2041044:CPZ25 RS00890
gene id: 2041044:CPZ25_RS00890
uniprot id: A0A4P9C3X9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

2041044:CPZ25 RS07745
gene id: 2041044:CPZ25_RS07745
uniprot id: A0A4V1GLW8
names: Similarity
messages: Belongs to the CpsD/CapB family.

2041044:CPZ25 RS06340
gene id: 2041044:CPZ25_RS06340
uniprot id: A0A4P9C6E1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Membrane

2041044:CPZ25 RS18935
gene id: 2041044:CPZ25_RS18935
uniprot id: A0A4P9CCB7
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

2041044:CPZ25 RS01650
gene id: 2041044:CPZ25_RS01650
uniprot id: A0A4P9C3V9
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

2041044:CPZ25 RS20010
gene id: 2041044:CPZ25_RS20010
uniprot id: A0A4P9CCU9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

2041044:CPZ25 RS06760
gene id: 2041044:CPZ25_RS06760
uniprot id: A0A4P9C6K9
names: Similarity
messages: Belongs to the ThiD family.

2041044:CPZ25 RS01810
gene id: 2041044:CPZ25_RS01810
uniprot id: A0A4P9C3Z2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

2041044:CPZ25 RS17570
gene id: 2041044:CPZ25_RS17570
uniprot id: A0A4P9CEC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Glutamate:GABA antiporter (GGA) (TC 2.A.3.7) family.
messages: Membrane

2041044:CPZ25 RS04780
gene id: 2041044:CPZ25_RS04780
uniprot id: A0A2A5TA39
names: Cofactor
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

2041044:CPZ25 RS10440
gene id: 2041044:CPZ25_RS10440
uniprot id: A0A2A5TGZ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

2041044:CPZ25 RS16775
gene id: 2041044:CPZ25_RS16775
uniprot id: A0A4P9CBA4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

2041044:CPZ25 RS15655
gene id: 2041044:CPZ25_RS15655
uniprot id: A0A4P9CDB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VirD4/TraG family.
messages: Membrane

2041044:CPZ25 RS18285
gene id: 2041044:CPZ25_RS18285
uniprot id: A0A4P9CE08
names: Similarity
messages: Belongs to the PRORSD1 family.

2041044:CPZ25 RS13135
gene id: 2041044:CPZ25_RS13135
uniprot id: A0A4P9C9N7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

2041044:CPZ25 RS13220
gene id: 2041044:CPZ25_RS13220
uniprot id: A0A4V1GM71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

2041044:CPZ25 RS13760
gene id: 2041044:CPZ25_RS13760
uniprot id: A0A4P9CBY4
names: Subcellular Location Annotation
messages: Membrane

2041044:CPZ25 RS13840
gene id: 2041044:CPZ25_RS13840
uniprot id: A0A4P9C9W4
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

2041044:CPZ25 RS10220
gene id: 2041044:CPZ25_RS10220
uniprot id: A0A4P9CA65
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

2041044:CPZ25 RS11010
gene id: 2041044:CPZ25_RS11010
uniprot id: A0A2A5TGZ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

2041044:CPZ25 RS06415
gene id: 2041044:CPZ25_RS06415
uniprot id: A0A4P9C8K0
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

2041044:CPZ25 RS08360
gene id: 2041044:CPZ25_RS08360
uniprot id: A0A4V1GLY0
names: Function
names: Similarity
messages: Belongs to the RapZ-like family.
messages: Displays ATPase and GTPase activities.

2041044:CPZ25 RS03340
gene id: 2041044:CPZ25_RS03340
uniprot id: A0A4P9C4W3
names: Similarity
messages: Belongs to the V-ATPase E subunit family.

2041044:CPZ25 RS06160
gene id: 2041044:CPZ25_RS06160
uniprot id: A0A4P9CDB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

2041044:CPZ25 RS05365
gene id: 2041044:CPZ25_RS05365
uniprot id: A0A4P9C5X4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

2041044:CPZ25 RS06305
gene id: 2041044:CPZ25_RS06305
uniprot id: A0A4P9C6E9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CbiN family.
messages: Cell membrane
messages: Forms an energy-coupling factor (ECF) transporter complex composed of an ATP-binding protein (A component, CbiO), a transmembrane protein (T component, CbiQ) and 2 possible substrate-capture proteins (S components, CbiM and CbiN) of unknown stoichimetry.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import.

2041044:CPZ25 RS17040
gene id: 2041044:CPZ25_RS17040
uniprot id: A0A4P9CDH4
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

2041044:CPZ25 RS03865
gene id: 2041044:CPZ25_RS03865
uniprot id: A0A4P9C552
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

2041044:CPZ25 RS16570
gene id: 2041044:CPZ25_RS16570
uniprot id: A0A4P9CDD1
names: Function
names: Similarity
messages: Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).

2041044:CPZ25 RS08845
gene id: 2041044:CPZ25_RS08845
uniprot id: A0A4V1GLY9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

2041044:CPZ25 RS13755
gene id: 2041044:CPZ25_RS13755
uniprot id: A0A4P9C9U6
names: Similarity
messages: Belongs to the trimethylamine methyltransferase family.

2041044:CPZ25 RS15085
gene id: 2041044:CPZ25_RS15085
uniprot id: A0A4P9CAI7
names: Similarity
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

2041044:CPZ25 RS04730
gene id: 2041044:CPZ25_RS04730
uniprot id: A0A2A5TG69
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by GTP. Inhibited by UTP.
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2041044:CPZ25 RS11035
gene id: 2041044:CPZ25_RS11035
uniprot id: A0A4P9C8M9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

2041044:CPZ25 RS10835
gene id: 2041044:CPZ25_RS10835
uniprot id: A0A4P9C8C4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.

2041044:CPZ25 RS02900
gene id: 2041044:CPZ25_RS02900
uniprot id: A0A4P9C4Q8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

2041044:CPZ25 RS16675
gene id: 2041044:CPZ25_RS16675
uniprot id: A0A4P9CDF0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen.
messages: Homooctamer.

2041044:CPZ25 RS02825
gene id: 2041044:CPZ25_RS02825
uniprot id: A0A4P9C6T2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell membrane
messages: Probably interacts with PlsX.

2041044:CPZ25 RS04160
gene id: 2041044:CPZ25_RS04160
uniprot id: A0A4P9C7G9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

2041044:CPZ25 RS10165
gene id: 2041044:CPZ25_RS10165
uniprot id: A0A4P9C874
names: Subcellular Location Annotation
messages: Membrane

2041044:CPZ25 RS10420
gene id: 2041044:CPZ25_RS10420
uniprot id: A0A4P9C888
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

2041044:CPZ25 RS08140
gene id: 2041044:CPZ25_RS08140
uniprot id: A0A4P9C968
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

2041044:CPZ25 RS16320
gene id: 2041044:CPZ25_RS16320
uniprot id: A0A4P9CDR9
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

2041044:CPZ25 RS11015
gene id: 2041044:CPZ25_RS11015
uniprot id: A0A4P9C8N5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

2041044:CPZ25 RS07285
gene id: 2041044:CPZ25_RS07285
uniprot id: A0A4P9C6U2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidylate synthase ThyX family.
messages: Binds 4 FAD per tetramer. Each FAD binding site is formed by three monomers.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
messages: Homotetramer.

2041044:CPZ25 RS13260
gene id: 2041044:CPZ25_RS13260
uniprot id: A0A4P9CA11
names: Similarity
messages: Belongs to the IlvD/Edd family.

2041044:CPZ25 RS14030
gene id: 2041044:CPZ25_RS14030
uniprot id: A0A4P9CA57
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

2041044:CPZ25 RS06600
gene id: 2041044:CPZ25_RS06600
uniprot id: A0A4P9C6B0
names: Similarity
messages: Belongs to the asp23 family.

2041044:CPZ25 RS03485
gene id: 2041044:CPZ25_RS03485
uniprot id: A0A4P9C512
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

2041044:CPZ25 RS02915
gene id: 2041044:CPZ25_RS02915
uniprot id: A0A4P9CCX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

2041044:CPZ25 RS14065
gene id: 2041044:CPZ25_RS14065
uniprot id: A0A2A5TIU4
names: Similarity
messages: Belongs to the trimethylamine methyltransferase family.

2041044:CPZ25 RS10660
gene id: 2041044:CPZ25_RS10660
uniprot id: A0A4P9C8H2
names: Function
names: Similarity
messages: Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor.
messages: Belongs to the biotin--protein ligase family.

2041044:CPZ25 RS06605
gene id: 2041044:CPZ25_RS06605
uniprot id: A0A4P9C6C1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

2041044:CPZ25 RS02870
gene id: 2041044:CPZ25_RS02870
uniprot id: A0A4P9C4V6
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

2041044:CPZ25 RS16660
gene id: 2041044:CPZ25_RS16660
uniprot id: A0A4P9CB98
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

2041044:CPZ25 RS10320
gene id: 2041044:CPZ25_RS10320
uniprot id: A0A4P9C870
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

2041044:CPZ25 RS13080
gene id: 2041044:CPZ25_RS13080
uniprot id: A0A4P9C9D9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

2041044:CPZ25 RS14450
gene id: 2041044:CPZ25_RS14450
uniprot id: A0A4P9CA69
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

2041044:CPZ25 RS01385
gene id: 2041044:CPZ25_RS01385
uniprot id: A0A4P9C3R3
names: Subcellular Location Annotation
messages: Membrane

2041044:CPZ25 RS15220
gene id: 2041044:CPZ25_RS15220
uniprot id: A0A4P9CAY8
names: Similarity
messages: Belongs to the asp23 family.

2041044:CPZ25 RS18900
gene id: 2041044:CPZ25_RS18900
uniprot id: A0A4P9CCC0
names: Subcellular Location Annotation
messages: Membrane

2041044:CPZ25 RS10260
gene id: 2041044:CPZ25_RS10260
uniprot id: A0A4P9C861
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex.
messages: Belongs to the ABC transporter superfamily. Energy-coupling factor EcfA family.
messages: Cell membrane
messages: Forms a stable energy-coupling factor (ECF) transporter complex composed of 2 membrane-embedded substrate-binding proteins (S component), 2 ATP-binding proteins (A component) and 2 transmembrane proteins (T component).
messages: Membrane

2041044:CPZ25 RS16605
gene id: 2041044:CPZ25_RS16605
uniprot id: A0A4P9CB86
names: Similarity
messages: Belongs to the CobH/CbiC family.

2041044:CPZ25 RS13360
gene id: 2041044:CPZ25_RS13360
uniprot id: A0A4P9CA31
names: Similarity
messages: Belongs to the FGGY kinase family.

2041044:CPZ25 RS01610
gene id: 2041044:CPZ25_RS01610
uniprot id: A0A4P9C5X7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

2041044:CPZ25 RS02955
gene id: 2041044:CPZ25_RS02955
uniprot id: A0A4P9C4J9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

2041044:CPZ25 RS06550
gene id: 2041044:CPZ25_RS06550
uniprot id: A0A4P9CD70
names: Similarity
messages: Belongs to the EamA transporter family.

2041044:CPZ25 RS07250
gene id: 2041044:CPZ25_RS07250
uniprot id: A0A4P9C6U7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LuxS family.
messages: Homodimer.
messages: Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).

2041044:CPZ25 RS19190
gene id: 2041044:CPZ25_RS19190
uniprot id: A0A4P9CCD3
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

2041044:CPZ25 RS12740
gene id: 2041044:CPZ25_RS12740
uniprot id: A0A4P9CBQ0
names: Similarity
messages: Belongs to the UPF0047 family.

2041044:CPZ25 RS15805
gene id: 2041044:CPZ25_RS15805
uniprot id: A0A4P9CAX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acyl-ACP thioesterase family.
messages: chloroplast

2041044:CPZ25 RS19110
gene id: 2041044:CPZ25_RS19110
uniprot id: A0A4P9CCF5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

2041044:CPZ25 RS19640
gene id: 2041044:CPZ25_RS19640
uniprot id: A0A4P9CCP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VirD4/TraG family.
messages: Membrane

2041044:CPZ25 RS03355
gene id: 2041044:CPZ25_RS03355
uniprot id: A0A4P9CF48
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit.

2041044:CPZ25 RS12760
gene id: 2041044:CPZ25_RS12760
uniprot id: A0A4V1GM62
names: Similarity
messages: Belongs to the SorC transcriptional regulatory family.

2041044:CPZ25 RS07845
gene id: 2041044:CPZ25_RS07845
uniprot id: A0A4P9C982
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

2041044:CPZ25 RS19045
gene id: 2041044:CPZ25_RS19045
uniprot id: A0A4P9CEJ2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2041044:CPZ25 RS00255
gene id: 2041044:CPZ25_RS00255
uniprot id: A0A4P9C3D2
names: Similarity
messages: Belongs to the TelA family.

