SERINC2
gene id: 219594:SERINC2
uniprot id: A0A6J3E7W0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TDE1 family.
messages: Membrane

219594:SERPINC1
gene id: 219594:SERPINC1
uniprot id: A0A6J3DG84
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the serpin family.
messages: Forms protease inhibiting heterodimer with TMPRSS7.
messages: extracellular space

219594:MGA
gene id: 219594:MGA
uniprot id: A0A6J3D0Z5
uniprot id: A0A6J3D3C6
uniprot id: A0A6J3D3M5
uniprot id: A0A6J3D5W8
uniprot id: A0A6J3D5X3
uniprot id: A0A6J3D6T3
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

219594:REV1
gene id: 219594:REV1
uniprot id: A0A6J3DPP3
uniprot id: A0A6J3DRX3
uniprot id: A0A6J3DVR9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-Y family.
messages: Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template-dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents.
messages: Nucleus

219594:LYZ
gene id: 219594:LYZ
uniprot id: A0A6J3ED48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 22 family.
messages: Secreted

219594:DPP4
gene id: 219594:DPP4
uniprot id: A0A6J3D8S7
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the peptidase S9B family. DPPIV subfamily.
messages: Cell junction
messages: Cell membrane
messages: Membrane raft
messages: invadopodium membrane
messages: lamellipodium membrane

219594:OPTN
gene id: 219594:OPTN
uniprot id: A0A6J3DU05
names: Function
names: Subcellular Location Annotation
messages: Cytoplasmic vesicle
messages: Endosome
messages: Golgi apparatus
messages: May act by regulating membrane trafficking and cellular morphogenesis.
messages: Recycling endosome
messages: Vesicle
messages: autophagosome
messages: perinuclear region
messages: trans-Golgi network

219594:MMP15
gene id: 219594:MMP15
uniprot id: A0A6J3DNE7
names: Similarity
messages: Belongs to the peptidase M10A family.

219594:LOC116489480
gene id: 219594:LOC116489480
uniprot id: A0A6J3D014
names: Similarity
messages: Belongs to the serpin family.

219594:LOC116491361
gene id: 219594:LOC116491361
uniprot id: A0A6J3DCR8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:MPP5
gene id: 219594:MPP5
uniprot id: A0A6J3D2K7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAGUK family.
messages: Cell membrane
messages: tight junction

219594:ZER1
gene id: 219594:ZER1
uniprot id: A0A6J3DZ65
names: Similarity
messages: Belongs to the zyg-11 family.

219594:PDE8A
gene id: 219594:PDE8A
uniprot id: A0A6J3DGY9
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family. PDE8 subfamily.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

219594:CHGB
gene id: 219594:CHGB
uniprot id: A0A6J3CLV4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromogranin/secretogranin protein family.
messages: Secreted

219594:ST7L
gene id: 219594:ST7L
uniprot id: A0A6J3EC10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ST7 family.
messages: Membrane

219594:SRP54
gene id: 219594:SRP54
uniprot id: A0A6J3D1I6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Component of a signal recognition particle (SRP) complex that consists of a 7SL RNA molecule of 300 nucleotides and six protein subunits: SRP72, SRP68, SRP54, SRP19, SRP14 and SRP9.
messages: Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER). Binds to the signal sequence of presecretory proteins when they emerge from the ribosomes.
messages: Cytoplasm
messages: Has a two domain structure: the G-domain binds GTP; the M-domain binds the 7S RNA in presence of SRP19 and also binds the signal sequence.
messages: Nucleus speckle
messages: Signal recognition particle consists of a 7S RNA molecule and at least six protein subunits.

219594:CLN8
gene id: 219594:CLN8
uniprot id: A0A6J3CPK9
names: Subcellular Location Annotation
messages: Membrane

219594:DCN
gene id: 219594:DCN
uniprot id: A0A6J3CND0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily.
messages: Binds to type I and type II collagen, fibronectin and TGF-beta. Forms a ternary complex with MFAP2 and ELN.
messages: May affect the rate of fibrils formation.
messages: extracellular matrix

219594:CRELD1
gene id: 219594:CRELD1
uniprot id: A0A6J3DEG4
names: Caution
names: Similarity
messages: Belongs to the CRELD family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:RGMB
gene id: 219594:RGMB
uniprot id: A0A6J3EEJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the repulsive guidance molecule (RGM) family.
messages: Cell membrane
messages: Membrane

219594:PLXND1
gene id: 219594:PLXND1
uniprot id: A0A6J3DJA3
names: Caution
names: Similarity
messages: Belongs to the plexin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:PEMT
gene id: 219594:PEMT
uniprot id: A0A6J3DQN1
uniprot id: A0A6J3DVW9
uniprot id: A0A6J3DWT1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class VI-like SAM-binding methyltransferase superfamily. PEMT/PEM2 methyltransferase family.
messages: Catalyzes the three sequential steps of the methylation pathway for the biosynthesis of phosphatidylcholine, a critical and essential component for membrane structure. Uses S-adenosylmethionine (S-adenosyl-L-methionine, SAM or AdoMet) as the methyl group donor for the methylation of phosphatidylethanolamine (1,2-diacyl-sn-glycero-3-phosphoethanolamine, PE) to phosphatidylmonomethylethanolamine (1,2-diacyl-sn-glycero-3-phospho-N-methylethanolamine, PMME), PMME to phosphatidyldimethylethanolamine (1,2-diacyl-sn-glycero-3-phospho-N,N-dimethylethanolamine, PDME), and PDME to phosphatidylcholine (1,2-diacyl-sn-glycero-3-phosphocholine, PC), producing S-adenosyl-L-homocysteine in each step.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Mitochondrion membrane

219594:VWA2
gene id: 219594:VWA2
uniprot id: A0A6J3DCQ8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:E2F4
gene id: 219594:E2F4
uniprot id: A0A6J3DMP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the E2F/DP family.
messages: Nucleus

219594:EPS8L3
gene id: 219594:EPS8L3
uniprot id: A0A6J3E6Z9
names: Similarity
messages: Belongs to the EPS8 family.

219594:LOC116496542
gene id: 219594:LOC116496542
uniprot id: A0A6J3DW56
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: High affinity receptor for urotensin-2 and urotensin-2B. The activity of this receptor is mediated by a G-protein that activate a phosphatidylinositol-calcium second messenger system.
messages: Membrane

219594:SMARCAD1
gene id: 219594:SMARCAD1
uniprot id: A0A6J3CVZ1
names: Subcellular Location Annotation
messages: Chromosome

219594:LOC116486620
gene id: 219594:LOC116486620
uniprot id: A0A6J3CPU8
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

219594:PPP1R21
gene id: 219594:PPP1R21
uniprot id: A0A6J3CU49
names: Subcellular Location Annotation
messages: Early endosome
messages: Endosome

219594:HOXC5
gene id: 219594:HOXC5
uniprot id: A0A6J3EBY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus

219594:TRMT2A
gene id: 219594:TRMT2A
uniprot id: A0A6J3DZ71
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:DDX58
gene id: 219594:DDX58
uniprot id: A0A6J3EIR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the helicase family. RLR subfamily.
messages: Cytoplasm

219594:LOC116500313
gene id: 219594:LOC116500313
uniprot id: A0A6J3EIC6
names: Subcellular Location Annotation
messages: Membrane

219594:C17H12orf65
gene id: 219594:C17H12orf65
uniprot id: A0A6J3DYX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Mitochondrion

219594:TUBGCP3
gene id: 219594:TUBGCP3
uniprot id: A0A6J3DY84
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TUBGCP family.
messages: Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome.
messages: centrosome

219594:LRRFIP1
gene id: 219594:LRRFIP1
uniprot id: A0A6J3D440
uniprot id: A0A6J3D6Q7
uniprot id: A0A6J3D6R1
uniprot id: A0A6J3D788
uniprot id: A0A6J3D793
uniprot id: A0A6J3D9G2
uniprot id: A0A6J3DA06
uniprot id: A0A6J3DA11
names: Similarity
messages: Belongs to the LRRFIP family.

219594:LOC116489454
gene id: 219594:LOC116489454
uniprot id: A0A6J3CZY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ITPRIP family.
messages: Membrane

219594:PLXNA4
gene id: 219594:PLXNA4
uniprot id: A0A6J3E8Y1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the plexin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

219594:PTGS1
gene id: 219594:PTGS1
uniprot id: A0A6J3E4G2
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the prostaglandin G/H synthase family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:MME
gene id: 219594:MME
uniprot id: A0A6J3DIY5
names: Cofactor
messages: Binds 1 zinc ion per subunit.

219594:TRMT13
gene id: 219594:TRMT13
uniprot id: A0A6J3D8I7
names: Function
names: Similarity
messages: Belongs to the methyltransferase TRM13 family.
messages: tRNA methylase which 2'-O-methylates cytidine(4) in tRNA(Pro) and tRNA(Gly)(GCC), and adenosine(4) in tRNA(His).

219594:SUFU
gene id: 219594:SUFU
uniprot id: A0A6J3D732
uniprot id: A0A6J3DAG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUFU family.
messages: Cytoplasm
messages: Nucleus

219594:ATP1B1
gene id: 219594:ATP1B1
uniprot id: A0A6J3CPY7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the X(+)/potassium ATPases subunit beta family.
messages: Cell membrane
messages: Membrane
messages: This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane.

219594:PPIA
gene id: 219594:PPIA
uniprot id: A0A6J3E8E1
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

219594:LOC116485530
gene id: 219594:LOC116485530
uniprot id: A0A6J3CJA7
names: Similarity
messages: Belongs to the cytochrome P450 family.

219594:MAPKAPK2
gene id: 219594:MAPKAPK2
uniprot id: A0A6J3EAB1
names: Similarity
messages: Belongs to the protein kinase superfamily.

219594:ENTPD4
gene id: 219594:ENTPD4
uniprot id: A0A6J3EDU4
uniprot id: A0A6J3EFI9
names: Similarity
messages: Belongs to the GDA1/CD39 NTPase family.

219594:LOC116501300
gene id: 219594:LOC116501300
uniprot id: A0A6J3ELD2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:DYRK2
gene id: 219594:DYRK2
uniprot id: A0A6J3DB73
uniprot id: A0A6J3DDT9
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MNB/DYRK subfamily.

219594:CFAP36
gene id: 219594:CFAP36
uniprot id: A0A6J3CR74
names: Similarity
messages: Belongs to the CFAP36 family.

219594:MEIS2
gene id: 219594:MEIS2
uniprot id: A0A6J3D252
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/MEIS homeobox family.
messages: Nucleus

219594:IL26
gene id: 219594:IL26
uniprot id: A0A6J3E682
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-10 family.
messages: Immune regulatory cytokine.
messages: Secreted

219594:STK4
gene id: 219594:STK4
uniprot id: A0A6J3DS03
uniprot id: A0A6J3DX43
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.
messages: Nucleus

219594:RSBN1
gene id: 219594:RSBN1
uniprot id: A0A6J3E5G2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the round spermatid basic protein 1 family.
messages: Nucleus

219594:MRPS30
gene id: 219594:MRPS30
uniprot id: A0A6J3EKJ8
names: Subcellular Location Annotation
messages: Mitochondrion

219594:RER1
gene id: 219594:RER1
uniprot id: A0A6J3E5M4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RER1 family.
messages: Involved in the retrieval of endoplasmic reticulum membrane proteins from the early Golgi compartment.
messages: Membrane

219594:ST8SIA3
gene id: 219594:ST8SIA3
uniprot id: A0A6J3EDT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

219594:BTG4
gene id: 219594:BTG4
uniprot id: A0A6J3E2V9
names: Similarity
messages: Belongs to the BTG family.

219594:LOC116496138
gene id: 219594:LOC116496138
uniprot id: A0A6J3E070
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

219594:CD38
gene id: 219594:CD38
uniprot id: A0A6J3CWA1
uniprot id: A0A6J3CYH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADP-ribosyl cyclase family.
messages: Membrane

219594:LOC116501332
gene id: 219594:LOC116501332
uniprot id: A0A6J3ELG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:CNIH1
gene id: 219594:CNIH1
uniprot id: A0A6J3D2H2
uniprot id: A0A6J3D2P2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cornichon family.
messages: Membrane

219594:LOC116491118
gene id: 219594:LOC116491118
uniprot id: A0A6J3D8H0
uniprot id: A0A6J3D8Z5
names: Similarity
messages: Belongs to the hexokinase family.

219594:LOC116494755
gene id: 219594:LOC116494755
uniprot id: A0A6J3DPY4
uniprot id: A0A6J3DRY7
uniprot id: A0A6J3DSQ1
uniprot id: A0A6J3DTT7
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain.

219594:PPP1R12A
gene id: 219594:PPP1R12A
uniprot id: A0A6J3E074
uniprot id: A0A6J3E4E9
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: PP1 comprises a catalytic subunit, and one or several targeting or regulatory subunits.

219594:CELF3
gene id: 219594:CELF3
uniprot id: A0A6J3EER0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CELF/BRUNOL family.
messages: Cytoplasm
messages: Nucleus

219594:GORASP2
gene id: 219594:GORASP2
uniprot id: A0A6J3DAA0
names: Similarity
messages: Belongs to the GORASP family.

219594:LOC116500341
gene id: 219594:LOC116500341
uniprot id: A0A6J3EIF1
names: Subcellular Location Annotation
messages: Membrane

219594:PROK1
gene id: 219594:PROK1
uniprot id: A0A6J3EAM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AVIT (prokineticin) family.
messages: Secreted

219594:NKX2-3
gene id: 219594:NKX2-3
uniprot id: A0A6J3DBC0
uniprot id: A0A6J3DDV8
names: Subcellular Location Annotation
messages: Nucleus

219594:CHPF2
gene id: 219594:CHPF2
uniprot id: A0A6J3CGG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chondroitin N-acetylgalactosaminyltransferase family.
messages: Golgi stack membrane
messages: Membrane

219594:LOC116500120
gene id: 219594:LOC116500120
uniprot id: A0A6J3EB60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:CRB2
gene id: 219594:CRB2
uniprot id: A0A6J3DXF4
uniprot id: A0A6J3E1L0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:KCNK12
gene id: 219594:KCNK12
uniprot id: A0A6J3CS95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

219594:DHX30
gene id: 219594:DHX30
uniprot id: A0A6J3CK80
uniprot id: A0A6J3CLG0
uniprot id: A0A6J3CND8
names: Similarity
messages: Belongs to the DEAD box helicase family. DEAH subfamily.

219594:DOCK10
gene id: 219594:DOCK10
uniprot id: A0A6J3DBF8
uniprot id: A0A6J3DBG3
uniprot id: A0A6J3DBG8
uniprot id: A0A6J3DE18
uniprot id: A0A6J3DE27
uniprot id: A0A6J3DE32
uniprot id: A0A6J3DF65
uniprot id: A0A6J3DF72
uniprot id: A0A6J3DF79
uniprot id: A0A6J3DGZ1
uniprot id: A0A6J3DGZ6
uniprot id: A0A6J3DH01
uniprot id: A0A6J3DHF6
uniprot id: A0A6J3DHG1
uniprot id: A0A6J3DHG7
uniprot id: A0A6J3DHH5
names: Similarity
messages: Belongs to the DOCK family.

219594:RBFOX1
gene id: 219594:RBFOX1
uniprot id: A0A6J3DQX0
uniprot id: A0A6J3DQY3
uniprot id: A0A6J3DQY9
uniprot id: A0A6J3DQZ3
uniprot id: A0A6J3DT60
uniprot id: A0A6J3DT68
uniprot id: A0A6J3DT75
uniprot id: A0A6J3DT82
uniprot id: A0A6J3DVA1
uniprot id: A0A6J3DVA9
uniprot id: A0A6J3DVB8
uniprot id: A0A6J3DVC3
uniprot id: A0A6J3DVC7
uniprot id: A0A6J3DW64
uniprot id: A0A6J3DW69
uniprot id: A0A6J3DX31
uniprot id: A0A6J3DX36
uniprot id: A0A6J3DX41
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: RNA-binding protein that regulates alternative splicing events.

219594:USP7
gene id: 219594:USP7
uniprot id: A0A6J3DV99
names: Similarity
messages: Belongs to the peptidase C19 family.

219594:ISCA1
gene id: 219594:ISCA1
uniprot id: A0A6J3EKU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HesB/IscA family.
messages: Mitochondrion

219594:CLGN
gene id: 219594:CLGN
uniprot id: A0A6J3CYK4
uniprot id: A0A6J3CYW8
names: Similarity
messages: Belongs to the calreticulin family.

219594:CHRNA3
gene id: 219594:CHRNA3
uniprot id: A0A6J3DGN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

219594:EFEMP1
gene id: 219594:EFEMP1
uniprot id: A0A6J3CT84
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:SLC15A1
gene id: 219594:SLC15A1
uniprot id: A0A6J3E807
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Interacts (via extracellular domain region) with trypsin.
messages: Membrane

219594:AMOTL2
gene id: 219594:AMOTL2
uniprot id: A0A6J3DIP9
names: Similarity
messages: Belongs to the angiomotin family.

219594:HSPA8
gene id: 219594:HSPA8
uniprot id: A0A6J3E6E8
names: Similarity
messages: Belongs to the heat shock protein 70 family.

219594:ADCYAP1R1
gene id: 219594:ADCYAP1R1
uniprot id: A0A6J3CIE4
uniprot id: A0A6J3CJV1
uniprot id: A0A6J3CN03
uniprot id: A0A6J3CPF4
uniprot id: A0A6J3CPF9
names: Subcellular Location Annotation
messages: Membrane

219594:CDC6
gene id: 219594:CDC6
uniprot id: A0A6J3E445
names: Similarity
messages: Belongs to the CDC6/cdc18 family.

219594:DYM
gene id: 219594:DYM
uniprot id: A0A6J3EC59
names: Similarity
messages: Belongs to the dymeclin family.

219594:CEP19
gene id: 219594:CEP19
uniprot id: A0A6J3DDR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CEP19 family.
messages: centriole
messages: cilium basal body
messages: spindle pole

219594:ADCY6
gene id: 219594:ADCY6
uniprot id: A0A6J3EH60
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Binds 2 magnesium ions per subunit. Is also active with manganese (in vitro).
messages: Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.
messages: Membrane

219594:MAP6D1
gene id: 219594:MAP6D1
uniprot id: A0A6J3DDM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STOP family.
messages: cytoskeleton

219594:KCNK2
gene id: 219594:KCNK2
uniprot id: A0A6J3CTC8
uniprot id: A0A6J3CTU1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

219594:ATP5F1C
gene id: 219594:ATP5F1C
uniprot id: A0A6J3EGD3
uniprot id: A0A6J3EK56
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(1) domain and the central stalk which is part of the complex rotary element. The gamma subunit protrudes into the catalytic domain formed of alpha(3)beta(3). Rotation of the central stalk against the surrounding alpha(3)beta(3) subunits leads to hydrolysis of ATP in three separate catalytic sites on the beta subunits.

219594:LOC116497330
gene id: 219594:LOC116497330
uniprot id: A0A6J3E623
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine beta (chemokine CC) family.
messages: Secreted

219594:LOC116500333
gene id: 219594:LOC116500333
uniprot id: A0A6J3EGU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:LOC116499751
gene id: 219594:LOC116499751
uniprot id: A0A6J3E9U3
names: Similarity
names: Subunit
messages: Belongs to the avian keratin family.
messages: The avian keratins (F-ker, S-ker, C-ker and B-ker) are a complex mixture of very similar polypeptides.

219594:HS2ST1
gene id: 219594:HS2ST1
uniprot id: A0A6J3DGD5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 3 family.
messages: Membrane

219594:LOC116489463
gene id: 219594:LOC116489463
uniprot id: A0A6J3CZU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ITPRIP family.
messages: Membrane

219594:GCM2
gene id: 219594:GCM2
uniprot id: A0A6J3CD98
names: Subcellular Location Annotation
messages: Nucleus

219594:LOC116490575
gene id: 219594:LOC116490575
uniprot id: A0A6J3D8B8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone deacetylase family. HD type 2 subfamily.
messages: Nucleus
messages: Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.

219594:HTR6
gene id: 219594:HTR6
uniprot id: A0A6J3E7D5
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

219594:LMLN
gene id: 219594:LMLN
uniprot id: A0A6J3D6M4
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M8 family.
messages: Binds 1 zinc ion per subunit.

219594:MMRN1
gene id: 219594:MMRN1
uniprot id: A0A6J3CZG5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:TSN
gene id: 219594:TSN
uniprot id: A0A6J3DA63
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the translin family.
messages: DNA-binding protein that specifically recognizes consensus sequences at the breakpoint junctions in chromosomal translocations, mostly involving immunoglobulin (Ig)/T-cell receptor gene segments. Seems to recognize single-stranded DNA ends generated by staggered breaks occurring at recombination hot spots.
messages: Exhibits both single-stranded and double-stranded endoribonuclease activity. May act as an activator of RNA-induced silencing complex (RISC) by facilitating endonucleolytic cleavage of the siRNA passenger strand.
messages: Nucleus
messages: Ring-shaped heterooctamer of six TSN and two TSNAX subunits, DNA/RNA binding occurs inside the ring.

219594:GGT5
gene id: 219594:GGT5
uniprot id: A0A6J3DZU0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaves the gamma-glutamyl peptide bond of glutathione and glutathione conjugates.
messages: Membrane

219594:TNFAIP3
gene id: 219594:TNFAIP3
uniprot id: A0A6J3CWS8
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

219594:SLC7A4
gene id: 219594:SLC7A4
uniprot id: A0A6J3E1D1
names: Subcellular Location Annotation
messages: Membrane

219594:SNAP25
gene id: 219594:SNAP25
uniprot id: A0A6J3CPB0
uniprot id: A0A6J3CQ47
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNAP-25 family.
messages: Cell membrane
messages: Plays an important role in the synaptic function of specific neuronal systems. Associates with proteins involved in vesicle docking and membrane fusion.
messages: synaptosome

219594:ARV1
gene id: 219594:ARV1
uniprot id: A0A6J3CSX7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ARV1 family.
messages: Endoplasmic reticulum membrane
messages: Mediator of sterol homeostasis involved in sterol uptake, trafficking and distribution into membranes.
messages: Membrane

219594:RAX
gene id: 219594:RAX
uniprot id: A0A6J3EGS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paired homeobox family. Bicoid subfamily.
messages: Nucleus

219594:ZC3H12C
gene id: 219594:ZC3H12C
uniprot id: A0A6J3EQK8
names: Similarity
messages: Belongs to the ZC3H12 family.

219594:LOC116500971
gene id: 219594:LOC116500971
uniprot id: A0A6J3EJY8
names: Similarity
messages: Belongs to the actin family.

219594:CCDC39
gene id: 219594:CCDC39
uniprot id: A0A6J3DHA8
uniprot id: A0A6J3DHV2
names: Similarity
messages: Belongs to the CCDC39 family.

219594:LONP2
gene id: 219594:LONP2
uniprot id: A0A6J3DLA3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: ATP-dependent serine protease that mediates the selective degradation of misfolded and unassembled polypeptides in the peroxisomal matrix. Necessary for type 2 peroxisome targeting signal (PTS2)-containing protein processing and facilitates peroxisome matrix protein import.
messages: Belongs to the peptidase S16 family.
messages: Peroxisome matrix

219594:HSPA13
gene id: 219594:HSPA13
uniprot id: A0A6J3DY29
uniprot id: A0A6J3DY39
names: Similarity
messages: Belongs to the heat shock protein 70 family.

219594:LOC116487630
gene id: 219594:LOC116487630
uniprot id: A0A6J3CNJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
messages: cytoskeleton

219594:TK1
gene id: 219594:TK1
uniprot id: A0A6J3E2I2
names: Similarity
messages: Belongs to the thymidine kinase family.

219594:DPH6
gene id: 219594:DPH6
uniprot id: A0A6J3D0S9
uniprot id: A0A6J3D6M3
names: Similarity
messages: Belongs to the Diphthine--ammonia ligase family.

219594:FLVCR1
gene id: 219594:FLVCR1
uniprot id: A0A6J3CTS2
names: Subcellular Location Annotation
messages: Membrane

219594:AKR1A1
gene id: 219594:AKR1A1
uniprot id: A0A6J3DED1
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the aldo/keto reductase family.
messages: Cell membrane
messages: Membrane
messages: cytosol

219594:PARN
gene id: 219594:PARN
uniprot id: A0A6J3DNW2
uniprot id: A0A6J3DT58
uniprot id: A0A6J3DT63
uniprot id: A0A6J3DU43
uniprot id: A0A6J3DUZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAF1 family.
messages: Cytoplasm
messages: Nucleus

219594:PIK3C2A
gene id: 219594:PIK3C2A
uniprot id: A0A6J3CXW6
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.

219594:TSNAX
gene id: 219594:TSNAX
uniprot id: A0A6J3CQA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the translin family.
messages: Nucleus

219594:ALG9
gene id: 219594:ALG9
uniprot id: A0A6J3E3Y4
uniprot id: A0A6J3E6U0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 22 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

219594:ARL11
gene id: 219594:ARL11
uniprot id: A0A6J3ELF0
uniprot id: A0A6J3ERW9
names: Similarity
messages: Belongs to the small GTPase superfamily. Arf family.

219594:MRPL28
gene id: 219594:MRPL28
uniprot id: A0A6J3DV17
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

219594:CCDC93
gene id: 219594:CCDC93
uniprot id: A0A6J3D6S0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCDC93 family.
messages: Early endosome

219594:ABCG4
gene id: 219594:ABCG4
uniprot id: A0A6J3E2H5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCG family. Eye pigment precursor importer (TC 3.A.1.204) subfamily.
messages: Membrane

219594:TRMT44
gene id: 219594:TRMT44
uniprot id: A0A6J3D1C7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Adenosyl-L-methionine (AdoMet)-dependent tRNA (uracil-O(2)-)-methyltransferase.
messages: Belongs to the TRM44 family.
messages: Cytoplasm
messages: Probable adenosyl-L-methionine (AdoMet)-dependent tRNA (uracil-O(2)-)-methyltransferase.

219594:MARF1
gene id: 219594:MARF1
uniprot id: A0A6J3DP78
uniprot id: A0A6J3DUH3
names: Subcellular Location Annotation
messages: Peroxisome

219594:LOC116492538
gene id: 219594:LOC116492538
uniprot id: A0A6J3DCJ7
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

219594:VPS51
gene id: 219594:VPS51
uniprot id: A0A6J3D7T5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the VPS51 family.
messages: Component of the Golgi-associated retrograde protein (GARP) complex. Component of the endosome-associated retrograde protein (EARP) complex.
messages: Involved in retrograde transport from early and late endosomes to the late Golgi. The GARP complex is required for the maintenance of protein retrieval from endosomes to the TGN, acid hydrolase sorting, lysosome function, endosomal cholesterol traffic and autophagy. Acts as component of the EARP complex that is involved in endocytic recycling.
messages: Recycling endosome
messages: trans-Golgi network

219594:PPP1R9B
gene id: 219594:PPP1R9B
uniprot id: A0A6J3E611
uniprot id: A0A6J3E906
names: Subcellular Location Annotation
messages: cytoskeleton

219594:LOC116493946
gene id: 219594:LOC116493946
uniprot id: A0A6J3DPN0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the p22phox family.
messages: Cell membrane
messages: Composed of a heavy chain (beta) and a light chain (alpha). Component of an NADPH oxidase complex composed of a heterodimer formed by the membrane proteins CYBA and CYBB and the cytosolic subunits NCF1, NCF2 and NCF4. Interacts with NCF1 (via SH3 domain).
messages: Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. Associates with NOX3 to form a functional NADPH oxidase constitutively generating superoxide.
messages: Membrane

219594:GLUL
gene id: 219594:GLUL
uniprot id: A0A6J3DD65
names: Similarity
messages: Belongs to the glutamine synthetase family.

219594:PCMT1
gene id: 219594:PCMT1
uniprot id: A0A6J3CRI3
uniprot id: A0A6J3CXQ3
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

219594:RPSA
gene id: 219594:RPSA
uniprot id: A0A6J3CL21
names: Function
names: Miscellaneous
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acylated. Acylation may be a prerequisite for conversion of the monomeric 37 kDa laminin receptor precursor (37LRP) to the mature dimeric 67 kDa laminin receptor (67LR), and may provide a mechanism for membrane association.
messages: Belongs to the universal ribosomal protein uS2 family.
messages: Cell membrane
messages: Cleaved by stromelysin-3 (ST3) at the cell surface. Cleavage by stromelysin-3 may be a mechanism to alter cell-extracellular matrix interactions.
messages: Cytoplasm
messages: Monomer (37LRP) and homodimer (67LR). Component of the small ribosomal subunit. Mature ribosomes consist of a small (40S) and a large (60S) subunit. The 40S subunit contains about 33 different proteins and 1 molecule of RNA (18S). The 60S subunit contains about 49 different proteins and 3 molecules of RNA (28S, 5.8S and 5S). Interacts with RPS21. Interacts with several laminins including at least LAMB1. Interacts with MDK.
messages: Nucleus
messages: Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits. Also functions as a cell surface receptor for laminin. Plays a role in cell adhesion to the basement membrane and in the consequent activation of signaling transduction pathways. May play a role in cell fate determination and tissue morphogenesis.
messages: This protein appears to have acquired a second function as a laminin receptor specifically in the vertebrate lineage.

219594:NUP210
gene id: 219594:NUP210
uniprot id: A0A6J3DKL3
names: Similarity
messages: Belongs to the NUP210 family.

219594:METRNL
gene id: 219594:METRNL
uniprot id: A0A6J3DYD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the meteorin family.
messages: Secreted

219594:CCT5
gene id: 219594:CCT5
uniprot id: A0A6J3CMW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCP-1 chaperonin family.
messages: Cytoplasm

219594:F2RL3
gene id: 219594:F2RL3
uniprot id: A0A6J3E7W5
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

219594:MICALL1
gene id: 219594:MICALL1
uniprot id: A0A6J3EGQ8
names: Subcellular Location Annotation
messages: Membrane

219594:PHOX2B
gene id: 219594:PHOX2B
uniprot id: A0A6J3CYF5
names: Subcellular Location Annotation
messages: Nucleus

219594:LOC116500144
gene id: 219594:LOC116500144
uniprot id: A0A6J3EHW5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:LOC116491444
gene id: 219594:LOC116491444
uniprot id: A0A6J3DCT2
uniprot id: A0A6J3DD67
names: Similarity
messages: Belongs to the cytochrome P450 family.

219594:NPRL2
gene id: 219594:NPRL2
uniprot id: A0A6J3DIP0
names: Similarity
messages: Belongs to the NPR2 family.

219594:CHST3
gene id: 219594:CHST3
uniprot id: A0A6J3D5C0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 1 family. Gal/GlcNAc/GalNAc subfamily.
messages: Membrane

219594:LOC116497283
gene id: 219594:LOC116497283
uniprot id: A0A6J3E192
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

219594:GUF1
gene id: 219594:GUF1
uniprot id: A0A6J3CU83
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP-binding elongation factor family. LepA subfamily.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Mitochondrion inner membrane
messages: Promotes mitochondrial protein synthesis. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Binds to mitochondrial ribosomes in a GTP-dependent manner.

219594:SMIM19
gene id: 219594:SMIM19
uniprot id: A0A6J3CV07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMIM19 family.
messages: Membrane

219594:NEDD9
gene id: 219594:NEDD9
uniprot id: A0A6J3CMI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAS family.
messages: focal adhesion

219594:LOC116502074
gene id: 219594:LOC116502074
uniprot id: A0A6J3EQL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone H1/H5 family.
messages: Nucleus

219594:LOC116488902
gene id: 219594:LOC116488902
uniprot id: A0A6J3CZM9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

219594:CDK14
gene id: 219594:CDK14
uniprot id: A0A6J3CE77
uniprot id: A0A6J3CFU7
uniprot id: A0A6J3CFV3
uniprot id: A0A6J3CKF6
names: Similarity
messages: Belongs to the protein kinase superfamily.

219594:FATE1
gene id: 219594:FATE1
uniprot id: A0A6J3DS45
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tango11 family.
messages: Membrane
messages: Mitochondrion outer membrane
messages: Peroxisome
messages: Plays a role in mitochondrial and peroxisomal fission. Promotes the recruitment and association of the fission mediator dynamin-related protein 1 (DNM1L) to the mitochondrial surface.

219594:PGR
gene id: 219594:PGR
uniprot id: A0A6J3DVB1
uniprot id: A0A6J3DVC2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Composed of three domains: a modulating N-terminal domain, a DNA-binding domain and a C-terminal ligand-binding domain.
messages: Cytoplasm
messages: Nucleus
messages: Steroid hormone receptor involved in the regulation of eukaryotic gene expression which affects cellular proliferation and differentiation in target tissues.

219594:RNPEPL1
gene id: 219594:RNPEPL1
uniprot id: A0A6J3DH36
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.

219594:IPO5
gene id: 219594:IPO5
uniprot id: A0A6J3DC12
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

219594:LANCL1
gene id: 219594:LANCL1
uniprot id: A0A6J3DA42
names: Similarity
messages: Belongs to the LanC-like protein family.

219594:AFG3L2
gene id: 219594:AFG3L2
uniprot id: A0A6J3CGB3
uniprot id: A0A6J3CI54
names: Similarity
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the N-terminal section; belongs to the AAA ATPase family.

219594:SSH3
gene id: 219594:SSH3
uniprot id: A0A6J3CXR4
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family.

219594:GLCE
gene id: 219594:GLCE
uniprot id: A0A6J3DMY9
uniprot id: A0A6J3DNL2
names: Similarity
messages: Belongs to the D-glucuronyl C5-epimerase family.

219594:ROR2
gene id: 219594:ROR2
uniprot id: A0A6J3EJR4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

219594:ATP2B4
gene id: 219594:ATP2B4
uniprot id: A0A6J3E5P1
uniprot id: A0A6J3E5P4
uniprot id: A0A6J3E746
uniprot id: A0A6J3EA60
uniprot id: A0A6J3EAS7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIB subfamily.
messages: Catalyzes the hydrolysis of ATP coupled with the transport of calcium.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

219594:SESN1
gene id: 219594:SESN1
uniprot id: A0A6J3CLL5
uniprot id: A0A6J3CN99
uniprot id: A0A6J3CP92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sestrin family.
messages: Cytoplasm

219594:SEC11C
gene id: 219594:SEC11C
uniprot id: A0A6J3ELP0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S26B family.
messages: Component of the signal peptidase complex.
messages: Endoplasmic reticulum membrane
messages: Membrane

219594:PARP10
gene id: 219594:PARP10
uniprot id: A0A6J3CF86
names: Similarity
messages: Belongs to the ARTD/PARP family.

219594:LOC116494730
gene id: 219594:LOC116494730
uniprot id: A0A6J3DPU9
names: Similarity
names: Subunit
messages: Belongs to the major facilitator (TC 2.A.1) superfamily. Organic cation transporter (TC 2.A.1.19) family.
messages: Interacts with PDZK1.

219594:LOC116500132
gene id: 219594:LOC116500132
uniprot id: A0A6J3EG87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:SET
gene id: 219594:SET
uniprot id: A0A6J3DZC7
names: Similarity
messages: Belongs to the nucleosome assembly protein (NAP) family.

219594:TRUB1
gene id: 219594:TRUB1
uniprot id: A0A6J3DCA5
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family.

219594:MMP17
gene id: 219594:MMP17
uniprot id: A0A6J3DUR1
uniprot id: A0A6J3DYU3
names: Similarity
messages: Belongs to the peptidase M10A family.

219594:LOC116485681
gene id: 219594:LOC116485681
uniprot id: A0A6J3CI22
names: Similarity
names: Subunit
messages: Belongs to the avian keratin family.
messages: The avian keratins (F-ker, S-ker, C-ker and B-ker) are a complex mixture of very similar polypeptides.

219594:PPP1R15B
gene id: 219594:PPP1R15B
uniprot id: A0A6J3E9Z2
names: Similarity
messages: Belongs to the PPP1R15 family.

219594:LOC116501992
gene id: 219594:LOC116501992
uniprot id: A0A6J3ENT3
names: Similarity
messages: Belongs to the globin family.

219594:CDK5RAP1
gene id: 219594:CDK5RAP1
uniprot id: A0A6J3DXT0
names: Similarity
messages: Belongs to the methylthiotransferase family. MiaB subfamily.

219594:LOC116490404
gene id: 219594:LOC116490404
uniprot id: A0A6J3D785
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

219594:PNMT
gene id: 219594:PNMT
uniprot id: A0A6J3E9M8
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. NNMT/PNMT/TEMT family.

219594:PTGS2
gene id: 219594:PTGS2
uniprot id: A0A6J3DCG6
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the prostaglandin G/H synthase family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Endoplasmic reticulum membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Microsome membrane

219594:MAP3K13
gene id: 219594:MAP3K13
uniprot id: A0A6J3DEX6
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.

219594:GLA
gene id: 219594:GLA
uniprot id: A0A6J3DQR1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycosyl hydrolase 27 family.
messages: Homodimer.
messages: Lysosome

219594:SLC4A10
gene id: 219594:SLC4A10
uniprot id: A0A6J3D2Z7
uniprot id: A0A6J3D5H7
uniprot id: A0A6J3D5I2
uniprot id: A0A6J3D5T3
uniprot id: A0A6J3D829
uniprot id: A0A6J3D8U1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anion exchanger (TC 2.A.31) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

219594:ICMT
gene id: 219594:ICMT
uniprot id: A0A6J3E5Z6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class VI-like SAM-binding methyltransferase superfamily. Isoprenylcysteine carboxyl methyltransferase family.
messages: Catalyzes the post-translational methylation of isoprenylated C-terminal cysteine residues.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

219594:RIMKLB
gene id: 219594:RIMKLB
uniprot id: A0A6J3D475
names: Similarity
messages: Belongs to the RimK family.

219594:COMT
gene id: 219594:COMT
uniprot id: A0A6J3E115
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones.

219594:TIMM44
gene id: 219594:TIMM44
uniprot id: A0A6J3E9B6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tim44 family.
messages: Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner.
messages: Mitochondrion inner membrane

219594:CCDC25
gene id: 219594:CCDC25
uniprot id: A0A6J3CTF8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CCDC25 family.
messages: Cell membrane
messages: Endomembrane system
messages: Interacts (via cytoplasmic region) with ILK.

219594:NCL
gene id: 219594:NCL
uniprot id: A0A6J3DHI5
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleolin is the major nucleolar protein of growing eukaryotic cells. It is found associated with intranucleolar chromatin and pre-ribosomal particles. It induces chromatin decondensation by binding to histone H1. It is thought to play a role in pre-rRNA transcription and ribosome assembly. May play a role in the process of transcriptional elongation. Binds RNA oligonucleotides with 5'-UUAGGG-3' repeats more tightly than the telomeric single-stranded DNA 5'-TTAGGG-3' repeats.
messages: nucleolus

219594:MCM4
gene id: 219594:MCM4
uniprot id: A0A6J3CJJ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.
messages: Belongs to the MCM family.
messages: Chromosome
messages: Component of the MCM2-7 complex.
messages: Nucleus

219594:WDR3
gene id: 219594:WDR3
uniprot id: A0A6J3DK34
names: Subcellular Location Annotation
messages: nucleolus

219594:SEMA3A
gene id: 219594:SEMA3A
uniprot id: A0A6J3CEW5
names: Caution
names: Similarity
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:AGAP3
gene id: 219594:AGAP3
uniprot id: A0A6J3CHW7
names: Similarity
messages: Belongs to the centaurin gamma-like family.

219594:KLHL22
gene id: 219594:KLHL22
uniprot id: A0A6J3E007
names: Subcellular Location Annotation
messages: Lysosome
messages: Nucleus
messages: centrosome
messages: cytosol
messages: spindle

219594:LOC116497747
gene id: 219594:LOC116497747
uniprot id: A0A6J3E826
names: Similarity
messages: Belongs to the 'GDXG' lipolytic enzyme family.

219594:DMRTB1
gene id: 219594:DMRTB1
uniprot id: A0A6J3DBB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DMRT family.
messages: Nucleus

219594:LOC116489074
gene id: 219594:LOC116489074
uniprot id: A0A6J3D0A5
uniprot id: A0A6J3D1G0
names: Similarity
messages: Belongs to the cytochrome P450 family.

219594:APC
gene id: 219594:APC
uniprot id: A0A6J3ECN6
uniprot id: A0A6J3EHI8
uniprot id: A0A6J3EHR4
names: Similarity
messages: Belongs to the adenomatous polyposis coli (APC) family.

219594:FOXO3
gene id: 219594:FOXO3
uniprot id: A0A6J3CWV6
names: Subcellular Location Annotation
messages: Nucleus

219594:MRPS18C
gene id: 219594:MRPS18C
uniprot id: A0A6J3CSX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Mitochondrion

219594:SNX6
gene id: 219594:SNX6
uniprot id: A0A6J3D1G1
uniprot id: A0A6J3D3Y5
names: Function
names: Similarity
messages: Belongs to the sorting nexin family.
messages: Involved in several stages of intracellular trafficking.

219594:LOC116488328
gene id: 219594:LOC116488328
uniprot id: A0A6J3CWN0
names: Similarity
messages: Belongs to the PRORSD1 family.

219594:BTBD10
gene id: 219594:BTBD10
uniprot id: A0A6J3CWZ6
uniprot id: A0A6J3CZ88
uniprot id: A0A6J3D2X7
names: Subcellular Location Annotation
messages: Cytoplasm

219594:ARL6IP4
gene id: 219594:ARL6IP4
uniprot id: A0A6J3DWN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ARL6IP4 family.
messages: Nucleus speckle
messages: nucleolus

219594:PHTF1
gene id: 219594:PHTF1
uniprot id: A0A6J3ED49
names: Subcellular Location Annotation
messages: Membrane

219594:DNAH10
gene id: 219594:DNAH10
uniprot id: A0A6J3E092
names: Similarity
messages: Belongs to the dynein heavy chain family.

219594:SPCS1
gene id: 219594:SPCS1
uniprot id: A0A6J3DFW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPCS1 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

219594:CHRNA1
gene id: 219594:CHRNA1
uniprot id: A0A6J3DAC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

219594:SPAM1
gene id: 219594:SPAM1
uniprot id: A0A6J3E919
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 56 family.
messages: Cell membrane
messages: Membrane

219594:MTIF2
gene id: 219594:MTIF2
uniprot id: A0A6J3CRD8
names: Function
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

219594:LCOR
gene id: 219594:LCOR
uniprot id: A0A6J3D5V5
names: Subcellular Location Annotation
messages: Nucleus

219594:NGFR
gene id: 219594:NGFR
uniprot id: A0A6J3E600
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:NPPC
gene id: 219594:NPPC
uniprot id: A0A6J3DJS3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the natriuretic peptide family.
messages: Secreted

219594:LOC116492441
gene id: 219594:LOC116492441
uniprot id: A0A6J3DHR8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.
messages: Heterodimer of an alpha and a beta subunit.
messages: Mitochondrion matrix
messages: The electron transfer flavoprotein serves as a specific electron acceptor for several dehydrogenases, including five acyl-CoA dehydrogenases, glutaryl-CoA and sarcosine dehydrogenase. It transfers the electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

219594:EPS8
gene id: 219594:EPS8
uniprot id: A0A6J3D721
uniprot id: A0A6J3D9S7
names: Similarity
messages: Belongs to the EPS8 family.

219594:PLSCR1
gene id: 219594:PLSCR1
uniprot id: A0A6J3DD34
uniprot id: A0A6J3DFS7
uniprot id: A0A6J3DH06
names: Function
names: Similarity
messages: Belongs to the phospholipid scramblase family.
messages: May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane.

219594:GRK7
gene id: 219594:GRK7
uniprot id: A0A6J3DH65
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.

219594:DLG3
gene id: 219594:DLG3
uniprot id: A0A6J3DN13
uniprot id: A0A6J3DPU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAGUK family.
messages: Membrane

219594:RRP1B
gene id: 219594:RRP1B
uniprot id: A0A6J3DH83
uniprot id: A0A6J3DMP8
names: Similarity
messages: Belongs to the RRP1 family.

219594:KHDRBS1
gene id: 219594:KHDRBS1
uniprot id: A0A6J3E871
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KHDRBS family.
messages: Cytoplasm

219594:MRPS5
gene id: 219594:MRPS5
uniprot id: A0A6J3CNT1
uniprot id: A0A6J3CQR6
names: Similarity
messages: Belongs to the universal ribosomal protein uS5 family.

219594:NDEL1
gene id: 219594:NDEL1
uniprot id: A0A6J3DXS0
uniprot id: A0A6J3E029
uniprot id: A0A6J3E205
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nudE family.
messages: centrosome
messages: spindle

219594:KCNH8
gene id: 219594:KCNH8
uniprot id: A0A6J3CM68
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: The potassium channel is probably composed of a homo- or heterotetrameric complex of pore-forming alpha subunits that can associate with modulating beta subunits.

219594:MSH3
gene id: 219594:MSH3
uniprot id: A0A6J3EJB3
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: Component of the post-replicative DNA mismatch repair system (MMR).

219594:MAP2K1
gene id: 219594:MAP2K1
uniprot id: A0A6J3DGM9
uniprot id: A0A6J3DKP4
names: Similarity
messages: Belongs to the protein kinase superfamily.

219594:CENPI
gene id: 219594:CENPI
uniprot id: A0A6J3DRA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CENP-I/CTF3 family.
messages: Nucleus
messages: centromere

219594:LOC116488542
gene id: 219594:LOC116488542
uniprot id: A0A6J3CSK4
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

219594:DPAGT1
gene id: 219594:DPAGT1
uniprot id: A0A6J3E2R4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family.
messages: Catalyzes the initial step of dolichol-linked oligosaccharide biosynthesis in N-linked protein glycosylation pathway: transfers GlcNAc-1-P from UDP-GlcNAc onto the carrier lipid dolichyl phosphate (P-dolichol), yielding GlcNAc-P-P-dolichol.
messages: Endoplasmic reticulum membrane
messages: Membrane

219594:LOC116495607
gene id: 219594:LOC116495607
uniprot id: A0A6J3DXU4
names: Subcellular Location Annotation
messages: Golgi apparatus membrane
messages: Membrane

219594:CNNM2
gene id: 219594:CNNM2
uniprot id: A0A6J3DC81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ACDP family.
messages: Membrane

219594:SNX13
gene id: 219594:SNX13
uniprot id: A0A6J3CD73
names: Similarity
messages: Belongs to the sorting nexin family.

219594:LOC116500389
gene id: 219594:LOC116500389
uniprot id: A0A6J3EH23
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alpha/beta interferon family.
messages: Has antiviral activities.
messages: Secreted

219594:EVX2
gene id: 219594:EVX2
uniprot id: A0A6J3D7Z9
names: Subcellular Location Annotation
messages: Nucleus

219594:LOC116499834
gene id: 219594:LOC116499834
uniprot id: A0A6J3EF77
names: Similarity
messages: Belongs to the intermediate filament family.

219594:IGFBP3
gene id: 219594:IGFBP3
uniprot id: A0A6J3CH70
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

219594:DGCR2
gene id: 219594:DGCR2
uniprot id: A0A6J3DYN1
uniprot id: A0A6J3DZQ8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:GPR182
gene id: 219594:GPR182
uniprot id: A0A6J3EHH0
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

219594:LOC116491970
gene id: 219594:LOC116491970
uniprot id: A0A6J3DFN1
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

219594:LOC116499740
gene id: 219594:LOC116499740
uniprot id: A0A6J3E9U3
names: Similarity
names: Subunit
messages: Belongs to the avian keratin family.
messages: The avian keratins (F-ker, S-ker, C-ker and B-ker) are a complex mixture of very similar polypeptides.

219594:MID2
gene id: 219594:MID2
uniprot id: A0A6J3DNK8
names: Subcellular Location Annotation
messages: cytoskeleton

219594:TFCP2
gene id: 219594:TFCP2
uniprot id: A0A6J3EF82
names: Subcellular Location Annotation
messages: Nucleus

219594:TMEM269
gene id: 219594:TMEM269
uniprot id: A0A6J3E5X8
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

219594:AGT
gene id: 219594:AGT
uniprot id: A0A6J3CW35
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the serpin family.
messages: Essential component of the renin-angiotensin system (RAS), a potent regulator of blood pressure, body fluid and electrolyte homeostasis.
messages: Secreted
messages: Stimulates aldosterone release.

219594:LOC116497401
gene id: 219594:LOC116497401
uniprot id: A0A6J3E5A7
names: Similarity
messages: Belongs to the 3-beta-HSD family.

219594:ZDHHC23
gene id: 219594:ZDHHC23
uniprot id: A0A6J3ENG6
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

219594:AQP9
gene id: 219594:AQP9
uniprot id: A0A6J3DJ22
uniprot id: A0A6J3DME8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Cell membrane
messages: Membrane

219594:CRYBA2
gene id: 219594:CRYBA2
uniprot id: A0A6J3D863
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

219594:CDC20
gene id: 219594:CDC20
uniprot id: A0A6J3DDJ6
names: Similarity
messages: Belongs to the WD repeat CDC20/Fizzy family.

219594:HSD17B2
gene id: 219594:HSD17B2
uniprot id: A0A6J3DNQ8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

219594:PHF10
gene id: 219594:PHF10
uniprot id: A0A6J3CM23
uniprot id: A0A6J3CN60
uniprot id: A0A6J3CQE0
uniprot id: A0A6J3CRG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SAYP family.
messages: Nucleus

219594:GKAP1
gene id: 219594:GKAP1
uniprot id: A0A6J3EDU6
names: Similarity
messages: Belongs to the GKAP1 family.

219594:PDX1
gene id: 219594:PDX1
uniprot id: A0A6J3EP98
names: Subcellular Location Annotation
messages: Nucleus

219594:LOC116496010
gene id: 219594:LOC116496010
uniprot id: A0A6J3DVF9
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

219594:UBE2G1
gene id: 219594:UBE2G1
uniprot id: A0A6J3E4I6
uniprot id: A0A6J3E5J2
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

219594:LOC116498657
gene id: 219594:LOC116498657
uniprot id: A0A6J3E6V8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:LOC116499343
gene id: 219594:LOC116499343
uniprot id: A0A6J3EF31
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:LOC116488499
gene id: 219594:LOC116488499
uniprot id: A0A6J3CUM1
names: Similarity
messages: Belongs to the cytochrome P450 family.

219594:LOC116492067
gene id: 219594:LOC116492067
uniprot id: A0A6J3DE19
names: Similarity
messages: Belongs to the amidase family.

219594:LOC116501988
gene id: 219594:LOC116501988
uniprot id: A0A6J3EJW4
names: Similarity
messages: Belongs to the PTEN phosphatase protein family.

219594:MCM3
gene id: 219594:MCM3
uniprot id: A0A6J3CXX0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.
messages: Belongs to the MCM family.
messages: Chromosome
messages: Component of the MCM2-7 complex.
messages: Nucleus

219594:FAM161A
gene id: 219594:FAM161A
uniprot id: A0A6J3CMA2
names: Similarity
messages: Belongs to the FAM161 family.

219594:HOXA13
gene id: 219594:HOXA13
uniprot id: A0A6J3CJ88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus

219594:JMJD1C
gene id: 219594:JMJD1C
uniprot id: A0A6J3D5F9
uniprot id: A0A6J3DAU5
names: Subcellular Location Annotation
messages: Nucleus

219594:TPRA1
gene id: 219594:TPRA1
uniprot id: A0A6J3DL46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0359 family.
messages: Membrane

219594:APPL2
gene id: 219594:APPL2
uniprot id: A0A6J3EQ44
uniprot id: A0A6J3EQ51
names: Subcellular Location Annotation
messages: Early endosome membrane
messages: Endosome membrane
messages: Nucleus
messages: phagosome
messages: ruffle

219594:SNAPC3
gene id: 219594:SNAPC3
uniprot id: A0A6J3EHY3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SNAPC3/SRD2 family.
messages: Nucleus
messages: Part of the SNAPc complex composed of 5 subunits: SNAPC1, SNAPC2, SNAPC3, SNAPC4 and SNAPC5. SNAPC3 interacts with SNAPC1.
messages: Part of the SNAPc complex required for the transcription of both RNA polymerase II and III small-nuclear RNA genes. Binds to the proximal sequence element (PSE), a non-TATA-box basal promoter element common to these 2 types of genes. Recruits TBP and BRF2 to the U6 snRNA TATA box.

219594:LOC116497748
gene id: 219594:LOC116497748
uniprot id: A0A6J3E381
names: Similarity
messages: Belongs to the 'GDXG' lipolytic enzyme family.

219594:TLX2
gene id: 219594:TLX2
uniprot id: A0A6J3D1W6
names: Subcellular Location Annotation
messages: Nucleus

219594:GLYCTK
gene id: 219594:GLYCTK
uniprot id: A0A6J3DFT6
uniprot id: A0A6J3DLE1
names: Similarity
messages: Belongs to the glycerate kinase type-2 family.

219594:CSRNP3
gene id: 219594:CSRNP3
uniprot id: A0A6J3D2M1
uniprot id: A0A6J3D530
uniprot id: A0A6J3D5F7
uniprot id: A0A6J3D8I1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AXUD1 family.
messages: Nucleus

219594:PEAR1
gene id: 219594:PEAR1
uniprot id: A0A6J3EAH8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:FOXA2
gene id: 219594:FOXA2
uniprot id: A0A6J3CXB6
names: Subcellular Location Annotation
messages: Nucleus

219594:GDF11
gene id: 219594:GDF11
uniprot id: A0A6J3EF99
names: Similarity
messages: Belongs to the TGF-beta family.

219594:GPRC6A
gene id: 219594:GPRC6A
uniprot id: A0A6J3CQG2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

219594:DOCK2
gene id: 219594:DOCK2
uniprot id: A0A6J3DTR8
names: Similarity
messages: Belongs to the DOCK family.

219594:FZD8
gene id: 219594:FZD8
uniprot id: A0A6J3CKZ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor Fz/Smo family.
messages: Membrane

219594:RAP2A
gene id: 219594:RAP2A
uniprot id: A0A6J3D3X2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Ras family.
messages: Endosome membrane
messages: Recycling endosome membrane

219594:ACSS1
gene id: 219594:ACSS1
uniprot id: A0A6J3CMD7
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

219594:SLC25A48
gene id: 219594:SLC25A48
uniprot id: A0A6J3DSW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

219594:ADD3
gene id: 219594:ADD3
uniprot id: A0A6J3D8Q9
uniprot id: A0A6J3D8R5
names: Similarity
messages: Belongs to the aldolase class II family. Adducin subfamily.

219594:SLC7A11
gene id: 219594:SLC7A11
uniprot id: A0A6J3D1E3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. L-type amino acid transporter (LAT) (TC 2.A.3.8) family.
messages: Membrane

219594:LOC116501470
gene id: 219594:LOC116501470
uniprot id: A0A6J3EIB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:LOC116487726
gene id: 219594:LOC116487726
uniprot id: A0A6J3CNZ5
uniprot id: A0A6J3CQX7
uniprot id: A0A6J3CV19
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Generally pentameric. There are five types of GABA(A) receptor chains: alpha, beta, gamma, delta, and rho. Interacts with SQSTM1.
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

219594:LOC116489800
gene id: 219594:LOC116489800
uniprot id: A0A6J3D1Q1
names: Similarity
messages: Belongs to the HEBP family.

219594:HMGCR
gene id: 219594:HMGCR
uniprot id: A0A6J3EC92
uniprot id: A0A6J3EHB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HMG-CoA reductase family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Peroxisome membrane

219594:TAF4B
gene id: 219594:TAF4B
uniprot id: A0A6J3CF25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF4 family.
messages: Nucleus

219594:RPS2
gene id: 219594:RPS2
uniprot id: A0A6J3DWZ5
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel. Plays a role in the assembly and function of the 40S ribosomal subunit. Mutations in this protein affects the control of translational fidelity. Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly.

219594:NDRG1
gene id: 219594:NDRG1
uniprot id: A0A6J3CF71
names: Similarity
messages: Belongs to the NDRG family.

219594:COPS5
gene id: 219594:COPS5
uniprot id: A0A6J3CQ54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M67A family. CSN5 subfamily.
messages: synaptic vesicle

219594:SMARCA5
gene id: 219594:SMARCA5
uniprot id: A0A6J3CVJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF2/RAD54 helicase family. ISWI subfamily.
messages: Nucleus

219594:FAM174B
gene id: 219594:FAM174B
uniprot id: A0A6J3DGK8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM174 family.
messages: Membrane

219594:DLK2
gene id: 219594:DLK2
uniprot id: A0A6J3CQY1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:TPMT
gene id: 219594:TPMT
uniprot id: A0A6J3CD38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TPMT family.
messages: Cytoplasm

219594:WNT6
gene id: 219594:WNT6
uniprot id: A0A6J3DA28
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

219594:VPS35L
gene id: 219594:VPS35L
uniprot id: A0A6J3DR85
uniprot id: A0A6J3DU60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS35L family.
messages: Endosome

219594:LOC116497573
gene id: 219594:LOC116497573
uniprot id: A0A6J3E126
uniprot id: A0A6J3E629
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class 2 subfamily.
messages: Cytoplasm

219594:VRK1
gene id: 219594:VRK1
uniprot id: A0A6J3D340
names: Similarity
messages: Belongs to the protein kinase superfamily.

219594:BMP3
gene id: 219594:BMP3
uniprot id: A0A6J3CXN8
names: Similarity
messages: Belongs to the TGF-beta family.

219594:LOC116487209
gene id: 219594:LOC116487209
uniprot id: A0A6J3CL98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta-catenin family.
messages: Belongs to the eutherian X-chromosome-specific Armcx family.
messages: Membrane
messages: Vacuole membrane

219594:TPT1
gene id: 219594:TPT1
uniprot id: A0A6J3EQH4
names: Similarity
messages: Belongs to the TCTP family.

219594:PDE1C
gene id: 219594:PDE1C
uniprot id: A0A6J3CFW4
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family. PDE1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

219594:SNCB
gene id: 219594:SNCB
uniprot id: A0A6J3DS07
names: Similarity
messages: Belongs to the synuclein family.

219594:LOC116500129
gene id: 219594:LOC116500129
uniprot id: A0A6J3ECI7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:LOC116499533
gene id: 219594:LOC116499533
uniprot id: A0A6J3EFT3
names: Similarity
names: Subunit
messages: Belongs to the avian keratin family.
messages: The avian keratins (F-ker, S-ker, C-ker and B-ker) are a complex mixture of very similar polypeptides.

219594:LOC116488538
gene id: 219594:LOC116488538
uniprot id: A0A6J3CXN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine alpha (chemokine CxC) family.
messages: Secreted

219594:TDP1
gene id: 219594:TDP1
uniprot id: A0A6J3D100
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tyrosyl-DNA phosphodiesterase family.
messages: Nucleus

219594:SRM
gene id: 219594:SRM
uniprot id: A0A6J3E5U6
names: Similarity
messages: Belongs to the spermidine/spermine synthase family.

219594:PDGFRB
gene id: 219594:PDGFRB
uniprot id: A0A6J3DMF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
messages: Membrane

219594:TMSB4X
gene id: 219594:TMSB4X
uniprot id: A0A6J3ENM2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thymosin beta family.
messages: Plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization.
messages: cytoskeleton

219594:LOC116491267
gene id: 219594:LOC116491267
uniprot id: A0A6J3DBZ1
names: Similarity
messages: Belongs to the neutral ceramidase family.

219594:LOC116486628
gene id: 219594:LOC116486628
uniprot id: A0A6J3CKB0
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

219594:UBIAD1
gene id: 219594:UBIAD1
uniprot id: A0A6J3E528
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family.
messages: Membrane

219594:HOMER3
gene id: 219594:HOMER3
uniprot id: A0A6J3EBZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Homer family.
messages: Cytoplasm
messages: Postsynaptic density
messages: Synapse

219594:LOC116492645
gene id: 219594:LOC116492645
uniprot id: A0A6J3DJ75
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

219594:ADORA3
gene id: 219594:ADORA3
uniprot id: A0A6J3EB17
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase.

219594:RAB3A
gene id: 219594:RAB3A
uniprot id: A0A6J3ECQ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Cell membrane
messages: Protein transport. Probably involved in vesicular traffic.

219594:LOC116490633
gene id: 219594:LOC116490633
uniprot id: A0A6J3D6J8
names: Subcellular Location Annotation
messages: Nucleus

219594:SLC39A3
gene id: 219594:SLC39A3
uniprot id: A0A6J3EBS7
names: Subcellular Location Annotation
messages: Membrane

219594:CHRNB3
gene id: 219594:CHRNB3
uniprot id: A0A6J3EHT9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

219594:ORC6
gene id: 219594:ORC6
uniprot id: A0A6J3DJ10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ORC6 family.
messages: Nucleus

219594:TMEM132B
gene id: 219594:TMEM132B
uniprot id: A0A6J3DZB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM132 family.
messages: Membrane

219594:HYAL3
gene id: 219594:HYAL3
uniprot id: A0A6J3DLA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 56 family.
messages: Cell membrane
messages: Early endosome
messages: Endoplasmic reticulum
messages: Endosome
messages: Membrane
messages: acrosome

219594:CAVIN1
gene id: 219594:CAVIN1
uniprot id: A0A6J3E4V4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAVIN family.
messages: caveola

219594:LOC116491642
gene id: 219594:LOC116491642
uniprot id: A0A6J3DB09
uniprot id: A0A6J3DBV5
names: Similarity
messages: Belongs to the cytochrome P450 family.

219594:WASF3
gene id: 219594:WASF3
uniprot id: A0A6J3DP20
uniprot id: A0A6J3DQ93
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SCAR/WAVE family.
messages: Binds actin and the Arp2/3 complex.
messages: Downstream effector molecule involved in the transmission of signals from tyrosine kinase receptors and small GTPases to the actin cytoskeleton. Promotes formation of actin filaments. Part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex.
messages: cytoskeleton

219594:PTK7
gene id: 219594:PTK7
uniprot id: A0A6J3CSK2
names: Subcellular Location Annotation
messages: Membrane

219594:KIT
gene id: 219594:KIT
uniprot id: A0A6J3CZJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
messages: Membrane

219594:ARHGDIA
gene id: 219594:ARHGDIA
uniprot id: A0A6J3DW48
names: Similarity
messages: Belongs to the Rho GDI family.

219594:LOC116487147
gene id: 219594:LOC116487147
uniprot id: A0A6J3CL08
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

219594:LOC116498587
gene id: 219594:LOC116498587
uniprot id: A0A6J3EBQ9
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Alax-L subfamily.

219594:AGTR2
gene id: 219594:AGTR2
uniprot id: A0A6J3DK90
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Interacts with MTUS1.
messages: Membrane

219594:TNK2
gene id: 219594:TNK2
uniprot id: A0A6J3DFJ7
uniprot id: A0A6J3DGS3
uniprot id: A0A6J3DID9
uniprot id: A0A6J3DIZ2
names: Subcellular Location Annotation
messages: Membrane
messages: Nucleus

219594:UBAC2
gene id: 219594:UBAC2
uniprot id: A0A6J3CIH1
uniprot id: A0A6J3CLG3
names: Subcellular Location Annotation
messages: Membrane

219594:APPL1
gene id: 219594:APPL1
uniprot id: A0A6J3DKW4
names: Subcellular Location Annotation
messages: Early endosome membrane
messages: Endosome membrane
messages: Nucleus
messages: phagosome
messages: ruffle

219594:BTD
gene id: 219594:BTD
uniprot id: A0A6J3CJF5
uniprot id: A0A6J3CKW2
uniprot id: A0A6J3CM26
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. BTD/VNN family.

219594:CD109
gene id: 219594:CD109
uniprot id: A0A6J3CSY2
uniprot id: A0A6J3CV88
names: Similarity
messages: Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family.

219594:CHRNA10
gene id: 219594:CHRNA10
uniprot id: A0A6J3EKL2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

219594:LOC116501948
gene id: 219594:LOC116501948
uniprot id: A0A6J3EQK2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H4 family.
messages: Chromosome
messages: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

219594:TYMS
gene id: 219594:TYMS
uniprot id: A0A6J3CF75
names: Similarity
messages: Belongs to the thymidylate synthase family.

219594:SUMF2
gene id: 219594:SUMF2
uniprot id: A0A6J3DZI5
uniprot id: A0A6J3E4M3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfatase-modifying factor family.
messages: Endoplasmic reticulum lumen

219594:LPAR4
gene id: 219594:LPAR4
uniprot id: A0A6J3DLX9
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

219594:SH3YL1
gene id: 219594:SH3YL1
uniprot id: A0A6J3CPK5
uniprot id: A0A6J3CQC2
names: Similarity
messages: Belongs to the SH3YL1 family.

219594:IDUA
gene id: 219594:IDUA
uniprot id: A0A6J3EEM3
uniprot id: A0A6J3EK26
names: Similarity
messages: Belongs to the glycosyl hydrolase 39 family.

219594:SVBP
gene id: 219594:SVBP
uniprot id: A0A6J3E6B6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SVBP family.
messages: Secreted
messages: cytoskeleton

219594:AARS2
gene id: 219594:AARS2
uniprot id: A0A6J3CQ86
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Alax-L subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Monomer. Interacts with ANKRD16; the interaction is direct.

219594:PDLIM1
gene id: 219594:PDLIM1
uniprot id: A0A6J3D816
names: Subcellular Location Annotation
messages: Z line

219594:TCTN3
gene id: 219594:TCTN3
uniprot id: A0A6J3DCS8
names: Similarity
names: Subunit
messages: Belongs to the tectonic family.
messages: Part of the tectonic-like complex (also named B9 complex).

219594:CILP
gene id: 219594:CILP
uniprot id: A0A6J3DIR6
names: Subcellular Location Annotation
messages: extracellular matrix

219594:LOC116494431
gene id: 219594:LOC116494431
uniprot id: A0A6J3DRI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:STAC
gene id: 219594:STAC
uniprot id: A0A6J3CE92
names: Subcellular Location Annotation
messages: sarcolemma

219594:PRKCE
gene id: 219594:PRKCE
uniprot id: A0A6J3CMT5
uniprot id: A0A6J3CR36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
messages: Cytoplasm

219594:PLIN1
gene id: 219594:PLIN1
uniprot id: A0A6J3DI32
names: Similarity
messages: Belongs to the perilipin family.

219594:LOC116498511
gene id: 219594:LOC116498511
uniprot id: A0A6J3E6C7
names: Similarity
names: Subunit
messages: Belongs to the avian keratin family.
messages: The avian keratins (F-ker, S-ker, C-ker and B-ker) are a complex mixture of very similar polypeptides.

219594:SDAD1
gene id: 219594:SDAD1
uniprot id: A0A6J3CW74
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SDA1 family.
messages: Required for 60S pre-ribosomal subunits export to the cytoplasm.
messages: nucleolus

219594:ZWILCH
gene id: 219594:ZWILCH
uniprot id: A0A6J3DI25
uniprot id: A0A6J3DNJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ZWILCH family.
messages: Component of the RZZ complex.
messages: Essential component of the mitotic checkpoint, which prevents cells from prematurely exiting mitosis. Required for the assembly of the dynein-dynactin and MAD1-MAD2 complexes onto kinetochores. Its function related to the spindle assembly machinery is proposed to depend on its association in the mitotic RZZ complex.
messages: kinetochore

219594:FGF3
gene id: 219594:FGF3
uniprot id: A0A6J3D460
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

219594:ZPBP2
gene id: 219594:ZPBP2
uniprot id: A0A6J3EAJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the zona pellucida-binding protein Sp38 family.
messages: Secreted

219594:DHRS7
gene id: 219594:DHRS7
uniprot id: A0A6J3D3S3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

219594:LOC116498972
gene id: 219594:LOC116498972
uniprot id: A0A6J3EDI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:NUDT19
gene id: 219594:NUDT19
uniprot id: A0A6J3DP53
names: Similarity
messages: Belongs to the Nudix hydrolase family.

219594:MMGT1
gene id: 219594:MMGT1
uniprot id: A0A6J3DRM6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane magnesium transporter (TC 1.A.67) family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Golgi apparatus membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the endoplasmic reticulum membrane protein complex (EMC) that enables the energy-independent insertion into endoplasmic reticulum membranes of newly synthesized membrane proteins. May be involved in Mg(2+) transport.

219594:ATP10A
gene id: 219594:ATP10A
uniprot id: A0A6J3DYN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

219594:ST14
gene id: 219594:ST14
uniprot id: A0A6J3E2G5
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

219594:SATB2
gene id: 219594:SATB2
uniprot id: A0A6J3D8B5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CUT homeobox family.
messages: Nucleus

219594:CASP6
gene id: 219594:CASP6
uniprot id: A0A6J3CXB4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase C14A family.
messages: Cytoplasm
messages: Heterotetramer that consists of two anti-parallel arranged heterodimers, each one formed by a 18 kDa (Caspase-6 subunit p18) and a 11 kDa (Caspase-6 subunit p11) subunit.
messages: Nucleus

219594:TMPRSS15
gene id: 219594:TMPRSS15
uniprot id: A0A6J3DQQ8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DMBT1 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

219594:LOC116489662
gene id: 219594:LOC116489662
uniprot id: A0A6J3CYC9
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

219594:SYNE2
gene id: 219594:SYNE2
uniprot id: A0A6J3CYG6
uniprot id: A0A6J3D0Y8
uniprot id: A0A6J3D3F8
names: Similarity
messages: Belongs to the nesprin family.

219594:HEATR1
gene id: 219594:HEATR1
uniprot id: A0A6J3CSM0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HEATR1/UTP10 family.
messages: Involved in nucleolar processing of pre-18S ribosomal RNA.
messages: nucleolus

219594:TM4SF4
gene id: 219594:TM4SF4
uniprot id: A0A6J3DI34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L6 tetraspanin family.
messages: Membrane

219594:LOC116499836
gene id: 219594:LOC116499836
uniprot id: A0A6J3EGX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glucagon family.
messages: Secreted

219594:ACER1
gene id: 219594:ACER1
uniprot id: A0A6J3E9L2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alkaline ceramidase family.
messages: Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid.
messages: Membrane

219594:TDRD3
gene id: 219594:TDRD3
uniprot id: A0A6J3D086
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus
messages: Scaffolding protein that specifically recognizes and binds dimethylarginine-containing proteins. In nucleus, acts as a coactivator: recognizes and binds asymmetric dimethylation on the core histone tails associated with transcriptional activation (H3R17me2a and H4R3me2a) and recruits proteins at these arginine-methylated loci. In cytoplasm, may play a role in the assembly and/or disassembly of mRNA stress granules and in the regulation of translation of target mRNAs by binding Arg/Gly-rich motifs (GAR) in dimethylarginine-containing proteins.

219594:NUP35
gene id: 219594:NUP35
uniprot id: A0A6J3D6D3
uniprot id: A0A6J3D930
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Nup35 family.
messages: Functions as a component of the nuclear pore complex (NPC).
messages: nuclear pore complex

219594:PCYT2
gene id: 219594:PCYT2
uniprot id: A0A6J3DW11
uniprot id: A0A6J3E105
names: Similarity
messages: Belongs to the cytidylyltransferase family.

219594:LOC116488885
gene id: 219594:LOC116488885
uniprot id: A0A6J3CX68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Toll-like receptor family.
messages: Membrane

219594:ERG
gene id: 219594:ERG
uniprot id: A0A6J3EKV1
uniprot id: A0A6J3EPT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

219594:F3
gene id: 219594:F3
uniprot id: A0A6J3DDH6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tissue factor family.
messages: Initiates blood coagulation by forming a complex with circulating factor VII or VIIa. The [TF:VIIa] complex activates factors IX or X by specific limited proteolysis. TF plays a role in normal hemostasis by initiating the cell-surface assembly and propagation of the coagulation protease cascade.
messages: Interacts with HSPE; the interaction, inhibited by heparin, promotes the generation of activated factor X and activates coagulation in the presence of activated factor VII.

219594:DUSP27
gene id: 219594:DUSP27
uniprot id: A0A6J3EIC8
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.

219594:PSMC3IP
gene id: 219594:PSMC3IP
uniprot id: A0A6J3E630
uniprot id: A0A6J3E922
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HOP2 family.
messages: Nucleus

219594:PRCP
gene id: 219594:PRCP
uniprot id: A0A6J3EI04
names: Similarity
messages: Belongs to the peptidase S28 family.

219594:DHH
gene id: 219594:DHH
uniprot id: A0A6J3EC30
uniprot id: A0A6J3EHE0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the hedgehog family.
messages: Cell membrane
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Membrane
messages: Multimer.
messages: The C-terminal part of the hedgehog protein precursor displays an autoproteolysis activity that results in the cleavage of the full-length protein into two parts (N-product and C-product). In addition, the C-terminal part displays a cholesterol transferase activity that results by the covalent attachment of a cholesterol moiety to the C-terminal of the newly generated N-product.
messages: The dually lipidated hedgehog protein N-product is a morphogen which is essential for a variety of patterning events during development.

219594:SLC16A14
gene id: 219594:SLC16A14
uniprot id: A0A6J3DGX6
uniprot id: A0A6J3DIJ1
names: Subcellular Location Annotation
messages: Membrane

219594:NMS
gene id: 219594:NMS
uniprot id: A0A6J3E4P3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NmU family.
messages: Secreted

219594:TMEM230
gene id: 219594:TMEM230
uniprot id: A0A6J3EDC2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM134/TMEM230 family.
messages: Early endosome
messages: Endosome
messages: Involved in trafficking and recycling of synaptic vesicles.
messages: Late endosome
messages: Membrane
messages: Recycling endosome
messages: Vesicle
messages: autophagosome
messages: synaptic vesicle
messages: trans-Golgi network

219594:LOC116496623
gene id: 219594:LOC116496623
uniprot id: A0A6J3E2L3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: High affinity receptor for urotensin-2 and urotensin-2B. The activity of this receptor is mediated by a G-protein that activate a phosphatidylinositol-calcium second messenger system.
messages: Membrane

219594:MRPL42
gene id: 219594:MRPL42
uniprot id: A0A6J3DKV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL42 family.
messages: Mitochondrion

219594:LPCAT1
gene id: 219594:LPCAT1
uniprot id: A0A6J3CHA4
uniprot id: A0A6J3CJ22
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

219594:SDHA
gene id: 219594:SDHA
uniprot id: A0A6J3CLP3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).
messages: Mitochondrion inner membrane

219594:GAD1
gene id: 219594:GAD1
uniprot id: A0A6J3D9L4
names: Similarity
names: Subunit
messages: Belongs to the group II decarboxylase family.
messages: Homodimer.

219594:LOC116488095
gene id: 219594:LOC116488095
uniprot id: A0A6J3CVG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Endoplasmic reticulum membrane

219594:EML4
gene id: 219594:EML4
uniprot id: A0A6J3CKH2
uniprot id: A0A6J3CM06
uniprot id: A0A6J3CN47
uniprot id: A0A6J3CRF6
names: Similarity
messages: Belongs to the WD repeat EMAP family.

219594:LOC116486731
gene id: 219594:LOC116486731
uniprot id: A0A6J3CKS4
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

219594:LOC116492742
gene id: 219594:LOC116492742
uniprot id: A0A6J3DHK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alkaline phosphatase family.
messages: Cell membrane
messages: Membrane

219594:MYLK4
gene id: 219594:MYLK4
uniprot id: A0A6J3CDB0
names: Similarity
messages: Belongs to the protein kinase superfamily.

219594:INTS2
gene id: 219594:INTS2
uniprot id: A0A6J3DZU2
names: Similarity
messages: Belongs to the Integrator subunit 2 family.

219594:PPARG
gene id: 219594:PPARG
uniprot id: A0A6J3DEV2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Cytoplasm
messages: Heterodimer with other nuclear receptors.
messages: Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. May play a role in the regulation of circadian rhythm.
messages: Nucleus

219594:DESI2
gene id: 219594:DESI2
uniprot id: A0A6J3CTZ1
names: Similarity
messages: Belongs to the DeSI family.

219594:CASR
gene id: 219594:CASR
uniprot id: A0A6J3EJB6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

219594:GDF7
gene id: 219594:GDF7
uniprot id: A0A6J3CRC9
names: Similarity
messages: Belongs to the TGF-beta family.

219594:LOC116500825
gene id: 219594:LOC116500825
uniprot id: A0A6J3EJA1
names: Similarity
messages: Belongs to the SERF family.

219594:LOC116493247
gene id: 219594:LOC116493247
uniprot id: A0A6J3DLX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dynein light chain family.
messages: cytoskeleton

219594:KIF18A
gene id: 219594:KIF18A
uniprot id: A0A6J3D288
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

219594:RNF111
gene id: 219594:RNF111
uniprot id: A0A6J3DGU3
uniprot id: A0A6J3DKW6
uniprot id: A0A6J3DMC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Arkadia family.
messages: PML body

219594:LOC116496845
gene id: 219594:LOC116496845
uniprot id: A0A6J3DXL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:CYRIB
gene id: 219594:CYRIB
uniprot id: A0A6J3CE25
uniprot id: A0A6J3CIL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CYRI family.
messages: Membrane

219594:HTRA2
gene id: 219594:HTRA2
uniprot id: A0A6J3CYZ5
names: Similarity
messages: Belongs to the peptidase S1C family.

219594:TMEM200B
gene id: 219594:TMEM200B
uniprot id: A0A6J3E3H3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM200 family.
messages: Membrane

219594:SPTBN1
gene id: 219594:SPTBN1
uniprot id: A0A6J3CWS2
uniprot id: A0A6J3CXV9
names: Similarity
messages: Belongs to the spectrin family.

219594:GLDC
gene id: 219594:GLDC
uniprot id: A0A6J3EFR3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GcvP family.
messages: Mitochondrion
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

219594:FBXL5
gene id: 219594:FBXL5
uniprot id: A0A6J3CSF1
uniprot id: A0A6J3CUR1
names: Subcellular Location Annotation
messages: perinuclear region

219594:C8A
gene id: 219594:C8A
uniprot id: A0A6J3DDK7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complement C6/C7/C8/C9 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Secreted

219594:TDP2
gene id: 219594:TDP2
uniprot id: A0A6J3CJ34
names: Subcellular Location Annotation
messages: PML body

219594:TSPAN1
gene id: 219594:TSPAN1
uniprot id: A0A6J3DE22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

219594:SLC5A3
gene id: 219594:SLC5A3
uniprot id: A0A6J3CHB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

219594:ITGA4
gene id: 219594:ITGA4
uniprot id: A0A6J3D6J4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

219594:YWHAG
gene id: 219594:YWHAG
uniprot id: A0A6J3E3W6
names: Similarity
messages: Belongs to the 14-3-3 family.

219594:CEP70
gene id: 219594:CEP70
uniprot id: A0A6J3D555
uniprot id: A0A6J3DB23
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Directly interacts with tubulin-gamma; this interaction determines centrosomal localization.
messages: Plays a role in the organization of both preexisting and nascent microtubules in interphase cells. During mitosis, required for the organization and orientation of the mitotic spindle.
messages: centrosome

219594:RIPPLY3
gene id: 219594:RIPPLY3
uniprot id: A0A6J3CJM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ripply family.
messages: Nucleus

219594:FAM155A
gene id: 219594:FAM155A
uniprot id: A0A6J3D4B9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NALF family.
messages: Membrane

219594:ERBB4
gene id: 219594:ERBB4
uniprot id: A0A6J3D904
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. EGF receptor subfamily.
messages: Membrane

219594:TPPP3
gene id: 219594:TPPP3
uniprot id: A0A6J3DLY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TPPP family.
messages: cytoskeleton

219594:ZDHHC13
gene id: 219594:ZDHHC13
uniprot id: A0A6J3CZ66
uniprot id: A0A6J3D1R0
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family. AKR/ZDHHC17 subfamily.
messages: Cytoplasmic vesicle membrane
messages: Golgi apparatus membrane
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

219594:ANTKMT
gene id: 219594:ANTKMT
uniprot id: A0A6J3DUL5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ANT/ATPSC lysine N-methyltransferase family.
messages: Mitochondrion membrane

219594:GNAS
gene id: 219594:GNAS
uniprot id: A0A6J3DRE3
uniprot id: A0A6J3DVS0
names: Similarity
messages: Belongs to the G-alpha family. G(s) subfamily.

219594:SH3GL1
gene id: 219594:SH3GL1
uniprot id: A0A6J3E7S6
uniprot id: A0A6J3ECW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endophilin family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Membrane

219594:LOC116486268
gene id: 219594:LOC116486268
uniprot id: A0A6J3CLF8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G protein gamma family.
messages: Cell membrane
messages: G proteins are composed of 3 units; alpha, beta and gamma.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

219594:MRS2
gene id: 219594:MRS2
uniprot id: A0A6J3CGQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mitochondrion inner membrane

219594:LOC116500148
gene id: 219594:LOC116500148
uniprot id: A0A6J3EHW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:MED12
gene id: 219594:MED12
uniprot id: A0A6J3DNI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mediator complex subunit 12 family.
messages: Nucleus

219594:DAP3
gene id: 219594:DAP3
uniprot id: A0A6J3EEZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mS29 family.
messages: Mitochondrion

219594:CASKIN2
gene id: 219594:CASKIN2
uniprot id: A0A6J3DWB1
names: Subcellular Location Annotation
messages: Cytoplasm

219594:SPC25
gene id: 219594:SPC25
uniprot id: A0A6J3DAK7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.
messages: Belongs to the SPC25 family.
messages: Component of the NDC80 complex.
messages: Nucleus
messages: kinetochore

219594:TTYH2
gene id: 219594:TTYH2
uniprot id: A0A6J3DWV3
uniprot id: A0A6J3E119
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tweety family.
messages: Cell membrane
messages: Membrane
messages: Probable chloride channel.

219594:LOC116494025
gene id: 219594:LOC116494025
uniprot id: A0A6J3DLZ9
names: Similarity
messages: Belongs to the arylamine N-acetyltransferase family.

219594:ATP13A4
gene id: 219594:ATP13A4
uniprot id: A0A6J3DCF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily.
messages: Membrane

219594:LOC116494178
gene id: 219594:LOC116494178
uniprot id: A0A6J3DR73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COX17 family.
messages: Mitochondrion intermembrane space

219594:NDUFS1
gene id: 219594:NDUFS1
uniprot id: A0A6J3D7J9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I 75 kDa subunit family.
messages: Mitochondrion inner membrane

219594:IGF1
gene id: 219594:IGF1
uniprot id: A0A6J3DNQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the insulin family.
messages: Secreted

219594:AKT3
gene id: 219594:AKT3
uniprot id: A0A6J3CSS2
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. RAC subfamily.

219594:NADK2
gene id: 219594:NADK2
uniprot id: A0A6J3EE04
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NAD kinase family.
messages: Homodimer.
messages: Mitochondrial NAD(+) kinase that phosphorylates NAD(+) to yield NADP(+). Can use both ATP or inorganic polyphosphate as the phosphoryl donor.
messages: Mitochondrion

219594:SGSM2
gene id: 219594:SGSM2
uniprot id: A0A6J3DZ09
uniprot id: A0A6J3E0M0
uniprot id: A0A6J3E0M5
uniprot id: A0A6J3E392
uniprot id: A0A6J3E397
uniprot id: A0A6J3E429
uniprot id: A0A6J3E542
names: Similarity
messages: Belongs to the RUTBC family.

219594:SLC6A9
gene id: 219594:SLC6A9
uniprot id: A0A6J3DAT1
uniprot id: A0A6J3DDE5
uniprot id: A0A6J3DGG0
uniprot id: A0A6J3DGL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A9 subfamily.
messages: Cell membrane
messages: Membrane

219594:B4GALT5
gene id: 219594:B4GALT5
uniprot id: A0A6J3DWW9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 7 family.
messages: Golgi apparatus membrane
messages: Membrane
messages: Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids.

219594:CRCP
gene id: 219594:CRCP
uniprot id: A0A6J3E504
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic RPC9 RNA polymerase subunit family.
messages: Nucleus

219594:LOC116497121
gene id: 219594:LOC116497121
uniprot id: A0A6J3E516
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

219594:AZIN1
gene id: 219594:AZIN1
uniprot id: A0A6J3CHC9
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

219594:SLITRK3
gene id: 219594:SLITRK3
uniprot id: A0A6J3DDZ8
names: Similarity
messages: Belongs to the SLITRK family.

219594:CLTB
gene id: 219594:CLTB
uniprot id: A0A6J3DT56
uniprot id: A0A6J3DU52
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the clathrin light chain family.
messages: Clathrin is the major protein of the polyhedral coat of coated pits and vesicles.
messages: Cytoplasmic vesicle membrane
messages: coated pit

219594:CTSD
gene id: 219594:CTSD
uniprot id: A0A6J3D370
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A1 family.
messages: Lysosome

219594:CAPN3
gene id: 219594:CAPN3
uniprot id: A0A6J3CY50
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase C2 family.
messages: Calcium-regulated non-lysosomal thiol-protease.
messages: Cytoplasm
messages: Homodimer.
messages: nucleolus

219594:FAP
gene id: 219594:FAP
uniprot id: A0A6J3DA49
names: Subcellular Location Annotation
messages: Cell membrane
messages: invadopodium membrane
messages: lamellipodium membrane

219594:ADAM12
gene id: 219594:ADAM12
uniprot id: A0A6J3DBR8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:ARAP2
gene id: 219594:ARAP2
uniprot id: A0A6J3CZ28
names: Subcellular Location Annotation
messages: Cytoplasm

219594:LOC116495434
gene id: 219594:LOC116495434
uniprot id: A0A6J3DV16
names: Function
names: Similarity
messages: Belongs to the parvalbumin family.
messages: In muscle, parvalbumin is thought to be involved in relaxation after contraction. It binds two calcium ions.

219594:HACD4
gene id: 219594:HACD4
uniprot id: A0A6J3EKK2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the very long-chain fatty acids dehydratase HACD family.
messages: Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

219594:AGMAT
gene id: 219594:AGMAT
uniprot id: A0A6J3E6T6
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.

219594:BCO1
gene id: 219594:BCO1
uniprot id: A0A6J3DIX4
uniprot id: A0A6J3DLF0
names: Similarity
messages: Belongs to the carotenoid oxygenase family.

219594:SEMA6B
gene id: 219594:SEMA6B
uniprot id: A0A6J3EC31
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:LAMC1
gene id: 219594:LAMC1
uniprot id: A0A6J3DAC3
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: basement membrane

219594:SNRPF
gene id: 219594:SNRPF
uniprot id: A0A6J3DTI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP Sm proteins family. SmF/LSm6 subfamily.
messages: Nucleus

219594:ALDH6A1
gene id: 219594:ALDH6A1
uniprot id: A0A6J3D3S7
names: Function
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.
messages: Plays a role in valine and pyrimidine metabolism. Binds fatty acyl-CoA.

219594:SIM1
gene id: 219594:SIM1
uniprot id: A0A6J3CSV6
names: Subcellular Location Annotation
messages: Nucleus

219594:OGFOD1
gene id: 219594:OGFOD1
uniprot id: A0A6J3DM97
names: Similarity
messages: Belongs to the TPA1 family.

219594:ARTN
gene id: 219594:ARTN
uniprot id: A0A6J3D8Q6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TGF-beta family. GDNF subfamily.
messages: Secreted

219594:PIAS1
gene id: 219594:PIAS1
uniprot id: A0A6J3DMH7
names: Similarity
messages: Belongs to the PIAS family.

219594:PGP
gene id: 219594:PGP
uniprot id: A0A6J3DQ76
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

219594:COPS2
gene id: 219594:COPS2
uniprot id: A0A6J3DM32
uniprot id: A0A6J3DMJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSN2 family.
messages: Cytoplasm
messages: Nucleus

219594:EGFR
gene id: 219594:EGFR
uniprot id: A0A6J3CKZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. EGF receptor subfamily.
messages: Membrane

219594:MTHFD1L
gene id: 219594:MTHFD1L
uniprot id: A0A6J3CPM0
names: Similarity
names: Subunit
messages: Homodimer.
messages: In the C-terminal section; belongs to the formate--tetrahydrofolate ligase family.
messages: In the N-terminal section; belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.

219594:MYO19
gene id: 219594:MYO19
uniprot id: A0A6J3DZ94
uniprot id: A0A6J3E0U6
uniprot id: A0A6J3E3I9
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

219594:LOC116489875
gene id: 219594:LOC116489875
uniprot id: A0A6J3D4I5
uniprot id: A0A6J3D5I4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M28 family. M28B subfamily.
messages: Cell membrane
messages: Membrane

219594:EXTL1
gene id: 219594:EXTL1
uniprot id: A0A6J3E873
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 47 family.
messages: Endoplasmic reticulum membrane

219594:USP28
gene id: 219594:USP28
uniprot id: A0A6J3E6G0
names: Similarity
messages: Belongs to the peptidase C19 family.

219594:PDE6G
gene id: 219594:PDE6G
uniprot id: A0A6J3DYG3
names: Function
names: Similarity
messages: Belongs to the rod/cone cGMP-PDE gamma subunit family.
messages: Participates in processes of transmission and amplification of the visual signal. cGMP-PDEs are the effector molecules in G-protein-mediated phototransduction in vertebrate rods and cones.

219594:LOC116498424
gene id: 219594:LOC116498424
uniprot id: A0A6J3E615
uniprot id: A0A6J3E902
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane

219594:TMEM115
gene id: 219594:TMEM115
uniprot id: A0A6J3DLS1
names: Subcellular Location Annotation
messages: Membrane

219594:F8
gene id: 219594:F8
uniprot id: A0A6J3DRS1
names: Similarity
messages: Belongs to the multicopper oxidase family.

219594:ACE
gene id: 219594:ACE
uniprot id: A0A6J3EBC1
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M2 family.
messages: Binds 2 Zn(2+) ions per subunit.

219594:LOC116500726
gene id: 219594:LOC116500726
uniprot id: A0A6J3EIR5
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class 1 subfamily.

219594:TTC38
gene id: 219594:TTC38
uniprot id: A0A6J3CQK8
names: Similarity
messages: Belongs to the TTC38 family.

219594:PGGT1B
gene id: 219594:PGGT1B
uniprot id: A0A6J3EF15
names: Similarity
messages: Belongs to the protein prenyltransferase subunit beta family.

219594:MTF2
gene id: 219594:MTF2
uniprot id: A0A6J3DCZ1
names: Subcellular Location Annotation
messages: Nucleus

219594:MASP1
gene id: 219594:MASP1
uniprot id: A0A6J3DGC0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:VIL1
gene id: 219594:VIL1
uniprot id: A0A6J3DA85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the villin/gelsolin family.
messages: filopodium tip
messages: lamellipodium
messages: microvillus
messages: ruffle

219594:LOC116500140
gene id: 219594:LOC116500140
uniprot id: A0A6J3EFY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:MIGA1
gene id: 219594:MIGA1
uniprot id: A0A6J3DC33
names: Similarity
messages: Belongs to the mitoguardin family.

219594:APOD
gene id: 219594:APOD
uniprot id: A0A6J3DH10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calycin superfamily. Lipocalin family.
messages: Secreted

219594:ADGRA1
gene id: 219594:ADGRA1
uniprot id: A0A6J3D601
uniprot id: A0A6J3D8P7
uniprot id: A0A6J3DBE4
uniprot id: A0A6J3DBW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily.
messages: Membrane

219594:MAPK1IP1L
gene id: 219594:MAPK1IP1L
uniprot id: A0A6J3D5U2
names: Similarity
messages: Belongs to the MISS family.

219594:CCN4
gene id: 219594:CCN4
uniprot id: A0A6J3CKT6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCN family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

219594:TICAM1
gene id: 219594:TICAM1
uniprot id: A0A6J3EBL7
names: Domain
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Homodimer. Found in a multi-helicase-TICAM1 complex at least composed of DHX36, DDX1, DDX21 and TICAM1.
messages: Involved in innate immunity against invading pathogens. Adapter used by TLR3, TLR4 (through TICAM2) and TLR5 to mediate NF-kappa-B and interferon-regulatory factor (IRF) activation, and to induce apoptosis. Ligand binding to these receptors results in TRIF recruitment through its TIR domain. Distinct protein-interaction motifs allow recruitment of the effector proteins TBK1, TRAF6 and RIPK1, which in turn, lead to the activation of transcription factors IRF3 and IRF7, NF-kappa-B and FADD respectively. Phosphorylation by TBK1 on the pLxIS motif leads to recruitment and subsequent activation of the transcription factor IRF3 to induce expression of type I interferon and exert a potent immunity against invading pathogens. Component of a multi-helicase-TICAM1 complex that acts as a cytoplasmic sensor of viral double-stranded RNA (dsRNA) and plays a role in the activation of a cascade of antiviral responses including the induction of pro-inflammatory cytokines.
messages: Mitochondrion
messages: The N-terminal region is essential for activation of the IFNB promoter activity.
messages: autophagosome
messages: cytosol

219594:AP3S1
gene id: 219594:AP3S1
uniprot id: A0A6J3EDV9
uniprot id: A0A6J3EFA8
uniprot id: A0A6J3EIQ7
uniprot id: A0A6J3EKN1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adaptor complexes small subunit family.
messages: Cytoplasmic vesicle membrane
messages: Membrane
messages: Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals.

219594:GPM6A
gene id: 219594:GPM6A
uniprot id: A0A6J3CYE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the myelin proteolipid protein family.
messages: Membrane

219594:S100A1
gene id: 219594:S100A1
uniprot id: A0A6J3E9W5
names: Similarity
messages: Belongs to the S-100 family.

219594:LOC116501767
gene id: 219594:LOC116501767
uniprot id: A0A6J3EHN6
uniprot id: A0A6J3EMX3
names: Similarity
messages: Belongs to the peptidase M14 family.

219594:NR4A2
gene id: 219594:NR4A2
uniprot id: A0A6J3D523
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Cytoplasm
messages: Nucleus

219594:CELF5
gene id: 219594:CELF5
uniprot id: A0A6J3E7H0
uniprot id: A0A6J3EC37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CELF/BRUNOL family.
messages: Cytoplasm
messages: Nucleus

219594:HIF1A
gene id: 219594:HIF1A
uniprot id: A0A6J3D7D9
names: Subcellular Location Annotation
messages: Cytoplasm

219594:KCNJ11
gene id: 219594:KCNJ11
uniprot id: A0A6J3D741
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family. KCNJ11 subfamily.
messages: Membrane

219594:SBNO2
gene id: 219594:SBNO2
uniprot id: A0A6J3E7J6
uniprot id: A0A6J3E927
uniprot id: A0A6J3EC64
names: Similarity
messages: Belongs to the SBNO family.

219594:PLCB1
gene id: 219594:PLCB1
uniprot id: A0A6J3CN37
uniprot id: A0A6J3CU59
names: Function
messages: The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.

219594:RPAIN
gene id: 219594:RPAIN
uniprot id: A0A6J3DZT7
names: Subcellular Location Annotation
messages: Nucleus

219594:FUNDC2
gene id: 219594:FUNDC2
uniprot id: A0A6J3DKY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FUN14 family.
messages: Mitochondrion outer membrane

219594:SCNN1A
gene id: 219594:SCNN1A
uniprot id: A0A6J3EN76
names: Subcellular Location Annotation
messages: Membrane

219594:RPS15A
gene id: 219594:RPS15A
uniprot id: A0A6J3DQW1
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: Component of the 40S ribosomal subunit.

219594:ADRA2A
gene id: 219594:ADRA2A
uniprot id: A0A6J3DAY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:AARS1
gene id: 219594:AARS1
uniprot id: A0A6J3DPF9
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Alax-L subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Monomer. Interacts with ANKRD16; the interaction is direct.

219594:GBA2
gene id: 219594:GBA2
uniprot id: A0A6J3EDY3
names: Function
names: Similarity
messages: Belongs to the non-lysosomal glucosylceramidase family.
messages: Non-lysosomal glucosylceramidase that catalyzes the hydrolysis of glucosylceramide (GlcCer) to free glucose and ceramide.

219594:ANXA6
gene id: 219594:ANXA6
uniprot id: A0A6J3DMU8
uniprot id: A0A6J3DQ65
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: A pair of annexin repeats may form one binding site for calcium and phospholipid.
messages: Belongs to the annexin family.
messages: May associate with CD21. May regulate the release of Ca(2+) from intracellular stores.
messages: Melanosome

219594:HCFC2
gene id: 219594:HCFC2
uniprot id: A0A6J3CTH9
names: Subcellular Location Annotation
messages: Nucleus

219594:IGFBP5
gene id: 219594:IGFBP5
uniprot id: A0A6J3DB59
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

219594:SMG1
gene id: 219594:SMG1
uniprot id: A0A6J3DNX0
uniprot id: A0A6J3DU53
uniprot id: A0A6J3DV03
names: Similarity
messages: Belongs to the PI3/PI4-kinase family.

219594:CDS1
gene id: 219594:CDS1
uniprot id: A0A6J3CZH5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Catalyzes the conversion of phosphatidic acid (PA) to CDP-diacylglycerol (CDP-DAG), an essential intermediate in the synthesis of phosphatidylglycerol, cardiolipin and phosphatidylinositol.
messages: Membrane

219594:SKP1
gene id: 219594:SKP1
uniprot id: A0A6J3DPX4
names: Function
names: Similarity
messages: Belongs to the SKP1 family.
messages: Essential component of the SCF (SKP1-CUL1-F-box protein) ubiquitin ligase complex, which mediates the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription. In the SCF complex, serves as an adapter that links the F-box protein to CUL1.

219594:HGF
gene id: 219594:HGF
uniprot id: A0A6J3DZ04
uniprot id: A0A6J3DZ33
uniprot id: A0A6J3E3A2
uniprot id: A0A6J3E3B4
uniprot id: A0A6J3E527
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S1 family. Plasminogen subfamily.
messages: Dimer of an alpha chain and a beta chain linked by a disulfide bond. Interacts with SRPX2; the interaction increases HGF mitogenic activity.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization.

219594:PACC1
gene id: 219594:PACC1
uniprot id: A0A6J3CNI4
uniprot id: A0A6J3CQR3
uniprot id: A0A6J3CRU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the proton-activated chloride channel family.
messages: Cell membrane
messages: Membrane

219594:NDUFB9
gene id: 219594:NDUFB9
uniprot id: A0A6J3CCX6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed to be not involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I LYR family.
messages: Mammalian complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

219594:LOC116491356
gene id: 219594:LOC116491356
uniprot id: A0A6J3DA58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AB hydrolase superfamily. Lipase family.
messages: Secreted

219594:LOC116502001
gene id: 219594:LOC116502001
uniprot id: A0A6J3EQC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor T2R family.
messages: Membrane

219594:NSUN4
gene id: 219594:NSUN4
uniprot id: A0A6J3DD89
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

219594:COL4A1
gene id: 219594:COL4A1
uniprot id: A0A6J3DGE7
uniprot id: A0A6J3DGF7
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a 'chicken-wire' meshwork together with laminins, proteoglycans and entactin/nidogen.
messages: basement membrane

219594:LOC116499164
gene id: 219594:LOC116499164
uniprot id: A0A6J3ECA4
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. SYK/ZAP-70 subfamily.

219594:SQLE
gene id: 219594:SQLE
uniprot id: A0A6J3CFF7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the squalene monooxygenase family.
messages: Catalyzes the stereospecific oxidation of squalene to (S)-2,3-epoxysqualene, and is considered to be a rate-limiting enzyme in steroid biosynthesis.
messages: Endoplasmic reticulum membrane

219594:LOC116488940
gene id: 219594:LOC116488940
uniprot id: A0A6J3CXF1
names: Subcellular Location Annotation
messages: Nucleus

219594:IMMP2L
gene id: 219594:IMMP2L
uniprot id: A0A6J3D9X9
uniprot id: A0A6J3DA03
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S26 family. IMP2 subfamily.
messages: Heterodimer of 2 subunits, IMMPL1 and IMMPL2.
messages: Membrane
messages: Mitochondrion inner membrane

219594:GALNT7
gene id: 219594:GALNT7
uniprot id: A0A6J3CVN4
uniprot id: A0A6J3CW40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

219594:MPZ
gene id: 219594:MPZ
uniprot id: A0A6J3EB09
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the myelin P0 protein family.
messages: Cell membrane
messages: Is an adhesion molecule necessary for normal myelination in the peripheral nervous system. It mediates adhesion between adjacent myelin wraps and ultimately drives myelin compaction.
messages: Membrane

219594:MAP1LC3A
gene id: 219594:MAP1LC3A
uniprot id: A0A6J3DXI1
names: Similarity
messages: Belongs to the ATG8 family.

219594:POU3F2
gene id: 219594:POU3F2
uniprot id: A0A6J3CUH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POU transcription factor family. Class-3 subfamily.
messages: Nucleus

219594:CROT
gene id: 219594:CROT
uniprot id: A0A6J3CNH0
names: Similarity
messages: Belongs to the carnitine/choline acetyltransferase family.

219594:CASK
gene id: 219594:CASK
uniprot id: A0A6J3DG42
uniprot id: A0A6J3DK30
uniprot id: A0A6J3DK51
uniprot id: A0A6J3DK66
uniprot id: A0A6J3DK75
uniprot id: A0A6J3DLQ5
uniprot id: A0A6J3DM43
names: Similarity
messages: Belongs to the MAGUK family.

219594:DMD
gene id: 219594:DMD
uniprot id: A0A6J3DBY7
uniprot id: A0A6J3DC38
uniprot id: A0A6J3DC48
uniprot id: A0A6J3DEM5
uniprot id: A0A6J3DFS9
uniprot id: A0A6J3DFW3
uniprot id: A0A6J3DFZ3
uniprot id: A0A6J3DHJ5
uniprot id: A0A6J3DI36
names: Function
names: Subcellular Location Annotation
messages: May play a role in anchoring the cytoskeleton to the plasma membrane.
messages: cytoskeleton

219594:AFAP1L1
gene id: 219594:AFAP1L1
uniprot id: A0A6J3DMR7
uniprot id: A0A6J3DSW7
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: May be involved in podosome and invadosome formation.
messages: invadopodium
messages: podosome

219594:MLEC
gene id: 219594:MLEC
uniprot id: A0A6J3DX02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the malectin family.
messages: Endoplasmic reticulum membrane
messages: Membrane

219594:ATRX
gene id: 219594:ATRX
uniprot id: A0A6J3DKJ9
uniprot id: A0A6J3DPT7
uniprot id: A0A6J3DRU2
names: Subcellular Location Annotation
messages: Nucleus
messages: telomere

219594:LOC116501299
gene id: 219594:LOC116501299
uniprot id: A0A6J3EHL5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:COQ8A
gene id: 219594:COQ8A
uniprot id: A0A6J3CT09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. ADCK protein kinase family.
messages: Membrane
messages: Mitochondrion

219594:DLX4
gene id: 219594:DLX4
uniprot id: A0A6J3E6S6
names: Subcellular Location Annotation
messages: Nucleus

219594:IGF2BP3
gene id: 219594:IGF2BP3
uniprot id: A0A6J3CJB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM IMP/VICKZ family.
messages: Cytoplasm
messages: Nucleus

219594:LRRFIP2
gene id: 219594:LRRFIP2
uniprot id: A0A6J3CEJ1
uniprot id: A0A6J3CEJ6
uniprot id: A0A6J3CG69
uniprot id: A0A6J3CH51
uniprot id: A0A6J3CH56
uniprot id: A0A6J3CJ36
uniprot id: A0A6J3CKT0
uniprot id: A0A6J3CKT9
names: Similarity
messages: Belongs to the LRRFIP family.

219594:USP44
gene id: 219594:USP44
uniprot id: A0A6J3DUC8
names: Similarity
messages: Belongs to the peptidase C19 family.

219594:MED15
gene id: 219594:MED15
uniprot id: A0A6J3DY31
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 15 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

219594:TMED4
gene id: 219594:TMED4
uniprot id: A0A6J3E8P1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Endoplasmic reticulum membrane
messages: Membrane

219594:LOC116500621
gene id: 219594:LOC116500621
uniprot id: A0A6J3EEI6
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

219594:GDI2
gene id: 219594:GDI2
uniprot id: A0A6J3DNL9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Rab GDI family.
messages: Cytoplasm
messages: Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP.

219594:PMF1
gene id: 219594:PMF1
uniprot id: A0A6J3EFV6
names: Subcellular Location Annotation
messages: Nucleus
messages: kinetochore

219594:KCNA4
gene id: 219594:KCNA4
uniprot id: A0A6J3D359
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the potassium channel family. A (Shaker) (TC 1.A.1.2) subfamily. Kv1.4/KCNA4 sub-subfamily.
messages: Cell membrane
messages: Membrane
messages: axon

219594:LOC116490513
gene id: 219594:LOC116490513
uniprot id: A0A6J3D592
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
messages: cytoskeleton

219594:LOC116492460
gene id: 219594:LOC116492460
uniprot id: A0A6J3DF07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Cytoplasm

219594:ELF2
gene id: 219594:ELF2
uniprot id: A0A6J3CXS0
uniprot id: A0A6J3D032
uniprot id: A0A6J3D188
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

219594:DNM3
gene id: 219594:DNM3
uniprot id: A0A6J3DB68
uniprot id: A0A6J3DDS5
uniprot id: A0A6J3DEV6
uniprot id: A0A6J3DH43
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.

219594:MEX3A
gene id: 219594:MEX3A
uniprot id: A0A6J3EEW4
names: Subcellular Location Annotation
messages: Cytoplasm

219594:PGPEP1L
gene id: 219594:PGPEP1L
uniprot id: A0A6J3DGV4
names: Similarity
messages: Belongs to the peptidase C15 family.

219594:MALRD1
gene id: 219594:MALRD1
uniprot id: A0A6J3CI88
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:PAMR1
gene id: 219594:PAMR1
uniprot id: A0A6J3D2L4
uniprot id: A0A6J3D2U5
uniprot id: A0A6J3D553
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:RHBDL3
gene id: 219594:RHBDL3
uniprot id: A0A6J3DVR8
uniprot id: A0A6J3DXL7
uniprot id: A0A6J3DZX6
uniprot id: A0A6J3E1V4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S54 family.
messages: Membrane

219594:AMT
gene id: 219594:AMT
uniprot id: A0A6J3DHV8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GcvT family.
messages: Mitochondrion
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

219594:MINDY1
gene id: 219594:MINDY1
uniprot id: A0A6J3E9T9
names: Function
names: Similarity
messages: Belongs to the MINDY deubiquitinase family. FAM63 subfamily.
messages: Hydrolase that can specifically remove 'Lys-48'-linked conjugated ubiquitin from proteins. Has exodeubiquitinase activity and has a preference for long polyubiquitin chains. May play a regulatory role at the level of protein turnover.

219594:UCHL3
gene id: 219594:UCHL3
uniprot id: A0A6J3CJQ9
uniprot id: A0A6J3CJS3
uniprot id: A0A6J3CPE2
names: Similarity
messages: Belongs to the peptidase C12 family.

219594:LOC116501262
gene id: 219594:LOC116501262
uniprot id: A0A6J3EG18
uniprot id: A0A6J3ELD8
names: Similarity
messages: Belongs to the ARTD/PARP family.

219594:WNT16
gene id: 219594:WNT16
uniprot id: A0A6J3EIJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

219594:FOXO6
gene id: 219594:FOXO6
uniprot id: A0A6J3E8Q5
names: Subcellular Location Annotation
messages: Nucleus

219594:LOC116495787
gene id: 219594:LOC116495787
uniprot id: A0A6J3DWV1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for thyrotropin-releasing hormone (TRH). Upon ligand binding, this G-protein-coupled receptor triggers activation of the phosphatidylinositol (IP3)-calcium-protein kinase C (PKC) pathway.

219594:COX2
gene id: 219594:COX2
uniprot id: A0A068L8F7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Binds a copper A center.
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
messages: Membrane
messages: Mitochondrion inner membrane

219594:TMEM201
gene id: 219594:TMEM201
uniprot id: A0A6J3E0N3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM201 family.
messages: Membrane
messages: Nucleus inner membrane

219594:GPR65
gene id: 219594:GPR65
uniprot id: A0A6J3D4X1
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

219594:OCIAD1
gene id: 219594:OCIAD1
uniprot id: A0A6J3CTK8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OCIAD1 family.
messages: Endosome
messages: Interacts with STAT3.
messages: Maintains stem cell potency. Increases STAT3 phosphorylation and controls ERK phosphorylation. May act as a scaffold, increasing STAT3 recruitment onto endosomes.
messages: The OCIA domain is necessary and sufficient for endosomal localization.

219594:LOC116487663
gene id: 219594:LOC116487663
uniprot id: A0A6J3CTK9
names: Similarity
messages: Belongs to the cytochrome P450 family.

219594:ATP2A3
gene id: 219594:ATP2A3
uniprot id: A0A6J3DYS5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIA subfamily.
messages: Catalyzes the hydrolysis of ATP coupled with the transport of calcium.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Sarcoplasmic reticulum membrane

219594:SRC
gene id: 219594:SRC
uniprot id: A0A6J3DUZ4
uniprot id: A0A6J3DXZ2
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

219594:LOC116493480
gene id: 219594:LOC116493480
uniprot id: A0A6J3DNA6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Generates hydrogen peroxide which is required for the activity of thyroid peroxidase/TPO and lactoperoxidase/LPO. Plays a role in thyroid hormones synthesis and lactoperoxidase-mediated antimicrobial defense at the surface of mucosa. May have its own peroxidase activity through its N-terminal peroxidase-like domain.
messages: In the N-terminal section; belongs to the peroxidase family.
messages: Membrane

219594:CPLANE2
gene id: 219594:CPLANE2
uniprot id: A0A6J3E6S7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Potential effector of the planar cell polarity signaling pathway. Plays a role in targeted membrane trafficking most probably at the level of vesicle fusion with membranes. Involved in cilium biogenesis by regulating the transport of cargo proteins to the basal body and to the apical tips of cilia. More generally involved in exocytosis in secretory cells.
messages: cilium basal body

219594:LOC116502093
gene id: 219594:LOC116502093
uniprot id: A0A6J3EIZ9
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

219594:SOGA1
gene id: 219594:SOGA1
uniprot id: A0A6J3DUM8
names: Similarity
messages: Belongs to the SOGA family.

219594:DIO3
gene id: 219594:DIO3
uniprot id: A0A6J3D6B4
names: Function
names: Similarity
messages: Belongs to the iodothyronine deiodinase family.
messages: Responsible for the deiodination of T4 (3,5,3',5'-tetraiodothyronine).

219594:PTPA
gene id: 219594:PTPA
uniprot id: A0A6J3E2M3
uniprot id: A0A6J3E3Q0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PTPA-type PPIase family.
messages: Cytoplasm
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

219594:AMDHD2
gene id: 219594:AMDHD2
uniprot id: A0A6J3DQN6
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

219594:ELP2
gene id: 219594:ELP2
uniprot id: A0A6J3CGU9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat ELP2 family.
messages: Cytoplasm
messages: Nucleus

219594:ASXL2
gene id: 219594:ASXL2
uniprot id: A0A6J3CP04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Asx family.
messages: Nucleus

219594:E2F6
gene id: 219594:E2F6
uniprot id: A0A6J3CT82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the E2F/DP family.
messages: Nucleus

219594:VPS41
gene id: 219594:VPS41
uniprot id: A0A6J3CD63
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS41 family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane
messages: Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport pathways.
messages: Vesicle
messages: clathrin-coated vesicle
messages: trans-Golgi network

219594:RANBP17
gene id: 219594:RANBP17
uniprot id: A0A6J3DQM6
uniprot id: A0A6J3DUD6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exportin family.
messages: Cytoplasm
messages: Nucleus

219594:C19H9orf116
gene id: 219594:C19H9orf116
uniprot id: A0A6J3DYD9
names: Subcellular Location Annotation
messages: cilium axoneme

219594:MYO1B
gene id: 219594:MYO1B
uniprot id: A0A6J3D4V1
uniprot id: A0A6J3D808
uniprot id: A0A6J3D811
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

219594:IRF2
gene id: 219594:IRF2
uniprot id: A0A6J3D0K9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IRF family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

219594:LOC116489859
gene id: 219594:LOC116489859
uniprot id: A0A6J3D1Y0
names: Similarity
messages: Belongs to the cytochrome P450 family.

219594:SLC37A3
gene id: 219594:SLC37A3
uniprot id: A0A6J3DUG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family.
messages: Membrane

219594:DDX27
gene id: 219594:DDX27
uniprot id: A0A6J3DSD7
names: Similarity
messages: Belongs to the DEAD box helicase family.

219594:PPP1CC
gene id: 219594:PPP1CC
uniprot id: A0A6J3DVB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PPP phosphatase family. PP-1 subfamily.
messages: Cleavage furrow
messages: Cytoplasm
messages: Midbody

219594:DRAXIN
gene id: 219594:DRAXIN
uniprot id: A0A6J3E2L5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the draxin family.
messages: Chemorepulsive axon guidance protein required for the development of spinal cord and forebrain commissures. Acts as a chemorepulsive guidance protein for commissural axons during development. Able to inhibit or repel neurite outgrowth from dorsal spinal cord.
messages: Secreted

219594:AK5
gene id: 219594:AK5
uniprot id: A0A6J3DG46
names: Similarity
messages: Belongs to the adenylate kinase family.

219594:KDELR3
gene id: 219594:KDELR3
uniprot id: A0A6J3DKY7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERD2 family.
messages: COPI-coated vesicle membrane
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

219594:MMP23B
gene id: 219594:MMP23B
uniprot id: A0A6J3E0N9
uniprot id: A0A6J3E4W8
uniprot id: A0A6J3E5P0
names: Caution
names: Similarity
messages: Belongs to the peptidase M10A family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:HGFAC
gene id: 219594:HGFAC
uniprot id: A0A6J3CV30
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:ATP6AP1
gene id: 219594:ATP6AP1
uniprot id: A0A6J3EC79
names: Similarity
messages: Belongs to the vacuolar ATPase subunit S1 family.

