2133959:D1093 RS06460
gene id: 2133959:D1093_RS06460
uniprot id: A0A5B9CXS4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

2133959:D1093 RS07030
gene id: 2133959:D1093_RS07030
uniprot id: A0A5B9CY70
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

2133959:D1093 RS05205
gene id: 2133959:D1093_RS05205
uniprot id: A0A5B9CXZ9
names: Similarity
messages: Belongs to the YkuD family.

2133959:D1093 RS01600
gene id: 2133959:D1093_RS01600
uniprot id: A0A5B9CUN8
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

2133959:D1093 RS05665
gene id: 2133959:D1093_RS05665
uniprot id: A0A5B9CY79
names: Subcellular Location Annotation
messages: Membrane

2133959:D1093 RS06075
gene id: 2133959:D1093_RS06075
uniprot id: A0A5B9CY13
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

2133959:D1093 RS07750
gene id: 2133959:D1093_RS07750
uniprot id: A0A5B9CZ98
names: Subcellular Location Annotation
messages: Membrane

2133959:D1093 RS03800
gene id: 2133959:D1093_RS03800
uniprot id: A0A5B9CWC0
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

2133959:D1093 RS03045
gene id: 2133959:D1093_RS03045
uniprot id: A0A5B9CW19
names: Similarity
messages: Belongs to the HicA mRNA interferase family.

2133959:D1093 RS03585
gene id: 2133959:D1093_RS03585
uniprot id: A0A5B9CWB4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

2133959:D1093 RS00830
gene id: 2133959:D1093_RS00830
uniprot id: A0A5B9CUQ2
names: Similarity
messages: Belongs to the TrbL/VirB6 family.

2133959:D1093 RS03725
gene id: 2133959:D1093_RS03725
uniprot id: A0A5B9CW46
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

2133959:D1093 RS00570
gene id: 2133959:D1093_RS00570
uniprot id: A0A5B9CUK4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

2133959:D1093 RS05690
gene id: 2133959:D1093_RS05690
uniprot id: A0A5B9CWR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

2133959:D1093 RS05945
gene id: 2133959:D1093_RS05945
uniprot id: A0A5B9CWT5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

2133959:D1093 RS06615
gene id: 2133959:D1093_RS06615
uniprot id: A0A5B9CYS0
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

2133959:D1093 RS06485
gene id: 2133959:D1093_RS06485
uniprot id: A0A5B9CXW9
names: Function
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

2133959:D1093 RS03655
gene id: 2133959:D1093_RS03655
uniprot id: A0A5B9CXF0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

2133959:D1093 RS01780
gene id: 2133959:D1093_RS01780
uniprot id: A0A5B9CW33
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

2133959:D1093 RS03630
gene id: 2133959:D1093_RS03630
uniprot id: A0A5B9CWJ4
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

2133959:D1093 RS06550
gene id: 2133959:D1093_RS06550
uniprot id: A0A5B9CXJ7
names: Similarity
messages: Belongs to the ABC transporter superfamily.

2133959:D1093 RS05570
gene id: 2133959:D1093_RS05570
uniprot id: A0A5B9CWL4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

2133959:D1093 RS06480
gene id: 2133959:D1093_RS06480
uniprot id: A0A5B9CYU7
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

2133959:D1093 RS00415
gene id: 2133959:D1093_RS00415
uniprot id: A0A5B9CUN6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds the 23S rRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the 50S ribosomal subunit.

2133959:D1093 RS05600
gene id: 2133959:D1093_RS05600
uniprot id: A0A5B9CX20
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

2133959:D1093 RS03640
gene id: 2133959:D1093_RS03640
uniprot id: A0A5B9CX72
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

2133959:D1093 RS01975
gene id: 2133959:D1093_RS01975
uniprot id: A0A5B9CUU6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

2133959:D1093 RS02390
gene id: 2133959:D1093_RS02390
uniprot id: A0A5B9CWE4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

2133959:D1093 RS05420
gene id: 2133959:D1093_RS05420
uniprot id: A0A5B9CYA3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

2133959:D1093 RS09325
gene id: 2133959:D1093_RS09325
uniprot id: A0A5B9CYI2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2133959:D1093 RS03620
gene id: 2133959:D1093_RS03620
uniprot id: A0A5B9CVM6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

2133959:D1093 RS06475
gene id: 2133959:D1093_RS06475
uniprot id: A0A5B9CX35
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

2133959:D1093 RS05820
gene id: 2133959:D1093_RS05820
uniprot id: A0A5B9CXD2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

2133959:D1093 RS02300
gene id: 2133959:D1093_RS02300
uniprot id: A0A5B9CWS2
names: Function
names: Similarity
messages: Belongs to the NrdI family.
messages: Probably involved in ribonucleotide reductase function.

