2041:Aeryth RS03180
gene id: 2041:Aeryth_RS03180
uniprot id: A0A0U4ATP9
names: Subcellular Location Annotation
messages: Membrane

2041:Aeryth RS01960
gene id: 2041:Aeryth_RS01960
uniprot id: A0A0U4C5W5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

2041:Aeryth RS03275
gene id: 2041:Aeryth_RS03275
uniprot id: A0A0U3KFK6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

2041:Aeryth RS07785
gene id: 2041:Aeryth_RS07785
uniprot id: A0A0U4B9I8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

2041:Aeryth RS01265
gene id: 2041:Aeryth_RS01265
uniprot id: A0A0U4ASJ8
names: Caution
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IcmF family.
messages: Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly.
messages: Heterodimer of an alpha and a beta chain.
messages: Homodimer.
messages: Is composed of four functional domains: the N-terminal 5'-deoxyadenosylcobalamin binding region that is homologous to the small subunit of ICM (IcmB), a middle P-loop GTPase domain (MeaI) that likely acts as a chaperone for ICM, a structured linker region involved in dimer formation, and a C-terminal part that is homologous to the large substrate-binding subunit of ICM (IcmA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2041:Aeryth RS06635
gene id: 2041:Aeryth_RS06635
uniprot id: A0A0U4B974
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

2041:Aeryth RS13265
gene id: 2041:Aeryth_RS13265
uniprot id: A0A0U4CY32
names: Subcellular Location Annotation
messages: Membrane

2041:Aeryth RS07550
gene id: 2041:Aeryth_RS07550
uniprot id: A0A0U4C0M4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

2041:Aeryth RS05405
gene id: 2041:Aeryth_RS05405
uniprot id: A0A0U4BFR2
names: Similarity
messages: Belongs to the FAD-binding monooxygenase family.

2041:Aeryth RS08030
gene id: 2041:Aeryth_RS08030
uniprot id: A0A0U4BA04
names: Similarity
messages: Belongs to the glycosyl hydrolase family 6.

2041:Aeryth RS03240
gene id: 2041:Aeryth_RS03240
uniprot id: A0A0U4CM39
names: Similarity
messages: Belongs to the isochorismate synthase family.

2041:Aeryth RS02165
gene id: 2041:Aeryth_RS02165
uniprot id: A0A0U4BDW7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

2041:Aeryth RS03570
gene id: 2041:Aeryth_RS03570
uniprot id: A0A0U4CKY3
names: Similarity
messages: Belongs to the LppX/LprAFG lipoprotein family.

2041:Aeryth RS10095
gene id: 2041:Aeryth_RS10095
uniprot id: A0A0U4DA44
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protoporphyrinogen/coproporphyrinogen oxidase family. Coproporphyrinogen III oxidase subfamily.
messages: Cytoplasm
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the oxidation of coproporphyrinogen III to coproporphyrin III.

2041:Aeryth RS04980
gene id: 2041:Aeryth_RS04980
uniprot id: A0A0U4B8C0
names: Similarity
messages: Belongs to the ABC transporter superfamily.

2041:Aeryth RS15690
gene id: 2041:Aeryth_RS15690
uniprot id: A0A0U3TKL9
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

2041:Aeryth RS13175
gene id: 2041:Aeryth_RS13175
uniprot id: A0A0U4CSG7
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

2041:Aeryth RS04535
gene id: 2041:Aeryth_RS04535
uniprot id: A0A0U4D740
names: Similarity
messages: Belongs to the UPF0065 (bug) family.

2041:Aeryth RS13640
gene id: 2041:Aeryth_RS13640
uniprot id: A0A0U4DC03
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

2041:Aeryth RS05555
gene id: 2041:Aeryth_RS05555
uniprot id: A0A0U4CNE3
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

2041:Aeryth RS00840
gene id: 2041:Aeryth_RS00840
uniprot id: A0A0U3KEB0
names: Subcellular Location Annotation
messages: Membrane

2041:Aeryth RS13160
gene id: 2041:Aeryth_RS13160
uniprot id: A0A0U4BCH8
names: Subcellular Location Annotation
messages: Cytoplasm

2041:Aeryth RS11750
gene id: 2041:Aeryth_RS11750
uniprot id: A0A0U4CBY8
names: Similarity
messages: Belongs to the UDP-galactopyranose/dTDP-fucopyranose mutase family.

2041:Aeryth RS03260
gene id: 2041:Aeryth_RS03260
uniprot id: A0A0U4ATS5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

2041:Aeryth RS09635
gene id: 2041:Aeryth_RS09635
uniprot id: A0A0U4C1X1
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2041:Aeryth RS12660
gene id: 2041:Aeryth_RS12660
uniprot id: A0A0U4C3E4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

2041:Aeryth RS09860
gene id: 2041:Aeryth_RS09860
uniprot id: A0A0U3T2H9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

2041:Aeryth RS00005
gene id: 2041:Aeryth_RS00005
uniprot id: A0A0U3SXD4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

2041:Aeryth RS00240
gene id: 2041:Aeryth_RS00240
uniprot id: A0A0U3TCH9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

2041:Aeryth RS08950
gene id: 2041:Aeryth_RS08950
uniprot id: A0A0U4BHX6
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
messages: Cytoplasm
messages: The 20S proteasome core is composed of 14 alpha and 14 beta subunits that assemble into four stacked heptameric rings, resulting in a barrel-shaped structure. The two inner rings, each composed of seven catalytic beta subunits, are sandwiched by two outer rings, each composed of seven alpha subunits. The catalytic chamber with the active sites is on the inside of the barrel. Has a gated structure, the ends of the cylinder being occluded by the N-termini of the alpha-subunits. Is capped by the proteasome-associated ATPase, ARC.
messages: The formation of the proteasomal ATPase ARC-20S proteasome complex, likely via the docking of the C-termini of ARC into the intersubunit pockets in the alpha-rings, may trigger opening of the gate for substrate entry. Interconversion between the open-gate and close-gate conformations leads to a dynamic regulation of the 20S proteasome proteolysis activity.

2041:Aeryth RS11560
gene id: 2041:Aeryth_RS11560
uniprot id: A0A0U4BBN6
names: Similarity
messages: Belongs to the acylphosphatase family.

2041:Aeryth RS07310
gene id: 2041:Aeryth_RS07310
uniprot id: A0A0U4BGW7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

2041:Aeryth RS02875
gene id: 2041:Aeryth_RS02875
uniprot id: A0A0U4CE42
names: Function
names: Similarity
names: Subunit
messages: Belongs to the serine/threonine dehydratase family.
messages: Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
messages: Homotetramer.

2041:Aeryth RS07295
gene id: 2041:Aeryth_RS07295
uniprot id: A0A0U4C9H8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

2041:Aeryth RS17110
gene id: 2041:Aeryth_RS17110
uniprot id: A0A0U4CUN4
names: Similarity
messages: Belongs to the shaker potassium channel beta subunit family.

2041:Aeryth RS09425
gene id: 2041:Aeryth_RS09425
uniprot id: A0A0U3T2L9
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

2041:Aeryth RS02725
gene id: 2041:Aeryth_RS02725
uniprot id: A0A0U4B6L6
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

2041:Aeryth RS03315
gene id: 2041:Aeryth_RS03315
uniprot id: A0A0U4C6K5
names: Subcellular Location Annotation
messages: Membrane

2041:Aeryth RS08265
gene id: 2041:Aeryth_RS08265
uniprot id: A0A0U4C144
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Cytoplasm
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the insertion of ferrous iron into coproporphyrin III to form Fe-coproporphyrin III.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2041:Aeryth RS10725
gene id: 2041:Aeryth_RS10725
uniprot id: A0A0U4BBI3
names: Caution
names: PTM
names: Subcellular Location Annotation
names: Subunit
messages: Binds 2 heme c groups covalently per subunit.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The cytochrome bc1 complex is composed of a cytochrome b (QcrB), the Rieske iron-sulfur protein (QcrA) and a diheme cytochrome c (QcrC) subunit.

2041:Aeryth RS09370
gene id: 2041:Aeryth_RS09370
uniprot id: A0A0U4CVZ0
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
messages: Membrane

2041:Aeryth RS04310
gene id: 2041:Aeryth_RS04310
uniprot id: A0A0U3SZJ6
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

2041:Aeryth RS10055
gene id: 2041:Aeryth_RS10055
uniprot id: A0A0U3T2L4
names: Function
messages: Catalyzes the reduction of sulfite to sulfide, a step in the biosynthesis of sulfur-containing amino acids and cofactors.

2041:Aeryth RS06590
gene id: 2041:Aeryth_RS06590
uniprot id: A0A0U4C868
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

2041:Aeryth RS14735
gene id: 2041:Aeryth_RS14735
uniprot id: A0A0U3T582
names: Subcellular Location Annotation
messages: Membrane

2041:Aeryth RS07345
gene id: 2041:Aeryth_RS07345
uniprot id: A0A0U3T1C9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein S19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein S19.

2041:Aeryth RS04820
gene id: 2041:Aeryth_RS04820
uniprot id: A0A0U4CLM2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

2041:Aeryth RS06025
gene id: 2041:Aeryth_RS06025
uniprot id: A0A0U4BZK7
names: Subcellular Location Annotation
messages: Membrane

2041:Aeryth RS00220
gene id: 2041:Aeryth_RS00220
uniprot id: A0A0U3KDU4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

2041:Aeryth RS13345
gene id: 2041:Aeryth_RS13345
uniprot id: A0A0U3T4H0
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

2041:Aeryth RS06765
gene id: 2041:Aeryth_RS06765
uniprot id: A0A0U4CUE3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NucS endonuclease family.
messages: Cleaves both 3' and 5' ssDNA extremities of branched DNA structures.
messages: Cytoplasm

2041:Aeryth RS09780
gene id: 2041:Aeryth_RS09780
uniprot id: A0A0U3T2G3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.

2041:Aeryth RS08420
gene id: 2041:Aeryth_RS08420
uniprot id: A0A0U4CPY7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-3 family.
messages: Cytoplasm
messages: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
messages: Monomer.

2041:Aeryth RS10555
gene id: 2041:Aeryth_RS10555
uniprot id: A0A0U4BBF3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2041:Aeryth RS11340
gene id: 2041:Aeryth_RS11340
uniprot id: A0A0U4CIP3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

2041:Aeryth RS07325
gene id: 2041:Aeryth_RS07325
uniprot id: A0A0U4B9K0
names: Similarity
messages: Belongs to the ArsC family.

2041:Aeryth RS11730
gene id: 2041:Aeryth_RS11730
uniprot id: A0A0U3T3H8
names: Subcellular Location Annotation
messages: Membrane

2041:Aeryth RS00805
gene id: 2041:Aeryth_RS00805
uniprot id: A0A0U4CR49
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

2041:Aeryth RS02830
gene id: 2041:Aeryth_RS02830
uniprot id: A0A0U4CS51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

2041:Aeryth RS02810
gene id: 2041:Aeryth_RS02810
uniprot id: A0A0U4B6N6
names: Subcellular Location Annotation
messages: Membrane

2041:Aeryth RS16965
gene id: 2041:Aeryth_RS16965
uniprot id: A0A0U4C5U6
names: Similarity
messages: Belongs to the Dps family.

2041:Aeryth RS11365
gene id: 2041:Aeryth_RS11365
uniprot id: A0A0U4BBK2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

2041:Aeryth RS02835
gene id: 2041:Aeryth_RS02835
uniprot id: A0A0U4C6Y5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2041:Aeryth RS07245
gene id: 2041:Aeryth_RS07245
uniprot id: A0A0U4CGF1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

2041:Aeryth RS11720
gene id: 2041:Aeryth_RS11720
uniprot id: A0A0U3T3W5
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

2041:Aeryth RS07930
gene id: 2041:Aeryth_RS07930
uniprot id: A0A0U3KI84
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

2041:Aeryth RS05570
gene id: 2041:Aeryth_RS05570
uniprot id: A0A0U4BZC6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

2041:Aeryth RS01520
gene id: 2041:Aeryth_RS01520
uniprot id: A0A0U4CL84
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

2041:Aeryth RS09460
gene id: 2041:Aeryth_RS09460
uniprot id: A0A0U4C1T1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

2041:Aeryth RS07845
gene id: 2041:Aeryth_RS07845
uniprot id: A0A0U4CGU9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

2041:Aeryth RS13655
gene id: 2041:Aeryth_RS13655
uniprot id: A0A0U4CJY0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

2041:Aeryth RS09865
gene id: 2041:Aeryth_RS09865
uniprot id: A0A0U4CAF7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvB family.
messages: Forms a complex with RuvA.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.

2041:Aeryth RS06455
gene id: 2041:Aeryth_RS06455
uniprot id: A0A0U4D848
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

2041:Aeryth RS07410
gene id: 2041:Aeryth_RS07410
uniprot id: A0A0U4B9L8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

2041:Aeryth RS09785
gene id: 2041:Aeryth_RS09785
uniprot id: A0A0U4CAE1
names: Similarity
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Homodimer.

2041:Aeryth RS12420
gene id: 2041:Aeryth_RS12420
uniprot id: A0A0U4BCJ0
names: Similarity
messages: Belongs to the UDPGP type 1 family.

2041:Aeryth RS05845
gene id: 2041:Aeryth_RS05845
uniprot id: A0A0U4D7T7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

2041:Aeryth RS12485
gene id: 2041:Aeryth_RS12485
uniprot id: A0A0U4CC96
names: Similarity
messages: Belongs to the malate synthase family.

2041:Aeryth RS13555
gene id: 2041:Aeryth_RS13555
uniprot id: A0A0U4BKH1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

2041:Aeryth RS03575
gene id: 2041:Aeryth_RS03575
uniprot id: A0A0U3TE67
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

2041:Aeryth RS12545
gene id: 2041:Aeryth_RS12545
uniprot id: A0A0U4BC72
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DtxR/MntR family.
messages: Cytoplasm
messages: Homodimer.

2041:Aeryth RS02350
gene id: 2041:Aeryth_RS02350
uniprot id: A0A0U4CDV5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tryptophan 2,3-dioxygenase family.
messages: Binds 1 heme group per subunit.
messages: Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L-tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety.
messages: Homotetramer.

2041:Aeryth RS12570
gene id: 2041:Aeryth_RS12570
uniprot id: A0A0U4CCA4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2041:Aeryth RS14130
gene id: 2041:Aeryth_RS14130
uniprot id: A0A0U3TJL2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

2041:Aeryth RS11985
gene id: 2041:Aeryth_RS11985
uniprot id: A0A0U4CIZ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

2041:Aeryth RS07710
gene id: 2041:Aeryth_RS07710
uniprot id: A0A0U4CPN1
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

2041:Aeryth RS11895
gene id: 2041:Aeryth_RS11895
uniprot id: A0A0U3TIG3
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the peroxidase family. Peroxidase/catalase subfamily.
messages: Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.
messages: Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2041:Aeryth RS13610
gene id: 2041:Aeryth_RS13610
uniprot id: A0A0U4CSM4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

2041:Aeryth RS12690
gene id: 2041:Aeryth_RS12690
uniprot id: A0A0U4CJH8
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

2041:Aeryth RS05610
gene id: 2041:Aeryth_RS05610
uniprot id: A0A0U4CM49
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Heptamer of 7 subunits arranged in a ring.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

2041:Aeryth RS10550
gene id: 2041:Aeryth_RS10550
uniprot id: A0A0U3KJW4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

2041:Aeryth RS13470
gene id: 2041:Aeryth_RS13470
uniprot id: A0A0U4DBX3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2041:Aeryth RS13510
gene id: 2041:Aeryth_RS13510
uniprot id: A0A0U4BCN4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

2041:Aeryth RS09450
gene id: 2041:Aeryth_RS09450
uniprot id: A0A0U4CW07
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

2041:Aeryth RS10840
gene id: 2041:Aeryth_RS10840
uniprot id: A0A0U3T309
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

2041:Aeryth RS09230
gene id: 2041:Aeryth_RS09230
uniprot id: A0A0U3KJ59
names: Similarity
messages: Belongs to the UPF0098 family.

2041:Aeryth RS10635
gene id: 2041:Aeryth_RS10635
uniprot id: A0A0U4BBH1
names: Similarity
messages: Belongs to the class-II DAHP synthase family.

2041:Aeryth RS09380
gene id: 2041:Aeryth_RS09380
uniprot id: A0A0U4C1S2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 2 subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

2041:Aeryth RS10220
gene id: 2041:Aeryth_RS10220
uniprot id: A0A0U4BAY7
names: Similarity
messages: Belongs to the peptidase M18 family.

2041:Aeryth RS03905
gene id: 2041:Aeryth_RS03905
uniprot id: A0A0U4D6R9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

2041:Aeryth RS06620
gene id: 2041:Aeryth_RS06620
uniprot id: A0A0U4BGH5
names: Subcellular Location Annotation
messages: Membrane

2041:Aeryth RS03645
gene id: 2041:Aeryth_RS03645
uniprot id: A0A0U4D6M4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

2041:Aeryth RS00360
gene id: 2041:Aeryth_RS00360
uniprot id: A0A0U4CKN4
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

2041:Aeryth RS10770
gene id: 2041:Aeryth_RS10770
uniprot id: A0A0U4CWR0
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

2041:Aeryth RS03395
gene id: 2041:Aeryth_RS03395
uniprot id: A0A0U3SZ89
names: Function
names: Similarity
messages: Belongs to the AlaDH/PNT family.
messages: Catalyzes the reversible reductive amination of pyruvate to L-alanine.

2041:Aeryth RS07265
gene id: 2041:Aeryth_RS07265
uniprot id: A0A0U4B988
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

2041:Aeryth RS08395
gene id: 2041:Aeryth_RS08395
uniprot id: A0A0U3T206
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA-PH family.
messages: Cytoplasm

2041:Aeryth RS13435
gene id: 2041:Aeryth_RS13435
uniprot id: A0A0U4CCL7
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

2041:Aeryth RS07455
gene id: 2041:Aeryth_RS07455
uniprot id: A0A0U4CPI2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

2041:Aeryth RS14695
gene id: 2041:Aeryth_RS14695
uniprot id: A0A0U4DCK5
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

2041:Aeryth RS00750
gene id: 2041:Aeryth_RS00750
uniprot id: A0A0U4CD32
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
messages: Catalyzes the reversible phosphorylation of S-methyl-5'-thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.
messages: Homohexamer. Dimer of a homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2041:Aeryth RS10320
gene id: 2041:Aeryth_RS10320
uniprot id: A0A0U3T2R2
names: Similarity
names: Subunit
messages: Belongs to the pyruvate kinase family.
messages: Homotetramer.