219594:CADM2
gene id: 219594:CADM2
uniprot id: A0A6J3EQ92
uniprot id: A0A6J3ERQ5
names: Similarity
messages: Belongs to the nectin family.

219594:LOC116496104
gene id: 219594:LOC116496104
uniprot id: A0A6J3DZ08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
messages: Cleavage furrow
messages: Midbody
messages: cilium membrane
messages: spindle

219594:IL16
gene id: 219594:IL16
uniprot id: A0A6J3DGH3
uniprot id: A0A6J3DGH8
uniprot id: A0A6J3DJ49
uniprot id: A0A6J3DKH4
uniprot id: A0A6J3DKI0
uniprot id: A0A6J3DM11
uniprot id: A0A6J3DMI1
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Homotetramer.
messages: Interleukin-16 stimulates a migratory response in CD4+ lymphocytes, monocytes, and eosinophils. Primes CD4+ T-cells for IL-2 and IL-15 responsiveness. Also induces T-lymphocyte expression of interleukin 2 receptor. Ligand for CD4.
messages: Nucleus
messages: Secreted

219594:CRAT
gene id: 219594:CRAT
uniprot id: A0A6J3DYV3
uniprot id: A0A6J3E182
names: Similarity
messages: Belongs to the carnitine/choline acetyltransferase family.

219594:UBE3A
gene id: 219594:UBE3A
uniprot id: A0A6J3CX95
uniprot id: A0A6J3D275
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and transfers it to its substrates.
messages: Nucleus

219594:EFNA4
gene id: 219594:EFNA4
uniprot id: A0A6J3EDN2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ephrin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

219594:STAT6
gene id: 219594:STAT6
uniprot id: A0A6J3EFH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transcription factor STAT family.
messages: Cytoplasm
messages: Nucleus

219594:GTF3C5
gene id: 219594:GTF3C5
uniprot id: A0A6J3E4D3
names: Subcellular Location Annotation
messages: Nucleus

219594:ZNF330
gene id: 219594:ZNF330
uniprot id: A0A6J3D1J7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOA36 family.
messages: nucleolus

219594:ADAMTS5
gene id: 219594:ADAMTS5
uniprot id: A0A6J3DD22
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

219594:LOC116488125
gene id: 219594:LOC116488125
uniprot id: A0A6J3CTC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-17 family.
messages: Secreted

219594:LOC116500058
gene id: 219594:LOC116500058
uniprot id: A0A6J3ECA2
names: Similarity
messages: Belongs to the ATG8 family.

219594:MAPK8IP3
gene id: 219594:MAPK8IP3
uniprot id: A0A6J3DPY6
uniprot id: A0A6J3DPZ3
uniprot id: A0A6J3DPZ8
uniprot id: A0A6J3DQ04
uniprot id: A0A6J3DQ08
uniprot id: A0A6J3DS83
uniprot id: A0A6J3DS88
uniprot id: A0A6J3DS98
uniprot id: A0A6J3DSA3
uniprot id: A0A6J3DUA4
uniprot id: A0A6J3DUB2
uniprot id: A0A6J3DUC1
uniprot id: A0A6J3DUC6
uniprot id: A0A6J3DUD1
uniprot id: A0A6J3DV73
uniprot id: A0A6J3DV78
uniprot id: A0A6J3DV80
uniprot id: A0A6J3DV85
uniprot id: A0A6J3DV92
uniprot id: A0A6J3DW34
uniprot id: A0A6J3DW40
uniprot id: A0A6J3DW46
uniprot id: A0A6J3DW53
uniprot id: A0A6J3DW58
names: Similarity
messages: Belongs to the JIP scaffold family.

219594:SDC3
gene id: 219594:SDC3
uniprot id: A0A6J3E3Y8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the syndecan proteoglycan family.
messages: Cell surface proteoglycan.
messages: Membrane

219594:JPT1
gene id: 219594:JPT1
uniprot id: A0A6J3E100
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the JUPITER family.
messages: Cytoplasm
messages: Nucleus

219594:ND6
gene id: 219594:ND6
uniprot id: A0A068L9C2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I.
messages: Mitochondrion membrane

219594:HSBP1
gene id: 219594:HSBP1
uniprot id: A0A6J3DJE6
names: Similarity
messages: Belongs to the HSBP1 family.

219594:APOA4
gene id: 219594:APOA4
uniprot id: A0A6J3E692
names: Similarity
messages: Belongs to the apolipoprotein A1/A4/E family.

219594:NDUFAF2
gene id: 219594:NDUFAF2
uniprot id: A0A6J3EI14
names: Similarity
messages: Belongs to the complex I NDUFA12 subunit family.

219594:TMEM11
gene id: 219594:TMEM11
uniprot id: A0A6J3DV59
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM11 family.
messages: Membrane
messages: Mitochondrion inner membrane
messages: Plays a role in mitochondrial morphogenesis.

219594:CNRIP1
gene id: 219594:CNRIP1
uniprot id: A0A6J3CT02
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CNRIP family.
messages: Interacts with the cannabinoid receptor CNR1 (via C-terminus). Does not interact with cannabinoid receptor CNR2.
messages: Suppresses cannabinoid receptor CNR1-mediated tonic inhibition of voltage-gated calcium channels.

219594:MAML1
gene id: 219594:MAML1
uniprot id: A0A6J3DTC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mastermind family.
messages: Nucleus speckle

219594:LOC116487934
gene id: 219594:LOC116487934
uniprot id: A0A6J3CUW1
names: Similarity
names: Subcellular Location Annotation
messages: Basolateral cell membrane
messages: Belongs to the potassium channel family. KQT (TC 1.A.1.15) subfamily. Kv7.1/KCNQ1 sub-subfamily.
messages: Cell membrane
messages: Cytoplasmic vesicle membrane
messages: Endoplasmic reticulum
messages: Lateral cell membrane
messages: Membrane
messages: Membrane raft

219594:CENPM
gene id: 219594:CENPM
uniprot id: A0A6J3EIP1
names: Subcellular Location Annotation
messages: Nucleus

219594:ATP13A1
gene id: 219594:ATP13A1
uniprot id: A0A6J3EG47
names: Similarity
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily.

219594:PDF
gene id: 219594:PDF
uniprot id: A0A6J3DR43
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins.

219594:RPRD1A
gene id: 219594:RPRD1A
uniprot id: A0A6J3CE40
names: Similarity
messages: Belongs to the UPF0400 (RTT103) family.

219594:LOC116500003
gene id: 219594:LOC116500003
uniprot id: A0A6J3EAR9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

219594:XKR6
gene id: 219594:XKR6
uniprot id: A0A6J3CVN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XK family.
messages: Membrane

219594:IL17D
gene id: 219594:IL17D
uniprot id: A0A6J3EN11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-17 family.
messages: Secreted

219594:LOC116499668
gene id: 219594:LOC116499668
uniprot id: A0A6J3E9H2
names: Similarity
names: Subunit
messages: Belongs to the avian keratin family.
messages: The avian keratins (F-ker, S-ker, C-ker and B-ker) are a complex mixture of very similar polypeptides.

219594:DUSP5
gene id: 219594:DUSP5
uniprot id: A0A6J3DAC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
messages: Nucleus

219594:LOC116498862
gene id: 219594:LOC116498862
uniprot id: A0A6J3E6C3
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family. Chitinase class II subfamily.

219594:RAX2
gene id: 219594:RAX2
uniprot id: A0A6J3EEN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paired homeobox family. Bicoid subfamily.
messages: Nucleus

219594:TAAR2
gene id: 219594:TAAR2
uniprot id: A0A6J3CSV3
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

219594:DAZL
gene id: 219594:DAZL
uniprot id: A0A6J3CER8
names: Subcellular Location Annotation
messages: Cytoplasm

219594:PPP2R5A
gene id: 219594:PPP2R5A
uniprot id: A0A6J3CKV0
names: Similarity
messages: Belongs to the phosphatase 2A regulatory subunit B56 family.

219594:MANBA
gene id: 219594:MANBA
uniprot id: A0A6J3CX32
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycosyl hydrolase 2 family.
messages: Exoglycosidase that cleaves the single beta-linked mannose residue from the non-reducing end of all N-linked glycoprotein oligosaccharides.
messages: Lysosome
messages: Monomer.

219594:NELFCD
gene id: 219594:NELFCD
uniprot id: A0A6J3DWM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NELF-D family.
messages: Nucleus

219594:PTP4A2
gene id: 219594:PTP4A2
uniprot id: A0A6J3E3E9
names: Subcellular Location Annotation
messages: Early endosome
messages: Endosome

219594:CCKBR
gene id: 219594:CCKBR
uniprot id: A0A6J3EPY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:SEMA3D
gene id: 219594:SEMA3D
uniprot id: A0A6J3EHV0
uniprot id: A0A6J3EN29
names: Caution
names: Similarity
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:LOC116501340
gene id: 219594:LOC116501340
uniprot id: A0A6J3ELK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:ENTPD1
gene id: 219594:ENTPD1
uniprot id: A0A6J3D6A8
uniprot id: A0A6J3D9K2
names: Similarity
messages: Belongs to the GDA1/CD39 NTPase family.

219594:PHPT1
gene id: 219594:PHPT1
uniprot id: A0A6J3E4K6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the janus family.
messages: Cytoplasm
messages: Exhibits phosphohistidine phosphatase activity.
messages: Monomer.

219594:SMAGP
gene id: 219594:SMAGP
uniprot id: A0A6J3EAT0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMAGP family.
messages: Cell membrane
messages: Cytoplasmic vesicle membrane
messages: Membrane

219594:PSMA5
gene id: 219594:PSMA5
uniprot id: A0A6J3EB38
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Cytoplasm
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.

219594:SNX18
gene id: 219594:SNX18
uniprot id: A0A6J3EFT1
uniprot id: A0A6J3EL36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Cytoplasmic vesicle membrane

219594:OPRM1
gene id: 219594:OPRM1
uniprot id: A0A6J3CTJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Perikaryon
messages: axon
messages: dendrite

219594:FOXL1
gene id: 219594:FOXL1
uniprot id: A0A6J3DNU3
names: Subcellular Location Annotation
messages: Nucleus

219594:CDH6
gene id: 219594:CDH6
uniprot id: A0A6J3CJG7
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane
messages: Membrane

219594:RIPOR1
gene id: 219594:RIPOR1
uniprot id: A0A6J3DJU0
uniprot id: A0A6J3DMC2
uniprot id: A0A6J3DP23
names: Similarity
messages: Belongs to the RIPOR family.

219594:GATA6
gene id: 219594:GATA6
uniprot id: A0A6J3CMU9
names: Subcellular Location Annotation
messages: Nucleus

219594:ISL2
gene id: 219594:ISL2
uniprot id: A0A6J3DJX2
names: Subcellular Location Annotation
messages: Nucleus

219594:LOC116498337
gene id: 219594:LOC116498337
uniprot id: A0A6J3E5P2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family.
messages: Secreted

219594:SNTA1
gene id: 219594:SNTA1
uniprot id: A0A6J3DTX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the syntrophin family.
messages: Cell junction
messages: cytoskeleton

219594:SCNN1D
gene id: 219594:SCNN1D
uniprot id: A0A6J3E4Y1
names: Subcellular Location Annotation
messages: Membrane

219594:ERO1B
gene id: 219594:ERO1B
uniprot id: A0A6J3CKY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EROs family.
messages: Endoplasmic reticulum membrane

219594:KIAA1324L
gene id: 219594:KIAA1324L
uniprot id: A0A6J3DGW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELAPOR family.
messages: Cell membrane
messages: Membrane

219594:RAPSN
gene id: 219594:RAPSN
uniprot id: A0A6J3D1H5
uniprot id: A0A6J3D3V3
names: Similarity
messages: Belongs to the RAPsyn family.

219594:ADAMTS12
gene id: 219594:ADAMTS12
uniprot id: A0A6J3ECX0
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

219594:LOC116496321
gene id: 219594:LOC116496321
uniprot id: A0A6J3DV14
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

219594:LOC116490622
gene id: 219594:LOC116490622
uniprot id: A0A6J3D3G2
uniprot id: A0A6J3D9C2
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

219594:GDAP1
gene id: 219594:GDAP1
uniprot id: A0A6J3CFW8
names: Similarity
messages: Belongs to the GST superfamily.

219594:BOD1
gene id: 219594:BOD1
uniprot id: A0A6J3DQR4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BOD1 family.
messages: centrosome
messages: kinetochore

219594:CLDN2
gene id: 219594:CLDN2
uniprot id: A0A6J3DMT4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

219594:DKC1
gene id: 219594:DKC1
uniprot id: A0A6J3DLJ2
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family.

219594:GALNT13
gene id: 219594:GALNT13
uniprot id: A0A6J3D600
uniprot id: A0A6J3D9B3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

219594:DUS4L
gene id: 219594:DUS4L
uniprot id: A0A6J3DHC8
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs.

219594:NF2
gene id: 219594:NF2
uniprot id: A0A6J3DUV9
uniprot id: A0A6J3DWN5
uniprot id: A0A6J3DZQ6
uniprot id: A0A6J3E0S7
names: Subcellular Location Annotation
messages: Membrane
messages: cytoskeleton

219594:LOC116490106
gene id: 219594:LOC116490106
uniprot id: A0A6J3D0U6
names: Caution
names: Cofactor
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:CFAP53
gene id: 219594:CFAP53
uniprot id: A0A6J3EHK5
names: Similarity
messages: Belongs to the CFAP53 family.

219594:NUDT7
gene id: 219594:NUDT7
uniprot id: A0A6J3DJJ5
uniprot id: A0A6J3DQ02
names: Similarity
messages: Belongs to the Nudix hydrolase family. PCD1 subfamily.

219594:TFAP2A
gene id: 219594:TFAP2A
uniprot id: A0A6J3CMI6
uniprot id: A0A6J3CPK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AP-2 family.
messages: Nucleus

219594:ATOH7
gene id: 219594:ATOH7
uniprot id: A0A6J3D8I4
names: Subcellular Location Annotation
messages: Nucleus
messages: Perikaryon
messages: axon

219594:PTPRT
gene id: 219594:PTPRT
uniprot id: A0A6J3DRI0
uniprot id: A0A6J3DRI5
uniprot id: A0A6J3DTP6
uniprot id: A0A6J3DTQ0
uniprot id: A0A6J3DVV2
uniprot id: A0A6J3DVV8
uniprot id: A0A6J3DWP3
uniprot id: A0A6J3DXN5
uniprot id: A0A6J3DXP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Receptor class 2B subfamily.
messages: Membrane

219594:AACS
gene id: 219594:AACS
uniprot id: A0A6J3DWH1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Converts acetoacetate to acetoacetyl-CoA in the cytosol.
messages: cytosol

219594:HOXB7
gene id: 219594:HOXB7
uniprot id: A0A6J3E5E3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus

219594:RGR
gene id: 219594:RGR
uniprot id: A0A6J3DAG8
names: Subcellular Location Annotation
messages: Membrane

219594:GDAP2
gene id: 219594:GDAP2
uniprot id: A0A6J3DH94
names: Similarity
messages: Belongs to the GDAP2 family.

219594:SUPT3H
gene id: 219594:SUPT3H
uniprot id: A0A6J3CTT9
names: Subcellular Location Annotation
messages: Nucleus

219594:HAPLN3
gene id: 219594:HAPLN3
uniprot id: A0A6J3DHZ9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:MYOZ3
gene id: 219594:MYOZ3
uniprot id: A0A6J3DPH3
names: Similarity
messages: Belongs to the myozenin family.

219594:LOC116502216
gene id: 219594:LOC116502216
uniprot id: A0A6J3EKU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPOT14 family.
messages: Cytoplasm
messages: Nucleus

219594:SEPHS1
gene id: 219594:SEPHS1
uniprot id: A0A6J3EI55
names: Function
messages: Synthesizes selenophosphate from selenide and ATP.

219594:NIBAN2
gene id: 219594:NIBAN2
uniprot id: A0A6J3DYI1
names: Similarity
messages: Belongs to the Niban family.

219594:BCL2A1
gene id: 219594:BCL2A1
uniprot id: A0A6J3DKK4
names: Similarity
messages: Belongs to the Bcl-2 family.

219594:LOC116501297
gene id: 219594:LOC116501297
uniprot id: A0A6J3EG49
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:PANX2
gene id: 219594:PANX2
uniprot id: A0A6J3D8G2
uniprot id: A0A6J3DB32
uniprot id: A0A6J3DBN1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pannexin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Structural component of the gap junctions and the hemichannels.
messages: gap junction

219594:FAM120B
gene id: 219594:FAM120B
uniprot id: A0A6J3CSK3
names: Similarity
messages: Belongs to the constitutive coactivator of PPAR-gamma family.

219594:LOC116485542
gene id: 219594:LOC116485542
uniprot id: A0A6J3CFR1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
messages: cytoskeleton

219594:LOC116497551
gene id: 219594:LOC116497551
uniprot id: A0A6J3E2B6
names: Similarity
messages: Belongs to the 'GDXG' lipolytic enzyme family.

219594:BPIFC
gene id: 219594:BPIFC
uniprot id: A0A6J3CGV6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family.
messages: Monomer. Homodimer; disulfide-linked.
messages: Secreted
messages: The N- and C-terminal barrels adopt an identical fold despite having only 13% of conserved residues.
messages: The N-terminal region may be exposed to the interior of the granule, whereas the C-terminal portion may be embedded in the membrane. During phagocytosis and degranulation, proteases may be released and activated and cleave BPI at the junction of the N- and C-terminal portions of the molecule, providing controlled release of the N-terminal antibacterial fragment when bacteria are ingested.
messages: The cytotoxic action of BPI is limited to many species of Gram-negative bacteria; this specificity may be explained by a strong affinity of the very basic N-terminal half for the negatively charged lipopolysaccharides that are unique to the Gram-negative bacterial outer envelope.

219594:ADGRV1
gene id: 219594:ADGRV1
uniprot id: A0A6J3EHF2
names: Subcellular Location Annotation
messages: Membrane

219594:PDILT
gene id: 219594:PDILT
uniprot id: A0A6J3DVD5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein disulfide isomerase family.
messages: Endoplasmic reticulum lumen

219594:UCHL5
gene id: 219594:UCHL5
uniprot id: A0A6J3DDJ7
names: Similarity
messages: Belongs to the peptidase C12 family.

219594:CASKIN1
gene id: 219594:CASKIN1
uniprot id: A0A6J3DUS6
uniprot id: A0A6J3DWK2
names: Subcellular Location Annotation
messages: Cytoplasm

219594:CCDC86
gene id: 219594:CCDC86
uniprot id: A0A6J3D050
names: Subcellular Location Annotation
messages: Nucleus

219594:UTP6
gene id: 219594:UTP6
uniprot id: A0A6J3E1W2
names: Similarity
messages: Belongs to the UTP6 family.

219594:RRS1
gene id: 219594:RRS1
uniprot id: A0A6J3CHY3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRS1 family.
messages: Involved in ribosomal large subunit assembly.
messages: Nucleus

219594:RPS16
gene id: 219594:RPS16
uniprot id: A0A6J3ERD9
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

219594:LZTFL1
gene id: 219594:LZTFL1
uniprot id: A0A6J3CF09
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LZTFL1 family.
messages: Cytoplasm
messages: Regulates ciliary localization of the BBSome complex. Together with the BBSome complex, controls SMO ciliary trafficking and contributes to the sonic hedgehog (SHH) pathway regulation. May play a role in neurite outgrowth. May have tumor suppressor function.
messages: Self-associates. Interacts with BBS9; the interaction mediates the association of LZTL1 with the BBsome complex and regulates BBSome ciliary trafficking.

219594:LOC116490909
gene id: 219594:LOC116490909
uniprot id: A0A6J3D7J8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UDP-glycosyltransferase family.
messages: Membrane

219594:VHL
gene id: 219594:VHL
uniprot id: A0A6J3DFB4
names: Similarity
messages: Belongs to the VHL family.

219594:PARP3
gene id: 219594:PARP3
uniprot id: A0A6J3DHI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ARTD/PARP family.
messages: Nucleus

219594:ARHGDIG
gene id: 219594:ARHGDIG
uniprot id: A0A6J3DQU0
names: Similarity
messages: Belongs to the Rho GDI family.

219594:CDH13
gene id: 219594:CDH13
uniprot id: A0A6J3DIF9
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: By contrast to classical cadherins, homodimerization in trans is not mediated by cadherin EC1 domain strand-swapping, but instead through a homophilic adhesive interface which joins two elongated EC1-EC2 domains through a region near their Ca2+-binding sites to form a tetrahedral, X-like shape.
messages: Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. May act as a negative regulator of neural cell growth.
messages: Cell membrane
messages: Membrane

219594:MAN2A1
gene id: 219594:MAN2A1
uniprot id: A0A6J3EKG8
names: Cofactor
names: Similarity
messages: Belongs to the glycosyl hydrolase 38 family.
messages: Binds 1 zinc ion per subunit.

219594:ADAM11
gene id: 219594:ADAM11
uniprot id: A0A6J3E4J0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:FA2H
gene id: 219594:FA2H
uniprot id: A0A6J3DIW6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sterol desaturase family. SCS7 subfamily.
messages: Binds 2 Zn(2+) ions per subunit that likely form a catalytic dimetal center.
messages: Catalyzes stereospecific hydroxylation of free fatty acids at the C-2 position to produce (R)-2-hydroxy fatty acids, which are building blocks of sphingolipids and glycosphingolipids common in neural tissue and epidermis. Plays an essential role in the synthesis of galactosphingolipids of the myelin sheath. Responsible for the synthesis of sphingolipids and glycosphingolipids involved in the formation of epidermal lamellar bodies critical for skin permeability barrier. Participates in the synthesis of glycosphingolipids and a fraction of type II wax diesters in sebaceous gland, specifically regulating hair follicle homeostasis. Involved in the synthesis of sphingolipids of plasma membrane rafts, controlling lipid raft mobility and trafficking of raft-associated proteins.
messages: Endoplasmic reticulum membrane
messages: Membrane

219594:SCN8A
gene id: 219594:SCN8A
uniprot id: A0A6J3EFF7
uniprot id: A0A6J3EH37
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium channel (TC 1.A.1.10) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.
messages: Membrane

219594:MFNG
gene id: 219594:MFNG
uniprot id: A0A6J3EK44
uniprot id: A0A6J3EK87
uniprot id: A0A6J3EK97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

219594:ATP6V0A4
gene id: 219594:ATP6V0A4
uniprot id: A0A6J3EHZ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase 116 kDa subunit family.
messages: Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.
messages: Membrane

219594:JAG2
gene id: 219594:JAG2
uniprot id: A0A6J3D057
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Putative Notch ligand involved in the mediation of Notch signaling.

219594:SGCD
gene id: 219594:SGCD
uniprot id: A0A6J3DMG8
uniprot id: A0A6J3DPT2
uniprot id: A0A6J3DTQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sarcoglycan beta/delta/gamma/zeta family.
messages: cytoskeleton
messages: sarcolemma

219594:SLC26A7
gene id: 219594:SLC26A7
uniprot id: A0A6J3CIW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

219594:ZDHHC18
gene id: 219594:ZDHHC18
uniprot id: A0A6J3E7T4
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

219594:VPS35
gene id: 219594:VPS35
uniprot id: A0A6J3DMN0
names: Function
names: Similarity
messages: Belongs to the VPS35 family.
messages: Plays a role in vesicular protein sorting.

219594:LOC116495373
gene id: 219594:LOC116495373
uniprot id: A0A6J3DUQ7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:LOC116501882
gene id: 219594:LOC116501882
uniprot id: A0A6J3ENC5
names: Similarity
messages: Belongs to the CRISP family.

219594:KIF16B
gene id: 219594:KIF16B
uniprot id: A0A6J3CLK8
uniprot id: A0A6J3CN89
uniprot id: A0A6J3CP83
uniprot id: A0A6J3CRI2
uniprot id: A0A6J3CSI2
uniprot id: A0A6J3CSI7
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

219594:ALDH18A1
gene id: 219594:ALDH18A1
uniprot id: A0A6J3D6V1
uniprot id: A0A6J3D9J4
names: Similarity
messages: In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family.
messages: In the N-terminal section; belongs to the glutamate 5-kinase family.

219594:UTP14A
gene id: 219594:UTP14A
uniprot id: A0A6J3DR79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UTP14 family.
messages: nucleolus

219594:RFTN1
gene id: 219594:RFTN1
uniprot id: A0A6J3CNA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the raftlin family.
messages: Cell membrane
messages: Membrane

219594:LOC116489991
gene id: 219594:LOC116489991
uniprot id: A0A6J3D594
names: Similarity
messages: Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family.

219594:LOC116495006
gene id: 219594:LOC116495006
uniprot id: A0A6J3DNL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

219594:KIF5C
gene id: 219594:KIF5C
uniprot id: A0A6J3D9W7
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

219594:MAN2B2
gene id: 219594:MAN2B2
uniprot id: A0A6J3CX17
names: Cofactor
names: Similarity
messages: Belongs to the glycosyl hydrolase 38 family.
messages: Binds 1 zinc ion per subunit.

219594:POLL
gene id: 219594:POLL
uniprot id: A0A6J3DB89
uniprot id: A0A6J3DBR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-X family.
messages: Nucleus

219594:LOC116501350
gene id: 219594:LOC116501350
uniprot id: A0A6J3EG97
names: Subcellular Location Annotation
messages: Membrane

219594:SNTB2
gene id: 219594:SNTB2
uniprot id: A0A6J3DRD6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the syntrophin family.
messages: Cell junction
messages: cytoskeleton

219594:GOLM2
gene id: 219594:GOLM2
uniprot id: A0A6J3DJC0
uniprot id: A0A6J3DMS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GOLM family.
messages: Membrane

219594:AP2A2
gene id: 219594:AP2A2
uniprot id: A0A6J3D1Z0
uniprot id: A0A6J3D4C7
uniprot id: A0A6J3D4Q5
uniprot id: A0A6J3D6X8
uniprot id: A0A6J3D6Y3
uniprot id: A0A6J3D7T0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Adaptor protein complex 2 (AP-2) is a heterotetramer composed of two large adaptins (alpha-type subunit AP2A1 or AP2A2 and beta-type subunit AP2B1), a medium adaptin (mu-type subunit AP2M1) and a small adaptin (sigma-type subunit AP2S1).
messages: Belongs to the adaptor complexes large subunit family.
messages: Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but is itself unable to bind directly to membrane components. Clathrin-associated adaptor protein (AP) complexes which can bind directly to both the clathrin lattice and to the lipid and protein components of membranes are considered to be the major clathrin adaptors contributing the CCV formation. AP-2 also serves as a cargo receptor to selectively sort the membrane proteins involved in receptor-mediated endocytosis. AP-2 seems to play a role in the recycling of synaptic vesicle membranes from the presynaptic surface. AP-2 recognizes Y-X-X-[FILMV] (Y-X-X-Phi) and [ED]-X-X-X-L-[LI] endocytosis signal motifs within the cytosolic tails of transmembrane cargo molecules. AP-2 may also play a role in maintaining normal post-endocytic trafficking through the ARF6-regulated, non-clathrin pathway. The AP-2 alpha subunit binds polyphosphoinositide-containing lipids, positioning AP-2 on the membrane. The AP-2 alpha subunit acts via its C-terminal appendage domain as a scaffolding platform for endocytic accessory proteins. The AP-2 alpha and AP-2 sigma subunits are thought to contribute to the recognition of the [ED]-X-X-X-L-[LI] motif.
messages: coated pit

219594:HIBCH
gene id: 219594:HIBCH
uniprot id: A0A6J3D5A7
uniprot id: A0A6J3D5L9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: Hydrolyzes 3-hydroxyisobutyryl-CoA (HIBYL-CoA), a saline catabolite. Has high activity toward isobutyryl-CoA. Could be an isobutyryl-CoA dehydrogenase that functions in valine catabolism. Also hydrolyzes 3-hydroxypropanoyl-CoA.
messages: Mitochondrion

219594:PCYT1A
gene id: 219594:PCYT1A
uniprot id: A0A6J3DES8
names: Function
names: Similarity
messages: Belongs to the cytidylyltransferase family.
messages: Catalyzes the key rate-limiting step in the CDP-choline pathway for phosphatidylcholine biosynthesis.

219594:CD99
gene id: 219594:CD99
uniprot id: A0A6J3E056
uniprot id: A0A6J3E2P5
uniprot id: A0A6J3E3I3
uniprot id: A0A6J3E3J7
names: Similarity
messages: Belongs to the CD99 family.

219594:ATP1A1
gene id: 219594:ATP1A1
uniprot id: A0A6J3DM74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIC subfamily.
messages: Cell membrane

219594:IL21
gene id: 219594:IL21
uniprot id: A0A6J3CY09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-15/IL-21 family.
messages: Secreted

219594:QSOX1
gene id: 219594:QSOX1
uniprot id: A0A6J3DGN1
names: Function
names: Similarity
messages: Belongs to the quiescin-sulfhydryl oxidase (QSOX) family.
messages: Catalyzes the oxidation of sulfhydryl groups in peptide and protein thiols to disulfides with the reduction of oxygen to hydrogen peroxide.

219594:TIPIN
gene id: 219594:TIPIN
uniprot id: A0A6J3DK41
uniprot id: A0A6J3DLL0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSM3 family.
messages: Nucleus
messages: Plays an important role in the control of DNA replication and the maintenance of replication fork stability.

219594:AAR2
gene id: 219594:AAR2
uniprot id: A0A6J3DT10
names: Function
names: Similarity
messages: Belongs to the AAR2 family.
messages: Component of the U5 snRNP complex that is required for spliceosome assembly and for pre-mRNA splicing.

219594:FAM149A
gene id: 219594:FAM149A
uniprot id: A0A6J3CUX3
names: Similarity
messages: Belongs to the FAM149 family.

219594:HAPLN4
gene id: 219594:HAPLN4
uniprot id: A0A6J3EEI1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:LOC116488912
gene id: 219594:LOC116488912
uniprot id: A0A6J3CZP9
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

219594:CTSL
gene id: 219594:CTSL
uniprot id: A0A6J3EKW7
names: Similarity
messages: Belongs to the peptidase C1 family.

219594:AGBL2
gene id: 219594:AGBL2
uniprot id: A0A6J3D022
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M14 family.
messages: cytosol

219594:PNPLA1
gene id: 219594:PNPLA1
uniprot id: A0A6J3EC60
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:PPP1R14D
gene id: 219594:PPP1R14D
uniprot id: A0A6J3D171
names: Similarity
messages: Belongs to the PP1 inhibitor family.

219594:GTF2B
gene id: 219594:GTF2B
uniprot id: A0A6J3D8V5
uniprot id: A0A6J3DCH6
names: Similarity
messages: Belongs to the TFIIB family.

219594:TMEM65
gene id: 219594:TMEM65
uniprot id: A0A6J3CH35
uniprot id: A0A6J3CI40
names: Subcellular Location Annotation
messages: Membrane

219594:FAM160A1
gene id: 219594:FAM160A1
uniprot id: A0A6J3CYS6
names: Similarity
messages: Belongs to the FHIP family.

219594:VPS33A
gene id: 219594:VPS33A
uniprot id: A0A6J3DXW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STXBP/unc-18/SEC1 family.
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane

219594:WNT1
gene id: 219594:WNT1
uniprot id: A0A6J3EC03
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

219594:TATDN3
gene id: 219594:TATDN3
uniprot id: A0A6J3CNU8
uniprot id: A0A6J3CQS9
uniprot id: A0A6J3CRI1
uniprot id: A0A6J3CTS5
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.

219594:FNTA
gene id: 219594:FNTA
uniprot id: A0A6J3EJD2
names: Similarity
messages: Belongs to the protein prenyltransferase subunit alpha family.

219594:LRRC8B
gene id: 219594:LRRC8B
uniprot id: A0A6J3DEM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LRRC8 family.
messages: Cell membrane
messages: Membrane

219594:LOC116499693
gene id: 219594:LOC116499693
uniprot id: A0A6J3EED9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:SLC6A14
gene id: 219594:SLC6A14
uniprot id: A0A6J3DL49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

219594:STAR
gene id: 219594:STAR
uniprot id: A0A6J3EDA1
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: May interact with TSPO.
messages: Mitochondrion
messages: Plays a key role in steroid hormone synthesis by enhancing the metabolism of cholesterol into pregnenolone. Mediates the transfer of cholesterol from the outer mitochondrial membrane to the inner mitochondrial membrane where it is cleaved to pregnenolone.

219594:SH3RF3
gene id: 219594:SH3RF3
uniprot id: A0A6J3E8Y2
names: Similarity
messages: Belongs to the SH3RF family.

219594:PEX5L
gene id: 219594:PEX5L
uniprot id: A0A6J3DBM5
uniprot id: A0A6J3DBM9
uniprot id: A0A6J3DE93
uniprot id: A0A6J3DE97
uniprot id: A0A6J3DFE6
uniprot id: A0A6J3DFF0
uniprot id: A0A6J3DH59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxisomal targeting signal receptor family.
messages: Cytoplasm
messages: Membrane

219594:AGBL3
gene id: 219594:AGBL3
uniprot id: A0A6J3EJV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M14 family.
messages: cytosol

219594:TMEM63C
gene id: 219594:TMEM63C
uniprot id: A0A6J3D234
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSC1 (TC 1.A.17) family.
messages: Membrane

219594:MED6
gene id: 219594:MED6
uniprot id: A0A6J3D434
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 6 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

219594:OSBPL3
gene id: 219594:OSBPL3
uniprot id: A0A6J3CFS5
uniprot id: A0A6J3CHE0
uniprot id: A0A6J3CKB9
uniprot id: A0A6J3CKC5
uniprot id: A0A6J3CM16
names: Similarity
messages: Belongs to the OSBP family.

219594:ADRA2B
gene id: 219594:ADRA2B
uniprot id: A0A6J3EEZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:NXPH1
gene id: 219594:NXPH1
uniprot id: A0A6J3CM93
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neurexophilin family.
messages: May be signaling molecules that resemble neuropeptides.
messages: Secreted

219594:EPHB3
gene id: 219594:EPHB3
uniprot id: A0A6J3DIT1
uniprot id: A0A6J3DJC9
names: Subcellular Location Annotation
messages: Membrane

219594:EIF2B5
gene id: 219594:EIF2B5
uniprot id: A0A6J3DHW7
names: Similarity
messages: Belongs to the eIF-2B gamma/epsilon subunits family.

219594:MMUT
gene id: 219594:MMUT
uniprot id: A0A6J3CUN9
names: Function
names: Similarity
messages: Belongs to the methylmalonyl-CoA mutase family.
messages: Catalyzes the reversible isomerization of methylmalonyl-CoA (MMCoA) (generated from branched-chain amino acid metabolism and degradation of dietary odd chain fatty acids and cholesterol) to succinyl-CoA (3-carboxypropionyl-CoA), a key intermediate of the tricarboxylic acid cycle.

219594:CSE1L
gene id: 219594:CSE1L
uniprot id: A0A6J3DTF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XPO2/CSE1 family.
messages: Cytoplasm

219594:CELSR3
gene id: 219594:CELSR3
uniprot id: A0A6J3DLE5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily.
messages: Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Receptor that may have an important role in cell/cell signaling during nervous system formation.

219594:RASSF1
gene id: 219594:RASSF1
uniprot id: A0A6J3DHI4
names: Subcellular Location Annotation
messages: cytoskeleton

219594:PDGFB
gene id: 219594:PDGFB
uniprot id: A0A6J3EL26
names: Similarity
messages: Belongs to the PDGF/VEGF growth factor family.

219594:LTK
gene id: 219594:LTK
uniprot id: A0A6J3CXV6
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. Insulin receptor subfamily.

219594:BRINP3
gene id: 219594:BRINP3
uniprot id: A0A6J3DGQ2
names: Similarity
messages: Belongs to the BRINP family.

219594:CTLA4
gene id: 219594:CTLA4
uniprot id: A0A6J3D540
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Inhibitory receptor acting as a major negative regulator of T-cell responses. The affinity of CTLA4 for its natural B7 family ligands, CD80 and CD86, is considerably stronger than the affinity of their cognate stimulatory coreceptor CD28.
messages: Membrane

219594:DCP1B
gene id: 219594:DCP1B
uniprot id: A0A6J3D3R2
names: Similarity
messages: Belongs to the DCP1 family.

219594:IGF2BP2
gene id: 219594:IGF2BP2
uniprot id: A0A6J3DEY7
uniprot id: A0A6J3DIC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM IMP/VICKZ family.
messages: Cytoplasm

219594:AHR
gene id: 219594:AHR
uniprot id: A0A6J3CEB8
names: Subcellular Location Annotation
messages: Cytoplasm

219594:DCST1
gene id: 219594:DCST1
uniprot id: A0A6J3E8X6
names: Subcellular Location Annotation
messages: Membrane

219594:EXOC3L4
gene id: 219594:EXOC3L4
uniprot id: A0A6J3D2D4
names: Similarity
messages: Belongs to the SEC6 family.

219594:TSPAN7
gene id: 219594:TSPAN7
uniprot id: A0A6J3D720
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

219594:ANKLE2
gene id: 219594:ANKLE2
uniprot id: A0A6J3DT72
uniprot id: A0A6J3DXD1
names: Similarity
messages: Belongs to the ANKLE2 family.

219594:SLC1A2
gene id: 219594:SLC1A2
uniprot id: A0A6J3D5P3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

219594:LOC116500647
gene id: 219594:LOC116500647
uniprot id: A0A6J3EK70
names: Subcellular Location Annotation
messages: Chromosome

219594:LOC116487538
gene id: 219594:LOC116487538
uniprot id: A0A6J3CN10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. Very large inducible GTPase (VLIG) family.
messages: Nucleus

219594:PRDM8
gene id: 219594:PRDM8
uniprot id: A0A6J3D0H0
names: Subcellular Location Annotation
messages: Nucleus

219594:LOC116485699
gene id: 219594:LOC116485699
uniprot id: A0A6J3CI43
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c family.
messages: Membrane
messages: Mitochondrion inner membrane

219594:TARS3
gene id: 219594:TARS3
uniprot id: A0A6J3DHM9
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.

219594:S1PR2
gene id: 219594:S1PR2
uniprot id: A0A6J3EHM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

219594:TMEM138
gene id: 219594:TMEM138
uniprot id: A0A6J3D638
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM138 family.
messages: Membrane
messages: Required for ciliogenesis.
messages: Vacuole membrane
messages: cilium

219594:RMND1
gene id: 219594:RMND1
uniprot id: A0A6J3CR08
names: Similarity
messages: Belongs to the RMD1/sif2 family.

219594:SLC25A19
gene id: 219594:SLC25A19
uniprot id: A0A6J3DY08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

219594:FAM221A
gene id: 219594:FAM221A
uniprot id: A0A6J3CJ16
names: Similarity
messages: Belongs to the FAM221 family.

219594:EFHC2
gene id: 219594:EFHC2
uniprot id: A0A6J3EMB6
uniprot id: A0A6J3EMC8
names: Subcellular Location Annotation
messages: cilium axoneme

219594:UNC5C
gene id: 219594:UNC5C
uniprot id: A0A6J3CVZ5
uniprot id: A0A6J3CWD8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the unc-5 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for netrin required for axon guidance. Mediates axon repulsion of neuronal growth cones in the developing nervous system upon ligand binding.

219594:IL23A
gene id: 219594:IL23A
uniprot id: A0A6J3EA89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-6 superfamily.
messages: Secreted

219594:MTFR1
gene id: 219594:MTFR1
uniprot id: A0A6J3CFY6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MTFR1 family.
messages: Mitochondrion
messages: Plays a role in mitochondrial aerobic respiration. Regulates mitochondrial organization and fission.

219594:ANO1
gene id: 219594:ANO1
uniprot id: A0A6J3D0C9
uniprot id: A0A6J3D0D5
uniprot id: A0A6J3D2S8
uniprot id: A0A6J3D314
uniprot id: A0A6J3D5B4
uniprot id: A0A6J3D5C1
uniprot id: A0A6J3D696
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anoctamin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

219594:LOC116490337
gene id: 219594:LOC116490337
uniprot id: A0A6J3D4R0
names: Function
names: Similarity
messages: Belongs to the ferritin family.
messages: Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.

219594:MYO1D
gene id: 219594:MYO1D
uniprot id: A0A6J3EA21
uniprot id: A0A6J3EBH1
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

219594:SLC39A13
gene id: 219594:SLC39A13
uniprot id: A0A6J3D6S1
names: Subcellular Location Annotation
messages: Membrane

219594:RNF121
gene id: 219594:RNF121
uniprot id: A0A6J3E0P7
names: Subcellular Location Annotation
messages: Membrane

219594:RPL6
gene id: 219594:RPL6
uniprot id: A0A6J3DUY1
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL6 family.

219594:TXLNG
gene id: 219594:TXLNG
uniprot id: A0A6J3ENZ0
names: Similarity
messages: Belongs to the taxilin family.

219594:NKX1-2
gene id: 219594:NKX1-2
uniprot id: A0A6J3DCB7
names: Subcellular Location Annotation
messages: Nucleus

219594:MDGA2
gene id: 219594:MDGA2
uniprot id: A0A6J3CZF5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

219594:ABCC2
gene id: 219594:ABCC2
uniprot id: A0A6J3DCM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily.
messages: Cell membrane
messages: Early endosome membrane
messages: Endosome membrane
messages: Golgi apparatus membrane
messages: Late endosome membrane
messages: Lysosome membrane
messages: Melanosome membrane
messages: Membrane
messages: Mitochondrion outer membrane
messages: extracellular exosome
messages: multivesicular body membrane

219594:TP53RK
gene id: 219594:TP53RK
uniprot id: A0A6J3DXK6
names: Similarity
messages: Belongs to the protein kinase superfamily. BUD32 family.

219594:PRIMPOL
gene id: 219594:PRIMPOL
uniprot id: A0A6J3CXQ6
names: Similarity
messages: Belongs to the eukaryotic-type primase small subunit family.

219594:PSMA1
gene id: 219594:PSMA1
uniprot id: A0A6J3D6H5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essential roles within the cell by associating with different regulatory particles. Associated with two 19S regulatory particles, forms the 26S proteasome and thus participates in the ATP-dependent degradation of ubiquitinated proteins. The 26S proteasome plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins that could impair cellular functions, and by removing proteins whose functions are no longer required. Associated with the PA200 or PA28, the 20S proteasome mediates ubiquitin-independent protein degradation. This type of proteolysis is required in several pathways including spermatogenesis (20S-PA200 complex) or generation of a subset of MHC class I-presented antigenic peptides (20S-PA28 complex).
messages: Cytoplasm
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.

219594:GPT
gene id: 219594:GPT
uniprot id: A0A6J3CL53
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. Alanine aminotransferase subfamily.
messages: Homodimer.

219594:SSBP3
gene id: 219594:SSBP3
uniprot id: A0A6J3DCX7
uniprot id: A0A6J3DF54
names: Subcellular Location Annotation
messages: Nucleus

219594:METTL4
gene id: 219594:METTL4
uniprot id: A0A6J3CLK2
uniprot id: A0A6J3CPV3
names: Similarity
messages: Belongs to the MT-A70-like family.

219594:NUBP1
gene id: 219594:NUBP1
uniprot id: A0A6J3DVS4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP1/NBP35 subfamily.
messages: Binds 4 [4Fe-4S] clusters per heterotetramer. Contains two stable clusters in the N-termini of NUBP1 and two labile, bridging clusters between subunits of the NUBP1-NUBP2 heterotetramer.
messages: Cell projection
messages: Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NUBP1-NUBP2 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins.
messages: Cytoplasm
messages: Heterotetramer of 2 NUBP1 and 2 NUBP2 chains.

219594:LOC116498203
gene id: 219594:LOC116498203
uniprot id: A0A6J3EAE5
names: Similarity
messages: Belongs to the peptidase C1 family.

219594:TM4SF19
gene id: 219594:TM4SF19
uniprot id: A0A6J3DHX7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L6 tetraspanin family.
messages: Membrane

219594:LOC116485437
gene id: 219594:LOC116485437
uniprot id: A0A6J3CIL5
names: Similarity
names: Subunit
messages: Belongs to the avian keratin family.
messages: The avian keratins (F-ker, S-ker, C-ker and B-ker) are a complex mixture of very similar polypeptides.

219594:CPNE3
gene id: 219594:CPNE3
uniprot id: A0A6J3CE41
names: Similarity
messages: Belongs to the copine family.

219594:LOC116488194
gene id: 219594:LOC116488194
uniprot id: A0A6J3CW30
uniprot id: A0A6J3CX72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

219594:LNPEP
gene id: 219594:LNPEP
uniprot id: A0A6J3EDR4
names: Similarity
messages: Belongs to the peptidase M1 family.

219594:LOC116500816
gene id: 219594:LOC116500816
uniprot id: A0A6J3EIY1
names: Similarity
messages: Belongs to the cystatin family.

219594:PTGES3
gene id: 219594:PTGES3
uniprot id: A0A6J3EAN8
uniprot id: A0A6J3EFR1
names: Similarity
messages: Belongs to the p23/wos2 family.

219594:LOC116500460
gene id: 219594:LOC116500460
uniprot id: A0A6J3EJ58
names: Subcellular Location Annotation
messages: Membrane

219594:RBPJ
gene id: 219594:RBPJ
uniprot id: A0A6J3CU07
uniprot id: A0A6J3CWA0
uniprot id: A0A6J3CZ31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Su(H) family.
messages: Nucleus

219594:LOC116501290
gene id: 219594:LOC116501290
uniprot id: A0A6J3EHK6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:CDX1
gene id: 219594:CDX1
uniprot id: A0A6J3DNP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Caudal homeobox family.
messages: Nucleus

219594:LOC116500050
gene id: 219594:LOC116500050
uniprot id: A0A6J3EAX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

219594:PKP1
gene id: 219594:PKP1
uniprot id: A0A6J3E6F1
names: Similarity
messages: Belongs to the beta-catenin family.

219594:LPIN3
gene id: 219594:LPIN3
uniprot id: A0A6J3DUM4
names: Similarity
messages: Belongs to the lipin family.

219594:CCNDBP1
gene id: 219594:CCNDBP1
uniprot id: A0A6J3DWK0
names: Similarity
messages: Belongs to the CCNDBP1 family.

219594:VAMP7
gene id: 219594:VAMP7
uniprot id: A0A6J3DN79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Membrane

219594:DMRT1
gene id: 219594:DMRT1
uniprot id: A0A6J3EE53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DMRT family.
messages: Nucleus

219594:KAT7
gene id: 219594:KAT7
uniprot id: A0A6J3E4Z2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MYST (SAS/MOZ) family.
messages: Nucleus

219594:TP53I11
gene id: 219594:TP53I11
uniprot id: A0A6J3D0E7
names: Subcellular Location Annotation
messages: Membrane

219594:TUBGCP5
gene id: 219594:TUBGCP5
uniprot id: A0A6J3D8W1
uniprot id: A0A6J3DC42
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TUBGCP family.
messages: Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome.
messages: centrosome

219594:TUBB1
gene id: 219594:TUBB1
uniprot id: A0A6J3DYX8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
messages: cytoskeleton

219594:PSD2
gene id: 219594:PSD2
uniprot id: A0A6J3DQM3
uniprot id: A0A6J3DSN5
uniprot id: A0A6J3DUD2
names: Subcellular Location Annotation
messages: ruffle membrane

219594:APRT
gene id: 219594:APRT
uniprot id: A0A6J3DN64
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm

219594:SYT1
gene id: 219594:SYT1
uniprot id: A0A6J3CP00
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptotagmin family.
messages: Binds 3 Ca(2+) ions per subunit. The ions are bound to the C2 domains.
messages: May have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse. It binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone.
messages: Membrane
messages: chromaffin granule membrane
messages: synaptic vesicle membrane

219594:TYRP1
gene id: 219594:TYRP1
uniprot id: A0A6J3EJK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tyrosinase family.
messages: Melanosome membrane
messages: Membrane

219594:SSU72
gene id: 219594:SSU72
uniprot id: A0A6J3E166
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SSU72 phosphatase family.
messages: Nucleus
messages: Protein phosphatase that catalyzes the dephosphorylation of the C-terminal domain of RNA polymerase II. Plays a role in RNA processing and termination.

219594:AGPAT3
gene id: 219594:AGPAT3
uniprot id: A0A6J3CXJ6
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

219594:ARSJ
gene id: 219594:ARSJ
uniprot id: A0A6J3CUM4
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

219594:MAFB
gene id: 219594:MAFB
uniprot id: A0A6J3DUX1
names: Similarity
messages: Belongs to the bZIP family. Maf subfamily.

219594:LOC116494698
gene id: 219594:LOC116494698
uniprot id: A0A6J3DSF2
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

219594:CTNNAL1
gene id: 219594:CTNNAL1
uniprot id: A0A6J3CKR9
names: Similarity
messages: Belongs to the vinculin/alpha-catenin family.

219594:LGI3
gene id: 219594:LGI3
uniprot id: A0A6J3E8J5
names: Subcellular Location Annotation
messages: Secreted

219594:LOC116497351
gene id: 219594:LOC116497351
uniprot id: A0A6J3E013
uniprot id: A0A6J3E525
names: Subcellular Location Annotation
messages: Membrane

219594:LOC116500192
gene id: 219594:LOC116500192
uniprot id: A0A6J3EBF7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

219594:EXOC8
gene id: 219594:EXOC8
uniprot id: A0A6J3CQ56
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EXO84 family.
messages: Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.
messages: growth cone
messages: perinuclear region

219594:ZFYVE9
gene id: 219594:ZFYVE9
uniprot id: A0A6J3DGM7
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Early endosome membrane

219594:C26H19orf25
gene id: 219594:C26H19orf25
uniprot id: A0A6J3EDI5
names: Similarity
messages: Belongs to the UPF0449 family.

219594:DIPK1A
gene id: 219594:DIPK1A
uniprot id: A0A6J3DAJ8
uniprot id: A0A6J3DG89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DIPK family.
messages: Endoplasmic reticulum membrane

219594:MPP4
gene id: 219594:MPP4
uniprot id: A0A6J3D3F7
names: Similarity
messages: Belongs to the MAGUK family.

219594:VWC2L
gene id: 219594:VWC2L
uniprot id: A0A6J3D3Q2
uniprot id: A0A6J3D6A7
uniprot id: A0A6J3D6S8
names: Subcellular Location Annotation
messages: Synapse

219594:LOC116497033
gene id: 219594:LOC116497033
uniprot id: A0A6J3E2Q5
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

219594:CPT2
gene id: 219594:CPT2
uniprot id: A0A6J3DBQ3
names: Similarity
messages: Belongs to the carnitine/choline acetyltransferase family.

219594:LDHB
gene id: 219594:LDHB
uniprot id: A0A6J3EI48
names: Similarity
messages: Belongs to the LDH/MDH superfamily. LDH family.

219594:BET1L
gene id: 219594:BET1L
uniprot id: A0A6J3D2W8
names: Subcellular Location Annotation
messages: Membrane

219594:LOC116487341
gene id: 219594:LOC116487341
uniprot id: A0A6J3CS00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the natriuretic peptide family.
messages: Secreted

219594:ADRM1
gene id: 219594:ADRM1
uniprot id: A0A6J3DUJ7
uniprot id: A0A6J3DWT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADRM1 family.
messages: Cytoplasm
messages: Nucleus

219594:TMEM255B
gene id: 219594:TMEM255B
uniprot id: A0A6J3E4P4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM255 family.
messages: Membrane

219594:NTNG1
gene id: 219594:NTNG1
uniprot id: A0A6J3D8E8
uniprot id: A0A6J3DB53
uniprot id: A0A6J3DC03
uniprot id: A0A6J3DE42
uniprot id: A0A6J3DEE0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:ALB
gene id: 219594:ALB
uniprot id: A0A6J3D0U0
names: Subcellular Location Annotation
messages: Secreted

219594:POLR1B
gene id: 219594:POLR1B
uniprot id: A0A6J3CPT4
names: Function
names: Similarity
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Second largest core component of RNA polymerase I which synthesizes ribosomal RNA precursors. Proposed to contribute to the polymerase catalytic activity and forms the polymerase active center together with the largest subunit. Pol I is composed of mobile elements and RPA2 is part of the core element with the central large cleft and probably a clamp element that moves to open and close the cleft.

219594:ATP4B
gene id: 219594:ATP4B
uniprot id: A0A6J3EQS7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the X(+)/potassium ATPases subunit beta family.
messages: Membrane
messages: This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane.

219594:LOC116499494
gene id: 219594:LOC116499494
uniprot id: A0A6J3EDL1
names: Similarity
names: Subunit
messages: Belongs to the avian keratin family.
messages: The avian keratins (F-ker, S-ker, C-ker and B-ker) are a complex mixture of very similar polypeptides.

219594:MINAR2
gene id: 219594:MINAR2
uniprot id: A0A6J3EDC0
names: Similarity
messages: Belongs to the MINAR family.

219594:CSK
gene id: 219594:CSK
uniprot id: A0A6J3DMX7
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

219594:SELP
gene id: 219594:SELP
uniprot id: A0A6J3DFK3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the selectin/LECAM family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

219594:FGF4
gene id: 219594:FGF4
uniprot id: A0A6J3D781
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heparin-binding growth factors family.
messages: Secreted

219594:ADGRL4
gene id: 219594:ADGRL4
uniprot id: A0A6J3DD90
uniprot id: A0A6J3DEB4
uniprot id: A0A6J3DGG4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

219594:LOC116499193
gene id: 219594:LOC116499193
uniprot id: A0A6J3E7T1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complexin/synaphin family.
messages: Synapse

219594:CAT
gene id: 219594:CAT
uniprot id: A0A6J3D1D1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the catalase family.
messages: Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.
messages: Peroxisome

219594:CDK5R2
gene id: 219594:CDK5R2
uniprot id: A0A6J3D6X6
names: Similarity
names: Subunit
messages: Belongs to the cyclin-dependent kinase 5 activator family.
messages: Heterodimer of a catalytic subunit and a regulatory subunit.

219594:SLC4A5
gene id: 219594:SLC4A5
uniprot id: A0A6J3E8G8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anion exchanger (TC 2.A.31) family.
messages: Membrane

219594:TUT4
gene id: 219594:TUT4
uniprot id: A0A6J3D957
uniprot id: A0A6J3DCT6
uniprot id: A0A6J3DF19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-B-like family.
messages: Cytoplasm

219594:RSRP1
gene id: 219594:RSRP1
uniprot id: A0A6J3E9D5
names: Similarity
messages: Belongs to the RSRP family.

219594:ADSL
gene id: 219594:ADSL
uniprot id: A0A6J3DCL5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
messages: Catalyzes two non-sequential steps in de novo AMP synthesis: converts (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate (SAICAR) to fumarate plus 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide, and thereby also contributes to de novo IMP synthesis, and converts succinyladenosine monophosphate (SAMP) to AMP and fumarate.
messages: Homotetramer. Residues from neighboring subunits contribute catalytic and substrate-binding residues to each active site.

219594:PIF1
gene id: 219594:PIF1
uniprot id: A0A6J3DGT2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the helicase family. PIF1 subfamily.
messages: DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mitochondrion
messages: Monomer.
messages: Nucleus

219594:DBNDD2
gene id: 219594:DBNDD2
uniprot id: A0A6J3DYB1
names: Similarity
messages: Belongs to the dysbindin family.

219594:STXBP3
gene id: 219594:STXBP3
uniprot id: A0A6J3DCV4
names: Similarity
messages: Belongs to the STXBP/unc-18/SEC1 family.

219594:PMM2
gene id: 219594:PMM2
uniprot id: A0A6J3DTV6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic PMM family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions.

219594:LOC116494597
gene id: 219594:LOC116494597
uniprot id: A0A6J3DP57
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTR/RAG GTP-binding protein family.
messages: Cytoplasm
messages: Guanine nucleotide-binding protein that plays a crucial role in the cellular response to amino acid availability through regulation of the mTORC1 signaling cascade.
messages: Lysosome

219594:LOC116488574
gene id: 219594:LOC116488574
uniprot id: A0A6J3CV13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: tight junction

219594:ND5
gene id: 219594:ND5
uniprot id: A0A068LAU4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 5 family.
messages: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I.
messages: Membrane
messages: Mitochondrion inner membrane

219594:LOC116501457
gene id: 219594:LOC116501457
uniprot id: A0A6J3ENF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GOLPH3/VPS74 family.
messages: Golgi stack membrane
messages: Membrane
messages: trans-Golgi network membrane

219594:NAAA
gene id: 219594:NAAA
uniprot id: A0A6J3CV03
names: Similarity
messages: Belongs to the acid ceramidase family.

219594:FAM189B
gene id: 219594:FAM189B
uniprot id: A0A6J3EBD7
uniprot id: A0A6J3EGQ9
names: Similarity
messages: Belongs to the ENTREP family.

219594:NPBWR2
gene id: 219594:NPBWR2
uniprot id: A0A6J3DS08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:IMMP1L
gene id: 219594:IMMP1L
uniprot id: A0A6J3D763
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S26 family.
messages: Heterodimer of 2 subunits, IMMPL1 and IMMPL2.
messages: Mitochondrion inner membrane

219594:ZIC2
gene id: 219594:ZIC2
uniprot id: A0A6J3DQ83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GLI C2H2-type zinc-finger protein family.
messages: Nucleus

219594:FIGNL1
gene id: 219594:FIGNL1
uniprot id: A0A6J3CKN0
names: Similarity
messages: Belongs to the AAA ATPase family.

219594:STS
gene id: 219594:STS
uniprot id: A0A6J3CLN8
uniprot id: A0A6J3CLP4
uniprot id: A0A6J3CR50
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

219594:MDFIC
gene id: 219594:MDFIC
uniprot id: A0A6J3DL14
names: Similarity
messages: Belongs to the MDFI family.

219594:RANBP10
gene id: 219594:RANBP10
uniprot id: A0A6J3DIL9
uniprot id: A0A6J3DMQ9
names: Similarity
messages: Belongs to the RANBP9/10 family.

219594:FAM102B
gene id: 219594:FAM102B
uniprot id: A0A6J3DF06
names: Similarity
messages: Belongs to the FAM102 family.

219594:SORCS2
gene id: 219594:SORCS2
uniprot id: A0A6J3CTU0
uniprot id: A0A6J3CW37
uniprot id: A0A6J3CYV7
uniprot id: A0A6J3CYW2
uniprot id: A0A6J3CZW5
uniprot id: A0A6J3CZX0
names: Similarity
messages: Belongs to the VPS10-related sortilin family. SORCS subfamily.

219594:INTU
gene id: 219594:INTU
uniprot id: A0A6J3CZ32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inturned family.
messages: Cell surface
messages: cilium basal body

219594:RAD50
gene id: 219594:RAD50
uniprot id: A0A6J3DSU1
names: Similarity
messages: Belongs to the SMC family. RAD50 subfamily.

219594:BEND5
gene id: 219594:BEND5
uniprot id: A0A6J3DBH4
uniprot id: A0A6J3DCC7
uniprot id: A0A6J3DEF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M14 family.
messages: cytosol

219594:EPHB1
gene id: 219594:EPHB1
uniprot id: A0A6J3DIT4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: dendrite

219594:DEUP1
gene id: 219594:DEUP1
uniprot id: A0A6J3EPZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CEP63 family.
messages: Cytoplasm

219594:COX3
gene id: 219594:COX3
uniprot id: A0A068L8T9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
messages: Membrane

219594:GRB7
gene id: 219594:GRB7
uniprot id: A0A6J3EA06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GRB7/10/14 family.
messages: Cytoplasm

219594:CHRNG
gene id: 219594:CHRNG
uniprot id: A0A6J3DIJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

219594:ADAM19
gene id: 219594:ADAM19
uniprot id: A0A6J3DS34
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:RPS6KB2
gene id: 219594:RPS6KB2
uniprot id: A0A6J3D1H2
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.

219594:PAFAH1B1
gene id: 219594:PAFAH1B1
uniprot id: A0A6J3E022
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat LIS1/nudF family.
messages: Can self-associate. Interacts with dynein, dynactin, NDE1 and NDEL1.
messages: Dimerization mediated by the LisH domain may be required to activate dynein.
messages: Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. May be required for proliferation of neuronal precursors and neuronal migration.
messages: centrosome
messages: cytoskeleton

219594:TBX10
gene id: 219594:TBX10
uniprot id: A0A6J3D3N4
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

219594:LOC116497198
gene id: 219594:LOC116497198
uniprot id: A0A6J3E4E4
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

219594:CD151
gene id: 219594:CD151
uniprot id: A0A6J3CZT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

219594:PNPLA6
gene id: 219594:PNPLA6
uniprot id: A0A6J3EFR2
uniprot id: A0A6J3EG14
uniprot id: A0A6J3EHN7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NTE family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

219594:LOC116490057
gene id: 219594:LOC116490057
uniprot id: A0A6J3D6E9
names: Similarity
messages: Belongs to the serpin family.

219594:ST3GAL3
gene id: 219594:ST3GAL3
uniprot id: A0A6J3DAR0
uniprot id: A0A6J3DDB9
uniprot id: A0A6J3DEE4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

219594:LOC116498570
gene id: 219594:LOC116498570
uniprot id: A0A6J3E9L3
names: Similarity
names: Subunit
messages: Belongs to the avian keratin family.
messages: The avian keratins (F-ker, S-ker, C-ker and B-ker) are a complex mixture of very similar polypeptides.

219594:KIN
gene id: 219594:KIN
uniprot id: A0A6J3EIJ4
uniprot id: A0A6J3ENR9
names: Similarity
messages: Belongs to the KIN17 family.

219594:LOC116491301
gene id: 219594:LOC116491301
uniprot id: A0A6J3D6K6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:TMEM244
gene id: 219594:TMEM244
uniprot id: A0A6J3CQH3
names: Subcellular Location Annotation
messages: Membrane

219594:TGFB3
gene id: 219594:TGFB3
uniprot id: A0A6J3D710
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TGF-beta family.
messages: Transforming growth factor beta-3 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-3 (TGF-beta-3) chains, which constitute the regulatory and active subunit of TGF-beta-3, respectively.
messages: extracellular matrix

219594:EME1
gene id: 219594:EME1
uniprot id: A0A6J3DYK3
names: Similarity
messages: Belongs to the EME1/MMS4 family.

219594:ENPP1
gene id: 219594:ENPP1
uniprot id: A0A6J3CMW0
names: Subcellular Location Annotation
messages: Secreted

219594:FAM229A
gene id: 219594:FAM229A
uniprot id: A0A6J3E301
names: Similarity
messages: Belongs to the FAM229 family.

219594:LOC116489490
gene id: 219594:LOC116489490
uniprot id: A0A6J3D3L3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:NHSL1
gene id: 219594:NHSL1
uniprot id: A0A6J3CMC6
uniprot id: A0A6J3CP67
uniprot id: A0A6J3CQ06
uniprot id: A0A6J3CSB2
uniprot id: A0A6J3CTE6
names: Similarity
messages: Belongs to the NHS family.

219594:SLC6A11
gene id: 219594:SLC6A11
uniprot id: A0A6J3DIQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

219594:WNT3A
gene id: 219594:WNT3A
uniprot id: A0A6J3CJ03
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

219594:CORO7
gene id: 219594:CORO7
uniprot id: A0A6J3DUY5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat coronin family.
messages: Cytoplasmic vesicle
messages: F-actin regulator involved in anterograde Golgi to endosome transport: upon ubiquitination via 'Lys-33'-linked ubiquitin chains by the BCR(KLHL20) E3 ubiquitin ligase complex, interacts with EPS15 and localizes to the trans-Golgi network, where it promotes actin polymerization, thereby facilitating post-Golgi trafficking. May play a role in the maintenance of the Golgi apparatus morphology.
messages: Golgi apparatus membrane
messages: Membrane
messages: Vesicle
messages: cytosol
messages: trans-Golgi network

219594:RGS7BP
gene id: 219594:RGS7BP
uniprot id: A0A6J3EEA0
uniprot id: A0A6J3EHS7
uniprot id: A0A6J3EJQ2
names: Similarity
messages: Belongs to the RGS7BP/RGS9BP family.

219594:CRYBB3
gene id: 219594:CRYBB3
uniprot id: A0A6J3DXB3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the beta/gamma-crystallin family.
messages: Crystallins are the dominant structural components of the vertebrate eye lens.
messages: Homo/heterodimer, or complexes of higher-order. The structure of beta-crystallin oligomers seems to be stabilized through interactions between the N-terminal arms.

219594:LOC116501365
gene id: 219594:LOC116501365
uniprot id: A0A6J3EGA7
names: Subcellular Location Annotation
messages: Membrane

219594:ADCY9
gene id: 219594:ADCY9
uniprot id: A0A6J3DRT5
names: Similarity
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.

219594:DMTN
gene id: 219594:DMTN
uniprot id: A0A6J3EDT9
names: Subcellular Location Annotation
messages: Cytoplasm

219594:CNKSR1
gene id: 219594:CNKSR1
uniprot id: A0A6J3E8Z5
names: Similarity
messages: Belongs to the CNKSR family.

219594:WFIKKN2
gene id: 219594:WFIKKN2
uniprot id: A0A6J3E2M4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WFIKKN family.
messages: Secreted

219594:WT1
gene id: 219594:WT1
uniprot id: A0A6J3D189
uniprot id: A0A6J3D727
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EGR C2H2-type zinc-finger protein family.
messages: Cytoplasm
messages: Nucleus speckle

219594:NUP98
gene id: 219594:NUP98
uniprot id: A0A6J3DZ44
uniprot id: A0A6J3E1H4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleoporin GLFG family.
messages: Nucleus membrane
messages: nuclear pore complex

219594:CDK2AP2
gene id: 219594:CDK2AP2
uniprot id: A0A6J3D3J1
names: Similarity
messages: Belongs to the CDK2AP family.

219594:GGH
gene id: 219594:GGH
uniprot id: A0A6J3CDQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C26 family.
messages: extracellular space

219594:OST4
gene id: 219594:OST4
uniprot id: A0A6J3CVK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OST4 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

219594:KCNG4
gene id: 219594:KCNG4
uniprot id: A0A6J3DQH6
names: Subcellular Location Annotation
messages: Membrane

219594:MRPL9
gene id: 219594:MRPL9
uniprot id: A0A6J3EG89
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.

219594:CNN3
gene id: 219594:CNN3
uniprot id: A0A6J3DFG0
names: Function
names: Similarity
messages: Belongs to the calponin family.
messages: Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity.

219594:FAM124A
gene id: 219594:FAM124A
uniprot id: A0A6J3EIY6
uniprot id: A0A6J3EPA0
names: Similarity
messages: Belongs to the FAM124 family.

219594:REM1
gene id: 219594:REM1
uniprot id: A0A6J3DYG7
names: Similarity
messages: Belongs to the small GTPase superfamily. RGK family.

219594:PTGER3
gene id: 219594:PTGER3
uniprot id: A0A6J3DDV2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

219594:LOC116497489
gene id: 219594:LOC116497489
uniprot id: A0A6J3E1Y2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase A2 family.
messages: Binds 1 Ca(2+) ion per subunit.
messages: Secreted

219594:SERPINE2
gene id: 219594:SERPINE2
uniprot id: A0A6J3DCM6
uniprot id: A0A6J3DGJ0
uniprot id: A0A6J3DI66
names: Similarity
messages: Belongs to the serpin family.

219594:LOC116502202
gene id: 219594:LOC116502202
uniprot id: A0A6J3ER66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:PRICKLE1
gene id: 219594:PRICKLE1
uniprot id: A0A6J3DY05
names: Similarity
messages: Belongs to the prickle / espinas / testin family.

219594:MEP1B
gene id: 219594:MEP1B
uniprot id: A0A6J3CG24
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

219594:SNX4
gene id: 219594:SNX4
uniprot id: A0A6J3D911
names: Similarity
messages: Belongs to the sorting nexin family.

219594:BCCIP
gene id: 219594:BCCIP
uniprot id: A0A6J3DBJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BCP1 family.
messages: spindle pole

219594:CLUH
gene id: 219594:CLUH
uniprot id: A0A6J3DYZ2
uniprot id: A0A6J3E382
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CLU family.
messages: Cytoplasm
messages: Cytoplasmic granule
messages: mRNA-binding protein involved in proper cytoplasmic distribution of mitochondria. Specifically binds mRNAs of nuclear-encoded mitochondrial proteins in the cytoplasm and regulates transport or translation of these transcripts close to mitochondria, playing a role in mitochondrial biogenesis.

219594:ACSL6
gene id: 219594:ACSL6
uniprot id: A0A6J3DNN2
uniprot id: A0A6J3DQY5
uniprot id: A0A6J3DSZ3
uniprot id: A0A6J3DTV4
names: Function
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of long-chain fatty acids to their active form acyl-CoAs for both synthesis of cellular lipids, and degradation via beta-oxidation.

219594:OSBPL8
gene id: 219594:OSBPL8
uniprot id: A0A6J3EJL2
uniprot id: A0A6J3ENG1
uniprot id: A0A6J3ENH4
uniprot id: A0A6J3EPX7
names: Similarity
messages: Belongs to the OSBP family.

219594:SLC30A8
gene id: 219594:SLC30A8
uniprot id: A0A6J3CL49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
messages: Cell membrane
messages: Membrane
messages: secretory vesicle membrane

219594:MTUS1
gene id: 219594:MTUS1
uniprot id: A0A6J3CV11
uniprot id: A0A6J3CXC2
uniprot id: A0A6J3D011
uniprot id: A0A6J3D155
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MTUS1 family.
messages: Nucleus

219594:MED24
gene id: 219594:MED24
uniprot id: A0A6J3EBW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mediator complex subunit 24 family.
messages: Nucleus

219594:FAM53A
gene id: 219594:FAM53A
uniprot id: A0A6J3CTM2
uniprot id: A0A6J3CVX9
names: Similarity
messages: Belongs to the FAM53 family.

219594:SHANK3
gene id: 219594:SHANK3
uniprot id: A0A6J3DSZ6
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Postsynaptic density

219594:COLGALT2
gene id: 219594:COLGALT2
uniprot id: A0A6J3DA32
names: Similarity
messages: Belongs to the glycosyltransferase 25 family.

219594:SPOCK2
gene id: 219594:SPOCK2
uniprot id: A0A6J3D918
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

219594:WASL
gene id: 219594:WASL
uniprot id: A0A6J3D128
names: Subcellular Location Annotation
messages: Nucleus

219594:LOC116494038
gene id: 219594:LOC116494038
uniprot id: A0A6J3DJK0
uniprot id: A0A6J3DQN3
names: Subcellular Location Annotation
messages: Membrane

219594:MRPL47
gene id: 219594:MRPL47
uniprot id: A0A6J3DCZ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal ribosomal protein uL29 family.
messages: Mitochondrion

219594:FABP7
gene id: 219594:FABP7
uniprot id: A0A6J3CNF3
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

219594:MTR
gene id: 219594:MTR
uniprot id: A0A6J3CPK2
uniprot id: A0A6J3CRL6
uniprot id: A0A6J3CVN1
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methylcob(III)alamin (MeCbl) to homocysteine, yielding enzyme-bound cob(I)alamin and methionine in the cytosol. MeCbl is an active form of cobalamin (vitamin B12) used as a cofactor for methionine biosynthesis. Cob(I)alamin form is regenerated to MeCbl by a transfer of a methyl group from 5-methyltetrahydrofolate. The processing of cobalamin in the cytosol occurs in a multiprotein complex composed of at least MMACHC, MMADHC, MTRR (methionine synthase reductase) and MTR which may contribute to shuttle safely and efficiently cobalamin towards MTR in order to produce methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.

219594:ADPRM
gene id: 219594:ADPRM
uniprot id: A0A6J3DYI2
names: Similarity
names: Subunit
messages: Belongs to the ADPRibase-Mn family.
messages: Monomer.

219594:LOC116492240
gene id: 219594:LOC116492240
uniprot id: A0A6J3DDX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the spire family.
messages: Cell membrane
messages: Cytoplasmic vesicle membrane
messages: Membrane
messages: cytoskeleton

219594:PTPRM
gene id: 219594:PTPRM
uniprot id: A0A6J3CDW3
uniprot id: A0A6J3CDW7
uniprot id: A0A6J3CFI3
uniprot id: A0A6J3CFJ3
uniprot id: A0A6J3CGI4
uniprot id: A0A6J3CGI9
uniprot id: A0A6J3CIE5
uniprot id: A0A6J3CIF1
uniprot id: A0A6J3CK36
uniprot id: A0A6J3CK42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Receptor class 2B subfamily.
messages: Membrane

219594:FAR1
gene id: 219594:FAR1
uniprot id: A0A6J3CXG4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acyl-CoA reductase family.
messages: Catalyzes the reduction of fatty acyl-CoA to fatty alcohols.
messages: Peroxisome membrane

219594:LOC116494673
gene id: 219594:LOC116494673
uniprot id: A0A6J3DM49
uniprot id: A0A6J3DPG3
uniprot id: A0A6J3DRG7
uniprot id: A0A6J3DRH2
uniprot id: A0A6J3DSA8
uniprot id: A0A6J3DTE4
names: Subcellular Location Annotation
messages: Cytoplasm

219594:OBSCN
gene id: 219594:OBSCN
uniprot id: A0A6J3CML2
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.

219594:SETD7
gene id: 219594:SETD7
uniprot id: A0A6J3CXE3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SET7 subfamily.
messages: Chromosome
messages: Histone methyltransferase that specifically monomethylates 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. Plays a central role in the transcriptional activation of genes.
messages: Nucleus

219594:LOC116492307
gene id: 219594:LOC116492307
uniprot id: A0A6J3DBE8
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

219594:HSD17B12
gene id: 219594:HSD17B12
uniprot id: A0A6J3D192
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

219594:BTF3
gene id: 219594:BTF3
uniprot id: A0A6J3EI22
names: Similarity
messages: Belongs to the NAC-beta family.

219594:SAMD8
gene id: 219594:SAMD8
uniprot id: A0A6J3DC51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sphingomyelin synthase family.
messages: Membrane

219594:VIPR1
gene id: 219594:VIPR1
uniprot id: A0A6J3CQM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family.
messages: Cell membrane
messages: Membrane

219594:PDCD4
gene id: 219594:PDCD4
uniprot id: A0A6J3DCU1
names: Similarity
messages: Belongs to the PDCD4 family.

219594:EHD3
gene id: 219594:EHD3
uniprot id: A0A6J3CPI0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Endosome membrane
messages: Membrane
messages: Recycling endosome membrane
messages: cilium membrane

219594:EIF3D
gene id: 219594:EIF3D
uniprot id: A0A6J3EHU0
uniprot id: A0A6J3EN21
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit D family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M.
messages: Cytoplasm
messages: The RNA gate region regulates mRNA cap recognition to prevent promiscuous mRNA-binding before assembly of eif3d into the full eukaryotic translation initiation factor 3 (eIF-3) complex.
messages: mRNA cap-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. In the eIF-3 complex, eif3d specifically recognizes and binds the 7-methylguanosine cap of a subset of mRNAs.

219594:TRARG1
gene id: 219594:TRARG1
uniprot id: A0A6J3E3U7
uniprot id: A0A6J3E4V1
names: Similarity
messages: Belongs to the CD225/Dispanin family.

219594:LOC116489554
gene id: 219594:LOC116489554
uniprot id: A0A6J3D3T7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COX16 family.
messages: Membrane

219594:NSG1
gene id: 219594:NSG1
uniprot id: A0A6J3CXS6
names: Similarity
messages: Belongs to the NSG family.

219594:SMIM15
gene id: 219594:SMIM15
uniprot id: A0A6J3ED74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMIM15 family.
messages: Membrane

219594:HDAC2
gene id: 219594:HDAC2
uniprot id: A0A6J3CRK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone deacetylase family. HD Type 1 subfamily.
messages: Nucleus

219594:SLC6A1
gene id: 219594:SLC6A1
uniprot id: A0A6J3DE60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

219594:CDIP1
gene id: 219594:CDIP1
uniprot id: A0A6J3DTX2
uniprot id: A0A6J3DVP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDIP1/LITAF family.
messages: Lysosome membrane
messages: Membrane

219594:DUOXA2
gene id: 219594:DUOXA2
uniprot id: A0A6J3DKK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DUOXA family.
messages: Membrane

219594:FAM162A
gene id: 219594:FAM162A
uniprot id: A0A6J3DCU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0389 family.
messages: Membrane

219594:SLC25A37
gene id: 219594:SLC25A37
uniprot id: A0A6J3EDR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

219594:LOC116498258
gene id: 219594:LOC116498258
uniprot id: A0A6J3E8G0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the COQ10 family.
messages: Interacts with coenzyme Q.
messages: Required for the function of coenzyme Q in the respiratory chain. May serve as a chaperone or may be involved in the transport of Q6 from its site of synthesis to the catalytic sites of the respiratory complexes.

219594:NCBP1
gene id: 219594:NCBP1
uniprot id: A0A6J3EHT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NCBP1 family.
messages: Nucleus

219594:LOC116493530
gene id: 219594:LOC116493530
uniprot id: A0A6J3DNI0
names: Similarity
messages: Belongs to the intermediate filament family.

219594:INTS11
gene id: 219594:INTS11
uniprot id: A0A6J3E238
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. INTS11 subfamily.
messages: Nucleus

219594:RPL21
gene id: 219594:RPL21
uniprot id: A0A6J3EI16
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL21 family.

219594:DNM1
gene id: 219594:DNM1
uniprot id: A0A6J3DYJ3
uniprot id: A0A6J3E078
uniprot id: A0A6J3E081
uniprot id: A0A6J3E2T7
uniprot id: A0A6J3E2U3
uniprot id: A0A6J3E3L0
uniprot id: A0A6J3E3L7
uniprot id: A0A6J3E3M3
uniprot id: A0A6J3E4L9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.
messages: cytoskeleton

219594:DYNLT1
gene id: 219594:DYNLT1
uniprot id: A0A6J3CQJ0
names: Similarity
messages: Belongs to the dynein light chain Tctex-type family.

219594:CHMP7
gene id: 219594:CHMP7
uniprot id: A0A6J3E8N0
names: Similarity
messages: Belongs to the SNF7 family.

219594:DLX3
gene id: 219594:DLX3
uniprot id: A0A6J3EAD3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the distal-less homeobox family.
messages: Nucleus

219594:LOC116489984
gene id: 219594:LOC116489984
uniprot id: A0A6J3D068
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

219594:PRPF3
gene id: 219594:PRPF3
uniprot id: A0A6J3EEF9
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex).

219594:MNS1
gene id: 219594:MNS1
uniprot id: A0A6J3DJW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MNS1 family.
messages: Nucleus
messages: cilium axoneme
messages: flagellum axoneme

219594:SLC39A14
gene id: 219594:SLC39A14
uniprot id: A0A6J3E887
names: Subcellular Location Annotation
messages: Membrane

219594:TERF2IP
gene id: 219594:TERF2IP
uniprot id: A0A6J3DPM5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts both as a regulator of telomere function and as a transcription regulator. Involved in the regulation of telomere length and protection as a component of the shelterin complex (telosome). Does not bind DNA directly: recruited to telomeric double-stranded 5'-TTAGGG-3' repeats via its interaction with terf2. Independently of its function in telomeres, also acts as a transcription regulator: recruited to extratelomeric 5'-TTAGGG-3' sites via its association with terf2 or other factors, and regulates gene expression.
messages: Belongs to the RAP1 family.
messages: Homodimer.
messages: Nucleus
messages: telomere

219594:LOC116500210
gene id: 219594:LOC116500210
uniprot id: A0A6J3EG56
names: Subcellular Location Annotation
messages: extracellular matrix

219594:OCRL
gene id: 219594:OCRL
uniprot id: A0A6J3DNX7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inositol 1,4,5-trisphosphate 5-phosphatase type II family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Membrane
messages: phagosome membrane

219594:CENPL
gene id: 219594:CENPL
uniprot id: A0A6J3DDD7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CENP-L/IML3 family.
messages: Nucleus

219594:ITPKB
gene id: 219594:ITPKB
uniprot id: A0A6J3CQD9
names: Similarity
messages: Belongs to the inositol phosphokinase (IPK) family.

219594:RAD9A
gene id: 219594:RAD9A
uniprot id: A0A6J3D4B0
names: Similarity
messages: Belongs to the rad9 family.

219594:TMEM123
gene id: 219594:TMEM123
uniprot id: A0A6J3D7H5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CD164 family.
messages: Membrane

219594:DIMT1
gene id: 219594:DIMT1
uniprot id: A0A6J3EDD0
uniprot id: A0A6J3EII8
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:LOC116499015
gene id: 219594:LOC116499015
uniprot id: A0A6J3EDS5
names: Similarity
messages: Belongs to the peptidase C1 family.

219594:FAM171A1
gene id: 219594:FAM171A1
uniprot id: A0A6J3CDX7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM171 family.
messages: Membrane

219594:SMARCAL1
gene id: 219594:SMARCAL1
uniprot id: A0A6J3D7I4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF2/RAD54 helicase family. SMARCAL1 subfamily.
messages: Nucleus

219594:RBM48
gene id: 219594:RBM48
uniprot id: A0A6J3CI59
names: Similarity
messages: Belongs to the RBM48 family.

219594:GSDMA
gene id: 219594:GSDMA
uniprot id: A0A6J3EB64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gasdermin family.
messages: Cell membrane
messages: Membrane

219594:PPTC7
gene id: 219594:PPTC7
uniprot id: A0A6J3DYB3
names: Similarity
messages: Belongs to the PP2C family.

219594:NDC1
gene id: 219594:NDC1
uniprot id: A0A6J3DFE4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NDC1 family.
messages: Component of the nuclear pore complex (NPC), which plays a key role in de novo assembly and insertion of NPC in the nuclear envelope. Required for NPC and nuclear envelope assembly, possibly by forming a link between the nuclear envelope membrane and soluble nucleoporins, thereby anchoring the NPC in the membrane.
messages: Membrane
messages: Nucleus membrane
messages: nuclear pore complex

219594:MINDY3
gene id: 219594:MINDY3
uniprot id: A0A6J3CFP3
names: Function
names: Similarity
messages: Belongs to the MINDY deubiquitinase family. FAM188 subfamily.
messages: Hydrolase that can remove 'Lys-48'-linked conjugated ubiquitin from proteins.

219594:RAB33A
gene id: 219594:RAB33A
uniprot id: A0A6J3DRX7
names: Similarity
messages: Belongs to the small GTPase superfamily. Rab family.

219594:ATP6V1D
gene id: 219594:ATP6V1D
uniprot id: A0A6J3D428
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase D subunit family.
messages: clathrin-coated vesicle membrane

219594:MDM1
gene id: 219594:MDM1
uniprot id: A0A6J3EIP0
uniprot id: A0A6J3ENT1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MDM1 family.
messages: Nucleus
messages: centriole

219594:LOC116500316
gene id: 219594:LOC116500316
uniprot id: A0A6J3EBS1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:PLPPR4
gene id: 219594:PLPPR4
uniprot id: A0A6J3DDI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Membrane

219594:TADA3
gene id: 219594:TADA3
uniprot id: A0A6J3DKU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NGG1 family.
messages: Nucleus

219594:SMC3
gene id: 219594:SMC3
uniprot id: A0A6J3DC55
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMC family. SMC3 subfamily.
messages: Central component of cohesin, a complex required for chromosome cohesion during the cell cycle. The cohesin complex may form a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate. Cohesion is coupled to DNA replication and is involved in DNA repair. The cohesin complex also plays an important role in spindle pole assembly during mitosis and in chromosomes movement.
messages: Nucleus
messages: centromere

219594:LOC116489131
gene id: 219594:LOC116489131
uniprot id: A0A6J3D1S2
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.

219594:NKX2-2
gene id: 219594:NKX2-2
uniprot id: A0A6J3CVR1
names: Subcellular Location Annotation
messages: Nucleus

219594:SARAF
gene id: 219594:SARAF
uniprot id: A0A6J3CVP1
uniprot id: A0A6J3CXZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SARAF family.
messages: Endoplasmic reticulum membrane
messages: Membrane

219594:THG1L
gene id: 219594:THG1L
uniprot id: A0A6J3DTG9
names: Cofactor
names: Function
names: Similarity
messages: Adds a GMP to the 5'-end of tRNA(His) after transcription and RNase P cleavage.
messages: Belongs to the tRNA(His) guanylyltransferase family.
messages: Binds 2 magnesium ions per subunit.

219594:LOC116485598
gene id: 219594:LOC116485598
uniprot id: A0A6J3CEX8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:ENGASE
gene id: 219594:ENGASE
uniprot id: A0A6J3DYM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 85 family.
messages: cytosol

219594:PRRX2
gene id: 219594:PRRX2
uniprot id: A0A6J3DXR8
uniprot id: A0A6J3E2S3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paired homeobox family.
messages: Nucleus

219594:HMGB3
gene id: 219594:HMGB3
uniprot id: A0A6J3DRG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HMGB family.
messages: Chromosome

219594:MRPL17
gene id: 219594:MRPL17
uniprot id: A0A6J3EKQ0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL17 family.

219594:PDZK1IP1
gene id: 219594:PDZK1IP1
uniprot id: A0A6J3DE80
names: Subcellular Location Annotation
messages: Membrane

219594:TBCCD1
gene id: 219594:TBCCD1
uniprot id: A0A6J3DF18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TBCC family.
messages: centrosome
messages: spindle pole

219594:FGFBP3
gene id: 219594:FGFBP3
uniprot id: A0A6J3DA05
names: Similarity
messages: Belongs to the fibroblast growth factor-binding protein family.

219594:CKMT1A
gene id: 219594:CKMT1A
uniprot id: A0A6J3DG80
names: Similarity
messages: Belongs to the ATP:guanido phosphotransferase family.

219594:OTX2
gene id: 219594:OTX2
uniprot id: A0A6J3D3A4
uniprot id: A0A6J3D3K4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paired homeobox family. Bicoid subfamily.
messages: Nucleus

219594:LOC116498292
gene id: 219594:LOC116498292
uniprot id: A0A6J3E8J3
names: Subcellular Location Annotation
messages: Membrane

219594:LOC116489844
gene id: 219594:LOC116489844
uniprot id: A0A6J3D5H4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family.
messages: Secreted

219594:LOC116490372
gene id: 219594:LOC116490372
uniprot id: A0A6J3D7Z2
uniprot id: A0A6J3D802
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SCC3 family.
messages: Chromosome
messages: Component of cohesin complex, a complex required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate.
messages: Nucleus
messages: Part of the cohesin complex which is composed of a heterodimer between a SMC1 protein (SMC1A or SMC1B) and SMC3, which are attached via their hinge domain, and RAD21 which link them at their heads, and one STAG protein.
messages: centromere

219594:STARD9
gene id: 219594:STARD9
uniprot id: A0A6J3CZH8
uniprot id: A0A6J3CZR2
uniprot id: A0A6J3D216
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

219594:SLC25A13
gene id: 219594:SLC25A13
uniprot id: A0A6J3CGM8
uniprot id: A0A6J3CIK3
uniprot id: A0A6J3CK88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

219594:ITM2A
gene id: 219594:ITM2A
uniprot id: A0A6J3DRF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ITM2 family.
messages: Membrane

219594:LOC116499204
gene id: 219594:LOC116499204
uniprot id: A0A6J3ECY7
names: Similarity
messages: Belongs to the TGF-beta family.

219594:KIF26A
gene id: 219594:KIF26A
uniprot id: A0A6J3CYU8
uniprot id: A0A6J3D4V2
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

219594:LOC116487473
gene id: 219594:LOC116487473
uniprot id: A0A6J3CTW2
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

219594:CCDC90B
gene id: 219594:CCDC90B
uniprot id: A0A6J3EPD0
names: Similarity
messages: Belongs to the CCDC90 family.

219594:RNPS1
gene id: 219594:RNPS1
uniprot id: A0A6J3DQJ3
uniprot id: A0A6J3DUX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the splicing factor SR family.
messages: Nucleus speckle

219594:ZIC4
gene id: 219594:ZIC4
uniprot id: A0A6J3DDM8
uniprot id: A0A6J3DHL4
uniprot id: A0A6J3DJR8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GLI C2H2-type zinc-finger protein family.
messages: Nucleus

219594:MAGT1
gene id: 219594:MAGT1
uniprot id: A0A6J3DRH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OST3/OST6 family.
messages: Cell membrane
messages: Endoplasmic reticulum membrane
messages: Membrane

219594:CNR2
gene id: 219594:CNR2
uniprot id: A0A6J3EAH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:YME1L1
gene id: 219594:YME1L1
uniprot id: A0A6J3CEM2
names: Similarity
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the N-terminal section; belongs to the AAA ATPase family.

219594:ACOT8
gene id: 219594:ACOT8
uniprot id: A0A6J3DY06
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

219594:ITIH5
gene id: 219594:ITIH5
uniprot id: A0A6J3CU45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ITIH family.
messages: Secreted

219594:LOC116501324
gene id: 219594:LOC116501324
uniprot id: A0A6J3EG73
names: Subcellular Location Annotation
messages: Membrane

219594:TMEM38A
gene id: 219594:TMEM38A
uniprot id: A0A6J3E8X0
uniprot id: A0A6J3EE55
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM38 family.
messages: Membrane
messages: Monovalent cation channel required for maintenance of rapid intracellular calcium release. May act as a potassium counter-ion channel that functions in synchronization with calcium release from intracellular stores.

219594:PPP1R16B
gene id: 219594:PPP1R16B
uniprot id: A0A6J3DW27
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

219594:PYROXD1
gene id: 219594:PYROXD1
uniprot id: A0A6J3CRY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. PYROXD1 subfamily.
messages: sarcomere

219594:CIAO1
gene id: 219594:CIAO1
uniprot id: A0A6J3ED71
names: Function
names: Similarity
names: Subunit
messages: Belongs to the WD repeat CIA1 family.
messages: Component of the CIA complex.
messages: Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins.

219594:LOC116501384
gene id: 219594:LOC116501384
uniprot id: A0A6J3ELM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Homer family.
messages: Cytoplasm
messages: Postsynaptic density
messages: Synapse

219594:HNRNPD
gene id: 219594:HNRNPD
uniprot id: A0A6J3D0K7
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

219594:NFKB2
gene id: 219594:NFKB2
uniprot id: A0A6J3DCJ8
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

219594:CREBBP
gene id: 219594:CREBBP
uniprot id: A0A6J3DP32
uniprot id: A0A6J3DRD8
uniprot id: A0A6J3DTC8
uniprot id: A0A6J3DUC5
uniprot id: A0A6J3DUC9
uniprot id: A0A6J3DV67
uniprot id: A0A6J3DV74
names: Subcellular Location Annotation
messages: Cytoplasm

219594:ADRA1B
gene id: 219594:ADRA1B
uniprot id: A0A6J3DUA1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Cytoplasm
messages: Membrane
messages: This alpha-adrenergic receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. Its effect is mediated by G(q) and G(11) proteins. Nuclear ADRA1A-ADRA1B heterooligomers regulate phenylephrine (PE)-stimulated ERK signaling in cardiac myocytes.
messages: caveola

219594:BTF3L4
gene id: 219594:BTF3L4
uniprot id: A0A6J3DCR4
names: Similarity
messages: Belongs to the NAC-beta family.

219594:RBM15
gene id: 219594:RBM15
uniprot id: A0A6J3E5Y2
names: Similarity
messages: Belongs to the RRM Spen family.

219594:SAXO1
gene id: 219594:SAXO1
uniprot id: A0A6J3ED90
names: Similarity
messages: Belongs to the FAM154 family.

219594:IPO13
gene id: 219594:IPO13
uniprot id: A0A6J3DGJ1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the importin beta family.
messages: Cytoplasm
messages: Interacts with UBC9, RAN, RBM8A, eIF-1A and PAX6.
messages: Nucleus

219594:LOC116498287
gene id: 219594:LOC116498287
uniprot id: A0A6J3E5K3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family.
messages: Cell membrane
messages: Membrane

219594:PKNOX1
gene id: 219594:PKNOX1
uniprot id: A0A6J3DE28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/MEIS homeobox family.
messages: Nucleus

219594:LOC116490512
gene id: 219594:LOC116490512
uniprot id: A0A6J3D7T6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
messages: cytoskeleton

219594:NATD1
gene id: 219594:NATD1
uniprot id: A0A6J3DVW0
names: Similarity
messages: Belongs to the NATD1 family.

219594:CRYBG3
gene id: 219594:CRYBG3
uniprot id: A0A6J3CCA3
uniprot id: A0A6J3CCB5
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

219594:NHS
gene id: 219594:NHS
uniprot id: A0A6J3CI34
names: Similarity
messages: Belongs to the NHS family.

219594:SLC13A5
gene id: 219594:SLC13A5
uniprot id: A0A6J3DZS3
uniprot id: A0A6J3E3Z5
uniprot id: A0A6J3E5V7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. NADC subfamily.
messages: Membrane

219594:LOC116485802
gene id: 219594:LOC116485802
uniprot id: A0A6J3CFY9
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

219594:ABCC8
gene id: 219594:ABCC8
uniprot id: A0A6J3D1L1
names: Subunit
messages: Interacts with KCNJ11.

219594:LOC116492768
gene id: 219594:LOC116492768
uniprot id: A0A6J3DJD6
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a 'chicken-wire' meshwork together with laminins, proteoglycans and entactin/nidogen.
messages: basement membrane

219594:LOC116500145
gene id: 219594:LOC116500145
uniprot id: A0A6J3EFZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:GSX2
gene id: 219594:GSX2
uniprot id: A0A6J3CUV5
names: Subcellular Location Annotation
messages: Nucleus

219594:ADAMTS8
gene id: 219594:ADAMTS8
uniprot id: A0A6J3E3X1
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

219594:RALY
gene id: 219594:RALY
uniprot id: A0A6J3DRY6
names: Similarity
messages: Belongs to the RRM HNRPC family. RALY subfamily.

219594:LOC116496233
gene id: 219594:LOC116496233
uniprot id: A0A6J3DYR9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide-sugar transporter family. SLC35A subfamily.
messages: Membrane

219594:NDUFB3
gene id: 219594:NDUFB3
uniprot id: A0A6J3DAW3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFB3 subunit family.
messages: Mitochondrion inner membrane

219594:LOC116502376
gene id: 219594:LOC116502376
uniprot id: A0A6J3ELJ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone H3 family.
messages: Belongs to the histone H4 family.
messages: Chromosome
messages: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
messages: Nucleus

219594:SPOPL
gene id: 219594:SPOPL
uniprot id: A0A6J3D946
names: Similarity
messages: Belongs to the Tdpoz family.

219594:WDR55
gene id: 219594:WDR55
uniprot id: A0A6J3DTV7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat WDR55 family.
messages: Nucleolar protein that acts as a modulator of rRNA synthesis. Plays a central role during organogenesis.
messages: nucleolus

219594:SGCE
gene id: 219594:SGCE
uniprot id: A0A6J3CGT6
uniprot id: A0A6J3CHT6
uniprot id: A0A6J3CJP8
uniprot id: A0A6J3CLE3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sarcoglycan alpha/epsilon family.
messages: Component of the sarcoglycan complex, a subcomplex of the dystrophin-glycoprotein complex which forms a link between the F-actin cytoskeleton and the extracellular matrix.
messages: Golgi apparatus
messages: dendrite
messages: sarcolemma

219594:ALX4
gene id: 219594:ALX4
uniprot id: A0A6J3D4F6
names: Subcellular Location Annotation
messages: Nucleus

219594:SDR42E1
gene id: 219594:SDR42E1
uniprot id: A0A6J3DMF7
uniprot id: A0A6J3DR39
names: Similarity
messages: Belongs to the 3-beta-HSD family.

219594:LOC116485592
gene id: 219594:LOC116485592
uniprot id: A0A6J3CHS8
names: Subcellular Location Annotation
messages: Golgi apparatus membrane
messages: Membrane

219594:PDE7B
gene id: 219594:PDE7B
uniprot id: A0A6J3CR59
uniprot id: A0A6J3CRU7
uniprot id: A0A6J3CU60
uniprot id: A0A6J3CV97
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

219594:ADGRG2
gene id: 219594:ADGRG2
uniprot id: A0A6J3EJN4
uniprot id: A0A6J3EQ13
uniprot id: A0A6J3EQ19
uniprot id: A0A6J3ERH0
names: Subcellular Location Annotation
messages: Membrane

219594:LOC116500981
gene id: 219594:LOC116500981
uniprot id: A0A6J3EJV6
names: Subcellular Location Annotation
messages: Membrane

219594:RNF157
gene id: 219594:RNF157
uniprot id: A0A6J3E290
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: E3 ubiquitin ligase.

219594:SLC35E3
gene id: 219594:SLC35E3
uniprot id: A0A6J3EE63
names: Subcellular Location Annotation
messages: Membrane

219594:CNP
gene id: 219594:CNP
uniprot id: A0A6J3EAV9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 2H phosphoesterase superfamily. CNPase family.
messages: Exists as monomers and homodimers.
messages: Melanosome
messages: Membrane

219594:TUBE1
gene id: 219594:TUBE1
uniprot id: A0A6J3CPM5
uniprot id: A0A6J3CVQ6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: cytoskeleton

219594:DOP1A
gene id: 219594:DOP1A
uniprot id: A0A6J3CQX8
uniprot id: A0A6J3CTP4
uniprot id: A0A6J3CTP9
uniprot id: A0A6J3CVZ0
uniprot id: A0A6J3CX31
names: Similarity
messages: Belongs to the dopey family.

219594:SFT2D2
gene id: 219594:SFT2D2
uniprot id: A0A6J3EKK3
uniprot id: A0A6J3EPJ0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SFT2 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: May be involved in fusion of retrograde transport vesicles derived from an endocytic compartment with the Golgi complex.
messages: Membrane

219594:MEX3B
gene id: 219594:MEX3B
uniprot id: A0A6J3DPG5
names: Subcellular Location Annotation
messages: Cytoplasm

219594:PTH
gene id: 219594:PTH
uniprot id: A0A6J3D2B2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the parathyroid hormone family.
messages: PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion.
messages: Secreted

219594:ATPAF2
gene id: 219594:ATPAF2
uniprot id: A0A6J3DU73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP12 family.
messages: Mitochondrion

219594:ACER2
gene id: 219594:ACER2
uniprot id: A0A6J3EJ49
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alkaline ceramidase family.
messages: Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

219594:BASP1
gene id: 219594:BASP1
uniprot id: A0A6J3CMM7
names: Similarity
messages: Belongs to the BASP1 family.

219594:AMPD2
gene id: 219594:AMPD2
uniprot id: A0A6J3E865
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.

219594:LOC116494402
gene id: 219594:LOC116494402
uniprot id: A0A6J3DRD4
uniprot id: A0A6J3DSC2
names: Similarity
messages: Belongs to the CNKSR family.

219594:RPS20
gene id: 219594:RPS20
uniprot id: A0A6J3CLL4
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Component of the 40S small ribosomal subunit.

219594:LOC116486200
gene id: 219594:LOC116486200
uniprot id: A0A6J3CMT4
names: Function
messages: Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.

219594:LVRN
gene id: 219594:LVRN
uniprot id: A0A6J3EF06
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.

219594:LOC116500648
gene id: 219594:LOC116500648
uniprot id: A0A6J3EI31
names: Similarity
messages: Belongs to the osteocalcin/matrix Gla protein family.

219594:RPL32
gene id: 219594:RPL32
uniprot id: A0A6J3DEM6
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL32 family.

219594:ACTRT2
gene id: 219594:ACTRT2
uniprot id: A0A6J3E6G2
names: Similarity
messages: Belongs to the actin family.

219594:LOC116486700
gene id: 219594:LOC116486700
uniprot id: A0A6J3CKM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel (TC 2.A.49) family.
messages: Membrane

219594:SLC1A1
gene id: 219594:SLC1A1
uniprot id: A0A6J3EJP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

219594:LGALS3
gene id: 219594:LGALS3
uniprot id: A0A6J3CZU6
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus
messages: Secreted

219594:SBF2
gene id: 219594:SBF2
uniprot id: A0A6J3CYF7
uniprot id: A0A6J3D0Y3
uniprot id: A0A6J3D3F3
uniprot id: A0A6J3D4G4
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.

219594:GNG4
gene id: 219594:GNG4
uniprot id: A0A6J3CQ38
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G protein gamma family.
messages: Cell membrane
messages: G proteins are composed of 3 units; alpha, beta and gamma.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

219594:LOC116498782
gene id: 219594:LOC116498782
uniprot id: A0A6J3ECN9
names: Similarity
messages: Belongs to the DNA photolyase class-1 family.

219594:LOC116496921
gene id: 219594:LOC116496921
uniprot id: A0A6J3E2Z0
names: Similarity
messages: Belongs to the glutamine synthetase family.

219594:FGF13
gene id: 219594:FGF13
uniprot id: A0A6J3DLR3
uniprot id: A0A6J3DR05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heparin-binding growth factors family.
messages: Cytoplasm
messages: dendrite
messages: filopodium
messages: growth cone
messages: sarcolemma

219594:BTK
gene id: 219594:BTK
uniprot id: A0A6J3DL03
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

219594:VPS26C
gene id: 219594:VPS26C
uniprot id: A0A6J3EKY6
names: Similarity
messages: Belongs to the VPS26 family.

219594:LOC116490844
gene id: 219594:LOC116490844
uniprot id: A0A6J3D7L8
uniprot id: A0A6J3DAD1
names: Subcellular Location Annotation
names: Subunit
messages: Apical cell membrane
messages: Cell membrane
messages: Homodimer.
messages: Membrane

219594:GCHFR
gene id: 219594:GCHFR
uniprot id: A0A6J3CX29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GFRP family.
messages: Membrane
messages: Nucleus membrane
messages: cytosol

219594:CREB3L4
gene id: 219594:CREB3L4
uniprot id: A0A6J3EE31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. ATF subfamily.
messages: Endoplasmic reticulum membrane
messages: Membrane

219594:EIF3F
gene id: 219594:EIF3F
uniprot id: A0A6J3D9Y3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit F family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
messages: Cytoplasm

219594:CHPF
gene id: 219594:CHPF
uniprot id: A0A6J3D546
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chondroitin N-acetylgalactosaminyltransferase family.
messages: Golgi stack membrane
messages: Membrane

219594:SMARCD2
gene id: 219594:SMARCD2
uniprot id: A0A6J3E4Q9
names: Similarity
messages: Belongs to the SMARCD family.

219594:SELE
gene id: 219594:SELE
uniprot id: A0A6J3DFJ5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the selectin/LECAM family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

219594:LOC116496709
gene id: 219594:LOC116496709
uniprot id: A0A6J3E1S7
names: Subcellular Location Annotation
names: Subunit
messages: Cell membrane
messages: Interacts with NCDN.
messages: Membrane

219594:POU3F1
gene id: 219594:POU3F1
uniprot id: A0A6J3E885
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POU transcription factor family. Class-3 subfamily.
messages: Nucleus

219594:ADGB
gene id: 219594:ADGB
uniprot id: A0A6J3CNY0
names: Caution
names: Similarity
messages: Belongs to the globin family.
messages: Belongs to the peptidase C2 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:HIPK4
gene id: 219594:HIPK4
uniprot id: A0A6J3CSN3
names: Similarity
messages: Belongs to the protein kinase superfamily.

219594:PIGO
gene id: 219594:PIGO
uniprot id: A0A6J3EFJ6
uniprot id: A0A6J3EKU8
uniprot id: A0A6J3EM91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGG/PIGN/PIGO family. PIGO subfamily.
messages: Endoplasmic reticulum membrane
messages: Membrane

219594:TOP3A
gene id: 219594:TOP3A
uniprot id: A0A6J3DVG4
names: Function
names: Similarity
messages: Belongs to the type IA topoisomerase family.
messages: Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand.

219594:HOXD4
gene id: 219594:HOXD4
uniprot id: A0A6J3D4U1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus

219594:INTS9
gene id: 219594:INTS9
uniprot id: A0A6J3CN79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. INTS9 subfamily.
messages: Nucleus

219594:LOC116486297
gene id: 219594:LOC116486297
uniprot id: A0A6J3CIM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM170 family.
messages: Membrane

219594:CDH22
gene id: 219594:CDH22
uniprot id: A0A6J3DX48
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane
messages: Membrane

219594:AFF2
gene id: 219594:AFF2
uniprot id: A0A6J3DN04
uniprot id: A0A6J3DPT5
uniprot id: A0A6J3DR00
uniprot id: A0A6J3DRT6
names: Similarity
messages: Belongs to the AF4 family.

219594:LOC116486304
gene id: 219594:LOC116486304
uniprot id: A0A6J3CLM7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase subunit 6c family.
messages: Component of the cytochrome c oxidase (complex IV, CIV), a multisubunit enzyme composed of 14 subunits. The complex is composed of a catalytic core of 3 subunits MT-CO1, MT-CO2 and MT-CO3, encoded in the mitochondrial DNA, and 11 supernumerary subunits COX4I, COX5A, COX5B, COX6A, COX6B, COX6C, COX7A, COX7B, COX7C, COX8 and NDUFA4, which are encoded in the nuclear genome. The complex exists as a monomer or a dimer and forms supercomplexes (SCs) in the inner mitochondrial membrane with NADH-ubiquinone oxidoreductase (complex I, CI) and ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII), resulting in different assemblies (supercomplex SCI(1)III(2)IV(1) and megacomplex MCI(2)III(2)IV(2)).
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
messages: Membrane
messages: Mitochondrion inner membrane

219594:BUD13
gene id: 219594:BUD13
uniprot id: A0A6J3E465
uniprot id: A0A6J3E735
uniprot id: A0A6J3E7R2
uniprot id: A0A6J3E960
names: Similarity
messages: Belongs to the CWC26 family.

219594:TNFSF8
gene id: 219594:TNFSF8
uniprot id: A0A6J3DYW4
names: Similarity
messages: Belongs to the tumor necrosis factor family.

219594:LOC116499453
gene id: 219594:LOC116499453
uniprot id: A0A6J3EA63
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-1 family.
messages: Secreted

219594:ORMDL3
gene id: 219594:ORMDL3
uniprot id: A0A6J3E8W2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ORM family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Negative regulator of sphingolipid synthesis.

219594:TMEM63A
gene id: 219594:TMEM63A
uniprot id: A0A6J3CUC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSC1 (TC 1.A.17) family.
messages: Membrane

219594:PRKG2
gene id: 219594:PRKG2
uniprot id: A0A6J3CY27
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. cGMP subfamily.

219594:LOC116488262
gene id: 219594:LOC116488262
uniprot id: A0A6J3CRB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TGF-beta family.
messages: Secreted

219594:SENP6
gene id: 219594:SENP6
uniprot id: A0A6J3CMY9
uniprot id: A0A6J3CR82
uniprot id: A0A6J3CS92
names: Similarity
messages: Belongs to the peptidase C48 family.

219594:BPI
gene id: 219594:BPI
uniprot id: A0A6J3DYD8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family.
messages: Cytoplasmic granule membrane
messages: Membrane
messages: Monomer. Homodimer; disulfide-linked.
messages: Secreted
messages: The N- and C-terminal barrels adopt an identical fold despite having only 13% of conserved residues.
messages: The N-terminal region may be exposed to the interior of the granule, whereas the C-terminal portion may be embedded in the membrane. During phagocytosis and degranulation, proteases may be released and activated and cleave BPI at the junction of the N- and C-terminal portions of the molecule, providing controlled release of the N-terminal antibacterial fragment when bacteria are ingested.
messages: The cytotoxic action of BPI is limited to many species of Gram-negative bacteria; this specificity may be explained by a strong affinity of the very basic N-terminal half for the negatively charged lipopolysaccharides that are unique to the Gram-negative bacterial outer envelope.

219594:HHIP
gene id: 219594:HHIP
uniprot id: A0A6J3CU03
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:CHRND
gene id: 219594:CHRND
uniprot id: A0A6J3DI02
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

219594:CNOT6L
gene id: 219594:CNOT6L
uniprot id: A0A6J3CX57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCR4/nocturin family.
messages: Cytoplasm
messages: Nucleus

219594:IMP3
gene id: 219594:IMP3
uniprot id: A0A6J3CQY6
names: Similarity
messages: Belongs to the universal ribosomal protein uS4 family.

219594:CCM2
gene id: 219594:CCM2
uniprot id: A0A6J3CF15
names: Similarity
messages: Belongs to the CCM2 family.

219594:MERTK
gene id: 219594:MERTK
uniprot id: A0A6J3CRV5
uniprot id: A0A6J3CU71
uniprot id: A0A6J3CVA9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.
messages: Membrane

219594:PLOD1
gene id: 219594:PLOD1
uniprot id: A0A6J3E773
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane

219594:PRPF18
gene id: 219594:PRPF18
uniprot id: A0A6J3EN07
uniprot id: A0A6J3EPE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRP18 family.
messages: Nucleus speckle

219594:LOC116493649
gene id: 219594:LOC116493649
uniprot id: A0A6J3DKH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDC42SE/SPEC family.
messages: Cell membrane
messages: Membrane
messages: cytoskeleton

219594:IFT43
gene id: 219594:IFT43
uniprot id: A0A6J3D1K4
uniprot id: A0A6J3D1M8
uniprot id: A0A6J3D436
uniprot id: A0A6J3D528
names: Similarity
messages: Belongs to the IFT43 family.

219594:ANGPTL4
gene id: 219594:ANGPTL4
uniprot id: A0A6J3EC21
names: Subcellular Location Annotation
messages: Secreted

219594:GAS6
gene id: 219594:GAS6
uniprot id: A0A6J3E225
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:LIMK1
gene id: 219594:LIMK1
uniprot id: A0A6J3E4H9
names: Similarity
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family.

219594:HEPH
gene id: 219594:HEPH
uniprot id: A0A6J3DQZ7
uniprot id: A0A6J3DRY4
uniprot id: A0A6J3DSZ1
names: Similarity
messages: Belongs to the multicopper oxidase family.

219594:TLX3
gene id: 219594:TLX3
uniprot id: A0A6J3DSY6
names: Subcellular Location Annotation
messages: Nucleus

219594:ST8SIA2
gene id: 219594:ST8SIA2
uniprot id: A0A6J3DNQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

219594:LOC116493572
gene id: 219594:LOC116493572
uniprot id: A0A6J3DLM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family.
messages: Endoplasmic reticulum

219594:MGAT5
gene id: 219594:MGAT5
uniprot id: A0A6J3D6E1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 18 family.
messages: Golgi apparatus membrane
messages: Membrane
messages: Secreted

219594:MYC
gene id: 219594:MYC
uniprot id: A0A6J3CKY5
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Efficient DNA binding requires dimerization with another bHLH protein.
messages: Nucleus
messages: Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes.

219594:LOC116497967
gene id: 219594:LOC116497967
uniprot id: A0A6J3E996
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Membrane

219594:LOC116495333
gene id: 219594:LOC116495333
uniprot id: A0A6J3DWE8
names: Similarity
messages: Belongs to the cytochrome P450 family.

219594:FAIM2
gene id: 219594:FAIM2
uniprot id: A0A6J3EFI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

219594:HDAC8
gene id: 219594:HDAC8
uniprot id: A0A6J3DT74
names: Similarity
messages: Belongs to the histone deacetylase family. HD type 1 subfamily.

219594:HTR2C
gene id: 219594:HTR2C
uniprot id: A0A6J3DRW6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Interacts with MPDZ. Interacts with ARRB2.
messages: Membrane

219594:NDRG3
gene id: 219594:NDRG3
uniprot id: A0A6J3DRQ8
uniprot id: A0A6J3DXW7
names: Similarity
messages: Belongs to the NDRG family.

219594:RNF182
gene id: 219594:RNF182
uniprot id: A0A6J3CI30
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Interacts with ATP6V0C.
messages: Membrane

219594:LOC116494982
gene id: 219594:LOC116494982
uniprot id: A0A6J3DSV9
names: Subcellular Location Annotation
messages: Secreted

219594:LOC116487948
gene id: 219594:LOC116487948
uniprot id: A0A6J3ENP0
names: Similarity
names: Subunit
messages: Belongs to the histone H3 family.
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

219594:PLA2G1B
gene id: 219594:PLA2G1B
uniprot id: A0A6J3DZA6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase A2 family.
messages: Binds 1 Ca(2+) ion per subunit.
messages: Secreted

219594:TM2D2
gene id: 219594:TM2D2
uniprot id: A0A6J3EF45
names: Subcellular Location Annotation
messages: Membrane

219594:PTGR1
gene id: 219594:PTGR1
uniprot id: A0A6J3EEM6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NADP-dependent oxidoreductase L4BD family.
messages: Cytoplasm
messages: Monomer or homodimer.

219594:TPM2
gene id: 219594:TPM2
uniprot id: A0A6J3EED6
uniprot id: A0A6J3EEE1
uniprot id: A0A6J3EFU1
uniprot id: A0A6J3EFU6
uniprot id: A0A6J3EFV1
uniprot id: A0A6J3EGR7
uniprot id: A0A6J3EI99
uniprot id: A0A6J3EJF5
uniprot id: A0A6J3EJJ8
uniprot id: A0A6J3EL51
uniprot id: A0A6J3EL56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tropomyosin family.
messages: cytoskeleton

219594:APOB
gene id: 219594:APOB
uniprot id: A0A6J3CVV9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:PEX10
gene id: 219594:PEX10
uniprot id: A0A6J3E208
uniprot id: A0A6J3E6Q4
names: Function
names: Similarity
messages: Belongs to the pex2/pex10/pex12 family.
messages: Somewhat implicated in the biogenesis of peroxisomes.

219594:LOC116498568
gene id: 219594:LOC116498568
uniprot id: A0A6J3EA76
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with GIRK2, GIRK3 or GIRK4 to form a G-protein activated heteromultimer pore-forming unit. The resulting inward current is much larger.
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family. KCNJ3 subfamily.
messages: Membrane
messages: This potassium channel is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. This receptor plays a crucial role in regulating the heartbeat.