2041044:CPZ25 RS17850
gene id: 2041044:CPZ25_RS17850
uniprot id: A0A4P9CEG8
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

2041044:CPZ25 RS14185
gene id: 2041044:CPZ25_RS14185
uniprot id: A0A4P9CCH6
names: Similarity
messages: Belongs to the FBPase class 3 family.

2041044:CPZ25 RS13635
gene id: 2041044:CPZ25_RS13635
uniprot id: A0A4V1GM79
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

2041044:CPZ25 RS13025
gene id: 2041044:CPZ25_RS13025
uniprot id: A0A4P9C9I0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GdpP/PdeA phosphodiesterase family.
messages: Cell membrane
messages: For phosphodiesterase activity, probably binds 2 Mn(2+) per subunit.
messages: Has phosphodiesterase (PDE) activity against cyclic-di-AMP (c-di-AMP).

2041044:CPZ25 RS07855
gene id: 2041044:CPZ25_RS07855
uniprot id: A0A4P9C740
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

2041044:CPZ25 RS15075
gene id: 2041044:CPZ25_RS15075
uniprot id: A0A4V1GMA6
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

2041044:CPZ25 RS03305
gene id: 2041044:CPZ25_RS03305
uniprot id: A0A4P9C4X8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

2041044:CPZ25 RS13245
gene id: 2041044:CPZ25_RS13245
uniprot id: A0A4P9C9J9
names: Similarity
messages: Belongs to the trimethylamine methyltransferase family.

2041044:CPZ25 RS10715
gene id: 2041044:CPZ25_RS10715
uniprot id: A0A4P9CAG8
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2041044:CPZ25 RS18655
gene id: 2041044:CPZ25_RS18655
uniprot id: A0A4P9CED3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

2041044:CPZ25 RS13540
gene id: 2041044:CPZ25_RS13540
uniprot id: A0A4P9C9R2
names: Similarity
messages: Belongs to the RutC family.

2041044:CPZ25 RS10275
gene id: 2041044:CPZ25_RS10275
uniprot id: A0A4P9CA72
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

2041044:CPZ25 RS18355
gene id: 2041044:CPZ25_RS18355
uniprot id: A0A4P9CC09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

2041044:CPZ25 RS17305
gene id: 2041044:CPZ25_RS17305
uniprot id: A0A4P9CBL7
names: Similarity
messages: Belongs to the glutathione peroxidase family.

2041044:CPZ25 RS04915
gene id: 2041044:CPZ25_RS04915
uniprot id: A0A2A5TG05
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

2041044:CPZ25 RS15825
gene id: 2041044:CPZ25_RS15825
uniprot id: A0A4P9CB83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell membrane
messages: Membrane

2041044:CPZ25 RS01165
gene id: 2041044:CPZ25_RS01165
uniprot id: A0A4P9CD88
names: Similarity
messages: Belongs to the four-carbon acid sugar kinase family.

2041044:CPZ25 RS03310
gene id: 2041044:CPZ25_RS03310
uniprot id: A0A4P9C6S4
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

2041044:CPZ25 RS19870
gene id: 2041044:CPZ25_RS19870
uniprot id: A0A4P9CEZ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

2041044:CPZ25 RS16985
gene id: 2041044:CPZ25_RS16985
uniprot id: A0A4P9CBH7
names: Similarity
messages: Belongs to the phosphate acetyltransferase and butyryltransferase family.

2041044:CPZ25 RS03345
gene id: 2041044:CPZ25_RS03345
uniprot id: A0A4P9C4P4
names: Similarity
messages: Belongs to the V-ATPase V0D/AC39 subunit family.

2041044:CPZ25 RS07750
gene id: 2041044:CPZ25_RS07750
uniprot id: A0A4P9C725
names: Subcellular Location Annotation
messages: Membrane

2041044:CPZ25 RS04850
gene id: 2041044:CPZ25_RS04850
uniprot id: A0A2A5TA09
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

2041044:CPZ25 RS09790
gene id: 2041044:CPZ25_RS09790
uniprot id: A0A4P9C7V0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

2041044:CPZ25 RS16280
gene id: 2041044:CPZ25_RS16280
uniprot id: A0A4P9CB62
names: Similarity
messages: Belongs to the SorC transcriptional regulatory family.

2041044:CPZ25 RS01300
gene id: 2041044:CPZ25_RS01300
uniprot id: A0A4P9C5S3
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

2041044:CPZ25 RS02190
gene id: 2041044:CPZ25_RS02190
uniprot id: A0A4P9C4F2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

2041044:CPZ25 RS17910
gene id: 2041044:CPZ25_RS17910
uniprot id: A0A4P9CBW3
names: Similarity
messages: Belongs to the EamA transporter family.

2041044:CPZ25 RS16380
gene id: 2041044:CPZ25_RS16380
uniprot id: A0A4P9CB78
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

2041044:CPZ25 RS08875
gene id: 2041044:CPZ25_RS08875
uniprot id: A0A4P9C9H6
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

2041044:CPZ25 RS19120
gene id: 2041044:CPZ25_RS19120
uniprot id: A0A4V1GMI1
names: Similarity
messages: Belongs to the asp23 family.

2041044:CPZ25 RS13630
gene id: 2041044:CPZ25_RS13630
uniprot id: A0A4P9CBX8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

2041044:CPZ25 RS13990
gene id: 2041044:CPZ25_RS13990
uniprot id: A0A4V1GM86
names: Similarity
messages: Belongs to the SorC transcriptional regulatory family.

2041044:CPZ25 RS14255
gene id: 2041044:CPZ25_RS14255
uniprot id: A0A4P9CC87
names: Similarity
messages: Belongs to the trimethylamine methyltransferase family.

2041044:CPZ25 RS19330
gene id: 2041044:CPZ25_RS19330
uniprot id: A0A4P9CCN9
names: Subcellular Location Annotation
messages: Membrane

2041044:CPZ25 RS02545
gene id: 2041044:CPZ25_RS02545
uniprot id: A0A4P9C4Q5
names: Subcellular Location Annotation
messages: Cytoplasm

2041044:CPZ25 RS18510
gene id: 2041044:CPZ25_RS18510
uniprot id: A0A4P9CC54
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

2041044:CPZ25 RS02665
gene id: 2041044:CPZ25_RS02665
uniprot id: A0A4P9C4K1
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

2041044:CPZ25 RS01135
gene id: 2041044:CPZ25_RS01135
uniprot id: A0A4P9C3X2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

2041044:CPZ25 RS11835
gene id: 2041044:CPZ25_RS11835
uniprot id: A0A4P9CB19
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2041044:CPZ25 RS19530
gene id: 2041044:CPZ25_RS19530
uniprot id: A0A4P9CCW9
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

2041044:CPZ25 RS12870
gene id: 2041044:CPZ25_RS12870
uniprot id: A0A4V1GM64
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

2041044:CPZ25 RS14915
gene id: 2041044:CPZ25_RS14915
uniprot id: A0A2A5TIU4
names: Similarity
messages: Belongs to the trimethylamine methyltransferase family.

2041044:CPZ25 RS09960
gene id: 2041044:CPZ25_RS09960
uniprot id: A0A4P9CA18
names: Similarity
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.

2041044:CPZ25 RS14490
gene id: 2041044:CPZ25_RS14490
uniprot id: A0A4V1GM95
names: Subcellular Location Annotation
messages: Membrane

2041044:CPZ25 RS03295
gene id: 2041044:CPZ25_RS03295
uniprot id: A0A4P9C4N4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

2041044:CPZ25 RS01670
gene id: 2041044:CPZ25_RS01670
uniprot id: A0A4P9C664
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LPG synthase family.
messages: Catalyzes the transfer of a lysyl group from L-lysyl-tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms.
messages: Cell membrane
messages: Membrane

2041044:CPZ25 RS04865
gene id: 2041044:CPZ25_RS04865
uniprot id: A0A2A5TG16
names: Similarity
messages: Belongs to the UPF0749 family.

2041044:CPZ25 RS19585
gene id: 2041044:CPZ25_RS19585
uniprot id: A0A4P9CCP1
names: Similarity
messages: Belongs to the type IA topoisomerase family.

2041044:CPZ25 RS06310
gene id: 2041044:CPZ25_RS06310
uniprot id: A0A4P9C6M1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CbiM family.
messages: Cell membrane
messages: Forms an energy-coupling factor (ECF) transporter complex composed of an ATP-binding protein (A component, CbiO), a transmembrane protein (T component, CbiQ) and 2 possible substrate-capture proteins (S components, CbiM and CbiN) of unknown stoichimetry.
messages: Membrane
messages: Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import.

2041044:CPZ25 RS09915
gene id: 2041044:CPZ25_RS09915
uniprot id: A0A4P9C854
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CbiN family.
messages: Cell membrane
messages: Forms an energy-coupling factor (ECF) transporter complex composed of an ATP-binding protein (A component, CbiO), a transmembrane protein (T component, CbiQ) and 2 possible substrate-capture proteins (S components, CbiM and CbiN) of unknown stoichimetry.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import.

2041044:CPZ25 RS13565
gene id: 2041044:CPZ25_RS13565
uniprot id: A0A4P9CA64
names: Subcellular Location Annotation
messages: Membrane

2041044:CPZ25 RS12100
gene id: 2041044:CPZ25_RS12100
uniprot id: A0A4P9C941
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

2041044:CPZ25 RS08840
gene id: 2041044:CPZ25_RS08840
uniprot id: A0A4P9C9M3
names: Similarity
messages: Belongs to the UPF0342 family.

2041044:CPZ25 RS09580
gene id: 2041044:CPZ25_RS09580
uniprot id: A0A2A5T8F5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

2041044:CPZ25 RS04740
gene id: 2041044:CPZ25_RS04740
uniprot id: A0A2A5TA19
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

2041044:CPZ25 RS02055
gene id: 2041044:CPZ25_RS02055
uniprot id: A0A4V1GLK9
names: Subcellular Location Annotation
messages: Membrane

2041044:CPZ25 RS04610
gene id: 2041044:CPZ25_RS04610
uniprot id: A0A2A5TA80
names: Similarity
messages: Belongs to the trimethylamine methyltransferase family.

2041044:CPZ25 RS16645
gene id: 2041044:CPZ25_RS16645
uniprot id: A0A4P9CD99
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

2041044:CPZ25 RS09075
gene id: 2041044:CPZ25_RS09075
uniprot id: A0A4P9C7P7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

2041044:CPZ25 RS08195
gene id: 2041044:CPZ25_RS08195
uniprot id: A0A4P9C9H1
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

2041044:CPZ25 RS20020
gene id: 2041044:CPZ25_RS20020
uniprot id: A0A4V1GMJ7
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

2041044:CPZ25 RS03315
gene id: 2041044:CPZ25_RS03315
uniprot id: A0A4P9C716
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

2041044:CPZ25 RS01710
gene id: 2041044:CPZ25_RS01710
uniprot id: A0A4P9C469
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

2041044:CPZ25 RS17450
gene id: 2041044:CPZ25_RS17450
uniprot id: A0A4P9CBQ1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

2041044:CPZ25 RS14685
gene id: 2041044:CPZ25_RS14685
uniprot id: A0A4P9CCF7
names: Similarity
messages: Belongs to the GSP E family.

2041044:CPZ25 RS06710
gene id: 2041044:CPZ25_RS06710
uniprot id: A0A4P9C6C7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SepF family.
messages: Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
messages: Cytoplasm
messages: Homodimer. Interacts with FtsZ.

2041044:CPZ25 RS08595
gene id: 2041044:CPZ25_RS08595
uniprot id: A0A4P9C7A7
names: Subcellular Location Annotation
messages: Membrane

2041044:CPZ25 RS11730
gene id: 2041044:CPZ25_RS11730
uniprot id: A0A4P9CAZ5
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

2041044:CPZ25 RS18920
gene id: 2041044:CPZ25_RS18920
uniprot id: A0A4P9CDD2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

2041044:CPZ25 RS07780
gene id: 2041044:CPZ25_RS07780
uniprot id: A0A4P9C9B7
names: Activity Regulation
names: Function
names: Similarity
names: Subunit
messages: Activated by phosphorylation and inhibited by fructose 1,6-bisphosphate (FBP).
messages: Belongs to the FGGY kinase family.
messages: Homotetramer and homodimer (in equilibrium).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.

2041044:CPZ25 RS13300
gene id: 2041044:CPZ25_RS13300
uniprot id: A0A4P9CBP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0394 family.
messages: Membrane

2041044:CPZ25 RS03780
gene id: 2041044:CPZ25_RS03780
uniprot id: A0A4P9C558
names: Similarity
messages: Belongs to the pirin family.