2041:Aeryth RS03535
gene id: 2041:Aeryth_RS03535
uniprot id: A0A0U4ATY0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

2041:Aeryth RS08495
gene id: 2041:Aeryth_RS08495
uniprot id: A0A0U4C9Q2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

2041:Aeryth RS02885
gene id: 2041:Aeryth_RS02885
uniprot id: A0A0U3TDU5
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

2041:Aeryth RS04520
gene id: 2041:Aeryth_RS04520
uniprot id: A0A0U4BYT4
names: Subcellular Location Annotation
messages: Membrane

2041:Aeryth RS11495
gene id: 2041:Aeryth_RS11495
uniprot id: A0A0U4CBT7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homotetramer.

2041:Aeryth RS12745
gene id: 2041:Aeryth_RS12745
uniprot id: A0A0U4CCC5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

2041:Aeryth RS06975
gene id: 2041:Aeryth_RS06975
uniprot id: A0A0U4B9D9
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

2041:Aeryth RS08460
gene id: 2041:Aeryth_RS08460
uniprot id: A0A0U4BAA8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 2 subfamily.
messages: Cytoplasm
messages: Homotetramer.

2041:Aeryth RS14025
gene id: 2041:Aeryth_RS14025
uniprot id: A0A0U4CK43
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.
messages: Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2041:Aeryth RS03200
gene id: 2041:Aeryth_RS03200
uniprot id: A0A0U4B7D4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MenA family. Type 1 subfamily.
messages: Cell membrane
messages: Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

2041:Aeryth RS00010
gene id: 2041:Aeryth_RS00010
uniprot id: A0A0U4C4X5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

2041:Aeryth RS04920
gene id: 2041:Aeryth_RS04920
uniprot id: A0A0U3T010
names: Similarity
messages: Belongs to the adenylyl cyclase class-3 family.

2041:Aeryth RS13150
gene id: 2041:Aeryth_RS13150
uniprot id: A0A0U3TJ41
names: Subcellular Location Annotation
messages: Membrane

2041:Aeryth RS03520
gene id: 2041:Aeryth_RS03520
uniprot id: A0A0U4CSL9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

2041:Aeryth RS14855
gene id: 2041:Aeryth_RS14855
uniprot id: A0A0U4DCQ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

2041:Aeryth RS14240
gene id: 2041:Aeryth_RS14240
uniprot id: A0A0U4CSY6
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
messages: Belongs to the nitrobindin family.
messages: Binds 1 heme b group per subunit, that coordinates a highly solvent-exposed Fe(III) atom.
messages: Forms a 10-stranded antiparallel beta-barrel structure able to accommodate a hydrophobic ligand in its interior. In fact, this fold hosts the heme group, which is located in a wide surface cleft.
messages: Heme-binding protein able to scavenge peroxynitrite and to protect free L-tyrosine against peroxynitrite-mediated nitration, by acting as a peroxynitrite isomerase that converts peroxynitrite to nitrate. Therefore, this protein likely plays a role in peroxynitrite sensing and in the detoxification of reactive nitrogen and oxygen species (RNS and ROS, respectively). Is able to bind nitric oxide (NO) in vitro, but may act as a sensor of peroxynitrite levels in vivo.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2041:Aeryth RS13400
gene id: 2041:Aeryth_RS13400
uniprot id: A0A0U4CJU4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaD and TsaB. TsaE seems to play an indirect role in the t(6)A biosynthesis pathway, possibly in regulating the core enzymatic function of TsaD.

2041:Aeryth RS10410
gene id: 2041:Aeryth_RS10410
uniprot id: A0A0U3T2T0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

2041:Aeryth RS08590
gene id: 2041:Aeryth_RS08590
uniprot id: A0A0U4CVK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

2041:Aeryth RS11050
gene id: 2041:Aeryth_RS11050
uniprot id: A0A0U3KK57
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

2041:Aeryth RS11175
gene id: 2041:Aeryth_RS11175
uniprot id: A0A0U4BBH0
names: Subcellular Location Annotation
messages: Membrane

2041:Aeryth RS12345
gene id: 2041:Aeryth_RS12345
uniprot id: A0A0U4BC38
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2041:Aeryth RS11155
gene id: 2041:Aeryth_RS11155
uniprot id: A0A0U4CIL7
names: Similarity
messages: Belongs to the UPF0045 family.

2041:Aeryth RS05625
gene id: 2041:Aeryth_RS05625
uniprot id: A0A0U4B896
names: Subcellular Location Annotation
messages: Membrane

2041:Aeryth RS04150
gene id: 2041:Aeryth_RS04150
uniprot id: A0A0U4BYL5
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

2041:Aeryth RS08215
gene id: 2041:Aeryth_RS08215
uniprot id: A0A0U3TGI2
names: Similarity
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.

2041:Aeryth RS00525
gene id: 2041:Aeryth_RS00525
uniprot id: A0A0U3SXM7
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

2041:Aeryth RS08960
gene id: 2041:Aeryth_RS08960
uniprot id: A0A0U3KIZ8
names: Caution
names: Domain
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic ubiquitin-like protein family.
messages: Is modified by deamidation of its C-terminal glutamine to glutamate by the deamidase Dop, a prerequisite to the subsequent pupylation process.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation.
messages: Strongly interacts with the proteasome-associated ATPase ARC through a hydrophobic interface; the interacting region of Pup lies in its C-terminal half. There is one Pup binding site per ARC hexamer ring.
messages: The N-terminal unstructured half of Pup provides a signal required to initiate unfolding and degradation by the proteasome but is not needed for pupylation, while the C-terminal helical half of Pup interacts with ARC to target proteins to the proteasome.

2041:Aeryth RS09360
gene id: 2041:Aeryth_RS09360
uniprot id: A0A0U4CA62
names: Subcellular Location Annotation
messages: Membrane

2041:Aeryth RS05115
gene id: 2041:Aeryth_RS05115
uniprot id: A0A0U4C8G4
names: Similarity
messages: Belongs to the PspA/IM30 family.

2041:Aeryth RS08485
gene id: 2041:Aeryth_RS08485
uniprot id: A0A0U4BA06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

2041:Aeryth RS10560
gene id: 2041:Aeryth_RS10560
uniprot id: A0A0U4CIB3
names: Subcellular Location Annotation
messages: Membrane

2041:Aeryth RS04390
gene id: 2041:Aeryth_RS04390
uniprot id: A0A0U4B7K8
names: Function
names: Similarity
messages: ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.
messages: Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.

2041:Aeryth RS15360
gene id: 2041:Aeryth_RS15360
uniprot id: A0A0U4CTK8
names: Function
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

2041:Aeryth RS11970
gene id: 2041:Aeryth_RS11970
uniprot id: A0A0U3KKS3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

2041:Aeryth RS07390
gene id: 2041:Aeryth_RS07390
uniprot id: A0A0U4BGZ3
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

2041:Aeryth RS03265
gene id: 2041:Aeryth_RS03265
uniprot id: A0A0U4BEJ1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

2041:Aeryth RS00275
gene id: 2041:Aeryth_RS00275
uniprot id: A0A0U4C5Q5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Atypical ATP-dependent clade 'X' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homodimer.

2041:Aeryth RS11950
gene id: 2041:Aeryth_RS11950
uniprot id: A0A0U4C327
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein L14 (rplN).

2041:Aeryth RS16690
gene id: 2041:Aeryth_RS16690
uniprot id: A0A0U4CEK2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

2041:Aeryth RS02160
gene id: 2041:Aeryth_RS02160
uniprot id: A0A0U4ASZ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

2041:Aeryth RS16180
gene id: 2041:Aeryth_RS16180
uniprot id: A0A0U4B0S1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

2041:Aeryth RS07195
gene id: 2041:Aeryth_RS07195
uniprot id: A0A0U4C8V4
names: Similarity
messages: Belongs to the Fur family.

2041:Aeryth RS12460
gene id: 2041:Aeryth_RS12460
uniprot id: A0A0U3T409
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

2041:Aeryth RS03960
gene id: 2041:Aeryth_RS03960
uniprot id: A0A0U4CMH6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the ABC transporter complex (TC 3.A.1.6.1) involved in sulfate/thiosulfate import.
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

2041:Aeryth RS03095
gene id: 2041:Aeryth_RS03095
uniprot id: A0A0U4ATL0
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

2041:Aeryth RS06715
gene id: 2041:Aeryth_RS06715
uniprot id: A0A0U3KHG7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

2041:Aeryth RS01895
gene id: 2041:Aeryth_RS01895
uniprot id: A0A0U4BDS4
names: Similarity
messages: Belongs to the CsoR family.

2041:Aeryth RS11170
gene id: 2041:Aeryth_RS11170
uniprot id: A0A0U3T3J7
names: Function
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

2041:Aeryth RS10540
gene id: 2041:Aeryth_RS10540
uniprot id: A0A0U4BIS2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

2041:Aeryth RS07450
gene id: 2041:Aeryth_RS07450
uniprot id: A0A0U4C900
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

2041:Aeryth RS00615
gene id: 2041:Aeryth_RS00615
uniprot id: A0A0U4CKS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2041:Aeryth RS08370
gene id: 2041:Aeryth_RS08370
uniprot id: A0A0U3KIN0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

2041:Aeryth RS08135
gene id: 2041:Aeryth_RS08135
uniprot id: A0A0U3T1U0
names: Similarity
messages: Belongs to the peptidase S9A family.

2041:Aeryth RS07495
gene id: 2041:Aeryth_RS07495
uniprot id: A0A0U4B9P3
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

2041:Aeryth RS00910
gene id: 2041:Aeryth_RS00910
uniprot id: A0A0U4BDB0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

2041:Aeryth RS04930
gene id: 2041:Aeryth_RS04930
uniprot id: A0A0U3SZW8
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

2041:Aeryth RS16295
gene id: 2041:Aeryth_RS16295
uniprot id: A0A0U4CSN4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2041:Aeryth RS00710
gene id: 2041:Aeryth_RS00710
uniprot id: A0A0U4C5Y2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

2041:Aeryth RS09435
gene id: 2041:Aeryth_RS09435
uniprot id: A0A0U3T2A0
names: Function
names: Similarity
messages: Belongs to the WhiA family.
messages: Involved in cell division and chromosome segregation.

2041:Aeryth RS06980
gene id: 2041:Aeryth_RS06980
uniprot id: A0A0U4CGA4
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

2041:Aeryth RS01540
gene id: 2041:Aeryth_RS01540
uniprot id: A0A0U4BX48
names: Similarity
messages: Belongs to the peptidase S1 family.

2041:Aeryth RS10435
gene id: 2041:Aeryth_RS10435
uniprot id: A0A0U4CBA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

2041:Aeryth RS12590
gene id: 2041:Aeryth_RS12590
uniprot id: A0A0U4DBG0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: Homotrimer.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. Cleaves guanosine, inosine, 2'-deoxyguanosine and 2'-deoxyinosine.

2041:Aeryth RS08390
gene id: 2041:Aeryth_RS08390
uniprot id: A0A0U3TGK6
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

2041:Aeryth RS09005
gene id: 2041:Aeryth_RS09005
uniprot id: A0A0U4C9Z8
names: Domain
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
messages: Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.

2041:Aeryth RS06985
gene id: 2041:Aeryth_RS06985
uniprot id: A0A0U4CMW9
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

2041:Aeryth RS14965
gene id: 2041:Aeryth_RS14965
uniprot id: A0A0U4CDJ3
names: Similarity
messages: Belongs to the WXG100 family.

2041:Aeryth RS13565
gene id: 2041:Aeryth_RS13565
uniprot id: A0A0U3KLV1
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

2041:Aeryth RS13700
gene id: 2041:Aeryth_RS13700
uniprot id: A0A0U4CCS5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

2041:Aeryth RS07260
gene id: 2041:Aeryth_RS07260
uniprot id: A0A0U3T1A0
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

2041:Aeryth RS01920
gene id: 2041:Aeryth_RS01920
uniprot id: A0A0U4CDL1
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

2041:Aeryth RS07895
gene id: 2041:Aeryth_RS07895
uniprot id: A0A0U4CV29
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2041:Aeryth RS14185
gene id: 2041:Aeryth_RS14185
uniprot id: A0A0U4DCB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BCCT transporter (TC 2.A.15) family.
messages: Membrane

2041:Aeryth RS12045
gene id: 2041:Aeryth_RS12045
uniprot id: A0A0U4C341
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2041:Aeryth RS13930
gene id: 2041:Aeryth_RS13930
uniprot id: A0A0U4CRH0
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

2041:Aeryth RS03865
gene id: 2041:Aeryth_RS03865
uniprot id: A0A0U4CMG2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

2041:Aeryth RS07360
gene id: 2041:Aeryth_RS07360
uniprot id: A0A0U4C8Y7
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

2041:Aeryth RS08140
gene id: 2041:Aeryth_RS08140
uniprot id: A0A0U4B9Q9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

2041:Aeryth RS12810
gene id: 2041:Aeryth_RS12810
uniprot id: A0A0U4CCB0
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

2041:Aeryth RS12340
gene id: 2041:Aeryth_RS12340
uniprot id: A0A0U3T471
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

2041:Aeryth RS10980
gene id: 2041:Aeryth_RS10980
uniprot id: A0A0U4CII4
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

2041:Aeryth RS09420
gene id: 2041:Aeryth_RS09420
uniprot id: A0A0U3TH35
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

2041:Aeryth RS11700
gene id: 2041:Aeryth_RS11700
uniprot id: A0A0U4BC36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

2041:Aeryth RS10140
gene id: 2041:Aeryth_RS10140
uniprot id: A0A0U4CAK3
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

2041:Aeryth RS00800
gene id: 2041:Aeryth_RS00800
uniprot id: A0A0U4CKV9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pseudouridine-5'-phosphate glycosidase family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the reversible cleavage of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway.
messages: Homotrimer.

2041:Aeryth RS07555
gene id: 2041:Aeryth_RS07555
uniprot id: A0A0U4AW07
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

2041:Aeryth RS06185
gene id: 2041:Aeryth_RS06185
uniprot id: A0A0U4CMG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0719 family.
messages: Membrane

2041:Aeryth RS16160
gene id: 2041:Aeryth_RS16160
uniprot id: A0A0U4CZU9
names: Similarity
names: Subunit
messages: Belongs to the aminoglycoside phosphotransferase family.
messages: Monomer.

2041:Aeryth RS11115
gene id: 2041:Aeryth_RS11115
uniprot id: A0A0U4CBK0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GDT1 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

2041:Aeryth RS00230
gene id: 2041:Aeryth_RS00230
uniprot id: A0A0U4CCS8
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

2041:Aeryth RS02095
gene id: 2041:Aeryth_RS02095
uniprot id: A0A0U4CDN0
names: Subcellular Location Annotation
messages: Membrane

2041:Aeryth RS08385
gene id: 2041:Aeryth_RS08385
uniprot id: A0A0U4CNQ1
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

2041:Aeryth RS02205
gene id: 2041:Aeryth_RS02205
uniprot id: A0A0U3SYJ7
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

2041:Aeryth RS09605
gene id: 2041:Aeryth_RS09605
uniprot id: A0A0U4BAM9
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2041:Aeryth RS00590
gene id: 2041:Aeryth_RS00590
uniprot id: A0A0U3TCN2
names: Similarity
messages: Belongs to the xanthine dehydrogenase family.

2041:Aeryth RS11660
gene id: 2041:Aeryth_RS11660
uniprot id: A0A0U4CRS4
names: Subcellular Location Annotation
messages: Membrane

2041:Aeryth RS06660
gene id: 2041:Aeryth_RS06660
uniprot id: A0A0U4B8U0
names: Caution
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

2041:Aeryth RS14510
gene id: 2041:Aeryth_RS14510
uniprot id: A0A0U4CD76
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

2041:Aeryth RS03920
gene id: 2041:Aeryth_RS03920
uniprot id: A0A0U4CEL8
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 2 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

2041:Aeryth RS00555
gene id: 2041:Aeryth_RS00555
uniprot id: A0A0U4AS54
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.
messages: Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU).
messages: Homotetramer.

2041:Aeryth RS05050
gene id: 2041:Aeryth_RS05050
uniprot id: A0A0U4BFI7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

2041:Aeryth RS18500
gene id: 2041:Aeryth_RS18500
uniprot id: A0A0U4CMW3
names: Function
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Involved in the hydrocarbon hydroxylating system, which transfers electrons from NADH to rubredoxin reductase and then through rubredoxin to alkane 1 monooxygenase.

2041:Aeryth RS16505
gene id: 2041:Aeryth_RS16505
uniprot id: A0A0U3T681
names: Similarity
messages: Belongs to the UPF0749 family.

2041:Aeryth RS17015
gene id: 2041:Aeryth_RS17015
uniprot id: A0A0U4BEU5
names: Similarity
messages: Belongs to the Rv1128c/1148c/1588c/1702c/1945/3466 family.

2041:Aeryth RS08050
gene id: 2041:Aeryth_RS08050
uniprot id: A0A0U3T1R9
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

2041:Aeryth RS08100
gene id: 2041:Aeryth_RS08100
uniprot id: A0A0U4BHF1
names: Subcellular Location Annotation
messages: Cytoplasm

2041:Aeryth RS15555
gene id: 2041:Aeryth_RS15555
uniprot id: A0A0U4C4Y1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mediates influx of magnesium ions.
messages: Membrane

2041:Aeryth RS03365
gene id: 2041:Aeryth_RS03365
uniprot id: A0A0U3KFL6
names: Similarity
messages: Belongs to the AHA1 family.

2041:Aeryth RS05495
gene id: 2041:Aeryth_RS05495
uniprot id: A0A0U4BFU1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ClpS family.
messages: Binds to the N-terminal domain of the chaperone ClpA.
messages: Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.

2041:Aeryth RS08955
gene id: 2041:Aeryth_RS08955
uniprot id: A0A0U4D9I0
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
messages: Cytoplasm
messages: The 20S proteasome core is composed of 14 alpha and 14 beta subunits that assemble into four stacked heptameric rings, resulting in a barrel-shaped structure. The two inner rings, each composed of seven catalytic beta subunits, are sandwiched by two outer rings, each composed of seven alpha subunits. The catalytic chamber with the active sites is on the inside of the barrel. Has a gated structure, the ends of the cylinder being occluded by the N-termini of the alpha-subunits. Is capped by the proteasome-associated ATPase, ARC.
messages: The formation of the proteasomal ATPase ARC-20S proteasome complex, likely via the docking of the C-termini of ARC into the intersubunit pockets in the alpha-rings, may trigger opening of the gate for substrate entry. Interconversion between the open-gate and close-gate conformations leads to a dynamic regulation of the 20S proteasome proteolysis activity.

