215578:ESOMN RS00110
gene id: 215578:ESOMN_RS00110
uniprot id: A0A2K8NYW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

215578:ESOMN RS00695
gene id: 215578:ESOMN_RS00695
uniprot id: A0A2K8NXF9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

215578:ESOMN RS03365
gene id: 215578:ESOMN_RS03365
uniprot id: A0A2K8NZ65
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

215578:ESOMN RS01325
gene id: 215578:ESOMN_RS01325
uniprot id: A0A2K8NYL7
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

215578:ESOMN RS00330
gene id: 215578:ESOMN_RS00330
uniprot id: A0A2K8P0M9
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

215578:ESOMN RS00370
gene id: 215578:ESOMN_RS00370
uniprot id: A0A2K8P0D1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arginine deiminase family.
messages: Cytoplasm

215578:ESOMN RS01850
gene id: 215578:ESOMN_RS01850
uniprot id: A0A2K8NY41
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

215578:ESOMN RS01145
gene id: 215578:ESOMN_RS01145
uniprot id: A0A2K8NXR1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

215578:ESOMN RS03305
gene id: 215578:ESOMN_RS03305
uniprot id: A0A2K8P296
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

215578:ESOMN RS03760
gene id: 215578:ESOMN_RS03760
uniprot id: A0A2K8NZ59
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

215578:ESOMN RS02270
gene id: 215578:ESOMN_RS02270
uniprot id: A0A2K8P1D7
names: Similarity
messages: Belongs to the DprA/Smf family.

215578:ESOMN RS00790
gene id: 215578:ESOMN_RS00790
uniprot id: A0A2K8NXS6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

215578:ESOMN RS03560
gene id: 215578:ESOMN_RS03560
uniprot id: A0A2K8NZ19
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

215578:ESOMN RS02770
gene id: 215578:ESOMN_RS02770
uniprot id: A0A2K8NYK9
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

215578:ESOMN RS02810
gene id: 215578:ESOMN_RS02810
uniprot id: A0A2K8NYM8
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

215578:ESOMN RS03270
gene id: 215578:ESOMN_RS03270
uniprot id: A0A2K8NZN2
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

215578:ESOMN RS00650
gene id: 215578:ESOMN_RS00650
uniprot id: A0A2K8NY82
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

215578:ESOMN RS01180
gene id: 215578:ESOMN_RS01180
uniprot id: A0A2K8NYI7
names: Function
names: Similarity
messages: Belongs to the UPF0122 family.
messages: Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein.

215578:ESOMN RS01960
gene id: 215578:ESOMN_RS01960
uniprot id: A0A2K8NY61
names: Similarity
messages: Belongs to the XseB family.

215578:ESOMN RS01475
gene id: 215578:ESOMN_RS01475
uniprot id: A0A2K8NXW1
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

215578:ESOMN RS00420
gene id: 215578:ESOMN_RS00420
uniprot id: A0A2K8P0E2
names: Subcellular Location Annotation
messages: Membrane

215578:ESOMN RS00710
gene id: 215578:ESOMN_RS00710
uniprot id: A0A2K8NZ86
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

215578:ESOMN RS01625
gene id: 215578:ESOMN_RS01625
uniprot id: A0A2K8NY32
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

215578:ESOMN RS01900
gene id: 215578:ESOMN_RS01900
uniprot id: A0A2K8NY49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0154 family.
messages: Membrane

215578:ESOMN RS01825
gene id: 215578:ESOMN_RS01825
uniprot id: A0A2K8NY27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

215578:ESOMN RS03740
gene id: 215578:ESOMN_RS03740
uniprot id: A0A2K8P254
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

215578:ESOMN RS02070
gene id: 215578:ESOMN_RS02070
uniprot id: A0A2K8NY77
names: Subcellular Location Annotation
messages: Membrane

215578:ESOMN RS02620
gene id: 215578:ESOMN_RS02620
uniprot id: A0A2K8P1K7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

215578:ESOMN RS02890
gene id: 215578:ESOMN_RS02890
uniprot id: A0A2K8NZG8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

215578:ESOMN RS03285
gene id: 215578:ESOMN_RS03285
uniprot id: A0A2K8NYW0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

215578:ESOMN RS01700
gene id: 215578:ESOMN_RS01700
uniprot id: A0A2K8P131
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Could methylate the ribose at the nucleotide 34 wobble position in tRNA.
messages: Cytoplasm

215578:ESOMN RS03400
gene id: 215578:ESOMN_RS03400
uniprot id: A0A2K8P1Z2
names: Similarity
messages: Belongs to the HPrK/P family.

215578:ESOMN RS01070
gene id: 215578:ESOMN_RS01070
uniprot id: A0A2K8NXN2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

215578:ESOMN RS01390
gene id: 215578:ESOMN_RS01390
uniprot id: A0A2K8NYM3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

215578:ESOMN RS02285
gene id: 215578:ESOMN_RS02285
uniprot id: A0A2K8NYK6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.
messages: Cytoplasm
messages: Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity.

215578:ESOMN RS02140
gene id: 215578:ESOMN_RS02140
uniprot id: A0A2K8NZ13
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

215578:ESOMN RS02110
gene id: 215578:ESOMN_RS02110
uniprot id: A0A2K8NY91
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

215578:ESOMN RS00150
gene id: 215578:ESOMN_RS00150
uniprot id: A0A2K8NXA9
names: Subcellular Location Annotation
messages: Membrane

215578:ESOMN RS01815
gene id: 215578:ESOMN_RS01815
uniprot id: A0A2K8P1F6
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

215578:ESOMN RS02635
gene id: 215578:ESOMN_RS02635
uniprot id: A0A2K8NYS1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

215578:ESOMN RS02020
gene id: 215578:ESOMN_RS02020
uniprot id: A0A2K8NY67
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

215578:ESOMN RS00120
gene id: 215578:ESOMN_RS00120
uniprot id: A0A2K8NX55
names: Similarity
names: Subunit
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
messages: Homodimer.