219594:ATP9A
gene id: 219594:ATP9A
uniprot id: A0A6J3DX99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

219594:EXOSC2
gene id: 219594:EXOSC2
uniprot id: A0A6J3E2V2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRP4 family.
messages: Cytoplasm

219594:DOK6
gene id: 219594:DOK6
uniprot id: A0A6J3CG37
names: Similarity
messages: Belongs to the DOK family. Type B subfamily.

219594:PARP9
gene id: 219594:PARP9
uniprot id: A0A6J3D4Z4
names: Similarity
messages: Belongs to the ARTD/PARP family.

219594:SLC35C1
gene id: 219594:SLC35C1
uniprot id: A0A6J3D1E2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TPT transporter family. SLC35C subfamily.
messages: Membrane

219594:MTO1
gene id: 219594:MTO1
uniprot id: A0A6J3CXE1
names: Function
names: Similarity
messages: Belongs to the MnmG family.
messages: Involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U34) of the wobble uridine base in mitochondrial tRNAs.

219594:VPS36
gene id: 219594:VPS36
uniprot id: A0A6J3DN74
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the VPS36 family.
messages: Component of the ESCRT-II complex (endosomal sorting complex required for transport II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs.
messages: Component of the endosomal sorting complex required for transport II (ESCRT-II).
messages: Cytoplasm
messages: Endosome

219594:LOC116486358
gene id: 219594:LOC116486358
uniprot id: A0A6J3CLZ9
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

219594:UBE3D
gene id: 219594:UBE3D
uniprot id: A0A6J3CMU7
names: Function
messages: E3 ubiquitin-protein ligase which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, and transfers it to substrates, generally promoting their degradation by the proteasome.

219594:C18H17orf80
gene id: 219594:C18H17orf80
uniprot id: A0A6J3E1Q5
names: Function
names: Similarity
messages: Belongs to the ATPase F chain family.
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. Minor subunit located with subunit a in the membrane.

219594:SLC41A3
gene id: 219594:SLC41A3
uniprot id: A0A6J3DJL5
uniprot id: A0A6J3DL79
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

219594:LOC116494703
gene id: 219594:LOC116494703
uniprot id: A0A6J3DMC6
names: Similarity
messages: Belongs to the DCK/DGK family.

219594:TWSG1
gene id: 219594:TWSG1
uniprot id: A0A6J3CM70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the twisted gastrulation protein family.
messages: Secreted

219594:DBR1
gene id: 219594:DBR1
uniprot id: A0A6J3DGY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lariat debranching enzyme family.
messages: Nucleus

219594:SFN
gene id: 219594:SFN
uniprot id: A0A6J3E545
names: Similarity
messages: Belongs to the 14-3-3 family.

219594:CLSTN1
gene id: 219594:CLSTN1
uniprot id: A0A6J3E1Q9
uniprot id: A0A6J3E318
uniprot id: A0A6J3E5Z0
uniprot id: A0A6J3E7Y7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Golgi apparatus membrane
messages: Membrane

219594:PRORP
gene id: 219594:PRORP
uniprot id: A0A6J3D486
names: Similarity
messages: Belongs to the PPR family. P subfamily.

219594:INSRR
gene id: 219594:INSRR
uniprot id: A0A6J3EDR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. Insulin receptor subfamily.
messages: Membrane

219594:HS6ST3
gene id: 219594:HS6ST3
uniprot id: A0A6J3EQJ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 6-O-sulfation enzyme which catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to position 6 of the N-sulfoglucosamine residue (GlcNS) of heparan sulfate.
messages: Belongs to the sulfotransferase 6 family.
messages: Membrane

219594:NAPRT
gene id: 219594:NAPRT
uniprot id: A0A6J3CFW9
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

219594:TULP1
gene id: 219594:TULP1
uniprot id: A0A6J3EB27
names: Similarity
messages: Belongs to the TUB family.

219594:LOC116501336
gene id: 219594:LOC116501336
uniprot id: A0A6J3ELJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:EREG
gene id: 219594:EREG
uniprot id: A0A6J3D1E9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:BOK
gene id: 219594:BOK
uniprot id: A0A6J3DD55
uniprot id: A0A6J3DIP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Bcl-2 family.
messages: Membrane

219594:RAB39B
gene id: 219594:RAB39B
uniprot id: A0A6J3DPV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Cell membrane
messages: Membrane

219594:LOC116486883
gene id: 219594:LOC116486883
uniprot id: A0A6J3CJZ9
names: Similarity
names: Subunit
messages: Belongs to the avian keratin family.
messages: The avian keratins (F-ker, S-ker, C-ker and B-ker) are a complex mixture of very similar polypeptides.

219594:ATPSCKMT
gene id: 219594:ATPSCKMT
uniprot id: A0A6J3CJK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ANT/ATPSC lysine N-methyltransferase family.
messages: Mitochondrion membrane

219594:RARA
gene id: 219594:RARA
uniprot id: A0A6J3E9P7
uniprot id: A0A6J3EBR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

219594:LOC116500190
gene id: 219594:LOC116500190
uniprot id: A0A6J3EGE5
uniprot id: A0A6J3EI03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the actinoporin family. Sea anemone subfamily.
messages: Cell membrane
messages: Membrane
messages: Nematocyst
messages: Target cell membrane

219594:ADAMTS14
gene id: 219594:ADAMTS14
uniprot id: A0A6J3DAQ5
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

219594:CASS4
gene id: 219594:CASS4
uniprot id: A0A6J3DXN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAS family.
messages: focal adhesion

219594:DLL1
gene id: 219594:DLL1
uniprot id: A0A6J3CRU8
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Putative Notch ligand involved in the mediation of Notch signaling.

219594:PITHD1
gene id: 219594:PITHD1
uniprot id: A0A6J3E4W9
names: Similarity
messages: Belongs to the PITHD1 family.

219594:PDHB
gene id: 219594:PDHB
uniprot id: A0A6J3DI45
names: Function
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and thereby links the glycolytic pathway to the tricarboxylic cycle.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.

219594:KCNK17
gene id: 219594:KCNK17
uniprot id: A0A6J3CTZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

219594:FKTN
gene id: 219594:FKTN
uniprot id: A0A6J3EK54
names: Similarity
messages: Belongs to the LicD transferase family.

219594:MET
gene id: 219594:MET
uniprot id: A0A6J3CLI9
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

219594:RBX1
gene id: 219594:RBX1
uniprot id: A0A6J3EHR3
names: Similarity
messages: Belongs to the RING-box family.

219594:POMK
gene id: 219594:POMK
uniprot id: A0A6J3CY93
names: Function
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Protein O-mannose kinase that specifically mediates phosphorylation at the 6-position of an O-mannose of the trisaccharide (N-acetylgalactosamine (GalNAc)-beta-1,3-N-acetylglucosamine (GlcNAc)-beta-1,4-mannose) to generate phosphorylated O-mannosyl trisaccharide (N-acetylgalactosamine-beta-1,3-N-acetylglucosamine-beta-1,4-(phosphate-6-)mannose). Phosphorylated O-mannosyl trisaccharide is a carbohydrate structure present in alpha-dystroglycan (DAG1), which is required for binding laminin G-like domain-containing extracellular proteins with high affinity. Only shows kinase activity when the GalNAc-beta-3-GlcNAc-beta-terminus is linked to the 4-position of O-mannose, suggesting that this disaccharide serves as the substrate recognition motif.

219594:DCC
gene id: 219594:DCC
uniprot id: A0A6J3EJE3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. DCC family.
messages: Membrane

219594:CFDP1
gene id: 219594:CFDP1
uniprot id: A0A6J3DQD0
names: Function
names: Subcellular Location Annotation
messages: May play a role during embryogenesis.
messages: kinetochore

219594:LOC116501313
gene id: 219594:LOC116501313
uniprot id: A0A6J3ELH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:NR2C1
gene id: 219594:NR2C1
uniprot id: A0A6J3CTE7
uniprot id: A0A6J3CTF7
uniprot id: A0A6J3CX97
uniprot id: A0A6J3CXC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

219594:RPL15
gene id: 219594:RPL15
uniprot id: A0A6J3CKK2
names: Function
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL15 family.
messages: Component of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.

219594:LOC116499591
gene id: 219594:LOC116499591
uniprot id: A0A6J3EE97
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the selenium-binding protein family.
messages: Catalyzes the oxidation of methanethiol, an organosulfur compound known to be produced in substantial amounts by gut bacteria. Selenium-binding protein which may be involved in the sensing of reactive xenobiotics in the cytoplasm. May be involved in intra-Golgi protein transport.
messages: Membrane
messages: Nucleus
messages: cytosol

219594:TSPAN3
gene id: 219594:TSPAN3
uniprot id: A0A6J3DJP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

219594:RGS3
gene id: 219594:RGS3
uniprot id: A0A6J3DYI4
names: Subcellular Location Annotation
messages: Cytoplasm

219594:ELL
gene id: 219594:ELL
uniprot id: A0A6J3E8Z9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELL/occludin family.
messages: Nucleus

219594:ALG13
gene id: 219594:ALG13
uniprot id: A0A6J3DR55
names: Similarity
messages: Belongs to the glycosyltransferase 28 family.

219594:LAMTOR3
gene id: 219594:LAMTOR3
uniprot id: A0A6J3CW92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LAMTOR3 family.
messages: Endosome membrane
messages: Late endosome membrane

219594:CMTM4
gene id: 219594:CMTM4
uniprot id: A0A6J3DN06
names: Subcellular Location Annotation
messages: Membrane

219594:QPCT
gene id: 219594:QPCT
uniprot id: A0A6J3CR75
uniprot id: A0A6J3CXD6
names: Similarity
messages: Belongs to the glutaminyl-peptide cyclotransferase family.

219594:CRY1
gene id: 219594:CRY1
uniprot id: A0A6J3E2M6
names: Similarity
messages: Belongs to the DNA photolyase class-1 family.

219594:F13A1
gene id: 219594:F13A1
uniprot id: A0A6J3CI70
names: Cofactor
names: Similarity
messages: Belongs to the transglutaminase superfamily. Transglutaminase family.
messages: Binds 1 Ca(2+) ion per subunit.

219594:ADCY7
gene id: 219594:ADCY7
uniprot id: A0A6J3DK37
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Binds 2 magnesium ions per subunit. Is also active with manganese (in vitro).
messages: Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.
messages: Membrane

219594:LOC116500500
gene id: 219594:LOC116500500
uniprot id: A0A6J3ECK6
names: Similarity
messages: Belongs to the avidin/streptavidin family.

219594:LOC116498730
gene id: 219594:LOC116498730
uniprot id: A0A6J3EA79
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:PRDX1
gene id: 219594:PRDX1
uniprot id: A0A6J3DAY8
names: Function
names: Similarity
messages: Belongs to the peroxiredoxin family.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively.

219594:LOC116500235
gene id: 219594:LOC116500235
uniprot id: A0A6J3EG81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. BTN/MOG family.
messages: Membrane

219594:LOC116490345
gene id: 219594:LOC116490345
uniprot id: A0A6J3D4E6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COA8 family.
messages: Mitochondrion inner membrane

219594:LOC116489464
gene id: 219594:LOC116489464
uniprot id: A0A6J3CXH4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:LANCL3
gene id: 219594:LANCL3
uniprot id: A0A6J3DKH3
names: Similarity
messages: Belongs to the LanC-like protein family.

219594:CACNB4
gene id: 219594:CACNB4
uniprot id: A0A6J3D2S0
uniprot id: A0A6J3D5K8
uniprot id: A0A6J3D7U1
uniprot id: A0A6J3D8M5
names: Similarity
messages: Belongs to the calcium channel beta subunit family.

219594:SRF
gene id: 219594:SRF
uniprot id: A0A6J3CR38
names: Subcellular Location Annotation
messages: Nucleus

219594:DENND5B
gene id: 219594:DENND5B
uniprot id: A0A6J3DKF1
names: Caution
names: Similarity
messages: Belongs to the RAB6IP1 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:ARVCF
gene id: 219594:ARVCF
uniprot id: A0A6J3DV19
uniprot id: A0A6J3DWV6
uniprot id: A0A6J3DWW1
uniprot id: A0A6J3DWW5
uniprot id: A0A6J3DZ64
uniprot id: A0A6J3DZ70
uniprot id: A0A6J3DZ76
uniprot id: A0A6J3DZX2
uniprot id: A0A6J3E103
uniprot id: A0A6J3E109
names: Similarity
messages: Belongs to the beta-catenin family.

219594:KIF2A
gene id: 219594:KIF2A
uniprot id: A0A6J3ECD2
uniprot id: A0A6J3EDQ7
uniprot id: A0A6J3EH68
uniprot id: A0A6J3EHF6
uniprot id: A0A6J3EJ28
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

219594:RMI1
gene id: 219594:RMI1
uniprot id: A0A6J3EH48
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RMI1 family.
messages: Essential component of the RMI complex, a complex that plays an important role in the processing of homologous recombination intermediates to limit DNA crossover formation in cells. Promotes TOP3A binding to double Holliday junctions (DHJ) and hence stimulates TOP3A-mediated dissolution. Required for BLM phosphorylation during mitosis. Within the BLM complex, required for BLM and TOP3A stability.
messages: Nucleus

219594:LOC116489567
gene id: 219594:LOC116489567
uniprot id: A0A6J3D3V1
names: Domain
names: Subcellular Location Annotation
messages: The N-terminal C2 domain associates with lipid membranes upon calcium binding.
messages: cytosol

219594:CACNB2
gene id: 219594:CACNB2
uniprot id: A0A6J3CF14
uniprot id: A0A6J3CF19
uniprot id: A0A6J3CGP2
uniprot id: A0A6J3CHN5
uniprot id: A0A6J3CHP0
uniprot id: A0A6J3CJJ7
uniprot id: A0A6J3CJK1
uniprot id: A0A6J3CLA1
uniprot id: A0A6J3CLA6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calcium channel beta subunit family.
messages: The beta subunit of voltage-dependent calcium channels contributes to the function of the calcium channel by increasing peak calcium current, shifting the voltage dependencies of activation and inactivation, modulating G protein inhibition and controlling the alpha-1 subunit membrane targeting.
messages: sarcolemma

219594:LOC116492577
gene id: 219594:LOC116492577
uniprot id: A0A6J3DCQ2
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

219594:DTNBP1
gene id: 219594:DTNBP1
uniprot id: A0A6J3CLF2
names: Similarity
messages: Belongs to the dysbindin family.

219594:FGFBP1
gene id: 219594:FGFBP1
uniprot id: A0A6J3CS36
names: Similarity
messages: Belongs to the fibroblast growth factor-binding protein family.

219594:DONSON
gene id: 219594:DONSON
uniprot id: A0A6J3DQQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DONSON family.
messages: Nucleus

219594:PHKB
gene id: 219594:PHKB
uniprot id: A0A6J3DII4
uniprot id: A0A6J3DII9
uniprot id: A0A6J3DMN1
uniprot id: A0A6J3DPN1
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Although the final Cys may be farnesylated, the terminal tripeptide is probably not removed, and the C-terminus is not methylated.
messages: Belongs to the phosphorylase b kinase regulatory chain family.
messages: Cell membrane
messages: Membrane
messages: Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I.

219594:ARHGEF3
gene id: 219594:ARHGEF3
uniprot id: A0A6J3DEY0
uniprot id: A0A6J3DHM8
uniprot id: A0A6J3DKI4
uniprot id: A0A6J3DL28
names: Function
names: Subcellular Location Annotation
messages: Acts as guanine nucleotide exchange factor (GEF) for RhoA and RhoB GTPases.
messages: Cytoplasm

219594:CYYR1
gene id: 219594:CYYR1
uniprot id: A0A6J3DQE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CYYR1 family.
messages: Membrane

219594:ZDHHC12
gene id: 219594:ZDHHC12
uniprot id: A0A6J3E3P4
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

219594:PLA2R1
gene id: 219594:PLA2R1
uniprot id: A0A6J3D5B2
uniprot id: A0A6J3D8N9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:ACTR5
gene id: 219594:ACTR5
uniprot id: A0A6J3DU31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the actin family. ARP5 subfamily.
messages: Nucleus

219594:TFAP2E
gene id: 219594:TFAP2E
uniprot id: A0A6J3E829
names: Similarity
messages: Belongs to the AP-2 family.

219594:MAML2
gene id: 219594:MAML2
uniprot id: A0A6J3CYW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mastermind family.
messages: Nucleus speckle

219594:SNCA
gene id: 219594:SNCA
uniprot id: A0A6J3D0Y9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synuclein family.
messages: Membrane
messages: Nucleus
messages: Secreted
messages: Synapse

219594:PRKAG1
gene id: 219594:PRKAG1
uniprot id: A0A6J3EAE2
uniprot id: A0A6J3EF52
names: Similarity
names: Subunit
messages: AMPK is a heterotrimer of an alpha catalytic subunit (PRKAA1 or PRKAA2), a beta (PRKAB1 or PRKAB2) and a gamma non-catalytic subunits (PRKAG1, PRKAG2 or PRKAG3). Interacts with FNIP1 and FNIP2.
messages: Belongs to the 5'-AMP-activated protein kinase gamma subunit family.

219594:MICAL2
gene id: 219594:MICAL2
uniprot id: A0A6J3CXK7
uniprot id: A0A6J3CZZ1
uniprot id: A0A6J3D2G4
uniprot id: A0A6J3D3K3
uniprot id: A0A6J3D3K8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mical family.
messages: Cytoplasm

219594:LOC116501156
gene id: 219594:LOC116501156
uniprot id: A0A6J3EKM0
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MoaE family. MOCS2B subfamily.
messages: Catalytic subunit of the molybdopterin synthase complex, a complex that catalyzes the conversion of precursor Z into molybdopterin. Acts by mediating the incorporation of 2 sulfur atoms from thiocarboxylated MOCS2A into precursor Z to generate a dithiolene group.
messages: Heterotetramer; composed of 2 small (MOCS2A) and 2 large (MOCS2B) subunits.
messages: This protein is produced by a bicistronic gene which also produces the large subunit (MOCS2A).
messages: cytosol

219594:CSNK2A1
gene id: 219594:CSNK2A1
uniprot id: A0A6J3DTT9
names: Similarity
messages: Belongs to the protein kinase superfamily.

219594:STX18
gene id: 219594:STX18
uniprot id: A0A6J3D0E1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the syntaxin family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Syntaxin that may be involved in targeting and fusion of Golgi-derived retrograde transport vesicles with the ER.

219594:ADK
gene id: 219594:ADK
uniprot id: A0A6J3D5X5
uniprot id: A0A6J3DBT0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP dependent phosphorylation of adenosine and other related nucleoside analogs to monophosphate derivatives.
messages: Belongs to the carbohydrate kinase PfkB family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Monomer.
messages: Nucleus

219594:ACVR2A
gene id: 219594:ACVR2A
uniprot id: A0A6J3D6Y4
uniprot id: A0A6J3D9N4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Membrane

219594:PAPSS2
gene id: 219594:PAPSS2
uniprot id: A0A6J3D646
uniprot id: A0A6J3D9D2
names: Similarity
messages: In the C-terminal section; belongs to the sulfate adenylyltransferase family.
messages: In the N-terminal section; belongs to the APS kinase family.

219594:ANAPC1
gene id: 219594:ANAPC1
uniprot id: A0A6J3CPQ9
uniprot id: A0A6J3CS03
names: Similarity
messages: Belongs to the APC1 family.

219594:PFKFB4
gene id: 219594:PFKFB4
uniprot id: A0A6J3DH30
uniprot id: A0A6J3DIC0
uniprot id: A0A6J3DJX8
uniprot id: A0A6J3DKG6
names: Similarity
names: Subunit
messages: Homodimer.
messages: In the C-terminal section; belongs to the phosphoglycerate mutase family.

219594:LOC116489963
gene id: 219594:LOC116489963
uniprot id: A0A6J3D512
names: Similarity
messages: Belongs to the PRPH2/ROM1 family.

219594:SLC25A21
gene id: 219594:SLC25A21
uniprot id: A0A6J3CZ98
uniprot id: A0A6J3D1I5
uniprot id: A0A6J3D2M7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

219594:LOC116502198
gene id: 219594:LOC116502198
uniprot id: A0A6J3EKQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:DIP2B
gene id: 219594:DIP2B
uniprot id: A0A6J3EAI3
uniprot id: A0A6J3EBW2
uniprot id: A0A6J3EF90
names: Similarity
messages: Belongs to the DIP2 family.

219594:SLC12A8
gene id: 219594:SLC12A8
uniprot id: A0A6J3D9F9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC12A transporter family.
messages: Membrane

219594:GFOD2
gene id: 219594:GFOD2
uniprot id: A0A6J3DNJ4
names: Similarity
messages: Belongs to the Gfo/Idh/MocA family.

219594:ST3GAL1
gene id: 219594:ST3GAL1
uniprot id: A0A6J3CIN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

219594:SORD
gene id: 219594:SORD
uniprot id: A0A6J3DNL1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the zinc-containing alcohol dehydrogenase family.
messages: Mitochondrion membrane
messages: flagellum

219594:RIOK2
gene id: 219594:RIOK2
uniprot id: A0A6J3EFF1
uniprot id: A0A6J3EKK8
names: Similarity
messages: Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.

219594:CLCN4
gene id: 219594:CLCN4
uniprot id: A0A6J3EQ64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel (TC 2.A.49) family.
messages: Membrane

219594:FAM160B1
gene id: 219594:FAM160B1
uniprot id: A0A6J3D8N2
uniprot id: A0A6J3D968
names: Similarity
messages: Belongs to the FHIP family.

219594:LOC116490589
gene id: 219594:LOC116490589
uniprot id: A0A6J3D8N5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:KIF25
gene id: 219594:KIF25
uniprot id: A0A6J3CPC7
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

219594:CDC26
gene id: 219594:CDC26
uniprot id: A0A6J3E3D0
names: Similarity
messages: Belongs to the CDC26 family.

219594:BBS10
gene id: 219594:BBS10
uniprot id: A0A6J3EPY6
names: Similarity
messages: Belongs to the TCP-1 chaperonin family.

219594:LOC116485445
gene id: 219594:LOC116485445
uniprot id: A0A6J3CE18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cathelicidin family.
messages: Secreted

219594:SLC2A12
gene id: 219594:SLC2A12
uniprot id: A0A6J3CTV9
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

219594:DHTKD1
gene id: 219594:DHTKD1
uniprot id: A0A6J3DZ98
names: Similarity
messages: Belongs to the alpha-ketoglutarate dehydrogenase family.

219594:LOC116488954
gene id: 219594:LOC116488954
uniprot id: A0A6J3CX48
names: Similarity
messages: Belongs to the DOCK family.

219594:LOC116486624
gene id: 219594:LOC116486624
uniprot id: A0A6J3CKA5
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

219594:SNX2
gene id: 219594:SNX2
uniprot id: A0A6J3ED66
uniprot id: A0A6J3EI05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Membrane
messages: lamellipodium

219594:NRP1
gene id: 219594:NRP1
uniprot id: A0A6J3CER7
uniprot id: A0A6J3CGE5
uniprot id: A0A6J3CHD1
uniprot id: A0A6J3CJ97
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neuropilin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

219594:FAM187A
gene id: 219594:FAM187A
uniprot id: A0A6J3EAN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM187 family.
messages: Membrane

219594:SETD1B
gene id: 219594:SETD1B
uniprot id: A0A6J3DUM5
names: Subcellular Location Annotation
messages: Chromosome
messages: Nucleus speckle

219594:USP34
gene id: 219594:USP34
uniprot id: A0A6J3CLT7
uniprot id: A0A6J3CNJ5
uniprot id: A0A6J3CPG9
uniprot id: A0A6J3CRS1
names: Similarity
messages: Belongs to the peptidase C19 family.

219594:CHMP5
gene id: 219594:CHMP5
uniprot id: A0A6J3CIK8
names: Similarity
messages: Belongs to the SNF7 family.

219594:DPEP1
gene id: 219594:DPEP1
uniprot id: A0A6J3DJQ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Apical cell membrane
messages: Belongs to the metallo-dependent hydrolases superfamily. Peptidase M19 family.
messages: Cell membrane
messages: Homodimer; disulfide-linked.
messages: Independently of its dipeptidase activity, acts as an adhesion receptor for neutrophil recruitment from bloodstream into inflamed lungs and liver.
messages: Membrane

219594:ZRANB1
gene id: 219594:ZRANB1
uniprot id: A0A6J3D8M1
names: Similarity
messages: Belongs to the peptidase C64 family.

219594:TMEM233
gene id: 219594:TMEM233
uniprot id: A0A6J3DZL2
names: Similarity
messages: Belongs to the CD225/Dispanin family.

219594:LOC116494512
gene id: 219594:LOC116494512
uniprot id: A0A6J3DNV2
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

219594:LAMP2
gene id: 219594:LAMP2
uniprot id: A0A6J3DKA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LAMP family.
messages: Endosome membrane

219594:TIMM10
gene id: 219594:TIMM10
uniprot id: A0A6J3D048
names: Function
messages: Mitochondrial intermembrane chaperone that participates in the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. May also be required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.

219594:ZEB1
gene id: 219594:ZEB1
uniprot id: A0A6J3CIQ6
uniprot id: A0A6J3CK52
uniprot id: A0A6J3CLD3
names: Similarity
messages: Belongs to the delta-EF1/ZFH-1 C2H2-type zinc-finger family.

219594:LOC116497719
gene id: 219594:LOC116497719
uniprot id: A0A6J3E1R4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein arginine deiminase family.
messages: Catalyzes the deimination of arginine residues of proteins.
messages: Cytoplasm

219594:PNPO
gene id: 219594:PNPO
uniprot id: A0A6J3E4N8
names: Function
names: Similarity
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).

219594:AK8
gene id: 219594:AK8
uniprot id: A0A6J3DXP4
uniprot id: A0A6J3DZE7
names: Similarity
messages: Belongs to the adenylate kinase family.

219594:VEPH1
gene id: 219594:VEPH1
uniprot id: A0A6J3DJZ0
names: Similarity
messages: Belongs to the MELT/VEPH family.

219594:LOC116501410
gene id: 219594:LOC116501410
uniprot id: A0A6J3ELU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:EBAG9
gene id: 219594:EBAG9
uniprot id: A0A6J3CK41
names: Function
names: Subcellular Location Annotation
messages: Golgi apparatus membrane
messages: May participate in suppression of cell proliferation and induces apoptotic cell death through activation of interleukin-1-beta converting enzyme (ICE)-like proteases.

219594:CHRNA9
gene id: 219594:CHRNA9
uniprot id: A0A6J3CXL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

219594:LOC116501452
gene id: 219594:LOC116501452
uniprot id: A0A6J3EGQ5
names: Function
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL37 family.
messages: Component of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.

219594:RGS9BP
gene id: 219594:RGS9BP
uniprot id: A0A6J3DPA9
names: Similarity
messages: Belongs to the RGS7BP/RGS9BP family.

219594:LOC116485680
gene id: 219594:LOC116485680
uniprot id: A0A6J3CDJ0
names: Similarity
names: Subunit
messages: Belongs to the avian keratin family.
messages: The avian keratins (F-ker, S-ker, C-ker and B-ker) are a complex mixture of very similar polypeptides.

219594:MRPS24
gene id: 219594:MRPS24
uniprot id: A0A6J3E9N8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Mitochondrion

219594:RAMP3
gene id: 219594:RAMP3
uniprot id: A0A6J3CJZ8
uniprot id: A0A6J3CL79
uniprot id: A0A6J3CN52
names: Similarity
messages: Belongs to the RAMP family.

219594:SLCO2A1
gene id: 219594:SLCO2A1
uniprot id: A0A6J3DEQ3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the organo anion transporter (TC 2.A.60) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Secreted

219594:PPP6C
gene id: 219594:PPP6C
uniprot id: A0A6J3E4N0
names: Similarity
messages: Belongs to the PPP phosphatase family.

219594:DACT1
gene id: 219594:DACT1
uniprot id: A0A6J3CXF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dapper family.
messages: Cytoplasm

219594:MRM2
gene id: 219594:MRM2
uniprot id: A0A6J3DQ14
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.

219594:TFRC
gene id: 219594:TFRC
uniprot id: A0A6J3DHC9
uniprot id: A0A6J3DHX4
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase M28 family. M28B subfamily.
messages: Cell membrane
messages: Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system. Acts as a lipid sensor that regulates mitochondrial fusion by regulating activation of the JNK pathway.
messages: Homodimer; disulfide-linked.
messages: Melanosome
messages: Membrane
messages: Stearoylated.

219594:LOC116499798
gene id: 219594:LOC116499798
uniprot id: A0A6J3EBF5
names: Similarity
names: Subunit
messages: Belongs to the avian keratin family.
messages: The avian keratins (F-ker, S-ker, C-ker and B-ker) are a complex mixture of very similar polypeptides.

219594:TAF2
gene id: 219594:TAF2
uniprot id: A0A6J3CFU8
uniprot id: A0A6J3CHP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF2 family.
messages: Nucleus

219594:LOC116491592
gene id: 219594:LOC116491592
uniprot id: A0A6J3DAT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCG family. Eye pigment precursor importer (TC 3.A.1.204) subfamily.
messages: Cell membrane
messages: Membrane
messages: Mitochondrion membrane

219594:KIF26B
gene id: 219594:KIF26B
uniprot id: A0A6J3CMK2
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

219594:PCMTD2
gene id: 219594:PCMTD2
uniprot id: A0A6J3DTR7
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

219594:TRAF6
gene id: 219594:TRAF6
uniprot id: A0A6J3D4E8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TNF receptor-associated factor family. A subfamily.
messages: Lipid droplet
messages: Nucleus
messages: cell cortex

219594:MAL
gene id: 219594:MAL
uniprot id: A0A6J3CQ57
names: Subcellular Location Annotation
messages: Membrane

219594:DECR2
gene id: 219594:DECR2
uniprot id: A0A6J3DRM0
uniprot id: A0A6J3DVF3
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. 2,4-dienoyl-CoA reductase subfamily.
messages: Monomer, dimer and oligomer.

219594:SEC24A
gene id: 219594:SEC24A
uniprot id: A0A6J3DMJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEC23/SEC24 family. SEC24 subfamily.
messages: COPII-coated vesicle membrane
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: cytosol

219594:MDFIC2
gene id: 219594:MDFIC2
uniprot id: A0A6J3DED6
uniprot id: A0A6J3DIE1
names: Similarity
messages: Belongs to the MDFI family.

219594:EIF4ENIF1
gene id: 219594:EIF4ENIF1
uniprot id: A0A6J3DUI6
uniprot id: A0A6J3DWC2
uniprot id: A0A6J3DYM2
uniprot id: A0A6J3E0F5
names: Subcellular Location Annotation
messages: Cytoplasm

219594:FDFT1
gene id: 219594:FDFT1
uniprot id: A0A6J3CNC1
names: Function
names: Similarity
messages: Belongs to the phytoene/squalene synthase family.
messages: Catalyzes the condensation of 2 farnesyl pyrophosphate (FPP) moieties to form squalene.

219594:MRPL12
gene id: 219594:MRPL12
uniprot id: A0A6J3E0W8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL12 family.

219594:D2HGDH
gene id: 219594:D2HGDH
uniprot id: A0A6J3DGB2
names: Similarity
messages: Belongs to the FAD-binding oxidoreductase/transferase type 4 family.

219594:CRYL1
gene id: 219594:CRYL1
uniprot id: A0A6J3EDB8
names: Similarity
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

219594:LOC116499739
gene id: 219594:LOC116499739
uniprot id: A0A6J3E9U3
names: Similarity
names: Subunit
messages: Belongs to the avian keratin family.
messages: The avian keratins (F-ker, S-ker, C-ker and B-ker) are a complex mixture of very similar polypeptides.

219594:CACNG2
gene id: 219594:CACNG2
uniprot id: A0A6J3DMK8
uniprot id: A0A6J3DPX9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state.

219594:EGFL6
gene id: 219594:EGFL6
uniprot id: A0A6J3DYL3
names: Caution
names: Similarity
messages: Belongs to the nephronectin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:CACHD1
gene id: 219594:CACHD1
uniprot id: A0A6J3DD68
names: Similarity
messages: Belongs to the calcium channel subunit alpha-2/delta family.

219594:ABCB11
gene id: 219594:ABCB11
uniprot id: A0A6J3D3S6
uniprot id: A0A6J3D6V7
uniprot id: A0A6J3D9P5
names: Subcellular Location Annotation
messages: Endosome

219594:HBS1L
gene id: 219594:HBS1L
uniprot id: A0A6J3CRN3
names: Subunit
messages: Interacts with the SKI complex.

219594:P4HA1
gene id: 219594:P4HA1
uniprot id: A0A6J3D5J2
uniprot id: A0A6J3D888
uniprot id: A0A6J3DAY2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P4HA family.
messages: Catalyzes the post-translational formation of 4-hydroxyproline in -Xaa-Pro-Gly- sequences in collagens and other proteins.
messages: Endoplasmic reticulum lumen

219594:IL11RA
gene id: 219594:IL11RA
uniprot id: A0A6J3EFD7
names: Similarity
messages: Belongs to the type I cytokine receptor family. Type 3 subfamily.

219594:CNIH4
gene id: 219594:CNIH4
uniprot id: A0A6J3CVX7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cornichon family.
messages: Membrane

219594:TACC2
gene id: 219594:TACC2
uniprot id: A0A6J3D8Q7
uniprot id: A0A6J3D994
uniprot id: A0A6J3DBF6
uniprot id: A0A6J3DBX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACC family.
messages: Cytoplasm

219594:PDCL2
gene id: 219594:PDCL2
uniprot id: A0A6J3CSZ4
names: Similarity
messages: Belongs to the phosducin family.

219594:CLP1
gene id: 219594:CLP1
uniprot id: A0A6J3D522
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Clp1 family. Clp1 subfamily.
messages: Component of the tRNA splicing endonuclease complex. Component of pre-mRNA cleavage complex II (CF-II).
messages: Nucleus
messages: Polynucleotide kinase that can phosphorylate the 5'-hydroxyl groups of double-stranded RNA (dsRNA), single-stranded RNA (ssRNA), double stranded DNA (dsDNA) and double-stranded DNA:RNA hybrids. dsRNA is phosphorylated more efficiently than dsDNA, and the RNA component of a DNA:RNA hybrid is phosphorylated more efficiently than the DNA component. Appears to have roles in both tRNA splicing and mRNA 3'-end formation. Component of the tRNA splicing endonuclease complex. Phosphorylates the 5'-terminus of the tRNA 3'-exon during tRNA splicing; this phosphorylation event is a prerequisite for the subsequent ligation of the two exon halves and the production of a mature tRNA. Component of the pre-mRNA cleavage complex II (CF-II), which seems to be required for mRNA 3'-end formation. Also phosphorylates the 5'-terminus of exogenously introduced short interfering RNAs (siRNAs), which is a necessary prerequisite for their incorporation into the RNA-induced silencing complex (RISC). However, endogenous siRNAs and microRNAs (miRNAs) that are produced by the cleavage of dsRNA precursors by DICER1 already contain a 5'-phosphate group, so this protein may be dispensible for normal RNA-mediated gene silencing.

219594:LANCL2
gene id: 219594:LANCL2
uniprot id: A0A6J3CKR0
names: Similarity
messages: Belongs to the LanC-like protein family.

219594:NDUFAF7
gene id: 219594:NDUFAF7
uniprot id: A0A6J3CRZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Arginine methyltransferase involved in the assembly or stability of mitochondrial NADH:ubiquinone oxidoreductase complex (complex I).
messages: Belongs to the NDUFAF7 family.
messages: Mitochondrion

219594:PLSCR5
gene id: 219594:PLSCR5
uniprot id: A0A6J3DH96
names: Function
names: Similarity
messages: Belongs to the phospholipid scramblase family.
messages: May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane.

219594:LOC116499809
gene id: 219594:LOC116499809
uniprot id: A0A6J3EET9
names: Similarity
messages: Belongs to the avian keratin family.

219594:LOC116498123
gene id: 219594:LOC116498123
uniprot id: A0A6J3E3P9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCN family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

219594:SAMD4A
gene id: 219594:SAMD4A
uniprot id: A0A6J3D5Q6
uniprot id: A0A6J3D6L7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMAUG family.
messages: Cytoplasm

219594:TIGD5
gene id: 219594:TIGD5
uniprot id: A0A6J3CHV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tigger transposable element derived protein family.
messages: Nucleus

219594:PTPRG
gene id: 219594:PTPRG
uniprot id: A0A6J3DGU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Receptor class 5 subfamily.
messages: Membrane

219594:MPPED2
gene id: 219594:MPPED2
uniprot id: A0A6J3D2Z6
names: Similarity
messages: Belongs to the UPF0046 family.

219594:LLPH
gene id: 219594:LLPH
uniprot id: A0A6J3EPB6
names: Similarity
messages: Belongs to the learning-associated protein family.

219594:VPS11
gene id: 219594:VPS11
uniprot id: A0A6J3E403
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS11 family.
messages: Cytoplasmic vesicle
messages: Early endosome
messages: Late endosome membrane
messages: Lysosome membrane
messages: Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes.
messages: autophagosome
messages: clathrin-coated vesicle

219594:LOC116494243
gene id: 219594:LOC116494243
uniprot id: A0A6J3DQQ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

219594:BCL2
gene id: 219594:BCL2
uniprot id: A0A6J3CL64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Bcl-2 family.
messages: Cytoplasm
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Mitochondrion outer membrane
messages: Nucleus membrane

219594:GPR61
gene id: 219594:GPR61
uniprot id: A0A6J3E642
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

219594:ANAPC13
gene id: 219594:ANAPC13
uniprot id: A0A6J3DFJ3
names: Function
names: Similarity
messages: Belongs to the APC13 family.
messages: Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.

219594:STK10
gene id: 219594:STK10
uniprot id: A0A6J3DTS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.
messages: Cell membrane

219594:LOC116500320
gene id: 219594:LOC116500320
uniprot id: A0A6J3EGI8
names: Subcellular Location Annotation
messages: Membrane

219594:GPRC5B
gene id: 219594:GPRC5B
uniprot id: A0A6J3DPI7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

219594:ANTXR1
gene id: 219594:ANTXR1
uniprot id: A0A6J3E8B6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATR family.
messages: Membrane

219594:SYNDIG1L
gene id: 219594:SYNDIG1L
uniprot id: A0A6J3D254
uniprot id: A0A6J3D4Y1
uniprot id: A0A6J3D753
names: Similarity
messages: Belongs to the CD225/Dispanin family.

219594:ST13
gene id: 219594:ST13
uniprot id: A0A6J3D9R4
names: Similarity
messages: Belongs to the FAM10 family.

219594:TRAP1
gene id: 219594:TRAP1
uniprot id: A0A6J3DUW8
names: Similarity
messages: Belongs to the heat shock protein 90 family.

219594:TEX261
gene id: 219594:TEX261
uniprot id: A0A6J3CZS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SVP26 family.
messages: Membrane

219594:LOC116488810
gene id: 219594:LOC116488810
uniprot id: A0A6J3CWU1
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

219594:SPIRE2
gene id: 219594:SPIRE2
uniprot id: A0A6J3DME2
uniprot id: A0A6J3DR20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the spire family.
messages: Cell membrane
messages: Cytoplasmic vesicle membrane
messages: Membrane
messages: cytoskeleton

219594:RPL3L
gene id: 219594:RPL3L
uniprot id: A0A6J3DVG6
names: Similarity
messages: Belongs to the universal ribosomal protein uL3 family.

219594:CACNB3
gene id: 219594:CACNB3
uniprot id: A0A6J3EAD2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calcium channel beta subunit family.
messages: Cytoplasm

219594:LOC116496878
gene id: 219594:LOC116496878
uniprot id: A0A6J3E1Y4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SURF1 family.
messages: Mitochondrion inner membrane
messages: Probably involved in the biogenesis of the COX complex.

219594:FAM133B
gene id: 219594:FAM133B
uniprot id: A0A6J3CGD3
names: Similarity
messages: Belongs to the FAM133 family.

219594:ETV7
gene id: 219594:ETV7
uniprot id: A0A6J3E6I9
uniprot id: A0A6J3E820
uniprot id: A0A6J3EB24
uniprot id: A0A6J3ED68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

219594:LOC116502098
gene id: 219594:LOC116502098
uniprot id: A0A6J3EQQ8
names: Similarity
messages: Belongs to the ENTR1 family.

219594:WDR18
gene id: 219594:WDR18
uniprot id: A0A6J3ECJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat IPI3/WDR18 family.
messages: Dynein axonemal particle
messages: nucleolus
messages: nucleoplasm

219594:UCHL1
gene id: 219594:UCHL1
uniprot id: A0A6J3CYP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C12 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

219594:USP13
gene id: 219594:USP13
uniprot id: A0A6J3DJ29
names: Similarity
messages: Belongs to the peptidase C19 family.

219594:BPNT1
gene id: 219594:BPNT1
uniprot id: A0A6J3CV31
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

219594:LOC116500021
gene id: 219594:LOC116500021
uniprot id: A0A6J3EAU5
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

219594:KCNS1
gene id: 219594:KCNS1
uniprot id: A0A6J3DYJ4
names: Subcellular Location Annotation
messages: Membrane

219594:LOC116495431
gene id: 219594:LOC116495431
uniprot id: A0A6J3DSX7
names: Similarity
messages: Belongs to the tubulin family.

219594:LRP5
gene id: 219594:LRP5
uniprot id: A0A6J3D084
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LDLR family.
messages: Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes.
messages: Homodimer; disulfide-linked. Forms phosphorylated oligomer aggregates on Wnt-signaling.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:PKIG
gene id: 219594:PKIG
uniprot id: A0A6J3DY81
names: Function
names: Similarity
messages: Belongs to the PKI family.
messages: Extremely potent competitive inhibitor of cAMP-dependent protein kinase activity, this protein interacts with the catalytic subunit of the enzyme after the cAMP-induced dissociation of its regulatory chains.

219594:LOC116485434
gene id: 219594:LOC116485434
uniprot id: A0A6J3CIL0
names: Similarity
names: Subunit
messages: Belongs to the avian keratin family.
messages: The avian keratins (F-ker, S-ker, C-ker and B-ker) are a complex mixture of very similar polypeptides.

219594:SEMA5B
gene id: 219594:SEMA5B
uniprot id: A0A6J3D5I5
uniprot id: A0A6J3D7R6
uniprot id: A0A6J3D8K4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:SLC10A1
gene id: 219594:SLC10A1
uniprot id: A0A6J3D0C1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bile acid:sodium symporter (BASS) (TC 2.A.28) family.
messages: Membrane

219594:LOC116488853
gene id: 219594:LOC116488853
uniprot id: A0A6J3CUC9
uniprot id: A0A6J3CWM8
uniprot id: A0A6J3CX02
names: Similarity
names: Subunit
messages: Homooctamer.
messages: In the C-terminal section; belongs to the AIR carboxylase family. Class II subfamily.
messages: In the N-terminal section; belongs to the SAICAR synthetase family.

219594:FOXD2
gene id: 219594:FOXD2
uniprot id: A0A6J3DCV0
names: Subcellular Location Annotation
messages: Nucleus

219594:CAMK1
gene id: 219594:CAMK1
uniprot id: A0A6J3DHE4
names: Similarity
messages: Belongs to the protein kinase superfamily.

219594:SLAIN1
gene id: 219594:SLAIN1
uniprot id: A0A6J3EK60
names: Similarity
messages: Belongs to the SLAIN motif-containing family.

219594:LOC116495036
gene id: 219594:LOC116495036
uniprot id: A0A6J3DT21
names: Subcellular Location Annotation
messages: Secreted

219594:LOC116494133
gene id: 219594:LOC116494133
uniprot id: A0A6J3DQA9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

219594:ATE1
gene id: 219594:ATE1
uniprot id: A0A6J3D6D2
uniprot id: A0A6J3D933
uniprot id: A0A6J3DBU6
uniprot id: A0A6J3DCA9
names: Function
names: Similarity
messages: Belongs to the R-transferase family.
messages: Involved in the post-translational conjugation of arginine to the N-terminal aspartate or glutamate of a protein. This arginylation is required for degradation of the protein via the ubiquitin pathway.

219594:LOC116499753
gene id: 219594:LOC116499753
uniprot id: A0A6J3EBA2
names: Similarity
names: Subunit
messages: Belongs to the avian keratin family.
messages: The avian keratins (F-ker, S-ker, C-ker and B-ker) are a complex mixture of very similar polypeptides.

219594:DICER1
gene id: 219594:DICER1
uniprot id: A0A6J3CZE0
names: Function
names: Similarity
messages: Belongs to the helicase family. Dicer subfamily.
messages: Double-stranded RNA (dsRNA) endoribonuclease playing a central role in short dsRNA-mediated post-transcriptional gene silencing. Cleaves naturally occurring long dsRNAs and short hairpin pre-microRNAs (miRNA) into fragments of twenty-one to twenty-three nucleotides with 3' overhang of two nucleotides, producing respectively short interfering RNAs (siRNA) and mature microRNAs. SiRNAs and miRNAs serve as guide to direct the RNA-induced silencing complex (RISC) to complementary RNAs to degrade them or prevent their translation. Gene silencing mediated by siRNAs, also called RNA interference, controls the elimination of transcripts from mobile and repetitive DNA elements of the genome but also the degradation of exogenous RNA of viral origin for instance. The miRNA pathway on the other side is a mean to specifically regulate the expression of target genes.

219594:RRM2B
gene id: 219594:RRM2B
uniprot id: A0A6J3CHL3
names: Cofactor
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.

219594:CYGB
gene id: 219594:CYGB
uniprot id: A0A6J3DXQ1
names: Similarity
messages: Belongs to the globin family.

219594:NSUN5
gene id: 219594:NSUN5
uniprot id: A0A6J3DZF9
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:SELENOM
gene id: 219594:SELENOM
uniprot id: A0A6J3DYA6
names: Similarity
messages: Belongs to the selenoprotein M/F family.

219594:MIEF1
gene id: 219594:MIEF1
uniprot id: A0A6J3DXM1
names: Subcellular Location Annotation
messages: Membrane
messages: Mitochondrion outer membrane

219594:MED1
gene id: 219594:MED1
uniprot id: A0A6J3E625
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mediator complex subunit 1 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Nucleus

219594:TM9SF2
gene id: 219594:TM9SF2
uniprot id: A0A6J3DM44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family.
messages: Membrane

219594:TASOR
gene id: 219594:TASOR
uniprot id: A0A6J3DEI1
uniprot id: A0A6J3DEI4
uniprot id: A0A6J3DII6
uniprot id: A0A6J3DK43
uniprot id: A0A6J3DK48
uniprot id: A0A6J3DKN7
names: Similarity
messages: Belongs to the TASOR family.

219594:BUD31
gene id: 219594:BUD31
uniprot id: A0A6J3DRN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BUD31 (G10) family.
messages: Nucleus

219594:KLHL21
gene id: 219594:KLHL21
uniprot id: A0A6J3E7W1
names: Subcellular Location Annotation
messages: spindle

219594:MAL2
gene id: 219594:MAL2
uniprot id: A0A6J3CBU1
names: Subcellular Location Annotation
messages: Membrane

219594:TMEM88B
gene id: 219594:TMEM88B
uniprot id: A0A6J3E5S6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM88 family.
messages: Membrane

219594:FAM83G
gene id: 219594:FAM83G
uniprot id: A0A6J3DV97
names: Similarity
messages: Belongs to the FAM83 family.

219594:LOC116487460
gene id: 219594:LOC116487460
uniprot id: A0A6J3CMT1
names: Subcellular Location Annotation
messages: Membrane

219594:CD40LG
gene id: 219594:CD40LG
uniprot id: A0A6J3DP37
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a ligand for integrins, specifically ITGA5:ITGB1 and ITGAV:ITGB3; both integrins and the CD40 receptor are required for activation of CD40-CD40LG signaling, which have cell-type dependent effects, such as B-cell activation, NF-kappa-B signaling and anti-apoptotic signaling.
messages: Belongs to the tumor necrosis factor family.
messages: Cell surface
messages: Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching.
messages: Homotrimer.

219594:KIFC3
gene id: 219594:KIFC3
uniprot id: A0A6J3DR77
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

219594:TRMT5
gene id: 219594:TRMT5
uniprot id: A0A6J3D1U9
uniprot id: A0A6J3D4D4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRM5 / TYW2 family.
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM5/TYW2 family.
messages: Cytoplasm
messages: Mitochondrion matrix
messages: Monomer.
messages: Nucleus
messages: Specifically methylates the N1 position of guanosine-37 in various cytoplasmic and mitochondrial tRNAs. Methylation is not dependent on the nature of the nucleoside 5' of the target nucleoside. This is the first step in the biosynthesis of wybutosine (yW), a modified base adjacent to the anticodon of tRNAs and required for accurate decoding.

219594:WDR76
gene id: 219594:WDR76
uniprot id: A0A6J3DLJ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the WD repeat DDB2/WDR76 family.
messages: Interacts with CUL4A and/or CUL4B.
messages: Specifically binds 5-hydroxymethylcytosine (5hmC), suggesting that it acts as a specific reader of 5hmC.

219594:LITAF
gene id: 219594:LITAF
uniprot id: A0A6J3DQK8
uniprot id: A0A6J3DVU9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDIP1/LITAF family.
messages: Lysosome membrane
messages: Membrane

219594:COPG1
gene id: 219594:COPG1
uniprot id: A0A6J3DIX2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the COPG family.
messages: COPI-coated vesicle membrane
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Membrane
messages: Oligomeric complex.
messages: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.

219594:DGKH
gene id: 219594:DGKH
uniprot id: A0A6J3D3E7
uniprot id: A0A6J3D3I0
uniprot id: A0A6J3D8M9
uniprot id: A0A6J3D8Q5
uniprot id: A0A6J3D9B7
names: Similarity
messages: Belongs to the eukaryotic diacylglycerol kinase family.

219594:IMPDH2
gene id: 219594:IMPDH2
uniprot id: A0A6J3DI83
uniprot id: A0A6J3DJI5
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.
messages: Nucleus

219594:SOX9
gene id: 219594:SOX9
uniprot id: A0A6J3DZQ7
names: Subcellular Location Annotation
messages: Nucleus

219594:HTR1D
gene id: 219594:HTR1D
uniprot id: A0A6J3EA52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:PLA2G15
gene id: 219594:PLA2G15
uniprot id: A0A6J3DQC6
names: Similarity
messages: Belongs to the AB hydrolase superfamily. Lipase family.

219594:IMPG1
gene id: 219594:IMPG1
uniprot id: A0A6J3CQP2
names: Subcellular Location Annotation
messages: interphotoreceptor matrix

219594:PTPN13
gene id: 219594:PTPN13
uniprot id: A0A6J3CVV7
uniprot id: A0A6J3CVW3
uniprot id: A0A6J3CY60
uniprot id: A0A6J3CYH3
uniprot id: A0A6J3CYH6
uniprot id: A0A6J3D0R7
uniprot id: A0A6J3D1X1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class subfamily.
messages: Regulates negatively FAS-induced apoptosis and NGFR-mediated pro-apoptotic signaling.
messages: cytoskeleton

219594:LOC116492076
gene id: 219594:LOC116492076
uniprot id: A0A6J3DG79
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:SLC30A3
gene id: 219594:SLC30A3
uniprot id: A0A6J3CQP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
messages: Membrane

219594:PARD3
gene id: 219594:PARD3
uniprot id: A0A6J3CJG1
uniprot id: A0A6J3CJG6
uniprot id: A0A6J3CJH0
uniprot id: A0A6J3CJH6
uniprot id: A0A6J3CJI1
uniprot id: A0A6J3CKX0
uniprot id: A0A6J3CKX5
uniprot id: A0A6J3CKY1
uniprot id: A0A6J3CKY7
uniprot id: A0A6J3CM37
uniprot id: A0A6J3CM44
uniprot id: A0A6J3CM53
uniprot id: A0A6J3CP26
uniprot id: A0A6J3CP31
uniprot id: A0A6J3CP37
uniprot id: A0A6J3CP40
uniprot id: A0A6J3CQE5
uniprot id: A0A6J3CQF0
uniprot id: A0A6J3CQF5
uniprot id: A0A6J3CQG0
uniprot id: A0A6J3CQG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAR3 family.
messages: Cell junction
messages: Endomembrane system

219594:LOC116486723
gene id: 219594:LOC116486723
uniprot id: A0A6J3CKR1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thrombospondin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular space

219594:LOC116502094
gene id: 219594:LOC116502094
uniprot id: A0A6J3EPB9
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

219594:LOC116486763
gene id: 219594:LOC116486763
uniprot id: A0A6J3CM22
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

219594:TPST1
gene id: 219594:TPST1
uniprot id: A0A6J3E4K0
uniprot id: A0A6J3E4L2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein sulfotransferase family.
messages: Catalyzes the O-sulfation of tyrosine residues within acidic motifs of polypeptides, using 3'-phosphoadenylyl sulfate (PAPS) as cosubstrate.
messages: Golgi apparatus membrane

219594:RAB11FIP4
gene id: 219594:RAB11FIP4
uniprot id: A0A6J3DVK1
uniprot id: A0A6J3DXF5
names: Subcellular Location Annotation
messages: Cleavage furrow
messages: Endosome membrane
messages: Membrane
messages: Midbody
messages: Recycling endosome membrane

219594:GADD45G
gene id: 219594:GADD45G
uniprot id: A0A6J3EIV2
names: Similarity
messages: Belongs to the GADD45 family.

219594:SYS1
gene id: 219594:SYS1
uniprot id: A0A6J3DU18
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SYS1 family.
messages: Golgi apparatus membrane
messages: Interacts with ARFRP1.
messages: Involved in protein trafficking. May serve as a receptor for ARFRP1.
messages: Membrane

219594:MYO9B
gene id: 219594:MYO9B
uniprot id: A0A6J3E6X8
uniprot id: A0A6J3E8F2
uniprot id: A0A6J3EBG2
uniprot id: A0A6J3EBZ2
uniprot id: A0A6J3EDM3
uniprot id: A0A6J3EDM8
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

219594:NUP133
gene id: 219594:NUP133
uniprot id: A0A6J3CPV9
uniprot id: A0A6J3CVZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleoporin Nup133 family.
messages: nuclear pore complex

219594:SEMA5A
gene id: 219594:SEMA5A
uniprot id: A0A6J3CCD3
uniprot id: A0A6J3CF10
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:LOC116485375
gene id: 219594:LOC116485375
uniprot id: A0A6J3CC42
names: Similarity
names: Subunit
messages: Belongs to the avian keratin family.
messages: The avian keratins (F-ker, S-ker, C-ker and B-ker) are a complex mixture of very similar polypeptides.

219594:FYN
gene id: 219594:FYN
uniprot id: A0A6J3CRH3
uniprot id: A0A6J3CTT7
uniprot id: A0A6J3CXN7
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

219594:DOLK
gene id: 219594:DOLK
uniprot id: A0A6J3E4T5
names: Similarity
messages: Belongs to the polyprenol kinase family.

219594:LOC116496924
gene id: 219594:LOC116496924
uniprot id: A0A6J3E254
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POU transcription factor family.
messages: Nucleus

219594:DISP3
gene id: 219594:DISP3
uniprot id: A0A6J3E0U9
uniprot id: A0A6J3E5U0
names: Subcellular Location Annotation
messages: Membrane

219594:SIRT4
gene id: 219594:SIRT4
uniprot id: A0A6J3DX30
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sirtuin family. Class II subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Mitochondrion matrix
messages: NAD-dependent protein deacylase. Catalyzes the NAD-dependent hydrolysis of acyl groups from lysine residues.

219594:TOPAZ1
gene id: 219594:TOPAZ1
uniprot id: A0A6J3CGM5
names: Function
names: Subcellular Location Annotation
messages: Important for normal spermatogenesis and male fertility. Specifically required for progression to the post-meiotic stages of spermatocyte development. Seems to be necessary for normal expression levels of a number of testis-expressed gene transcripts, although its role in this process is unclear.
messages: cytosol

219594:SPTY2D1
gene id: 219594:SPTY2D1
uniprot id: A0A6J3D6U3
names: Similarity
messages: Belongs to the SPT2 family.

219594:LOC116500141
gene id: 219594:LOC116500141
uniprot id: A0A6J3EBA4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:TRAF4
gene id: 219594:TRAF4
uniprot id: A0A6J3E196
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TNF receptor-associated factor family.
messages: Cytoplasm

219594:LOC116493976
gene id: 219594:LOC116493976
uniprot id: A0A6J3DQF0
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

219594:GGNBP2
gene id: 219594:GGNBP2
uniprot id: A0A6J3E1C5
uniprot id: A0A6J3E603
names: Function
messages: May be involved in spermatogenesis.

219594:IRX5
gene id: 219594:IRX5
uniprot id: A0A6J3DM18
uniprot id: A0A6J3DPZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/IRO homeobox family.
messages: Nucleus

219594:TMEM255A
gene id: 219594:TMEM255A
uniprot id: A0A6J3DNT5
uniprot id: A0A6J3DQP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM255 family.
messages: Membrane

219594:TRIM36
gene id: 219594:TRIM36
uniprot id: A0A6J3EDF3
uniprot id: A0A6J3EET5
uniprot id: A0A6J3EI97
uniprot id: A0A6J3EIL2
names: Subcellular Location Annotation
messages: cytoskeleton

219594:LIMD1
gene id: 219594:LIMD1
uniprot id: A0A6J3CLC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the zyxin/ajuba family.
messages: Cytoplasm
messages: Nucleus

219594:LOC116501295
gene id: 219594:LOC116501295
uniprot id: A0A6J3ELC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta type-B retroviral polymerase family. HERV class-II K(HML-2) pol subfamily.
messages: Virion

219594:MAF
gene id: 219594:MAF
uniprot id: A0A6J3DPJ1
names: Similarity
messages: Belongs to the bZIP family. Maf subfamily.

219594:ELMO1
gene id: 219594:ELMO1
uniprot id: A0A6J3CKI3
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Acts in association with DOCK1 and CRK. Was initially proposed to be required in complex with DOCK1 to activate Rac Rho small GTPases. May enhance the guanine nucleotide exchange factor (GEF) activity of DOCK1.

219594:IP6K1
gene id: 219594:IP6K1
uniprot id: A0A6J3DL47
names: Similarity
messages: Belongs to the inositol phosphokinase (IPK) family.

219594:BRI3
gene id: 219594:BRI3
uniprot id: A0A6J3DVX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BRI3 family.
messages: Membrane
messages: perinuclear region

219594:KCNN3
gene id: 219594:KCNN3
uniprot id: A0A6J3E9Q7
names: Subcellular Location Annotation
messages: Membrane

219594:ERC2
gene id: 219594:ERC2
uniprot id: A0A6J3DI68
names: Subcellular Location Annotation
messages: Cytoplasm

219594:NPY
gene id: 219594:NPY
uniprot id: A0A6J3CII4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NPY family.
messages: Secreted

219594:LOC116502111
gene id: 219594:LOC116502111
uniprot id: A0A6J3EJ14
names: Similarity
messages: Belongs to the Arg-specific ADP-ribosyltransferase family.

219594:ALG11
gene id: 219594:ALG11
uniprot id: A0A6J3EP94
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily.
messages: Endoplasmic reticulum membrane
messages: Required for N-linked oligosaccharide assembly.

219594:CTH
gene id: 219594:CTH
uniprot id: A0A6J3DCY1
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

219594:CAV1
gene id: 219594:CAV1
uniprot id: A0A6J3DT32
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the caveolin family.
messages: Cell membrane
messages: Golgi apparatus membrane
messages: May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity.
messages: Membrane
messages: Membrane raft
messages: caveola

219594:NDUFB5
gene id: 219594:NDUFB5
uniprot id: A0A6J3DJ67
names: Function
names: Similarity
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFB5 subunit family.
messages: Complex I is composed of 45 different subunits.

219594:COPE
gene id: 219594:COPE
uniprot id: A0A6J3ECF2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the COPE family.
messages: Cytoplasm
messages: Membrane
messages: Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.
messages: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. The coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.

219594:IAPP
gene id: 219594:IAPP
uniprot id: A0A6J3DZG1
names: Similarity
messages: Belongs to the calcitonin family.

219594:STK11IP
gene id: 219594:STK11IP
uniprot id: A0A6J3DAH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STK11IP family.
messages: Cytoplasm

219594:SLC17A8
gene id: 219594:SLC17A8
uniprot id: A0A6J3EQ82
names: Subcellular Location Annotation
messages: Membrane

219594:LOC116498348
gene id: 219594:LOC116498348
uniprot id: A0A6J3E9A4
names: Similarity
names: Subunit
messages: Belongs to the avian keratin family.
messages: The avian keratins (F-ker, S-ker, C-ker and B-ker) are a complex mixture of very similar polypeptides.

219594:LOC116498551
gene id: 219594:LOC116498551
uniprot id: A0A6J3EA55
names: Similarity
names: Subunit
messages: Belongs to the avian keratin family.
messages: The avian keratins (F-ker, S-ker, C-ker and B-ker) are a complex mixture of very similar polypeptides.

219594:DESI1
gene id: 219594:DESI1
uniprot id: A0A6J3D8D3
names: Similarity
messages: Belongs to the DeSI family.

219594:BMP7
gene id: 219594:BMP7
uniprot id: A0A6J3DXX3
names: Similarity
messages: Belongs to the TGF-beta family.

219594:ILK
gene id: 219594:ILK
uniprot id: A0A6J3EI88
names: Subcellular Location Annotation
messages: focal adhesion
messages: lamellipodium
messages: sarcomere

219594:PDIA6
gene id: 219594:PDIA6
uniprot id: A0A6J3CS38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein disulfide isomerase family.
messages: Endoplasmic reticulum lumen
messages: Melanosome

219594:LOC116485367
gene id: 219594:LOC116485367
uniprot id: A0A6J3CGJ8
names: Similarity
messages: Belongs to the serpin family.

219594:TFAP2C
gene id: 219594:TFAP2C
uniprot id: A0A6J3DXJ1
names: Similarity
messages: Belongs to the AP-2 family.

219594:LOC116491924
gene id: 219594:LOC116491924
uniprot id: A0A6J3DCE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FMO family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Microsome membrane

219594:LOC116500943
gene id: 219594:LOC116500943
uniprot id: A0A6J3EEP5
uniprot id: A0A6J3EG45
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the organo anion transporter (TC 2.A.60) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Secreted

219594:ITPR2
gene id: 219594:ITPR2
uniprot id: A0A6J3CSN9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the InsP3 receptor family.
messages: Endoplasmic reticulum membrane
messages: Homotetramer.
messages: Membrane
messages: Receptor for inositol 1,4,5-trisphosphate, a second messenger that mediates the release of intracellular calcium.
messages: The receptor contains a calcium channel in its C-terminal extremity. Its large N-terminal cytoplasmic region has the ligand-binding site in the N-terminus and modulatory sites in the middle portion immediately upstream of the channel region.

219594:LRP2
gene id: 219594:LRP2
uniprot id: A0A6J3D8R4
names: Caution
names: Similarity
messages: Belongs to the LDLR family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:PRPF38B
gene id: 219594:PRPF38B
uniprot id: A0A6J3DFZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRP38 family.
messages: May be required for pre-mRNA splicing.
messages: Nucleus

219594:CDT1
gene id: 219594:CDT1
uniprot id: A0A6J3DPP0
names: Similarity
messages: Belongs to the Cdt1 family.

219594:BCAR1
gene id: 219594:BCAR1
uniprot id: A0A6J3DQ82
uniprot id: A0A6J3DQW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAS family.
messages: focal adhesion

219594:COPS7A
gene id: 219594:COPS7A
uniprot id: A0A6J3DBQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSN7/EIF3M family. CSN7 subfamily.
messages: Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53, JUN, I-kappa-B-alpha/NFKBIA, ITPK1 and IRF8/ICSBP, possibly via its association with CK2 and PKD kinases. CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, respectively.
messages: Cytoplasm
messages: Nucleus

219594:SSTR3
gene id: 219594:SSTR3
uniprot id: A0A6J3E909
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:FAM163B
gene id: 219594:FAM163B
uniprot id: A0A6J3E285
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM163 family.
messages: Membrane

219594:NEK6
gene id: 219594:NEK6
uniprot id: A0A6J3DZ82
names: Similarity
messages: Belongs to the protein kinase superfamily.

219594:LOC116489327
gene id: 219594:LOC116489327
uniprot id: A0A6J3CZ76
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

219594:PRR15L
gene id: 219594:PRR15L
uniprot id: A0A6J3EA91
names: Similarity
messages: Belongs to the PRR15 family.

219594:ITGA1
gene id: 219594:ITGA1
uniprot id: A0A6J3EE45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

219594:RDH10
gene id: 219594:RDH10
uniprot id: A0A6J3CMT8
uniprot id: A0A6J3CPA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Microsome membrane

219594:C9
gene id: 219594:C9
uniprot id: A0A6J3EJE7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complement C6/C7/C8/C9 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Secreted
messages: Target cell membrane

219594:LOC116497691
gene id: 219594:LOC116497691
uniprot id: A0A6J3E1L7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF9 family. CENP-S/MHF1 subfamily.
messages: Nucleus
messages: kinetochore

219594:C5H11orf58
gene id: 219594:C5H11orf58
uniprot id: A0A6J3D0Z3
names: Similarity
messages: Belongs to the SMAP family.

219594:SUV39H2
gene id: 219594:SUV39H2
uniprot id: A0A6J3EJS2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. Suvar3-9 subfamily.
messages: Nucleus
messages: centromere

219594:SMIM12
gene id: 219594:SMIM12
uniprot id: A0A6J3E3G9
names: Similarity
messages: Belongs to the SMIM12 family.

219594:SORCS3
gene id: 219594:SORCS3
uniprot id: A0A6J3D6R9
names: Similarity
messages: Belongs to the VPS10-related sortilin family. SORCS subfamily.

219594:LOC116498600
gene id: 219594:LOC116498600
uniprot id: A0A6J3E5B3
names: Domain
names: Function
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
messages: Converts 1-acyl-sn-glycerol-3-phosphate (lysophosphatidic acid or LPA) into 1,2-diacyl-sn-glycerol-3-phosphate (phosphatidic acid or PA) by incorporating an acyl moiety at the sn-2 position of the glycerol backbone.
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

219594:SLC35B3
gene id: 219594:SLC35B3
uniprot id: A0A6J3CE69
uniprot id: A0A6J3CF67
uniprot id: A0A6J3CH15
uniprot id: A0A6J3CIT7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide-sugar transporter family. SLC35B subfamily.
messages: Membrane

219594:LOC116485585
gene id: 219594:LOC116485585
uniprot id: A0A6J3CEW4
names: Function
messages: The products of the Gag polyproteins of infectious retroviruses perform highly complex orchestrated tasks during the assembly, budding, maturation, and infection stages of the viral replication cycle. During viral assembly, the proteins form membrane associations and self-associations that ultimately result in budding of an immature virion from the infected cell. Gag precursors also function during viral assembly to selectively bind and package two plus strands of genomic RNA. Endogenous Gag proteins may have kept, lost or modified their original function during evolution.

219594:TSHZ1
gene id: 219594:TSHZ1
uniprot id: A0A6J3CJE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the teashirt C2H2-type zinc-finger protein family.
messages: Nucleus

219594:C2H5orf22
gene id: 219594:C2H5orf22
uniprot id: A0A6J3CPP7
names: Similarity
messages: Belongs to the UPF0489 family.

219594:PLN
gene id: 219594:PLN
uniprot id: A0A6J3CRC1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phospholamban family.
messages: Endoplasmic reticulum membrane
messages: Homopentamer.
messages: Membrane
messages: Mitochondrion membrane
messages: Reversibly inhibits the activity of ATP2A2 in cardiac sarcoplasmic reticulum by decreasing the apparent affinity of the ATPase for Ca(2+). Modulates the contractility of the heart muscle in response to physiological stimuli via its effects on ATP2A2. Modulates calcium re-uptake during muscle relaxation and plays an important role in calcium homeostasis in the heart muscle. The degree of ATP2A2 inhibition depends on the oligomeric state of PLN.
messages: Sarcoplasmic reticulum membrane

219594:CTNND2
gene id: 219594:CTNND2
uniprot id: A0A6J3CG27
uniprot id: A0A6J3CHP2
uniprot id: A0A6J3CIP7
uniprot id: A0A6J3CIQ2
uniprot id: A0A6J3CKM0
uniprot id: A0A6J3CKM5
uniprot id: A0A6J3CMB7
names: Similarity
messages: Belongs to the beta-catenin family.

219594:SLA
gene id: 219594:SLA
uniprot id: A0A6J3CIA8
names: Subcellular Location Annotation
messages: Cytoplasm

219594:LOC116486267
gene id: 219594:LOC116486267
uniprot id: A0A6J3CGX0
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

219594:NUDCD1
gene id: 219594:NUDCD1
uniprot id: A0A6J3CFW3
uniprot id: A0A6J3CGV1
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

219594:DRAM1
gene id: 219594:DRAM1
uniprot id: A0A6J3DTW1
names: Subcellular Location Annotation
messages: Membrane

219594:ARHGEF11
gene id: 219594:ARHGEF11
uniprot id: A0A6J3EEG0
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Membrane

219594:NEUROD1
gene id: 219594:NEUROD1
uniprot id: A0A6J3D853
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

219594:ADRA1D
gene id: 219594:ADRA1D
uniprot id: A0A6J3D1E4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Interacts with FLNA (via filamin repeat 21); increases PKA-mediated phosphorylation of FLNA.
messages: Membrane
messages: This alpha-adrenergic receptor mediates its effect through the influx of extracellular calcium.

219594:DYNLL2
gene id: 219594:DYNLL2
uniprot id: A0A6J3E5F8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dynein light chain family.
messages: cytoskeleton

219594:LPL
gene id: 219594:LPL
uniprot id: A0A6J3EFG5
uniprot id: A0A6J3EKM5
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. Lipase family.
messages: Cell membrane
messages: Homodimer. Interacts with APOC2; the interaction activates LPL activity in the presence of lipids.
messages: Key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage. Mediates margination of triglyceride-rich lipoprotein particles in capillaries. Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted
messages: Tyrosine nitration after lipopolysaccharide (LPS) challenge down-regulates the lipase activity.
messages: extracellular matrix

219594:LOC116501303
gene id: 219594:LOC116501303
uniprot id: A0A6J3EMU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:NT5DC2
gene id: 219594:NT5DC2
uniprot id: A0A6J3DLR6
names: Cofactor
names: Similarity
messages: Belongs to the 5'(3')-deoxyribonucleotidase family.
messages: Binds 1 Mg(2+) ion per subunit.

219594:BRINP2
gene id: 219594:BRINP2
uniprot id: A0A6J3DB05
names: Similarity
messages: Belongs to the BRINP family.

219594:LOC116498581
gene id: 219594:LOC116498581
uniprot id: A0A6J3EA97
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

219594:CDK5RAP3
gene id: 219594:CDK5RAP3
uniprot id: A0A6J3EB82
names: Similarity
messages: Belongs to the CDK5RAP3 family.

219594:NEU3
gene id: 219594:NEU3
uniprot id: A0A6J3EHN8
names: Similarity
messages: Belongs to the glycosyl hydrolase 33 family.

219594:HMBS
gene id: 219594:HMBS
uniprot id: A0A6J3E3Y0
uniprot id: A0A6J3E8W9
names: Similarity
messages: Belongs to the HMBS family.

219594:LOC116495464
gene id: 219594:LOC116495464
uniprot id: A0A6J3DWY5
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

219594:CCT3
gene id: 219594:CCT3
uniprot id: A0A6J3EB99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCP-1 chaperonin family.
messages: Cytoplasm

219594:CDK3
gene id: 219594:CDK3
uniprot id: A0A6J3DY55
names: Similarity
messages: Belongs to the protein kinase superfamily.

219594:LOC116491360
gene id: 219594:LOC116491360
uniprot id: A0A6J3D6T6
names: Caution
names: Similarity
messages: Belongs to the DMBT1 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:CHDH
gene id: 219594:CHDH
uniprot id: A0A6J3DJL1
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

219594:TBX5
gene id: 219594:TBX5
uniprot id: A0A6J3DYW5
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

219594:ENDOG
gene id: 219594:ENDOG
uniprot id: A0A6J3DZL0
names: Similarity
messages: Belongs to the DNA/RNA non-specific endonuclease family.

219594:CRYBB1
gene id: 219594:CRYBB1
uniprot id: A0A6J3E046
names: Function
names: Similarity
names: Subunit
messages: Belongs to the beta/gamma-crystallin family.
messages: Crystallins are the dominant structural components of the vertebrate eye lens.
messages: Homo/heterodimer, or complexes of higher-order. The structure of beta-crystallin oligomers seems to be stabilized through interactions between the N-terminal arms.

219594:SLC25A26
gene id: 219594:SLC25A26
uniprot id: A0A6J3DJP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

219594:MTCH2
gene id: 219594:MTCH2
uniprot id: A0A6J3D151
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

219594:POLR1A
gene id: 219594:POLR1A
uniprot id: A0A6J3CZX4
names: Function
names: Similarity
messages: Belongs to the RNA polymerase beta' chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.

219594:ZC3HC1
gene id: 219594:ZC3HC1
uniprot id: A0A6J3EQR3
uniprot id: A0A6J3ES06
names: Subcellular Location Annotation
messages: Nucleus

219594:LOC116502086
gene id: 219594:LOC116502086
uniprot id: A0A6J3EKC4
names: Similarity
messages: Belongs to the folate receptor family.

219594:NPY1R
gene id: 219594:NPY1R
uniprot id: A0A6J3CY44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:SLC46A3
gene id: 219594:SLC46A3
uniprot id: A0A6J3ELB5
names: Subcellular Location Annotation
messages: Membrane

219594:SLC16A7
gene id: 219594:SLC16A7
uniprot id: A0A6J3CQU0
names: Similarity
names: Subcellular Location Annotation
messages: Basolateral cell membrane
messages: Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.
messages: Cytoplasm
messages: Membrane

219594:TMEM135
gene id: 219594:TMEM135
uniprot id: A0A6J3D230
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM135 family.
messages: Membrane
messages: Peroxisome membrane

219594:MDFI
gene id: 219594:MDFI
uniprot id: A0A6J3EBR5
names: Similarity
messages: Belongs to the MDFI family.

219594:LOC116497943
gene id: 219594:LOC116497943
uniprot id: A0A6J3E727
names: Subcellular Location Annotation
messages: Membrane

219594:CCNL2
gene id: 219594:CCNL2
uniprot id: A0A6J3E0Q6
names: Similarity
messages: Belongs to the cyclin family.

219594:MIOX
gene id: 219594:MIOX
uniprot id: A0A6J3DQ32
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the myo-inositol oxygenase family.
messages: Binds 2 iron ions per subunit.
messages: Cytoplasm

219594:SPTB
gene id: 219594:SPTB
uniprot id: A0A6J3D3D4
names: Similarity
messages: Belongs to the spectrin family.

219594:GUK1
gene id: 219594:GUK1
uniprot id: A0A6J3CI71
uniprot id: A0A6J3CK34
names: Similarity
messages: Belongs to the guanylate kinase family.

219594:HPDL
gene id: 219594:HPDL
uniprot id: A0A6J3DAQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4HPPD family.
messages: Catalyzes the conversion of 4-hydroxyphenylpyruvic acid to homogentisic acid, one of the steps in tyrosine catabolism.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane

219594:HMGN1
gene id: 219594:HMGN1
uniprot id: A0A6J3D956
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HMGN family.
messages: Nucleus

219594:ADAMTS3
gene id: 219594:ADAMTS3
uniprot id: A0A6J3CU46
uniprot id: A0A6J3D095
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

219594:LDLRAD1
gene id: 219594:LDLRAD1
uniprot id: A0A6J3DDR9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:APMAP
gene id: 219594:APMAP
uniprot id: A0A6J3CND6
uniprot id: A0A6J3CQC1
names: Similarity
messages: Belongs to the strictosidine synthase family.

219594:MYO1G
gene id: 219594:MYO1G
uniprot id: A0A6J3CM97
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

219594:TRAF1
gene id: 219594:TRAF1
uniprot id: A0A6J3DZZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TNF receptor-associated factor family.
messages: Cytoplasm

219594:SH3GL3
gene id: 219594:SH3GL3
uniprot id: A0A6J3DP18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endophilin family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Membrane

219594:UBE2F
gene id: 219594:UBE2F
uniprot id: A0A6J3D5P4
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

219594:TCEA2
gene id: 219594:TCEA2
uniprot id: A0A6J3DS30
uniprot id: A0A6J3DX67
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFS-II family.
messages: Necessary for efficient RNA polymerase II transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by S-II allows the resumption of elongation from the new 3'-terminus.
messages: Nucleus

219594:ABCC9
gene id: 219594:ABCC9
uniprot id: A0A6J3EJJ2
uniprot id: A0A6J3EPW5
uniprot id: A0A6J3ERB3
names: Subunit
messages: Interacts with KCNJ11.

219594:OSBPL2
gene id: 219594:OSBPL2
uniprot id: A0A6J3DRH4
names: Similarity
messages: Belongs to the OSBP family.

219594:NPB
gene id: 219594:NPB
uniprot id: A0A6J3DWU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neuropeptide B/W family.
messages: Secreted

219594:ZNRF3
gene id: 219594:ZNRF3
uniprot id: A0A6J3DVP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZNRF3 family.
messages: Cell membrane
messages: Membrane

219594:HHEX
gene id: 219594:HHEX
uniprot id: A0A6J3D7K0
names: Subcellular Location Annotation
messages: Nucleus

219594:LOC116501416
gene id: 219594:LOC116501416
uniprot id: A0A6J3EI30
uniprot id: A0A6J3ELS8
names: Similarity
messages: Belongs to the YOS1 family.

219594:NDUFS3
gene id: 219594:NDUFS3
uniprot id: A0A6J3D4B4
names: Similarity
messages: Belongs to the complex I 30 kDa subunit family.

219594:GOSR1
gene id: 219594:GOSR1
uniprot id: A0A6J3E4N3
uniprot id: A0A6J3E5P3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GOSR1 family.
messages: Component of several multiprotein Golgi SNARE complexes.
messages: Golgi apparatus membrane
messages: Involved in transport from the ER to the Golgi apparatus as well as in intra-Golgi transport. It belongs to a super-family of proteins called t-SNAREs or soluble NSF (N-ethylmaleimide-sensitive factor) attachment protein receptor. May play a protective role against hydrogen peroxide induced cytotoxicity under glutathione depleted conditions in neuronal cells by regulating the intracellular ROS levels via inhibition of p38 MAPK (MAPK11, MAPK12, MAPK13 and MAPK14). Participates in docking and fusion stage of ER to cis-Golgi transport. Plays an important physiological role in VLDL-transport vesicle-Golgi fusion and thus in VLDL delivery to the hepatic cis-Golgi.
messages: Membrane

219594:ADM
gene id: 219594:ADM
uniprot id: A0A6J3D0A1
uniprot id: A0A6J3D2P0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adrenomedullin family.
messages: Secreted

219594:MND1
gene id: 219594:MND1
uniprot id: A0A6J3CV16
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MND1 family.
messages: Nucleus
messages: Required for proper homologous chromosome pairing and efficient cross-over and intragenic recombination during meiosis.

219594:NLGN1
gene id: 219594:NLGN1
uniprot id: A0A6J3DCM1
uniprot id: A0A6J3DGI7
uniprot id: A0A6J3DI60
uniprot id: A0A6J3DIQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type-B carboxylesterase/lipase family.
messages: Cell membrane
messages: Membrane

219594:DDR2
gene id: 219594:DDR2
uniprot id: A0A6J3D9Q2
uniprot id: A0A6J3DDC0
names: Subcellular Location Annotation
messages: Membrane

219594:ENAH
gene id: 219594:ENAH
uniprot id: A0A6J3CLF4
uniprot id: A0A6J3CLF9
uniprot id: A0A6J3CN27
uniprot id: A0A6J3CP34
uniprot id: A0A6J3CRB8
uniprot id: A0A6J3CSC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ena/VASP family.
messages: cytoskeleton

219594:HSPD1
gene id: 219594:HSPD1
uniprot id: A0A6J3D545
names: Similarity
messages: Belongs to the chaperonin (HSP60) family.

219594:GALT
gene id: 219594:GALT
uniprot id: A0A6J3EHL3
names: Cofactor
names: Similarity
messages: Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.
messages: Binds 1 Fe cation per subunit.

219594:CCDC181
gene id: 219594:CCDC181
uniprot id: A0A6J3CS11
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCDC181 family.
messages: Microtubule-binding protein that localizes to the microtubular manchette of elongating spermatids.
messages: cytoskeleton
messages: flagellum

219594:ADSS1
gene id: 219594:ADSS1
uniprot id: A0A6J3D169
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.
messages: Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis.

219594:PRPS2
gene id: 219594:PRPS2
uniprot id: A0A6J3E0Z5
uniprot id: A0A6J3E3N5
uniprot id: A0A6J3E4J4
uniprot id: A0A6J3E4K5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family.
messages: Catalyzes the synthesis of phosphoribosylpyrophosphate (PRPP) that is essential for nucleotide synthesis.
messages: Homodimer. The active form is probably a hexamer composed of 3 homodimers.

219594:RGS1
gene id: 219594:RGS1
uniprot id: A0A6J3DFW5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: cytosol

219594:DMC1
gene id: 219594:DMC1
uniprot id: A0A6J3EA36
names: Similarity
messages: Belongs to the RecA family. DMC1 subfamily.

219594:SCML2
gene id: 219594:SCML2
uniprot id: A0A6J3EI83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCM family.
messages: Nucleus

219594:ATP6V1C2
gene id: 219594:ATP6V1C2
uniprot id: A0A6J3CS43
names: Function
names: Similarity
names: Subunit
messages: Belongs to the V-ATPase C subunit family.
messages: Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex. The V1 complex consists of three catalytic AB heterodimers that form a heterohexamer, three peripheral stalks each consisting of EG heterodimers, one central rotor including subunits D and F, and the regulatory subunits C and H. The proton translocation complex V0 consists of the proton transport subunit a, a ring of proteolipid subunits c9c'', rotary subunit d, subunits e and f, and two accessory subunits.

219594:SLC24A2
gene id: 219594:SLC24A2
uniprot id: A0A6J3EHI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. SLC24A subfamily.
messages: Membrane

219594:TNFRSF4
gene id: 219594:TNFRSF4
uniprot id: A0A6J3E6C2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:DUS3L
gene id: 219594:DUS3L
uniprot id: A0A6J3E7V4
uniprot id: A0A6J3E9E3
uniprot id: A0A6J3ECI0
names: Similarity
messages: Belongs to the dus family. Dus3 subfamily.

219594:NCAPH2
gene id: 219594:NCAPH2
uniprot id: A0A6J3DQE2
uniprot id: A0A6J3DSQ4
names: Similarity
messages: Belongs to the CND2 H2 (condensin-2 subunit 2) family.

219594:FAAH2
gene id: 219594:FAAH2
uniprot id: A0A6J3DNB3
names: Similarity
messages: Belongs to the amidase family.

219594:CCR4
gene id: 219594:CCR4
uniprot id: A0A6J3CLG2
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

219594:NSUN2
gene id: 219594:NSUN2
uniprot id: A0A6J3CFZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: extracellular exosome

219594:CUL3
gene id: 219594:CUL3
uniprot id: A0A6J3DHZ3
names: Similarity
messages: Belongs to the cullin family.

219594:CA12
gene id: 219594:CA12
uniprot id: A0A6J3DLW2
names: Function
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

219594:PLXNB2
gene id: 219594:PLXNB2
uniprot id: A0A6J3DU32
names: Caution
names: Similarity
messages: Belongs to the plexin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:DOCK5
gene id: 219594:DOCK5
uniprot id: A0A6J3EFM7
names: Similarity
messages: Belongs to the DOCK family.

219594:NCK2
gene id: 219594:NCK2
uniprot id: A0A6J3EH10
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Endoplasmic reticulum

219594:EVC
gene id: 219594:EVC
uniprot id: A0A6J3CUX7
uniprot id: A0A6J3D120
names: Subcellular Location Annotation
messages: Membrane
messages: cilium basal body
messages: cilium membrane

219594:LOC116499887
gene id: 219594:LOC116499887
uniprot id: A0A6J3EFD4
names: Subcellular Location Annotation
messages: Membrane

219594:LOC116499978
gene id: 219594:LOC116499978
uniprot id: A0A6J3EFQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:BANP
gene id: 219594:BANP
uniprot id: A0A6J3DMI0
uniprot id: A0A6J3DP91
names: Similarity
messages: Belongs to the BANP/SMAR1 family.

219594:LOC116499987
gene id: 219594:LOC116499987
uniprot id: A0A6J3EFV2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:LOC116485365
gene id: 219594:LOC116485365
uniprot id: A0A6J3CC30
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:TET3
gene id: 219594:TET3
uniprot id: A0A6J3E857
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the TET family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Dioxygenase that catalyzes the conversion of the modified genomic base 5-methylcytosine (5mC) into 5-hydroxymethylcytosine (5hmC) and plays a key role in epigenetic chromatin reprogramming during embryonic development.
messages: The zinc ions have a structural role.

219594:PRKD3
gene id: 219594:PRKD3
uniprot id: A0A6J3CVF8
names: Activity Regulation
names: Similarity
names: Subcellular Location Annotation
messages: Activated by DAG and phorbol esters.
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PKD subfamily.
messages: Cytoplasm
messages: Membrane

219594:ITPK1
gene id: 219594:ITPK1
uniprot id: A0A6J3CZ15
names: Similarity
messages: Belongs to the ITPK1 family.

219594:CCDC43
gene id: 219594:CCDC43
uniprot id: A0A6J3E494
names: Similarity
messages: Belongs to the CCDC43 family.

219594:PCSK1
gene id: 219594:PCSK1
uniprot id: A0A6J3EHB1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S8 family.
messages: Involved in the processing of hormone and other protein precursors at sites comprised of pairs of basic amino acid residues. Substrates include POMC, renin, enkephalin, dynorphin, somatostatin, insulin and AGRP.
messages: Vesicle
messages: secretory vesicle

219594:TTC3
gene id: 219594:TTC3
uniprot id: A0A6J3CV33
uniprot id: A0A6J3CXU4
names: Subcellular Location Annotation
messages: Cytoplasm

219594:SLC25A1
gene id: 219594:SLC25A1
uniprot id: A0A6J3E061
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

219594:METTL2A
gene id: 219594:METTL2A
uniprot id: A0A6J3E9S4
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. METL family.
messages: S-adenosyl-L-methionine-dependent methyltransferase.

219594:NMUR2
gene id: 219594:NMUR2
uniprot id: A0A6J3DSX8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for the neuromedin-U and neuromedin-S neuropeptides.

219594:LAMTOR5
gene id: 219594:LAMTOR5
uniprot id: A0A6J3ECK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LAMTOR5 family.
messages: Lysosome

219594:CNDP2
gene id: 219594:CNDP2
uniprot id: A0A6J3CH38
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20A family.
messages: Binds 2 manganese ions per subunit.

219594:ODF2L
gene id: 219594:ODF2L
uniprot id: A0A6J3DDA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ODF2 family.
messages: centrosome

219594:PROM1
gene id: 219594:PROM1
uniprot id: A0A6J3CVY3
uniprot id: A0A6J3CY88
uniprot id: A0A6J3CYK1
uniprot id: A0A6J3CYK7
uniprot id: A0A6J3D0U3
uniprot id: A0A6J3D0U7
uniprot id: A0A6J3D1Z7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prominin family.
messages: Membrane
messages: microvillus membrane

219594:LOC116497750
gene id: 219594:LOC116497750
uniprot id: A0A6J3E1U9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the natriuretic peptide family.
messages: Secreted

219594:THBS4
gene id: 219594:THBS4
uniprot id: A0A6J3EKL4
names: Caution
names: Similarity
messages: Belongs to the thrombospondin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:HS6ST2
gene id: 219594:HS6ST2
uniprot id: A0A6J3DRB8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 6-O-sulfation enzyme which catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to position 6 of the N-sulfoglucosamine residue (GlcNS) of heparan sulfate.
messages: Belongs to the sulfotransferase 6 family.
messages: Membrane

219594:LAMP3
gene id: 219594:LAMP3
uniprot id: A0A6J3DGK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LAMP family.
messages: Endosome membrane

219594:LOC116501388
gene id: 219594:LOC116501388
uniprot id: A0A6J3ELQ7
names: Function
messages: The products of the Gag polyproteins of infectious retroviruses perform highly complex orchestrated tasks during the assembly, budding, maturation, and infection stages of the viral replication cycle. During viral assembly, the proteins form membrane associations and self-associations that ultimately result in budding of an immature virion from the infected cell. Gag precursors also function during viral assembly to selectively bind and package two plus strands of genomic RNA. Endogenous Gag proteins may have kept, lost or modified their original function during evolution.

219594:ANXA2
gene id: 219594:ANXA2
uniprot id: A0A6J3DMK7
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: A pair of annexin repeats may form one binding site for calcium and phospholipid.
messages: Belongs to the annexin family.
messages: Membrane
messages: basement membrane

219594:PTCH2
gene id: 219594:PTCH2
uniprot id: A0A6J3D9M5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the patched family.
messages: Membrane

219594:WNT8B
gene id: 219594:WNT8B
uniprot id: A0A6J3D9C0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

219594:ANXA11
gene id: 219594:ANXA11
uniprot id: A0A6J3DA39
names: Domain
names: Similarity
messages: A pair of annexin repeats may form one binding site for calcium and phospholipid.
messages: Belongs to the annexin family.

219594:NR2F6
gene id: 219594:NR2F6
uniprot id: A0A6J3EEP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

219594:RSPO1
gene id: 219594:RSPO1
uniprot id: A0A6J3E2Y7
names: Similarity
messages: Belongs to the R-spondin family.

219594:LOC116500888
gene id: 219594:LOC116500888
uniprot id: A0A6J3EFV5
names: Similarity
messages: Belongs to the avidin/streptavidin family.

219594:ESR1
gene id: 219594:ESR1
uniprot id: A0A6J3CPB2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nuclear hormone receptor family. NR3 subfamily.
messages: Binds DNA as a homodimer.
messages: Nucleus
messages: The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.

219594:PDK4
gene id: 219594:PDK4
uniprot id: A0A6J3CPQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PDK/BCKDK protein kinase family.
messages: Mitochondrion matrix

219594:LOC116489176
gene id: 219594:LOC116489176
uniprot id: A0A6J3CYA5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

219594:STAG1
gene id: 219594:STAG1
uniprot id: A0A6J3DCW8
uniprot id: A0A6J3DIF8
uniprot id: A0A6J3DJ08
uniprot id: A0A6J3DJ14
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SCC3 family.
messages: Chromosome
messages: Component of cohesin complex, a complex required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate.
messages: Nucleus
messages: Part of the cohesin complex which is composed of a heterodimer between a SMC1 protein (SMC1A or SMC1B) and SMC3, which are attached via their hinge domain, and RAD21 which link them at their heads, and one STAG protein.
messages: centromere

219594:MAFA
gene id: 219594:MAFA
uniprot id: A0A6J3CP75
names: Similarity
messages: Belongs to the bZIP family. Maf subfamily.

219594:CLDN1
gene id: 219594:CLDN1
uniprot id: A0A6J3DFZ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

219594:MAGI1
gene id: 219594:MAGI1
uniprot id: A0A6J3DDY8
uniprot id: A0A6J3DDZ3
uniprot id: A0A6J3DGR1
uniprot id: A0A6J3DGR6
uniprot id: A0A6J3DHY6
uniprot id: A0A6J3DHZ0
uniprot id: A0A6J3DHZ6
uniprot id: A0A6J3DJK9
uniprot id: A0A6J3DJL3
uniprot id: A0A6J3DK36
uniprot id: A0A6J3DK44
names: Subcellular Location Annotation
messages: Membrane

219594:CDK17
gene id: 219594:CDK17
uniprot id: A0A6J3CQ39
names: Similarity
messages: Belongs to the protein kinase superfamily.

219594:GALNT8
gene id: 219594:GALNT8
uniprot id: A0A6J3CVY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

219594:LOC116498576
gene id: 219594:LOC116498576
uniprot id: A0A6J3E573
names: Similarity
names: Subunit
messages: Belongs to the avian keratin family.
messages: The avian keratins (F-ker, S-ker, C-ker and B-ker) are a complex mixture of very similar polypeptides.

219594:UBE2C
gene id: 219594:UBE2C
uniprot id: A0A6J3DWG2
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

219594:LOC116498619
gene id: 219594:LOC116498619
uniprot id: A0A6J3EAF8
uniprot id: A0A6J3EBZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transcription factor STAT family.
messages: Cytoplasm
messages: Nucleus

219594:CBLB
gene id: 219594:CBLB
uniprot id: A0A6J3EFY6
names: Domain
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: E3 ubiquitin-protein ligase which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, and transfers it to substrates, generally promoting their degradation by the proteasome.
messages: The N-terminus is composed of the phosphotyrosine binding (PTB) domain, a short linker region and the RING-type zinc finger. The PTB domain, which is also called TKB (tyrosine kinase binding) domain, is composed of three different subdomains: a four-helix bundle (4H), a calcium-binding EF hand and a divergent SH2 domain.

219594:LOC116501065
gene id: 219594:LOC116501065
uniprot id: A0A6J3EGI2
names: Similarity
messages: Belongs to the G-alpha family. G(q) subfamily.

219594:FAM110D
gene id: 219594:FAM110D
uniprot id: A0A6J3E550
names: Similarity
messages: Belongs to the FAM110 family.

219594:TEKT2
gene id: 219594:TEKT2
uniprot id: A0A6J3EA47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tektin family.
messages: flagellum

219594:LOC116501012
gene id: 219594:LOC116501012
uniprot id: A0A6J3ELL0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G protein gamma family.
messages: Cell membrane
messages: G proteins are composed of 3 units; alpha, beta and gamma.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

219594:ARPC5
gene id: 219594:ARPC5
uniprot id: A0A6J3DG96
names: Function
names: Similarity
messages: Belongs to the ARPC5 family.
messages: Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development.

219594:LXN
gene id: 219594:LXN
uniprot id: A0A6J3DIL8
names: Similarity
messages: Belongs to the protease inhibitor I47 (latexin) family.

219594:GDF2
gene id: 219594:GDF2
uniprot id: A0A6J3D8B6
names: Similarity
messages: Belongs to the TGF-beta family.

219594:HOOK1
gene id: 219594:HOOK1
uniprot id: A0A6J3DAA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the hook family.
messages: cytoskeleton

219594:LOC116498334
gene id: 219594:LOC116498334
uniprot id: A0A6J3E995
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the somatotropin/prolactin family.
messages: Secreted

219594:RAB5IF
gene id: 219594:RAB5IF
uniprot id: A0A6J3DXQ5
names: Subcellular Location Annotation
messages: Membrane

219594:LOC116498264
gene id: 219594:LOC116498264
uniprot id: A0A6J3E433
names: Cofactor
names: PTM
names: Similarity
messages: Belongs to the copper/topaquinone oxidase family.
messages: Contains 1 topaquinone per subunit.
messages: Topaquinone (TPQ) is generated by copper-dependent autoxidation of a specific tyrosyl residue.

219594:GDF1
gene id: 219594:GDF1
uniprot id: A0A6J3E733
names: Similarity
messages: Belongs to the TGF-beta family.

219594:GSPT1
gene id: 219594:GSPT1
uniprot id: A0A6J3DPN4
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.

219594:CCL20
gene id: 219594:CCL20
uniprot id: A0A6J3DDS1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine beta (chemokine CC) family.
messages: Secreted

219594:SLC9A8
gene id: 219594:SLC9A8
uniprot id: A0A6J3DTR2
uniprot id: A0A6J3DXQ7
names: Similarity
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.

219594:LOC116497173
gene id: 219594:LOC116497173
uniprot id: A0A6J3E492
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transient receptor (TC 1.A.4) family. TrpV subfamily. TRPV1 sub-subfamily.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane
messages: dendritic spine membrane

219594:TNS3
gene id: 219594:TNS3
uniprot id: A0A6J3CGH7
uniprot id: A0A6J3CI25
uniprot id: A0A6J3CJ45
names: Similarity
messages: Belongs to the PTEN phosphatase protein family.

219594:LOC116492398
gene id: 219594:LOC116492398
uniprot id: A0A6J3DBZ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ubiquitin family. SUMO subfamily.
messages: Nucleus

219594:TNFAIP6
gene id: 219594:TNFAIP6
uniprot id: A0A6J3D7H8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:MCUR1
gene id: 219594:MCUR1
uniprot id: A0A6J3CNR4
names: Similarity
messages: Belongs to the CCDC90 family.

219594:SELENOT
gene id: 219594:SELENOT
uniprot id: A0A6J3DFQ5
names: Similarity
messages: Belongs to the SelWTH family. Selenoprotein T subfamily.

219594:GTF2E1
gene id: 219594:GTF2E1
uniprot id: A0A6J3EPN0
names: Function
names: Similarity
messages: Belongs to the TFIIE alpha subunit family.
messages: Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase.

219594:GNL2
gene id: 219594:GNL2
uniprot id: A0A6J3E8N7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. NOG2 subfamily.
messages: GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation.
messages: nucleolus

219594:GPR3
gene id: 219594:GPR3
uniprot id: A0A6J3E8B8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:DHRS11
gene id: 219594:DHRS11
uniprot id: A0A6J3E5F4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

219594:LOC116493186
gene id: 219594:LOC116493186
uniprot id: A0A6J3DJH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.
messages: Membrane

219594:AZIN2
gene id: 219594:AZIN2
uniprot id: A0A6J3EAC0
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

219594:TMEM120B
gene id: 219594:TMEM120B
uniprot id: A0A6J3DXY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM120 family.
messages: Membrane
messages: Nucleus inner membrane

219594:MDM2
gene id: 219594:MDM2
uniprot id: A0A6J3CLL7
uniprot id: A0A6J3CPZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MDM2/MDM4 family.
messages: Cytoplasm
messages: nucleolus
messages: nucleoplasm

219594:KPNB1
gene id: 219594:KPNB1
uniprot id: A0A6J3E9I8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the importin beta family. Importin beta-1 subfamily.
messages: Cytoplasm

219594:TOM1L2
gene id: 219594:TOM1L2
uniprot id: A0A6J3DR60
uniprot id: A0A6J3DTD8
uniprot id: A0A6J3DVI3
names: Similarity
messages: Belongs to the TOM1 family.

219594:LOC116499725
gene id: 219594:LOC116499725
uniprot id: A0A6J3E9S3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the selenium-binding protein family.
messages: Catalyzes the oxidation of methanethiol, an organosulfur compound known to be produced in substantial amounts by gut bacteria. Selenium-binding protein which may be involved in the sensing of reactive xenobiotics in the cytoplasm. May be involved in intra-Golgi protein transport.
messages: Membrane
messages: Nucleus
messages: cytosol

219594:MTHFR
gene id: 219594:MTHFR
uniprot id: A0A6J3E7Z7
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

219594:NKX6-2
gene id: 219594:NKX6-2
uniprot id: A0A6J3DCK7
names: Subcellular Location Annotation
messages: Nucleus

219594:PDE4B
gene id: 219594:PDE4B
uniprot id: A0A6J3D9Y5
uniprot id: A0A6J3DCK9
uniprot id: A0A6J3DDK6
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family. PDE4 subfamily.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

219594:LOC116500139
gene id: 219594:LOC116500139
uniprot id: A0A6J3ECJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:PPP1R1C
gene id: 219594:PPP1R1C
uniprot id: A0A6J3D706
names: Similarity
messages: Belongs to the protein phosphatase inhibitor 1 family.

219594:LOC116498349
gene id: 219594:LOC116498349
uniprot id: A0A6J3EAQ7
names: Similarity
names: Subunit
messages: Belongs to the avian keratin family.
messages: The avian keratins (F-ker, S-ker, C-ker and B-ker) are a complex mixture of very similar polypeptides.

219594:KCNE2
gene id: 219594:KCNE2
uniprot id: A0A6J3CT59
names: Similarity
messages: Belongs to the potassium channel KCNE family.

219594:SPAG9
gene id: 219594:SPAG9
uniprot id: A0A6J3DW81
uniprot id: A0A6J3DY24
uniprot id: A0A6J3E0E9
uniprot id: A0A6J3E174
uniprot id: A0A6J3E180
uniprot id: A0A6J3E2C0
uniprot id: A0A6J3E2C4
names: Similarity
messages: Belongs to the JIP scaffold family.

219594:TM2D3
gene id: 219594:TM2D3
uniprot id: A0A6J3DKT6
uniprot id: A0A6J3DMD5
names: Subcellular Location Annotation
messages: Membrane

219594:PFKM
gene id: 219594:PFKM
uniprot id: A0A6J3EAV4
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP, AMP, or fructose 2,6-bisphosphate, and allosterically inhibited by ATP or citrate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade "E" sub-subfamily.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homo- and heterotetramers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:MYO6
gene id: 219594:MYO6
uniprot id: A0A6J3CM35
uniprot id: A0A6J3CM39
uniprot id: A0A6J3CNU6
uniprot id: A0A6J3CNV1
uniprot id: A0A6J3CPR2
uniprot id: A0A6J3CS07
uniprot id: A0A6J3CT44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
messages: clathrin-coated pit
messages: clathrin-coated vesicle
messages: filopodium
messages: microvillus

219594:USB1
gene id: 219594:USB1
uniprot id: A0A6J3DK42
uniprot id: A0A6J3DQK9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 2H phosphoesterase superfamily. USB1 family.
messages: Nucleus
messages: Phosphodiesterase responsible for the U6 snRNA 3' end processing. Acts as an exoribonuclease (RNase) responsible for trimming the poly(U) tract of the last nucleotides in the pre-U6 snRNA molecule, leading to the formation of mature U6 snRNA.

219594:SLC5A1
gene id: 219594:SLC5A1
uniprot id: A0A6J3DY43
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

219594:DCSTAMP
gene id: 219594:DCSTAMP
uniprot id: A0A6J3CI03
names: Subcellular Location Annotation
messages: Membrane

219594:GLP2R
gene id: 219594:GLP2R
uniprot id: A0A6J3DY94
names: Subcellular Location Annotation
messages: Membrane

219594:TIMM17A
gene id: 219594:TIMM17A
uniprot id: A0A6J3E6H6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Tim17/Tim22/Tim23 family.
messages: Component of the TIM23 complex, at least composed of TIM23, TIM17, TIM50 and TIM21.
messages: Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.
messages: Membrane
messages: Mitochondrion inner membrane

219594:RP2
gene id: 219594:RP2
uniprot id: A0A6J3EP36
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a GTPase-activating protein (GAP) for tubulin in concert with tubulin-specific chaperone C, but does not enhance tubulin heterodimerization.
messages: Belongs to the TBCC family.
messages: Cell membrane
messages: Membrane

219594:KIF24
gene id: 219594:KIF24
uniprot id: A0A6J3EGY0
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

219594:SLC4A7
gene id: 219594:SLC4A7
uniprot id: A0A6J3CLK7
uniprot id: A0A6J3CMR7
uniprot id: A0A6J3CPW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anion exchanger (TC 2.A.31) family.
messages: Membrane

219594:IMPG2
gene id: 219594:IMPG2
uniprot id: A0A6J3EJI4
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: interphotoreceptor matrix

219594:FUCA2
gene id: 219594:FUCA2
uniprot id: A0A6J3CKN1
uniprot id: A0A6J3CRM0
names: Function
names: Similarity
names: Subunit
messages: Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins.
messages: Belongs to the glycosyl hydrolase 29 family.
messages: Homotetramer.

219594:DPYSL3
gene id: 219594:DPYSL3
uniprot id: A0A6J3DPM2
uniprot id: A0A6J3DTJ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.
messages: Cytoplasm
messages: Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, neuronal growth cone collapse and cell migration.
messages: growth cone

219594:SFXN2
gene id: 219594:SFXN2
uniprot id: A0A6J3DAR8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sideroflexin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Mitochondrion membrane

219594:LOC116501389
gene id: 219594:LOC116501389
uniprot id: A0A6J3ELN1
names: Similarity
messages: Belongs to the G-alpha family. G(q) subfamily.

219594:ACAD8
gene id: 219594:ACAD8
uniprot id: A0A6J3E8N9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

219594:LOC116501963
gene id: 219594:LOC116501963
uniprot id: A0A6J3ENQ2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

219594:MRPL16
gene id: 219594:MRPL16
uniprot id: A0A6J3D2G0
names: Similarity
messages: Belongs to the universal ribosomal protein uL16 family.

219594:CDH5
gene id: 219594:CDH5
uniprot id: A0A6J3DLR9
uniprot id: A0A6J3DQD1
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell junction
messages: Cell membrane
messages: Membrane

219594:VPS13B
gene id: 219594:VPS13B
uniprot id: A0A6J3CJT5
names: Similarity
messages: Belongs to the VPS13 family.

219594:LOC116499634
gene id: 219594:LOC116499634
uniprot id: A0A6J3E9D8
uniprot id: A0A6J3EG64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 30 family.
messages: Lysosome membrane

219594:CHMP4C
gene id: 219594:CHMP4C
uniprot id: A0A6J3CIF2
names: Similarity
messages: Belongs to the SNF7 family.

219594:LOC116487105
gene id: 219594:LOC116487105
uniprot id: A0A6J3CMC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cullin family.
messages: Cytoplasm

219594:FLOT2
gene id: 219594:FLOT2
uniprot id: A0A6J3DZK1
uniprot id: A0A6J3E142
uniprot id: A0A6J3E4P0
uniprot id: A0A6J3E5Q0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the band 7/mec-2 family. Flotillin subfamily.
messages: Endosome
messages: Heterooligomeric complex.
messages: Membrane

219594:ACLY
gene id: 219594:ACLY
uniprot id: A0A6J3E4C5
uniprot id: A0A6J3E8P4
names: Function
names: Similarity
names: Subunit
messages: Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the succinate/malate CoA ligase alpha subunit family.
messages: In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family.

219594:YARS1
gene id: 219594:YARS1
uniprot id: A0A6J3EAB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Nucleus

219594:FUT10
gene id: 219594:FUT10
uniprot id: A0A6J3EFG9
uniprot id: A0A6J3EGX0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 10 family.
messages: Golgi stack membrane
messages: Probable fucosyltransferase.

219594:LOC116500083
gene id: 219594:LOC116500083
uniprot id: A0A6J3EG34
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3 GTPase family.

219594:LOC116496606
gene id: 219594:LOC116496606
uniprot id: A0A6J3DWF4
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

219594:LOC116500318
gene id: 219594:LOC116500318
uniprot id: A0A6J3EID1
names: Subcellular Location Annotation
messages: Membrane

219594:TAMM41
gene id: 219594:TAMM41
uniprot id: A0A6J3DIY7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAM41 family.
messages: Catalyzes the conversion of phosphatidic acid (PA) to CDP-diacylglycerol (CDP-DAG), an essential intermediate in the synthesis of phosphatidylglycerol, cardiolipin and phosphatidylinositol.
messages: Mitochondrion inner membrane

219594:PTCH1
gene id: 219594:PTCH1
uniprot id: A0A6J3EDE8
uniprot id: A0A6J3EI92
uniprot id: A0A6J3EIK2
uniprot id: A0A6J3EK88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the patched family.
messages: Membrane

219594:DHX29
gene id: 219594:DHX29
uniprot id: A0A6J3EFG3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-binding RNA helicase involved in translation initiation. Part of the 43S pre-initiation complex that is required for efficient initiation on mRNAs of higher eukaryotes with structured 5'-UTRs by promoting efficient NTPase-dependent 48S complex formation. Specifically binds to the 40S ribosome near the mRNA entrance. Does not possess a processive helicase activity.
messages: Belongs to the DEAD box helicase family. DEAH subfamily.
messages: Cytoplasm
messages: Part of the 43S pre-initiation complex (PIC).

219594:TIMM22
gene id: 219594:TIMM22
uniprot id: A0A6J3E0T8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Tim17/Tim22/Tim23 family.
messages: Component of the TIM22 complex.
messages: Essential core component of the TIM22 complex, a complex that mediates the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. In the TIM22 complex, it constitutes the voltage-activated and signal-gated channel. Forms a twin-pore translocase that uses the membrane potential as external driving force in 2 voltage-dependent steps.
messages: Membrane
messages: Mitochondrion inner membrane

219594:DBX1
gene id: 219594:DBX1
uniprot id: A0A6J3CWU8
names: Subcellular Location Annotation
messages: Nucleus

219594:PREP
gene id: 219594:PREP
uniprot id: A0A6J3CT99
names: Similarity
messages: Belongs to the peptidase S9A family.

219594:POU2F3
gene id: 219594:POU2F3
uniprot id: A0A6J3E7K1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POU transcription factor family. Class-2 subfamily.
messages: Nucleus

219594:RAP2B
gene id: 219594:RAP2B
uniprot id: A0A6J3DGJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Ras family.
messages: Endosome membrane
messages: Recycling endosome membrane

219594:SNX14
gene id: 219594:SNX14
uniprot id: A0A6J3CRA2
uniprot id: A0A6J3CSB1
names: Similarity
messages: Belongs to the sorting nexin family.

219594:KAT6B
gene id: 219594:KAT6B
uniprot id: A0A6J3D712
uniprot id: A0A6J3D9Q6
uniprot id: A0A6J3DCK0
names: Similarity
messages: Belongs to the MYST (SAS/MOZ) family.

219594:KPNA1
gene id: 219594:KPNA1
uniprot id: A0A6J3DK49
names: Similarity
messages: Belongs to the importin alpha family.

219594:MMP24
gene id: 219594:MMP24
uniprot id: A0A6J3DR91
names: Similarity
messages: Belongs to the peptidase M10A family.

219594:IL12B
gene id: 219594:IL12B
uniprot id: A0A6J3DSR3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IL-12B family.
messages: Heterodimer with IL12A; disulfide-linked. The heterodimer is known as interleukin IL-12.
messages: Secreted

219594:RPS21
gene id: 219594:RPS21
uniprot id: A0A6J3DU22
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS21 family.
messages: Component of the 40S small ribosomal subunit.
messages: Endoplasmic reticulum
messages: Rough endoplasmic reticulum
messages: cytosol

219594:OTULIN
gene id: 219594:OTULIN
uniprot id: A0A6J3CID6
uniprot id: A0A6J3CM00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C65 family. Otulin subfamily.
messages: Cytoplasm

219594:RPS27L
gene id: 219594:RPS27L
uniprot id: A0A6J3DKB4
names: Cofactor
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS27 family.
messages: Binds 1 zinc ion per subunit.

219594:LOC116491460
gene id: 219594:LOC116491460
uniprot id: A0A6J3DDA8
names: Similarity
messages: Belongs to the cytochrome P450 family.

219594:MAPKAP1
gene id: 219594:MAPKAP1
uniprot id: A0A6J3E201
uniprot id: A0A6J3E353
names: Similarity
messages: Belongs to the SIN1 family.

219594:MAGI2
gene id: 219594:MAGI2
uniprot id: A0A6J3CHD0
uniprot id: A0A6J3CHG1
uniprot id: A0A6J3CLW2
names: Subcellular Location Annotation
messages: Membrane

219594:LOC116487003
gene id: 219594:LOC116487003
uniprot id: A0A6J3CR58
names: Similarity
messages: Belongs to the cytochrome c oxidase VIIa family.

219594:RIC8B
gene id: 219594:RIC8B
uniprot id: A0A6J3EEW3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the synembryn family.
messages: Cytoplasm
messages: Guanine nucleotide exchange factor (GEF), which can activate some, but not all, G-alpha proteins by exchanging bound GDP for free GTP.
messages: Interacts with some GDP-bound G alpha proteins. Does not interact with G-alpha proteins when they are in complex with subunits beta and gamma.

219594:LOC116486360
gene id: 219594:LOC116486360
uniprot id: A0A6J3CHF6
uniprot id: A0A6J3CIZ3
names: Similarity
messages: Belongs to the AAA ATPase family.

219594:PCBP3
gene id: 219594:PCBP3
uniprot id: A0A6J3D2I8
uniprot id: A0A6J3D2J3
uniprot id: A0A6J3D2K2
uniprot id: A0A6J3D2K6
uniprot id: A0A6J3D2L1
uniprot id: A0A6J3D501
uniprot id: A0A6J3D506
uniprot id: A0A6J3D516
uniprot id: A0A6J3D521
uniprot id: A0A6J3D5C8
uniprot id: A0A6J3D5E4
uniprot id: A0A6J3D5E8
uniprot id: A0A6J3D7K4
uniprot id: A0A6J3D7K8
uniprot id: A0A6J3D7L2
uniprot id: A0A6J3D7L7
uniprot id: A0A6J3D7M2
uniprot id: A0A6J3D8F0
uniprot id: A0A6J3D8F5
uniprot id: A0A6J3D8G3
uniprot id: A0A6J3D8H2
names: Subcellular Location Annotation
messages: Cytoplasm

219594:GABRA3
gene id: 219594:GABRA3
uniprot id: A0A6J3DLF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

219594:DGKA
gene id: 219594:DGKA
uniprot id: A0A6J3EBT3
names: Similarity
messages: Belongs to the eukaryotic diacylglycerol kinase family.

219594:ERH
gene id: 219594:ERH
uniprot id: A0A6J3D1L4
names: Function
names: Similarity
messages: Belongs to the E(R) family.
messages: May have a role in the cell cycle.

219594:DIAPH3
gene id: 219594:DIAPH3
uniprot id: A0A6J3ERX8
names: Similarity
messages: Belongs to the formin homology family. Diaphanous subfamily.

219594:TSR1
gene id: 219594:TSR1
uniprot id: A0A6J3E617
names: Subcellular Location Annotation
messages: nucleolus

219594:RPL36
gene id: 219594:RPL36
uniprot id: A0A6J3EBV1
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL36 family.

