2184053:DN051 RS15750
gene id: 2184053:DN051_RS15750
uniprot id: A0A2Z4IYI9
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAL/histidase family.
messages: Contains an active site 4-methylidene-imidazol-5-one (MIO), which is formed autocatalytically by cyclization and dehydration of residues Cys-Ser-Gly.
messages: Cytoplasm

2184053:DN051 RS31680
gene id: 2184053:DN051_RS31680
uniprot id: A0A2Z4J6Q9
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

2184053:DN051 RS31115
gene id: 2184053:DN051_RS31115
uniprot id: A0A2Z4J687
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glutaminase PdxT/SNO family.
messages: Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.
messages: In the presence of PdxS, forms a dodecamer of heterodimers. Only shows activity in the heterodimer.

2184053:DN051 RS28775
gene id: 2184053:DN051_RS28775
uniprot id: A0A2Z4J554
names: Function
names: Similarity
messages: Belongs to the WhiA family.
messages: Involved in cell division and chromosome segregation.

2184053:DN051 RS35030
gene id: 2184053:DN051_RS35030
uniprot id: A0A2Z4J7Y2
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

2184053:DN051 RS12285
gene id: 2184053:DN051_RS12285
uniprot id: A0A2Z4IW53
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

2184053:DN051 RS34795
gene id: 2184053:DN051_RS34795
uniprot id: A0A2Z4J7M0
names: Similarity
names: Subunit
messages: Belongs to the aminoglycoside phosphotransferase family.
messages: Monomer.

2184053:DN051 RS08575
gene id: 2184053:DN051_RS08575
uniprot id: A0A2Z4IV44
names: Subcellular Location Annotation
messages: Membrane

2184053:DN051 RS22940
gene id: 2184053:DN051_RS22940
uniprot id: A0A2Z4J2D4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

2184053:DN051 RS08675
gene id: 2184053:DN051_RS08675
uniprot id: A0A2Z4IVQ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endonuclease V family.
messages: Cytoplasm
messages: DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA.

2184053:DN051 RS19565
gene id: 2184053:DN051_RS19565
uniprot id: A0A2Z4J0T4
names: Subcellular Location Annotation
messages: Membrane

2184053:DN051 RS18285
gene id: 2184053:DN051_RS18285
uniprot id: A0A2Z4J080
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
messages: Part of the 50S ribosomal subunit.

2184053:DN051 RS16870
gene id: 2184053:DN051_RS16870
uniprot id: A0A2Z4IZ78
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

2184053:DN051 RS43680
gene id: 2184053:DN051_RS43680
uniprot id: A0A2Z4JEG3
names: Similarity
messages: Belongs to the OsmC/Ohr family.

2184053:DN051 RS13880
gene id: 2184053:DN051_RS13880
uniprot id: A0A2Z4IXS5
names: Subcellular Location Annotation
messages: Membrane

2184053:DN051 RS43530
gene id: 2184053:DN051_RS43530
uniprot id: A0A2Z4JES3
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

2184053:DN051 RS25390
gene id: 2184053:DN051_RS25390
uniprot id: A0A2Z4J5H8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

2184053:DN051 RS33140
gene id: 2184053:DN051_RS33140
uniprot id: A0A2Z4J6S0
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

2184053:DN051 RS14345
gene id: 2184053:DN051_RS14345
uniprot id: A0A2Z4IYM1
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

2184053:DN051 RS27425
gene id: 2184053:DN051_RS27425
uniprot id: A0A2Z4J4K7
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

2184053:DN051 RS16725
gene id: 2184053:DN051_RS16725
uniprot id: A0A2Z4J0V5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

2184053:DN051 RS26650
gene id: 2184053:DN051_RS26650
uniprot id: A0A2Z4J488
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

2184053:DN051 RS09290
gene id: 2184053:DN051_RS09290
uniprot id: A0A2Z4IVG8
names: Similarity
messages: Belongs to the ketopantoate reductase family.

2184053:DN051 RS22935
gene id: 2184053:DN051_RS22935
uniprot id: A0A2Z4J1Z9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

2184053:DN051 RS32970
gene id: 2184053:DN051_RS32970
uniprot id: A0A2Z4J7B6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CobB/CobQ family. GatD subfamily.
messages: Forms a heterodimer with MurT.
messages: The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The GatD subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia. The resulting ammonia molecule is channeled to the active site of MurT.

2184053:DN051 RS32785
gene id: 2184053:DN051_RS32785
uniprot id: A0A2Z4J8Y4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

2184053:DN051 RS16115
gene id: 2184053:DN051_RS16115
uniprot id: A0A2Z4IYW9
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.

2184053:DN051 RS30490
gene id: 2184053:DN051_RS30490
uniprot id: A0A2Z4J5I2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

2184053:DN051 RS16490
gene id: 2184053:DN051_RS16490
uniprot id: A0A2Z4IYV7
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

2184053:DN051 RS16750
gene id: 2184053:DN051_RS16750
uniprot id: A0A2Z4IZT2
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

2184053:DN051 RS31415
gene id: 2184053:DN051_RS31415
uniprot id: A0A2Z4J7H4
names: Similarity
messages: Belongs to the glycosyl hydrolase family 6.

2184053:DN051 RS09240
gene id: 2184053:DN051_RS09240
uniprot id: A0A2Z4IVF6
names: Subcellular Location Annotation
messages: Membrane

2184053:DN051 RS31445
gene id: 2184053:DN051_RS31445
uniprot id: A0A2Z4J693
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family.
messages: Membrane

2184053:DN051 RS20970
gene id: 2184053:DN051_RS20970
uniprot id: A0A2Z4J0R7
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

2184053:DN051 RS28750
gene id: 2184053:DN051_RS28750
uniprot id: A0A2Z4J4Z5
names: Function
names: Subcellular Location Annotation
messages: Iron-sulfur subunit of the cytochrome bc1 complex, an essential component of the respiratory electron transport chain required for ATP synthesis. The bc1 complex catalyzes the oxidation of menaquinol and the reduction of cytochrome c in the respiratory chain. The bc1 complex operates through a Q-cycle mechanism that couples electron transfer to generation of the proton gradient that drives ATP synthesis.
messages: Membrane

2184053:DN051 RS26425
gene id: 2184053:DN051_RS26425
uniprot id: A0A2Z4J4D4
names: Similarity
messages: Belongs to the OsmC/Ohr family.

2184053:DN051 RS29675
gene id: 2184053:DN051_RS29675
uniprot id: A0A2Z4J5N7
names: Similarity
messages: Belongs to the TlyA family.

2184053:DN051 RS32555
gene id: 2184053:DN051_RS32555
uniprot id: A0A2Z4J6S1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

2184053:DN051 RS29310
gene id: 2184053:DN051_RS29310
uniprot id: A0A2Z4J599
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane

2184053:DN051 RS32075
gene id: 2184053:DN051_RS32075
uniprot id: A0A2Z4J6K8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2184053:DN051 RS29880
gene id: 2184053:DN051_RS29880
uniprot id: A0A2Z4J7J4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SepF family.
messages: Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
messages: Cytoplasm
messages: Homodimer. Interacts with FtsZ.

2184053:DN051 RS22390
gene id: 2184053:DN051_RS22390
uniprot id: A0A2Z4J3Q2
names: Subcellular Location Annotation
messages: Membrane

2184053:DN051 RS28930
gene id: 2184053:DN051_RS28930
uniprot id: A0A2Z4J5H2
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

2184053:DN051 RS16760
gene id: 2184053:DN051_RS16760
uniprot id: A0A2Z4IZ60
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

2184053:DN051 RS13065
gene id: 2184053:DN051_RS13065
uniprot id: A0A2Z4IX64
names: Subcellular Location Annotation
messages: Membrane

2184053:DN051 RS28215
gene id: 2184053:DN051_RS28215
uniprot id: A0A2Z4J4Z7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

2184053:DN051 RS13965
gene id: 2184053:DN051_RS13965
uniprot id: A0A2Z4IZJ2
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

2184053:DN051 RS18435
gene id: 2184053:DN051_RS18435
uniprot id: A0A2Z4IZY6
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

2184053:DN051 RS16775
gene id: 2184053:DN051_RS16775
uniprot id: A0A2Z4J0W4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

2184053:DN051 RS08995
gene id: 2184053:DN051_RS08995
uniprot id: A0A2Z4IW18
names: Subcellular Location Annotation
messages: Membrane

2184053:DN051 RS15870
gene id: 2184053:DN051_RS15870
uniprot id: A0A2Z4IYK9
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

2184053:DN051 RS22565
gene id: 2184053:DN051_RS22565
uniprot id: A0A2Z4J2I0
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

2184053:DN051 RS13000
gene id: 2184053:DN051_RS13000
uniprot id: A0A2Z4IX59
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M4 family.
messages: Extracellular zinc metalloprotease.
messages: Secreted

2184053:DN051 RS31130
gene id: 2184053:DN051_RS31130
uniprot id: A0A2Z4J5T0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

2184053:DN051 RS29705
gene id: 2184053:DN051_RS29705
uniprot id: A0A2Z4J540
names: Similarity
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.

2184053:DN051 RS29590
gene id: 2184053:DN051_RS29590
uniprot id: A0A2Z4J7E6
names: Similarity
messages: Belongs to the band 7/mec-2 family.

2184053:DN051 RS35200
gene id: 2184053:DN051_RS35200
uniprot id: A0A2Z4J886
names: Subcellular Location Annotation
messages: Membrane

2184053:DN051 RS23665
gene id: 2184053:DN051_RS23665
uniprot id: A0A2Z4J2Q3
names: Similarity
messages: Belongs to the peptidase C56 family.

2184053:DN051 RS28790
gene id: 2184053:DN051_RS28790
uniprot id: A0A2Z4J4M5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

2184053:DN051 RS25640
gene id: 2184053:DN051_RS25640
uniprot id: A0A2Z4J359
names: Subcellular Location Annotation
messages: Membrane

2184053:DN051 RS21685
gene id: 2184053:DN051_RS21685
uniprot id: A0A2Z4J1M4
names: Function
names: Similarity
messages: Belongs to the threonine synthase family.
messages: Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.

2184053:DN051 RS31430
gene id: 2184053:DN051_RS31430
uniprot id: A0A2Z4J670
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

2184053:DN051 RS12205
gene id: 2184053:DN051_RS12205
uniprot id: A0A2Z4IWR0
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

2184053:DN051 RS23710
gene id: 2184053:DN051_RS23710
uniprot id: A0A2Z4J268
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2184053:DN051 RS21070
gene id: 2184053:DN051_RS21070
uniprot id: A0A2Z4J0Y5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PstS family.
messages: Part of the ABC transporter complex PstSACB involved in phosphate import.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

2184053:DN051 RS09905
gene id: 2184053:DN051_RS09905
uniprot id: A0A2Z4IWG5
names: Subcellular Location Annotation
messages: Membrane

2184053:DN051 RS16285
gene id: 2184053:DN051_RS16285
uniprot id: A0A2Z4J0N2
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 2 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

2184053:DN051 RS15270
gene id: 2184053:DN051_RS15270
uniprot id: A0A2Z4IZ15
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family. Chitinase class II subfamily.

2184053:DN051 RS13340
gene id: 2184053:DN051_RS13340
uniprot id: A0A2Z4IXL2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

2184053:DN051 RS27420
gene id: 2184053:DN051_RS27420
uniprot id: A0A2Z4J4U2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

2184053:DN051 RS09830
gene id: 2184053:DN051_RS09830
uniprot id: A0A2Z4IVT2
names: Similarity
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Homohexamer. The oligomerization is ATP-dependent.

2184053:DN051 RS25950
gene id: 2184053:DN051_RS25950
uniprot id: A0A2Z4J383
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

2184053:DN051 RS35340
gene id: 2184053:DN051_RS35340
uniprot id: A0A2Z4J831
names: Similarity
messages: Belongs to the AHA1 family.

2184053:DN051 RS03995
gene id: 2184053:DN051_RS03995
uniprot id: A0A2Z4IT36
names: Subcellular Location Annotation
messages: Membrane

2184053:DN051 RS21275
gene id: 2184053:DN051_RS21275
uniprot id: A0A2Z4J179
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

2184053:DN051 RS41050
gene id: 2184053:DN051_RS41050
uniprot id: A0A2Z4JDP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

2184053:DN051 RS08400
gene id: 2184053:DN051_RS08400
uniprot id: A0A2Z4IVJ8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2184053:DN051 RS20345
gene id: 2184053:DN051_RS20345
uniprot id: A0A2Z4J2S1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

2184053:DN051 RS26140
gene id: 2184053:DN051_RS26140
uniprot id: A0A2Z4J484
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

2184053:DN051 RS21830
gene id: 2184053:DN051_RS21830
uniprot id: A0A2Z4J143
names: Function
names: Similarity
messages: Belongs to the MqnA/MqnD family. MqnD subfamily.
messages: Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2).

2184053:DN051 RS08270
gene id: 2184053:DN051_RS08270
uniprot id: A0A2Z4IV87
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

2184053:DN051 RS25825
gene id: 2184053:DN051_RS25825
uniprot id: A0A2Z4J3K9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

2184053:DN051 RS02040
gene id: 2184053:DN051_RS02040
uniprot id: A0A2Z4ISF0
names: Subcellular Location Annotation
messages: Cytoplasm

2184053:DN051 RS05480
gene id: 2184053:DN051_RS05480
uniprot id: A0A2Z4JAP3
names: Subcellular Location Annotation
messages: Cell membrane

2184053:DN051 RS20735
gene id: 2184053:DN051_RS20735
uniprot id: A0A2Z4J108
names: Similarity
messages: Belongs to the SAICAR synthetase family.

2184053:DN051 RS19885
gene id: 2184053:DN051_RS19885
uniprot id: A0A2Z4J0W5
names: Similarity
messages: Belongs to the myo-inositol 1-phosphate synthase family.

2184053:DN051 RS12785
gene id: 2184053:DN051_RS12785
uniprot id: A0A2Z4IXD2
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

2184053:DN051 RS16850
gene id: 2184053:DN051_RS16850
uniprot id: A0A2Z4JB99
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

2184053:DN051 RS27195
gene id: 2184053:DN051_RS27195
uniprot id: A0A2Z4J496
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2184053:DN051 RS19125
gene id: 2184053:DN051_RS19125
uniprot id: A0A2Z4J1C5
names: Similarity
names: Subunit
messages: Belongs to the sigma-70 factor family. ECF subfamily.
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

2184053:DN051 RS15375
gene id: 2184053:DN051_RS15375
uniprot id: A0A2Z4IY54
names: Subcellular Location Annotation
messages: Membrane

2184053:DN051 RS16635
gene id: 2184053:DN051_RS16635
uniprot id: A0A2Z4IZQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2184053:DN051 RS29260
gene id: 2184053:DN051_RS29260
uniprot id: A0A2Z4J4Y7
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

2184053:DN051 RS28850
gene id: 2184053:DN051_RS28850
uniprot id: A0A2Z4J4N5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2184053:DN051 RS14835
gene id: 2184053:DN051_RS14835
uniprot id: A0A2Z4IYU4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

2184053:DN051 RS13370
gene id: 2184053:DN051_RS13370
uniprot id: A0A2Z4IXC2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

2184053:DN051 RS08075
gene id: 2184053:DN051_RS08075
uniprot id: A0A2Z4IUP5
names: Similarity
messages: Belongs to the AHA1 family.

2184053:DN051 RS17150
gene id: 2184053:DN051_RS17150
uniprot id: A0A2Z4J131
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

2184053:DN051 RS12370
gene id: 2184053:DN051_RS12370
uniprot id: A0A2Z4IXK1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

2184053:DN051 RS15915
gene id: 2184053:DN051_RS15915
uniprot id: A0A2Z4IYS3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2184053:DN051 RS20915
gene id: 2184053:DN051_RS20915
uniprot id: A0A2Z4J1F2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the GTP cyclohydrolase II family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.

2184053:DN051 RS25775
gene id: 2184053:DN051_RS25775
uniprot id: A0A2Z4J3K0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S41B family.
messages: Cytoplasm
messages: Degrades oligopeptides.

2184053:DN051 RS18845
gene id: 2184053:DN051_RS18845
uniprot id: A0A2Z4J0Z1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

2184053:DN051 RS05930
gene id: 2184053:DN051_RS05930
uniprot id: A0A2Z4ITE2
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

2184053:DN051 RS18060
gene id: 2184053:DN051_RS18060
uniprot id: A0A2Z4J1K0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2184053:DN051 RS13405
gene id: 2184053:DN051_RS13405
uniprot id: A0A2Z4IXJ7
names: Caution
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

2184053:DN051 RS27840
gene id: 2184053:DN051_RS27840
uniprot id: A0A2Z4J4S1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

2184053:DN051 RS25510
gene id: 2184053:DN051_RS25510
uniprot id: A0A2Z4J337
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

2184053:DN051 RS11940
gene id: 2184053:DN051_RS11940
uniprot id: A0A2Z4IWP1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

2184053:DN051 RS30995
gene id: 2184053:DN051_RS30995
uniprot id: A0A2Z4J668
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SsgA family.
messages: Cell septum

2184053:DN051 RS19815
gene id: 2184053:DN051_RS19815
uniprot id: A0A2Z4J0U4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

2184053:DN051 RS12910
gene id: 2184053:DN051_RS12910
uniprot id: A0A2Z4IXF3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

2184053:DN051 RS13180
gene id: 2184053:DN051_RS13180
uniprot id: A0A2Z4IX85
names: Similarity
messages: Belongs to the UPF0045 family.

2184053:DN051 RS33830
gene id: 2184053:DN051_RS33830
uniprot id: A0A2Z4J737
names: Subcellular Location Annotation
messages: Membrane

2184053:DN051 RS11865
gene id: 2184053:DN051_RS11865
uniprot id: A0A2Z4IXD0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

2184053:DN051 RS32205
gene id: 2184053:DN051_RS32205
uniprot id: A0A2Z4J6D1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Membrane

2184053:DN051 RS26205
gene id: 2184053:DN051_RS26205
uniprot id: A0A2Z4J5X3
names: Subcellular Location Annotation
messages: Membrane

2184053:DN051 RS27685
gene id: 2184053:DN051_RS27685
uniprot id: A0A2Z4JE06
names: Subcellular Location Annotation
messages: Membrane

2184053:DN051 RS25060
gene id: 2184053:DN051_RS25060
uniprot id: A0A2Z4J5B6
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

2184053:DN051 RS34985
gene id: 2184053:DN051_RS34985
uniprot id: A0A2Z4J887
names: Similarity
messages: Belongs to the peptidase S1 family.

2184053:DN051 RS24970
gene id: 2184053:DN051_RS24970
uniprot id: A0A2Z4J432
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

2184053:DN051 RS11410
gene id: 2184053:DN051_RS11410
uniprot id: A0A2Z4JCG0
names: Similarity
messages: Belongs to the Nudix hydrolase family.

2184053:DN051 RS27995
gene id: 2184053:DN051_RS27995
uniprot id: A0A2Z4J4V8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

2184053:DN051 RS30410
gene id: 2184053:DN051_RS30410
uniprot id: A0A2Z4J605
names: Similarity
names: Subunit
messages: Belongs to the AAA ATPase family.
messages: Homohexamer. Assembles into a hexameric ring structure.

2184053:DN051 RS17115
gene id: 2184053:DN051_RS17115
uniprot id: A0A2Z4IZY2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

2184053:DN051 RS41870
gene id: 2184053:DN051_RS41870
uniprot id: A0A2Z4JDC8
names: Similarity
messages: Belongs to the bacterial solute-binding protein 1 family.

2184053:DN051 RS12455
gene id: 2184053:DN051_RS12455
uniprot id: A0A2Z4IX72
names: Function
names: Similarity
messages: Belongs to the CofC family.
messages: Guanylyltransferase that catalyzes the activation of phosphoenolpyruvate (PEP) as enolpyruvoyl-2-diphospho-5'-guanosine, via the condensation of PEP with GTP. It is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor.

2184053:DN051 RS19760
gene id: 2184053:DN051_RS19760
uniprot id: A0A2Z4J0T3
names: Similarity
messages: Belongs to the UPF0232 family.

2184053:DN051 RS08980
gene id: 2184053:DN051_RS08980
uniprot id: A0A2Z4IVD9
names: Function
names: Similarity
messages: Belongs to the bacterial two-domain DSD family.
messages: Catalyzes the conversion of 3-dehydroshikimate to protocatechuate (3,4-dihydroxybenzoate), a common intermediate of quinate and shikimate degradation pathways.

2184053:DN051 RS32840
gene id: 2184053:DN051_RS32840
uniprot id: A0A2Z4J6V5
names: Cofactor
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
messages: Binds 2 nickel ions per subunit.
messages: Carbamylation allows a single lysine to coordinate two nickel ions.
messages: Carboxylation allows a single lysine to coordinate two nickel ions.
messages: Cytoplasm
messages: May form a heterohexamer of 3 UreC (alpha) and 3 UreAB (gamma/beta) subunits. May also form a heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

2184053:DN051 RS22665
gene id: 2184053:DN051_RS22665
uniprot id: A0A2Z4JCC0
names: Similarity
messages: Belongs to the UDPGP type 2 family.

2184053:DN051 RS29095
gene id: 2184053:DN051_RS29095
uniprot id: A0A2Z4J5J9
names: Similarity
messages: Belongs to the DapA family.

2184053:DN051 RS16700
gene id: 2184053:DN051_RS16700
uniprot id: A0A2Z4IZR5
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

2184053:DN051 RS31325
gene id: 2184053:DN051_RS31325
uniprot id: A0A2Z4J602
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2184053:DN051 RS23610
gene id: 2184053:DN051_RS23610
uniprot id: A0A2Z4J2P5
names: Subcellular Location Annotation
messages: Cell membrane

2184053:DN051 RS31475
gene id: 2184053:DN051_RS31475
uniprot id: A0A2Z4J6G2
names: Subcellular Location Annotation
messages: Membrane

2184053:DN051 RS15800
gene id: 2184053:DN051_RS15800
uniprot id: A0A2Z4IZB6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

2184053:DN051 RS12865
gene id: 2184053:DN051_RS12865
uniprot id: A0A2Z4IX24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

2184053:DN051 RS03440
gene id: 2184053:DN051_RS03440
uniprot id: A0A2Z4IT21
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

2184053:DN051 RS13605
gene id: 2184053:DN051_RS13605
uniprot id: A0A2Z4JB30
names: Similarity
messages: Belongs to the thiolase-like superfamily. FabH family.

2184053:DN051 RS06380
gene id: 2184053:DN051_RS06380
uniprot id: A0A2Z4ITN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

2184053:DN051 RS17325
gene id: 2184053:DN051_RS17325
uniprot id: A0A2Z4IZG5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the complex I 75 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

2184053:DN051 RS28865
gene id: 2184053:DN051_RS28865
uniprot id: A0A2Z4J4R5
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2184053:DN051 RS16575
gene id: 2184053:DN051_RS16575
uniprot id: A0A2Z4IZP1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

2184053:DN051 RS14330
gene id: 2184053:DN051_RS14330
uniprot id: A0A2Z4IY22
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

2184053:DN051 RS25360
gene id: 2184053:DN051_RS25360
uniprot id: A0A2Z4J3L2
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

2184053:DN051 RS09675
gene id: 2184053:DN051_RS09675
uniprot id: A0A2Z4IWD1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

2184053:DN051 RS07945
gene id: 2184053:DN051_RS07945
uniprot id: A0A2Z4IUX2
names: Similarity
messages: Belongs to the OsmC/Ohr family.

2184053:DN051 RS28005
gene id: 2184053:DN051_RS28005
uniprot id: A0A2Z4J4U0
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

2184053:DN051 RS08295
gene id: 2184053:DN051_RS08295
uniprot id: A0A2Z4IV26
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

2184053:DN051 RS11440
gene id: 2184053:DN051_RS11440
uniprot id: A0A2Z4IWN4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

2184053:DN051 RS33070
gene id: 2184053:DN051_RS33070
uniprot id: A0A2Z4J927
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Catalyzes the phosphorylation of D-xylulose to D-xylulose 5-phosphate.