2041:Aeryth RS14790
gene id: 2041:Aeryth_RS14790
uniprot id: A0A0U4CRZ0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

2041:Aeryth RS03430
gene id: 2041:Aeryth_RS03430
uniprot id: A0A0U4BY75
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2041:Aeryth RS09880
gene id: 2041:Aeryth_RS09880
uniprot id: A0A0U4CB03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

2041:Aeryth RS09155
gene id: 2041:Aeryth_RS09155
uniprot id: A0A0U4CHJ6
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

2041:Aeryth RS17160
gene id: 2041:Aeryth_RS17160
uniprot id: A0A0U4CLT2
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

2041:Aeryth RS00080
gene id: 2041:Aeryth_RS00080
uniprot id: A0A0U3TCF0
names: Similarity
messages: Belongs to the class-D beta-lactamase family.

2041:Aeryth RS07605
gene id: 2041:Aeryth_RS07605
uniprot id: A0A0U3TG65
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

2041:Aeryth RS09875
gene id: 2041:Aeryth_RS09875
uniprot id: A0A0U4CW82
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RuvC family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.

2041:Aeryth RS16820
gene id: 2041:Aeryth_RS16820
uniprot id: A0A0U3KP28
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sirtuin family. Class II subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form.

2041:Aeryth RS11345
gene id: 2041:Aeryth_RS11345
uniprot id: A0A0U4CQA3
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

2041:Aeryth RS10525
gene id: 2041:Aeryth_RS10525
uniprot id: A0A0U4CBB7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SepF family.
messages: Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
messages: Cytoplasm
messages: Homodimer. Interacts with FtsZ.

2041:Aeryth RS02690
gene id: 2041:Aeryth_RS02690
uniprot id: A0A0U3KF96
names: Similarity
messages: Belongs to the cysteine dioxygenase family.

2041:Aeryth RS07340
gene id: 2041:Aeryth_RS07340
uniprot id: A0A0U3TG27
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: A probable RNA-binding protein.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm

2041:Aeryth RS09355
gene id: 2041:Aeryth_RS09355
uniprot id: A0A0U3T288
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

2041:Aeryth RS04995
gene id: 2041:Aeryth_RS04995
uniprot id: A0A0U3TEZ7
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

2041:Aeryth RS07935
gene id: 2041:Aeryth_RS07935
uniprot id: A0A0U4B9Y3
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

2041:Aeryth RS13645
gene id: 2041:Aeryth_RS13645
uniprot id: A0A0U3KLW7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

2041:Aeryth RS12995
gene id: 2041:Aeryth_RS12995
uniprot id: A0A0U4CSD2
names: Similarity
messages: Belongs to the extradiol ring-cleavage dioxygenase family.

2041:Aeryth RS13770
gene id: 2041:Aeryth_RS13770
uniprot id: A0A0U4CCR8
names: Similarity
messages: Belongs to the homogentisate dioxygenase family.

2041:Aeryth RS13590
gene id: 2041:Aeryth_RS13590
uniprot id: A0A0U3T4V2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

2041:Aeryth RS09415
gene id: 2041:Aeryth_RS09415
uniprot id: A0A0U4CP66
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

2041:Aeryth RS04925
gene id: 2041:Aeryth_RS04925
uniprot id: A0A0U4B7V5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2041:Aeryth RS07685
gene id: 2041:Aeryth_RS07685
uniprot id: A0A0U3TG78
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

2041:Aeryth RS09160
gene id: 2041:Aeryth_RS09160
uniprot id: A0A0U4CP21
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

2041:Aeryth RS09375
gene id: 2041:Aeryth_RS09375
uniprot id: A0A0U4CAR9
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Homodimer.

2041:Aeryth RS14590
gene id: 2041:Aeryth_RS14590
uniprot id: A0A0U4CDA2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobD/CbiB family.
messages: Cell membrane
messages: Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
messages: Membrane

2041:Aeryth RS03930
gene id: 2041:Aeryth_RS03930
uniprot id: A0A0U3TEE6
names: Cofactor
names: Similarity
messages: Belongs to the monomeric-type IDH family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

2041:Aeryth RS07570
gene id: 2041:Aeryth_RS07570
uniprot id: A0A0U3KI15
names: Subcellular Location Annotation
messages: Membrane

2041:Aeryth RS15735
gene id: 2041:Aeryth_RS15735
uniprot id: A0A0U4CDU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2041:Aeryth RS15185
gene id: 2041:Aeryth_RS15185
uniprot id: A0A0U4CZ99
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

2041:Aeryth RS11325
gene id: 2041:Aeryth_RS11325
uniprot id: A0A0U4DAT0
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

2041:Aeryth RS17550
gene id: 2041:Aeryth_RS17550
uniprot id: A0A0U4B6G8
names: Similarity
messages: Belongs to the EfeM/EfeO family.

2041:Aeryth RS11255
gene id: 2041:Aeryth_RS11255
uniprot id: A0A0U4CIM8
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

2041:Aeryth RS10895
gene id: 2041:Aeryth_RS10895
uniprot id: A0A0U4CIG3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glutamine synthetase family.
messages: Cytoplasm
messages: Oligomer of 12 subunits arranged in the form of two hexagons.

2041:Aeryth RS08865
gene id: 2041:Aeryth_RS08865
uniprot id: A0A0U4D9G8
names: Subcellular Location Annotation
messages: Membrane

2041:Aeryth RS05240
gene id: 2041:Aeryth_RS05240
uniprot id: A0A0U4CF94
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF2.
messages: Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.

2041:Aeryth RS04230
gene id: 2041:Aeryth_RS04230
uniprot id: A0A0U4CT11
names: Subcellular Location Annotation
messages: Cytoplasm

2041:Aeryth RS03295
gene id: 2041:Aeryth_RS03295
uniprot id: A0A0U3TE17
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

2041:Aeryth RS13545
gene id: 2041:Aeryth_RS13545
uniprot id: A0A0U4C3W1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

2041:Aeryth RS08320
gene id: 2041:Aeryth_RS08320
uniprot id: A0A0U4B9W2
names: Subcellular Location Annotation
messages: Membrane

2041:Aeryth RS11510
gene id: 2041:Aeryth_RS11510
uniprot id: A0A0U4BJA2
names: Subcellular Location Annotation
messages: Membrane

2041:Aeryth RS02910
gene id: 2041:Aeryth_RS02910
uniprot id: A0A0U4CLY6
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

2041:Aeryth RS04035
gene id: 2041:Aeryth_RS04035
uniprot id: A0A0U4C6X4
names: Cofactor
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.

2041:Aeryth RS15915
gene id: 2041:Aeryth_RS15915
uniprot id: A0A0U4B0M4
names: Similarity
messages: Belongs to the glycosyltransferase 28 family.

2041:Aeryth RS05130
gene id: 2041:Aeryth_RS05130
uniprot id: A0A0U4BFK6
names: Subcellular Location Annotation
messages: Membrane

2041:Aeryth RS07730
gene id: 2041:Aeryth_RS07730
uniprot id: A0A0U4AW37
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

2041:Aeryth RS09725
gene id: 2041:Aeryth_RS09725
uniprot id: A0A0U4BIC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

2041:Aeryth RS08870
gene id: 2041:Aeryth_RS08870
uniprot id: A0A0U3KIX4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase-binding protein RbpA family.
messages: Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters.
messages: Forms a complex with the RNAP catalytic core and with free principal sigma factors.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2041:Aeryth RS01000
gene id: 2041:Aeryth_RS01000
uniprot id: A0A0U4D588
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

2041:Aeryth RS04675
gene id: 2041:Aeryth_RS04675
uniprot id: A0A0U4C786
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acid desaturase type 1 family. AlkB subfamily.
messages: Cell inner membrane
messages: Membrane

2041:Aeryth RS15035
gene id: 2041:Aeryth_RS15035
uniprot id: A0A0U3KMM3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

2041:Aeryth RS12445
gene id: 2041:Aeryth_RS12445
uniprot id: A0A0U3TIQ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

2041:Aeryth RS09510
gene id: 2041:Aeryth_RS09510
uniprot id: A0A0U3TH47
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

2041:Aeryth RS05895
gene id: 2041:Aeryth_RS05895
uniprot id: A0A0U4CNL5
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

2041:Aeryth RS05785
gene id: 2041:Aeryth_RS05785
uniprot id: A0A0U4CM84
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

2041:Aeryth RS02825
gene id: 2041:Aeryth_RS02825
uniprot id: A0A0U4CLX2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

2041:Aeryth RS02780
gene id: 2041:Aeryth_RS02780
uniprot id: A0A0U3KFB2
names: Similarity
messages: Belongs to the CFA/CMAS family.

2041:Aeryth RS05415
gene id: 2041:Aeryth_RS05415
uniprot id: A0A0U3KGN7
names: Similarity
messages: Belongs to the FPG family.

2041:Aeryth RS05900
gene id: 2041:Aeryth_RS05900
uniprot id: A0A0U4CTZ0
names: Similarity
messages: Belongs to the Nudix hydrolase family.

2041:Aeryth RS03165
gene id: 2041:Aeryth_RS03165
uniprot id: A0A0U4CSA8
names: Subcellular Location Annotation
messages: Membrane

2041:Aeryth RS12985
gene id: 2041:Aeryth_RS12985
uniprot id: A0A0U3T4B4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

2041:Aeryth RS01010
gene id: 2041:Aeryth_RS01010
uniprot id: A0A0U4B665
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

2041:Aeryth RS01305
gene id: 2041:Aeryth_RS01305
uniprot id: A0A0U3SY34
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class II aldolase/RraA-like family.
messages: Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2-oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions.
messages: Homotrimer.

2041:Aeryth RS09715
gene id: 2041:Aeryth_RS09715
uniprot id: A0A0U4C1Y8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

2041:Aeryth RS07810
gene id: 2041:Aeryth_RS07810
uniprot id: A0A0U4C9R5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

2041:Aeryth RS03120
gene id: 2041:Aeryth_RS03120
uniprot id: A0A0U4CE85
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

2041:Aeryth RS02375
gene id: 2041:Aeryth_RS02375
uniprot id: A0A0U3SYI9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

2041:Aeryth RS03425
gene id: 2041:Aeryth_RS03425
uniprot id: A0A0U4C795
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

2041:Aeryth RS09250
gene id: 2041:Aeryth_RS09250
uniprot id: A0A0U3TH13
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

2041:Aeryth RS15145
gene id: 2041:Aeryth_RS15145
uniprot id: A0A0U4CS54
names: Function
names: Similarity
messages: Belongs to the ApbE family.
messages: Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.

2041:Aeryth RS10730
gene id: 2041:Aeryth_RS10730
uniprot id: A0A0U4CIE1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Rieske iron-sulfur protein family.
messages: Cell membrane
messages: Iron-sulfur subunit of the cytochrome bc1 complex, an essential component of the respiratory electron transport chain required for ATP synthesis. The bc1 complex catalyzes the oxidation of menaquinol and the reduction of cytochrome c in the respiratory chain. The bc1 complex operates through a Q-cycle mechanism that couples electron transfer to generation of the proton gradient that drives ATP synthesis.
messages: Membrane

2041:Aeryth RS11060
gene id: 2041:Aeryth_RS11060
uniprot id: A0A0U4BBQ8
names: Function
names: Similarity
messages: Belongs to the GlnE family.
messages: Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell.

2041:Aeryth RS00575
gene id: 2041:Aeryth_RS00575
uniprot id: A0A0U4B5Z0
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20 family.
messages: Binds 2 Zn(2+) ions per subunit.

2041:Aeryth RS10710
gene id: 2041:Aeryth_RS10710
uniprot id: A0A0U4BIU6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2041:Aeryth RS14355
gene id: 2041:Aeryth_RS14355
uniprot id: A0A0U4BKZ1
names: Subcellular Location Annotation
messages: Membrane

2041:Aeryth RS03300
gene id: 2041:Aeryth_RS03300
uniprot id: A0A0U3SZ71
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

2041:Aeryth RS13450
gene id: 2041:Aeryth_RS13450
uniprot id: A0A0U4CCN6
names: Similarity
messages: Belongs to the citrate synthase family.

2041:Aeryth RS01295
gene id: 2041:Aeryth_RS01295
uniprot id: A0A0U4CJR2
names: Similarity
messages: Belongs to the acyl-CoA oxidase family.

2041:Aeryth RS03485
gene id: 2041:Aeryth_RS03485
uniprot id: A0A0U3TE48
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

2041:Aeryth RS06605
gene id: 2041:Aeryth_RS06605
uniprot id: A0A0U4C957
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

2041:Aeryth RS02770
gene id: 2041:Aeryth_RS02770
uniprot id: A0A0U4BE88
names: Similarity
messages: Belongs to the pirin family.

2041:Aeryth RS13985
gene id: 2041:Aeryth_RS13985
uniprot id: A0A0U4C441
names: Subcellular Location Annotation
messages: Membrane

2041:Aeryth RS02595
gene id: 2041:Aeryth_RS02595
uniprot id: A0A0U4B714
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

2041:Aeryth RS01005
gene id: 2041:Aeryth_RS01005
uniprot id: A0A0U3KEE2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

2041:Aeryth RS07020
gene id: 2041:Aeryth_RS07020
uniprot id: A0A0U4CP98
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2041:Aeryth RS14935
gene id: 2041:Aeryth_RS14935
uniprot id: A0A0U4B028
names: Similarity
messages: Belongs to the lysine N(6)-hydroxylase/L-ornithine N(5)-oxygenase family.

2041:Aeryth RS10465
gene id: 2041:Aeryth_RS10465
uniprot id: A0A0U3KJU8
names: Subcellular Location Annotation
messages: Cytoplasm

2041:Aeryth RS09700
gene id: 2041:Aeryth_RS09700
uniprot id: A0A0U4CQQ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

2041:Aeryth RS13635
gene id: 2041:Aeryth_RS13635
uniprot id: A0A0U4BKJ1
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

2041:Aeryth RS03235
gene id: 2041:Aeryth_RS03235
uniprot id: A0A0U4C6I8
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

2041:Aeryth RS13575
gene id: 2041:Aeryth_RS13575
uniprot id: A0A0U4CJW3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

2041:Aeryth RS05395
gene id: 2041:Aeryth_RS05395
uniprot id: A0A0U4BZ93
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

2041:Aeryth RS11825
gene id: 2041:Aeryth_RS11825
uniprot id: A0A0U4CBJ2
names: Subcellular Location Annotation
messages: Membrane

2041:Aeryth RS15455
gene id: 2041:Aeryth_RS15455
uniprot id: A0A0U4CTM5
names: Subcellular Location Annotation
messages: Membrane

2041:Aeryth RS01855
gene id: 2041:Aeryth_RS01855
uniprot id: A0A0U3SYA3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2041:Aeryth RS16795
gene id: 2041:Aeryth_RS16795
uniprot id: A0A0U4CED2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

2041:Aeryth RS12025
gene id: 2041:Aeryth_RS12025
uniprot id: A0A0U4CBQ6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

2041:Aeryth RS02940
gene id: 2041:Aeryth_RS02940
uniprot id: A0A0U4D690
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.

2041:Aeryth RS05710
gene id: 2041:Aeryth_RS05710
uniprot id: A0A0U3T0F9
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

2041:Aeryth RS09235
gene id: 2041:Aeryth_RS09235
uniprot id: A0A0U4BAQ4
names: Similarity
messages: Belongs to the band 7/mec-2 family.

2041:Aeryth RS03360
gene id: 2041:Aeryth_RS03360
uniprot id: A0A0U4D6H7
names: Similarity
messages: Belongs to the UPF0234 family.

2041:Aeryth RS11075
gene id: 2041:Aeryth_RS11075
uniprot id: A0A0U3TI03
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2041:Aeryth RS11350
gene id: 2041:Aeryth_RS11350
uniprot id: A0A0U3TI52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

2041:Aeryth RS06695
gene id: 2041:Aeryth_RS06695
uniprot id: A0A0U4BZX3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

2041:Aeryth RS02950
gene id: 2041:Aeryth_RS02950
uniprot id: A0A0U4B785
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

2041:Aeryth RS13830
gene id: 2041:Aeryth_RS13830
uniprot id: A0A0U4CK12
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

2041:Aeryth RS15805
gene id: 2041:Aeryth_RS15805
uniprot id: Q5Y9I4
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

2041:Aeryth RS12740
gene id: 2041:Aeryth_RS12740
uniprot id: A0A0U4CXT0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

2041:Aeryth RS12430
gene id: 2041:Aeryth_RS12430
uniprot id: A0A0U4CQT0
names: Subcellular Location Annotation
messages: Membrane

2041:Aeryth RS16130
gene id: 2041:Aeryth_RS16130
uniprot id: A0A0U3T693
names: Similarity
messages: Belongs to the shaker potassium channel beta subunit family.

2041:Aeryth RS09905
gene id: 2041:Aeryth_RS09905
uniprot id: A0A0U3KJJ2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Catalyzes the conjugation of the 1'-hydroxyl group of D-myo-inositol-3-phosphate (also named L-myo-inositol-1-phosphate) with a lipid tail of cytidine diphosphate diacylglycerol (CDP-DAG), forming phosphatidylinositol phosphate (PIP) and CMP. PIP is a precursor of phosphatidylinositol (PI) which is an essential lipid required for cell wall formation.
messages: Cell membrane
messages: Contains a di-nuclear catalytic Mg(2+) center.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

2041:Aeryth RS07665
gene id: 2041:Aeryth_RS07665
uniprot id: A0A0U3KI38
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the kynureninase family.
messages: Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2041:Aeryth RS00265
gene id: 2041:Aeryth_RS00265
uniprot id: A0A0U4CKL3
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

2041:Aeryth RS04145
gene id: 2041:Aeryth_RS04145
uniprot id: A0A0U4C7M8
names: Cofactor
names: Function
messages: Binds 1 [3Fe-4S] cluster.
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

2041:Aeryth RS06800
gene id: 2041:Aeryth_RS06800
uniprot id: A0A0U3KHI0
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

2041:Aeryth RS00115
gene id: 2041:Aeryth_RS00115
uniprot id: A0A0U4CQV2
names: Subcellular Location Annotation
messages: Membrane

2041:Aeryth RS12895
gene id: 2041:Aeryth_RS12895
uniprot id: A0A0U4BCC8
names: Similarity
messages: Belongs to the serine/threonine dehydratase family.