219594:LOC116488132
gene id: 219594:LOC116488132
uniprot id: A0A6J3CTD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. Very large inducible GTPase (VLIG) family.
messages: Nucleus

219594:THRAP3
gene id: 219594:THRAP3
uniprot id: A0A6J3E398
uniprot id: A0A6J3E886
names: Similarity
messages: Belongs to the BCLAF1/THRAP3 family.

219594:ANKH
gene id: 219594:ANKH
uniprot id: A0A6J3CQ44
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ANKH family.
messages: Membrane
messages: Regulates intra- and extracellular levels of inorganic pyrophosphate (PPi), probably functioning as PPi transporter.

219594:SYK
gene id: 219594:SYK
uniprot id: A0A6J3EIL4
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. SYK/ZAP-70 subfamily.

219594:LIN28B
gene id: 219594:LIN28B
uniprot id: A0A6J3CRA3
uniprot id: A0A6J3CRY3
uniprot id: A0A6J3CUA0
uniprot id: A0A6J3CVD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lin-28 family.
messages: nucleolus

219594:VIPAS39
gene id: 219594:VIPAS39
uniprot id: A0A6J3D0V5
names: Subcellular Location Annotation
messages: Endosome
messages: Late endosome
messages: Vesicle

219594:TMEM189
gene id: 219594:TMEM189
uniprot id: A0A6J3DXB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acid desaturase CarF family.
messages: Membrane

219594:PSMD12
gene id: 219594:PSMD12
uniprot id: A0A6J3E129
names: Similarity
messages: Belongs to the proteasome subunit p55 family.

219594:LMOD2
gene id: 219594:LMOD2
uniprot id: A0A6J3EJP6
names: Subcellular Location Annotation
messages: cytoskeleton
messages: sarcomere

219594:RC3H2
gene id: 219594:RC3H2
uniprot id: A0A6J3DX34
uniprot id: A0A6J3E227
names: Subcellular Location Annotation
messages: P-body

219594:FIGN
gene id: 219594:FIGN
uniprot id: A0A6J3D6G2
uniprot id: A0A6J3D9S4
names: Similarity
messages: Belongs to the AAA ATPase family.

219594:LOC116501339
gene id: 219594:LOC116501339
uniprot id: A0A6J3EG88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:UIMC1
gene id: 219594:UIMC1
uniprot id: A0A6J3DNS4
uniprot id: A0A6J3DR34
uniprot id: A0A6J3DU04
uniprot id: A0A6J3DUU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RAP80 family.
messages: Nucleus

219594:ARHGEF28
gene id: 219594:ARHGEF28
uniprot id: A0A6J3ECI8
uniprot id: A0A6J3ECJ4
uniprot id: A0A6J3EDW7
uniprot id: A0A6J3EHD8
uniprot id: A0A6J3EHE2
uniprot id: A0A6J3EHM1
names: Subcellular Location Annotation
messages: Cytoplasm

219594:WNT7A
gene id: 219594:WNT7A
uniprot id: A0A6J3DH21
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

219594:ARHGEF6
gene id: 219594:ARHGEF6
uniprot id: A0A6J3DN53
uniprot id: A0A6J3DPY0
uniprot id: A0A6J3DRY9
names: Subcellular Location Annotation
messages: lamellipodium

219594:GPR161
gene id: 219594:GPR161
uniprot id: A0A6J3EJ96
uniprot id: A0A6J3EN41
uniprot id: A0A6J3EPH9
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

219594:MED8
gene id: 219594:MED8
uniprot id: A0A6J3DGR5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 8 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. May play a role as a target recruitment subunit in E3 ubiquitin-protein ligase complexes and thus in ubiquitination and subsequent proteasomal degradation of target proteins.
messages: Component of the Mediator complex.
messages: Nucleus

219594:CALHM5
gene id: 219594:CALHM5
uniprot id: A0A6J3CME7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CALHM family.
messages: Membrane

219594:HOXB6
gene id: 219594:HOXB6
uniprot id: A0A6J3E959
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus

219594:SSH1
gene id: 219594:SSH1
uniprot id: A0A6J3DV75
uniprot id: A0A6J3DXF2
uniprot id: A0A6J3DZB3
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family.

219594:CAPN6
gene id: 219594:CAPN6
uniprot id: A0A6J3DKZ7
names: Similarity
messages: Belongs to the peptidase C2 family.

219594:LOC116502362
gene id: 219594:LOC116502362
uniprot id: A0A6J3EK30
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

219594:LOC116495205
gene id: 219594:LOC116495205
uniprot id: A0A6J3DTY3
names: Caution
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:BLOC1S2
gene id: 219594:BLOC1S2
uniprot id: A0A6J3DDL3
names: Similarity
messages: Belongs to the BLOC1S2 family.

219594:TAFA4
gene id: 219594:TAFA4
uniprot id: A0A6J3DJ94
names: Similarity
messages: Belongs to the TAFA family.

219594:PNO1
gene id: 219594:PNO1
uniprot id: A0A6J3CTG0
names: Similarity
messages: Belongs to the PNO1 family.

219594:RGS14
gene id: 219594:RGS14
uniprot id: A0A6J3DSV0
names: Subcellular Location Annotation
messages: dendrite

219594:LIN54
gene id: 219594:LIN54
uniprot id: A0A6J3CUM7
uniprot id: A0A6J3CWY2
uniprot id: A0A6J3CZN9
uniprot id: A0A6J3D0S1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lin-54 family.
messages: Nucleus

219594:ANKRD13C
gene id: 219594:ANKRD13C
uniprot id: A0A6J3DF00
names: Subcellular Location Annotation
messages: Membrane

219594:SEZ6
gene id: 219594:SEZ6
uniprot id: A0A6J3E0C8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:TOMM20
gene id: 219594:TOMM20
uniprot id: A0A6J3CNS1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tom20 family.
messages: Membrane
messages: Mitochondrion outer membrane

219594:EDEM3
gene id: 219594:EDEM3
uniprot id: A0A6J3D8Z8
uniprot id: A0A6J3DCM0
uniprot id: A0A6J3DEX0
names: Similarity
messages: Belongs to the glycosyl hydrolase 47 family.

219594:UNC119
gene id: 219594:UNC119
uniprot id: A0A6J3E0H9
uniprot id: A0A6J3E5H9
names: Similarity
messages: Belongs to the PDE6D/unc-119 family.

219594:KCNH2
gene id: 219594:KCNH2
uniprot id: A0A6J3CI33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the potassium channel family. H (Eag) (TC 1.A.1.20) subfamily. Kv11.1/KCNH2 sub-subfamily.
messages: Membrane

219594:SLC25A28
gene id: 219594:SLC25A28
uniprot id: A0A6J3DBT7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

219594:CHAC2
gene id: 219594:CHAC2
uniprot id: A0A6J3CS82
names: Function
names: Similarity
messages: Belongs to the gamma-glutamylcyclotransferase family. ChaC subfamily.
messages: Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides.

219594:IAH1
gene id: 219594:IAH1
uniprot id: A0A6J3CTW5
names: Function
names: Similarity
messages: Belongs to the 'GDSL' lipolytic enzyme family. IAH1 subfamily.
messages: Probable lipase.

219594:ARL8A
gene id: 219594:ARL8A
uniprot id: A0A6J3EAY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane

219594:MBTPS1
gene id: 219594:MBTPS1
uniprot id: A0A6J3DJ21
names: Similarity
messages: Belongs to the peptidase S8 family.

219594:HPSE2
gene id: 219594:HPSE2
uniprot id: A0A6J3D9F2
names: Similarity
messages: Belongs to the glycosyl hydrolase 79 family.

219594:ATP10B
gene id: 219594:ATP10B
uniprot id: A0A6J3DT03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

219594:PAX5
gene id: 219594:PAX5
uniprot id: A0A6J3EE15
uniprot id: A0A6J3EJ90
uniprot id: A0A6J3EJ95
uniprot id: A0A6J3EKT7
uniprot id: A0A6J3EKU1
names: Subcellular Location Annotation
messages: Nucleus

219594:ADAMTS19
gene id: 219594:ADAMTS19
uniprot id: A0A6J3EEL2
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

219594:MTMR10
gene id: 219594:MTMR10
uniprot id: A0A6J3DNK6
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.

219594:GJD4
gene id: 219594:GJD4
uniprot id: A0A6J3CE36
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

219594:CAPZA1
gene id: 219594:CAPZA1
uniprot id: A0A6J3EAF2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the F-actin-capping protein alpha subunit family.
messages: F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.
messages: Heterodimer of an alpha and a beta subunit.

219594:CERT1
gene id: 219594:CERT1
uniprot id: A0A6J3EDL7
uniprot id: A0A6J3EH33
names: Subcellular Location Annotation
messages: Endoplasmic reticulum
messages: Golgi apparatus

219594:S100A11
gene id: 219594:S100A11
uniprot id: A0A6J3EB14
names: Similarity
names: Subunit
messages: Belongs to the S-100 family.
messages: Homodimer; disulfide-linked.

219594:PARP6
gene id: 219594:PARP6
uniprot id: A0A6J3DI61
uniprot id: A0A6J3DNN6
uniprot id: A0A6J3DPA7
names: Similarity
messages: Belongs to the ARTD/PARP family.

219594:LOC116495991
gene id: 219594:LOC116495991
uniprot id: A0A6J3DTF5
names: Similarity
messages: Belongs to the activator 1 small subunits family.

219594:FSTL3
gene id: 219594:FSTL3
uniprot id: A0A6J3EE79
names: Subcellular Location Annotation
messages: Secreted

219594:FBN3
gene id: 219594:FBN3
uniprot id: A0A6J3E8S8
uniprot id: A0A6J3EE02
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fibrillin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

219594:MGST1
gene id: 219594:MGST1
uniprot id: A0A6J3ENA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAPEG family.
messages: Membrane

219594:SLC7A6
gene id: 219594:SLC7A6
uniprot id: A0A6J3DQA6
names: Subcellular Location Annotation
messages: Membrane

219594:LOC116492601
gene id: 219594:LOC116492601
uniprot id: A0A6J3DCV3
names: Similarity
messages: Belongs to the cytochrome P450 family.

219594:PPIE
gene id: 219594:PPIE
uniprot id: A0A6J3E338
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family. PPIase E subfamily.
messages: Catalyzes the cis-trans isomerization of proline imidic peptide bonds in proteins.

219594:LOC116500177
gene id: 219594:LOC116500177
uniprot id: A0A6J3ECN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. BTN/MOG family.
messages: Membrane

219594:LOC116488189
gene id: 219594:LOC116488189
uniprot id: A0A6J3CR11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM47 family.
messages: Membrane

219594:XPA
gene id: 219594:XPA
uniprot id: A0A6J3EJU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XPA family.
messages: Nucleus

219594:FGF2
gene id: 219594:FGF2
uniprot id: A0A6J3CX03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heparin-binding growth factors family.
messages: Nucleus
messages: Secreted

219594:LOC116486734
gene id: 219594:LOC116486734
uniprot id: A0A6J3CNX6
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

219594:LOC116487511
gene id: 219594:LOC116487511
uniprot id: A0A6J3CSX4
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

219594:SEMA3C
gene id: 219594:SEMA3C
uniprot id: A0A6J3E4W2
uniprot id: A0A6J3E8G5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

219594:UBALD2
gene id: 219594:UBALD2
uniprot id: A0A6J3E169
names: Similarity
messages: Belongs to the UBALD family.

219594:MICAL1
gene id: 219594:MICAL1
uniprot id: A0A6J3E5T7
uniprot id: A0A6J3ECG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mical family.
messages: Cytoplasm

219594:TSPAN12
gene id: 219594:TSPAN12
uniprot id: A0A6J3D2Q2
uniprot id: A0A6J3D8K0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

219594:LOC116501060
gene id: 219594:LOC116501060
uniprot id: A0A6J3EF11
names: Similarity
messages: Belongs to the avidin/streptavidin family.

219594:SMARCD1
gene id: 219594:SMARCD1
uniprot id: A0A6J3EAP3
uniprot id: A0A6J3EFR8
names: Similarity
messages: Belongs to the SMARCD family.

219594:SMAD1
gene id: 219594:SMAD1
uniprot id: A0A6J3CXK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dwarfin/SMAD family.
messages: Cytoplasm
messages: Nucleus

219594:VTA1
gene id: 219594:VTA1
uniprot id: A0A6J3CT78
uniprot id: A0A6J3CUB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VTA1 family.
messages: Cytoplasm
messages: Endosome membrane
messages: Membrane

219594:C3H6orf58
gene id: 219594:C3H6orf58
uniprot id: A0A6J3CTX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LEG1 family.
messages: Secreted

219594:LOC116497136
gene id: 219594:LOC116497136
uniprot id: A0A6J3E0I6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

219594:LOC116493924
gene id: 219594:LOC116493924
uniprot id: A0A6J3DQ98
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

219594:SULF1
gene id: 219594:SULF1
uniprot id: A0A6J3CF76
uniprot id: A0A6J3CH31
uniprot id: A0A6J3CIU7
names: Cofactor
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfatase family.
messages: Binds 1 Ca(2+) ion per subunit.
messages: Cell surface
messages: Endoplasmic reticulum
messages: Golgi stack
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

219594:MAST3
gene id: 219594:MAST3
uniprot id: A0A6J3E7P1
uniprot id: A0A6J3ECA9
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.

219594:FGF12
gene id: 219594:FGF12
uniprot id: A0A6J3DCB0
uniprot id: A0A6J3DF03
uniprot id: A0A6J3DHU0
uniprot id: A0A6J3DIE3
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

219594:CHMP1A
gene id: 219594:CHMP1A
uniprot id: A0A6J3DPA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF7 family.
messages: Cytoplasm
messages: Endosome membrane
messages: Membrane

219594:ZFYVE27
gene id: 219594:ZFYVE27
uniprot id: A0A6J3D9F7
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Endosome membrane
messages: Membrane
messages: Recycling endosome membrane
messages: growth cone membrane

219594:NDUFA13
gene id: 219594:NDUFA13
uniprot id: A0A6J3ECH8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I NDUFA13 subunit family.
messages: Complex I functions in the transfer of electrons from NADH to the respiratory chain. Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis.
messages: Mitochondrion inner membrane

219594:LETM1
gene id: 219594:LETM1
uniprot id: A0A6J3CY74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LETM1 family.
messages: Membrane
messages: Mitochondrion inner membrane

219594:SLCO4A1
gene id: 219594:SLCO4A1
uniprot id: A0A6J3DY02
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the organo anion transporter (TC 2.A.60) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Secreted

219594:SMPD2
gene id: 219594:SMPD2
uniprot id: A0A6J3E5U2
names: Similarity
messages: Belongs to the neutral sphingomyelinase family.

219594:GPD2
gene id: 219594:GPD2
uniprot id: A0A6J3D3N3
uniprot id: A0A6J3D6R4
names: Function
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Calcium-responsive mitochondrial glycerol-3-phosphate dehydrogenase which seems to be a key component of the pancreatic beta-cell glucose-sensing device.

219594:GHR
gene id: 219594:GHR
uniprot id: A0A6J3EDW2
names: Function
names: Similarity
messages: Belongs to the type I cytokine receptor family. Type 1 subfamily.
messages: The soluble form (GHBP) acts as a reservoir of growth hormone in plasma and may be a modulator/inhibitor of GH signaling.

219594:LOC116494551
gene id: 219594:LOC116494551
uniprot id: A0A6J3DSW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

219594:IL15
gene id: 219594:IL15
uniprot id: A0A6J3CRU2
uniprot id: A0A6J3CY10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-15/IL-21 family.
messages: Secreted

219594:IRX4
gene id: 219594:IRX4
uniprot id: A0A6J3CFP5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/IRO homeobox family.
messages: Nucleus

219594:RRP15
gene id: 219594:RRP15
uniprot id: A0A6J3CU81
names: Similarity
messages: Belongs to the RRP15 family.

219594:GSC
gene id: 219594:GSC
uniprot id: A0A6J3CZJ7
names: Subcellular Location Annotation
messages: Nucleus

219594:LDAH
gene id: 219594:LDAH
uniprot id: A0A6J3CLM8
uniprot id: A0A6J3CRK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AB hydrolase superfamily. LDAH family.
messages: Lipid droplet

219594:IL17C
gene id: 219594:IL17C
uniprot id: A0A6J3DM77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-17 family.
messages: Secreted

219594:TEC
gene id: 219594:TEC
uniprot id: A0A6J3D2I7
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

219594:MMP16
gene id: 219594:MMP16
uniprot id: A0A6J3CEL7
uniprot id: A0A6J3CKV9
names: Similarity
messages: Belongs to the peptidase M10A family.

219594:TMPO
gene id: 219594:TMPO
uniprot id: A0A6J3DTD4
uniprot id: A0A6J3DWD7
uniprot id: A0A6J3DWE7
uniprot id: A0A6J3DXC0
names: Similarity
messages: Belongs to the LEM family.

219594:ROMO1
gene id: 219594:ROMO1
uniprot id: A0A6J3DRX9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGR2 family.
messages: Has antibacterial activity against a variety of bacteria including S.aureus, P.aeruginosa and M.tuberculosis. Acts by inducing bacterial membrane breakage.
messages: Induces production of reactive oxygen species (ROS) which are necessary for cell proliferation. May play a role in inducing oxidative DNA damage and replicative senescence. May play a role in the coordination of mitochondrial morphology and cell proliferation.
messages: Mitochondrion inner membrane

219594:ANAPC2
gene id: 219594:ANAPC2
uniprot id: A0A6J3E3A3
names: Similarity
messages: Belongs to the cullin family.

219594:SOST
gene id: 219594:SOST
uniprot id: A0A6J3E9B5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the sclerostin family.
messages: Interacts with LRP4 (via the extracellular domain); the interaction facilitates the inhibition of Wnt signaling. Interacts with LRP5 (via the first two YWTD-EGF repeat domains); the interaction inhibits Wnt-mediated signaling. Interacts with LRP6.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Negative regulator of bone growth that acts through inhibition of Wnt signaling and bone formation.

219594:B3GNT4
gene id: 219594:B3GNT4
uniprot id: A0A6J3DWA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

219594:ST3GAL5
gene id: 219594:ST3GAL5
uniprot id: A0A6J3CXM0
uniprot id: A0A6J3CZY5
uniprot id: A0A6J3D125
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

219594:TMEM184A
gene id: 219594:TMEM184A
uniprot id: A0A6J3DWP9
names: Subcellular Location Annotation
messages: Membrane

219594:SLCO5A1
gene id: 219594:SLCO5A1
uniprot id: A0A6J3CF29
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the organo anion transporter (TC 2.A.60) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Secreted

219594:PPM1G
gene id: 219594:PPM1G
uniprot id: A0A6J3CUI7
names: Similarity
messages: Belongs to the PP2C family.

219594:NMU
gene id: 219594:NMU
uniprot id: A0A6J3D2G3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NmU family.
messages: Secreted

219594:MKS1
gene id: 219594:MKS1
uniprot id: A0A6J3DZJ0
uniprot id: A0A6J3E3S9
names: Subcellular Location Annotation
messages: cilium basal body

219594:LOC116490286
gene id: 219594:LOC116490286
uniprot id: A0A6J3D6M7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:CCZ1
gene id: 219594:CCZ1
uniprot id: A0A6J3DRH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCZ1 family.
messages: Lysosome membrane

219594:INTS12
gene id: 219594:INTS12
uniprot id: A0A6J3CWI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Integrator subunit 12 family.
messages: Nucleus

219594:MYT1L
gene id: 219594:MYT1L
uniprot id: A0A6J3CQS6
uniprot id: A0A6J3CQT1
uniprot id: A0A6J3CT21
uniprot id: A0A6J3CTI8
uniprot id: A0A6J3CTJ1
uniprot id: A0A6J3CVT2
uniprot id: A0A6J3CVT7
uniprot id: A0A6J3CWX5
uniprot id: A0A6J3CWY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MYT1 family.
messages: Nucleus

219594:ESRRB
gene id: 219594:ESRRB
uniprot id: A0A6J3D313
uniprot id: A0A6J3D3A7
uniprot id: A0A6J3D5K5
uniprot id: A0A6J3D6H0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR3 subfamily.
messages: Nucleus

219594:PGM5
gene id: 219594:PGM5
uniprot id: A0A6J3EGE8
names: Similarity
messages: Belongs to the phosphohexose mutase family.

219594:PATL2
gene id: 219594:PATL2
uniprot id: A0A6J3DHT2
names: Similarity
messages: Belongs to the PAT1 family.

219594:NTS
gene id: 219594:NTS
uniprot id: A0A6J3DLW8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neurotensin family.
messages: Neurotensin may play an endocrine or paracrine role in the regulation of fat metabolism. It causes contraction of smooth muscle.
messages: Secreted
messages: Vesicle
messages: secretory vesicle

219594:EEF2KMT
gene id: 219594:EEF2KMT
uniprot id: A0A6J3DVL3
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. EEF2KMT family.

219594:VEGFD
gene id: 219594:VEGFD
uniprot id: A0A6J3EIV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PDGF/VEGF growth factor family.
messages: Secreted

219594:PDGFC
gene id: 219594:PDGFC
uniprot id: A0A6J3CWZ4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PDGF/VEGF growth factor family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

219594:PRKG1
gene id: 219594:PRKG1
uniprot id: A0A6J3DAP7
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. cGMP subfamily.

219594:HMGB2
gene id: 219594:HMGB2
uniprot id: A0A6J3CZS4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HMGB family.
messages: Chromosome

219594:CRYBA1
gene id: 219594:CRYBA1
uniprot id: A0A6J3DYU7
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

219594:BCAN
gene id: 219594:BCAN
uniprot id: A0A6J3EE61
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:SNX8
gene id: 219594:SNX8
uniprot id: A0A6J3DTB5
uniprot id: A0A6J3DVG0
uniprot id: A0A6J3DWA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Membrane

219594:IRF2BP2
gene id: 219594:IRF2BP2
uniprot id: A0A6J3CV38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IRF2BP family.
messages: Nucleus

219594:LOC116493990
gene id: 219594:LOC116493990
uniprot id: A0A6J3DNK4
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane
messages: Membrane

219594:OLFM3
gene id: 219594:OLFM3
uniprot id: A0A6J3D9X2
uniprot id: A0A6J3DDJ0
uniprot id: A0A6J3DFP4
names: Subcellular Location Annotation
messages: Secreted
messages: Synapse

219594:CLRN2
gene id: 219594:CLRN2
uniprot id: A0A6J3CZ56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the clarin family.
messages: Membrane

219594:GFRAL
gene id: 219594:GFRAL
uniprot id: A0A6J3CMQ4
uniprot id: A0A6J3CPK0
names: Similarity
messages: Belongs to the GDNFR family.

219594:LIG3
gene id: 219594:LIG3
uniprot id: A0A6J3E0N0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP-dependent DNA ligase family.
messages: Nucleus

219594:TBCD
gene id: 219594:TBCD
uniprot id: A0A6J3DXW9
names: Similarity
messages: Belongs to the TBCD family.

219594:TRPV4
gene id: 219594:TRPV4
uniprot id: A0A6J3DWI5
names: Subcellular Location Annotation
messages: Membrane

219594:TM4SF1
gene id: 219594:TM4SF1
uniprot id: A0A6J3DD13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L6 tetraspanin family.
messages: Membrane

219594:LOC116485898
gene id: 219594:LOC116485898
uniprot id: A0A6J3CL75
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UQCRB/QCR7 family.
messages: Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation.
messages: Mitochondrion inner membrane

219594:TACC3
gene id: 219594:TACC3
uniprot id: A0A6J3CXZ5
uniprot id: A0A6J3CYA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACC family.
messages: Cytoplasm

219594:LOC116495451
gene id: 219594:LOC116495451
uniprot id: A0A6J3DV43
names: Function
names: Similarity
messages: Belongs to the parvalbumin family.
messages: In muscle, parvalbumin is thought to be involved in relaxation after contraction. It binds two calcium ions.

219594:BCO2
gene id: 219594:BCO2
uniprot id: A0A6J3E264
uniprot id: A0A6J3E3K1
uniprot id: A0A6J3E759
uniprot id: A0A6J3E8G1
names: Similarity
messages: Belongs to the carotenoid oxygenase family.

219594:LOC116497345
gene id: 219594:LOC116497345
uniprot id: A0A6J3E1G5
names: Subcellular Location Annotation
messages: Membrane

219594:ALDH1A3
gene id: 219594:ALDH1A3
uniprot id: A0A6J3DN26
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

219594:ACTR8
gene id: 219594:ACTR8
uniprot id: A0A6J3DI14
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the actin family. ARP8 subfamily.
messages: Chromosome
messages: Component of the chromatin remodeling INO80 complex; specifically part of a complex module associated with the DBINO domain of INO80. Exists as monomers and dimers, but the dimer is most probably the biologically relevant form required for stable interactions with histones that exploits the twofold symmetry of the nucleosome core.
messages: Nucleus
messages: Plays an important role in the functional organization of mitotic chromosomes. Exhibits low basal ATPase activity, and unable to polymerize.
messages: Proposed core component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair.

219594:LOC116491391
gene id: 219594:LOC116491391
uniprot id: A0A6J3DCL7
names: Similarity
messages: Belongs to the cystatin family.

219594:LOC116488615
gene id: 219594:LOC116488615
uniprot id: A0A6J3CVQ4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the intercrine alpha (chemokine CxC) family.
messages: Homodimer.
messages: Secreted

219594:OSGEPL1
gene id: 219594:OSGEPL1
uniprot id: A0A6J3D3Z3
uniprot id: A0A6J3D9W2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 divalent metal cation per subunit.
messages: Mitochondrion
messages: Monomer.
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in mitochondrial tRNAs that read codons beginning with adenine. Probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Involved in mitochondrial genome maintenance.

219594:NEURL2
gene id: 219594:NEURL2
uniprot id: A0A6J3DXT3
names: Subcellular Location Annotation
messages: Cytoplasm

219594:MMACHC
gene id: 219594:MMACHC
uniprot id: A0A6J3DEH7
names: Similarity
messages: Belongs to the MMACHC family.

219594:GSTK1
gene id: 219594:GSTK1
uniprot id: A0A6J3EPJ8
names: Similarity
messages: Belongs to the GST superfamily. Kappa family.

219594:GALC
gene id: 219594:GALC
uniprot id: A0A6J3D0E2
uniprot id: A0A6J3D2U4
names: Similarity
messages: Belongs to the glycosyl hydrolase 59 family.

219594:RPL13
gene id: 219594:RPL13
uniprot id: A0A6J3DIT3
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL13 family.

219594:GTF2A1L
gene id: 219594:GTF2A1L
uniprot id: A0A6J3CTN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFIIA subunit 1 family.
messages: Nucleus

219594:HYAL2
gene id: 219594:HYAL2
uniprot id: A0A6J3DHW8
names: Similarity
messages: Belongs to the glycosyl hydrolase 56 family.

219594:TIMM21
gene id: 219594:TIMM21
uniprot id: A0A6J3CJ18
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TIM21 family.
messages: Component of the TIM23 complex.
messages: Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.
messages: Membrane
messages: Mitochondrion inner membrane
messages: Mitochondrion membrane

219594:SPPL2B
gene id: 219594:SPPL2B
uniprot id: A0A6J3E8G7
uniprot id: A0A6J3EBH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A22B family.
messages: Endosome membrane
messages: Lysosome membrane
messages: Membrane

219594:LOC116491479
gene id: 219594:LOC116491479
uniprot id: A0A6J3D7F1
names: Similarity
messages: Belongs to the DEAD box helicase family. DDX21/DDX50 subfamily.

219594:PAX6
gene id: 219594:PAX6
uniprot id: A0A6J3CZF9
uniprot id: A0A6J3D1V9
uniprot id: A0A6J3D1Z8
uniprot id: A0A6J3D4E5
uniprot id: A0A6J3D4F0
uniprot id: A0A6J3D5D2
uniprot id: A0A6J3D5D7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paired homeobox family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

219594:LOC116497897
gene id: 219594:LOC116497897
uniprot id: A0A6J3E8V0
names: Subcellular Location Annotation
messages: Membrane

219594:CTNNA1
gene id: 219594:CTNNA1
uniprot id: A0A6J3DM54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vinculin/alpha-catenin family.
messages: Cell membrane
messages: Membrane
messages: adherens junction
messages: cytoskeleton

219594:GTF2H1
gene id: 219594:GTF2H1
uniprot id: A0A6J3CX12
uniprot id: A0A6J3CZK7
uniprot id: A0A6J3D1V1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFB1 family.
messages: Nucleus

219594:CAMK2A
gene id: 219594:CAMK2A
uniprot id: A0A6J3DQG0
uniprot id: A0A6J3DSH0
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily.

219594:RHOT1
gene id: 219594:RHOT1
uniprot id: A0A6J3DVR3
uniprot id: A0A6J3DZX1
uniprot id: A0A6J3E0Q7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial Rho GTPase family.
messages: Membrane
messages: Mitochondrial GTPase involved in mitochondrial trafficking.
messages: Mitochondrion outer membrane

219594:RAD17
gene id: 219594:RAD17
uniprot id: A0A6J3ELX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the rad17/RAD24 family.
messages: Nucleus

219594:GABRA6
gene id: 219594:GABRA6
uniprot id: A0A6J3DU38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

219594:OGFR
gene id: 219594:OGFR
uniprot id: A0A6J3DX88
uniprot id: A0A6J3DYA7
names: Similarity
messages: Belongs to the opioid growth factor receptor family.

219594:NFYA
gene id: 219594:NFYA
uniprot id: A0A6J3E5S0
uniprot id: A0A6J3E5S5
uniprot id: A0A6J3E777
uniprot id: A0A6J3E784
uniprot id: A0A6J3EA90
uniprot id: A0A6J3EAV8
uniprot id: A0A6J3ECE3
uniprot id: A0A6J3ECF1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NFYA/HAP2 subunit family.
messages: Component of the sequence-specific heterotrimeric transcription factor (NF-Y) which specifically recognizes a 5'-CCAAT-3' box motif found in the promoters of its target genes.
messages: Heterotrimer.
messages: Nucleus

219594:SLC50A1
gene id: 219594:SLC50A1
uniprot id: A0A6J3EEW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SWEET sugar transporter family.
messages: Membrane

219594:CAND1
gene id: 219594:CAND1
uniprot id: A0A6J3CRV0
names: Similarity
messages: Belongs to the CAND family.

219594:EVA1B
gene id: 219594:EVA1B
uniprot id: A0A6J3E900
names: Similarity
messages: Belongs to the EVA1 family.

219594:SMU1
gene id: 219594:SMU1
uniprot id: A0A6J3EIC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat SMU1 family.
messages: Nucleus speckle

219594:LOC116494706
gene id: 219594:LOC116494706
uniprot id: A0A6J3DME1
uniprot id: A0A6J3DRQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Nucleus

219594:SNTB1
gene id: 219594:SNTB1
uniprot id: A0A6J3CL73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the syntrophin family.
messages: Cell junction
messages: cytoskeleton

219594:ECHDC1
gene id: 219594:ECHDC1
uniprot id: A0A6J3CLK0
uniprot id: A0A6J3CP73
uniprot id: A0A6J3CSH7
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

219594:SLC7A9
gene id: 219594:SLC7A9
uniprot id: A0A6J3DQX7
names: Subcellular Location Annotation
messages: Membrane

219594:EFNA2
gene id: 219594:EFNA2
uniprot id: A0A6J3EBV6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ephrin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

219594:ELF3
gene id: 219594:ELF3
uniprot id: A0A6J3E7W8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

219594:DGKQ
gene id: 219594:DGKQ
uniprot id: A0A6J3EGH6
uniprot id: A0A6J3EK59
uniprot id: A0A6J3ELT1
names: Similarity
messages: Belongs to the eukaryotic diacylglycerol kinase family.

219594:UFL1
gene id: 219594:UFL1
uniprot id: A0A6J3CP82
names: Similarity
messages: Belongs to the UFL1 family.

219594:SMC4
gene id: 219594:SMC4
uniprot id: A0A6J3DEP5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMC family. SMC4 subfamily.
messages: Chromosome
messages: Nucleus

219594:UMODL1
gene id: 219594:UMODL1
uniprot id: A0A6J3CE76
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:RPS6
gene id: 219594:RPS6
uniprot id: A0A6J3EK38
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS6 family.

219594:NT5C3A
gene id: 219594:NT5C3A
uniprot id: A0A6J3CHY2
uniprot id: A0A6J3CKX2
uniprot id: A0A6J3CKX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrimidine 5'-nucleotidase family.
messages: Cytoplasm

219594:VPS26A
gene id: 219594:VPS26A
uniprot id: A0A6J3DD27
names: Similarity
messages: Belongs to the VPS26 family.

219594:LOC116486741
gene id: 219594:LOC116486741
uniprot id: A0A6J3CJC1
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

219594:LOC116498198
gene id: 219594:LOC116498198
uniprot id: A0A6J3E8Y0
names: Subcellular Location Annotation
messages: Nucleus

219594:GPATCH1
gene id: 219594:GPATCH1
uniprot id: A0A6J3DPV0
names: Similarity
messages: Belongs to the GPATCH1 family.

219594:GAS8
gene id: 219594:GAS8
uniprot id: A0A6J3DQF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DRC4 family.
messages: flagellum axoneme

219594:SARS1
gene id: 219594:SARS1
uniprot id: A0A6J3E7D1
uniprot id: A0A6J3EAE3
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.

219594:MTX2
gene id: 219594:MTX2
uniprot id: A0A6J3D9T2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metaxin family.
messages: Membrane
messages: Mitochondrion outer membrane

219594:LYG2
gene id: 219594:LYG2
uniprot id: A0A6J3EJM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 23 family.
messages: Secreted

219594:FOXN2
gene id: 219594:FOXN2
uniprot id: A0A6J3CTH2
uniprot id: A0A6J3CVR0
names: Subcellular Location Annotation
messages: Nucleus

219594:UGP2
gene id: 219594:UGP2
uniprot id: A0A6J3CMQ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UDPGP type 1 family.
messages: Homooctamer.
messages: UTP--glucose-1-phosphate uridylyltransferase catalyzing the conversion of glucose-1-phosphate into UDP-glucose, a crucial precursor for the production of glycogen.

219594:GYS2
gene id: 219594:GYS2
uniprot id: A0A6J3EH13
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 3 family.
messages: Transfers the glycosyl residue from UDP-Glc to the non-reducing end of alpha-1,4-glucan.

219594:LOC116497614
gene id: 219594:LOC116497614
uniprot id: A0A6J3E5I0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein arginine deiminase family.
messages: Cytoplasm

219594:LOC116496449
gene id: 219594:LOC116496449
uniprot id: A0A6J3DVP1
uniprot id: A0A6J3DZU9
uniprot id: A0A6J3E0N1
uniprot id: A0A6J3E1T0
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

219594:SLX4
gene id: 219594:SLX4
uniprot id: A0A6J3DQ53
uniprot id: A0A6J3DSF0
names: Similarity
messages: Belongs to the SLX4 family.

219594:IL17REL
gene id: 219594:IL17REL
uniprot id: A0A6J3DZ21
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

219594:ATP6V0E1
gene id: 219594:ATP6V0E1
uniprot id: A0A6J3DQX3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the V-ATPase e1/e2 subunit family.
messages: Membrane
messages: Subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.

219594:ATP13A5
gene id: 219594:ATP13A5
uniprot id: A0A6J3DCL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily.
messages: Membrane

219594:ADGRG3
gene id: 219594:ADGRG3
uniprot id: A0A6J3DNV8
names: Subcellular Location Annotation
messages: Membrane

219594:LOC116498831
gene id: 219594:LOC116498831
uniprot id: A0A6J3ECV4
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS10 family.

219594:YPEL1
gene id: 219594:YPEL1
uniprot id: A0A6J3DZF6
names: Similarity
messages: Belongs to the yippee family.

219594:TRAM1
gene id: 219594:TRAM1
uniprot id: A0A6J3CFJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAM family.
messages: Membrane

219594:GPR37L1
gene id: 219594:GPR37L1
uniprot id: A0A6J3EAK3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

219594:ISYNA1
gene id: 219594:ISYNA1
uniprot id: A0A6J3E7Q6
uniprot id: A0A6J3ECC1
names: Similarity
messages: Belongs to the myo-inositol 1-phosphate synthase family.

219594:SLC25A5
gene id: 219594:SLC25A5
uniprot id: A0A6J3DKF3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Catalyzes the exchange of ADP and ATP across the membrane.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Monomer.

219594:SBDS
gene id: 219594:SBDS
uniprot id: A0A6J3E163
names: Function
names: Similarity
messages: Belongs to the SDO1/SBDS family.
messages: Required for the assembly of mature ribosomes and ribosome biogenesis. Together with EFL1, triggers the GTP-dependent release of EIF6 from 60S pre-ribosomes in the cytoplasm, thereby activating ribosomes for translation competence by allowing 80S ribosome assembly and facilitating EIF6 recycling to the nucleus, where it is required for 60S rRNA processing and nuclear export. Required for normal levels of protein synthesis. May play a role in cellular stress resistance. May play a role in cellular response to DNA damage. May play a role in cell proliferation.

219594:LOC116497277
gene id: 219594:LOC116497277
uniprot id: A0A6J3E178
names: Subcellular Location Annotation
messages: Membrane
messages: cytoskeleton

219594:GALNT11
gene id: 219594:GALNT11
uniprot id: A0A6J3CJW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

219594:FAM174C
gene id: 219594:FAM174C
uniprot id: A0A6J3ECK8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM174 family.
messages: Membrane

219594:NDUFB6
gene id: 219594:NDUFB6
uniprot id: A0A6J3DQJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFB6 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

219594:GLIS3
gene id: 219594:GLIS3
uniprot id: A0A6J3EFN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GLI C2H2-type zinc-finger protein family.
messages: Nucleus

219594:LOC116487531
gene id: 219594:LOC116487531
uniprot id: A0A6J3CMZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. Very large inducible GTPase (VLIG) family.
messages: Nucleus

219594:NKX2-8
gene id: 219594:NKX2-8
uniprot id: A0A6J3CYY9
names: Subcellular Location Annotation
messages: Nucleus

219594:DUSP8
gene id: 219594:DUSP8
uniprot id: A0A6J3CYI9
uniprot id: A0A6J3D142
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.

219594:MAGI3
gene id: 219594:MAGI3
uniprot id: A0A6J3E6G4
uniprot id: A0A6J3EBI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAGUK family.
messages: Cell membrane
messages: Membrane
messages: tight junction

219594:YIPF6
gene id: 219594:YIPF6
uniprot id: A0A6J3DNP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YIP1 family.
messages: Membrane

219594:EN1
gene id: 219594:EN1
uniprot id: A0A6J3DAB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Engrailed homeobox family.
messages: Nucleus

219594:ATP5ME
gene id: 219594:ATP5ME
uniprot id: A0A6J3EIC3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase e subunit family.
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel.
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. Minor subunit located with subunit a in the membrane.
messages: Mitochondrion inner membrane

219594:PPME1
gene id: 219594:PPME1
uniprot id: A0A6J3CYZ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the AB hydrolase superfamily.
messages: Binds PPP2CA and PPP2CB.
messages: Demethylates proteins that have been reversibly carboxymethylated. Demethylates PPP2CB (in vitro) and PPP2CA. Binding to PPP2CA displaces the manganese ion and inactivates the enzyme.

219594:MCRIP1
gene id: 219594:MCRIP1
uniprot id: A0A6J3E1J7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCRIP family.
messages: Nucleus
messages: Stress granule

219594:MEA1
gene id: 219594:MEA1
uniprot id: A0A6J3CS51
names: Function
messages: May play an important role in spermatogenesis and/or testis development.

219594:SPRY2
gene id: 219594:SPRY2
uniprot id: A0A6J3E6H2
names: Similarity
messages: Belongs to the sprouty family.

219594:ETV4
gene id: 219594:ETV4
uniprot id: A0A6J3E4T9
uniprot id: A0A6J3E977
uniprot id: A0A6J3E9U7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

219594:ETFRF1
gene id: 219594:ETFRF1
uniprot id: A0A6J3CJV0
names: Similarity
messages: Belongs to the complex I LYR family.

219594:FKBP5
gene id: 219594:FKBP5
uniprot id: A0A6J3EAG3
names: Subcellular Location Annotation
messages: Nucleus

219594:SOD1
gene id: 219594:SOD1
uniprot id: A0A6J3EK55
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Cu-Zn superoxide dismutase family.
messages: Binds 1 copper ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

219594:GPR20
gene id: 219594:GPR20
uniprot id: A0A6J3CNY3
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

219594:CPO
gene id: 219594:CPO
uniprot id: A0A6J3D889
names: Similarity
messages: Belongs to the peptidase M14 family.

219594:ATG7
gene id: 219594:ATG7
uniprot id: A0A6J3DL57
uniprot id: A0A6J3DLM4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATG7 family.
messages: Cytoplasm
messages: E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. Modulates p53/TP53 activity to regulate cell cycle and survival during metabolic stress.
messages: Homodimer.
messages: Preautophagosomal structure

219594:LOC116492195
gene id: 219594:LOC116492195
uniprot id: A0A6J3DGP1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:GCLM
gene id: 219594:GCLM
uniprot id: A0A6J3DCR7
names: Similarity
names: Subunit
messages: Belongs to the aldo/keto reductase family. Glutamate--cysteine ligase light chain subfamily.
messages: Heterodimer of a catalytic heavy chain and a regulatory light chain.

219594:KCNQ2
gene id: 219594:KCNQ2
uniprot id: A0A6J3DRB2
uniprot id: A0A6J3DRB6
uniprot id: A0A6J3DTI7
uniprot id: A0A6J3DTJ1
uniprot id: A0A6J3DVN9
uniprot id: A0A6J3DVP4
uniprot id: A0A6J3DWI2
uniprot id: A0A6J3DWI6
uniprot id: A0A6J3DXG8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

219594:PLBD2
gene id: 219594:PLBD2
uniprot id: A0A6J3E0X4
names: Function
names: Similarity
messages: Belongs to the phospholipase B-like family.
messages: Putative phospholipase.

219594:TBX15
gene id: 219594:TBX15
uniprot id: A0A6J3E5S4
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

219594:LOC116496467
gene id: 219594:LOC116496467
uniprot id: A0A6J3DZY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CYBC1 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

219594:FEZ2
gene id: 219594:FEZ2
uniprot id: A0A6J3CN41
uniprot id: A0A6J3CU64
names: Similarity
messages: Belongs to the zygin family.

219594:LOC116491641
gene id: 219594:LOC116491641
uniprot id: A0A6J3DDY6
uniprot id: A0A6J3DE91
names: Similarity
messages: Belongs to the cytochrome P450 family.

219594:LCAT
gene id: 219594:LCAT
uniprot id: A0A6J3DLT4
names: Similarity
messages: Belongs to the AB hydrolase superfamily. Lipase family.

219594:LOC116500088
gene id: 219594:LOC116500088
uniprot id: A0A6J3EG39
names: Subcellular Location Annotation
messages: Nucleus

219594:ARPP19
gene id: 219594:ARPP19
uniprot id: A0A6J3DMB1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endosulfine family.
messages: Cytoplasm
messages: Protein phosphatase inhibitor that specifically inhibits protein phosphatase 2A (PP2A) during mitosis.

219594:MFSD11
gene id: 219594:MFSD11
uniprot id: A0A6J3DVX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the unc-93 family.
messages: Membrane

219594:CDKN1A
gene id: 219594:CDKN1A
uniprot id: A0A6J3EBM1
names: Similarity
messages: Belongs to the CDI family.

219594:LOC116494961
gene id: 219594:LOC116494961
uniprot id: A0A6J3DQS7
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.

219594:CERS5
gene id: 219594:CERS5
uniprot id: A0A6J3EBK7
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Nucleus

219594:LOC116491839
gene id: 219594:LOC116491839
uniprot id: A0A6J3DFA9
names: Similarity
messages: Belongs to the cytochrome P450 family.

219594:LOC116487812
gene id: 219594:LOC116487812
uniprot id: A0A6J3CPD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PET117 family.
messages: Mitochondrion

219594:FOXP1
gene id: 219594:FOXP1
uniprot id: A0A6J3DJB6
uniprot id: A0A6J3DKX5
names: Subcellular Location Annotation
messages: Nucleus

219594:EBNA1BP2
gene id: 219594:EBNA1BP2
uniprot id: A0A6J3DDK2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EBP2 family.
messages: Required for the processing of the 27S pre-rRNA.
messages: nucleolus

219594:LOC116491677
gene id: 219594:LOC116491677
uniprot id: A0A6J3DEC6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

219594:CDC37L1
gene id: 219594:CDC37L1
uniprot id: A0A6J3EI28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDC37 family.
messages: Cytoplasm

219594:TRAPPC2
gene id: 219594:TRAPPC2
uniprot id: A0A6J3DFB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAPP small subunits family. Sedlin subfamily.
messages: perinuclear region

219594:OLFML2B
gene id: 219594:OLFML2B
uniprot id: A0A6J3DH58
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:TBX3
gene id: 219594:TBX3
uniprot id: A0A6J3DZ50
uniprot id: A0A6J3E065
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

219594:CFAP97
gene id: 219594:CFAP97
uniprot id: A0A6J3CVH4
names: Similarity
messages: Belongs to the CFAP97 family.

219594:TNFRSF19
gene id: 219594:TNFRSF19
uniprot id: A0A6J3EPI0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:LOC116491477
gene id: 219594:LOC116491477
uniprot id: A0A6J3D7E7
uniprot id: A0A6J3DDD6
names: Domain
names: Similarity
messages: A pair of annexin repeats may form one binding site for calcium and phospholipid.
messages: Belongs to the annexin family.

219594:RPS6KB1
gene id: 219594:RPS6KB1
uniprot id: A0A6J3E0W5
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.

219594:LPCAT3
gene id: 219594:LPCAT3
uniprot id: A0A6J3ENN0
names: Subcellular Location Annotation
messages: Membrane

219594:SEZ6L
gene id: 219594:SEZ6L
uniprot id: A0A6J3DUA2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:CILP2
gene id: 219594:CILP2
uniprot id: A0A6J3ECU1
names: Subcellular Location Annotation
messages: extracellular matrix

219594:POU4F1
gene id: 219594:POU4F1
uniprot id: A0A6J3E8C3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POU transcription factor family.
messages: Nucleus

219594:TM9SF4
gene id: 219594:TM9SF4
uniprot id: A0A6J3DU81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family.
messages: Membrane

219594:HMX1
gene id: 219594:HMX1
uniprot id: A0A6J3D181
names: Subcellular Location Annotation
messages: Nucleus

219594:LOC116498582
gene id: 219594:LOC116498582
uniprot id: A0A6J3E573
names: Similarity
names: Subunit
messages: Belongs to the avian keratin family.
messages: The avian keratins (F-ker, S-ker, C-ker and B-ker) are a complex mixture of very similar polypeptides.

219594:TNN
gene id: 219594:TNN
uniprot id: A0A6J3DDY9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tenascin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

219594:PDIK1L
gene id: 219594:PDIK1L
uniprot id: A0A6J3EA86
names: Similarity
messages: Belongs to the protein kinase superfamily.

219594:MGAT5B
gene id: 219594:MGAT5B
uniprot id: A0A6J3DWL4
uniprot id: A0A6J3E0S0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 18 family.
messages: Golgi apparatus membrane
messages: Membrane

219594:MTERF2
gene id: 219594:MTERF2
uniprot id: A0A6J3ERT9
names: Similarity
messages: Belongs to the mTERF family.

219594:RRP7A
gene id: 219594:RRP7A
uniprot id: A0A6J3DT18
names: Similarity
messages: Belongs to the RRP7 family.

219594:KIF21A
gene id: 219594:KIF21A
uniprot id: A0A6J3DBT9
uniprot id: A0A6J3DBU9
uniprot id: A0A6J3DBV7
uniprot id: A0A6J3DEE3
uniprot id: A0A6J3DEJ3
uniprot id: A0A6J3DFQ0
uniprot id: A0A6J3DHV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
messages: cytoskeleton

219594:CBFB
gene id: 219594:CBFB
uniprot id: A0A6J3DJX9
uniprot id: A0A6J3DP64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CBF-beta family.
messages: Nucleus

219594:ACTL6A
gene id: 219594:ACTL6A
uniprot id: A0A6J3DGX2
names: Similarity
messages: Belongs to the actin family.

219594:DDO
gene id: 219594:DDO
uniprot id: A0A6J3CMX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DAMOX/DASOX family.
messages: Peroxisome

219594:SULT6B1
gene id: 219594:SULT6B1
uniprot id: A0A6J3CWD7
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

219594:INSM1
gene id: 219594:INSM1
uniprot id: A0A6J3CW99
names: Subcellular Location Annotation
messages: Nucleus

219594:DIP2C
gene id: 219594:DIP2C
uniprot id: A0A6J3CEG8
uniprot id: A0A6J3CG40
uniprot id: A0A6J3CH27
uniprot id: A0A6J3CJ15
uniprot id: A0A6J3CKQ4
names: Similarity
messages: Belongs to the DIP2 family.

219594:MRE11
gene id: 219594:MRE11
uniprot id: A0A6J3E0B2
uniprot id: A0A6J3E1R1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MRE11/RAD32 family.
messages: Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.
messages: Nucleus

219594:GSK3B
gene id: 219594:GSK3B
uniprot id: A0A6J3DLD1
uniprot id: A0A6J3DNS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. GSK-3 subfamily.
messages: Cytoplasm
messages: Nucleus

219594:FAM135A
gene id: 219594:FAM135A
uniprot id: A0A6J3CM56
uniprot id: A0A6J3CNX2
names: Similarity
messages: Belongs to the FAM135 family.

219594:ASPA
gene id: 219594:ASPA
uniprot id: A0A6J3E0R9
names: Cofactor
names: Similarity
messages: Belongs to the AspA/AstE family. Aspartoacylase subfamily.
messages: Binds 1 zinc ion per subunit.

219594:CLTCL1
gene id: 219594:CLTCL1
uniprot id: A0A6J3DZT3
uniprot id: A0A6J3E0W0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the clathrin heavy chain family.
messages: Clathrin is the major protein of the polyhedral coat of coated pits and vesicles.
messages: Cytoplasmic vesicle membrane
messages: Membrane
messages: coated pit

219594:DNAJB12
gene id: 219594:DNAJB12
uniprot id: A0A6J3DDH3
names: Subcellular Location Annotation
messages: Membrane

219594:PSMD9
gene id: 219594:PSMD9
uniprot id: A0A6J3DVR2
names: Similarity
messages: Belongs to the proteasome subunit p27 family.

219594:SRPX
gene id: 219594:SRPX
uniprot id: A0A6J3DQ69
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:NPC1L1
gene id: 219594:NPC1L1
uniprot id: A0A6J3E869
names: Similarity
messages: Belongs to the patched family.

219594:DNA2
gene id: 219594:DNA2
uniprot id: A0A6J3D6G0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA2/NAM7 helicase family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Key enzyme involved in DNA replication and DNA repair. Involved in Okazaki fragments processing by cleaving long flaps that escape FEN1: flaps that are longer than 27 nucleotides are coated by replication protein A complex (RPA), leading to recruit DNA2 which cleaves the flap until it is too short to bind RPA and becomes a substrate for FEN1. Also involved in 5'-end resection of DNA during double-strand break (DSB) repair by mediating the cleavage of 5'-ssDNA.
messages: Mitochondrion
messages: Nucleus

219594:FIP1L1
gene id: 219594:FIP1L1
uniprot id: A0A6J3CS18
uniprot id: A0A6J3CUC7
uniprot id: A0A6J3CUV1
uniprot id: A0A6J3CX53
uniprot id: A0A6J3CY96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FIP1 family.
messages: Nucleus

219594:LOC116500116
gene id: 219594:LOC116500116
uniprot id: A0A6J3EG72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:ETV6
gene id: 219594:ETV6
uniprot id: A0A6J3E6Y2
uniprot id: A0A6J3EBY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

219594:LOC116489632
gene id: 219594:LOC116489632
uniprot id: A0A6J3D337
uniprot id: A0A6J3D462
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM263 family.
messages: Membrane

219594:NAV1
gene id: 219594:NAV1
uniprot id: A0A6J3E7D6
uniprot id: A0A6J3EAE8
names: Similarity
messages: Belongs to the Nav/unc-53 family.

219594:AMER2
gene id: 219594:AMER2
uniprot id: A0A6J3EQ79
names: Similarity
messages: Belongs to the Amer family.

219594:NRN1
gene id: 219594:NRN1
uniprot id: A0A6J3CMJ4
names: Similarity
messages: Belongs to the neuritin family.

219594:RNF170
gene id: 219594:RNF170
uniprot id: A0A6J3ED27
uniprot id: A0A6J3EHW9
uniprot id: A0A6J3EJV4
names: Subcellular Location Annotation
messages: Membrane

219594:IBSP
gene id: 219594:IBSP
uniprot id: A0A6J3D1H0
names: Function
names: Subcellular Location Annotation
messages: Binds tightly to hydroxyapatite. Appears to form an integral part of the mineralized matrix. Probably important to cell-matrix interaction. Promotes Arg-Gly-Asp-dependent cell attachment.
messages: Secreted

219594:CDC25A
gene id: 219594:CDC25A
uniprot id: A0A6J3CIU8
names: Function
names: Similarity
messages: Belongs to the MPI phosphatase family.
messages: Functions as a dosage-dependent inducer in mitotic control. Tyrosine protein phosphatase required for progression of the cell cycle.

219594:DNAJC24
gene id: 219594:DNAJC24
uniprot id: A0A6J3D1C8
names: Similarity
messages: Belongs to the DPH4 family.

219594:LOC116490632
gene id: 219594:LOC116490632
uniprot id: A0A6J3D624
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.

219594:GLS
gene id: 219594:GLS
uniprot id: A0A6J3D554
names: Similarity
messages: Belongs to the glutaminase family.

219594:SLIT3
gene id: 219594:SLIT3
uniprot id: A0A6J3DSA4
uniprot id: A0A6J3DTD9
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

219594:SFTPD
gene id: 219594:SFTPD
uniprot id: A0A6J3DCG9
names: Similarity
names: Subunit
messages: Belongs to the SFTPD family.
messages: Oligomeric complex of 4 set of homotrimers.

219594:SEPTIN2
gene id: 219594:SEPTIN2
uniprot id: A0A6J3DI94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
messages: Cleavage furrow
messages: Midbody
messages: cilium membrane
messages: spindle

219594:DOHH
gene id: 219594:DOHH
uniprot id: A0A6J3E7E1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the deoxyhypusine hydroxylase family.
messages: Binds 2 Fe(2+) ions per subunit.
messages: Catalyzes the hydroxylation of the N(6)-(4-aminobutyl)-L-lysine intermediate to form hypusine, an essential post-translational modification only found in mature eIF-5A factor.

219594:CCNC
gene id: 219594:CCNC
uniprot id: A0A6J3CUM2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cyclin family. Cyclin C subfamily.
messages: Component of the Mediator complex, a coactivator involved in regulated gene transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. Binds to and activates cyclin-dependent kinase CDK8 that phosphorylates the CTD (C-terminal domain) of the large subunit of RNA polymerase II (RNAp II), which may inhibit the formation of a transcription initiation complex.
messages: Nucleus

219594:LOC116501375
gene id: 219594:LOC116501375
uniprot id: A0A6J3EGC2
uniprot id: A0A6J3ELN8
names: Similarity
messages: Belongs to the RICTOR family.

219594:SUGCT
gene id: 219594:SUGCT
uniprot id: A0A6J3CJ48
uniprot id: A0A6J3CLT1
uniprot id: A0A6J3CNR0
names: Similarity
messages: Belongs to the CoA-transferase III family.

219594:TAF13
gene id: 219594:TAF13
uniprot id: A0A6J3DYF6
names: Subcellular Location Annotation
messages: Nucleus

219594:LOC116491251
gene id: 219594:LOC116491251
uniprot id: A0A6J3DBX3
names: Similarity
messages: Belongs to the VPS10-related sortilin family. SORCS subfamily.

219594:MED18
gene id: 219594:MED18
uniprot id: A0A6J3EJ31
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 18 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

219594:PIK3C2G
gene id: 219594:PIK3C2G
uniprot id: A0A6J3EQF5
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.

219594:LOC116487604
gene id: 219594:LOC116487604
uniprot id: A0A6J3CT93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CENP-Q/OKP1 family.
messages: Nucleus

219594:ADAMTS1
gene id: 219594:ADAMTS1
uniprot id: A0A6J3E1F7
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

219594:SKA1
gene id: 219594:SKA1
uniprot id: A0A6J3EJ85
names: Similarity
messages: Belongs to the SKA1 family.

219594:ILDR2
gene id: 219594:ILDR2
uniprot id: A0A6J3EIT6
uniprot id: A0A6J3EP24
uniprot id: A0A6J3EP47
uniprot id: A0A6J3EQI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. LISCH7 family.
messages: Membrane
messages: tight junction

219594:PPIB
gene id: 219594:PPIB
uniprot id: A0A6J3DK20
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

219594:MST1R
gene id: 219594:MST1R
uniprot id: A0A6J3DKW5
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

219594:TYW3
gene id: 219594:TYW3
uniprot id: A0A6J3DAE3
names: Function
names: Similarity
messages: Belongs to the TYW3 family.
messages: Probable S-adenosyl-L-methionine-dependent methyltransferase that acts as a component of the wybutosine biosynthesis pathway. Wybutosine is a hyper modified guanosine with a tricyclic base found at the 3'-position adjacent to the anticodon of eukaryotic phenylalanine tRNA.

219594:FANCM
gene id: 219594:FANCM
uniprot id: A0A6J3D3B6
names: Similarity
messages: Belongs to the DEAD box helicase family. DEAH subfamily. FANCM sub-subfamily.

219594:LOC116494045
gene id: 219594:LOC116494045
uniprot id: A0A6J3DNS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

219594:CLDN14
gene id: 219594:CLDN14
uniprot id: A0A6J3EJS9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

219594:ATP6V0D1
gene id: 219594:ATP6V0D1
uniprot id: A0A6J3DNF2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the V-ATPase V0D/AC39 subunit family.
messages: Subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.

219594:PSMA7
gene id: 219594:PSMA7
uniprot id: A0A6J3DW84
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Cytoplasm
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.

219594:PTGER4
gene id: 219594:PTGER4
uniprot id: A0A6J3EIM5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Interacts with FEM1A.
messages: Membrane
messages: Receptor for prostaglandin E2 (PGE2). The activity of this receptor is mediated by G(s) proteins that stimulate adenylate cyclase. Has a relaxing effect on smooth muscle. May play an important role in regulating renal hemodynamics, intestinal epithelial transport, adrenal aldosterone secretion, and uterine function.

219594:TRADD
gene id: 219594:TRADD
uniprot id: A0A6J3DQ17
names: Subcellular Location Annotation
messages: Nucleus
messages: cytoskeleton

219594:LOC116501325
gene id: 219594:LOC116501325
uniprot id: A0A6J3ELI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:DCBLD1
gene id: 219594:DCBLD1
uniprot id: A0A6J3CRD2
uniprot id: A0A6J3CUC8
uniprot id: A0A6J3CVH3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:FSTL1
gene id: 219594:FSTL1
uniprot id: A0A6J3CSG7
names: Subcellular Location Annotation
messages: Secreted

219594:LPIN2
gene id: 219594:LPIN2
uniprot id: A0A6J3CMB3
names: Similarity
messages: Belongs to the lipin family.

219594:LUM
gene id: 219594:LUM
uniprot id: A0A6J3E0M2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class II subfamily.
messages: Binds to laminin.
messages: extracellular matrix

219594:NUP93
gene id: 219594:NUP93
uniprot id: A0A6J3DLL4
uniprot id: A0A6J3DLL8
uniprot id: A0A6J3DN95
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleoporin interacting component (NIC) family.
messages: Nucleus membrane
messages: Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance.
messages: nuclear pore complex

219594:BEST3
gene id: 219594:BEST3
uniprot id: A0A6J3EN91
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bestrophin family.
messages: Cell membrane
messages: Forms chloride channels.
messages: Membrane

219594:EI24
gene id: 219594:EI24
uniprot id: A0A6J3E7Q4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EI24 family.
messages: Membrane

219594:SLC35A4
gene id: 219594:SLC35A4
uniprot id: A0A6J3DTY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide-sugar transporter family. SLC35A subfamily.
messages: Membrane

219594:CDC42EP3
gene id: 219594:CDC42EP3
uniprot id: A0A6J3CRG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BORG/CEP family.
messages: Endomembrane system

219594:SLC25A51
gene id: 219594:SLC25A51
uniprot id: A0A6J3EET3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

219594:UBE2D1
gene id: 219594:UBE2D1
uniprot id: A0A6J3D748
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

219594:PNRC1
gene id: 219594:PNRC1
uniprot id: A0A6J3CUL3
names: Subcellular Location Annotation
messages: Nucleus

219594:UBA5
gene id: 219594:UBA5
uniprot id: A0A6J3CK05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ubiquitin-activating E1 family. UBA5 subfamily.
messages: Golgi apparatus

219594:RFTN2
gene id: 219594:RFTN2
uniprot id: A0A6J3D4W4
uniprot id: A0A6J3DA91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the raftlin family.
messages: Cell membrane
messages: Membrane

219594:SGMS2
gene id: 219594:SGMS2
uniprot id: A0A6J3D046
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sphingomyelin synthase family.
messages: Membrane

219594:LOC116497611
gene id: 219594:LOC116497611
uniprot id: A0A6J3E190
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DAN family.
messages: Secreted

219594:FGF20
gene id: 219594:FGF20
uniprot id: A0A6J3CYJ7
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

219594:LOC116499880
gene id: 219594:LOC116499880
uniprot id: A0A6J3EFC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:NXN
gene id: 219594:NXN
uniprot id: A0A6J3E017
names: Similarity
messages: Belongs to the nucleoredoxin family.

219594:LOC116498872
gene id: 219594:LOC116498872
uniprot id: A0A6J3E7X3
names: Similarity
messages: Belongs to the peptidase A1 family.

219594:TSR3
gene id: 219594:TSR3
uniprot id: A0A6J3DPF8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Aminocarboxypropyltransferase that catalyzes the aminocarboxypropyl transfer on pseudouridine at position 1248 (Psi1248) in 18S rRNA. It constitutes the last step in biosynthesis of the hypermodified N1-methyl-N3-(3-amino-3-carboxypropyl) pseudouridine (m1acp3-Psi) conserved in eukaryotic 18S rRNA.
messages: Belongs to the TDD superfamily. TSR3 family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:LOC116497367
gene id: 219594:LOC116497367
uniprot id: A0A6J3E4A0
names: Similarity
messages: Belongs to the Schlafen family. Subgroup III subfamily.

219594:TRPM3
gene id: 219594:TRPM3
uniprot id: A0A6J3EGZ6
names: Subcellular Location Annotation
messages: Membrane

219594:MDH2
gene id: 219594:MDH2
uniprot id: A0A6J3E002
names: Similarity
names: Subunit
messages: Belongs to the LDH/MDH superfamily. MDH type 1 family.
messages: Homodimer.

219594:LOC116498392
gene id: 219594:LOC116498392
uniprot id: A0A6J3E9H3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the COA3 family.
messages: Component of 250-400 kDa complexes called cytochrome oxidase assembly intermediates or COA complexes.
messages: Core component of the MITRAC (mitochondrial translation regulation assembly intermediate of cytochrome c oxidase complex) complex, that regulates cytochrome c oxidase assembly. MITRAC complexes regulate both translation of mitochondrial encoded components and assembly of nuclear-encoded components imported in mitochondrion. Required for efficient translation of MT-CO1 and mitochondrial respiratory chain complex IV assembly.
messages: Membrane
messages: Required for assembly of cytochrome c oxidase (complex IV).

219594:LOC116498512
gene id: 219594:LOC116498512
uniprot id: A0A6J3E6C7
names: Similarity
names: Subunit
messages: Belongs to the avian keratin family.
messages: The avian keratins (F-ker, S-ker, C-ker and B-ker) are a complex mixture of very similar polypeptides.

219594:CUTC
gene id: 219594:CUTC
uniprot id: A0A6J3D716
uniprot id: A0A6J3DD00
names: Similarity
messages: Belongs to the CutC family.

219594:TCP11L1
gene id: 219594:TCP11L1
uniprot id: A0A6J3D1T5
names: Similarity
messages: Belongs to the TCP11 family.

219594:LOC116498555
gene id: 219594:LOC116498555
uniprot id: A0A6J3E9J4
names: Subcellular Location Annotation
messages: Membrane

219594:EAF2
gene id: 219594:EAF2
uniprot id: A0A6J3D453
names: Similarity
messages: Belongs to the EAF family.

219594:KIFBP
gene id: 219594:KIFBP
uniprot id: A0A6J3D9W4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KIF-binding protein family.
messages: cytoskeleton

219594:RAB32
gene id: 219594:RAB32
uniprot id: A0A6J3CMZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Membrane
messages: The small GTPases Rab are key regulators in vesicle trafficking.

219594:HYLS1
gene id: 219594:HYLS1
uniprot id: A0A6J3E2W5
uniprot id: A0A6J3E7V3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HYLS1 family.
messages: centriole
messages: cilium

219594:EGR1
gene id: 219594:EGR1
uniprot id: A0A6J3DN88
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EGR C2H2-type zinc-finger protein family.
messages: Nucleus
messages: Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death.

219594:IPO11
gene id: 219594:IPO11
uniprot id: A0A6J3EI86
names: Subcellular Location Annotation
messages: Cytoplasm

219594:TNFSF10
gene id: 219594:TNFSF10
uniprot id: A0A6J3DDA1
uniprot id: A0A6J3DH70
uniprot id: A0A6J3DIU1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tumor necrosis factor family.
messages: Membrane
messages: Secreted

219594:ATR
gene id: 219594:ATR
uniprot id: A0A6J3DFB8
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. ATM subfamily.

219594:AMPD3
gene id: 219594:AMPD3
uniprot id: A0A6J3D154
uniprot id: A0A6J3D3M7
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.

219594:SLC28A3
gene id: 219594:SLC28A3
uniprot id: A0A6J3EJW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.
messages: Membrane

219594:BCL9L
gene id: 219594:BCL9L
uniprot id: A0A6J3E980
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BCL9 family.
messages: Nucleus

219594:PLCG2
gene id: 219594:PLCG2
uniprot id: A0A6J3DMF2
names: Function
messages: Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.

219594:ATP8A2
gene id: 219594:ATP8A2
uniprot id: A0A6J3EJI0
uniprot id: A0A6J3EKU6
uniprot id: A0A6J3EPT0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

219594:SCUBE1
gene id: 219594:SCUBE1
uniprot id: A0A6J3EB28
uniprot id: A0A6J3EB39
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

219594:LOC116498302
gene id: 219594:LOC116498302
uniprot id: A0A6J3E482
names: Similarity
names: Subunit
messages: Belongs to the avian keratin family.
messages: The avian keratins (F-ker, S-ker, C-ker and B-ker) are a complex mixture of very similar polypeptides.

219594:VIP
gene id: 219594:VIP
uniprot id: A0A6J3CXK0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glucagon family.
messages: Secreted
messages: VIP causes vasodilation, lowers arterial blood pressure, stimulates myocardial contractility, increases glycogenolysis and relaxes the smooth muscle of trachea, stomach and gall bladder.

219594:SAG
gene id: 219594:SAG
uniprot id: A0A6J3DIG1
names: Similarity
messages: Belongs to the arrestin family.

219594:STK32A
gene id: 219594:STK32A
uniprot id: A0A6J3DT53
names: Similarity
messages: Belongs to the protein kinase superfamily.

219594:INKA1
gene id: 219594:INKA1
uniprot id: A0A6J3DKQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the INKA family.
messages: Nucleus

219594:SAT1
gene id: 219594:SAT1
uniprot id: A0A6J3EJJ3
names: Similarity
names: Subunit
messages: Belongs to the acetyltransferase family.
messages: Homodimer.

219594:CPB1
gene id: 219594:CPB1
uniprot id: A0A6J3DJ95
names: Similarity
messages: Belongs to the peptidase M14 family.

219594:LOC116500606
gene id: 219594:LOC116500606
uniprot id: A0A6J3ED20
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

219594:LOC116485688
gene id: 219594:LOC116485688
uniprot id: A0A6J3CG75
names: Similarity
names: Subunit
messages: Belongs to the avian keratin family.
messages: The avian keratins (F-ker, S-ker, C-ker and B-ker) are a complex mixture of very similar polypeptides.

219594:SYNE3
gene id: 219594:SYNE3
uniprot id: A0A6J3D1F0
uniprot id: A0A6J3D3S8
uniprot id: A0A6J3D449
names: Similarity
messages: Belongs to the nesprin family.

219594:SYF2
gene id: 219594:SYF2
uniprot id: A0A6J3E8E9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SYF2 family.
messages: Involved in pre-mRNA splicing.
messages: May be part of a spliceosome complex.
messages: Nucleus

219594:MC5R
gene id: 219594:MC5R
uniprot id: A0A6J3CK50
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. This receptor is a possible mediator of the immunomodulation properties of melanocortins.

219594:TNFSF15
gene id: 219594:TNFSF15
uniprot id: A0A6J3E004
names: Similarity
messages: Belongs to the tumor necrosis factor family.

219594:EPN3
gene id: 219594:EPN3
uniprot id: A0A6J3E153
uniprot id: A0A6J3E1Y1
uniprot id: A0A6J3E337
names: Similarity
messages: Belongs to the epsin family.

219594:PIGZ
gene id: 219594:PIGZ
uniprot id: A0A6J3DEZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 22 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

219594:SLITRK6
gene id: 219594:SLITRK6
uniprot id: A0A6J3EQ61
names: Similarity
messages: Belongs to the SLITRK family.

219594:CRYGN
gene id: 219594:CRYGN
uniprot id: A0A6J3CMH8
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

219594:EVPL
gene id: 219594:EVPL
uniprot id: A0A6J3E1C2
names: Subcellular Location Annotation
messages: cytoskeleton

219594:SMC1B
gene id: 219594:SMC1B
uniprot id: A0A6J3CYF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMC family. SMC1 subfamily.
messages: Chromosome
messages: Nucleus

219594:USP14
gene id: 219594:USP14
uniprot id: A0A6J3CHZ5
names: Similarity
names: Subunit
messages: Belongs to the peptidase C19 family. USP14/UBP6 subfamily.
messages: Homodimer (Potential). Associates with the 26S proteasome. Interacts with FANCC, CXCR4 and ERN1. Interacts with TRIM14; this interaction recruits USP14 to cleave ubiquitin chains of CGAS.

219594:ISM1
gene id: 219594:ISM1
uniprot id: A0A6J3CS27
names: Similarity
messages: Belongs to the isthmin family.

219594:FGFR3
gene id: 219594:FGFR3
uniprot id: A0A6J3CTF3
uniprot id: A0A6J3CYI6
uniprot id: A0A6J3CZK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. Fibroblast growth factor receptor subfamily.
messages: Membrane

219594:CNPY1
gene id: 219594:CNPY1
uniprot id: A0A6J3CJW4
names: Similarity
messages: Belongs to the canopy family.

219594:LOC116491083
gene id: 219594:LOC116491083
uniprot id: A0A6J3D832
uniprot id: A0A6J3DAS2
names: Subcellular Location Annotation
messages: Endoplasmic reticulum
messages: Mitochondrion
messages: cytosol

219594:GRM4
gene id: 219594:GRM4
uniprot id: A0A6J3EAN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 3 family.
messages: Cell membrane
messages: Membrane

219594:FAS
gene id: 219594:FAS
uniprot id: A0A6J3DE07
uniprot id: A0A6J3DEA9
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane raft

219594:UBE2D3
gene id: 219594:UBE2D3
uniprot id: A0A6J3CTP3
uniprot id: A0A6J3CZT1
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

219594:VSIG1
gene id: 219594:VSIG1
uniprot id: A0A6J3DR45
names: Subcellular Location Annotation
messages: Membrane

219594:LOC116488612
gene id: 219594:LOC116488612
uniprot id: A0A6J3CVA5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

219594:PFDN2
gene id: 219594:PFDN2
uniprot id: A0A6J3EE93
names: Function
names: Similarity
messages: Belongs to the prefoldin subunit beta family.
messages: Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins.

219594:WNT7B
gene id: 219594:WNT7B
uniprot id: A0A6J3DWP2
uniprot id: A0A6J3E2P8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

219594:EBF1
gene id: 219594:EBF1
uniprot id: A0A6J3DMQ8
uniprot id: A0A6J3DQ16
uniprot id: A0A6J3DQ21
uniprot id: A0A6J3DS24
uniprot id: A0A6J3DS31
uniprot id: A0A6J3DSV7
uniprot id: A0A6J3DTW5
uniprot id: A0A6J3DTW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COE family.
messages: Nucleus

219594:GMNN
gene id: 219594:GMNN
uniprot id: A0A6J3CFU9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the geminin family.
messages: Nucleus

219594:KDM4B
gene id: 219594:KDM4B
uniprot id: A0A6J3E712
uniprot id: A0A6J3E8J2
uniprot id: A0A6J3EBK8
names: Similarity
messages: Belongs to the JHDM3 histone demethylase family.

219594:FAM171B
gene id: 219594:FAM171B
uniprot id: A0A6J3D565
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM171 family.
messages: Membrane

219594:KYNU
gene id: 219594:KYNU
uniprot id: A0A6J3D6I4
uniprot id: A0A6J3D718
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the kynureninase family.
messages: Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:ENSA
gene id: 219594:ENSA
uniprot id: A0A6J3EA05
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endosulfine family.
messages: Cytoplasm
messages: Protein phosphatase inhibitor that specifically inhibits protein phosphatase 2A (PP2A) during mitosis.

219594:SHC1
gene id: 219594:SHC1
uniprot id: A0A6J3E9W3
uniprot id: A0A6J3EBA6
uniprot id: A0A6J3EBB0
uniprot id: A0A6J3EEL3
uniprot id: A0A6J3EEL8
uniprot id: A0A6J3EGM1
names: Subcellular Location Annotation
messages: Cytoplasm

219594:LRP6
gene id: 219594:LRP6
uniprot id: A0A6J3DAK2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LDLR family.
messages: Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes.
messages: Homodimer; disulfide-linked. Forms phosphorylated oligomer aggregates on Wnt-signaling.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:RFC4
gene id: 219594:RFC4
uniprot id: A0A6J3DJV5
names: Similarity
messages: Belongs to the activator 1 small subunits family.

219594:SLC25A20
gene id: 219594:SLC25A20
uniprot id: A0A6J3DLE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

219594:PIGP
gene id: 219594:PIGP
uniprot id: A0A6J3DNJ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGP family.
messages: Membrane
messages: Part of the complex catalyzing the transfer of N-acetylglucosamine from UDP-N-acetylglucosamine to phosphatidylinositol, the first step of GPI biosynthesis.

219594:PLIN2
gene id: 219594:PLIN2
uniprot id: A0A6J3EEB6
uniprot id: A0A6J3EJD1
names: Similarity
messages: Belongs to the perilipin family.

219594:LOC116501414
gene id: 219594:LOC116501414
uniprot id: A0A6J3ELR8
uniprot id: A0A6J3ELV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vasculin family.
messages: Nucleus

219594:C8G
gene id: 219594:C8G
uniprot id: A0A6J3E430
names: Subcellular Location Annotation
messages: Secreted

219594:LOC116498186
gene id: 219594:LOC116498186
uniprot id: A0A6J3E5C8
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

219594:LOC116486432
gene id: 219594:LOC116486432
uniprot id: A0A6J3CHT2
uniprot id: A0A6J3CMF9
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: basement membrane

219594:LOC116486477
gene id: 219594:LOC116486477
uniprot id: A0A6J3CP54
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alpha-carbonic anhydrase family.
messages: Cytoplasm
messages: Reversible hydration of carbon dioxide.

219594:PDCL
gene id: 219594:PDCL
uniprot id: A0A6J3E3M8
names: Similarity
messages: Belongs to the phosducin family.

219594:TRNAU1AP
gene id: 219594:TRNAU1AP
uniprot id: A0A6J3E3J2
uniprot id: A0A6J3E8I5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM TRSPAP family.
messages: Cytoplasm
messages: Nucleus

219594:LOC116501278
gene id: 219594:LOC116501278
uniprot id: A0A6J3EHJ6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:TMEM98
gene id: 219594:TMEM98
uniprot id: A0A6J3E4X2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM98 family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: extracellular exosome

219594:LIPG
gene id: 219594:LIPG
uniprot id: A0A6J3EEP4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AB hydrolase superfamily. Lipase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

219594:KANSL2
gene id: 219594:KANSL2
uniprot id: A0A6J3EAG1
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: As part of the NSL complex it is involved in acetylation of nucleosomal histone H4 on several lysine residues and therefore may be involved in the regulation of transcription.
messages: Component of the NSL complex at least composed of MOF/KAT8, KANSL1, KANSL2, KANSL3, MCRS1, PHF20, OGT1/OGT, WDR5 and HCFC1.
messages: Nucleus

219594:TENT5A
gene id: 219594:TENT5A
uniprot id: A0A6J3CQM8
names: Similarity
messages: Belongs to the TENT family.

219594:AUH
gene id: 219594:AUH
uniprot id: A0A6J3EKS1
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

219594:MCOLN2
gene id: 219594:MCOLN2
uniprot id: A0A6J3DDU5
names: Subcellular Location Annotation
messages: Endosome membrane
messages: Membrane

219594:WASF1
gene id: 219594:WASF1
uniprot id: A0A6J3CW82
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SCAR/WAVE family.
messages: Binds actin and the Arp2/3 complex.
messages: Downstream effector molecule involved in the transmission of signals from tyrosine kinase receptors and small GTPases to the actin cytoskeleton. Promotes formation of actin filaments. Part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex.
messages: cytoskeleton

219594:ACTA2
gene id: 219594:ACTA2
uniprot id: A0A6J3D7B9
names: Similarity
messages: Belongs to the actin family.

219594:PRKCI
gene id: 219594:PRKCI
uniprot id: A0A6J3DEK5
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.

219594:TUSC3
gene id: 219594:TUSC3
uniprot id: A0A6J3CSP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OST3/OST6 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

219594:P2RX3
gene id: 219594:P2RX3
uniprot id: A0A6J3D4Z8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the P2X receptor family.
messages: Functional P2XRs are organized as homomeric and heteromeric trimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Receptor for ATP that acts as a ligand-gated ion channel.

219594:SRRD
gene id: 219594:SRRD
uniprot id: A0A6J3DW41
names: Similarity
messages: Belongs to the SRR1 family.

219594:ANAPC16
gene id: 219594:ANAPC16
uniprot id: A0A6J3D9M1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the APC16 family.
messages: Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.
messages: Cytoplasm
messages: Nucleus
messages: kinetochore

219594:AHCY
gene id: 219594:AHCY
uniprot id: A0A6J3DU10
names: Cofactor
names: Similarity
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.

219594:TCP11
gene id: 219594:TCP11
uniprot id: A0A6J3EC44
names: Similarity
messages: Belongs to the TCP11 family.

219594:RPL35A
gene id: 219594:RPL35A
uniprot id: A0A6J3DD18
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL33 family.

219594:EARS2
gene id: 219594:EARS2
uniprot id: A0A6J3DUJ6
names: Function
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).

219594:GPR12
gene id: 219594:GPR12
uniprot id: A0A6J3EJQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:PCBP4
gene id: 219594:PCBP4
uniprot id: A0A6J3DF81
names: Subcellular Location Annotation
messages: Cytoplasm

219594:LEAP2
gene id: 219594:LEAP2
uniprot id: A0A6J3DRF8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LEAP2 family.
messages: Has an antimicrobial activity.
messages: Secreted

219594:LOC116490905
gene id: 219594:LOC116490905
uniprot id: A0A6J3D7J3
names: Similarity
messages: Belongs to the cytochrome P450 family.

219594:COQ7
gene id: 219594:COQ7
uniprot id: A0A6J3DT44
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the COQ7 family.
messages: Binds 2 iron ions per subunit.
messages: Catalyzes the hydroxylation of 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) during ubiquinone biosynthesis. Has also a structural role in the COQ enzyme complex, stabilizing other COQ polypeptides. Involved in lifespan determination in a ubiquinone-independent manner.
messages: Component of a multi-subunit COQ enzyme complex, composed of at least COQ3, COQ4, COQ5, COQ6, COQ7 and COQ9. Interacts with ADCK4 and COQ6. Interacts with COQ9.
messages: Mitochondrion inner membrane

219594:GUCY1A2
gene id: 219594:GUCY1A2
uniprot id: A0A6J3EFX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Cytoplasm

219594:CRHBP
gene id: 219594:CRHBP
uniprot id: A0A6J3EK34
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CRF-binding protein family.
messages: Binds CRF and inactivates it. May prevent inappropriate pituitary-adrenal stimulation in pregnancy.
messages: Secreted

219594:AP3D1
gene id: 219594:AP3D1
uniprot id: A0A6J3EBD1
names: Similarity
messages: Belongs to the adaptor complexes large subunit family.

219594:INA
gene id: 219594:INA
uniprot id: A0A6J3DAU9
names: Similarity
messages: Belongs to the intermediate filament family.

219594:DNAH1
gene id: 219594:DNAH1
uniprot id: A0A6J3DEV8
names: Similarity
messages: Belongs to the dynein heavy chain family.

219594:ADAM22
gene id: 219594:ADAM22
uniprot id: A0A6J3CEU7
uniprot id: A0A6J3CGH4
uniprot id: A0A6J3CGH8
uniprot id: A0A6J3CHG3
uniprot id: A0A6J3CHG8
uniprot id: A0A6J3CJC5
uniprot id: A0A6J3CJD1
uniprot id: A0A6J3CL25
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:HEXA
gene id: 219594:HEXA
uniprot id: A0A6J3DJZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 20 family.
messages: Lysosome

219594:STON2
gene id: 219594:STON2
uniprot id: A0A6J3D4R2
uniprot id: A0A6J3D5P7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Stoned B family.
messages: Cytoplasm

219594:LOC116486747
gene id: 219594:LOC116486747
uniprot id: A0A6J3CQB9
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

219594:PCNX2
gene id: 219594:PCNX2
uniprot id: A0A6J3CKR3
uniprot id: A0A6J3CRQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pecanex family.
messages: Membrane

219594:CACNA1H
gene id: 219594:CACNA1H
uniprot id: A0A6J3DPM3
uniprot id: A0A6J3DTY0
names: Subcellular Location Annotation
messages: Membrane

219594:LOC116489887
gene id: 219594:LOC116489887
uniprot id: A0A6J3CZP0
names: Domain
names: Subcellular Location Annotation
messages: The N-terminal C2 domain associates with lipid membranes upon calcium binding.
messages: cytosol

219594:LAMA4
gene id: 219594:LAMA4
uniprot id: A0A6J3CSS1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:PATJ
gene id: 219594:PATJ
uniprot id: A0A6J3DEP1
names: Subcellular Location Annotation
messages: tight junction

219594:CDK5R1
gene id: 219594:CDK5R1
uniprot id: A0A6J3EBD9
names: Similarity
messages: Belongs to the cyclin-dependent kinase 5 activator family.

219594:AMDHD1
gene id: 219594:AMDHD1
uniprot id: A0A6J3E4R4
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. HutI family.

219594:TSEN2
gene id: 219594:TSEN2
uniprot id: A0A6J3DL98
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA-intron endonuclease family.
messages: Constitutes one of the two catalytic subunit of the tRNA-splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3'-cyclic phosphate and 5'-OH termini. There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structural features of the tRNA body.
messages: Nucleus

219594:SCG3
gene id: 219594:SCG3
uniprot id: A0A6J3DG26
uniprot id: A0A6J3DK25
names: Subcellular Location Annotation
messages: Membrane
messages: Secreted
messages: secretory vesicle membrane

219594:ANXA10
gene id: 219594:ANXA10
uniprot id: A0A6J3CY18
names: Similarity
messages: Belongs to the annexin family.

219594:CRH
gene id: 219594:CRH
uniprot id: A0A6J3CK35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sauvagine/corticotropin-releasing factor/urotensin I family.
messages: Secreted

219594:LOC116488494
gene id: 219594:LOC116488494
uniprot id: A0A6J3CYH1
names: Similarity
messages: Belongs to the aldo/keto reductase family.

219594:LOC116494380
gene id: 219594:LOC116494380
uniprot id: A0A6J3DRA9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FIP1 family.
messages: Nucleus

219594:ERCC4
gene id: 219594:ERCC4
uniprot id: A0A6J3DWL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XPF family.
messages: Nucleus

219594:MED28
gene id: 219594:MED28
uniprot id: A0A6J3CWA9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mediator complex subunit 28 family.
messages: Nucleus

219594:EPB41
gene id: 219594:EPB41
uniprot id: A0A6J3E3C6
uniprot id: A0A6J3E3C9
uniprot id: A0A6J3E3D4
uniprot id: A0A6J3E3D9
uniprot id: A0A6J3E3E4
uniprot id: A0A6J3E4R5
uniprot id: A0A6J3E4S0
uniprot id: A0A6J3E4S6
uniprot id: A0A6J3E4T0
uniprot id: A0A6J3E4U2
uniprot id: A0A6J3E7N7
uniprot id: A0A6J3E7P2
uniprot id: A0A6J3E7P5
uniprot id: A0A6J3E7Q0
uniprot id: A0A6J3E7Q5
uniprot id: A0A6J3E8B0
uniprot id: A0A6J3E8B5
uniprot id: A0A6J3E8C0
uniprot id: A0A6J3E8C4
uniprot id: A0A6J3E8C9
uniprot id: A0A6J3E8D2
uniprot id: A0A6J3E9Q6
uniprot id: A0A6J3E9R1
uniprot id: A0A6J3E9R5
uniprot id: A0A6J3E9S1
uniprot id: A0A6J3E9S6
uniprot id: A0A6J3E9T2
names: Subcellular Location Annotation
messages: Nucleus
messages: cell cortex

219594:UXS1
gene id: 219594:UXS1
uniprot id: A0A6J3CF02
uniprot id: A0A6J3CHW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily.
messages: Golgi stack membrane
messages: Membrane

219594:LOC116487537
gene id: 219594:LOC116487537
uniprot id: A0A6J3CPX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. Very large inducible GTPase (VLIG) family.
messages: Nucleus

219594:PGAP6
gene id: 219594:PGAP6
uniprot id: A0A6J3DQA8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM8 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

219594:AFG1L
gene id: 219594:AFG1L
uniprot id: A0A6J3CPC8
names: Similarity
messages: Belongs to the AFG1 ATPase family.

219594:MED14
gene id: 219594:MED14
uniprot id: A0A6J3DBD9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 14 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

219594:DUSP10
gene id: 219594:DUSP10
uniprot id: A0A6J3CP11
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.

219594:HMX3
gene id: 219594:HMX3
uniprot id: A0A6J3D8C1
names: Subcellular Location Annotation
messages: Nucleus

219594:MBD4
gene id: 219594:MBD4
uniprot id: A0A6J3DKV5
names: Subcellular Location Annotation
messages: Nucleus

219594:BTG1
gene id: 219594:BTG1
uniprot id: A0A6J3E8J7
names: Function
names: Similarity
messages: Anti-proliferative protein.
messages: Belongs to the BTG family.

219594:B3GALT2
gene id: 219594:B3GALT2
uniprot id: A0A6J3DEI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

219594:PUS1
gene id: 219594:PUS1
uniprot id: A0A6J3DYT3
names: Similarity
messages: Belongs to the tRNA pseudouridine synthase TruA family.

219594:LOC116500109
gene id: 219594:LOC116500109
uniprot id: A0A6J3EB51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:MAB21L3
gene id: 219594:MAB21L3
uniprot id: A0A6J3EIM3
names: Similarity
messages: Belongs to the mab-21 family.

219594:LOC116497231
gene id: 219594:LOC116497231
uniprot id: A0A6J3E3S0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat SEC13 family.
messages: Lysosome membrane
messages: nuclear pore complex

219594:ATP5F1D
gene id: 219594:ATP5F1D
uniprot id: A0A6J3E9G5
names: Similarity
messages: Belongs to the ATPase epsilon chain family.

219594:CRPPA
gene id: 219594:CRPPA
uniprot id: A0A6J3CEP1
uniprot id: A0A6J3CFP1
uniprot id: A0A6J3CJA8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Homodimer.
messages: cytosol

219594:LOC116489648
gene id: 219594:LOC116489648
uniprot id: A0A6J3CYD3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

219594:LOC116492440
gene id: 219594:LOC116492440
uniprot id: A0A6J3DC92
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

219594:DUSP6
gene id: 219594:DUSP6
uniprot id: A0A6J3EQD2
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.

219594:LOC116494053
gene id: 219594:LOC116494053
uniprot id: A0A6J3DQP8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

219594:LOC116491877
gene id: 219594:LOC116491877
uniprot id: A0A6J3DC98
names: Similarity
messages: Belongs to the amidase family.

219594:POMGNT2
gene id: 219594:POMGNT2
uniprot id: A0A6J3CF58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 61 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

219594:SLC25A32
gene id: 219594:SLC25A32
uniprot id: A0A6J3CMZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

219594:IDI1
gene id: 219594:IDI1
uniprot id: A0A6J3CIK6
names: Function
names: Similarity
messages: Belongs to the IPP isomerase type 1 family.
messages: Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).

219594:LOC116500391
gene id: 219594:LOC116500391
uniprot id: A0A6J3EGT5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alpha/beta interferon family.
messages: Has antiviral activities.
messages: Secreted

219594:AOC1
gene id: 219594:AOC1
uniprot id: A0A6J3CLW5
names: Cofactor
names: PTM
names: Similarity
messages: Belongs to the copper/topaquinone oxidase family.
messages: Contains 1 topaquinone per subunit.
messages: Topaquinone (TPQ) is generated by copper-dependent autoxidation of a specific tyrosyl residue.

219594:TNMD
gene id: 219594:TNMD
uniprot id: A0A6J3DQ09
names: Similarity
messages: Belongs to the chondromodulin-1 family.

219594:LOC116488502
gene id: 219594:LOC116488502
uniprot id: A0A6J3CSC2
uniprot id: A0A6J3CXE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 1 family. NDST subfamily.
messages: Membrane

219594:UBR4
gene id: 219594:UBR4
uniprot id: A0A6J3E147
names: Similarity
messages: Belongs to the UBR4 family.

219594:LIX1
gene id: 219594:LIX1
uniprot id: A0A6J3EF27
names: Similarity
messages: Belongs to the LIX1 family.

219594:LOC116499714
gene id: 219594:LOC116499714
uniprot id: A0A6J3EB67
names: Similarity
messages: Belongs to the protein kinase superfamily.

219594:RHAG
gene id: 219594:RHAG
uniprot id: A0A6J3CMY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonium transporter (TC 2.A.49) family. Rh subfamily.
messages: Membrane

219594:LOC116501455
gene id: 219594:LOC116501455
uniprot id: A0A6J3ELZ4
names: Subcellular Location Annotation
messages: Nucleus

219594:CHST9
gene id: 219594:CHST9
uniprot id: A0A6J3CJH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 2 family.
messages: Golgi apparatus membrane
messages: Membrane

219594:PSMB1
gene id: 219594:PSMB1
uniprot id: A0A6J3CTD3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome complex.
messages: Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
messages: Cytoplasm
messages: Nucleus

219594:STRIP1
gene id: 219594:STRIP1
uniprot id: A0A6J3E7R9
uniprot id: A0A6J3EAS0
names: Similarity
messages: Belongs to the STRIP family.

219594:FLT1
gene id: 219594:FLT1
uniprot id: A0A6J3DFW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
messages: Membrane

219594:NR6A1
gene id: 219594:NR6A1
uniprot id: A0A6J3E2I7
uniprot id: A0A6J3E3C4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

219594:OLAH
gene id: 219594:OLAH
uniprot id: A0A6J3CJ11
names: Similarity
messages: Belongs to the thioesterase family.

219594:VDAC1
gene id: 219594:VDAC1
uniprot id: A0A6J3DU02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic mitochondrial porin family.
messages: Cell membrane
messages: Membrane
messages: Membrane raft

219594:LOC116489199
gene id: 219594:LOC116489199
uniprot id: A0A6J3D260
names: Similarity
messages: Belongs to the vasopressin/oxytocin family.

219594:MPP7
gene id: 219594:MPP7
uniprot id: A0A6J3CEX6
uniprot id: A0A6J3CGK0
uniprot id: A0A6J3CHJ2
uniprot id: A0A6J3CL60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAGUK family.
messages: adherens junction
messages: tight junction

219594:VSX2
gene id: 219594:VSX2
uniprot id: A0A6J3D1F7
names: Subcellular Location Annotation
messages: Nucleus

219594:MMD
gene id: 219594:MMD
uniprot id: A0A6J3E150
uniprot id: A0A6J3E293
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

219594:PARP1
gene id: 219594:PARP1
uniprot id: A0A6J3CQ92
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ARTD/PARP family.
messages: Chromosome
messages: Nucleus
messages: Poly-ADP-ribosyltransferase that mediates poly-ADP-ribosylation of proteins and plays a key role in DNA repair.

219594:LOC116489514
gene id: 219594:LOC116489514
uniprot id: A0A6J3D058
names: Similarity
messages: Belongs to the peptidase A1 family.

219594:TECRL
gene id: 219594:TECRL
uniprot id: A0A6J3D2J2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the steroid 5-alpha reductase family.
messages: Membrane

219594:LOC116492484
gene id: 219594:LOC116492484
uniprot id: A0A6J3DF32
names: Similarity
messages: Belongs to the galactose-3-O-sulfotransferase family.

219594:STAB2
gene id: 219594:STAB2
uniprot id: A0A6J3CKF4
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

219594:LOC116500176
gene id: 219594:LOC116500176
uniprot id: A0A6J3EHZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. BTN/MOG family.
messages: Membrane

219594:NOL12
gene id: 219594:NOL12
uniprot id: A0A6J3DFN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRP17 family.
messages: nucleolus

219594:MAPRE2
gene id: 219594:MAPRE2
uniprot id: A0A6J3CFC3
uniprot id: A0A6J3CI78
uniprot id: A0A6J3CJX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAPRE family.
messages: cytoskeleton

219594:BMS1
gene id: 219594:BMS1
uniprot id: A0A6J3D9Q1
names: Subcellular Location Annotation
messages: nucleolus

219594:ERAP1
gene id: 219594:ERAP1
uniprot id: A0A6J3EIX3
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.

219594:AGPS
gene id: 219594:AGPS
uniprot id: A0A6J3D8Y2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FAD-binding oxidoreductase/transferase type 4 family.
messages: Catalyzes the exchange of an acyl for a long-chain alkyl group and the formation of the ether bond in the biosynthesis of ether phospholipids.
messages: Homodimer.
messages: Peroxisome

219594:SERINC1
gene id: 219594:SERINC1
uniprot id: A0A6J3CT28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TDE1 family.
messages: Membrane

219594:BZW1
gene id: 219594:BZW1
uniprot id: A0A6J3D547
uniprot id: A0A6J3D7B7
names: Similarity
messages: Belongs to the BZW family.

219594:GPAM
gene id: 219594:GPAM
uniprot id: A0A6J3D891
uniprot id: A0A6J3DAZ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPAT/DAPAT family.
messages: Esterifies acyl-group from acyl-ACP to the sn-1 position of glycerol-3-phosphate, an essential step in glycerolipids biosynthesis such as triglycerides, phosphatidic acids and lysophosphatidic acids.
messages: Mitochondrion outer membrane

219594:PIK3CG
gene id: 219594:PIK3CG
uniprot id: A0A6J3E5Z8
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.

219594:MRPL3
gene id: 219594:MRPL3
uniprot id: A0A6J3CEU0
names: Similarity
messages: Belongs to the universal ribosomal protein uL3 family.

219594:TYSND1
gene id: 219594:TYSND1
uniprot id: A0A6J3D971
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1B family.
messages: Peroxisomal protease that mediates both the removal of the leader peptide from proteins containing a PTS2 target sequence and processes several PTS1-containing proteins. Catalyzes the processing of PTS1-proteins involved in the peroxisomal beta-oxidation of fatty acids.
messages: Peroxisome
messages: The full-lengh TYSND1 is the active the proteolytic processing of PTS1- and PTS2-proteins and in self-cleavage, and intermolecular self-cleavage of TYSND1 down-regulates its protease activity.

219594:LOC116501277
gene id: 219594:LOC116501277
uniprot id: A0A6J3EMR8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:ATP8
gene id: 219594:ATP8
uniprot id: A0A068LE44
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase protein 8 family.
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel.
messages: Membrane
messages: Mitochondrion membrane

219594:LOC116499068
gene id: 219594:LOC116499068
uniprot id: A0A6J3EBW8
names: Subcellular Location Annotation
messages: Membrane

219594:MFAP1
gene id: 219594:MFAP1
uniprot id: A0A6J3DNR7
names: Function
names: Similarity
messages: Belongs to the MFAP1 family.
messages: Involved in pre-mRNA splicing as a component of the spliceosome.

219594:LOC116495014
gene id: 219594:LOC116495014
uniprot id: A0A6J3DTU9
names: Similarity
messages: Belongs to the LECT2/MIM-1 family.

219594:ERO1A
gene id: 219594:ERO1A
uniprot id: A0A6J3D483
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EROs family.
messages: Endoplasmic reticulum membrane

219594:LOC116485714
gene id: 219594:LOC116485714
uniprot id: A0A6J3CGB6
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

219594:TRDN
gene id: 219594:TRDN
uniprot id: A0A6J3CTX0
names: Subcellular Location Annotation
messages: Membrane
messages: Sarcoplasmic reticulum membrane

219594:RAB4A
gene id: 219594:RAB4A
uniprot id: A0A6J3CNN7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Cell membrane
messages: Protein transport.

219594:PRKAB2
gene id: 219594:PRKAB2
uniprot id: A0A6J3D9U9
uniprot id: A0A6J3DDG5
names: Function
names: Similarity
messages: Belongs to the 5'-AMP-activated protein kinase beta subunit family.
messages: Non-catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton; probably by indirectly activating myosin. Beta non-catalytic subunit acts as a scaffold on which the AMPK complex assembles, via its C-terminus that bridges alpha (PRKAA1 or PRKAA2) and gamma subunits (PRKAG1, PRKAG2 or PRKAG3).

219594:ALCAM
gene id: 219594:ALCAM
uniprot id: A0A6J3CPP1
uniprot id: A0A6J3CVS7
names: Subcellular Location Annotation
messages: Cell membrane
messages: axon
messages: dendrite

219594:YIPF1
gene id: 219594:YIPF1
uniprot id: A0A6J3DB10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YIP1 family.
messages: Endosome membrane
messages: Late endosome membrane
messages: Membrane
messages: cis-Golgi network membrane
messages: trans-Golgi network membrane

219594:LOC116500111
gene id: 219594:LOC116500111
uniprot id: A0A6J3EHT7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:MTAP
gene id: 219594:MTAP
uniprot id: A0A6J3EK98
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
messages: Catalyzes the reversible phosphorylation of S-methyl-5'-thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.
messages: Cytoplasm
messages: Homotrimer.
messages: Nucleus

219594:LOC116500928
gene id: 219594:LOC116500928
uniprot id: A0A6J3EG24
names: Similarity
messages: Belongs to the calycin superfamily. Lipocalin family.

219594:PPP6R2
gene id: 219594:PPP6R2
uniprot id: A0A6J3CHZ2
uniprot id: A0A6J3CIZ0
names: Similarity
messages: Belongs to the SAPS family.

219594:ST8SIA5
gene id: 219594:ST8SIA5
uniprot id: A0A6J3EJD6
uniprot id: A0A6J3EL33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

219594:LHFPL5
gene id: 219594:LHFPL5
uniprot id: A0A6J3E613
names: Subcellular Location Annotation
messages: Membrane

219594:WSCD1
gene id: 219594:WSCD1
uniprot id: A0A6J3E154
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WSCD family.
messages: Membrane

219594:LOC116491999
gene id: 219594:LOC116491999
uniprot id: A0A6J3DFV1
names: Similarity
messages: Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.

219594:ALDH7A1
gene id: 219594:ALDH7A1
uniprot id: A0A6J3EEM4
names: Similarity
names: Subunit
messages: Belongs to the aldehyde dehydrogenase family.
messages: Homotetramer.

219594:KCNK5
gene id: 219594:KCNK5
uniprot id: A0A6J3CMP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

219594:WNT5B
gene id: 219594:WNT5B
uniprot id: A0A6J3ECR7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

219594:CALHM3
gene id: 219594:CALHM3
uniprot id: A0A6J3DC94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CALHM family.
messages: Membrane

219594:LOC116493988
gene id: 219594:LOC116493988
uniprot id: A0A6J3DQH0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

219594:SLITRK2
gene id: 219594:SLITRK2
uniprot id: A0A6J3DL60
names: Similarity
messages: Belongs to the SLITRK family.

219594:DCTN1
gene id: 219594:DCTN1
uniprot id: A0A6J3CSL7
uniprot id: A0A6J3CSM1
uniprot id: A0A6J3CUX6
uniprot id: A0A6J3CUY2
uniprot id: A0A6J3CVD2
uniprot id: A0A6J3CXQ0
uniprot id: A0A6J3CYS8
uniprot id: A0A6J3CYT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dynactin 150 kDa subunit family.
messages: Cytoplasm
messages: cell cortex
messages: cytoskeleton

219594:NEMP1
gene id: 219594:NEMP1
uniprot id: A0A6J3EF07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NEMP family.
messages: Nucleus inner membrane

219594:PSEN1
gene id: 219594:PSEN1
uniprot id: A0A6J3D3D5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase A22A family.
messages: Cytoplasmic granule
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Homodimer.
messages: Membrane
messages: Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors.
messages: Synapse
messages: The PAL motif is required for normal active site conformation.
messages: axon
messages: neuron projection

219594:LOC116498008
gene id: 219594:LOC116498008
uniprot id: A0A6J3E9H5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the argonaute family. Ago subfamily.
messages: P-body
messages: Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs.

219594:PDE1A
gene id: 219594:PDE1A
uniprot id: A0A6J3DB55
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family. PDE1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

219594:TSPAN18
gene id: 219594:TSPAN18
uniprot id: A0A6J3D0F2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

219594:SHROOM3
gene id: 219594:SHROOM3
uniprot id: A0A6J3CY35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the shroom family.
messages: cytoskeleton

219594:RPL23A
gene id: 219594:RPL23A
uniprot id: A0A6J3E5G9
names: Similarity
messages: Belongs to the universal ribosomal protein uL23 family.

219594:CACTIN
gene id: 219594:CACTIN
uniprot id: A0A6J3ECB3
names: Similarity
messages: Belongs to the CACTIN family.

219594:LOC116489534
gene id: 219594:LOC116489534
uniprot id: A0A6J3D3R5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:DDX1
gene id: 219594:DDX1
uniprot id: A0A6J3CT12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. DDX1 subfamily.
messages: Cytoplasmic granule

219594:LOC116485403
gene id: 219594:LOC116485403
uniprot id: A0A6J3CEU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Early endosome
messages: Endosome
messages: Membrane

219594:CLDN18
gene id: 219594:CLDN18
uniprot id: A0A6J3DH92
uniprot id: A0A6J3DJF3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

219594:GRK6
gene id: 219594:GRK6
uniprot id: A0A6J3DQ11
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.

219594:FAM168B
gene id: 219594:FAM168B
uniprot id: A0A6J3DIM7
names: Similarity
messages: Belongs to the FAM168 family.

219594:KIAA1191
gene id: 219594:KIAA1191
uniprot id: A0A6J3DSK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P33MONOX family.
messages: Cytoplasm

219594:SRP14
gene id: 219594:SRP14
uniprot id: A0A6J3D4Y5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SRP14 family.
messages: Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER). SRP9 together with SRP14 and the Alu portion of the SRP RNA, constitutes the elongation arrest domain of SRP. The complex of SRP9 and SRP14 is required for SRP RNA binding.
messages: Cytoplasm
messages: Heterodimer with SRP9; binds RNA as heterodimer. Component of a signal recognition particle (SRP) complex that consists of a 7SL RNA molecule of 300 nucleotides and six protein subunits: SRP72, SRP68, SRP54, SRP19, SRP14 and SRP9.

219594:LOC116500626
gene id: 219594:LOC116500626
uniprot id: A0A6J3EEI9
names: Cofactor
names: Function
names: Subunit
messages: Binds 1 zinc ion per subunit.
messages: Homotetramer.
messages: Involved in the regulation of homocysteine metabolism.

219594:OXR1
gene id: 219594:OXR1
uniprot id: A0A6J3CH49
uniprot id: A0A6J3CIN6
uniprot id: A0A6J3CJU0
names: Similarity
messages: Belongs to the OXR1 family.

219594:ELL2
gene id: 219594:ELL2
uniprot id: A0A6J3EGS1
uniprot id: A0A6J3EKG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELL/occludin family.
messages: Nucleus

219594:LFNG
gene id: 219594:LFNG
uniprot id: A0A6J3DUU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

219594:RIN3
gene id: 219594:RIN3
uniprot id: A0A6J3D233
names: Similarity
messages: Belongs to the RIN (Ras interaction/interference) family.

219594:CDK1
gene id: 219594:CDK1
uniprot id: A0A6J3DAW6
names: Similarity
messages: Belongs to the protein kinase superfamily.

219594:LOC116494580
gene id: 219594:LOC116494580
uniprot id: A0A6J3DR09
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

219594:APLP2
gene id: 219594:APLP2
uniprot id: A0A6J3E2S9
uniprot id: A0A6J3E2T4
uniprot id: A0A6J3E468
uniprot id: A0A6J3E741
uniprot id: A0A6J3E7S0
uniprot id: A0A6J3E964
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the APP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

219594:SDC2
gene id: 219594:SDC2
uniprot id: A0A6J3CKH6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the syndecan proteoglycan family.
messages: Cell surface proteoglycan.
messages: Membrane

219594:MAP2K6
gene id: 219594:MAP2K6
uniprot id: A0A6J3DVS6
names: Similarity
messages: Belongs to the protein kinase superfamily.

219594:LOC116486440
gene id: 219594:LOC116486440
uniprot id: A0A6J3CHU2
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c family.
messages: Binds 1 heme group per subunit.
messages: Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.
messages: Mitochondrion intermembrane space

219594:PDE7A
gene id: 219594:PDE7A
uniprot id: A0A6J3CH23
uniprot id: A0A6J3CJ05
uniprot id: A0A6J3CKP4
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

219594:LOC116500179
gene id: 219594:LOC116500179
uniprot id: A0A6J3EG26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. BTN/MOG family.
messages: Membrane

219594:AFF4
gene id: 219594:AFF4
uniprot id: A0A6J3DM90
names: Similarity
messages: Belongs to the AF4 family.

219594:ELP1
gene id: 219594:ELP1
uniprot id: A0A6J3EIX6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELP1/IKA1 family.
messages: Component of the elongator complex which is required for multiple tRNA modifications, including mcm5U (5-methoxycarbonylmethyl uridine), mcm5s2U (5-methoxycarbonylmethyl-2-thiouridine), and ncm5U (5-carbamoylmethyl uridine). The elongator complex catalyzes formation of carboxymethyluridine in the wobble base at position 34 in tRNAs.
messages: Cytoplasm
messages: Nucleus

219594:WDR82
gene id: 219594:WDR82
uniprot id: A0A6J3DKM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat SWD2 family.
messages: Nucleus

219594:TENM1
gene id: 219594:TENM1
uniprot id: A0A6J3DL74
uniprot id: A0A6J3DNM3
uniprot id: A0A6J3DNM8
uniprot id: A0A6J3DQI4
uniprot id: A0A6J3DRJ5
uniprot id: A0A6J3DSJ0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tenascin family. Teneurin subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

219594:SPON2
gene id: 219594:SPON2
uniprot id: A0A6J3CX96
uniprot id: A0A6J3D0Q6
names: Subcellular Location Annotation
messages: extracellular matrix

219594:DLGAP1
gene id: 219594:DLGAP1
uniprot id: A0A6J3CFC6
uniprot id: A0A6J3CI05
uniprot id: A0A6J3CJW8
names: Similarity
messages: Belongs to the SAPAP family.

219594:THPO
gene id: 219594:THPO
uniprot id: A0A6J3DIK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPO/TPO family.
messages: Secreted

219594:CLIC4
gene id: 219594:CLIC4
uniprot id: A0A6J3E2Z5
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel CLIC family.
messages: Cytoplasm
messages: Members of this family may change from a globular, soluble state to a state where the N-terminal domain is inserted into the membrane and functions as chloride channel. A conformation change of the N-terminal domain is thought to expose hydrophobic surfaces that trigger membrane insertion.
messages: Membrane

219594:NPBWR1
gene id: 219594:NPBWR1
uniprot id: A0A6J3CLQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:TSPAN14
gene id: 219594:TSPAN14
uniprot id: A0A6J3D5D8
uniprot id: A0A6J3D8L2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

219594:LOC116495403
gene id: 219594:LOC116495403
uniprot id: C7EK60
names: Similarity
messages: Belongs to the globin family.

219594:TNFRSF11B
gene id: 219594:TNFRSF11B
uniprot id: A0A6J3CKC0
uniprot id: A0A6J3CLJ7
names: Caution
names: Function
names: Subunit
messages: Acts as decoy receptor for TNFSF11/RANKL and thereby neutralizes its function in osteoclastogenesis.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:DDIT4
gene id: 219594:DDIT4
uniprot id: A0A6J3D773
names: Similarity
messages: Belongs to the DDIT4 family.

219594:BLCAP
gene id: 219594:BLCAP
uniprot id: A0A6J3DZ46
names: Similarity
messages: Belongs to the BLCAP family.

219594:PUSL1
gene id: 219594:PUSL1
uniprot id: A0A6J3E5R5
names: Similarity
messages: Belongs to the tRNA pseudouridine synthase TruA family.

219594:STARD13
gene id: 219594:STARD13
uniprot id: A0A6J3D3W3
uniprot id: A0A6J3D481
uniprot id: A0A6J3D6H1
uniprot id: A0A6J3D7D4
names: Subcellular Location Annotation
messages: Cytoplasm

219594:TRIM9
gene id: 219594:TRIM9
uniprot id: A0A6J3D0Z2
uniprot id: A0A6J3D3B9
uniprot id: A0A6J3D5W3
uniprot id: A0A6J3D6S5
uniprot id: A0A6J3D6S9
names: Subcellular Location Annotation
messages: cytoskeleton

219594:ADRB2
gene id: 219594:ADRB2
uniprot id: A0A6J3DM35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:RSBN1L
gene id: 219594:RSBN1L
uniprot id: A0A6J3D656
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the round spermatid basic protein 1 family.
messages: Nucleus

219594:LOC116491433
gene id: 219594:LOC116491433
uniprot id: A0A6J3DAJ0
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.

219594:PTGR2
gene id: 219594:PTGR2
uniprot id: A0A6J3D1A8
uniprot id: A0A6J3D4T8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NADP-dependent oxidoreductase L4BD family.
messages: Cytoplasm
messages: Monomer.

219594:FXYD2
gene id: 219594:FXYD2
uniprot id: A0A6J3E704
names: Similarity
messages: Belongs to the FXYD family.

219594:LOC116489440
gene id: 219594:LOC116489440
uniprot id: A0A6J3D294
names: Similarity
messages: Belongs to the beta type-B retroviral polymerase family. HERV class-II K(HML-2) pol subfamily.

219594:NASP
gene id: 219594:NASP
uniprot id: A0A6J3DAF8
uniprot id: A0A6J3DE34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NASP family.
messages: Nucleus

219594:NMT1
gene id: 219594:NMT1
uniprot id: A0A6J3E4M0
names: Function
names: Similarity
messages: Adds a myristoyl group to the N-terminal glycine residue of certain cellular proteins.
messages: Belongs to the NMT family.

219594:CPA6
gene id: 219594:CPA6
uniprot id: A0A6J3CG33
names: Similarity
messages: Belongs to the peptidase M14 family.

219594:LOC116490099
gene id: 219594:LOC116490099
uniprot id: A0A6J3D0T5
names: Similarity
messages: Belongs to the serpin family.

219594:PCCA
gene id: 219594:PCCA
uniprot id: A0A6J3E6W3
names: Subcellular Location Annotation
messages: Mitochondrion matrix

219594:CPLX3
gene id: 219594:CPLX3
uniprot id: A0A6J3DNR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complexin/synaphin family.
messages: Synapse

219594:STEAP3
gene id: 219594:STEAP3
uniprot id: A0A6J3D445
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STEAP family.
messages: Endosome membrane
messages: Membrane

219594:ALDH1L2
gene id: 219594:ALDH1L2
uniprot id: A0A6J3EQ74
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.
messages: In the C-terminal section; belongs to the aldehyde dehydrogenase family. ALDH1L subfamily.
messages: In the N-terminal section; belongs to the GART family.

219594:NMBR
gene id: 219594:NMBR
uniprot id: A0A6J3CRF7
uniprot id: A0A6J3CTR9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:PLK4
gene id: 219594:PLK4
uniprot id: A0A6J3CWM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDC5/Polo subfamily.
messages: centriole

219594:DLX6
gene id: 219594:DLX6
uniprot id: A0A6J3CQR0
names: Subcellular Location Annotation
messages: Nucleus

219594:CPNE7
gene id: 219594:CPNE7
uniprot id: A0A6J3DK47
uniprot id: A0A6J3DQL3
names: Similarity
messages: Belongs to the copine family.

219594:LOC116496669
gene id: 219594:LOC116496669
uniprot id: A0A6J3E0W3
names: Similarity
messages: Belongs to the cytochrome P450 family.