2184053:DN051 RS13955
gene id: 2184053:DN051_RS13955
uniprot id: A0A2Z4IXB6
names: Similarity
messages: Belongs to the peptidase C40 family.

2184053:DN051 RS27635
gene id: 2184053:DN051_RS27635
uniprot id: A0A2Z4J6I4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with subunits I, II and III to form cytochrome c oxidase.
messages: Belongs to the cytochrome c oxidase bacterial subunit CtaF family.
messages: Cell membrane
messages: Membrane
messages: Part of cytochrome c oxidase, its function is unknown.

2184053:DN051 RS16865
gene id: 2184053:DN051_RS16865
uniprot id: A0A2Z4IZ64
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

2184053:DN051 RS27140
gene id: 2184053:DN051_RS27140
uniprot id: A0A2Z4J3V9
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2184053:DN051 RS29055
gene id: 2184053:DN051_RS29055
uniprot id: A0A2Z4J5A5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2184053:DN051 RS09195
gene id: 2184053:DN051_RS09195
uniprot id: A0A2Z4IUM4
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily.

2184053:DN051 RS20200
gene id: 2184053:DN051_RS20200
uniprot id: A0A2Z4J0T1
names: Similarity
messages: Belongs to the peptidase M24B family.

2184053:DN051 RS27815
gene id: 2184053:DN051_RS27815
uniprot id: A0A2Z4J502
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterioferritin family.
messages: Homooligomer of 24 subunits, arranged as 12 dimers, that are packed together to form an approximately spherical molecule with a central cavity, in which large amounts of iron can be deposited.
messages: Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex.

2184053:DN051 RS11485
gene id: 2184053:DN051_RS11485
uniprot id: A0A2Z4IY76
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

2184053:DN051 RS13410
gene id: 2184053:DN051_RS13410
uniprot id: A0A2Z4IY28
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

2184053:DN051 RS31135
gene id: 2184053:DN051_RS31135
uniprot id: A0A2Z4J847
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvB family.
messages: Forms a complex with RuvA.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.

2184053:DN051 RS27630
gene id: 2184053:DN051_RS27630
uniprot id: A0A2Z4J417
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
messages: Membrane

2184053:DN051 RS20830
gene id: 2184053:DN051_RS20830
uniprot id: A0A2Z4J2Z8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
messages: Cytoplasm
messages: Homodimer.

2184053:DN051 RS05835
gene id: 2184053:DN051_RS05835
uniprot id: A0A2Z4ITP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2184053:DN051 RS30420
gene id: 2184053:DN051_RS30420
uniprot id: A0A2Z4J600
names: Domain
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic ubiquitin-like protein family.
messages: Is modified by deamidation of its C-terminal glutamine to glutamate by the deamidase Dop, a prerequisite to the subsequent pupylation process.
messages: Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation.
messages: Strongly interacts with the proteasome-associated ATPase ARC through a hydrophobic interface; the interacting region of Pup lies in its C-terminal half. There is one Pup binding site per ARC hexamer ring.
messages: The N-terminal unstructured half of Pup provides a signal required to initiate unfolding and degradation by the proteasome but is not needed for pupylation, while the C-terminal helical half of Pup interacts with ARC to target proteins to the proteasome.

2184053:DN051 RS09310
gene id: 2184053:DN051_RS09310
uniprot id: A0A2Z4IVJ2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhD family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.

2184053:DN051 RS31840
gene id: 2184053:DN051_RS31840
uniprot id: A0A2Z4J6E5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

2184053:DN051 RS14280
gene id: 2184053:DN051_RS14280
uniprot id: A0A2Z4IXY4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

2184053:DN051 RS17540
gene id: 2184053:DN051_RS17540
uniprot id: A0A2Z4IZV0
names: Subcellular Location Annotation
messages: Cytoplasm

2184053:DN051 RS33705
gene id: 2184053:DN051_RS33705
uniprot id: A0A2Z4J797
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RlmG family.
messages: Cytoplasm
messages: Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA.

2184053:DN051 RS36260
gene id: 2184053:DN051_RS36260
uniprot id: A0A2Z4JAQ3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

2184053:DN051 RS26850
gene id: 2184053:DN051_RS26850
uniprot id: A0A2Z4J4B4
names: Subcellular Location Annotation
messages: Membrane

2184053:DN051 RS18200
gene id: 2184053:DN051_RS18200
uniprot id: A0A2Z4IZV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThrE exporter (TC 2.A.79) family.
messages: Membrane

2184053:DN051 RS34415
gene id: 2184053:DN051_RS34415
uniprot id: A0A2Z4JCG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

2184053:DN051 RS22365
gene id: 2184053:DN051_RS22365
uniprot id: A0A2Z4J2X0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

2184053:DN051 RS34330
gene id: 2184053:DN051_RS34330
uniprot id: A0A2Z4J7S2
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

2184053:DN051 RS11225
gene id: 2184053:DN051_RS11225
uniprot id: A0A2Z4IY23
names: Subcellular Location Annotation
messages: Cell membrane

2184053:DN051 RS29195
gene id: 2184053:DN051_RS29195
uniprot id: A0A2Z4J776
names: Function
names: Similarity
messages: Belongs to the acetyltransferase family. EctA subfamily.
messages: Catalyzes the acetylation of L-2,4-diaminobutyrate (DABA) to gamma-N-acetyl-alpha,gamma-diaminobutyric acid (ADABA) with acetyl coenzyme A.

2184053:DN051 RS28150
gene id: 2184053:DN051_RS28150
uniprot id: A0A2Z4J4E4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Involved in both the histidine and tryptophan biosynthetic pathways.

2184053:DN051 RS15995
gene id: 2184053:DN051_RS15995
uniprot id: A0A2Z4IYS2
names: Similarity
names: Subunit
messages: Belongs to the CMP-NeuNAc synthase family.
messages: Belongs to the KdsC family.
messages: Homotetramer.

2184053:DN051 RS08210
gene id: 2184053:DN051_RS08210
uniprot id: A0A2Z4IV73
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

2184053:DN051 RS23510
gene id: 2184053:DN051_RS23510
uniprot id: A0A2Z4J1Z8
names: Similarity
messages: Belongs to the phosphohexose mutase family.

2184053:DN051 RS22010
gene id: 2184053:DN051_RS22010
uniprot id: A0A2Z4J1D1
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

2184053:DN051 RS23290
gene id: 2184053:DN051_RS23290
uniprot id: A0A2Z4J213
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-dependent hydrolases superfamily. HutI family.
messages: Binds 1 zinc or iron ion per subunit.
messages: Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate. It is the third step in the universal histidine degradation pathway.
messages: Cytoplasm

2184053:DN051 RS24610
gene id: 2184053:DN051_RS24610
uniprot id: A0A2Z4J329
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

2184053:DN051 RS19080
gene id: 2184053:DN051_RS19080
uniprot id: A0A2Z4J038
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2184053:DN051 RS15235
gene id: 2184053:DN051_RS15235
uniprot id: A0A2Z4IYH1
names: Subcellular Location Annotation
messages: Membrane

2184053:DN051 RS10135
gene id: 2184053:DN051_RS10135
uniprot id: A0A2Z4IVY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

2184053:DN051 RS23480
gene id: 2184053:DN051_RS23480
uniprot id: A0A2Z4J235
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

2184053:DN051 RS35720
gene id: 2184053:DN051_RS35720
uniprot id: A0A2Z4J888
names: Subunit
messages: Homodimer.

2184053:DN051 RS10405
gene id: 2184053:DN051_RS10405
uniprot id: A0A2Z4IXP7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.
messages: Cytoplasm

2184053:DN051 RS09760
gene id: 2184053:DN051_RS09760
uniprot id: A0A2Z4IUW7
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

2184053:DN051 RS32460
gene id: 2184053:DN051_RS32460
uniprot id: A0A2Z4J804
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

2184053:DN051 RS09635
gene id: 2184053:DN051_RS09635
uniprot id: A0A2Z4IVV6
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain.

2184053:DN051 RS39945
gene id: 2184053:DN051_RS39945
uniprot id: A0A2Z4IRG6
names: Subcellular Location Annotation
messages: Cell membrane

2184053:DN051 RS10495
gene id: 2184053:DN051_RS10495
uniprot id: A0A2Z4IWQ3
names: Cofactor
names: PTM
names: Similarity
messages: Belongs to the copper/topaquinone oxidase family.
messages: Contains 1 topaquinone per subunit.
messages: Topaquinone (TPQ) is generated by copper-dependent autoxidation of a specific tyrosyl residue.

2184053:DN051 RS12650
gene id: 2184053:DN051_RS12650
uniprot id: A0A2Z4IXR1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterohexamer of 3 UreC (alpha) and 3 UreAB (gamma/beta) subunits.
messages: In the C-terminal section; belongs to the urease beta subunit family.
messages: In the N-terminal section; belongs to the urease gamma subunit family.

2184053:DN051 RS12085
gene id: 2184053:DN051_RS12085
uniprot id: A0A2Z4IWN9
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

2184053:DN051 RS21095
gene id: 2184053:DN051_RS21095
uniprot id: A0A2Z4J1I0
names: Similarity
messages: Belongs to the PhoU family.
messages: Belongs to the UPF0111 family.

2184053:DN051 RS31290
gene id: 2184053:DN051_RS31290
uniprot id: A0A2Z4J661
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

2184053:DN051 RS17350
gene id: 2184053:DN051_RS17350
uniprot id: A0A2Z4IZ63
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

2184053:DN051 RS10255
gene id: 2184053:DN051_RS10255
uniprot id: A0A2Z4IVS1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

2184053:DN051 RS26070
gene id: 2184053:DN051_RS26070
uniprot id: A0A2Z4J5U9
names: Function
messages: Catalyzes the reduction of sulfite to sulfide, a step in the biosynthesis of sulfur-containing amino acids and cofactors.

2184053:DN051 RS13055
gene id: 2184053:DN051_RS13055
uniprot id: A0A2Z4IZ14
names: Similarity
messages: Belongs to the thioredoxin family.

2184053:DN051 RS26010
gene id: 2184053:DN051_RS26010
uniprot id: A0A2Z4J3B3
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

2184053:DN051 RS14860
gene id: 2184053:DN051_RS14860
uniprot id: A0A2Z4J000
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

2184053:DN051 RS25395
gene id: 2184053:DN051_RS25395
uniprot id: A0A2Z4J3F5
names: Function
names: Similarity
messages: Belongs to the MreC family.
messages: Involved in formation and maintenance of cell shape.

2184053:DN051 RS43525
gene id: 2184053:DN051_RS43525
uniprot id: A0A2Z4JGH6
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit A family.

2184053:DN051 RS20100
gene id: 2184053:DN051_RS20100
uniprot id: A0A2Z4J0C7
names: Function
names: Similarity
messages: Belongs to the KptA/TPT1 family.
messages: Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP-ribose 1''-2''-cyclic phosphate (APPR>P). May function as an ADP-ribosylase.

2184053:DN051 RS19400
gene id: 2184053:DN051_RS19400
uniprot id: A0A2Z4J0Q5
names: Similarity
messages: Belongs to the peptidase M18 family.

2184053:DN051 RS27565
gene id: 2184053:DN051_RS27565
uniprot id: A0A2Z4J406
names: Similarity
messages: Belongs to the PspA/IM30 family.

2184053:DN051 RS04180
gene id: 2184053:DN051_RS04180
uniprot id: A0A2Z4ISX3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

2184053:DN051 RS35520
gene id: 2184053:DN051_RS35520
uniprot id: A0A2Z4J8E2
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

2184053:DN051 RS29105
gene id: 2184053:DN051_RS29105
uniprot id: A0A2Z4J5E0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2184053:DN051 RS29805
gene id: 2184053:DN051_RS29805
uniprot id: A0A2Z4J5M3
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

2184053:DN051 RS17390
gene id: 2184053:DN051_RS17390
uniprot id: A0A2Z4IZI7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the radical SAM superfamily. MqnC family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2).

2184053:DN051 RS27155
gene id: 2184053:DN051_RS27155
uniprot id: A0A2Z4J5B2
names: Similarity
messages: Belongs to the glutamine synthetase family.

2184053:DN051 RS18705
gene id: 2184053:DN051_RS18705
uniprot id: A0A2Z4IZW9
names: Subcellular Location Annotation
messages: Membrane

2184053:DN051 RS14735
gene id: 2184053:DN051_RS14735
uniprot id: A0A2Z4IY36
names: Cofactor
names: Function
messages: Binds 1 [3Fe-4S] cluster.
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

2184053:DN051 RS17645
gene id: 2184053:DN051_RS17645
uniprot id: A0A2Z4IZD8
names: Subcellular Location Annotation
messages: Membrane

2184053:DN051 RS20820
gene id: 2184053:DN051_RS20820
uniprot id: A0A2Z4J0P5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

2184053:DN051 RS18275
gene id: 2184053:DN051_RS18275
uniprot id: A0A2Z4IZQ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

2184053:DN051 RS36630
gene id: 2184053:DN051_RS36630
uniprot id: A0A2Z4J8Z5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2184053:DN051 RS15005
gene id: 2184053:DN051_RS15005
uniprot id: A0A2Z4IYD3
names: Similarity
messages: Belongs to the FBPase class 2 family.

2184053:DN051 RS20815
gene id: 2184053:DN051_RS20815
uniprot id: A0A2Z4J1D9
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

2184053:DN051 RS06905
gene id: 2184053:DN051_RS06905
uniprot id: A0A2Z4IUW1
names: Similarity
messages: Belongs to the universal stress protein A family.

2184053:DN051 RS30750
gene id: 2184053:DN051_RS30750
uniprot id: A0A2Z4J5Q8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

2184053:DN051 RS25385
gene id: 2184053:DN051_RS25385
uniprot id: A0A2Z4J2Z9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

2184053:DN051 RS12705
gene id: 2184053:DN051_RS12705
uniprot id: A0A2Z4IXS1
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

2184053:DN051 RS16470
gene id: 2184053:DN051_RS16470
uniprot id: A0A2Z4IZL8
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

2184053:DN051 RS16890
gene id: 2184053:DN051_RS16890
uniprot id: A0A2Z4IZJ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

2184053:DN051 RS14830
gene id: 2184053:DN051_RS14830
uniprot id: A0A2Z4IYB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

2184053:DN051 RS26360
gene id: 2184053:DN051_RS26360
uniprot id: A0A2Z4J601
names: Subcellular Location Annotation
messages: Membrane

2184053:DN051 RS27705
gene id: 2184053:DN051_RS27705
uniprot id: A0A2Z4J4Y5
names: Similarity
messages: Belongs to the peptidase C40 family.

2184053:DN051 RS05280
gene id: 2184053:DN051_RS05280
uniprot id: A0A2Z4ITP8
names: Subcellular Location Annotation
messages: Membrane

2184053:DN051 RS25850
gene id: 2184053:DN051_RS25850
uniprot id: A0A2Z4JBQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

2184053:DN051 RS28905
gene id: 2184053:DN051_RS28905
uniprot id: A0A2Z4J4P1
names: Subcellular Location Annotation
messages: Membrane

2184053:DN051 RS33385
gene id: 2184053:DN051_RS33385
uniprot id: A0A2Z4J7R6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

2184053:DN051 RS12255
gene id: 2184053:DN051_RS12255
uniprot id: A0A2Z4IWS1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein S19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein S19.

2184053:DN051 RS04825
gene id: 2184053:DN051_RS04825
uniprot id: A0A2Z4ISV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2184053:DN051 RS28310
gene id: 2184053:DN051_RS28310
uniprot id: A0A2Z4J4E0
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

2184053:DN051 RS18175
gene id: 2184053:DN051_RS18175
uniprot id: A0A2Z4J062
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

2184053:DN051 RS31750
gene id: 2184053:DN051_RS31750
uniprot id: A0A2Z4J6Z5
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

2184053:DN051 RS31180
gene id: 2184053:DN051_RS31180
uniprot id: A0A2Z4J5T9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

2184053:DN051 RS11020
gene id: 2184053:DN051_RS11020
uniprot id: A0A2Z4IWX9
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

2184053:DN051 RS17790
gene id: 2184053:DN051_RS17790
uniprot id: A0A2Z4IZQ0
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

2184053:DN051 RS31260
gene id: 2184053:DN051_RS31260
uniprot id: A0A2Z4J7D6
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

2184053:DN051 RS24015
gene id: 2184053:DN051_RS24015
uniprot id: A0A2Z4J2B9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2184053:DN051 RS29100
gene id: 2184053:DN051_RS29100
uniprot id: A0A2Z4JE35
names: Similarity
messages: Belongs to the IlvD/Edd family.

2184053:DN051 RS16535
gene id: 2184053:DN051_RS16535
uniprot id: A0A2Z4IZ16
names: Similarity
messages: Belongs to the IMPDH/GMPR family.

2184053:DN051 RS27270
gene id: 2184053:DN051_RS27270
uniprot id: A0A2Z4J5D5
names: Similarity
messages: Belongs to the glutamine synthetase family.

2184053:DN051 RS09040
gene id: 2184053:DN051_RS09040
uniprot id: A0A2Z4IV61
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the GTP cyclohydrolase II family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.

2184053:DN051 RS32845
gene id: 2184053:DN051_RS32845
uniprot id: A0A2Z4J6M9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UreF family.
messages: Cytoplasm
messages: Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
messages: UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

2184053:DN051 RS20180
gene id: 2184053:DN051_RS20180
uniprot id: A0A2Z4J0K4
names: Similarity
messages: Belongs to the SCO1/2 family.

2184053:DN051 RS31185
gene id: 2184053:DN051_RS31185
uniprot id: A0A2Z4J860
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VKOR family.
messages: Membrane

2184053:DN051 RS24055
gene id: 2184053:DN051_RS24055
uniprot id: A0A2Z4J2P7
names: Subcellular Location Annotation
messages: Membrane

2184053:DN051 RS30910
gene id: 2184053:DN051_RS30910
uniprot id: A0A2Z4J658
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

2184053:DN051 RS08030
gene id: 2184053:DN051_RS08030
uniprot id: A0A2Z4IV41
names: Cofactor
names: Similarity
messages: Belongs to the monomeric-type IDH family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

2184053:DN051 RS11325
gene id: 2184053:DN051_RS11325
uniprot id: A0A2Z4IY44
names: Similarity
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.

2184053:DN051 RS16645
gene id: 2184053:DN051_RS16645
uniprot id: A0A2Z4IZ91
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

2184053:DN051 RS37810
gene id: 2184053:DN051_RS37810
uniprot id: A0A2Z4J988
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

2184053:DN051 RS13115
gene id: 2184053:DN051_RS13115
uniprot id: A0A2Z4IZ21
names: Similarity
names: Subunit
messages: Belongs to the pyruvate kinase family.
messages: Homotetramer.

2184053:DN051 RS04065
gene id: 2184053:DN051_RS04065
uniprot id: A0A2Z4ITQ9
names: Subcellular Location Annotation
messages: Membrane

2184053:DN051 RS09540
gene id: 2184053:DN051_RS09540
uniprot id: A0A2Z4IXD5
names: Similarity
messages: Belongs to the peptidase S66 family.

2184053:DN051 RS17050
gene id: 2184053:DN051_RS17050
uniprot id: A0A2Z4IZX7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

2184053:DN051 RS09155
gene id: 2184053:DN051_RS09155
uniprot id: A0A2Z4IV83
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

2184053:DN051 RS08925
gene id: 2184053:DN051_RS08925
uniprot id: A0A2Z4IV45
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

2184053:DN051 RS25205
gene id: 2184053:DN051_RS25205
uniprot id: A0A2Z4J2T8
names: Similarity
messages: Belongs to the peptidase M1 family.

2184053:DN051 RS28435
gene id: 2184053:DN051_RS28435
uniprot id: A0A2Z4J4G3
names: Subcellular Location Annotation
messages: Membrane

2184053:DN051 RS13580
gene id: 2184053:DN051_RS13580
uniprot id: A0A2Z4IY57
names: Similarity
messages: Belongs to the arylamine N-acetyltransferase family.

2184053:DN051 RS10180
gene id: 2184053:DN051_RS10180
uniprot id: A0A2Z4IV25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Membrane

2184053:DN051 RS31015
gene id: 2184053:DN051_RS31015
uniprot id: A0A2Z4J5R2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2184053:DN051 RS27660
gene id: 2184053:DN051_RS27660
uniprot id: A0A2Z4J5K8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Rieske iron-sulfur protein family.
messages: Cell membrane
messages: Iron-sulfur subunit of the cytochrome bc1 complex, an essential component of the respiratory electron transport chain required for ATP synthesis. The bc1 complex catalyzes the oxidation of menaquinol and the reduction of cytochrome c in the respiratory chain. The bc1 complex operates through a Q-cycle mechanism that couples electron transfer to generation of the proton gradient that drives ATP synthesis.
messages: Membrane

2184053:DN051 RS23645
gene id: 2184053:DN051_RS23645
uniprot id: A0A2Z4J4J9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

2184053:DN051 RS34505
gene id: 2184053:DN051_RS34505
uniprot id: A0A2Z4J848
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2184053:DN051 RS08485
gene id: 2184053:DN051_RS08485
uniprot id: A0A2Z4IV58
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

2184053:DN051 RS31295
gene id: 2184053:DN051_RS31295
uniprot id: A0A2Z4J5Y3
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2184053:DN051 RS28695
gene id: 2184053:DN051_RS28695
uniprot id: A0A2Z4J6Y6
names: Subcellular Location Annotation
messages: Membrane

2184053:DN051 RS19685
gene id: 2184053:DN051_RS19685
uniprot id: A0A2Z4J0U8
names: Similarity
messages: Belongs to the UPF0749 family.

2184053:DN051 RS04350
gene id: 2184053:DN051_RS04350
uniprot id: A0A2Z4IUR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SsgA family.
messages: Cell septum

2184053:DN051 RS10620
gene id: 2184053:DN051_RS10620
uniprot id: A0A2Z4IW29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2184053:DN051 RS17885
gene id: 2184053:DN051_RS17885
uniprot id: A0A2Z4JBP5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.

2184053:DN051 RS28665
gene id: 2184053:DN051_RS28665
uniprot id: A0A2Z4J564
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

2184053:DN051 RS30525
gene id: 2184053:DN051_RS30525
uniprot id: A0A2Z4J617
names: Similarity
messages: Belongs to the cytochrome P450 family.

2184053:DN051 RS28290
gene id: 2184053:DN051_RS28290
uniprot id: A0A2Z4J4Y8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

2184053:DN051 RS29740
gene id: 2184053:DN051_RS29740
uniprot id: A0A2Z4J6N2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AlaDH/PNT family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reductive amination of pyruvate to L-alanine.

2184053:DN051 RS31970
gene id: 2184053:DN051_RS31970
uniprot id: A0A2Z4J698
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

2184053:DN051 RS29340
gene id: 2184053:DN051_RS29340
uniprot id: A0A2Z4J5F8
names: Subcellular Location Annotation
messages: Membrane

2184053:DN051 RS16210
gene id: 2184053:DN051_RS16210
uniprot id: A0A2Z4IYR1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2184053:DN051 RS21580
gene id: 2184053:DN051_RS21580
uniprot id: A0A2Z4J2I7
names: Subcellular Location Annotation
messages: Membrane

2184053:DN051 RS05100
gene id: 2184053:DN051_RS05100
uniprot id: A0A2Z4ISJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0719 family.
messages: Membrane

2184053:DN051 RS21785
gene id: 2184053:DN051_RS21785
uniprot id: A0A2Z4J1T5
names: Similarity
messages: Belongs to the helicase family. RAD25/XPB subfamily.

2184053:DN051 RS15450
gene id: 2184053:DN051_RS15450
uniprot id: A0A2Z4IZ34
names: Similarity
messages: Belongs to the serine/threonine dehydratase family.