2041044:CPZ25 RS16725
gene id: 2041044:CPZ25_RS16725
uniprot id: A0A4P9CDG1
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

2041044:CPZ25 RS06520
gene id: 2041044:CPZ25_RS06520
uniprot id: A0A4P9C6Q2
names: Function
names: Similarity
messages: Belongs to the flavodoxin family.
messages: Low-potential electron donor to a number of redox enzymes.

2041044:CPZ25 RS06295
gene id: 2041044:CPZ25_RS06295
uniprot id: A0A4P9C873
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane
messages: Part of an ABC transporter complex. Responsible for energy coupling to the transport system.

2041044:CPZ25 RS01105
gene id: 2041044:CPZ25_RS01105
uniprot id: A0A4P9C413
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpC family.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

2041044:CPZ25 RS10280
gene id: 2041044:CPZ25_RS10280
uniprot id: A0A4P9CAH6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

2041044:CPZ25 RS02495
gene id: 2041044:CPZ25_RS02495
uniprot id: A0A4P9C4P6
names: Similarity
messages: Belongs to the type IA topoisomerase family.

2041044:CPZ25 RS19855
gene id: 2041044:CPZ25_RS19855
uniprot id: A0A4P9CFF2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

2041044:CPZ25 RS04725
gene id: 2041044:CPZ25_RS04725
uniprot id: A0A2A5TA57
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

2041044:CPZ25 RS14120
gene id: 2041044:CPZ25_RS14120
uniprot id: A0A4P9CA56
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

2041044:CPZ25 RS10240
gene id: 2041044:CPZ25_RS10240
uniprot id: A0A4P9CA95
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

2041044:CPZ25 RS03365
gene id: 2041044:CPZ25_RS03365
uniprot id: A0A4P9C6T3
names: Function
names: Similarity
messages: Belongs to the V-ATPase D subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

2041044:CPZ25 RS16690
gene id: 2041044:CPZ25_RS16690
uniprot id: A0A4P9CBD3
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

2041044:CPZ25 RS04470
gene id: 2041044:CPZ25_RS04470
uniprot id: A0A2A5TGI7
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

2041044:CPZ25 RS02860
gene id: 2041044:CPZ25_RS02860
uniprot id: A0A4P9C6T0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

2041044:CPZ25 RS00570
gene id: 2041044:CPZ25_RS00570
uniprot id: A0A4P9C3M1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily.
messages: Cell membrane

2041044:CPZ25 RS09785
gene id: 2041044:CPZ25_RS09785
uniprot id: A0A4P9C817
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

2041044:CPZ25 RS09770
gene id: 2041044:CPZ25_RS09770
uniprot id: A0A4P9C887
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

2041044:CPZ25 RS01075
gene id: 2041044:CPZ25_RS01075
uniprot id: A0A4P9C3L0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

2041044:CPZ25 RS00445
gene id: 2041044:CPZ25_RS00445
uniprot id: A0A4P9C3Q0
names: Similarity
messages: Belongs to the EamA transporter family.

2041044:CPZ25 RS10815
gene id: 2041044:CPZ25_RS10815
uniprot id: A0A4P9C8Q9
names: Similarity
messages: Belongs to the phosphohexose mutase family.

2041044:CPZ25 RS02885
gene id: 2041044:CPZ25_RS02885
uniprot id: A0A4P9C4N3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane
messages: This protein catalyzes the committed step to the synthesis of the acidic phospholipids.

2041044:CPZ25 RS10830
gene id: 2041044:CPZ25_RS10830
uniprot id: A0A4P9C8J3
names: Similarity
messages: Belongs to the LacAB/RpiB family.

2041044:CPZ25 RS07670
gene id: 2041044:CPZ25_RS07670
uniprot id: A0A4P9C8X6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

2041044:CPZ25 RS03805
gene id: 2041044:CPZ25_RS03805
uniprot id: A0A4P9C7A6
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

2041044:CPZ25 RS08005
gene id: 2041044:CPZ25_RS08005
uniprot id: A0A4V1GLX3
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

2041044:CPZ25 RS14160
gene id: 2041044:CPZ25_RS14160
uniprot id: A0A4P9CA12
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

2041044:CPZ25 RS14025
gene id: 2041044:CPZ25_RS14025
uniprot id: A0A4P9CAD9
names: Function
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The phosphoryl group from phosphoenolpyruvate (PEP) is transferred to the phosphoryl carrier protein HPr by enzyme I. Phospho-HPr then transfers it to the PTS EIIA domain.

2041044:CPZ25 RS19695
gene id: 2041044:CPZ25_RS19695
uniprot id: A0A4V1GMJ2
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

2041044:CPZ25 RS13170
gene id: 2041044:CPZ25_RS13170
uniprot id: A0A4V1GM70
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

2041044:CPZ25 RS04840
gene id: 2041044:CPZ25_RS04840
uniprot id: A0A2A5TG54
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

2041044:CPZ25 RS06650
gene id: 2041044:CPZ25_RS06650
uniprot id: A0A4P9C6J2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

2041044:CPZ25 RS16975
gene id: 2041044:CPZ25_RS16975
uniprot id: A0A4P9CE37
names: Subcellular Location Annotation
messages: Membrane

2041044:CPZ25 RS15080
gene id: 2041044:CPZ25_RS15080
uniprot id: A0A4P9CAJ7
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

2041044:CPZ25 RS10300
gene id: 2041044:CPZ25_RS10300
uniprot id: A0A4V1GM16
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

2041044:CPZ25 RS06225
gene id: 2041044:CPZ25_RS06225
uniprot id: A0A4P9C649
names: Subcellular Location Annotation
messages: Membrane

2041044:CPZ25 RS13065
gene id: 2041044:CPZ25_RS13065
uniprot id: A0A4P9CBM4
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2041044:CPZ25 RS05885
gene id: 2041044:CPZ25_RS05885
uniprot id: A0A2A5T8D7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

2041044:CPZ25 RS00500
gene id: 2041044:CPZ25_RS00500
uniprot id: A0A4V1GLH9
names: Similarity
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.

2041044:CPZ25 RS20055
gene id: 2041044:CPZ25_RS20055
uniprot id: A0A4P9CFH9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

2041044:CPZ25 RS18950
gene id: 2041044:CPZ25_RS18950
uniprot id: A0A4P9CF03
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

2041044:CPZ25 RS18830
gene id: 2041044:CPZ25_RS18830
uniprot id: A0A4P9CEF6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

2041044:CPZ25 RS17460
gene id: 2041044:CPZ25_RS17460
uniprot id: A0A4P9CDN8
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

2041044:CPZ25 RS01150
gene id: 2041044:CPZ25_RS01150
uniprot id: A0A4P9C3W8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

2041044:CPZ25 RS02015
gene id: 2041044:CPZ25_RS02015
uniprot id: A0A4P9C438
names: Similarity
messages: Belongs to the AOR/FOR family.

2041044:CPZ25 RS15315
gene id: 2041044:CPZ25_RS15315
uniprot id: A0A4P9CCQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

2041044:CPZ25 RS10975
gene id: 2041044:CPZ25_RS10975
uniprot id: A0A4V1GM29
names: Function
names: Similarity
messages: Belongs to the PyrI family.
messages: Involved in allosteric regulation of aspartate carbamoyltransferase.

2041044:CPZ25 RS10285
gene id: 2041044:CPZ25_RS10285
uniprot id: A0A4P9C8B0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

2041044:CPZ25 RS00945
gene id: 2041044:CPZ25_RS00945
uniprot id: A0A4P9C5U6
names: Similarity
messages: In the N-terminal section; belongs to the zinc metallo-hydrolase group 3 family.

2041044:CPZ25 RS15090
gene id: 2041044:CPZ25_RS15090
uniprot id: A0A4P9CAK9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

2041044:CPZ25 RS11925
gene id: 2041044:CPZ25_RS11925
uniprot id: A0A4P9C999
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

2041044:CPZ25 RS17215
gene id: 2041044:CPZ25_RS17215
uniprot id: A0A4P9CBH8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

2041044:CPZ25 RS11350
gene id: 2041044:CPZ25_RS11350
uniprot id: A0A4P9C8Q1
names: Similarity
messages: Belongs to the HepT RNase toxin family.

2041044:CPZ25 RS10090
gene id: 2041044:CPZ25_RS10090
uniprot id: A0A4P9C867
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane

2041044:CPZ25 RS15200
gene id: 2041044:CPZ25_RS15200
uniprot id: A0A4P9CAK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

2041044:CPZ25 RS04925
gene id: 2041044:CPZ25_RS04925
uniprot id: A0A2A5TA75
names: Similarity
messages: Belongs to the UPF0237 family.

2041044:CPZ25 RS18370
gene id: 2041044:CPZ25_RS18370
uniprot id: A0A4P9CE77
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

2041044:CPZ25 RS13775
gene id: 2041044:CPZ25_RS13775
uniprot id: A0A4P9CA16
names: Subcellular Location Annotation
messages: Membrane

2041044:CPZ25 RS05385
gene id: 2041044:CPZ25_RS05385
uniprot id: A0A4P9C7T1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

2041044:CPZ25 RS16710
gene id: 2041044:CPZ25_RS16710
uniprot id: A0A4P9CBA5
names: Function
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.

2041044:CPZ25 RS08645
gene id: 2041044:CPZ25_RS08645
uniprot id: A0A4P9C7B6
names: Subcellular Location Annotation
messages: Periplasm

2041044:CPZ25 RS09155
gene id: 2041044:CPZ25_RS09155
uniprot id: A0A4P9C7J1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

2041044:CPZ25 RS10195
gene id: 2041044:CPZ25_RS10195
uniprot id: A0A4V1GM14
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

2041044:CPZ25 RS11805
gene id: 2041044:CPZ25_RS11805
uniprot id: A0A4P9C8X4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M15D family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide.

2041044:CPZ25 RS11875
gene id: 2041044:CPZ25_RS11875
uniprot id: A0A4P9C992
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

2041044:CPZ25 RS11255
gene id: 2041044:CPZ25_RS11255
uniprot id: A0A4P9C8Q7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

2041044:CPZ25 RS18075
gene id: 2041044:CPZ25_RS18075
uniprot id: A0A4V1GMG1
names: Similarity
messages: Belongs to the glycosyltransferase 28 family.

2041044:CPZ25 RS05370
gene id: 2041044:CPZ25_RS05370
uniprot id: A0A4P9C5P1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

2041044:CPZ25 RS10025
gene id: 2041044:CPZ25_RS10025
uniprot id: A0A4P9C8D4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

2041044:CPZ25 RS05980
gene id: 2041044:CPZ25_RS05980
uniprot id: A0A4P9C6G9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 2 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

2041044:CPZ25 RS02835
gene id: 2041044:CPZ25_RS02835
uniprot id: A0A4P9C4M6
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

2041044:CPZ25 RS06385
gene id: 2041044:CPZ25_RS06385
uniprot id: A0A4P9C681
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

2041044:CPZ25 RS13060
gene id: 2041044:CPZ25_RS13060
uniprot id: A0A4P9C9Q1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

2041044:CPZ25 RS14295
gene id: 2041044:CPZ25_RS14295
uniprot id: A0A4P9CCJ8
names: Subcellular Location Annotation
messages: Membrane

2041044:CPZ25 RS16825
gene id: 2041044:CPZ25_RS16825
uniprot id: A0A4P9CBB6
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

2041044:CPZ25 RS11155
gene id: 2041044:CPZ25_RS11155
uniprot id: A0A4P9CAZ1
names: Similarity
messages: Belongs to the EamA transporter family.

2041044:CPZ25 RS02025
gene id: 2041044:CPZ25_RS02025
uniprot id: A0A4P9C647
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

2041044:CPZ25 RS10390
gene id: 2041044:CPZ25_RS10390
uniprot id: A0A4P9C8C9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

2041044:CPZ25 RS17435
gene id: 2041044:CPZ25_RS17435
uniprot id: A0A4P9CDU6
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

2041044:CPZ25 RS04665
gene id: 2041044:CPZ25_RS04665
uniprot id: A0A2A5TG58
names: Similarity
messages: Belongs to the UPF0047 family.

2041044:CPZ25 RS10950
gene id: 2041044:CPZ25_RS10950
uniprot id: A0A4P9CAI0
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

2041044:CPZ25 RS10645
gene id: 2041044:CPZ25_RS10645
uniprot id: A0A4P9C8G1
names: Similarity
messages: Belongs to the bacterial microcompartments protein family.

2041044:CPZ25 RS03320
gene id: 2041044:CPZ25_RS03320
uniprot id: A0A4P9C4Y5
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

2041044:CPZ25 RS00495
gene id: 2041044:CPZ25_RS00495
uniprot id: A0A4P9C3Q8
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

2041044:CPZ25 RS10310
gene id: 2041044:CPZ25_RS10310
uniprot id: A0A4P9C8A3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

2041044:CPZ25 RS11920
gene id: 2041044:CPZ25_RS11920
uniprot id: A0A4P9CBC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

2041044:CPZ25 RS04000
gene id: 2041044:CPZ25_RS04000
uniprot id: A0A4P9C7E3
names: Similarity
messages: Belongs to the RutC family.