2041:Aeryth RS11095
gene id: 2041:Aeryth_RS11095
uniprot id: A0A0U4CB26
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

2041:Aeryth RS09020
gene id: 2041:Aeryth_RS09020
uniprot id: A0A0U4CAL7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MshC subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent condensation of GlcN-Ins and L-cysteine to form L-Cys-GlcN-Ins.
messages: Monomer.

2041:Aeryth RS13500
gene id: 2041:Aeryth_RS13500
uniprot id: A0A0U3TJ96
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

2041:Aeryth RS02615
gene id: 2041:Aeryth_RS02615
uniprot id: A0A0U3SYT2
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

2041:Aeryth RS09575
gene id: 2041:Aeryth_RS09575
uniprot id: A0A0U3KJD2
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

2041:Aeryth RS03270
gene id: 2041:Aeryth_RS03270
uniprot id: A0A0U4D6G0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 30 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

2041:Aeryth RS13605
gene id: 2041:Aeryth_RS13605
uniprot id: A0A0U4CCN8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

2041:Aeryth RS06625
gene id: 2041:Aeryth_RS06625
uniprot id: A0A0U4D883
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

2041:Aeryth RS13505
gene id: 2041:Aeryth_RS13505
uniprot id: A0A0U3T4T6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

2041:Aeryth RS03705
gene id: 2041:Aeryth_RS03705
uniprot id: A0A0U4CMC8
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

2041:Aeryth RS14625
gene id: 2041:Aeryth_RS14625
uniprot id: A0A0U4BDV6
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

2041:Aeryth RS05020
gene id: 2041:Aeryth_RS05020
uniprot id: A0A0U4C7F0
names: Similarity
messages: Belongs to the phosphohexose mutase family.

2041:Aeryth RS12290
gene id: 2041:Aeryth_RS12290
uniprot id: A0A0U4CC80
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

2041:Aeryth RS05480
gene id: 2041:Aeryth_RS05480
uniprot id: A0A0U4C8M0
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

2041:Aeryth RS07040
gene id: 2041:Aeryth_RS07040
uniprot id: A0A0U4AVQ9
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2041:Aeryth RS05965
gene id: 2041:Aeryth_RS05965
uniprot id: A0A0U3T0I0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0182 family.
messages: Cell membrane

2041:Aeryth RS04660
gene id: 2041:Aeryth_RS04660
uniprot id: A0A0U3SZW6
names: Similarity
messages: Belongs to the GSP E family.

2041:Aeryth RS07615
gene id: 2041:Aeryth_RS07615
uniprot id: A0A0U4B9F6
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

2041:Aeryth RS15565
gene id: 2041:Aeryth_RS15565
uniprot id: A0A0U4BLP2
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

2041:Aeryth RS10430
gene id: 2041:Aeryth_RS10430
uniprot id: A0A0U4CWI3
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

2041:Aeryth RS14335
gene id: 2041:Aeryth_RS14335
uniprot id: A0A0U4CYQ3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PstS family.
messages: Part of the ABC transporter complex PstSACB involved in phosphate import.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

2041:Aeryth RS12550
gene id: 2041:Aeryth_RS12550
uniprot id: A0A0U3T427
names: Similarity
messages: Belongs to the DNA photolyase family.

2041:Aeryth RS00795
gene id: 2041:Aeryth_RS00795
uniprot id: A0A0U4C5C3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2041:Aeryth RS15355
gene id: 2041:Aeryth_RS15355
uniprot id: A0A0U4CDL8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PNT beta subunit family.
messages: Cell inner membrane
messages: Membrane
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

2041:Aeryth RS14995
gene id: 2041:Aeryth_RS14995
uniprot id: A0A0U4CTE1
names: Similarity
messages: Belongs to the EccD/Snm4 family.

2041:Aeryth RS12105
gene id: 2041:Aeryth_RS12105
uniprot id: A0A0U3T3S2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 2 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

2041:Aeryth RS10375
gene id: 2041:Aeryth_RS10375
uniprot id: A0A0U4BBB5
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

2041:Aeryth RS08515
gene id: 2041:Aeryth_RS08515
uniprot id: A0A0U4C181
names: Similarity
messages: Belongs to the DNA glycosylase MPG family.

2041:Aeryth RS15815
gene id: 2041:Aeryth_RS15815
uniprot id: Q5Y9I2
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.

2041:Aeryth RS03880
gene id: 2041:Aeryth_RS03880
uniprot id: A0A0U4C7H5
names: Caution
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2041:Aeryth RS04975
gene id: 2041:Aeryth_RS04975
uniprot id: A0A0U3KGG2
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

2041:Aeryth RS10665
gene id: 2041:Aeryth_RS10665
uniprot id: A0A0U3T2X5
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

2041:Aeryth RS08760
gene id: 2041:Aeryth_RS08760
uniprot id: A0A0U4CVN4
names: Activity Regulation
names: Caution
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2041:Aeryth RS13490
gene id: 2041:Aeryth_RS13490
uniprot id: A0A0U4CJV2
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

2041:Aeryth RS02490
gene id: 2041:Aeryth_RS02490
uniprot id: A0A0U4BXP4
names: Similarity
messages: Belongs to the adenylyl cyclase class-3 family.

2041:Aeryth RS00035
gene id: 2041:Aeryth_RS00035
uniprot id: A0A0U4ARW6
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

2041:Aeryth RS11810
gene id: 2041:Aeryth_RS11810
uniprot id: A0A0U3T3X2
names: Subcellular Location Annotation
messages: Membrane

2041:Aeryth RS01930
gene id: 2041:Aeryth_RS01930
uniprot id: A0A0U3TDB9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

2041:Aeryth RS05355
gene id: 2041:Aeryth_RS05355
uniprot id: A0A0U3T088
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

2041:Aeryth RS13285
gene id: 2041:Aeryth_RS13285
uniprot id: A0A0U4C3Q3
names: Subcellular Location Annotation
messages: Membrane
messages: Nucleus membrane

2041:Aeryth RS00995
gene id: 2041:Aeryth_RS00995
uniprot id: A0A0U4BDC7
names: Similarity
messages: Belongs to the Rv1128c/1148c/1588c/1702c/1945/3466 family.

2041:Aeryth RS05745
gene id: 2041:Aeryth_RS05745
uniprot id: A0A0U4BZG2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhD family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.

2041:Aeryth RS07350
gene id: 2041:Aeryth_RS07350
uniprot id: A0A0U4B9A7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

2041:Aeryth RS01405
gene id: 2041:Aeryth_RS01405
uniprot id: A0A0U4B5X0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

2041:Aeryth RS15100
gene id: 2041:Aeryth_RS15100
uniprot id: A0A0U4C4Q2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

2041:Aeryth RS14215
gene id: 2041:Aeryth_RS14215
uniprot id: A0A0U3T561
names: Cofactor
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 1 family.
messages: Binds 1 zinc ion per subunit.

2041:Aeryth RS07510
gene id: 2041:Aeryth_RS07510
uniprot id: A0A0U3TG41
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

2041:Aeryth RS07900
gene id: 2041:Aeryth_RS07900
uniprot id: A0A0U4C9T0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

2041:Aeryth RS12530
gene id: 2041:Aeryth_RS12530
uniprot id: A0A0U4CQU4
names: Similarity
messages: Belongs to the CFA/CMAS family.

2041:Aeryth RS08200
gene id: 2041:Aeryth_RS08200
uniprot id: A0A0U4BA43
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Catalyzes the reversible hydration of carbon dioxide to form bicarbonate.

2041:Aeryth RS07160
gene id: 2041:Aeryth_RS07160
uniprot id: A0A0U4CGD7
names: Subcellular Location Annotation
messages: Membrane

2041:Aeryth RS16170
gene id: 2041:Aeryth_RS16170
uniprot id: A0A0U4CE23
names: Similarity
messages: Belongs to the arginine deiminase family.

2041:Aeryth RS07275
gene id: 2041:Aeryth_RS07275
uniprot id: A0A0U4C8X2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

2041:Aeryth RS07215
gene id: 2041:Aeryth_RS07215
uniprot id: A0A0U4C0E9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of glycine to tRNA(Gly).
messages: Cytoplasm
messages: Homodimer.

2041:Aeryth RS16735
gene id: 2041:Aeryth_RS16735
uniprot id: A0A0U4DDR2
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

2041:Aeryth RS08725
gene id: 2041:Aeryth_RS08725
uniprot id: A0A0U4CNW4
names: Subcellular Location Annotation
messages: Membrane

2041:Aeryth RS02380
gene id: 2041:Aeryth_RS02380
uniprot id: A0A0U4C649
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cell surface
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
messages: capsule
messages: cell wall

2041:Aeryth RS06165
gene id: 2041:Aeryth_RS06165
uniprot id: A0A0U3KH62
names: Function
names: Similarity
messages: Belongs to the KptA/TPT1 family.
messages: Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP-ribose 1''-2''-cyclic phosphate (APPR>P). May function as an ADP-ribosylase.

2041:Aeryth RS01550
gene id: 2041:Aeryth_RS01550
uniprot id: A0A0U4BDK9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2041:Aeryth RS04070
gene id: 2041:Aeryth_RS04070
uniprot id: A0A0U4BF04
names: Subcellular Location Annotation
messages: Membrane

2041:Aeryth RS05910
gene id: 2041:Aeryth_RS05910
uniprot id: A0A0U4BZI6
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

2041:Aeryth RS14165
gene id: 2041:Aeryth_RS14165
uniprot id: A0A0U4CD15
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

2041:Aeryth RS06870
gene id: 2041:Aeryth_RS06870
uniprot id: A0A0U4AVM4
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta subunit.
messages: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

2041:Aeryth RS09695
gene id: 2041:Aeryth_RS09695
uniprot id: A0A0U4CAC6
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

2041:Aeryth RS16120
gene id: 2041:Aeryth_RS16120
uniprot id: A0A0U4CSK1
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

2041:Aeryth RS03025
gene id: 2041:Aeryth_RS03025
uniprot id: A0A0U4D6A8
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

2041:Aeryth RS15850
gene id: 2041:Aeryth_RS15850
uniprot id: Q5Y9H5
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.

2041:Aeryth RS06225
gene id: 2041:Aeryth_RS06225
uniprot id: A0A0U4CNS4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

2041:Aeryth RS08465
gene id: 2041:Aeryth_RS08465
uniprot id: A0A0U4CH73
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

2041:Aeryth RS12490
gene id: 2041:Aeryth_RS12490
uniprot id: A0A0U4C3B3
names: Cofactor
messages: Can also use Mn(2+) ion.

2041:Aeryth RS11370
gene id: 2041:Aeryth_RS11370
uniprot id: A0A0U3T3A1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

2041:Aeryth RS08345
gene id: 2041:Aeryth_RS08345
uniprot id: A0A0U4CA86
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.

2041:Aeryth RS15995
gene id: 2041:Aeryth_RS15995
uniprot id: A0A0U4C558
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

2041:Aeryth RS11765
gene id: 2041:Aeryth_RS11765
uniprot id: A0A0U4AYB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

2041:Aeryth RS16605
gene id: 2041:Aeryth_RS16605
uniprot id: A0A0U4CE99
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

2041:Aeryth RS13515
gene id: 2041:Aeryth_RS13515
uniprot id: A0A0U3T4K2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

2041:Aeryth RS05530
gene id: 2041:Aeryth_RS05530
uniprot id: A0A0U3T0D0
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

2041:Aeryth RS14340
gene id: 2041:Aeryth_RS14340
uniprot id: A0A0U4CD47
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

2041:Aeryth RS12765
gene id: 2041:Aeryth_RS12765
uniprot id: A0A0U4DBI7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

2041:Aeryth RS16095
gene id: 2041:Aeryth_RS16095
uniprot id: A0A0U4BLZ2
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.

2041:Aeryth RS02750
gene id: 2041:Aeryth_RS02750
uniprot id: A0A0U4C6X0
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

2041:Aeryth RS11920
gene id: 2041:Aeryth_RS11920
uniprot id: A0A0U4CRW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

2041:Aeryth RS09300
gene id: 2041:Aeryth_RS09300
uniprot id: A0A0U4C1R6
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.

2041:Aeryth RS04710
gene id: 2041:Aeryth_RS04710
uniprot id: A0A0U4BFB8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Belongs to the precorrin methyltransferase family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

2041:Aeryth RS16010
gene id: 2041:Aeryth_RS16010
uniprot id: A0A0U4DDD3
names: Similarity
names: Subunit
messages: Belongs to the Bpa family.
messages: Forms a homooligomeric, either hexameric or heptameric, ring-like structure which stacks co-axially with the proteasomal alpha-rings.

2041:Aeryth RS03735
gene id: 2041:Aeryth_RS03735
uniprot id: A0A0U4D6P1
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

2041:Aeryth RS03970
gene id: 2041:Aeryth_RS03970
uniprot id: A0A0U4C7J6
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

2041:Aeryth RS06630
gene id: 2041:Aeryth_RS06630
uniprot id: A0A0U3KHD7
names: Function
names: Similarity
messages: Belongs to the threonine synthase family.
messages: Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.

2041:Aeryth RS02705
gene id: 2041:Aeryth_RS02705
uniprot id: A0A0U4CKG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2041:Aeryth RS08430
gene id: 2041:Aeryth_RS08430
uniprot id: A0A0U4CAA5
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

2041:Aeryth RS11565
gene id: 2041:Aeryth_RS11565
uniprot id: A0A0U3T3D7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

2041:Aeryth RS08475
gene id: 2041:Aeryth_RS08475
uniprot id: A0A0U3TGL5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

2041:Aeryth RS10835
gene id: 2041:Aeryth_RS10835
uniprot id: A0A0U4BBA3
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

2041:Aeryth RS10535
gene id: 2041:Aeryth_RS10535
uniprot id: A0A0U4AXN5
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

2041:Aeryth RS10100
gene id: 2041:Aeryth_RS10100
uniprot id: A0A0U3KJN4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2041:Aeryth RS08355
gene id: 2041:Aeryth_RS08355
uniprot id: A0A0U4AWG9
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

2041:Aeryth RS01545
gene id: 2041:Aeryth_RS01545
uniprot id: A0A0U4ASP9
names: Function
names: Similarity
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids lysine, threonine, isoleucine and methionine.

2041:Aeryth RS15595
gene id: 2041:Aeryth_RS15595
uniprot id: A0A0U3TKJ9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
messages: Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

2041:Aeryth RS00415
gene id: 2041:Aeryth_RS00415
uniprot id: A0A0U4CCV6
names: Subcellular Location Annotation
messages: Membrane

2041:Aeryth RS03460
gene id: 2041:Aeryth_RS03460
uniprot id: A0A0U4B7I5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2041:Aeryth RS17555
gene id: 2041:Aeryth_RS17555
uniprot id: A0A0U3SYJ9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the DyP-type peroxidase family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group non-covalently per subunit.
messages: Involved in the recovery of exogenous heme iron. Extracts iron from heme while preserving the protoporphyrin ring intact.

2041:Aeryth RS12640
gene id: 2041:Aeryth_RS12640
uniprot id: A0A0U4CC41
names: Subcellular Location Annotation
messages: Membrane

2041:Aeryth RS09540
gene id: 2041:Aeryth_RS09540
uniprot id: A0A0U4CQM0
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

2041:Aeryth RS06710
gene id: 2041:Aeryth_RS06710
uniprot id: A0A0U4D8A8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

2041:Aeryth RS07755
gene id: 2041:Aeryth_RS07755
uniprot id: A0A0U4B9U3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

2041:Aeryth RS17055
gene id: 2041:Aeryth_RS17055
uniprot id: A0A0U4BML9
names: Subcellular Location Annotation
messages: Membrane

2041:Aeryth RS13855
gene id: 2041:Aeryth_RS13855
uniprot id: A0A0U3T4S2
names: Subcellular Location Annotation
messages: Membrane

2041:Aeryth RS00015
gene id: 2041:Aeryth_RS00015
uniprot id: A0A0U4CKH4
names: Similarity
messages: Belongs to the 6-phosphogluconate dehydrogenase family.

2041:Aeryth RS02190
gene id: 2041:Aeryth_RS02190
uniprot id: A0A0U4CK70
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

2041:Aeryth RS07270
gene id: 2041:Aeryth_RS07270
uniprot id: A0A0U3T157
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell inner membrane
messages: Membrane

2041:Aeryth RS02495
gene id: 2041:Aeryth_RS02495
uniprot id: A0A0U4AT78
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

2041:Aeryth RS11580
gene id: 2041:Aeryth_RS11580
uniprot id: A0A0U4CX64
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

2041:Aeryth RS10365
gene id: 2041:Aeryth_RS10365
uniprot id: A0A0U4DA87
names: Subcellular Location Annotation
messages: Membrane

2041:Aeryth RS08260
gene id: 2041:Aeryth_RS08260
uniprot id: A0A0U4CA68
names: Subcellular Location Annotation
messages: Membrane

2041:Aeryth RS10440
gene id: 2041:Aeryth_RS10440
uniprot id: A0A0U4C290
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

2041:Aeryth RS12595
gene id: 2041:Aeryth_RS12595
uniprot id: A0A0U3KL81
names: Similarity
messages: Belongs to the phosphohexose mutase family.

2041:Aeryth RS09720
gene id: 2041:Aeryth_RS09720
uniprot id: A0A0U4AX87
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

2041:Aeryth RS12175
gene id: 2041:Aeryth_RS12175
uniprot id: A0A0U3T428
names: Subcellular Location Annotation
messages: Membrane

2041:Aeryth RS15260
gene id: 2041:Aeryth_RS15260
uniprot id: A0A0U4BDT6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the arabinose isomerase family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the conversion of L-arabinose to L-ribulose.

2041:Aeryth RS06645
gene id: 2041:Aeryth_RS06645
uniprot id: A0A0U4CMP0
names: Similarity
messages: Belongs to the glutathione peroxidase family.

2041:Aeryth RS04380
gene id: 2041:Aeryth_RS04380
uniprot id: A0A0U3TEN5
names: Similarity
messages: Belongs to the peptidase M1 family.