2184053:DN051 RS24675
gene id: 2184053:DN051_RS24675
uniprot id: A0A2Z4J371
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

2184053:DN051 RS13630
gene id: 2184053:DN051_RS13630
uniprot id: A0A2Z4IXG7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

2184053:DN051 RS11515
gene id: 2184053:DN051_RS11515
uniprot id: A0A2Z4IX73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2184053:DN051 RS26755
gene id: 2184053:DN051_RS26755
uniprot id: A0A2Z4JC95
names: Similarity
messages: Belongs to the cytochrome P450 family.

2184053:DN051 RS30520
gene id: 2184053:DN051_RS30520
uniprot id: A0A2Z4J710
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

2184053:DN051 RS41455
gene id: 2184053:DN051_RS41455
uniprot id: A0A2Z4JDN5
names: Subcellular Location Annotation
messages: Membrane

2184053:DN051 RS28640
gene id: 2184053:DN051_RS28640
uniprot id: A0A2Z4J6X8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

2184053:DN051 RS23745
gene id: 2184053:DN051_RS23745
uniprot id: A0A2Z4J238
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF2.
messages: Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.

2184053:DN051 RS16560
gene id: 2184053:DN051_RS16560
uniprot id: A0A2Z4IZ95
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

2184053:DN051 RS04625
gene id: 2184053:DN051_RS04625
uniprot id: A0A2Z4ITF7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class II aldolase/RraA-like family.
messages: Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2-oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions.
messages: Homotrimer.

2184053:DN051 RS25475
gene id: 2184053:DN051_RS25475
uniprot id: A0A2Z4J3E8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gas vesicle protein type A family.
messages: Gas vesicles are small, hollow, gas filled protein structures that are found in several microbial planktonic microorganisms. They allow the positioning of the organism at the favorable depth for growth. GvpA type proteins form the essential core of the structure.
messages: gas vesicle membrane

2184053:DN051 RS06315
gene id: 2184053:DN051_RS06315
uniprot id: A0A2Z4IU66
names: Subcellular Location Annotation
messages: Membrane

2184053:DN051 RS13360
gene id: 2184053:DN051_RS13360
uniprot id: A0A2Z4IY09
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

2184053:DN051 RS34070
gene id: 2184053:DN051_RS34070
uniprot id: A0A2Z4J9J3
names: Similarity
names: Subunit
messages: Belongs to the glutaminase family.
messages: Homotetramer.

2184053:DN051 RS10775
gene id: 2184053:DN051_RS10775
uniprot id: A0A2Z4IW00
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2184053:DN051 RS27615
gene id: 2184053:DN051_RS27615
uniprot id: A0A2Z4J4L5
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

2184053:DN051 RS09835
gene id: 2184053:DN051_RS09835
uniprot id: A0A2Z4IVJ5
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaved by autocatalysis into a large and a small subunit.
messages: This enzyme consists of two polypeptide chains, which are synthesized in precursor form from a single polypeptide.

2184053:DN051 RS22180
gene id: 2184053:DN051_RS22180
uniprot id: A0A2Z4J1F6
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

2184053:DN051 RS05995
gene id: 2184053:DN051_RS05995
uniprot id: A0A2Z4ITF3
names: Similarity
messages: Belongs to the AHA1 family.

2184053:DN051 RS31960
gene id: 2184053:DN051_RS31960
uniprot id: A0A2Z4J8K2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpC family.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

2184053:DN051 RS11480
gene id: 2184053:DN051_RS11480
uniprot id: A0A2Z4IWD6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

2184053:DN051 RS31355
gene id: 2184053:DN051_RS31355
uniprot id: A0A2Z4J6K6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

2184053:DN051 RS16765
gene id: 2184053:DN051_RS16765
uniprot id: A0A2Z4IYV3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

2184053:DN051 RS34450
gene id: 2184053:DN051_RS34450
uniprot id: A0A2Z4J7M7
names: Subcellular Location Annotation
messages: Membrane

2184053:DN051 RS23225
gene id: 2184053:DN051_RS23225
uniprot id: A0A2Z4J2I5
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

2184053:DN051 RS23910
gene id: 2184053:DN051_RS23910
uniprot id: A0A2Z4J2R7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2184053:DN051 RS08690
gene id: 2184053:DN051_RS08690
uniprot id: A0A2Z4IUC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SsgA family.
messages: Cell septum

2184053:DN051 RS34785
gene id: 2184053:DN051_RS34785
uniprot id: A0A2Z4J9Z4
names: Function
names: Similarity
messages: ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.
messages: Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.

2184053:DN051 RS29440
gene id: 2184053:DN051_RS29440
uniprot id: A0A2Z4J506
names: Similarity
messages: Belongs to the peptidase S8 family.

2184053:DN051 RS16875
gene id: 2184053:DN051_RS16875
uniprot id: A0A2Z4IYX3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

2184053:DN051 RS09480
gene id: 2184053:DN051_RS09480
uniprot id: A0A2Z4IVM2
names: Function
names: Subcellular Location Annotation
messages: May play a structural or regulatory role in gas vesicle synthesis.
messages: Vesicle
messages: gas vesicle

2184053:DN051 RS04325
gene id: 2184053:DN051_RS04325
uniprot id: A0A2Z4ITM1
names: Subcellular Location Annotation
messages: Membrane

2184053:DN051 RS06250
gene id: 2184053:DN051_RS06250
uniprot id: A0A2Z4IT47
names: Subcellular Location Annotation
messages: Membrane

2184053:DN051 RS29890
gene id: 2184053:DN051_RS29890
uniprot id: A0A2Z4J581
names: Similarity
messages: Belongs to the peptidase S1 family.

2184053:DN051 RS30640
gene id: 2184053:DN051_RS30640
uniprot id: A0A2Z4J5Y0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

2184053:DN051 RS17290
gene id: 2184053:DN051_RS17290
uniprot id: A0A2Z4IZH0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

2184053:DN051 RS29110
gene id: 2184053:DN051_RS29110
uniprot id: A0A2Z4J6D0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2184053:DN051 RS22230
gene id: 2184053:DN051_RS22230
uniprot id: A0A2Z4J210
names: Similarity
messages: Belongs to the F420H(2)-dependent quinone reductase family.

2184053:DN051 RS19790
gene id: 2184053:DN051_RS19790
uniprot id: A0A2Z4J0F2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

2184053:DN051 RS12025
gene id: 2184053:DN051_RS12025
uniprot id: A0A2Z4IWM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2184053:DN051 RS15370
gene id: 2184053:DN051_RS15370
uniprot id: A0A2Z4IYD2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.
messages: Cytoplasm
messages: Monomer.

2184053:DN051 RS18695
gene id: 2184053:DN051_RS18695
uniprot id: A0A2Z4J040
names: Subcellular Location Annotation
messages: Membrane

2184053:DN051 RS30090
gene id: 2184053:DN051_RS30090
uniprot id: A0A2Z4J7N6
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

2184053:DN051 RS13040
gene id: 2184053:DN051_RS13040
uniprot id: A0A2Z4IX66
names: Similarity
names: Subunit
messages: Belongs to the aminoglycoside phosphotransferase family.
messages: Monomer.

2184053:DN051 RS16695
gene id: 2184053:DN051_RS16695
uniprot id: A0A2Z4IZ96
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

2184053:DN051 RS25925
gene id: 2184053:DN051_RS25925
uniprot id: A0A2Z4J444
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

2184053:DN051 RS22815
gene id: 2184053:DN051_RS22815
uniprot id: A0A2Z4J346
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Belongs to the precorrin methyltransferase family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

2184053:DN051 RS13445
gene id: 2184053:DN051_RS13445
uniprot id: A0A2Z4IXM8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

2184053:DN051 RS18935
gene id: 2184053:DN051_RS18935
uniprot id: A0A2Z4J0I6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.

2184053:DN051 RS30415
gene id: 2184053:DN051_RS30415
uniprot id: A0A2Z4J6Y8
names: Similarity
messages: Belongs to the Pup ligase/Pup deamidase family. Pup deamidase subfamily.

2184053:DN051 RS29245
gene id: 2184053:DN051_RS29245
uniprot id: A0A2Z4J4V5
names: Similarity
messages: Belongs to the CobH/CbiC family.

2184053:DN051 RS24300
gene id: 2184053:DN051_RS24300
uniprot id: A0A2Z4J2C4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

2184053:DN051 RS17345
gene id: 2184053:DN051_RS17345
uniprot id: A0A2Z4IZ32
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 30 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

2184053:DN051 RS12825
gene id: 2184053:DN051_RS12825
uniprot id: A0A2Z4IX97
names: Similarity
messages: Belongs to the LOG family.

2184053:DN051 RS11400
gene id: 2184053:DN051_RS11400
uniprot id: A0A2Z4IWK2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2184053:DN051 RS16845
gene id: 2184053:DN051_RS16845
uniprot id: A0A2Z4IZU2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

2184053:DN051 RS15955
gene id: 2184053:DN051_RS15955
uniprot id: A0A2Z4IYT9
names: Subcellular Location Annotation
messages: Membrane

2184053:DN051 RS16745
gene id: 2184053:DN051_RS16745
uniprot id: A0A2Z4IZA0
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

2184053:DN051 RS19990
gene id: 2184053:DN051_RS19990
uniprot id: A0A2Z4J0Y9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2184053:DN051 RS05600
gene id: 2184053:DN051_RS05600
uniprot id: A0A2Z4IVI5
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

2184053:DN051 RS18425
gene id: 2184053:DN051_RS18425
uniprot id: A0A2Z4J059
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-insensitive subfamily.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force.

2184053:DN051 RS18295
gene id: 2184053:DN051_RS18295
uniprot id: A0A2Z4J0H9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

2184053:DN051 RS21645
gene id: 2184053:DN051_RS21645
uniprot id: A0A2Z4J1C9
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

2184053:DN051 RS36685
gene id: 2184053:DN051_RS36685
uniprot id: A0A2Z4J919
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

2184053:DN051 RS41280
gene id: 2184053:DN051_RS41280
uniprot id: A0A2Z4JD41
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

2184053:DN051 RS12320
gene id: 2184053:DN051_RS12320
uniprot id: A0A2Z4IXJ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

2184053:DN051 RS15055
gene id: 2184053:DN051_RS15055
uniprot id: A0A2Z4IYE2
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

2184053:DN051 RS17855
gene id: 2184053:DN051_RS17855
uniprot id: A0A2Z4IZA1
names: Subcellular Location Annotation
messages: Membrane

2184053:DN051 RS31700
gene id: 2184053:DN051_RS31700
uniprot id: A0A2Z4J6M6
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

2184053:DN051 RS18755
gene id: 2184053:DN051_RS18755
uniprot id: A0A2Z4J050
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SURF1 family.
messages: Cell membrane

2184053:DN051 RS31635
gene id: 2184053:DN051_RS31635
uniprot id: A0A2Z4J7L8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LamB/PxpA family.
messages: Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
messages: Forms a complex composed of PxpA, PxpB and PxpC.

2184053:DN051 RS34860
gene id: 2184053:DN051_RS34860
uniprot id: A0A2Z4J931
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

2184053:DN051 RS15880
gene id: 2184053:DN051_RS15880
uniprot id: A0A2Z4IYJ2
names: Subcellular Location Annotation
messages: Cell membrane

2184053:DN051 RS20515
gene id: 2184053:DN051_RS20515
uniprot id: A0A2Z4J0S8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2184053:DN051 RS12180
gene id: 2184053:DN051_RS12180
uniprot id: A0A2Z4IWS4
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

2184053:DN051 RS43895
gene id: 2184053:DN051_RS43895
uniprot id: A0A2Z4JEX4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
messages: Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD).

2184053:DN051 RS23915
gene id: 2184053:DN051_RS23915
uniprot id: A0A2Z4J298
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

2184053:DN051 RS16980
gene id: 2184053:DN051_RS16980
uniprot id: A0A2Z4IZ61
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

2184053:DN051 RS23520
gene id: 2184053:DN051_RS23520
uniprot id: A0A2Z4J4I2
names: Similarity
messages: Belongs to the PGI/PMI family.

2184053:DN051 RS18770
gene id: 2184053:DN051_RS18770
uniprot id: A0A2Z4J1X2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2184053:DN051 RS11200
gene id: 2184053:DN051_RS11200
uniprot id: A0A2Z4IWK5
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

2184053:DN051 RS13375
gene id: 2184053:DN051_RS13375
uniprot id: A0A2Z4IX00
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

2184053:DN051 RS21265
gene id: 2184053:DN051_RS21265
uniprot id: A0A2Z4J1G6
names: Similarity
messages: Belongs to the Fur family.

2184053:DN051 RS30435
gene id: 2184053:DN051_RS30435
uniprot id: A0A2Z4J5K9
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
messages: Cytoplasm
messages: The 20S proteasome core is composed of 14 alpha and 14 beta subunits that assemble into four stacked heptameric rings, resulting in a barrel-shaped structure. The two inner rings, each composed of seven catalytic beta subunits, are sandwiched by two outer rings, each composed of seven alpha subunits. The catalytic chamber with the active sites is on the inside of the barrel. Has a gated structure, the ends of the cylinder being occluded by the N-termini of the alpha-subunits. Is capped by the proteasome-associated ATPase, ARC.
messages: The formation of the proteasomal ATPase ARC-20S proteasome complex, likely via the docking of the C-termini of ARC into the intersubunit pockets in the alpha-rings, may trigger opening of the gate for substrate entry. Interconversion between the open-gate and close-gate conformations leads to a dynamic regulation of the 20S proteasome proteolysis activity.

2184053:DN051 RS17600
gene id: 2184053:DN051_RS17600
uniprot id: A0A2Z4IZV8
names: Similarity
messages: Belongs to the UbiD family.

2184053:DN051 RS06095
gene id: 2184053:DN051_RS06095
uniprot id: A0A2Z4ITH3
names: Similarity
messages: Belongs to the F420H(2)-dependent quinone reductase family.

2184053:DN051 RS27980
gene id: 2184053:DN051_RS27980
uniprot id: A0A2Z4J4N2
names: Subcellular Location Annotation
messages: Membrane

2184053:DN051 RS09150
gene id: 2184053:DN051_RS09150
uniprot id: A0A2Z4IVG6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

2184053:DN051 RS29045
gene id: 2184053:DN051_RS29045
uniprot id: A0A2Z4J5D0
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

2184053:DN051 RS17975
gene id: 2184053:DN051_RS17975
uniprot id: A0A2Z4JBL4
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

2184053:DN051 RS16615
gene id: 2184053:DN051_RS16615
uniprot id: A0A2Z4IYW7
names: Similarity
messages: Belongs to the YciI family.

2184053:DN051 RS08755
gene id: 2184053:DN051_RS08755
uniprot id: A0A2Z4IUV3
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

2184053:DN051 RS31905
gene id: 2184053:DN051_RS31905
uniprot id: A0A2Z4J6H7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

2184053:DN051 RS14325
gene id: 2184053:DN051_RS14325
uniprot id: A0A2Z4IZQ8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

2184053:DN051 RS11035
gene id: 2184053:DN051_RS11035
uniprot id: A0A2Z4IWH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

2184053:DN051 RS41080
gene id: 2184053:DN051_RS41080
uniprot id: A0A2Z4JD08
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

2184053:DN051 RS17100
gene id: 2184053:DN051_RS17100
uniprot id: A0A2Z4IZM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

2184053:DN051 RS09065
gene id: 2184053:DN051_RS09065
uniprot id: A0A2Z4IVM5
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.

2184053:DN051 RS33230
gene id: 2184053:DN051_RS33230
uniprot id: A0A2Z4J6X3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2184053:DN051 RS32180
gene id: 2184053:DN051_RS32180
uniprot id: A0A2Z4J8N9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

2184053:DN051 RS22105
gene id: 2184053:DN051_RS22105
uniprot id: A0A2Z4J184
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

2184053:DN051 RS12260
gene id: 2184053:DN051_RS12260
uniprot id: A0A2Z4IXJ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: A probable RNA-binding protein.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm

2184053:DN051 RS10410
gene id: 2184053:DN051_RS10410
uniprot id: A0A2Z4IW32
names: Caution
names: Function
names: Similarity
messages: Belongs to the APS kinase family.
messages: Catalyzes the synthesis of activated sulfate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2184053:DN051 RS20310
gene id: 2184053:DN051_RS20310
uniprot id: A0A2Z4J209
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

2184053:DN051 RS26470
gene id: 2184053:DN051_RS26470
uniprot id: A0A2Z4J3Y7
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

2184053:DN051 RS08555
gene id: 2184053:DN051_RS08555
uniprot id: A0A2Z4IVS8
names: Cofactor
messages: Binds 1 zinc ion per subunit.

2184053:DN051 RS30890
gene id: 2184053:DN051_RS30890
uniprot id: A0A2Z4J5Q6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nlpA lipoprotein family.
messages: Membrane

2184053:DN051 RS22090
gene id: 2184053:DN051_RS22090
uniprot id: A0A2Z4J1K5
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

2184053:DN051 RS05360
gene id: 2184053:DN051_RS05360
uniprot id: A0A2Z4JB29
names: Similarity
messages: Belongs to the UDPGP type 2 family.

2184053:DN051 RS14990
gene id: 2184053:DN051_RS14990
uniprot id: A0A2Z4IYY5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

2184053:DN051 RS14060
gene id: 2184053:DN051_RS14060
uniprot id: A0A2Z4IXY5
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

2184053:DN051 RS30445
gene id: 2184053:DN051_RS30445
uniprot id: A0A2Z4J7U2
names: Subcellular Location Annotation
messages: Membrane

2184053:DN051 RS28020
gene id: 2184053:DN051_RS28020
uniprot id: A0A2Z4J486
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DivIVA family.
messages: Cytoplasm

2184053:DN051 RS16410
gene id: 2184053:DN051_RS16410
uniprot id: A0A2Z4IZK7
names: Subcellular Location Annotation
messages: Membrane

2184053:DN051 RS35490
gene id: 2184053:DN051_RS35490
uniprot id: A0A2Z4J852
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2184053:DN051 RS41865
gene id: 2184053:DN051_RS41865
uniprot id: A0A2Z4JDN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2184053:DN051 RS18775
gene id: 2184053:DN051_RS18775
uniprot id: A0A2Z4J0F7
names: Function
names: Similarity
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids lysine, threonine, isoleucine and methionine.

2184053:DN051 RS07875
gene id: 2184053:DN051_RS07875
uniprot id: A0A2Z4IUU6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
messages: Belongs to the azoreductase type 1 family.
messages: Binds 1 FMN per subunit.
messages: Homodimer.
messages: Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones.

2184053:DN051 RS24940
gene id: 2184053:DN051_RS24940
uniprot id: A0A2Z4J2S5
names: Similarity
messages: Belongs to the glycosyl hydrolase 26 family.

2184053:DN051 RS31330
gene id: 2184053:DN051_RS31330
uniprot id: A0A2Z4J5W4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

2184053:DN051 RS28675
gene id: 2184053:DN051_RS28675
uniprot id: A0A2Z4J536
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

2184053:DN051 RS06125
gene id: 2184053:DN051_RS06125
uniprot id: A0A2Z4IU37
names: Similarity
messages: Belongs to the cytochrome P450 family.

2184053:DN051 RS30190
gene id: 2184053:DN051_RS30190
uniprot id: A0A2Z4J6U8
names: Subcellular Location Annotation
messages: Membrane

2184053:DN051 RS22640
gene id: 2184053:DN051_RS22640
uniprot id: A0A2Z4J285
names: Subcellular Location Annotation
messages: Membrane

2184053:DN051 RS18150
gene id: 2184053:DN051_RS18150
uniprot id: A0A2Z4IZU8
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

2184053:DN051 RS14455
gene id: 2184053:DN051_RS14455
uniprot id: A0A2Z4IY12
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: Nucleus
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

2184053:DN051 RS24185
gene id: 2184053:DN051_RS24185
uniprot id: A0A2Z4J2W6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

2184053:DN051 RS27785
gene id: 2184053:DN051_RS27785
uniprot id: A0A2Z4J446
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
messages: Cytoplasm
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Non-allosteric.

2184053:DN051 RS28040
gene id: 2184053:DN051_RS28040
uniprot id: A0A2Z4J4P3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

2184053:DN051 RS08770
gene id: 2184053:DN051_RS08770
uniprot id: A0A2Z4IV13
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit A family.

2184053:DN051 RS25980
gene id: 2184053:DN051_RS25980
uniprot id: A0A2Z4J3W0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of glycine to tRNA(Gly).
messages: Cytoplasm
messages: Homodimer.

2184053:DN051 RS30760
gene id: 2184053:DN051_RS30760
uniprot id: A0A2Z4J7Y8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

2184053:DN051 RS19030
gene id: 2184053:DN051_RS19030
uniprot id: A0A2Z4J223
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

2184053:DN051 RS20790
gene id: 2184053:DN051_RS20790
uniprot id: A0A2Z4J1Q1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

2184053:DN051 RS18555
gene id: 2184053:DN051_RS18555
uniprot id: A0A2Z4J078
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

2184053:DN051 RS16830
gene id: 2184053:DN051_RS16830
uniprot id: A0A2Z4J0X8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

2184053:DN051 RS24090
gene id: 2184053:DN051_RS24090
uniprot id: A0A2Z4J3A1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ClpS family.
messages: Binds to the N-terminal domain of the chaperone ClpA.
messages: Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.

2184053:DN051 RS14600
gene id: 2184053:DN051_RS14600
uniprot id: A0A2Z4IY73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Membrane

2184053:DN051 RS19365
gene id: 2184053:DN051_RS19365
uniprot id: A0A2Z4J1G7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2184053:DN051 RS21940
gene id: 2184053:DN051_RS21940
uniprot id: A0A2Z4J159
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

2184053:DN051 RS10840
gene id: 2184053:DN051_RS10840
uniprot id: A0A2Z4IWA8
names: Subcellular Location Annotation
messages: Membrane

2184053:DN051 RS25935
gene id: 2184053:DN051_RS25935
uniprot id: A0A2Z4J4L7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M7 family.
messages: Secreted

2184053:DN051 RS24900
gene id: 2184053:DN051_RS24900
uniprot id: A0A2Z4J2S2
names: Similarity
messages: Belongs to the TPP enzyme family.

2184053:DN051 RS06910
gene id: 2184053:DN051_RS06910
uniprot id: A0A2Z4IUN0
names: Subcellular Location Annotation
messages: Membrane

2184053:DN051 RS30195
gene id: 2184053:DN051_RS30195
uniprot id: A0A2Z4J5V5
names: Similarity
messages: Belongs to the Nudix hydrolase family.

2184053:DN051 RS03620
gene id: 2184053:DN051_RS03620
uniprot id: A0A2Z4ISZ6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2184053:DN051 RS21495
gene id: 2184053:DN051_RS21495
uniprot id: A0A2Z4J211
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2184053:DN051 RS19375
gene id: 2184053:DN051_RS19375
uniprot id: A0A2Z4J0F4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

2184053:DN051 RS05720
gene id: 2184053:DN051_RS05720
uniprot id: A0A2Z4ITL9
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

2184053:DN051 RS25150
gene id: 2184053:DN051_RS25150
uniprot id: A0A2Z4J3H4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2184053:DN051 RS14180
gene id: 2184053:DN051_RS14180
uniprot id: A0A2Z4IXV4
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

2184053:DN051 RS26625
gene id: 2184053:DN051_RS26625
uniprot id: A0A2Z4J3L6
names: Similarity
messages: Belongs to the group II decarboxylase family.

2184053:DN051 RS18165
gene id: 2184053:DN051_RS18165
uniprot id: A0A2Z4IZN4
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

2184053:DN051 RS03420
gene id: 2184053:DN051_RS03420
uniprot id: A0A2Z4ITF1
names: Similarity
messages: Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family.