215578:ESOMN RS00670
gene id: 215578:ESOMN_RS00670
uniprot id: A0A2K8NXH2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

215578:ESOMN RS00720
gene id: 215578:ESOMN_RS00720
uniprot id: A0A2K8NXI6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

215578:ESOMN RS01995
gene id: 215578:ESOMN_RS01995
uniprot id: A0A2K8NYA1
names: Subcellular Location Annotation
messages: Membrane

215578:ESOMN RS02205
gene id: 215578:ESOMN_RS02205
uniprot id: A0A2K8NYB7
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

215578:ESOMN RS03145
gene id: 215578:ESOMN_RS03145
uniprot id: A0A2K8NZL3
names: Subcellular Location Annotation
messages: Membrane

215578:ESOMN RS02900
gene id: 215578:ESOMN_RS02900
uniprot id: A0A2K8P0H9
names: Similarity
messages: Belongs to the RNase H family.

215578:ESOMN RS02655
gene id: 215578:ESOMN_RS02655
uniprot id: A0A2K8NYK3
names: Similarity
messages: Belongs to the DEAD box helicase family.

215578:ESOMN RS03475
gene id: 215578:ESOMN_RS03475
uniprot id: A0A2K8NZS3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

215578:ESOMN RS01260
gene id: 215578:ESOMN_RS01260
uniprot id: A0A2K8P157
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
messages: Belongs to the azoreductase type 1 family.
messages: Binds 1 FMN per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones.

215578:ESOMN RS02375
gene id: 215578:ESOMN_RS02375
uniprot id: A0A2K8P1F7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

215578:ESOMN RS01680
gene id: 215578:ESOMN_RS01680
uniprot id: A0A2K8NY43
names: Similarity
messages: Belongs to the RutC family.

215578:ESOMN RS02730
gene id: 215578:ESOMN_RS02730
uniprot id: A0A2K8NYU2
names: Subcellular Location Annotation
messages: Membrane

215578:ESOMN RS03700
gene id: 215578:ESOMN_RS03700
uniprot id: A0A2K8P2H3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

215578:ESOMN RS00440
gene id: 215578:ESOMN_RS00440
uniprot id: A0A2K8NXA4
names: Similarity
messages: Belongs to the RpoE family.

215578:ESOMN RS01965
gene id: 215578:ESOMN_RS01965
uniprot id: A0A2K8P179
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

215578:ESOMN RS02860
gene id: 215578:ESOMN_RS02860
uniprot id: A0A2K8NYP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

215578:ESOMN RS00425
gene id: 215578:ESOMN_RS00425
uniprot id: A0A2K8NXA3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

215578:ESOMN RS03645
gene id: 215578:ESOMN_RS03645
uniprot id: A0A2K8NZ33
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

215578:ESOMN RS00755
gene id: 215578:ESOMN_RS00755
uniprot id: A0A2K8NXM2
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

215578:ESOMN RS01605
gene id: 215578:ESOMN_RS01605
uniprot id: A0A2K8P1B5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

215578:ESOMN RS03505
gene id: 215578:ESOMN_RS03505
uniprot id: A0A2K8P2D5
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

215578:ESOMN RS03265
gene id: 215578:ESOMN_RS03265
uniprot id: A0A2K8NYW1
names: Subcellular Location Annotation
messages: Cytoplasm

215578:ESOMN RS00170
gene id: 215578:ESOMN_RS00170
uniprot id: A0A2K8P094
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

215578:ESOMN RS00055
gene id: 215578:ESOMN_RS00055
uniprot id: A0A2K8NX88
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

215578:ESOMN RS00035
gene id: 215578:ESOMN_RS00035
uniprot id: A0A2K8P0H2
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.

215578:ESOMN RS02565
gene id: 215578:ESOMN_RS02565
uniprot id: A0A2K8NYI5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

215578:ESOMN RS02190
gene id: 215578:ESOMN_RS02190
uniprot id: A0A2K8NZ22
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

215578:ESOMN RS00895
gene id: 215578:ESOMN_RS00895
uniprot id: A0A2K8P0Y8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

215578:ESOMN RS02180
gene id: 215578:ESOMN_RS02180
uniprot id: A0A2K8NYI0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

215578:ESOMN RS02785
gene id: 215578:ESOMN_RS02785
uniprot id: A0A2K8NYM4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

215578:ESOMN RS00960
gene id: 215578:ESOMN_RS00960
uniprot id: A0A2K8P0Z8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

215578:ESOMN RS01610
gene id: 215578:ESOMN_RS01610
uniprot id: A0A2K8NY76
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

215578:ESOMN RS02925
gene id: 215578:ESOMN_RS02925
uniprot id: A0A2K8NYQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

215578:ESOMN RS00285
gene id: 215578:ESOMN_RS00285
uniprot id: A0A2K8NXH7
names: Subcellular Location Annotation
messages: Membrane

215578:ESOMN RS02775
gene id: 215578:ESOMN_RS02775
uniprot id: A0A2K8P1Z8
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

215578:ESOMN RS00825
gene id: 215578:ESOMN_RS00825
uniprot id: A0A2K8P0M3
names: Subcellular Location Annotation
messages: Membrane

215578:ESOMN RS01375
gene id: 215578:ESOMN_RS01375
uniprot id: A0A2K8P177
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

215578:ESOMN RS02865
gene id: 215578:ESOMN_RS02865
uniprot id: A0A2K8P1Q1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

215578:ESOMN RS01205
gene id: 215578:ESOMN_RS01205
uniprot id: A0A2K8P0T8
names: Similarity
messages: Belongs to the CutC family.

215578:ESOMN RS01770
gene id: 215578:ESOMN_RS01770
uniprot id: A0A2K8NY17
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family.

215578:ESOMN RS02145
gene id: 215578:ESOMN_RS02145
uniprot id: A0A2K8NYD4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

215578:ESOMN RS02575
gene id: 215578:ESOMN_RS02575
uniprot id: A0A2K8P1J7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

215578:ESOMN RS03525
gene id: 215578:ESOMN_RS03525
uniprot id: A0A2K8NZ40
names: Similarity
messages: Belongs to the LacAB/RpiB family.

215578:ESOMN RS01855
gene id: 215578:ESOMN_RS01855
uniprot id: A0A2K8P160
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

215578:ESOMN RS02735
gene id: 215578:ESOMN_RS02735
uniprot id: A0A2K8NYL5
names: Cofactor
messages: Binds 1 Mg(2+) ion per trimer.