2041:Aeryth RS02795
gene id: 2041:Aeryth_RS02795
uniprot id: A0A0U4CKI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

2041:Aeryth RS11595
gene id: 2041:Aeryth_RS11595
uniprot id: A0A0U4AY89
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

2041:Aeryth RS00875
gene id: 2041:Aeryth_RS00875
uniprot id: A0A0U3SXT4
names: Subcellular Location Annotation
messages: Membrane

2041:Aeryth RS02320
gene id: 2041:Aeryth_RS02320
uniprot id: A0A0U4BXL0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cell surface
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
messages: capsule
messages: cell wall

2041:Aeryth RS16630
gene id: 2041:Aeryth_RS16630
uniprot id: A0A0U4BMB5
names: Subcellular Location Annotation
messages: Membrane

2041:Aeryth RS09870
gene id: 2041:Aeryth_RS09870
uniprot id: A0A0U4CQU2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

2041:Aeryth RS02785
gene id: 2041:Aeryth_RS02785
uniprot id: A0A0U4B748
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

2041:Aeryth RS10510
gene id: 2041:Aeryth_RS10510
uniprot id: A0A0U4CR83
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

2041:Aeryth RS09080
gene id: 2041:Aeryth_RS09080
uniprot id: A0A0U3T2F1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

2041:Aeryth RS07080
gene id: 2041:Aeryth_RS07080
uniprot id: A0A0U3T159
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 2 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

2041:Aeryth RS12875
gene id: 2041:Aeryth_RS12875
uniprot id: A0A0U4CR00
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl-inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics.
messages: Belongs to the MshB deacetylase family. Mca subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Monomer.

2041:Aeryth RS10530
gene id: 2041:Aeryth_RS10530
uniprot id: A0A0U4C2C0
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

2041:Aeryth RS11135
gene id: 2041:Aeryth_RS11135
uniprot id: A0A0U4DAP4
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

2041:Aeryth RS06910
gene id: 2041:Aeryth_RS06910
uniprot id: A0A0U3T127
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-C family. DnaE2 subfamily.
messages: Cytoplasm
messages: DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase.

2041:Aeryth RS04970
gene id: 2041:Aeryth_RS04970
uniprot id: A0A0U4D7C2
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

2041:Aeryth RS10595
gene id: 2041:Aeryth_RS10595
uniprot id: A0A0U4CR98
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

2041:Aeryth RS04410
gene id: 2041:Aeryth_RS04410
uniprot id: A0A0U4CT49
names: Function
messages: Catalyzes the reduction of sulfite to sulfide, a step in the biosynthesis of sulfur-containing amino acids and cofactors.

2041:Aeryth RS09035
gene id: 2041:Aeryth_RS09035
uniprot id: A0A0U4BHZ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mediates influx of magnesium ions.
messages: Membrane

2041:Aeryth RS13710
gene id: 2041:Aeryth_RS13710
uniprot id: A0A0U4AZC9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

2041:Aeryth RS04890
gene id: 2041:Aeryth_RS04890
uniprot id: A0A0U4D7A4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

2041:Aeryth RS01515
gene id: 2041:Aeryth_RS01515
uniprot id: A0A0U4C5P7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

2041:Aeryth RS15645
gene id: 2041:Aeryth_RS15645
uniprot id: A0A0U4B0G2
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.

2041:Aeryth RS10145
gene id: 2041:Aeryth_RS10145
uniprot id: A0A0U4CQY4
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

2041:Aeryth RS15280
gene id: 2041:Aeryth_RS15280
uniprot id: A0A0U4CZB4
names: Subcellular Location Annotation
messages: Membrane

2041:Aeryth RS06955
gene id: 2041:Aeryth_RS06955
uniprot id: A0A0U4AVP3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2041:Aeryth RS11980
gene id: 2041:Aeryth_RS11980
uniprot id: A0A0U4BC86
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

2041:Aeryth RS09685
gene id: 2041:Aeryth_RS09685
uniprot id: A0A0U4BAP5
names: Similarity
messages: Belongs to the ABC transporter superfamily.

2041:Aeryth RS15725
gene id: 2041:Aeryth_RS15725
uniprot id: A0A0U4CTT4
names: Subcellular Location Annotation
messages: Membrane

2041:Aeryth RS02035
gene id: 2041:Aeryth_RS02035
uniprot id: A0A0U4B685
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

2041:Aeryth RS12350
gene id: 2041:Aeryth_RS12350
uniprot id: A0A0U3T3Z6
names: Similarity
messages: Belongs to the TlyA family.

2041:Aeryth RS10565
gene id: 2041:Aeryth_RS10565
uniprot id: A0A0U4CPV9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

2041:Aeryth RS05445
gene id: 2041:Aeryth_RS05445
uniprot id: A0A0U3TF65
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

2041:Aeryth RS15285
gene id: 2041:Aeryth_RS15285
uniprot id: A0A0U4CDN1
names: Subcellular Location Annotation
messages: Membrane

2041:Aeryth RS12935
gene id: 2041:Aeryth_RS12935
uniprot id: A0A0U4BK47
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

2041:Aeryth RS05645
gene id: 2041:Aeryth_RS05645
uniprot id: A0A0U4CTT9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type 2 tetrahydrodipicolinate N-succinyltransferase family.
messages: Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2-amino-6-oxopimelate using succinyl-CoA.
messages: Cytoplasm
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2041:Aeryth RS14515
gene id: 2041:Aeryth_RS14515
uniprot id: A0A0U4C4C8
names: Similarity
messages: Belongs to the cytochrome P450 family.

2041:Aeryth RS06965
gene id: 2041:Aeryth_RS06965
uniprot id: A0A0U4D8F8
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

2041:Aeryth RS15050
gene id: 2041:Aeryth_RS15050
uniprot id: A0A0U4CS34
names: Similarity
messages: Belongs to the universal stress protein A family.

2041:Aeryth RS08510
gene id: 2041:Aeryth_RS08510
uniprot id: A0A0U4CAB9
names: Similarity
messages: Belongs to the peptidase M1 family.

2041:Aeryth RS12885
gene id: 2041:Aeryth_RS12885
uniprot id: A0A0U3T4H1
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

2041:Aeryth RS12325
gene id: 2041:Aeryth_RS12325
uniprot id: A0A0U4CJ57
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2041:Aeryth RS12970
gene id: 2041:Aeryth_RS12970
uniprot id: A0A0U3TJ10
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2041:Aeryth RS12905
gene id: 2041:Aeryth_RS12905
uniprot id: A0A0U4CCD0
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

2041:Aeryth RS03785
gene id: 2041:Aeryth_RS03785
uniprot id: A0A0U4CME3
names: Subcellular Location Annotation
messages: Membrane

2041:Aeryth RS03290
gene id: 2041:Aeryth_RS03290
uniprot id: A0A0U4CKT5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the complex I 75 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

2041:Aeryth RS13885
gene id: 2041:Aeryth_RS13885
uniprot id: A0A0U4AZG7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

2041:Aeryth RS04155
gene id: 2041:Aeryth_RS04155
uniprot id: A0A0U4AU95
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpA family.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds the extracellular potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

2041:Aeryth RS06510
gene id: 2041:Aeryth_RS06510
uniprot id: A0A0U4CNZ4
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

2041:Aeryth RS12190
gene id: 2041:Aeryth_RS12190
uniprot id: A0A0U4CBU5
names: Similarity
messages: Belongs to the TPP enzyme family.

2041:Aeryth RS15110
gene id: 2041:Aeryth_RS15110
uniprot id: A0A0U4BLE8
names: Similarity
messages: Belongs to the universal stress protein A family.

2041:Aeryth RS04860
gene id: 2041:Aeryth_RS04860
uniprot id: A0A0U4CTD4
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

2041:Aeryth RS14620
gene id: 2041:Aeryth_RS14620
uniprot id: A0A0U3KME4
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family.

2041:Aeryth RS13580
gene id: 2041:Aeryth_RS13580
uniprot id: A0A0U4CRB1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

2041:Aeryth RS13585
gene id: 2041:Aeryth_RS13585
uniprot id: A0A0U3TJB3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

2041:Aeryth RS04445
gene id: 2041:Aeryth_RS04445
uniprot id: A0A0U4B823
names: Similarity
messages: Belongs to the FPG family.

2041:Aeryth RS08600
gene id: 2041:Aeryth_RS08600
uniprot id: A0A0U4CAD2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sbp family.
messages: Cell membrane

2041:Aeryth RS09320
gene id: 2041:Aeryth_RS09320
uniprot id: A0A0U3KJ93
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

2041:Aeryth RS07300
gene id: 2041:Aeryth_RS07300
uniprot id: A0A0U4C0G9
names: Similarity
messages: Belongs to the P(II) protein family.

2041:Aeryth RS14630
gene id: 2041:Aeryth_RS14630
uniprot id: A0A0U4CKG3
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

2041:Aeryth RS17190
gene id: 2041:Aeryth_RS17190
uniprot id: A0A0U4CEW1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

2041:Aeryth RS03225
gene id: 2041:Aeryth_RS03225
uniprot id: A0A0U4B6Y5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TPP enzyme family. MenD subfamily.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
messages: Homodimer.

2041:Aeryth RS17100
gene id: 2041:Aeryth_RS17100
uniprot id: A0A0U3T6N9
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

2041:Aeryth RS11080
gene id: 2041:Aeryth_RS11080
uniprot id: A0A0U3T3H0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

2041:Aeryth RS09885
gene id: 2041:Aeryth_RS09885
uniprot id: A0A0U4C221
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glutaminase PdxT/SNO family.
messages: Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.
messages: In the presence of PdxS, forms a dodecamer of heterodimers. Only shows activity in the heterodimer.

2041:Aeryth RS09385
gene id: 2041:Aeryth_RS09385
uniprot id: A0A0U4AX24
names: Similarity
messages: Belongs to the GPI family.

2041:Aeryth RS07035
gene id: 2041:Aeryth_RS07035
uniprot id: A0A0U4C068
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

2041:Aeryth RS03580
gene id: 2041:Aeryth_RS03580
uniprot id: A0A0U3SZC0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

2041:Aeryth RS09645
gene id: 2041:Aeryth_RS09645
uniprot id: A0A0U4BIA7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

2041:Aeryth RS02605
gene id: 2041:Aeryth_RS02605
uniprot id: A0A0U4CKE8
names: Subcellular Location Annotation
messages: Membrane

2041:Aeryth RS11460
gene id: 2041:Aeryth_RS11460
uniprot id: A0A0U3TI81
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

2041:Aeryth RS10425
gene id: 2041:Aeryth_RS10425
uniprot id: A0A0U4CR60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

2041:Aeryth RS08290
gene id: 2041:Aeryth_RS08290
uniprot id: A0A0U3KIL5
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

2041:Aeryth RS06440
gene id: 2041:Aeryth_RS06440
uniprot id: A0A0U4BGD5
names: Subcellular Location Annotation
messages: Membrane

2041:Aeryth RS16395
gene id: 2041:Aeryth_RS16395
uniprot id: A0A0U3T6D7
names: Subcellular Location Annotation
messages: Membrane

2041:Aeryth RS15495
gene id: 2041:Aeryth_RS15495
uniprot id: A0A0U4BEC6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

2041:Aeryth RS00125
gene id: 2041:Aeryth_RS00125
uniprot id: A0A0U4ARY0
names: Similarity
messages: Belongs to the pirin family.

2041:Aeryth RS09400
gene id: 2041:Aeryth_RS09400
uniprot id: A0A0U3KJA8
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

2041:Aeryth RS12510
gene id: 2041:Aeryth_RS12510
uniprot id: A0A0U3KL42
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

2041:Aeryth RS02230
gene id: 2041:Aeryth_RS02230
uniprot id: A0A0U4CRT3
names: Subcellular Location Annotation
messages: Membrane

2041:Aeryth RS17080
gene id: 2041:Aeryth_RS17080
uniprot id: A0A0U4CT63
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2041:Aeryth RS03860
gene id: 2041:Aeryth_RS03860
uniprot id: A0A0U4C6U7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

2041:Aeryth RS13735
gene id: 2041:Aeryth_RS13735
uniprot id: A0A0U4CJZ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.

2041:Aeryth RS12535
gene id: 2041:Aeryth_RS12535
uniprot id: A0A0U3TIS1
names: Subcellular Location Annotation
messages: Membrane

2041:Aeryth RS10115
gene id: 2041:Aeryth_RS10115
uniprot id: A0A0U4CPL1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oxidase-dependent Fe transporter (OFeT) (TC 9.A.10.1) family.
messages: Membrane

2041:Aeryth RS09690
gene id: 2041:Aeryth_RS09690
uniprot id: A0A0U3T2E7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2041:Aeryth RS12720
gene id: 2041:Aeryth_RS12720
uniprot id: A0A0U4BC98
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaved by autocatalysis into a large and a small subunit.
messages: This enzyme consists of two polypeptide chains, which are synthesized in precursor form from a single polypeptide.

2041:Aeryth RS04825
gene id: 2041:Aeryth_RS04825
uniprot id: A0A0U3TEX6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

2041:Aeryth RS09750
gene id: 2041:Aeryth_RS09750
uniprot id: A0A0U4CHV1
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

2041:Aeryth RS11065
gene id: 2041:Aeryth_RS11065
uniprot id: A0A0U4CIK1
names: Similarity
messages: Belongs to the glutamine synthetase family.

2041:Aeryth RS10790
gene id: 2041:Aeryth_RS10790
uniprot id: A0A0U4BIW4
names: Similarity
messages: Belongs to the PspA/IM30 family.

2041:Aeryth RS06890
gene id: 2041:Aeryth_RS06890
uniprot id: A0A0U4B9C3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

2041:Aeryth RS15970
gene id: 2041:Aeryth_RS15970
uniprot id: A0A0U4CE27
names: Subcellular Location Annotation
messages: Membrane

2041:Aeryth RS10135
gene id: 2041:Aeryth_RS10135
uniprot id: A0A0U3T2M9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

2041:Aeryth RS16675
gene id: 2041:Aeryth_RS16675
uniprot id: A0A0U3T6J5
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

2041:Aeryth RS09485
gene id: 2041:Aeryth_RS09485
uniprot id: A0A0U4BAV2
names: Subcellular Location Annotation
messages: Membrane

2041:Aeryth RS06435
gene id: 2041:Aeryth_RS06435
uniprot id: A0A0U4AVE1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

2041:Aeryth RS10900
gene id: 2041:Aeryth_RS10900
uniprot id: A0A0U4CQ30
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

2041:Aeryth RS10890
gene id: 2041:Aeryth_RS10890
uniprot id: A0A0U4BBL6
names: Subcellular Location Annotation
messages: Membrane

2041:Aeryth RS01710
gene id: 2041:Aeryth_RS01710
uniprot id: A0A0U4CRI0
names: Subcellular Location Annotation
messages: Membrane

2041:Aeryth RS12680
gene id: 2041:Aeryth_RS12680
uniprot id: A0A0U3KLC5
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

2041:Aeryth RS09600
gene id: 2041:Aeryth_RS09600
uniprot id: A0A0U3T2Q1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

2041:Aeryth RS04735
gene id: 2041:Aeryth_RS04735
uniprot id: A0A0U4CLJ8
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

2041:Aeryth RS02225
gene id: 2041:Aeryth_RS02225
uniprot id: A0A0U4CLL8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

2041:Aeryth RS04715
gene id: 2041:Aeryth_RS04715
uniprot id: A0A0U4D773
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily.
messages: Cytoplasm
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

2041:Aeryth RS11710
gene id: 2041:Aeryth_RS11710
uniprot id: A0A0U4CQG5
names: Subcellular Location Annotation
messages: Membrane

2041:Aeryth RS06700
gene id: 2041:Aeryth_RS06700
uniprot id: A0A0U4AVI8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

2041:Aeryth RS15305
gene id: 2041:Aeryth_RS15305
uniprot id: A0A0U4DD03
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

2041:Aeryth RS12610
gene id: 2041:Aeryth_RS12610
uniprot id: A0A0U4CJG4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the MshB deacetylase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deacetylation of 1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway.

2041:Aeryth RS08400
gene id: 2041:Aeryth_RS08400
uniprot id: A0A0U4B9X8
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Feedback inhibited by histidine.

2041:Aeryth RS13650
gene id: 2041:Aeryth_RS13650
uniprot id: A0A0U4BD85
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

2041:Aeryth RS07660
gene id: 2041:Aeryth_RS07660
uniprot id: A0A0U4D8T7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

2041:Aeryth RS11900
gene id: 2041:Aeryth_RS11900
uniprot id: A0A0U3T3Y7
names: Similarity
messages: Belongs to the Fur family.

2041:Aeryth RS18505
gene id: 2041:Aeryth_RS18505
uniprot id: A0A0U4B870
names: Similarity
messages: Belongs to the transglycosylase family. Rpf subfamily.

2041:Aeryth RS06705
gene id: 2041:Aeryth_RS06705
uniprot id: A0A0U4BGJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

2041:Aeryth RS07290
gene id: 2041:Aeryth_RS07290
uniprot id: A0A0U4CUP9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

2041:Aeryth RS07860
gene id: 2041:Aeryth_RS07860
uniprot id: A0A0U3TGA4
names: Subcellular Location Annotation
messages: Membrane

2041:Aeryth RS02815
gene id: 2041:Aeryth_RS02815
uniprot id: A0A0U3SYS1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

2041:Aeryth RS16085
gene id: 2041:Aeryth_RS16085
uniprot id: A0A0U4C575
names: Similarity
messages: Belongs to the myo-inositol 1-phosphate synthase family.

2041:Aeryth RS00040
gene id: 2041:Aeryth_RS00040
uniprot id: A0A0U4BCT3
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

2041:Aeryth RS13615
gene id: 2041:Aeryth_RS13615
uniprot id: A0A0U4CYA0
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

2041:Aeryth RS00090
gene id: 2041:Aeryth_RS00090
uniprot id: A0A0U4B568
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Membrane

2041:Aeryth RS06885
gene id: 2041:Aeryth_RS06885
uniprot id: A0A0U3KHJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

2041:Aeryth RS02335
gene id: 2041:Aeryth_RS02335
uniprot id: A0A0U4D5X5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NlpA lipoprotein family.
messages: Membrane

2041:Aeryth RS13495
gene id: 2041:Aeryth_RS13495
uniprot id: A0A0U4CR95
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

2041:Aeryth RS03825
gene id: 2041:Aeryth_RS03825
uniprot id: A0A0U4CEK4
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2041:Aeryth RS03695
gene id: 2041:Aeryth_RS03695
uniprot id: A0A0U3SZ79
names: Similarity
messages: Belongs to the GARS family.

2041:Aeryth RS06415
gene id: 2041:Aeryth_RS06415
uniprot id: A0A0U4CU73
names: Similarity
messages: Belongs to the prokaryotic/mitochondrial release factor family.