219594:MICOS10
gene id: 219594:MICOS10
uniprot id: A0A6J3E7V2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MICOS complex subunit Mic10 family.
messages: Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.
messages: Component of the mitochondrial contact site and cristae organizing system (MICOS) complex.
messages: Membrane
messages: Mitochondrion inner membrane

219594:NPC1
gene id: 219594:NPC1
uniprot id: A0A6J3CH75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the patched family.
messages: Membrane

219594:GTPBP1
gene id: 219594:GTPBP1
uniprot id: A0A6J3E7G7
names: Function
messages: Promotes degradation of target mRNA species. Plays a role in the regulation of circadian mRNA stability. Binds GTP and has GTPase activity.

219594:LOC116501896
gene id: 219594:LOC116501896
uniprot id: A0A6J3EPX0
names: Similarity
messages: Belongs to the CRISP family.

219594:DNAH11
gene id: 219594:DNAH11
uniprot id: A0A6J3CEM0
names: Similarity
messages: Belongs to the dynein heavy chain family.

219594:NKRF
gene id: 219594:NKRF
uniprot id: A0A6J3DQW2
names: Similarity
messages: Belongs to the CARF family.

219594:TRPC4
gene id: 219594:TRPC4
uniprot id: A0A6J3ELL3
names: Subcellular Location Annotation
messages: Membrane

219594:LOC116501430
gene id: 219594:LOC116501430
uniprot id: A0A6J3ELZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:LOC116500950
gene id: 219594:LOC116500950
uniprot id: A0A6J3ELE3
names: Similarity
messages: Belongs to the EGF-CFC (Cripto-1/FRL1/Cryptic) family.

219594:XKR8
gene id: 219594:XKR8
uniprot id: A0A6J3E9U0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XK family.
messages: Membrane

219594:LOC116501314
gene id: 219594:LOC116501314
uniprot id: A0A6J3EMV0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:LOC116494205
gene id: 219594:LOC116494205
uniprot id: A0A6J3DPE9
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

219594:ZHX1
gene id: 219594:ZHX1
uniprot id: A0A6J3CES3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZHX family.
messages: Nucleus

219594:SMPX
gene id: 219594:SMPX
uniprot id: A0A6J3DP15
names: Function
names: Similarity
messages: Belongs to the SMPX family.
messages: Plays a role in the regulatory network through which muscle cells coordinate their structural and functional states during growth, adaptation, and repair.

219594:PSMD4
gene id: 219594:PSMD4
uniprot id: A0A6J3EAS8
names: Similarity
messages: Belongs to the proteasome subunit S5A family.

219594:MYOF
gene id: 219594:MYOF
uniprot id: A0A6J3D5G9
uniprot id: A0A6J3D5H6
uniprot id: A0A6J3D869
uniprot id: A0A6J3D8P8
uniprot id: A0A6J3DAW0
uniprot id: A0A6J3DAW5
uniprot id: A0A6J3DBD5
uniprot id: A0A6J3DBE1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferlin family.
messages: Cytoplasmic vesicle membrane
messages: Membrane

219594:CPLX4
gene id: 219594:CPLX4
uniprot id: A0A6J3EKQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complexin/synaphin family.
messages: Synapse

219594:MARVELD2
gene id: 219594:MARVELD2
uniprot id: A0A6J3ELB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELL/occludin family.
messages: Cell membrane
messages: Membrane
messages: tight junction

219594:VPS13C
gene id: 219594:VPS13C
uniprot id: A0A6J3DKN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS13 family.
messages: Lipid droplet

219594:GUCY1A1
gene id: 219594:GUCY1A1
uniprot id: A0A6J3CX65
uniprot id: A0A6J3CXJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Cytoplasm

219594:SLC45A1
gene id: 219594:SLC45A1
uniprot id: A0A6J3E131
uniprot id: A0A6J3E2F7
names: Subcellular Location Annotation
messages: Membrane

219594:SLC10A4
gene id: 219594:SLC10A4
uniprot id: A0A6J3D0G4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bile acid:sodium symporter (BASS) (TC 2.A.28) family.
messages: Membrane

219594:TRNT1
gene id: 219594:TRNT1
uniprot id: A0A6J3DHN6
uniprot id: A0A6J3DL34
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

219594:MSI1
gene id: 219594:MSI1
uniprot id: A0A6J3DV06
uniprot id: A0A6J3DZV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Musashi family.
messages: Cytoplasm

219594:GALNTL6
gene id: 219594:GALNTL6
uniprot id: A0A6J3D0L7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

219594:CLEC16A
gene id: 219594:CLEC16A
uniprot id: A0A6J3DQ61
names: Similarity
messages: Belongs to the CLEC16A/gop-1 family.

219594:SETD3
gene id: 219594:SETD3
uniprot id: A0A6J3D1Z9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class V-like SAM-binding methyltransferase superfamily. SETD3 actin-histidine methyltransferase family.
messages: Cytoplasm

219594:SUSD6
gene id: 219594:SUSD6
uniprot id: A0A6J3CZL6
uniprot id: A0A6J3D1V6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:RYR3
gene id: 219594:RYR3
uniprot id: A0A6J3D1W0
uniprot id: A0A6J3D1W7
uniprot id: A0A6J3D4A0
uniprot id: A0A6J3D4M5
uniprot id: A0A6J3D4M9
uniprot id: A0A6J3D6V4
uniprot id: A0A6J3D7P8
uniprot id: A0A6J3D7Q4
names: Subcellular Location Annotation
messages: Membrane
messages: Sarcoplasmic reticulum membrane

219594:NAP1L4
gene id: 219594:NAP1L4
uniprot id: A0A6J3CXA1
uniprot id: A0A6J3CZJ8
uniprot id: A0A6J3CZK3
names: Similarity
messages: Belongs to the nucleosome assembly protein (NAP) family.

219594:KCNK1
gene id: 219594:KCNK1
uniprot id: A0A6J3CNP5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Cell membrane
messages: Cytoplasmic vesicle
messages: Endosome
messages: Membrane
messages: Perikaryon
messages: Recycling endosome
messages: Synaptic cell membrane
messages: Vesicle
messages: dendrite

219594:SRP72
gene id: 219594:SRP72
uniprot id: A0A6J3D1H9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SRP72 family.
messages: Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER).
messages: Cytoplasm

219594:LDB2
gene id: 219594:LDB2
uniprot id: A0A6J3CTS7
uniprot id: A0A6J3CTT0
uniprot id: A0A6J3CW27
uniprot id: A0A6J3CWG9
uniprot id: A0A6J3CZV7
uniprot id: A0A6J3CZW1
names: Similarity
messages: Belongs to the LDB family.

219594:DYDC1
gene id: 219594:DYDC1
uniprot id: A0A6J3DA35
names: Similarity
messages: Belongs to the dpy-30 family.

219594:TAC3
gene id: 219594:TAC3
uniprot id: A0A6J3EBN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tachykinin family.
messages: Secreted

219594:COG3
gene id: 219594:COG3
uniprot id: A0A6J3DV88
names: Function
names: Similarity
messages: Belongs to the COG3 family.
messages: Involved in ER-Golgi transport.

219594:LOC116485692
gene id: 219594:LOC116485692
uniprot id: A0A6J3CF73
names: Similarity
names: Subunit
messages: Belongs to the avian keratin family.
messages: The avian keratins (F-ker, S-ker, C-ker and B-ker) are a complex mixture of very similar polypeptides.

219594:LOC116498541
gene id: 219594:LOC116498541
uniprot id: A0A6J3EB59
names: Similarity
names: Subunit
messages: Belongs to the avian keratin family.
messages: The avian keratins (F-ker, S-ker, C-ker and B-ker) are a complex mixture of very similar polypeptides.

219594:SLC45A3
gene id: 219594:SLC45A3
uniprot id: A0A6J3EAI4
names: Subcellular Location Annotation
messages: Membrane

219594:LOC116494857
gene id: 219594:LOC116494857
uniprot id: A0A6J3DU65
names: Subcellular Location Annotation
messages: Cytoplasm

219594:CDS2
gene id: 219594:CDS2
uniprot id: A0A6J3E9T1
uniprot id: A0A6J3ECY9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Catalyzes the conversion of phosphatidic acid (PA) to CDP-diacylglycerol (CDP-DAG), an essential intermediate in the synthesis of phosphatidylglycerol, cardiolipin and phosphatidylinositol.
messages: Membrane

219594:HOXD9
gene id: 219594:HOXD9
uniprot id: A0A6J3D7G3
uniprot id: A0A6J3D7Y7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

219594:PCSK9
gene id: 219594:PCSK9
uniprot id: A0A6J3D9K0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S8 family.
messages: Cell surface
messages: Cytoplasm
messages: Endoplasmic reticulum
messages: Endosome
messages: Golgi apparatus
messages: Lysosome

219594:LOC116492592
gene id: 219594:LOC116492592
uniprot id: A0A6J3DCT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the reduced folate carrier (RFC) transporter (TC 2.A.48) family.
messages: Membrane

219594:PPFIBP2
gene id: 219594:PPFIBP2
uniprot id: A0A6J3CWN9
uniprot id: A0A6J3CWP4
uniprot id: A0A6J3CYW9
uniprot id: A0A6J3CYX5
uniprot id: A0A6J3CZ80
uniprot id: A0A6J3D1H1
uniprot id: A0A6J3D2L3
names: Similarity
messages: Belongs to the liprin family. Liprin-beta subfamily.

219594:ST6GALNAC1
gene id: 219594:ST6GALNAC1
uniprot id: A0A6J3DZI6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

219594:PPARGC1A
gene id: 219594:PPARGC1A
uniprot id: A0A6J3CTI2
uniprot id: A0A6J3CYL3
names: Subcellular Location Annotation
messages: PML body

219594:DEDD
gene id: 219594:DEDD
uniprot id: A0A6J3EEP6
names: Subcellular Location Annotation
messages: nucleolus

219594:FAT4
gene id: 219594:FAT4
uniprot id: A0A6J3CZB4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:SEH1L
gene id: 219594:SEH1L
uniprot id: A0A6J3CG54
uniprot id: A0A6J3CME6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat SEC13 family.
messages: Component of the Nup107-160 subcomplex of the nuclear pore complex (NPC). The Nup107-160 subcomplex is required for the assembly of a functional NPC. The Nup107-160 subcomplex is also required for normal kinetochore microtubule attachment, mitotic progression and chromosome segregation. This subunit plays a role in recruitment of the Nup107-160 subcomplex to the kinetochore.
messages: Lysosome membrane
messages: kinetochore

219594:RAP2C
gene id: 219594:RAP2C
uniprot id: A0A6J3DRX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Ras family.
messages: Endosome membrane
messages: Recycling endosome membrane

219594:SEMA4B
gene id: 219594:SEMA4B
uniprot id: A0A6J3DK33
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:LOC116500796
gene id: 219594:LOC116500796
uniprot id: A0A6J3EKQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

219594:FAT3
gene id: 219594:FAT3
uniprot id: A0A6J3DKP3
uniprot id: A0A6J3DR66
uniprot id: A0A6J3DR72
uniprot id: A0A6J3DS09
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:MID1IP1
gene id: 219594:MID1IP1
uniprot id: A0A6J3EJA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPOT14 family.
messages: Cytoplasm
messages: Nucleus

219594:METTL16
gene id: 219594:METTL16
uniprot id: A0A6J3EP45
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. METTL16/RlmF family.
messages: RNA N6-methyltransferase that methylates adenosine residues at the N(6) position of a subset of RNAs and is involved in S-adenosyl-L-methionine homeostasis by regulating expression of MAT2A transcripts. Able to N6-methylate a subset of mRNAs and U6 small nuclear RNAs (U6 snRNAs). In contrast to the METTL3-METTL14 heterodimer, only able to methylate a limited number of RNAs: requires both a 5'UACAGAGAA-3' nonamer sequence and a specific RNA structure.

219594:ABCG2
gene id: 219594:ABCG2
uniprot id: A0A6J3CWR5
uniprot id: A0A6J3CX40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCG family. Eye pigment precursor importer (TC 3.A.1.204) subfamily.
messages: Cell membrane
messages: Membrane
messages: Mitochondrion membrane

219594:CP
gene id: 219594:CP
uniprot id: A0A6J3DBH6
names: Similarity
messages: Belongs to the multicopper oxidase family.

219594:LOC116491306
gene id: 219594:LOC116491306
uniprot id: A0A6J3D9Z3
names: Caution
names: Similarity
messages: Belongs to the ZP domain family. ZPB subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:MFAP3
gene id: 219594:MFAP3
uniprot id: A0A6J3DSC8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

219594:UTRN
gene id: 219594:UTRN
uniprot id: A0A6J3CSA9
uniprot id: A0A6J3CW75
names: Function
names: Subcellular Location Annotation
messages: May play a role in anchoring the cytoskeleton to the plasma membrane.
messages: cytoskeleton

219594:LOC116499642
gene id: 219594:LOC116499642
uniprot id: A0A6J3EE50
names: Similarity
names: Subunit
messages: Belongs to the avian keratin family.
messages: The avian keratins (F-ker, S-ker, C-ker and B-ker) are a complex mixture of very similar polypeptides.

219594:MAP7D2
gene id: 219594:MAP7D2
uniprot id: A0A6J3D2J7
uniprot id: A0A6J3D2L5
uniprot id: A0A6J3D5C3
uniprot id: A0A6J3D5G0
uniprot id: A0A6J3D7P7
uniprot id: A0A6J3D8G7
names: Similarity
messages: Belongs to the MAP7 family.

219594:LOC116494270
gene id: 219594:LOC116494270
uniprot id: A0A6J3DPN3
names: Similarity
messages: Belongs to the aldo/keto reductase family.

219594:ATP10D
gene id: 219594:ATP10D
uniprot id: A0A6J3CW84
uniprot id: A0A6J3CWM5
uniprot id: A0A6J3CZ11
uniprot id: A0A6J3D043
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

219594:KPNA2
gene id: 219594:KPNA2
uniprot id: A0A6J3E0U5
names: Similarity
messages: Belongs to the importin alpha family.

219594:MBOAT2
gene id: 219594:MBOAT2
uniprot id: A0A6J3CTN8
names: Subcellular Location Annotation
messages: Membrane

219594:STK3
gene id: 219594:STK3
uniprot id: A0A6J3CIT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.
messages: Nucleus

219594:ZC3H12B
gene id: 219594:ZC3H12B
uniprot id: A0A6J3DMZ0
names: Similarity
messages: Belongs to the ZC3H12 family.

219594:LOC116494279
gene id: 219594:LOC116494279
uniprot id: A0A6J3DMV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM182 family.
messages: Cell membrane
messages: Membrane

219594:DCLRE1A
gene id: 219594:DCLRE1A
uniprot id: A0A6J3D7L1
uniprot id: A0A6J3DDJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA repair metallo-beta-lactamase (DRMBL) family.
messages: Nucleus

219594:TENT5D
gene id: 219594:TENT5D
uniprot id: A0A6J3DR65
names: Similarity
messages: Belongs to the TENT family.

219594:LOC116500118
gene id: 219594:LOC116500118
uniprot id: A0A6J3EFW9
names: Subcellular Location Annotation
messages: Membrane

219594:CCM2L
gene id: 219594:CCM2L
uniprot id: A0A6J3DUJ2
names: Similarity
messages: Belongs to the CCM2 family.

219594:GREM1
gene id: 219594:GREM1
uniprot id: A0A6J3D193
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DAN family.
messages: Secreted

219594:FABP6
gene id: 219594:FABP6
uniprot id: A0A6J3DQU3
uniprot id: A0A6J3DSV3
uniprot id: A0A6J3DTR5
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

219594:SHMT1
gene id: 219594:SHMT1
uniprot id: A0A6J3DUI2
names: Function
names: Similarity
messages: Belongs to the SHMT family.
messages: Interconversion of serine and glycine.

219594:PTEN
gene id: 219594:PTEN
uniprot id: A0A6J3D9S9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine-phosphorylated proteins. Also acts as a lipid phosphatase, removing the phosphate in the D3 position of the inositol ring from phosphatidylinositol 3,4,5-trisphosphate, phosphatidylinositol 3,4-diphosphate, phosphatidylinositol 3-phosphate and inositol 1,3,4,5-tetrakisphosphate with order of substrate preference in vitro PtdIns(3,4,5)P3 > PtdIns(3,4)P2 > PtdIns3P > Ins(1,3,4,5)P4.
messages: Belongs to the PTEN phosphatase protein family.
messages: Cytoplasm
messages: Nucleus
messages: PML body
messages: Postsynaptic density
messages: dendritic spine

219594:FMN1
gene id: 219594:FMN1
uniprot id: A0A6J3D6W0
names: Similarity
messages: Belongs to the formin homology family. Cappuccino subfamily.

219594:HSPA4L
gene id: 219594:HSPA4L
uniprot id: A0A6J3D2J0
names: Similarity
messages: Belongs to the heat shock protein 70 family.

219594:SHROOM4
gene id: 219594:SHROOM4
uniprot id: A0A6J3DMQ5
uniprot id: A0A6J3DPI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the shroom family.
messages: cytoskeleton

219594:EIF1AX
gene id: 219594:EIF1AX
uniprot id: A0A6J3DVE9
names: Function
names: Similarity
messages: Belongs to the eIF-1A family.
messages: Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits.

219594:SGSM1
gene id: 219594:SGSM1
uniprot id: A0A6J3DUK6
uniprot id: A0A6J3DZG3
names: Similarity
messages: Belongs to the RUTBC family.

219594:LOC116489852
gene id: 219594:LOC116489852
uniprot id: A0A6J3D215
uniprot id: A0A6J3D229
uniprot id: A0A6J3D5F8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M28 family. M28B subfamily.
messages: Cell membrane
messages: Membrane

219594:FH
gene id: 219594:FH
uniprot id: A0A6J3CJH5
names: Function
names: Similarity
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Catalyzes the hydration of fumarate to L-malate in the tricarboxylic acid (TCA) cycle to facilitate a transition step in the production of energy in the form of NADH.

219594:MPDZ
gene id: 219594:MPDZ
uniprot id: A0A6J3EEH0
uniprot id: A0A6J3EEH3
uniprot id: A0A6J3EEH9
uniprot id: A0A6J3EFW7
uniprot id: A0A6J3EFX4
uniprot id: A0A6J3EJH2
uniprot id: A0A6J3EJI2
uniprot id: A0A6J3EJI8
uniprot id: A0A6J3EJJ6
uniprot id: A0A6J3EJL8
uniprot id: A0A6J3EJM3
uniprot id: A0A6J3EJM8
uniprot id: A0A6J3EL75
uniprot id: A0A6J3EL80
uniprot id: A0A6J3EL85
names: Subcellular Location Annotation
messages: tight junction

219594:AIP
gene id: 219594:AIP
uniprot id: A0A6J3D164
names: Subcellular Location Annotation
messages: Cytoplasm

219594:PITPNM2
gene id: 219594:PITPNM2
uniprot id: A0A6J3DUV4
uniprot id: A0A6J3DYY5
uniprot id: A0A6J3DZQ2
uniprot id: A0A6J3E0S2
names: Similarity
messages: Belongs to the PtdIns transfer protein family. PI transfer class IIA subfamily.

219594:CACNA1S
gene id: 219594:CACNA1S
uniprot id: A0A6J3EC39
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family.
messages: Membrane
messages: Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death.

219594:GRIN2C
gene id: 219594:GRIN2C
uniprot id: A0A6J3E0G2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.
messages: Synaptic cell membrane

219594:MRTFB
gene id: 219594:MRTFB
uniprot id: A0A6J3DRB9
names: Similarity
names: Subunit
messages: Belongs to the phosphatase and actin regulator family.
messages: Binds PPP1CA and actin.

219594:ZNF488
gene id: 219594:ZNF488
uniprot id: A0A6J3DCW2
names: Subcellular Location Annotation
messages: Nucleus

219594:WNT9B
gene id: 219594:WNT9B
uniprot id: A0A6J3E562
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

219594:LOC116488669
gene id: 219594:LOC116488669
uniprot id: A0A6J3CVJ4
uniprot id: A0A6J3CVZ7
names: Similarity
messages: Belongs to the cytochrome P450 family.

219594:EDA
gene id: 219594:EDA
uniprot id: A0A6J3DQU2
names: Similarity
messages: Belongs to the tumor necrosis factor family.

219594:DCTN6
gene id: 219594:DCTN6
uniprot id: A0A6J3CYS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dynactin subunits 5/6 family. Dynactin subunit 6 subfamily.
messages: cytoskeleton

219594:SUMO2
gene id: 219594:SUMO2
uniprot id: A0A6J3DW33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ubiquitin family. SUMO subfamily.
messages: Nucleus

219594:TRABD2A
gene id: 219594:TRABD2A
uniprot id: A0A6J3EDT6
uniprot id: A0A6J3EJ36
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TIKI family.
messages: Cell membrane
messages: Divalent metal cations. Mn(2+) or Co(2+).
messages: Membrane
messages: Metalloprotease that acts as a negative regulator of the Wnt signaling pathway by mediating the cleavage of the N-terminal residues of a subset of Wnt proteins. Following cleavage, Wnt proteins become oxidized and form large disulfide-bond oligomers, leading to their inactivation.

219594:TIMP2
gene id: 219594:TIMP2
uniprot id: A0A6J3E0K3
names: Similarity
messages: Belongs to the protease inhibitor I35 (TIMP) family.

219594:TMOD4
gene id: 219594:TMOD4
uniprot id: A0A6J3EG53
names: Subcellular Location Annotation
messages: cytoskeleton

219594:SMO
gene id: 219594:SMO
uniprot id: A0A6J3DVE8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor Fz/Smo family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

219594:DMAP1
gene id: 219594:DMAP1
uniprot id: A0A6J3DH25
names: Subcellular Location Annotation
messages: Nucleus

219594:LOC116500794
gene id: 219594:LOC116500794
uniprot id: A0A6J3EDY2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:LOXL3
gene id: 219594:LOXL3
uniprot id: A0A6J3CWA5
uniprot id: A0A6J3CYH8
uniprot id: A0A6J3D130
uniprot id: A0A6J3D135
uniprot id: A0A6J3D279
uniprot id: A0A6J3D284
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lysyl oxidase family.
messages: Contains 1 lysine tyrosylquinone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mediates the post-translational oxidative deamination of lysine residues on target proteins leading to the formation of deaminated lysine (allysine).
messages: The lysine tyrosylquinone cross-link (LTQ) is generated by condensation of the epsilon-amino group of a lysine with a topaquinone produced by oxidation of tyrosine.
messages: extracellular space

219594:LDHD
gene id: 219594:LDHD
uniprot id: A0A6J3DQQ3
names: Similarity
messages: Belongs to the FAD-binding oxidoreductase/transferase type 4 family.

219594:LAMP5
gene id: 219594:LAMP5
uniprot id: A0A6J3CWC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LAMP family.
messages: Endosome membrane

219594:PATL1
gene id: 219594:PATL1
uniprot id: A0A6J3D3X9
names: Similarity
messages: Belongs to the PAT1 family.

219594:GALNT15
gene id: 219594:GALNT15
uniprot id: A0A6J3CGL0
uniprot id: A0A6J3CJG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

219594:TMEM168
gene id: 219594:TMEM168
uniprot id: A0A6J3E8R1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM168 family.
messages: Membrane

219594:TRPC3
gene id: 219594:TRPC3
uniprot id: A0A6J3D1L2
names: Subcellular Location Annotation
messages: Membrane

219594:LOC116495388
gene id: 219594:LOC116495388
uniprot id: A0A6J3DVN8
names: Similarity
messages: Belongs to the DNase I family.

219594:DCAF13
gene id: 219594:DCAF13
uniprot id: A0A6J3CMM3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat DCAF13/WDSOF1 family.
messages: nucleolus

219594:HOXA6
gene id: 219594:HOXA6
uniprot id: A0A6J3CKW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus

219594:LOC116502128
gene id: 219594:LOC116502128
uniprot id: A0A6J3EPE8
names: Similarity
messages: Belongs to the Arg-specific ADP-ribosyltransferase family.

219594:ADAMTS18
gene id: 219594:ADAMTS18
uniprot id: A0A6J3DIP2
uniprot id: A0A6J3DL77
uniprot id: A0A6J3DMT2
uniprot id: A0A6J3DP58
uniprot id: A0A6J3DPU1
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

219594:KCNA2
gene id: 219594:KCNA2
uniprot id: A0A6J3ECB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the potassium channel family. A (Shaker) (TC 1.A.1.2) subfamily. Kv1.2/KCNA2 sub-subfamily.
messages: Cell membrane
messages: Membrane

219594:HVCN1
gene id: 219594:HVCN1
uniprot id: A0A6J3DXJ3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the hydrogen channel family.
messages: Homodimer.
messages: Membrane

219594:ACOX1
gene id: 219594:ACOX1
uniprot id: A0A6J3E0V1
uniprot id: A0A6J3E200
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acyl-CoA oxidase family.
messages: Peroxisome

219594:RPL4
gene id: 219594:RPL4
uniprot id: A0A6J3DNH2
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Component of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.

219594:LOC116499719
gene id: 219594:LOC116499719
uniprot id: A0A6J3EGI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the S-100 family.
messages: Cytoplasm
messages: Nucleus
messages: Secreted

219594:LOC116501449
gene id: 219594:LOC116501449
uniprot id: A0A6J3ENE0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:MFAP2
gene id: 219594:MFAP2
uniprot id: A0A6J3E6C6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MFAP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

219594:NDUFAF3
gene id: 219594:NDUFAF3
uniprot id: A0A6J3DF98
names: Function
names: Subcellular Location Annotation
messages: Essential factor for the assembly of mitochondrial NADH:ubiquinone oxidoreductase complex (complex I).
messages: Membrane
messages: Mitochondrion inner membrane
messages: Nucleus

219594:BSG
gene id: 219594:BSG
uniprot id: A0A6J3E9G1
names: Subcellular Location Annotation
messages: Basolateral cell membrane
messages: Cell membrane
messages: Endoplasmic reticulum membrane
messages: Lateral cell membrane

219594:CD47
gene id: 219594:CD47
uniprot id: A0A6J3CRK3
uniprot id: A0A6J3CRL8
uniprot id: A0A6J3CTX1
uniprot id: A0A6J3CXQ8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

219594:HSPB2
gene id: 219594:HSPB2
uniprot id: A0A6J3E894
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

219594:ENOPH1
gene id: 219594:ENOPH1
uniprot id: A0A6J3CX35
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HAD-like hydrolase superfamily. MasA/MtnC family.
messages: Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Nucleus

219594:HK2
gene id: 219594:HK2
uniprot id: A0A6J3EFD9
names: Similarity
messages: Belongs to the hexokinase family.

219594:LRP12
gene id: 219594:LRP12
uniprot id: A0A6J3CFC8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:TAF1
gene id: 219594:TAF1
uniprot id: A0A6J3DQT7
uniprot id: A0A6J3DRL2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF1 family.
messages: Nucleus

219594:VILL
gene id: 219594:VILL
uniprot id: A0A6J3CFF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the villin/gelsolin family.
messages: filopodium tip
messages: lamellipodium
messages: microvillus
messages: ruffle

219594:ALG5
gene id: 219594:ALG5
uniprot id: A0A6J3EJ25
uniprot id: A0A6J3EMY4
names: Similarity
messages: Belongs to the glycosyltransferase 2 family.

219594:LOC116498677
gene id: 219594:LOC116498677
uniprot id: A0A6J3E5H5
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family.

219594:CCNI
gene id: 219594:CCNI
uniprot id: A0A6J3CZN7
names: Similarity
messages: Belongs to the cyclin family.

219594:MTMR9
gene id: 219594:MTMR9
uniprot id: A0A6J3CP30
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.

219594:PPIC
gene id: 219594:PPIC
uniprot id: A0A6J3EI91
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

219594:CPT1B
gene id: 219594:CPT1B
uniprot id: A0A6J3DP71
names: Similarity
messages: Belongs to the carnitine/choline acetyltransferase family.

219594:ELOVL3
gene id: 219594:ELOVL3
uniprot id: A0A6J3D742
uniprot id: A0A6J3DAH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELO family.
messages: Membrane

219594:LOC116499699
gene id: 219594:LOC116499699
uniprot id: A0A6J3EB53
names: Function
names: Similarity
messages: Belongs to the S-100 family.
messages: May function as calcium sensor and modulator, contributing to cellular calcium signaling. May function by interacting with other proteins, such as TPR-containing proteins, and indirectly play a role in many physiological processes such as the reorganization of the actin cytoskeleton and in cell motility. Binds 2 calcium ions. Calcium binding is cooperative.

219594:SYNPR
gene id: 219594:SYNPR
uniprot id: A0A6J3DJU1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptophysin/synaptobrevin family.
messages: Membrane

219594:FAM83B
gene id: 219594:FAM83B
uniprot id: A0A6J3CTU6
names: Similarity
messages: Belongs to the FAM83 family.

219594:EXT1
gene id: 219594:EXT1
uniprot id: A0A6J3CLC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 47 family.
messages: Endoplasmic reticulum membrane

219594:CCNYL1
gene id: 219594:CCNYL1
uniprot id: A0A6J3D3P1
uniprot id: A0A6J3D8Z7
names: Similarity
messages: Belongs to the cyclin family. Cyclin Y subfamily.

219594:PSMC2
gene id: 219594:PSMC2
uniprot id: A0A6J3EK08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family.
messages: Cytoplasm

219594:CLUAP1
gene id: 219594:CLUAP1
uniprot id: A0A6J3DW50
uniprot id: A0A6J3DX18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CLUAP1 family.
messages: cilium

219594:LOC116494089
gene id: 219594:LOC116494089
uniprot id: A0A6J3DQ50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

219594:ZCCHC4
gene id: 219594:ZCCHC4
uniprot id: A0A6J3CVU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZCCHC4 family.
messages: Cytoplasm
messages: nucleolus

219594:CDPF1
gene id: 219594:CDPF1
uniprot id: A0A6J3E6R1
uniprot id: A0A6J3E9Q9
names: Similarity
messages: Belongs to the CDPF1 family.

219594:LOC116490398
gene id: 219594:LOC116490398
uniprot id: A0A6J3D4M6
names: Similarity
messages: Belongs to the serpin family.

219594:LOC116486794
gene id: 219594:LOC116486794
uniprot id: A0A6J3CM85
names: Similarity
names: Subunit
messages: Belongs to the avian keratin family.
messages: The avian keratins (F-ker, S-ker, C-ker and B-ker) are a complex mixture of very similar polypeptides.

219594:NID1
gene id: 219594:NID1
uniprot id: A0A6J3CM87
uniprot id: A0A6J3CP17
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: basement membrane

219594:C12H16orf70
gene id: 219594:C12H16orf70
uniprot id: A0A6J3DPY7
names: Similarity
messages: Belongs to the PHAF1 family.

219594:MZT1
gene id: 219594:MZT1
uniprot id: A0A6J3DCE4
names: Function
names: Similarity
messages: Belongs to the MOZART1 family.
messages: Required for gamma-tubulin complex recruitment to the centrosome.

219594:LOC116486284
gene id: 219594:LOC116486284
uniprot id: A0A6J3CN48
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

219594:SLC35F4
gene id: 219594:SLC35F4
uniprot id: A0A6J3D0K8
uniprot id: A0A6J3D6F4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC35F solute transporter family.
messages: Membrane

219594:RAG1
gene id: 219594:RAG1
uniprot id: A0A6J3CYE2
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RAG1 family.
messages: Binds 1 divalent metal cation per subunit. Mg(2+) or Mn(2+).
messages: Catalytic component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination. V(D)J recombination assembles a diverse repertoire of immunoglobulin and T-cell receptor genes in developing B and T-lymphocytes through rearrangement of different V (variable), in some cases D (diversity), and J (joining) gene segments. In the RAG complex, RAG1 mediates the DNA-binding to the conserved recombination signal sequences (RSS) and catalyzes the DNA cleavage activities by introducing a double-strand break between the RSS and the adjacent coding segment. RAG2 is not a catalytic component but is required for all known catalytic activities. DNA cleavage occurs in 2 steps: a first nick is introduced in the top strand immediately upstream of the heptamer, generating a 3'-hydroxyl group that can attack the phosphodiester bond on the opposite strand in a direct transesterification reaction, thereby creating 4 DNA ends: 2 hairpin coding ends and 2 blunt, 5'-phosphorylated ends.
messages: Homodimer.
messages: Nucleus
messages: The NBD (nonamer binding) DNA-binding domain mediates the specific binding to the nonamer RSS motif by forming a tightly interwoven homodimer that binds and synapses 2 nonamer elements, with each NBD making contact with both DNA molecules. Each RSS is composed of well-conserved heptamer (consensus 5'-CACAGTG-3') and nonamer (consensus 5'-ACAAAAACC-3') sequences separated by a spacer of either 12 bp or 23 bp.

219594:SSBP2
gene id: 219594:SSBP2
uniprot id: A0A6J3EDN9
uniprot id: A0A6J3EII7
uniprot id: A0A6J3EIX0
uniprot id: A0A6J3EKH1
names: Subcellular Location Annotation
messages: Nucleus

219594:DDX3X
gene id: 219594:DDX3X
uniprot id: A0A6J3CM78
names: Similarity
messages: Belongs to the DEAD box helicase family.

219594:UNC5D
gene id: 219594:UNC5D
uniprot id: A0A6J3EF24
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the unc-5 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for netrin required for axon guidance. Mediates axon repulsion of neuronal growth cones in the developing nervous system upon ligand binding.

219594:DNMT1
gene id: 219594:DNMT1
uniprot id: A0A6J3EAY8
uniprot id: A0A6J3ECB2
uniprot id: A0A6J3EG03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.
messages: Nucleus

219594:LOC116498279
gene id: 219594:LOC116498279
uniprot id: A0A6J3E8H9
names: Similarity
messages: Belongs to the intermediate filament family.

219594:LOC116488123
gene id: 219594:LOC116488123
uniprot id: A0A6J3CTB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-17 family.
messages: Secreted

219594:IL2RB
gene id: 219594:IL2RB
uniprot id: A0A6J3EQ99
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type I cytokine receptor family. Type 4 subfamily.
messages: Cell membrane
messages: Membrane
messages: Non-covalent dimer of an alpha and a beta subunit. IL2R exists in 3 different forms: a high affinity dimer, an intermediate affinity monomer (beta subunit), and a low affinity monomer (alpha subunit). The high and intermediate affinity forms also associate with a gamma subunit. Interacts with SHB upon interleukin stimulation.

219594:LOC116492483
gene id: 219594:LOC116492483
uniprot id: A0A6J3DIG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SRP receptor beta subunit family.
messages: Endoplasmic reticulum membrane
messages: Membrane

219594:NIP7
gene id: 219594:NIP7
uniprot id: A0A6J3DLR4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NIP7 family.
messages: Interacts with pre-ribosome complex.
messages: Required for proper 34S pre-rRNA processing and 60S ribosome subunit assembly.
messages: nucleolus

219594:LOC116500342
gene id: 219594:LOC116500342
uniprot id: A0A6J3ED56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:PIGG
gene id: 219594:PIGG
uniprot id: A0A6J3EE77
uniprot id: A0A6J3EHP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGG/PIGN/PIGO family. PIGG subfamily.
messages: Endoplasmic reticulum membrane
messages: Membrane

219594:PJVK
gene id: 219594:PJVK
uniprot id: A0A6J3DB70
names: Similarity
messages: Belongs to the gasdermin family.

219594:ADD1
gene id: 219594:ADD1
uniprot id: A0A6J3CTX3
uniprot id: A0A6J3CTX7
uniprot id: A0A6J3CTY2
uniprot id: A0A6J3CW68
uniprot id: A0A6J3CW72
uniprot id: A0A6J3CW76
uniprot id: A0A6J3CWK8
uniprot id: A0A6J3CWL1
uniprot id: A0A6J3CWL6
uniprot id: A0A6J3CYZ7
uniprot id: A0A6J3CZ01
uniprot id: A0A6J3D001
uniprot id: A0A6J3D033
names: Similarity
messages: Belongs to the aldolase class II family. Adducin subfamily.

219594:GIPC3
gene id: 219594:GIPC3
uniprot id: A0A6J3E9K3
names: Similarity
messages: Belongs to the GIPC family.

219594:RRN3
gene id: 219594:RRN3
uniprot id: A0A6J3DUD7
names: Similarity
messages: Belongs to the RRN3 family.

219594:RGS5
gene id: 219594:RGS5
uniprot id: A0A6J3DEK8
uniprot id: A0A6J3DGR2
names: Function
messages: Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Binds to G(i)-alpha and G(o)-alpha, but not to G(s)-alpha.

219594:FRZB
gene id: 219594:FRZB
uniprot id: A0A6J3D7N6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the secreted frizzled-related protein (sFRP) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted
messages: Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP3/FRZB appears to be involved in limb skeletogenesis. Antagonist of Wnt8 signaling. Regulates chondrocyte maturation and long bone development.

219594:PPIL3
gene id: 219594:PPIL3
uniprot id: A0A6J3D7C3
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

219594:EIF1
gene id: 219594:EIF1
uniprot id: A0A6J3E582
names: Similarity
messages: Belongs to the SUI1 family.

219594:MINAR1
gene id: 219594:MINAR1
uniprot id: A0A6J3DLS6
names: Similarity
messages: Belongs to the MINAR family.

219594:INSR
gene id: 219594:INSR
uniprot id: A0A6J3E738
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. Insulin receptor subfamily.
messages: Membrane

219594:LOC116500346
gene id: 219594:LOC116500346
uniprot id: A0A6J3EBU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:UPF3B
gene id: 219594:UPF3B
uniprot id: A0A6J3DPY5
names: Similarity
messages: Belongs to the RENT3 family.

219594:TBX20
gene id: 219594:TBX20
uniprot id: A0A6J3CMV4
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

219594:MYOD1
gene id: 219594:MYOD1
uniprot id: A0A6J3D3G9
names: Subcellular Location Annotation
names: Subunit
messages: Efficient DNA binding requires dimerization with another bHLH protein.
messages: Nucleus

219594:CSF3R
gene id: 219594:CSF3R
uniprot id: A0A6J3E9N2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type I cytokine receptor family. Type 2 subfamily.
messages: Membrane

219594:LOC116498138
gene id: 219594:LOC116498138
uniprot id: A0A6J3EA70
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.

219594:ANAPC15
gene id: 219594:ANAPC15
uniprot id: A0A6J3DK67
names: Similarity
messages: Belongs to the APC15 family.

219594:TMEM182
gene id: 219594:TMEM182
uniprot id: A0A6J3EDY1
uniprot id: A0A6J3EHN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM182 family.
messages: Cell membrane
messages: Membrane

219594:LOC116500545
gene id: 219594:LOC116500545
uniprot id: A0A6J3EJJ4
names: Subcellular Location Annotation
messages: Nucleus

219594:NUP50
gene id: 219594:NUP50
uniprot id: A0A6J3CUA7
names: Subcellular Location Annotation
messages: nuclear pore complex

219594:P4HA3
gene id: 219594:P4HA3
uniprot id: A0A6J3DUZ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P4HA family.
messages: Catalyzes the post-translational formation of 4-hydroxyproline in -Xaa-Pro-Gly- sequences in collagens and other proteins.
messages: Endoplasmic reticulum lumen

219594:CEP57L1
gene id: 219594:CEP57L1
uniprot id: A0A6J3CUT2
names: Similarity
messages: Belongs to the translokin family.

219594:REEP4
gene id: 219594:REEP4
uniprot id: A0A6J3ED85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DP1 family.
messages: Membrane

219594:HCN1
gene id: 219594:HCN1
uniprot id: A0A6J3EK52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the potassium channel HCN family.
messages: Cell membrane
messages: Membrane

219594:SLC4A4
gene id: 219594:SLC4A4
uniprot id: A0A6J3CTH0
uniprot id: A0A6J3CVS9
uniprot id: A0A6J3CW81
uniprot id: A0A6J3CYJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anion exchanger (TC 2.A.31) family.
messages: Membrane

219594:LOC116492935
gene id: 219594:LOC116492935
uniprot id: A0A6J3DH48
names: Similarity
messages: Belongs to the CDC50/LEM3 family.

219594:MRPS14
gene id: 219594:MRPS14
uniprot id: A0A6J3DF77
names: Similarity
messages: Belongs to the universal ribosomal protein uS14 family.

219594:LOC116500334
gene id: 219594:LOC116500334
uniprot id: A0A6J3EIE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:DIAPH2
gene id: 219594:DIAPH2
uniprot id: A0A6J3DMQ2
uniprot id: A0A6J3DPH6
uniprot id: A0A6J3DQP5
uniprot id: A0A6J3DRF7
names: Similarity
messages: Belongs to the formin homology family. Diaphanous subfamily.

219594:BCL7A
gene id: 219594:BCL7A
uniprot id: A0A6J3DWK4
names: Similarity
messages: Belongs to the BCL7 family.

219594:LOC116493443
gene id: 219594:LOC116493443
uniprot id: A0A6J3DJL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MOZART2 family.
messages: centrosome
messages: spindle

219594:PA2G4
gene id: 219594:PA2G4
uniprot id: A0A6J3EF39
names: Similarity
messages: Belongs to the peptidase M24 family.

219594:FERMT1
gene id: 219594:FERMT1
uniprot id: A0A6J3CX92
names: Similarity
messages: Belongs to the kindlin family.

219594:EAF1
gene id: 219594:EAF1
uniprot id: A0A6J3CI66
names: Similarity
messages: Belongs to the EAF family.

219594:ZIC1
gene id: 219594:ZIC1
uniprot id: A0A6J3DJ80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GLI C2H2-type zinc-finger protein family.
messages: Nucleus

219594:MGRN1
gene id: 219594:MGRN1
uniprot id: A0A6J3DUV6
uniprot id: A0A6J3DVQ3
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: E3 ubiquitin ligase.

219594:APH1A
gene id: 219594:APH1A
uniprot id: A0A6J3EEB0
uniprot id: A0A6J3EEP1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the APH-1 family.
messages: Component of the gamma-secretase complex.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Potential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral proteins such as Notch receptors.

219594:LOC116494123
gene id: 219594:LOC116494123
uniprot id: A0A6J3DMB2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

219594:LOC116501326
gene id: 219594:LOC116501326
uniprot id: A0A6J3EMW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:MSRB3
gene id: 219594:MSRB3
uniprot id: A0A6J3EN60
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Binds 1 zinc ion per subunit.
messages: Methionine-sulfoxide reductase that specifically reduces methionine (R)-sulfoxide back to methionine. While in many cases methionine oxidation is the result of random oxidation following oxidative stress, methionine oxidation is also a post-translational modification that takes place on specific residues.

219594:LOC116501413
gene id: 219594:LOC116501413
uniprot id: A0A6J3EI10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:VPS26B
gene id: 219594:VPS26B
uniprot id: A0A6J3E6P4
names: Similarity
messages: Belongs to the VPS26 family.

219594:ATP5F1A
gene id: 219594:ATP5F1A
uniprot id: A0A6J3EKW2
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

219594:LHFPL2
gene id: 219594:LHFPL2
uniprot id: A0A6J3EDR0
names: Subcellular Location Annotation
messages: Membrane

219594:RPS6KA1
gene id: 219594:RPS6KA1
uniprot id: A0A6J3E3L2
uniprot id: A0A6J3E8K4
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.

219594:LOC116496184
gene id: 219594:LOC116496184
uniprot id: A0A6J3DZA8
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

219594:NR2C2
gene id: 219594:NR2C2
uniprot id: A0A6J3DHJ2
uniprot id: A0A6J3DKZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

219594:LOC116502392
gene id: 219594:LOC116502392
uniprot id: A0A6J3EQM1
names: Caution
names: Function
names: Subunit
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Non-covalent dimer of an alpha and a beta subunit. IL2R exists in 3 different forms: a high affinity dimer, an intermediate affinity monomer (beta subunit), and a low affinity monomer (alpha subunit). The high and intermediate affinity forms also associate with a gamma subunit.
messages: Receptor for interleukin-2. The receptor is involved in the regulation of immune tolerance by controlling regulatory T cells (TREGs) activity. TREGs suppress the activation and expansion of autoreactive T-cells.

219594:GASK1A
gene id: 219594:GASK1A
uniprot id: A0A6J3CF69
names: Similarity
messages: Belongs to the GASK family.

219594:ARL5A
gene id: 219594:ARL5A
uniprot id: A0A6J3D9P1
names: Similarity
messages: Belongs to the small GTPase superfamily. Arf family.

219594:CEP76
gene id: 219594:CEP76
uniprot id: A0A6J3CR29
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CEP76 family.
messages: Centrosomal protein involved in regulation of centriole duplication. Required to limit centriole duplication to once per cell cycle by preventing centriole reduplication.
messages: centriole

219594:LOC116498076
gene id: 219594:LOC116498076
uniprot id: A0A6J3EA19
names: Subcellular Location Annotation
messages: Membrane

219594:SNX5
gene id: 219594:SNX5
uniprot id: A0A6J3CT36
names: Function
names: Similarity
messages: Belongs to the sorting nexin family.
messages: Involved in several stages of intracellular trafficking.

219594:ACSS2
gene id: 219594:ACSS2
uniprot id: A0A6J3DSZ0
uniprot id: A0A6J3DX65
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

219594:GSKIP
gene id: 219594:GSKIP
uniprot id: A0A6J3D4Z6
names: Similarity
messages: Belongs to the GSKIP family.

219594:CCDC103
gene id: 219594:CCDC103
uniprot id: A0A6J3E6D2
uniprot id: A0A6J3E9D7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CCDC103/PR46b family.
messages: Cytoplasm
messages: Dynein-attachment factor required for cilia motility.
messages: Homodimer.
messages: flagellum

219594:CNOT10
gene id: 219594:CNOT10
uniprot id: A0A6J3CI80
uniprot id: A0A6J3CJN7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CNOT10 family.
messages: Component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation.
messages: Cytoplasm
messages: Nucleus

219594:DCTN2
gene id: 219594:DCTN2
uniprot id: A0A6J3EC51
uniprot id: A0A6J3EHG0
names: Function
names: Similarity
messages: Belongs to the dynactin subunit 2 family.
messages: Modulates cytoplasmic dynein binding to an organelle, and plays a role in prometaphase chromosome alignment and spindle organization during mitosis. Involved in anchoring microtubules to centrosomes. May play a role in synapse formation during brain development.

219594:STOM
gene id: 219594:STOM
uniprot id: A0A6J3E242
names: Similarity
messages: Belongs to the band 7/mec-2 family.

219594:STK11
gene id: 219594:STK11
uniprot id: A0A6J3EDH6
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. LKB1 subfamily.

219594:ASPH
gene id: 219594:ASPH
uniprot id: A0A6J3CC22
uniprot id: A0A6J3CDQ0
uniprot id: A0A6J3CEP8
uniprot id: A0A6J3CEQ3
uniprot id: A0A6J3CGI6
uniprot id: A0A6J3CGJ2
uniprot id: A0A6J3CIC0
uniprot id: A0A6J3CIC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartyl/asparaginyl beta-hydroxylase family.
messages: Membrane

219594:ACTA1
gene id: 219594:ACTA1
uniprot id: A0A6J3CTV5
names: Similarity
messages: Belongs to the actin family.

219594:GRB10
gene id: 219594:GRB10
uniprot id: A0A6J3CLB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GRB7/10/14 family.
messages: Cytoplasm

219594:MKNK2
gene id: 219594:MKNK2
uniprot id: A0A6J3ECM2
names: Similarity
messages: Belongs to the protein kinase superfamily.

219594:ATF7IP
gene id: 219594:ATF7IP
uniprot id: A0A6J3E2U6
uniprot id: A0A6J3E4A6
uniprot id: A0A6J3E7B4
uniprot id: A0A6J3E7R5
uniprot id: A0A6J3E7W9
uniprot id: A0A6J3E7X7
uniprot id: A0A6J3E9A6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCAF family.
messages: Nucleus

219594:PBX4
gene id: 219594:PBX4
uniprot id: A0A6J3EFS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/PBX homeobox family.
messages: Nucleus

219594:LOC116486809
gene id: 219594:LOC116486809
uniprot id: A0A6J3CJN1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:CCDC65
gene id: 219594:CCDC65
uniprot id: A0A6J3EAM8
names: Subcellular Location Annotation
names: Subunit
messages: Component of the nexin-dynein regulatory complex (N-DRC).
messages: flagellum axoneme

219594:ITGA2
gene id: 219594:ITGA2
uniprot id: A0A6J3EHR8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

219594:P4HA2
gene id: 219594:P4HA2
uniprot id: A0A6J3DN80
uniprot id: A0A6J3DN85
uniprot id: A0A6J3DTE0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P4HA family.
messages: Catalyzes the post-translational formation of 4-hydroxyproline in -Xaa-Pro-Gly- sequences in collagens and other proteins.
messages: Endoplasmic reticulum lumen

219594:C17H22orf39
gene id: 219594:C17H22orf39
uniprot id: A0A6J3DZC3
names: Similarity
messages: Belongs to the UPF0545 family.

219594:EIF3B
gene id: 219594:EIF3B
uniprot id: A0A6J3DRW8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit B family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.
messages: Cytoplasm
messages: RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.

219594:SLC12A2
gene id: 219594:SLC12A2
uniprot id: A0A6J3EGP6
uniprot id: A0A6J3ELY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC12A transporter family.
messages: Cell membrane
messages: Membrane

219594:BRMS1L
gene id: 219594:BRMS1L
uniprot id: A0A6J3D6J1
names: Subcellular Location Annotation
messages: Nucleus

219594:LYRM9
gene id: 219594:LYRM9
uniprot id: A0A6J3DYX1
uniprot id: A0A6J3E366
names: Similarity
messages: Belongs to the complex I LYR family. LYRM9 subfamily.

219594:CAV2
gene id: 219594:CAV2
uniprot id: A0A6J3ED70
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the caveolin family.
messages: Cell membrane
messages: Golgi apparatus membrane
messages: May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity.
messages: Membrane
messages: caveola

219594:LOC116500117
gene id: 219594:LOC116500117
uniprot id: A0A6J3ECI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:LOC116501968
gene id: 219594:LOC116501968
uniprot id: A0A6J3ENP5
names: Subcellular Location Annotation
messages: Membrane

219594:LOC116499876
gene id: 219594:LOC116499876
uniprot id: A0A6J3EFC2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

219594:ATRNL1
gene id: 219594:ATRNL1
uniprot id: A0A6J3D5S5
uniprot id: A0A6J3D8H5
uniprot id: A0A6J3D901
uniprot id: A0A6J3DB61
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:NFKB1
gene id: 219594:NFKB1
uniprot id: A0A6J3CU93
uniprot id: A0A6J3CUR9
uniprot id: A0A6J3CX26
uniprot id: A0A6J3CY63
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

219594:TMC3
gene id: 219594:TMC3
uniprot id: A0A6J3DJ60
uniprot id: A0A6J3DM17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMC family.
messages: Membrane

219594:LOC116487964
gene id: 219594:LOC116487964
uniprot id: A0A6J3CW03
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. BTD/VNN family.

219594:SIX6
gene id: 219594:SIX6
uniprot id: A0A6J3D3W6
names: Subcellular Location Annotation
messages: Nucleus

219594:CD79B
gene id: 219594:CD79B
uniprot id: A0A6J3EAE4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

219594:ELOVL6
gene id: 219594:ELOVL6
uniprot id: A0A6J3D1H4
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELO family. ELOVL6 subfamily.
messages: Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that elongates fatty acids with 12, 14 and 16 carbons with higher activity toward C16:0 acyl-CoAs. Catalyzes the synthesis of unsaturated C16 long chain fatty acids and, to a lesser extent, C18:0 and those with low desaturation degree. May participate to the production of saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: N-Glycosylated.

219594:VASN
gene id: 219594:VASN
uniprot id: A0A6J3DVT5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:SLC16A2
gene id: 219594:SLC16A2
uniprot id: A0A6J3DNR0
names: Subcellular Location Annotation
messages: Membrane

219594:GGA1
gene id: 219594:GGA1
uniprot id: A0A6J3DF01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GGA protein family.
messages: Early endosome membrane
messages: Endosome membrane
messages: trans-Golgi network membrane

219594:LOC116498475
gene id: 219594:LOC116498475
uniprot id: A0A6J3E9U1
names: Similarity
names: Subunit
messages: Belongs to the avian keratin family.
messages: The avian keratins (F-ker, S-ker, C-ker and B-ker) are a complex mixture of very similar polypeptides.

219594:SLC44A1
gene id: 219594:SLC44A1
uniprot id: A0A6J3EFI1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CTL (choline transporter-like) family.
messages: Cell membrane
messages: Choline transporter.
messages: Membrane

219594:GALNT12
gene id: 219594:GALNT12
uniprot id: A0A6J3CP46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

219594:RAD9B
gene id: 219594:RAD9B
uniprot id: A0A6J3DVA5
uniprot id: A0A6J3DXI7
uniprot id: A0A6J3DYA8
uniprot id: A0A6J3DZE4
names: Similarity
messages: Belongs to the rad9 family.

219594:CKS2
gene id: 219594:CKS2
uniprot id: A0A6J3EJK6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CKS family.
messages: Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function.
messages: Forms a homohexamer that can probably bind six kinase subunits.

219594:LAMA5
gene id: 219594:LAMA5
uniprot id: A0A6J3DXP1
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: basement membrane

219594:UBE2E3
gene id: 219594:UBE2E3
uniprot id: A0A6J3D9V2
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

219594:TACR1
gene id: 219594:TACR1
uniprot id: A0A6J3EFD0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:SLC7A13
gene id: 219594:SLC7A13
uniprot id: A0A6J3CC93
names: Subcellular Location Annotation
messages: Membrane

219594:LOC116486163
gene id: 219594:LOC116486163
uniprot id: A0A6J3CMK8
names: Similarity
messages: Belongs to the serpin family.

219594:CHST8
gene id: 219594:CHST8
uniprot id: A0A6J3DIQ5
uniprot id: A0A6J3DL88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 2 family.
messages: Golgi apparatus membrane
messages: Membrane

219594:LOC116501196
gene id: 219594:LOC116501196
uniprot id: A0A6J3EMF7
names: Similarity
messages: Belongs to the thioredoxin family.

219594:LOC116498531
gene id: 219594:LOC116498531
uniprot id: A0A6J3E512
names: Similarity
names: Subunit
messages: Belongs to the avian keratin family.
messages: The avian keratins (F-ker, S-ker, C-ker and B-ker) are a complex mixture of very similar polypeptides.

219594:TRAPPC11
gene id: 219594:TRAPPC11
uniprot id: A0A6J3CYQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAPPC11 family.
messages: Involved in endoplasmic reticulum to Golgi apparatus trafficking at a very early stage.
messages: cis-Golgi network

219594:PURG
gene id: 219594:PURG
uniprot id: A0A6J3CZ19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PUR DNA-binding protein family.
messages: Nucleus

219594:OVCH1
gene id: 219594:OVCH1
uniprot id: A0A6J3CLY6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:IL10RB
gene id: 219594:IL10RB
uniprot id: A0A6J3EQU1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tissue factor family.
messages: Initiates blood coagulation by forming a complex with circulating factor VII or VIIa. The [TF:VIIa] complex activates factors IX or X by specific limited proteolysis. TF plays a role in normal hemostasis by initiating the cell-surface assembly and propagation of the coagulation protease cascade.
messages: Interacts with HSPE; the interaction, inhibited by heparin, promotes the generation of activated factor X and activates coagulation in the presence of activated factor VII.

219594:LOC116486660
gene id: 219594:LOC116486660
uniprot id: A0A6J3CKF7
names: Similarity
messages: Belongs to the TMEM14 family.

219594:TK2
gene id: 219594:TK2
uniprot id: A0A6J3DPN6
names: Similarity
messages: Belongs to the DCK/DGK family.

219594:HYOU1
gene id: 219594:HYOU1
uniprot id: A0A6J3E291
names: Similarity
messages: Belongs to the heat shock protein 70 family.

219594:PFKFB2
gene id: 219594:PFKFB2
uniprot id: A0A6J3E6E1
uniprot id: A0A6J3EAW6
uniprot id: A0A6J3EBG6
names: Similarity
names: Subunit
messages: Homodimer.
messages: In the C-terminal section; belongs to the phosphoglycerate mutase family.

219594:VWA1
gene id: 219594:VWA1
uniprot id: A0A6J3E5R1
names: Subcellular Location Annotation
messages: Membrane
messages: basement membrane

219594:MAP3K6
gene id: 219594:MAP3K6
uniprot id: A0A6J3E3Z6
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.

219594:PKIA
gene id: 219594:PKIA
uniprot id: A0A6J3CL74
names: Function
names: Similarity
messages: Belongs to the PKI family.
messages: Extremely potent competitive inhibitor of cAMP-dependent protein kinase activity, this protein interacts with the catalytic subunit of the enzyme after the cAMP-induced dissociation of its regulatory chains.

219594:TCTN1
gene id: 219594:TCTN1
uniprot id: A0A6J3DZE6
names: Similarity
names: Subunit
messages: Belongs to the tectonic family.
messages: Part of the tectonic-like complex (also named B9 complex).

219594:TEX10
gene id: 219594:TEX10
uniprot id: A0A6J3CIP9
uniprot id: A0A6J3CKD3
names: Similarity
messages: Belongs to the IPI1/TEX10 family.

219594:NBN
gene id: 219594:NBN
uniprot id: A0A6J3CP87
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Component of the MRE11-RAD50-NBN (MRN complex) which plays a critical role in the cellular response to DNA damage and the maintenance of chromosome integrity. The complex is involved in double-strand break (DSB) repair, DNA recombination, maintenance of telomere integrity, cell cycle checkpoint control and meiosis.
messages: Component of the MRN complex.
messages: Nucleus
messages: telomere

219594:LOC116499313
gene id: 219594:LOC116499313
uniprot id: A0A6J3E877
names: Similarity
messages: Belongs to the peptidase C14A family.

219594:KCNMA1
gene id: 219594:KCNMA1
uniprot id: A0A6J3D7G0
uniprot id: A0A6J3D7H1
uniprot id: A0A6J3D7I0
uniprot id: A0A6J3D7I5
uniprot id: A0A6J3DA55
uniprot id: A0A6J3DA60
uniprot id: A0A6J3DA64
uniprot id: A0A6J3DA69
uniprot id: A0A6J3DA74
uniprot id: A0A6J3DA79
uniprot id: A0A6J3DAV7
uniprot id: A0A6J3DAW2
uniprot id: A0A6J3DAW7
uniprot id: A0A6J3DAX0
uniprot id: A0A6J3DAX5
uniprot id: A0A6J3DD08
uniprot id: A0A6J3DD16
uniprot id: A0A6J3DD21
uniprot id: A0A6J3DD26
uniprot id: A0A6J3DD31
uniprot id: A0A6J3DD37
uniprot id: A0A6J3DD43
uniprot id: A0A6J3DDE2
uniprot id: A0A6J3DDE7
uniprot id: A0A6J3DDF7
uniprot id: A0A6J3DDG2
uniprot id: A0A6J3DDG7
uniprot id: A0A6J3DDH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the potassium channel family. Calcium-activated (TC 1.A.1.3) subfamily. KCa1.1/KCNMA1 sub-subfamily.
messages: Membrane

219594:ECE1
gene id: 219594:ECE1
uniprot id: A0A6J3E1N3
uniprot id: A0A6J3E2Z9
uniprot id: A0A6J3E7W7
names: Function
messages: Converts big endothelin-1 to endothelin-1.

219594:OTOP3
gene id: 219594:OTOP3
uniprot id: A0A6J3E1E7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the otopetrin family.
messages: Cell membrane
messages: Membrane

219594:ANTXRL
gene id: 219594:ANTXRL
uniprot id: A0A6J3DBL8
uniprot id: A0A6J3DC27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATR family.
messages: Membrane

219594:RPS23
gene id: 219594:RPS23
uniprot id: A0A6J3EK79
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Component of the 40S small ribosomal subunit.
messages: Rough endoplasmic reticulum

219594:CAMK2N1
gene id: 219594:CAMK2N1
uniprot id: A0A6J3E2I6
names: Similarity
messages: Belongs to the CAMK2N family.

219594:GOLT1A
gene id: 219594:GOLT1A
uniprot id: A0A6J3EAP1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GOT1 family.
messages: Golgi apparatus membrane
messages: May be involved in fusion of ER-derived transport vesicles with the Golgi complex.
messages: Membrane

219594:LOC116497523
gene id: 219594:LOC116497523
uniprot id: A0A6J3E252
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

219594:SMOC1
gene id: 219594:SMOC1
uniprot id: A0A6J3D2S3
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

219594:AHCYL1
gene id: 219594:AHCYL1
uniprot id: A0A6J3E684
uniprot id: A0A6J3EAR5
names: Cofactor
names: Similarity
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.

219594:TUT7
gene id: 219594:TUT7
uniprot id: A0A6J3ED45
uniprot id: A0A6J3EEG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-B-like family.
messages: Cytoplasm

219594:TCTEX1D4
gene id: 219594:TCTEX1D4
uniprot id: A0A6J3DBB8
names: Similarity
messages: Belongs to the dynein light chain Tctex-type family.

219594:RBP5
gene id: 219594:RBP5
uniprot id: A0A6J3EKJ2
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

219594:SLC16A9
gene id: 219594:SLC16A9
uniprot id: A0A6J3DE62
names: Subcellular Location Annotation
messages: Membrane

219594:TPH1
gene id: 219594:TPH1
uniprot id: A0A6J3D2W3
names: Similarity
messages: Belongs to the biopterin-dependent aromatic amino acid hydroxylase family.

219594:EXOSC3
gene id: 219594:EXOSC3
uniprot id: A0A6J3DCZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRP40 family.
messages: Cytoplasm

219594:PAQR8
gene id: 219594:PAQR8
uniprot id: A0A6J3CU84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

219594:PGK1
gene id: 219594:PGK1
uniprot id: A0A6J3DL55
names: Similarity
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Monomer.

219594:WIPI2
gene id: 219594:WIPI2
uniprot id: A0A6J3DR68
uniprot id: A0A6J3DUY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat PROPPIN family.
messages: Preautophagosomal structure membrane

219594:HS3ST3A1
gene id: 219594:HS3ST3A1
uniprot id: A0A6J3DXW5
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

219594:LOC116501307
gene id: 219594:LOC116501307
uniprot id: A0A6J3EG59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:CHPT1
gene id: 219594:CHPT1
uniprot id: A0A6J3CWF2
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

219594:TXNRD1
gene id: 219594:TXNRD1
uniprot id: A0A6J3EP04
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

219594:LOC116486605
gene id: 219594:LOC116486605
uniprot id: A0A6J3CLE0
names: Similarity
names: Subunit
messages: Belongs to the avian keratin family.
messages: The avian keratins (F-ker, S-ker, C-ker and B-ker) are a complex mixture of very similar polypeptides.

219594:TBX4
gene id: 219594:TBX4
uniprot id: A0A6J3E6B4
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

219594:SERPINB5
gene id: 219594:SERPINB5
uniprot id: A0A6J3CHK6
names: Similarity
messages: Belongs to the serpin family. Ov-serpin subfamily.

219594:MYLK2
gene id: 219594:MYLK2
uniprot id: A0A6J3DYV6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.
messages: Cytoplasm
messages: May interact with centrin.

219594:ING5
gene id: 219594:ING5
uniprot id: A0A6J3DH87
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ING family.
messages: Component of an histone acetyltransferase complex.
messages: Component of an histone acetyltransferase complex. Interacts with H3K4me3 and to a lesser extent with H3K4me2.
messages: Nucleus
messages: The PHD-type zinc finger mediates the binding to H3K4me3.

219594:MRPL10
gene id: 219594:MRPL10
uniprot id: A0A6J3E4J7
names: Similarity
messages: Belongs to the universal ribosomal protein uL10 family.

219594:EFNA1
gene id: 219594:EFNA1
uniprot id: A0A6J3EFQ5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ephrin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

219594:PELI1
gene id: 219594:PELI1
uniprot id: A0A6J3CS33
uniprot id: A0A6J3CUE0
names: Similarity
messages: Belongs to the pellino family.

219594:PRPF4B
gene id: 219594:PRPF4B
uniprot id: A0A6J3CK30
names: Function
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family.
messages: Has a role in pre-mRNA splicing. Phosphorylates SF2/ASF.

219594:ATP6V1B2
gene id: 219594:ATP6V1B2
uniprot id: A0A6J3E9R7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Apical cell membrane
messages: Belongs to the ATPase alpha/beta chains family.
messages: Non-catalytic subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex. The V1 complex consists of three catalytic AB heterodimers that form a heterohexamer, three peripheral stalks each consisting of EG heterodimers, one central rotor including subunits D and F, and the regulatory subunits C and H. The proton translocation complex V0 consists of the proton transport subunit a, a ring of proteolipid subunits c9c'', rotary subunit d, subunits e and f, and the accessory subunits.

219594:SIX2
gene id: 219594:SIX2
uniprot id: A0A6J3CVH1
names: Subcellular Location Annotation
messages: Nucleus

219594:GRIN2B
gene id: 219594:GRIN2B
uniprot id: A0A6J3EJQ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.
messages: Synaptic cell membrane

219594:FOXI1
gene id: 219594:FOXI1
uniprot id: A0A6J3DTZ8
uniprot id: A0A6J3DUU2
names: Subcellular Location Annotation
messages: Nucleus

219594:SEMA3F
gene id: 219594:SEMA3F
uniprot id: A0A6J3DFI9
uniprot id: A0A6J3DJH4
names: Caution
names: Similarity
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:SLC34A2
gene id: 219594:SLC34A2
uniprot id: A0A6J3D1Q8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the SLC34A transporter family.
messages: Cell membrane
messages: Involved in actively transporting phosphate into cells via Na(+) cotransport.
messages: Membrane

219594:PSMB2
gene id: 219594:PSMB2
uniprot id: A0A6J3E3S1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome complex.
messages: Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
messages: Cytoplasm
messages: Nucleus

219594:ZDHHC14
gene id: 219594:ZDHHC14
uniprot id: A0A6J3CKI0
uniprot id: A0A6J3CM17
uniprot id: A0A6J3CN56
uniprot id: A0A6J3CQD5
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

219594:SEC22C
gene id: 219594:SEC22C
uniprot id: A0A6J3CJT2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Endoplasmic reticulum membrane
messages: May be involved in vesicle transport between the ER and the Golgi complex.
messages: Membrane

219594:DNTT
gene id: 219594:DNTT
uniprot id: A0A6J3DB25
uniprot id: A0A6J3DBX0
uniprot id: A0A6J3DE02
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-X family.
messages: Nucleus
messages: Template-independent DNA polymerase which catalyzes the random addition of deoxynucleoside 5'-triphosphate to the 3'-end of a DNA initiator.

219594:IP6K2
gene id: 219594:IP6K2
uniprot id: A0A6J3DER8
names: Similarity
messages: Belongs to the inositol phosphokinase (IPK) family.

219594:HDGFL2
gene id: 219594:HDGFL2
uniprot id: A0A6J3EEM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HDGF family.
messages: Nucleus

219594:LOC116495709
gene id: 219594:LOC116495709
uniprot id: A0A6J3DWG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

219594:NADSYN1
gene id: 219594:NADSYN1
uniprot id: A0A6J3CZD3
uniprot id: A0A6J3D1X2
uniprot id: A0A6J3D5B3
names: Similarity
names: Subunit
messages: Homohexamer.
messages: In the C-terminal section; belongs to the NAD synthetase family.

219594:SMAD9
gene id: 219594:SMAD9
uniprot id: A0A6J3CXN0
uniprot id: A0A6J3CY07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dwarfin/SMAD family.
messages: Cytoplasm
messages: Nucleus

219594:LOC116488292
gene id: 219594:LOC116488292
uniprot id: A0A6J3CRE6
names: Similarity
messages: Belongs to the cytochrome P450 family.

219594:HMGCS2
gene id: 219594:HMGCS2
uniprot id: A0A6J3DD29
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. HMG-CoA synthase family.
messages: Catalyzes the condensation of acetyl-CoA with acetoacetyl-CoA to form HMG-CoA.

219594:GJA8
gene id: 219594:GJA8
uniprot id: A0A6J3EN36
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family. Alpha-type (group II) subfamily.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

219594:LOC116489498
gene id: 219594:LOC116489498
uniprot id: A0A6J3D039
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:FUT6
gene id: 219594:FUT6
uniprot id: A0A6J3E7U4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 10 family.
messages: Golgi stack membrane

219594:IMPA2
gene id: 219594:IMPA2
uniprot id: A0A6J3CIX9
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

219594:CHRM2
gene id: 219594:CHRM2
uniprot id: A0A6J3EJ42
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Muscarinic acetylcholine receptor subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane
messages: The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins.

219594:GTF2IRD1
gene id: 219594:GTF2IRD1
uniprot id: A0A6J3E079
uniprot id: A0A6J3E1M3
uniprot id: A0A6J3E4E2
uniprot id: A0A6J3E588
uniprot id: A0A6J3E6A4
names: Subcellular Location Annotation
messages: Nucleus

219594:MOGS
gene id: 219594:MOGS
uniprot id: A0A6J3CWK0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 63 family.
messages: Cleaves the distal alpha 1,2-linked glucose residue from the Glc(3)Man(9)GlcNAc(2) oligosaccharide precursor.
messages: Endoplasmic reticulum membrane

219594:SLC25A22
gene id: 219594:SLC25A22
uniprot id: A0A6J3D174
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

219594:LOC116485659
gene id: 219594:LOC116485659
uniprot id: A0A6J3CF37
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

219594:GABRA1
gene id: 219594:GABRA1
uniprot id: A0A6J3DNT0
uniprot id: A0A6J3DU09
uniprot id: A0A6J3DUV3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family. Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily. GABRA1 sub-subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

219594:SENP2
gene id: 219594:SENP2
uniprot id: A0A6J3DFZ0
names: Similarity
messages: Belongs to the peptidase C48 family.

219594:LRRC8D
gene id: 219594:LRRC8D
uniprot id: A0A6J3D984
uniprot id: A0A6J3DF37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LRRC8 family.
messages: Cell membrane
messages: Membrane

219594:ELF1
gene id: 219594:ELF1
uniprot id: A0A6J3EHS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

219594:CRYAA
gene id: 219594:CRYAA
uniprot id: A0A6J3E9K5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small heat shock protein (HSP20) family.
messages: Contributes to the transparency and refractive index of the lens. May act as a chaperone, preventing aggregation of various proteins under a wide range of stress conditions.
messages: Cytoplasm

219594:TM6SF1
gene id: 219594:TM6SF1
uniprot id: A0A6J3DHP8
uniprot id: A0A6J3DKA4
uniprot id: A0A6J3DLT0
uniprot id: A0A6J3DN65
uniprot id: A0A6J3DNU2
names: Subcellular Location Annotation
messages: Membrane

219594:TRIM3
gene id: 219594:TRIM3
uniprot id: A0A6J3E469
uniprot id: A0A6J3E8H4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRIM/RBCC family.
messages: Cytoplasm

219594:GPR107
gene id: 219594:GPR107
uniprot id: A0A6J3E375
names: Subcellular Location Annotation
messages: Membrane

219594:DPY19L3
gene id: 219594:DPY19L3
uniprot id: A0A6J3DPK1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dpy-19 family.
messages: Membrane
messages: Probable C-mannosyltransferase that mediates C-mannosylation of tryptophan residues on target proteins.

219594:VEZT
gene id: 219594:VEZT
uniprot id: A0A6J3CEB4
uniprot id: A0A6J3CGE8
uniprot id: A0A6J3CGN8
uniprot id: A0A6J3CJS1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vezatin family.
messages: Cell membrane
messages: Membrane
messages: Nucleus
messages: adherens junction

219594:PMS1
gene id: 219594:PMS1
uniprot id: A0A6J3D6T9
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.

219594:SPATS2L
gene id: 219594:SPATS2L
uniprot id: A0A6J3D350
uniprot id: A0A6J3D876
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPATS2 family.
messages: Cytoplasm

219594:ACVR2B
gene id: 219594:ACVR2B
uniprot id: A0A6J3CGH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Membrane

219594:CAMKMT
gene id: 219594:CAMKMT
uniprot id: A0A6J3CSM7
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

219594:TCN2
gene id: 219594:TCN2
uniprot id: A0A6J3DZ00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic cobalamin transport proteins family.
messages: Secreted

219594:MEF2C
gene id: 219594:MEF2C
uniprot id: A0A6J3ECA6
uniprot id: A0A6J3EDM6
uniprot id: A0A6J3EH36
uniprot id: A0A6J3EH40
uniprot id: A0A6J3EHC4
uniprot id: A0A6J3EJ07
names: Subcellular Location Annotation
messages: Nucleus

219594:OLA1
gene id: 219594:OLA1
uniprot id: A0A6J3D379
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.
messages: Cytoplasm
messages: Hydrolyzes ATP, and can also hydrolyze GTP with lower efficiency. Has lower affinity for GTP.
messages: Monomer.
messages: Nucleus
messages: nucleolus

219594:VPS13D
gene id: 219594:VPS13D
uniprot id: A0A6J3E0K4
uniprot id: A0A6J3E1Y7
uniprot id: A0A6J3E5K0
uniprot id: A0A6J3E6N3
names: Similarity
messages: Belongs to the VPS13 family.

219594:NKX6-1
gene id: 219594:NKX6-1
uniprot id: A0A6J3D023
names: Subcellular Location Annotation
messages: Nucleus

219594:RPL7
gene id: 219594:RPL7
uniprot id: A0A6J3CN46
names: Similarity
messages: Belongs to the universal ribosomal protein uL30 family.

219594:CENPV
gene id: 219594:CENPV
uniprot id: A0A6J3DZ37
names: Similarity
messages: Belongs to the Gfa family.

219594:XYLB
gene id: 219594:XYLB
uniprot id: A0A6J3CJW9
uniprot id: A0A6J3CLC6
uniprot id: A0A6J3CPL2
uniprot id: A0A6J3CQV4
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Phosphorylates D-xylulose to produce D-xylulose 5-phosphate, a molecule that may play an important role in the regulation of glucose metabolism and lipogenesis.

219594:COQ5
gene id: 219594:COQ5
uniprot id: A0A6J3E0B5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Component of a multi-subunit COQ enzyme complex, composed of at least COQ3, COQ4, COQ5, COQ6, COQ7 and COQ9.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).
messages: Mitochondrion inner membrane

219594:LOC116491890
gene id: 219594:LOC116491890
uniprot id: A0A6J3DFG2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uricase family.
messages: Catalyzes the oxidation of uric acid to 5-hydroxyisourate, which is further processed to form (S)-allantoin.
messages: Peroxisome

219594:LOC116500325
gene id: 219594:LOC116500325
uniprot id: A0A6J3EGJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:LTBP1
gene id: 219594:LTBP1
uniprot id: A0A6J3CPC3
uniprot id: A0A6J3CRB5
uniprot id: A0A6J3CRZ7
uniprot id: A0A6J3CUB2
uniprot id: A0A6J3CVF6
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

219594:DEF8
gene id: 219594:DEF8
uniprot id: A0A6J3DR54
names: Similarity
messages: Belongs to the DEF8 family.

219594:RHBG
gene id: 219594:RHBG
uniprot id: A0A6J3EFV0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonium transporter (TC 2.A.49) family. Rh subfamily.
messages: Membrane

219594:KRT222
gene id: 219594:KRT222
uniprot id: A0A6J3E5R3
uniprot id: A0A6J3E8Q4
names: Similarity
messages: Belongs to the intermediate filament family.

219594:DHX15
gene id: 219594:DHX15
uniprot id: A0A6J3CUR6
names: Similarity
messages: Belongs to the DEAD box helicase family. DEAH subfamily. DDX15/PRP43 sub-subfamily.

219594:ENPP6
gene id: 219594:ENPP6
uniprot id: A0A6J3CUU8
names: Similarity
messages: Belongs to the nucleotide pyrophosphatase/phosphodiesterase family.

219594:ATG16L1
gene id: 219594:ATG16L1
uniprot id: A0A6J3DEG1
uniprot id: A0A6J3DFM4
uniprot id: A0A6J3DHB9
uniprot id: A0A6J3DHW5
names: Similarity
messages: Belongs to the WD repeat ATG16 family.

219594:MAST2
gene id: 219594:MAST2
uniprot id: A0A6J3DAL0
uniprot id: A0A6J3DAL5
uniprot id: A0A6J3DD70
uniprot id: A0A6J3DD75
uniprot id: A0A6J3DE94
uniprot id: A0A6J3DE99
uniprot id: A0A6J3DGA0
uniprot id: A0A6J3DGA6
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.

219594:AMACR
gene id: 219594:AMACR
uniprot id: A0A6J3ELP4
names: Similarity
messages: Belongs to the CoA-transferase III family.

219594:FGD3
gene id: 219594:FGD3
uniprot id: A0A6J3DES9
uniprot id: A0A6J3DHH6
uniprot id: A0A6J3DIR7
uniprot id: A0A6J3DKD6
uniprot id: A0A6J3DKX8
names: Subcellular Location Annotation
messages: cytoskeleton

219594:LOC116495371
gene id: 219594:LOC116495371
uniprot id: A0A6J3DWI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

219594:HS6ST1
gene id: 219594:HS6ST1
uniprot id: A0A6J3DFW1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 6-O-sulfation enzyme which catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to position 6 of the N-sulfoglucosamine residue (GlcNS) of heparan sulfate.
messages: Belongs to the sulfotransferase 6 family.
messages: Membrane

219594:DDX47
gene id: 219594:DDX47
uniprot id: A0A6J3EQ42
names: Similarity
messages: Belongs to the DEAD box helicase family. DDX47/RRP3 subfamily.

219594:CRYGS
gene id: 219594:CRYGS
uniprot id: A0A6J3DD81
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

219594:CFAP43
gene id: 219594:CFAP43
uniprot id: A0A6J3D9G5
names: Similarity
messages: Belongs to the CFAP43 family.

219594:INIP
gene id: 219594:INIP
uniprot id: A0A6J3EHG1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SOSS-C family.
messages: Component of the SOSS complex, a multiprotein complex that functions downstream of the MRN complex to promote DNA repair and G2/M checkpoint. The SOSS complex associates with single-stranded DNA at DNA lesions and influences diverse endpoints in the cellular DNA damage response including cell-cycle checkpoint activation, recombinational repair and maintenance of genomic stability. Required for efficient homologous recombination-dependent repair of double-strand breaks (DSBs).
messages: Component of the SOSS complex.
messages: Nucleus

219594:SLC16A5
gene id: 219594:SLC16A5
uniprot id: A0A6J3E0B0
names: Subcellular Location Annotation
messages: Membrane

219594:WDFY1
gene id: 219594:WDFY1
uniprot id: A0A6J3DHE2
uniprot id: A0A6J3DHY8
names: Subcellular Location Annotation
messages: Early endosome
messages: Endosome

219594:FBLN2
gene id: 219594:FBLN2
uniprot id: A0A6J3DER5
names: Caution
names: Similarity
messages: Belongs to the fibulin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:SPTLC2
gene id: 219594:SPTLC2
uniprot id: A0A6J3CXE7
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

219594:B4GALT1
gene id: 219594:B4GALT1
uniprot id: A0A6J3EBX2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 7 family.
messages: Golgi apparatus membrane
messages: Membrane
messages: Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids.

219594:LPAR2
gene id: 219594:LPAR2
uniprot id: A0A6J3ECF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Cell surface
messages: Endosome
messages: Membrane

219594:PHF19
gene id: 219594:PHF19
uniprot id: A0A6J3DYD4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Polycomblike family.
messages: Nucleus

219594:GABRB3
gene id: 219594:GABRB3
uniprot id: A0A6J3CSV9
uniprot id: A0A6J3CVN2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

219594:LMNA
gene id: 219594:LMNA
uniprot id: A0A6J3EA24
names: Similarity
messages: Belongs to the intermediate filament family.

219594:CLRN3
gene id: 219594:CLRN3
uniprot id: A0A6J3D844
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the clarin family.
messages: Membrane

219594:JPH3
gene id: 219594:JPH3
uniprot id: A0A6J3DN52
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the junctophilin family.
messages: Cell membrane
messages: Endoplasmic reticulum membrane
messages: Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels.
messages: Membrane

219594:CHSY1
gene id: 219594:CHSY1
uniprot id: A0A6J3DKN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chondroitin N-acetylgalactosaminyltransferase family.
messages: Golgi stack membrane
messages: Membrane

219594:FAM234B
gene id: 219594:FAM234B
uniprot id: A0A6J3D777
names: Similarity
messages: Belongs to the FAM234 family.

219594:GRIN3A
gene id: 219594:GRIN3A
uniprot id: A0A6J3EEX8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

219594:GPR171
gene id: 219594:GPR171
uniprot id: A0A6J3DBS4
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

219594:CDK9
gene id: 219594:CDK9
uniprot id: A0A6J3DZQ1
names: Similarity
messages: Belongs to the protein kinase superfamily.

219594:LOC116499874
gene id: 219594:LOC116499874
uniprot id: A0A6J3EF02
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

219594:TEAD3
gene id: 219594:TEAD3
uniprot id: A0A6J3E7H7
uniprot id: A0A6J3ECQ2
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis.

219594:LOC116494397
gene id: 219594:LOC116494397
uniprot id: A0A6J3DRD0
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel CLIC family.
messages: Cytoplasm
messages: Members of this family may change from a globular, soluble state to a state where the N-terminal domain is inserted into the membrane and functions as chloride channel. A conformation change of the N-terminal domain is thought to expose hydrophobic surfaces that trigger membrane insertion.
messages: Membrane

219594:RETREG1
gene id: 219594:RETREG1
uniprot id: A0A6J3CFY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RETREG family.
messages: Membrane

219594:ITGB1
gene id: 219594:ITGB1
uniprot id: A0A6J3CCL3
uniprot id: A0A6J3CE86
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin beta chain family.
messages: Cell membrane
messages: Melanosome
messages: Membrane
messages: invadopodium membrane
messages: lamellipodium
messages: ruffle membrane

219594:TMEM41B
gene id: 219594:TMEM41B
uniprot id: A0A6J3D1K3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM41 family.
messages: Membrane

219594:CTPS2
gene id: 219594:CTPS2
uniprot id: A0A6J3EGW1
uniprot id: A0A6J3EM59
names: Function
names: Similarity
messages: Belongs to the CTP synthase family.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.

219594:DCBLD2
gene id: 219594:DCBLD2
uniprot id: A0A6J3CH43
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:INPP1
gene id: 219594:INPP1
uniprot id: A0A6J3EBX1
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

219594:CA5A
gene id: 219594:CA5A
uniprot id: A0A6J3DJ26
uniprot id: A0A6J3DN87
uniprot id: A0A6J3DPH5
names: Function
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

219594:TMEM59
gene id: 219594:TMEM59
uniprot id: A0A6J3DCI7
uniprot id: A0A6J3DFL5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM59 family.
messages: Golgi apparatus membrane
messages: Membrane

219594:LOC116494911
gene id: 219594:LOC116494911
uniprot id: A0A6J3DTF0
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain.

219594:TRMT1L
gene id: 219594:TRMT1L
uniprot id: A0A6J3DBD7
uniprot id: A0A6J3DEA7
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family.
messages: May play a role in motor coordination and exploratory behavior.

219594:STK35
gene id: 219594:STK35
uniprot id: A0A6J3DY40
names: Similarity
messages: Belongs to the protein kinase superfamily.

219594:NFIB
gene id: 219594:NFIB
uniprot id: A0A6J3EDZ8
uniprot id: A0A6J3EFE2
uniprot id: A0A6J3EFE7
uniprot id: A0A6J3EIV7
uniprot id: A0A6J3EJ81
uniprot id: A0A6J3EJ83
uniprot id: A0A6J3EKR1
uniprot id: A0A6J3EKR6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CTF/NF-I family.
messages: Binds DNA as a homodimer.
messages: Nucleus
messages: Recognizes and binds the palindromic sequence 5'-TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication.

219594:ATF1
gene id: 219594:ATF1
uniprot id: A0A6J3EAH2
uniprot id: A0A6J3EFK4
uniprot id: A0A6J3EH74
names: Subcellular Location Annotation
messages: Nucleus

219594:SNRPG
gene id: 219594:SNRPG
uniprot id: A0A6J3EFB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP Sm proteins family.
messages: Nucleus

219594:GALM
gene id: 219594:GALM
uniprot id: A0A6J3CTM6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aldose epimerase family.
messages: Monomer.
messages: Mutarotase that catalyzes the interconversion of beta-D-galactose and alpha-D-galactose during galactose metabolism.

219594:EMG1
gene id: 219594:EMG1
uniprot id: A0A6J3EM96
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase NEP1 family.

219594:KCNJ5
gene id: 219594:KCNJ5
uniprot id: A0A6J3E3N8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family. KCNJ5 subfamily.
messages: Membrane

219594:TMEM159
gene id: 219594:TMEM159
uniprot id: A0A6J3DT86
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LDAF1 family.
messages: Endoplasmic reticulum membrane
messages: Lipid droplet
messages: Membrane

219594:SPX
gene id: 219594:SPX
uniprot id: A0A6J3CUT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the spexin family.
messages: Secreted

219594:GJA3
gene id: 219594:GJA3
uniprot id: A0A6J3EIH6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

219594:CTNS
gene id: 219594:CTNS
uniprot id: A0A6J3E3U4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cystinosin family.
messages: Membrane

219594:RPL29
gene id: 219594:RPL29
uniprot id: A0A6J3DKS8
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL29 family.

219594:HAAO
gene id: 219594:HAAO
uniprot id: A0A6J3CR18
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 3-HAO family.
messages: Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

219594:CCNB2
gene id: 219594:CCNB2
uniprot id: A0A6J3DMA4
names: Similarity
messages: Belongs to the cyclin family.

219594:LOC116495988
gene id: 219594:LOC116495988
uniprot id: A0A6J3DYC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Deltex family.
messages: Cytoplasm

219594:WNT5A
gene id: 219594:WNT5A
uniprot id: A0A6J3DFW9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

219594:UBA6
gene id: 219594:UBA6
uniprot id: A0A6J3CU24
names: Similarity
messages: Belongs to the ubiquitin-activating E1 family.

219594:CLTA
gene id: 219594:CLTA
uniprot id: A0A6J3ED89
uniprot id: A0A6J3EIE8
uniprot id: A0A6J3EK31
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the clathrin light chain family.
messages: Clathrin is the major protein of the polyhedral coat of coated pits and vesicles.
messages: Cytoplasmic vesicle membrane
messages: coated pit

219594:SHH
gene id: 219594:SHH
uniprot id: A0A6J3CKI1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the hedgehog family.
messages: Cell membrane
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Membrane
messages: Multimer.
messages: The C-terminal part of the hedgehog protein precursor displays an autoproteolysis activity that results in the cleavage of the full-length protein into two parts (N-product and C-product). In addition, the C-terminal part displays a cholesterol transferase activity that results by the covalent attachment of a cholesterol moiety to the C-terminal of the newly generated N-product.
messages: The dually lipidated hedgehog protein N-product is a morphogen which is essential for a variety of patterning events during development.

219594:CITED2
gene id: 219594:CITED2
uniprot id: A0A6J3CUG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CITED family.
messages: Nucleus

219594:ODF2
gene id: 219594:ODF2
uniprot id: A0A6J3DZQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ODF2 family.
messages: centrosome

219594:SLC17A6
gene id: 219594:SLC17A6
uniprot id: A0A6J3D4C1
names: Subcellular Location Annotation
messages: Membrane

219594:GHRH
gene id: 219594:GHRH
uniprot id: A0A6J3DTF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glucagon family.
messages: Secreted

219594:AMIGO3
gene id: 219594:AMIGO3
uniprot id: A0A6J3DHB8
names: Similarity
messages: Belongs to the immunoglobulin superfamily. AMIGO family.

219594:PTK2
gene id: 219594:PTK2
uniprot id: A0A6J3CCL8
uniprot id: A0A6J3CE90
uniprot id: A0A6J3CF89
uniprot id: A0A6J3CFA3
uniprot id: A0A6J3CH37
uniprot id: A0A6J3CH42
uniprot id: A0A6J3CH53
uniprot id: A0A6J3CIV8
uniprot id: A0A6J3CIW3
uniprot id: A0A6J3CIW8
names: Subcellular Location Annotation
messages: Cell membrane
messages: focal adhesion

219594:DCLRE1C
gene id: 219594:DCLRE1C
uniprot id: A0A6J3EKS3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA repair metallo-beta-lactamase (DRMBL) family.
messages: Nucleus

219594:GNG12
gene id: 219594:GNG12
uniprot id: A0A6J3DDB4
uniprot id: A0A6J3DGI6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G protein gamma family.
messages: Cell membrane
messages: G proteins are composed of 3 units; alpha, beta and gamma.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

219594:DRD1
gene id: 219594:DRD1
uniprot id: A0A6J3DSJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:PRUNE2
gene id: 219594:PRUNE2
uniprot id: A0A6J3EC02
uniprot id: A0A6J3EIM0
names: Similarity
messages: Belongs to the PPase class C family. Prune subfamily.

219594:ORAI2
gene id: 219594:ORAI2
uniprot id: A0A6J3E028
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Orai family.
messages: Membrane

219594:HINT1
gene id: 219594:HINT1
uniprot id: A0A6J3EKS2
names: Similarity
messages: Belongs to the HINT family.

219594:MRPL51
gene id: 219594:MRPL51
uniprot id: A0A6J3EN06
names: Similarity
messages: Belongs to the mitochondrion-specific ribosomal protein mL51 family.

219594:GPBP1
gene id: 219594:GPBP1
uniprot id: A0A6J3EDK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vasculin family.
messages: Nucleus

219594:RFC5
gene id: 219594:RFC5
uniprot id: A0A6J3DTF5
names: Similarity
messages: Belongs to the activator 1 small subunits family.

219594:TRAPPC9
gene id: 219594:TRAPPC9
uniprot id: A0A6J3CH08
uniprot id: A0A6J3CIS5
names: Similarity
messages: Belongs to the NIBP family.

219594:MINDY2
gene id: 219594:MINDY2
uniprot id: A0A6J3DJD0
uniprot id: A0A6J3DMT6
names: Function
names: Similarity
messages: Belongs to the MINDY deubiquitinase family. FAM63 subfamily.
messages: Hydrolase that can specifically remove 'Lys-48'-linked conjugated ubiquitin from proteins. Has exodeubiquitinase activity and has a preference for long polyubiquitin chains. May play a regulatory role at the level of protein turnover.

219594:MRPL40
gene id: 219594:MRPL40
uniprot id: A0A6J3DX14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL40 family.
messages: Mitochondrion

219594:LOC116491929
gene id: 219594:LOC116491929
uniprot id: A0A6J3DCF3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:CLDN10
gene id: 219594:CLDN10
uniprot id: A0A6J3DZM6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

219594:SPTBN5
gene id: 219594:SPTBN5
uniprot id: A0A6J3D504
names: Similarity
messages: Belongs to the spectrin family.

219594:LOC116493083
gene id: 219594:LOC116493083
uniprot id: A0A6J3DF56
names: Function
names: Similarity
names: Subunit
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. Pelle subfamily.
messages: Binds to the IL-1 type I receptor following IL-1 engagement, triggering intracellular signaling cascades leading to transcriptional up-regulation and mRNA stabilization.
messages: Interacts with MYD88. IL-1 stimulation leads to the formation of a signaling complex which dissociates from the IL-1 receptor following the binding of PELI1.

219594:ADORA2B
gene id: 219594:ADORA2B
uniprot id: A0A6J3E173
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.

219594:AADAC
gene id: 219594:AADAC
uniprot id: A0A6J3DED8
uniprot id: A0A6J3DHA0
uniprot id: A0A6J3DHU2
names: Similarity
messages: Belongs to the 'GDXG' lipolytic enzyme family.

219594:LOC116500987
gene id: 219594:LOC116500987
uniprot id: A0A6J3EG90
names: Similarity
messages: Belongs to the peptidase M1 family.

219594:MPEG1
gene id: 219594:MPEG1
uniprot id: A0A6J3D7W7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MPEG1 family.
messages: Cytoplasmic vesicle membrane
messages: Membrane

219594:TM4SF18
gene id: 219594:TM4SF18
uniprot id: A0A6J3DFN3
uniprot id: A0A6J3DGW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L6 tetraspanin family.
messages: Membrane

219594:PPP4R3B
gene id: 219594:PPP4R3B
uniprot id: A0A6J3CK95
uniprot id: A0A6J3CLS1
names: Similarity
messages: Belongs to the SMEK family.

219594:HSPA9
gene id: 219594:HSPA9
uniprot id: A0A6J3DMN8
names: Similarity
messages: Belongs to the heat shock protein 70 family.

219594:PNP
gene id: 219594:PNP
uniprot id: A0A6J3DQ24
names: Function
names: Similarity
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.

219594:SLC6A4
gene id: 219594:SLC6A4
uniprot id: A0A6J3E4C1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A4 subfamily.
messages: Cell membrane
messages: Endomembrane system
messages: Endosome membrane
messages: Membrane
messages: Serotonin transporter whose primary function in the central nervous system involves the regulation of serotonergic signaling via transport of serotonin molecules from the synaptic cleft back into the pre-synaptic terminal for re-utilization. Plays a key role in mediating regulation of the availability of serotonin to other receptors of serotonergic systems. Terminates the action of serotonin and recycles it in a sodium-dependent manner.
messages: Synapse
messages: focal adhesion

219594:PPP6R3
gene id: 219594:PPP6R3
uniprot id: A0A6J3CZF0
uniprot id: A0A6J3CZP2
uniprot id: A0A6J3CZP6
names: Similarity
messages: Belongs to the SAPS family.

219594:PAQR9
gene id: 219594:PAQR9
uniprot id: A0A6J3DE08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

219594:TXNDC5
gene id: 219594:TXNDC5
uniprot id: A0A6J3CD67
uniprot id: A0A6J3CJF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein disulfide isomerase family.
messages: Endoplasmic reticulum lumen

219594:LOC116501268
gene id: 219594:LOC116501268
uniprot id: A0A6J3ELA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta type-B retroviral polymerase family. HERV class-II K(HML-2) pol subfamily.
messages: Nucleus

219594:SNF8
gene id: 219594:SNF8
uniprot id: A0A6J3EAX4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SNF8 family.
messages: Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs.
messages: Component of the endosomal sorting complex required for transport II (ESCRT-II).

219594:RIN2
gene id: 219594:RIN2
uniprot id: A0A6J3CKZ6
uniprot id: A0A6J3CMJ2
uniprot id: A0A6J3CNM7
uniprot id: A0A6J3CNN2
uniprot id: A0A6J3CQV7
uniprot id: A0A6J3CRY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. SLC24A subfamily.
messages: Belongs to the RIN (Ras interaction/interference) family.
messages: Membrane

219594:AOPEP
gene id: 219594:AOPEP
uniprot id: A0A6J3EL03
names: Similarity
messages: Belongs to the peptidase M1 family.

219594:PHOSPHO2
gene id: 219594:PHOSPHO2
uniprot id: A0A6J3D5S3
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. PHOSPHO family.

219594:RAB39A
gene id: 219594:RAB39A
uniprot id: A0A6J3DU95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Cell membrane
messages: Membrane

219594:PKNOX2
gene id: 219594:PKNOX2
uniprot id: A0A6J3E7L4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/MEIS homeobox family.
messages: Nucleus

219594:GANC
gene id: 219594:GANC
uniprot id: A0A6J3D5G6
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

219594:LOC116494981
gene id: 219594:LOC116494981
uniprot id: A0A6J3DQV2
names: Subcellular Location Annotation
messages: Secreted

219594:AXIN1
gene id: 219594:AXIN1
uniprot id: A0A6J3DW39
uniprot id: A0A6J3DX06
names: Subcellular Location Annotation
messages: Cell membrane
messages: Cytoplasm
messages: Membrane
messages: Nucleus

219594:CCNI2
gene id: 219594:CCNI2
uniprot id: A0A6J3DTC4
names: Similarity
messages: Belongs to the cyclin family.

219594:MCM9
gene id: 219594:MCM9
uniprot id: A0A6J3CQW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCM family.
messages: Nucleus

219594:ST6GAL1
gene id: 219594:ST6GAL1
uniprot id: A0A6J3DFG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

219594:SLC25A25
gene id: 219594:SLC25A25
uniprot id: A0A6J3DXL0
uniprot id: A0A6J3DZB4
uniprot id: A0A6J3E1R9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

219594:LOC116492291
gene id: 219594:LOC116492291
uniprot id: A0A6J3DGV9
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

219594:TMPRSS9
gene id: 219594:TMPRSS9
uniprot id: A0A6J3EEB2
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

219594:PRPF4
gene id: 219594:PRPF4
uniprot id: A0A6J3DZ11
names: Subcellular Location Annotation
messages: Nucleus speckle

219594:RORC
gene id: 219594:RORC
uniprot id: A0A6J3EFY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

219594:ILDR1
gene id: 219594:ILDR1
uniprot id: A0A6J3DG10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. LISCH7 family.
messages: Membrane
messages: tight junction

219594:LOC116502354
gene id: 219594:LOC116502354
uniprot id: A0A6J3EK20
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

219594:KCNJ12
gene id: 219594:KCNJ12
uniprot id: A0A6J3DVW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.
messages: Cell membrane
messages: Membrane

219594:C1R
gene id: 219594:C1R
uniprot id: A0A6J3EQY3
names: Caution
names: Function
names: Subunit
messages: C1 is a calcium-dependent trimolecular complex of C1q, C1r and C1s in the molar ration of 1:2:2. C1r is a dimer of identical chains, each of which is activated by cleavage into two chains, A and B, connected by disulfide bonds.
messages: C1r B chain is a serine protease that combines with C1q and C1s to form C1, the first component of the classical pathway of the complement system.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:SPP1
gene id: 219594:SPP1
uniprot id: A0A6J3CU80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the osteopontin family.
messages: Secreted

219594:CKAP2
gene id: 219594:CKAP2
uniprot id: A0A6J3EJM7
uniprot id: A0A6J3ENH6
names: Similarity
messages: Belongs to the CKAP2 family.

219594:LOC116499737
gene id: 219594:LOC116499737
uniprot id: A0A6J3E9U3
names: Similarity
names: Subunit
messages: Belongs to the avian keratin family.
messages: The avian keratins (F-ker, S-ker, C-ker and B-ker) are a complex mixture of very similar polypeptides.

219594:LOC116499892
gene id: 219594:LOC116499892
uniprot id: A0A6J3EBQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone H1/H5 family.
messages: Nucleus

219594:FBXO31
gene id: 219594:FBXO31
uniprot id: A0A6J3DIE6
uniprot id: A0A6J3DNV6
names: Similarity
names: Subunit
messages: Belongs to the FBXO31 family.
messages: Part of a SCF (SKP1-cullin-F-box) protein ligase complex.

219594:LOC116489506
gene id: 219594:LOC116489506
uniprot id: A0A6J3D027
names: Subcellular Location Annotation
messages: Membrane

219594:MARCKS
gene id: 219594:MARCKS
uniprot id: A0A6J3CW43
names: Similarity
messages: Belongs to the MARCKS family.

219594:AP2M1
gene id: 219594:AP2M1
uniprot id: A0A6J3DBW2
uniprot id: A0A6J3DEI0
uniprot id: A0A6J3DFN9
uniprot id: A0A6J3DFP5
uniprot id: A0A6J3DHD8
uniprot id: A0A6J3DHY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adaptor complexes medium subunit family.
messages: Cell membrane
messages: coated pit

219594:PTK2B
gene id: 219594:PTK2B
uniprot id: A0A6J3CQM0
names: Subcellular Location Annotation
messages: Cell membrane
messages: focal adhesion

219594:PPP2CB
gene id: 219594:PPP2CB
uniprot id: A0A6J3CW12
names: Similarity
messages: Belongs to the PPP phosphatase family.

219594:FMC1
gene id: 219594:FMC1
uniprot id: A0A6J3D413
names: Similarity
messages: Belongs to the FMC1 family.

219594:LOC116491939
gene id: 219594:LOC116491939
uniprot id: A0A6J3DDG0
names: Subcellular Location Annotation
messages: Secreted

219594:SHMT2
gene id: 219594:SHMT2
uniprot id: A0A6J3EBT6
names: Function
names: Similarity
messages: Belongs to the SHMT family.
messages: Interconversion of serine and glycine.

219594:LOC116497431
gene id: 219594:LOC116497431
uniprot id: A0A6J3E4K4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

219594:ANXA5
gene id: 219594:ANXA5
uniprot id: A0A6J3CXW0
names: Domain
names: Similarity
messages: A pair of annexin repeats may form one binding site for calcium and phospholipid.
messages: Belongs to the annexin family.

219594:LOC116485621
gene id: 219594:LOC116485621
uniprot id: A0A6J3CG07
names: Similarity
messages: Belongs to the dynein heavy chain family.

219594:TNRC6C
gene id: 219594:TNRC6C
uniprot id: A0A6J3DVD6
uniprot id: A0A6J3DVE2
uniprot id: A0A6J3DX82
uniprot id: A0A6J3DX90
uniprot id: A0A6J3DZJ1
uniprot id: A0A6J3DZJ7
uniprot id: A0A6J3E0A8
uniprot id: A0A6J3E1H2
names: Similarity
messages: Belongs to the GW182 family.

219594:SRSF5
gene id: 219594:SRSF5
uniprot id: A0A6J3D002
uniprot id: A0A6J3D2D1
uniprot id: A0A6J3D4W3
uniprot id: A0A6J3D5V2
names: Similarity
messages: Belongs to the splicing factor SR family.

219594:IL12RB2
gene id: 219594:IL12RB2
uniprot id: A0A6J3D9I8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type I cytokine receptor family. Type 2 subfamily.
messages: Membrane

219594:SLC44A3
gene id: 219594:SLC44A3
uniprot id: A0A6J3DAH1
uniprot id: A0A6J3DD33
uniprot id: A0A6J3DG63
uniprot id: A0A6J3DGA2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CTL (choline transporter-like) family.
messages: Cell membrane
messages: Choline transporter.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

219594:PYM1
gene id: 219594:PYM1
uniprot id: A0A6J3EFL3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pym family.
messages: Cytoplasm
messages: Interacts (via N-terminus) with magoh and rbm8a; the interaction is direct. Associates (eIF2A-like region) with the 40S ribosomal subunit and the 48S preinitiation complex.

219594:LOC116488011
gene id: 219594:LOC116488011
uniprot id: A0A6J3CW70
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily.
messages: Cell membrane
messages: Membrane
messages: Receptor for lutropin-choriogonadotropic hormone. The activity of this receptor is mediated by G proteins which activate adenylate cyclase.

219594:ADORA1
gene id: 219594:ADORA1
uniprot id: A0A6J3E7B1
uniprot id: A0A6J3EAC5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase.

219594:YIPF7
gene id: 219594:YIPF7
uniprot id: A0A6J3D073
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YIP1 family.
messages: Membrane

219594:TMEM126A
gene id: 219594:TMEM126A
uniprot id: A0A6J3DLD5
names: Subcellular Location Annotation
messages: Membrane

219594:NTRK1
gene id: 219594:NTRK1
uniprot id: A0A6J3EGS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. Insulin receptor subfamily.
messages: Membrane

219594:SNX1
gene id: 219594:SNX1
uniprot id: A0A6J3DNE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Membrane
messages: lamellipodium
messages: trans-Golgi network membrane

219594:SLC1A3
gene id: 219594:SLC1A3
uniprot id: A0A6J3EI38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

219594:APOH
gene id: 219594:APOH
uniprot id: A0A6J3DWB7
uniprot id: A0A6J3E1B0
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Binds to various kinds of negatively charged substances such as heparin, phospholipids, and dextran sulfate. May prevent activation of the intrinsic blood coagulation cascade by binding to phospholipids on the surface of damaged cells.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

219594:CLCNKA
gene id: 219594:CLCNKA
uniprot id: A0A6J3E335
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel (TC 2.A.49) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

219594:RNF34
gene id: 219594:RNF34
uniprot id: A0A6J3DWJ8
names: Subcellular Location Annotation
messages: Cell membrane

219594:SRP9
gene id: 219594:SRP9
uniprot id: A0A6J3CPB9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SRP9 family.
messages: Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER). SRP9 together with SRP14 and the Alu portion of the SRP RNA, constitutes the elongation arrest domain of SRP. The complex of SRP9 and SRP14 is required for SRP RNA binding.
messages: Cytoplasm

219594:PDK1
gene id: 219594:PDK1
uniprot id: A0A6J3D7A2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PDK/BCKDK protein kinase family.
messages: Mitochondrion matrix

219594:SH3RF2
gene id: 219594:SH3RF2
uniprot id: A0A6J3DMW1
names: Similarity
messages: Belongs to the SH3RF family.

219594:CGA
gene id: 219594:CGA
uniprot id: A0A6J3CQX3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycoprotein hormones subunit alpha family.
messages: Heterodimer of an alpha and a beta chain.
messages: Secreted

219594:GPRIN3
gene id: 219594:GPRIN3
uniprot id: A0A6J3CV74
names: Function
messages: May be involved in neurite outgrowth.

219594:ARSK
gene id: 219594:ARSK
uniprot id: A0A6J3EK06
names: PTM
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

219594:CSMD2
gene id: 219594:CSMD2
uniprot id: A0A6J3E805
uniprot id: A0A6J3E9E9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:ATP9B
gene id: 219594:ATP9B
uniprot id: A0A6J3CK04
uniprot id: A0A6J3CQY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

219594:MID1
gene id: 219594:MID1
uniprot id: A0A6J3DH69
names: Function
names: Subcellular Location Annotation
messages: Has E3 ubiquitin ligase activity towards IGBP1, promoting its monoubiquitination, which results in deprotection of the catalytic subunit of protein phosphatase PP2A, and its subsequent degradation by polyubiquitination.
messages: cytoskeleton

219594:SPR
gene id: 219594:SPR
uniprot id: A0A6J3CX33
names: Similarity
messages: Belongs to the sepiapterin reductase family.

219594:ST8SIA4
gene id: 219594:ST8SIA4
uniprot id: A0A6J3EE54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

219594:CSNK2A2
gene id: 219594:CSNK2A2
uniprot id: A0A6J3DNJ0
names: Similarity
messages: Belongs to the protein kinase superfamily.

219594:TRPM2
gene id: 219594:TRPM2
uniprot id: A0A6J3DH73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transient receptor (TC 1.A.4) family. LTrpC subfamily. TRPM2 sub-subfamily.
messages: Cell membrane
messages: Membrane

219594:LOC116497777
gene id: 219594:LOC116497777
uniprot id: A0A6J3E664
names: Subcellular Location Annotation
messages: Secreted

219594:SLF2
gene id: 219594:SLF2
uniprot id: A0A6J3D9N3
names: Similarity
messages: Belongs to the FAM178 family.

219594:ZC3H12A
gene id: 219594:ZC3H12A
uniprot id: A0A6J3E9A1
names: Similarity
messages: Belongs to the ZC3H12 family.

219594:GPR87
gene id: 219594:GPR87
uniprot id: A0A6J3DHA4
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

219594:LOC116485995
gene id: 219594:LOC116485995
uniprot id: A0A6J3CFJ1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium channel (TC 1.A.1.10) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.
messages: Membrane

219594:GPI
gene id: 219594:GPI
uniprot id: A0A6J3DIV8
names: Similarity
messages: Belongs to the GPI family.

219594:LOC116500503
gene id: 219594:LOC116500503
uniprot id: A0A6J3EHG2
names: Function
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

219594:DOCK8
gene id: 219594:DOCK8
uniprot id: A0A6J3EIF3
names: Similarity
messages: Belongs to the DOCK family.

219594:GPRIN2
gene id: 219594:GPRIN2
uniprot id: A0A6J3DCA6
names: Function
messages: May be involved in neurite outgrowth.

219594:ZUP1
gene id: 219594:ZUP1
uniprot id: A0A6J3CU31
names: Similarity
names: Subunit
messages: Belongs to the peptidase C78 family. ZUFSP subfamily.
messages: Interacts with RPA1 and RPA2.

219594:LIF
gene id: 219594:LIF
uniprot id: A0A6J3DY62
names: Function
messages: LIF has the capacity to induce terminal differentiation in leukemic cells. Its activities include the induction of hematopoietic differentiation in normal and myeloid leukemia cells, the induction of neuronal cell differentiation, and the stimulation of acute-phase protein synthesis in hepatocytes.

219594:GRPEL1
gene id: 219594:GRPEL1
uniprot id: A0A6J3CWN3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GrpE family.
messages: Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner.
messages: Mitochondrion matrix

219594:UHRF1
gene id: 219594:UHRF1
uniprot id: A0A6J3E8J8
names: Subcellular Location Annotation
messages: Nucleus

219594:RBM8A
gene id: 219594:RBM8A
uniprot id: A0A6J3EBG4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RBM8A family.
messages: Core component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junctions on mRNAs.
messages: Cytoplasm
messages: Heterodimer with MAGOH. Part of the mRNA splicing-dependent exon junction complex (EJC) complex; the core complex contains CASC3, EIF4A3, MAGOH and RBM8A.
messages: Nucleus
messages: Nucleus speckle

219594:EXT2
gene id: 219594:EXT2
uniprot id: A0A6J3D0T9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 47 family.
messages: Endoplasmic reticulum membrane

219594:ZIC3
gene id: 219594:ZIC3
uniprot id: A0A6J3DSY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GLI C2H2-type zinc-finger protein family.
messages: Nucleus

219594:TBXAS1
gene id: 219594:TBXAS1
uniprot id: A0A6J3EQS9
names: Similarity
messages: Belongs to the cytochrome P450 family.

219594:KCNG1
gene id: 219594:KCNG1
uniprot id: A0A6J3DR74
names: Subcellular Location Annotation
messages: Membrane

219594:PLK2
gene id: 219594:PLK2
uniprot id: A0A6J3EG27
names: Similarity
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDC5/Polo subfamily.

219594:LOC116496131
gene id: 219594:LOC116496131
uniprot id: A0A6J3DU97
uniprot id: A0A6J3DYD3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:TMEM177
gene id: 219594:TMEM177
uniprot id: A0A6J3DB64
names: Function
names: Similarity
messages: Belongs to the TMEM177 family.
messages: Plays a role in the early steps of cytochrome c oxidase subunit II (MT-CO2/COX2) maturation and is required for the stabilization of COX20 and the newly synthesized MT-CO2/COX2 protein.

219594:P2RX1
gene id: 219594:P2RX1
uniprot id: A0A6J3E0A2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the P2X receptor family.
messages: Functional P2XRs are organized as homomeric and heteromeric trimers.
messages: Membrane
messages: Receptor for ATP that acts as a ligand-gated ion channel.

219594:CDR2
gene id: 219594:CDR2
uniprot id: A0A6J3DPE4
uniprot id: A0A6J3DUN3
names: Similarity
messages: Belongs to the CDR2 family.

219594:HSPB7
gene id: 219594:HSPB7
uniprot id: A0A6J3E5W2
uniprot id: A0A6J3E6M6
uniprot id: A0A6J3E7V6
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

219594:CHST13
gene id: 219594:CHST13
uniprot id: A0A6J3DEZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 2 family.
messages: Golgi apparatus membrane
messages: Membrane

219594:PRPH2
gene id: 219594:PRPH2
uniprot id: A0A6J3CRG1
names: Similarity
messages: Belongs to the PRPH2/ROM1 family.

219594:FLNB
gene id: 219594:FLNB
uniprot id: A0A6J3DFK4
uniprot id: A0A6J3DI89
uniprot id: A0A6J3DL52
uniprot id: A0A6J3DLL9
names: Similarity
messages: Belongs to the filamin family.

219594:TIPRL
gene id: 219594:TIPRL
uniprot id: A0A6J3DAD9
names: Similarity
messages: Belongs to the TIP41 family.

219594:NDUFA12
gene id: 219594:NDUFA12
uniprot id: A0A6J3EP51
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFA12 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

219594:LAP3
gene id: 219594:LAP3
uniprot id: A0A6J3CYP1
names: Similarity
names: Subunit
messages: Belongs to the peptidase M17 family.
messages: Homohexamer.

219594:LEF1
gene id: 219594:LEF1
uniprot id: A0A6J3CWG2
uniprot id: A0A6J3CZ08
uniprot id: A0A6J3D195
uniprot id: A0A6J3D2E4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCF/LEF family.
messages: Nucleus

219594:FGR
gene id: 219594:FGR
uniprot id: A0A6J3E4Q8
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

219594:LOC116493005
gene id: 219594:LOC116493005
uniprot id: A0A6J3DIR3
names: Similarity
messages: Belongs to the CAND family.

219594:SLC25A38
gene id: 219594:SLC25A38
uniprot id: A0A6J3CK51
uniprot id: A0A6J3CM04
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family. SLC25A38 subfamily.
messages: Membrane
messages: Mitochondrial glycine transporter that imports glycine into the mitochondrial matrix. Plays an important role in providing glycine for the first enzymatic step in heme biosynthesis, the condensation of glycine with succinyl-CoA to produce 5-aminolevulinate (ALA) in the miochondrial matrix. Required during erythropoiesis.
messages: Mitochondrion inner membrane

219594:LOC116499081
gene id: 219594:LOC116499081
uniprot id: A0A6J3E8V8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily.
messages: Membrane

219594:STX6
gene id: 219594:STX6
uniprot id: A0A6J3DGK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the syntaxin family.
messages: Golgi apparatus membrane

219594:POP4
gene id: 219594:POP4
uniprot id: A0A6J3DRE6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic/archaeal RNase P protein component 1 family.
messages: Component of nuclear RNase P and RNase MRP.
messages: Component of ribonuclease P, a ribonucleoprotein complex that generates mature tRNA molecules by cleaving their 5'-ends.
messages: nucleolus

219594:DENND11
gene id: 219594:DENND11
uniprot id: A0A6J3CP72
names: Similarity
messages: Belongs to the DENND11 family.