2133959:D1093 RS02295
gene id: 2133959:D1093_RS02295
uniprot id: A0A5B9CUZ2
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Electron transport system for the ribonucleotide reductase system NrdEF.

2133959:D1093 RS00485
gene id: 2133959:D1093_RS00485
uniprot id: A0A5B9CVC5
names: Similarity
messages: Belongs to the UPF0335 family.

2133959:D1093 RS00535
gene id: 2133959:D1093_RS00535
uniprot id: A0A5B9CVD6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

2133959:D1093 RS00660
gene id: 2133959:D1093_RS00660
uniprot id: A0A5B9CUW6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division. Important for assembly or stability of the septal ring.

2133959:D1093 RS05215
gene id: 2133959:D1093_RS05215
uniprot id: A0A5B9CWD9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

2133959:D1093 RS01380
gene id: 2133959:D1093_RS01380
uniprot id: A0A5B9CUI4
names: Function
names: Subunit
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease.

2133959:D1093 RS00010
gene id: 2133959:D1093_RS00010
uniprot id: A0A5B9CUA3
names: Subcellular Location Annotation
messages: Membrane

2133959:D1093 RS04750
gene id: 2133959:D1093_RS04750
uniprot id: A0A5B9CW85
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

2133959:D1093 RS03920
gene id: 2133959:D1093_RS03920
uniprot id: A0A5B9CWG8
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2133959:D1093 RS00525
gene id: 2133959:D1093_RS00525
uniprot id: A0A5B9CUZ6
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

2133959:D1093 RS03605
gene id: 2133959:D1093_RS03605
uniprot id: A0A5B9CXD4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

2133959:D1093 RS05210
gene id: 2133959:D1093_RS05210
uniprot id: A0A5B9CX08
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

2133959:D1093 RS07005
gene id: 2133959:D1093_RS07005
uniprot id: A0A5B9CY22
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

2133959:D1093 RS03635
gene id: 2133959:D1093_RS03635
uniprot id: A0A5B9CWC4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

2133959:D1093 RS01885
gene id: 2133959:D1093_RS01885
uniprot id: A0A5B9CVQ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmB/CycW/HelB family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

2133959:D1093 RS03600
gene id: 2133959:D1093_RS03600
uniprot id: A0A5B9CVK1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

2133959:D1093 RS00385
gene id: 2133959:D1093_RS00385
uniprot id: A0A5B9CU22
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

2133959:D1093 RS06505
gene id: 2133959:D1093_RS06505
uniprot id: A0A5B9CY98
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

2133959:D1093 RS01825
gene id: 2133959:D1093_RS01825
uniprot id: A0A5B9CVP0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecB family.
messages: Cytoplasm
messages: Homotetramer, a dimer of dimers. One homotetramer interacts with 1 SecA dimer.
messages: One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.

2133959:D1093 RS00265
gene id: 2133959:D1093_RS00265
uniprot id: A0A5B9CUP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

2133959:D1093 RS05935
gene id: 2133959:D1093_RS05935
uniprot id: A0A5B9CVK1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

2133959:D1093 RS00580
gene id: 2133959:D1093_RS00580
uniprot id: A0A5B9CUR7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

2133959:D1093 RS03645
gene id: 2133959:D1093_RS03645
uniprot id: A0A5B9CW91
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

2133959:D1093 RS01900
gene id: 2133959:D1093_RS01900
uniprot id: A0A5B9CVC6
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

2133959:D1093 RS05880
gene id: 2133959:D1093_RS05880
uniprot id: A0A5B9CYJ2
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

2133959:D1093 RS09335
gene id: 2133959:D1093_RS09335
uniprot id: A0A5B9CZ70
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

2133959:D1093 RS05285
gene id: 2133959:D1093_RS05285
uniprot id: A0A5B9CWI3
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

2133959:D1093 RS05315
gene id: 2133959:D1093_RS05315
uniprot id: A0A5B9CWG2
names: Subcellular Location Annotation
messages: Cytoplasm

2133959:D1093 RS05870
gene id: 2133959:D1093_RS05870
uniprot id: A0A5B9CXE2
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

2133959:D1093 RS00495
gene id: 2133959:D1093_RS00495
uniprot id: A0A5B9CU33
names: Similarity
messages: Belongs to the ABC transporter superfamily.