2041:Aeryth RS03800
gene id: 2041:Aeryth_RS03800
uniprot id: A0A0U4AU28
names: Subcellular Location Annotation
messages: Membrane

2041:Aeryth RS10285
gene id: 2041:Aeryth_RS10285
uniprot id: A0A0U4BBA2
names: Subcellular Location Annotation
messages: Membrane

2041:Aeryth RS13620
gene id: 2041:Aeryth_RS13620
uniprot id: A0A0U4CCQ8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

2041:Aeryth RS14595
gene id: 2041:Aeryth_RS14595
uniprot id: A0A0U4C4E5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Membrane

2041:Aeryth RS08675
gene id: 2041:Aeryth_RS08675
uniprot id: A0A0U4CVL9
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

2041:Aeryth RS14580
gene id: 2041:Aeryth_RS14580
uniprot id: A0A0U4CT54
names: Function
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.

2041:Aeryth RS12270
gene id: 2041:Aeryth_RS12270
uniprot id: A0A0U3T3X9
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

2041:Aeryth RS08470
gene id: 2041:Aeryth_RS08470
uniprot id: A0A0U4CNS1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

2041:Aeryth RS09640
gene id: 2041:Aeryth_RS09640
uniprot id: A0A0U4AX73
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

2041:Aeryth RS02655
gene id: 2041:Aeryth_RS02655
uniprot id: A0A0U4ATA7
names: Subcellular Location Annotation
messages: Membrane

2041:Aeryth RS09745
gene id: 2041:Aeryth_RS09745
uniprot id: A0A0U4BB09
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

2041:Aeryth RS16115
gene id: 2041:Aeryth_RS16115
uniprot id: A0A0U4CLA2
names: Similarity
messages: Belongs to the disproportionating enzyme family.

2041:Aeryth RS11485
gene id: 2041:Aeryth_RS11485
uniprot id: A0A0U4CRQ8
names: Similarity
names: Subunit
messages: Belongs to the aldehyde dehydrogenase family.
messages: Homotetramer.

2041:Aeryth RS13415
gene id: 2041:Aeryth_RS13415
uniprot id: A0A0U3T4S0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2041:Aeryth RS13210
gene id: 2041:Aeryth_RS13210
uniprot id: Q6I860
names: Subunit
messages: Heterodimer of an alpha and a beta chain.

2041:Aeryth RS14385
gene id: 2041:Aeryth_RS14385
uniprot id: A0A0U4CRR2
names: Similarity
messages: Belongs to the Rv1128c/1148c/1588c/1702c/1945/3466 family.

2041:Aeryth RS11845
gene id: 2041:Aeryth_RS11845
uniprot id: A0A0U4C300
names: Subcellular Location Annotation
messages: Membrane

2041:Aeryth RS07330
gene id: 2041:Aeryth_RS07330
uniprot id: A0A0U4CGL2
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

2041:Aeryth RS08985
gene id: 2041:Aeryth_RS08985
uniprot id: A0A0U3T2D8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM61 family.
messages: Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA.
messages: Homotetramer composed of a dimer of dimers.

2041:Aeryth RS03775
gene id: 2041:Aeryth_RS03775
uniprot id: A0A0U3SZ97
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial microcompartment
messages: Belongs to the EutC family.
messages: Binds between the large and small subunits.
messages: Catalyzes the deamination of various vicinal amino-alcohols to oxo compounds. Allows this organism to utilize ethanolamine as the sole source of nitrogen and carbon in the presence of external vitamin B12.
messages: The basic unit is a heterodimer which dimerizes to form tetramers. The heterotetramers trimerize; 6 large subunits form a core ring with 6 small subunits projecting outwards.

2041:Aeryth RS13975
gene id: 2041:Aeryth_RS13975
uniprot id: A0A0U4CYH5
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

2041:Aeryth RS17075
gene id: 2041:Aeryth_RS17075
uniprot id: A0A0U4CLR3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

2041:Aeryth RS02215
gene id: 2041:Aeryth_RS02215
uniprot id: A0A0U3SYF7
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

2041:Aeryth RS08965
gene id: 2041:Aeryth_RS08965
uniprot id: A0A0U4BAK5
names: Similarity
messages: Belongs to the Pup ligase/Pup deamidase family. Pup deamidase subfamily.

2041:Aeryth RS12505
gene id: 2041:Aeryth_RS12505
uniprot id: A0A0U4DBE4
names: Similarity
messages: Belongs to the type IB topoisomerase family.

2041:Aeryth RS05580
gene id: 2041:Aeryth_RS05580
uniprot id: A0A0U4BFX6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Could methylate the ribose at the nucleotide 34 wobble position in tRNA.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2041:Aeryth RS08130
gene id: 2041:Aeryth_RS08130
uniprot id: A0A0U3TGF7
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

2041:Aeryth RS00145
gene id: 2041:Aeryth_RS00145
uniprot id: A0A0U4B5P9
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

2041:Aeryth RS00505
gene id: 2041:Aeryth_RS00505
uniprot id: A0A0U4CJC1
names: Function
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: May catalyze the transamination reaction in phenylalanine biosynthesis.

2041:Aeryth RS17070
gene id: 2041:Aeryth_RS17070
uniprot id: A0A0U4BFB1
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

2041:Aeryth RS08455
gene id: 2041:Aeryth_RS08455
uniprot id: A0A0U3KIP6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

2041:Aeryth RS11315
gene id: 2041:Aeryth_RS11315
uniprot id: A0A0U4AY29
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

2041:Aeryth RS16780
gene id: 2041:Aeryth_RS16780
uniprot id: A0A0U4CEL6
names: Similarity
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

2041:Aeryth RS01980
gene id: 2041:Aeryth_RS01980
uniprot id: A0A0U4BXF4
names: Similarity
messages: Belongs to the glutamate synthase family.

2041:Aeryth RS10495
gene id: 2041:Aeryth_RS10495
uniprot id: A0A0U4BB34
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

2041:Aeryth RS11535
gene id: 2041:Aeryth_RS11535
uniprot id: A0A0U4CIT0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

2041:Aeryth RS00020
gene id: 2041:Aeryth_RS00020
uniprot id: A0A0U4CQT2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

2041:Aeryth RS10520
gene id: 2041:Aeryth_RS10520
uniprot id: A0A0U4CWJ7
names: Similarity
messages: Belongs to the YggT family.

2041:Aeryth RS10575
gene id: 2041:Aeryth_RS10575
uniprot id: A0A0U3T375
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

2041:Aeryth RS05125
gene id: 2041:Aeryth_RS05125
uniprot id: A0A0U4AUS2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

2041:Aeryth RS09570
gene id: 2041:Aeryth_RS09570
uniprot id: A0A0U4D9T9
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the xylose isomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2041:Aeryth RS16460
gene id: 2041:Aeryth_RS16460
uniprot id: A0A0U4DDK9
names: Similarity
messages: Belongs to the peptidase S1B family.

2041:Aeryth RS09890
gene id: 2041:Aeryth_RS09890
uniprot id: A0A0U4AXB4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PdxS/SNZ family.
messages: Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
messages: In the presence of PdxT, forms a dodecamer of heterodimers.

2041:Aeryth RS10335
gene id: 2041:Aeryth_RS10335
uniprot id: A0A0U4CWG5
names: Subcellular Location Annotation
messages: Membrane

2041:Aeryth RS11275
gene id: 2041:Aeryth_RS11275
uniprot id: A0A0U3T3M7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

2041:Aeryth RS08540
gene id: 2041:Aeryth_RS08540
uniprot id: A0A0U4BAC3
names: Similarity
messages: Belongs to the HSP15 family.

2041:Aeryth RS12760
gene id: 2041:Aeryth_RS12760
uniprot id: A0A0U4BK19
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

2041:Aeryth RS02890
gene id: 2041:Aeryth_RS02890
uniprot id: A0A0U3SYY0
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

2041:Aeryth RS15425
gene id: 2041:Aeryth_RS15425
uniprot id: A0A0U4CS90
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic Ku family.
messages: Homodimer. Interacts with LigD.
messages: With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD.

2041:Aeryth RS06945
gene id: 2041:Aeryth_RS06945
uniprot id: A0A0U4C9B9
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.

2041:Aeryth RS03325
gene id: 2041:Aeryth_RS03325
uniprot id: A0A0U4CM51
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

2041:Aeryth RS15825
gene id: 2041:Aeryth_RS15825
uniprot id: Q5Y9I0
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

2041:Aeryth RS00625
gene id: 2041:Aeryth_RS00625
uniprot id: A0A0U4C5X1
names: Subcellular Location Annotation
messages: Membrane

2041:Aeryth RS09440
gene id: 2041:Aeryth_RS09440
uniprot id: A0A0U4CA78
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gluconeogenesis factor family.
messages: Cytoplasm
messages: Required for morphogenesis under gluconeogenic growth conditions.

2041:Aeryth RS04950
gene id: 2041:Aeryth_RS04950
uniprot id: A0A0U4C8C6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

2041:Aeryth RS10455
gene id: 2041:Aeryth_RS10455
uniprot id: A0A0U4DAB0
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

2041:Aeryth RS14640
gene id: 2041:Aeryth_RS14640
uniprot id: A0A0U3TJV3
names: Subcellular Location Annotation
messages: Membrane

2041:Aeryth RS09405
gene id: 2041:Aeryth_RS09405
uniprot id: A0A0U4BAT8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase-binding protein RbpA family.
messages: Bind 1 Zn(2+) per subunit.
messages: Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters.
messages: Forms a complex with the RNAP catalytic core and with free principal sigma factors.

2041:Aeryth RS03280
gene id: 2041:Aeryth_RS03280
uniprot id: A0A0U4B7F3
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.

2041:Aeryth RS10470
gene id: 2041:Aeryth_RS10470
uniprot id: A0A0U4BBD6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

2041:Aeryth RS08325
gene id: 2041:Aeryth_RS08325
uniprot id: A0A0U3T1R3
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

2041:Aeryth RS07055
gene id: 2041:Aeryth_RS07055
uniprot id: A0A0U3KHP5
names: Function
messages: Catalyzes the phosphorylation of hydroxymethylpyrimidine phosphate (HMP-P) to HMP-PP, and of HMP to HMP-P.

2041:Aeryth RS14930
gene id: 2041:Aeryth_RS14930
uniprot id: A0A0U4C4L4
names: Function
messages: Acyltransferase required for the direct transfer of medium- to long-chain fatty acyl moieties from a carrier protein (MbtL) on to the epsilon-amino group of lysine residue in the mycobactin core.

2041:Aeryth RS03730
gene id: 2041:Aeryth_RS03730
uniprot id: A0A0U4BEU0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

2041:Aeryth RS10350
gene id: 2041:Aeryth_RS10350
uniprot id: A0A0U4AXK5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

2041:Aeryth RS15870
gene id: 2041:Aeryth_RS15870
uniprot id: Q5Y9H1
names: Similarity
messages: Belongs to the thioesterase family.

2041:Aeryth RS06675
gene id: 2041:Aeryth_RS06675
uniprot id: A0A0U4C881
names: Subcellular Location Annotation
messages: Membrane

2041:Aeryth RS07355
gene id: 2041:Aeryth_RS07355
uniprot id: A0A0U3T174
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

2041:Aeryth RS04305
gene id: 2041:Aeryth_RS04305
uniprot id: A0A0U4B7I9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

2041:Aeryth RS04985
gene id: 2041:Aeryth_RS04985
uniprot id: A0A0U4CF52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

2041:Aeryth RS03500
gene id: 2041:Aeryth_RS03500
uniprot id: A0A0U3SZ53
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.

2041:Aeryth RS03965
gene id: 2041:Aeryth_RS03965
uniprot id: A0A0U4CSV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic sulfate-binding protein family.
messages: Periplasm

2041:Aeryth RS06485
gene id: 2041:Aeryth_RS06485
uniprot id: A0A0U3T0U7
names: Similarity
messages: Belongs to the TPP enzyme family.

2041:Aeryth RS13420
gene id: 2041:Aeryth_RS13420
uniprot id: A0A0U4BCL6
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

2041:Aeryth RS04250
gene id: 2041:Aeryth_RS04250
uniprot id: A0A0U4BYN7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

2041:Aeryth RS03115
gene id: 2041:Aeryth_RS03115
uniprot id: A0A0U4B7B7
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

2041:Aeryth RS02195
gene id: 2041:Aeryth_RS02195
uniprot id: A0A0U3TDG4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

2041:Aeryth RS10445
gene id: 2041:Aeryth_RS10445
uniprot id: A0A0U4AXM2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

2041:Aeryth RS13765
gene id: 2041:Aeryth_RS13765
uniprot id: A0A0U3T4Q6
names: Cofactor
names: Similarity
messages: Belongs to the 4HPPD family.
messages: Binds 1 Fe cation per subunit.

2041:Aeryth RS09665
gene id: 2041:Aeryth_RS09665
uniprot id: A0A0U4CHT7
names: Similarity
messages: Belongs to the Rv1128c/1148c/1588c/1702c/1945/3466 family.

2041:Aeryth RS03195
gene id: 2041:Aeryth_RS03195
uniprot id: A0A0U3KFJ2
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

2041:Aeryth RS12235
gene id: 2041:Aeryth_RS12235
uniprot id: A0A0U4BCF2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

2041:Aeryth RS05590
gene id: 2041:Aeryth_RS05590
uniprot id: A0A0U3KGS2
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

2041:Aeryth RS05285
gene id: 2041:Aeryth_RS05285
uniprot id: A0A0U4CN81
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

2041:Aeryth RS11635
gene id: 2041:Aeryth_RS11635
uniprot id: A0A0U3TIB7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

2041:Aeryth RS14650
gene id: 2041:Aeryth_RS14650
uniprot id: A0A0U4BDF0
names: Similarity
messages: Belongs to the CobH/CbiC family.

2041:Aeryth RS02000
gene id: 2041:Aeryth_RS02000
uniprot id: A0A0U3KEX4
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

2041:Aeryth RS11280
gene id: 2041:Aeryth_RS11280
uniprot id: A0A0U4BBI5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

2041:Aeryth RS00260
gene id: 2041:Aeryth_RS00260
uniprot id: A0A0U4C522
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MetX family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

2041:Aeryth RS03935
gene id: 2041:Aeryth_RS03935
uniprot id: A0A0U3SZI8
names: Subcellular Location Annotation
messages: Membrane

2041:Aeryth RS04000
gene id: 2041:Aeryth_RS04000
uniprot id: A0A0U4B7T7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2041:Aeryth RS15270
gene id: 2041:Aeryth_RS15270
uniprot id: A0A0U4CDL4
names: Similarity
messages: Belongs to the ribulokinase family.

2041:Aeryth RS14030
gene id: 2041:Aeryth_RS14030
uniprot id: A0A0U4CRI4
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. Fucose synthase subfamily.
messages: Catalyzes the two-step NADP-dependent conversion of GDP-4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction.

2041:Aeryth RS10920
gene id: 2041:Aeryth_RS10920
uniprot id: A0A0U3T323
names: Similarity
messages: Belongs to the peptidase S8 family.

2041:Aeryth RS15515
gene id: 2041:Aeryth_RS15515
uniprot id: A0A0U3T5X8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

2041:Aeryth RS03525
gene id: 2041:Aeryth_RS03525
uniprot id: A0A0U4C7B6
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

2041:Aeryth RS04090
gene id: 2041:Aeryth_RS04090
uniprot id: A0A0U4CEP6
names: Similarity
names: Subunit
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
messages: Homodimer.

2041:Aeryth RS00565
gene id: 2041:Aeryth_RS00565
uniprot id: A0A0U4D510
names: Subunit
messages: Homotetramer.

2041:Aeryth RS02170
gene id: 2041:Aeryth_RS02170
uniprot id: A0A0U4D5U6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

2041:Aeryth RS02260
gene id: 2041:Aeryth_RS02260
uniprot id: A0A0U3KF17
names: Function
names: Similarity
messages: Belongs to the trehalose phosphatase family.
messages: Removes the phosphate from trehalose 6-phosphate to produce free trehalose.

2041:Aeryth RS03955
gene id: 2041:Aeryth_RS03955
uniprot id: A0A0U4C6W0
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

2041:Aeryth RS02080
gene id: 2041:Aeryth_RS02080
uniprot id: A0A0U4D5S7
names: Similarity
messages: Belongs to the peptidase C40 family.

2041:Aeryth RS13595
gene id: 2041:Aeryth_RS13595
uniprot id: A0A0U4BCQ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

2041:Aeryth RS13325
gene id: 2041:Aeryth_RS13325
uniprot id: A0A0U3TJ71
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

2041:Aeryth RS03170
gene id: 2041:Aeryth_RS03170
uniprot id: A0A0U4C749
names: Subcellular Location Annotation
messages: Membrane

2041:Aeryth RS06970
gene id: 2041:Aeryth_RS06970
uniprot id: A0A0U3KHM7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.
messages: Homotetramer.
messages: Uses inorganic polyphosphate (polyP) as a donor to convert GDP to GTP or ADP to ATP.

2041:Aeryth RS08605
gene id: 2041:Aeryth_RS08605
uniprot id: A0A0U4C193
names: Similarity
messages: Belongs to the UPF0749 family.

2041:Aeryth RS11390
gene id: 2041:Aeryth_RS11390
uniprot id: A0A0U4CX31
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

2041:Aeryth RS02290
gene id: 2041:Aeryth_RS02290
uniprot id: A0A0U4B6D7
names: Subcellular Location Annotation
messages: Cytoplasm

2041:Aeryth RS01700
gene id: 2041:Aeryth_RS01700
uniprot id: A0A0U4C5S7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

2041:Aeryth RS01965
gene id: 2041:Aeryth_RS01965
uniprot id: A0A0U4CLH9
names: Similarity
messages: Belongs to the glutamine synthetase family.

2041:Aeryth RS16355
gene id: 2041:Aeryth_RS16355
uniprot id: A0A0U4BM59
names: Similarity
messages: Belongs to the peptidase C56 family.