219594:CERS3
gene id: 219594:CERS3
uniprot id: A0A6J3DHF0
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Nucleus

219594:C9H3orf70
gene id: 219594:C9H3orf70
uniprot id: A0A6J3DFC4
names: Similarity
messages: Belongs to the UPF0524 family.

219594:CHRNA6
gene id: 219594:CHRNA6
uniprot id: A0A6J3EGC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

219594:NDUFV1
gene id: 219594:NDUFV1
uniprot id: A0A6J3D612
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I 51 kDa subunit family.
messages: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I.
messages: Mitochondrion inner membrane

219594:TMEM116
gene id: 219594:TMEM116
uniprot id: A0A6J3E0D4
names: Subcellular Location Annotation
messages: Membrane

219594:LOC116502369
gene id: 219594:LOC116502369
uniprot id: A0A6J3EK32
names: Similarity
names: Subunit
messages: Belongs to the histone H3 family.
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

219594:THY1
gene id: 219594:THY1
uniprot id: A0A6J3E8L4
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: May play a role in cell-cell or cell-ligand interactions during synaptogenesis and other events in the brain.
messages: Membrane

219594:LPAR3
gene id: 219594:LPAR3
uniprot id: A0A6J3DGH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:CPE
gene id: 219594:CPE
uniprot id: A0A6J3CUH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M14 family.
messages: Membrane
messages: secretory vesicle membrane

219594:DLD
gene id: 219594:DLD
uniprot id: A0A6J3CZC6
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.
messages: acrosome
messages: flagellum

219594:LOC116486782
gene id: 219594:LOC116486782
uniprot id: A0A6J3CQH6
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

219594:SPDEF
gene id: 219594:SPDEF
uniprot id: A0A6J3E880
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

219594:LOC116492525
gene id: 219594:LOC116492525
uniprot id: A0A6J3DI17
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:LOC116487638
gene id: 219594:LOC116487638
uniprot id: A0A6J3CUJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C2 family.
messages: Cell membrane
messages: Cytoplasm
messages: Membrane

219594:PIGW
gene id: 219594:PIGW
uniprot id: A0A6J3DZ99
uniprot id: A0A6J3E3J4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGW family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Probable acetyltransferase, which acetylates the inositol ring of phosphatidylinositol during biosynthesis of GPI-anchor.

219594:LOC116489528
gene id: 219594:LOC116489528
uniprot id: A0A6J3D2M0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:SLC25A15
gene id: 219594:SLC25A15
uniprot id: A0A6J3ENJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

219594:POLR2H
gene id: 219594:POLR2H
uniprot id: A0A6J3DGH2
names: Function
names: Similarity
messages: Belongs to the eukaryotic RPB8 RNA polymerase subunit family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non-coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively.

219594:VDR
gene id: 219594:VDR
uniprot id: A0A6J3EAK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Cytoplasm
messages: Nucleus

219594:SLC18A1
gene id: 219594:SLC18A1
uniprot id: A0A6J3ECX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Vesicular transporter family.
messages: Membrane

219594:PLCZ1
gene id: 219594:PLCZ1
uniprot id: A0A6J3ENG5
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. In vitro, hydrolyzes PtdIns(4,5)P2 in a Ca(2+)-dependent manner. Triggers intracellular Ca(2+) oscillations in oocytes solely during M phase and is involved in inducing oocyte activation and initiating embryonic development up to the blastocyst stage. Is therefore a strong candidate for the egg-activating soluble sperm factor that is transferred from the sperm into the egg cytoplasm following gamete membrane fusion. May exert an inhibitory effect on phospholipase-C-coupled processes that depend on calcium ions and protein kinase C, including CFTR trafficking and function.
messages: perinuclear region

219594:BTC
gene id: 219594:BTC
uniprot id: A0A6J3CW36
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:RORA
gene id: 219594:RORA
uniprot id: A0A6J3DIU3
uniprot id: A0A6J3DK56
uniprot id: A0A6J3DM70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

219594:RDH8
gene id: 219594:RDH8
uniprot id: A0A6J3EFN9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

219594:LOC116501317
gene id: 219594:LOC116501317
uniprot id: A0A6J3ELI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:LOC116494510
gene id: 219594:LOC116494510
uniprot id: A0A6J3DLH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMP-30/CGR1 family.
messages: Cytoplasm

219594:SSTR4
gene id: 219594:SSTR4
uniprot id: A0A6J3CP06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:FAM32A
gene id: 219594:FAM32A
uniprot id: A0A6J3E8M1
names: Similarity
messages: Belongs to the FAM32 family.

219594:LOC116502360
gene id: 219594:LOC116502360
uniprot id: A0A6J3ELI0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

219594:LOC116500317
gene id: 219594:LOC116500317
uniprot id: A0A6J3EGT0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:TOB2
gene id: 219594:TOB2
uniprot id: A0A6J3EJV3
names: Similarity
messages: Belongs to the BTG family.

219594:STN1
gene id: 219594:STN1
uniprot id: A0A6J3DAH9
uniprot id: A0A6J3DCN5
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Component of the CST complex proposed to act as a specialized replication factor promoting DNA replication under conditions of replication stress or natural replication barriers such as the telomere duplex. The CST complex binds single-stranded DNA with high affinity in a sequence-independent manner, while isolated subunits bind DNA with low affinity by themselves. Initially the CST complex has been proposed to protect telomeres from DNA degradation. However, the CST complex has been shown to be involved in several aspects of telomere replication.
messages: Component of the CST complex.
messages: Nucleus
messages: telomere

219594:LOC116487085
gene id: 219594:LOC116487085
uniprot id: A0A6J3CNC6
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL22 family.

219594:IRF7
gene id: 219594:IRF7
uniprot id: A0A6J3D3I5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IRF family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

219594:MYO15A
gene id: 219594:MYO15A
uniprot id: A0A6J3DQE6
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

219594:ARMC9
gene id: 219594:ARMC9
uniprot id: A0A6J3DC21
names: Subcellular Location Annotation
messages: centriole
messages: cilium
messages: cilium basal body

219594:NPFFR2
gene id: 219594:NPFFR2
uniprot id: A0A6J3CY37
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for NPAF (A-18-F-amide) and NPFF (F-8-F-amide) neuropeptides, also known as morphine-modulating peptides. Can also be activated by a variety of naturally occurring or synthetic FMRF-amide like ligands. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.

219594:GALR1
gene id: 219594:GALR1
uniprot id: A0A6J3CGC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

219594:SETDB1
gene id: 219594:SETDB1
uniprot id: A0A6J3E9G2
uniprot id: A0A6J3EAX2
uniprot id: A0A6J3EE62
uniprot id: A0A6J3EE65
uniprot id: A0A6J3EG84
names: Subcellular Location Annotation
messages: Chromosome
messages: Nucleus

219594:EIF3L
gene id: 219594:EIF3L
uniprot id: A0A6J3ECC5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit L family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
messages: Cytoplasm

219594:USP45
gene id: 219594:USP45
uniprot id: A0A6J3CS21
names: Similarity
messages: Belongs to the peptidase C19 family.

219594:TECR
gene id: 219594:TECR
uniprot id: A0A6J3D8E0
uniprot id: A0A6J3DB43
uniprot id: A0A6J3DBZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the steroid 5-alpha reductase family.
messages: Endoplasmic reticulum membrane
messages: Membrane

219594:UBE2L3
gene id: 219594:UBE2L3
uniprot id: A0A6J3DYH9
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

219594:LOC116489297
gene id: 219594:LOC116489297
uniprot id: A0A6J3CZ85
names: Similarity
messages: Belongs to the copper type II ascorbate-dependent monooxygenase family.

219594:USP35
gene id: 219594:USP35
uniprot id: A0A6J3EH71
names: Similarity
messages: Belongs to the peptidase C19 family.

219594:KCNS3
gene id: 219594:KCNS3
uniprot id: A0A6J3CKA4
names: Subcellular Location Annotation
messages: Membrane

219594:MAP3K5
gene id: 219594:MAP3K5
uniprot id: A0A6J3CMU1
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.

219594:MAFF
gene id: 219594:MAFF
uniprot id: A0A6J3DX63
uniprot id: A0A6J3E1C4
names: Similarity
messages: Belongs to the bZIP family. Maf subfamily.

219594:LOC116485591
gene id: 219594:LOC116485591
uniprot id: A0A6J3CJI4
names: Subcellular Location Annotation
messages: Golgi apparatus membrane
messages: Membrane

219594:ANP32A
gene id: 219594:ANP32A
uniprot id: A0A6J3DHL6
uniprot id: A0A6J3DN32
names: Similarity
messages: Belongs to the ANP32 family.

219594:UBALD1
gene id: 219594:UBALD1
uniprot id: A0A6J3DPT6
names: Similarity
messages: Belongs to the UBALD family.

219594:LOC116494601
gene id: 219594:LOC116494601
uniprot id: A0A6J3DS26
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RRM NCBP2 family.
messages: Component of the cap-binding complex (CBC), which binds co-transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense-mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U snRNA and intronless mRNAs export from the nucleus. The CBC complex is essential for a pioneer round of mRNA translation, before steady state translation when the CBC complex is replaced by cytoplasmic cap-binding protein eIF4E. The pioneer round of mRNA translation mediated by the CBC complex plays a central role in nonsense-mediated mRNA decay (NMD), NMD only taking place in mRNAs bound to the CBC complex, but not on eIF4E-bound mRNAs. The CBC complex enhances NMD in mRNAs containing at least one exon-junction complex (EJC), promoting the interaction between upf1 and upf2. The CBC complex is also involved in 'failsafe' NMD, which is independent of the EJC complex, while it does not participate in Staufen-mediated mRNA decay (SMD). During cell proliferation, the CBC complex is also involved in microRNAs (miRNAs) biogenesis via its interaction with srrt/ars2, thereby being required for miRNA-mediated RNA interference. The CBC complex also acts as a negative regulator of parn, thereby acting as an inhibitor of mRNA deadenylation. In the CBC complex, ncbp2/cbp20 recognizes and binds capped RNAs (m7GpppG-capped RNA) but requires ncbp1/cbp80 to stabilize the movement of its N-terminal loop and lock the CBC into a high affinity cap-binding state with the cap structure. The conventional cap-binding complex with NCBP2 binds both small nuclear RNA (snRNA) and messenger (mRNA) and is involved in their export from the nucleus.
messages: Component of the nuclear cap-binding complex (CBC), a heterodimer composed of ncbp1/cbp80 and ncbp2/cbp20 that interacts with m7GpppG-capped RNA.
messages: Nucleus

219594:SLC30A5
gene id: 219594:SLC30A5
uniprot id: A0A6J3EJC3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
messages: Functions as a zinc transporter.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: trans-Golgi network membrane

219594:TARDBP
gene id: 219594:TARDBP
uniprot id: A0A6J3E6F4
names: Subcellular Location Annotation
messages: Nucleus

219594:NDUFB10
gene id: 219594:NDUFB10
uniprot id: A0A6J3DU36
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit that is involved in the functional assembly of the mitochondrial respiratory chain complex I. Complex I has an NADH dehydrogenase activity with ubiquinone as an immediate electron acceptor and mediates the transfer of electrons from NADH to the respiratory chain.
messages: Belongs to the complex I NDUFB10 subunit family.
messages: Mitochondrion inner membrane

219594:CBY2
gene id: 219594:CBY2
uniprot id: A0A6J3ES45
names: Similarity
messages: Belongs to the chibby family. SPERT subfamily.

219594:KATNA1
gene id: 219594:KATNA1
uniprot id: A0A6J3CQ67
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATPase activity is stimulated by microtubules, which promote homooligomerization. ATP-dependent microtubule severing is stimulated by interaction with KATNB1.
messages: Belongs to the AAA ATPase family. Katanin p60 subunit A1 subfamily.
messages: Can homooligomerize into hexameric rings, which may be promoted by interaction with microtubules. Interacts with KATNB1, which may serve as a targeting subunit.
messages: Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation.
messages: Cytoplasm
messages: centrosome
messages: spindle
messages: spindle pole

219594:PPP4R2
gene id: 219594:PPP4R2
uniprot id: A0A6J3DKE3
names: Similarity
messages: Belongs to the PPP4R2 family.

219594:CA8
gene id: 219594:CA8
uniprot id: A0A6J3CMY0
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.

219594:BUD23
gene id: 219594:BUD23
uniprot id: A0A6J3E1W3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. BUD23/WBSCR22 family.
messages: Cytoplasm
messages: Nucleus

219594:TCP11L2
gene id: 219594:TCP11L2
uniprot id: A0A6J3E563
uniprot id: A0A6J3E604
names: Similarity
messages: Belongs to the TCP11 family.

219594:TMEM50B
gene id: 219594:TMEM50B
uniprot id: A0A6J3CVW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0220 family.
messages: Membrane

219594:UBE2T
gene id: 219594:UBE2T
uniprot id: A0A6J3EB52
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

219594:HSF2
gene id: 219594:HSF2
uniprot id: A0A6J3CRC8
uniprot id: A0A6J3CSD7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSF family.
messages: Nucleus

219594:AGO2
gene id: 219594:AGO2
uniprot id: A0A6J3CIX7
uniprot id: A0A6J3CKD4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argonaute family. Ago subfamily.
messages: Component of the RISC loading complex (RLC), or micro-RNA (miRNA) loading complex (miRLC), which is composed of dicer1, ago2 and tarbp2. Note that the trimeric RLC/miRLC is also referred to as RISC.
messages: P-body
messages: Required for RNA-mediated gene silencing (RNAi) by the RNA-induced silencing complex (RISC). The 'minimal RISC' appears to include ago2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the mRNA specifically by ago2. Binding of RISC to a partially complementary mRNA results in silencing through inhibition of translation, and this is independent of endonuclease activity. The inhibition of translational initiation leads to the accumulation of the affected mRNA in cytoplasmic processing bodies (P-bodies), where mRNA degradation may subsequently occur.
messages: The Piwi domain may perform RNA cleavage by a mechanism similar to that of RNase H. However, while RNase H utilizes a triad of Asp-Asp-Glu (DDE) for metal ion coordination, this protein appears to utilize a triad of Asp-Asp-His (DDH).

219594:ZGPAT
gene id: 219594:ZGPAT
uniprot id: A0A6J3DZ02
names: Subcellular Location Annotation
messages: Nucleus

219594:SLC25A43
gene id: 219594:SLC25A43
uniprot id: A0A6J3DPP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

219594:LOC116486738
gene id: 219594:LOC116486738
uniprot id: A0A6J3CJB3
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

219594:NEK9
gene id: 219594:NEK9
uniprot id: A0A6J3D1A2
uniprot id: A0A6J3D1D6
names: Similarity
messages: Belongs to the protein kinase superfamily. NEK Ser/Thr protein kinase family. NIMA subfamily.

219594:EDC3
gene id: 219594:EDC3
uniprot id: A0A6J3DPB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EDC3 family.
messages: P-body

219594:GAL3ST1
gene id: 219594:GAL3ST1
uniprot id: A0A6J3DZ03
names: Similarity
messages: Belongs to the galactose-3-O-sulfotransferase family.

219594:NOX1
gene id: 219594:NOX1
uniprot id: A0A6J3DLL1
uniprot id: A0A6J3DRV1
uniprot id: A0A6J3DSV4
names: Subcellular Location Annotation
messages: Membrane

219594:LOC116499448
gene id: 219594:LOC116499448
uniprot id: A0A6J3EDH9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:ATP6V0A1
gene id: 219594:ATP6V0A1
uniprot id: A0A6J3E5C7
uniprot id: A0A6J3E9T3
uniprot id: A0A6J3E9T7
uniprot id: A0A6J3EAE9
uniprot id: A0A6J3EBX6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase 116 kDa subunit family.
messages: Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.
messages: Membrane

219594:KRT23
gene id: 219594:KRT23
uniprot id: A0A6J3E4S9
names: Similarity
messages: Belongs to the intermediate filament family.

219594:LOC116495989
gene id: 219594:LOC116495989
uniprot id: A0A6J3DYC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Deltex family.
messages: Cytoplasm

219594:HARBI1
gene id: 219594:HARBI1
uniprot id: A0A6J3CY97
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HARBI1 family.
messages: Cytoplasm
messages: Nucleus
messages: Transposase-derived protein that may have nuclease activity (Potential). Does not have transposase activity.

219594:PCOLCE2
gene id: 219594:PCOLCE2
uniprot id: A0A6J3DH55
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

219594:ABLIM3
gene id: 219594:ABLIM3
uniprot id: A0A6J3DNB6
uniprot id: A0A6J3DNC2
uniprot id: A0A6J3DNC6
uniprot id: A0A6J3DQN0
uniprot id: A0A6J3DQN5
uniprot id: A0A6J3DQP0
uniprot id: A0A6J3DSP4
uniprot id: A0A6J3DSP8
uniprot id: A0A6J3DSQ3
uniprot id: A0A6J3DTH6
uniprot id: A0A6J3DTI1
uniprot id: A0A6J3DTI6
uniprot id: A0A6J3DUE1
uniprot id: A0A6J3DUE4
names: Subcellular Location Annotation
messages: Cytoplasm

219594:TMTC4
gene id: 219594:TMTC4
uniprot id: A0A6J3CML4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMTC family.
messages: Endoplasmic reticulum
messages: Membrane

219594:BRS3
gene id: 219594:BRS3
uniprot id: A0A6J3DMR0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Interacts with C6orf89.
messages: Membrane

219594:CREBL2
gene id: 219594:CREBL2
uniprot id: A0A6J3EKA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. ATF subfamily.
messages: Nucleus

219594:TMEM150C
gene id: 219594:TMEM150C
uniprot id: A0A6J3D0K3
names: Subcellular Location Annotation
messages: Membrane

219594:LOC116502368
gene id: 219594:LOC116502368
uniprot id: A0A6J3EK32
names: Similarity
names: Subunit
messages: Belongs to the histone H3 family.
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

219594:MSI2
gene id: 219594:MSI2
uniprot id: A0A6J3DYV7
uniprot id: A0A6J3E0H6
uniprot id: A0A6J3E0I0
uniprot id: A0A6J3E351
uniprot id: A0A6J3E3Y7
uniprot id: A0A6J3E4Z5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Musashi family.
messages: Cytoplasm

219594:KIF23
gene id: 219594:KIF23
uniprot id: A0A6J3DI70
uniprot id: A0A6J3DKS1
uniprot id: A0A6J3DMC1
uniprot id: A0A6J3DNP1
uniprot id: A0A6J3DNP6
uniprot id: A0A6J3DPB3
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

219594:VDAC3
gene id: 219594:VDAC3
uniprot id: A0A6J3ED02
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic mitochondrial porin family.
messages: Forms a channel through the mitochondrial outer membrane that allows diffusion of small hydrophilic molecules.
messages: Interacts with ARMC12 in a TBC1D21-dependent manner.
messages: Mitochondrion outer membrane

219594:FAM83H
gene id: 219594:FAM83H
uniprot id: A0A6J3CM79
names: Similarity
messages: Belongs to the FAM83 family.

219594:CWC15
gene id: 219594:CWC15
uniprot id: A0A6J3EIX7
names: Similarity
messages: Belongs to the CWC15 family.

219594:DNMT3B
gene id: 219594:DNMT3B
uniprot id: A0A6J3DWI7
names: Subcellular Location Annotation
messages: Nucleus

219594:TMEM200A
gene id: 219594:TMEM200A
uniprot id: A0A6J3CQ52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM200 family.
messages: Membrane

219594:POPDC2
gene id: 219594:POPDC2
uniprot id: A0A6J3EII9
uniprot id: A0A6J3ENQ7
names: Similarity
messages: Belongs to the popeye family.

219594:TMEM63B
gene id: 219594:TMEM63B
uniprot id: A0A6J3CLW8
uniprot id: A0A6J3CRU9
uniprot id: A0A6J3CSW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSC1 (TC 1.A.17) family.
messages: Membrane

219594:THBS1
gene id: 219594:THBS1
uniprot id: A0A6J3D2T0
names: Caution
names: Similarity
messages: Belongs to the thrombospondin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:ITPR3
gene id: 219594:ITPR3
uniprot id: A0A6J3E5N5
uniprot id: A0A6J3E740
uniprot id: A0A6J3EAR6
uniprot id: A0A6J3ECA3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the InsP3 receptor family.
messages: Endoplasmic reticulum membrane
messages: Homotetramer.
messages: Membrane
messages: Receptor for inositol 1,4,5-trisphosphate, a second messenger that mediates the release of intracellular calcium.
messages: The receptor contains a calcium channel in its C-terminal extremity. Its large N-terminal cytoplasmic region has the ligand-binding site in the N-terminus and modulatory sites in the middle portion immediately upstream of the channel region.

219594:LOC116493133
gene id: 219594:LOC116493133
uniprot id: A0A6J3DKU8
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family.

219594:MTERF4
gene id: 219594:MTERF4
uniprot id: A0A6J3DIH8
names: Similarity
messages: Belongs to the mTERF family.

219594:KBTBD8
gene id: 219594:KBTBD8
uniprot id: A0A6J3DJD5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KBTBD8 family.
messages: Golgi apparatus
messages: spindle

219594:PAN3
gene id: 219594:PAN3
uniprot id: A0A6J3CEZ5
uniprot id: A0A6J3CGM9
uniprot id: A0A6J3CL70
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the protein kinase superfamily. PAN3 family.
messages: Contains a pseudokinase domain. The protein kinase domain is predicted to be catalytically inactive because some of the residues important for catalytic activity are substituted and it lacks the equivalent of the binding site for a peptide substrate. However, it has retained an ATP-binding site and ATP-binding is required for mRNA degradation, stimulating the activity of the PAN2 nuclease in vitro. The nucleotide-binding site is juxtaposed to the RNase active site of PAN2 in the complex and may actually bind nucleosides of a poly(A) RNA rather than ATP, feeding the poly(A)-tail to the active site of the deadenylase and thus increasing the efficiency with which this distributive enzyme degrades oligo(A) RNAs.
messages: Homodimer. Forms a heterotrimer with a catalytic subunit PAN2 to form the poly(A)-nuclease (PAN) deadenylation complex. Interacts (via PAM-2 motif) with poly(A)-binding protein PABPC1 (via PABC domain), conferring substrate specificity of the enzyme complex. Interacts with the GW182 family proteins TNRC6A, TNRC6B and TNRC6C.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: P-body
messages: Regulatory subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in general and miRNA-mediated mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein (PABP). PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent 5'-3' exonucleolytic degradation by XRN1. PAN3 acts as a positive regulator for PAN activity, recruiting the catalytic subunit PAN2 to mRNA via its interaction with RNA and PABP, and to miRNA targets via its interaction with GW182 family proteins.
messages: The N-terminal zinc finger binds to poly(A) RNA.
messages: The pseudokinase domain, the coiled-coil (CC), and C-terminal knob domain (CK) form a structural unit (PKC) that forms an extensive high-affinity interaction surface for PAN2.

219594:CDH20
gene id: 219594:CDH20
uniprot id: A0A6J3CM64
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane
messages: Membrane

219594:SLC34A1
gene id: 219594:SLC34A1
uniprot id: A0A6J3DSI0
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the SLC34A transporter family.
messages: Cell membrane
messages: Membrane

219594:CREB1
gene id: 219594:CREB1
uniprot id: A0A6J3D6Z8
uniprot id: A0A6J3D9T3
names: Subcellular Location Annotation
messages: Nucleus

219594:LOC116501371
gene id: 219594:LOC116501371
uniprot id: A0A6J3EHT6
uniprot id: A0A6J3ELJ3
uniprot id: A0A6J3EN04
names: Subcellular Location Annotation
messages: Nucleus

219594:LOC116495067
gene id: 219594:LOC116495067
uniprot id: A0A6J3DU34
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the noggin family.
messages: Homodimer.
messages: Secreted

219594:ZHX3
gene id: 219594:ZHX3
uniprot id: A0A6J3DRU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZHX family.
messages: Nucleus

219594:BCAT1
gene id: 219594:BCAT1
uniprot id: A0A6J3D4L4
uniprot id: A0A6J3D4M3
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

219594:ORMDL2
gene id: 219594:ORMDL2
uniprot id: A0A6J3EH51
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ORM family.
messages: Membrane
messages: Negative regulator of sphingolipid synthesis.

219594:ACSF2
gene id: 219594:ACSF2
uniprot id: A0A6J3E157
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

219594:GRK4
gene id: 219594:GRK4
uniprot id: A0A6J3CVL3
uniprot id: A0A6J3CW18
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.

219594:MAPK4
gene id: 219594:MAPK4
uniprot id: A0A6J3EMG6
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.

219594:RNF13
gene id: 219594:RNF13
uniprot id: A0A6J3DFD7
names: Subcellular Location Annotation
messages: Membrane

219594:LOC116497823
gene id: 219594:LOC116497823
uniprot id: A0A6J3E231
names: Similarity
messages: Belongs to the glycosyl hydrolase 35 family.

219594:GIMD1
gene id: 219594:GIMD1
uniprot id: A0A6J3D2I4
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

219594:ACOX2
gene id: 219594:ACOX2
uniprot id: A0A6J3DFQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acyl-CoA oxidase family.
messages: Peroxisome

219594:GNMT
gene id: 219594:GNMT
uniprot id: A0A6J3CVJ9
uniprot id: A0A6J3CWQ1
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Glycine N-methyltransferase family.

219594:ECRG4
gene id: 219594:ECRG4
uniprot id: A0A6J3DVE6
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the augurin family.
messages: Cytoplasm
messages: Membrane
messages: Secreted

219594:EPHA8
gene id: 219594:EPHA8
uniprot id: A0A6J3E2K4
names: Subcellular Location Annotation
messages: Membrane

219594:TMEM87A
gene id: 219594:TMEM87A
uniprot id: A0A6J3D2R8
names: Subcellular Location Annotation
messages: Membrane

219594:NOP14
gene id: 219594:NOP14
uniprot id: A0A6J3D1C4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOP14 family.
messages: Involved in nucleolar processing of pre-18S ribosomal RNA. Has a role in the nuclear export of 40S pre-ribosomal subunit to the cytoplasm.
messages: nucleolus

219594:PSMG1
gene id: 219594:PSMG1
uniprot id: A0A6J3E4J8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PSMG1 family.
messages: Chaperone protein which promotes assembly of the 20S proteasome as part of a heterodimer with psmg2.
messages: Cytoplasm
messages: Forms a heterodimer with psmg2.

219594:MOCS3
gene id: 219594:MOCS3
uniprot id: A0A6J3DWA8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: In the N-terminal section; belongs to the HesA/MoeB/ThiF family. UBA4 subfamily.
messages: Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Also essential during biosynthesis of the molybdenum cofactor. Acts by mediating the C-terminal thiocarboxylation of sulfur carriers URM1 and MOCS2A. Its N-terminus first activates URM1 and MOCS2A as acyl-adenylates (-COAMP), then the persulfide sulfur on the catalytic cysteine is transferred to URM1 and MOCS2A to form thiocarboxylation (-COSH) of their C-terminus. The reaction probably involves hydrogen sulfide that is generated from the persulfide intermediate and that acts as nucleophile towards URM1 and MOCS2A. Subsequently, a transient disulfide bond is formed. Does not use thiosulfate as sulfur donor; NFS1 probably acting as a sulfur donor for thiocarboxylation reactions.

219594:LOC116499741
gene id: 219594:LOC116499741
uniprot id: A0A6J3E9U8
names: Similarity
messages: Belongs to the CD200R family.

219594:LOC116498761
gene id: 219594:LOC116498761
uniprot id: A0A6J3EAD8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
messages: Membrane

219594:TRMT11
gene id: 219594:TRMT11
uniprot id: A0A6J3CRA4
uniprot id: A0A6J3CTL0
names: Function
messages: Catalytic subunit of an S-adenosyl-L-methionine-dependent tRNA methyltransferase complex that mediates the methylation of the guanosine nucleotide at position 10 (m2G10) in tRNAs.

219594:ABI2
gene id: 219594:ABI2
uniprot id: A0A6J3D292
uniprot id: A0A6J3D297
uniprot id: A0A6J3D2A2
uniprot id: A0A6J3D4P6
uniprot id: A0A6J3D4P9
uniprot id: A0A6J3D4Q4
uniprot id: A0A6J3D532
uniprot id: A0A6J3D537
uniprot id: A0A6J3D7A0
uniprot id: A0A6J3D7A5
uniprot id: A0A6J3D851
uniprot id: A0A6J3D856
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABI family.
messages: cytoskeleton
messages: filopodium
messages: lamellipodium

219594:CLK3
gene id: 219594:CLK3
uniprot id: A0A6J3DL25
names: Similarity
messages: Belongs to the protein kinase superfamily.

219594:LIN7A
gene id: 219594:LIN7A
uniprot id: A0A6J3CF39
uniprot id: A0A6J3CJM3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lin-7 family.
messages: Cell junction
messages: Cell membrane
messages: Membrane
messages: Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells.

219594:LOC116486861
gene id: 219594:LOC116486861
uniprot id: A0A6J3CJV9
names: Similarity
names: Subunit
messages: Belongs to the avian keratin family.
messages: The avian keratins (F-ker, S-ker, C-ker and B-ker) are a complex mixture of very similar polypeptides.

219594:RBBP4
gene id: 219594:RBBP4
uniprot id: A0A6J3E9Y5
names: Subcellular Location Annotation
messages: Nucleus

219594:SCARF2
gene id: 219594:SCARF2
uniprot id: A0A6J3E0A0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:ACSL1
gene id: 219594:ACSL1
uniprot id: A0A6J3CUF2
names: Function
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of long-chain fatty acids to their active form acyl-CoAs for both synthesis of cellular lipids, and degradation via beta-oxidation.

219594:NKX2-5
gene id: 219594:NKX2-5
uniprot id: A0A6J3DUT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NK-2 homeobox family.
messages: Nucleus

219594:LOC116491707
gene id: 219594:LOC116491707
uniprot id: A0A6J3DBD2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IAP family.
messages: Cytoplasm
messages: Nucleus

219594:NFASC
gene id: 219594:NFASC
uniprot id: A0A6J3E695
uniprot id: A0A6J3E699
uniprot id: A0A6J3E6A3
uniprot id: A0A6J3E6A8
uniprot id: A0A6J3E6B5
uniprot id: A0A6J3E7T2
uniprot id: A0A6J3E7T7
uniprot id: A0A6J3E7U1
uniprot id: A0A6J3EAS4
uniprot id: A0A6J3EAS9
uniprot id: A0A6J3EAT4
uniprot id: A0A6J3EAT8
uniprot id: A0A6J3EAU3
uniprot id: A0A6J3EBB9
uniprot id: A0A6J3EBC4
uniprot id: A0A6J3EBD0
uniprot id: A0A6J3EBD5
uniprot id: A0A6J3ECY6
uniprot id: A0A6J3ECZ7
uniprot id: A0A6J3ECZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. L1/neurofascin/NgCAM family.
messages: Membrane

219594:ADCY8
gene id: 219594:ADCY8
uniprot id: A0A6J3CJX1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.
messages: Membrane

219594:AP2B1
gene id: 219594:AP2B1
uniprot id: A0A6J3E422
names: Similarity
messages: Belongs to the adaptor complexes large subunit family.

219594:NIPSNAP3A
gene id: 219594:NIPSNAP3A
uniprot id: A0A6J3EKB3
names: Similarity
messages: Belongs to the NipSnap family.

219594:PLD4
gene id: 219594:PLD4
uniprot id: A0A6J3D6T0
names: Similarity
messages: Belongs to the phospholipase D family.

219594:JPT2
gene id: 219594:JPT2
uniprot id: A0A6J3DSP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the JUPITER family.
messages: Cytoplasm
messages: Nucleus

219594:MTX1
gene id: 219594:MTX1
uniprot id: A0A6J3EB23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metaxin family.
messages: Membrane
messages: Mitochondrion outer membrane

219594:ADAMTS6
gene id: 219594:ADAMTS6
uniprot id: A0A6J3EGY1
uniprot id: A0A6J3EM68
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

219594:LOC116496990
gene id: 219594:LOC116496990
uniprot id: A0A6J3E4E5
names: Similarity
messages: Belongs to the calycin superfamily. Lipocalin family.

219594:USP15
gene id: 219594:USP15
uniprot id: A0A6J3CX49
uniprot id: A0A6J3CX56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C19 family.
messages: Cytoplasm
messages: Nucleus

219594:FAM110B
gene id: 219594:FAM110B
uniprot id: A0A6J3CGN4
names: Similarity
messages: Belongs to the FAM110 family.

219594:HMGCL
gene id: 219594:HMGCL
uniprot id: A0A6J3E7M4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HMG-CoA lyase family.
messages: Homodimer; disulfide-linked. Can also form homotetramers.
messages: Mitochondrial 3-hydroxymethyl-3-methylglutaryl-CoA lyase that catalyzes a cation-dependent cleavage of (S)-3-hydroxy-3-methylglutaryl-CoA into acetyl-CoA and acetoacetate, a key step in ketogenesis. Terminal step in leucine catabolism. Ketone bodies (beta-hydroxybutyrate, acetoacetate and acetone) are essential as an alternative source of energy to glucose, as lipid precursors and as regulators of metabolism.

219594:PCNX4
gene id: 219594:PCNX4
uniprot id: A0A6J3D4N3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pecanex family.
messages: Membrane

219594:CALCR
gene id: 219594:CALCR
uniprot id: A0A6J3CP62
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 2 family.
messages: Cell membrane
messages: Interacts with GPRASP2.
messages: Membrane

219594:PPIP5K1
gene id: 219594:PPIP5K1
uniprot id: A0A6J3DG69
uniprot id: A0A6J3DG75
uniprot id: A0A6J3DIV9
uniprot id: A0A6J3DIW4
uniprot id: A0A6J3DK71
uniprot id: A0A6J3DLS2
uniprot id: A0A6J3DM88
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histidine acid phosphatase family. VIP1 subfamily.
messages: Bifunctional inositol kinase that acts in concert with the IP6K kinases to synthesize the diphosphate group-containing inositol pyrophosphates diphosphoinositol pentakisphosphate, PP-InsP5, and bis-diphosphoinositol tetrakisphosphate, (PP)2-InsP4. PP-InsP5 and (PP)2-InsP4, also respectively called InsP7 and InsP8, may regulate a variety of cellular processes, including apoptosis, vesicle trafficking, cytoskeletal dynamics, and exocytosis. Phosphorylates inositol hexakisphosphate (InsP6).
messages: cytosol

219594:LIN9
gene id: 219594:LIN9
uniprot id: A0A6J3CTP6
uniprot id: A0A6J3CWE9
names: Similarity
messages: Belongs to the lin-9 family.

219594:NAV2
gene id: 219594:NAV2
uniprot id: A0A6J3CWR1
uniprot id: A0A6J3CWR6
uniprot id: A0A6J3CYZ8
uniprot id: A0A6J3CZA5
uniprot id: A0A6J3D1J6
uniprot id: A0A6J3D2N6
uniprot id: A0A6J3D2P1
names: Similarity
messages: Belongs to the Nav/unc-53 family.

219594:PRKCA
gene id: 219594:PRKCA
uniprot id: A0A6J3E0I3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Membrane
messages: Mitochondrion membrane
messages: Nucleus

219594:STK32C
gene id: 219594:STK32C
uniprot id: A0A6J3DBM8
names: Similarity
messages: Belongs to the protein kinase superfamily.

219594:ST3GAL2
gene id: 219594:ST3GAL2
uniprot id: A0A6J3DPC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

219594:MRPL50
gene id: 219594:MRPL50
uniprot id: A0A6J3EKV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL50 family.
messages: Mitochondrion

219594:PRKAR2A
gene id: 219594:PRKAR2A
uniprot id: A0A6J3DKG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cAMP-dependent kinase regulatory chain family.
messages: Cell membrane
messages: Membrane

219594:PKP2
gene id: 219594:PKP2
uniprot id: A0A6J3D498
names: Similarity
messages: Belongs to the beta-catenin family.

219594:SLC1A7
gene id: 219594:SLC1A7
uniprot id: A0A6J3DCM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

219594:MTX3
gene id: 219594:MTX3
uniprot id: A0A6J3EK78
uniprot id: A0A6J3ELR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metaxin family.
messages: Membrane
messages: Mitochondrion outer membrane

219594:TBXT
gene id: 219594:TBXT
uniprot id: A0A6J3CPZ3
uniprot id: A0A6J3CS63
uniprot id: A0A6J3CSN7
uniprot id: A0A6J3CW33
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

219594:LOC116486582
gene id: 219594:LOC116486582
uniprot id: A0A6J3CL95
uniprot id: A0A6J3CN66
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

219594:PTP4A1
gene id: 219594:PTP4A1
uniprot id: A0A6J3CN95
names: Subcellular Location Annotation
messages: Early endosome
messages: Endosome

219594:ELAC2
gene id: 219594:ELAC2
uniprot id: A0A6J3E215
names: Similarity
messages: Belongs to the RNase Z family.

219594:LOC116494561
gene id: 219594:LOC116494561
uniprot id: A0A6J3DQY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POU transcription factor family.
messages: Nucleus

219594:LOC116495354
gene id: 219594:LOC116495354
uniprot id: A0A6J3DWG4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

219594:FAM189A1
gene id: 219594:FAM189A1
uniprot id: A0A6J3DMR9
names: Similarity
messages: Belongs to the ENTREP family.

219594:MB
gene id: 219594:MB
uniprot id: A0A6J3EQX3
names: Function
names: Similarity
messages: Belongs to the globin family.
messages: Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles.

219594:GJC1
gene id: 219594:GJC1
uniprot id: A0A6J3E697
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family. Gamma-type subfamily.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

219594:KIF11
gene id: 219594:KIF11
uniprot id: A0A6J3DAP4
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

219594:TSPAN32
gene id: 219594:TSPAN32
uniprot id: A0A6J3CZJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

219594:MFRP
gene id: 219594:MFRP
uniprot id: A0A6J3E969
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:MAS1
gene id: 219594:MAS1
uniprot id: A0A6J3CUC0
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

219594:RSPO3
gene id: 219594:RSPO3
uniprot id: A0A6J3CUT6
names: Similarity
messages: Belongs to the R-spondin family.

219594:S100Z
gene id: 219594:S100Z
uniprot id: A0A6J3EKC2
names: Similarity
messages: Belongs to the S-100 family.

219594:POLR3H
gene id: 219594:POLR3H
uniprot id: A0A6J3DMG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic RPB7/RPC8 RNA polymerase subunit family.
messages: Nucleus

219594:LAPTM4A
gene id: 219594:LAPTM4A
uniprot id: A0A6J3CVI8
names: Similarity
messages: Belongs to the LAPTM4/LAPTM5 transporter family.

219594:ABHD3
gene id: 219594:ABHD3
uniprot id: A0A6J3CEX7
uniprot id: A0A6J3CGR5
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 4 family.

219594:RTCB
gene id: 219594:RTCB
uniprot id: A0A6J3E7U2
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.
messages: Catalytic component of the tRNA-splicing ligase complex.
messages: Catalytic subunit of the tRNA-splicing ligase complex that acts by directly joining spliced tRNA halves to mature-sized tRNAs by incorporating the precursor-derived splice junction phosphate into the mature tRNA as a canonical 3',5'-phosphodiester. May act as an RNA ligase with broad substrate specificity, and may function toward other RNAs.
messages: Cytoplasm
messages: Ligation probably proceeds through 3 nucleotidyl transfer steps, with 2',3'-cyclic phosphate termini being hydrolyzed to 3'-P termini in a step that precedes 3'-P activation with GMP. In the first nucleotidyl transfer step, RTCB reacts with GTP to form a covalent RTCB-histidine-GMP intermediate with release of PPi; in the second step, the GMP moiety is transferred to the RNA 3'-P; in the third step, the 5'-OH from the opposite RNA strand attacks the activated 3'-P to form a 3',5'-phosphodiester bond and release GMP.

219594:CHSY3
gene id: 219594:CHSY3
uniprot id: A0A6J3EGE3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chondroitin N-acetylgalactosaminyltransferase family.
messages: Golgi stack membrane
messages: Membrane

219594:ASIC4
gene id: 219594:ASIC4
uniprot id: A0A6J3D729
uniprot id: A0A6J3D9S6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family.
messages: Membrane

219594:FCHO2
gene id: 219594:FCHO2
uniprot id: A0A6J3EDH3
uniprot id: A0A6J3EGY8
uniprot id: A0A6J3EH72
uniprot id: A0A6J3EIV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FCHO family.
messages: clathrin-coated pit

219594:LOC116487999
gene id: 219594:LOC116487999
uniprot id: A0A6J3CS88
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

219594:SLC37A1
gene id: 219594:SLC37A1
uniprot id: A0A6J3EHU5
uniprot id: A0A6J3EN24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family.
messages: Membrane

219594:CCK
gene id: 219594:CCK
uniprot id: A0A6J3CIG9
uniprot id: A0A6J3CJX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gastrin/cholecystokinin family.
messages: Secreted

219594:BACE1
gene id: 219594:BACE1
uniprot id: A0A6J3E3I6
uniprot id: A0A6J3E8E6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A1 family.
messages: Membrane
messages: Membrane raft
messages: Recycling endosome
messages: trans-Golgi network

219594:FGD4
gene id: 219594:FGD4
uniprot id: A0A6J3EC63
uniprot id: A0A6J3EIV6
names: Subcellular Location Annotation
messages: cytoskeleton

219594:BMPR2
gene id: 219594:BMPR2
uniprot id: A0A6J3D3N6
names: Similarity
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.

219594:GATA2
gene id: 219594:GATA2
uniprot id: A0A6J3DL23
names: Subcellular Location Annotation
messages: Nucleus

219594:SPDYA
gene id: 219594:SPDYA
uniprot id: A0A6J3CQ27
names: Similarity
messages: Belongs to the Speedy/Ringo family.

219594:EXOC3
gene id: 219594:EXOC3
uniprot id: A0A6J3CES7
names: Similarity
messages: Belongs to the SEC6 family.

219594:MYBL1
gene id: 219594:MYBL1
uniprot id: A0A6J3CFZ5
uniprot id: A0A6J3CKJ6
uniprot id: A0A6J3CM89
names: Subcellular Location Annotation
messages: Nucleus

219594:ATF2
gene id: 219594:ATF2
uniprot id: A0A6J3D581
uniprot id: A0A6J3D5J8
uniprot id: A0A6J3D8L3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family.
messages: Nucleus

219594:GALNS
gene id: 219594:GALNS
uniprot id: A0A6J3DNF6
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sulfatase family.
messages: Homodimer.
messages: Lysosome
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

219594:SLBP
gene id: 219594:SLBP
uniprot id: A0A6J3CZH0
names: Similarity
messages: Belongs to the SLBP family.

219594:IPO7
gene id: 219594:IPO7
uniprot id: A0A6J3CZP8
names: Subcellular Location Annotation
messages: Cytoplasm

219594:TMEM129
gene id: 219594:TMEM129
uniprot id: A0A6J3CX52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM129 family.
messages: Membrane

219594:CAMSAP1
gene id: 219594:CAMSAP1
uniprot id: A0A6J3E284
uniprot id: A0A6J3E3C7
names: Domain
names: Similarity
messages: Belongs to the CAMSAP1 family.
messages: The CKK domain binds microtubules.

219594:LOC116492465
gene id: 219594:LOC116492465
uniprot id: A0A6J3DG77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Membrane

219594:CERS6
gene id: 219594:CERS6
uniprot id: A0A6J3D626
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Nucleus

219594:USP24
gene id: 219594:USP24
uniprot id: A0A6J3DEV5
names: Similarity
messages: Belongs to the peptidase C19 family.

219594:TMEM163
gene id: 219594:TMEM163
uniprot id: A0A6J3D2I5
uniprot id: A0A6J3D8E3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM163 family.
messages: Early endosome membrane
messages: Endosome membrane
messages: May bind zinc and other divalent cations and recruit them to vesicular organelles.
messages: Membrane
messages: synaptic vesicle membrane

219594:PROX2
gene id: 219594:PROX2
uniprot id: A0A6J3D305
names: Subcellular Location Annotation
messages: Nucleus

219594:CLN5
gene id: 219594:CLN5
uniprot id: A0A6J3EIR9
names: Similarity
messages: Belongs to the CLN5 family.

219594:LOC116486233
gene id: 219594:LOC116486233
uniprot id: A0A6J3CGS4
uniprot id: A0A6J3CIB4
names: Function
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

219594:MAP4K5
gene id: 219594:MAP4K5
uniprot id: A0A6J3D0N3
uniprot id: A0A6J3D6I0
names: Function
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.
messages: May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway.

219594:RSPO2
gene id: 219594:RSPO2
uniprot id: A0A6J3CMA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the R-spondin family.
messages: Secreted

219594:SDHC
gene id: 219594:SDHC
uniprot id: A0A6J3EFX8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b560 family.
messages: Component of complex II composed of four subunits: the flavoprotein (FP) SDHA, iron-sulfur protein (IP) SDHB, and a cytochrome b560 composed of SDHC and SDHD.
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).

219594:LOC116498656
gene id: 219594:LOC116498656
uniprot id: A0A6J3EC05
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-10 family.
messages: Immune regulatory cytokine.
messages: Secreted

219594:PIGX
gene id: 219594:PIGX
uniprot id: A0A6J3DIS2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGX family.
messages: Endoplasmic reticulum membrane
messages: Essential component of glycosylphosphatidylinositol-mannosyltransferase 1 which transfers the first of the 4 mannoses in the GPI-anchor precursors during GPI-anchor biosynthesis.

219594:SLC39A8
gene id: 219594:SLC39A8
uniprot id: A0A6J3CVC7
names: Subcellular Location Annotation
messages: Membrane

219594:TMEM50A
gene id: 219594:TMEM50A
uniprot id: A0A6J3E4E8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0220 family.
messages: Membrane

219594:HMMR
gene id: 219594:HMMR
uniprot id: A0A6J3DTX0
uniprot id: A0A6J3DUS3
names: Subcellular Location Annotation
messages: spindle

219594:GRHL3
gene id: 219594:GRHL3
uniprot id: A0A6J3E529
names: Subcellular Location Annotation
messages: Nucleus

219594:CDC42EP1
gene id: 219594:CDC42EP1
uniprot id: A0A6J3EN40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BORG/CEP family.
messages: Endomembrane system

219594:PTAR1
gene id: 219594:PTAR1
uniprot id: A0A6J3EKH9
names: Similarity
messages: Belongs to the protein prenyltransferase subunit alpha family.

219594:GAB3
gene id: 219594:GAB3
uniprot id: A0A6J3DNB7
uniprot id: A0A6J3DS72
names: Similarity
messages: Belongs to the GAB family.

219594:SLC35C2
gene id: 219594:SLC35C2
uniprot id: A0A6J3DU48
names: Subcellular Location Annotation
messages: Membrane

219594:NOTCH2
gene id: 219594:NOTCH2
uniprot id: A0A6J3D8L0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOTCH family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Nucleus

219594:ARL4C
gene id: 219594:ARL4C
uniprot id: A0A6J3D4Q6
names: Similarity
messages: Belongs to the small GTPase superfamily. Arf family.

219594:LOC116501424
gene id: 219594:LOC116501424
uniprot id: A0A6J3ELX3
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

219594:OPN3
gene id: 219594:OPN3
uniprot id: A0A6J3CRG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
messages: Membrane

219594:RAN
gene id: 219594:RAN
uniprot id: A0A6J3DU76
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Ran family.
messages: GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle.
messages: Nucleus

219594:DDX52
gene id: 219594:DDX52
uniprot id: A0A6J3E5E4
names: Similarity
messages: Belongs to the DEAD box helicase family. DDX52/ROK1 subfamily.

219594:LOC116492237
gene id: 219594:LOC116492237
uniprot id: A0A6J3DEZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the hcp beta-lactamase family.
messages: Mitochondrion intermembrane space

219594:POLR2B
gene id: 219594:POLR2B
uniprot id: A0A6J3CXF3
uniprot id: A0A6J3CYI3
names: Function
names: Similarity
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.

219594:PDCD5
gene id: 219594:PDCD5
uniprot id: A0A6J3DQ01
names: Similarity
messages: Belongs to the PDCD5 family.

219594:HOMER2
gene id: 219594:HOMER2
uniprot id: A0A6J3DJZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Homer family.
messages: Cytoplasm
messages: Postsynaptic density
messages: Synapse

219594:LOC116493873
gene id: 219594:LOC116493873
uniprot id: A0A6J3DQ10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 1 family. Gal/GlcNAc/GalNAc subfamily.
messages: Membrane

219594:CDC14B
gene id: 219594:CDC14B
uniprot id: A0A6J3ECE2
uniprot id: A0A6J3ECE6
uniprot id: A0A6J3EH80
uniprot id: A0A6J3EHH1
uniprot id: A0A6J3EHH5
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class CDC14 subfamily.

219594:LOC116497430
gene id: 219594:LOC116497430
uniprot id: A0A6J3E1S6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family.
messages: Membrane

219594:VPS13A
gene id: 219594:VPS13A
uniprot id: A0A6J3EFI6
uniprot id: A0A6J3EGZ5
uniprot id: A0A6J3EKQ3
uniprot id: A0A6J3EKT2
uniprot id: A0A6J3EM76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS13 family.
messages: Lipid droplet

219594:FAM20B
gene id: 219594:FAM20B
uniprot id: A0A6J3DFE0
names: Similarity
messages: Belongs to the FAM20 family.

219594:ALG12
gene id: 219594:ALG12
uniprot id: A0A6J3CQU3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Adds the eighth mannose residue in an alpha-1,6 linkage onto the dolichol-PP-oligosaccharide precursor (dolichol-PP-Man(7)GlcNAc(2)) required for protein glycosylation.
messages: Belongs to the glycosyltransferase 22 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

219594:EIF4E
gene id: 219594:EIF4E
uniprot id: A0A6J3CYN0
names: Similarity
messages: Belongs to the eukaryotic initiation factor 4E family.

219594:LOC116487535
gene id: 219594:LOC116487535
uniprot id: A0A6J3CU35
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the noggin family.
messages: Homodimer.
messages: Secreted

219594:PPIL6
gene id: 219594:PPIL6
uniprot id: A0A6J3CPN8
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

219594:LSS
gene id: 219594:LSS
uniprot id: A0A6J3D9E6
names: Similarity
messages: Belongs to the terpene cyclase/mutase family.

219594:GJB3
gene id: 219594:GJB3
uniprot id: A0A6J3E3R1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

219594:GARS1
gene id: 219594:GARS1
uniprot id: A0A6J3CN82
names: Similarity
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Homodimer.

219594:IRAK1BP1
gene id: 219594:IRAK1BP1
uniprot id: A0A6J3CXR8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IRAK1BP1 family.
messages: Cytoplasm
messages: Nucleus

219594:EIF3H
gene id: 219594:EIF3H
uniprot id: A0A6J3CMC0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit H family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
messages: Cytoplasm

219594:XPOT
gene id: 219594:XPOT
uniprot id: A0A6J3DG59
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exportin family.
messages: Cytoplasm
messages: Nucleus
messages: tRNA nucleus export receptor which facilitates tRNA translocation across the nuclear pore complex.

219594:RAB27A
gene id: 219594:RAB27A
uniprot id: A0A6J3DHZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Endosome
messages: Late endosome
messages: Membrane

219594:LOC116496164
gene id: 219594:LOC116496164
uniprot id: A0A6J3DUD0
names: Subcellular Location Annotation
messages: Membrane

219594:GABBR2
gene id: 219594:GABBR2
uniprot id: A0A6J3CCD8
uniprot id: A0A6J3CE14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 3 family. GABA-B receptor subfamily.
messages: Cell membrane
messages: Membrane

219594:TGIF2
gene id: 219594:TGIF2
uniprot id: A0A6J3DUA0
names: Subcellular Location Annotation
messages: Nucleus

219594:LOC116499495
gene id: 219594:LOC116499495
uniprot id: A0A6J3E8V9
uniprot id: A0A6J3EE05
names: Subcellular Location Annotation
messages: Nucleus

219594:LOC116499761
gene id: 219594:LOC116499761
uniprot id: A0A6J3EGN1
names: Similarity
names: Subunit
messages: Belongs to the avian keratin family.
messages: The avian keratins (F-ker, S-ker, C-ker and B-ker) are a complex mixture of very similar polypeptides.

219594:LOC116494779
gene id: 219594:LOC116494779
uniprot id: A0A6J3DS18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:CHMP2A
gene id: 219594:CHMP2A
uniprot id: A0A6J3EBC9
names: Similarity
messages: Belongs to the SNF7 family.

219594:LOC116495454
gene id: 219594:LOC116495454
uniprot id: A0A6J3DT19
names: Similarity
messages: Belongs to the UPF0488 family.

219594:UNC50
gene id: 219594:UNC50
uniprot id: A0A6J3CJA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the unc-50 family.
messages: Membrane
messages: Nucleus inner membrane

219594:VGLL3
gene id: 219594:VGLL3
uniprot id: A0A6J3CV35
uniprot id: A0A6J3CXF6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vestigial family.
messages: May act as a specific coactivator for the mammalian TEFs.
messages: Nucleus

219594:EIF4A3
gene id: 219594:EIF4A3
uniprot id: A0A6J3CWL7
names: Similarity
messages: Belongs to the DEAD box helicase family.

219594:RECQL4
gene id: 219594:RECQL4
uniprot id: A0A6J3CI37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the helicase family. RecQ subfamily.
messages: Nucleus

219594:PFKP
gene id: 219594:PFKP
uniprot id: A0A6J3CGW4
uniprot id: A0A6J3CJL0
uniprot id: A0A6J3CLE5
uniprot id: A0A6J3CN18
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP, AMP, or fructose 2,6-bisphosphate, and allosterically inhibited by ATP or citrate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade "E" sub-subfamily.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homo- and heterotetramers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:SPTSSA
gene id: 219594:SPTSSA
uniprot id: A0A6J3D3L6
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

219594:MVP
gene id: 219594:MVP
uniprot id: A0A6J3EG04
names: Subcellular Location Annotation
messages: Cytoplasm

219594:LOC116496389
gene id: 219594:LOC116496389
uniprot id: A0A6J3DVC6
names: Similarity
messages: Belongs to the NDK family.

219594:ZPBP
gene id: 219594:ZPBP
uniprot id: A0A6J3CDC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the zona pellucida-binding protein Sp38 family.
messages: Secreted

219594:SMAD7
gene id: 219594:SMAD7
uniprot id: A0A6J3ED62
uniprot id: A0A6J3EGL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dwarfin/SMAD family.
messages: Cytoplasm
messages: Nucleus

219594:TBPL1
gene id: 219594:TBPL1
uniprot id: A0A6J3CVG7
names: Similarity
messages: Belongs to the TBP family.

219594:LOC116499096
gene id: 219594:LOC116499096
uniprot id: A0A6J3EE59
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

219594:SULT4A1
gene id: 219594:SULT4A1
uniprot id: A0A6J3CED4
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

219594:MLH1
gene id: 219594:MLH1
uniprot id: A0A6J3CJS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: Nucleus

219594:TGFBI
gene id: 219594:TGFBI
uniprot id: A0A6J3DQA1
names: Subcellular Location Annotation
messages: extracellular matrix

219594:EZH1
gene id: 219594:EZH1
uniprot id: A0A6J3EA34
uniprot id: A0A6J3EBI7
names: Subcellular Location Annotation
messages: Nucleus

219594:ASCC1
gene id: 219594:ASCC1
uniprot id: A0A6J3D6C0
uniprot id: A0A6J3D9L6
uniprot id: A0A6J3DBT5
uniprot id: A0A6J3DC96
names: Subcellular Location Annotation
messages: Cytoplasm

219594:ESYT1
gene id: 219594:ESYT1
uniprot id: A0A6J3EA87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the extended synaptotagmin family.
messages: Cell membrane
messages: Endoplasmic reticulum membrane
messages: Membrane

219594:SCG2
gene id: 219594:SCG2
uniprot id: A0A6J3DC95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromogranin/secretogranin protein family.
messages: Secreted

219594:EPN2
gene id: 219594:EPN2
uniprot id: A0A6J3DPI3
uniprot id: A0A6J3DTU0
names: Similarity
messages: Belongs to the epsin family.

219594:CCR9
gene id: 219594:CCR9
uniprot id: A0A6J3CDU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Early endosome
messages: Endosome
messages: Membrane

219594:HIP1
gene id: 219594:HIP1
uniprot id: A0A6J3E4L8
uniprot id: A0A6J3E5M6
names: Similarity
messages: Belongs to the SLA2 family.

219594:LOC116496126
gene id: 219594:LOC116496126
uniprot id: A0A6J3DZ39
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.

219594:LPGAT1
gene id: 219594:LPGAT1
uniprot id: A0A6J3CVH6
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

219594:IRAK4
gene id: 219594:IRAK4
uniprot id: A0A6J3EKZ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with MYD88 and IRAK2 to form a ternary complex called the Myddosome.
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. Pelle subfamily.
messages: Cytoplasm
messages: Serine/threonine-protein kinase that plays a critical role in initiating innate immune response against foreign pathogens.

219594:MPG
gene id: 219594:MPG
uniprot id: A0A6J3DUP0
names: Function
names: Similarity
messages: Belongs to the DNA glycosylase MPG family.
messages: Hydrolysis of the deoxyribose N-glycosidic bond to excise 3-methyladenine, and 7-methylguanine from the damaged DNA polymer formed by alkylation lesions.

219594:SEMA3G
gene id: 219594:SEMA3G
uniprot id: A0A6J3DI24
names: Caution
names: Similarity
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:STARD3NL
gene id: 219594:STARD3NL
uniprot id: A0A6J3CHG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STARD3 family.
messages: Endosome membrane
messages: Late endosome membrane
messages: Membrane

219594:C28H1orf43
gene id: 219594:C28H1orf43
uniprot id: A0A6J3EAY7
names: Function
names: Subcellular Location Annotation
messages: General regulator of phagocytosis. Required to uptake Gram negative bacterium by macrophages.
messages: Golgi apparatus
messages: Membrane
messages: Mitochondrion

219594:SH2B3
gene id: 219594:SH2B3
uniprot id: A0A6J3E087
names: Similarity
messages: Belongs to the SH2B adapter family.

219594:PLPPR3
gene id: 219594:PLPPR3
uniprot id: A0A6J3EDV0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Membrane

219594:ELMO3
gene id: 219594:ELMO3
uniprot id: A0A6J3DMM8
uniprot id: A0A6J3DPE5
uniprot id: A0A6J3DRC2
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Acts in association with DOCK1 and CRK. Was initially proposed to be required in complex with DOCK1 to activate Rac Rho small GTPases. May enhance the guanine nucleotide exchange factor (GEF) activity of DOCK1.

219594:PXMP4
gene id: 219594:PXMP4
uniprot id: A0A6J3DWV5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxisomal membrane protein PXMP2/4 family.
messages: Interacts with PEX19.
messages: Peroxisome membrane

219594:HNF1A
gene id: 219594:HNF1A
uniprot id: A0A6J3DVR7
uniprot id: A0A6J3DZT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HNF1 homeobox family.
messages: Nucleus

219594:LOC116498543
gene id: 219594:LOC116498543
uniprot id: A0A6J3EBJ6
names: Similarity
names: Subunit
messages: Belongs to the avian keratin family.
messages: The avian keratins (F-ker, S-ker, C-ker and B-ker) are a complex mixture of very similar polypeptides.

219594:LOC116500241
gene id: 219594:LOC116500241
uniprot id: A0A6J3EGJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:LOC116490489
gene id: 219594:LOC116490489
uniprot id: A0A6J3D8H8
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Enhances all basic T-cell responses to a foreign antigen, namely proliferation, secretion of lymphokines, up-regulation of molecules that mediate cell-cell interaction, and effective help for antibody secretion by B-cells. Essential both for efficient interaction between T and B-cells and for normal antibody responses to T-cell dependent antigens. Does not up-regulate the production of interleukin-2, but superinduces the synthesis of interleukin-10. Prevents the apoptosis of pre-activated T-cells. Plays a critical role in CD40-mediated class switching of immunoglobin isotypes.
messages: Homodimer; disulfide-linked.
messages: Membrane

219594:KMT2D
gene id: 219594:KMT2D
uniprot id: A0A6J3EFA6
names: Subcellular Location Annotation
messages: Nucleus

219594:NOP16
gene id: 219594:NOP16
uniprot id: A0A6J3DMP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOP16 family.
messages: nucleolus

219594:DARS1
gene id: 219594:DARS1
uniprot id: A0A6J3D5R1
names: Function
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 2 subfamily.
messages: Catalyzes the specific attachment of an amino acid to its cognate tRNA in a 2 step reaction: the amino acid (AA) is first activated by ATP to form AA-AMP and then transferred to the acceptor end of the tRNA.

219594:FOXM1
gene id: 219594:FOXM1
uniprot id: A0A6J3D6B7
uniprot id: A0A6J3D905
names: Subcellular Location Annotation
messages: Nucleus

219594:EBF2
gene id: 219594:EBF2
uniprot id: A0A6J3E9Y1
uniprot id: A0A6J3ED55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COE family.
messages: Nucleus

219594:ALOX5AP
gene id: 219594:ALOX5AP
uniprot id: A0A6J3EH57
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane

219594:RAD21
gene id: 219594:RAD21
uniprot id: A0A6J3CHZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the rad21 family.
messages: Nucleus

219594:PSME3IP1
gene id: 219594:PSME3IP1
uniprot id: A0A6J3DP82
names: Subcellular Location Annotation
messages: Nucleus

219594:TLR5
gene id: 219594:TLR5
uniprot id: A0A6J3CMY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Toll-like receptor family.
messages: Membrane

219594:SH3PXD2A
gene id: 219594:SH3PXD2A
uniprot id: A0A6J3D5Z7
uniprot id: A0A6J3D973
uniprot id: A0A6J3DBV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SH3PXD2 family.
messages: Cytoplasm
messages: podosome

219594:KAZALD1
gene id: 219594:KAZALD1
uniprot id: A0A6J3D940
names: Subcellular Location Annotation
messages: Secreted

219594:ARSI
gene id: 219594:ARSI
uniprot id: A0A6J3DT98
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

219594:KNG1
gene id: 219594:KNG1
uniprot id: A0A6J3DHH4
names: Subcellular Location Annotation
messages: extracellular space

219594:SLC16A6
gene id: 219594:SLC16A6
uniprot id: A0A6J3E0E8
names: Subcellular Location Annotation
messages: Membrane

219594:STRN
gene id: 219594:STRN
uniprot id: A0A6J3CMH4
uniprot id: A0A6J3CQ51
uniprot id: A0A6J3CSF8
uniprot id: A0A6J3CTJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat striatin family.
messages: Membrane

219594:OGDHL
gene id: 219594:OGDHL
uniprot id: A0A6J3DBP0
names: Similarity
messages: Belongs to the alpha-ketoglutarate dehydrogenase family.

219594:TRAF5
gene id: 219594:TRAF5
uniprot id: A0A6J3CTN2
uniprot id: A0A6J3CVX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TNF receptor-associated factor family.
messages: Cytoplasm

219594:AKAP8
gene id: 219594:AKAP8
uniprot id: A0A6J3EB06
uniprot id: A0A6J3ECC9
uniprot id: A0A6J3EFR5
uniprot id: A0A6J3EG25
uniprot id: A0A6J3EHP2
names: Similarity
messages: Belongs to the AKAP95 family.

219594:CDH8
gene id: 219594:CDH8
uniprot id: A0A6J3DMI9
uniprot id: A0A6J3DPI0
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane
messages: Membrane

219594:INHBA
gene id: 219594:INHBA
uniprot id: A0A6J3CLG9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TGF-beta family.
messages: Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins.
messages: Secreted

219594:CDC123
gene id: 219594:CDC123
uniprot id: A0A6J3D9A6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDC123 family.
messages: Cytoplasm
messages: Required for S phase entry of the cell cycle.

219594:EIF2A
gene id: 219594:EIF2A
uniprot id: A0A6J3DCX9
uniprot id: A0A6J3DIG8
names: Function
names: Similarity
messages: Belongs to the WD repeat EIF2A family.
messages: Functions in the early steps of protein synthesis of a small number of specific mRNAs. Acts by directing the binding of methionyl-tRNAi to 40S ribosomal subunits. In contrast to the eIF-2 complex, it binds methionyl-tRNAi to 40S subunits in a codon-dependent manner, whereas the eIF-2 complex binds methionyl-tRNAi to 40S subunits in a GTP-dependent manner.

219594:CCNL1
gene id: 219594:CCNL1
uniprot id: A0A6J3DEK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cyclin family. Cyclin L subfamily.
messages: Nucleus speckle
messages: nucleoplasm

219594:TFCP2L1
gene id: 219594:TFCP2L1
uniprot id: A0A6J3D4R3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the grh/CP2 family. CP2 subfamily.
messages: Nucleus

219594:LOC116502075
gene id: 219594:LOC116502075
uniprot id: A0A6J3EKA4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

219594:DNAJC10
gene id: 219594:DNAJC10
uniprot id: A0A6J3D769
names: Function
names: Subcellular Location Annotation
messages: Endoplasmic reticulum disulfide reductase involved both in the correct folding of proteins and degradation of misfolded proteins.
messages: Endoplasmic reticulum lumen

219594:PDE3A
gene id: 219594:PDE3A
uniprot id: A0A6J3DI07
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

219594:TRUB2
gene id: 219594:TRUB2
uniprot id: A0A6J3E0A5
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family.

219594:ENTPD7
gene id: 219594:ENTPD7
uniprot id: A0A6J3DCN4
names: Similarity
messages: Belongs to the GDA1/CD39 NTPase family.

219594:ANO2
gene id: 219594:ANO2
uniprot id: A0A6J3EJG2
uniprot id: A0A6J3EKS7
uniprot id: A0A6J3EPR1
uniprot id: A0A6J3EPT6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anoctamin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

219594:LOC116501433
gene id: 219594:LOC116501433
uniprot id: A0A6J3EI63
names: Similarity
messages: Belongs to the peptidase M14 family.

219594:LOC116489415
gene id: 219594:LOC116489415
uniprot id: A0A6J3D358
names: Similarity
messages: Belongs to the CD225/Dispanin family.

219594:STMN4
gene id: 219594:STMN4
uniprot id: A0A6J3CQ66
uniprot id: A0A6J3CSE1
uniprot id: A0A6J3CV67
uniprot id: A0A6J3CWA4
names: Similarity
messages: Belongs to the stathmin family.

219594:RAD18
gene id: 219594:RAD18
uniprot id: A0A6J3DIK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RAD18 family.
messages: Nucleus

219594:LOC116491322
gene id: 219594:LOC116491322
uniprot id: A0A6J3D9D5
names: Similarity
messages: Belongs to the cytochrome P450 family.

219594:OLFM2
gene id: 219594:OLFM2
uniprot id: A0A6J3EAZ2
uniprot id: A0A6J3EFQ0
uniprot id: A0A6J3EG08
names: Subcellular Location Annotation
messages: Secreted
messages: Synapse

219594:HOXB5
gene id: 219594:HOXB5
uniprot id: A0A6J3E9T0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus

219594:DLGAP3
gene id: 219594:DLGAP3
uniprot id: A0A6J3E9P8
names: Similarity
messages: Belongs to the SAPAP family.

219594:FAM91A1
gene id: 219594:FAM91A1
uniprot id: A0A6J3CJW7
names: Similarity
messages: Belongs to the FAM91 family.

219594:EIF2B1
gene id: 219594:EIF2B1
uniprot id: A0A6J3DZJ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eIF-2B alpha/beta/delta subunits family.
messages: Catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP.
messages: Complex of five different subunits; alpha, beta, gamma, delta and epsilon.

219594:ASPM
gene id: 219594:ASPM
uniprot id: A0A6J3DDF0
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

219594:LOC116499832
gene id: 219594:LOC116499832
uniprot id: A0A6J3EBJ4
names: Similarity
messages: Belongs to the intermediate filament family.

219594:LOC116502002
gene id: 219594:LOC116502002
uniprot id: A0A6J3ENU9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor T2R family.
messages: Membrane

219594:FZD9
gene id: 219594:FZD9
uniprot id: A0A6J3E4N9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor Fz/Smo family.
messages: Membrane

219594:TCAF2
gene id: 219594:TCAF2
uniprot id: A0A6J3EQF9
names: Similarity
messages: Belongs to the TCAF family.

219594:HOXC13
gene id: 219594:HOXC13
uniprot id: A0A6J3EHE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus

219594:RBBP7
gene id: 219594:RBBP7
uniprot id: A0A6J3DIN3
names: Subcellular Location Annotation
messages: Nucleus

219594:DYNC1H1
gene id: 219594:DYNC1H1
uniprot id: A0A6J3D471
names: Similarity
messages: Belongs to the dynein heavy chain family.

219594:EXOC4
gene id: 219594:EXOC4
uniprot id: A0A6J3CUL8
names: Function
names: Similarity
messages: Belongs to the SEC8 family.
messages: Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.

219594:NMUR1
gene id: 219594:NMUR1
uniprot id: A0A6J3DHB4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for the neuromedin-U and neuromedin-S neuropeptides.

219594:SEMA4G
gene id: 219594:SEMA4G
uniprot id: A0A6J3DB75
names: Caution
names: Similarity
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:TMEM267
gene id: 219594:TMEM267
uniprot id: A0A6J3EK67
names: Subcellular Location Annotation
messages: Membrane

219594:MCHR2
gene id: 219594:MCHR2
uniprot id: A0A6J3CSS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:COPB1
gene id: 219594:COPB1
uniprot id: A0A6J3CYZ4
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: COPI-coated vesicle membrane
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Membrane
messages: Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.
messages: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.

219594:GRM7
gene id: 219594:GRM7
uniprot id: A0A6J3DI48
uniprot id: A0A6J3DJE1
uniprot id: A0A6J3DLH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 3 family.
messages: Cell membrane
messages: Membrane

219594:TENM3
gene id: 219594:TENM3
uniprot id: A0A6J3CSH5
uniprot id: A0A6J3CSH9
uniprot id: A0A6J3CSI3
uniprot id: A0A6J3CUU2
uniprot id: A0A6J3CUU7
uniprot id: A0A6J3CV91
uniprot id: A0A6J3CV96
uniprot id: A0A6J3CXK3
uniprot id: A0A6J3CXL2
uniprot id: A0A6J3CXL7
uniprot id: A0A6J3CYN5
uniprot id: A0A6J3CYP2
uniprot id: A0A6J3CYP6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tenascin family. Teneurin subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

219594:APP
gene id: 219594:APP
uniprot id: A0A6J3CKW6
uniprot id: A0A6J3CQD6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the APP family.
messages: Cell membrane
messages: Cell surface
messages: Cytoplasm
messages: Endoplasmic reticulum
messages: Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis.
messages: Golgi apparatus
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Nucleus
messages: Secreted

219594:RAB27B
gene id: 219594:RAB27B
uniprot id: A0A6J3EIN8
uniprot id: A0A6J3EKC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Endosome
messages: Late endosome
messages: Membrane

219594:GSG1
gene id: 219594:GSG1
uniprot id: A0A6J3D831
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSG1 family.
messages: Membrane

219594:GRIA3
gene id: 219594:GRIA3
uniprot id: A0A6J3DKA2
uniprot id: A0A6J3DMR5
uniprot id: A0A6J3DMR8
uniprot id: A0A6J3DPJ0
uniprot id: A0A6J3DQQ7
uniprot id: A0A6J3DQR2
uniprot id: A0A6J3DRH3
uniprot id: A0A6J3DRH8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

219594:SF3B6
gene id: 219594:SF3B6
uniprot id: A0A6J3CL47
names: Subcellular Location Annotation
messages: Nucleus

219594:ABL2
gene id: 219594:ABL2
uniprot id: A0A6J3DFK1
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

219594:ADGRA3
gene id: 219594:ADGRA3
uniprot id: A0A6J3CZQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily.
messages: Membrane

219594:LOC116486751
gene id: 219594:LOC116486751
uniprot id: A0A6J3CM13
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

219594:ATF4
gene id: 219594:ATF4
uniprot id: A0A6J3EGJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family.
messages: Nucleus

219594:DTX4
gene id: 219594:DTX4
uniprot id: A0A6J3D0U1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Deltex family.
messages: Cytoplasm

219594:CUL4A
gene id: 219594:CUL4A
uniprot id: A0A6J3DEP4
names: Similarity
messages: Belongs to the cullin family.

219594:DUT
gene id: 219594:DUT
uniprot id: A0A6J3DHW1
uniprot id: A0A6J3DLZ7
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

219594:LOC116486143
gene id: 219594:LOC116486143
uniprot id: A0A6J3CGA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

219594:LOC116494534
gene id: 219594:LOC116494534
uniprot id: A0A6J3DLJ7
names: Caution
names: Subcellular Location Annotation
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

219594:RPS17
gene id: 219594:RPS17
uniprot id: A0A6J3DI77
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS17 family.

219594:LOC116500123
gene id: 219594:LOC116500123
uniprot id: A0A6J3ECI6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

219594:LOC116490554
gene id: 219594:LOC116490554
uniprot id: A0A6J3D5M5
uniprot id: A0A6J3D860
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family.
messages: Secreted

219594:LOC116501058
gene id: 219594:LOC116501058
uniprot id: A0A6J3EF11
names: Similarity
messages: Belongs to the avidin/streptavidin family.

219594:LOC116494635
gene id: 219594:LOC116494635
uniprot id: A0A6J3DM02
uniprot id: A0A6J3DS70
names: Similarity
messages: Belongs to the SLAIN motif-containing family.

219594:GPC5
gene id: 219594:GPC5
uniprot id: A0A6J3DVV4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glypican family.
messages: Cell membrane
messages: Cell surface proteoglycan that bears heparan sulfate.

219594:MDH1
gene id: 219594:MDH1
uniprot id: A0A6J3CRV7
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 2 family.

219594:DENND5A
gene id: 219594:DENND5A
uniprot id: A0A6J3CWW9
uniprot id: A0A6J3CZG0
uniprot id: A0A6J3D1Q4
uniprot id: A0A6J3D2V0
names: Caution
names: Similarity
messages: Belongs to the RAB6IP1 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:LOC116489485
gene id: 219594:LOC116489485
uniprot id: A0A6J3D2F1
names: Similarity
messages: Belongs to the NLRP family.

219594:ST7
gene id: 219594:ST7
uniprot id: A0A6J3DTU3
uniprot id: A0A6J3DUT6
uniprot id: A0A6J3DVM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ST7 family.
messages: Membrane

219594:TLE1
gene id: 219594:TLE1
uniprot id: A0A6J3EDQ0
uniprot id: A0A6J3EIJ7
uniprot id: A0A6J3EIY0
uniprot id: A0A6J3EKI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat Groucho/TLE family.
messages: Nucleus

219594:SIRT5
gene id: 219594:SIRT5
uniprot id: A0A6J3CK18
uniprot id: A0A6J3CLQ8
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sirtuin family. Class III subfamily.
messages: Binds 1 zinc ion per subunit.
messages: In contrast to class I sirtuins, class III sirtuins have only weak deacetylase activity. Difference in substrate specificity is probably due to a larger hydrophobic pocket with 2 residues (Tyr-102 and Arg-105) that bind to malonylated and succinylated substrates and define the specificity.
messages: In contrast to class I sirtuins, class III sirtuins have only weak deacetylase activity. Difference in substrate specificity is probably due to a larger hydrophobic pocket with 2 residues (Tyr-63 and Arg-66) that bind to malonylated and succinylated substrates and define the specificity.
messages: Mitochondrion
messages: NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Has weak NAD-dependent protein deacetylase activity; however this activity may not be physiologically relevant in vivo.
messages: Nucleus
messages: cytosol

219594:YES1
gene id: 219594:YES1
uniprot id: A0A6J3CJ61
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

219594:LOC116488888
gene id: 219594:LOC116488888
uniprot id: A0A6J3CX73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UDP-glycosyltransferase family.
messages: Membrane

219594:MTMR3
gene id: 219594:MTMR3
uniprot id: A0A6J3DTH0
uniprot id: A0A6J3DXN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.
messages: Cytoplasm
messages: Membrane

219594:SLC30A9
gene id: 219594:SLC30A9
uniprot id: A0A6J3CZ71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
messages: Cytoplasmic vesicle
messages: Endoplasmic reticulum
messages: Membrane
messages: Nucleus
messages: Vesicle

219594:NXT2
gene id: 219594:NXT2
uniprot id: A0A6J3DS92
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Has a role in nuclear-cytoplasmic transport of proteins and mRNAs.
messages: Nucleus

219594:KIF1B
gene id: 219594:KIF1B
uniprot id: A0A6J3E1K9
uniprot id: A0A6J3E1L3
uniprot id: A0A6J3E2X6
uniprot id: A0A6J3E2Y0
uniprot id: A0A6J3E2Y4
uniprot id: A0A6J3E5V4
uniprot id: A0A6J3E6L4
uniprot id: A0A6J3E6L9
uniprot id: A0A6J3E7U6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
messages: axon

219594:ABRAXAS2
gene id: 219594:ABRAXAS2
uniprot id: A0A6J3DDE3
names: Subcellular Location Annotation
messages: Nucleus

219594:LLGL1
gene id: 219594:LLGL1
uniprot id: A0A6J3DQT4
uniprot id: A0A6J3DV65
uniprot id: A0A6J3DW19
names: Similarity
messages: Belongs to the WD repeat L(2)GL family.

219594:CYFIP2
gene id: 219594:CYFIP2
uniprot id: A0A6J3DM58
uniprot id: A0A6J3DSB6
names: Similarity
messages: Belongs to the CYFIP family.

219594:DNAAF4
gene id: 219594:DNAAF4
uniprot id: A0A6J3DKB9
names: Subcellular Location Annotation
messages: Dynein axonemal particle
messages: neuron projection

219594:PEBP4
gene id: 219594:PEBP4
uniprot id: A0A6J3ECS0
names: Similarity
messages: Belongs to the phosphatidylethanolamine-binding protein family.

219594:TRIP12
gene id: 219594:TRIP12
uniprot id: A0A6J3DCW3
uniprot id: A0A6J3DFK7
uniprot id: A0A6J3DIE7
uniprot id: A0A6J3DIF3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPL family. K-HECT subfamily.
messages: E3 ubiquitin-protein ligase involved in ubiquitin fusion degradation (UFD) pathway and regulation of DNA repair. Part of the ubiquitin fusion degradation (UFD) pathway, a process that mediates ubiquitination of protein at their N-terminus, regardless of the presence of lysine residues in target proteins.
messages: nucleoplasm

219594:IFI30
gene id: 219594:IFI30
uniprot id: A0A6J3EC84
names: Similarity
names: Subunit
messages: Belongs to the GILT family.
messages: Dimer; disulfide-linked.

219594:SRSF2
gene id: 219594:SRSF2
uniprot id: A0A6J3E005
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the splicing factor SR family.
messages: Nucleus

219594:PRRC1
gene id: 219594:PRRC1
uniprot id: A0A6J3EI58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRRC1 family.
messages: Golgi apparatus

219594:LOC116486144
gene id: 219594:LOC116486144
uniprot id: A0A6J3CMI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family.
messages: Endosome membrane
messages: Late endosome membrane
messages: Membrane

219594:GIPC2
gene id: 219594:GIPC2
uniprot id: A0A6J3DEL0
uniprot id: A0A6J3DGR9
names: Similarity
messages: Belongs to the GIPC family.

219594:ROR1
gene id: 219594:ROR1
uniprot id: A0A6J3DCN2
uniprot id: A0A6J3DFR2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

219594:ANK1
gene id: 219594:ANK1
uniprot id: A0A6J3E846
uniprot id: A0A6J3E9M9
uniprot id: A0A6J3ECS7
uniprot id: A0A6J3ED73
uniprot id: A0A6J3ED83
uniprot id: A0A6J3EEX4
uniprot id: A0A6J3EEX9
names: Subcellular Location Annotation
messages: Membrane
messages: cytoskeleton

219594:LOC116501306
gene id: 219594:LOC116501306
uniprot id: A0A6J3ELD5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:RPL7A
gene id: 219594:RPL7A
uniprot id: A0A6J3DYF2
names: Function
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL8 family.
messages: Component of the ribosome.

219594:LOC116492513
gene id: 219594:LOC116492513
uniprot id: A0A6J3DF63
names: Similarity
messages: Belongs to the cytochrome P450 family.

219594:NUDT5
gene id: 219594:NUDT5
uniprot id: A0A6J3D9C3
names: Similarity
messages: Belongs to the Nudix hydrolase family.

219594:SPTLC3
gene id: 219594:SPTLC3
uniprot id: A0A6J3CW83
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

219594:S1PR1
gene id: 219594:S1PR1
uniprot id: A0A6J3DF96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:DOK5
gene id: 219594:DOK5
uniprot id: A0A6J3DTW9
uniprot id: A0A6J3DXX7
names: Similarity
messages: Belongs to the DOK family. Type B subfamily.

219594:FAM135B
gene id: 219594:FAM135B
uniprot id: A0A6J3CIX3
uniprot id: A0A6J3CK31
names: Similarity
messages: Belongs to the FAM135 family.

219594:ADAMTS7
gene id: 219594:ADAMTS7
uniprot id: A0A6J3DN35
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

219594:LOC116491834
gene id: 219594:LOC116491834
uniprot id: A0A6J3DF52
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UQCRH/QCR6 family.
messages: Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation.
messages: Mitochondrion inner membrane

219594:FGFR2
gene id: 219594:FGFR2
uniprot id: A0A6J3D6E4
uniprot id: A0A6J3D943
uniprot id: A0A6J3D948
uniprot id: A0A6J3D9P3
uniprot id: A0A6J3DBV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. Fibroblast growth factor receptor subfamily.
messages: Membrane

219594:CUL1
gene id: 219594:CUL1
uniprot id: A0A6J3CJ92
names: Similarity
messages: Belongs to the cullin family.

219594:S1PR4
gene id: 219594:S1PR4
uniprot id: A0A6J3E9F5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

219594:ACAP2
gene id: 219594:ACAP2
uniprot id: A0A6J3DBB6
uniprot id: A0A6J3DDY0
uniprot id: A0A6J3DF24
uniprot id: A0A6J3DGV6
names: Activity Regulation
names: Domain
names: Function
names: Subcellular Location Annotation
messages: Endosome membrane
messages: GAP activity stimulated by phosphatidylinositol 4,5-bisphosphate (PIP2) and phosphatidic acid.
messages: GTPase-activating protein for the ADP ribosylation factor family.
messages: PH domain binds phospholipids including phosphatidic acid, phosphatidylinositol 3-phosphate, phosphatidylinositol 3,5-bisphosphate (PIP2) and phosphatidylinositol 3,4,5-trisphosphate (PIP3). May mediate protein binding to PIP2 or PIP3 containing membranes.
messages: The BAR domain mediates homodimerization, it can neither bind membrane nor impart curvature, but instead requires the neighboring PH domain to achieve these functions.

219594:PAPOLG
gene id: 219594:PAPOLG
uniprot id: A0A6J3CKL1
uniprot id: A0A6J3CN85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the poly(A) polymerase family.
messages: Nucleus

219594:PPP1R12B
gene id: 219594:PPP1R12B
uniprot id: A0A6J3E674
uniprot id: A0A6J3E678
uniprot id: A0A6J3E7N9
uniprot id: A0A6J3E7P4
uniprot id: A0A6J3EAQ4
uniprot id: A0A6J3EBA1
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: PP1 comprises a catalytic subunit, and one or several targeting or regulatory subunits.

219594:LOC116502371
gene id: 219594:LOC116502371
uniprot id: A0A6J3EK20
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

219594:MYH9
gene id: 219594:MYH9
uniprot id: A0A6J3EKD7
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

219594:TMEM45A
gene id: 219594:TMEM45A
uniprot id: A0A6J3DHT7
uniprot id: A0A6J3DJF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM45 family.
messages: Membrane

219594:LOC116501301
gene id: 219594:LOC116501301
uniprot id: A0A6J3EG54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:LOC116486875
gene id: 219594:LOC116486875
uniprot id: A0A6J3CPP0
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

219594:PDP1
gene id: 219594:PDP1
uniprot id: A0A6J3CEE1
uniprot id: A0A6J3CG13
names: Similarity
messages: Belongs to the PP2C family.

219594:FSHB
gene id: 219594:FSHB
uniprot id: A0A6J3D0P3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycoprotein hormones subunit beta family.
messages: Secreted

219594:LOC116485691
gene id: 219594:LOC116485691
uniprot id: A0A6J3CG75
names: Similarity
names: Subunit
messages: Belongs to the avian keratin family.
messages: The avian keratins (F-ker, S-ker, C-ker and B-ker) are a complex mixture of very similar polypeptides.

219594:TRPM6
gene id: 219594:TRPM6
uniprot id: A0A6J3EHY7
names: Similarity
names: Subcellular Location Annotation
messages: In the C-terminal section; belongs to the protein kinase superfamily. Alpha-type protein kinase family. ALPK subfamily.
messages: Membrane

219594:LOC116487932
gene id: 219594:LOC116487932
uniprot id: A0A6J3CVW5
names: Similarity
messages: Belongs to the major facilitator (TC 2.A.1) superfamily. Organic cation transporter (TC 2.A.1.19) family.

219594:FAM98A
gene id: 219594:FAM98A
uniprot id: A0A6J3CQZ3
names: Similarity
messages: Belongs to the FAM98 family.

219594:LOC116486779
gene id: 219594:LOC116486779
uniprot id: A0A6J3CKZ9
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

219594:TPD52L1
gene id: 219594:TPD52L1
uniprot id: A0A6J3CNM5
uniprot id: A0A6J3CQK9
uniprot id: A0A6J3CRA9
uniprot id: A0A6J3CTJ9
names: Similarity
messages: Belongs to the TPD52 family.

219594:KRTCAP3
gene id: 219594:KRTCAP3
uniprot id: A0A6J3CND1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM54 family.
messages: Membrane

219594:IDNK
gene id: 219594:IDNK
uniprot id: A0A6J3EH67
names: Similarity
messages: Belongs to the gluconokinase GntK/GntV family.

219594:TMCO1
gene id: 219594:TMCO1
uniprot id: A0A6J3DGK9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMCO1 family.
messages: Calcium-selective channel required to prevent calcium stores from overfilling.
messages: Endoplasmic reticulum membrane
messages: Membrane

219594:ST6GALNAC6
gene id: 219594:ST6GALNAC6
uniprot id: A0A6J3E2K3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

219594:OTOP1
gene id: 219594:OTOP1
uniprot id: A0A6J3CWS4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the otopetrin family.
messages: Cell membrane
messages: Membrane

219594:CTNND1
gene id: 219594:CTNND1
uniprot id: A0A6J3D2K4
uniprot id: A0A6J3D2T5
uniprot id: A0A6J3D544
uniprot id: A0A6J3D620
names: Similarity
messages: Belongs to the beta-catenin family.

219594:TUBA1A
gene id: 219594:TUBA1A
uniprot id: A0A6J3EFS1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
messages: cytoskeleton

219594:MASP2
gene id: 219594:MASP2
uniprot id: A0A6J3E6U7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:NLK
gene id: 219594:NLK
uniprot id: A0A6J3E362
uniprot id: A0A6J3E505
names: Activity Regulation
names: Similarity
messages: Activated by threonine and tyrosine phosphorylation.
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.

219594:CZIB
gene id: 219594:CZIB
uniprot id: A0A6J3D903
uniprot id: A0A6J3DBQ6
uniprot id: A0A6J3DEQ2
names: Similarity
messages: Belongs to the UPF0587 family.

219594:B3GLCT
gene id: 219594:B3GLCT
uniprot id: A0A6J3E4A8
names: Subcellular Location Annotation
messages: Membrane

219594:CPN1
gene id: 219594:CPN1
uniprot id: A0A6J3DAA4
names: Similarity
messages: Belongs to the peptidase M14 family.

219594:MTMR4
gene id: 219594:MTMR4
uniprot id: A0A6J3E0F4
uniprot id: A0A6J3E330
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.
messages: Cytoplasm
messages: Membrane

219594:SYNM
gene id: 219594:SYNM
uniprot id: A0A6J3DM81
names: Similarity
messages: Belongs to the intermediate filament family.

219594:LOC116496454
gene id: 219594:LOC116496454
uniprot id: A0A6J3DXJ7
uniprot id: A0A6J3E1T4
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

219594:ARL1
gene id: 219594:ARL1
uniprot id: A0A6J3CXI4
names: Similarity
messages: Belongs to the small GTPase superfamily. Arf family.

219594:LOC116494450
gene id: 219594:LOC116494450
uniprot id: A0A6J3DSK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:LOC116491339
gene id: 219594:LOC116491339
uniprot id: A0A6J3D9G1
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

219594:MIP
gene id: 219594:MIP
uniprot id: A0A6J3EAF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

219594:PLCB2
gene id: 219594:PLCB2
uniprot id: A0A6J3D267
names: Function
messages: The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.

219594:CFAP97D1
gene id: 219594:CFAP97D1
uniprot id: A0A6J3E935
names: Similarity
messages: Belongs to the CFAP97 family.

219594:POGLUT2
gene id: 219594:POGLUT2
uniprot id: A0A6J3EKN4
names: Similarity
messages: Belongs to the KDELC family.

219594:PTGFR
gene id: 219594:PTGFR
uniprot id: A0A6J3DCV7
uniprot id: A0A6J3DG15
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

219594:KIF14
gene id: 219594:KIF14
uniprot id: A0A6J3D8D6
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

219594:SFXN5
gene id: 219594:SFXN5
uniprot id: A0A6J3CY79
uniprot id: A0A6J3D1Z2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sideroflexin family.
messages: Membrane
messages: Mitochondrion membrane

219594:MAEL
gene id: 219594:MAEL
uniprot id: A0A6J3ENP1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the maelstrom family.
messages: Nucleus
messages: Plays a central role during spermatogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Its association with piP-bodies suggests a participation in the secondary piRNAs metabolic process. Required for the localization of germ-cell factors to the meiotic nuage.

219594:IDH1
gene id: 219594:IDH1
uniprot id: A0A6J3D6R8
names: Cofactor
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

219594:LAPTM5
gene id: 219594:LAPTM5
uniprot id: A0A6J3E9Q3
names: Similarity
messages: Belongs to the LAPTM4/LAPTM5 transporter family.

219594:KDM4A
gene id: 219594:KDM4A
uniprot id: A0A6J3DBU2
names: Similarity
messages: Belongs to the JHDM3 histone demethylase family.

219594:HAT1
gene id: 219594:HAT1
uniprot id: A0A6J3DAA3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAT1 family.
messages: Catalytic subunit of the type B histone acetyltransferase (HAT) complex, composed of RBBP7 and HAT1. Interacts with histones H4 and H2A.
messages: Histone acetyltransferase that plays a role in different biological processes including cell cycle progression, glucose metabolism, histone production or DNA damage repair. Coordinates histone production and acetylation via H4 promoter binding. Acetylates histone H4 at 'Lys-5' (H4K5ac) and 'Lys-12' (H4K12ac) and, to a lesser extent, histone H2A at 'Lys-5' (H2AK5ac).

219594:IP6K3
gene id: 219594:IP6K3
uniprot id: A0A6J3EAX6
names: Similarity
messages: Belongs to the inositol phosphokinase (IPK) family.

219594:SHROOM2
gene id: 219594:SHROOM2
uniprot id: A0A6J3CVX8
uniprot id: A0A6J3D1Y3
uniprot id: A0A6J3D202
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the shroom family.
messages: cytoskeleton

219594:LOC116498289
gene id: 219594:LOC116498289
uniprot id: A0A6J3E957
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:GRB2
gene id: 219594:GRB2
uniprot id: A0A6J3DXR5
names: Subcellular Location Annotation
messages: Endosome
messages: Golgi apparatus
messages: Nucleus

219594:LOC116487462
gene id: 219594:LOC116487462
uniprot id: A0A6J3CTU8
names: Similarity
messages: Belongs to the GST superfamily. Alpha family.

219594:RAB3IP
gene id: 219594:RAB3IP
uniprot id: A0A6J3E9B7
uniprot id: A0A6J3EAT3
names: Similarity
messages: Belongs to the SEC2 family.

219594:PUF60
gene id: 219594:PUF60
uniprot id: A0A6J3CEE9
uniprot id: A0A6J3CH09
uniprot id: A0A6J3CIZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM half pint family.
messages: Nucleus

219594:TBL3
gene id: 219594:TBL3
uniprot id: A0A6J3DV87
names: Subcellular Location Annotation
messages: nucleolus

219594:ITGB8
gene id: 219594:ITGB8
uniprot id: A0A6J3CKU4
uniprot id: A0A6J3CMI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin beta chain family.
messages: Membrane

219594:LOC116487562
gene id: 219594:LOC116487562
uniprot id: A0A6J3CQQ1
names: Similarity
messages: Belongs to the GST superfamily. Alpha family.

219594:DDX43
gene id: 219594:DDX43
uniprot id: A0A6J3CPS4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family.
messages: Cytoplasm

219594:LOC116497061
gene id: 219594:LOC116497061
uniprot id: A0A6J3E3N9
uniprot id: A0A6J3E4N7
names: Similarity
messages: Belongs to the glycosyltransferase 92 family.

219594:LHPP
gene id: 219594:LHPP
uniprot id: A0A6J3DDC2
uniprot id: A0A6J3DDP6
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

219594:ITPA
gene id: 219594:ITPA
uniprot id: A0A6J3DDT7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 divalent metal cation per subunit; can use either Mg(2+) or Mn(2+).
messages: Cytoplasm
messages: Homodimer.
messages: Pyrophosphatase that hydrolyzes the non-canonical purine (dITP) as well as 2'-deoxy-N-6-hydroxylaminopurine triphosphate (dHAPTP) and xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions.

219594:FUT4
gene id: 219594:FUT4
uniprot id: A0A6J3END4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 10 family.
messages: Golgi stack membrane

219594:ENTPD8
gene id: 219594:ENTPD8
uniprot id: A0A6J3E265
names: Similarity
messages: Belongs to the GDA1/CD39 NTPase family.

219594:CORIN
gene id: 219594:CORIN
uniprot id: A0A6J3CTZ4
names: Caution
names: Subcellular Location Annotation
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:LOC116495782
gene id: 219594:LOC116495782
uniprot id: A0A6J3DUK9
names: Subcellular Location Annotation
messages: Membrane

219594:ENDOU
gene id: 219594:ENDOU
uniprot id: A0A6J3EEX7
names: Similarity
names: Subunit
messages: Belongs to the ENDOU family.
messages: Monomer.

219594:SEMA4D
gene id: 219594:SEMA4D
uniprot id: A0A6J3EBY2
uniprot id: A0A6J3EDA0
uniprot id: A0A6J3EGP8
uniprot id: A0A6J3EIK0
names: Caution
names: Similarity
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:NKAIN2
gene id: 219594:NKAIN2
uniprot id: A0A6J3CSJ3
uniprot id: A0A6J3CUU0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NKAIN family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

219594:NKD1
gene id: 219594:NKD1
uniprot id: A0A6J3DLB7
uniprot id: A0A6J3DMY3
uniprot id: A0A6J3DPY3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NKD family.
messages: Cell autonomous antagonist of the canonical Wnt signaling pathway.
messages: Cell membrane
messages: Cytoplasm
messages: Membrane

219594:COG2
gene id: 219594:COG2
uniprot id: A0A6J3CRM5
names: Similarity
messages: Belongs to the COG2 family.

219594:DTYMK
gene id: 219594:DTYMK
uniprot id: A0A6J3DFT8
names: Similarity
messages: Belongs to the thymidylate kinase family.

219594:MED13L
gene id: 219594:MED13L
uniprot id: A0A6J3DZB0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 13 family.
messages: Component of the Mediator complex, a coactivator involved in regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

219594:TXLNB
gene id: 219594:TXLNB
uniprot id: A0A6J3CSN2
names: Similarity
messages: Belongs to the taxilin family.

219594:LOC116497015
gene id: 219594:LOC116497015
uniprot id: A0A6J3E2N7
names: Similarity
messages: Belongs to the calycin superfamily. Lipocalin family.

219594:LOC116494974
gene id: 219594:LOC116494974
uniprot id: A0A6J3DTP7
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

219594:LGSN
gene id: 219594:LGSN
uniprot id: A0A6J3CN50
names: Similarity
messages: Belongs to the glutamine synthetase family.

219594:LOC116486553
gene id: 219594:LOC116486553
uniprot id: A0A6J3CN19
names: Function
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

219594:PRDM1
gene id: 219594:PRDM1
uniprot id: A0A6J3CT42
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class V-like SAM-binding methyltransferase superfamily.
messages: Cytoplasm
messages: Interacts with PRMT5. Interacts with FBXO10. Interacts with FBXO11.
messages: Nucleus
messages: Transcription factor that mediates a transcriptional program in various innate and adaptive immune tissue-resident lymphocyte T cell types such as tissue-resident memory T (Trm), natural killer (trNK) and natural killer T (NKT) cells and negatively regulates gene expression of proteins that promote the egress of tissue-resident T-cell populations from non-lymphoid organs. Plays a role in the development, retention and long-term establishment of adaptive and innate tissue-resident lymphocyte T cell types in non-lymphoid organs, such as the skin and gut, but also in other nonbarrier tissues like liver and kidney, and therefore may provide immediate immunological protection against reactivating infections or viral reinfection. Binds specifically to the PRDI element in the promoter of the beta-interferon gene. Drives the maturation of B-lymphocytes into Ig secreting cells. Associates with the transcriptional repressor ZNF683 to chromatin at gene promoter regions.

219594:PSMD3
gene id: 219594:PSMD3
uniprot id: A0A6J3E6J5
names: Similarity
messages: Belongs to the proteasome subunit S3 family.

219594:LAMB3
gene id: 219594:LAMB3
uniprot id: A0A6J3EDA3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:NR1H4
gene id: 219594:NR1H4
uniprot id: A0A6J3EIM8
uniprot id: A0A6J3ENV3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Nuclear hormone receptor that can act as a repressor or activator of transcription. High affinity receptor for thyroid hormones, including triiodothyronine and thyroxine.
messages: Nucleus

219594:ITPRIPL2
gene id: 219594:ITPRIPL2
uniprot id: A0A6J3DQA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ITPRIP family.
messages: Membrane

219594:LOC116501125
gene id: 219594:LOC116501125
uniprot id: A0A6J3EKL1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

219594:NME8
gene id: 219594:NME8
uniprot id: A0A6J3CFW7
names: Similarity
messages: Belongs to the NDK family.

219594:SLC2A13
gene id: 219594:SLC2A13
uniprot id: A0A6J3CSA3
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

219594:STARD5
gene id: 219594:STARD5
uniprot id: A0A6J3DKJ1
uniprot id: A0A6J3DM27
names: Function
messages: May be involved in the intracellular transport of sterols or other lipids. May bind cholesterol or other sterols.

219594:CNOT8
gene id: 219594:CNOT8
uniprot id: A0A6J3DPD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAF1 family.
messages: Nucleus

219594:CDK5
gene id: 219594:CDK5
uniprot id: A0A6J3CFK5
uniprot id: A0A6J3CH74
names: Similarity
messages: Belongs to the protein kinase superfamily.

219594:SLAIN2
gene id: 219594:SLAIN2
uniprot id: A0A6J3CTF9
uniprot id: A0A6J3CVS0
uniprot id: A0A6J3CZK8
names: Similarity
messages: Belongs to the SLAIN motif-containing family.

219594:ACTN2
gene id: 219594:ACTN2
uniprot id: A0A6J3CNI6
uniprot id: A0A6J3CQH2
uniprot id: A0A6J3CR76
uniprot id: A0A6J3CR79
uniprot id: A0A6J3CTG5
uniprot id: A0A6J3CTG7
names: Similarity
messages: Belongs to the alpha-actinin family.

219594:LOC116497746
gene id: 219594:LOC116497746
uniprot id: A0A6J3E6U1
names: Similarity
messages: Belongs to the 'GDXG' lipolytic enzyme family.

219594:SH3RF1
gene id: 219594:SH3RF1
uniprot id: A0A6J3CXG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SH3RF family.
messages: lamellipodium
messages: perinuclear region
messages: trans-Golgi network

219594:PDE8B
gene id: 219594:PDE8B
uniprot id: A0A6J3EF79
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family. PDE8 subfamily.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

219594:CEP63
gene id: 219594:CEP63
uniprot id: A0A6J3DCT9
uniprot id: A0A6J3DGR0
uniprot id: A0A6J3DID4
uniprot id: A0A6J3DIY4
names: Similarity
messages: Belongs to the CEP63 family.

219594:CEBPD
gene id: 219594:CEBPD
uniprot id: A0A6J3CKZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. C/EBP subfamily.
messages: Nucleus

219594:SLC16A10
gene id: 219594:SLC16A10
uniprot id: A0A6J3CP16
names: Subcellular Location Annotation
messages: Membrane

219594:LOC116490923
gene id: 219594:LOC116490923
uniprot id: A0A6J3D842
names: Subunit
messages: Monomer.

219594:PTX3
gene id: 219594:PTX3
uniprot id: A0A6J3DGL3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:LOC116498865
gene id: 219594:LOC116498865
uniprot id: A0A6J3E6C8
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family. Chitinase class II subfamily.

219594:ATG12
gene id: 219594:ATG12
uniprot id: A0A6J3EFR9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ATG12 family.
messages: Forms a conjugate with ATG5.
messages: Ubiquitin-like protein involved in autophagic vesicle formation.

219594:RARB
gene id: 219594:RARB
uniprot id: A0A6J3CBX7
uniprot id: A0A6J3CDL0
uniprot id: A0A6J3CEK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

219594:ZP4
gene id: 219594:ZP4
uniprot id: A0A6J3D6K1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZP domain family. ZPB subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Zona pellucida

219594:LOC116494458
gene id: 219594:LOC116494458
uniprot id: A0A6J3DQK0
uniprot id: A0A6J3DRL8
names: Subcellular Location Annotation
messages: Nucleus

219594:ACAP3
gene id: 219594:ACAP3
uniprot id: A0A6J3E228
uniprot id: A0A6J3E4X1
uniprot id: A0A6J3E5P6
uniprot id: A0A6J3E6S5
uniprot id: A0A6J3E6S9
names: Activity Regulation
names: Domain
names: Function
names: Subcellular Location Annotation
messages: Endosome membrane
messages: GAP activity stimulated by phosphatidylinositol 4,5-bisphosphate (PIP2) and phosphatidic acid.
messages: GTPase-activating protein for the ADP ribosylation factor family.
messages: PH domain binds phospholipids including phosphatidic acid, phosphatidylinositol 3-phosphate, phosphatidylinositol 3,5-bisphosphate (PIP2) and phosphatidylinositol 3,4,5-trisphosphate (PIP3). May mediate protein binding to PIP2 or PIP3 containing membranes.
messages: The BAR domain mediates homodimerization, it can neither bind membrane nor impart curvature, but instead requires the neighboring PH domain to achieve these functions.

219594:LOC116502353
gene id: 219594:LOC116502353
uniprot id: A0A6J3EQP0
names: Similarity
names: Subunit
messages: Belongs to the histone H3 family.
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

219594:LOC116499820
gene id: 219594:LOC116499820
uniprot id: A0A6J3EBI5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus
messages: Transcriptional repressor that contribute to growth arrest during terminal macrophage differentiation by repressing target genes involved in Ras-dependent proliferation. Represses MMP1 promoter activity.

219594:LOC116496452
gene id: 219594:LOC116496452
uniprot id: A0A6J3DXJ2
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

219594:CNKSR3
gene id: 219594:CNKSR3
uniprot id: A0A6J3CR63
uniprot id: A0A6J3CS70
names: Similarity
messages: Belongs to the CNKSR family.

219594:TACR2
gene id: 219594:TACR2
uniprot id: A0A6J3D9L3
uniprot id: A0A6J3DCE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:DNMBP
gene id: 219594:DNMBP
uniprot id: A0A6J3DDU8
names: Subcellular Location Annotation
messages: Cell junction
messages: Golgi stack
messages: Synapse
messages: cytoskeleton

219594:LOC116493153
gene id: 219594:LOC116493153
uniprot id: A0A6J3DFD2
names: Similarity
messages: Belongs to the FAM20 family.

219594:PABPC1L
gene id: 219594:PABPC1L
uniprot id: A0A6J3DYZ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyadenylate-binding protein type-1 family.
messages: Binds the poly(A) tail of mRNA.
messages: Cytoplasm

219594:MIEF2
gene id: 219594:MIEF2
uniprot id: A0A6J3DVG9
names: Subcellular Location Annotation
messages: Membrane
messages: Mitochondrion outer membrane

219594:LAMC2
gene id: 219594:LAMC2
uniprot id: A0A6J3DAB3
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: basement membrane

219594:PROS1
gene id: 219594:PROS1
uniprot id: A0A6J3CKI6
uniprot id: A0A6J3CKJ7
names: Caution
names: Function
messages: Anticoagulant plasma protein; it is a cofactor to activated protein C in the degradation of coagulation factors Va and VIIIa. It helps to prevent coagulation and stimulating fibrinolysis.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:NOC4L
gene id: 219594:NOC4L
uniprot id: A0A6J3DWA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CBF/MAK21 family.
messages: Nucleus membrane

219594:NRXN3
gene id: 219594:NRXN3
uniprot id: A0A6J3CZK9
uniprot id: A0A6J3CZL4
uniprot id: A0A6J3CZL9
uniprot id: A0A6J3CZM6
uniprot id: A0A6J3D213
uniprot id: A0A6J3D218
uniprot id: A0A6J3D222
uniprot id: A0A6J3D259
uniprot id: A0A6J3D265
uniprot id: A0A6J3D270
uniprot id: A0A6J3D4J8
uniprot id: A0A6J3D4K7
uniprot id: A0A6J3D5I9
uniprot id: A0A6J3D5J1
uniprot id: A0A6J3D5J6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neurexin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

219594:SNTG1
gene id: 219594:SNTG1
uniprot id: A0A6J3CE31
uniprot id: A0A6J3CF28
uniprot id: A0A6J3CGX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the syntrophin family.
messages: cytoskeleton

219594:LOC116500673
gene id: 219594:LOC116500673
uniprot id: A0A6J3EIJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

219594:LOC116490193
gene id: 219594:LOC116490193
uniprot id: A0A6J3D1A0
uniprot id: A0A6J3D3Y7
uniprot id: A0A6J3D743
names: Similarity
messages: Belongs to the Luc7 family.

219594:INHBB
gene id: 219594:INHBB
uniprot id: A0A6J3D711
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TGF-beta family.
messages: Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins.
messages: Secreted

219594:LOC116493989
gene id: 219594:LOC116493989
uniprot id: A0A6J3DLW4
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane
messages: Membrane

219594:HSCB
gene id: 219594:HSCB
uniprot id: A0A6J3DWG8
names: Similarity
messages: Belongs to the HscB family.

219594:STRIP2
gene id: 219594:STRIP2
uniprot id: A0A6J3DPL3
names: Similarity
messages: Belongs to the STRIP family.

219594:RNASET2
gene id: 219594:RNASET2
uniprot id: A0A6J3CPE8
uniprot id: A0A6J3CVI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase T2 family.
messages: Lysosome lumen

219594:GPX2
gene id: 219594:GPX2
uniprot id: A0A6J3D3U9
names: Similarity
messages: Belongs to the glutathione peroxidase family.

219594:ELOC
gene id: 219594:ELOC
uniprot id: A0A6J3CHN3
names: Similarity
messages: Belongs to the SKP1 family.

219594:TSPO
gene id: 219594:TSPO
uniprot id: A0A6J3CKW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TspO/BZRP family.
messages: Membrane

219594:LOC116499341
gene id: 219594:LOC116499341
uniprot id: A0A6J3EDD3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:DDX24
gene id: 219594:DDX24
uniprot id: A0A6J3D0M8
names: Similarity
messages: Belongs to the DEAD box helicase family.

219594:SELENOF
gene id: 219594:SELENOF
uniprot id: A0A6J3DFG7
names: Similarity
messages: Belongs to the selenoprotein M/F family.

219594:HOXA3
gene id: 219594:HOXA3
uniprot id: A0A6J3CL26
uniprot id: A0A6J3CMQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus

219594:LOC116494670
gene id: 219594:LOC116494670
uniprot id: A0A6J3DRG2
names: Subcellular Location Annotation
messages: Secreted

219594:NDUFC1
gene id: 219594:NDUFC1
uniprot id: A0A6J3CW22
names: Similarity
names: Subunit
messages: Belongs to the complex I NDUFC1 subunit family.
messages: Complex I is composed of 45 different subunits.

219594:LRRC8C
gene id: 219594:LRRC8C
uniprot id: A0A6J3DES6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LRRC8 family.
messages: Cell membrane
messages: Membrane

219594:LOC116498201
gene id: 219594:LOC116498201
uniprot id: A0A6J3E3Z3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the E2F/DP family.
messages: Nucleus

219594:TMEM43
gene id: 219594:TMEM43
uniprot id: A0A6J3DLI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM43 family.
messages: Membrane

219594:LAMB2
gene id: 219594:LAMB2
uniprot id: A0A6J3DHY9
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: basement membrane

219594:PLAG1
gene id: 219594:PLAG1
uniprot id: A0A6J3CHH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the krueppel C2H2-type zinc-finger protein family.
messages: Nucleus

219594:SPCS3
gene id: 219594:SPCS3
uniprot id: A0A6J3CVZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPCS3 family.
messages: Endoplasmic reticulum membrane

219594:SMC2
gene id: 219594:SMC2
uniprot id: A0A6J3EK73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMC family. SMC2 subfamily.
messages: Chromosome
messages: Nucleus

219594:LOC116501448
gene id: 219594:LOC116501448
uniprot id: A0A6J3EM11
names: Similarity
messages: Belongs to the GSKIP family.

219594:MAPK9
gene id: 219594:MAPK9
uniprot id: A0A6J3DNP2
uniprot id: A0A6J3DQZ5
uniprot id: A0A6J3DT01
uniprot id: A0A6J3DTV9
uniprot id: A0A6J3DTW2
uniprot id: A0A6J3DUR3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.
messages: Cytoplasm
messages: Responds to activation by environmental stress and pro-inflammatory cytokines by phosphorylating a number of transcription factors, and thus regulates transcriptional activity.

219594:CPSF6
gene id: 219594:CPSF6
uniprot id: A0A6J3CI48
uniprot id: A0A6J3CI58
uniprot id: A0A6J3CI75
uniprot id: A0A6J3CKU9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM CPSF6/7 family.
messages: Cytoplasm
messages: Nucleus speckle
messages: nucleoplasm

219594:KCNB1
gene id: 219594:KCNB1
uniprot id: A0A6J3DVL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the potassium channel family. B (Shab) (TC 1.A.1.2) subfamily. Kv2.1/KCNB1 sub-subfamily.
messages: Lateral cell membrane
messages: Membrane
messages: Perikaryon
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane
messages: axon
messages: sarcolemma
messages: synaptosome

219594:LOC116501309
gene id: 219594:LOC116501309
uniprot id: A0A6J3EHM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:RNF152
gene id: 219594:RNF152
uniprot id: A0A6J3CMS1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNF152 family.
messages: Lysosome membrane
messages: Membrane

219594:DDX55
gene id: 219594:DDX55
uniprot id: A0A6J3E058
names: Similarity
messages: Belongs to the DEAD box helicase family.

219594:SNUPN
gene id: 219594:SNUPN
uniprot id: A0A6J3DL53
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snurportin family.
messages: Cytoplasm
messages: Functions as an U snRNP-specific nuclear import adapter. Involved in the trimethylguanosine (m3G)-cap-dependent nuclear import of U snRNPs. Binds specifically to the terminal m3G-cap U snRNAs.
messages: Nucleus

219594:METTL8
gene id: 219594:METTL8
uniprot id: A0A6J3D595
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. METL family.
messages: S-adenosyl-L-methionine-dependent methyltransferase.

219594:TMEM178B
gene id: 219594:TMEM178B
uniprot id: A0A6J3EJN7
names: Similarity
messages: Belongs to the TMEM178 family.

219594:TEKT3
gene id: 219594:TEKT3
uniprot id: A0A6J3DY79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tektin family.
messages: flagellum

219594:HR
gene id: 219594:HR
uniprot id: A0A6J3ECW9
names: Subcellular Location Annotation
messages: Nucleus

219594:IMMT
gene id: 219594:IMMT
uniprot id: A0A6J3CSI9
uniprot id: A0A6J3CUV2
uniprot id: A0A6J3CVA1
uniprot id: A0A6J3CYQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MICOS complex subunit Mic60 family.
messages: Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.
messages: Component of the mitochondrial contact site and cristae organizing system (MICOS) complex.
messages: Mitochondrion inner membrane

219594:NCOR1
gene id: 219594:NCOR1
uniprot id: A0A6J3E3C2
uniprot id: A0A6J3E453
uniprot id: A0A6J3E459
names: Similarity
messages: Belongs to the N-CoR nuclear receptor corepressors family.

219594:ATP5MC3
gene id: 219594:ATP5MC3
uniprot id: A0A6J3DAC8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Membrane
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. A homomeric c-ring of probably 10 subunits is part of the complex rotary element.
messages: Mitochondrion membrane

219594:EMP2
gene id: 219594:EMP2
uniprot id: A0A6J3DX79
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the PMP-22/EMP/MP20 family.
messages: Cell membrane
messages: Golgi apparatus membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Membrane raft
messages: Nucleus
messages: perinuclear region

219594:CNNM1
gene id: 219594:CNNM1
uniprot id: A0A6J3DC77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ACDP family.
messages: Membrane

219594:LOC116499742
gene id: 219594:LOC116499742
uniprot id: A0A6J3E9U3
names: Similarity
names: Subunit
messages: Belongs to the avian keratin family.
messages: The avian keratins (F-ker, S-ker, C-ker and B-ker) are a complex mixture of very similar polypeptides.