2184053:DN051 RS17320
gene id: 2184053:DN051_RS17320
uniprot id: A0A2Z4J015
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

2184053:DN051 RS17315
gene id: 2184053:DN051_RS17315
uniprot id: A0A2Z4IZA4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

2184053:DN051 RS16880
gene id: 2184053:DN051_RS16880
uniprot id: A0A2Z4IZ04
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

2184053:DN051 RS14905
gene id: 2184053:DN051_RS14905
uniprot id: A0A2Z4IXX7
names: Similarity
messages: Belongs to the peptidase S8 family.

2184053:DN051 RS21340
gene id: 2184053:DN051_RS21340
uniprot id: A0A2Z4J1L8
names: Similarity
messages: Belongs to the F420H(2)-dependent quinone reductase family.

2184053:DN051 RS16540
gene id: 2184053:DN051_RS16540
uniprot id: A0A2Z4IYW8
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

2184053:DN051 RS18115
gene id: 2184053:DN051_RS18115
uniprot id: A0A2Z4J049
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

2184053:DN051 RS25280
gene id: 2184053:DN051_RS25280
uniprot id: A0A2Z4J2Z7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

2184053:DN051 RS12295
gene id: 2184053:DN051_RS12295
uniprot id: A0A2Z4IYM2
names: Activity Regulation
names: Caution
names: Domain
names: Function
names: Similarity
messages: Belongs to the GlnD family.
messages: Has four distinct domains: an N-terminal nucleotidyltransferase (NT) domain responsible for UTase activity, a central HD domain that encodes UR activity, and two C-terminal ACT domains that seem to have a role in glutamine sensing.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism.
messages: Uridylyltransferase (UTase) activity is inhibited by glutamine, while glutamine activates uridylyl-removing (UR) activity.

2184053:DN051 RS23345
gene id: 2184053:DN051_RS23345
uniprot id: A0A2Z4J2K9
names: Subcellular Location Annotation
messages: Cell membrane

2184053:DN051 RS11240
gene id: 2184053:DN051_RS11240
uniprot id: A0A2Z4IX23
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Cytoplasm
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the insertion of ferrous iron into coproporphyrin III to form Fe-coproporphyrin III.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2184053:DN051 RS29680
gene id: 2184053:DN051_RS29680
uniprot id: A0A2Z4J6M3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2184053:DN051 RS33700
gene id: 2184053:DN051_RS33700
uniprot id: A0A2Z4J9D9
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

2184053:DN051 RS24035
gene id: 2184053:DN051_RS24035
uniprot id: A0A2Z4J392
names: Cofactor
names: Similarity
messages: Belongs to the 4HPPD family.
messages: Binds 1 Fe cation per subunit.

2184053:DN051 RS17970
gene id: 2184053:DN051_RS17970
uniprot id: A0A2Z4IZS7
names: Similarity
messages: Belongs to the Nth/MutY family.

2184053:DN051 RS34445
gene id: 2184053:DN051_RS34445
uniprot id: A0A2Z4J838
names: Subcellular Location Annotation
messages: Membrane

2184053:DN051 RS15700
gene id: 2184053:DN051_RS15700
uniprot id: A0A2Z4IYA1
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

2184053:DN051 RS09780
gene id: 2184053:DN051_RS09780
uniprot id: A0A2Z4IVI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

2184053:DN051 RS25410
gene id: 2184053:DN051_RS25410
uniprot id: A0A2Z4J3M2
names: Subcellular Location Annotation
messages: Membrane

2184053:DN051 RS04820
gene id: 2184053:DN051_RS04820
uniprot id: A0A2Z4ISF6
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

2184053:DN051 RS08015
gene id: 2184053:DN051_RS08015
uniprot id: A0A2Z4IUY2
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

2184053:DN051 RS21725
gene id: 2184053:DN051_RS21725
uniprot id: A0A2Z4J187
names: Subcellular Location Annotation
messages: Membrane

2184053:DN051 RS25745
gene id: 2184053:DN051_RS25745
uniprot id: A0A2Z4J3L5
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

2184053:DN051 RS30450
gene id: 2184053:DN051_RS30450
uniprot id: A0A2Z4J5U8
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the Pup ligase/Pup deamidase family. Pup-conjugating enzyme subfamily.
messages: Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine.
messages: The reaction mechanism probably proceeds via the activation of Pup by phosphorylation of its C-terminal glutamate, which is then subject to nucleophilic attack by the substrate lysine, resulting in an isopeptide bond and the release of phosphate as a good leaving group.

2184053:DN051 RS26680
gene id: 2184053:DN051_RS26680
uniprot id: A0A2Z4J3M8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GDT1 family.
messages: Membrane

2184053:DN051 RS23475
gene id: 2184053:DN051_RS23475
uniprot id: A0A2Z4J2K4
names: Similarity
messages: Belongs to the cysteine dioxygenase family.

2184053:DN051 RS22795
gene id: 2184053:DN051_RS22795
uniprot id: A0A2Z4J291
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SsgA family.
messages: Cell septum

2184053:DN051 RS23775
gene id: 2184053:DN051_RS23775
uniprot id: A0A2Z4J355
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

2184053:DN051 RS28845
gene id: 2184053:DN051_RS28845
uniprot id: A0A2Z4J4N0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2184053:DN051 RS11915
gene id: 2184053:DN051_RS11915
uniprot id: A0A2Z4IWL3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

2184053:DN051 RS21700
gene id: 2184053:DN051_RS21700
uniprot id: A0A2Z4J1S7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cell surface
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
messages: capsule
messages: cell wall

2184053:DN051 RS06565
gene id: 2184053:DN051_RS06565
uniprot id: A0A2Z4IU10
names: Function
names: Similarity
messages: Belongs to the EgtB family.
messages: Catalyzes the oxidative sulfurization of hercynine (N-alpha,N-alpha,N-alpha-trimethyl-L-histidine) into hercynyl-gamma-L-glutamyl-L-cysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine.

2184053:DN051 RS28115
gene id: 2184053:DN051_RS28115
uniprot id: A0A2Z4J5T2
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

2184053:DN051 RS30645
gene id: 2184053:DN051_RS30645
uniprot id: A0A2Z4J5L5
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

2184053:DN051 RS34790
gene id: 2184053:DN051_RS34790
uniprot id: A0A2Z4J7U5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
messages: Monomer.

2184053:DN051 RS20785
gene id: 2184053:DN051_RS20785
uniprot id: A0A2Z4J0U7
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

2184053:DN051 RS29795
gene id: 2184053:DN051_RS29795
uniprot id: A0A2Z4J5N8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

2184053:DN051 RS26775
gene id: 2184053:DN051_RS26775
uniprot id: A0A2Z4J3R0
names: Subcellular Location Annotation
messages: Membrane

2184053:DN051 RS32750
gene id: 2184053:DN051_RS32750
uniprot id: A0A2Z4J780
names: Subcellular Location Annotation
messages: Membrane

2184053:DN051 RS30020
gene id: 2184053:DN051_RS30020
uniprot id: A0A2Z4J5S8
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

2184053:DN051 RS14790
gene id: 2184053:DN051_RS14790
uniprot id: A0A2Z4IY45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

2184053:DN051 RS24845
gene id: 2184053:DN051_RS24845
uniprot id: A0A2Z4J2R2
names: Similarity
messages: Belongs to the citrate synthase family.

2184053:DN051 RS17045
gene id: 2184053:DN051_RS17045
uniprot id: A0A2Z4IZC2
names: Similarity
messages: Belongs to the UPF0336 family.

2184053:DN051 RS06120
gene id: 2184053:DN051_RS06120
uniprot id: A0A2Z4IUN2
names: Similarity
messages: Belongs to the terpene synthase family.

2184053:DN051 RS27280
gene id: 2184053:DN051_RS27280
uniprot id: A0A2Z4J4H4
names: Similarity
messages: Belongs to the ArsC family.

2184053:DN051 RS26490
gene id: 2184053:DN051_RS26490
uniprot id: A0A2Z4J4W5
names: Similarity
messages: Belongs to the CdaR family.

2184053:DN051 RS06335
gene id: 2184053:DN051_RS06335
uniprot id: A0A2Z4IU74
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

2184053:DN051 RS30800
gene id: 2184053:DN051_RS30800
uniprot id: A0A2Z4J675
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2184053:DN051 RS05430
gene id: 2184053:DN051_RS05430
uniprot id: A0A2Z4ITH2
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. HypB/HupM subfamily.

2184053:DN051 RS28770
gene id: 2184053:DN051_RS28770
uniprot id: A0A2Z4J672
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gluconeogenesis factor family.
messages: Cytoplasm
messages: Required for morphogenesis under gluconeogenic growth conditions.

2184053:DN051 RS25625
gene id: 2184053:DN051_RS25625
uniprot id: A0A2Z4J3J4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 87 family.
messages: Membrane

2184053:DN051 RS17160
gene id: 2184053:DN051_RS17160
uniprot id: A0A2Z4IZ87
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

2184053:DN051 RS28390
gene id: 2184053:DN051_RS28390
uniprot id: A0A2Z4J4V1
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

2184053:DN051 RS24625
gene id: 2184053:DN051_RS24625
uniprot id: A0A2Z4J361
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

2184053:DN051 RS09640
gene id: 2184053:DN051_RS09640
uniprot id: A0A2Z4JB25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

2184053:DN051 RS35680
gene id: 2184053:DN051_RS35680
uniprot id: A0A2Z4J8U9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
messages: Belongs to the azoreductase type 1 family.
messages: Binds 1 FMN per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones.

2184053:DN051 RS30885
gene id: 2184053:DN051_RS30885
uniprot id: A0A2Z4J615
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nlpA lipoprotein family.
messages: Membrane

2184053:DN051 RS04750
gene id: 2184053:DN051_RS04750
uniprot id: A0A2Z4ITM2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2184053:DN051 RS06455
gene id: 2184053:DN051_RS06455
uniprot id: A0A2Z4JB04
names: Similarity
messages: Belongs to the thioredoxin family.

2184053:DN051 RS21620
gene id: 2184053:DN051_RS21620
uniprot id: A0A2Z4J168
names: Similarity
messages: Belongs to the prokaryotic/mitochondrial release factor family.

2184053:DN051 RS32775
gene id: 2184053:DN051_RS32775
uniprot id: A0A2Z4J6U7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2184053:DN051 RS43425
gene id: 2184053:DN051_RS43425
uniprot id: A0A2Z4JE64
names: Similarity
names: Subunit
messages: Belongs to the sigma-70 factor family. ECF subfamily.
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

2184053:DN051 RS24365
gene id: 2184053:DN051_RS24365
uniprot id: A0A2Z4J2I3
names: Similarity
messages: Belongs to the glycosyl hydrolase family 6.

2184053:DN051 RS12445
gene id: 2184053:DN051_RS12445
uniprot id: A0A2Z4IWW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

2184053:DN051 RS09250
gene id: 2184053:DN051_RS09250
uniprot id: A0A2Z4IVA3
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

2184053:DN051 RS05595
gene id: 2184053:DN051_RS05595
uniprot id: A0A2Z4IT79
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2184053:DN051 RS15120
gene id: 2184053:DN051_RS15120
uniprot id: A0A2Z4IY94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

2184053:DN051 RS19945
gene id: 2184053:DN051_RS19945
uniprot id: A0A2Z4J0I1
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

2184053:DN051 RS16565
gene id: 2184053:DN051_RS16565
uniprot id: A0A2Z4IZ12
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2184053:DN051 RS12880
gene id: 2184053:DN051_RS12880
uniprot id: A0A2Z4IXS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

2184053:DN051 RS17305
gene id: 2184053:DN051_RS17305
uniprot id: A0A2Z4J158
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

2184053:DN051 RS13150
gene id: 2184053:DN051_RS13150
uniprot id: A0A2Z4IXJ3
names: Subunit
messages: Heterodimer of an alpha and a beta chain.

2184053:DN051 RS34550
gene id: 2184053:DN051_RS34550
uniprot id: A0A2Z4J7W1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2184053:DN051 RS25160
gene id: 2184053:DN051_RS25160
uniprot id: A0A2Z4J2W1
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

2184053:DN051 RS31310
gene id: 2184053:DN051_RS31310
uniprot id: A0A2Z4J7F1
names: Similarity
messages: Belongs to the universal ribosomal protein uS13 family.

2184053:DN051 RS27715
gene id: 2184053:DN051_RS27715
uniprot id: A0A2Z4J4Q8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 87 family.
messages: Membrane

2184053:DN051 RS11850
gene id: 2184053:DN051_RS11850
uniprot id: A0A2Z4IYD6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

2184053:DN051 RS16985
gene id: 2184053:DN051_RS16985
uniprot id: A0A2Z4IZW2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

2184053:DN051 RS14925
gene id: 2184053:DN051_RS14925
uniprot id: A0A2Z4IYA4
names: Similarity
messages: Belongs to the cytochrome P450 family.

2184053:DN051 RS19910
gene id: 2184053:DN051_RS19910
uniprot id: A0A2Z4J0F3
names: Similarity
messages: Belongs to the FemABX family.

2184053:DN051 RS26225
gene id: 2184053:DN051_RS26225
uniprot id: A0A2Z4J411
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterotetramer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits of ACCase subunit beta/alpha.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the AccA family.
messages: In the N-terminal section; belongs to the AccD/PCCB family.

2184053:DN051 RS10370
gene id: 2184053:DN051_RS10370
uniprot id: A0A2Z4IWN6
names: Subcellular Location Annotation
messages: Membrane

2184053:DN051 RS22990
gene id: 2184053:DN051_RS22990
uniprot id: A0A2Z4J206
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

2184053:DN051 RS14705
gene id: 2184053:DN051_RS14705
uniprot id: A0A2Z4IY61
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

2184053:DN051 RS27400
gene id: 2184053:DN051_RS27400
uniprot id: A0A2Z4J3X5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glutamine synthetase family.
messages: Cytoplasm
messages: Oligomer of 12 subunits arranged in the form of two hexagons.

2184053:DN051 RS11475
gene id: 2184053:DN051_RS11475
uniprot id: A0A2Z4IVQ4
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

2184053:DN051 RS27650
gene id: 2184053:DN051_RS27650
uniprot id: A0A2Z4J4X8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

2184053:DN051 RS10825
gene id: 2184053:DN051_RS10825
uniprot id: A0A2Z4IWC1
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

2184053:DN051 RS12975
gene id: 2184053:DN051_RS12975
uniprot id: A0A2Z4IXC6
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

2184053:DN051 RS12305
gene id: 2184053:DN051_RS12305
uniprot id: A0A2Z4IWS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

2184053:DN051 RS25270
gene id: 2184053:DN051_RS25270
uniprot id: A0A2Z4J5F6
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

2184053:DN051 RS09360
gene id: 2184053:DN051_RS09360
uniprot id: A0A2Z4IVK3
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

2184053:DN051 RS06375
gene id: 2184053:DN051_RS06375
uniprot id: A0A2Z4IT63
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

2184053:DN051 RS25530
gene id: 2184053:DN051_RS25530
uniprot id: A0A2Z4J3P1
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

2184053:DN051 RS08420
gene id: 2184053:DN051_RS08420
uniprot id: A0A2Z4IUN7
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

2184053:DN051 RS15470
gene id: 2184053:DN051_RS15470
uniprot id: A0A2Z4IZ93
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

2184053:DN051 RS24960
gene id: 2184053:DN051_RS24960
uniprot id: A0A2Z4J3P0
names: Subcellular Location Annotation
messages: Membrane

2184053:DN051 RS15820
gene id: 2184053:DN051_RS15820
uniprot id: A0A2Z4IYI2
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

2184053:DN051 RS34660
gene id: 2184053:DN051_RS34660
uniprot id: A0A2Z4J876
names: Similarity
messages: Belongs to the glycosyl hydrolase 27 family.

2184053:DN051 RS16835
gene id: 2184053:DN051_RS16835
uniprot id: A0A2Z4IZI4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

2184053:DN051 RS03380
gene id: 2184053:DN051_RS03380
uniprot id: A0A2Z4IT12
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

2184053:DN051 RS24585
gene id: 2184053:DN051_RS24585
uniprot id: A0A2Z4J2Y2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-to-5' exoribonuclease specific for small oligoribonucleotides.
messages: Belongs to the oligoribonuclease family.
messages: Cytoplasm

2184053:DN051 RS09335
gene id: 2184053:DN051_RS09335
uniprot id: A0A2Z4IVR8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2184053:DN051 RS21395
gene id: 2184053:DN051_RS21395
uniprot id: A0A2Z4J0X7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyltransferase group 1 family. MshA subfamily.
messages: Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2-acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway.
messages: Homodimer.

2184053:DN051 RS36010
gene id: 2184053:DN051_RS36010
uniprot id: A0A2Z4J8M5
names: Similarity
messages: Belongs to the glycosyl hydrolase 130 family.

2184053:DN051 RS13355
gene id: 2184053:DN051_RS13355
uniprot id: A0A2Z4IXJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

2184053:DN051 RS22810
gene id: 2184053:DN051_RS22810
uniprot id: A0A2Z4J2C0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 39 family.
messages: Cell membrane
messages: Membrane
messages: Transfers mannose from Dol-P-mannose to Ser or Thr residues on proteins.

2184053:DN051 RS05675
gene id: 2184053:DN051_RS05675
uniprot id: A0A2Z4ITV8
names: Subcellular Location Annotation
messages: Membrane

2184053:DN051 RS18460
gene id: 2184053:DN051_RS18460
uniprot id: A0A2Z4J0B0
names: Subcellular Location Annotation
messages: Membrane

2184053:DN051 RS26125
gene id: 2184053:DN051_RS26125
uniprot id: A0A2Z4J5V8
names: Similarity
messages: Belongs to the dGTPase family. Type 2 subfamily.

2184053:DN051 RS16060
gene id: 2184053:DN051_RS16060
uniprot id: A0A2Z4IZF1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

2184053:DN051 RS19765
gene id: 2184053:DN051_RS19765
uniprot id: A0A2Z4J1P9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

2184053:DN051 RS27190
gene id: 2184053:DN051_RS27190
uniprot id: A0A2Z4J6B0
names: Similarity
messages: Belongs to the bacterial solute-binding protein 1 family.

2184053:DN051 RS31810
gene id: 2184053:DN051_RS31810
uniprot id: A0A2Z4J7Q3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

2184053:DN051 RS24465
gene id: 2184053:DN051_RS24465
uniprot id: A0A2Z4J350
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

2184053:DN051 RS12265
gene id: 2184053:DN051_RS12265
uniprot id: A0A2Z4IWZ2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

2184053:DN051 RS09615
gene id: 2184053:DN051_RS09615
uniprot id: A0A2Z4IVF7
names: Subunit
messages: Heterodimer of an alpha and a beta chain.

2184053:DN051 RS17640
gene id: 2184053:DN051_RS17640
uniprot id: A0A2Z4IZ77
names: Similarity
messages: Belongs to the AHA1 family.

2184053:DN051 RS10695
gene id: 2184053:DN051_RS10695
uniprot id: A0A2Z4IW01
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Catalyzes the reversible hydration of carbon dioxide to form bicarbonate.
messages: Reversible hydration of carbon dioxide.

2184053:DN051 RS31855
gene id: 2184053:DN051_RS31855
uniprot id: A0A2Z4J6G5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sbp family.
messages: Cell membrane

2184053:DN051 RS05330
gene id: 2184053:DN051_RS05330
uniprot id: A0A2Z4JC33
names: Similarity
messages: Belongs to the amidinotransferase family.

2184053:DN051 RS15230
gene id: 2184053:DN051_RS15230
uniprot id: A0A2Z4IZ05
names: Subcellular Location Annotation
messages: Membrane

2184053:DN051 RS15115
gene id: 2184053:DN051_RS15115
uniprot id: A0A2Z4IYF4
names: Function
names: Similarity
names: Subunit
messages: Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity.
messages: Belongs to the AhpD family.
messages: Homotrimer.

2184053:DN051 RS08580
gene id: 2184053:DN051_RS08580
uniprot id: A0A2Z4IUA6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IPP isomerase type 1 family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium ion binds only when substrate is bound.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).
messages: Cytoplasm

2184053:DN051 RS18940
gene id: 2184053:DN051_RS18940
uniprot id: A0A2Z4J002
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2184053:DN051 RS23535
gene id: 2184053:DN051_RS23535
uniprot id: A0A2Z4J242
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

2184053:DN051 RS28870
gene id: 2184053:DN051_RS28870
uniprot id: A0A2Z4J5G4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 2 subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

2184053:DN051 RS11680
gene id: 2184053:DN051_RS11680
uniprot id: A0A2Z4IWP9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

2184053:DN051 RS09390
gene id: 2184053:DN051_RS09390
uniprot id: A0A2Z4IVI8
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

2184053:DN051 RS13695
gene id: 2184053:DN051_RS13695
uniprot id: A0A2Z4IXR4
names: Similarity
messages: Belongs to the cytochrome P450 family.

2184053:DN051 RS16970
gene id: 2184053:DN051_RS16970
uniprot id: A0A2Z4IZK2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

2184053:DN051 RS30715
gene id: 2184053:DN051_RS30715
uniprot id: A0A2Z4J5M6
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

2184053:DN051 RS14745
gene id: 2184053:DN051_RS14745
uniprot id: A0A2Z4JB58
names: Similarity
messages: Belongs to the UPF0162 family.

2184053:DN051 RS42295
gene id: 2184053:DN051_RS42295
uniprot id: A0A2Z4JDV8
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

2184053:DN051 RS23385
gene id: 2184053:DN051_RS23385
uniprot id: A0A2Z4J3E6
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

2184053:DN051 RS14975
gene id: 2184053:DN051_RS14975
uniprot id: A0A2Z4IYD4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

2184053:DN051 RS22325
gene id: 2184053:DN051_RS22325
uniprot id: A0A2Z4J1C0
names: Similarity
messages: Belongs to the F420H(2)-dependent quinone reductase family.

2184053:DN051 RS36390
gene id: 2184053:DN051_RS36390
uniprot id: A0A2Z4J8W3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2184053:DN051 RS22545
gene id: 2184053:DN051_RS22545
uniprot id: A0A2Z4J1P7
names: Subcellular Location Annotation
messages: Membrane

2184053:DN051 RS18720
gene id: 2184053:DN051_RS18720
uniprot id: A0A2Z4IZW1
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

2184053:DN051 RS24140
gene id: 2184053:DN051_RS24140
uniprot id: A0A2Z4J3B1
names: Subcellular Location Annotation
messages: Membrane

2184053:DN051 RS31670
gene id: 2184053:DN051_RS31670
uniprot id: A0A2Z4J6D4
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

2184053:DN051 RS23700
gene id: 2184053:DN051_RS23700
uniprot id: A0A2Z4J4L1
names: Similarity
messages: Belongs to the OsmC/Ohr family.

2184053:DN051 RS26220
gene id: 2184053:DN051_RS26220
uniprot id: A0A2Z4J4A1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2184053:DN051 RS22840
gene id: 2184053:DN051_RS22840
uniprot id: A0A2Z4J1U1
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

2184053:DN051 RS28055
gene id: 2184053:DN051_RS28055
uniprot id: A0A2Z4J4X1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

2184053:DN051 RS12465
gene id: 2184053:DN051_RS12465
uniprot id: A0A2Z4IXM6
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

2184053:DN051 RS11245
gene id: 2184053:DN051_RS11245
uniprot id: A0A2Z4IWH4
names: Subcellular Location Annotation
messages: Membrane

2184053:DN051 RS17890
gene id: 2184053:DN051_RS17890
uniprot id: A0A2Z4J005
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

2184053:DN051 RS08130
gene id: 2184053:DN051_RS08130
uniprot id: A0A2Z4IUZ6
names: Similarity
messages: Belongs to the group II decarboxylase family.

2184053:DN051 RS06200
gene id: 2184053:DN051_RS06200
uniprot id: A0A2Z4IT35
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

2184053:DN051 RS28375
gene id: 2184053:DN051_RS28375
uniprot id: A0A2Z4JD75
names: Similarity
messages: Belongs to the peptidase M1 family.