215578:ESOMN RS03640
gene id: 215578:ESOMN_RS03640
uniprot id: A0A2K8P243
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

215578:ESOMN RS02345
gene id: 215578:ESOMN_RS02345
uniprot id: A0A2K8NYC9
names: Subcellular Location Annotation
messages: Cytoplasm

215578:ESOMN RS00500
gene id: 215578:ESOMN_RS00500
uniprot id: A0A2K8NXH3
names: Function
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

215578:ESOMN RS03470
gene id: 215578:ESOMN_RS03470
uniprot id: A0A2K8NZ03
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

215578:ESOMN RS00760
gene id: 215578:ESOMN_RS00760
uniprot id: A0A2K8NZ97
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.
messages: Cytoplasm
messages: Monomer.

215578:ESOMN RS00495
gene id: 215578:ESOMN_RS00495
uniprot id: A0A2K8NY52
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

215578:ESOMN RS00340
gene id: 215578:ESOMN_RS00340
uniprot id: A0A2K8NX83
names: Subcellular Location Annotation
messages: Membrane

215578:ESOMN RS02520
gene id: 215578:ESOMN_RS02520
uniprot id: A0A2K8NYH8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

215578:ESOMN RS01490
gene id: 215578:ESOMN_RS01490
uniprot id: A0A2K8NXW4
names: Subcellular Location Annotation
messages: Membrane

215578:ESOMN RS03380
gene id: 215578:ESOMN_RS03380
uniprot id: A0A2K8NZ09
names: Function
names: Similarity
messages: Belongs to the WhiA family.
messages: Involved in cell division and chromosome segregation.

215578:ESOMN RS02065
gene id: 215578:ESOMN_RS02065
uniprot id: A0A2K8P198
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

215578:ESOMN RS00865
gene id: 215578:ESOMN_RS00865
uniprot id: A0A2K8NZB3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

215578:ESOMN RS02715
gene id: 215578:ESOMN_RS02715
uniprot id: A0A2K8P1M3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

215578:ESOMN RS02550
gene id: 215578:ESOMN_RS02550
uniprot id: A0A2K8NZ94
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

215578:ESOMN RS00615
gene id: 215578:ESOMN_RS00615
uniprot id: A0A2K8NXG3
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

215578:ESOMN RS01745
gene id: 215578:ESOMN_RS01745
uniprot id: A0A2K8NY20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uridine kinase family.
messages: Cytoplasm

215578:ESOMN RS01095
gene id: 215578:ESOMN_RS01095
uniprot id: A0A2K8NXQ3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

215578:ESOMN RS03870
gene id: 215578:ESOMN_RS03870
uniprot id: A0A2K8NYS7
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

215578:ESOMN RS03785
gene id: 215578:ESOMN_RS03785
uniprot id: A0A2K8NZ58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OXA1/ALB3/YidC family.
messages: Cell membrane
messages: Membrane

215578:ESOMN RS00985
gene id: 215578:ESOMN_RS00985
uniprot id: A0A2K8NZD4
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.

215578:ESOMN RS00805
gene id: 215578:ESOMN_RS00805
uniprot id: A0A2K8NXN3
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

215578:ESOMN RS01140
gene id: 215578:ESOMN_RS01140
uniprot id: A0A2K8NZG5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

215578:ESOMN RS00845
gene id: 215578:ESOMN_RS00845
uniprot id: A0A2K8NXJ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

215578:ESOMN RS01210
gene id: 215578:ESOMN_RS01210
uniprot id: A0A2K8NXR0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmG family. TrmFO subfamily.
messages: Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
messages: Cytoplasm

215578:ESOMN RS00115
gene id: 215578:ESOMN_RS00115
uniprot id: A0A2K8NX65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family.
messages: Membrane

215578:ESOMN RS00350
gene id: 215578:ESOMN_RS00350
uniprot id: A0A2K8NXE4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

215578:ESOMN RS01775
gene id: 215578:ESOMN_RS01775
uniprot id: A0A2K8NYU3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type II topoisomerase family. ParE type 2 subfamily.
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

215578:ESOMN RS03480
gene id: 215578:ESOMN_RS03480
uniprot id: A0A2K8NZ30
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

215578:ESOMN RS01940
gene id: 215578:ESOMN_RS01940
uniprot id: A0A2K8NYX2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AP endonuclease 2 family.
messages: Binds 3 Zn(2+) ions.
messages: Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.

215578:ESOMN RS02935
gene id: 215578:ESOMN_RS02935
uniprot id: A0A2K8NYQ5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

215578:ESOMN RS03865
gene id: 215578:ESOMN_RS03865
uniprot id: A0A2K8P0L2
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

215578:ESOMN RS00265
gene id: 215578:ESOMN_RS00265
uniprot id: A0A2K8NX84
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

215578:ESOMN RS01280
gene id: 215578:ESOMN_RS01280
uniprot id: A0A2K8NXX1
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.

215578:ESOMN RS03665
gene id: 215578:ESOMN_RS03665
uniprot id: A0A2K8NZW3
names: Subcellular Location Annotation
messages: Membrane

215578:ESOMN RS02795
gene id: 215578:ESOMN_RS02795
uniprot id: A0A2K8NYQ4
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

215578:ESOMN RS01635
gene id: 215578:ESOMN_RS01635
uniprot id: A0A2K8NXZ9
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

215578:ESOMN RS03115
gene id: 215578:ESOMN_RS03115
uniprot id: A0A2K8NYU0
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

215578:ESOMN RS01860
gene id: 215578:ESOMN_RS01860
uniprot id: A0A2K8NY38
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvB family.
messages: Forms a complex with RuvA.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.

215578:ESOMN RS03565
gene id: 215578:ESOMN_RS03565
uniprot id: A0A2K8NZU3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

215578:ESOMN RS02880
gene id: 215578:ESOMN_RS02880
uniprot id: A0A2K8NYX7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

215578:ESOMN RS00225
gene id: 215578:ESOMN_RS00225
uniprot id: A0A2K8NX67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

215578:ESOMN RS01765
gene id: 215578:ESOMN_RS01765
uniprot id: A0A2K8NYA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family.
messages: Membrane

215578:ESOMN RS03705
gene id: 215578:ESOMN_RS03705
uniprot id: A0A2K8NZC9
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

215578:ESOMN RS01695
gene id: 215578:ESOMN_RS01695
uniprot id: A0A2K8NY10
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

215578:ESOMN RS01665
gene id: 215578:ESOMN_RS01665
uniprot id: A0A2K8NY86
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

215578:ESOMN RS03570
gene id: 215578:ESOMN_RS03570
uniprot id: A0A2K8NZ49
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family. N(4) subfamily.