219594:LOC116493720
gene id: 219594:LOC116493720
uniprot id: A0A6J3DMC5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase subunit 5A family.
messages: Component of the cytochrome c oxidase (complex IV, CIV), a multisubunit enzyme composed of a catalytic core of 3 subunits and several supernumerary subunits. The complex exists as a monomer or a dimer and forms supercomplexes (SCs) in the inner mitochondrial membrane with ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII).
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
messages: Mitochondrion inner membrane

219594:SFMBT1
gene id: 219594:SFMBT1
uniprot id: A0A6J3DK16
names: Subcellular Location Annotation
messages: Nucleus

219594:ADPRS
gene id: 219594:ADPRS
uniprot id: A0A6J3E838
names: Similarity
messages: Belongs to the ADP-ribosylglycohydrolase family.

219594:CLDN34
gene id: 219594:CLDN34
uniprot id: A0A6J3DUU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: tight junction

219594:TMEM9
gene id: 219594:TMEM9
uniprot id: A0A6J3EBJ7
names: Similarity
messages: Belongs to the TMEM9 family.

219594:NKX3-1
gene id: 219594:NKX3-1
uniprot id: A0A6J3EFN5
names: Subcellular Location Annotation
messages: Nucleus

219594:GTPBP8
gene id: 219594:GTPBP8
uniprot id: A0A6J3DI28
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.

219594:NADK
gene id: 219594:NADK
uniprot id: A0A6J3E790
names: Similarity
messages: Belongs to the NAD kinase family.

219594:LOC116492094
gene id: 219594:LOC116492094
uniprot id: A0A6J3DAI4
names: Similarity
messages: Belongs to the folate receptor family.

219594:OGT
gene id: 219594:OGT
uniprot id: A0A6J3DLW5
uniprot id: A0A6J3DR59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 41 family. O-GlcNAc transferase subfamily.
messages: Cell projection
messages: Mitochondrion membrane

219594:TBP
gene id: 219594:TBP
uniprot id: A0A6J3CVR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TBP family.
messages: Nucleus

219594:FGFR1
gene id: 219594:FGFR1
uniprot id: A0A6J3E8E8
uniprot id: A0A6J3E9W8
uniprot id: A0A6J3ED36
uniprot id: A0A6J3EDH7
uniprot id: A0A6J3EF71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. Fibroblast growth factor receptor subfamily.
messages: Cytoplasmic vesicle
messages: Membrane
messages: Nucleus
messages: Vesicle
messages: cytosol

219594:PHTF2
gene id: 219594:PHTF2
uniprot id: A0A6J3CED5
uniprot id: A0A6J3CEH6
names: Subcellular Location Annotation
messages: Membrane

219594:LOC116486729
gene id: 219594:LOC116486729
uniprot id: A0A6J3CNW7
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

219594:GUCY2C
gene id: 219594:GUCY2C
uniprot id: A0A6J3EBH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Membrane

219594:TES
gene id: 219594:TES
uniprot id: A0A6J3EP32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prickle / espinas / testin family.
messages: focal adhesion

219594:GFRA1
gene id: 219594:GFRA1
uniprot id: A0A6J3D8N1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GDNFR family.
messages: Cell membrane
messages: Membrane

219594:DMRT3
gene id: 219594:DMRT3
uniprot id: A0A6J3ELC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DMRT family.
messages: Nucleus

219594:PDE6C
gene id: 219594:PDE6C
uniprot id: A0A6J3DB85
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

219594:LOC116485665
gene id: 219594:LOC116485665
uniprot id: A0A6J3CG55
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

219594:FOXD3
gene id: 219594:FOXD3
uniprot id: A0A6J3DC69
names: Subcellular Location Annotation
messages: Nucleus

219594:LOC116490054
gene id: 219594:LOC116490054
uniprot id: A0A6J3D0I1
names: Domain
names: Subcellular Location Annotation
messages: The N-terminal C2 domain associates with lipid membranes upon calcium binding.
messages: cytosol

219594:MAGOH
gene id: 219594:MAGOH
uniprot id: A0A6J3DFK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mago nashi family.
messages: Nucleus

219594:FAM214A
gene id: 219594:FAM214A
uniprot id: A0A6J3DG85
uniprot id: A0A6J3DLT1
uniprot id: A0A6J3DM99
names: Similarity
messages: Belongs to the FAM214 family.

219594:PLXNB1
gene id: 219594:PLXNB1
uniprot id: A0A6J3DGY0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the plexin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

219594:DLGAP2
gene id: 219594:DLGAP2
uniprot id: A0A6J3CPB5
uniprot id: A0A6J3CRA7
uniprot id: A0A6J3CRB0
uniprot id: A0A6J3CRY8
uniprot id: A0A6J3CUA3
uniprot id: A0A6J3CVF1
names: Similarity
messages: Belongs to the SAPAP family.

219594:GALNT17
gene id: 219594:GALNT17
uniprot id: A0A6J3E443
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

219594:PEPD
gene id: 219594:PEPD
uniprot id: A0A6J3DNH9
names: Similarity
messages: Belongs to the peptidase M24B family.

219594:ATP11B
gene id: 219594:ATP11B
uniprot id: A0A6J3DDK0
uniprot id: A0A6J3DDL0
uniprot id: A0A6J3DGA3
uniprot id: A0A6J3DGA7
uniprot id: A0A6J3DHI8
uniprot id: A0A6J3DJ48
uniprot id: A0A6J3DJ57
uniprot id: A0A6J3DJP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

219594:SLITRK5
gene id: 219594:SLITRK5
uniprot id: A0A6J3CDX1
names: Similarity
messages: Belongs to the SLITRK family.

219594:LOC116493115
gene id: 219594:LOC116493115
uniprot id: A0A6J3DLB2
names: Similarity
messages: Belongs to the protein kinase superfamily.

219594:TASP1
gene id: 219594:TASP1
uniprot id: A0A6J3CP27
uniprot id: A0A6J3CR15
uniprot id: A0A6J3CRQ9
uniprot id: A0A6J3CU02
uniprot id: A0A6J3CV51
names: Similarity
messages: Belongs to the Ntn-hydrolase family.

219594:LOC116489921
gene id: 219594:LOC116489921
uniprot id: A0A6J3D4S2
names: Domain
names: Subcellular Location Annotation
messages: The N-terminal C2 domain associates with lipid membranes upon calcium binding.
messages: cytosol

219594:CACNA2D1
gene id: 219594:CACNA2D1
uniprot id: A0A6J3D3S2
uniprot id: A0A6J3D6E6
uniprot id: A0A6J3D6W1
uniprot id: A0A6J3D955
names: Similarity
messages: Belongs to the calcium channel subunit alpha-2/delta family.

219594:SUGT1
gene id: 219594:SUGT1
uniprot id: A0A6J3ENS8
names: Similarity
messages: Belongs to the SGT1 family.

219594:ST6GALNAC5
gene id: 219594:ST6GALNAC5
uniprot id: A0A6J3DGS4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

219594:LOC116501342
gene id: 219594:LOC116501342
uniprot id: A0A6J3EHQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:LOC116488294
gene id: 219594:LOC116488294
uniprot id: A0A6J3CXK6
names: Similarity
messages: Belongs to the peptidase C2 family.

219594:AFMID
gene id: 219594:AFMID
uniprot id: A0A6J3E104
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the kynurenine formamidase family.
messages: Catalyzes the hydrolysis of N-formyl-L-kynurenine to L-kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Kynurenine may be further oxidized to nicotinic acid, NAD(H) and NADP(H). Required for elimination of toxic metabolites.
messages: Homodimer.
messages: Nucleus
messages: The main chain amide nitrogen atoms of the second glycine and its adjacent residue in the HGGXW motif define the oxyanion hole, and stabilize the oxyanion that forms during the nucleophilic attack by the catalytic serine during substrate cleavage.
messages: cytosol

219594:LOC116486644
gene id: 219594:LOC116486644
uniprot id: A0A6J3CNJ2
names: Similarity
names: Subunit
messages: Belongs to the avian keratin family.
messages: The avian keratins (F-ker, S-ker, C-ker and B-ker) are a complex mixture of very similar polypeptides.

219594:WFIKKN1
gene id: 219594:WFIKKN1
uniprot id: A0A6J3DQ25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WFIKKN family.
messages: Secreted

219594:ITM2B
gene id: 219594:ITM2B
uniprot id: A0A6J3E1V1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ITM2 family.
messages: Membrane

219594:SOX8
gene id: 219594:SOX8
uniprot id: A0A6J3DVP3
names: Subcellular Location Annotation
messages: Nucleus

219594:SLC7A2
gene id: 219594:SLC7A2
uniprot id: A0A6J3D0D7
uniprot id: A0A6J3D1I9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Cationic amino acid transporter (CAT) (TC 2.A.3.3) family.
messages: Cell membrane
messages: Membrane

219594:PCNA
gene id: 219594:PCNA
uniprot id: A0A6J3EA83
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PCNA family.
messages: Nucleus
messages: This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand.

219594:MRPS33
gene id: 219594:MRPS33
uniprot id: A0A6J3EAF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mS33 family.
messages: Mitochondrion

219594:LOC116492034
gene id: 219594:LOC116492034
uniprot id: A0A6J3DG01
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c-type heme lyase family.
messages: Lyase that catalyzes the covalent linking of the heme group to the cytochrome C apoprotein to produce the mature functional cytochrome.
messages: Membrane
messages: Mitochondrion inner membrane

219594:ZCCHC17
gene id: 219594:ZCCHC17
uniprot id: A0A6J3EA92
names: Subcellular Location Annotation
messages: nucleolus

219594:PTDSS2
gene id: 219594:PTDSS2
uniprot id: A0A6J3D3E9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphatidyl serine synthase family.
messages: Catalyzes a base-exchange reaction in which the polar head group of phosphatidylethanolamine (PE) is replaced by L-serine.
messages: Endoplasmic reticulum membrane
messages: Membrane

219594:CLU
gene id: 219594:CLU
uniprot id: A0A6J3CQK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the clusterin family.
messages: Endoplasmic reticulum
messages: Membrane
messages: Mitochondrion membrane
messages: Nucleus
messages: Secreted
messages: chromaffin granule
messages: cytosol

219594:TGM2
gene id: 219594:TGM2
uniprot id: A0A6J3DYW8
names: Cofactor
names: Similarity
messages: Belongs to the transglutaminase superfamily. Transglutaminase family.
messages: Binds 1 Ca(2+) ion per subunit.

219594:LOC116488437
gene id: 219594:LOC116488437
uniprot id: A0A6J3CU78
names: Similarity
messages: Belongs to the pancreatic ribonuclease family.

219594:EMC1
gene id: 219594:EMC1
uniprot id: A0A6J3E1F0
uniprot id: A0A6J3E5N9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EMC1 family.
messages: Component of the ER membrane protein complex (EMC).
messages: Endoplasmic reticulum membrane
messages: Membrane

219594:KYAT3
gene id: 219594:KYAT3
uniprot id: A0A6J3DBL6
uniprot id: A0A6J3DEJ9
names: Subunit
messages: Homodimer.

219594:SLC2A8
gene id: 219594:SLC2A8
uniprot id: A0A6J3DZN1
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

219594:MFSD6
gene id: 219594:MFSD6
uniprot id: A0A6J3D584
uniprot id: A0A6J3D7T1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. MFSD6 family.
messages: Membrane

219594:MLN
gene id: 219594:MLN
uniprot id: A0A6J3E7Z8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the motilin family.
messages: Plays an important role in the regulation of interdigestive gastrointestinal motility and indirectly causes rhythmic contraction of duodenal and colonic smooth muscle.
messages: Secreted

219594:CEP44
gene id: 219594:CEP44
uniprot id: A0A6J3CVU0
names: Subcellular Location Annotation
messages: Midbody
messages: centriole
messages: spindle pole

219594:SAP30L
gene id: 219594:SAP30L
uniprot id: A0A6J3DTN9
names: Similarity
messages: Belongs to the SAP30 family.

219594:EZR
gene id: 219594:EZR
uniprot id: A0A6J3CVK4
uniprot id: A0A6J3CWQ7
names: Subcellular Location Annotation
messages: Membrane
messages: cytoskeleton

219594:SLC26A1
gene id: 219594:SLC26A1
uniprot id: A0A6J3ED84
uniprot id: A0A6J3EK21
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Mediates sulfate transport with high affinity. Mediates oxalate transport. Mediates bicarbonate transport. Does not accept succinate as cosubstrate.
messages: Membrane

219594:C13HXorf56
gene id: 219594:C13HXorf56
uniprot id: A0A6J3DRN6
names: Similarity
messages: Belongs to the STEEP1 family.

219594:HMGN3
gene id: 219594:HMGN3
uniprot id: A0A6J3CRN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HMGN family.
messages: Nucleus

219594:NLN
gene id: 219594:NLN
uniprot id: A0A6J3EK33
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

219594:DDX59
gene id: 219594:DDX59
uniprot id: A0A6J3DB84
names: Similarity
messages: Belongs to the DEAD box helicase family. DDX59 subfamily.

219594:TLR4
gene id: 219594:TLR4
uniprot id: A0A6J3DZP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Toll-like receptor family.
messages: Membrane

219594:MRPS23
gene id: 219594:MRPS23
uniprot id: A0A6J3E0Y6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mS23 family.
messages: Mitochondrion

219594:STAT1
gene id: 219594:STAT1
uniprot id: A0A6J3D7Q2
uniprot id: A0A6J3D8J2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transcription factor STAT family.
messages: Cytoplasm
messages: Nucleus

219594:ARL3
gene id: 219594:ARL3
uniprot id: A0A6J3D8W5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: centrosome

219594:SV2B
gene id: 219594:SV2B
uniprot id: A0A6J3DJ18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily.
messages: Membrane
messages: synaptic vesicle membrane

219594:EZH2
gene id: 219594:EZH2
uniprot id: A0A6J3CHR0
uniprot id: A0A6J3CJ89
uniprot id: A0A6J3CME1
uniprot id: A0A6J3CNV4
names: Subcellular Location Annotation
messages: Nucleus

219594:ATAD1
gene id: 219594:ATAD1
uniprot id: A0A6J3DBK3
uniprot id: A0A6J3DC14
names: Similarity
messages: Belongs to the AAA ATPase family.

219594:RHBDL1
gene id: 219594:RHBDL1
uniprot id: A0A6J3DPB2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S54 family.
messages: Membrane

219594:MRPS9
gene id: 219594:MRPS9
uniprot id: A0A6J3E7R7
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

219594:MARK1
gene id: 219594:MARK1
uniprot id: A0A6J3CLT3
uniprot id: A0A6J3CNI3
uniprot id: A0A6J3CRR6
uniprot id: A0A6J3CSS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily.
messages: dendrite

219594:HRH1
gene id: 219594:HRH1
uniprot id: A0A6J3DF15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:TMED10
gene id: 219594:TMED10
uniprot id: A0A6J3D176
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Endoplasmic reticulum membrane
messages: Membrane

219594:GLYATL3
gene id: 219594:GLYATL3
uniprot id: A0A6J3CSW9
names: Similarity
messages: Belongs to the glycine N-acyltransferase family.

219594:ATXN1
gene id: 219594:ATXN1
uniprot id: A0A6J3CHW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATXN1 family.
messages: Nucleus

219594:LGR4
gene id: 219594:LGR4
uniprot id: A0A6J3D5P1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

219594:GOLT1B
gene id: 219594:GOLT1B
uniprot id: A0A6J3ELE4
uniprot id: A0A6J3EMU6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GOT1 family.
messages: Golgi apparatus membrane
messages: May be involved in fusion of ER-derived transport vesicles with the Golgi complex.
messages: Membrane

219594:CHST1
gene id: 219594:CHST1
uniprot id: A0A6J3D226
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 1 family. Gal/GlcNAc/GalNAc subfamily.
messages: Membrane

219594:GLI1
gene id: 219594:GLI1
uniprot id: A0A6J3EBJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GLI C2H2-type zinc-finger protein family.
messages: Nucleus

219594:USP43
gene id: 219594:USP43
uniprot id: A0A6J3DYI7
names: Similarity
messages: Belongs to the peptidase C19 family.

219594:EMC2
gene id: 219594:EMC2
uniprot id: A0A6J3CIA0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EMC2 family.
messages: Component of the ER membrane protein complex (EMC).
messages: Endoplasmic reticulum membrane
messages: Part of the endoplasmic reticulum membrane protein complex (EMC) that enables the energy-independent insertion into endoplasmic reticulum membranes of newly synthesized membrane proteins.

219594:C1H12orf75
gene id: 219594:C1H12orf75
uniprot id: A0A6J3EIE4
uniprot id: A0A6J3ENL3
names: Similarity
messages: Belongs to the OCC1 family.

219594:LOC116499792
gene id: 219594:LOC116499792
uniprot id: A0A6J3EGR9
names: Similarity
messages: Belongs to the avian keratin family.

219594:C2H8orf37
gene id: 219594:C2H8orf37
uniprot id: A0A6J3CDG7
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: May be involved in photoreceptor outer segment disk morphogenesis.
messages: Photoreceptor inner segment

219594:WNT8A
gene id: 219594:WNT8A
uniprot id: A0A6J3DQL9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

219594:ING2
gene id: 219594:ING2
uniprot id: A0A6J3CVG4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ING family.
messages: Component of an histone acetyltransferase complex.
messages: Component of an histone acetyltransferase complex. Interacts with H3K4me3 and to a lesser extent with H3K4me2.
messages: Nucleus
messages: The PHD-type zinc finger mediates the binding to H3K4me3.

219594:FITM2
gene id: 219594:FITM2
uniprot id: A0A6J3DX33
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

219594:LOC116495326
gene id: 219594:LOC116495326
uniprot id: A0A6J3DUL2
names: Similarity
messages: Belongs to the mesothelin family.

219594:MANF
gene id: 219594:MANF
uniprot id: A0A6J3DES3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ARMET family.
messages: Secreted

219594:XRCC5
gene id: 219594:XRCC5
uniprot id: A0A6J3D467
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ku80 family.
messages: Nucleus
messages: Single-stranded DNA-dependent ATP-dependent helicase.

219594:ISL1
gene id: 219594:ISL1
uniprot id: A0A6J3EFB9
uniprot id: A0A6J3EIR6
names: Subcellular Location Annotation
messages: Nucleus

219594:ACMSD
gene id: 219594:ACMSD
uniprot id: A0A6J3D5B9
uniprot id: A0A6J3D7J4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. ACMSD family.
messages: Converts alpha-amino-beta-carboxymuconate-epsilon-semialdehyde (ACMS) to alpha-aminomuconate semialdehyde (AMS). ACMS can be converted non-enzymatically to quinolate (QA), a key precursor of NAD, and a potent endogenous excitotoxin of neuronal cells which is implicated in the pathogenesis of various neurodegenerative disorders. In the presence of ACMSD, ACMS is converted to AMS, a benign catabolite. ACMSD ultimately controls the metabolic fate of tryptophan catabolism along the kynurenine pathway.
messages: Monomer.

219594:WIF1
gene id: 219594:WIF1
uniprot id: A0A6J3DZ81
names: Caution
names: Function
messages: Binds to WNT proteins and inhibits their activities. May be involved in mesoderm segmentation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:KCTD20
gene id: 219594:KCTD20
uniprot id: A0A6J3E5U5
uniprot id: A0A6J3EAX5
names: Subcellular Location Annotation
messages: Cytoplasm

219594:RPP30
gene id: 219594:RPP30
uniprot id: A0A6J3DE40
names: Similarity
messages: Belongs to the eukaryotic/archaeal RNase P protein component 3 family.

219594:HMGCLL1
gene id: 219594:HMGCLL1
uniprot id: A0A6J3CTS1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HMG-CoA lyase family.
messages: Homodimer; disulfide-linked. Can also form homotetramers.
messages: Mitochondrial 3-hydroxymethyl-3-methylglutaryl-CoA lyase that catalyzes a cation-dependent cleavage of (S)-3-hydroxy-3-methylglutaryl-CoA into acetyl-CoA and acetoacetate, a key step in ketogenesis. Terminal step in leucine catabolism. Ketone bodies (beta-hydroxybutyrate, acetoacetate and acetone) are essential as an alternative source of energy to glucose, as lipid precursors and as regulators of metabolism.

219594:RIPK2
gene id: 219594:RIPK2
uniprot id: A0A6J3CJI6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family.
messages: Cytoplasm
messages: Found in a signaling complex consisting of at least ARHGEF2, NOD2 and RIPK2.
messages: Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains.

219594:PSMD5
gene id: 219594:PSMD5
uniprot id: A0A6J3E3X8
names: Similarity
messages: Belongs to the proteasome subunit S5B/HSM3 family.

219594:PPARGC1B
gene id: 219594:PPARGC1B
uniprot id: A0A6J3DTJ3
names: Subcellular Location Annotation
messages: Nucleus

219594:FOXG1
gene id: 219594:FOXG1
uniprot id: A0A6J3D241
names: Subcellular Location Annotation
messages: Nucleus

219594:LOC116488528
gene id: 219594:LOC116488528
uniprot id: A0A6J3CXM3
names: Subcellular Location Annotation
messages: Membrane

219594:TXNIP
gene id: 219594:TXNIP
uniprot id: A0A6J3EET4
names: Similarity
messages: Belongs to the arrestin family.

219594:EXOC3L1
gene id: 219594:EXOC3L1
uniprot id: A0A6J3DIF0
names: Similarity
messages: Belongs to the SEC6 family.

219594:RPL12
gene id: 219594:RPL12
uniprot id: A0A6J3E2L2
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Binds directly to 26S ribosomal RNA.

219594:LOC116489923
gene id: 219594:LOC116489923
uniprot id: A0A6J3D2E2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family.
messages: Secreted

219594:TXK
gene id: 219594:TXK
uniprot id: A0A6J3D115
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

219594:CCN6
gene id: 219594:CCN6
uniprot id: A0A6J3CQF8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCN family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

219594:DHRS7C
gene id: 219594:DHRS7C
uniprot id: A0A6J3DVW1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

219594:SERP1
gene id: 219594:SERP1
uniprot id: A0A6J3DJB9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RAMP4 family.
messages: Endoplasmic reticulum membrane
messages: May interact with target proteins during translocation into the lumen of the endoplasmic reticulum. May protect unfolded target proteins against degradation and facilitate correct glycosylation.
messages: Membrane

219594:GREB1L
gene id: 219594:GREB1L
uniprot id: A0A6J3CK55
uniprot id: A0A6J3CMS7
uniprot id: A0A6J3CPX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GREB1 family.
messages: Membrane

219594:HOXA9
gene id: 219594:HOXA9
uniprot id: A0A6J3CJC2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

219594:SS18L2
gene id: 219594:SS18L2
uniprot id: A0A6J3DPD5
names: Similarity
messages: Belongs to the SS18 family.

219594:TLE5
gene id: 219594:TLE5
uniprot id: A0A6J3E793
uniprot id: A0A6J3E8T3
uniprot id: A0A6J3ECC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat Groucho/TLE family.
messages: Nucleus

219594:BORCS8
gene id: 219594:BORCS8
uniprot id: A0A6J3E7C9
uniprot id: A0A6J3ECF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BORCS8 family.
messages: Lysosome membrane
messages: Membrane

219594:GALNT10
gene id: 219594:GALNT10
uniprot id: A0A6J3DM07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

219594:MPV17
gene id: 219594:MPV17
uniprot id: A0A6J3CPY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxisomal membrane protein PXMP2/4 family.
messages: Membrane

219594:NHEJ1
gene id: 219594:NHEJ1
uniprot id: A0A6J3D4X4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XRCC4-XLF family. XLF subfamily.
messages: Nucleus

219594:VPS8
gene id: 219594:VPS8
uniprot id: A0A6J3DBF3
uniprot id: A0A6J3DGY6
names: Similarity
messages: Belongs to the VPS8 family.

219594:TNFSF13B
gene id: 219594:TNFSF13B
uniprot id: A0A6J3EHI3
names: Similarity
messages: Belongs to the tumor necrosis factor family.

219594:PI4K2A
gene id: 219594:PI4K2A
uniprot id: A0A6J3D835
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PI3/PI4-kinase family. Type II PI4K subfamily.
messages: Membrane

219594:SENP1
gene id: 219594:SENP1
uniprot id: A0A6J3EEY2
names: Similarity
messages: Belongs to the peptidase C48 family.

219594:FMNL2
gene id: 219594:FMNL2
uniprot id: A0A6J3D2F4
uniprot id: A0A6J3D2F9
uniprot id: A0A6J3D4V5
uniprot id: A0A6J3D4W0
uniprot id: A0A6J3D4W5
uniprot id: A0A6J3D587
uniprot id: A0A6J3D588
uniprot id: A0A6J3D596
uniprot id: A0A6J3D7G2
uniprot id: A0A6J3D7G7
uniprot id: A0A6J3D8A9
names: Similarity
messages: Belongs to the formin homology family.

219594:NMNAT3
gene id: 219594:NMNAT3
uniprot id: A0A6J3DIT6
names: Similarity
messages: Belongs to the eukaryotic NMN adenylyltransferase family.

219594:TPR
gene id: 219594:TPR
uniprot id: A0A6J3DDV7
uniprot id: A0A6J3DEZ6
uniprot id: A0A6J3DH79
names: Similarity
messages: Belongs to the TPR family.

219594:TMC6
gene id: 219594:TMC6
uniprot id: A0A6J3DY89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMC family.
messages: Membrane

219594:ATG4B
gene id: 219594:ATG4B
uniprot id: A0A6J3DFI2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C54 family.
messages: Cysteine protease that plays a key role in autophagy by mediating both proteolytic activation and delipidation of ATG8 family proteins.
messages: Endoplasmic reticulum
messages: Mitochondrion
messages: autophagosome
messages: cytosol

219594:LOC116496139
gene id: 219594:LOC116496139
uniprot id: A0A6J3DZA1
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

219594:EIF2B2
gene id: 219594:EIF2B2
uniprot id: A0A6J3D1J1
names: Similarity
messages: Belongs to the eIF-2B alpha/beta/delta subunits family.

219594:LOC116486814
gene id: 219594:LOC116486814
uniprot id: A0A6J3CJN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Endoplasmic reticulum membrane

219594:SLC12A3
gene id: 219594:SLC12A3
uniprot id: A0A6J3DJH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC12A transporter family.
messages: Membrane

219594:CDKN1B
gene id: 219594:CDKN1B
uniprot id: A0A6J3EJ09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDI family.
messages: Cytoplasm
messages: Endosome
messages: Nucleus

219594:MRAP
gene id: 219594:MRAP
uniprot id: A0A6J3EJ73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MRAP family.
messages: Endoplasmic reticulum membrane
messages: Membrane

219594:EPB42
gene id: 219594:EPB42
uniprot id: A0A6J3DXI9
names: Similarity
messages: Belongs to the transglutaminase superfamily. Transglutaminase family.

219594:LOC116486658
gene id: 219594:LOC116486658
uniprot id: A0A6J3CNK2
names: Similarity
names: Subunit
messages: Belongs to the avian keratin family.
messages: The avian keratins (F-ker, S-ker, C-ker and B-ker) are a complex mixture of very similar polypeptides.

219594:PEX14
gene id: 219594:PEX14
uniprot id: A0A6J3E2S5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxin-14 family.
messages: Component of the peroxisomal translocation machinery.
messages: Peroxisome membrane

219594:NPNT
gene id: 219594:NPNT
uniprot id: A0A6J3CXN4
uniprot id: A0A6J3CY00
uniprot id: A0A6J3D0A0
uniprot id: A0A6J3D1F5
names: Caution
names: Similarity
messages: Belongs to the nephronectin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:GREM2
gene id: 219594:GREM2
uniprot id: A0A6J3CRW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DAN family.
messages: Secreted

219594:LOC116497003
gene id: 219594:LOC116497003
uniprot id: A0A6J3E3E8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

219594:SH3BP5
gene id: 219594:SH3BP5
uniprot id: A0A6J3CNY8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SH3BP5 family.
messages: Cytoplasm
messages: Functions as guanine nucleotide exchange factor (GEF) for RAB11A.
messages: Interacts with GDP-bound and nucleotide-free forms of RAB11A.
messages: The N-terminal half of the protein mediates interaction with RAB11A and functions as guanine nucleotide exchange factor. Four long alpha-helices (interrupted by a central kink) assemble into coiled coils, giving rise to a 'V' shape.

219594:TPO
gene id: 219594:TPO
uniprot id: A0A6J3CRX0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the prostaglandin G/H synthase family.
messages: Interacts with DUOX1, DUOX2 and CYBA.
messages: Iodination and coupling of the hormonogenic tyrosines in thyroglobulin to yield the thyroid hormones T(3) and T(4).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

219594:GRPR
gene id: 219594:GRPR
uniprot id: A0A6J3EI70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:HTR2A
gene id: 219594:HTR2A
uniprot id: A0A6J3E6P2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Cytoplasmic vesicle
messages: G-protein coupled receptor for 5-hydroxytryptamine (serotonin).
messages: Membrane
messages: Presynapse
messages: Synapse
messages: Vesicle
messages: axon
messages: caveola
messages: dendrite

219594:STIM1
gene id: 219594:STIM1
uniprot id: A0A6J3DHE6
uniprot id: A0A6J3DHF8
uniprot id: A0A6J3DK10
uniprot id: A0A6J3DK22
uniprot id: A0A6J3DLK0
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

219594:SNAPIN
gene id: 219594:SNAPIN
uniprot id: A0A6J3EE35
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNAPIN family.
messages: Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. Plays a role in intracellular vesicle trafficking and synaptic vesicle recycling.
messages: synaptic vesicle membrane

219594:BNIP3L
gene id: 219594:BNIP3L
uniprot id: A0A6J3EF61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NIP3 family.
messages: Membrane

219594:RPAP1
gene id: 219594:RPAP1
uniprot id: A0A6J3D0W1
uniprot id: A0A6J3D3J0
names: Similarity
messages: Belongs to the RPAP1 family.

219594:VTI1A
gene id: 219594:VTI1A
uniprot id: A0A6J3D7N9
uniprot id: A0A6J3DB33
uniprot id: A0A6J3DD97
uniprot id: A0A6J3DDM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VTI1 family.
messages: Membrane

219594:GRB14
gene id: 219594:GRB14
uniprot id: A0A6J3D634
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GRB7/10/14 family.
messages: Cytoplasm

219594:FER
gene id: 219594:FER
uniprot id: A0A6J3EEK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily.
messages: cytoskeleton

219594:SUSD3
gene id: 219594:SUSD3
uniprot id: A0A6J3DLG9
uniprot id: A0A6J3DLZ1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:PRKAR1A
gene id: 219594:PRKAR1A
uniprot id: A0A6J3E1Z0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cAMP-dependent kinase regulatory chain family.
messages: Cell membrane
messages: Membrane

219594:LOC116498281
gene id: 219594:LOC116498281
uniprot id: A0A6J3E948
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gastrin/cholecystokinin family.
messages: Secreted

219594:MAP7D3
gene id: 219594:MAP7D3
uniprot id: A0A6J3DP42
uniprot id: A0A6J3DR22
names: Similarity
messages: Belongs to the MAP7 family.

219594:CLDN5
gene id: 219594:CLDN5
uniprot id: A0A6J3DUW4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

219594:USP10
gene id: 219594:USP10
uniprot id: A0A6J3DPB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C19 family. USP10 subfamily.
messages: Cytoplasm
messages: Nucleus

219594:COPZ2
gene id: 219594:COPZ2
uniprot id: A0A6J3E423
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adaptor complexes small subunit family.
messages: COPI-coated vesicle membrane
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.
messages: The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properties with the coatomer complex.

219594:ARID5B
gene id: 219594:ARID5B
uniprot id: A0A6J3D6E7
uniprot id: A0A6J3D9P8
uniprot id: A0A6J3DBW8
uniprot id: A0A6J3DCD1
names: Similarity
messages: Belongs to the ARID5B family.

219594:NDUFA7
gene id: 219594:NDUFA7
uniprot id: A0A6J3E7A3
names: Function
names: Similarity
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFA7 subunit family.
messages: Complex I is composed of 45 different subunits.

219594:STAT4
gene id: 219594:STAT4
uniprot id: A0A6J3D6L0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transcription factor STAT family.
messages: Cytoplasm
messages: Nucleus

219594:CUX1
gene id: 219594:CUX1
uniprot id: A0A6J3DZC0
uniprot id: A0A6J3E0X0
uniprot id: A0A6J3E4E6
uniprot id: A0A6J3E4F5
uniprot id: A0A6J3E5F2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CASP family.
messages: Belongs to the CUT homeobox family.
messages: Golgi apparatus membrane
messages: Membrane
messages: Nucleus

219594:LOC116486352
gene id: 219594:LOC116486352
uniprot id: A0A6J3CHD9
names: Similarity
messages: Belongs to the serpin family.

219594:LOC116493439
gene id: 219594:LOC116493439
uniprot id: A0A6J3DMH2
uniprot id: A0A6J3DN19
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adaptor complexes small subunit family.
messages: Cytoplasmic vesicle membrane
messages: Membrane
messages: Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals.

219594:SLC35F6
gene id: 219594:SLC35F6
uniprot id: A0A6J3CQM6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SLC35F solute transporter family.
messages: Interacts with SLC25A5.
messages: May play a role as a nucleotide-sugar transporter.
messages: Membrane
messages: Mitochondrion

219594:ST8SIA6
gene id: 219594:ST8SIA6
uniprot id: A0A6J3CK59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

219594:NKX2-4
gene id: 219594:NKX2-4
uniprot id: A0A6J3CT50
names: Subcellular Location Annotation
messages: Nucleus

219594:C11H15orf65
gene id: 219594:C11H15orf65
uniprot id: A0A6J3DNG3
names: Subcellular Location Annotation
messages: cilium axoneme

219594:SSTR5
gene id: 219594:SSTR5
uniprot id: A0A6J3DVM3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:OSBPL11
gene id: 219594:OSBPL11
uniprot id: A0A6J3D3J7
names: Similarity
messages: Belongs to the OSBP family.

219594:TMPRSS7
gene id: 219594:TMPRSS7
uniprot id: A0A6J3EHG3
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

219594:SCAMP1
gene id: 219594:SCAMP1
uniprot id: A0A6J3EGD8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCAMP family.
messages: Membrane

219594:TAF1B
gene id: 219594:TAF1B
uniprot id: A0A6J3CWF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRN7/TAF1B family.
messages: nucleolus

219594:TACR3
gene id: 219594:TACR3
uniprot id: A0A6J3CXC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:TSPAN5
gene id: 219594:TSPAN5
uniprot id: A0A6J3CS59
uniprot id: A0A6J3CX83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

219594:KARS1
gene id: 219594:KARS1
uniprot id: A0A6J3DJ77
uniprot id: A0A6J3DNE0
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.

219594:POU2F1
gene id: 219594:POU2F1
uniprot id: A0A6J3EJU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POU transcription factor family. Class-2 subfamily.
messages: Nucleus

219594:SVEP1
gene id: 219594:SVEP1
uniprot id: A0A6J3EF47
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

219594:ACVR1C
gene id: 219594:ACVR1C
uniprot id: A0A6J3D4A9
uniprot id: A0A6J3D6Z0
uniprot id: A0A6J3D7H3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Membrane

219594:FOXI3
gene id: 219594:FOXI3
uniprot id: A0A6J3D064
names: Subcellular Location Annotation
messages: Nucleus

219594:LOC116486271
gene id: 219594:LOC116486271
uniprot id: A0A6J3CN28
names: Similarity
messages: Belongs to the SELO family.

219594:LOC116496247
gene id: 219594:LOC116496247
uniprot id: A0A6J3DWI1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferrin family.
messages: Monomer.
messages: Secreted

219594:RSAD1
gene id: 219594:RSAD1
uniprot id: A0A6J3E1P4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: May be a heme chaperone, appears to bind heme. Homologous bacterial proteins do not have oxygen-independent coproporphyrinogen-III oxidase activity. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Mitochondrion

219594:LOC116498589
gene id: 219594:LOC116498589
uniprot id: A0A6J3E9P0
names: Similarity
names: Subunit
messages: Belongs to the avian keratin family.
messages: The avian keratins (F-ker, S-ker, C-ker and B-ker) are a complex mixture of very similar polypeptides.

219594:SEPTIN3
gene id: 219594:SEPTIN3
uniprot id: A0A6J3DPC5
uniprot id: A0A6J3DPD6
uniprot id: A0A6J3DS95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
messages: Cytoplasm

219594:EIPR1
gene id: 219594:EIPR1
uniprot id: A0A6J3CR32
names: Similarity
messages: Belongs to the WD repeat EIPR1 family.

219594:NUP107
gene id: 219594:NUP107
uniprot id: A0A6J3EBT2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nucleoporin Nup84/Nup107 family.
messages: Functions as a component of the nuclear pore complex (NPC).
messages: Nucleus membrane
messages: Part of the nuclear pore complex (NPC).
messages: nuclear pore complex

219594:TTC21B
gene id: 219594:TTC21B
uniprot id: A0A6J3D5Q0
names: Similarity
messages: Belongs to the TTC21 family.

219594:GPR152
gene id: 219594:GPR152
uniprot id: A0A6J3D067
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

219594:CPSF2
gene id: 219594:CPSF2
uniprot id: A0A6J3D4E3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. CPSF2/YSH1 subfamily.
messages: Nucleus

219594:LOC116498949
gene id: 219594:LOC116498949
uniprot id: A0A6J3E884
names: Subcellular Location Annotation
messages: mitochondrion nucleoid

219594:PMPCA
gene id: 219594:PMPCA
uniprot id: A0A6J3E1Q7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase M16 family.
messages: Heterodimer of PMPCA (alpha) and PMPCB (beta) subunits, forming the mitochondrial processing protease (MPP) in which PMPCA is involved in substrate recognition and binding and PMPCB is the catalytic subunit.
messages: Membrane
messages: Mitochondrion inner membrane
messages: Mitochondrion matrix
messages: Substrate recognition and binding subunit of the essential mitochondrial processing protease (MPP), which cleaves the mitochondrial sequence off newly imported precursors proteins.

219594:PSMC3
gene id: 219594:PSMC3
uniprot id: A0A6J3D0Y5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family.
messages: Cytoplasm
messages: Nucleus

219594:ANO4
gene id: 219594:ANO4
uniprot id: A0A6J3CBU7
uniprot id: A0A6J3CEH4
uniprot id: A0A6J3CEI8
uniprot id: A0A6J3CG97
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anoctamin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

219594:DIPK2B
gene id: 219594:DIPK2B
uniprot id: A0A6J3EPG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DIPK family.
messages: Secreted

219594:SOX14
gene id: 219594:SOX14
uniprot id: A0A6J3DDS6
names: Subcellular Location Annotation
messages: Nucleus

219594:ANKRD17
gene id: 219594:ANKRD17
uniprot id: A0A6J3CYA3
names: Subcellular Location Annotation
messages: Cytoplasm

219594:PRDM14
gene id: 219594:PRDM14
uniprot id: A0A6J3CDF7
names: Subcellular Location Annotation
messages: Nucleus

219594:IRF5
gene id: 219594:IRF5
uniprot id: A0A6J3E6K5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IRF family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

219594:LYRM2
gene id: 219594:LYRM2
uniprot id: A0A6J3CQK4
names: Similarity
messages: Belongs to the complex I LYR family.

219594:GTF2F2
gene id: 219594:GTF2F2
uniprot id: A0A6J3DR02
uniprot id: A0A6J3DUS8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFIIF beta subunit family.
messages: Nucleus
messages: TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB.

219594:SLC27A4
gene id: 219594:SLC27A4
uniprot id: A0A6J3E2P0
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

219594:TRH
gene id: 219594:TRH
uniprot id: A0A6J3DIJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRH family.
messages: Functions as a regulator of the biosynthesis of TSH in the anterior pituitary gland and as a neurotransmitter/ neuromodulator in the central and peripheral nervous systems.
messages: Secreted

219594:RBPJL
gene id: 219594:RBPJL
uniprot id: A0A6J3DUL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Su(H) family.
messages: Nucleus

219594:FOXA1
gene id: 219594:FOXA1
uniprot id: A0A6J3D770
names: Subcellular Location Annotation
messages: Nucleus

219594:CAPRIN2
gene id: 219594:CAPRIN2
uniprot id: A0A6J3D131
uniprot id: A0A6J3D3G1
uniprot id: A0A6J3D3Q3
uniprot id: A0A6J3D6Y9
names: Similarity
messages: Belongs to the caprin family.

219594:MAK16
gene id: 219594:MAK16
uniprot id: A0A6J3EFK8
names: Similarity
messages: Belongs to the MAK16 family.

219594:MEGF10
gene id: 219594:MEGF10
uniprot id: A0A6J3ELN5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:HMGA1
gene id: 219594:HMGA1
uniprot id: A0A6J3E875
uniprot id: A0A6J3EB81
uniprot id: A0A6J3EDD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HMGA family.
messages: Nucleus

219594:GNGT2
gene id: 219594:GNGT2
uniprot id: A0A6J3E541
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G protein gamma family.
messages: Cell membrane
messages: G proteins are composed of 3 units; alpha, beta and gamma.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

219594:DNAAF6
gene id: 219594:DNAAF6
uniprot id: A0A6J3DL22
names: Similarity
messages: Belongs to the PIH1 family.

219594:MACF1
gene id: 219594:MACF1
uniprot id: A0A6J3E329
names: Subcellular Location Annotation
messages: cytoskeleton

219594:PGAP2
gene id: 219594:PGAP2
uniprot id: A0A6J3DT29
uniprot id: A0A6J3DT51
uniprot id: A0A6J3DW35
uniprot id: A0A6J3DWZ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PGAP2 family.
messages: Involved in the lipid remodeling steps of GPI-anchor maturation. Required for stable expression of GPI-anchored proteins at the cell surface.
messages: Membrane

219594:GGA2
gene id: 219594:GGA2
uniprot id: A0A6J3DX96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GGA protein family.
messages: Early endosome membrane
messages: Endosome membrane
messages: trans-Golgi network membrane

219594:PCYOX1
gene id: 219594:PCYOX1
uniprot id: A0A6J3EF08
names: Similarity
messages: Belongs to the prenylcysteine oxidase family.

219594:PNLDC1
gene id: 219594:PNLDC1
uniprot id: A0A6J3CR54
uniprot id: A0A6J3CRU1
names: Similarity
messages: Belongs to the CAF1 family.

219594:BTAF1
gene id: 219594:BTAF1
uniprot id: A0A6J3D8Y5
names: Subcellular Location Annotation
messages: Nucleus

219594:MACIR
gene id: 219594:MACIR
uniprot id: A0A6J3ELW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UNC119-binding protein family.
messages: Cytoplasm
messages: cilium

219594:LOC116486457
gene id: 219594:LOC116486457
uniprot id: A0A6J3CP19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cathelicidin family.
messages: Secreted

219594:SPECC1L
gene id: 219594:SPECC1L
uniprot id: A0A6J3DU82
uniprot id: A0A6J3DZ34
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytospin-A family.
messages: Involved in cytokinesis and spindle organization. May play a role in actin cytoskeleton organization and microtubule stabilization and hence required for proper cell adhesion and migration.
messages: May interact with both microtubules and actin cytoskeleton.
messages: cytoskeleton
messages: gap junction
messages: spindle

219594:MFAP5
gene id: 219594:MFAP5
uniprot id: A0A6J3DG92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MFAP family.
messages: extracellular matrix

219594:WNT9A
gene id: 219594:WNT9A
uniprot id: A0A6J3CIH2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

219594:GALNT2
gene id: 219594:GALNT2
uniprot id: A0A6J3CLL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

219594:LOC116499895
gene id: 219594:LOC116499895
uniprot id: A0A6J3EH22
names: Similarity
messages: Belongs to the intermediate filament family.

219594:TRPV3
gene id: 219594:TRPV3
uniprot id: A0A6J3DZ63
names: Subcellular Location Annotation
messages: Membrane

219594:ADHFE1
gene id: 219594:ADHFE1
uniprot id: A0A6J3CL67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the iron-containing alcohol dehydrogenase family. Hydroxyacid-oxoacid transhydrogenase subfamily.
messages: Mitochondrion

219594:ATP7B
gene id: 219594:ATP7B
uniprot id: A0A6J3ER03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Membrane
messages: trans-Golgi network membrane

219594:NTMT1
gene id: 219594:NTMT1
uniprot id: A0A6J3DZF7
names: Similarity
messages: Belongs to the methyltransferase superfamily. NTM1 family.

219594:FAM160A2
gene id: 219594:FAM160A2
uniprot id: A0A6J3EK61
names: Similarity
messages: Belongs to the FHIP family.

219594:SEC31A
gene id: 219594:SEC31A
uniprot id: A0A6J3CTE8
uniprot id: A0A6J3CVR2
uniprot id: A0A6J3CVR6
uniprot id: A0A6J3CW67
uniprot id: A0A6J3CYI1
uniprot id: A0A6J3CZK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat SEC31 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

219594:TEF
gene id: 219594:TEF
uniprot id: A0A6J3E6K7
uniprot id: A0A6J3EB55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. PAR subfamily.
messages: Nucleus

219594:RPL24
gene id: 219594:RPL24
uniprot id: A0A6J3D1I2
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL24 family.

219594:CALCB
gene id: 219594:CALCB
uniprot id: A0A6J3D4P5
uniprot id: A0A6J3D6X5
uniprot id: A0A6J3D7R9
names: Similarity
messages: Belongs to the calcitonin family.

219594:LOC116492561
gene id: 219594:LOC116492561
uniprot id: A0A6J3DFC8
uniprot id: A0A6J3DI71
names: Similarity
messages: Belongs to the eukaryotic diacylglycerol kinase family.

219594:LOC116488042
gene id: 219594:LOC116488042
uniprot id: A0A6J3CSW7
names: Similarity
messages: Belongs to the GST superfamily. Alpha family.

219594:TMEM35A
gene id: 219594:TMEM35A
uniprot id: A0A6J3DRX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Peroxisome membrane
messages: Vesicle

219594:KMT5B
gene id: 219594:KMT5B
uniprot id: A0A6J3D417
names: Subcellular Location Annotation
messages: Chromosome
messages: Nucleus

219594:CLCN7
gene id: 219594:CLCN7
uniprot id: A0A6J3DT09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel (TC 2.A.49) family.
messages: Membrane

219594:SNX25
gene id: 219594:SNX25
uniprot id: A0A6J3CZZ0
uniprot id: A0A6J3D132
names: Similarity
messages: Belongs to the sorting nexin family.

219594:PLXNA1
gene id: 219594:PLXNA1
uniprot id: A0A6J3DGZ8
uniprot id: A0A6J3DJV4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the plexin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

219594:KCNS2
gene id: 219594:KCNS2
uniprot id: A0A6J3CLJ2
names: Subcellular Location Annotation
messages: Membrane

219594:NIFK
gene id: 219594:NIFK
uniprot id: A0A6J3D3Y0
names: Subcellular Location Annotation
messages: nucleolus

219594:TNKS
gene id: 219594:TNKS
uniprot id: A0A6J3D0K1
names: Similarity
messages: Belongs to the ARTD/PARP family.

219594:LOC116500130
gene id: 219594:LOC116500130
uniprot id: A0A6J3EFX7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:IER5L
gene id: 219594:IER5L
uniprot id: A0A6J3DZK0
names: Similarity
messages: Belongs to the IER family.

219594:PTH1R
gene id: 219594:PTH1R
uniprot id: A0A6J3CP98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family.
messages: Cell membrane
messages: Membrane

219594:LMF1
gene id: 219594:LMF1
uniprot id: A0A6J3DWQ8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lipase maturation factor family.
messages: Endoplasmic reticulum membrane
messages: Involved in the maturation of specific proteins in the endoplasmic reticulum.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

219594:TUBG1
gene id: 219594:TUBG1
uniprot id: A0A6J3E6R6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules. The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome.
messages: centrosome

219594:LOC116498322
gene id: 219594:LOC116498322
uniprot id: A0A6J3E979
names: Similarity
names: Subunit
messages: Belongs to the avian keratin family.
messages: The avian keratins (F-ker, S-ker, C-ker and B-ker) are a complex mixture of very similar polypeptides.

219594:NME6
gene id: 219594:NME6
uniprot id: A0A6J3EL01
names: Similarity
messages: Belongs to the NDK family.

219594:TARS1
gene id: 219594:TARS1
uniprot id: A0A6J3EL99
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.

219594:LACTB2
gene id: 219594:LACTB2
uniprot id: A0A6J3CKH7
names: Function
names: Similarity
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
messages: Endoribonuclease; cleaves preferentially 3' to purine-pyrimidine dinucleotide motifs in single-stranded RNA. The cleavage product contains a free 3' -OH group. Has no activity with double-stranded RNA or DNA. Required for normal mitochondrial function and cell viability.

219594:CLIC6
gene id: 219594:CLIC6
uniprot id: A0A6J3EIW6
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel CLIC family.
messages: Cytoplasm
messages: Members of this family may change from a globular, soluble state to a state where the N-terminal domain is inserted into the membrane and functions as chloride channel. A conformation change of the N-terminal domain is thought to expose hydrophobic surfaces that trigger membrane insertion.
messages: Membrane

219594:BCL9
gene id: 219594:BCL9
uniprot id: A0A6J3EGA6
uniprot id: A0A6J3EGB9
uniprot id: A0A6J3EGC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BCL9 family.
messages: Nucleus

219594:MYOC
gene id: 219594:MYOC
uniprot id: A0A6J3DGE2
names: Caution
names: Subcellular Location Annotation
messages: Endoplasmic reticulum
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Mitochondrion intermembrane space
messages: Mitochondrion outer membrane
messages: Rough endoplasmic reticulum
messages: cilium
messages: extracellular exosome
messages: extracellular space

219594:LOC116501450
gene id: 219594:LOC116501450
uniprot id: A0A6J3EI85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:LOC116494479
gene id: 219594:LOC116494479
uniprot id: A0A6J3DQM8
names: Similarity
messages: Belongs to the SUA5 family.

219594:TACC1
gene id: 219594:TACC1
uniprot id: A0A6J3E9U2
uniprot id: A0A6J3ED06
uniprot id: A0A6J3EDF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACC family.
messages: Cytoplasm

219594:PRDM15
gene id: 219594:PRDM15
uniprot id: A0A6J3DID2
uniprot id: A0A6J3DKY9
uniprot id: A0A6J3DML0
uniprot id: A0A6J3DNW3
names: Subcellular Location Annotation
messages: Nucleus

219594:MAPK10
gene id: 219594:MAPK10
uniprot id: A0A6J3CVW8
uniprot id: A0A6J3CY66
uniprot id: A0A6J3CY73
uniprot id: A0A6J3CYI5
uniprot id: A0A6J3CYJ3
uniprot id: A0A6J3D0S3
uniprot id: A0A6J3D0T2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.
messages: Cytoplasm
messages: Responds to activation by environmental stress and pro-inflammatory cytokines by phosphorylating a number of transcription factors, and thus regulates transcriptional activity.

219594:LOC116492020
gene id: 219594:LOC116492020
uniprot id: A0A6J3DFX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FMO family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Microsome membrane

219594:LOC116492438
gene id: 219594:LOC116492438
uniprot id: A0A6J3DCB9
names: Similarity
messages: Belongs to the CD200R family.

219594:GJA10
gene id: 219594:GJA10
uniprot id: A0A6J3CP10
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

219594:RAB29
gene id: 219594:RAB29
uniprot id: A0A6J3ECR0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Membrane
messages: The small GTPases Rab are key regulators in vesicle trafficking.

219594:USO1
gene id: 219594:USO1
uniprot id: A0A6J3CSM6
uniprot id: A0A6J3CUY8
uniprot id: A0A6J3CYT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VDP/USO1/EDE1 family.
messages: Membrane

219594:FUBP3
gene id: 219594:FUBP3
uniprot id: A0A6J3DXV4
uniprot id: A0A6J3E218
uniprot id: A0A6J3E2V8
names: Subcellular Location Annotation
messages: Cytoplasm

219594:LOC116489472
gene id: 219594:LOC116489472
uniprot id: A0A6J3D007
names: Similarity
messages: Belongs to the splicing factor SR family.

219594:SNRPA1
gene id: 219594:SNRPA1
uniprot id: A0A6J3DKW3
names: Similarity
messages: Belongs to the U2 small nuclear ribonucleoprotein A family.

219594:CCDC149
gene id: 219594:CCDC149
uniprot id: A0A6J3CVM5
uniprot id: A0A6J3CXX4
uniprot id: A0A6J3D1P1
names: Similarity
messages: Belongs to the CCDC149 family.

219594:HOXD3
gene id: 219594:HOXD3
uniprot id: A0A6J3D6V5
uniprot id: A0A6J3D7E0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus

219594:KCTD10
gene id: 219594:KCTD10
uniprot id: A0A6J3DTX8
uniprot id: A0A6J3DY26
names: Similarity
messages: Belongs to the BACURD family.

219594:BRPF3
gene id: 219594:BRPF3
uniprot id: A0A6J3ED87
names: Subcellular Location Annotation
messages: Nucleus

219594:TRPM8
gene id: 219594:TRPM8
uniprot id: A0A6J3D2T7
uniprot id: A0A6J3D5M3
uniprot id: A0A6J3D8P4
names: Subcellular Location Annotation
messages: Membrane

219594:EMC3
gene id: 219594:EMC3
uniprot id: A0A6J3DJR6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EMC3 family.
messages: Component of the ER membrane protein complex (EMC).
messages: Membrane

219594:LOC116486698
gene id: 219594:LOC116486698
uniprot id: A0A6J3CNS0
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS7 family.

219594:SBK1
gene id: 219594:SBK1
uniprot id: A0A6J3DQT0
uniprot id: A0A6J3DV60
uniprot id: A0A6J3DW14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
messages: Cytoplasm

219594:PPDPFL
gene id: 219594:PPDPFL
uniprot id: A0A6J3CJE1
names: Similarity
messages: Belongs to the PPDPF family.

219594:SCRN1
gene id: 219594:SCRN1
uniprot id: A0A6J3CND3
names: Similarity
messages: Belongs to the peptidase C69 family. Secernin subfamily.

219594:STOML1
gene id: 219594:STOML1
uniprot id: A0A6J3DI49
uniprot id: A0A6J3DMA0
names: Similarity
messages: Belongs to the band 7/mec-2 family.

219594:LOC116491423
gene id: 219594:LOC116491423
uniprot id: A0A6J3D737
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UDP-glycosyltransferase family.
messages: Membrane

219594:LOC116499744
gene id: 219594:LOC116499744
uniprot id: A0A6J3EE50
names: Similarity
names: Subunit
messages: Belongs to the avian keratin family.
messages: The avian keratins (F-ker, S-ker, C-ker and B-ker) are a complex mixture of very similar polypeptides.

219594:TMEM218
gene id: 219594:TMEM218
uniprot id: A0A6J3E1Y9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM218 family.
messages: May be involved in ciliary biogenesis or function.
messages: Membrane
messages: cilium

219594:LOC116499643
gene id: 219594:LOC116499643
uniprot id: A0A6J3E9H2
names: Similarity
names: Subunit
messages: Belongs to the avian keratin family.
messages: The avian keratins (F-ker, S-ker, C-ker and B-ker) are a complex mixture of very similar polypeptides.

219594:FKBP6
gene id: 219594:FKBP6
uniprot id: A0A6J3E6B9
names: Function
names: Similarity
messages: Belongs to the FKBP6 family.
messages: Co-chaperone required during spermatogenesis to repress transposable elements and prevent their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent repression of transposons. Acts as a co-chaperone via its interaction with HSP90 and is required for the piRNA amplification process, the secondary piRNA biogenesis. May be required together with HSP90 in removal of 16 nucleotide ping-pong by-products from Piwi complexes, possibly facilitating turnover of Piwi complexes.

219594:TMC7
gene id: 219594:TMC7
uniprot id: A0A6J3DTB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMC family.
messages: Membrane

219594:NR2F2
gene id: 219594:NR2F2
uniprot id: A0A6J3DGX3
uniprot id: A0A6J3DMG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

219594:LOC116490045
gene id: 219594:LOC116490045
uniprot id: A0A6J3D0G2
uniprot id: A0A6J3D5F0
uniprot id: A0A6J3D6C6
names: Similarity
messages: Belongs to the actin family.

219594:LOC116492543
gene id: 219594:LOC116492543
uniprot id: A0A6J3DGG7
names: Similarity
messages: Belongs to the cytochrome P450 family.

219594:FLI1
gene id: 219594:FLI1
uniprot id: A0A6J3E2M9
uniprot id: A0A6J3E427
uniprot id: A0A6J3E6X6
uniprot id: A0A6J3E7M2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

219594:NT5C3B
gene id: 219594:NT5C3B
uniprot id: A0A6J3EAA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrimidine 5'-nucleotidase family.
messages: Cytoplasm

219594:ESCO1
gene id: 219594:ESCO1
uniprot id: A0A6J3CPY5
names: Subcellular Location Annotation
messages: Nucleus

219594:LOC116492695
gene id: 219594:LOC116492695
uniprot id: A0A6J3DG00
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

219594:CSNK1G2
gene id: 219594:CSNK1G2
uniprot id: A0A6J3E7K4
uniprot id: A0A6J3E937
names: Similarity
messages: Belongs to the protein kinase superfamily. CK1 Ser/Thr protein kinase family. Casein kinase I subfamily.

219594:MAP6
gene id: 219594:MAP6
uniprot id: A0A6J3EQN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STOP family.
messages: cytoskeleton

219594:ATP6V1E1
gene id: 219594:ATP6V1E1
uniprot id: A0A6J3ENB3
names: Similarity
messages: Belongs to the V-ATPase E subunit family.

219594:AKT1
gene id: 219594:AKT1
uniprot id: A0A6J3D149
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. RAC subfamily.

219594:HCK
gene id: 219594:HCK
uniprot id: A0A6J3DXS4
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

219594:TXNRD3
gene id: 219594:TXNRD3
uniprot id: A0A6J3DEL3
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

219594:SSR3
gene id: 219594:SSR3
uniprot id: A0A6J3DGD2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP-gamma family.
messages: Endoplasmic reticulum membrane
messages: Heterotetramer of TRAP-alpha, TRAP-beta, TRAP-delta and TRAP-gamma.
messages: Membrane
messages: TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins.

219594:FSCN2
gene id: 219594:FSCN2
uniprot id: A0A6J3E0V4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fascin family.
messages: cytoskeleton

219594:CAP1
gene id: 219594:CAP1
uniprot id: A0A6J3E800
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CAP family.
messages: Cell membrane
messages: Directly regulates filament dynamics and has been implicated in a number of complex developmental and morphological processes, including mRNA localization and the establishment of cell polarity.
messages: Homodimer. Binds actin monomers.
messages: Membrane

219594:LOC116491973
gene id: 219594:LOC116491973
uniprot id: A0A6J3DFQ2
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

219594:COPS4
gene id: 219594:COPS4
uniprot id: A0A6J3CXV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSN4 family.
messages: Nucleus
messages: Vesicle
messages: synaptic vesicle

219594:AQP4
gene id: 219594:AQP4
uniprot id: A0A6J3CC98
uniprot id: A0A6J3CIJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

219594:ADAM23
gene id: 219594:ADAM23
uniprot id: A0A6J3D8P5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:UVSSA
gene id: 219594:UVSSA
uniprot id: A0A6J3CV85
names: Similarity
messages: Belongs to the UVSSA family.

219594:SEC22A
gene id: 219594:SEC22A
uniprot id: A0A6J3DB11
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Endoplasmic reticulum membrane
messages: May be involved in vesicle transport between the ER and the Golgi complex.
messages: Membrane

219594:LOC116496366
gene id: 219594:LOC116496366
uniprot id: A0A6J3DVA7
names: Similarity
messages: Belongs to the GST superfamily. Theta family.

219594:SLC25A3
gene id: 219594:SLC25A3
uniprot id: A0A6J3EJ86
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Interacts with PPIF; the interaction is impaired by CsA.
messages: Membrane
messages: Mitochondrion inner membrane

219594:KAT2A
gene id: 219594:KAT2A
uniprot id: A0A6J3E6M9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetyltransferase family. GCN5 subfamily.
messages: Nucleus
messages: centrosome

219594:CD180
gene id: 219594:CD180
uniprot id: A0A6J3EE43
names: Similarity
messages: Belongs to the Toll-like receptor family.

219594:PTS
gene id: 219594:PTS
uniprot id: A0A6J3E6M5
names: Function
names: Similarity
messages: Belongs to the PTPS family.
messages: Involved in the biosynthesis of tetrahydrobiopterin, an essential cofactor of aromatic amino acid hydroxylases. Catalyzes the transformation of 7,8-dihydroneopterin triphosphate into 6-pyruvoyl tetrahydropterin.

219594:RPL3
gene id: 219594:RPL3
uniprot id: A0A6J3EB35
names: Similarity
messages: Belongs to the universal ribosomal protein uL3 family.

219594:SLC51A
gene id: 219594:SLC51A
uniprot id: A0A6J3DBC1
names: Subcellular Location Annotation
messages: Membrane

219594:FZR1
gene id: 219594:FZR1
uniprot id: A0A6J3E953
names: Similarity
messages: Belongs to the WD repeat CDC20/Fizzy family.

219594:MRPS27
gene id: 219594:MRPS27
uniprot id: A0A6J3EKZ8
names: Subcellular Location Annotation
messages: Mitochondrion

219594:KCNQ4
gene id: 219594:KCNQ4
uniprot id: A0A6J3E5G4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

219594:MTRF1
gene id: 219594:MTRF1
uniprot id: A0A6J3DLP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Mitochondrion

219594:STAT3
gene id: 219594:STAT3
uniprot id: A0A6J3E650
uniprot id: A0A6J3E9R4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transcription factor STAT family.
messages: Cytoplasm
messages: Nucleus

219594:COQ3
gene id: 219594:COQ3
uniprot id: A0A6J3CW96
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family.
messages: Component of a multi-subunit COQ enzyme complex, composed of at least COQ3, COQ4, COQ5, COQ6, COQ7 and COQ9.
messages: Mitochondrion inner membrane
messages: O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.

219594:SPSB1
gene id: 219594:SPSB1
uniprot id: A0A6J3E309
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPSB family.
messages: Cytoplasm

219594:TMC2
gene id: 219594:TMC2
uniprot id: A0A6J3CFX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMC family.
messages: Membrane

219594:USP5
gene id: 219594:USP5
uniprot id: A0A6J3DU54
names: Similarity
messages: Belongs to the peptidase C19 family.

219594:LOC116497232
gene id: 219594:LOC116497232
uniprot id: A0A6J3E3S5
names: Caution
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:TMED5
gene id: 219594:TMED5
uniprot id: A0A6J3D979
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Membrane
messages: cis-Golgi network membrane

219594:ADCK1
gene id: 219594:ADCK1
uniprot id: A0A6J3CZT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. ADCK protein kinase family.
messages: Secreted

219594:DLAT
gene id: 219594:DLAT
uniprot id: A0A6J3E249
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 2 lipoyl cofactors covalently.
messages: Mitochondrion matrix
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

219594:LOC116487962
gene id: 219594:LOC116487962
uniprot id: A0A6J3CS29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cullin family.
messages: Cytoplasm

219594:GPR34
gene id: 219594:GPR34
uniprot id: A0A6J3DMA6
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

219594:MPC2
gene id: 219594:MPC2
uniprot id: A0A6J3D913
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family.
messages: Mediates the uptake of pyruvate into mitochondria.
messages: Membrane
messages: Mitochondrion inner membrane

219594:GLG1
gene id: 219594:GLG1
uniprot id: A0A6J3DNP4
names: Subcellular Location Annotation
messages: Golgi apparatus membrane
messages: Golgi outpost
messages: Membrane
messages: microtubule organizing center

219594:TWISTNB
gene id: 219594:TWISTNB
uniprot id: A0A6J3CQP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic RPA43 RNA polymerase subunit family.
messages: nucleolus

219594:LOC116498864
gene id: 219594:LOC116498864
uniprot id: A0A6J3E6C8
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family. Chitinase class II subfamily.

219594:CASP9
gene id: 219594:CASP9
uniprot id: A0A6J3E1A9
uniprot id: A0A6J3E5J7
names: Similarity
messages: Belongs to the peptidase C14A family.

219594:DRAM2
gene id: 219594:DRAM2
uniprot id: A0A6J3EB07
names: Subcellular Location Annotation
messages: Membrane

219594:SLC30A1
gene id: 219594:SLC30A1
uniprot id: A0A6J3CNL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
messages: Membrane

219594:MED21
gene id: 219594:MED21
uniprot id: A0A6J3EL21
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 21 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

219594:NR2E1
gene id: 219594:NR2E1
uniprot id: A0A6J3CWL2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

219594:B3GALNT2
gene id: 219594:B3GALNT2
uniprot id: A0A6J3CNP7
uniprot id: A0A6J3CQX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

219594:TVP23A
gene id: 219594:TVP23A
uniprot id: A0A6J3DRY5
uniprot id: A0A6J3DTZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP23 family.
messages: Membrane

219594:C1QBP
gene id: 219594:C1QBP
uniprot id: A0A6J3DZB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAM33 family.
messages: Cell membrane

219594:ACADS
gene id: 219594:ACADS
uniprot id: A0A6J3DW88
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

219594:RYR2
gene id: 219594:RYR2
uniprot id: A0A6J3CP36
uniprot id: A0A6J3CP42
uniprot id: A0A6J3CR25
uniprot id: A0A6J3CR31
uniprot id: A0A6J3CRR3
uniprot id: A0A6J3CRR8
uniprot id: A0A6J3CRS3
uniprot id: A0A6J3CU09
uniprot id: A0A6J3CU16
uniprot id: A0A6J3CU23
uniprot id: A0A6J3CV64
uniprot id: A0A6J3CV71
uniprot id: A0A6J3CV76
names: Subcellular Location Annotation
messages: Membrane
messages: Sarcoplasmic reticulum membrane

219594:AP4E1
gene id: 219594:AP4E1
uniprot id: A0A6J3DGK4
uniprot id: A0A6J3DJ71
uniprot id: A0A6J3DKL8
names: Function
names: Similarity
names: Subunit
messages: AP-4 forms a non clathrin-associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system.
messages: Adaptor protein complex 4 (AP-4) is a heterotetramer composed of two large adaptins, a medium adaptin and a small adaptin.
messages: Belongs to the adaptor complexes large subunit family.

219594:CTNNBL1
gene id: 219594:CTNNBL1
uniprot id: A0A6J3DS20
names: Subcellular Location Annotation
messages: Nucleus

219594:MTMR11
gene id: 219594:MTMR11
uniprot id: A0A6J3EE72
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.

219594:NOP56
gene id: 219594:NOP56
uniprot id: A0A6J3CUS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOP5/NOP56 family.
messages: nucleolus

219594:LOC116502183
gene id: 219594:LOC116502183
uniprot id: A0A6J3EPP6
names: Similarity
messages: Belongs to the globin family.

219594:TNS4
gene id: 219594:TNS4
uniprot id: A0A6J3E5J6
names: Similarity
messages: Belongs to the PTEN phosphatase protein family.

219594:MSL3
gene id: 219594:MSL3
uniprot id: A0A6J3CZX6
names: Subcellular Location Annotation
messages: Nucleus

219594:PANX3
gene id: 219594:PANX3
uniprot id: A0A6J3E864
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pannexin family.
messages: Cell membrane
messages: Membrane
messages: Structural component of the gap junctions and the hemichannels.
messages: gap junction

219594:SMDT1
gene id: 219594:SMDT1
uniprot id: A0A6J3EII5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMDT1/EMRE family.
messages: Component of the uniplex complex. Interacts (via the transmembrane region) with MCU (via the first transmembrane region); the interaction is direct.
messages: Essential regulatory subunit of the mitochondrial calcium uniporter complex (uniplex), a complex that mediates calcium uptake into mitochondria.
messages: Membrane
messages: Mitochondrion inner membrane

219594:HESX1
gene id: 219594:HESX1
uniprot id: A0A6J3DJW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ANF homeobox family.
messages: Nucleus

219594:DLGAP5
gene id: 219594:DLGAP5
uniprot id: A0A6J3D1S5
uniprot id: A0A6J3D6R7
names: Similarity
messages: Belongs to the SAPAP family.

219594:NOTCH1
gene id: 219594:NOTCH1
uniprot id: A0A6J3DZP6
uniprot id: A0A6J3E413
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOTCH family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Nucleus

219594:RO60
gene id: 219594:RO60
uniprot id: A0A6J3DDT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ro 60 kDa family.
messages: Cytoplasm

219594:MB21D2
gene id: 219594:MB21D2
uniprot id: A0A6J3DI82
names: Similarity
messages: Belongs to the mab-21 family.

219594:LOC116493979
gene id: 219594:LOC116493979
uniprot id: A0A6J3DLV0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:LBX1
gene id: 219594:LBX1
uniprot id: A0A6J3DBS2
names: Subcellular Location Annotation
messages: Nucleus

219594:ORAI1
gene id: 219594:ORAI1
uniprot id: A0A6J3DV84
uniprot id: A0A6J3DZD4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Orai family.
messages: Membrane

219594:G6PC2
gene id: 219594:G6PC2
uniprot id: A0A6J3D570
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glucose-6-phosphatase family.
messages: Endoplasmic reticulum membrane

219594:HTR1A
gene id: 219594:HTR1A
uniprot id: A0A6J3ELY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:VGLL1
gene id: 219594:VGLL1
uniprot id: A0A6J3DQS8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vestigial family.
messages: May act as a specific coactivator for the mammalian TEFs.
messages: Nucleus

219594:PPP1R3B
gene id: 219594:PPP1R3B
uniprot id: A0A6J3D0J7
names: Subunit
messages: Interacts with glycogen, PPP1CC catalytic subunit of PP1 and PYGL. Associates with glycogen particles. Forms complexes with debranching enzyme, glycogen phosphorylase, glycogen synthase and phosphorylase kinase which is necessary for its regulation of PP1 activity.

219594:C3H6orf120
gene id: 219594:C3H6orf120
uniprot id: A0A6J3CKI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0669 family.
messages: Secreted

219594:BMP1
gene id: 219594:BMP1
uniprot id: A0A6J3E8Q8
names: Caution
names: Cofactor
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:ATP13A3
gene id: 219594:ATP13A3
uniprot id: A0A6J3DFR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily.
messages: Membrane

219594:RHBDF1
gene id: 219594:RHBDF1
uniprot id: A0A6J3DV83
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S54 family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Regulates ADAM17 protease, a sheddase of the epidermal growth factor (EGF) receptor ligands and TNF, thereby plays a role in sleep, cell survival, proliferation, migration and inflammation. Does not exhibit any protease activity on its own.

219594:LRP1B
gene id: 219594:LRP1B
uniprot id: A0A6J3D8W8
names: Caution
names: Similarity
messages: Belongs to the LDLR family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:LOC116494072
gene id: 219594:LOC116494072
uniprot id: A0A6J3DJM4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:POLR2L
gene id: 219594:POLR2L
uniprot id: A0A6J3D4X6
names: Similarity
messages: Belongs to the archaeal Rpo10/eukaryotic RPB10 RNA polymerase subunit family.

219594:LOC116491442
gene id: 219594:LOC116491442
uniprot id: A0A6J3DAM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta-microseminoprotein family.
messages: Secreted

219594:LOC116485682
gene id: 219594:LOC116485682
uniprot id: A0A6J3CG71
names: Similarity
names: Subunit
messages: Belongs to the avian keratin family.
messages: The avian keratins (F-ker, S-ker, C-ker and B-ker) are a complex mixture of very similar polypeptides.

219594:ABCD3
gene id: 219594:ABCD3
uniprot id: A0A6J3D907
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCD family. Peroxisomal fatty acyl CoA transporter (TC 3.A.1.203) subfamily.
messages: Membrane
messages: Peroxisome membrane

219594:LOC116500797
gene id: 219594:LOC116500797
uniprot id: A0A6J3EDZ4
uniprot id: A0A6J3EKQ6
names: Similarity
messages: Belongs to the cystatin family.

219594:ERRFI1
gene id: 219594:ERRFI1
uniprot id: A0A6J3E6M2
names: Subcellular Location Annotation
messages: Membrane
messages: Nucleus

219594:SPATA18
gene id: 219594:SPATA18
uniprot id: A0A6J3CWB0
uniprot id: A0A6J3D138
uniprot id: A0A6J3D291
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIEAP family.
messages: Cytoplasm
messages: Membrane
messages: Mitochondrion outer membrane

219594:REXO4
gene id: 219594:REXO4
uniprot id: A0A6J3E246
names: Similarity
messages: Belongs to the REXO4 family.

219594:TLCD2
gene id: 219594:TLCD2
uniprot id: A0A6J3DZI0
names: Subcellular Location Annotation
messages: Membrane

219594:TIMM8A
gene id: 219594:TIMM8A
uniprot id: A0A6J3DQV5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the small Tim family.
messages: Heterohexamer.
messages: Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.
messages: Mitochondrion inner membrane
messages: The twin CX3C motif contains 4 conserved Cys residues that form 2 disulfide bonds in the mitochondrial intermembrane space.

219594:MGAT2
gene id: 219594:MGAT2
uniprot id: A0A6J3D4Q7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 16 (GT16) protein family.
messages: Golgi apparatus membrane
messages: Membrane

219594:LYPD6
gene id: 219594:LYPD6
uniprot id: A0A6J3D9Z4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

219594:MMP11
gene id: 219594:MMP11
uniprot id: A0A6J3E0C0
names: Similarity
messages: Belongs to the peptidase M10A family.

219594:JAG1
gene id: 219594:JAG1
uniprot id: A0A6J3CQY0
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Putative Notch ligand involved in the mediation of Notch signaling.

219594:LOC116493955
gene id: 219594:LOC116493955
uniprot id: A0A6J3DQD4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

219594:LOC116495278
gene id: 219594:LOC116495278
uniprot id: A0A6J3DSB9
names: Similarity
messages: Belongs to the cytochrome P450 family.

219594:CLCN2
gene id: 219594:CLCN2
uniprot id: A0A6J3DDP3
uniprot id: A0A6J3DHN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel (TC 2.A.49) family. ClC-2/CLCN2 subfamily.
messages: Cell membrane
messages: Membrane

219594:OSBPL6
gene id: 219594:OSBPL6
uniprot id: A0A6J3D383
uniprot id: A0A6J3D5R6
uniprot id: A0A6J3D648
uniprot id: A0A6J3D8B3
uniprot id: A0A6J3D924
names: Similarity
messages: Belongs to the OSBP family.

219594:KHDRBS3
gene id: 219594:KHDRBS3
uniprot id: A0A6J3CF95
uniprot id: A0A6J3CJT8
uniprot id: A0A6J3CLI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KHDRBS family.
messages: Cytoplasm

219594:PACSIN1
gene id: 219594:PACSIN1
uniprot id: A0A6J3EBH0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Cytoplasmic vesicle membrane
messages: Membrane
messages: cytosol
messages: ruffle membrane
messages: synaptosome

219594:SERINC5
gene id: 219594:SERINC5
uniprot id: A0A6J3EGS4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TDE1 family.
messages: Cell membrane
messages: Membrane

219594:SLC26A5
gene id: 219594:SLC26A5
uniprot id: A0A6J3EHI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

219594:TMEM70
gene id: 219594:TMEM70
uniprot id: A0A6J3CJU8
names: Similarity
messages: Belongs to the TMEM70 family.

219594:ETS1
gene id: 219594:ETS1
uniprot id: A0A6J3E2D7
uniprot id: A0A6J3E7D0
uniprot id: A0A6J3E8P8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Cytoplasm
messages: Nucleus

219594:ERLEC1
gene id: 219594:ERLEC1
uniprot id: A0A6J3CST6
names: Subcellular Location Annotation
messages: Endoplasmic reticulum lumen

219594:CLPTM1L
gene id: 219594:CLPTM1L
uniprot id: A0A6J3CHY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CLPTM1 family.
messages: Membrane

219594:LOC116500319
gene id: 219594:LOC116500319
uniprot id: A0A6J3ED34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:HRH2
gene id: 219594:HRH2
uniprot id: A0A6J3DTC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:PRKACB
gene id: 219594:PRKACB
uniprot id: A0A6J3DBM0
uniprot id: A0A6J3DEK1
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. cAMP subfamily.

219594:ESRP1
gene id: 219594:ESRP1
uniprot id: A0A6J3CH28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ESRP family.
messages: Nucleus

219594:EIF4G3
gene id: 219594:EIF4G3
uniprot id: A0A6J3E1J6
uniprot id: A0A6J3E2W6
uniprot id: A0A6J3E2X0
uniprot id: A0A6J3E5T9
uniprot id: A0A6J3E5U4
uniprot id: A0A6J3E6K4
uniprot id: A0A6J3E6K9
uniprot id: A0A6J3E7S3
uniprot id: A0A6J3E7S8
uniprot id: A0A6J3E7T5
names: Similarity
messages: Belongs to the eukaryotic initiation factor 4G family.

219594:EPC2
gene id: 219594:EPC2
uniprot id: A0A6J3D4T6
uniprot id: A0A6J3DAR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enhancer of polycomb family.
messages: Nucleus

219594:MED10
gene id: 219594:MED10
uniprot id: A0A6J3CF31
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 10 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

219594:MYT1
gene id: 219594:MYT1
uniprot id: A0A6J3DUE9
uniprot id: A0A6J3DYG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MYT1 family.
messages: Nucleus

219594:RYBP
gene id: 219594:RYBP
uniprot id: A0A6J3DHL8
names: Subcellular Location Annotation
messages: Nucleus

219594:XPO1
gene id: 219594:XPO1
uniprot id: A0A6J3CN38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exportin family.
messages: Cytoplasm

219594:OPRL1
gene id: 219594:OPRL1
uniprot id: A0A6J3DWN2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: G-protein coupled opioid receptor that functions as receptor for the endogenous neuropeptide nociceptin. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling via G proteins mediates inhibition of adenylate cyclase activity and calcium channel activity. Arrestins modulate signaling via G proteins and mediate the activation of alternative signaling pathways that lead to the activation of MAP kinases. Plays a role in modulating nociception and the perception of pain. Plays a role in the regulation of locomotor activity by the neuropeptide nociceptin.
messages: Membrane
messages: Vesicle

219594:PURA
gene id: 219594:PURA
uniprot id: A0A6J3DU80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PUR DNA-binding protein family.
messages: Nucleus

219594:RNF168
gene id: 219594:RNF168
uniprot id: A0A6J3DFM3
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNF168 family.
messages: E3 ubiquitin-protein ligase required for accumulation of repair proteins to sites of DNA damage. Acts with UBE2N/UBC13 to amplify the RNF8-dependent histone ubiquitination. Recruited to sites of DNA damage at double-strand breaks (DSBs) by binding to ubiquitinated histone H2A and ubiquitinates histone H2A and H2AX, leading to amplify the RNF8-dependent H2A ubiquitination and promoting the formation of 'Lys-63'-linked ubiquitin conjugates. This leads to concentrate ubiquitinated histones H2A and H2AX at DNA lesions to the threshold required for recruitment of TP53BP1 and BRCA1. Catalyzes monoubiquitination of 'Lys-13' and 'Lys-15' of nucleosomal histone H2A (H2AK13Ub and H2AK15Ub, respectively).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Nucleus
messages: The MIU motif (motif interacting with ubiquitin) mediates the interaction with both 'Lys-48'- and 'Lys-63'-linked ubiquitin chains. The UMI motif mediates interaction with ubiquitin with a preference for 'Lys-63'-linked ubiquitin. The specificity for different types of ubiquitin is mediated by juxtaposition of ubiquitin-binding motifs (MIU and UMI motifs) with LR motifs (LRMs).

219594:VPS54
gene id: 219594:VPS54
uniprot id: A0A6J3CR13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS54 family.
messages: trans-Golgi network

219594:PRDM4
gene id: 219594:PRDM4
uniprot id: A0A6J3D8P9
names: Function
names: Subcellular Location Annotation
messages: May function as a transcription factor involved in cell differentiation.
messages: Nucleus

219594:AP4S1
gene id: 219594:AP4S1
uniprot id: A0A6J3D3R9
names: Similarity
messages: Belongs to the adaptor complexes small subunit family.

219594:AQR
gene id: 219594:AQR
uniprot id: A0A6J3D369
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CWF11 family.
messages: Nucleus

219594:DAG1
gene id: 219594:DAG1
uniprot id: A0A6J3DEA4
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane
messages: The dystroglycan complex is involved in a number of processes including laminin and basement membrane assembly, sarcolemmal stability, cell survival, peripheral nerve myelination, nodal structure, cell migration, and epithelial polarization.
messages: Transmembrane protein that plays important roles in connecting the extracellular matrix to the cytoskeleton. Acts as a cell adhesion receptor in both muscle and non-muscle tissues. Receptor for both DMD and UTRN and, through these interactions, scaffolds axin to the cytoskeleton. Also functions in cell adhesion-mediated signaling and implicated in cell polarity.
messages: extracellular space
messages: nucleoplasm
messages: sarcolemma

219594:RPRM
gene id: 219594:RPRM
uniprot id: A0A6J3D7D0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the reprimo family.
messages: Cytoplasm
messages: Membrane

219594:ACTC1
gene id: 219594:ACTC1
uniprot id: A0A6J3D4K3
names: Similarity
messages: Belongs to the actin family.

219594:AQP5
gene id: 219594:AQP5
uniprot id: A0A6J3EFC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

219594:PPP2R5D
gene id: 219594:PPP2R5D
uniprot id: A0A6J3CT89
names: Similarity
messages: Belongs to the phosphatase 2A regulatory subunit B56 family.

219594:WEE1
gene id: 219594:WEE1
uniprot id: A0A6J3D487
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. WEE1 subfamily.
messages: Binds 2 magnesium ions per subunit.
messages: Nucleus

219594:CDH7
gene id: 219594:CDH7
uniprot id: A0A6J3CF22
uniprot id: A0A6J3CGP7
uniprot id: A0A6J3CJL1
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane
messages: Membrane

219594:CEP57
gene id: 219594:CEP57
uniprot id: A0A6J3EN87
names: Similarity
messages: Belongs to the translokin family.

219594:MTMR8
gene id: 219594:MTMR8
uniprot id: A0A6J3DRU7
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.

219594:SUPV3L1
gene id: 219594:SUPV3L1
uniprot id: A0A6J3D7W8
uniprot id: A0A6J3DBB4
uniprot id: A0A6J3DDH9
uniprot id: A0A6J3DDV3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the helicase family.
messages: mitochondrion nucleoid

219594:C1H11orf54
gene id: 219594:C1H11orf54
uniprot id: A0A6J3DID3
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Exhibits ester hydrolase activity on the substrate p-nitrophenyl acetate.
messages: Monomer.
messages: Nucleus

219594:TMEM144
gene id: 219594:TMEM144
uniprot id: A0A6J3CUW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM144 family.
messages: Membrane

219594:CDC42
gene id: 219594:CDC42
uniprot id: A0A6J3E219
uniprot id: A0A6J3E4W1
uniprot id: A0A6J3E6R4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rho family. CDC42 subfamily.
messages: Cell membrane
messages: Membrane
messages: Midbody
messages: Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state.

219594:TTC19
gene id: 219594:TTC19
uniprot id: A0A6J3E0Q0
uniprot id: A0A6J3E570
names: Similarity
messages: Belongs to the TTC19 family.

219594:LOC116501373
gene id: 219594:LOC116501373
uniprot id: A0A6J3EGB7
uniprot id: A0A6J3EHU1
uniprot id: A0A6J3ELK6
uniprot id: A0A6J3ELN2
uniprot id: A0A6J3EN10
names: Similarity
messages: Belongs to the PIAS family.

219594:ATP13A2
gene id: 219594:ATP13A2
uniprot id: A0A6J3E812
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily.
messages: Membrane

219594:SSX2IP
gene id: 219594:SSX2IP
uniprot id: A0A6J3DDT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIP family.
messages: adherens junction
messages: centriolar satellite

219594:SEC16A
gene id: 219594:SEC16A
uniprot id: A0A6J3DX97
uniprot id: A0A6J3DZ17
uniprot id: A0A6J3E1F3
uniprot id: A0A6J3E297
uniprot id: A0A6J3E3D5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SEC16 family.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Membrane
messages: Plays a role in the organization of the endoplasmic reticulum exit sites (ERES), also known as transitional endoplasmic reticulum (tER). Required for secretory cargo traffic from the endoplasmic reticulum to the Golgi apparatus.
messages: SEC16A and SEC16B are each present in multiple copies in a heteromeric complex.

219594:VPS4B
gene id: 219594:VPS4B
uniprot id: A0A6J3CHD3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family.
messages: Endosome membrane
messages: Late endosome membrane
messages: Membrane

219594:GNPDA1
gene id: 219594:GNPDA1
uniprot id: A0A6J3DU42
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family.
messages: Cytoplasm
messages: Homohexamer.

219594:LOC116499743
gene id: 219594:LOC116499743
uniprot id: A0A6J3EB95
names: Similarity
names: Subunit
messages: Belongs to the avian keratin family.
messages: The avian keratins (F-ker, S-ker, C-ker and B-ker) are a complex mixture of very similar polypeptides.

219594:CAB39L
gene id: 219594:CAB39L
uniprot id: A0A6J3DE90
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mo25 family.
messages: Component of a complex that binds and activates STK11/LKB1. In the complex, required to stabilize the interaction between CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta) and STK11/LKB1.
messages: Component of a trimeric complex composed of STK11/LKB1, STRAD (STRADA or STRADB) and CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta): the complex tethers STK11/LKB1 in the cytoplasm and stimulates its catalytic activity.

219594:LOC116497222
gene id: 219594:LOC116497222
uniprot id: A0A6J3DZF5
uniprot id: A0A6J3E3P5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Spinster (TC 2.A.1.49) family.
messages: Membrane

219594:MKI67
gene id: 219594:MKI67
uniprot id: A0A6J3D9N5
uniprot id: A0A6J3DCH5
names: Subcellular Location Annotation
messages: Nucleus

219594:MRPL54
gene id: 219594:MRPL54
uniprot id: A0A6J3EE89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL54 family.
messages: Mitochondrion

219594:ALG8
gene id: 219594:ALG8
uniprot id: A0A6J3CZV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ALG6/ALG8 glucosyltransferase family.
messages: Endoplasmic reticulum membrane
messages: Membrane

219594:CFAP300
gene id: 219594:CFAP300
uniprot id: A0A6J3EI43
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CFAP300 family.
messages: Cilium- and flagellum-specific protein that plays a role in axonemal structure organization and motility. May play a role in outer and inner dynein arm assembly.
messages: Cytoplasm

219594:INSIG2
gene id: 219594:INSIG2
uniprot id: A0A6J3D6S2
uniprot id: A0A6J3D9H9
uniprot id: A0A6J3DA25
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the INSIG family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mediates feedback control of cholesterol synthesis.
messages: Membrane

219594:UTP25
gene id: 219594:UTP25
uniprot id: A0A6J3CS13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UTP25 family.
messages: nucleolus

219594:LOC116486300
gene id: 219594:LOC116486300
uniprot id: A0A6J3CJT1
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

219594:GRM2
gene id: 219594:GRM2
uniprot id: A0A6J3DKY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 3 family.
messages: Cell membrane
messages: Membrane

219594:DPYD
gene id: 219594:DPYD
uniprot id: A0A6J3DF73
uniprot id: A0A6J3DFB1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the dihydropyrimidine dehydrogenase family.
messages: Binds 4 [4Fe-4S] clusters. Contains approximately 16 iron atoms per subunit.
messages: Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine.

219594:ARL6IP5
gene id: 219594:ARL6IP5
uniprot id: A0A6J3DGQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA1 family.
messages: Membrane

219594:GLRA3
gene id: 219594:GLRA3
uniprot id: A0A6J3CWC2
uniprot id: A0A6J3CWR0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synapse
messages: Synaptic cell membrane

219594:LOC116499485
gene id: 219594:LOC116499485
uniprot id: A0A6J3EDZ5
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.

219594:SLC13A3
gene id: 219594:SLC13A3
uniprot id: A0A6J3DU94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. NADC subfamily.
messages: Membrane

219594:BCL7B
gene id: 219594:BCL7B
uniprot id: A0A6J3E159
uniprot id: A0A6J3E3W8
names: Similarity
messages: Belongs to the BCL7 family.

219594:HABP2
gene id: 219594:HABP2
uniprot id: A0A6J3D9H0
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

219594:SEC63
gene id: 219594:SEC63
uniprot id: A0A6J3CSK5
names: Subcellular Location Annotation
messages: Membrane

219594:DARS2
gene id: 219594:DARS2
uniprot id: A0A6J3DGL8
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.

219594:NPR3
gene id: 219594:NPR3
uniprot id: A0A6J3EDN7
uniprot id: A0A6J3EJ10
names: Subcellular Location Annotation
messages: Membrane

219594:SNAP47
gene id: 219594:SNAP47
uniprot id: A0A6J3CL97
names: Similarity
messages: Belongs to the SVAP1 family.

219594:PI4KB
gene id: 219594:PI4KB
uniprot id: A0A6J3EBD3
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.

219594:LOC116501292
gene id: 219594:LOC116501292
uniprot id: A0A6J3EG42
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:PTPN3
gene id: 219594:PTPN3
uniprot id: A0A6J3CKD5
uniprot id: A0A6J3CMC4
uniprot id: A0A6J3CNT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class subfamily.
messages: cytoskeleton

219594:HIKESHI
gene id: 219594:HIKESHI
uniprot id: A0A6J3DF55
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a specific nuclear import carrier for HSP70 proteins following heat-shock stress: acts by mediating the nucleoporin-dependent translocation of ATP-bound HSP70 proteins into the nucleus. HSP70 proteins import is required to protect cells from heat shock damages. Does not translocate ADP-bound HSP70 proteins into the nucleus.
messages: Belongs to the OPI10 family.
messages: Cytoplasm
messages: Forms an asymmetric homodimer; required for binding and nuclear import of HSP70 proteins. Interacts with ATP-bound HSP70 proteins.
messages: Nucleus
messages: cytosol

219594:OCA2
gene id: 219594:OCA2
uniprot id: A0A6J3EEV3
names: Subcellular Location Annotation
messages: Membrane

219594:LOC116495085
gene id: 219594:LOC116495085
uniprot id: A0A6J3DV18
names: Subcellular Location Annotation
names: Subunit
messages: Cell membrane
messages: Interacts with NCDN.
messages: Membrane

219594:HAPLN1
gene id: 219594:HAPLN1
uniprot id: A0A6J3EHW6
uniprot id: A0A6J3EJI7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:LOC116494776
gene id: 219594:LOC116494776
uniprot id: A0A6J3DS12
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thymosin beta family.
messages: Plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization.
messages: cytoskeleton

219594:LOC116490152
gene id: 219594:LOC116490152
uniprot id: A0A6J3D3S0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

219594:MEX3C
gene id: 219594:MEX3C
uniprot id: A0A6J3ECH5
names: Subcellular Location Annotation
messages: Cytoplasm

219594:WARS1
gene id: 219594:WARS1
uniprot id: A0A6J3CX34
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

219594:VSX1
gene id: 219594:VSX1
uniprot id: A0A6J3CKE6
names: Subcellular Location Annotation
messages: Nucleus

219594:ACOT13
gene id: 219594:ACOT13
uniprot id: A0A6J3CDD0
names: Similarity
messages: Belongs to the thioesterase PaaI family.

219594:LOC116498609
gene id: 219594:LOC116498609
uniprot id: A0A6J3E5C3
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

219594:HTR7
gene id: 219594:HTR7
uniprot id: A0A6J3D822
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:LOC116501284
gene id: 219594:LOC116501284
uniprot id: A0A6J3EMS2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:RELN
gene id: 219594:RELN
uniprot id: A0A6J3DA22
uniprot id: A0A6J3DDQ8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the reelin family.
messages: Extracellular matrix serine protease that plays a role in layering of neurons in the cerebral cortex and cerebellum. Regulates microtubule function in neurons and neuronal migration. Affects migration of sympathetic preganglionic neurons in the spinal cord, where it seems to act as a barrier to neuronal migration. Enzymatic activity is important for the modulation of cell adhesion. Binding to the extracellular domains of lipoprotein receptors VLDLR and LRP8/APOER2 induces tyrosine phosphorylation of DAB1 and modulation of TAU phosphorylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Oligomer of disulfide-linked homodimers. Binds to the ectodomains of VLDLR and LRP8/APOER2.
messages: extracellular matrix

219594:KCNE5
gene id: 219594:KCNE5
uniprot id: A0A6J3DRN1
names: Similarity
messages: Belongs to the potassium channel KCNE family.

219594:SURF4
gene id: 219594:SURF4
uniprot id: A0A6J3DZ87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SURF4 family.
messages: Membrane

219594:LOC116495307
gene id: 219594:LOC116495307
uniprot id: A0A6J3DUJ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
messages: Endoplasmic reticulum membrane
messages: Microsome membrane

219594:LCORL
gene id: 219594:LCORL
uniprot id: A0A6J3CYJ0
names: Subcellular Location Annotation
messages: Nucleus

219594:DAO
gene id: 219594:DAO
uniprot id: A0A6J3DT96
uniprot id: A0A6J3DY83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DAMOX/DASOX family.
messages: Peroxisome

219594:THNSL1
gene id: 219594:THNSL1
uniprot id: A0A6J3CN00
names: Similarity
messages: Belongs to the threonine synthase family.

219594:CRK
gene id: 219594:CRK
uniprot id: A0A6J3E598
names: Similarity
messages: Belongs to the CRK family.

219594:LOC116495651
gene id: 219594:LOC116495651
uniprot id: A0A6J3DRW5
names: Similarity
messages: Belongs to the FAM83 family.

219594:RARRES1
gene id: 219594:RARRES1
uniprot id: A0A6J3DIV0
names: Similarity
messages: Belongs to the protease inhibitor I47 (latexin) family.

219594:GDPD1
gene id: 219594:GDPD1
uniprot id: A0A6J3E5N1
names: Similarity
messages: Belongs to the glycerophosphoryl diester phosphodiesterase family.

219594:TMEM200C
gene id: 219594:TMEM200C
uniprot id: A0A6J3CER6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM200 family.
messages: Membrane

219594:AKR1D1
gene id: 219594:AKR1D1
uniprot id: A0A6J3DM20
names: Similarity
messages: Belongs to the aldo/keto reductase family.

219594:RAB38
gene id: 219594:RAB38
uniprot id: A0A6J3ENH8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Membrane
messages: The small GTPases Rab are key regulators in vesicle trafficking.

219594:NPTX2
gene id: 219594:NPTX2
uniprot id: A0A6J3DQ45
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:ARHGDIB
gene id: 219594:ARHGDIB
uniprot id: A0A6J3EG41
names: Similarity
messages: Belongs to the Rho GDI family.

219594:HDLBP
gene id: 219594:HDLBP
uniprot id: A0A6J3DC71
names: Subcellular Location Annotation
messages: Cytoplasm

219594:TWF1
gene id: 219594:TWF1
uniprot id: A0A6J3EP56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the actin-binding proteins ADF family. Twinfilin subfamily.
messages: cytoskeleton

219594:LBH
gene id: 219594:LBH
uniprot id: A0A6J3CSR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LBH family.
messages: Cytoplasm
messages: Nucleus

219594:TERF2
gene id: 219594:TERF2
uniprot id: A0A6J3DJW3
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Binds the telomeric double-stranded 5'-TTAGGG-3' repeat.
messages: Homodimer.
messages: Nucleus

219594:COPS3
gene id: 219594:COPS3
uniprot id: A0A6J3DRW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSN3 family.
messages: Cytoplasm
messages: Nucleus

219594:LOC116498352
gene id: 219594:LOC116498352
uniprot id: A0A6J3E4C0
names: Similarity
names: Subunit
messages: Belongs to the avian keratin family.
messages: The avian keratins (F-ker, S-ker, C-ker and B-ker) are a complex mixture of very similar polypeptides.

219594:IMPACT
gene id: 219594:IMPACT
uniprot id: A0A6J3CIV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IMPACT family.
messages: Cytoplasm

219594:CCDC172
gene id: 219594:CCDC172
uniprot id: A0A6J3D9H5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCDC172 family.
messages: Cytoplasm

219594:PSPC1
gene id: 219594:PSPC1
uniprot id: A0A6J3D2Y8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PSPC family.
messages: Cytoplasm
messages: Nucleus matrix
messages: Nucleus speckle
messages: nucleolus

219594:ADGRG7
gene id: 219594:ADGRG7
uniprot id: A0A6J3DIW5
names: Subcellular Location Annotation
messages: Membrane

219594:DDX41
gene id: 219594:DDX41
uniprot id: A0A6J3DUR9
names: Similarity
messages: Belongs to the DEAD box helicase family. DDX41 subfamily.

219594:NQO1
gene id: 219594:NQO1
uniprot id: A0A6J3DJV3
names: Similarity
messages: Belongs to the NAD(P)H dehydrogenase (quinone) family.

219594:PUS10
gene id: 219594:PUS10
uniprot id: A0A6J3CKL6
names: Similarity
messages: Belongs to the pseudouridine synthase Pus10 family.

219594:NDUFB1
gene id: 219594:NDUFB1
uniprot id: A0A6J3D1T4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFB1 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

219594:RICTOR
gene id: 219594:RICTOR
uniprot id: A0A6J3EDF7
uniprot id: A0A6J3EH55
uniprot id: A0A6J3EIR7
names: Similarity
messages: Belongs to the RICTOR family.

219594:LOC116500309
gene id: 219594:LOC116500309
uniprot id: A0A6J3ED24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:LOC116502121
gene id: 219594:LOC116502121
uniprot id: A0A6J3EPE0
names: Similarity
messages: Belongs to the cystatin family.

219594:LOC116498320
gene id: 219594:LOC116498320
uniprot id: A0A6J3E979
names: Similarity
names: Subunit
messages: Belongs to the avian keratin family.
messages: The avian keratins (F-ker, S-ker, C-ker and B-ker) are a complex mixture of very similar polypeptides.

219594:DIS3L
gene id: 219594:DIS3L
uniprot id: A0A6J3DMZ8
uniprot id: A0A6J3DNM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNR ribonuclease family.
messages: Cytoplasm

219594:SPOUT1
gene id: 219594:SPOUT1
uniprot id: A0A6J3DXN9
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily.

219594:PGF
gene id: 219594:PGF
uniprot id: A0A6J3D4S8
names: Similarity
messages: Belongs to the PDGF/VEGF growth factor family.

219594:DYRK3
gene id: 219594:DYRK3
uniprot id: A0A6J3EAW3
uniprot id: A0A6J3ECF6
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MNB/DYRK subfamily.

219594:AQP2
gene id: 219594:AQP2
uniprot id: A0A6J3EFD3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

219594:AKAP1
gene id: 219594:AKAP1
uniprot id: A0A6J3E106
names: Subcellular Location Annotation
messages: Cytoplasm

219594:RAB3GAP2
gene id: 219594:RAB3GAP2
uniprot id: A0A6J3CND5
uniprot id: A0A6J3CPC2
uniprot id: A0A6J3CRL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Rab3-GAP regulatory subunit family.
messages: Cytoplasm

219594:TUB
gene id: 219594:TUB
uniprot id: A0A6J3CX04
uniprot id: A0A6J3CZ94
uniprot id: A0A6J3CZK2
uniprot id: A0A6J3D1U6
uniprot id: A0A6J3D2Y6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TUB family.
messages: Secreted

219594:CNTNAP2
gene id: 219594:CNTNAP2
uniprot id: A0A6J3CKQ5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neurexin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: paranodal septate junction

219594:LOC116500237
gene id: 219594:LOC116500237
uniprot id: A0A6J3EI45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. BTN/MOG family.
messages: Membrane

219594:ADCY5
gene id: 219594:ADCY5
uniprot id: A0A6J3D5G3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Binds 2 magnesium ions per subunit. Is also active with manganese (in vitro).
messages: Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.
messages: Membrane

219594:TRIM32
gene id: 219594:TRIM32
uniprot id: A0A6J3DXN4
uniprot id: A0A6J3E1U7
names: Similarity
messages: Belongs to the TRIM/RBCC family.

219594:LOC116498866
gene id: 219594:LOC116498866
uniprot id: A0A6J3EBF4
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family. Chitinase class II subfamily.

219594:COG1
gene id: 219594:COG1
uniprot id: A0A6J3DVQ6
uniprot id: A0A6J3DZW2
names: Similarity
messages: Belongs to the COG1 family.

219594:NR3C2
gene id: 219594:NR3C2
uniprot id: A0A6J3CUE9
uniprot id: A0A6J3CYA9
names: Subcellular Location Annotation
messages: Nucleus

219594:EIF4E2
gene id: 219594:EIF4E2
uniprot id: A0A6J3DD50
uniprot id: A0A6J3DH22
names: Similarity
messages: Belongs to the eukaryotic initiation factor 4E family.

219594:RPL31
gene id: 219594:RPL31
uniprot id: A0A6J3EJC9
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL31 family.
messages: Component of the large ribosomal subunit.

219594:LACC1
gene id: 219594:LACC1
uniprot id: A0A6J3E7G8
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

219594:TNC
gene id: 219594:TNC
uniprot id: A0A6J3DXH6
uniprot id: A0A6J3E2H6
uniprot id: A0A6J3E3K5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tenascin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

219594:PPP1R2
gene id: 219594:PPP1R2
uniprot id: A0A6J3DCZ0
uniprot id: A0A6J3DII0
uniprot id: A0A6J3DJ34
names: Similarity
messages: Belongs to the protein phosphatase inhibitor 2 family.

219594:FAM241A
gene id: 219594:FAM241A
uniprot id: A0A6J3CWD1
uniprot id: A0A6J3CYK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM241 family.
messages: Membrane

219594:HOPX
gene id: 219594:HOPX
uniprot id: A0A6J3CU27
uniprot id: A0A6J3CWC6
names: Subcellular Location Annotation
messages: Nucleus

219594:NTN3
gene id: 219594:NTN3
uniprot id: A0A6J3DQC4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:SERINC3
gene id: 219594:SERINC3
uniprot id: A0A6J3DTN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TDE1 family.
messages: Membrane

219594:MALL
gene id: 219594:MALL
uniprot id: A0A6J3CSD6
names: Subcellular Location Annotation
messages: Membrane

219594:LOC116499656
gene id: 219594:LOC116499656
uniprot id: A0A6J3E9H2
names: Similarity
names: Subunit
messages: Belongs to the avian keratin family.
messages: The avian keratins (F-ker, S-ker, C-ker and B-ker) are a complex mixture of very similar polypeptides.

219594:DMRTA2
gene id: 219594:DMRTA2
uniprot id: A0A6J3DEL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DMRT family.
messages: Nucleus

219594:TECPR1
gene id: 219594:TECPR1
uniprot id: A0A6J3DVV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TECPR1 family.
messages: Lysosome membrane
messages: autophagosome membrane

219594:ITGB2
gene id: 219594:ITGB2
uniprot id: A0A6J3D7D6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin beta chain family.
messages: Membrane

219594:LOC116493851
gene id: 219594:LOC116493851
uniprot id: A0A6J3DIR5
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Membrane

219594:VGLL4
gene id: 219594:VGLL4
uniprot id: A0A6J3DE92
uniprot id: A0A6J3DH04
uniprot id: A0A6J3DKD8
names: Function
names: Similarity
messages: Belongs to the vestigial family.
messages: May act as a specific coactivator for the mammalian TEFs.

219594:VPS29
gene id: 219594:VPS29
uniprot id: A0A6J3DU46
uniprot id: A0A6J3DYZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway.
messages: Belongs to the VPS29 family.
messages: Endosome membrane

219594:LIAS
gene id: 219594:LIAS
uniprot id: A0A6J3CSJ4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Mitochondrion

219594:SSRP1
gene id: 219594:SSRP1
uniprot id: A0A6J3D390
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SSRP1 family.
messages: Chromosome
messages: Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of the nucleosome following the passage of RNA polymerase II.
messages: Nucleus

219594:LOC116486476
gene id: 219594:LOC116486476
uniprot id: A0A6J3CI23
uniprot id: A0A6J3CJI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Endoplasmic reticulum membrane

219594:FN3K
gene id: 219594:FN3K
uniprot id: A0A6J3DWI8
names: Similarity
messages: Belongs to the fructosamine kinase family.

219594:UGGT2
gene id: 219594:UGGT2
uniprot id: A0A6J3EBW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 8 family.
messages: Endoplasmic reticulum lumen

219594:CCT4
gene id: 219594:CCT4
uniprot id: A0A6J3CS80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCP-1 chaperonin family.
messages: Cytoplasm

219594:ETF1
gene id: 219594:ETF1
uniprot id: A0A6J3DSD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic release factor 1 family.
messages: Cytoplasm

219594:UTP3
gene id: 219594:UTP3
uniprot id: A0A6J3CTN7
names: Similarity
messages: Belongs to the SAS10 family.

219594:CLDN11
gene id: 219594:CLDN11
uniprot id: A0A6J3DJ39
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

219594:IL18
gene id: 219594:IL18
uniprot id: A0A6J3E266
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-1 family.
messages: Cytoplasm
messages: Secreted

219594:CLUL1
gene id: 219594:CLUL1
uniprot id: A0A6J3CHW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the clusterin family.
messages: Secreted

219594:KCNV1
gene id: 219594:KCNV1
uniprot id: A0A6J3CMZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the potassium channel family. V (TC 1.A.1.2) subfamily. Kv8.1/KCNV1 sub-subfamily.
messages: Heteromultimer with KCNB1 and KCNB2. Interacts with KCNC4 and KCND1.
messages: Membrane
messages: Potassium channel subunit that does not form functional channels by itself. Modulates KCNB1 and KCNB2 channel activity by shifting the threshold for inactivation to more negative values and by slowing the rate of inactivation. Can down-regulate the channel activity of KCNB1, KCNB2, KCNC4 and KCND1, possibly by trapping them in intracellular membranes.

219594:GALR3
gene id: 219594:GALR3
uniprot id: A0A6J3ERF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

219594:ENPP3
gene id: 219594:ENPP3
uniprot id: A0A6J3CSW5
names: Subcellular Location Annotation
messages: Secreted

219594:LOC116500390
gene id: 219594:LOC116500390
uniprot id: A0A6J3EH23
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alpha/beta interferon family.
messages: Has antiviral activities.
messages: Secreted

219594:MYO5B
gene id: 219594:MYO5B
uniprot id: A0A6J3EK91
uniprot id: A0A6J3ELS6
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

219594:USP33
gene id: 219594:USP33
uniprot id: A0A6J3D9E0
uniprot id: A0A6J3DC28
uniprot id: A0A6J3DD15
uniprot id: A0A6J3DF47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C19 family. USP20/USP33 subfamily.
messages: centrosome
messages: perinuclear region

219594:LOC116486720
gene id: 219594:LOC116486720
uniprot id: A0A6J3CLX4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

219594:FRG1
gene id: 219594:FRG1
uniprot id: A0A6J3CXQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FRG1 family.
messages: Cajal body
messages: nucleolus

219594:PAH
gene id: 219594:PAH
uniprot id: A0A6J3E5E8
names: Similarity
messages: Belongs to the biopterin-dependent aromatic amino acid hydroxylase family.

219594:NLGN3
gene id: 219594:NLGN3
uniprot id: A0A6J3DKT1
uniprot id: A0A6J3DN94
uniprot id: A0A6J3DQ18
uniprot id: A0A6J3DR76
uniprot id: A0A6J3DS44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type-B carboxylesterase/lipase family.
messages: Cell membrane
messages: Membrane

219594:SPATS2
gene id: 219594:SPATS2
uniprot id: A0A6J3EC45
uniprot id: A0A6J3EHF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPATS2 family.
messages: Cytoplasm

219594:PROK2
gene id: 219594:PROK2
uniprot id: A0A6J3DJK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AVIT (prokineticin) family.
messages: Secreted

219594:NEUROD2
gene id: 219594:NEUROD2
uniprot id: A0A6J3EBM4
names: Subcellular Location Annotation
messages: Nucleus

219594:ADGRB1
gene id: 219594:ADGRB1
uniprot id: A0A6J3CGQ1
uniprot id: A0A6J3CI93
uniprot id: A0A6J3CI99
uniprot id: A0A6J3CJF3
uniprot id: A0A6J3CJF8
uniprot id: A0A6J3CL88
uniprot id: A0A6J3CL93
uniprot id: A0A6J3CMW6
uniprot id: A0A6J3CMX1
names: Subcellular Location Annotation
messages: Membrane

219594:GCH1
gene id: 219594:GCH1
uniprot id: A0A6J3D2W7
names: Similarity
messages: Belongs to the GTP cyclohydrolase I family.

219594:ZFP36L1
gene id: 219594:ZFP36L1
uniprot id: A0A6J3D7H6
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Associates with the cytoplasmic CCR4-NOT deadenylase complex to trigger ARE-containing mRNA deadenylation and decay processes.
messages: Cytoplasm
messages: Nucleus
messages: Zinc-finger RNA-binding protein that destabilizes several cytoplasmic AU-rich element (ARE)-containing mRNA transcripts by promoting their poly(A) tail removal or deadenylation, and hence provide a mechanism for attenuating protein synthesis. Acts as a 3'-untranslated region (UTR) ARE mRNA-binding adapter protein to communicate signaling events to the mRNA decay machinery. Functions by recruiting the CCR4-NOT deadenylase complex and probably other components of the cytoplasmic RNA decay machinery to the bound ARE-containing mRNAs, and hence promotes ARE-mediated mRNA deadenylation and decay processes. Binds to 3'-UTR ARE of numerous mRNAs.

219594:PSEN2
gene id: 219594:PSEN2
uniprot id: A0A6J3CUP2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase A22A family.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Homodimer.
messages: Membrane
messages: Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors.
messages: The PAL motif is required for normal active site conformation.

219594:PHC1
gene id: 219594:PHC1
uniprot id: A0A6J3D7U2
uniprot id: A0A6J3D7V0
uniprot id: A0A6J3DDD9
names: Subcellular Location Annotation
messages: Nucleus

219594:LIMK2
gene id: 219594:LIMK2
uniprot id: A0A6J3DUL6
uniprot id: A0A6J3DWF0
uniprot id: A0A6J3DYQ2
names: Similarity
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family.

219594:DYNC1LI2
gene id: 219594:DYNC1LI2
uniprot id: A0A6J3DMU4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes.
messages: Belongs to the dynein light intermediate chain family.
messages: Homodimer. The cytoplasmic dynein 1 complex consists of two catalytic heavy chains (HCs) and a number of non-catalytic subunits presented by intermediate chains (ICs).
messages: cytoskeleton

219594:NUDT21
gene id: 219594:NUDT21
uniprot id: A0A6J3DK13
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Nudix hydrolase family. CPSF5 subfamily.
messages: Component of the cleavage factor Im (CFIm) complex that functions as an activator of the pre-mRNA 3'-end cleavage and polyadenylation processing required for the maturation of pre-mRNA into functional mRNAs. CFIm contributes to the recruitment of multiprotein complexes on specific sequences on the pre-mRNA 3'-end, so called cleavage and polyadenylation signals (pA signals). Most pre-mRNAs contain multiple pA signals, resulting in alternative cleavage and polyadenylation (APA) producing mRNAs with variable 3'-end formation. The CFIm complex acts as a key regulator of cleavage and polyadenylation site choice during APA through its binding to 5'-UGUA-3' elements localized in the 3'-untranslated region (UTR) for a huge number of pre-mRNAs.
messages: Cytoplasm
messages: Homodimer (via N- and C-terminus); binds RNA as homodimer. Component of the cleavage factor Im (CFIm) complex.
messages: Nucleus

219594:CEP290
gene id: 219594:CEP290
uniprot id: A0A6J3CDT5
uniprot id: A0A6J3CGL8
names: Subcellular Location Annotation
messages: cilium basal body

219594:ISCA2
gene id: 219594:ISCA2
uniprot id: A0A6J3D2P4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HesB/IscA family.
messages: Mitochondrion

219594:PSD
gene id: 219594:PSD
uniprot id: A0A6J3DDT0
names: Subcellular Location Annotation
messages: ruffle membrane

219594:EIF4H
gene id: 219594:EIF4H
uniprot id: A0A6J3DZ68
uniprot id: A0A6J3E3F6
names: Function
names: Subcellular Location Annotation
messages: Stimulates the RNA helicase activity of EIF4A in the translation initiation complex. Binds weakly mRNA.
messages: perinuclear region

219594:DCP1A
gene id: 219594:DCP1A
uniprot id: A0A6J3DK73
names: Similarity
messages: Belongs to the DCP1 family.

219594:LOC116501289
gene id: 219594:LOC116501289
uniprot id: A0A6J3EMS6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:PSAT1
gene id: 219594:PSAT1
uniprot id: A0A6J3EL61
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.

219594:TBC1D24
gene id: 219594:TBC1D24
uniprot id: A0A6J3DPY2
uniprot id: A0A6J3DV69
names: Subcellular Location Annotation
names: Subunit
messages: Cell membrane
messages: Cytoplasmic vesicle membrane
messages: Interacts with ARF6.
messages: Membrane
messages: Presynapse
messages: Synapse

219594:C4H4orf47
gene id: 219594:C4H4orf47
uniprot id: A0A6J3D0B9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0602 family.
messages: centrosome

219594:STAB1
gene id: 219594:STAB1
uniprot id: A0A6J3DFG3
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

219594:MOGAT1
gene id: 219594:MOGAT1
uniprot id: A0A6J3DIW2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the diacylglycerol acyltransferase family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:B3GALT5
gene id: 219594:B3GALT5
uniprot id: A0A6J3DZE5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

219594:WDR4
gene id: 219594:WDR4
uniprot id: A0A6J3DUG4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat TRM82 family.
messages: Forms a heterodimer with the catalytic subunit METTL1.
messages: Nucleus
messages: Required for the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. In the complex, it is required to stabilize and induce conformational changes of the catalytic subunit.