2184053:DN051 RS08815
gene id: 2184053:DN051_RS08815
uniprot id: A0A2Z4IX02
names: Function
names: Similarity
messages: Belongs to the anhydro-N-acetylmuramic acid kinase family.
messages: Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.

2184053:DN051 RS05385
gene id: 2184053:DN051_RS05385
uniprot id: A0A2Z4IUB2
names: Similarity
names: Subunit
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase small subunit family.
messages: Heterodimer of a large and a small subunit.

2184053:DN051 RS31675
gene id: 2184053:DN051_RS31675
uniprot id: A0A2Z4J647
names: Subcellular Location Annotation
messages: Membrane

2184053:DN051 RS12915
gene id: 2184053:DN051_RS12915
uniprot id: A0A2Z4IX34
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

2184053:DN051 RS31465
gene id: 2184053:DN051_RS31465
uniprot id: A0A2Z4J6N7
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Feedback inhibited by histidine.

2184053:DN051 RS02010
gene id: 2184053:DN051_RS02010
uniprot id: A0A2Z4ISF0
names: Subcellular Location Annotation
messages: Cytoplasm

2184053:DN051 RS23680
gene id: 2184053:DN051_RS23680
uniprot id: A0A2Z4J2S3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

2184053:DN051 RS16895
gene id: 2184053:DN051_RS16895
uniprot id: A0A2Z4IZ53
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

2184053:DN051 RS22915
gene id: 2184053:DN051_RS22915
uniprot id: A0A2Z4J1U3
names: Subcellular Location Annotation
messages: Membrane

2184053:DN051 RS31580
gene id: 2184053:DN051_RS31580
uniprot id: A0A2Z4J7K8
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

2184053:DN051 RS17025
gene id: 2184053:DN051_RS17025
uniprot id: A0A2Z4J112
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

2184053:DN051 RS08810
gene id: 2184053:DN051_RS08810
uniprot id: A0A2Z4IV17
names: Subcellular Location Annotation
messages: Membrane

2184053:DN051 RS03980
gene id: 2184053:DN051_RS03980
uniprot id: A0A2Z4IS07
names: Similarity
messages: Belongs to the heat shock protein 90 family.

2184053:DN051 RS41375
gene id: 2184053:DN051_RS41375
uniprot id: A0A2Z4JDF3
names: Subcellular Location Annotation
messages: Membrane

2184053:DN051 RS12420
gene id: 2184053:DN051_RS12420
uniprot id: A0A2Z4IX22
names: Function
messages: Catalyzes the phosphorylation of hydroxymethylpyrimidine phosphate (HMP-P) to HMP-PP, and of HMP to HMP-P.

2184053:DN051 RS22025
gene id: 2184053:DN051_RS22025
uniprot id: A0A2Z4J1T1
names: Similarity
messages: Belongs to the citrate synthase family.

2184053:DN051 RS34980
gene id: 2184053:DN051_RS34980
uniprot id: A0A2Z4J7Q4
names: Subcellular Location Annotation
messages: Membrane

2184053:DN051 RS16915
gene id: 2184053:DN051_RS16915
uniprot id: A0A2Z4IZV9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

2184053:DN051 RS27990
gene id: 2184053:DN051_RS27990
uniprot id: A0A2Z4J521
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsQ/DivIB family. FtsQ subfamily.
messages: Cell membrane
messages: Essential cell division protein.

2184053:DN051 RS06560
gene id: 2184053:DN051_RS06560
uniprot id: A0A2Z4IUB8
names: Function
names: Similarity
messages: Belongs to the glutamate--cysteine ligase type 2 family. EgtA subfamily.
messages: Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC). This compound is used as substrate for the biosynthesis of the low-molecular thiol compound ergothioneine.

2184053:DN051 RS11895
gene id: 2184053:DN051_RS11895
uniprot id: A0A2Z4IVX5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

2184053:DN051 RS09420
gene id: 2184053:DN051_RS09420
uniprot id: A0A2Z4IW96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

2184053:DN051 RS24425
gene id: 2184053:DN051_RS24425
uniprot id: A0A2Z4J2J2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

2184053:DN051 RS28795
gene id: 2184053:DN051_RS28795
uniprot id: A0A2Z4J704
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

2184053:DN051 RS33160
gene id: 2184053:DN051_RS33160
uniprot id: A0A2Z4J8B5
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

2184053:DN051 RS31145
gene id: 2184053:DN051_RS31145
uniprot id: A0A2Z4J5V0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

2184053:DN051 RS16825
gene id: 2184053:DN051_RS16825
uniprot id: A0A2Z4JBJ5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

2184053:DN051 RS14690
gene id: 2184053:DN051_RS14690
uniprot id: A0A2Z4IZX3
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

2184053:DN051 RS31125
gene id: 2184053:DN051_RS31125
uniprot id: A0A2Z4J5W3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RuvC family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.

2184053:DN051 RS15400
gene id: 2184053:DN051_RS15400
uniprot id: A0A2Z4IZ28
names: Subcellular Location Annotation
messages: Membrane

2184053:DN051 RS25400
gene id: 2184053:DN051_RS25400
uniprot id: A0A2Z4J315
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Membrane

2184053:DN051 RS08405
gene id: 2184053:DN051_RS08405
uniprot id: A0A2Z4IVA7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA.
messages: Homodimer.

2184053:DN051 RS29210
gene id: 2184053:DN051_RS29210
uniprot id: A0A2Z4J4Y0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

2184053:DN051 RS15770
gene id: 2184053:DN051_RS15770
uniprot id: A0A2Z4J0D5
names: Similarity
messages: Belongs to the adenylyl cyclase class-3 family.

2184053:DN051 RS23905
gene id: 2184053:DN051_RS23905
uniprot id: A0A2Z4J4P8
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

2184053:DN051 RS15935
gene id: 2184053:DN051_RS15935
uniprot id: A0A2Z4J0H3
names: Subcellular Location Annotation
messages: Membrane

2184053:DN051 RS28265
gene id: 2184053:DN051_RS28265
uniprot id: A0A2Z4J4G6
names: Subcellular Location Annotation
messages: Membrane

2184053:DN051 RS24545
gene id: 2184053:DN051_RS24545
uniprot id: A0A2Z4J2L1
names: Subcellular Location Annotation
messages: Cell membrane

2184053:DN051 RS34735
gene id: 2184053:DN051_RS34735
uniprot id: A0A2Z4J7T6
names: Subcellular Location Annotation
messages: Membrane

2184053:DN051 RS28000
gene id: 2184053:DN051_RS28000
uniprot id: A0A2Z4J5R6
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

2184053:DN051 RS28710
gene id: 2184053:DN051_RS28710
uniprot id: A0A2Z4J5D2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

2184053:DN051 RS08510
gene id: 2184053:DN051_RS08510
uniprot id: A0A2Z4IVC7
names: Similarity
messages: Belongs to the terpene cyclase/mutase family.

2184053:DN051 RS29470
gene id: 2184053:DN051_RS29470
uniprot id: A0A2Z4J539
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

2184053:DN051 RS16785
gene id: 2184053:DN051_RS16785
uniprot id: A0A2Z4IZ36
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

2184053:DN051 RS26900
gene id: 2184053:DN051_RS26900
uniprot id: A0A2Z4J571
names: Similarity
messages: Belongs to the UPF0246 family.

2184053:DN051 RS24705
gene id: 2184053:DN051_RS24705
uniprot id: A0A2Z4J555
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

2184053:DN051 RS34820
gene id: 2184053:DN051_RS34820
uniprot id: A0A2Z4J8B0
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

2184053:DN051 RS05255
gene id: 2184053:DN051_RS05255
uniprot id: A0A2Z4IU23
names: Subcellular Location Annotation
messages: Membrane

2184053:DN051 RS26535
gene id: 2184053:DN051_RS26535
uniprot id: A0A2Z4J470
names: Subcellular Location Annotation
messages: Membrane

2184053:DN051 RS17780
gene id: 2184053:DN051_RS17780
uniprot id: A0A2Z4J0G6
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

2184053:DN051 RS17310
gene id: 2184053:DN051_RS17310
uniprot id: A0A2Z4IZR4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

2184053:DN051 RS32520
gene id: 2184053:DN051_RS32520
uniprot id: A0A2Z4J814
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

2184053:DN051 RS31155
gene id: 2184053:DN051_RS31155
uniprot id: A0A2Z4J6I0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

2184053:DN051 RS31910
gene id: 2184053:DN051_RS31910
uniprot id: A0A2Z4J684
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

2184053:DN051 RS23870
gene id: 2184053:DN051_RS23870
uniprot id: A0A2Z4J2T0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
messages: Membrane

2184053:DN051 RS23715
gene id: 2184053:DN051_RS23715
uniprot id: A0A2Z4J345
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2184053:DN051 RS18525
gene id: 2184053:DN051_RS18525
uniprot id: A0A2Z4IZJ9
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

2184053:DN051 RS18545
gene id: 2184053:DN051_RS18545
uniprot id: A0A2Z4IZT5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Catalyzes the reversible hydration of carbon dioxide to form bicarbonate.
messages: Membrane

2184053:DN051 RS18110
gene id: 2184053:DN051_RS18110
uniprot id: A0A2Z4J1L1
names: Subcellular Location Annotation
messages: Mitochondrion

2184053:DN051 RS14150
gene id: 2184053:DN051_RS14150
uniprot id: A0A2Z4IXZ2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

2184053:DN051 RS25550
gene id: 2184053:DN051_RS25550
uniprot id: A0A2Z4J305
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

2184053:DN051 RS18290
gene id: 2184053:DN051_RS18290
uniprot id: A0A2Z4IZQ1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

2184053:DN051 RS14645
gene id: 2184053:DN051_RS14645
uniprot id: A0A2Z4IYR4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.
messages: In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: In the N-terminal section; belongs to the MIP18 family.

2184053:DN051 RS19380
gene id: 2184053:DN051_RS19380
uniprot id: A0A2Z4IZZ3
names: Similarity
messages: Belongs to the pirin family.

2184053:DN051 RS11040
gene id: 2184053:DN051_RS11040
uniprot id: A0A2Z4IWA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arginine deiminase family.
messages: Cytoplasm

2184053:DN051 RS10240
gene id: 2184053:DN051_RS10240
uniprot id: A0A2Z4IVS4
names: Similarity
messages: Belongs to the TPP enzyme family.

2184053:DN051 RS24725
gene id: 2184053:DN051_RS24725
uniprot id: A0A2Z4J2P2
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.

2184053:DN051 RS10200
gene id: 2184053:DN051_RS10200
uniprot id: A0A2Z4IVR1
names: Similarity
messages: Belongs to the CdaR family.

2184053:DN051 RS22785
gene id: 2184053:DN051_RS22785
uniprot id: A0A2Z4J1T2
names: Subcellular Location Annotation
messages: Membrane

2184053:DN051 RS22920
gene id: 2184053:DN051_RS22920
uniprot id: A0A2Z4J2Q0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PEPCase type 1 family.
messages: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
messages: Homotetramer.

2184053:DN051 RS30740
gene id: 2184053:DN051_RS30740
uniprot id: A0A2Z4J636
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

2184053:DN051 RS11855
gene id: 2184053:DN051_RS11855
uniprot id: A0A2Z4IWW7
names: Similarity
messages: Belongs to the peptidase M16 family.

2184053:DN051 RS09105
gene id: 2184053:DN051_RS09105
uniprot id: A0A2Z4IVG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2184053:DN051 RS06300
gene id: 2184053:DN051_RS06300
uniprot id: A0A2Z4IUK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2184053:DN051 RS12925
gene id: 2184053:DN051_RS12925
uniprot id: A0A2Z4IXB7
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

2184053:DN051 RS13285
gene id: 2184053:DN051_RS13285
uniprot id: A0A2Z4IXK4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NucS endonuclease family.
messages: Cleaves both 3' and 5' ssDNA extremities of branched DNA structures.
messages: Cytoplasm

2184053:DN051 RS08705
gene id: 2184053:DN051_RS08705
uniprot id: A0A2Z4IV89
names: Similarity
messages: Belongs to the DDAH family.

2184053:DN051 RS12245
gene id: 2184053:DN051_RS12245
uniprot id: A0A2Z4IYL1
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

2184053:DN051 RS25755
gene id: 2184053:DN051_RS25755
uniprot id: A0A2Z4J412
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

2184053:DN051 RS12715
gene id: 2184053:DN051_RS12715
uniprot id: A0A2Z4IXQ1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

2184053:DN051 RS24100
gene id: 2184053:DN051_RS24100
uniprot id: A0A2Z4J3Q8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family.
messages: Membrane

2184053:DN051 RS30900
gene id: 2184053:DN051_RS30900
uniprot id: A0A2Z4J6D3
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

2184053:DN051 RS28105
gene id: 2184053:DN051_RS28105
uniprot id: A0A2Z4J541
names: Subcellular Location Annotation
messages: Membrane

2184053:DN051 RS09655
gene id: 2184053:DN051_RS09655
uniprot id: A0A2Z4IVH4
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

2184053:DN051 RS30230
gene id: 2184053:DN051_RS30230
uniprot id: A0A2Z4J620
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2184053:DN051 RS25275
gene id: 2184053:DN051_RS25275
uniprot id: A0A2Z4J3D9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family.
messages: Membrane

2184053:DN051 RS13425
gene id: 2184053:DN051_RS13425
uniprot id: A0A2Z4IX13
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2184053:DN051 RS21910
gene id: 2184053:DN051_RS21910
uniprot id: A0A2Z4J1B3
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

2184053:DN051 RS12135
gene id: 2184053:DN051_RS12135
uniprot id: A0A2Z4IX10
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

2184053:DN051 RS22345
gene id: 2184053:DN051_RS22345
uniprot id: A0A2Z4J1I4
names: Function
names: Similarity
messages: Catalyzes the radical-mediated synthesis of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (FO) from 5-amino-6-(D-ribitylamino)uracil and L-tyrosine.
messages: In the C-terminal section; belongs to the radical SAM superfamily. CofH family.
messages: In the N-terminal section; belongs to the radical SAM superfamily. CofG family.

2184053:DN051 RS19920
gene id: 2184053:DN051_RS19920
uniprot id: A0A2Z4J0X0
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

2184053:DN051 RS16920
gene id: 2184053:DN051_RS16920
uniprot id: A0A2Z4IZ73
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

2184053:DN051 RS26480
gene id: 2184053:DN051_RS26480
uniprot id: A0A2Z4J4E3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

2184053:DN051 RS13225
gene id: 2184053:DN051_RS13225
uniprot id: A0A2Z4IXJ8
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

2184053:DN051 RS22780
gene id: 2184053:DN051_RS22780
uniprot id: A0A2Z4J1K2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Part of an ABC transporter complex. Responsible for energy coupling to the transport system.

2184053:DN051 RS12425
gene id: 2184053:DN051_RS12425
uniprot id: A0A2Z4IXK8
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

2184053:DN051 RS19930
gene id: 2184053:DN051_RS19930
uniprot id: A0A2Z4J0P0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

2184053:DN051 RS30345
gene id: 2184053:DN051_RS30345
uniprot id: A0A2Z4J634
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

2184053:DN051 RS16790
gene id: 2184053:DN051_RS16790
uniprot id: A0A2Z4IZT1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

2184053:DN051 RS32120
gene id: 2184053:DN051_RS32120
uniprot id: A0A2Z4J8N0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

2184053:DN051 RS36710
gene id: 2184053:DN051_RS36710
uniprot id: A0A2Z4J952
names: Subcellular Location Annotation
messages: Cytoplasm

2184053:DN051 RS25560
gene id: 2184053:DN051_RS25560
uniprot id: A0A2Z4J5L1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

2184053:DN051 RS24605
gene id: 2184053:DN051_RS24605
uniprot id: A0A2Z4J534
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetate uptake transporter (AceTr) (TC 2.A.96) family.
messages: Membrane

2184053:DN051 RS22355
gene id: 2184053:DN051_RS22355
uniprot id: A0A2Z4J1Y4
names: Subcellular Location Annotation
messages: Membrane

2184053:DN051 RS03705
gene id: 2184053:DN051_RS03705
uniprot id: A0A2Z4ISP7
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

2184053:DN051 RS18710
gene id: 2184053:DN051_RS18710
uniprot id: A0A2Z4J1W1
names: Subcellular Location Annotation
messages: Membrane

2184053:DN051 RS31345
gene id: 2184053:DN051_RS31345
uniprot id: A0A2Z4J669
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

2184053:DN051 RS13365
gene id: 2184053:DN051_RS13365
uniprot id: A0A2Z4IXL9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

2184053:DN051 RS27830
gene id: 2184053:DN051_RS27830
uniprot id: A0A2Z4J4Q7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AP endonuclease 2 family.
messages: Binds 3 Zn(2+) ions.
messages: Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.

2184053:DN051 RS12075
gene id: 2184053:DN051_RS12075
uniprot id: A0A2Z4IYI0
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

2184053:DN051 RS06520
gene id: 2184053:DN051_RS06520
uniprot id: A0A2Z4IUA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

2184053:DN051 RS11250
gene id: 2184053:DN051_RS11250
uniprot id: A0A2Z4IX26
names: Similarity
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.

2184053:DN051 RS17725
gene id: 2184053:DN051_RS17725
uniprot id: A0A2Z4IZN2
names: Cofactor
names: Similarity
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.

2184053:DN051 RS31425
gene id: 2184053:DN051_RS31425
uniprot id: A0A2Z4J6H9
names: Subcellular Location Annotation
messages: Membrane

2184053:DN051 RS17285
gene id: 2184053:DN051_RS17285
uniprot id: A0A2Z4IZF6
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

2184053:DN051 RS16545
gene id: 2184053:DN051_RS16545
uniprot id: A0A2Z4IYQ9
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

2184053:DN051 RS17690
gene id: 2184053:DN051_RS17690
uniprot id: A0A2Z4IZ84
names: Subcellular Location Annotation
messages: Cell membrane

2184053:DN051 RS16910
gene id: 2184053:DN051_RS16910
uniprot id: A0A2Z4IZA9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

2184053:DN051 RS13155
gene id: 2184053:DN051_RS13155
uniprot id: A0A2Z4IX86
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

2184053:DN051 RS04970
gene id: 2184053:DN051_RS04970
uniprot id: A0A2Z4ITJ6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

2184053:DN051 RS21735
gene id: 2184053:DN051_RS21735
uniprot id: A0A2Z4J1N5
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A lyase-type mechanism (elimination/hydration) is suggested for the cleavage of the lactyl ether bond of MurNAc 6-phosphate, with the formation of an alpha,beta-unsaturated aldehyde intermediate with (E)-stereochemistry, followed by the syn addition of water to give product.
messages: Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.
messages: Homodimer.
messages: Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate.

2184053:DN051 RS25145
gene id: 2184053:DN051_RS25145
uniprot id: A0A2Z4J384
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2184053:DN051 RS19775
gene id: 2184053:DN051_RS19775
uniprot id: A0A2Z4J0M6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

2184053:DN051 RS17715
gene id: 2184053:DN051_RS17715
uniprot id: A0A2Z4IZF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0060 family.
messages: Cell membrane

2184053:DN051 RS33575
gene id: 2184053:DN051_RS33575
uniprot id: A0A2Z4J7Q0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Heterodimer of an alpha and a beta subunit.
messages: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

2184053:DN051 RS16905
gene id: 2184053:DN051_RS16905
uniprot id: A0A2Z4IZV3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

2184053:DN051 RS17590
gene id: 2184053:DN051_RS17590
uniprot id: A0A2Z4IZD0
names: Caution
names: Function
names: Similarity
messages: Belongs to the UbiX/PAD1 family.
messages: Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2184053:DN051 RS34245
gene id: 2184053:DN051_RS34245
uniprot id: A0A2Z4J7J8
names: Similarity
messages: Belongs to the LacAB/RpiB family.

2184053:DN051 RS41490
gene id: 2184053:DN051_RS41490
uniprot id: A0A2Z4JD85
names: Similarity
messages: Belongs to the FAD-binding monooxygenase family.

2184053:DN051 RS28015
gene id: 2184053:DN051_RS28015
uniprot id: A0A2Z4J490
names: Similarity
messages: Belongs to the YggT family.

2184053:DN051 RS20755
gene id: 2184053:DN051_RS20755
uniprot id: A0A2Z4J0N5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

2184053:DN051 RS05555
gene id: 2184053:DN051_RS05555
uniprot id: A0A2Z4ITS9
names: Subcellular Location Annotation
messages: Cytoplasm

2184053:DN051 RS19690
gene id: 2184053:DN051_RS19690
uniprot id: A0A2Z4J0C0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrgA family.
messages: Cell membrane
messages: Involved in cell division.

2184053:DN051 RS31120
gene id: 2184053:DN051_RS31120
uniprot id: A0A2Z4J6C6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

2184053:DN051 RS30460
gene id: 2184053:DN051_RS30460
uniprot id: A0A2Z4J648
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

2184053:DN051 RS10065
gene id: 2184053:DN051_RS10065
uniprot id: A0A2Z4IXK2
names: Function
names: Similarity
messages: Belongs to the uricase family.
messages: Catalyzes the oxidation of uric acid to 5-hydroxyisourate, which is further processed to form (S)-allantoin.

2184053:DN051 RS28165
gene id: 2184053:DN051_RS28165
uniprot id: A0A2Z4JBU3
names: Subcellular Location Annotation
messages: Membrane

2184053:DN051 RS10850
gene id: 2184053:DN051_RS10850
uniprot id: A0A2Z4IWE2
names: Subcellular Location Annotation
messages: Membrane

2184053:DN051 RS29820
gene id: 2184053:DN051_RS29820
uniprot id: A0A2Z4J7I3
names: Similarity
messages: Belongs to the transglycosylase family. Rpf subfamily.

2184053:DN051 RS20025
gene id: 2184053:DN051_RS20025
uniprot id: A0A2Z4J0Y7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SsgA family.
messages: Cell septum

2184053:DN051 RS12440
gene id: 2184053:DN051_RS12440
uniprot id: A0A2Z4IWA9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

2184053:DN051 RS06010
gene id: 2184053:DN051_RS06010
uniprot id: A0A2Z4ITS0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the protease inhibitor I16 (SSI) family.
messages: Homodimer.
messages: Secreted
messages: Strong inhibitor of bacterial serine proteases such as subtilisin.

2184053:DN051 RS12835
gene id: 2184053:DN051_RS12835
uniprot id: A0A2Z4IXE1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2184053:DN051 RS16190
gene id: 2184053:DN051_RS16190
uniprot id: A0A2Z4JBX4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2184053:DN051 RS31755
gene id: 2184053:DN051_RS31755
uniprot id: A0A2Z4J7N8
names: Activity Regulation
names: Caution
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2184053:DN051 RS26800
gene id: 2184053:DN051_RS26800
uniprot id: A0A2Z4J4A5
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

2184053:DN051 RS30075
gene id: 2184053:DN051_RS30075
uniprot id: A0A2Z4J5X5
names: Subcellular Location Annotation
messages: Membrane

2184053:DN051 RS28785
gene id: 2184053:DN051_RS28785
uniprot id: A0A2Z4J4L9
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

2184053:DN051 RS30485
gene id: 2184053:DN051_RS30485
uniprot id: A0A2Z4J5L9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

2184053:DN051 RS12645
gene id: 2184053:DN051_RS12645
uniprot id: A0A2Z4IWY0
names: Cofactor
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
messages: Binds 2 nickel ions per subunit.
messages: Carbamylation allows a single lysine to coordinate two nickel ions.
messages: Carboxylation allows a single lysine to coordinate two nickel ions.
messages: Cytoplasm
messages: May form a heterohexamer of 3 UreC (alpha) and 3 UreAB (gamma/beta) subunits. May also form a heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

2184053:DN051 RS33570
gene id: 2184053:DN051_RS33570
uniprot id: A0A2Z4J7D9
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta subunit.
messages: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

2184053:DN051 RS30185
gene id: 2184053:DN051_RS30185
uniprot id: A0A2Z4JC72
names: Subcellular Location Annotation
messages: Membrane

2184053:DN051 RS16300
gene id: 2184053:DN051_RS16300
uniprot id: A0A2Z4IYX0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

2184053:DN051 RS24160
gene id: 2184053:DN051_RS24160
uniprot id: A0A2Z4J302
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

2184053:DN051 RS12225
gene id: 2184053:DN051_RS12225
uniprot id: A0A2Z4IX31
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

2184053:DN051 RS18795
gene id: 2184053:DN051_RS18795
uniprot id: A0A2Z4J0Y1
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

2184053:DN051 RS10870
gene id: 2184053:DN051_RS10870
uniprot id: A0A2Z4IXX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2184053:DN051 RS21080
gene id: 2184053:DN051_RS21080
uniprot id: A0A2Z4J1E2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

2184053:DN051 RS31320
gene id: 2184053:DN051_RS31320
uniprot id: A0A2Z4J6G1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

2184053:DN051 RS29530
gene id: 2184053:DN051_RS29530
uniprot id: A0A2Z4J7D4
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

2184053:DN051 RS14710
gene id: 2184053:DN051_RS14710
uniprot id: A0A2Z4IYT6
names: Similarity
messages: Belongs to the LOG family.