215578:ESOMN RS01510
gene id: 215578:ESOMN_RS01510
uniprot id: A0A2K8NXX9
names: Similarity
messages: Belongs to the dihydrofolate reductase family.

215578:ESOMN RS00655
gene id: 215578:ESOMN_RS00655
uniprot id: A0A2K8NXK1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

215578:ESOMN RS03315
gene id: 215578:ESOMN_RS03315
uniprot id: A0A2K8NYX0
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

215578:ESOMN RS02085
gene id: 215578:ESOMN_RS02085
uniprot id: A0A2K8NY78
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

215578:ESOMN RS00165
gene id: 215578:ESOMN_RS00165
uniprot id: A0A2K8NX64
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

215578:ESOMN RS03395
gene id: 215578:ESOMN_RS03395
uniprot id: A0A2K8NYX5
names: Similarity
messages: Belongs to the Lgt family.

215578:ESOMN RS02280
gene id: 215578:ESOMN_RS02280
uniprot id: A0A2K8P1N7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

215578:ESOMN RS00355
gene id: 215578:ESOMN_RS00355
uniprot id: A0A2K8NZ17
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

215578:ESOMN RS03765
gene id: 215578:ESOMN_RS03765
uniprot id: A0A2K8NZY1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

215578:ESOMN RS02570
gene id: 215578:ESOMN_RS02570
uniprot id: A0A2K8NYI8
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

215578:ESOMN RS03225
gene id: 215578:ESOMN_RS03225
uniprot id: A0A2K8NYY2
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

215578:ESOMN RS03235
gene id: 215578:ESOMN_RS03235
uniprot id: A0A2K8NYV0
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

215578:ESOMN RS02325
gene id: 215578:ESOMN_RS02325
uniprot id: A0A2K8NYC5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase Y family.
messages: Cell membrane
messages: Endoribonuclease that initiates mRNA decay.

215578:ESOMN RS03790
gene id: 215578:ESOMN_RS03790
uniprot id: A0A2K8NZ53
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

215578:ESOMN RS02055
gene id: 215578:ESOMN_RS02055
uniprot id: A0A2K8NY81
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

215578:ESOMN RS01345
gene id: 215578:ESOMN_RS01345
uniprot id: A0A2K8NXY0
names: Subcellular Location Annotation
messages: Membrane

215578:ESOMN RS00090
gene id: 215578:ESOMN_RS00090
uniprot id: A0A2K8NXD8
names: Subcellular Location Annotation
messages: Membrane

215578:ESOMN RS02120
gene id: 215578:ESOMN_RS02120
uniprot id: A0A2K8NY87
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

215578:ESOMN RS01550
gene id: 215578:ESOMN_RS01550
uniprot id: A0A2K8NXX2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

215578:ESOMN RS01215
gene id: 215578:ESOMN_RS01215
uniprot id: A0A2K8P146
names: Cofactor
messages: Binds 1 zinc ion per subunit.

215578:ESOMN RS01990
gene id: 215578:ESOMN_RS01990
uniprot id: A0A2K8NYY3
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

215578:ESOMN RS02930
gene id: 215578:ESOMN_RS02930
uniprot id: A0A2K8P227
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIIB subfamily.
messages: Cell inner membrane
messages: Mediates magnesium influx to the cytosol.

215578:ESOMN RS02805
gene id: 215578:ESOMN_RS02805
uniprot id: A0A2K8NYM9
names: Similarity
messages: Belongs to the phosphate acetyltransferase and butyryltransferase family.

215578:ESOMN RS03585
gene id: 215578:ESOMN_RS03585
uniprot id: A0A2K8NZ11
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

215578:ESOMN RS00385
gene id: 215578:ESOMN_RS00385
uniprot id: A0A2K8NXJ5
names: Similarity
messages: Belongs to the carbamate kinase family.

215578:ESOMN RS01820
gene id: 215578:ESOMN_RS01820
uniprot id: A0A2K8NYB2
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

215578:ESOMN RS00965
gene id: 215578:ESOMN_RS00965
uniprot id: A0A2K8NXV4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

215578:ESOMN RS03590
gene id: 215578:ESOMN_RS03590
uniprot id: A0A2K8P231
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

215578:ESOMN RS03510
gene id: 215578:ESOMN_RS03510
uniprot id: A0A2K8NZ91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

215578:ESOMN RS03030
gene id: 215578:ESOMN_RS03030
uniprot id: A0A2K8NYZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

215578:ESOMN RS00570
gene id: 215578:ESOMN_RS00570
uniprot id: A0A2K8P0H3
names: Subcellular Location Annotation
messages: Membrane

215578:ESOMN RS00735
gene id: 215578:ESOMN_RS00735
uniprot id: A0A2K8P0V9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

215578:ESOMN RS03755
gene id: 215578:ESOMN_RS03755
uniprot id: A0A2K8NZD8
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

215578:ESOMN RS02155
gene id: 215578:ESOMN_RS02155
uniprot id: A0A2K8NYA7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

215578:ESOMN RS02540
gene id: 215578:ESOMN_RS02540
uniprot id: A0A2K8NYQ7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

215578:ESOMN RS02260
gene id: 215578:ESOMN_RS02260
uniprot id: A0A2K8NYC6
names: Similarity
messages: Belongs to the ABC transporter superfamily.

215578:ESOMN RS02680
gene id: 215578:ESOMN_RS02680
uniprot id: A0A2K8NYT0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-3 family.
messages: Cytoplasm
messages: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
messages: Monomer.