219594:PIEZO2
gene id: 219594:PIEZO2
uniprot id: A0A6J3CHH0
uniprot id: A0A6J3CJ08
uniprot id: A0A6J3CJ13
uniprot id: A0A6J3CK61
uniprot id: A0A6J3CK68
uniprot id: A0A6J3CM14
uniprot id: A0A6J3CM19
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIEZO (TC 1.A.75) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

219594:NCSTN
gene id: 219594:NCSTN
uniprot id: A0A6J3EEM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nicastrin family.
messages: Membrane

219594:EFNB1
gene id: 219594:EFNB1
uniprot id: A0A6J3DNA4
uniprot id: A0A6J3DS57
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ephrin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

219594:ETV5
gene id: 219594:ETV5
uniprot id: A0A6J3DDQ3
uniprot id: A0A6J3DJC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

219594:MYB
gene id: 219594:MYB
uniprot id: A0A6J3CPS5
uniprot id: A0A6J3CRV3
uniprot id: A0A6J3CSG4
uniprot id: A0A6J3CVV4
names: Subcellular Location Annotation
messages: Nucleus

219594:LOC116489820
gene id: 219594:LOC116489820
uniprot id: A0A6J3D1W1
names: Similarity
messages: Belongs to the glycine N-acyltransferase family.

219594:TRABD2B
gene id: 219594:TRABD2B
uniprot id: A0A6J3D8L8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TIKI family.
messages: Cell membrane
messages: Divalent metal cations. Mn(2+) or Co(2+).
messages: Membrane
messages: Metalloprotease that acts as a negative regulator of the Wnt signaling pathway by mediating the cleavage of the N-terminal residues of a subset of Wnt proteins. Following cleavage, Wnt proteins become oxidized and form large disulfide-bond oligomers, leading to their inactivation.

219594:LOC116495144
gene id: 219594:LOC116495144
uniprot id: A0A6J3DPC1
names: Subcellular Location Annotation
messages: Membrane

219594:NDUFAF1
gene id: 219594:NDUFAF1
uniprot id: A0A6J3CYY1
names: Function
names: Similarity
messages: As part of the MCIA complex, involved in the assembly of the mitochondrial complex I.
messages: Belongs to the CIA30 family.

219594:LOC116488779
gene id: 219594:LOC116488779
uniprot id: A0A6J3D087
names: Similarity
names: Subunit
messages: Belongs to the ENDOU family.
messages: Monomer.

219594:ENKUR
gene id: 219594:ENKUR
uniprot id: A0A6J3CK73
names: Subcellular Location Annotation
messages: cilium axoneme

219594:LOC116501995
gene id: 219594:LOC116501995
uniprot id: A0A6J3ENU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L6 tetraspanin family.
messages: Membrane

219594:LAMA2
gene id: 219594:LAMA2
uniprot id: A0A6J3CS01
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: basement membrane

219594:SUPT20H
gene id: 219594:SUPT20H
uniprot id: A0A6J3CTJ2
uniprot id: A0A6J3CVW4
uniprot id: A0A6J3CW55
uniprot id: A0A6J3CW64
uniprot id: A0A6J3CW71
uniprot id: A0A6J3CYJ5
uniprot id: A0A6J3CYM7
uniprot id: A0A6J3CZM2
uniprot id: A0A6J3CZN2
names: Similarity
messages: Belongs to the SPT20 family.

219594:MAP1LC3C
gene id: 219594:MAP1LC3C
uniprot id: A0A6J3CPU1
names: Similarity
messages: Belongs to the ATG8 family.

219594:MAP2
gene id: 219594:MAP2
uniprot id: A0A6J3D4M4
uniprot id: A0A6J3D4N1
uniprot id: A0A6J3D4N4
uniprot id: A0A6J3D4N9
uniprot id: A0A6J3D7A6
uniprot id: A0A6J3D7B1
uniprot id: A0A6J3D7B8
uniprot id: A0A6J3D7C4
uniprot id: A0A6J3D7T8
uniprot id: A0A6J3D7U3
uniprot id: A0A6J3D7U8
uniprot id: A0A6J3D7V3
uniprot id: A0A6J3DA01
uniprot id: A0A6J3DA07
uniprot id: A0A6J3DA12
uniprot id: A0A6J3DAJ6
uniprot id: A0A6J3DAK1
uniprot id: A0A6J3DAL4
uniprot id: A0A6J3DAL8
names: Subcellular Location Annotation
messages: cytoskeleton

219594:RELL2
gene id: 219594:RELL2
uniprot id: A0A6J3DQY0
names: Similarity
messages: Belongs to the RELT family.

219594:AGBL1
gene id: 219594:AGBL1
uniprot id: A0A6J3DNJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M14 family.
messages: cytosol

219594:DYNC2LI1
gene id: 219594:DYNC2LI1
uniprot id: A0A6J3CSJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dynein light intermediate chain family.
messages: centrosome
messages: cilium
messages: cilium axoneme
messages: cilium basal body

219594:SEPTIN9
gene id: 219594:SEPTIN9
uniprot id: A0A6J3DVX8
uniprot id: A0A6J3E039
uniprot id: A0A6J3E0X3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
messages: Cytoplasm

219594:LOC116500122
gene id: 219594:LOC116500122
uniprot id: A0A6J3EHU7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:CREB3L3
gene id: 219594:CREB3L3
uniprot id: A0A6J3E808
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. ATF subfamily.
messages: Endoplasmic reticulum membrane
messages: Membrane

219594:PHKA2
gene id: 219594:PHKA2
uniprot id: A0A6J3EAZ6
uniprot id: A0A6J3EB08
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Although the final Cys may be farnesylated, the terminal tripeptide is probably not removed, and the C-terminus is not methylated.
messages: Belongs to the phosphorylase b kinase regulatory chain family.
messages: Cell membrane
messages: Membrane
messages: Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. The alpha chain may bind calmodulin.

219594:FAM76B
gene id: 219594:FAM76B
uniprot id: A0A6J3EIF4
uniprot id: A0A6J3EJQ7
uniprot id: A0A6J3ENK7
uniprot id: A0A6J3EQ33
names: Similarity
messages: Belongs to the FAM76 family.

219594:SOX11
gene id: 219594:SOX11
uniprot id: A0A6J3CP70
names: Subcellular Location Annotation
messages: Nucleus

219594:LOC116485394
gene id: 219594:LOC116485394
uniprot id: A0A6J3CC62
names: Similarity
names: Subunit
messages: Belongs to the avian keratin family.
messages: The avian keratins (F-ker, S-ker, C-ker and B-ker) are a complex mixture of very similar polypeptides.

219594:TSTA3
gene id: 219594:TSTA3
uniprot id: A0A6J3CFJ5
uniprot id: A0A6J3CH66
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. Fucose synthase subfamily.
messages: Catalyzes the two-step NADP-dependent conversion of GDP-4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction.

219594:LIX1L
gene id: 219594:LIX1L
uniprot id: A0A6J3EF14
names: Similarity
messages: Belongs to the LIX1 family.

219594:PHB2
gene id: 219594:PHB2
uniprot id: A0A6J3EME2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prohibitin family.
messages: Cell membrane
messages: Mitochondrion inner membrane

219594:DEGS2
gene id: 219594:DEGS2
uniprot id: A0A6J3D3N2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acid desaturase type 1 family. DEGS subfamily.
messages: Endoplasmic reticulum membrane
messages: Membrane

219594:DTX2
gene id: 219594:DTX2
uniprot id: A0A6J3E124
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Deltex family.
messages: Cytoplasm

219594:OVCA2
gene id: 219594:OVCA2
uniprot id: A0A6J3E0S9
names: Similarity
messages: Belongs to the LovG family.

219594:LOC116498416
gene id: 219594:LOC116498416
uniprot id: A0A6J3E9K7
names: Similarity
messages: Belongs to the intermediate filament family.

219594:LOC116499638
gene id: 219594:LOC116499638
uniprot id: A0A6J3EEI3
uniprot id: A0A6J3EG69
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EMC4 family.
messages: Component of the ER membrane protein complex (EMC).
messages: Endoplasmic reticulum membrane
messages: Membrane

219594:PEX12
gene id: 219594:PEX12
uniprot id: A0A6J3E0L5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pex2/pex10/pex12 family.
messages: Peroxisome membrane
messages: Required for protein import into peroxisomes.

219594:MAN1A2
gene id: 219594:MAN1A2
uniprot id: A0A6J3CKD0
names: Similarity
messages: Belongs to the glycosyl hydrolase 47 family.

219594:RANBP9
gene id: 219594:RANBP9
uniprot id: A0A6J3CE08
uniprot id: A0A6J3CK83
names: Similarity
messages: Belongs to the RANBP9/10 family.

219594:LOC116501848
gene id: 219594:LOC116501848
uniprot id: A0A6J3EN90
names: Similarity
messages: Belongs to the peptidase M10A family.

219594:PKP4
gene id: 219594:PKP4
uniprot id: A0A6J3D7V6
uniprot id: A0A6J3D8D2
names: Similarity
messages: Belongs to the beta-catenin family.

219594:TAF1D
gene id: 219594:TAF1D
uniprot id: A0A6J3ED21
uniprot id: A0A6J3ED28
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Component of the transcription factor SL1/TIF-IB complex, composed of TBP and at least TAF1A, TAF1B, TAF1C and TAF1D. Interacts with UBTF.
messages: Component of the transcription factor SL1/TIF-IB complex, which is involved in the assembly of the PIC (preinitiation complex) during RNA polymerase I-dependent transcription. The rate of PIC formation probably is primarily dependent on the rate of association of SL1/TIF-IB with the rDNA promoter. SL1/TIF-IB is involved in stabilization of nucleolar transcription factor 1/UBTF on rDNA. Formation of SL1/TIF-IB excludes the association of TBP with TFIID subunits.
messages: Nucleus

219594:MIPEP
gene id: 219594:MIPEP
uniprot id: A0A6J3D872
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

219594:LOC116496971
gene id: 219594:LOC116496971
uniprot id: A0A6J3DY50
uniprot id: A0A6J3DY56
uniprot id: A0A6J3DZV1
uniprot id: A0A6J3DZV6
uniprot id: A0A6J3E2C3
uniprot id: A0A6J3E354
uniprot id: A0A6J3E358
uniprot id: A0A6J3E363
uniprot id: A0A6J3E481
uniprot id: A0A6J3E485
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. CACNA1B subfamily.
messages: Membrane
messages: Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This alpha-1B subunit gives rise to N-type calcium currents. N-type calcium channels belong to the 'high-voltage activated' (HVA) group. They are involved in pain signaling. Calcium channels containing alpha-1B subunit may play a role in directed migration of immature neurons.

219594:CD2
gene id: 219594:CD2
uniprot id: A0A6J3DSX5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

219594:LOC116491449
gene id: 219594:LOC116491449
uniprot id: A0A6J3DAP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AB hydrolase superfamily. Lipase family.
messages: Secreted

219594:PLPPR5
gene id: 219594:PLPPR5
uniprot id: A0A6J3D8J9
uniprot id: A0A6J3DEA3
uniprot id: A0A6J3DEK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Membrane

219594:PGAM1
gene id: 219594:PGAM1
uniprot id: A0A6J3DD83
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.

219594:SLC44A5
gene id: 219594:SLC44A5
uniprot id: A0A6J3DFL0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CTL (choline transporter-like) family.
messages: Cell membrane
messages: Choline transporter.
messages: Membrane

219594:LOC116500188
gene id: 219594:LOC116500188
uniprot id: A0A6J3EBF0
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

219594:NIPA1
gene id: 219594:NIPA1
uniprot id: A0A6J3ERR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NIPA family.
messages: Membrane

219594:HMGN5
gene id: 219594:HMGN5
uniprot id: A0A6J3DP22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HMGN family.
messages: Nucleus

219594:LOC116494550
gene id: 219594:LOC116494550
uniprot id: A0A6J3DRW2
names: Similarity
messages: Belongs to the centrin family.

219594:EPHB2
gene id: 219594:EPHB2
uniprot id: A0A6J3E690
uniprot id: A0A6J3E7E2
names: Subcellular Location Annotation
messages: Membrane

219594:TRMT2B
gene id: 219594:TRMT2B
uniprot id: A0A6J3DSS5
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:DIS3
gene id: 219594:DIS3
uniprot id: A0A6J3ENI8
uniprot id: A0A6J3EQ12
names: Similarity
messages: Belongs to the RNR ribonuclease family.

219594:CNKSR2
gene id: 219594:CNKSR2
uniprot id: A0A6J3E3B7
uniprot id: A0A6J3E4I9
uniprot id: A0A6J3E4N6
uniprot id: A0A6J3E7K0
uniprot id: A0A6J3E7L6
uniprot id: A0A6J3E863
uniprot id: A0A6J3E9J7
uniprot id: A0A6J3E9P2
names: Similarity
messages: Belongs to the CNKSR family.

219594:HOXD11
gene id: 219594:HOXD11
uniprot id: A0A6J3DAQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus

219594:PPP1R1B
gene id: 219594:PPP1R1B
uniprot id: A0A6J3E440
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein phosphatase inhibitor 1 family.
messages: Cytoplasm
messages: Inhibitor of protein-phosphatase 1.

219594:AGTR1
gene id: 219594:AGTR1
uniprot id: A0A6J3DGI2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for angiotensin II, a vasoconstricting peptide, which acts as a key regulator of blood pressure and sodium retention by the kidney. The activated receptor in turn couples to G-alpha proteins G(q) and thus activates phospholipase C and increases the cytosolic Ca(2+) concentrations, which in turn triggers cellular responses such as stimulation of protein kinase C.

219594:LMF2
gene id: 219594:LMF2
uniprot id: A0A6J3DRT3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lipase maturation factor family.
messages: Endoplasmic reticulum membrane
messages: Involved in the maturation of specific proteins in the endoplasmic reticulum.
messages: Membrane

219594:LOC116500331
gene id: 219594:LOC116500331
uniprot id: A0A6J3EBT5
names: Subcellular Location Annotation
messages: Membrane

219594:POU3F3
gene id: 219594:POU3F3
uniprot id: A0A6J3EJ12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POU transcription factor family. Class-3 subfamily.
messages: Nucleus

219594:DUSP4
gene id: 219594:DUSP4
uniprot id: A0A6J3CV37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
messages: Nucleus

219594:ST6GALNAC3
gene id: 219594:ST6GALNAC3
uniprot id: A0A6J3DGY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

219594:TAFA2
gene id: 219594:TAFA2
uniprot id: A0A6J3EK41
uniprot id: A0A6J3ELJ6
uniprot id: A0A6J3EQR8
uniprot id: A0A6J3ES17
names: Similarity
messages: Belongs to the TAFA family.

219594:TUBB3
gene id: 219594:TUBB3
uniprot id: A0A6J3DQV4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: cytoskeleton

219594:LOC116497625
gene id: 219594:LOC116497625
uniprot id: A0A6J3E7G9
names: Subcellular Location Annotation
messages: Membrane

219594:RPF1
gene id: 219594:RPF1
uniprot id: A0A6J3DGS0
names: Subcellular Location Annotation
messages: nucleolus

219594:SCAMP4
gene id: 219594:SCAMP4
uniprot id: A0A6J3E743
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCAMP family.
messages: Membrane

219594:TMTC2
gene id: 219594:TMTC2
uniprot id: A0A6J3CHI0
uniprot id: A0A6J3CJ25
uniprot id: A0A6J3CM52
uniprot id: A0A6J3CNL5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMTC family.
messages: Endoplasmic reticulum
messages: Membrane

219594:DDX11
gene id: 219594:DDX11
uniprot id: A0A6J3EP83
names: Similarity
messages: Belongs to the DEAD box helicase family. DEAH subfamily. DDX11/CHL1 sub-subfamily.

219594:MTRF1L
gene id: 219594:MTRF1L
uniprot id: A0A6J3CNU3
uniprot id: A0A6J3CQS4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Mitochondrion

219594:LOC116488301
gene id: 219594:LOC116488301
uniprot id: A0A6J3CWH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM47 family.
messages: Membrane

219594:HAGH
gene id: 219594:HAGH
uniprot id: A0A6J3DPH8
uniprot id: A0A6J3DRS5
names: Similarity
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.

219594:PEX16
gene id: 219594:PEX16
uniprot id: A0A6J3CXV3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxin-16 family.
messages: Peroxisome membrane

219594:LOC116499746
gene id: 219594:LOC116499746
uniprot id: A0A6J3EGL1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dwarfin/SMAD family.
messages: Cytoplasm
messages: Nucleus

219594:POMT2
gene id: 219594:POMT2
uniprot id: A0A6J3D3V7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 39 family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Transfers mannose from Dol-P-mannose to Ser or Thr residues on proteins.

219594:ESD
gene id: 219594:ESD
uniprot id: A0A6J3EPK0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the esterase D family.
messages: Cytoplasmic vesicle
messages: Serine hydrolase involved in the detoxification of formaldehyde.

219594:ACER3
gene id: 219594:ACER3
uniprot id: A0A6J3EP09
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alkaline ceramidase family.
messages: Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid.
messages: Membrane

219594:OTOP2
gene id: 219594:OTOP2
uniprot id: A0A6J3DWM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the otopetrin family.
messages: Cell membrane
messages: Membrane

219594:ADGRF5
gene id: 219594:ADGRF5
uniprot id: A0A6J3CTD8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily.
messages: Membrane

219594:PEX13
gene id: 219594:PEX13
uniprot id: A0A6J3CRJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxin-13 family.
messages: Membrane
messages: Peroxisome membrane

219594:UCKL1
gene id: 219594:UCKL1
uniprot id: A0A6J3DUQ9
names: Similarity
messages: Belongs to the uridine kinase family.

219594:CHRM3
gene id: 219594:CHRM3
uniprot id: A0A6J3CS60
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Muscarinic acetylcholine receptor subfamily.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is Pi turnover.

219594:FICD
gene id: 219594:FICD
uniprot id: A0A6J3DZ67
names: Similarity
messages: Belongs to the fic family.

219594:ADA
gene id: 219594:ADA
uniprot id: A0A6J3DSE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.
messages: Cell junction
messages: Cell membrane
messages: Cytoplasmic vesicle lumen

219594:CPEB3
gene id: 219594:CPEB3
uniprot id: A0A6J3D887
uniprot id: A0A6J3DAY5
uniprot id: A0A6J3DBS5
uniprot id: A0A6J3DE66
uniprot id: A0A6J3DE71
names: Similarity
messages: Belongs to the RRM CPEB family.

219594:SLIT1
gene id: 219594:SLIT1
uniprot id: A0A6J3D5T9
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

219594:LOC116490259
gene id: 219594:LOC116490259
uniprot id: A0A6J3D1K5
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

219594:TLCD1
gene id: 219594:TLCD1
uniprot id: A0A6J3E3M0
names: Subcellular Location Annotation
messages: Membrane

219594:RRAD
gene id: 219594:RRAD
uniprot id: A0A6J3DN91
names: Similarity
messages: Belongs to the small GTPase superfamily. RGK family.

219594:WEE2
gene id: 219594:WEE2
uniprot id: A0A6J3EPR4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. WEE1 subfamily.
messages: Binds 2 magnesium ions per subunit.
messages: Nucleus

219594:LCLAT1
gene id: 219594:LCLAT1
uniprot id: A0A6J3CRM2
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

219594:TADA2B
gene id: 219594:TADA2B
uniprot id: A0A6J3CWZ8
names: Subcellular Location Annotation
messages: Nucleus

219594:STMN3
gene id: 219594:STMN3
uniprot id: A0A6J3DX80
names: Similarity
messages: Belongs to the stathmin family.

219594:TRAF2
gene id: 219594:TRAF2
uniprot id: A0A6J3DXM5
uniprot id: A0A6J3DXM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TNF receptor-associated factor family.
messages: Cytoplasm

219594:P2RX7
gene id: 219594:P2RX7
uniprot id: A0A6J3DVY6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P2X receptor family.
messages: Membrane
messages: Receptor for ATP that acts as a ligand-gated ion channel.

219594:LOC116499723
gene id: 219594:LOC116499723
uniprot id: A0A6J3EGI6
names: Similarity
names: Subunit
messages: Belongs to the avian keratin family.
messages: The avian keratins (F-ker, S-ker, C-ker and B-ker) are a complex mixture of very similar polypeptides.

219594:LOC116495907
gene id: 219594:LOC116495907
uniprot id: A0A6J3DV02
names: Similarity
messages: Belongs to the FAM83 family.

219594:PDGFD
gene id: 219594:PDGFD
uniprot id: A0A6J3D6X2
uniprot id: A0A6J3D7G4
uniprot id: A0A6J3D9L9
names: Caution
names: Subunit
messages: Homodimer; disulfide-linked. Interacts with PDGFRB homodimers, and with heterodimers formed by PDGFRA and PDGFRB.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:LOC116490394
gene id: 219594:LOC116490394
uniprot id: A0A6J3D4L9
uniprot id: A0A6J3D505
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

219594:RFC2
gene id: 219594:RFC2
uniprot id: A0A6J3E6I0
names: Similarity
messages: Belongs to the activator 1 small subunits family.

219594:LOC116496837
gene id: 219594:LOC116496837
uniprot id: A0A6J3DZA9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the organo anion transporter (TC 2.A.60) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Secreted

219594:EPDR1
gene id: 219594:EPDR1
uniprot id: A0A6J3CGC1
names: Similarity
messages: Belongs to the ependymin family.

219594:LOC116502350
gene id: 219594:LOC116502350
uniprot id: A0A6J3EQG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone H1/H5 family.
messages: Nucleus

219594:TMED3
gene id: 219594:TMED3
uniprot id: A0A6J3DMY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Membrane
messages: cis-Golgi network membrane

219594:RHPN2
gene id: 219594:RHPN2
uniprot id: A0A6J3DMK0
names: Similarity
messages: Belongs to the RHPN family.

219594:E2F1
gene id: 219594:E2F1
uniprot id: A0A6J3DSJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the E2F/DP family.
messages: Nucleus

219594:ZFPM1
gene id: 219594:ZFPM1
uniprot id: A0A6J3DPY8
names: Subcellular Location Annotation
messages: Nucleus

219594:CNOT11
gene id: 219594:CNOT11
uniprot id: A0A6J3E183
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CNOT11 family.
messages: Cytoplasm
messages: Nucleus

219594:MRPL22
gene id: 219594:MRPL22
uniprot id: A0A6J3DSF3
names: Similarity
messages: Belongs to the universal ribosomal protein uL22 family.

219594:PCSK2
gene id: 219594:PCSK2
uniprot id: A0A6J3CSR3
names: Similarity
messages: Belongs to the peptidase S8 family.

219594:CPAMD8
gene id: 219594:CPAMD8
uniprot id: A0A6J3E7F2
uniprot id: A0A6J3EC14
uniprot id: A0A6J3EE73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family.
messages: Secreted

219594:LIPA
gene id: 219594:LIPA
uniprot id: A0A6J3DC06
names: Similarity
messages: Belongs to the AB hydrolase superfamily. Lipase family.

219594:DDB2
gene id: 219594:DDB2
uniprot id: A0A6J3D520
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat DDB2/WDR76 family.
messages: Nucleus

219594:LOC116491258
gene id: 219594:LOC116491258
uniprot id: A0A6J3DCE6
names: Similarity
messages: Belongs to the DEAD box helicase family. DDX21/DDX50 subfamily.

219594:ITGB4
gene id: 219594:ITGB4
uniprot id: A0A6J3DW99
uniprot id: A0A6J3E0G7
uniprot id: A0A6J3E194
uniprot id: A0A6J3E2E0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin beta chain family.
messages: Membrane

219594:FTO
gene id: 219594:FTO
uniprot id: A0A6J3DM29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fto family.
messages: Cytoplasm
messages: Nucleus speckle

219594:OTOG
gene id: 219594:OTOG
uniprot id: A0A6J3D4G3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:LOC116486307
gene id: 219594:LOC116486307
uniprot id: A0A6J3CLN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family.
messages: Cell membrane
messages: Membrane

219594:STAG2
gene id: 219594:STAG2
uniprot id: A0A6J3DMV4
uniprot id: A0A6J3DRM9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SCC3 family.
messages: Chromosome
messages: Component of cohesin complex, a complex required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate.
messages: Nucleus
messages: Part of the cohesin complex which is composed of a heterodimer between a SMC1 protein (SMC1A or SMC1B) and SMC3, which are attached via their hinge domain, and RAD21 which link them at their heads, and one STAG protein.
messages: centromere

219594:G6PC
gene id: 219594:G6PC
uniprot id: A0A6J3E6H5
uniprot id: A0A6J3E9H7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glucose-6-phosphatase family.
messages: Endoplasmic reticulum membrane

219594:LAPTM4B
gene id: 219594:LAPTM4B
uniprot id: A0A6J3CJP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LAPTM4/LAPTM5 transporter family.
messages: Cell membrane
messages: Endomembrane system
messages: Endosome membrane
messages: Late endosome membrane
messages: Membrane
messages: multivesicular body lumen
messages: multivesicular body membrane

219594:MYO1H
gene id: 219594:MYO1H
uniprot id: A0A6J3DWE5
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

219594:ST18
gene id: 219594:ST18
uniprot id: A0A6J3CQE1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MYT1 family.
messages: Nucleus

219594:SMG8
gene id: 219594:SMG8
uniprot id: A0A6J3E4N2
names: Function
names: Similarity
messages: Belongs to the SMG8 family.
messages: Involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons.

219594:GCN1
gene id: 219594:GCN1
uniprot id: A0A6J3DTH4
names: Similarity
messages: Belongs to the GCN1 family.

219594:CACNG1
gene id: 219594:CACNG1
uniprot id: A0A6J3DZH1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
messages: Component of a calcium channel complex consisting of a pore-forming alpha subunit (CACNA1S) and the ancillary subunits CACNB1 or CACNB2, CACNG1 and CACNA2D1. The channel complex contains alpha, beta, gamma and delta subunits in a 1:1:1:1 ratio, i.e. it contains either CACNB1 or CACNB2.
messages: Membrane
messages: Regulatory subunit of the voltage-gated calcium channel that gives rise to L-type calcium currents in skeletal muscle. Regulates channel inactivation kinetics.
messages: sarcolemma

219594:SCNN1G
gene id: 219594:SCNN1G
uniprot id: A0A6J3DPW3
names: Subcellular Location Annotation
messages: Membrane

219594:UBR3
gene id: 219594:UBR3
uniprot id: A0A6J3D5F3
names: Function
names: Similarity
messages: Belongs to the UBR1 family.
messages: Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.

219594:LOC116493826
gene id: 219594:LOC116493826
uniprot id: A0A6J3DNX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF4 family.
messages: Nucleus

219594:DNAJC16
gene id: 219594:DNAJC16
uniprot id: A0A6J3E667
names: Subcellular Location Annotation
messages: Membrane

219594:ANO9
gene id: 219594:ANO9
uniprot id: A0A6J3D0A3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anoctamin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

219594:DENND6B
gene id: 219594:DENND6B
uniprot id: A0A6J3EJ32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DENND6 family.
messages: Endosome
messages: Recycling endosome

219594:RPE
gene id: 219594:RPE
uniprot id: A0A6J3D7I8
names: Cofactor
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.

219594:FCF1
gene id: 219594:FCF1
uniprot id: A0A6J3D1Q0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UTP23/FCF1 family. FCF1 subfamily.
messages: nucleolus

219594:PDE6B
gene id: 219594:PDE6B
uniprot id: A0A6J3EEW0
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

219594:PHAX
gene id: 219594:PHAX
uniprot id: A0A6J3EJ78
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PHAX family.
messages: Cytoplasm

219594:LOC116493524
gene id: 219594:LOC116493524
uniprot id: A0A6J3DNH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:LOC116492644
gene id: 219594:LOC116492644
uniprot id: A0A6J3DD28
uniprot id: A0A6J3DIM1
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

219594:CADM3
gene id: 219594:CADM3
uniprot id: A0A6J3E9G7
uniprot id: A0A6J3EG94
names: Similarity
messages: Belongs to the nectin family.

219594:SFXN1
gene id: 219594:SFXN1
uniprot id: A0A6J3DTV3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sideroflexin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Mitochondrion membrane

219594:SLC25A24
gene id: 219594:SLC25A24
uniprot id: A0A6J3D9W6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

219594:ANKRD13A
gene id: 219594:ANKRD13A
uniprot id: A0A6J3DU51
names: Function
names: Subcellular Location Annotation
messages: Endosome
messages: Late endosome
messages: Membrane
messages: Ubiquitin-binding protein that specifically recognizes and binds 'Lys-63'-linked ubiquitin. Does not bind 'Lys-48'-linked ubiquitin. Positively regulates the internalization of ligand-activated EGFR by binding to the Ub moiety of ubiquitinated EGFR at the cell membrane.

219594:DCLK2
gene id: 219594:DCLK2
uniprot id: A0A6J3CUK6
uniprot id: A0A6J3CV21
uniprot id: A0A6J3CXC4
uniprot id: A0A6J3CYG4
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily.

219594:TSEN54
gene id: 219594:TSEN54
uniprot id: A0A6J3E1L5
names: Similarity
messages: Belongs to the SEN54 family.

219594:SARM1
gene id: 219594:SARM1
uniprot id: A0A6J3E584
names: Similarity
messages: Belongs to the SARM1 family.

219594:TENT5B
gene id: 219594:TENT5B
uniprot id: A0A6J3EAF1
names: Similarity
messages: Belongs to the TENT family.

219594:TMEM39A
gene id: 219594:TMEM39A
uniprot id: A0A6J3D604
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM39 family.
messages: Membrane

219594:TNKS2
gene id: 219594:TNKS2
uniprot id: A0A6J3DBT1
names: Similarity
messages: Belongs to the ARTD/PARP family.

219594:RPL27
gene id: 219594:RPL27
uniprot id: A0A6J3E4L1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic ribosomal protein eL27 family.
messages: Endoplasmic reticulum
messages: Rough endoplasmic reticulum

219594:PPP2R2D
gene id: 219594:PPP2R2D
uniprot id: A0A6J3D9K7
names: Similarity
messages: Belongs to the phosphatase 2A regulatory subunit B family.

219594:TMEM214
gene id: 219594:TMEM214
uniprot id: A0A6J3CQN0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TMEM214 family.
messages: Constitutively interacts with CASP4; required for the localization of procaspase 4 to the ER.
messages: Critical mediator, in cooperation with CASP4, of endoplasmic reticulum-stress induced apoptosis. Required or the activation of CASP4 following endoplasmic reticulum stress.
messages: Endoplasmic reticulum membrane
messages: Membrane

219594:NFE2L1
gene id: 219594:NFE2L1
uniprot id: A0A6J3EAZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. CNC subfamily.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Nucleus

219594:LOC116489378
gene id: 219594:LOC116489378
uniprot id: A0A6J3CZA0
names: Similarity
messages: Belongs to the globin family.

219594:MACO1
gene id: 219594:MACO1
uniprot id: A0A6J3E861
uniprot id: A0A6J3E9K2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the macoilin family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Nucleus membrane
messages: Rough endoplasmic reticulum membrane

219594:RHCG
gene id: 219594:RHCG
uniprot id: A0A6J3DM84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonium transporter (TC 2.A.49) family. Rh subfamily.
messages: Membrane

219594:NME3
gene id: 219594:NME3
uniprot id: A0A6J3DRM7
names: Similarity
messages: Belongs to the NDK family.

219594:LAMTOR2
gene id: 219594:LAMTOR2
uniprot id: A0A6J3E9K1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GAMAD family.
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane

219594:LMBR1
gene id: 219594:LMBR1
uniprot id: A0A6J3CEV5
names: Similarity
messages: Belongs to the LIMR family.

219594:NOS3
gene id: 219594:NOS3
uniprot id: A0A6J3CMH6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NOS family.
messages: Binds 1 FAD.
messages: Binds 1 FMN.
messages: Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body.

219594:IFNGR1
gene id: 219594:IFNGR1
uniprot id: A0A6J3CSP1
names: Similarity
messages: Belongs to the type II cytokine receptor family.

219594:EIF4E3
gene id: 219594:EIF4E3
uniprot id: A0A6J3DIL1
uniprot id: A0A6J3DLZ4
names: Similarity
messages: Belongs to the eukaryotic initiation factor 4E family.

219594:FAM8A1
gene id: 219594:FAM8A1
uniprot id: A0A6J3CHQ4
names: Subcellular Location Annotation
messages: Membrane

219594:ERBB2
gene id: 219594:ERBB2
uniprot id: A0A6J3E9R9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. EGF receptor subfamily.
messages: Membrane

219594:AMIGO2
gene id: 219594:AMIGO2
uniprot id: A0A6J3EP66
names: Similarity
messages: Belongs to the immunoglobulin superfamily. AMIGO family.

219594:SPAST
gene id: 219594:SPAST
uniprot id: A0A6J3CPK6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent microtubule severing protein that specifically recognizes and cuts microtubules that are polyglutamylated. Preferentially recognizes and acts on microtubules decorated with short polyglutamate tails: severing activity increases as the number of glutamates per tubulin rises from one to eight, but decreases beyond this glutamylation threshold. Microtubule severing promotes reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Required for membrane traffic from the endoplasmic reticulum (ER) to the Golgi and for completion of the abscission stage of cytokinesis. Also plays a role in axon growth and the formation of axonal branches.
messages: Belongs to the AAA ATPase family. Spastin subfamily.
messages: Homohexamer. The homohexamer is stabilized by ATP-binding. The homohexamer may adopt a ring conformation through which microtubules pass prior to being severed. Interacts with microtubules.
messages: Membrane
messages: Nucleus
messages: axon
messages: centrosome
messages: cytoskeleton
messages: perinuclear region

219594:CARTPT
gene id: 219594:CARTPT
uniprot id: A0A6J3EG65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CART family.
messages: Secreted

219594:PALMD
gene id: 219594:PALMD
uniprot id: A0A6J3DH20
names: Similarity
messages: Belongs to the paralemmin family.

219594:AP1G1
gene id: 219594:AP1G1
uniprot id: A0A6J3DJJ0
names: Similarity
messages: Belongs to the adaptor complexes large subunit family.

219594:BARX2
gene id: 219594:BARX2
uniprot id: A0A6J3E6Z2
names: Subcellular Location Annotation
messages: Nucleus

219594:LOC116485357
gene id: 219594:LOC116485357
uniprot id: A0A6J3CC15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM170 family.
messages: Membrane

219594:LOC116498566
gene id: 219594:LOC116498566
uniprot id: A0A6J3E9K8
names: Similarity
names: Subunit
messages: Belongs to the avian keratin family.
messages: The avian keratins (F-ker, S-ker, C-ker and B-ker) are a complex mixture of very similar polypeptides.

219594:ARR3
gene id: 219594:ARR3
uniprot id: A0A6J3DLK4
names: Function
names: Similarity
messages: Belongs to the arrestin family.
messages: May play a role in an as yet undefined retina-specific signal transduction. Could bind to photoactivated-phosphorylated red/green opsins.

219594:TAFA1
gene id: 219594:TAFA1
uniprot id: A0A6J3DEW4
names: Similarity
messages: Belongs to the TAFA family.

219594:LOC116494024
gene id: 219594:LOC116494024
uniprot id: A0A6J3DQL2
names: Similarity
messages: Belongs to the arylamine N-acetyltransferase family.

219594:IST1
gene id: 219594:IST1
uniprot id: A0A6J3DMA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IST1 family.
messages: Cytoplasmic vesicle
messages: Nucleus envelope

219594:LOC116490254
gene id: 219594:LOC116490254
uniprot id: A0A6J3D3Y2
names: Function
names: Similarity
messages: Belongs to the SAA family.
messages: Major acute phase reactant. Apolipoprotein of the HDL complex.

219594:SLC35D1
gene id: 219594:SLC35D1
uniprot id: A0A6J3DFH1
names: Subcellular Location Annotation
messages: Membrane

219594:DNAAF2
gene id: 219594:DNAAF2
uniprot id: A0A6J3D5Y7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIH1 family. Kintoun subfamily.
messages: Cytoplasm
messages: Required for cytoplasmic pre-assembly of axonemal dyneins, thereby playing a central role in motility in cilia and flagella. Involved in pre-assembly of dynein arm complexes in the cytoplasm before intraflagellar transport loads them for the ciliary compartment.

219594:PPIF
gene id: 219594:PPIF
uniprot id: A0A6J3D996
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

219594:TPH2
gene id: 219594:TPH2
uniprot id: A0A6J3DTG4
names: Similarity
messages: Belongs to the biopterin-dependent aromatic amino acid hydroxylase family.

219594:PPCS
gene id: 219594:PPCS
uniprot id: A0A6J3E622
names: Similarity
messages: Belongs to the PPC synthetase family.

219594:LOC116491006
gene id: 219594:LOC116491006
uniprot id: A0A6J3D8H4
names: Similarity
messages: Belongs to the peptidase C14A family.

219594:HOXC10
gene id: 219594:HOXC10
uniprot id: A0A6J3EBZ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus

219594:ABLIM1
gene id: 219594:ABLIM1
uniprot id: A0A6J3D5L8
uniprot id: A0A6J3D5M2
uniprot id: A0A6J3D8B1
uniprot id: A0A6J3D8B7
uniprot id: A0A6J3D8U2
uniprot id: A0A6J3D8U5
uniprot id: A0A6J3DB02
uniprot id: A0A6J3DB08
uniprot id: A0A6J3DB13
uniprot id: A0A6J3DBI6
names: Subcellular Location Annotation
messages: Cytoplasm

219594:BNIP3
gene id: 219594:BNIP3
uniprot id: A0A6J3DDR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NIP3 family.
messages: Membrane

219594:NT5E
gene id: 219594:NT5E
uniprot id: A0A6J3CLB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 5'-nucleotidase family.
messages: Membrane

219594:NUCB2
gene id: 219594:NUCB2
uniprot id: A0A6J3D4P8
names: Similarity
messages: Belongs to the nucleobindin family.

219594:PFDN4
gene id: 219594:PFDN4
uniprot id: A0A6J3DU00
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prefoldin subunit beta family.
messages: Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins.
messages: Heterohexamer of two PFD-alpha type and four PFD-beta type subunits.

219594:GLOD4
gene id: 219594:GLOD4
uniprot id: A0A6J3E006
names: Similarity
messages: Belongs to the glyoxalase I family.

219594:SPARC
gene id: 219594:SPARC
uniprot id: A0A6J3DMK4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Appears to regulate cell growth through interactions with the extracellular matrix and cytokines. Binds calcium and copper, several types of collagen, albumin, thrombospondin, PDGF and cell membranes. There are two calcium binding sites; an acidic domain that binds 5 to 8 Ca(2+) with a low affinity and an EF-hand loop that binds a Ca(2+) ion with a high affinity.
messages: Belongs to the SPARC family.
messages: Membrane
messages: basement membrane

219594:CCT7
gene id: 219594:CCT7
uniprot id: A0A6J3D0B5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TCP-1 chaperonin family.
messages: Cytoplasm
messages: Heterooligomeric complex of about 850 to 900 kDa that forms two stacked rings, 12 to 16 nm in diameter.
messages: Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin.

219594:MBTPS2
gene id: 219594:MBTPS2
uniprot id: A0A6J3D0S2
uniprot id: A0A6J3D0T7
names: Similarity
messages: Belongs to the peptidase M50A family.

219594:UCK2
gene id: 219594:UCK2
uniprot id: A0A6J3DFB7
names: Similarity
names: Subunit
messages: Belongs to the uridine kinase family.
messages: Homotetramer.

219594:DYNC1LI1
gene id: 219594:DYNC1LI1
uniprot id: A0A6J3CEU3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes.
messages: Belongs to the dynein light intermediate chain family.
messages: Homodimer. The cytoplasmic dynein 1 complex consists of two catalytic heavy chains (HCs) and a number of non-catalytic subunits presented by intermediate chains (ICs).
messages: cytoskeleton

219594:PRKD1
gene id: 219594:PRKD1
uniprot id: A0A6J3D304
uniprot id: A0A6J3D427
names: Activity Regulation
names: Similarity
names: Subcellular Location Annotation
messages: Activated by DAG and phorbol esters.
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PKD subfamily.
messages: Cytoplasm
messages: Membrane

219594:PDHA1
gene id: 219594:PDHA1
uniprot id: A0A6J3EG30
names: Function
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and thereby links the glycolytic pathway to the tricarboxylic cycle.

219594:TINAG
gene id: 219594:TINAG
uniprot id: A0A6J3CTL9
names: Similarity
messages: Belongs to the peptidase C1 family.

219594:RPUSD2
gene id: 219594:RPUSD2
uniprot id: A0A6J3D4I6
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

219594:CER1
gene id: 219594:CER1
uniprot id: A0A6J3ECT6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DAN family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

219594:DNASE2B
gene id: 219594:DNASE2B
uniprot id: A0A6J3DFZ1
names: Similarity
messages: Belongs to the DNase II family.

219594:GTPBP10
gene id: 219594:GTPBP10
uniprot id: A0A6J3CGR6
uniprot id: A0A6J3CHR6
names: Similarity
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.

219594:SOAT1
gene id: 219594:SOAT1
uniprot id: A0A6J3DA80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family. Sterol o-acyltransferase subfamily.
messages: Endoplasmic reticulum membrane
messages: Membrane

219594:HOXA7
gene id: 219594:HOXA7
uniprot id: A0A6J3CIW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus

219594:PSMC5
gene id: 219594:PSMC5
uniprot id: A0A6J3E9R6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family.
messages: Cytoplasm

219594:RAG2
gene id: 219594:RAG2
uniprot id: A0A6J3CYE7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RAG2 family.
messages: Nucleus

219594:VPS18
gene id: 219594:VPS18
uniprot id: A0A6J3D009
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS18 family.
messages: Membrane

219594:ATP5MC2
gene id: 219594:ATP5MC2
uniprot id: A0A6J3EF75
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Membrane
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. A homomeric c-ring of probably 10 subunits is part of the complex rotary element.
messages: Mitochondrion membrane

219594:CMAS
gene id: 219594:CMAS
uniprot id: A0A6J3DKS7
names: Similarity
messages: Belongs to the CMP-NeuNAc synthase family.

219594:DYSF
gene id: 219594:DYSF
uniprot id: A0A6J3CRV2
uniprot id: A0A6J3CRV8
uniprot id: A0A6J3CU52
uniprot id: A0A6J3CU56
uniprot id: A0A6J3CU61
uniprot id: A0A6J3CU66
uniprot id: A0A6J3CUN0
uniprot id: A0A6J3CUN5
uniprot id: A0A6J3CUP1
uniprot id: A0A6J3CWY4
uniprot id: A0A6J3CWZ2
uniprot id: A0A6J3CWZ7
uniprot id: A0A6J3CY15
uniprot id: A0A6J3CY21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferlin family.
messages: Cytoplasmic vesicle membrane
messages: Membrane

219594:EYS
gene id: 219594:EYS
uniprot id: A0A6J3CWT7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:CDC14A
gene id: 219594:CDC14A
uniprot id: A0A6J3DEW5
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class CDC14 subfamily.

219594:SMC5
gene id: 219594:SMC5
uniprot id: A0A6J3ECG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMC family. SMC5 subfamily.
messages: Chromosome
messages: Nucleus

219594:CCND2
gene id: 219594:CCND2
uniprot id: A0A6J3DKL4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cyclin family. Cyclin D subfamily.
messages: Cytoplasm
messages: Nucleus

219594:MYZAP
gene id: 219594:MYZAP
uniprot id: A0A6J3DMB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GRINL1 family.
messages: Nucleus

219594:LOC116499569
gene id: 219594:LOC116499569
uniprot id: A0A6J3EDT7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Toll-like receptor family.
messages: Membrane

219594:LOC116499136
gene id: 219594:LOC116499136
uniprot id: A0A6J3EEC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

219594:NCDN
gene id: 219594:NCDN
uniprot id: A0A6J3E3B1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neurochondrin family.
messages: Postsynapse

219594:CNEP1R1
gene id: 219594:CNEP1R1
uniprot id: A0A6J3DMH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CNEP1R1 family.
messages: Cytoplasm
messages: Membrane
messages: Nucleus membrane

219594:LOC116494364
gene id: 219594:LOC116494364
uniprot id: A0A6J3DR89
uniprot id: A0A6J3DS67
names: Similarity
messages: Belongs to the EVA1 family.

219594:MAFK
gene id: 219594:MAFK
uniprot id: A0A6J3DTY8
names: Similarity
messages: Belongs to the bZIP family. Maf subfamily.

219594:REEP3
gene id: 219594:REEP3
uniprot id: A0A6J3D9T7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DP1 family.
messages: Membrane

219594:STXBP1
gene id: 219594:STXBP1
uniprot id: A0A6J3DZB8
uniprot id: A0A6J3E3N7
names: Similarity
messages: Belongs to the STXBP/unc-18/SEC1 family.

219594:LRP1
gene id: 219594:LRP1
uniprot id: A0A6J3EAU0
uniprot id: A0A6J3EFW2
names: Caution
names: Similarity
messages: Belongs to the LDLR family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:LOC116496287
gene id: 219594:LOC116496287
uniprot id: A0A6J3DUX2
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

219594:GBF1
gene id: 219594:GBF1
uniprot id: A0A6J3D7U7
uniprot id: A0A6J3DAI2
uniprot id: A0A6J3DB91
uniprot id: A0A6J3DDE9
uniprot id: A0A6J3DDS4
names: Subcellular Location Annotation
messages: Golgi apparatus

219594:SGCG
gene id: 219594:SGCG
uniprot id: A0A6J3DVK9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sarcoglycan beta/delta/gamma/zeta family.
messages: Component of the sarcoglycan complex, a subcomplex of the dystrophin-glycoprotein complex which forms a link between the F-actin cytoskeleton and the extracellular matrix.
messages: cytoskeleton
messages: sarcolemma

219594:SLC35B2
gene id: 219594:SLC35B2
uniprot id: A0A6J3CL34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide-sugar transporter family. SLC35B subfamily.
messages: Membrane

219594:LOXHD1
gene id: 219594:LOXHD1
uniprot id: A0A6J3EKJ9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:USP37
gene id: 219594:USP37
uniprot id: A0A6J3D550
uniprot id: A0A6J3D8C2
names: Similarity
messages: Belongs to the peptidase C19 family.

219594:TIPARP
gene id: 219594:TIPARP
uniprot id: A0A6J3DHQ2
names: Similarity
messages: Belongs to the ARTD/PARP family.

219594:SEC22B
gene id: 219594:SEC22B
uniprot id: A0A6J3DE24
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Melanosome
messages: Membrane
messages: SNARE involved in targeting and fusion of ER-derived transport vesicles with the Golgi complex as well as Golgi-derived retrograde transport vesicles with the ER.
messages: cis-Golgi network membrane
messages: trans-Golgi network membrane

219594:CCR7
gene id: 219594:CCR7
uniprot id: A0A6J3E6U8
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

219594:KIF17
gene id: 219594:KIF17
uniprot id: A0A6J3E6S3
names: Caution
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:ANKRD34C
gene id: 219594:ANKRD34C
uniprot id: A0A6J3DPG0
names: Similarity
messages: Belongs to the ANKRD34 family.

219594:SLC1A4
gene id: 219594:SLC1A4
uniprot id: A0A6J3CM66
uniprot id: A0A6J3CN96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

219594:FZD7
gene id: 219594:FZD7
uniprot id: A0A6J3D608
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor Fz/Smo family.
messages: Cell membrane
messages: Endosome membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

219594:IL1RL1
gene id: 219594:IL1RL1
uniprot id: A0A6J3E522
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the interleukin-1 receptor family.
messages: axon
messages: dendrite

219594:UPF2
gene id: 219594:UPF2
uniprot id: A0A6J3D912
uniprot id: A0A6J3DEX5
names: Subcellular Location Annotation
messages: Cytoplasm

219594:MOXD1
gene id: 219594:MOXD1
uniprot id: A0A6J3CQ37
uniprot id: A0A6J3CR70
names: Similarity
messages: Belongs to the copper type II ascorbate-dependent monooxygenase family.

219594:LAMB4
gene id: 219594:LAMB4
uniprot id: A0A6J3E035
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: basement membrane

219594:AKAP12
gene id: 219594:AKAP12
uniprot id: A0A6J3CQ00
uniprot id: A0A6J3CSA6
names: Subcellular Location Annotation
messages: Membrane

219594:SELENOS
gene id: 219594:SELENOS
uniprot id: A0A6J3DMA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the selenoprotein S family.
messages: Cytoplasm
messages: Endoplasmic reticulum membrane
messages: Membrane

219594:CKAP2L
gene id: 219594:CKAP2L
uniprot id: A0A6J3ECV5
names: Similarity
messages: Belongs to the CKAP2 family.

219594:EIF4A2
gene id: 219594:EIF4A2
uniprot id: A0A6J3DFL9
names: Similarity
messages: Belongs to the DEAD box helicase family. eIF4A subfamily.

219594:LOC116490458
gene id: 219594:LOC116490458
uniprot id: A0A6J3D885
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Cell membrane
messages: Membrane
messages: Membrane raft
messages: Transmembrane serine/threonine kinase forming with the TGF-beta type I serine/threonine kinase receptor, TGFBR1, the non-promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinogenesis. The formation of the receptor complex composed of 2 TGFBR1 and 2 TGFBR2 molecules symmetrically bound to the cytokine dimer results in the phosphorylation and the activation of TGFRB1 by the constitutively active TGFBR2. Activated TGFBR1 phosphorylates SMAD2 which dissociates from the receptor and interacts with SMAD4. The SMAD2-SMAD4 complex is subsequently translocated to the nucleus where it modulates the transcription of the TGF-beta-regulated genes. This constitutes the canonical SMAD-dependent TGF-beta signaling cascade. Also involved in non-canonical, SMAD-independent TGF-beta signaling pathways.

219594:SPCS2
gene id: 219594:SPCS2
uniprot id: A0A6J3EP40
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPCS2 family.
messages: Component of the signal peptidase complex (SPC) which catalyzes the cleavage of N-terminal signal sequences from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum. Enhances the enzymatic activity of SPC and facilitates the interactions between different components of the translocation site.
messages: Endoplasmic reticulum membrane
messages: Membrane

219594:TUBD1
gene id: 219594:TUBD1
uniprot id: A0A6J3E4C6
uniprot id: A0A6J3E574
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Nucleus
messages: centriole
messages: cilium

219594:SIX3
gene id: 219594:SIX3
uniprot id: A0A6J3CX00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SIX/Sine oculis homeobox family.
messages: Nucleus

219594:MMP9
gene id: 219594:MMP9
uniprot id: A0A6J3DX21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M10A family.
messages: extracellular matrix

219594:GSDME
gene id: 219594:GSDME
uniprot id: A0A6J3CDS3
uniprot id: A0A6J3CJZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gasdermin family.
messages: Cell membrane
messages: Membrane

219594:ZDHHC1
gene id: 219594:ZDHHC1
uniprot id: A0A6J3DLQ1
uniprot id: A0A6J3DPL6
uniprot id: A0A6J3DQB5
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

219594:S1PR3
gene id: 219594:S1PR3
uniprot id: A0A6J3EHP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

219594:OIP5
gene id: 219594:OIP5
uniprot id: A0A6J3D0B3
names: Function
names: Subcellular Location Annotation
messages: Required for recruitment of CENPA to centromeres and normal chromosome segregation during mitosis.
messages: centromere

219594:LOC116485640
gene id: 219594:LOC116485640
uniprot id: A0A6J3CHX8
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.
messages: Membrane
messages: desmosome

219594:BCLAF1
gene id: 219594:BCLAF1
uniprot id: A0A6J3CKU0
uniprot id: A0A6J3CKU5
uniprot id: A0A6J3CME2
names: Similarity
messages: Belongs to the BCLAF1/THRAP3 family.

219594:TUBGCP4
gene id: 219594:TUBGCP4
uniprot id: A0A6J3DNE3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TUBGCP family.
messages: Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome.
messages: centrosome

219594:LOC116487804
gene id: 219594:LOC116487804
uniprot id: A0A6J3CRC2
names: Similarity
messages: Belongs to the heat shock protein 70 family.

219594:INPPL1
gene id: 219594:INPPL1
uniprot id: A0A6J3EQM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inositol 1,4,5-trisphosphate 5-phosphatase family.
messages: Membrane
messages: Nucleus speckle
messages: filopodium
messages: lamellipodium

219594:LMBR1L
gene id: 219594:LMBR1L
uniprot id: A0A6J3EAQ3
uniprot id: A0A6J3EFG1
uniprot id: A0A6J3EFS7
names: Similarity
messages: Belongs to the LIMR family.

219594:PNN
gene id: 219594:PNN
uniprot id: A0A6J3D293
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pinin family.
messages: Found in a mRNA splicing-dependent exon junction complex (EJC). Found in a complex with SR proteins. Found in a mRNP complex with RNPS1. Component of the PSAP complex consisting of RNPS1, SAP18 and PNN. Interacts with PNISR, CTBP1, CTBP2, KRT8, KRT18, KRT19, PS1D/PNO40, PPIG, RNPS1, SFRS4 and SRRM2. Identified in the spliceosome C complex.
messages: Nucleus speckle
messages: desmosome

219594:PEX1
gene id: 219594:PEX1
uniprot id: A0A6J3CM38
uniprot id: A0A6J3CNN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family.
messages: Cytoplasm

219594:ACAN
gene id: 219594:ACAN
uniprot id: A0A6J3DNP5
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

219594:MRPL13
gene id: 219594:MRPL13
uniprot id: A0A6J3CGB2
names: Similarity
messages: Belongs to the universal ribosomal protein uL13 family.

219594:LOC116486772
gene id: 219594:LOC116486772
uniprot id: A0A6J3CM33
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

219594:LOC116485686
gene id: 219594:LOC116485686
uniprot id: A0A6J3CI27
names: Similarity
names: Subunit
messages: Belongs to the avian keratin family.
messages: The avian keratins (F-ker, S-ker, C-ker and B-ker) are a complex mixture of very similar polypeptides.

219594:MED16
gene id: 219594:MED16
uniprot id: A0A6J3EEK6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 16 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

219594:CD320
gene id: 219594:CD320
uniprot id: A0A6J3ECQ0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:CHEK1
gene id: 219594:CHEK1
uniprot id: A0A6J3E7G1
uniprot id: A0A6J3E8U4
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. NIM1 subfamily.

219594:BZW2
gene id: 219594:BZW2
uniprot id: A0A6J3CFG5
names: Similarity
messages: Belongs to the BZW family.

219594:ERGIC3
gene id: 219594:ERGIC3
uniprot id: A0A6J3DWP7
uniprot id: A0A6J3DXP7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERGIC family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Golgi apparatus membrane
messages: Plays a role in transport between endoplasmic reticulum and Golgi.

219594:VAC14
gene id: 219594:VAC14
uniprot id: A0A6J3DQH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VAC14 family.
messages: Endosome membrane
messages: Microsome membrane

219594:TXLNA
gene id: 219594:TXLNA
uniprot id: A0A6J3E3R6
names: Similarity
messages: Belongs to the taxilin family.

219594:AKAP8L
gene id: 219594:AKAP8L
uniprot id: A0A6J3ECG4
uniprot id: A0A6J3EG52
uniprot id: A0A6J3EHS2
names: Similarity
messages: Belongs to the AKAP95 family.

219594:RAB21
gene id: 219594:RAB21
uniprot id: A0A6J3EPH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Cleavage furrow
messages: Cytoplasmic vesicle membrane
messages: Early endosome membrane
messages: Endoplasmic reticulum membrane
messages: Endosome membrane
messages: neuron projection
messages: trans-Golgi network

219594:FAM214B
gene id: 219594:FAM214B
uniprot id: A0A6J3EHD7
names: Similarity
messages: Belongs to the FAM214 family.

219594:AATF
gene id: 219594:AATF
uniprot id: A0A6J3E1T5
names: Similarity
messages: Belongs to the AATF family.

219594:CDKAL1
gene id: 219594:CDKAL1
uniprot id: A0A6J3CIW1
uniprot id: A0A6J3CKJ8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. CDKAL1 subfamily.
messages: Binds 1 or 2 [4Fe-4S] cluster. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-threonylcarbamoyladenosine (t(6)A), leading to the formation of 2-methylthio-N6-threonylcarbamoyladenosine (ms(2)t(6)A) at position 37 in tRNAs that read codons beginning with adenine.
messages: Endoplasmic reticulum membrane

219594:PIGF
gene id: 219594:PIGF
uniprot id: A0A6J3CPA8
uniprot id: A0A6J3CRL1
uniprot id: A0A6J3CSL4
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

219594:LOC116485793
gene id: 219594:LOC116485793
uniprot id: A0A6J3CFX4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
messages: cytoskeleton

219594:PPP1R9A
gene id: 219594:PPP1R9A
uniprot id: A0A6J3CDL9
uniprot id: A0A6J3CF97
uniprot id: A0A6J3CG98
uniprot id: A0A6J3CI52
names: Subcellular Location Annotation
messages: cytoskeleton

219594:LOC116488953
gene id: 219594:LOC116488953
uniprot id: A0A6J3CXG8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IL-12B family.
messages: Belongs to the type I cytokine receptor family. Type 3 subfamily.
messages: Heterodimer with IL12A; disulfide-linked. The heterodimer is known as interleukin IL-12.
messages: Secreted

219594:FLVCR2
gene id: 219594:FLVCR2
uniprot id: A0A6J3D0C6
uniprot id: A0A6J3D0D8
uniprot id: A0A6J3D2S7
names: Subcellular Location Annotation
messages: Membrane

219594:SDHB
gene id: 219594:SDHB
uniprot id: A0A6J3E1F9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.
messages: Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).
messages: Mitochondrion inner membrane

219594:MTOR
gene id: 219594:MTOR
uniprot id: A0A6J3E6X3
names: Similarity
messages: Belongs to the PI3/PI4-kinase family.

219594:NSG2
gene id: 219594:NSG2
uniprot id: A0A6J3DSM7
names: Similarity
messages: Belongs to the NSG family.

219594:PHETA2
gene id: 219594:PHETA2
uniprot id: A0A6J3DSR0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sesquipedalian family.
messages: Early endosome
messages: Plays a role in endocytic trafficking. Required for receptor recycling from endosomes, both to the trans-Golgi network and the plasma membrane.
messages: Recycling endosome
messages: clathrin-coated vesicle
messages: trans-Golgi network

219594:JAGN1
gene id: 219594:JAGN1
uniprot id: A0A6J3DEP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the jagunal family.
messages: Endoplasmic reticulum membrane
messages: Membrane

219594:LOC116489499
gene id: 219594:LOC116489499
uniprot id: A0A6J3CXM6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:FGG
gene id: 219594:FGG
uniprot id: A0A6J3CW85
names: Subcellular Location Annotation
names: Subunit
messages: Heterohexamer; disulfide linked. Contains 2 sets of 3 non-identical chains (alpha, beta and gamma). The 2 heterotrimers are in head to head conformation with the N-termini in a small central domain.
messages: Secreted

219594:CAPN7
gene id: 219594:CAPN7
uniprot id: A0A6J3CHU7
uniprot id: A0A6J3CJB8
uniprot id: A0A6J3CMG6
names: Similarity
messages: Belongs to the peptidase C2 family.

219594:PAX9
gene id: 219594:PAX9
uniprot id: A0A6J3D569
names: Subcellular Location Annotation
messages: Nucleus

219594:LOC116501909
gene id: 219594:LOC116501909
uniprot id: A0A6J3EIA9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

219594:LOC116487601
gene id: 219594:LOC116487601
uniprot id: A0A6J3CQY5
names: Similarity
messages: Belongs to the COX20 family.

219594:LOC116498321
gene id: 219594:LOC116498321
uniprot id: A0A6J3E979
names: Similarity
names: Subunit
messages: Belongs to the avian keratin family.
messages: The avian keratins (F-ker, S-ker, C-ker and B-ker) are a complex mixture of very similar polypeptides.

219594:GJB7
gene id: 219594:GJB7
uniprot id: A0A6J3CVM6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

219594:SLC41A1
gene id: 219594:SLC41A1
uniprot id: A0A6J3EBH5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Membrane

219594:GPD1L
gene id: 219594:GPD1L
uniprot id: A0A6J3CF36
names: Similarity
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.

219594:HINT2
gene id: 219594:HINT2
uniprot id: A0A6J3EHN4
names: Similarity
messages: Belongs to the HINT family.

219594:MST1
gene id: 219594:MST1
uniprot id: A0A6J3DJ52
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:ARRDC3
gene id: 219594:ARRDC3
uniprot id: A0A6J3EID8
names: Similarity
messages: Belongs to the arrestin family.

219594:LOC116502331
gene id: 219594:LOC116502331
uniprot id: A0A6J3EQH3
names: Subcellular Location Annotation
messages: Nucleus

219594:PDE11A
gene id: 219594:PDE11A
uniprot id: A0A6J3D6F7
uniprot id: A0A6J3D6Y7
uniprot id: A0A6J3D960
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

219594:AMOT
gene id: 219594:AMOT
uniprot id: A0A6J3DL12
names: Similarity
messages: Belongs to the angiomotin family.

219594:GTF2A1
gene id: 219594:GTF2A1
uniprot id: A0A6J3D277
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFIIA subunit 1 family.
messages: Nucleus

219594:GPR50
gene id: 219594:GPR50
uniprot id: A0A6J3DSR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:CHD7
gene id: 219594:CHD7
uniprot id: A0A6J3CEF9
uniprot id: A0A6J3CG30
names: Similarity
messages: Belongs to the SNF2/RAD54 helicase family.

219594:LOC116486736
gene id: 219594:LOC116486736
uniprot id: A0A6J3CNY1
names: Function
names: Similarity
messages: Belongs to the PET191 family.
messages: Involved in an early step of the mitochondrial complex IV assembly process.

219594:NUTF2
gene id: 219594:NUTF2
uniprot id: A0A6J3DPD4
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Has a role in nuclear-cytoplasmic transport of proteins and mRNAs.
messages: Nucleus

219594:TYR
gene id: 219594:TYR
uniprot id: A0A6J3ELG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tyrosinase family.
messages: Melanosome membrane
messages: Membrane

219594:TSPO2
gene id: 219594:TSPO2
uniprot id: A0A6J3E7V1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TspO/BZRP family.
messages: Membrane

219594:ATXN1L
gene id: 219594:ATXN1L
uniprot id: A0A6J3DPM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATXN1 family.
messages: Nucleus

219594:LOC116499252
gene id: 219594:LOC116499252
uniprot id: A0A6J3E9I7
names: Similarity
messages: Belongs to the perilipin family.

219594:SGIP1
gene id: 219594:SGIP1
uniprot id: A0A6J3D974
uniprot id: A0A6J3DBX1
uniprot id: A0A6J3DCV9
uniprot id: A0A6J3DF33
names: Function
names: Subcellular Location Annotation
messages: May function in clathrin-mediated endocytosis. Has both a membrane binding/tubulating activity and the ability to recruit proteins essential to the formation of functional clathrin-coated pits. Has a preference for membranes enriched in phosphatidylserine and phosphoinositides and is required for the endocytosis of the transferrin receptor. May also bind tubulin. May play a role in the regulation of energy homeostasis.
messages: clathrin-coated pit

219594:GALE
gene id: 219594:GALE
uniprot id: A0A6J3E4V8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Catalyzes two distinct but analogous reactions: the reversible epimerization of UDP-glucose to UDP-galactose and the reversible epimerization of UDP-N-acetylglucosamine to UDP-N-acetylgalactosamine. The reaction with UDP-Gal plays a critical role in the Leloir pathway of galactose catabolism in which galactose is converted to the glycolytic intermediate glucose 6-phosphate. It contributes to the catabolism of dietary galactose and enables the endogenous biosynthesis of both UDP-Gal and UDP-GalNAc when exogenous sources are limited. Both UDP-sugar interconversions are important in the synthesis of glycoproteins and glycolipids.
messages: Homodimer.

219594:SIX1
gene id: 219594:SIX1
uniprot id: A0A6J3CY80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SIX/Sine oculis homeobox family.
messages: Cytoplasm
messages: Nucleus

219594:HNRNPH1
gene id: 219594:HNRNPH1
uniprot id: A0A6J3DMC0
uniprot id: A0A6J3DPN2
uniprot id: A0A6J3DRN0
uniprot id: A0A6J3DRN7
uniprot id: A0A6J3DSG7
uniprot id: A0A6J3DTK5
uniprot id: A0A6J3DTL1
names: Subcellular Location Annotation
messages: nucleoplasm

219594:FOXN4
gene id: 219594:FOXN4
uniprot id: A0A6J3DX45
names: Subcellular Location Annotation
messages: Nucleus

219594:TAPT1
gene id: 219594:TAPT1
uniprot id: A0A6J3CU75
uniprot id: A0A6J3CZ90
uniprot id: A0A6J3D0C2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAPT1 family.
messages: Membrane

219594:SLC30A6
gene id: 219594:SLC30A6
uniprot id: A0A6J3CVC4
uniprot id: A0A6J3CWH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
messages: Membrane

219594:PDLIM3
gene id: 219594:PDLIM3
uniprot id: A0A6J3CXG2
uniprot id: A0A6J3CXS2
names: Subcellular Location Annotation
messages: Z line

219594:SZRD1
gene id: 219594:SZRD1
uniprot id: A0A6J3E1Q3
uniprot id: A0A6J3E5Y6
names: Similarity
messages: Belongs to the SZRD1 family.

219594:GOT1
gene id: 219594:GOT1
uniprot id: A0A6J3DDW8
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.
messages: In eukaryotes there are cytoplasmic, mitochondrial and chloroplastic isozymes.

219594:CDK11A
gene id: 219594:CDK11A
uniprot id: A0A6J3E224
uniprot id: A0A6J3E6S0
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.

219594:MICAL3
gene id: 219594:MICAL3
uniprot id: A0A6J3D1U2
uniprot id: A0A6J3D1Y4
uniprot id: A0A6J3D1Z5
uniprot id: A0A6J3D219
uniprot id: A0A6J3D466
uniprot id: A0A6J3D492
uniprot id: A0A6J3D4A5
uniprot id: A0A6J3D4E1
uniprot id: A0A6J3D4L7
uniprot id: A0A6J3D704
uniprot id: A0A6J3D7R5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mical family.
messages: Nucleus
messages: cytoskeleton

219594:HEPHL1
gene id: 219594:HEPHL1
uniprot id: A0A6J3EDE5
names: Similarity
messages: Belongs to the multicopper oxidase family.

219594:LOC116498293
gene id: 219594:LOC116498293
uniprot id: A0A6J3E477
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:CXXC4
gene id: 219594:CXXC4
uniprot id: A0A6J3CX79
uniprot id: A0A6J3CYC1
names: Subcellular Location Annotation
messages: Cytoplasm

219594:TMEM59L
gene id: 219594:TMEM59L
uniprot id: A0A6J3E763
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM59 family.
messages: Golgi apparatus membrane
messages: Membrane

219594:GMFB
gene id: 219594:GMFB
uniprot id: A0A6J3CYM9
names: Similarity
messages: Belongs to the actin-binding proteins ADF family. GMF subfamily.

219594:UBA52
gene id: 219594:UBA52
uniprot id: A0A6J3EBU3
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the eukaryotic ribosomal protein eL40 family.
messages: In the N-terminal section; belongs to the ubiquitin family.
messages: Nucleus

219594:EDN3
gene id: 219594:EDN3
uniprot id: A0A6J3DWA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endothelin/sarafotoxin family.
messages: Secreted

219594:ZDHHC21
gene id: 219594:ZDHHC21
uniprot id: A0A6J3ED01
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

219594:MCM10
gene id: 219594:MCM10
uniprot id: A0A6J3EQU9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCM10 family.
messages: Nucleus

219594:SBNO1
gene id: 219594:SBNO1
uniprot id: A0A6J3DZZ7
uniprot id: A0A6J3E127
names: Similarity
messages: Belongs to the SBNO family.

219594:IFT46
gene id: 219594:IFT46
uniprot id: A0A6J3E881
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IFT46 family.
messages: cilium
messages: cilium basal body

219594:RAB18
gene id: 219594:RAB18
uniprot id: A0A6J3CHJ0
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Cell membrane
messages: Lipid droplet

219594:TCF7L2
gene id: 219594:TCF7L2
uniprot id: A0A6J3D797
uniprot id: A0A6J3D7A3
uniprot id: A0A6J3D7A7
uniprot id: A0A6J3D9Y6
uniprot id: A0A6J3D9Z2
uniprot id: A0A6J3D9Z6
uniprot id: A0A6J3DAN1
uniprot id: A0A6J3DAN6
uniprot id: A0A6J3DAP2
uniprot id: A0A6J3DCT8
uniprot id: A0A6J3DCU7
uniprot id: A0A6J3DD78
uniprot id: A0A6J3DD82
uniprot id: A0A6J3DD88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCF/LEF family.
messages: Nucleus

219594:LOC116495420
gene id: 219594:LOC116495420
uniprot id: A0A6J3DQK3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the globin family.
messages: Heterotetramer of two alpha-D chains and two beta chains.
messages: Involved in oxygen transport from the lung to the various peripheral tissues.

219594:LOC116486847
gene id: 219594:LOC116486847
uniprot id: A0A6J3CMF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 23 family.
messages: Secreted

219594:ADTRP
gene id: 219594:ADTRP
uniprot id: A0A6J3CQJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIG1 family.
messages: Membrane

219594:TAF7L
gene id: 219594:TAF7L
uniprot id: A0A6J3DPZ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF7 family.
messages: Nucleus

219594:TRAM2
gene id: 219594:TRAM2
uniprot id: A0A6J3CSB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAM family.
messages: Membrane

219594:SLC8B1
gene id: 219594:SLC8B1
uniprot id: A0A6J3DUY7
names: Subcellular Location Annotation
messages: Membrane

219594:SFXN3
gene id: 219594:SFXN3
uniprot id: A0A6J3D8K5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sideroflexin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Mitochondrion membrane

219594:SVOP
gene id: 219594:SVOP
uniprot id: A0A6J3DVT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator (TC 2.A.1) superfamily. Organic cation transporter (TC 2.A.1.19) family.
messages: Belongs to the major facilitator superfamily.
messages: Membrane

219594:THADA
gene id: 219594:THADA
uniprot id: A0A6J3CMH9
names: Similarity
messages: Belongs to the THADA family.

219594:BDKRB1
gene id: 219594:BDKRB1
uniprot id: A0A6J3D3J2
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: This is a receptor for bradykinin. Could be a factor in chronic pain and inflammation.

219594:PLA2G4A
gene id: 219594:PLA2G4A
uniprot id: A0A6J3DFJ1
names: Domain
messages: The N-terminal C2 domain associates with lipid membranes upon calcium binding.

219594:PEX5
gene id: 219594:PEX5
uniprot id: A0A6J3CI26
uniprot id: A0A6J3CLP8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxisomal targeting signal receptor family.
messages: Binds to the C-terminal PTS1-type tripeptide peroxisomal targeting signal (SKL-type) and plays an essential role in peroxisomal protein import.
messages: Cytoplasm
messages: Membrane

219594:CZH18orf32
gene id: 219594:CZH18orf32
uniprot id: A0A6J3EK22
names: Similarity
messages: Belongs to the UPF0729 family.

219594:MORF4L1
gene id: 219594:MORF4L1
uniprot id: A0A6J3DGN9
uniprot id: A0A6J3DJA2
uniprot id: A0A6J3DKQ4
names: Subcellular Location Annotation
messages: Nucleus

219594:MYADML2
gene id: 219594:MYADML2
uniprot id: A0A6J3DXB2
names: Subcellular Location Annotation
messages: Membrane

219594:TLE2
gene id: 219594:TLE2
uniprot id: A0A6J3E792
uniprot id: A0A6J3ECB9
uniprot id: A0A6J3EE09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat Groucho/TLE family.
messages: Nucleus

219594:AIDA
gene id: 219594:AIDA
uniprot id: A0A6J3CLE9
uniprot id: A0A6J3CRB3
uniprot id: A0A6J3CSC1
names: Similarity
messages: Belongs to the AIDA family.

219594:LOC116500115
gene id: 219594:LOC116500115
uniprot id: A0A6J3EB56
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:NMNAT1
gene id: 219594:NMNAT1
uniprot id: A0A6J3E572
names: Similarity
messages: Belongs to the eukaryotic NMN adenylyltransferase family.

219594:CHMP1B
gene id: 219594:CHMP1B
uniprot id: A0A6J3DN75
names: Similarity
messages: Belongs to the SNF7 family.

219594:ING4
gene id: 219594:ING4
uniprot id: A0A6J3EPE9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ING family.
messages: Component of an histone acetyltransferase complex.
messages: Component of an histone acetyltransferase complex. Interacts with H3K4me3 and to a lesser extent with H3K4me2.
messages: Nucleus
messages: The PHD-type zinc finger mediates the binding to H3K4me3.

219594:FZD10
gene id: 219594:FZD10
uniprot id: A0A6J3DUH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor Fz/Smo family.
messages: Cell membrane
messages: Membrane

219594:CALB2
gene id: 219594:CALB2
uniprot id: A0A6J3DM45
names: Function
names: Similarity
messages: Belongs to the calbindin family.
messages: Calretinin is a calcium-binding protein which is abundant in auditory neurons.

219594:ACTG2
gene id: 219594:ACTG2
uniprot id: A0A6J3EA28
names: Similarity
messages: Belongs to the actin family.

219594:EXTL2
gene id: 219594:EXTL2
uniprot id: A0A6J3DA18
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane

219594:C11H15orf40
gene id: 219594:C11H15orf40
uniprot id: A0A6J3DMW0
names: Similarity
messages: Belongs to the UPF0235 family.

219594:SLC15A4
gene id: 219594:SLC15A4
uniprot id: A0A6J3DUB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Membrane

219594:LOC116488977
gene id: 219594:LOC116488977
uniprot id: A0A6J3D111
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NIP3 family.
messages: Membrane

219594:MSX1
gene id: 219594:MSX1
uniprot id: A0A6J3CYD9
names: Subcellular Location Annotation
messages: Nucleus

219594:TRIQK
gene id: 219594:TRIQK
uniprot id: A0A6J3CNP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRIQK family.
messages: Endoplasmic reticulum membrane
messages: Membrane

219594:LOC116501451
gene id: 219594:LOC116501451
uniprot id: A0A6J3ELY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:TBX18
gene id: 219594:TBX18
uniprot id: A0A6J3CV47
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

219594:LMNB2
gene id: 219594:LMNB2
uniprot id: A0A6J3E8G2
names: Similarity
messages: Belongs to the intermediate filament family.

219594:KCNK9
gene id: 219594:KCNK9
uniprot id: A0A6J3CKE7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane
messages: pH-dependent, voltage-insensitive, background potassium channel protein.

219594:LOC116489288
gene id: 219594:LOC116489288
uniprot id: A0A6J3CYU1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:TTLL1
gene id: 219594:TTLL1
uniprot id: A0A6J3D2G1
uniprot id: A0A6J3D8B4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tubulin polyglutamylase family.
messages: cilium basal body

219594:FAM189A2
gene id: 219594:FAM189A2
uniprot id: A0A6J3EFY8
names: Similarity
messages: Belongs to the ENTREP family.

219594:TBCE
gene id: 219594:TBCE
uniprot id: A0A6J3CRZ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TBCE family.
messages: Cytoplasm

219594:EPHA2
gene id: 219594:EPHA2
uniprot id: A0A6J3E1S8
names: Subcellular Location Annotation
messages: Membrane

219594:MYBBP1A
gene id: 219594:MYBBP1A
uniprot id: A0A6J3E4G5
names: Similarity
messages: Belongs to the MYBBP1A family.

219594:C2H18orf21
gene id: 219594:C2H18orf21
uniprot id: A0A6J3CIY7
names: Similarity
messages: Belongs to the UPF0711 family.

219594:FUT9
gene id: 219594:FUT9
uniprot id: A0A6J3CNE4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 10 family.
messages: Golgi stack membrane

219594:PFKL
gene id: 219594:PFKL
uniprot id: A0A6J3DFX7
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP, AMP, or fructose 2,6-bisphosphate, and allosterically inhibited by ATP or citrate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade "E" sub-subfamily.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homo- and heterotetramers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:LOC116489876
gene id: 219594:LOC116489876
uniprot id: A0A6J3D201
names: Domain
names: Subcellular Location Annotation
messages: The N-terminal C2 domain associates with lipid membranes upon calcium binding.
messages: cytosol

219594:EGF
gene id: 219594:EGF
uniprot id: A0A6J3CSB3
uniprot id: A0A6J3CUL6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:LOC116499727
gene id: 219594:LOC116499727
uniprot id: A0A6J3E9H2
names: Similarity
names: Subunit
messages: Belongs to the avian keratin family.
messages: The avian keratins (F-ker, S-ker, C-ker and B-ker) are a complex mixture of very similar polypeptides.

219594:TAFA3
gene id: 219594:TAFA3
uniprot id: A0A6J3E6B8
names: Similarity
messages: Belongs to the TAFA family.

219594:NRCAM
gene id: 219594:NRCAM
uniprot id: A0A6J3DIR0
uniprot id: A0A6J3DIU9
uniprot id: A0A6J3DIW3
uniprot id: A0A6J3DIZ6
uniprot id: A0A6J3DJ05
uniprot id: A0A6J3DJ30
uniprot id: A0A6J3DJ87
uniprot id: A0A6J3DJA1
uniprot id: A0A6J3DLB0
uniprot id: A0A6J3DLD3
uniprot id: A0A6J3DLJ6
uniprot id: A0A6J3DLN7
uniprot id: A0A6J3DLQ9
uniprot id: A0A6J3DLS4
uniprot id: A0A6J3DLU1
uniprot id: A0A6J3DMW3
uniprot id: A0A6J3DN25
uniprot id: A0A6J3DNA0
uniprot id: A0A6J3DNB0
uniprot id: A0A6J3DND5
uniprot id: A0A6J3DNI3
uniprot id: A0A6J3DP05
uniprot id: A0A6J3DP45
uniprot id: A0A6J3DP63
uniprot id: A0A6J3DP97
uniprot id: A0A6J3DPC3
uniprot id: A0A6J3DPH1
uniprot id: A0A6J3DPL2
uniprot id: A0A6J3DPT3
uniprot id: A0A6J3DQ34
uniprot id: A0A6J3DQ43
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. L1/neurofascin/NgCAM family.
messages: Membrane

219594:ATP6V0C
gene id: 219594:ATP6V0C
uniprot id: A0A6J3DRS8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the V-ATPase proteolipid subunit family.
messages: Membrane
messages: Proton-conducting pore forming of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex. The V1 complex consists of three catalytic AB heterodimers that form a heterohexamer, three peripheral stalks each consisting of EG heterodimers, one central rotor including subunits D and F, and the regulatory subunits C and H. The proton translocation complex V0 consists of the proton transport subunit a, a ring of proteolipid subunits c9c'', rotary subunit d, subunits e and f, and the accessory subunits.
messages: Vacuole membrane
messages: clathrin-coated vesicle membrane
messages: synaptic vesicle membrane

219594:VWDE
gene id: 219594:VWDE
uniprot id: A0A6J3CDJ2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:KRTCAP2
gene id: 219594:KRTCAP2
uniprot id: A0A6J3EGE7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KRTCAP2 family.
messages: Membrane

219594:SLC29A1
gene id: 219594:SLC29A1
uniprot id: A0A6J3CSZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC29A/ENT transporter (TC 2.A.57) family.
messages: Membrane

219594:LOC116486636
gene id: 219594:LOC116486636
uniprot id: A0A6J3CIX0
names: Similarity
names: Subunit
messages: Belongs to the avian keratin family.
messages: The avian keratins (F-ker, S-ker, C-ker and B-ker) are a complex mixture of very similar polypeptides.

219594:LOC116502101
gene id: 219594:LOC116502101
uniprot id: A0A6J3EKD3
names: Similarity
messages: Belongs to the Arg-specific ADP-ribosyltransferase family.

219594:SLITRK1
gene id: 219594:SLITRK1
uniprot id: A0A6J3EEY5
names: Similarity
messages: Belongs to the SLITRK family.

219594:PDE2A
gene id: 219594:PDE2A
uniprot id: A0A6J3EH44
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

219594:LOC116494475
gene id: 219594:LOC116494475
uniprot id: A0A6J3DLC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:PSMG2
gene id: 219594:PSMG2
uniprot id: A0A6J3CGP9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PSMG2 family.
messages: Chaperone protein which promotes assembly of the 20S proteasome as part of a heterodimer with PSMG1.
messages: Forms a heterodimer with PSMG1.

219594:LOC116494735
gene id: 219594:LOC116494735
uniprot id: A0A6J3DPV9
names: Similarity
messages: Belongs to the SCO1/2 family.

219594:SUGP2
gene id: 219594:SUGP2
uniprot id: A0A6J3ECG1
names: Subcellular Location Annotation
messages: Nucleus

219594:TMBIM4
gene id: 219594:TMBIM4
uniprot id: A0A6J3EIE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

219594:DGKI
gene id: 219594:DGKI
uniprot id: A0A6J3DZH3
uniprot id: A0A6J3E0H1
names: Similarity
messages: Belongs to the eukaryotic diacylglycerol kinase family.

219594:HOXB13
gene id: 219594:HOXB13
uniprot id: A0A6J3E5H7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus

219594:SLC5A6
gene id: 219594:SLC5A6
uniprot id: A0A6J3CVM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

219594:FAT1
gene id: 219594:FAT1
uniprot id: A0A6J3CT62
uniprot id: A0A6J3CVI3
uniprot id: A0A6J3CY95
uniprot id: A0A6J3CZC1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:KLC1
gene id: 219594:KLC1
uniprot id: A0A6J3D200
uniprot id: A0A6J3D6Z3
uniprot id: A0A6J3D7U0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the kinesin light chain family.
messages: Kinesin is a microtubule-associated force-producing protein that play a role in organelle transport.
messages: Oligomeric complex composed of two heavy chains and two light chains.
messages: cytoskeleton

219594:PAIP2B
gene id: 219594:PAIP2B
uniprot id: A0A6J3CZE4
names: Similarity
messages: Belongs to the PAIP2 family.

219594:HLX
gene id: 219594:HLX
uniprot id: A0A6J3CMH5
names: Subcellular Location Annotation
messages: Nucleus

219594:LOC116500392
gene id: 219594:LOC116500392
uniprot id: A0A6J3EH23
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alpha/beta interferon family.
messages: Has antiviral activities.
messages: Secreted

219594:POLR3B
gene id: 219594:POLR3B
uniprot id: A0A6J3E696
names: Function
names: Similarity
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.

219594:NUSAP1
gene id: 219594:NUSAP1
uniprot id: A0A6J3D1F1
uniprot id: A0A6J3D3X4
uniprot id: A0A6J3D4X9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NUSAP family.
messages: Cytoplasm

219594:KDM5B
gene id: 219594:KDM5B
uniprot id: A0A6J3E770
uniprot id: A0A6J3ECD8
names: Similarity
messages: Belongs to the JARID1 histone demethylase family.

219594:KCNK18
gene id: 219594:KCNK18
uniprot id: A0A6J3D7Z1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

219594:NKIRAS2
gene id: 219594:NKIRAS2
uniprot id: A0A6J3E5V1
names: Similarity
messages: Belongs to the small GTPase superfamily. Ras family. KappaB-Ras subfamily.

219594:LOC116502118
gene id: 219594:LOC116502118
uniprot id: A0A6J3EKF2
names: Similarity
messages: Belongs to the Arg-specific ADP-ribosyltransferase family.

219594:PLPP2
gene id: 219594:PLPP2
uniprot id: A0A6J3EC32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Membrane

219594:GALK2
gene id: 219594:GALK2
uniprot id: A0A6J3DGP5
uniprot id: A0A6J3DMR6
names: Similarity
messages: Belongs to the GHMP kinase family. GalK subfamily.

219594:PLA2G12A
gene id: 219594:PLA2G12A
uniprot id: A0A6J3CUX2
names: Subcellular Location Annotation
messages: Secreted

219594:SLC9A3R1
gene id: 219594:SLC9A3R1
uniprot id: A0A6J3DXV6
names: Function
names: Subcellular Location Annotation
messages: Endomembrane system
messages: Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression.
messages: filopodium
messages: microvillus
messages: ruffle

219594:LOC116496416
gene id: 219594:LOC116496416
uniprot id: A0A6J3DVI2
uniprot id: A0A6J3DXD4
uniprot id: A0A6J3DZP0
uniprot id: A0A6J3E0G5
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

219594:MFSD4B
gene id: 219594:MFSD4B
uniprot id: A0A6J3CTR2
names: Subcellular Location Annotation
messages: Membrane

219594:ITGA8
gene id: 219594:ITGA8
uniprot id: A0A6J3CR40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

219594:CDK8
gene id: 219594:CDK8
uniprot id: A0A6J3E4Z4
uniprot id: A0A6J3EA03
uniprot id: A0A6J3EA13
names: Similarity
messages: Belongs to the protein kinase superfamily.

219594:GRHL2
gene id: 219594:GRHL2
uniprot id: A0A6J3CJQ4
names: Subcellular Location Annotation
messages: Nucleus

219594:LOC116495768
gene id: 219594:LOC116495768
uniprot id: A0A6J3DSF4
names: Similarity
messages: Belongs to the perilipin family.

219594:BLOC1S6
gene id: 219594:BLOC1S6
uniprot id: A0A6J3DKL2
names: Function
names: Similarity
messages: Belongs to the BLOC1S6 family.
messages: Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. May play a role in intracellular vesicle trafficking, particularly in the vesicle-docking and fusion process.

219594:IPMK
gene id: 219594:IPMK
uniprot id: A0A6J3DCF6
names: Similarity
messages: Belongs to the inositol phosphokinase (IPK) family.

219594:GOLPH3
gene id: 219594:GOLPH3
uniprot id: A0A6J3EE10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GOLPH3/VPS74 family.
messages: Golgi stack membrane
messages: Membrane
messages: trans-Golgi network membrane

219594:SGPL1
gene id: 219594:SGPL1
uniprot id: A0A6J3DC91
names: Similarity
messages: Belongs to the group II decarboxylase family.

219594:LOC116489614
gene id: 219594:LOC116489614
uniprot id: A0A6J3D0L1
names: Subcellular Location Annotation
messages: Membrane

219594:ATXN3
gene id: 219594:ATXN3
uniprot id: A0A6J3CYP9
uniprot id: A0A6J3D1A3
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

219594:DZIP1
gene id: 219594:DZIP1
uniprot id: A0A6J3EC86
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DZIP C2H2-type zinc-finger protein family.
messages: centriole
messages: cilium basal body

219594:OSTC
gene id: 219594:OSTC
uniprot id: A0A6J3CYS4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OSTC family.
messages: Component of the oligosaccharyltransferase (OST) complex.
messages: Membrane
messages: Specific component of the STT3A-containing form of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity.

219594:LASP1
gene id: 219594:LASP1
uniprot id: A0A6J3E506
uniprot id: A0A6J3E9F3
names: Function
names: Subcellular Location Annotation
messages: Plays an important role in the regulation of dynamic actin-based, cytoskeletal activities. Agonist-dependent changes in LASP1 phosphorylation may also serve to regulate actin-associated ion transport activities, not only in the parietal cell but also in certain other F-actin-rich secretory epithelial cell types.
messages: cell cortex
messages: cytoskeleton

219594:LOC116501422
gene id: 219594:LOC116501422
uniprot id: A0A6J3EI36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

219594:ABHD12
gene id: 219594:ABHD12
uniprot id: A0A6J3CRQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the serine esterase family.
messages: Endoplasmic reticulum membrane
messages: Membrane

219594:TTC25
gene id: 219594:TTC25
uniprot id: A0A6J3E8I3
names: Subcellular Location Annotation
messages: cilium axoneme

219594:OAF
gene id: 219594:OAF
uniprot id: A0A6J3E3T3
names: Similarity
messages: Belongs to the OAF family.

219594:CRY2
gene id: 219594:CRY2
uniprot id: A0A6J3CYN4
uniprot id: A0A6J3D186
names: Similarity
messages: Belongs to the DNA photolyase class-1 family.

219594:BNIP1
gene id: 219594:BNIP1
uniprot id: A0A6J3DNT6
names: Subcellular Location Annotation
messages: Membrane

219594:DIPK1C
gene id: 219594:DIPK1C
uniprot id: A0A6J3CKI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DIPK family.
messages: Endoplasmic reticulum membrane

219594:CPT1A
gene id: 219594:CPT1A
uniprot id: A0A6J3D396
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the carnitine/choline acetyltransferase family.
messages: Membrane
messages: Mitochondrion outer membrane

219594:GPX1
gene id: 219594:GPX1
uniprot id: A0A6J3DH84
uniprot id: A0A6J3DIH7
names: Similarity
messages: Belongs to the glutathione peroxidase family.

219594:CCNT1
gene id: 219594:CCNT1
uniprot id: A0A6J3EBU1
names: Similarity
messages: Belongs to the cyclin family. Cyclin C subfamily.

219594:PAM16
gene id: 219594:PAM16
uniprot id: A0A6J3DPQ4
names: Similarity
messages: Belongs to the TIM16/PAM16 family.

219594:CHST2
gene id: 219594:CHST2
uniprot id: A0A6J3DID7
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

219594:GDF9
gene id: 219594:GDF9
uniprot id: A0A6J3DS73
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TGF-beta family.
messages: Homodimer or heterodimer (Potential). But, in contrast to other members of this family, cannot be disulfide-linked.
messages: Secreted

219594:ATP2B1
gene id: 219594:ATP2B1
uniprot id: A0A6J3D1L7
uniprot id: A0A6J3D3Z8
uniprot id: A0A6J3D524
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIB subfamily.
messages: Catalyzes the hydrolysis of ATP coupled with the transport of calcium.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

219594:CLASP1
gene id: 219594:CLASP1
uniprot id: A0A6J3D508
uniprot id: A0A6J3D513
uniprot id: A0A6J3D518
uniprot id: A0A6J3D7Q0
uniprot id: A0A6J3D7Q5
uniprot id: A0A6J3D7R0
uniprot id: A0A6J3D7R4
uniprot id: A0A6J3D874
uniprot id: A0A6J3D879
uniprot id: A0A6J3D884
uniprot id: A0A6J3DAE5
uniprot id: A0A6J3DAF0
uniprot id: A0A6J3DAX4
uniprot id: A0A6J3DAX9
uniprot id: A0A6J3DAY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CLASP family.
messages: centrosome
messages: kinetochore
messages: trans-Golgi network

219594:CTBS
gene id: 219594:CTBS
uniprot id: A0A6J3D9D4
uniprot id: A0A6J3DF42
uniprot id: A0A6J3DF85
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family.

219594:LOC116497301
gene id: 219594:LOC116497301
uniprot id: A0A6J3E4X0
names: Similarity
messages: Belongs to the flavin monoamine oxidase family.

219594:CDH15
gene id: 219594:CDH15
uniprot id: A0A6J3DQU9
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane
messages: Membrane

219594:PARVA
gene id: 219594:PARVA
uniprot id: A0A6J3CZ39
uniprot id: A0A6J3CZE2
uniprot id: A0A6J3D1N6
uniprot id: A0A6J3D2S6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the parvin family.
messages: cytoskeleton

219594:DST
gene id: 219594:DST
uniprot id: A0A6J3CLH8
uniprot id: A0A6J3CLI3
uniprot id: A0A6J3CLI8
uniprot id: A0A6J3CN54
uniprot id: A0A6J3CN59
uniprot id: A0A6J3CN65
uniprot id: A0A6J3CP53
uniprot id: A0A6J3CP58
uniprot id: A0A6J3CRD9
uniprot id: A0A6J3CRE7
uniprot id: A0A6J3CSF5
uniprot id: A0A6J3CSF9
uniprot id: A0A6J3CSG5
names: Subcellular Location Annotation
messages: cytoskeleton

219594:ARHGEF2
gene id: 219594:ARHGEF2
uniprot id: A0A6J3EA35
uniprot id: A0A6J3EEU3
uniprot id: A0A6J3EF57
uniprot id: A0A6J3EGV9
names: Subcellular Location Annotation
messages: Cytoplasmic vesicle
messages: Golgi apparatus
messages: Vesicle
messages: spindle
messages: tight junction

219594:PPA1
gene id: 219594:PPA1
uniprot id: A0A6J3DE20
names: Similarity
messages: Belongs to the PPase family.

219594:CRYBB2
gene id: 219594:CRYBB2
uniprot id: A0A6J3DUS7
uniprot id: A0A6J3DYV9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the beta/gamma-crystallin family.
messages: Crystallins are the dominant structural components of the vertebrate eye lens.
messages: Homo/heterodimer, or complexes of higher-order. The structure of beta-crystallin oligomers seems to be stabilized through interactions between the N-terminal arms.

219594:MVB12A
gene id: 219594:MVB12A
uniprot id: A0A6J3EHR9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MVB12 family.
messages: Endosome membrane
messages: Late endosome membrane
messages: Membrane

219594:PTDSS1
gene id: 219594:PTDSS1
uniprot id: A0A6J3CFR9
uniprot id: A0A6J3CGQ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphatidyl serine synthase family.
messages: Catalyzes a base-exchange reaction in which the polar head group of phosphatidylethanolamine (PE) is replaced by L-serine.
messages: Endoplasmic reticulum membrane
messages: Membrane

219594:SQSTM1
gene id: 219594:SQSTM1
uniprot id: A0A6J3DTT8
uniprot id: A0A6J3DUP5
names: Subcellular Location Annotation
messages: autophagosome

219594:STC2
gene id: 219594:STC2
uniprot id: A0A6J3DUX4
names: Similarity
names: Subunit
messages: Belongs to the stanniocalcin family.
messages: Homodimer; disulfide-linked.

219594:HAO1
gene id: 219594:HAO1
uniprot id: A0A6J3CX36
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

219594:PGM1
gene id: 219594:PGM1
uniprot id: A0A6J3DGE1
names: Similarity
messages: Belongs to the phosphohexose mutase family.

219594:HDX
gene id: 219594:HDX
uniprot id: A0A6J3DKS5
uniprot id: A0A6J3DN83
uniprot id: A0A6J3DQ13
names: Subcellular Location Annotation
messages: Nucleus

219594:CAPN5
gene id: 219594:CAPN5
uniprot id: A0A6J3DKH5
names: Similarity
messages: Belongs to the peptidase C2 family.

219594:LOC116494508
gene id: 219594:LOC116494508
uniprot id: A0A6J3DLG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NIPA family.
messages: Membrane

219594:MUC2
gene id: 219594:MUC2
uniprot id: A0A6J3D082
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:LOC116485674
gene id: 219594:LOC116485674
uniprot id: A0A6J3CF52
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

219594:LOC116500759
gene id: 219594:LOC116500759
uniprot id: A0A6J3EJ21
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the APH-1 family.
messages: Component of the gamma-secretase complex.
messages: Membrane
messages: Potential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral proteins such as Notch receptors.

219594:SAP30
gene id: 219594:SAP30
uniprot id: A0A6J3CYC2
names: Similarity
messages: Belongs to the SAP30 family.

219594:MSX2
gene id: 219594:MSX2
uniprot id: A0A6J3DUN2
names: Subcellular Location Annotation
messages: Nucleus

219594:ZIC5
gene id: 219594:ZIC5
uniprot id: A0A6J3E5T0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GLI C2H2-type zinc-finger protein family.
messages: Nucleus

219594:SEC23A
gene id: 219594:SEC23A
uniprot id: A0A6J3D4S7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEC23/SEC24 family. SEC23 subfamily.
messages: COPII-coated vesicle membrane
messages: Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: cytosol

219594:TAF15
gene id: 219594:TAF15
uniprot id: A0A6J3E4G0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM TET family.
messages: Nucleus

219594:GABARAPL1
gene id: 219594:GABARAPL1
uniprot id: A0A6J3D0Z0
names: Similarity
messages: Belongs to the ATG8 family.

219594:ATP6AP1L
gene id: 219594:ATP6AP1L
uniprot id: A0A6J3ELH5
names: Similarity
messages: Belongs to the vacuolar ATPase subunit S1 family.

219594:LOC116492697
gene id: 219594:LOC116492697
uniprot id: A0A6J3DH76
names: Similarity
messages: Belongs to the DNA photolyase class-2 family.

219594:PCNX1
gene id: 219594:PCNX1
uniprot id: A0A6J3D0X1
uniprot id: A0A6J3D399
uniprot id: A0A6J3D3J9
uniprot id: A0A6J3D5U6
uniprot id: A0A6J3D5V1
uniprot id: A0A6J3D6Q8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pecanex family.
messages: Membrane

219594:LOC116489191
gene id: 219594:LOC116489191
uniprot id: A0A6J3CYQ8
names: Similarity
messages: Belongs to the TFIIE alpha subunit family.

219594:IL10
gene id: 219594:IL10
uniprot id: A0A6J3EBH9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-10 family.
messages: Immune regulatory cytokine.
messages: Secreted

219594:LOC116488473
gene id: 219594:LOC116488473
uniprot id: A0A6J3CUX8
names: Subcellular Location Annotation
messages: Nucleus

219594:LOC116497513
gene id: 219594:LOC116497513
uniprot id: A0A6J3E244
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

219594:TUBB4B
gene id: 219594:TUBB4B
uniprot id: A0A6J3E2L8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
messages: cytoskeleton

219594:SLC23A2
gene id: 219594:SLC23A2
uniprot id: A0A6J3EAA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

219594:MBOAT4
gene id: 219594:MBOAT4
uniprot id: A0A6J3CS49
names: Subcellular Location Annotation
messages: Membrane

219594:LOC116497196
gene id: 219594:LOC116497196
uniprot id: A0A6J3E3K3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family.
messages: Membrane

219594:RHBDF2
gene id: 219594:RHBDF2
uniprot id: A0A6J3DW16
uniprot id: A0A6J3E083
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S54 family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Regulates ADAM17 protease, a sheddase of the epidermal growth factor (EGF) receptor ligands and TNF, thereby plays a role in sleep, cell survival, proliferation, migration and inflammation. Does not exhibit any protease activity on its own.

219594:RAD23B
gene id: 219594:RAD23B
uniprot id: A0A6J3ED39
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RAD23 family.
messages: Cytoplasm
messages: Multiubiquitin chain receptor involved in modulation of proteasomal degradation. Involved in nucleotide excision repair.
messages: Nucleus

219594:SYPL2
gene id: 219594:SYPL2
uniprot id: A0A6J3EAM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptophysin/synaptobrevin family.
messages: Membrane

219594:PODXL
gene id: 219594:PODXL
uniprot id: A0A6J3EIN2
uniprot id: A0A6J3EJY4
uniprot id: A0A6J3ENU5
uniprot id: A0A6J3ENV9
uniprot id: A0A6J3EQB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the podocalyxin family.
messages: Cell membrane
messages: Membrane
messages: Membrane raft
messages: filopodium
messages: lamellipodium
messages: microvillus
messages: ruffle

219594:MAB21L2
gene id: 219594:MAB21L2
uniprot id: A0A6J3D255
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mab-21 family.
messages: Cytoplasm
messages: Nucleus

219594:HSD17B3
gene id: 219594:HSD17B3
uniprot id: A0A6J3EGK4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

219594:PPL
gene id: 219594:PPL
uniprot id: A0A6J3DT24
names: Subcellular Location Annotation
messages: cytoskeleton

219594:LOC116489111
gene id: 219594:LOC116489111
uniprot id: A0A6J3CY90
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Functions as a GTPase-activating protein for the small GTPases RHOA, RHOB, RHOC and CDC42, terminating their downstream signaling. This induces morphological changes and detachment through cytoskeletal reorganization, playing a critical role in biological processes such as cell migration and proliferation. Also functions in vivo as an activator of the phospholipase PLCD1. Active DLC1 increases cell migration velocity but reduces directionality.
messages: Interacts with EF1A1, facilitates EF1A1 distribution to the membrane periphery and ruffles upon growth factor stimulation and suppresses cell migration.
messages: Membrane
messages: focal adhesion

219594:RNASEH1
gene id: 219594:RNASEH1
uniprot id: A0A6J3CPV5
uniprot id: A0A6J3CVZ3
names: Function
names: Similarity
messages: Belongs to the RNase H family.
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.

219594:ITGA9
gene id: 219594:ITGA9
uniprot id: A0A6J3CCQ9
uniprot id: A0A6J3CIZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

219594:DRC1
gene id: 219594:DRC1
uniprot id: A0A6J3CU20
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DRC1 family.
messages: Component of the nexin-dynein regulatory complex (N-DRC).
messages: cilium axoneme
messages: flagellum axoneme

219594:ITGAV
gene id: 219594:ITGAV
uniprot id: A0A6J3D5X8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

219594:PDCD10
gene id: 219594:PDCD10
uniprot id: A0A6J3DFE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PDCD10 family.
messages: Cell membrane
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Membrane

219594:KCNE1
gene id: 219594:KCNE1
uniprot id: A0A6J3CQT7
names: Similarity
messages: Belongs to the potassium channel KCNE family.

219594:FGF19
gene id: 219594:FGF19
uniprot id: A0A6J3D094
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

219594:SLC40A1
gene id: 219594:SLC40A1
uniprot id: A0A6J3DA34
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferroportin (FP) (TC 2.A.100) family. SLC40A subfamily.
messages: May be involved in iron transport and iron homeostasis.
messages: Membrane

219594:LOC116486463
gene id: 219594:LOC116486463
uniprot id: A0A6J3CP33
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

219594:LOC116487752
gene id: 219594:LOC116487752
uniprot id: A0A6J3CRQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

219594:RBM5
gene id: 219594:RBM5
uniprot id: A0A6J3DDX4
uniprot id: A0A6J3DHW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RBM5/RBM10 family.
messages: Nucleus

219594:ST3GAL4
gene id: 219594:ST3GAL4
uniprot id: A0A6J3E2B3
uniprot id: A0A6J3E3Q1
uniprot id: A0A6J3E6L0
uniprot id: A0A6J3E7B0
uniprot id: A0A6J3E8L8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

219594:SCRN3
gene id: 219594:SCRN3
uniprot id: A0A6J3D6Z6
names: Similarity
messages: Belongs to the peptidase C69 family. Secernin subfamily.

219594:SLC66A2
gene id: 219594:SLC66A2
uniprot id: A0A6J3CGK9
uniprot id: A0A6J3CL51
names: Subcellular Location Annotation
messages: Membrane

219594:DES
gene id: 219594:DES
uniprot id: A0A6J3DAK4
names: Similarity
messages: Belongs to the intermediate filament family.

219594:TJAP1
gene id: 219594:TJAP1
uniprot id: A0A6J3CWP6
uniprot id: A0A6J3CWQ2
names: Subcellular Location Annotation
messages: Membrane

219594:CANT1
gene id: 219594:CANT1
uniprot id: A0A6J3DW25
names: Similarity
messages: Belongs to the apyrase family.

219594:LOC116488942
gene id: 219594:LOC116488942
uniprot id: A0A6J3D0W5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the shootin family.
messages: axon
messages: cytoskeleton
messages: filopodium
messages: lamellipodium

219594:LOC116489570
gene id: 219594:LOC116489570
uniprot id: A0A6J3D0C8
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

219594:USP49
gene id: 219594:USP49
uniprot id: A0A6J3E7Z4
names: Similarity
messages: Belongs to the peptidase C19 family.

219594:SLC16A4
gene id: 219594:SLC16A4
uniprot id: A0A6J3E714
names: Subcellular Location Annotation
messages: Membrane

219594:TLE3
gene id: 219594:TLE3
uniprot id: A0A6J3DHY1
uniprot id: A0A6J3DKI7
uniprot id: A0A6J3DM25
uniprot id: A0A6J3DNF3
uniprot id: A0A6J3DNF8
uniprot id: A0A6J3DP25
uniprot id: A0A6J3DP27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat Groucho/TLE family.
messages: Nucleus

219594:KREMEN1
gene id: 219594:KREMEN1
uniprot id: A0A6J3DT77
uniprot id: A0A6J3DV63
uniprot id: A0A6J3DY67
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Receptor for Dickkopf proteins. Cooperates with DKK1/2 to inhibit Wnt/beta-catenin signaling by promoting the endocytosis of Wnt receptors LRP5 and LRP6.

219594:NGF
gene id: 219594:NGF
uniprot id: A0A6J3E5N2
uniprot id: A0A6J3EA46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NGF-beta family.
messages: Secreted

219594:UPP1
gene id: 219594:UPP1
uniprot id: A0A6J3CJE4
uniprot id: A0A6J3CKL2
names: Function
names: Similarity
messages: Belongs to the PNP/UDP phosphorylase family.
messages: Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis.

219594:CAMK1G
gene id: 219594:CAMK1G
uniprot id: A0A6J3E850
names: Similarity
messages: Belongs to the protein kinase superfamily.

219594:FST
gene id: 219594:FST
uniprot id: A0A6J3EDF8
uniprot id: A0A6J3EIA2
uniprot id: A0A6J3EIL7
names: Subcellular Location Annotation
messages: Secreted

219594:CCN5
gene id: 219594:CCN5
uniprot id: A0A6J3DXL1
names: Similarity
messages: Belongs to the CCN family.

219594:PIGV
gene id: 219594:PIGV
uniprot id: A0A6J3E3J8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGV family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis.
messages: Membrane

219594:LOC116494417
gene id: 219594:LOC116494417
uniprot id: A0A6J3DNI7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the archaeal Rpo11/eukaryotic RPB11/RPC19 RNA polymerase subunit family.
messages: Component of the RNA polymerase I (Pol I) and RNA polymerase III (Pol III) complexes consisting of at least 13 and 17 subunits, respectively.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common core component of RNA polymerases I and III which synthesize ribosomal RNA precursors and small RNAs, such as 5S rRNA and tRNAs, respectively.

219594:PSMB4
gene id: 219594:PSMB4
uniprot id: A0A6J3EEQ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase T1B family.
messages: Cytoplasm
messages: Non-catalytic component of the proteasome.
messages: Nucleus

219594:CAPRIN1
gene id: 219594:CAPRIN1
uniprot id: A0A6J3D1V7
uniprot id: A0A6J3D4M2
uniprot id: A0A6J3D7P3
names: Similarity
messages: Belongs to the caprin family.

219594:PTPRU
gene id: 219594:PTPRU
uniprot id: A0A6J3E4Y3
uniprot id: A0A6J3E7U8
uniprot id: A0A6J3E9Y0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Receptor class 2B subfamily.
messages: Membrane

219594:C6
gene id: 219594:C6
uniprot id: A0A6J3EF43
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complement C6/C7/C8/C9 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

219594:C17H12orf43
gene id: 219594:C17H12orf43
uniprot id: A0A6J3DYJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CUSTOS family.
messages: Nucleus envelope

219594:GDA
gene id: 219594:GDA
uniprot id: A0A6J3EH07
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia.

219594:CPNE2
gene id: 219594:CPNE2
uniprot id: A0A6J3DP77
names: Similarity
messages: Belongs to the copine family.

219594:FAM167B
gene id: 219594:FAM167B
uniprot id: A0A6J3E904
names: Similarity
messages: Belongs to the FAM167 (SEC) family.

219594:LOC116501372
gene id: 219594:LOC116501372
uniprot id: A0A6J3ELJ8
names: Similarity
messages: Belongs to the NAC-beta family.

219594:LDB1
gene id: 219594:LDB1
uniprot id: A0A6J3DB94
uniprot id: A0A6J3DBR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LDB family.
messages: Nucleus

219594:ANAPC4
gene id: 219594:ANAPC4
uniprot id: A0A6J3CYD4
names: Function
names: Similarity
messages: Belongs to the APC4 family.
messages: Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle.

219594:PDE3B
gene id: 219594:PDE3B
uniprot id: A0A6J3D220
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

219594:TMEM30A
gene id: 219594:TMEM30A
uniprot id: A0A6J3CK79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDC50/LEM3 family.
messages: Cell membrane
messages: Golgi apparatus
messages: Membrane
messages: secretory vesicle membrane

219594:GAB2
gene id: 219594:GAB2
uniprot id: A0A6J3CPD7
uniprot id: A0A6J3CS25
names: Similarity
messages: Belongs to the GAB family.

219594:EIF3I
gene id: 219594:EIF3I
uniprot id: A0A6J3E8R5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit I family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
messages: Cytoplasm

219594:LOC116491328
gene id: 219594:LOC116491328
uniprot id: A0A6J3D6P6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COX15/CtaA family.
messages: Membrane

219594:LOC116497043
gene id: 219594:LOC116497043
uniprot id: A0A6J3E2R8
names: Similarity
messages: Belongs to the calycin superfamily. Lipocalin family.

219594:LMX1B
gene id: 219594:LMX1B
uniprot id: A0A6J3E409
names: Subcellular Location Annotation
messages: Nucleus

219594:GABRG2
gene id: 219594:GABRG2
uniprot id: A0A6J3DSP0
uniprot id: A0A6J3DTT0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family. Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily. GABRG2 sub-subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

219594:VPS53
gene id: 219594:VPS53
uniprot id: A0A6J3E0Y1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS53 family.
messages: Endosome membrane
messages: Membrane
messages: trans-Golgi network membrane

219594:BARHL1
gene id: 219594:BARHL1
uniprot id: A0A6J3E2W8
names: Subcellular Location Annotation
messages: Nucleus

219594:PDXK
gene id: 219594:PDXK
uniprot id: A0A6J3CHI3
uniprot id: A0A6J3CIK0
names: Similarity
messages: Belongs to the pyridoxine kinase family.

219594:RPL8
gene id: 219594:RPL8
uniprot id: A0A6J3CRN8
names: Similarity
messages: Belongs to the universal ribosomal protein uL2 family.

219594:KIF1A
gene id: 219594:KIF1A
uniprot id: A0A6J3DDE8
uniprot id: A0A6J3DDF3
uniprot id: A0A6J3DDF8
uniprot id: A0A6J3DDG9
uniprot id: A0A6J3DG52
uniprot id: A0A6J3DG56
uniprot id: A0A6J3DG60
uniprot id: A0A6J3DG65
uniprot id: A0A6J3DHC2
uniprot id: A0A6J3DHD3
uniprot id: A0A6J3DHE0
uniprot id: A0A6J3DHE5
uniprot id: A0A6J3DIY9
uniprot id: A0A6J3DIZ5
uniprot id: A0A6J3DJ00
uniprot id: A0A6J3DJ06
uniprot id: A0A6J3DJI7
uniprot id: A0A6J3DJJ2
uniprot id: A0A6J3DJJ8
uniprot id: A0A6J3DJK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
messages: axon

219594:TCTEX1D1
gene id: 219594:TCTEX1D1
uniprot id: A0A6J3DF91
names: Similarity
messages: Belongs to the dynein light chain Tctex-type family.

219594:EPHB6
gene id: 219594:EPHB6
uniprot id: A0A6J3EJS1
uniprot id: A0A6J3EJT3
names: Subcellular Location Annotation
messages: Membrane

219594:SMPDL3B
gene id: 219594:SMPDL3B
uniprot id: A0A6J3E5D7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acid sphingomyelinase family.
messages: Binds 2 Zn(2+) per subunit.
messages: Secreted

219594:LOC116501328
gene id: 219594:LOC116501328
uniprot id: A0A6J3EG78
names: Subcellular Location Annotation
messages: Membrane

219594:NDUFA10
gene id: 219594:NDUFA10
uniprot id: A0A6J3D7F9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFA10 subunit family.
messages: Complex I is composed of 45 different subunits. This a component of the hydrophobic protein fraction.
messages: Mitochondrion matrix

219594:KCNV2
gene id: 219594:KCNV2
uniprot id: A0A6J3ECS1
names: Subcellular Location Annotation
messages: Membrane

219594:HACL1
gene id: 219594:HACL1
uniprot id: A0A6J3CI83
names: Similarity
messages: Belongs to the TPP enzyme family.

219594:DHODH
gene id: 219594:DHODH
uniprot id: A0A6J3DMI4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor. Required for UMP biosynthesis via de novo pathway.
messages: Mitochondrion inner membrane

219594:GAPDH
gene id: 219594:GAPDH
uniprot id: A0A6J3ECE8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
messages: Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively. Glyceraldehyde-3-phosphate dehydrogenase is a key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate (By similarity). Participates in nuclear events including transcription, RNA transport, DNA replication and apoptosis. Nuclear functions are probably due to the nitrosylase activity that mediates cysteine S-nitrosylation of nuclear target proteins such as SIRT1, HDAC2 and PRKDC.
messages: Homotetramer.
messages: cytosol

219594:COL4A6
gene id: 219594:COL4A6
uniprot id: A0A6J3DNG8
uniprot id: A0A6J3DQA5
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a 'chicken-wire' meshwork together with laminins, proteoglycans and entactin/nidogen.
messages: basement membrane

219594:OGDH
gene id: 219594:OGDH
uniprot id: A0A6J3EDI7
names: Similarity
messages: Belongs to the alpha-ketoglutarate dehydrogenase family.

219594:GRIA1
gene id: 219594:GRIA1
uniprot id: A0A6J3DND1
uniprot id: A0A6J3DQP6
uniprot id: A0A6J3DSQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

219594:NR5A1
gene id: 219594:NR5A1
uniprot id: A0A6J3DZU1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR5 subfamily.
messages: Nucleus

219594:LRRC14
gene id: 219594:LRRC14
uniprot id: A0A6J3CJU9
names: Subcellular Location Annotation
messages: Cytoplasm

219594:TRIM67
gene id: 219594:TRIM67
uniprot id: A0A6J3CNI8
uniprot id: A0A6J3CQH8
uniprot id: A0A6J3CTH3
uniprot id: A0A6J3CUM3
names: Subcellular Location Annotation
messages: cytoskeleton

219594:CMTM8
gene id: 219594:CMTM8
uniprot id: A0A6J3CET0
names: Subcellular Location Annotation
messages: Membrane