2133959:D1093 RS08265
gene id: 2133959:D1093_RS08265
uniprot id: A0A5B9CY07
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

2133959:D1093 RS09295
gene id: 2133959:D1093_RS09295
uniprot id: A0A5B9CZY6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

2133959:D1093 RS04645
gene id: 2133959:D1093_RS04645
uniprot id: A0A5B9CW65
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Catalyzes the dehydration of 6-phospho-D-gluconate to 2-dehydro-3-deoxy-6-phospho-D-gluconate.

2133959:D1093 RS07080
gene id: 2133959:D1093_RS07080
uniprot id: A0A5B9CY76
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

2133959:D1093 RS05970
gene id: 2133959:D1093_RS05970
uniprot id: A0A5B9CX88
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

2133959:D1093 RS06990
gene id: 2133959:D1093_RS06990
uniprot id: A0A5B9CXE7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

2133959:D1093 RS06050
gene id: 2133959:D1093_RS06050
uniprot id: A0A5B9CYM2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

2133959:D1093 RS01240
gene id: 2133959:D1093_RS01240
uniprot id: A0A5B9CUH3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BA14k family.
messages: Cell membrane
messages: Has immunoglobulin-binding and hemagglutination properties, and can bind to mannose. Essential for virulence. May be involved in LPS biosynthesis or polysaccharide transport.
messages: Membrane

2133959:D1093 RS06045
gene id: 2133959:D1093_RS06045
uniprot id: A0A5B9CWV2
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2133959:D1093 RS03590
gene id: 2133959:D1093_RS03590
uniprot id: A0A5B9CX62
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

2133959:D1093 RS03660
gene id: 2133959:D1093_RS03660
uniprot id: A0A5B9CWG7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

2133959:D1093 RS06995
gene id: 2133959:D1093_RS06995
uniprot id: A0A5B9CXS2
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2133959:D1093 RS05865
gene id: 2133959:D1093_RS05865
uniprot id: A0A5B9CYB8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

2133959:D1093 RS00725
gene id: 2133959:D1093_RS00725
uniprot id: A0A5B9CU74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone-like protein H-NS family.
messages: nucleoid

2133959:D1093 RS01355
gene id: 2133959:D1093_RS01355
uniprot id: A0A5B9CV00
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2133959:D1093 RS00885
gene id: 2133959:D1093_RS00885
uniprot id: A0A5B9CV59
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur, cytochrome b-556, and a hydrophobic anchor protein.

2133959:D1093 RS07915
gene id: 2133959:D1093_RS07915
uniprot id: A0A5B9CYG7
names: Similarity
messages: Belongs to the virb1 family.

2133959:D1093 RS05010
gene id: 2133959:D1093_RS05010
uniprot id: A0A5B9CX50
names: Similarity
messages: Belongs to the ros/MucR family.

2133959:D1093 RS05955
gene id: 2133959:D1093_RS05955
uniprot id: A0A5B9CXN1
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

2133959:D1093 RS01420
gene id: 2133959:D1093_RS01420
uniprot id: A0A5B9CVW7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

2133959:D1093 RS07160
gene id: 2133959:D1093_RS07160
uniprot id: A0A5B9CYR3
names: Similarity
messages: Belongs to the RelE toxin family.

2133959:D1093 RS06880
gene id: 2133959:D1093_RS06880
uniprot id: A0A5B9CY03
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

2133959:D1093 RS00585
gene id: 2133959:D1093_RS00585
uniprot id: A0A5B9CVE6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has four main subunits: a(1), b(1), b'(1) and c(9-12).
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

2133959:D1093 RS00035
gene id: 2133959:D1093_RS00035
uniprot id: A0A5B9CTW3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

2133959:D1093 RS03690
gene id: 2133959:D1093_RS03690
uniprot id: A0A5B9CX83
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

2133959:D1093 RS05965
gene id: 2133959:D1093_RS05965
uniprot id: A0A5B9CWV3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

2133959:D1093 RS00575
gene id: 2133959:D1093_RS00575
uniprot id: A0A5B9CV06
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

2133959:D1093 RS02490
gene id: 2133959:D1093_RS02490
uniprot id: A0A5B9CWN5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

2133959:D1093 RS05950
gene id: 2133959:D1093_RS05950
uniprot id: A0A5B9CYK2
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

2133959:D1093 RS01950
gene id: 2133959:D1093_RS01950
uniprot id: A0A5B9CVD4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.