2041044:CPZ25 RS09035
gene id: 2041044:CPZ25_RS09035
uniprot id: A0A4P9C7N5
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

2041044:CPZ25 RS06660
gene id: 2041044:CPZ25_RS06660
uniprot id: A0A4P9C6C9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

2041044:CPZ25 RS10955
gene id: 2041044:CPZ25_RS10955
uniprot id: A0A4P9CAV3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate.
messages: Cytoplasm

2041044:CPZ25 RS08545
gene id: 2041044:CPZ25_RS08545
uniprot id: A0A4P9C799
names: Similarity
messages: Belongs to the carotenoid/retinoid oxidoreductase family.

2041044:CPZ25 RS07400
gene id: 2041044:CPZ25_RS07400
uniprot id: A0A4P9C6X3
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

2041044:CPZ25 RS13295
gene id: 2041044:CPZ25_RS13295
uniprot id: A0A4P9C9L0
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

2041044:CPZ25 RS04745
gene id: 2041044:CPZ25_RS04745
uniprot id: A0A2A5TA28
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

2041044:CPZ25 RS08515
gene id: 2041044:CPZ25_RS08515
uniprot id: A0A4P9C7H3
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

2041044:CPZ25 RS07820
gene id: 2041044:CPZ25_RS07820
uniprot id: A0A4P9C745
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.

2041044:CPZ25 RS14420
gene id: 2041044:CPZ25_RS14420
uniprot id: A0A4P9CAJ9
names: Similarity
messages: Belongs to the LacAB/RpiB family.

2041044:CPZ25 RS05995
gene id: 2041044:CPZ25_RS05995
uniprot id: A0A4P9C686
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2041044:CPZ25 RS19185
gene id: 2041044:CPZ25_RS19185
uniprot id: A0A4P9CCF9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

2041044:CPZ25 RS07695
gene id: 2041044:CPZ25_RS07695
uniprot id: A0A4V1GLW7
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

2041044:CPZ25 RS17525
gene id: 2041044:CPZ25_RS17525
uniprot id: A0A4P9CC00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

2041044:CPZ25 RS07215
gene id: 2041044:CPZ25_RS07215
uniprot id: A0A4P9C6U5
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

2041044:CPZ25 RS03235
gene id: 2041044:CPZ25_RS03235
uniprot id: A0A4V1GLN2
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

2041044:CPZ25 RS07730
gene id: 2041044:CPZ25_RS07730
uniprot id: A0A4P9C742
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

2041044:CPZ25 RS15495
gene id: 2041044:CPZ25_RS15495
uniprot id: A0A4P9CCT6
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

2041044:CPZ25 RS10045
gene id: 2041044:CPZ25_RS10045
uniprot id: A0A4P9C7Z2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FNT transporter (TC 2.A.44) family.
messages: Membrane

2041044:CPZ25 RS13055
gene id: 2041044:CPZ25_RS13055
uniprot id: A0A4P9C9Y2
names: Similarity
messages: Belongs to the acylphosphatase family.

2041044:CPZ25 RS04720
gene id: 2041044:CPZ25_RS04720
uniprot id: A0A2A5T9Y0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

2041044:CPZ25 RS01415
gene id: 2041044:CPZ25_RS01415
uniprot id: A0A4P9C473
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

2041044:CPZ25 RS00825
gene id: 2041044:CPZ25_RS00825
uniprot id: A0A4P9C5J3
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

2041044:CPZ25 RS11725
gene id: 2041044:CPZ25_RS11725
uniprot id: A0A4P9C954
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

2041044:CPZ25 RS14740
gene id: 2041044:CPZ25_RS14740
uniprot id: A0A4P9CAQ6
names: Similarity
messages: Belongs to the site-specific recombinase resolvase family.

2041044:CPZ25 RS02920
gene id: 2041044:CPZ25_RS02920
uniprot id: A0A4P9C4R4
names: Similarity
messages: Belongs to the band 7/mec-2 family. Flotillin subfamily.

2041044:CPZ25 RS03405
gene id: 2041044:CPZ25_RS03405
uniprot id: A0A4P9C4Q2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MurCDEF family. MurT subfamily.
messages: Forms a heterodimer with GatD.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The MurT subunit catalyzes the ATP-dependent amidation of D-glutamate residue of lipid II, converting it to an isoglutamine residue.

2041044:CPZ25 RS12030
gene id: 2041044:CPZ25_RS12030
uniprot id: A0A4P9C9B8
names: Subcellular Location Annotation
messages: Bacterial microcompartment

2041044:CPZ25 RS06325
gene id: 2041044:CPZ25_RS06325
uniprot id: A0A4P9C6D6
names: Similarity
messages: Belongs to the glyoxalase I family.

2041044:CPZ25 RS18955
gene id: 2041044:CPZ25_RS18955
uniprot id: A0A4P9CCM1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

2041044:CPZ25 RS04890
gene id: 2041044:CPZ25_RS04890
uniprot id: A0A2A5TG47
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

2041044:CPZ25 RS07715
gene id: 2041044:CPZ25_RS07715
uniprot id: A0A4P9C721
names: Similarity
messages: Belongs to the pyruvate kinase family.
messages: In the C-terminal section; belongs to the PEP-utilizing enzyme family.

2041044:CPZ25 RS10350
gene id: 2041044:CPZ25_RS10350
uniprot id: A0A4P9CAB1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

2041044:CPZ25 RS10425
gene id: 2041044:CPZ25_RS10425
uniprot id: A0A4P9C8C3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

2041044:CPZ25 RS17565
gene id: 2041044:CPZ25_RS17565
uniprot id: A0A4P9CDW7
names: Similarity
messages: Belongs to the group II decarboxylase family.

2041044:CPZ25 RS12550
gene id: 2041044:CPZ25_RS12550
uniprot id: A0A4P9CBC8
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

2041044:CPZ25 RS10445
gene id: 2041044:CPZ25_RS10445
uniprot id: A0A4P9C8K3
names: Subcellular Location Annotation
messages: Cytoplasm

2041044:CPZ25 RS17510
gene id: 2041044:CPZ25_RS17510
uniprot id: A0A4P9CBM0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2041044:CPZ25 RS18270
gene id: 2041044:CPZ25_RS18270
uniprot id: A0A4P9CEP3
names: Subcellular Location Annotation
messages: Membrane

2041044:CPZ25 RS00415
gene id: 2041044:CPZ25_RS00415
uniprot id: A0A4P9C396
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0014 family.
messages: Membrane

2041044:CPZ25 RS03760
gene id: 2041044:CPZ25_RS03760
uniprot id: A0A4P9C536
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ribonuclease N1/T1 family.
messages: Secreted

2041044:CPZ25 RS08880
gene id: 2041044:CPZ25_RS08880
uniprot id: A0A4P9C9T4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

2041044:CPZ25 RS15580
gene id: 2041044:CPZ25_RS15580
uniprot id: A0A4P9CAR5
names: Similarity
messages: Belongs to the ParB family.

2041044:CPZ25 RS08080
gene id: 2041044:CPZ25_RS08080
uniprot id: A0A4P9C959
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

2041044:CPZ25 RS09955
gene id: 2041044:CPZ25_RS09955
uniprot id: A0A4P9C839
names: Similarity
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.

2041044:CPZ25 RS01315
gene id: 2041044:CPZ25_RS01315
uniprot id: A0A4P9C453
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

2041044:CPZ25 RS06050
gene id: 2041044:CPZ25_RS06050
uniprot id: A0A4P9C694
names: Function
names: Similarity
messages: Belongs to the flavodoxin family.
messages: Low-potential electron donor to a number of redox enzymes.

2041044:CPZ25 RS18835
gene id: 2041044:CPZ25_RS18835
uniprot id: A0A4P9CEY8
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

2041044:CPZ25 RS15715
gene id: 2041044:CPZ25_RS15715
uniprot id: A0A4P9CAX1
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

2041044:CPZ25 RS01445
gene id: 2041044:CPZ25_RS01445
uniprot id: A0A4P9C426
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

2041044:CPZ25 RS20185
gene id: 2041044:CPZ25_RS20185
uniprot id: A0A4P9CD14
names: Function
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family. Butyryl-CoA CoA-transferase subfamily.
messages: Coenzyme A-transferase that converts butyryl-CoA to butyrate.

2041044:CPZ25 RS19205
gene id: 2041044:CPZ25_RS19205
uniprot id: A0A4P9CCR6
names: Cofactor
names: Similarity
messages: Belongs to the iron-containing alcohol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.

2041044:CPZ25 RS04680
gene id: 2041044:CPZ25_RS04680
uniprot id: A0A2A5TA59
names: Similarity
messages: Belongs to the SorC transcriptional regulatory family.

2041044:CPZ25 RS11795
gene id: 2041044:CPZ25_RS11795
uniprot id: A0A4P9C8Z3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0182 family.
messages: Cell membrane

2041044:CPZ25 RS18650
gene id: 2041044:CPZ25_RS18650
uniprot id: A0A4P9CC81
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

2041044:CPZ25 RS18665
gene id: 2041044:CPZ25_RS18665
uniprot id: A0A4P9CCC4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
messages: Consists of three domains: the N-terminal catalytic domain, the anticodon-binding domain and the C-terminal extension.
messages: Cytoplasm
messages: Homodimer.

2041044:CPZ25 RS00235
gene id: 2041044:CPZ25_RS00235
uniprot id: A0A4P9C3H0
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

2041044:CPZ25 RS10380
gene id: 2041044:CPZ25_RS10380
uniprot id: A0A4P9CA82
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

2041044:CPZ25 RS13020
gene id: 2041044:CPZ25_RS13020
uniprot id: A0A4V1GM67
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

2041044:CPZ25 RS18265
gene id: 2041044:CPZ25_RS18265
uniprot id: A0A4P9CE60
names: Similarity
messages: Belongs to the trimethylamine methyltransferase family.

2041044:CPZ25 RS07465
gene id: 2041044:CPZ25_RS07465
uniprot id: A0A4P9C6Z2
names: Similarity
messages: Belongs to the SorC transcriptional regulatory family.

2041044:CPZ25 RS08900
gene id: 2041044:CPZ25_RS08900
uniprot id: A0A4V1GLZ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
messages: Cytoplasm
messages: Homodimer. Forms a heterotetramer with IscU, interacts with other sulfur acceptors.
messages: Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.

2041044:CPZ25 RS17175
gene id: 2041044:CPZ25_RS17175
uniprot id: A0A4P9CE68
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

2041044:CPZ25 RS10315
gene id: 2041044:CPZ25_RS10315
uniprot id: A0A4P9C836
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.
messages: Cytoplasm
messages: Monomer.

2041044:CPZ25 RS02855
gene id: 2041044:CPZ25_RS02855
uniprot id: A0A4P9C6J1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family.
messages: Membrane

2041044:CPZ25 RS13810
gene id: 2041044:CPZ25_RS13810
uniprot id: A0A4P9CBZ6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

2041044:CPZ25 RS10675
gene id: 2041044:CPZ25_RS10675
uniprot id: A0A4V1GM23
names: Similarity
messages: Belongs to the trimethylamine methyltransferase family.

2041044:CPZ25 RS09160
gene id: 2041044:CPZ25_RS09160
uniprot id: A0A4P9C7J8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2041044:CPZ25 RS09740
gene id: 2041044:CPZ25_RS09740
uniprot id: A0A4P9C804
names: Similarity
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.

2041044:CPZ25 RS19195
gene id: 2041044:CPZ25_RS19195
uniprot id: A0A4P9CEL9
names: Similarity
messages: Belongs to the BMP lipoprotein family.

2041044:CPZ25 RS13215
gene id: 2041044:CPZ25_RS13215
uniprot id: A0A4P9CBQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

2041044:CPZ25 RS16285
gene id: 2041044:CPZ25_RS16285
uniprot id: A0A4P9CD46
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

2041044:CPZ25 RS05440
gene id: 2041044:CPZ25_RS05440
uniprot id: A0A4P9C5Z4
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

2041044:CPZ25 RS12490
gene id: 2041044:CPZ25_RS12490
uniprot id: A0A4P9CBC1
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

2041044:CPZ25 RS17825
gene id: 2041044:CPZ25_RS17825
uniprot id: A0A4P9CBZ7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

2041044:CPZ25 RS11240
gene id: 2041044:CPZ25_RS11240
uniprot id: A0A4P9C8R3
names: Subcellular Location Annotation
messages: Membrane

2041044:CPZ25 RS16840
gene id: 2041044:CPZ25_RS16840
uniprot id: A0A4P9CBN8
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.