215578:ESOMN RS02525
gene id: 215578:ESOMN_RS02525
uniprot id: A0A2K8P1I7
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

215578:ESOMN RS00565
gene id: 215578:ESOMN_RS00565
uniprot id: A0A2K8NXF2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

215578:ESOMN RS01800
gene id: 215578:ESOMN_RS01800
uniprot id: A0A2K8NY30
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

215578:ESOMN RS02815
gene id: 215578:ESOMN_RS02815
uniprot id: A0A2K8P1P3
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

215578:ESOMN RS00705
gene id: 215578:ESOMN_RS00705
uniprot id: A0A2K8NXL1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

215578:ESOMN RS01840
gene id: 215578:ESOMN_RS01840
uniprot id: A0A2K8NZU8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LDH/MDH superfamily. LDH family.
messages: Catalyzes the conversion of lactate to pyruvate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

215578:ESOMN RS00765
gene id: 215578:ESOMN_RS00765
uniprot id: A0A2K8NXJ0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

215578:ESOMN RS00680
gene id: 215578:ESOMN_RS00680
uniprot id: A0A2K8NXF7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

215578:ESOMN RS03615
gene id: 215578:ESOMN_RS03615
uniprot id: A0A2K8NZV3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

215578:ESOMN RS02460
gene id: 215578:ESOMN_RS02460
uniprot id: A0A2K8P082
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

215578:ESOMN RS00575
gene id: 215578:ESOMN_RS00575
uniprot id: A0A2K8NXD5
names: Similarity
messages: Belongs to the peptidase M17 family.

215578:ESOMN RS00380
gene id: 215578:ESOMN_RS00380
uniprot id: A0A2K8P0N9
names: Subcellular Location Annotation
messages: Membrane

215578:ESOMN RS00975
gene id: 215578:ESOMN_RS00975
uniprot id: A0A2K8NYE5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThiI family.
messages: Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
messages: Cytoplasm

215578:ESOMN RS02060
gene id: 215578:ESOMN_RS02060
uniprot id: A0A2K8NY79
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

215578:ESOMN RS00205
gene id: 215578:ESOMN_RS00205
uniprot id: A0A2K8NYY8
names: Activity Regulation
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.

215578:ESOMN RS00125
gene id: 215578:ESOMN_RS00125
uniprot id: A0A2K8NX46
names: Similarity
messages: Belongs to the phosphohexose mutase family.

215578:ESOMN RS02370
gene id: 215578:ESOMN_RS02370
uniprot id: A0A2K8NYE8
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

215578:ESOMN RS00460
gene id: 215578:ESOMN_RS00460
uniprot id: A0A2K8NXD3
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

215578:ESOMN RS00050
gene id: 215578:ESOMN_RS00050
uniprot id: A0A2K8NXW8
names: Similarity
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.

215578:ESOMN RS01120
gene id: 215578:ESOMN_RS01120
uniprot id: A0A2K8NXY6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

215578:ESOMN RS02760
gene id: 215578:ESOMN_RS02760
uniprot id: A0A2K8NYL9
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

215578:ESOMN RS03795
gene id: 215578:ESOMN_RS03795
uniprot id: A0A2K8P264
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

215578:ESOMN RS00810
gene id: 215578:ESOMN_RS00810
uniprot id: A0A2K8NZA5
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

215578:ESOMN RS00320
gene id: 215578:ESOMN_RS00320
uniprot id: A0A2K8P0C2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

215578:ESOMN RS00020
gene id: 215578:ESOMN_RS00020
uniprot id: A0A2K8NX33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm

215578:ESOMN RS01735
gene id: 215578:ESOMN_RS01735
uniprot id: A0A2K8NZS8
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

215578:ESOMN RS03655
gene id: 215578:ESOMN_RS03655
uniprot id: A0A2K8NZB8
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

215578:ESOMN RS00800
gene id: 215578:ESOMN_RS00800
uniprot id: A0A2K8NYB3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

215578:ESOMN RS00145
gene id: 215578:ESOMN_RS00145
uniprot id: A0A2K8NXY8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

215578:ESOMN RS01125
gene id: 215578:ESOMN_RS01125
uniprot id: A0A2K8NXP2
names: Similarity
messages: Belongs to the asp23 family.

215578:ESOMN RS03600
gene id: 215578:ESOMN_RS03600
uniprot id: A0A2K8P2F4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

215578:ESOMN RS02845
gene id: 215578:ESOMN_RS02845
uniprot id: A0A2K8NYR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family.
messages: Membrane

215578:ESOMN RS03460
gene id: 215578:ESOMN_RS03460
uniprot id: A0A2K8P2C5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

215578:ESOMN RS00375
gene id: 215578:ESOMN_RS00375
uniprot id: A0A2K8NX94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

215578:ESOMN RS02315
gene id: 215578:ESOMN_RS02315
uniprot id: A0A2K8NYD8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

215578:ESOMN RS00230
gene id: 215578:ESOMN_RS00230
uniprot id: A0A2K8P0K8
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

215578:ESOMN RS00840
gene id: 215578:ESOMN_RS00840
uniprot id: A0A2K8NXT6
names: Subcellular Location Annotation
messages: Membrane

215578:ESOMN RS02780
gene id: 215578:ESOMN_RS02780
uniprot id: A0A2K8NYV1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

215578:ESOMN RS02470
gene id: 215578:ESOMN_RS02470
uniprot id: A0A2K8NYG8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

215578:ESOMN RS00025
gene id: 215578:ESOMN_RS00025
uniprot id: A0A2K8P064
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ribonuclease M5 family.
messages: Cytoplasm
messages: Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step.

215578:ESOMN RS00190
gene id: 215578:ESOMN_RS00190
uniprot id: A0A2K8NX52
names: Similarity
messages: Belongs to the pyrroline-5-carboxylate reductase family.

215578:ESOMN RS01485
gene id: 215578:ESOMN_RS01485
uniprot id: A0A2K8NY56
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

215578:ESOMN RS01480
gene id: 215578:ESOMN_RS01480
uniprot id: A0A2K8P195
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

215578:ESOMN RS00095
gene id: 215578:ESOMN_RS00095
uniprot id: A0A2K8NX32
names: Subcellular Location Annotation
messages: Membrane

215578:ESOMN RS00305
gene id: 215578:ESOMN_RS00305
uniprot id: A0A2K8NZ07
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

215578:ESOMN RS00630
gene id: 215578:ESOMN_RS00630
uniprot id: A0A2K8NXE7
names: Subcellular Location Annotation
messages: Membrane

215578:ESOMN RS00490
gene id: 215578:ESOMN_RS00490
uniprot id: A0A2K8NXB6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.