2041:Aeryth RS12280
gene id: 2041:Aeryth_RS12280
uniprot id: A0A0U4CS16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

2041:Aeryth RS12070
gene id: 2041:Aeryth_RS12070
uniprot id: A0A0U4BCA6
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

2041:Aeryth RS06125
gene id: 2041:Aeryth_RS06125
uniprot id: A0A0U4CU20
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

2041:Aeryth RS08880
gene id: 2041:Aeryth_RS08880
uniprot id: A0A0U4CHE8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell membrane
messages: Membrane

2041:Aeryth RS09410
gene id: 2041:Aeryth_RS09410
uniprot id: A0A0U4CHP5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

2041:Aeryth RS07670
gene id: 2041:Aeryth_RS07670
uniprot id: A0A0U4B9S7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

2041:Aeryth RS16685
gene id: 2041:Aeryth_RS16685
uniprot id: A0A0U3T6C5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

2041:Aeryth RS14900
gene id: 2041:Aeryth_RS14900
uniprot id: A0A0U3T5C2
names: Similarity
messages: Belongs to the cytochrome P450 family.

2041:Aeryth RS11290
gene id: 2041:Aeryth_RS11290
uniprot id: A0A0U4CB61
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

2041:Aeryth RS02905
gene id: 2041:Aeryth_RS02905
uniprot id: A0A0U4C6C4
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

2041:Aeryth RS14725
gene id: 2041:Aeryth_RS14725
uniprot id: A0A0U3T5F9
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

2041:Aeryth RS16955
gene id: 2041:Aeryth_RS16955
uniprot id: A0A0U4D0A4
names: Similarity
messages: Belongs to the DyP-type peroxidase family.

2041:Aeryth RS12940
gene id: 2041:Aeryth_RS12940
uniprot id: A0A0U4DBM1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

2041:Aeryth RS09270
gene id: 2041:Aeryth_RS09270
uniprot id: A0A0U3T273
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

2041:Aeryth RS16925
gene id: 2041:Aeryth_RS16925
uniprot id: A0A0U3T6Q0
names: Similarity
messages: Belongs to the CsoR family.

2041:Aeryth RS07050
gene id: 2041:Aeryth_RS07050
uniprot id: A0A0U4D8H4
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2041:Aeryth RS06270
gene id: 2041:Aeryth_RS06270
uniprot id: A0A0U4B907
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

2041:Aeryth RS06235
gene id: 2041:Aeryth_RS06235
uniprot id: A0A0U4CU40
names: Subcellular Location Annotation
messages: Membrane

2041:Aeryth RS09495
gene id: 2041:Aeryth_RS09495
uniprot id: A0A0U4CP83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

2041:Aeryth RS15435
gene id: 2041:Aeryth_RS15435
uniprot id: A0A0U3T5W1
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2041:Aeryth RS09955
gene id: 2041:Aeryth_RS09955
uniprot id: A0A0U4CW99
names: Similarity
messages: Belongs to the FAD-binding monooxygenase family.

2041:Aeryth RS13570
gene id: 2041:Aeryth_RS13570
uniprot id: A0A0U4BD62
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

2041:Aeryth RS06930
gene id: 2041:Aeryth_RS06930
uniprot id: A0A0U4C8G3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 3 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

2041:Aeryth RS14805
gene id: 2041:Aeryth_RS14805
uniprot id: A0A0U3T5I0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM86 family.
messages: Membrane

2041:Aeryth RS13445
gene id: 2041:Aeryth_RS13445
uniprot id: A0A0U4CY62
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

2041:Aeryth RS11575
gene id: 2041:Aeryth_RS11575
uniprot id: A0A0U4CRR6
names: Subcellular Location Annotation
messages: Membrane

2041:Aeryth RS13560
gene id: 2041:Aeryth_RS13560
uniprot id: A0A0U4DBY7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

2041:Aeryth RS01750
gene id: 2041:Aeryth_RS01750
uniprot id: A0A0U4CDK3
names: Function
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

2041:Aeryth RS13625
gene id: 2041:Aeryth_RS13625
uniprot id: A0A0U4C3X6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

2041:Aeryth RS16490
gene id: 2041:Aeryth_RS16490
uniprot id: A0A0U3TL13
names: Subcellular Location Annotation
messages: Membrane

2041:Aeryth RS11770
gene id: 2041:Aeryth_RS11770
uniprot id: A0A0U4BJF1
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

2041:Aeryth RS07045
gene id: 2041:Aeryth_RS07045
uniprot id: A0A0U4BGR6
names: Function
names: Similarity
messages: Belongs to the Thz kinase family.
messages: Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).

2041:Aeryth RS15395
gene id: 2041:Aeryth_RS15395
uniprot id: A0A0U4BLK7
names: Caution
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
messages: Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2041:Aeryth RS09445
gene id: 2041:Aeryth_RS09445
uniprot id: A0A0U4CQK5
names: Function
names: Similarity
messages: Belongs to the RapZ-like family.
messages: Displays ATPase and GTPase activities.

2041:Aeryth RS12145
gene id: 2041:Aeryth_RS12145
uniprot id: A0A0U4DB86
names: Similarity
messages: Belongs to the hyi family.

2041:Aeryth RS13410
gene id: 2041:Aeryth_RS13410
uniprot id: A0A0U3TJ84
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

2041:Aeryth RS09140
gene id: 2041:Aeryth_RS09140
uniprot id: A0A0U4D9K9
names: Subcellular Location Annotation
messages: Membrane

2041:Aeryth RS07890
gene id: 2041:Aeryth_RS07890
uniprot id: A0A0U4CPR4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

2041:Aeryth RS15885
gene id: 2041:Aeryth_RS15885
uniprot id: Q5Y9G8
names: Similarity
messages: Belongs to the glycosyltransferase 28 family.

2041:Aeryth RS00630
gene id: 2041:Aeryth_RS00630
uniprot id: A0A0U4BWN7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

2041:Aeryth RS13200
gene id: 2041:Aeryth_RS13200
uniprot id: Q6I859
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

2041:Aeryth RS07335
gene id: 2041:Aeryth_RS07335
uniprot id: A0A0U4CN34
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

2041:Aeryth RS08425
gene id: 2041:Aeryth_RS08425
uniprot id: A0A0U4CVH2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

2041:Aeryth RS13215
gene id: 2041:Aeryth_RS13215
uniprot id: A0A0U4BCZ0
names: Subunit
messages: Heterodimer of an alpha and a beta chain.

2041:Aeryth RS05725
gene id: 2041:Aeryth_RS05725
uniprot id: A0A0U4C7T2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

2041:Aeryth RS06655
gene id: 2041:Aeryth_RS06655
uniprot id: A0A0U3T0Y2
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

2041:Aeryth RS09390
gene id: 2041:Aeryth_RS09390
uniprot id: A0A0U4BI57
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2041:Aeryth RS01795
gene id: 2041:Aeryth_RS01795
uniprot id: A0A0U4C6G3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

2041:Aeryth RS16745
gene id: 2041:Aeryth_RS16745
uniprot id: A0A0U4BF22
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

2041:Aeryth RS06940
gene id: 2041:Aeryth_RS06940
uniprot id: A0A0U4CUH7
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

2041:Aeryth RS12245
gene id: 2041:Aeryth_RS12245
uniprot id: A0A0U4CQQ3
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

2041:Aeryth RS04670
gene id: 2041:Aeryth_RS04670
uniprot id: A0A0U3SZS0
names: Subcellular Location Annotation
messages: Membrane

2041:Aeryth RS18330
gene id: 2041:Aeryth_RS18330
uniprot id: A0A0U4BJB4
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

2041:Aeryth RS00885
gene id: 2041:Aeryth_RS00885
uniprot id: A0A0U4CKX7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

2041:Aeryth RS10175
gene id: 2041:Aeryth_RS10175
uniprot id: A0A0U4BIK4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.
messages: Cell membrane
messages: Involved in the import of queuosine (Q) precursors, required for Q precursor salvage.

2041:Aeryth RS12735
gene id: 2041:Aeryth_RS12735
uniprot id: A0A0U4CS96
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

2041:Aeryth RS05565
gene id: 2041:Aeryth_RS05565
uniprot id: A0A0U4C8N1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

2041:Aeryth RS13660
gene id: 2041:Aeryth_RS13660
uniprot id: A0A0U4CRC6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

2041:Aeryth RS14095
gene id: 2041:Aeryth_RS14095
uniprot id: A0A0U4AZK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

2041:Aeryth RS02600
gene id: 2041:Aeryth_RS02600
uniprot id: A0A0U4CDZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

2041:Aeryth RS13695
gene id: 2041:Aeryth_RS13695
uniprot id: A0A0U4CYB9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

2041:Aeryth RS02275
gene id: 2041:Aeryth_RS02275
uniprot id: A0A0U4CK85
names: Function
names: Similarity
messages: Belongs to the threonine synthase family.
messages: Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.

2041:Aeryth RS13520
gene id: 2041:Aeryth_RS13520
uniprot id: A0A0U4CCM6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

2041:Aeryth RS11405
gene id: 2041:Aeryth_RS11405
uniprot id: A0A0U4C2S8
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

2041:Aeryth RS07970
gene id: 2041:Aeryth_RS07970
uniprot id: A0A0U3T1I5
names: Similarity
messages: Belongs to the peptidase S8 family.

2041:Aeryth RS15025
gene id: 2041:Aeryth_RS15025
uniprot id: A0A0U4BLD3
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

2041:Aeryth RS17035
gene id: 2041:Aeryth_RS17035
uniprot id: A0A0U4D0C8
names: Subcellular Location Annotation
messages: Membrane

2041:Aeryth RS12925
gene id: 2041:Aeryth_RS12925
uniprot id: A0A0U4C3J2
names: Subcellular Location Annotation
messages: Membrane

2041:Aeryth RS00930
gene id: 2041:Aeryth_RS00930
uniprot id: A0A0U4B647
names: Function
names: Similarity
messages: Belongs to the TrhO family.
messages: Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.

2041:Aeryth RS02925
gene id: 2041:Aeryth_RS02925
uniprot id: A0A0U4BXW9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

2041:Aeryth RS15335
gene id: 2041:Aeryth_RS15335
uniprot id: A0A0U3T5T7
names: Subcellular Location Annotation
messages: Membrane

2041:Aeryth RS14700
gene id: 2041:Aeryth_RS14700
uniprot id: A0A0U3KMF8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

2041:Aeryth RS07990
gene id: 2041:Aeryth_RS07990
uniprot id: A0A0U4CV52
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA.
messages: Belongs to the helicase family. UvrD subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding. Interacts with RecA.
messages: The C-terminal domain has nuclease activity and interacts with RecD. It interacts with RecA, facilitating its loading onto ssDNA.
messages: The N-terminal DNA-binding domain is a ssDNA-dependent ATPase and has ATP-dependent 3'-5' helicase function. This domain interacts with RecC.

2041:Aeryth RS09930
gene id: 2041:Aeryth_RS09930
uniprot id: A0A0U3T2V9
names: Subcellular Location Annotation
messages: Membrane

2041:Aeryth RS18480
gene id: 2041:Aeryth_RS18480
uniprot id: A0A0U4DBQ7
names: Subcellular Location Annotation
messages: Membrane

2041:Aeryth RS01410
gene id: 2041:Aeryth_RS01410
uniprot id: A0A0U3SY30
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

2041:Aeryth RS14605
gene id: 2041:Aeryth_RS14605
uniprot id: A0A0U4AZW1
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

2041:Aeryth RS04285
gene id: 2041:Aeryth_RS04285
uniprot id: A0A0U4CES4
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

2041:Aeryth RS02185
gene id: 2041:Aeryth_RS02185
uniprot id: A0A0U4CDP6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

2041:Aeryth RS06650
gene id: 2041:Aeryth_RS06650
uniprot id: A0A0U3TFM3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

2041:Aeryth RS09305
gene id: 2041:Aeryth_RS09305
uniprot id: A0A0U4AX07
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

2041:Aeryth RS02805
gene id: 2041:Aeryth_RS02805
uniprot id: A0A0U3SYW6
names: Subcellular Location Annotation
messages: Membrane

2041:Aeryth RS15835
gene id: 2041:Aeryth_RS15835
uniprot id: Q5Y9H8
names: Similarity
messages: Belongs to the thioesterase family.

2041:Aeryth RS17200
gene id: 2041:Aeryth_RS17200
uniprot id: A0A0U4D0J0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

2041:Aeryth RS08055
gene id: 2041:Aeryth_RS08055
uniprot id: A0A0U4B9P1
names: Similarity
messages: Belongs to the AB hydrolase superfamily. Lipase family.

2041:Aeryth RS03805
gene id: 2041:Aeryth_RS03805
uniprot id: A0A0U4BEV6
names: Subcellular Location Annotation
messages: Membrane

2041:Aeryth RS12575
gene id: 2041:Aeryth_RS12575
uniprot id: A0A0U4C3D2
names: Similarity
messages: Belongs to the citrate synthase family.

2041:Aeryth RS07400
gene id: 2041:Aeryth_RS07400
uniprot id: A0A0U4D8N6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

2041:Aeryth RS07085
gene id: 2041:Aeryth_RS07085
uniprot id: A0A0U4B941
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

2041:Aeryth RS08935
gene id: 2041:Aeryth_RS08935
uniprot id: A0A0U4C1H0
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the Pup ligase/Pup deamidase family. Pup-conjugating enzyme subfamily.
messages: Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine.
messages: The reaction mechanism probably proceeds via the activation of Pup by phosphorylation of its C-terminal glutamate, which is then subject to nucleophilic attack by the substrate lysine, resulting in an isopeptide bond and the release of phosphate as a good leaving group.

2041:Aeryth RS00215
gene id: 2041:Aeryth_RS00215
uniprot id: A0A0U4D4X2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SURF1 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2041:Aeryth RS14360
gene id: 2041:Aeryth_RS14360
uniprot id: A0A0U4DCE1
names: Similarity
messages: Belongs to the PhoU family.
messages: Belongs to the UPF0111 family.

2041:Aeryth RS09935
gene id: 2041:Aeryth_RS09935
uniprot id: A0A0U4BAU4
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

2041:Aeryth RS03530
gene id: 2041:Aeryth_RS03530
uniprot id: A0A0U4BY92
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

2041:Aeryth RS13705
gene id: 2041:Aeryth_RS13705
uniprot id: A0A0U4C3Z4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

2041:Aeryth RS06500
gene id: 2041:Aeryth_RS06500
uniprot id: A0A0U3T0R2
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

2041:Aeryth RS16525
gene id: 2041:Aeryth_RS16525
uniprot id: A0A0U4CE83
names: Similarity
messages: Belongs to the carotenoid/retinoid oxidoreductase family.

2041:Aeryth RS11685
gene id: 2041:Aeryth_RS11685
uniprot id: A0A0U4BJD5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2041:Aeryth RS06550
gene id: 2041:Aeryth_RS06550
uniprot id: A0A0U4B962
names: Similarity
names: Subunit
messages: Belongs to the glutaminase family.
messages: Homotetramer.

2041:Aeryth RS03670
gene id: 2041:Aeryth_RS03670
uniprot id: A0A0U4CEH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the iron-containing alcohol dehydrogenase family. Hydroxyacid-oxoacid transhydrogenase subfamily.
messages: Mitochondrion

2041:Aeryth RS12315
gene id: 2041:Aeryth_RS12315
uniprot id: A0A0U3KL11
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

2041:Aeryth RS03690
gene id: 2041:Aeryth_RS03690
uniprot id: A0A0U4B777
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

2041:Aeryth RS06690
gene id: 2041:Aeryth_RS06690
uniprot id: A0A0U4C972
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

2041:Aeryth RS17165
gene id: 2041:Aeryth_RS17165
uniprot id: A0A0U4CT77
names: Similarity
messages: Belongs to the thioredoxin family.

2041:Aeryth RS13425
gene id: 2041:Aeryth_RS13425
uniprot id: A0A0U3T4I5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic pantothenate kinase family.
messages: Cytoplasm

2041:Aeryth RS02075
gene id: 2041:Aeryth_RS02075
uniprot id: A0A0U4BDV5
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Phosphotriesterase family.
messages: Binds 2 divalent metal cations per subunit.

2041:Aeryth RS09710
gene id: 2041:Aeryth_RS09710
uniprot id: A0A0U4CAX1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2041:Aeryth RS06640
gene id: 2041:Aeryth_RS06640
uniprot id: A0A0U4CG35
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2041:Aeryth RS08715
gene id: 2041:Aeryth_RS08715
uniprot id: A0A0U4BAF2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PAPS reductase family. CysD subfamily.
messages: Heterodimer composed of CysD, the smaller subunit, and CysN.
messages: With CysN forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.

2041:Aeryth RS10170
gene id: 2041:Aeryth_RS10170
uniprot id: A0A0U4AXG9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2041:Aeryth RS13715
gene id: 2041:Aeryth_RS13715
uniprot id: A0A0U4BKK9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.

2041:Aeryth RS03765
gene id: 2041:Aeryth_RS03765
uniprot id: A0A0U3SZF4
names: Similarity
messages: Belongs to the FPG family.

2041:Aeryth RS01480
gene id: 2041:Aeryth_RS01480
uniprot id: A0A0U4CDC6
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

2041:Aeryth RS14565
gene id: 2041:Aeryth_RS14565
uniprot id: A0A0U4BDC6
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

2041:Aeryth RS04685
gene id: 2041:Aeryth_RS04685
uniprot id: A0A0U4CTA0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Binds 1 Fe(3+) ion per subunit.
messages: Involved in the hydrocarbon hydroxylating system, which transfers electrons from NADH to rubredoxin reductase and then through rubredoxin to alkane 1 monooxygenase.

2041:Aeryth RS04815
gene id: 2041:Aeryth_RS04815
uniprot id: A0A0U4CF21
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

2041:Aeryth RS07650
gene id: 2041:Aeryth_RS07650
uniprot id: A0A0U4AW22
names: Similarity
messages: Belongs to the ribF family.

2041:Aeryth RS06875
gene id: 2041:Aeryth_RS06875
uniprot id: A0A0U4BGM9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Heterodimer of an alpha and a beta subunit.
messages: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

2041:Aeryth RS07805
gene id: 2041:Aeryth_RS07805
uniprot id: A0A0U4CV11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

2041:Aeryth RS14135
gene id: 2041:Aeryth_RS14135
uniprot id: A0A0U3T546
names: Caution
names: Function
names: PTM
names: Similarity
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2041:Aeryth RS14925
gene id: 2041:Aeryth_RS14925
uniprot id: A0A0U4CDF6
names: Similarity
messages: Belongs to the IucA/IucC family.

2041:Aeryth RS08240
gene id: 2041:Aeryth_RS08240
uniprot id: A0A0U4C9E2
names: Similarity
messages: Belongs to the thymidine kinase family.