2041044:CPZ25 RS17180
gene id: 2041044:CPZ25_RS17180
uniprot id: A0A4P9CBU7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of alpha-methyl-L-serine to D-alanine with tetrahydrofolate (THF) serving as the one-carbon carrier.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2041044:CPZ25 RS18340
gene id: 2041044:CPZ25_RS18340
uniprot id: A0A4P9CE18
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvB family.
messages: Forms a complex with RuvA.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.

2041044:CPZ25 RS19100
gene id: 2041044:CPZ25_RS19100
uniprot id: A0A4P9CF31
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

2041044:CPZ25 RS19145
gene id: 2041044:CPZ25_RS19145
uniprot id: A0A4P9CEL0
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

2041044:CPZ25 RS18440
gene id: 2041044:CPZ25_RS18440
uniprot id: A0A4P9CE35
names: Function
names: Similarity
messages: Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Belongs to the organic radical-activating enzymes family.

2041044:CPZ25 RS13015
gene id: 2041044:CPZ25_RS13015
uniprot id: A0A4P9CBL2
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

2041044:CPZ25 RS11930
gene id: 2041044:CPZ25_RS11930
uniprot id: A0A4P9C985
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the PRA-PH family.
messages: In the N-terminal section; belongs to the PRA-CH family.

2041044:CPZ25 RS11020
gene id: 2041044:CPZ25_RS11020
uniprot id: A0A4P9C8U5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

2041044:CPZ25 RS19750
gene id: 2041044:CPZ25_RS19750
uniprot id: A0A4P9CEY0
names: Similarity
messages: Belongs to the FPG family.

2041044:CPZ25 RS14285
gene id: 2041044:CPZ25_RS14285
uniprot id: A0A4P9CA34
names: Subcellular Location Annotation
messages: Membrane

2041044:CPZ25 RS14495
gene id: 2041044:CPZ25_RS14495
uniprot id: A0A4P9CA96
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

2041044:CPZ25 RS17885
gene id: 2041044:CPZ25_RS17885
uniprot id: A0A4P9CBU5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transcriptional regulatory Rex family.
messages: Cytoplasm
messages: Homodimer.
messages: Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.

2041044:CPZ25 RS01735
gene id: 2041044:CPZ25_RS01735
uniprot id: A0A4P9C676
names: Function
names: Similarity
messages: Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PDRP subfamily.
messages: Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation.

2041044:CPZ25 RS06675
gene id: 2041044:CPZ25_RS06675
uniprot id: A0A4P9C8R9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2041044:CPZ25 RS10400
gene id: 2041044:CPZ25_RS10400
uniprot id: A0A4P9CAB9
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

2041044:CPZ25 RS18350
gene id: 2041044:CPZ25_RS18350
uniprot id: A0A4P9CC77
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

2041044:CPZ25 RS10360
gene id: 2041044:CPZ25_RS10360
uniprot id: A0A4P9C8B4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

2041044:CPZ25 RS12440
gene id: 2041044:CPZ25_RS12440
uniprot id: A0A4P9CBB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

2041044:CPZ25 RS15515
gene id: 2041044:CPZ25_RS15515
uniprot id: A0A4P9CAR3
names: Similarity
messages: Belongs to the UPF0047 family.

2041044:CPZ25 RS06130
gene id: 2041044:CPZ25_RS06130
uniprot id: A0A4P9C8G9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sirtuin family. Class U subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form.

2041044:CPZ25 RS02790
gene id: 2041044:CPZ25_RS02790
uniprot id: A0A4P9CCY9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

2041044:CPZ25 RS13395
gene id: 2041044:CPZ25_RS13395
uniprot id: A0A4P9C9M8
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

2041044:CPZ25 RS16835
gene id: 2041044:CPZ25_RS16835
uniprot id: A0A4P9CE13
names: Similarity
messages: Belongs to the sigma-70 factor family.

2041044:CPZ25 RS06570
gene id: 2041044:CPZ25_RS06570
uniprot id: A0A4P9C8Q0
names: Similarity
messages: Belongs to the CvfB family.

2041044:CPZ25 RS00145
gene id: 2041044:CPZ25_RS00145
uniprot id: A0A4V1GLH2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

2041044:CPZ25 RS19705
gene id: 2041044:CPZ25_RS19705
uniprot id: A0A4P9CCU0
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

2041044:CPZ25 RS18635
gene id: 2041044:CPZ25_RS18635
uniprot id: A0A4P9CEC4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

2041044:CPZ25 RS13070
gene id: 2041044:CPZ25_RS13070
uniprot id: A0A4V1GM68
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

2041044:CPZ25 RS14430
gene id: 2041044:CPZ25_RS14430
uniprot id: A0A4P9CCB3
names: Function
messages: Component of the dihydroxyacetone kinase complex, which is responsible for the phosphoenolpyruvate (PEP)-dependent phosphorylation of dihydroxyacetone. DhaM serves as the phosphoryl donor. Is phosphorylated by phosphoenolpyruvate in an EI- and HPr-dependent reaction, and a phosphorelay system on histidine residues finally leads to phosphoryl transfer to DhaL and dihydroxyacetone.

2041044:CPZ25 RS04415
gene id: 2041044:CPZ25_RS04415
uniprot id: A0A4P9C5P5
names: Similarity
messages: Belongs to the V-ATPase F subunit family.

2041044:CPZ25 RS15035
gene id: 2041044:CPZ25_RS15035
uniprot id: A0A4P9CAK0
names: Similarity
messages: Belongs to the FGGY kinase family.

2041044:CPZ25 RS18310
gene id: 2041044:CPZ25_RS18310
uniprot id: A0A4P9CBZ3
names: Similarity
messages: Belongs to the alpha-acetolactate decarboxylase family.

2041044:CPZ25 RS13280
gene id: 2041044:CPZ25_RS13280
uniprot id: A0A4P9C9L6
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

2041044:CPZ25 RS13675
gene id: 2041044:CPZ25_RS13675
uniprot id: A0A4P9CA02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

2041044:CPZ25 RS12980
gene id: 2041044:CPZ25_RS12980
uniprot id: A0A4P9C9C1
names: Similarity
messages: Belongs to the thioredoxin family.

2041044:CPZ25 RS10290
gene id: 2041044:CPZ25_RS10290
uniprot id: A0A4P9C8H4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

2041044:CPZ25 RS07720
gene id: 2041044:CPZ25_RS07720
uniprot id: A0A4P9C8Y5
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2041044:CPZ25 RS09860
gene id: 2041044:CPZ25_RS09860
uniprot id: A0A4P9CAA8
names: Subcellular Location Annotation
messages: Membrane

2041044:CPZ25 RS01595
gene id: 2041044:CPZ25_RS01595
uniprot id: A0A4P9C3V0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

2041044:CPZ25 RS11915
gene id: 2041044:CPZ25_RS11915
uniprot id: A0A4P9CB03
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

2041044:CPZ25 RS11895
gene id: 2041044:CPZ25_RS11895
uniprot id: A0A4P9C909
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Lacks the C-terminal regulatory region which is replaced by HisZ.

2041044:CPZ25 RS08350
gene id: 2041044:CPZ25_RS08350
uniprot id: A0A4P9C7K3
names: Function
names: Similarity
messages: Belongs to the WhiA family.
messages: Involved in cell division and chromosome segregation.

2041044:CPZ25 RS20105
gene id: 2041044:CPZ25_RS20105
uniprot id: A0A4P9CF02
names: Similarity
messages: Belongs to the UPF0102 family.

2041044:CPZ25 RS00910
gene id: 2041044:CPZ25_RS00910
uniprot id: A0A4P9C3I1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Catalyzes the sodium-dependent uptake of extracellular L-proline.
messages: Cell membrane
messages: Membrane

2041044:CPZ25 RS00365
gene id: 2041044:CPZ25_RS00365
uniprot id: A0A4P9C3F2
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

2041044:CPZ25 RS04885
gene id: 2041044:CPZ25_RS04885
uniprot id: A0A2A5TA17
names: Subcellular Location Annotation
messages: Membrane

2041044:CPZ25 RS05375
gene id: 2041044:CPZ25_RS05375
uniprot id: A0A4P9C5Q7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RnfG family.
messages: Cell membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

2041044:CPZ25 RS00795
gene id: 2041044:CPZ25_RS00795
uniprot id: A0A4P9C5S2
names: Similarity
messages: Belongs to the KdgT transporter family.

2041044:CPZ25 RS08855
gene id: 2041044:CPZ25_RS08855
uniprot id: A0A4P9C7E6
names: Similarity
messages: Belongs to the UPF0473 family.

2041044:CPZ25 RS00285
gene id: 2041044:CPZ25_RS00285
uniprot id: A0A4P9C3I0
names: Similarity
messages: Belongs to the aldolase class II family. AraD/FucA subfamily.

2041044:CPZ25 RS11055
gene id: 2041044:CPZ25_RS11055
uniprot id: A0A4P9CAW9
names: Subcellular Location Annotation
messages: Membrane

2041044:CPZ25 RS08950
gene id: 2041044:CPZ25_RS08950
uniprot id: A0A4V1GLZ1
names: Similarity
messages: Belongs to the thioredoxin family.

2041044:CPZ25 RS20245
gene id: 2041044:CPZ25_RS20245
uniprot id: A0A4P9CCV5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2041044:CPZ25 RS15110
gene id: 2041044:CPZ25_RS15110
uniprot id: A0A4P9CAX2
names: Similarity
messages: Belongs to the UPF0145 family.

2041044:CPZ25 RS17095
gene id: 2041044:CPZ25_RS17095
uniprot id: A0A4V1GME4
names: Similarity
messages: Belongs to the FGGY kinase family.

2041044:CPZ25 RS03490
gene id: 2041044:CPZ25_RS03490
uniprot id: A0A4P9C564
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

2041044:CPZ25 RS02470
gene id: 2041044:CPZ25_RS02470
uniprot id: A0A4P9C4C3
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family. N(4) subfamily.

2041044:CPZ25 RS10760
gene id: 2041044:CPZ25_RS10760
uniprot id: A0A4P9C8Q2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

2041044:CPZ25 RS13905
gene id: 2041044:CPZ25_RS13905
uniprot id: A0A4P9CA21
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

2041044:CPZ25 RS11025
gene id: 2041044:CPZ25_RS11025
uniprot id: A0A4P9CAM2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

2041044:CPZ25 RS17810
gene id: 2041044:CPZ25_RS17810
uniprot id: A0A4P9CBU6
names: Similarity
messages: Belongs to the trimethylamine methyltransferase family.

2041044:CPZ25 RS12575
gene id: 2041044:CPZ25_RS12575
uniprot id: A0A4P9C9A5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

2041044:CPZ25 RS00550
gene id: 2041044:CPZ25_RS00550
uniprot id: A0A4V1GLI0
names: Similarity
messages: Belongs to the RelB/DinJ antitoxin family.

2041044:CPZ25 RS08420
gene id: 2041044:CPZ25_RS08420
uniprot id: A0A4P9C777
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpC family.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

2041044:CPZ25 RS03905
gene id: 2041044:CPZ25_RS03905
uniprot id: A0A4P9C7C4
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

2041044:CPZ25 RS18645
gene id: 2041044:CPZ25_RS18645
uniprot id: A0A4P9CCG9
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

2041044:CPZ25 RS09545
gene id: 2041044:CPZ25_RS09545
uniprot id: A0A2A5T8C3
names: Similarity
messages: Belongs to the DEAD box helicase family.

2041044:CPZ25 RS13470
gene id: 2041044:CPZ25_RS13470
uniprot id: A0A4P9CBV1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

2041044:CPZ25 RS00800
gene id: 2041044:CPZ25_RS00800
uniprot id: A0A4V1GLI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

2041044:CPZ25 RS09060
gene id: 2041044:CPZ25_RS09060
uniprot id: A0A4P9C9Q8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2041044:CPZ25 RS04520
gene id: 2041044:CPZ25_RS04520
uniprot id: A0A2A5TGF1
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily.

2041044:CPZ25 RS20090
gene id: 2041044:CPZ25_RS20090
uniprot id: A0A4P9CCZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Cell membrane
messages: Membrane

2041044:CPZ25 RS18315
gene id: 2041044:CPZ25_RS18315
uniprot id: A0A4P9CE69
names: Subcellular Location Annotation
messages: Membrane

2041044:CPZ25 RS03360
gene id: 2041044:CPZ25_RS03360
uniprot id: A0A4P9C4Y7
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit.

2041044:CPZ25 RS02895
gene id: 2041044:CPZ25_RS02895
uniprot id: A0A4P9C4J1
names: Similarity
messages: Belongs to the CinA family.