215578:ESOMN RS00325
gene id: 215578:ESOMN_RS00325
uniprot id: A0A2K8NX85
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

215578:ESOMN RS00560
gene id: 215578:ESOMN_RS00560
uniprot id: A0A2K8NXF3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

215578:ESOMN RS02850
gene id: 215578:ESOMN_RS02850
uniprot id: A0A2K8P0G7
names: Similarity
messages: Belongs to the pyruvate kinase family.

215578:ESOMN RS01810
gene id: 215578:ESOMN_RS01810
uniprot id: A0A2K8NY28
names: Subcellular Location Annotation
messages: Membrane

215578:ESOMN RS02105
gene id: 215578:ESOMN_RS02105
uniprot id: A0A2K8NY92
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of glycine to tRNA(Gly).
messages: Cytoplasm
messages: Homodimer.

215578:ESOMN RS02365
gene id: 215578:ESOMN_RS02365
uniprot id: A0A2K8NYE7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

215578:ESOMN RS01075
gene id: 215578:ESOMN_RS01075
uniprot id: A0A2K8NYG6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Cytoplasm
messages: Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.

215578:ESOMN RS02855
gene id: 215578:ESOMN_RS02855
uniprot id: A0A2K8NYN9
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

215578:ESOMN RS03055
gene id: 215578:ESOMN_RS03055
uniprot id: A0A2K8NYS5
names: Subcellular Location Annotation
messages: Membrane

215578:ESOMN RS00395
gene id: 215578:ESOMN_RS00395
uniprot id: A0A2K8NY36
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

215578:ESOMN RS02950
gene id: 215578:ESOMN_RS02950
uniprot id: A0A2K8P0J9
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
messages: Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

215578:ESOMN RS03420
gene id: 215578:ESOMN_RS03420
uniprot id: A0A2K8NYZ1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

215578:ESOMN RS00345
gene id: 215578:ESOMN_RS00345
uniprot id: A0A2K8NY26
names: Subcellular Location Annotation
messages: Membrane

215578:ESOMN RS02590
gene id: 215578:ESOMN_RS02590
uniprot id: A0A2K8NYI4
names: Function
names: Similarity
messages: Belongs to the NrdI family.
messages: Probably involved in ribonucleotide reductase function.

215578:ESOMN RS00750
gene id: 215578:ESOMN_RS00750
uniprot id: A0A2K8NYA5
names: Function
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.
messages: Catalyzes the ATP-dependent phosphorylation of fructose-l-phosphate to fructose-l,6-bisphosphate.

215578:ESOMN RS02840
gene id: 215578:ESOMN_RS02840
uniprot id: A0A2K8NZF7
names: Function
names: Similarity
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.

215578:ESOMN RS02200
gene id: 215578:ESOMN_RS02200
uniprot id: A0A2K8P027
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

215578:ESOMN RS02230
gene id: 215578:ESOMN_RS02230
uniprot id: A0A2K8NYJ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

215578:ESOMN RS02195
gene id: 215578:ESOMN_RS02195
uniprot id: A0A2K8NYE3
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

215578:ESOMN RS01650
gene id: 215578:ESOMN_RS01650
uniprot id: A0A2K8NXZ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

215578:ESOMN RS03195
gene id: 215578:ESOMN_RS03195
uniprot id: A0A2K8P1V7
names: Subcellular Location Annotation
messages: Membrane

215578:ESOMN RS02615
gene id: 215578:ESOMN_RS02615
uniprot id: A0A2K8NYJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

215578:ESOMN RS00010
gene id: 215578:ESOMN_RS00010
uniprot id: A0A2K8NYU8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

215578:ESOMN RS00675
gene id: 215578:ESOMN_RS00675
uniprot id: A0A2K8P0J3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

215578:ESOMN RS01495
gene id: 215578:ESOMN_RS01495
uniprot id: A0A2K8NYP3
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

215578:ESOMN RS03190
gene id: 215578:ESOMN_RS03190
uniprot id: A0A2K8NYT8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

215578:ESOMN RS02125
gene id: 215578:ESOMN_RS02125
uniprot id: A0A2K8P1L2
names: Similarity
messages: Belongs to the ABC transporter superfamily.

215578:ESOMN RS00925
gene id: 215578:ESOMN_RS00925
uniprot id: A0A2K8NZC5
names: Similarity
messages: Belongs to the Fur family.

215578:ESOMN RS03465
gene id: 215578:ESOMN_RS03465
uniprot id: A0A2K8NZ81
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

215578:ESOMN RS03320
gene id: 215578:ESOMN_RS03320
uniprot id: A0A2K8NZP3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

215578:ESOMN RS02395
gene id: 215578:ESOMN_RS02395
uniprot id: A0A2K8NYD9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

215578:ESOMN RS00685
gene id: 215578:ESOMN_RS00685
uniprot id: A0A2K8P0U8
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

215578:ESOMN RS00585
gene id: 215578:ESOMN_RS00585
uniprot id: A0A2K8NXN4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M3B family.
messages: Binds 1 zinc ion.
messages: Has oligopeptidase activity and degrades a variety of small bioactive peptides.

215578:ESOMN RS02350
gene id: 215578:ESOMN_RS02350
uniprot id: A0A2K8NZ52
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecU family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

215578:ESOMN RS02415
gene id: 215578:ESOMN_RS02415
uniprot id: A0A2K8NYF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

215578:ESOMN RS01045
gene id: 215578:ESOMN_RS01045
uniprot id: A0A2K8NXP5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

215578:ESOMN RS03210
gene id: 215578:ESOMN_RS03210
uniprot id: A0A2K8NZ35
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

215578:ESOMN RS02185
gene id: 215578:ESOMN_RS02185
uniprot id: A0A2K8NY99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Membrane

215578:ESOMN RS02825
gene id: 215578:ESOMN_RS02825
uniprot id: A0A2K8P209
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

215578:ESOMN RS00990
gene id: 215578:ESOMN_RS00990
uniprot id: A0A2K8NXN1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

215578:ESOMN RS02100
gene id: 215578:ESOMN_RS02100
uniprot id: A0A2K8P002
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

215578:ESOMN RS00770
gene id: 215578:ESOMN_RS00770
uniprot id: A0A2K8NXJ6
names: Subcellular Location Annotation
messages: Membrane