2184053:DN051 RS41615
gene id: 2184053:DN051_RS41615
uniprot id: A0A2Z4JDJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2184053:DN051 RS21500
gene id: 2184053:DN051_RS21500
uniprot id: A0A2Z4JC06
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

2184053:DN051 RS21125
gene id: 2184053:DN051_RS21125
uniprot id: A0A2Z4J1V4
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

2184053:DN051 RS32740
gene id: 2184053:DN051_RS32740
uniprot id: A0A2Z4J6U2
names: Subcellular Location Annotation
messages: Membrane

2184053:DN051 RS19480
gene id: 2184053:DN051_RS19480
uniprot id: A0A2Z4J1J7
names: Similarity
names: Subunit
messages: Belongs to the Bpa family.
messages: Forms a homooligomeric, either hexameric or heptameric, ring-like structure which stacks co-axially with the proteasomal alpha-rings.

2184053:DN051 RS32975
gene id: 2184053:DN051_RS32975
uniprot id: A0A2Z4J7J6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MurCDEF family. MurT subfamily.
messages: Forms a heterodimer with GatD.
messages: The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The MurT subunit catalyzes the ATP-dependent amidation of D-glutamate residue of lipid II, converting it to an isoglutamine residue.

2184053:DN051 RS17360
gene id: 2184053:DN051_RS17360
uniprot id: A0A2Z4IZS4
names: Similarity
messages: Belongs to the peptidase C40 family.

2184053:DN051 RS14820
gene id: 2184053:DN051_RS14820
uniprot id: A0A2Z4IYV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

2184053:DN051 RS21385
gene id: 2184053:DN051_RS21385
uniprot id: A0A2Z4J195
names: Similarity
messages: Belongs to the peptidase C40 family.

2184053:DN051 RS14195
gene id: 2184053:DN051_RS14195
uniprot id: A0A2Z4IZN8
names: Activity Regulation
names: Caution
names: Function
names: Similarity
messages: Allosterically activated by N-acetylglucosamine 6-phosphate (GlcNAc6P).
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
messages: Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2184053:DN051 RS05615
gene id: 2184053:DN051_RS05615
uniprot id: A0A2Z4ITK3
names: Subcellular Location Annotation
messages: Membrane

2184053:DN051 RS29875
gene id: 2184053:DN051_RS29875
uniprot id: A0A2Z4J570
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

2184053:DN051 RS12960
gene id: 2184053:DN051_RS12960
uniprot id: A0A2Z4IXG3
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

2184053:DN051 RS11920
gene id: 2184053:DN051_RS11920
uniprot id: A0A2Z4IXD9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

2184053:DN051 RS21100
gene id: 2184053:DN051_RS21100
uniprot id: A0A2Z4J0T5
names: Similarity
messages: Belongs to the CsoR family.

2184053:DN051 RS03375
gene id: 2184053:DN051_RS03375
uniprot id: A0A2Z4IT67
names: Similarity
messages: Belongs to the asp23 family.

2184053:DN051 RS16965
gene id: 2184053:DN051_RS16965
uniprot id: A0A2Z4J100
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

2184053:DN051 RS16810
gene id: 2184053:DN051_RS16810
uniprot id: A0A2Z4IZ69
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

2184053:DN051 RS08465
gene id: 2184053:DN051_RS08465
uniprot id: A0A2Z4IU82
names: Similarity
messages: Belongs to the glycosyl hydrolase.

2184053:DN051 RS21670
gene id: 2184053:DN051_RS21670
uniprot id: A0A2Z4J1R2
names: Function
names: Similarity
messages: Belongs to the trehalose phosphatase family.
messages: Removes the phosphate from trehalose 6-phosphate to produce free trehalose.

2184053:DN051 RS31255
gene id: 2184053:DN051_RS31255
uniprot id: A0A2Z4J6K3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

2184053:DN051 RS31240
gene id: 2184053:DN051_RS31240
uniprot id: A0A2Z4J653
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2184053:DN051 RS12020
gene id: 2184053:DN051_RS12020
uniprot id: A0A2Z4IWZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2184053:DN051 RS25095
gene id: 2184053:DN051_RS25095
uniprot id: A0A2Z4J3G0
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

2184053:DN051 RS13685
gene id: 2184053:DN051_RS13685
uniprot id: A0A2Z4IZE3
names: Similarity
messages: Belongs to the cytochrome P450 family.

2184053:DN051 RS03445
gene id: 2184053:DN051_RS03445
uniprot id: A0A2Z4ISW8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

2184053:DN051 RS12360
gene id: 2184053:DN051_RS12360
uniprot id: A0A2Z4IXK7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

2184053:DN051 RS19835
gene id: 2184053:DN051_RS19835
uniprot id: A0A2Z4J0V4
names: Similarity
messages: Belongs to the thioredoxin family.

2184053:DN051 RS15110
gene id: 2184053:DN051_RS15110
uniprot id: A0A2Z4IYZ2
names: Subcellular Location Annotation
messages: Cytoplasm

2184053:DN051 RS27985
gene id: 2184053:DN051_RS27985
uniprot id: A0A2Z4J4B2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2184053:DN051 RS31560
gene id: 2184053:DN051_RS31560
uniprot id: A0A2Z4J6B2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase-binding protein RbpA family.
messages: Bind 1 Zn(2+) per subunit.
messages: Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters.
messages: Forms a complex with the RNAP catalytic core and with free principal sigma factors.

2184053:DN051 RS17925
gene id: 2184053:DN051_RS17925
uniprot id: A0A2Z4IZA5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2184053:DN051 RS25960
gene id: 2184053:DN051_RS25960
uniprot id: A0A2Z4J5T1
names: Similarity
messages: Belongs to the Fur family.

2184053:DN051 RS17960
gene id: 2184053:DN051_RS17960
uniprot id: A0A2Z4IZS3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DisA family.
messages: Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation; upon encountering a lesion, the DisA focus arrests at the damaged site and halts c-di-AMP synthesis.
messages: Homooctamer.
messages: Participates in a DNA-damage check-point that is active prior to asymmetric division when DNA is damaged. DisA forms globular foci that rapidly scan along the chromosomes during sporulation, searching for lesions. When a lesion is present, DisA pauses at the lesion site. This triggers a cellular response that culminates in a temporary block in sporulation initiation.

2184053:DN051 RS19640
gene id: 2184053:DN051_RS19640
uniprot id: A0A2Z4J154
names: Subcellular Location Annotation
messages: Membrane

2184053:DN051 RS08830
gene id: 2184053:DN051_RS08830
uniprot id: A0A2Z4IVY3
names: Subcellular Location Annotation
messages: Membrane

2184053:DN051 RS29400
gene id: 2184053:DN051_RS29400
uniprot id: A0A2Z4J5G8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SURF1 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2184053:DN051 RS29655
gene id: 2184053:DN051_RS29655
uniprot id: A0A2Z4J7F8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

2184053:DN051 RS17300
gene id: 2184053:DN051_RS17300
uniprot id: A0A2Z4IZ55
names: Subcellular Location Annotation
messages: Membrane

2184053:DN051 RS29895
gene id: 2184053:DN051_RS29895
uniprot id: A0A2Z4J5W7
names: Similarity
messages: Belongs to the band 7/mec-2 family.

2184053:DN051 RS39060
gene id: 2184053:DN051_RS39060
uniprot id: A0A2Z4JCT6
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

2184053:DN051 RS21455
gene id: 2184053:DN051_RS21455
uniprot id: A0A2Z4J1A1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

2184053:DN051 RS25675
gene id: 2184053:DN051_RS25675
uniprot id: A0A2Z4J330
names: Similarity
messages: Belongs to the arylamine N-acetyltransferase family.

2184053:DN051 RS19035
gene id: 2184053:DN051_RS19035
uniprot id: A0A2Z4J0K3
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

2184053:DN051 RS23215
gene id: 2184053:DN051_RS23215
uniprot id: A0A2Z4J3B8
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

2184053:DN051 RS34615
gene id: 2184053:DN051_RS34615
uniprot id: A0A2Z4J7R1
names: Similarity
messages: Belongs to the melC1 family.

2184053:DN051 RS20780
gene id: 2184053:DN051_RS20780
uniprot id: A0A2Z4J1D5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

2184053:DN051 RS17395
gene id: 2184053:DN051_RS17395
uniprot id: A0A2Z4IZ40
names: Similarity
messages: Belongs to the peptidase A24 family.

2184053:DN051 RS23600
gene id: 2184053:DN051_RS23600
uniprot id: A0A2Z4J252
names: Function
names: Similarity
messages: Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).

2184053:DN051 RS17815
gene id: 2184053:DN051_RS17815
uniprot id: A0A2Z4IZZ5
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

2184053:DN051 RS44500
gene id: 2184053:DN051_RS44500
uniprot id: A0A2Z4JF68
names: Similarity
messages: Belongs to the DprA/Smf family.

2184053:DN051 RS23525
gene id: 2184053:DN051_RS23525
uniprot id: A0A2Z4J2L3
names: Cofactor
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 1 family.
messages: Binds 1 zinc ion per subunit.

2184053:DN051 RS04815
gene id: 2184053:DN051_RS04815
uniprot id: A0A2Z4ITI7
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

2184053:DN051 RS18690
gene id: 2184053:DN051_RS18690
uniprot id: A0A2Z4J025
names: Subcellular Location Annotation
messages: Membrane

2184053:DN051 RS08895
gene id: 2184053:DN051_RS08895
uniprot id: A0A2Z4IVK2
names: Cofactor
names: Similarity
messages: Belongs to the glycosyl hydrolase 4 family.
messages: Binds 1 NAD(+) per subunit.

2184053:DN051 RS24680
gene id: 2184053:DN051_RS24680
uniprot id: A0A2Z4J3Y9
names: Similarity
messages: Belongs to the HMG-CoA lyase family.

2184053:DN051 RS16400
gene id: 2184053:DN051_RS16400
uniprot id: A0A2Z4IZ75
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

2184053:DN051 RS28975
gene id: 2184053:DN051_RS28975
uniprot id: A0A2Z4J4T8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type 2 tetrahydrodipicolinate N-succinyltransferase family.
messages: Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2-amino-6-oxopimelate using succinyl-CoA.
messages: Cytoplasm
messages: Homotrimer.

2184053:DN051 RS24345
gene id: 2184053:DN051_RS24345
uniprot id: A0A2Z4J3T9
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

2184053:DN051 RS30970
gene id: 2184053:DN051_RS30970
uniprot id: A0A2Z4J5R5
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

2184053:DN051 RS31895
gene id: 2184053:DN051_RS31895
uniprot id: A0A2Z4J652
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

2184053:DN051 RS33010
gene id: 2184053:DN051_RS33010
uniprot id: A0A2Z4J920
names: Function
names: Similarity
messages: Belongs to the ATP-dependent DNA ligase family.
messages: DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair.

2184053:DN051 RS10005
gene id: 2184053:DN051_RS10005
uniprot id: A0A2Z4IXJ6
names: Similarity
messages: Belongs to the IucA/IucC family.

2184053:DN051 RS13305
gene id: 2184053:DN051_RS13305
uniprot id: A0A2Z4IY01
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

2184053:DN051 RS36480
gene id: 2184053:DN051_RS36480
uniprot id: A0A2Z4J8F8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

2184053:DN051 RS27790
gene id: 2184053:DN051_RS27790
uniprot id: A0A2Z4J447
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

2184053:DN051 RS18170
gene id: 2184053:DN051_RS18170
uniprot id: A0A2Z4J1M0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

2184053:DN051 RS25985
gene id: 2184053:DN051_RS25985
uniprot id: A0A2Z4J4M9
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family.

2184053:DN051 RS32960
gene id: 2184053:DN051_RS32960
uniprot id: A0A2Z4J6X5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

2184053:DN051 RS27670
gene id: 2184053:DN051_RS27670
uniprot id: A0A2Z4J4P2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2184053:DN051 RS23505
gene id: 2184053:DN051_RS23505
uniprot id: A0A2Z4J2P0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lactate permease family.
messages: Cell membrane
messages: Membrane
messages: Uptake of L-lactate across the membrane. Can also transport D-lactate and glycolate.

2184053:DN051 RS21945
gene id: 2184053:DN051_RS21945
uniprot id: A0A2Z4J1C8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2184053:DN051 RS22930
gene id: 2184053:DN051_RS22930
uniprot id: A0A2Z4J369
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

2184053:DN051 RS28045
gene id: 2184053:DN051_RS28045
uniprot id: A0A2Z4J4C4
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

2184053:DN051 RS32735
gene id: 2184053:DN051_RS32735
uniprot id: A0A2Z4J8X5
names: Subcellular Location Annotation
messages: Membrane

2184053:DN051 RS28855
gene id: 2184053:DN051_RS28855
uniprot id: A0A2Z4J714
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

2184053:DN051 RS05335
gene id: 2184053:DN051_RS05335
uniprot id: A0A2Z4ITQ0
names: Function
messages: Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.

2184053:DN051 RS28965
gene id: 2184053:DN051_RS28965
uniprot id: A0A2Z4J734
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

2184053:DN051 RS27700
gene id: 2184053:DN051_RS27700
uniprot id: A0A2Z4J459
names: Similarity
messages: Belongs to the peptidase C40 family.

2184053:DN051 RS09790
gene id: 2184053:DN051_RS09790
uniprot id: A0A2Z4IVS2
names: PTM
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.
messages: Carbamylation allows a single lysine to coordinate two divalent metal cations.

2184053:DN051 RS34690
gene id: 2184053:DN051_RS34690
uniprot id: A0A2Z4J840
names: Similarity
messages: Belongs to the universal stress protein A family.

2184053:DN051 RS12170
gene id: 2184053:DN051_RS12170
uniprot id: A0A2Z4IXH6
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by GTP. Inhibited by UTP.
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2184053:DN051 RS05670
gene id: 2184053:DN051_RS05670
uniprot id: A0A2Z4IUF7
names: Subcellular Location Annotation
messages: Membrane

2184053:DN051 RS27305
gene id: 2184053:DN051_RS27305
uniprot id: A0A2Z4JC51
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

2184053:DN051 RS25740
gene id: 2184053:DN051_RS25740
uniprot id: A0A2Z4J5P3
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

2184053:DN051 RS25790
gene id: 2184053:DN051_RS25790
uniprot id: A0A2Z4J376
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenine deaminase type 2 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism.

2184053:DN051 RS21425
gene id: 2184053:DN051_RS21425
uniprot id: A0A2Z4J202
names: Function
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

2184053:DN051 RS15830
gene id: 2184053:DN051_RS15830
uniprot id: A0A2Z4IYS5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: Homotrimer.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. Cleaves guanosine, inosine, 2'-deoxyguanosine and 2'-deoxyinosine.

2184053:DN051 RS21490
gene id: 2184053:DN051_RS21490
uniprot id: A0A2Z4J152
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

2184053:DN051 RS12930
gene id: 2184053:DN051_RS12930
uniprot id: A0A2Z4IXT9
names: Similarity
messages: Belongs to the glycosyl hydrolase 25 family.

2184053:DN051 RS26005
gene id: 2184053:DN051_RS26005
uniprot id: A0A2Z4JDY4
names: Subcellular Location Annotation
messages: Membrane

2184053:DN051 RS23160
gene id: 2184053:DN051_RS23160
uniprot id: A0A2Z4J3A8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AmiS/UreI family.
messages: Membrane

2184053:DN051 RS11555
gene id: 2184053:DN051_RS11555
uniprot id: A0A2Z4IWE5
names: Similarity
messages: Belongs to the peptidase M1 family.

2184053:DN051 RS14620
gene id: 2184053:DN051_RS14620
uniprot id: A0A2Z4IZW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

2184053:DN051 RS13010
gene id: 2184053:DN051_RS13010
uniprot id: A0A2Z4IXH3
names: Function
names: Similarity
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

2184053:DN051 RS23615
gene id: 2184053:DN051_RS23615
uniprot id: A0A2Z4J3I1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpqB lipoprotein family.
messages: Cell membrane

2184053:DN051 RS24700
gene id: 2184053:DN051_RS24700
uniprot id: A0A2Z4J2N5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

2184053:DN051 RS09175
gene id: 2184053:DN051_RS09175
uniprot id: A0A2Z4IVH0
names: Subcellular Location Annotation
messages: Membrane

2184053:DN051 RS16530
gene id: 2184053:DN051_RS16530
uniprot id: A0A2Z4IZN5
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

2184053:DN051 RS24060
gene id: 2184053:DN051_RS24060
uniprot id: A0A2Z4J2X9
names: Subcellular Location Annotation
messages: Membrane

2184053:DN051 RS19805
gene id: 2184053:DN051_RS19805
uniprot id: A0A2Z4J0E8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

2184053:DN051 RS07105
gene id: 2184053:DN051_RS07105
uniprot id: A0A2Z4IUK6
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

2184053:DN051 RS31760
gene id: 2184053:DN051_RS31760
uniprot id: A0A2Z4J6K9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

2184053:DN051 RS31195
gene id: 2184053:DN051_RS31195
uniprot id: A0A2Z4J5W0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

2184053:DN051 RS16720
gene id: 2184053:DN051_RS16720
uniprot id: A0A2Z4IYY2
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

2184053:DN051 RS04450
gene id: 2184053:DN051_RS04450
uniprot id: A0A2Z4IS95
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

2184053:DN051 RS31510
gene id: 2184053:DN051_RS31510
uniprot id: A0A2Z4J622
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family.

2184053:DN051 RS02190
gene id: 2184053:DN051_RS02190
uniprot id: A0A2Z4IS69
names: Similarity
messages: Belongs to the thiolase-like superfamily. Chalcone/stilbene synthases family.

2184053:DN051 RS31450
gene id: 2184053:DN051_RS31450
uniprot id: A0A2Z4J614
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

2184053:DN051 RS17535
gene id: 2184053:DN051_RS17535
uniprot id: A0A2Z4J1A4
names: Function
names: Similarity
messages: Belongs to the MqnA/MqnD family. MqnA subfamily.
messages: Catalyzes the dehydration of chorismate into 3-[(1-carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2).

2184053:DN051 RS12890
gene id: 2184053:DN051_RS12890
uniprot id: A0A2Z4IX37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

2184053:DN051 RS12800
gene id: 2184053:DN051_RS12800
uniprot id: A0A2Z4IX20
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

2184053:DN051 RS04700
gene id: 2184053:DN051_RS04700
uniprot id: A0A2Z4ISD6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2184053:DN051 RS23280
gene id: 2184053:DN051_RS23280
uniprot id: A0A2Z4JC36
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20 family.
messages: Binds 2 Zn(2+) ions per subunit.

2184053:DN051 RS16770
gene id: 2184053:DN051_RS16770
uniprot id: A0A2Z4IYY9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

2184053:DN051 RS34850
gene id: 2184053:DN051_RS34850
uniprot id: A0A2Z4J868
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

2184053:DN051 RS27405
gene id: 2184053:DN051_RS27405
uniprot id: A0A2Z4J6E9
names: Subcellular Location Annotation
messages: Membrane

2184053:DN051 RS29355
gene id: 2184053:DN051_RS29355
uniprot id: A0A2Z4J511
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

2184053:DN051 RS10700
gene id: 2184053:DN051_RS10700
uniprot id: A0A2Z4IXU3
names: Subcellular Location Annotation
messages: Membrane

2184053:DN051 RS00865
gene id: 2184053:DN051_RS00865
uniprot id: A0A2Z4IRG6
names: Subcellular Location Annotation
messages: Cell membrane

2184053:DN051 RS16715
gene id: 2184053:DN051_RS16715
uniprot id: A0A2Z4IYU2
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

2184053:DN051 RS31400
gene id: 2184053:DN051_RS31400
uniprot id: A0A2Z4J606
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

2184053:DN051 RS20445
gene id: 2184053:DN051_RS20445
uniprot id: A0A2Z4J181
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

2184053:DN051 RS04380
gene id: 2184053:DN051_RS04380
uniprot id: A0A2Z4ITM9
names: Similarity
messages: Belongs to the TPP enzyme family.

2184053:DN051 RS30170
gene id: 2184053:DN051_RS30170
uniprot id: A0A2Z4J613
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

2184053:DN051 RS15660
gene id: 2184053:DN051_RS15660
uniprot id: A0A2Z4IYP5
names: Similarity
messages: Belongs to the AHA1 family.

2184053:DN051 RS35220
gene id: 2184053:DN051_RS35220
uniprot id: A0A2Z4JA71
names: Similarity
messages: Belongs to the peptidase S1 family.

2184053:DN051 RS27960
gene id: 2184053:DN051_RS27960
uniprot id: A0A2Z4J4T7
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2184053:DN051 RS41860
gene id: 2184053:DN051_RS41860
uniprot id: A0A2Z4JE19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2184053:DN051 RS16840
gene id: 2184053:DN051_RS16840
uniprot id: A0A2Z4IZ45
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

2184053:DN051 RS25310
gene id: 2184053:DN051_RS25310
uniprot id: A0A2Z4J3B7
names: Similarity
names: Subunit
messages: Belongs to the acetyltransferase Eis family.
messages: Homohexamer; trimer of dimers.

2184053:DN051 RS31190
gene id: 2184053:DN051_RS31190
uniprot id: A0A2Z4J646
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

2184053:DN051 RS26035
gene id: 2184053:DN051_RS26035
uniprot id: A0A2Z4J463
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.

2184053:DN051 RS15925
gene id: 2184053:DN051_RS15925
uniprot id: A0A2Z4IYE7
names: Similarity
names: Subunit
messages: Belongs to the sigma-70 factor family. ECF subfamily.
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

2184053:DN051 RS25865
gene id: 2184053:DN051_RS25865
uniprot id: A0A2Z4J435
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M4 family.
messages: Extracellular zinc metalloprotease.
messages: Secreted

2184053:DN051 RS25600
gene id: 2184053:DN051_RS25600
uniprot id: A0A2Z4J317
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein L14 (rplN).

2184053:DN051 RS34470
gene id: 2184053:DN051_RS34470
uniprot id: A0A2Z4J7N9
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus
messages: Repair polymerase that plays a key role in base-excision repair. Has 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity that removes the 5' sugar phosphate and also acts as a DNA polymerase that adds one nucleotide to the 3' end of the arising single-nucleotide gap. Conducts 'gap-filling' DNA synthesis in a stepwise distributive fashion rather than in a processive fashion as for other DNA polymerases.

2184053:DN051 RS21260
gene id: 2184053:DN051_RS21260
uniprot id: A0A2Z4J1X1
names: Caution
names: Similarity
messages: Belongs to the nitrobindin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Lacks the conserved His residue that binds heme iron in the nitrobindin family.