2041:Aeryth RS18170
gene id: 2041:Aeryth_RS18170
uniprot id: A0A0U4D6V2
names: Subcellular Location Annotation
messages: Membrane

2041:Aeryth RS10745
gene id: 2041:Aeryth_RS10745
uniprot id: A0A0U3T3B1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with subunits I, II and III to form cytochrome c oxidase.
messages: Belongs to the cytochrome c oxidase bacterial subunit CtaF family.
messages: Cell membrane
messages: Membrane
messages: Part of cytochrome c oxidase, its function is unknown.

2041:Aeryth RS07545
gene id: 2041:Aeryth_RS07545
uniprot id: A0A0U4C9L3
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2041:Aeryth RS08015
gene id: 2041:Aeryth_RS08015
uniprot id: A0A0U4D8Z2
names: Similarity
messages: Belongs to the OsmC/Ohr family.

2041:Aeryth RS03285
gene id: 2041:Aeryth_RS03285
uniprot id: A0A0U4CEB9
names: Function
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

2041:Aeryth RS11270
gene id: 2041:Aeryth_RS11270
uniprot id: A0A0U3TI38
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

2041:Aeryth RS02450
gene id: 2041:Aeryth_RS02450
uniprot id: A0A0U3TDL6
names: Similarity
messages: Belongs to the IMPDH/GMPR family.

2041:Aeryth RS04170
gene id: 2041:Aeryth_RS04170
uniprot id: A0A0U3KG15
names: Subcellular Location Annotation
messages: Membrane

2041:Aeryth RS01505
gene id: 2041:Aeryth_RS01505
uniprot id: A0A0U3SY46
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

2041:Aeryth RS02470
gene id: 2041:Aeryth_RS02470
uniprot id: A0A0U4C660
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

2041:Aeryth RS08765
gene id: 2041:Aeryth_RS08765
uniprot id: A0A0U4CAH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

2041:Aeryth RS09550
gene id: 2041:Aeryth_RS09550
uniprot id: A0A0U4CAU0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

2041:Aeryth RS12495
gene id: 2041:Aeryth_RS12495
uniprot id: A0A0U4AYR3
names: Similarity
messages: Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family.

2041:Aeryth RS02180
gene id: 2041:Aeryth_RS02180
uniprot id: A0A0U4B6T5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL31 family.

2041:Aeryth RS08360
gene id: 2041:Aeryth_RS08360
uniprot id: A0A0U4BHL8
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

2041:Aeryth RS17010
gene id: 2041:Aeryth_RS17010
uniprot id: A0A0U3T6S0
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

2041:Aeryth RS15015
gene id: 2041:Aeryth_RS15015
uniprot id: A0A0U4C4N6
names: Subcellular Location Annotation
messages: Membrane

2041:Aeryth RS10965
gene id: 2041:Aeryth_RS10965
uniprot id: A0A0U4DAK7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2041:Aeryth RS08450
gene id: 2041:Aeryth_RS08450
uniprot id: A0A0U4D992
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

2041:Aeryth RS01990
gene id: 2041:Aeryth_RS01990
uniprot id: A0A0U4BDT9
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20 family.
messages: Binds 2 Zn(2+) ions per subunit.

2041:Aeryth RS03005
gene id: 2041:Aeryth_RS03005
uniprot id: A0A0U4C723
names: Similarity
messages: Belongs to the Nth/MutY family.

2041:Aeryth RS08930
gene id: 2041:Aeryth_RS08930
uniprot id: A0A0U4CAK0
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

2041:Aeryth RS02345
gene id: 2041:Aeryth_RS02345
uniprot id: A0A0U4B6W7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2041:Aeryth RS12845
gene id: 2041:Aeryth_RS12845
uniprot id: A0A0U4AYX9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2041:Aeryth RS10570
gene id: 2041:Aeryth_RS10570
uniprot id: A0A0U3THQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

2041:Aeryth RS09920
gene id: 2041:Aeryth_RS09920
uniprot id: A0A0U4CPH1
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2041:Aeryth RS06815
gene id: 2041:Aeryth_RS06815
uniprot id: A0A0U4CMT2
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

2041:Aeryth RS17170
gene id: 2041:Aeryth_RS17170
uniprot id: A0A0U3TLL7
names: Similarity
messages: Belongs to the ParB family.

2041:Aeryth RS00680
gene id: 2041:Aeryth_RS00680
uniprot id: A0A0U3SXT1
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

2041:Aeryth RS08270
gene id: 2041:Aeryth_RS08270
uniprot id: A0A0U4AWF1
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

2041:Aeryth RS10355
gene id: 2041:Aeryth_RS10355
uniprot id: A0A0U4BIN7
names: Similarity
messages: Belongs to the TrpC family.

2041:Aeryth RS02855
gene id: 2041:Aeryth_RS02855
uniprot id: A0A0U4D678
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

2041:Aeryth RS16145
gene id: 2041:Aeryth_RS16145
uniprot id: A0A0U4CE58
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

2041:Aeryth RS13825
gene id: 2041:Aeryth_RS13825
uniprot id: A0A0U4BDB8
names: Similarity
messages: Belongs to the asp23 family.

2041:Aeryth RS16025
gene id: 2041:Aeryth_RS16025
uniprot id: A0A0U4CL85
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.

2041:Aeryth RS11045
gene id: 2041:Aeryth_RS11045
uniprot id: A0A0U4DAM5
names: Similarity
messages: Belongs to the CFA/CMAS family.

2041:Aeryth RS01240
gene id: 2041:Aeryth_RS01240
uniprot id: A0A0U4CL39
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

2041:Aeryth RS14795
gene id: 2041:Aeryth_RS14795
uniprot id: A0A0U3TJZ0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

2041:Aeryth RS05220
gene id: 2041:Aeryth_RS05220
uniprot id: A0A0U4BFM3
names: Similarity
messages: Belongs to the manganese catalase family.

2041:Aeryth RS07385
gene id: 2041:Aeryth_RS07385
uniprot id: A0A0U4AVX3
names: Similarity
messages: Belongs to the UPF0102 family.

2041:Aeryth RS01340
gene id: 2041:Aeryth_RS01340
uniprot id: A0A0U4CRC7
names: Similarity
messages: Belongs to the ComB family.

2041:Aeryth RS02840
gene id: 2041:Aeryth_RS02840
uniprot id: A0A0U4BXU9
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

2041:Aeryth RS10805
gene id: 2041:Aeryth_RS10805
uniprot id: A0A0U4BBJ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

2041:Aeryth RS14150
gene id: 2041:Aeryth_RS14150
uniprot id: A0A0U4CCY6
names: Subcellular Location Annotation
messages: Membrane

2041:Aeryth RS02435
gene id: 2041:Aeryth_RS02435
uniprot id: A0A0U4B6Y3
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

2041:Aeryth RS05915
gene id: 2041:Aeryth_RS05915
uniprot id: A0A0U4AV61
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2041:Aeryth RS00650
gene id: 2041:Aeryth_RS00650
uniprot id: A0A0U4D523
names: Subcellular Location Annotation
messages: Membrane

2041:Aeryth RS13920
gene id: 2041:Aeryth_RS13920
uniprot id: A0A0U4BDD3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

2041:Aeryth RS11435
gene id: 2041:Aeryth_RS11435
uniprot id: A0A0U4DAU3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

2041:Aeryth RS04550
gene id: 2041:Aeryth_RS04550
uniprot id: A0A0U4CEX4
names: Similarity
messages: Belongs to the universal stress protein A family.

2041:Aeryth RS07655
gene id: 2041:Aeryth_RS07655
uniprot id: A0A0U4BH48
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

2041:Aeryth RS07610
gene id: 2041:Aeryth_RS07610
uniprot id: A0A0U3T1I0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

2041:Aeryth RS03655
gene id: 2041:Aeryth_RS03655
uniprot id: A0A0U3KFR5
names: Similarity
messages: Belongs to the Nudix hydrolase family.

2041:Aeryth RS07705
gene id: 2041:Aeryth_RS07705
uniprot id: A0A0U4C949
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

2041:Aeryth RS14990
gene id: 2041:Aeryth_RS14990
uniprot id: A0A0U4CDJ3
names: Similarity
messages: Belongs to the WXG100 family.

2041:Aeryth RS03305
gene id: 2041:Aeryth_RS03305
uniprot id: A0A0U4B701
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

2041:Aeryth RS01715
gene id: 2041:Aeryth_RS01715
uniprot id: A0A0U4C6F0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

2041:Aeryth RS12125
gene id: 2041:Aeryth_RS12125
uniprot id: A0A0U4CC53
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

2041:Aeryth RS08375
gene id: 2041:Aeryth_RS08375
uniprot id: A0A0U4BA87
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

2041:Aeryth RS01805
gene id: 2041:Aeryth_RS01805
uniprot id: A0A0U4ASU1
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

2041:Aeryth RS12120
gene id: 2041:Aeryth_RS12120
uniprot id: A0A0U4CXG7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

2041:Aeryth RS12115
gene id: 2041:Aeryth_RS12115
uniprot id: A0A0U4CRY9
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

2041:Aeryth RS10830
gene id: 2041:Aeryth_RS10830
uniprot id: A0A0U3T3C8
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

2041:Aeryth RS01535
gene id: 2041:Aeryth_RS01535
uniprot id: A0A0U4C6B8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2041:Aeryth RS12285
gene id: 2041:Aeryth_RS12285
uniprot id: A0A0U4CXK4
names: Similarity
messages: Belongs to the prephenate/arogenate dehydrogenase family.

2041:Aeryth RS05490
gene id: 2041:Aeryth_RS05490
uniprot id: A0A0U4AUY7
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

2041:Aeryth RS00235
gene id: 2041:Aeryth_RS00235
uniprot id: A0A0U4CJ78
names: Subcellular Location Annotation
messages: Membrane

2041:Aeryth RS04255
gene id: 2041:Aeryth_RS04255
uniprot id: A0A0U4AUB1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane

2041:Aeryth RS04965
gene id: 2041:Aeryth_RS04965
uniprot id: A0A0U4BFG9
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

2041:Aeryth RS09655
gene id: 2041:Aeryth_RS09655
uniprot id: A0A0U3KJE3
names: Function
names: Similarity
messages: Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
messages: Regulates the transcription of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines.

2041:Aeryth RS00560
gene id: 2041:Aeryth_RS00560
uniprot id: A0A0U4BD44
names: Function
names: Similarity
messages: Belongs to the uricase family.
messages: Catalyzes the oxidation of uric acid to 5-hydroxyisourate, which is further processed to form (S)-allantoin.

2041:Aeryth RS14120
gene id: 2041:Aeryth_RS14120
uniprot id: A0A0U4CK65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

2041:Aeryth RS07595
gene id: 2041:Aeryth_RS07595
uniprot id: A0A0U4CGQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

2041:Aeryth RS03885
gene id: 2041:Aeryth_RS03885
uniprot id: A0A0U4BYG4
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

2041:Aeryth RS16055
gene id: 2041:Aeryth_RS16055
uniprot id: A0A0U3T5Z5
names: Subcellular Location Annotation
messages: Membrane

2041:Aeryth RS03245
gene id: 2041:Aeryth_RS03245
uniprot id: A0A0U4CSG2
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).

2041:Aeryth RS11645
gene id: 2041:Aeryth_RS11645
uniprot id: A0A0U4BBR0
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

2041:Aeryth RS02480
gene id: 2041:Aeryth_RS02480
uniprot id: A0A0U4CRZ1
names: Similarity
messages: Belongs to the adenylyl cyclase class-3 family.

2041:Aeryth RS09565
gene id: 2041:Aeryth_RS09565
uniprot id: A0A0U4BI92
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Catalyzes the phosphorylation of D-xylulose to D-xylulose 5-phosphate.

2041:Aeryth RS08560
gene id: 2041:Aeryth_RS08560
uniprot id: A0A0U3T246
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

2041:Aeryth RS02240
gene id: 2041:Aeryth_RS02240
uniprot id: A0A0U4BXJ8
names: Similarity
messages: Belongs to the glycosyltransferase 20 family.

2041:Aeryth RS09615
gene id: 2041:Aeryth_RS09615
uniprot id: A0A0U4CAA9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

2041:Aeryth RS08115
gene id: 2041:Aeryth_RS08115
uniprot id: A0A0U4BA27
names: Subcellular Location Annotation
messages: Membrane

2041:Aeryth RS00365
gene id: 2041:Aeryth_RS00365
uniprot id: A0A0U4CQY2
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

2041:Aeryth RS08530
gene id: 2041:Aeryth_RS08530
uniprot id: A0A0U4D9A7
names: Similarity
messages: Belongs to the LOG family.

2041:Aeryth RS03640
gene id: 2041:Aeryth_RS03640
uniprot id: A0A0U4BES4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

2041:Aeryth RS06730
gene id: 2041:Aeryth_RS06730
uniprot id: A0A0U4CMR1
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

2041:Aeryth RS16765
gene id: 2041:Aeryth_RS16765
uniprot id: A0A0U3T6L2
names: Similarity
messages: Belongs to the YciI family.

2041:Aeryth RS10195
gene id: 2041:Aeryth_RS10195
uniprot id: A0A0U4CI26
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

2041:Aeryth RS09170
gene id: 2041:Aeryth_RS09170
uniprot id: A0A0U3T2H6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

2041:Aeryth RS09740
gene id: 2041:Aeryth_RS09740
uniprot id: A0A0U3KJG0
names: Function
names: Similarity
messages: Belongs to the transglycosylase MltG family.
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

2041:Aeryth RS08065
gene id: 2041:Aeryth_RS08065
uniprot id: A0A0U4C9A9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2041:Aeryth RS06720
gene id: 2041:Aeryth_RS06720
uniprot id: A0A0U4B991
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

2041:Aeryth RS05270
gene id: 2041:Aeryth_RS05270
uniprot id: A0A0U3T032
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division.

2041:Aeryth RS14420
gene id: 2041:Aeryth_RS14420
uniprot id: A0A0U4CT18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

2041:Aeryth RS13365
gene id: 2041:Aeryth_RS13365
uniprot id: A0A0U4CCM5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

2041:Aeryth RS00665
gene id: 2041:Aeryth_RS00665
uniprot id: A0A0U4CD10
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

2041:Aeryth RS13055
gene id: 2041:Aeryth_RS13055
uniprot id: A0A0U3T4K4
names: Subcellular Location Annotation
messages: Membrane

2041:Aeryth RS16350
gene id: 2041:Aeryth_RS16350
uniprot id: A0A0U4B0V3
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

2041:Aeryth RS04220
gene id: 2041:Aeryth_RS04220
uniprot id: A0A0U4CMN2
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

2041:Aeryth RS11455
gene id: 2041:Aeryth_RS11455
uniprot id: A0A0U4CQC0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

2041:Aeryth RS11295
gene id: 2041:Aeryth_RS11295
uniprot id: A0A0U4CRL8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

2041:Aeryth RS09650
gene id: 2041:Aeryth_RS09650
uniprot id: A0A0U4D9V4
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

2041:Aeryth RS16135
gene id: 2041:Aeryth_RS16135
uniprot id: A0A0U4BEB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 13 family.
messages: Cytoplasm

2041:Aeryth RS04160
gene id: 2041:Aeryth_RS04160
uniprot id: A0A0U4BF21
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system and for the release of the potassium ions to the cytoplasm.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

2041:Aeryth RS01660
gene id: 2041:Aeryth_RS01660
uniprot id: A0A0U3KEQ6
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

2041:Aeryth RS06735
gene id: 2041:Aeryth_RS06735
uniprot id: A0A0U3TFN6
names: Subunit
messages: Heterodimer of an alpha and a beta chain.

2041:Aeryth RS10660
gene id: 2041:Aeryth_RS10660
uniprot id: A0A0U4BB68
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

2041:Aeryth RS03490
gene id: 2041:Aeryth_RS03490
uniprot id: A0A0U3SZA4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

2041:Aeryth RS08585
gene id: 2041:Aeryth_RS08585
uniprot id: A0A0U4CQ65
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

2041:Aeryth RS06595
gene id: 2041:Aeryth_RS06595
uniprot id: A0A0U4CP11
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

2041:Aeryth RS12515
gene id: 2041:Aeryth_RS12515
uniprot id: A0A0U4BCK5
names: Similarity
messages: Belongs to the ACC deaminase/D-cysteine desulfhydrase family.

2041:Aeryth RS01175
gene id: 2041:Aeryth_RS01175
uniprot id: A0A0U4ASI2
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

2041:Aeryth RS04440
gene id: 2041:Aeryth_RS04440
uniprot id: A0A0U3KG60
names: Similarity
messages: Belongs to the LacAB/RpiB family.

2041:Aeryth RS04020
gene id: 2041:Aeryth_RS04020
uniprot id: A0A0U3SZJ9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

2041:Aeryth RS16835
gene id: 2041:Aeryth_RS16835
uniprot id: A0A0U4CSY8
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

2041:Aeryth RS01225
gene id: 2041:Aeryth_RS01225
uniprot id: A0A0U4B5T5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

2041:Aeryth RS13600
gene id: 2041:Aeryth_RS13600
uniprot id: A0A0U3T4M8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

2041:Aeryth RS06430
gene id: 2041:Aeryth_RS06430
uniprot id: A0A0U4BZT3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

2041:Aeryth RS09820
gene id: 2041:Aeryth_RS09820
uniprot id: A0A0U4D9Z0
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

2041:Aeryth RS05740
gene id: 2041:Aeryth_RS05740
uniprot id: A0A0U4C8Q9
names: Subcellular Location Annotation
messages: Membrane

2041:Aeryth RS16065
gene id: 2041:Aeryth_RS16065
uniprot id: A0A0U4CE43
names: Similarity
messages: Belongs to the FemABX family.

2041:Aeryth RS08580
gene id: 2041:Aeryth_RS08580
uniprot id: A0A0U4C9R8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

2041:Aeryth RS08825
gene id: 2041:Aeryth_RS08825
uniprot id: A0A0U3T201
names: Subcellular Location Annotation
messages: Membrane

2041:Aeryth RS00210
gene id: 2041:Aeryth_RS00210
uniprot id: A0A0U4BCX0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

2041:Aeryth RS01770
gene id: 2041:Aeryth_RS01770
uniprot id: A0A0U4B632
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

2041:Aeryth RS01870
gene id: 2041:Aeryth_RS01870
uniprot id: A0A0U4CLG0
names: Similarity
messages: Belongs to the biopterin-dependent aromatic amino acid hydroxylase family.

2041:Aeryth RS13305
gene id: 2041:Aeryth_RS13305
uniprot id: A0A0U3KLP3
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.