2041044:CPZ25 RS05455
gene id: 2041044:CPZ25_RS05455
uniprot id: A0A4P9C602
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

2041044:CPZ25 RS10255
gene id: 2041044:CPZ25_RS10255
uniprot id: A0A4P9C827
names: Subcellular Location Annotation
messages: Membrane

2041044:CPZ25 RS16510
gene id: 2041044:CPZ25_RS16510
uniprot id: A0A4P9CB88
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

2041044:CPZ25 RS15165
gene id: 2041044:CPZ25_RS15165
uniprot id: A0A4P9CAY1
names: Similarity
messages: Belongs to the EamA transporter family.

2041044:CPZ25 RS12880
gene id: 2041044:CPZ25_RS12880
uniprot id: A0A4P9C9A3
names: Cofactor
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Binds 1 Fe(3+) ion per subunit.

2041044:CPZ25 RS10515
gene id: 2041044:CPZ25_RS10515
uniprot id: A0A4V1GM20
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

2041044:CPZ25 RS05280
gene id: 2041044:CPZ25_RS05280
uniprot id: A0A4P9C5X0
names: Similarity
messages: Belongs to the band 7/mec-2 family.

2041044:CPZ25 RS19085
gene id: 2041044:CPZ25_RS19085
uniprot id: A0A4P9CCE3
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

2041044:CPZ25 RS04700
gene id: 2041044:CPZ25_RS04700
uniprot id: A0A2A5T9X4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

2041044:CPZ25 RS09965
gene id: 2041044:CPZ25_RS09965
uniprot id: A0A4P9CAC6
names: Similarity
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.

2041044:CPZ25 RS16745
gene id: 2041044:CPZ25_RS16745
uniprot id: A0A4P9CBE1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DcuC/DcuD transporter (TC 2.A.61) family.
messages: Membrane

2041044:CPZ25 RS12890
gene id: 2041044:CPZ25_RS12890
uniprot id: A0A4P9C9F1
names: Similarity
messages: Belongs to the trimethylamine methyltransferase family.

2041044:CPZ25 RS06555
gene id: 2041044:CPZ25_RS06555
uniprot id: A0A4P9C6H8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

2041044:CPZ25 RS05985
gene id: 2041044:CPZ25_RS05985
uniprot id: A0A4P9C8D6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

2041044:CPZ25 RS00535
gene id: 2041044:CPZ25_RS00535
uniprot id: A0A4P9C3M2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

2041044:CPZ25 RS05420
gene id: 2041044:CPZ25_RS05420
uniprot id: A0A4P9C5Y2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the encapsulin family. Family 1 subfamily.
messages: Encapsulin nanocompartment

2041044:CPZ25 RS08505
gene id: 2041044:CPZ25_RS08505
uniprot id: A0A4P9C9D4
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

2041044:CPZ25 RS10410
gene id: 2041044:CPZ25_RS10410
uniprot id: A0A4P9C8C2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

2041044:CPZ25 RS10245
gene id: 2041044:CPZ25_RS10245
uniprot id: A0A4V1GM15
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

2041044:CPZ25 RS03335
gene id: 2041044:CPZ25_RS03335
uniprot id: A0A4V1GLN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase proteolipid subunit family.
messages: Membrane

2041044:CPZ25 RS12380
gene id: 2041044:CPZ25_RS12380
uniprot id: A0A4P9C9M2
names: Similarity
messages: Belongs to the UPF0178 family.

2041044:CPZ25 RS08430
gene id: 2041044:CPZ25_RS08430
uniprot id: A0A4P9C7E1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpA family.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds the extracellular potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

2041044:CPZ25 RS17790
gene id: 2041044:CPZ25_RS17790
uniprot id: A0A4P9CBR0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

2041044:CPZ25 RS10265
gene id: 2041044:CPZ25_RS10265
uniprot id: A0A4P9CD29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane

2041044:CPZ25 RS06180
gene id: 2041044:CPZ25_RS06180
uniprot id: A0A4P9C643
names: Similarity
messages: Belongs to the trimethylamine methyltransferase family.

2041044:CPZ25 RS08370
gene id: 2041044:CPZ25_RS08370
uniprot id: A0A4P9C768
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

2041044:CPZ25 RS15320
gene id: 2041044:CPZ25_RS15320
uniprot id: A0A4P9CDA5
names: Similarity
messages: Belongs to the phosphohexose mutase family.

2041044:CPZ25 RS10490
gene id: 2041044:CPZ25_RS10490
uniprot id: A0A4P9CAA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

2041044:CPZ25 RS04505
gene id: 2041044:CPZ25_RS04505
uniprot id: A0A2A5TA13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

2041044:CPZ25 RS10365
gene id: 2041044:CPZ25_RS10365
uniprot id: A0A4P9C847
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

2041044:CPZ25 RS17355
gene id: 2041044:CPZ25_RS17355
uniprot id: A0A4V1GME9
names: Similarity
messages: Belongs to the EamA transporter family.

2041044:CPZ25 RS13350
gene id: 2041044:CPZ25_RS13350
uniprot id: A0A4P9CBR2
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

2041044:CPZ25 RS04420
gene id: 2041044:CPZ25_RS04420
uniprot id: A0A4P9C7M0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase proteolipid subunit family.
messages: Membrane

2041044:CPZ25 RS12755
gene id: 2041044:CPZ25_RS12755
uniprot id: A0A4P9CBG7
names: Similarity
messages: Belongs to the FGGY kinase family.

2041044:CPZ25 RS01605
gene id: 2041044:CPZ25_RS01605
uniprot id: A0A4P9C449
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

2041044:CPZ25 RS11250
gene id: 2041044:CPZ25_RS11250
uniprot id: A0A4P9C8N3
names: Similarity
messages: Belongs to the trimethylamine methyltransferase family.

2041044:CPZ25 RS09720
gene id: 2041044:CPZ25_RS09720
uniprot id: A0A4V1GM05
names: Subcellular Location Annotation
messages: Membrane

2041044:CPZ25 RS10415
gene id: 2041044:CPZ25_RS10415
uniprot id: A0A4P9C855
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

2041044:CPZ25 RS09170
gene id: 2041044:CPZ25_RS09170
uniprot id: A0A4P9C9L8
names: Similarity
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.

2041044:CPZ25 RS18840
gene id: 2041044:CPZ25_RS18840
uniprot id: A0A4P9CCK5
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

2041044:CPZ25 RS17830
gene id: 2041044:CPZ25_RS17830
uniprot id: A0A4P9CBS6
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

2041044:CPZ25 RS14090
gene id: 2041044:CPZ25_RS14090
uniprot id: A0A4P9CAE7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

2041044:CPZ25 RS05965
gene id: 2041044:CPZ25_RS05965
uniprot id: A0A4P9C821
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

2041044:CPZ25 RS17700
gene id: 2041044:CPZ25_RS17700
uniprot id: A0A4P9CED9
names: Subcellular Location Annotation
messages: Membrane

2041044:CPZ25 RS10385
gene id: 2041044:CPZ25_RS10385
uniprot id: A0A4P9CAJ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

2041044:CPZ25 RS19095
gene id: 2041044:CPZ25_RS19095
uniprot id: A0A4P9CEK1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2041044:CPZ25 RS10405
gene id: 2041044:CPZ25_RS10405
uniprot id: A0A4V1GM18
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

2041044:CPZ25 RS04715
gene id: 2041044:CPZ25_RS04715
uniprot id: A0A2A5TAB1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

2041044:CPZ25 RS01145
gene id: 2041044:CPZ25_RS01145
uniprot id: A0A4P9C5X6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

2041044:CPZ25 RS01140
gene id: 2041044:CPZ25_RS01140
uniprot id: A0A4P9C5Q0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

2041044:CPZ25 RS05475
gene id: 2041044:CPZ25_RS05475
uniprot id: A0A4P9C5Z1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

2041044:CPZ25 RS05315
gene id: 2041044:CPZ25_RS05315
uniprot id: A0A4P9C5W5
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.

2041044:CPZ25 RS06480
gene id: 2041044:CPZ25_RS06480
uniprot id: A0A4P9C6G6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

2041044:CPZ25 RS04870
gene id: 2041044:CPZ25_RS04870
uniprot id: A0A2A5TG81
names: Similarity
messages: Belongs to the UPF0749 family.

2041044:CPZ25 RS03180
gene id: 2041044:CPZ25_RS03180
uniprot id: A0A4P9C700
names: Subcellular Location Annotation
messages: Membrane

2041044:CPZ25 RS10355
gene id: 2041044:CPZ25_RS10355
uniprot id: A0A4V1GM17
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

2041044:CPZ25 RS07235
gene id: 2041044:CPZ25_RS07235
uniprot id: A0A4P9C6T4
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

2041044:CPZ25 RS09125
gene id: 2041044:CPZ25_RS09125
uniprot id: A0A4P9C9X5
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

2041044:CPZ25 RS06545
gene id: 2041044:CPZ25_RS06545
uniprot id: A0A4P9C6A9
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

2041044:CPZ25 RS05320
gene id: 2041044:CPZ25_RS05320
uniprot id: A0A4P9C5M6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate.
messages: Homotrimer.

2041044:CPZ25 RS17760
gene id: 2041044:CPZ25_RS17760
uniprot id: A0A4P9CBT5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

2041044:CPZ25 RS12585
gene id: 2041044:CPZ25_RS12585
uniprot id: A0A4P9CBM3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

2041044:CPZ25 RS14345
gene id: 2041044:CPZ25_RS14345
uniprot id: A0A4P9CA83
names: Cofactor
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Binds 1 Fe(3+) ion per subunit.

2041044:CPZ25 RS04920
gene id: 2041044:CPZ25_RS04920
uniprot id: A0A2A5TAF5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

2041044:CPZ25 RS18660
gene id: 2041044:CPZ25_RS18660
uniprot id: A0A4V1GMH2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

2041044:CPZ25 RS02805
gene id: 2041044:CPZ25_RS02805
uniprot id: A0A4P9C6I2
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

2041044:CPZ25 RS13945
gene id: 2041044:CPZ25_RS13945
uniprot id: A0A4P9C9Y0
names: Subcellular Location Annotation
messages: Membrane

2041044:CPZ25 RS02390
gene id: 2041044:CPZ25_RS02390
uniprot id: A0A4P9C4I3
names: Function
names: Similarity
messages: Abolishes the inhibitory effect of tetracyclin on protein synthesis by a non-covalent modification of the ribosomes.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.

2041044:CPZ25 RS03350
gene id: 2041044:CPZ25_RS03350
uniprot id: A0A4P9C4R3
names: Similarity
messages: Belongs to the V-ATPase F subunit family.

2041044:CPZ25 RS13040
gene id: 2041044:CPZ25_RS13040
uniprot id: A0A4P9C9G9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glutaminase PdxT/SNO family.
messages: Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.
messages: In the presence of PdxS, forms a dodecamer of heterodimers. Only shows activity in the heterodimer.

2041044:CPZ25 RS17820
gene id: 2041044:CPZ25_RS17820
uniprot id: A0A4V1GMF6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

2041044:CPZ25 RS09525
gene id: 2041044:CPZ25_RS09525
uniprot id: A0A2A5TCM8
names: Function
names: Similarity
messages: Belongs to the desulfoferrodoxin family.
messages: Catalyzes the one-electron reduction of superoxide anion radical to hydrogen peroxide at a nonheme ferrous iron center. Plays a fundamental role in case of oxidative stress via its superoxide detoxification activity.

2041044:CPZ25 RS18775
gene id: 2041044:CPZ25_RS18775
uniprot id: A0A4P9CC69
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

2041044:CPZ25 RS05880
gene id: 2041044:CPZ25_RS05880
uniprot id: A0A2A5T8I2
names: Similarity
messages: Belongs to the trimethylamine methyltransferase family.

2041044:CPZ25 RS09135
gene id: 2041044:CPZ25_RS09135
uniprot id: A0A4P9C7W6
names: Subcellular Location Annotation
messages: Membrane

2041044:CPZ25 RS04855
gene id: 2041044:CPZ25_RS04855
uniprot id: A0A2A5T9U2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

2041044:CPZ25 RS18380
gene id: 2041044:CPZ25_RS18380
uniprot id: A0A4P9CCC2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

2041044:CPZ25 RS18280
gene id: 2041044:CPZ25_RS18280
uniprot id: A0A4P9CC21
names: Similarity
messages: Belongs to the EamA transporter family.

2041044:CPZ25 RS11815
gene id: 2041044:CPZ25_RS11815
uniprot id: A0A4P9CAY5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

2041044:CPZ25 RS19180
gene id: 2041044:CPZ25_RS19180
uniprot id: A0A4P9CCK3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of glycine to tRNA(Gly).
messages: Cytoplasm
messages: Homodimer.

2041044:CPZ25 RS15040
gene id: 2041044:CPZ25_RS15040
uniprot id: A0A4P9CAI2
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

2041044:CPZ25 RS08190
gene id: 2041044:CPZ25_RS08190
uniprot id: A0A4P9C979
names: Similarity
messages: Belongs to the SAICAR synthetase family.