2184053:DN051 RS16685
gene id: 2184053:DN051_RS16685
uniprot id: A0A2Z4IZ24
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

2184053:DN051 RS13870
gene id: 2184053:DN051_RS13870
uniprot id: A0A2Z4IXR2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CbiM family.
messages: Cell membrane
messages: Forms an energy-coupling factor (ECF) transporter complex composed of an ATP-binding protein (A component, CbiO), a transmembrane protein (T component, CbiQ) and 2 possible substrate-capture proteins (S components, CbiM and CbiN) of unknown stoichimetry.
messages: Membrane
messages: Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import.

2184053:DN051 RS17095
gene id: 2184053:DN051_RS17095
uniprot id: A0A2Z4J121
names: Similarity
messages: Belongs to the UPF0234 family.

2184053:DN051 RS05425
gene id: 2184053:DN051_RS05425
uniprot id: A0A2Z4ITQ7
names: Function
names: Similarity
messages: Belongs to the HypA/HybF family.
messages: Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.

2184053:DN051 RS10615
gene id: 2184053:DN051_RS10615
uniprot id: A0A2Z4IWA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2184053:DN051 RS13185
gene id: 2184053:DN051_RS13185
uniprot id: A0A2Z4IY13
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

2184053:DN051 RS03765
gene id: 2184053:DN051_RS03765
uniprot id: A0A2Z4ITK7
names: Similarity
messages: Belongs to the myoviridae tail sheath protein family.

2184053:DN051 RS06245
gene id: 2184053:DN051_RS06245
uniprot id: A0A2Z4IU56
names: Subcellular Location Annotation
messages: Membrane

2184053:DN051 RS07980
gene id: 2184053:DN051_RS07980
uniprot id: A0A2Z4ITZ6
names: Similarity
names: Subunit
messages: Belongs to the sigma-70 factor family. ECF subfamily.
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

2184053:DN051 RS09825
gene id: 2184053:DN051_RS09825
uniprot id: A0A2Z4IXH4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

2184053:DN051 RS26475
gene id: 2184053:DN051_RS26475
uniprot id: A0A2Z4J3L3
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

2184053:DN051 RS13865
gene id: 2184053:DN051_RS13865
uniprot id: A0A2Z4IXU6
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

2184053:DN051 RS15645
gene id: 2184053:DN051_RS15645
uniprot id: A0A2Z4J0C4
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

2184053:DN051 RS09965
gene id: 2184053:DN051_RS09965
uniprot id: A0A2Z4IVL9
names: Similarity
messages: Belongs to the allantoicase family.

2184053:DN051 RS17470
gene id: 2184053:DN051_RS17470
uniprot id: A0A2Z4IZ49
names: Similarity
messages: Belongs to the GSP E family.

2184053:DN051 RS13435
gene id: 2184053:DN051_RS13435
uniprot id: A0A2Z4IZ74
names: Function
names: Similarity
messages: Belongs to the threonine synthase family.
messages: Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.

2184053:DN051 RS17580
gene id: 2184053:DN051_RS17580
uniprot id: A0A2Z4IZL2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the radical SAM superfamily. MqnE family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3-[(1-carboxyvinyl)oxy]benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate.

2184053:DN051 RS14985
gene id: 2184053:DN051_RS14985
uniprot id: A0A2Z4IYB1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

2184053:DN051 RS14885
gene id: 2184053:DN051_RS14885
uniprot id: A0A2Z4IYC0
names: Similarity
messages: Belongs to the Nudix hydrolase family.

2184053:DN051 RS27940
gene id: 2184053:DN051_RS27940
uniprot id: A0A2Z4JCG7
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Catalyzes the reversible hydration of carbon dioxide to form bicarbonate.

2184053:DN051 RS22670
gene id: 2184053:DN051_RS22670
uniprot id: A0A2Z4J273
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

2184053:DN051 RS32515
gene id: 2184053:DN051_RS32515
uniprot id: A0A2Z4J7C2
names: Similarity
messages: Belongs to the IMPACT family.

2184053:DN051 RS16445
gene id: 2184053:DN051_RS16445
uniprot id: A0A2Z4IYN8
names: Subcellular Location Annotation
messages: Membrane

2184053:DN051 RS21460
gene id: 2184053:DN051_RS21460
uniprot id: A0A2Z4J1N8
names: Subcellular Location Annotation
messages: Cell membrane

2184053:DN051 RS04070
gene id: 2184053:DN051_RS04070
uniprot id: A0A2Z4JBC8
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A lyase-type mechanism (elimination/hydration) is suggested for the cleavage of the lactyl ether bond of MurNAc 6-phosphate, with the formation of an alpha,beta-unsaturated aldehyde intermediate with (E)-stereochemistry, followed by the syn addition of water to give product.
messages: Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.
messages: Homodimer.
messages: Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate.

2184053:DN051 RS10875
gene id: 2184053:DN051_RS10875
uniprot id: A0A2Z4IWD2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2184053:DN051 RS25965
gene id: 2184053:DN051_RS25965
uniprot id: A0A2Z4J3Q3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

2184053:DN051 RS22620
gene id: 2184053:DN051_RS22620
uniprot id: A0A2Z4J294
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

2184053:DN051 RS10865
gene id: 2184053:DN051_RS10865
uniprot id: A0A2Z4IW35
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

2184053:DN051 RS11235
gene id: 2184053:DN051_RS11235
uniprot id: A0A2Z4IW81
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

2184053:DN051 RS35765
gene id: 2184053:DN051_RS35765
uniprot id: A0A2Z4J832
names: Subcellular Location Annotation
messages: Membrane

2184053:DN051 RS18915
gene id: 2184053:DN051_RS18915
uniprot id: A0A2Z4J079
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the kynureninase family.
messages: Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2184053:DN051 RS36590
gene id: 2184053:DN051_RS36590
uniprot id: A0A2Z4J8H6
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

2184053:DN051 RS30085
gene id: 2184053:DN051_RS30085
uniprot id: A0A2Z4J5B3
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

2184053:DN051 RS08715
gene id: 2184053:DN051_RS08715
uniprot id: A0A2Z4IVV8
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

2184053:DN051 RS05200
gene id: 2184053:DN051_RS05200
uniprot id: A0A2Z4ITU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2184053:DN051 RS32830
gene id: 2184053:DN051_RS32830
uniprot id: A0A2Z4J6R5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease gamma subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

2184053:DN051 RS10640
gene id: 2184053:DN051_RS10640
uniprot id: A0A2Z4IXT3
names: Subcellular Location Annotation
messages: Membrane

2184053:DN051 RS27175
gene id: 2184053:DN051_RS27175
uniprot id: A0A2Z4J4F4
names: Function
names: Similarity
messages: Belongs to the GlnE family.
messages: Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell.

2184053:DN051 RS09925
gene id: 2184053:DN051_RS09925
uniprot id: A0A2Z4IW07
names: Similarity
messages: Belongs to the cytochrome P450 family.

2184053:DN051 RS12810
gene id: 2184053:DN051_RS12810
uniprot id: A0A2Z4IXD4
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

2184053:DN051 RS25700
gene id: 2184053:DN051_RS25700
uniprot id: A0A2Z4J368
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

2184053:DN051 RS03965
gene id: 2184053:DN051_RS03965
uniprot id: A0A2Z4ITA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

2184053:DN051 RS41475
gene id: 2184053:DN051_RS41475
uniprot id: A0A2Z4JDH3
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

2184053:DN051 RS21770
gene id: 2184053:DN051_RS21770
uniprot id: A0A2Z4J1A2
names: Similarity
messages: Belongs to the CutC family.

2184053:DN051 RS04110
gene id: 2184053:DN051_RS04110
uniprot id: A0A2Z4IS28
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

2184053:DN051 RS08300
gene id: 2184053:DN051_RS08300
uniprot id: A0A2Z4JB42
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

2184053:DN051 RS22675
gene id: 2184053:DN051_RS22675
uniprot id: A0A2Z4JCX5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

2184053:DN051 RS11740
gene id: 2184053:DN051_RS11740
uniprot id: A0A2Z4IXB3
names: Similarity
messages: Belongs to the Dps family.

2184053:DN051 RS04200
gene id: 2184053:DN051_RS04200
uniprot id: A0A2Z4IT61
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

2184053:DN051 RS38760
gene id: 2184053:DN051_RS38760
uniprot id: A0A2Z4J9W8
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family. GlucD subfamily.

2184053:DN051 RS10660
gene id: 2184053:DN051_RS10660
uniprot id: A0A2Z4IWS7
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

2184053:DN051 RS21880
gene id: 2184053:DN051_RS21880
uniprot id: A0A2Z4J1G5
names: Subcellular Location Annotation
messages: Cell membrane

2184053:DN051 RS27625
gene id: 2184053:DN051_RS27625
uniprot id: A0A2Z4J415
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Membrane
messages: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).

2184053:DN051 RS25505
gene id: 2184053:DN051_RS25505
uniprot id: A0A2Z4J3H0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

2184053:DN051 RS19185
gene id: 2184053:DN051_RS19185
uniprot id: A0A2Z4J0X3
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

2184053:DN051 RS34935
gene id: 2184053:DN051_RS34935
uniprot id: A0A2Z4JCJ2
names: Subcellular Location Annotation
messages: Membrane

2184053:DN051 RS33065
gene id: 2184053:DN051_RS33065
uniprot id: A0A2Z4J6U6
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

2184053:DN051 RS14115
gene id: 2184053:DN051_RS14115
uniprot id: A0A2Z4IXX2
names: Similarity
messages: Belongs to the YciI family.

2184053:DN051 RS24600
gene id: 2184053:DN051_RS24600
uniprot id: A0A2Z4J2M1
names: Similarity
messages: Belongs to the universal stress protein A family.

2184053:DN051 RS31485
gene id: 2184053:DN051_RS31485
uniprot id: A0A2Z4J681
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CbxX/CfxQ family.
messages: Cytoplasm

2184053:DN051 RS05415
gene id: 2184053:DN051_RS05415
uniprot id: A0A2Z4IT46
names: Similarity
messages: Belongs to the peptidase A31 family.

2184053:DN051 RS10395
gene id: 2184053:DN051_RS10395
uniprot id: A0A2Z4IV65
names: Function
messages: Catalyzes the reduction of sulfite to sulfide, a step in the biosynthesis of sulfur-containing amino acids and cofactors.

2184053:DN051 RS24820
gene id: 2184053:DN051_RS24820
uniprot id: A0A2Z4J3B5
names: Subcellular Location Annotation
messages: Membrane

2184053:DN051 RS27060
gene id: 2184053:DN051_RS27060
uniprot id: A0A2Z4J3S0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

2184053:DN051 RS20060
gene id: 2184053:DN051_RS20060
uniprot id: A0A2Z4J2K6
names: Function
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: May catalyze the transamination reaction in phenylalanine biosynthesis.

2184053:DN051 RS25955
gene id: 2184053:DN051_RS25955
uniprot id: A0A2Z4J3A4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

2184053:DN051 RS22715
gene id: 2184053:DN051_RS22715
uniprot id: A0A2Z4J1I8
names: Similarity
messages: Belongs to the FAD-binding monooxygenase family.

2184053:DN051 RS06130
gene id: 2184053:DN051_RS06130
uniprot id: A0A2Z4IUH5
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

2184053:DN051 RS11275
gene id: 2184053:DN051_RS11275
uniprot id: A0A2Z4IY34
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2184053:DN051 RS31150
gene id: 2184053:DN051_RS31150
uniprot id: A0A2Z4J6G7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

2184053:DN051 RS21075
gene id: 2184053:DN051_RS21075
uniprot id: A0A2Z4J1U4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

2184053:DN051 RS25435
gene id: 2184053:DN051_RS25435
uniprot id: A0A2Z4J313
names: Function
names: Subcellular Location Annotation
messages: May play a structural or regulatory role in gas vesicle synthesis.
messages: Vesicle
messages: gas vesicle

2184053:DN051 RS12165
gene id: 2184053:DN051_RS12165
uniprot id: A0A2Z4JBU1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

2184053:DN051 RS29185
gene id: 2184053:DN051_RS29185
uniprot id: A0A2Z4J4U7
names: Function
names: Similarity
messages: Belongs to the ectoine synthase family.
messages: Catalyzes the circularization of gamma-N-acetyl-alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6-tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant.

2184053:DN051 RS27975
gene id: 2184053:DN051_RS27975
uniprot id: A0A2Z4J6N8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

2184053:DN051 RS28945
gene id: 2184053:DN051_RS28945
uniprot id: A0A2Z4J586
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

2184053:DN051 RS16800
gene id: 2184053:DN051_RS16800
uniprot id: A0A2Z4IZU1
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

2184053:DN051 RS17340
gene id: 2184053:DN051_RS17340
uniprot id: A0A2Z4IZH9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

2184053:DN051 RS08490
gene id: 2184053:DN051_RS08490
uniprot id: A0A2Z4IUW8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

2184053:DN051 RS02405
gene id: 2184053:DN051_RS02405
uniprot id: A0A2Z4ISY2
names: Similarity
messages: Belongs to the adenosylhomocysteinase family.

2184053:DN051 RS17015
gene id: 2184053:DN051_RS17015
uniprot id: A0A2Z4IZ19
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

2184053:DN051 RS35625
gene id: 2184053:DN051_RS35625
uniprot id: A0A2Z4J8U0
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

2184053:DN051 RS29790
gene id: 2184053:DN051_RS29790
uniprot id: A0A2Z4J6P1
names: Similarity
messages: Belongs to the prephenate/arogenate dehydrogenase family.

2184053:DN051 RS31055
gene id: 2184053:DN051_RS31055
uniprot id: A0A2Z4J677
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2184053:DN051 RS29315
gene id: 2184053:DN051_RS29315
uniprot id: A0A2Z4J4Z2
names: Similarity
messages: Belongs to the glycosyl hydrolase 25 family.

2184053:DN051 RS31480
gene id: 2184053:DN051_RS31480
uniprot id: A0A2Z4J6I7
names: Subcellular Location Annotation
messages: Membrane

2184053:DN051 RS20035
gene id: 2184053:DN051_RS20035
uniprot id: A0A2Z4J1V5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

2184053:DN051 RS26795
gene id: 2184053:DN051_RS26795
uniprot id: A0A2Z4J482
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

2184053:DN051 RS39190
gene id: 2184053:DN051_RS39190
uniprot id: A0A2Z4JA13
names: Subcellular Location Annotation
messages: Membrane

2184053:DN051 RS17990
gene id: 2184053:DN051_RS17990
uniprot id: A0A2Z4IZB0
names: Subcellular Location Annotation
messages: Cell membrane

2184053:DN051 RS24640
gene id: 2184053:DN051_RS24640
uniprot id: A0A2Z4J381
names: Similarity
messages: Belongs to the lysine N(6)-hydroxylase/L-ornithine N(5)-oxygenase family.

2184053:DN051 RS12795
gene id: 2184053:DN051_RS12795
uniprot id: A0A2Z4IWJ7
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

2184053:DN051 RS10375
gene id: 2184053:DN051_RS10375
uniprot id: A0A2Z4IW22
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

2184053:DN051 RS17955
gene id: 2184053:DN051_RS17955
uniprot id: A0A2Z4J0C3
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

2184053:DN051 RS32810
gene id: 2184053:DN051_RS32810
uniprot id: A0A2Z4J861
names: Similarity
messages: Belongs to the peptidase C40 family.

2184053:DN051 RS41315
gene id: 2184053:DN051_RS41315
uniprot id: A0A2Z4JDS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2184053:DN051 RS16610
gene id: 2184053:DN051_RS16610
uniprot id: A0A2Z4IYR9
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

2184053:DN051 RS16855
gene id: 2184053:DN051_RS16855
uniprot id: A0A2Z4IZA6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

2184053:DN051 RS18195
gene id: 2184053:DN051_RS18195
uniprot id: A0A2Z4J0N7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

2184053:DN051 RS17295
gene id: 2184053:DN051_RS17295
uniprot id: A0A2Z4IZ26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

2184053:DN051 RS13235
gene id: 2184053:DN051_RS13235
uniprot id: A0A2Z4IY19
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

2184053:DN051 RS13295
gene id: 2184053:DN051_RS13295
uniprot id: A0A2Z4IY25
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

2184053:DN051 RS34090
gene id: 2184053:DN051_RS34090
uniprot id: A0A2Z4J827
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2184053:DN051 RS22790
gene id: 2184053:DN051_RS22790
uniprot id: A0A2Z4J434
names: Subcellular Location Annotation
messages: Membrane

2184053:DN051 RS22880
gene id: 2184053:DN051_RS22880
uniprot id: A0A2Z4J357
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

2184053:DN051 RS31565
gene id: 2184053:DN051_RS31565
uniprot id: A0A2Z4J631
names: Subcellular Location Annotation
messages: Membrane

2184053:DN051 RS04775
gene id: 2184053:DN051_RS04775
uniprot id: A0A2Z4IV29
names: Similarity
messages: Belongs to the pirin family.

2184053:DN051 RS22870
gene id: 2184053:DN051_RS22870
uniprot id: A0A2Z4J2D0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

2184053:DN051 RS41850
gene id: 2184053:DN051_RS41850
uniprot id: A0A2Z4JED3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

2184053:DN051 RS10475
gene id: 2184053:DN051_RS10475
uniprot id: A0A2Z4JDA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2184053:DN051 RS11685
gene id: 2184053:DN051_RS11685
uniprot id: A0A2Z4IXA1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

2184053:DN051 RS09160
gene id: 2184053:DN051_RS09160
uniprot id: A0A2Z4JBP2
names: Similarity
messages: Belongs to the TPP enzyme family.

2184053:DN051 RS32705
gene id: 2184053:DN051_RS32705
uniprot id: A0A2Z4J842
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

2184053:DN051 RS16860
gene id: 2184053:DN051_RS16860
uniprot id: A0A2Z4IZU9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

2184053:DN051 RS16590
gene id: 2184053:DN051_RS16590
uniprot id: A0A2Z4IZ22
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

2184053:DN051 RS16805
gene id: 2184053:DN051_RS16805
uniprot id: A0A2Z4IZ52
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

2184053:DN051 RS19860
gene id: 2184053:DN051_RS19860
uniprot id: A0A2Z4J0F1
names: Subcellular Location Annotation
messages: Membrane

2184053:DN051 RS25500
gene id: 2184053:DN051_RS25500
uniprot id: A0A2Z4J5K0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

2184053:DN051 RS31280
gene id: 2184053:DN051_RS31280
uniprot id: A0A2Z4J5V6
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2184053:DN051 RS21695
gene id: 2184053:DN051_RS21695
uniprot id: A0A2Z4J1D7
names: Subcellular Location Annotation
messages: Cytoplasm

2184053:DN051 RS31160
gene id: 2184053:DN051_RS31160
uniprot id: A0A2Z4J7B4
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

2184053:DN051 RS11365
gene id: 2184053:DN051_RS11365
uniprot id: A0A2Z4IVN4
names: Subcellular Location Annotation
messages: Cytoplasm

2184053:DN051 RS13350
gene id: 2184053:DN051_RS13350
uniprot id: A0A2Z4IY33
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

2184053:DN051 RS14225
gene id: 2184053:DN051_RS14225
uniprot id: A0A2Z4IYI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

2184053:DN051 RS13925
gene id: 2184053:DN051_RS13925
uniprot id: A0A2Z4IYE4
names: Subcellular Location Annotation
messages: Membrane

2184053:DN051 RS27595
gene id: 2184053:DN051_RS27595
uniprot id: A0A2Z4JC35
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 3 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

2184053:DN051 RS32965
gene id: 2184053:DN051_RS32965
uniprot id: A0A2Z4J6P7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2184053:DN051 RS06305
gene id: 2184053:DN051_RS06305
uniprot id: A0A2Z4IUC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2184053:DN051 RS11665
gene id: 2184053:DN051_RS11665
uniprot id: A0A2Z4IX98
names: Similarity
messages: Belongs to the cysteine dioxygenase family.

2184053:DN051 RS03225
gene id: 2184053:DN051_RS03225
uniprot id: A0A2Z4ISP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2184053:DN051 RS26750
gene id: 2184053:DN051_RS26750
uniprot id: A0A2Z4J3M7
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

2184053:DN051 RS16350
gene id: 2184053:DN051_RS16350
uniprot id: A0A2Z4IZ66
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

2184053:DN051 RS28180
gene id: 2184053:DN051_RS28180
uniprot id: A0A2Z4J4W8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

2184053:DN051 RS14795
gene id: 2184053:DN051_RS14795
uniprot id: A0A2Z4IXV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

2184053:DN051 RS17035
gene id: 2184053:DN051_RS17035
uniprot id: A0A2Z4IZ71
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

2184053:DN051 RS11995
gene id: 2184053:DN051_RS11995
uniprot id: A0A2Z4IWY6
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

2184053:DN051 RS27750
gene id: 2184053:DN051_RS27750
uniprot id: A0A2Z4J4K1
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

2184053:DN051 RS25355
gene id: 2184053:DN051_RS25355
uniprot id: A0A2Z4J3U4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

2184053:DN051 RS17030
gene id: 2184053:DN051_RS17030
uniprot id: A0A2Z4IZL4
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.

2184053:DN051 RS18725
gene id: 2184053:DN051_RS18725
uniprot id: A0A2Z4J0P8
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

2184053:DN051 RS13995
gene id: 2184053:DN051_RS13995
uniprot id: A0A2Z4IXX5
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

2184053:DN051 RS33875
gene id: 2184053:DN051_RS33875
uniprot id: A0A2Z4J784
names: Function
names: Similarity
names: Subunit
messages: Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.
messages: Homotetramer.
messages: Uses inorganic polyphosphate (polyP) as a donor to convert GDP to GTP or ADP to ATP.

2184053:DN051 RS29140
gene id: 2184053:DN051_RS29140
uniprot id: A0A2Z4J4T2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Membrane

2184053:DN051 RS31215
gene id: 2184053:DN051_RS31215
uniprot id: A0A2Z4J6A8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

2184053:DN051 RS19800
gene id: 2184053:DN051_RS19800
uniprot id: A0A2Z4J0W9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

2184053:DN051 RS25195
gene id: 2184053:DN051_RS25195
uniprot id: A0A2Z4J394
names: Similarity
messages: Belongs to the disproportionating enzyme family.

2184053:DN051 RS11975
gene id: 2184053:DN051_RS11975
uniprot id: A0A2Z4IWM4
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

2184053:DN051 RS05880
gene id: 2184053:DN051_RS05880
uniprot id: A0A2Z4JBE3
names: Similarity
messages: Belongs to the CsoR family.

2184053:DN051 RS23350
gene id: 2184053:DN051_RS23350
uniprot id: A0A2Z4J1W9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

2184053:DN051 RS31230
gene id: 2184053:DN051_RS31230
uniprot id: A0A2Z4J5U6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

2184053:DN051 RS13025
gene id: 2184053:DN051_RS13025
uniprot id: A0A2Z4IXD6
names: Similarity
messages: Belongs to the peptidase S8 family.

2184053:DN051 RS28140
gene id: 2184053:DN051_RS28140
uniprot id: A0A2Z4J6R0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

2184053:DN051 RS38345
gene id: 2184053:DN051_RS38345
uniprot id: A0A2Z4J9N9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane

2184053:DN051 RS42210
gene id: 2184053:DN051_RS42210
uniprot id: A0A2Z4JF25
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

2184053:DN051 RS11860
gene id: 2184053:DN051_RS11860
uniprot id: A0A2Z4IWK1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

2184053:DN051 RS08410
gene id: 2184053:DN051_RS08410
uniprot id: A0A2Z4IV18
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the zinc-containing alcohol dehydrogenase family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate.
messages: Cytoplasm
messages: Homotetramer.

2184053:DN051 RS42995
gene id: 2184053:DN051_RS42995
uniprot id: A0A2Z4JEJ0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2184053:DN051 RS06225
gene id: 2184053:DN051_RS06225
uniprot id: A0A2Z4IUQ1
names: Similarity
messages: Belongs to the peptidase S33 family.