215578:ESOMN RS02800
gene id: 215578:ESOMN_RS02800
uniprot id: A0A2K8P0F8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

215578:ESOMN RS03370
gene id: 215578:ESOMN_RS03370
uniprot id: A0A2K8NYY1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Membrane

215578:ESOMN RS01895
gene id: 215578:ESOMN_RS01895
uniprot id: A0A2K8NZV8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

215578:ESOMN RS00455
gene id: 215578:ESOMN_RS00455
uniprot id: A0A2K8NZ37
names: Subcellular Location Annotation
messages: Membrane

215578:ESOMN RS02255
gene id: 215578:ESOMN_RS02255
uniprot id: A0A2K8P039
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmG family. TrmFO subfamily.
messages: Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
messages: Cytoplasm

215578:ESOMN RS03450
gene id: 215578:ESOMN_RS03450
uniprot id: A0A2K8P202
names: Similarity
messages: Belongs to the ATPase epsilon chain family.

215578:ESOMN RS01005
gene id: 215578:ESOMN_RS01005
uniprot id: A0A2K8NXM0
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

215578:ESOMN RS00795
gene id: 215578:ESOMN_RS00795
uniprot id: A0A2K8NXI0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

215578:ESOMN RS02660
gene id: 215578:ESOMN_RS02660
uniprot id: A0A2K8NYK8
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

215578:ESOMN RS00030
gene id: 215578:ESOMN_RS00030
uniprot id: A0A2K8NX27
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

215578:ESOMN RS03240
gene id: 215578:ESOMN_RS03240
uniprot id: A0A2K8NYU7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

215578:ESOMN RS02675
gene id: 215578:ESOMN_RS02675
uniprot id: A0A2K8P1X6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

215578:ESOMN RS03675
gene id: 215578:ESOMN_RS03675
uniprot id: A0A2K8P0X3
names: Subcellular Location Annotation
messages: Membrane

215578:ESOMN RS00365
gene id: 215578:ESOMN_RS00365
uniprot id: A0A2K8NXB1
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

215578:ESOMN RS00430
gene id: 215578:ESOMN_RS00430
uniprot id: A0A2K8P0P9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

215578:ESOMN RS00900
gene id: 215578:ESOMN_RS00900
uniprot id: A0A2K8NXU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

215578:ESOMN RS02875
gene id: 215578:ESOMN_RS02875
uniprot id: A0A2K8P219
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

215578:ESOMN RS03035
gene id: 215578:ESOMN_RS03035
uniprot id: A0A2K8NYS3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

215578:ESOMN RS00640
gene id: 215578:ESOMN_RS00640
uniprot id: A0A2K8NXP4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

215578:ESOMN RS01290
gene id: 215578:ESOMN_RS01290
uniprot id: A0A2K8NXT9
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

215578:ESOMN RS00465
gene id: 215578:ESOMN_RS00465
uniprot id: A0A2K8NXD2
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

215578:ESOMN RS00715
gene id: 215578:ESOMN_RS00715
uniprot id: A0A2K8NXI2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

215578:ESOMN RS03880
gene id: 215578:ESOMN_RS03880
uniprot id: A0A2K8P221
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

215578:ESOMN RS02005
gene id: 215578:ESOMN_RS02005
uniprot id: A0A2K8NY69
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

215578:ESOMN RS00850
gene id: 215578:ESOMN_RS00850
uniprot id: A0A2K8NYC2
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

215578:ESOMN RS01200
gene id: 215578:ESOMN_RS01200
uniprot id: A0A2K8NXS5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

215578:ESOMN RS00445
gene id: 215578:ESOMN_RS00445
uniprot id: A0A2K8NY45
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

215578:ESOMN RS00700
gene id: 215578:ESOMN_RS00700
uniprot id: A0A2K8NY90
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

215578:ESOMN RS01505
gene id: 215578:ESOMN_RS01505
uniprot id: A0A2K8NZN6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

215578:ESOMN RS01645
gene id: 215578:ESOMN_RS01645
uniprot id: A0A2K8P120
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

215578:ESOMN RS02360
gene id: 215578:ESOMN_RS02360
uniprot id: A0A2K8P060
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

215578:ESOMN RS00665
gene id: 215578:ESOMN_RS00665
uniprot id: A0A2K8NXH4
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

215578:ESOMN RS02050
gene id: 215578:ESOMN_RS02050
uniprot id: A0A2K8NZZ2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

215578:ESOMN RS03650
gene id: 215578:ESOMN_RS03650
uniprot id: A0A2K8P2G4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

215578:ESOMN RS02165
gene id: 215578:ESOMN_RS02165
uniprot id: A0A2K8P1C0
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

215578:ESOMN RS03580
gene id: 215578:ESOMN_RS03580
uniprot id: A0A2K8NZ18
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

215578:ESOMN RS01560
gene id: 215578:ESOMN_RS01560
uniprot id: A0A2K8NY65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

215578:ESOMN RS03620
gene id: 215578:ESOMN_RS03620
uniprot id: A0A2K8NZ60
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

215578:ESOMN RS01955
gene id: 215578:ESOMN_RS01955
uniprot id: A0A2K8NY59
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

215578:ESOMN RS03390
gene id: 215578:ESOMN_RS03390
uniprot id: A0A2K8NYY0
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Homodimer.

215578:ESOMN RS02580
gene id: 215578:ESOMN_RS02580
uniprot id: A0A2K8P1V3
names: Similarity
messages: Belongs to the FtsK/SpoIIIE/SftA family.

215578:ESOMN RS02475
gene id: 215578:ESOMN_RS02475
uniprot id: A0A2K8P1H7
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

215578:ESOMN RS03875
gene id: 215578:ESOMN_RS03875
uniprot id: A0A2K8NZ00
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

215578:ESOMN RS02290
gene id: 215578:ESOMN_RS02290
uniprot id: A0A2K8NYB9
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

215578:ESOMN RS03445
gene id: 215578:ESOMN_RS03445
uniprot id: A0A2K8NYY4
names: Subcellular Location Annotation
messages: Membrane

215578:ESOMN RS00040
gene id: 215578:ESOMN_RS00040
uniprot id: A0A2K8NXD0
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

215578:ESOMN RS02695
gene id: 215578:ESOMN_RS02695
uniprot id: A0A2K8NYN5
names: Subcellular Location Annotation
messages: Membrane

215578:ESOMN RS00605
gene id: 215578:ESOMN_RS00605
uniprot id: A0A2K8NXJ1
names: Similarity
messages: Belongs to the ABC transporter superfamily.