2041044:CPZ25 RS09685
gene id: 2041044:CPZ25_RS09685
uniprot id: A0A4P9C7W0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

2041044:CPZ25 RS15140
gene id: 2041044:CPZ25_RS15140
uniprot id: A0A4P9CAJ8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

2041044:CPZ25 RS12660
gene id: 2041044:CPZ25_RS12660
uniprot id: A0A4P9C9D2
names: Similarity
messages: Belongs to the peptidase S66 family.

2041044:CPZ25 RS17285
gene id: 2041044:CPZ25_RS17285
uniprot id: A0A4P9CDL5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

2041044:CPZ25 RS10640
gene id: 2041044:CPZ25_RS10640
uniprot id: A0A4P9C8C6
names: Subcellular Location Annotation
messages: Bacterial microcompartment

2041044:CPZ25 RS01620
gene id: 2041044:CPZ25_RS01620
uniprot id: A0A4P9C452
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

2041044:CPZ25 RS12685
gene id: 2041044:CPZ25_RS12685
uniprot id: A0A4P9CBP1
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

2041044:CPZ25 RS00230
gene id: 2041044:CPZ25_RS00230
uniprot id: A0A4P9C5F8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

2041044:CPZ25 RS04795
gene id: 2041044:CPZ25_RS04795
uniprot id: A0A2A5TA18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

2041044:CPZ25 RS04220
gene id: 2041044:CPZ25_RS04220
uniprot id: A0A4P9C5J5
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

2041044:CPZ25 RS06250
gene id: 2041044:CPZ25_RS06250
uniprot id: A0A4P9C6E2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FNT transporter (TC 2.A.44) family.
messages: Membrane

2041044:CPZ25 RS08575
gene id: 2041044:CPZ25_RS08575
uniprot id: A0A4P9C9I6
names: Subcellular Location Annotation
messages: Membrane

2041044:CPZ25 RS10330
gene id: 2041044:CPZ25_RS10330
uniprot id: A0A4P9CA77
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

2041044:CPZ25 RS16335
gene id: 2041044:CPZ25_RS16335
uniprot id: A0A4P9CD53
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of alpha-methyl-L-serine to D-alanine with tetrahydrofolate (THF) serving as the one-carbon carrier.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2041044:CPZ25 RS17310
gene id: 2041044:CPZ25_RS17310
uniprot id: A0A4P9CBJ1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

2041044:CPZ25 RS07765
gene id: 2041044:CPZ25_RS07765
uniprot id: A0A4P9C6W5
names: Function
messages: Component of the dihydroxyacetone kinase complex, which is responsible for the phosphoenolpyruvate (PEP)-dependent phosphorylation of dihydroxyacetone. DhaM serves as the phosphoryl donor. Is phosphorylated by phosphoenolpyruvate in an EI- and HPr-dependent reaction, and a phosphorelay system on histidine residues finally leads to phosphoryl transfer to DhaL and dihydroxyacetone.

2041044:CPZ25 RS20060
gene id: 2041044:CPZ25_RS20060
uniprot id: A0A4P9CD44
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A probable RNA chaperone. Forms a complex with KhpB which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm
messages: Forms a complex with KhpB.

2041044:CPZ25 RS13535
gene id: 2041044:CPZ25_RS13535
uniprot id: A0A4P9C9R3
names: Similarity
messages: Belongs to the trimethylamine methyltransferase family.

2041044:CPZ25 RS16770
gene id: 2041044:CPZ25_RS16770
uniprot id: A0A4P9CBD5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

2041044:CPZ25 RS05310
gene id: 2041044:CPZ25_RS05310
uniprot id: A0A4V1GLS2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThiI family.
messages: Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
messages: Cytoplasm

2041044:CPZ25 RS08425
gene id: 2041044:CPZ25_RS08425
uniprot id: A0A4P9C782
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system and for the release of the potassium ions to the cytoplasm.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

2041044:CPZ25 RS06665
gene id: 2041044:CPZ25_RS06665
uniprot id: A0A4P9C6J6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2041044:CPZ25 RS13380
gene id: 2041044:CPZ25_RS13380
uniprot id: A0A4P9C9N5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

2041044:CPZ25 RS08100
gene id: 2041044:CPZ25_RS08100
uniprot id: A0A4P9C7A2
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

2041044:CPZ25 RS07590
gene id: 2041044:CPZ25_RS07590
uniprot id: A0A4V1GLW5
names: Similarity
names: Subunit
messages: Belongs to the RNase H family.
messages: Monomer.

2041044:CPZ25 RS04515
gene id: 2041044:CPZ25_RS04515
uniprot id: A0A2A5TA81
names: Similarity
messages: Belongs to the carbamate kinase family.

2041044:CPZ25 RS03300
gene id: 2041044:CPZ25_RS03300
uniprot id: A0A4P9C4Q6
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2041044:CPZ25 RS18965
gene id: 2041044:CPZ25_RS18965
uniprot id: A0A4P9CEJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

2041044:CPZ25 RS01350
gene id: 2041044:CPZ25_RS01350
uniprot id: A0A4P9C5T3
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

2041044:CPZ25 RS06245
gene id: 2041044:CPZ25_RS06245
uniprot id: A0A4P9C8I9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2041044:CPZ25 RS11135
gene id: 2041044:CPZ25_RS11135
uniprot id: A0A4P9C8H7
names: Similarity
messages: Belongs to the glutamine synthetase family.

2041044:CPZ25 RS17275
gene id: 2041044:CPZ25_RS17275
uniprot id: A0A4P9CBW8
names: Similarity
messages: Belongs to the EutP/PduV family.

2041044:CPZ25 RS18885
gene id: 2041044:CPZ25_RS18885
uniprot id: A0A4P9CEG4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

2041044:CPZ25 RS10345
gene id: 2041044:CPZ25_RS10345
uniprot id: A0A4P9C8I4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

2041044:CPZ25 RS02935
gene id: 2041044:CPZ25_RS02935
uniprot id: A0A4V1GLM6
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

2041044:CPZ25 RS10340
gene id: 2041044:CPZ25_RS10340
uniprot id: A0A4P9C8C1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

2041044:CPZ25 RS00355
gene id: 2041044:CPZ25_RS00355
uniprot id: A0A4V1GLH6
names: Subcellular Location Annotation
messages: Cytoplasm

2041044:CPZ25 RS10650
gene id: 2041044:CPZ25_RS10650
uniprot id: A0A4P9CAD1
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

2041044:CPZ25 RS02375
gene id: 2041044:CPZ25_RS02375
uniprot id: A0A4P9C4H7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VirD4/TraG family.
messages: Membrane

2041044:CPZ25 RS20000
gene id: 2041044:CPZ25_RS20000
uniprot id: A0A4P9CFG8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

2041044:CPZ25 RS00135
gene id: 2041044:CPZ25_RS00135
uniprot id: A0A4P9C3J9
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

2041044:CPZ25 RS18335
gene id: 2041044:CPZ25_RS18335
uniprot id: A0A4P9CC26
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

2041044:CPZ25 RS16295
gene id: 2041044:CPZ25_RS16295
uniprot id: A0A4P9CB37
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

2041044:CPZ25 RS08590
gene id: 2041044:CPZ25_RS08590
uniprot id: A0A4P9C7A5
names: Similarity
messages: Belongs to the UPF0246 family.

2041044:CPZ25 RS20120
gene id: 2041044:CPZ25_RS20120
uniprot id: A0A4P9CCW8
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Activated by phosphorylation and inhibited by fructose 1,6-bisphosphate (FBP).
messages: Belongs to the FGGY kinase family.
messages: Homotetramer and homodimer (in equilibrium).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2041044:CPZ25 RS19920
gene id: 2041044:CPZ25_RS19920
uniprot id: A0A4P9CCU1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

2041044:CPZ25 RS01340
gene id: 2041044:CPZ25_RS01340
uniprot id: A0A4P9C3S2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

2041044:CPZ25 RS18630
gene id: 2041044:CPZ25_RS18630
uniprot id: A0A4P9CC45
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

2041044:CPZ25 RS08565
gene id: 2041044:CPZ25_RS08565
uniprot id: A0A4P9C7I2
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

2041044:CPZ25 RS19140
gene id: 2041044:CPZ25_RS19140
uniprot id: A0A4P9CCC5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

2041044:CPZ25 RS08060
gene id: 2041044:CPZ25_RS08060
uniprot id: A0A4P9C774
names: Cofactor
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.

2041044:CPZ25 RS03395
gene id: 2041044:CPZ25_RS03395
uniprot id: A0A4V1GLN5
names: Similarity
messages: Belongs to the serine/threonine dehydratase family.

2041044:CPZ25 RS06705
gene id: 2041044:CPZ25_RS06705
uniprot id: A0A4P9C6K1
names: Similarity
messages: Belongs to the YggT family.

2041044:CPZ25 RS16150
gene id: 2041044:CPZ25_RS16150
uniprot id: A0A4P9CB23
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.

2041044:CPZ25 RS20115
gene id: 2041044:CPZ25_RS20115
uniprot id: A0A4P9CD51
names: Subcellular Location Annotation
messages: Membrane

2041044:CPZ25 RS12855
gene id: 2041044:CPZ25_RS12855
uniprot id: A0A4P9C9U5
names: Similarity
messages: Belongs to the thioredoxin family.

2041044:CPZ25 RS16310
gene id: 2041044:CPZ25_RS16310
uniprot id: A0A4P9CB28
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-stimulated subfamily.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Requires K(+) for maximal activity.
messages: Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na(+) movement across the membrane.

2041044:CPZ25 RS18825
gene id: 2041044:CPZ25_RS18825
uniprot id: A0A4P9CC75
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

2041044:CPZ25 RS13145
gene id: 2041044:CPZ25_RS13145
uniprot id: A0A4P9CBL6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

2041044:CPZ25 RS12120
gene id: 2041044:CPZ25_RS12120
uniprot id: A0A4P9CB40
names: Subcellular Location Annotation
messages: Membrane

2041044:CPZ25 RS13035
gene id: 2041044:CPZ25_RS13035
uniprot id: A0A4P9C9L7
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSP33 family.
messages: Cytoplasm
messages: Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.
messages: Under oxidizing conditions two disulfide bonds are formed involving the reactive cysteines. Under reducing conditions zinc is bound to the reactive cysteines and the protein is inactive.

2041044:CPZ25 RS16305
gene id: 2041044:CPZ25_RS16305
uniprot id: A0A4P9CB49
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

2041044:CPZ25 RS10295
gene id: 2041044:CPZ25_RS10295
uniprot id: A0A4P9CAA2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

2041044:CPZ25 RS06175
gene id: 2041044:CPZ25_RS06175
uniprot id: A0A4P9C637
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

2041044:CPZ25 RS02840
gene id: 2041044:CPZ25_RS02840
uniprot id: A0A4P9C4G3
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

2041044:CPZ25 RS05905
gene id: 2041044:CPZ25_RS05905
uniprot id: A0A2A5T8L3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2041044:CPZ25 RS14635
gene id: 2041044:CPZ25_RS14635
uniprot id: A0A4P9CAE8
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

2041044:CPZ25 RS07320
gene id: 2041044:CPZ25_RS07320
uniprot id: A0A4P9C724
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

2041044:CPZ25 RS09150
gene id: 2041044:CPZ25_RS09150
uniprot id: A0A4P9C7R0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

2041044:CPZ25 RS15945
gene id: 2041044:CPZ25_RS15945
uniprot id: A0A4P9CB09
names: Similarity
messages: Belongs to the plasmid mobilization pre family.

2041044:CPZ25 RS18870
gene id: 2041044:CPZ25_RS18870
uniprot id: A0A4P9CCA9
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

2041044:CPZ25 RS11375
gene id: 2041044:CPZ25_RS11375
uniprot id: A0A4P9C8U8
names: Similarity
messages: Belongs to the peptidase C59 family.

2041044:CPZ25 RS06135
gene id: 2041044:CPZ25_RS06135
uniprot id: A0A4P9C6C6
names: Subcellular Location Annotation
messages: Membrane

2041044:CPZ25 RS10325
gene id: 2041044:CPZ25_RS10325
uniprot id: A0A4P9C8A2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

2041044:CPZ25 RS05380
gene id: 2041044:CPZ25_RS05380
uniprot id: A0A4P9C5Y5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

2041044:CPZ25 RS12900
gene id: 2041044:CPZ25_RS12900
uniprot id: A0A4P9CBT4
names: Subcellular Location Annotation
messages: Membrane

2041044:CPZ25 RS04760
gene id: 2041044:CPZ25_RS04760
uniprot id: A0A2A5TA32
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

2041044:CPZ25 RS16425
gene id: 2041044:CPZ25_RS16425
uniprot id: A0A4P9CDT7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2041044:CPZ25 RS14615
gene id: 2041044:CPZ25_RS14615
uniprot id: A0A4P9CAA3
names: Subcellular Location Annotation
messages: Cytoplasm

2041044:CPZ25 RS11060
gene id: 2041044:CPZ25_RS11060
uniprot id: A0A4P9C8P5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

2041044:CPZ25 RS20030
gene id: 2041044:CPZ25_RS20030
uniprot id: A0A4P9CCY4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

2041044:CPZ25 RS06470
gene id: 2041044:CPZ25_RS06470
uniprot id: A0A4P9C8K9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2041044:CPZ25 RS16340
gene id: 2041044:CPZ25_RS16340
uniprot id: A0A4V1GMC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

2041044:CPZ25 RS04635
gene id: 2041044:CPZ25_RS04635
uniprot id: A0A2A5TA63
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The phosphoryl group from phosphoenolpyruvate (PEP) is transferred to the phosphoryl carrier protein HPr by enzyme I. Phospho-HPr then transfers it to the PTS EIIA domain.

2041044:CPZ25 RS09055
gene id: 2041044:CPZ25_RS09055
uniprot id: A0A4P9C7V7
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

2041044:CPZ25 RS07840
gene id: 2041044:CPZ25_RS07840
uniprot id: A0A4P9C7B1
names: Function
names: Similarity
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids threonine, isoleucine and methionine.

2041044:CPZ25 RS08150
gene id: 2041044:CPZ25_RS08150
uniprot id: A0A4P9C7B2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

2041044:CPZ25 RS07460
gene id: 2041044:CPZ25_RS07460
uniprot id: A0A4P9C951
names: Similarity
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.

2041044:CPZ25 RS11950
gene id: 2041044:CPZ25_RS11950
uniprot id: A0A4P9C8W6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

2041044:CPZ25 RS06010
gene id: 2041044:CPZ25_RS06010
uniprot id: A0A4P9C616
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

2041044:CPZ25 RS09165
gene id: 2041044:CPZ25_RS09165
uniprot id: A0A4P9C7Q3
names: Function
names: Similarity
messages: Belongs to the SpoVG family.
messages: Could be involved in septation.

2041044:CPZ25 RS17085
gene id: 2041044:CPZ25_RS17085
uniprot id: A0A4P9CBJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily.
messages: Cell membrane

2041044:CPZ25 RS19420
gene id: 2041044:CPZ25_RS19420
uniprot id: A0A4P9CF84
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

2041044:CPZ25 RS18180
gene id: 2041044:CPZ25_RS18180
uniprot id: A0A4P9CDZ2
names: Subcellular Location Annotation
messages: Membrane

2041044:CPZ25 RS06335
gene id: 2041044:CPZ25_RS06335
uniprot id: A0A4P9C672
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

2041044:CPZ25 RS14150
gene id: 2041044:CPZ25_RS14150
uniprot id: A0A4P9CC67
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2041044:CPZ25 RS12645
gene id: 2041044:CPZ25_RS12645
uniprot id: A0A4P9C9I1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

2041044:CPZ25 RS18890
gene id: 2041044:CPZ25_RS18890
uniprot id: A0A4P9CEZ6
names: Similarity
messages: Belongs to the leucine-binding protein family.

2041044:CPZ25 RS01115
gene id: 2041044:CPZ25_RS01115
uniprot id: A0A4V1GLJ1
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

2041044:CPZ25 RS16635
gene id: 2041044:CPZ25_RS16635
uniprot id: A0A4P9CBC2
names: Function
names: Similarity
messages: Belongs to the phenylacetyl-CoA ligase family.
messages: Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).

2041044:CPZ25 RS14645
gene id: 2041044:CPZ25_RS14645
uniprot id: A0A4V1GM98
names: Similarity
messages: Belongs to the SorC transcriptional regulatory family.

2041044:CPZ25 RS18975
gene id: 2041044:CPZ25_RS18975
uniprot id: A0A4P9CCH8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

2041044:CPZ25 RS01365
gene id: 2041044:CPZ25_RS01365
uniprot id: A0A4P9C464
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

2041044:CPZ25 RS14455
gene id: 2041044:CPZ25_RS14455
uniprot id: A0A4P9CA97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

2041044:CPZ25 RS11280
gene id: 2041044:CPZ25_RS11280
uniprot id: A0A4P9CAS1
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

2041044:CPZ25 RS03645
gene id: 2041044:CPZ25_RS03645
uniprot id: A0A4P9C778
names: Similarity
messages: Belongs to the citrate synthase family.

2041044:CPZ25 RS08560
gene id: 2041044:CPZ25_RS08560
uniprot id: A0A4P9C9N0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM19 family.
messages: Membrane

2041044:CPZ25 RS13285
gene id: 2041044:CPZ25_RS13285
uniprot id: A0A4P9C9M1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2041044:CPZ25 RS06145
gene id: 2041044:CPZ25_RS06145
uniprot id: A0A4P9CF67
names: Function
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

2041044:CPZ25 RS05270
gene id: 2041044:CPZ25_RS05270
uniprot id: A0A4P9C5M1
names: Similarity
messages: Belongs to the OsmC/Ohr family.

2041044:CPZ25 RS09970
gene id: 2041044:CPZ25_RS09970
uniprot id: A0A4P9C862
names: Similarity
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.

2041044:CPZ25 RS05970
gene id: 2041044:CPZ25_RS05970
uniprot id: A0A4P9C8D8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2041044:CPZ25 RS15820
gene id: 2041044:CPZ25_RS15820
uniprot id: A0A4P9CDI5
names: Similarity
messages: Belongs to the GSP E family.

2041044:CPZ25 RS13345
gene id: 2041044:CPZ25_RS13345
uniprot id: A0A4P9C9M0
names: Similarity
messages: Belongs to the FGGY kinase family.

2041044:CPZ25 RS00440
gene id: 2041044:CPZ25_RS00440
uniprot id: A0A4P9C3K5
names: Similarity
messages: Belongs to the EamA transporter family.

2041044:CPZ25 RS09985
gene id: 2041044:CPZ25_RS09985
uniprot id: A0A4V1GM10
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

2041044:CPZ25 RS03280
gene id: 2041044:CPZ25_RS03280
uniprot id: A0A4P9C715
names: Similarity
messages: Belongs to the PRORSD1 family.

2041044:CPZ25 RS10495
gene id: 2041044:CPZ25_RS10495
uniprot id: A0A4P9CAL5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

2041044:CPZ25 RS14995
gene id: 2041044:CPZ25_RS14995
uniprot id: A0A4P9CCY1
names: Similarity
messages: Belongs to the ycf81 family.

2041044:CPZ25 RS01680
gene id: 2041044:CPZ25_RS01680
uniprot id: A0A4P9C4B8
names: Similarity
messages: Belongs to the class-I fumarase family.

2041044:CPZ25 RS06200
gene id: 2041044:CPZ25_RS06200
uniprot id: A0A4P9C6D5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

2041044:CPZ25 RS04210
gene id: 2041044:CPZ25_RS04210
uniprot id: A0A4P9C7H8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PstS family.
messages: Cell membrane
messages: Involved in the system for phosphate transport across the cytoplasmic membrane.
messages: Membrane
messages: Part of the ABC transporter complex PstSACB involved in phosphate import.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

2041044:CPZ25 RS11715
gene id: 2041044:CPZ25_RS11715
uniprot id: A0A4P9CB84
names: Function
names: Similarity
messages: Belongs to the CheD family.
messages: Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.

2041044:CPZ25 RS05510
gene id: 2041044:CPZ25_RS05510
uniprot id: A0A4P9C691
names: Function
messages: May be involved in the biosynthesis of molybdopterin.

2041044:CPZ25 RS12370
gene id: 2041044:CPZ25_RS12370
uniprot id: A0A4P9CB80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Membrane

2041044:CPZ25 RS03830
gene id: 2041044:CPZ25_RS03830
uniprot id: A0A4P9C566
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TspO/BZRP family.
messages: Membrane

2041044:CPZ25 RS10335
gene id: 2041044:CPZ25_RS10335
uniprot id: A0A4P9CAI4
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

2041044:CPZ25 RS10505
gene id: 2041044:CPZ25_RS10505
uniprot id: A0A4P9C8L2
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

2041044:CPZ25 RS19865
gene id: 2041044:CPZ25_RS19865
uniprot id: A0A4P9CCT2
names: Function
names: Similarity
messages: Belongs to the PduL family.
messages: Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate.

2041044:CPZ25 RS01555
gene id: 2041044:CPZ25_RS01555
uniprot id: A0A4P9C5W8
names: Similarity
messages: Belongs to the glycosyl hydrolase 25 family.

2041044:CPZ25 RS13155
gene id: 2041044:CPZ25_RS13155
uniprot id: A0A4P9C9Z4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

2041044:CPZ25 RS01655
gene id: 2041044:CPZ25_RS01655
uniprot id: A0A4P9C3X5
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

2041044:CPZ25 RS03140
gene id: 2041044:CPZ25_RS03140
uniprot id: A0A4P9C4S7
names: Similarity
messages: Belongs to the UPF0047 family.

2041044:CPZ25 RS09950
gene id: 2041044:CPZ25_RS09950
uniprot id: A0A4P9C807
names: Similarity
messages: Belongs to the FGGY kinase family.

2041044:CPZ25 RS14485
gene id: 2041044:CPZ25_RS14485
uniprot id: A0A4P9CCC3
names: Subcellular Location Annotation
messages: Cell membrane

2041044:CPZ25 RS09775
gene id: 2041044:CPZ25_RS09775
uniprot id: A0A4P9CA28
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

2041044:CPZ25 RS10395
gene id: 2041044:CPZ25_RS10395
uniprot id: A0A4P9C8J4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

2041044:CPZ25 RS13115
gene id: 2041044:CPZ25_RS13115
uniprot id: A0A4P9CBN3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

2041044:CPZ25 RS13835
gene id: 2041044:CPZ25_RS13835
uniprot id: A0A4V1GM83
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MetA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

2041044:CPZ25 RS07380
gene id: 2041044:CPZ25_RS07380
uniprot id: A0A4V1GLW1
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

2041044:CPZ25 RS17580
gene id: 2041044:CPZ25_RS17580
uniprot id: A0A4P9CBR4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

2041044:CPZ25 RS14365
gene id: 2041044:CPZ25_RS14365
uniprot id: A0A4P9CCK7
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

2041044:CPZ25 RS02845
gene id: 2041044:CPZ25_RS02845
uniprot id: A0A4P9C4I4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

2041044:CPZ25 RS09070
gene id: 2041044:CPZ25_RS09070
uniprot id: A0A4P9CFT2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2041044:CPZ25 RS15100
gene id: 2041044:CPZ25_RS15100
uniprot id: A0A4P9CCM2
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

2041044:CPZ25 RS01665
gene id: 2041044:CPZ25_RS01665
uniprot id: A0A4P9C5Y6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Could methylate the ribose at the nucleotide 34 wobble position in tRNA.
messages: Cytoplasm

2041044:CPZ25 RS03495
gene id: 2041044:CPZ25_RS03495
uniprot id: A0A4P9C753
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-3 family.
messages: Cytoplasm
messages: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
messages: Monomer.

2041044:CPZ25 RS17425
gene id: 2041044:CPZ25_RS17425
uniprot id: A0A4P9CBN4
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

2041044:CPZ25 RS11845
gene id: 2041044:CPZ25_RS11845
uniprot id: A0A4P9C900
names: Similarity
messages: Belongs to the formate--tetrahydrofolate ligase family.

2041044:CPZ25 RS11820
gene id: 2041044:CPZ25_RS11820
uniprot id: A0A4P9CBA1
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

2041044:CPZ25 RS06730
gene id: 2041044:CPZ25_RS06730
uniprot id: A0A4P9C8E8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Glutamate:GABA antiporter (GGA) (TC 2.A.3.7) family.
messages: Membrane

2041044:CPZ25 RS17670
gene id: 2041044:CPZ25_RS17670
uniprot id: A0A4P9CBP9
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MobA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.
messages: Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.

2041044:CPZ25 RS19255
gene id: 2041044:CPZ25_RS19255
uniprot id: A0A4P9CF56
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

2041044:CPZ25 RS10375
gene id: 2041044:CPZ25_RS10375
uniprot id: A0A4P9C8B3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

2041044:CPZ25 RS14095
gene id: 2041044:CPZ25_RS14095
uniprot id: A0A4P9CA62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

2041044:CPZ25 RS10370
gene id: 2041044:CPZ25_RS10370
uniprot id: A0A4P9C879
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

2041044:CPZ25 RS08355
gene id: 2041044:CPZ25_RS08355
uniprot id: A0A4P9C9F8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gluconeogenesis factor family.
messages: Cytoplasm
messages: Required for morphogenesis under gluconeogenic growth conditions.