2184053:DN051 RS20165
gene id: 2184053:DN051_RS20165
uniprot id: A0A2Z4J0M3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the DyP-type peroxidase family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group non-covalently per subunit.
messages: Involved in the recovery of exogenous heme iron. Extracts iron from heme while preserving the protoporphyrin ring intact.

2184053:DN051 RS35375
gene id: 2184053:DN051_RS35375
uniprot id: A0A2Z4J8E5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2184053:DN051 RS23355
gene id: 2184053:DN051_RS23355
uniprot id: A0A2Z4J222
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2184053:DN051 RS24560
gene id: 2184053:DN051_RS24560
uniprot id: A0A2Z4J2L0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2184053:DN051 RS18230
gene id: 2184053:DN051_RS18230
uniprot id: A0A2Z4IZP3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

2184053:DN051 RS29425
gene id: 2184053:DN051_RS29425
uniprot id: A0A2Z4J4Y2
names: Subcellular Location Annotation
messages: Membrane

2184053:DN051 RS27440
gene id: 2184053:DN051_RS27440
uniprot id: A0A2Z4JCK0
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

2184053:DN051 RS31075
gene id: 2184053:DN051_RS31075
uniprot id: A0A2Z4J837
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.

2184053:DN051 RS14205
gene id: 2184053:DN051_RS14205
uniprot id: A0A2Z4IXX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2184053:DN051 RS25590
gene id: 2184053:DN051_RS25590
uniprot id: A0A2Z4J3G5
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

2184053:DN051 RS12710
gene id: 2184053:DN051_RS12710
uniprot id: A0A2Z4IX75
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2184053:DN051 RS33235
gene id: 2184053:DN051_RS33235
uniprot id: A0A2Z4J959
names: Similarity
messages: Belongs to the UPF0047 family.

2184053:DN051 RS12210
gene id: 2184053:DN051_RS12210
uniprot id: A0A2Z4IXI5
names: Similarity
messages: Belongs to the UPF0102 family.

2184053:DN051 RS04295
gene id: 2184053:DN051_RS04295
uniprot id: A0A2Z4ISK7
names: Similarity
messages: Belongs to the universal stress protein A family.

2184053:DN051 RS31515
gene id: 2184053:DN051_RS31515
uniprot id: A0A2Z4J6N5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

2184053:DN051 RS12175
gene id: 2184053:DN051_RS12175
uniprot id: A0A2Z4IX16
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

2184053:DN051 RS33075
gene id: 2184053:DN051_RS33075
uniprot id: A0A2Z4J6Z1
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the xylose isomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2184053:DN051 RS10770
gene id: 2184053:DN051_RS10770
uniprot id: A0A2Z4IWB1
names: Subcellular Location Annotation
messages: Membrane

2184053:DN051 RS31275
gene id: 2184053:DN051_RS31275
uniprot id: A0A2Z4J5Z2
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

2184053:DN051 RS22630
gene id: 2184053:DN051_RS22630
uniprot id: A0A2Z4JC26
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Although this enzyme belongs to the family of MTA phosphorylases based on sequence homology, it lacks several conserved amino acids in the substrate binding pocket that confer specificity towards MTA.
messages: Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
messages: Homohexamer. Dimer of a homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Purine nucleoside phosphorylase involved in purine salvage.

2184053:DN051 RS29490
gene id: 2184053:DN051_RS29490
uniprot id: A0A2Z4J514
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

2184053:DN051 RS28835
gene id: 2184053:DN051_RS28835
uniprot id: A0A2Z4JD87
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

2184053:DN051 RS12345
gene id: 2184053:DN051_RS12345
uniprot id: A0A2Z4IYN6
names: Similarity
messages: Belongs to the acylphosphatase family.

2184053:DN051 RS12195
gene id: 2184053:DN051_RS12195
uniprot id: A0A2Z4IYK1
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

2184053:DN051 RS15895
gene id: 2184053:DN051_RS15895
uniprot id: A0A2Z4IYQ2
names: Subcellular Location Annotation
messages: Membrane

2184053:DN051 RS17800
gene id: 2184053:DN051_RS17800
uniprot id: A0A2Z4IZH8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transcriptional regulatory Rex family.
messages: Cytoplasm
messages: Homodimer.
messages: Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.

2184053:DN051 RS34495
gene id: 2184053:DN051_RS34495
uniprot id: A0A2Z4J8X0
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of adenosine and 2-deoxyadenosine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2184053:DN051 RS11655
gene id: 2184053:DN051_RS11655
uniprot id: A0A2Z4IWT9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

2184053:DN051 RS32535
gene id: 2184053:DN051_RS32535
uniprot id: A0A2Z4J6R1
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

2184053:DN051 RS25805
gene id: 2184053:DN051_RS25805
uniprot id: A0A2Z4J388
names: Similarity
messages: Belongs to the DapA family.

2184053:DN051 RS17280
gene id: 2184053:DN051_RS17280
uniprot id: A0A2Z4J021
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

2184053:DN051 RS21055
gene id: 2184053:DN051_RS21055
uniprot id: A0A2Z4JBZ6
names: Similarity
messages: Belongs to the peptidase C40 family.

2184053:DN051 RS16585
gene id: 2184053:DN051_RS16585
uniprot id: A0A2Z4IZP6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cell surface
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
messages: capsule
messages: cell wall

2184053:DN051 RS09895
gene id: 2184053:DN051_RS09895
uniprot id: A0A2Z4IVU1
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

2184053:DN051 RS22875
gene id: 2184053:DN051_RS22875
uniprot id: A0A2Z4JBJ8
names: Cofactor
names: Similarity
messages: Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.
messages: Binds 1 zinc ion per subunit.

2184053:DN051 RS41560
gene id: 2184053:DN051_RS41560
uniprot id: A0A2Z4JER9
names: Subcellular Location Annotation
messages: Cell membrane

2184053:DN051 RS15045
gene id: 2184053:DN051_RS15045
uniprot id: A0A2Z4IYF0
names: Similarity
messages: Belongs to the proline racemase family.

2184053:DN051 RS30105
gene id: 2184053:DN051_RS30105
uniprot id: A0A2Z4J5C7
names: Function
messages: TetR is the repressor of the tetracycline resistance element; its N-terminal region forms a helix-turn-helix structure and binds DNA. Binding of tetracycline to TetR reduces the repressor affinity for the tetracycline resistance gene (tetA) promoter operator sites.

2184053:DN051 RS31455
gene id: 2184053:DN051_RS31455
uniprot id: A0A2Z4J6M5
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

2184053:DN051 RS34055
gene id: 2184053:DN051_RS34055
uniprot id: A0A2Z4J7W8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane

2184053:DN051 RS31370
gene id: 2184053:DN051_RS31370
uniprot id: A0A2Z4J6E3
names: Similarity
messages: Belongs to the barstar family.

2184053:DN051 RS34655
gene id: 2184053:DN051_RS34655
uniprot id: A0A2Z4J7Y5
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

2184053:DN051 RS17785
gene id: 2184053:DN051_RS17785
uniprot id: A0A2Z4IZP7
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

2184053:DN051 RS35370
gene id: 2184053:DN051_RS35370
uniprot id: A0A2Z4J824
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2184053:DN051 RS22885
gene id: 2184053:DN051_RS22885
uniprot id: A0A2Z4J1Y8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. GalK subfamily.
messages: Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P).
messages: Cytoplasm

2184053:DN051 RS24285
gene id: 2184053:DN051_RS24285
uniprot id: A0A2Z4J3T4
names: Subcellular Location Annotation
messages: Membrane

2184053:DN051 RS28010
gene id: 2184053:DN051_RS28010
uniprot id: A0A2Z4J4U6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SepF family.
messages: Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
messages: Cytoplasm
messages: Homodimer. Interacts with FtsZ.

2184053:DN051 RS32835
gene id: 2184053:DN051_RS32835
uniprot id: A0A2Z4J8Z3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease beta subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

2184053:DN051 RS25830
gene id: 2184053:DN051_RS25830
uniprot id: A0A2Z4J3U1
names: Subcellular Location Annotation
messages: Membrane

2184053:DN051 RS14335
gene id: 2184053:DN051_RS14335
uniprot id: A0A2Z4IXZ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

2184053:DN051 RS08790
gene id: 2184053:DN051_RS08790
uniprot id: A0A2Z4IVU5
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

2184053:DN051 RS24120
gene id: 2184053:DN051_RS24120
uniprot id: A0A2Z4J2E2
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

2184053:DN051 RS29475
gene id: 2184053:DN051_RS29475
uniprot id: A0A2Z4J501
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

2184053:DN051 RS35210
gene id: 2184053:DN051_RS35210
uniprot id: A0A2Z4J812
names: Similarity
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.

2184053:DN051 RS24965
gene id: 2184053:DN051_RS24965
uniprot id: A0A2Z4J3B9
names: Subcellular Location Annotation
messages: Membrane

2184053:DN051 RS11825
gene id: 2184053:DN051_RS11825
uniprot id: A0A2Z4IXC3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

2184053:DN051 RS30660
gene id: 2184053:DN051_RS30660
uniprot id: A0A2Z4J690
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

2184053:DN051 RS13070
gene id: 2184053:DN051_RS13070
uniprot id: A0A2Z4IXZ3
names: Subcellular Location Annotation
messages: Membrane

2184053:DN051 RS31645
gene id: 2184053:DN051_RS31645
uniprot id: A0A2Z4J6J1
names: Subcellular Location Annotation
messages: Membrane

2184053:DN051 RS15040
gene id: 2184053:DN051_RS15040
uniprot id: A0A2Z4IYZ0
names: Similarity
messages: Belongs to the DapA family.

2184053:DN051 RS08915
gene id: 2184053:DN051_RS08915
uniprot id: A0A2Z4IX28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2184053:DN051 RS10090
gene id: 2184053:DN051_RS10090
uniprot id: A0A2Z4IVX3
names: Similarity
messages: Belongs to the hyi family.

2184053:DN051 RS29190
gene id: 2184053:DN051_RS29190
uniprot id: A0A2Z4J4U4
names: Function
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
messages: Catalyzes reversively the conversion of L-aspartate beta-semialdehyde (ASA) to L-2,4-diaminobutyrate (DABA) by transamination with L-glutamate.

2184053:DN051 RS27970
gene id: 2184053:DN051_RS27970
uniprot id: A0A2Z4J475
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

2184053:DN051 RS22000
gene id: 2184053:DN051_RS22000
uniprot id: A0A2Z4J3I4
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

2184053:DN051 RS15435
gene id: 2184053:DN051_RS15435
uniprot id: A0A2Z4J095
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

2184053:DN051 RS11595
gene id: 2184053:DN051_RS11595
uniprot id: A0A2Z4IY97
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

2184053:DN051 RS08590
gene id: 2184053:DN051_RS08590
uniprot id: A0A2Z4IWW1
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

2184053:DN051 RS20570
gene id: 2184053:DN051_RS20570
uniprot id: A0A2Z4J0L0
names: Similarity
messages: Belongs to the Nudix hydrolase family.

2184053:DN051 RS10455
gene id: 2184053:DN051_RS10455
uniprot id: A0A2Z4IW04
names: Subcellular Location Annotation
messages: Membrane

2184053:DN051 RS03860
gene id: 2184053:DN051_RS03860
uniprot id: A0A2Z4ISE2
names: Similarity
messages: Belongs to the FGGY kinase family.

2184053:DN051 RS15050
gene id: 2184053:DN051_RS15050
uniprot id: A0A2Z4IYY4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2184053:DN051 RS08110
gene id: 2184053:DN051_RS08110
uniprot id: A0A2Z4JC99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM175 family.
messages: Membrane

2184053:DN051 RS26380
gene id: 2184053:DN051_RS26380
uniprot id: A0A2Z4J441
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

2184053:DN051 RS19445
gene id: 2184053:DN051_RS19445
uniprot id: A0A2Z4J0A2
names: Similarity
messages: Belongs to the peptidase S11 family.

2184053:DN051 RS13075
gene id: 2184053:DN051_RS13075
uniprot id: A0A2Z4IXE7
names: Subcellular Location Annotation
messages: Cytoplasm

2184053:DN051 RS26880
gene id: 2184053:DN051_RS26880
uniprot id: A0A2Z4J4K8
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

2184053:DN051 RS16995
gene id: 2184053:DN051_RS16995
uniprot id: A0A2Z4IZW8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

2184053:DN051 RS30430
gene id: 2184053:DN051_RS30430
uniprot id: A0A2Z4J626
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
messages: Cytoplasm
messages: The 20S proteasome core is composed of 14 alpha and 14 beta subunits that assemble into four stacked heptameric rings, resulting in a barrel-shaped structure. The two inner rings, each composed of seven catalytic beta subunits, are sandwiched by two outer rings, each composed of seven alpha subunits. The catalytic chamber with the active sites is on the inside of the barrel. Has a gated structure, the ends of the cylinder being occluded by the N-termini of the alpha-subunits. Is capped by the proteasome-associated ATPase, ARC.
messages: The formation of the proteasomal ATPase ARC-20S proteasome complex, likely via the docking of the C-termini of ARC into the intersubunit pockets in the alpha-rings, may trigger opening of the gate for substrate entry. Interconversion between the open-gate and close-gate conformations leads to a dynamic regulation of the 20S proteasome proteolysis activity.

2184053:DN051 RS17000
gene id: 2184053:DN051_RS17000
uniprot id: A0A2Z4IZB3
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

2184053:DN051 RS30390
gene id: 2184053:DN051_RS30390
uniprot id: A0A2Z4J5T6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM61 family.
messages: Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA.
messages: Homotetramer composed of a dimer of dimers.

2184053:DN051 RS24430
gene id: 2184053:DN051_RS24430
uniprot id: A0A2Z4J504
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

2184053:DN051 RS31350
gene id: 2184053:DN051_RS31350
uniprot id: A0A2Z4J5Z5
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

2184053:DN051 RS23170
gene id: 2184053:DN051_RS23170
uniprot id: A0A2Z4J2H5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane

2184053:DN051 RS16815
gene id: 2184053:DN051_RS16815
uniprot id: A0A2Z4IYW4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

2184053:DN051 RS21130
gene id: 2184053:DN051_RS21130
uniprot id: A0A2Z4J1F1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

2184053:DN051 RS04635
gene id: 2184053:DN051_RS04635
uniprot id: A0A2Z4JAL0
names: Similarity
names: Subunit
messages: Belongs to the sigma-70 factor family. ECF subfamily.
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

2184053:DN051 RS23760
gene id: 2184053:DN051_RS23760
uniprot id: A0A2Z4J4M2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division.

2184053:DN051 RS18920
gene id: 2184053:DN051_RS18920
uniprot id: A0A2Z4IZR8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tryptophan 2,3-dioxygenase family.
messages: Binds 1 heme group per subunit.
messages: Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L-tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2184053:DN051 RS31460
gene id: 2184053:DN051_RS31460
uniprot id: A0A2Z4JCS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA-PH family.
messages: Cytoplasm

2184053:DN051 RS27655
gene id: 2184053:DN051_RS27655
uniprot id: A0A2Z4J4P9
names: Caution
names: PTM
names: Subcellular Location Annotation
names: Subunit
messages: Binds 2 heme c groups covalently per subunit.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The cytochrome bc1 complex is composed of a cytochrome b (QcrB), the Rieske iron-sulfur protein (QcrA) and a diheme cytochrome c (QcrC) subunit.

2184053:DN051 RS26135
gene id: 2184053:DN051_RS26135
uniprot id: A0A2Z4J3F0
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

2184053:DN051 RS16755
gene id: 2184053:DN051_RS16755
uniprot id: A0A2Z4IZ43
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

2184053:DN051 RS27115
gene id: 2184053:DN051_RS27115
uniprot id: A0A2Z4J3S8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

2184053:DN051 RS29180
gene id: 2184053:DN051_RS29180
uniprot id: A0A2Z4J5B0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PhyH family. EctD subfamily.
messages: Homodimer.
messages: Involved in the biosynthesis of 5-hydroxyectoine, called compatible solute, which helps organisms to survive extreme osmotic stress by acting as a highly soluble organic osmolyte. Catalyzes the 2-oxoglutarate-dependent selective hydroxylation of L-ectoine to yield (4S,5S)-5-hydroxyectoine.

2184053:DN051 RS18870
gene id: 2184053:DN051_RS18870
uniprot id: A0A2Z4J1Z4
names: Similarity
messages: Belongs to the cytochrome P450 family.

2184053:DN051 RS16345
gene id: 2184053:DN051_RS16345
uniprot id: A0A2Z4J0P1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

2184053:DN051 RS21090
gene id: 2184053:DN051_RS21090
uniprot id: A0A2Z4J155
names: Subcellular Location Annotation
messages: Membrane

2184053:DN051 RS17255
gene id: 2184053:DN051_RS17255
uniprot id: A0A2Z4J150
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

2184053:DN051 RS14255
gene id: 2184053:DN051_RS14255
uniprot id: A0A2Z4IXG5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

2184053:DN051 RS30770
gene id: 2184053:DN051_RS30770
uniprot id: A0A2Z4J5N4
names: Function
names: Similarity
messages: Belongs to the ApbE family.
messages: Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.

2184053:DN051 RS34260
gene id: 2184053:DN051_RS34260
uniprot id: A0A2Z4J855
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

2184053:DN051 RS22045
gene id: 2184053:DN051_RS22045
uniprot id: A0A2Z4J1Z0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DtxR/MntR family.
messages: Cytoplasm
messages: Homodimer.

2184053:DN051 RS17335
gene id: 2184053:DN051_RS17335
uniprot id: A0A2Z4IZG8
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.

2184053:DN051 RS09110
gene id: 2184053:DN051_RS09110
uniprot id: A0A2Z4JBD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2184053:DN051 RS28910
gene id: 2184053:DN051_RS28910
uniprot id: A0A2Z4JC78
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

2184053:DN051 RS12685
gene id: 2184053:DN051_RS12685
uniprot id: A0A2Z4IYV2
names: Cofactor
messages: Binds 1 FAD per subunit.

2184053:DN051 RS07020
gene id: 2184053:DN051_RS07020
uniprot id: A0A2Z4IUH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2184053:DN051 RS16250
gene id: 2184053:DN051_RS16250
uniprot id: A0A2Z4IZ39
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

2184053:DN051 RS28200
gene id: 2184053:DN051_RS28200
uniprot id: A0A2Z4J4S2
names: Similarity
messages: Belongs to the TrpC family.

2184053:DN051 RS15950
gene id: 2184053:DN051_RS15950
uniprot id: A0A2Z4IZD2
names: Subcellular Location Annotation
messages: Membrane

2184053:DN051 RS17355
gene id: 2184053:DN051_RS17355
uniprot id: A0A2Z4J167
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

2184053:DN051 RS16120
gene id: 2184053:DN051_RS16120
uniprot id: A0A2Z4IZG7
names: Cofactor
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.

2184053:DN051 RS28985
gene id: 2184053:DN051_RS28985
uniprot id: A0A2Z4JCI6
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

2184053:DN051 RS18575
gene id: 2184053:DN051_RS18575
uniprot id: A0A2Z4IZL0
names: Subcellular Location Annotation
messages: Membrane

2184053:DN051 RS12920
gene id: 2184053:DN051_RS12920
uniprot id: A0A2Z4IXW1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2184053:DN051 RS16795
gene id: 2184053:DN051_RS16795
uniprot id: A0A2Z4IZA3
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

2184053:DN051 RS30810
gene id: 2184053:DN051_RS30810
uniprot id: A0A2Z4J5N1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

2184053:DN051 RS04630
gene id: 2184053:DN051_RS04630
uniprot id: A0A2Z4ISC6
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

2184053:DN051 RS25785
gene id: 2184053:DN051_RS25785
uniprot id: A0A2Z4J353
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase Z family.
messages: Binds 2 Zn(2+) ions.
messages: Homodimer.
messages: Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.

2184053:DN051 RS12415
gene id: 2184053:DN051_RS12415
uniprot id: A0A2Z4IXL7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

2184053:DN051 RS22555
gene id: 2184053:DN051_RS22555
uniprot id: A0A2Z4J258
names: Similarity
messages: Belongs to the DODA-type extradiol aromatic ring-opening dioxygenase family.

2184053:DN051 RS41780
gene id: 2184053:DN051_RS41780
uniprot id: A0A2Z4JDK0
names: Similarity
messages: Belongs to the myoviridae tail sheath protein family.

2184053:DN051 RS06570
gene id: 2184053:DN051_RS06570
uniprot id: A0A2Z4IUV7
names: Function
messages: Catalyzes the hydrolysis of the gamma-glutamyl amide bond of hercynyl-gamma-L-glutamyl-L-cysteine sulfoxide to produce hercynylcysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine.

2184053:DN051 RS37380
gene id: 2184053:DN051_RS37380
uniprot id: A0A2Z4J9L8
names: Similarity
messages: Belongs to the cysteine dioxygenase family.

2184053:DN051 RS29450
gene id: 2184053:DN051_RS29450
uniprot id: A0A2Z4J5J4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

2184053:DN051 RS13100
gene id: 2184053:DN051_RS13100
uniprot id: A0A2Z4IWU4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2184053:DN051 RS22125
gene id: 2184053:DN051_RS22125
uniprot id: A0A2Z4J1E8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

2184053:DN051 RS22040
gene id: 2184053:DN051_RS22040
uniprot id: A0A2Z4J1J4
names: Similarity
messages: Belongs to the UPF0309 family.

2184053:DN051 RS29560
gene id: 2184053:DN051_RS29560
uniprot id: A0A2Z4J5L4
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxygen, probably at the conserved histidine residue, and transfers its phosphate group probably to a conserved aspartate residue of NreC. NreB/NreC activates the expression of the nitrate (narGHJI) and nitrite (nir) reductase operons, as well as the putative nitrate transporter gene narT.

2184053:DN051 RS16175
gene id: 2184053:DN051_RS16175
uniprot id: A0A2Z4IYX8
names: Subcellular Location Annotation
messages: Membrane

2184053:DN051 RS08365
gene id: 2184053:DN051_RS08365
uniprot id: A0A2Z4IV36
names: Similarity
messages: Belongs to the Fur family.

2184053:DN051 RS31315
gene id: 2184053:DN051_RS31315
uniprot id: A0A2Z4J6C9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

2184053:DN051 RS25690
gene id: 2184053:DN051_RS25690
uniprot id: A0A2Z4J5N2
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

2184053:DN051 RS05935
gene id: 2184053:DN051_RS05935
uniprot id: A0A2Z4IVP7
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

2184053:DN051 RS20135
gene id: 2184053:DN051_RS20135
uniprot id: A0A2Z4J109
names: Subcellular Location Annotation
messages: Membrane

2184053:DN051 RS31305
gene id: 2184053:DN051_RS31305
uniprot id: A0A2Z4J6L2
names: Similarity
messages: Belongs to the OMP decarboxylase family. Type 2 subfamily.

2184053:DN051 RS06845
gene id: 2184053:DN051_RS06845
uniprot id: A0A2Z4IUV0
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

2184053:DN051 RS33175
gene id: 2184053:DN051_RS33175
uniprot id: A0A2Z4J716
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
messages: Part of the 50S ribosomal subunit.

2184053:DN051 RS29485
gene id: 2184053:DN051_RS29485
uniprot id: A0A2Z4J5C9
names: Similarity
messages: Belongs to the peptidase U62 family.

2184053:DN051 RS28690
gene id: 2184053:DN051_RS28690
uniprot id: A0A2Z4J4K2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

2184053:DN051 RS15965
gene id: 2184053:DN051_RS15965
uniprot id: A0A2Z4IYT2
names: Similarity
messages: Belongs to the BMP lipoprotein family.

2184053:DN051 RS05440
gene id: 2184053:DN051_RS05440
uniprot id: A0A2Z4IUC1
names: Similarity
messages: Belongs to the HupF/HypC family.