215578:ESOMN RS02645
gene id: 215578:ESOMN_RS02645
uniprot id: A0A2K8NZB4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

215578:ESOMN RS01135
gene id: 215578:ESOMN_RS01135
uniprot id: A0A2K8NXU0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

215578:ESOMN RS00785
gene id: 215578:ESOMN_RS00785
uniprot id: A0A2K8P0W9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

215578:ESOMN RS01780
gene id: 215578:ESOMN_RS01780
uniprot id: A0A2K8NY63
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 2 subfamily.
messages: Cell membrane
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

215578:ESOMN RS00725
gene id: 215578:ESOMN_RS00725
uniprot id: A0A2K8P0K4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

215578:ESOMN RS01710
gene id: 215578:ESOMN_RS01710
uniprot id: A0A2K8P1D2
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

215578:ESOMN RS01675
gene id: 215578:ESOMN_RS01675
uniprot id: A0A2K8NYS0
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

215578:ESOMN RS03455
gene id: 215578:ESOMN_RS03455
uniprot id: A0A2K8NYZ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

215578:ESOMN RS02945
gene id: 215578:ESOMN_RS02945
uniprot id: A0A2K8NYT1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

215578:ESOMN RS03260
gene id: 215578:ESOMN_RS03260
uniprot id: A0A2K8NZ45
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.

215578:ESOMN RS03415
gene id: 215578:ESOMN_RS03415
uniprot id: A0A2K8NZ70
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

215578:ESOMN RS00775
gene id: 215578:ESOMN_RS00775
uniprot id: A0A2K8P0L4
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

215578:ESOMN RS00530
gene id: 215578:ESOMN_RS00530
uniprot id: A0A2K8P0S0
names: Subcellular Location Annotation
messages: Membrane

215578:ESOMN RS00250
gene id: 215578:ESOMN_RS00250
uniprot id: A0A2K8NXC7
names: Subcellular Location Annotation
messages: Membrane

215578:ESOMN RS03090
gene id: 215578:ESOMN_RS03090
uniprot id: A0A2K8NYW7
names: Similarity
messages: Belongs to the thioredoxin family.

215578:ESOMN RS01630
gene id: 215578:ESOMN_RS01630
uniprot id: A0A2K8NZQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

215578:ESOMN RS01100
gene id: 215578:ESOMN_RS01100
uniprot id: A0A2K8P0R9
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.

215578:ESOMN RS03275
gene id: 215578:ESOMN_RS03275
uniprot id: A0A2K8NYZ4
names: Subcellular Location Annotation
messages: Membrane

215578:ESOMN RS02075
gene id: 215578:ESOMN_RS02075
uniprot id: A0A2K8P1K3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

215578:ESOMN RS01360
gene id: 215578:ESOMN_RS01360
uniprot id: A0A2K8NXV3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

215578:ESOMN RS03360
gene id: 215578:ESOMN_RS03360
uniprot id: A0A2K8P2A5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

215578:ESOMN RS02305
gene id: 215578:ESOMN_RS02305
uniprot id: A0A2K8P051
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

215578:ESOMN RS00555
gene id: 215578:ESOMN_RS00555
uniprot id: A0A2K8NZ56
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

215578:ESOMN RS02895
gene id: 215578:ESOMN_RS02895
uniprot id: A0A2K8NYR8
names: Similarity
messages: Belongs to the lipase/esterase LIP3/BchO family.

215578:ESOMN RS03385
gene id: 215578:ESOMN_RS03385
uniprot id: A0A2K8P0R5
names: Similarity
messages: Belongs to the Lgt family.

215578:ESOMN RS00660
gene id: 215578:ESOMN_RS00660
uniprot id: A0A2K8NZ76
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

215578:ESOMN RS02295
gene id: 215578:ESOMN_RS02295
uniprot id: A0A2K8NZ41
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

215578:ESOMN RS00740
gene id: 215578:ESOMN_RS00740
uniprot id: A0A2K8NXR6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

215578:ESOMN RS01010
gene id: 215578:ESOMN_RS01010
uniprot id: A0A2K8P108
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

215578:ESOMN RS01355
gene id: 215578:ESOMN_RS01355
uniprot id: A0A2K8NXU9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

215578:ESOMN RS02225
gene id: 215578:ESOMN_RS02225
uniprot id: A0A2K8P1M7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
messages: Homodimer.

215578:ESOMN RS01380
gene id: 215578:ESOMN_RS01380
uniprot id: A0A2K8NY35
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

215578:ESOMN RS00195
gene id: 215578:ESOMN_RS00195
uniprot id: A0A2K8NXZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

215578:ESOMN RS00070
gene id: 215578:ESOMN_RS00070
uniprot id: A0A2K8NX43
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

215578:ESOMN RS01565
gene id: 215578:ESOMN_RS01565
uniprot id: A0A2K8NXX6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-C family. PolC subfamily.
messages: Cytoplasm
messages: Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

215578:ESOMN RS02585
gene id: 215578:ESOMN_RS02585
uniprot id: A0A2K8NYR3
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

215578:ESOMN RS02905
gene id: 215578:ESOMN_RS02905
uniprot id: A0A2K8NYP8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
messages: Consists of three domains: the N-terminal catalytic domain, the anticodon-binding domain and the C-terminal extension.
messages: Cytoplasm
messages: Homodimer.

215578:ESOMN RS00550
gene id: 215578:ESOMN_RS00550
uniprot id: A0A2K8NXI3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

215578:ESOMN RS01190
gene id: 215578:ESOMN_RS01190
uniprot id: A0A2K8NZH5
names: Similarity
messages: Belongs to the lipase/esterase LIP3/BchO family.

215578:ESOMN RS01370
gene id: 215578:ESOMN_RS01370
uniprot id: A0A2K8NXU1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

215578:ESOMN RS01305
gene id: 215578:ESOMN_RS01305
uniprot id: A0A2K8NXT2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm